LOCUS       DATWVB010000001       105290 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.001, whole genome shotgun sequence.
ACCESSION   DATWVB010000001 DATWVB010000000
VERSION     DATWVB010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 105290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105290
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.001"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            134..1348
                     /gene="sstT"
                     /locus_tag="VCX65_000001"
     CDS             134..1348
                     /gene="sstT"
                     /locus_tag="VCX65_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEP5052503.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(1403..2077)
                     /locus_tag="VCX65_000002"
     CDS             complement(1403..2077)
                     /locus_tag="VCX65_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEP5052504.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(2087..3478)
                     /locus_tag="VCX65_000003"
     CDS             complement(2087..3478)
                     /locus_tag="VCX65_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEP5052505.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSIEAFAAIVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFERPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(3548..4261)
                     /gene="rsmG"
                     /locus_tag="VCX65_000004"
     CDS             complement(3548..4261)
                     /gene="rsmG"
                     /locus_tag="VCX65_000004"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEP5052506.1"
                     /translation="MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAI
                     TEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            4411..4968
                     /locus_tag="VCX65_000005"
     CDS             4411..4968
                     /locus_tag="VCX65_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEP5052507.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            5015..5911
                     /gene="htpX"
                     /locus_tag="VCX65_000006"
     CDS             5015..5911
                     /gene="htpX"
                     /locus_tag="VCX65_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEP5052508.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMINALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            6145..6678
                     /locus_tag="VCX65_000007"
     CDS             6145..6678
                     /locus_tag="VCX65_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEP5052509.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VRYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            6945..7631
                     /gene="covR"
                     /locus_tag="VCX65_000008"
                     /gene_synonym="csrR"
     CDS             6945..7631
                     /gene="covR"
                     /locus_tag="VCX65_000008"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEP5052510.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            7637..9139
                     /gene="covS"
                     /locus_tag="VCX65_000009"
                     /gene_synonym="csrS"
     CDS             7637..9139
                     /gene="covS"
                     /locus_tag="VCX65_000009"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HEP5052511.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHGVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETHTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMIRV
                     QGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSKES"
     gene            9354..9848
                     /gene="nrdR"
                     /locus_tag="VCX65_000010"
     CDS             9354..9848
                     /gene="nrdR"
                     /locus_tag="VCX65_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEP5052512.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            9832..11007
                     /locus_tag="VCX65_000011"
     CDS             9832..11007
                     /locus_tag="VCX65_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEP5052513.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQGDLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSRRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            11008..11910
                     /gene="dnaI"
                     /locus_tag="VCX65_000012"
     CDS             11008..11910
                     /gene="dnaI"
                     /locus_tag="VCX65_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEP5052514.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLPDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            11973..13283
                     /gene="der"
                     /locus_tag="VCX65_000013"
     CDS             11973..13283
                     /gene="der"
                     /locus_tag="VCX65_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEP5052515.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDEIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            13490..16588
                     /locus_tag="VCX65_000014"
     CDS             13490..16588
                     /locus_tag="VCX65_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP5052516.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLASNTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMKDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNENRASMSIEEIKEILGLN
                     TH"
     gene            16831..17433
                     /locus_tag="VCX65_000015"
     CDS             16831..17433
                     /locus_tag="VCX65_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052517.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQAPSSKRFCSNDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            17473..18801
                     /locus_tag="VCX65_000016"
     CDS             17473..18801
                     /locus_tag="VCX65_000016"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEP5052518.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDTALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            18847..19329
                     /locus_tag="VCX65_000017"
     CDS             18847..19329
                     /locus_tag="VCX65_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP5052519.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            19441..21015
                     /gene="mltG"
                     /locus_tag="VCX65_000018"
     CDS             19441..21015
                     /gene="mltG"
                     /locus_tag="VCX65_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEP5052520.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAARRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKGAVMTSEALKPTLLSE
                     KENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKCQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            21088..21570
                     /gene="greA"
                     /locus_tag="VCX65_000019"
     CDS             21088..21570
                     /gene="greA"
                     /locus_tag="VCX65_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEP5052521.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(22190..23113)
                     /gene="yidC"
                     /locus_tag="VCX65_000020"
     CDS             complement(22190..23113)
                     /gene="yidC"
                     /locus_tag="VCX65_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEP5052522.1"
                     /translation="MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEP
                     INKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(23195..23473)
                     /locus_tag="VCX65_000021"
     CDS             complement(23195..23473)
                     /locus_tag="VCX65_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEP5052523.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATHTLALDIGDIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGK"
     gene            23734..24471
                     /locus_tag="VCX65_000022"
     CDS             23734..24471
                     /locus_tag="VCX65_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEP5052524.1"
                     /translation="MVITSKTNQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYKTPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            24510..25010
                     /locus_tag="VCX65_000023"
     CDS             24510..25010
                     /locus_tag="VCX65_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEP5052525.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            25025..25714
                     /locus_tag="VCX65_000024"
     CDS             25025..25714
                     /locus_tag="VCX65_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEP5052526.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            25892..26134
                     /locus_tag="VCX65_000025"
     CDS             25892..26134
                     /locus_tag="VCX65_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEP5052527.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            26312..27106
                     /gene="racE"
                     /locus_tag="VCX65_000026"
     CDS             26312..27106
                     /gene="racE"
                     /locus_tag="VCX65_000026"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEP5052528.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSVQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVKHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            27103..28089
                     /locus_tag="VCX65_000027"
     CDS             27103..28089
                     /locus_tag="VCX65_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEP5052529.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQRKIKVTPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKG
                     ENGFGYDPVFIVGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            28068..28589
                     /locus_tag="VCX65_000028"
     CDS             28068..28589
                     /locus_tag="VCX65_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEP5052530.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQEVA
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            28586..29047
                     /locus_tag="VCX65_000029"
     CDS             28586..29047
                     /locus_tag="VCX65_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEP5052531.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            29044..29790
                     /gene="xerD"
                     /locus_tag="VCX65_000030"
     CDS             29044..29790
                     /gene="xerD"
                     /locus_tag="VCX65_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEP5052532.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLIGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEAYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPVTLEKYYKS"
     gene            29790..30494
                     /locus_tag="VCX65_000031"
     CDS             29790..30494
                     /locus_tag="VCX65_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEP5052533.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEEDLEQDLLEKIEEYSRFKAVS
                     QALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKTNHTV
                     IERDDYKIEDMMASIKQRLEKENVISLSAIFEECQTLNEVISIFLASLELIKLHVVFV
                     EQLSNFGAIILRKEKK"
     gene            30491..31042
                     /locus_tag="VCX65_000032"
     CDS             30491..31042
                     /locus_tag="VCX65_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEP5052534.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            31164..31886
                     /locus_tag="VCX65_000033"
     CDS             31164..31886
                     /locus_tag="VCX65_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEP5052535.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKNRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            31883..32146
                     /gene="yidD"
                     /locus_tag="VCX65_000034"
     CDS             31883..32146
                     /gene="yidD"
                     /locus_tag="VCX65_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEP5052536.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            32324..32872
                     /locus_tag="VCX65_000035"
     CDS             32324..32872
                     /locus_tag="VCX65_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEP5052537.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      32981..33105
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            33184..33747
                     /locus_tag="VCX65_000036"
     CDS             33184..33747
                     /locus_tag="VCX65_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP5052538.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFALVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            33749..34402
                     /locus_tag="VCX65_000037"
     CDS             33749..34402
                     /locus_tag="VCX65_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEP5052539.1"
                     /translation="MMTNKQTHFLIASFALLIFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQVLLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILLIGLSRIYLGVHYPSDILAGFVLGFGILHFIYPFYKQKRFEWRFLLKQD"
     gene            34695..35615
                     /locus_tag="VCX65_000038"
     CDS             34695..35615
                     /locus_tag="VCX65_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEP5052540.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            35654..36208
                     /locus_tag="VCX65_000039"
     CDS             35654..36208
                     /locus_tag="VCX65_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP5052541.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADV"
     gene            36341..37675
                     /locus_tag="VCX65_000040"
     CDS             36341..37675
                     /locus_tag="VCX65_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEP5052542.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            37753..38544
                     /gene="pflA"
                     /locus_tag="VCX65_000041"
     CDS             37753..38544
                     /gene="pflA"
                     /locus_tag="VCX65_000041"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEP5052543.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            38675..39610
                     /locus_tag="VCX65_000042"
     CDS             38675..39610
                     /locus_tag="VCX65_000042"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEP5052544.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            39686..40339
                     /locus_tag="VCX65_000043"
     CDS             39686..40339
                     /locus_tag="VCX65_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEP5052545.1"
                     /translation="MITVFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVQAGYIRRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNHVMIKEKTNITRDDLTLANYFYRLKRGEKPSAEQLDLYDLLGDVNQEYALK
                     YMTTFLLKFMRKDLVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(40384..41421)
                     /locus_tag="VCX65_000044"
     CDS             complement(40384..41421)
                     /locus_tag="VCX65_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEP5052546.1"
                     /translation="MLFMVNKKRRPLLKSHRHLLGLYTSLILLLVSLMGLALSLGESH
                     LSFLDLIHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQID
                     PTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGTNIQTGILVSLIGA
                     PYFLYLMAKTK"
     gene            complement(41382..42434)
                     /locus_tag="VCX65_000045"
     CDS             complement(41382..42434)
                     /locus_tag="VCX65_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEP5052547.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLVFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAEPGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKGYHQLRLVLAGAMVSILLSALGQGITNYYHLANAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(42424..43356)
                     /locus_tag="VCX65_000046"
     CDS             complement(42424..43356)
                     /locus_tag="VCX65_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEP5052548.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAITTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEGKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEVIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(43382..44164)
                     /locus_tag="VCX65_000047"
     CDS             complement(43382..44164)
                     /locus_tag="VCX65_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5052549.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(44410..45855)
                     /locus_tag="VCX65_000048"
     CDS             complement(44410..45855)
                     /locus_tag="VCX65_000048"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEP5052550.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMV
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIARHYL"
     gene            45943..47577
                     /locus_tag="VCX65_000049"
     CDS             45943..47577
                     /locus_tag="VCX65_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEP5052551.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSAIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAISQIAEQLIRVIWMLLTTFLIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLAAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEDRAIHLFVAVLFQTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYVFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            47745..48374
                     /gene="upp"
                     /locus_tag="VCX65_000050"
     CDS             47745..48374
                     /gene="upp"
                     /locus_tag="VCX65_000050"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEP5052552.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            48598..49188
                     /locus_tag="VCX65_000051"
     CDS             48598..49188
                     /locus_tag="VCX65_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002274529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEP5052553.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLTYGFIDEIMENNELK"
     gene            49683..49958
                     /locus_tag="VCX65_000052"
     CDS             49683..49958
                     /locus_tag="VCX65_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEP5052554.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIVYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG"
     gene            50207..50842
                     /locus_tag="VCX65_000053"
     CDS             50207..50842
                     /locus_tag="VCX65_000053"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEP5052555.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQEILTTREPGG
                     VAISEYIRELILDINHTTMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            50860..51735
                     /locus_tag="VCX65_000054"
     CDS             50860..51735
                     /locus_tag="VCX65_000054"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEP5052556.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHVNAANSLLKYIEEPQGEAYIFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQAERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            52238..52561
                     /gene="yabA"
                     /locus_tag="VCX65_000055"
     CDS             52238..52561
                     /gene="yabA"
                     /locus_tag="VCX65_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEP5052557.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            52566..53429
                     /gene="rsmI"
                     /locus_tag="VCX65_000056"
     CDS             52566..53429
                     /gene="rsmI"
                     /locus_tag="VCX65_000056"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEP5052558.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSISEILSYL
                     EETPLKGECLLIVAGAQVDSEVELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            53456..53848
                     /locus_tag="VCX65_000057"
     CDS             53456..53848
                     /locus_tag="VCX65_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052559.1"
                     /translation="MTEDQATILILGVYGIILAVFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(53895..54524)
                     /locus_tag="VCX65_000058"
     CDS             complement(53895..54524)
                     /locus_tag="VCX65_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEP5052560.1"
                     /translation="MIKEFCAENLTLLPTLDAGQVSRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTSENQ
                     LDTDAIEQLLPATQGLPLVFHMAFDRIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGVTAENCQSLSQLTGTAIVHGTKII"
     gene            54823..55179
                     /locus_tag="VCX65_000059"
     CDS             54823..55179
                     /locus_tag="VCX65_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEP5052561.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEAIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGN
                     VLQVGYRKPYQELDLG"
     gene            complement(55253..56080)
                     /gene="xth"
                     /locus_tag="VCX65_000060"
     CDS             complement(55253..56080)
                     /gene="xth"
                     /locus_tag="VCX65_000060"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEP5052562.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIETLLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDAQK
                     PVLATGDYNVAHKEIDLANPSSNRRSPGFTDEERQGFTNLLARGFTDTFRHLHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYWLASNRIVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            56314..57495
                     /gene="lctO"
                     /locus_tag="VCX65_000061"
     CDS             56314..57495
                     /gene="lctO"
                     /locus_tag="VCX65_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEP5052563.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDHLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYCSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVDHKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSIGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            57761..62698
                     /gene="scpC"
                     /locus_tag="VCX65_000062"
     CDS             57761..62698
                     /gene="scpC"
                     /locus_tag="VCX65_000062"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HEP5052564.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLMMTTTVAADELTTTSEPT
                     ITNHAQQQAQHLTNTELSSAESQSPDTSQITPKINREKEQPQGLVSEPTTTELADTDA
                     APMANTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS
                     MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFD
                     EDWENFEFDAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKYES
                     HGMHVTGIVAGNSKEAAATGERFLGIAPETQVMFMRVFANDVMGSAESLFIKAIEDAV
                     ALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLA
                     TNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVDFK
                     DIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAKKHGAL
                     GVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLEFDSVVSKA
                     PSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAGA
                     SLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNIDG
                     AVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQKG
                     RFTLTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRD
                     SQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGKHF
                     TGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNNQD
                     FAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTLLG
                     TAFSGKSLTGAELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPET
                     NRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQADG
                     SFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKETL
                     KDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKGLK
                     NNVYNDLTVNVYAKDDHQKQTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQYV
                     VTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVREEV
                     FYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRA
                     GNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNN
                     SGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKMTMLATSQIT
                     AHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRIEG
                     NTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSATAK
                     ALPSAGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            63471..64178
                     /locus_tag="VCX65_000063"
     CDS             63471..64178
                     /locus_tag="VCX65_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEP5052565.1"
                     /translation="MSKKKRKHYQVYDGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWATKKGLHWYLLSSVIL
                     TGIAFGMALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
     gene            64418..66418
                     /gene="metG"
                     /locus_tag="VCX65_000064"
     CDS             64418..66418
                     /gene="metG"
                     /locus_tag="VCX65_000064"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEP5052566.1"
                     /translation="MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLEEVFRDEDGKVIGGIAPSGH
                     QVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRT
                     TFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQANHANFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGT
                     AFDADFSQLIDAQLADYHKHMEAVDYPRALEAIWTIIARTNKYIDETAPWVLAKEDGD
                     KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLAPVSDLSTLALADFPANTK
                     VVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSEKDVITFETFDA
                     VEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKCYPNEQELVGKKLQIVA
                     NLKPRKMMKQYISQGMILSAEHGDQLTVLTVDSSVPNGSIIG"
     gene            66909..67922
                     /gene="nrdF"
                     /locus_tag="VCX65_000065"
     CDS             66909..67922
                     /gene="nrdF"
                     /locus_tag="VCX65_000065"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEP5052567.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRSRVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYDSPFTDEETRISPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            67926..68414
                     /gene="nrdI"
                     /locus_tag="VCX65_000066"
     CDS             67926..68414
                     /gene="nrdI"
                     /locus_tag="VCX65_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEP5052568.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQINNLITERTHPCHKPMRHT
                     SH"
     gene            68381..70561
                     /gene="nrdE"
                     /locus_tag="VCX65_000067"
     CDS             68381..70561
                     /gene="nrdE"
                     /locus_tag="VCX65_000067"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEP5052569.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRAYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKFFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVETGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYAFKASCQLA
                     KEKGAFAGFSLSTYADGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECQSCMI"
     gene            complement(70766..71518)
                     /locus_tag="VCX65_000068"
     CDS             complement(70766..71518)
                     /locus_tag="VCX65_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEP5052570.1"
                     /translation="MLKKRYQLAMILLLSCFSLVWQTEGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKGAETLIKKRWGKGLVYPRAEQEAMAAYTCQQAAPINTSLDKTKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDQKKLHIEAYFKGSL"
     gene            71975..72427
                     /locus_tag="VCX65_000069"
     CDS             71975..72427
                     /locus_tag="VCX65_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052571.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMTRPVKAEVSEIGHDHVTIS
                     SNGQTDEGAAYGRGHDDGSKFGYEAGLQSSWNESEPPSSDKIPEPSVNPYESSNEQDR
                     EDYKEGFRDGYPGGYVAGWRKTHPIEATLQYLWYTVSSWFESLFNNSK"
     gene            complement(72734..73986)
                     /locus_tag="VCX65_000070"
                     /pseudo
     CDS             complement(72734..73986)
                     /locus_tag="VCX65_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            74442..74915
                     /locus_tag="VCX65_000071"
     CDS             74442..74915
                     /locus_tag="VCX65_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052572.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMGQPIKAEAVVSDLNDAVSS
                     MGDTAEETDVNIDGQEDEEDEEDDAYMQGRRLGEKEGYEAGQKDNAPRLFDSSTLEPP
                     TNPYEDAGDTLNSNWFKSGYSDAYGQAYEQGWNDTHPIQSTLIWLWGIVRNLFRF"
     gene            75168..75419
                     /locus_tag="VCX65_000072"
     CDS             75168..75419
                     /locus_tag="VCX65_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052573.1"
                     /translation="MPEKKVLPVLSMVVSFVCLLDHIFFFATYSYLYLPLVASSLALI
                     SLVQNKGRQKVWSLAGLILAALAVAVVAYAYYDPTVIPY"
     gene            complement(75792..76292)
                     /locus_tag="VCX65_000073"
     CDS             complement(75792..76292)
                     /locus_tag="VCX65_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052574.1"
                     /translation="MKKTLTLLLALFTIGVTSSVRAEESSWVPLPRQQKVLDDNRNEI
                     PVHITGNKVTVTLPPGWSAWIDKNTKQRNSNSVTTTVTLDISTSQPPKEFTIYFQGDD
                     GFLAGMMTFIDSETLKNEQYKAFDEEYAENLFENSRLREEQKTWRDKVRDVFQDAWWN
                     FKGLFQ"
     gene            complement(76560..77258)
                     /gene="spej"
                     /locus_tag="VCX65_000074"
     CDS             complement(76560..77258)
                     /gene="spej"
                     /locus_tag="VCX65_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeJ"
                     /protein_id="HEP5052575.1"
                     /translation="MKRLIKTIILVIIIFHGYGSVKSDSEKIKDVKLQLNYAYEIRPV
                     DYTNCNIDYLTTHDFYIDVSSYKKKNFSVDSEVESYITTKFTKNQKVNIFGLPYIFTR
                     YDVYYIYGGVTPSVNSNSENSKIVGNLLIDGVQQKTLINPIKIDKRIFTIQEFDFKIR
                     QYLMQTYKIYDPNSPYIKGQLEIAINGNKHESFNLYDATSSSTRSDIFKKYKDNKTIN
                     MKDFSHFDIYLWTK"
     gene            complement(77460..77597)
                     /locus_tag="VCX65_000075"
     CDS             complement(77460..77597)
                     /locus_tag="VCX65_000075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052576.1"
                     /translation="MLTYHELKKAVANRYIKGDMISITRKLVSSLILSFLIELYEYQE
                     F"
     gene            77828..78111
                     /locus_tag="VCX65_000076"
                     /pseudo
     CDS             77828..78111
                     /locus_tag="VCX65_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            78285..78866
                     /locus_tag="VCX65_000077"
     CDS             78285..78866
                     /locus_tag="VCX65_000077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052577.1"
                     /translation="MKTRPKRFLNLATLSLALLGTTLLMAQPVKADNDTRESQERVDQ
                     RIEDPYDDGKNAGRKDGYESGNHKGISEEPPTKTPEPPTNPYSRDRVKSKKYRDGYQE
                     WYVYGYYEGWHRANDEDKNKESSDHSRDQDLEGTEQTDGQDEDKNKESSDHSRNQDLE
                     GTEQTDTEYSAIISTLYGIAGVVLEYVLSWFSI"
     gene            79526..79762
                     /locus_tag="VCX65_000078"
     CDS             79526..79762
                     /locus_tag="VCX65_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEP5052578.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGEGEGFSMWAPTPCDVLAEDWIEVND"
     gene            79755..80453
                     /locus_tag="VCX65_000079"
     CDS             79755..80453
                     /locus_tag="VCX65_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEP5052579.1"
                     /translation="MTKVVLVTGCASGIGYAQARYFLRQGYHVYGVDKSDKPDLSGNF
                     HFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTASDFEPGGLAEWVARETPIGRWTEPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            80529..81488
                     /locus_tag="VCX65_000080"
     CDS             80529..81488
                     /locus_tag="VCX65_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEP5052580.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLKTAKDLA
                     KAYHMPLATSEYEAVLGNEEIDTVYIGLPNHLHFAYAKEALLAGKHVICEKPFTMTAG
                     ELDELVVIAKKRKLILLEAITNQYLNNMTFIKEHLDQLGDIKIVECNYSQYSSRYDVF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANVEKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKTTIQGNKGSLAVLGATNTLPQVQLSLHGHEAQVVNHNKY
                     DHRMYEEFVAFRDMIDQRDFEKVNQALEHSRAVMAVLERAVHS"
     gene            81821..83158
                     /locus_tag="VCX65_000081"
     CDS             81821..83158
                     /locus_tag="VCX65_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP5052581.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            83331..84713
                     /gene="glmU"
                     /locus_tag="VCX65_000082"
     CDS             83331..84713
                     /gene="glmU"
                     /locus_tag="VCX65_000082"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEP5052582.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKSVTVIGHKSEMVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVTIFRANKEKVGAYILR
                     DFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGDNCVVTNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEVGDHALTAAGSTISKTVPIDSIAIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            84744..85298
                     /locus_tag="VCX65_000083"
     CDS             84744..85298
                     /locus_tag="VCX65_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEP5052583.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKILLVKQYRKAIERVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            85298..85549
                     /locus_tag="VCX65_000084"
     CDS             85298..85549
                     /locus_tag="VCX65_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052584.1"
                     /translation="MGRPLLTDDIIEKARRMETFESDDAVDFDTKVMTLPEKDDKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            85569..86264
                     /locus_tag="VCX65_000085"
     CDS             85569..86264
                     /locus_tag="VCX65_000085"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEP5052585.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQILMTFLENLPV"
     gene            86415..86756
                     /locus_tag="VCX65_000086"
     CDS             86415..86756
                     /locus_tag="VCX65_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052586.1"
                     /translation="MTLKKHYYLLSLLALVTVGAAFNTSQSVSAQVYSNGRYRQGLTD
                     EKSKLQYSKDNAKLQLRNILNGYQSDLGRHYSSYYYYNLRTVMGLSKEQEIEKYYEEL
                     KNKLHDMYNHY"
     gene            complement(86855..87502)
                     /locus_tag="VCX65_000087"
     CDS             complement(86855..87502)
                     /locus_tag="VCX65_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEP5052587.1"
                     /translation="MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDTFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLEAHHLSINTELTLTQIDTFAKTYTICYGDKELVIPENIAKQLYVTAL"
     gene            87647..88579
                     /locus_tag="VCX65_000088"
     CDS             87647..88579
                     /locus_tag="VCX65_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEP5052588.1"
                     /translation="MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            88643..89368
                     /locus_tag="VCX65_000089"
     CDS             88643..89368
                     /locus_tag="VCX65_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEP5052589.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIEGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            89369..90223
                     /locus_tag="VCX65_000090"
     CDS             89369..90223
                     /locus_tag="VCX65_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEP5052590.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLVVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(90370..91176)
                     /locus_tag="VCX65_000091"
     CDS             complement(90370..91176)
                     /locus_tag="VCX65_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEP5052591.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPKQDITITSIDIVKDYRFKN"
     gene            91393..93798
                     /locus_tag="VCX65_000092"
     CDS             91393..93798
                     /locus_tag="VCX65_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEP5052592.1"
                     /translation="MVKRNQRRKSAPKKCLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMPKEPEILAYDSHLK
                     DDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVDVDFTPKTHLLYKLPTI
                     DLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNIA
                     GYNAKVEDYNRQSEQKQMPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(93868..94221)
                     /locus_tag="VCX65_000093"
     CDS             complement(93868..94221)
                     /locus_tag="VCX65_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEP5052593.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTPLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            94460..94831
                     /locus_tag="VCX65_000094"
     CDS             94460..94831
                     /locus_tag="VCX65_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052594.1"
                     /translation="MSNNLEIVMDIETLDIFEVIDLDEEKEVTVSDSETFPKEEKASP
                     YDDLNRIWLRNGYYYKPSSLLWEVIENGIIHDLSPRNKHGTYPYYQHSRDGTWGHVKQ
                     LTQEEALWLTLELNPDLMNYV"
     gene            95015..95278
                     /locus_tag="VCX65_000095"
     CDS             95015..95278
                     /locus_tag="VCX65_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HEP5052595.1"
                     /translation="MTQHLLNCYPEYFEAIMDGTKTFECRYNDRDFKVGDELLLREYD
                     PKKGYTYPYRCIVRKITYILSDFIGLKDGYVILGVTNEPIDYF"
     gene            95433..95993
                     /locus_tag="VCX65_000096"
     CDS             95433..95993
                     /locus_tag="VCX65_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5052596.1"
                     /translation="MSNRLKELRKEKGLTQAELAQIINTNQSQYGKYENGKTNLSLEN
                     AKILADYFGVSPAYLLGLETEFEPVESRETQFQMLVKDRKLSLREISEDTGINYSTIG
                     NYNQGTRIPNARNAAILADYFRVSVGYLLGYEKEPNLIKAEPLILTKLIQELSSINYQ
                     KEEILQVYLELAKKEQAILKKIKERI"
     gene            96033..96569
                     /locus_tag="VCX65_000097"
     CDS             96033..96569
                     /locus_tag="VCX65_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000941151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5052597.1"
                     /translation="MLQNRLKQLMLKKHKTVEQVSQETGIKKGSLEMYILGKDIMTDD
                     LDILTRYFQTNSPYLTGIWGIAADEKHVTHFRKLFKDSSYYFMPDVSDIFEDLDNCFY
                     NFWIQSLEFTVLENNGRAERFFKELTFHPQDDCVFITVSDRYVIEALESYNQIIRYHY
                     PEGGDYTPVLIFKGKAIK"
     gene            96606..97478
                     /locus_tag="VCX65_000098"
     CDS             96606..97478
                     /locus_tag="VCX65_000098"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5052598.1"
                     /translation="MPNRIKELRKQKGVTLNDLSLATGFTTSSISRWEEGSRGFDKEK
                     AILMAKILEVKPSELFISDENNFQTYWNTEKNITFRGDKYIVSIMRKGKKYSRSFDKL
                     EEAIRHRDIILKDYKETGILPKTRTEEIISSYRELIGKKFRRLTVIDIVGPKKKKDVK
                     RTYTYLLCHCDCGNTCEVEIFNLLKGTILSCGCLALEKSQEIGKRFGKDSETSEKARV
                     SNILNSNPRKTNKTTQIKNITYSPKLKSYRVQITRRGVHYTKRFPSLAEAIDYKEVVL
                     NQLDKDVRQKQVKK"
     gene            97528..97710
                     /locus_tag="VCX65_000099"
     CDS             97528..97710
                     /locus_tag="VCX65_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052599.1"
                     /translation="MKPKQSAVAKLTKNMMVVDIMKQTGWSRDRALAAVEELEEQQLI
                     HFLSQGGMRLQVIGGL"
     gene            97710..98843
                     /locus_tag="VCX65_000100"
     CDS             97710..98843
                     /locus_tag="VCX65_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEP5052600.1"
                     /translation="MADITIDQLATQTFYQVPEIFFTRIQHNEDGYVKLTSPYVSLSS
                     DAKLAYGALYNRCKLSISSFQKGNRDYVDENGAVFLIFTVTDLMLLLDKGKMKVTQIK
                     KDLQEHGLLREVRQGLNKPNRLYLQLVDSSLEVAEYYDAEGELFKKVNAFGKVIFQKE
                     DISQKTAETLGNSGSPFFGRPKSGRQKVHKMDAIKTEKSQTESDDTNRYQDEIPLSTL
                     SDSDAFQMGRHGFLSTQTIQRLSLFGKEAKLLENKIYQAKRQIEKDYSHLLQNQEIIY
                     GEVWSQELEREVDKLIFKIKTGENEGKPIKNIPGYFYKMMVHFWKMALLIEKEQGFVS
                     LANQSEYTKQYSEECPSLIAYYYPDKLSESKLNQYLTALQMEV"
     gene            98845..99534
                     /locus_tag="VCX65_000101"
     CDS             98845..99534
                     /locus_tag="VCX65_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052601.1"
                     /translation="MLDKPSRNSPRDKLKNHLKACQTPLKNYPLKAVFLAVIFIAIVF
                     SFFSQILISLKAMGFTTLSLLILLVLGYPCHLQSLYHDLKLSIYQYQQDKIDFFKTYG
                     EKQEDVIDDIRIIYETDNTVTVQFIYQGQPSQLSLSKGAIPQSYANQQLVVIARCRAI
                     AKEHLSAYLILFETRDLAQKYQTILKHPIITEGLLSDNDILQLSEAPDKPMVSFQLAL
                     ITQPKESETSK"
     gene            99531..99671
                     /locus_tag="VCX65_000102"
     CDS             99531..99671
                     /locus_tag="VCX65_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052602.1"
                     /translation="MIIKERNGFLTIPKSIFSLPPEEKTQALKELEEEMEQHKAKGGD
                     ST"
     gene            99668..99886
                     /locus_tag="VCX65_000103"
     CDS             99668..99886
                     /locus_tag="VCX65_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5052603.1"
                     /translation="MTTITQNRVKELRKQAGLSQQALADQIGVMRKTISHWELGNHRI
                     STDNAKKLSQFFQVSIDDLLNNHARRSQ"
     gene            99883..100209
                     /gene="ssb"
                     /locus_tag="VCX65_000104"
     CDS             99883..100209
                     /gene="ssb"
                     /locus_tag="VCX65_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEP5052604.1"
                     /translation="MNNTNLIGRLTKKAELYQTPDKKTYARFTIAINRKKKAGGSGSE
                     ADFIPCIIWGKAAENLVNWTDKGTLISLEGELRTRNYEKDGQRHFVMEVWSTFFQVLS
                     KPANDN"
     gene            100235..102520
                     /locus_tag="VCX65_000105"
     CDS             100235..102520
                     /locus_tag="VCX65_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HEP5052605.1"
                     /translation="MKQVKVLTGIAVAALSTGTGLVQADDLSNTRPAKAAEVVTHTEV
                     TENQVADAKTKADEATKAVKDQEATVKAIEAEKSQAQQSLVNATTAVNDTEKLASEAT
                     PDGLTKAQDEAEASQSAVTDAQAQLEAAQEAESTAQTAVDHQKETVAKASQAVVEKEA
                     TVTSATQAVNQAKAALTTTNQAVDVSAAEEKVLEAQEAVTKAETQVSQAQEADAKHGS
                     DVSHAKEELDLKFQELAEKQTTLEQVMAAIEAERLTKSVENGTYFNQRDNEWQKAYGG
                     KTFAATGCVPASLAMAFSELVGRHISPLEVADYLYQIGEFNNGRFDGTSSIGAMKAAE
                     HFGLVPTVLKTLDQVQTALQDGHYVINSIQHHEKFAPLSWGWSASHDVALRGYQDGNT
                     YVYDPYNRNNIGYHNLADLWNHQSHNPEDVDGVGVPFISLMTKQMAQLMAEKVTVNQA
                     VQLANQALTEAQANVTALEQVASQTSQAKDQLAAAKANLVTAKDMLDKAKQRAKLTEQ
                     DLETKTAILKQAQEHLTLKQDDLAKAQRVLAAQETSLEQLTQALSLAQANLGRATKAV
                     EQAKADFTQKQAYVTNLKQVTKLRQESQDKVNQAKAVLSEASARLERELETLKTLQAK
                     EADLTAQYQAIFKAYQAVLAAKHHSQLAESKAKLEAKGEEAVPVVNEVGHVTDYVSGT
                     TQLADGVAVRTEETSSKTMNTSLVSVQPMDKQGHQRVLGATTSQSSLPQTGEQSVSLL
                     SLLGMTLVSLLGLVSVKKKAE"
     gene            102887..103192
                     /locus_tag="VCX65_000106"
     CDS             102887..103192
                     /locus_tag="VCX65_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052606.1"
                     /translation="MIDENETVVTLSDLKQLGKQGGATALLEDGTLLTLRGRHATRRT
                     KGYVDGILKEIDVIIPYPKILNQIRTIKSQNTLVARRINRQSPLRLTGRGYHRKGKE"
     gene            103198..103893
                     /locus_tag="VCX65_000107"
     CDS             103198..103893
                     /locus_tag="VCX65_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP5052607.1"
                     /translation="MTKKQLLSVLTATTVALLTTSLAYADETPVPVDPTAPSTEVVTP
                     APAQPEKLPDTSKPAEPETPKEERPAPVDPTTPSTGKEDKPETPSVPETPKEETKPKE
                     EVTPETPKSSEDKKKEELVPDNVSKDIIEKVDTTTGEVVFKPIPVTPDKTVIGTKDSQ
                     VIIRDQAGRTQVVTPESLGGHVNPNGTVTITDSTGAKKTLPKTGDKQSVLGYLGMMLV
                     SALGYAVKKKVSH"
     gene            103950..>105290
                     /locus_tag="VCX65_000108"
     CDS             103950..>105290
                     /locus_tag="VCX65_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEP5052608.1"
                     /translation="MKQMKTKGHGYFRKSKAYGLVPVIALGSLVLMGTTSVSADDVTP
                     LNPATNLTTLQTPPAADQTQLAHQAGQQSGELVSEVSSTEWDNAVTTAQKAGVTVKQS
                     EKVTHDSLSSAQADLEKQTQAVTEATTKQEANTTAINQAVSENKAIDQANRDEKARVD
                     ALNTKEEADTKAKNEAGQAQVDAQNKQAQEAADAMNAQLKADYEAKLTEIERLKAENE
                     AIRQRNQQASQATHQANQAAQAAYQEKLAEIERIKAENATIRDRNAKAQQEAERQNQA
                     LQAAYEAKLAEIKQIESENEAIRKRNEQAGQATNQTNQAAQVEYQQKLAEIERIKAEN
                     AAIRDRNAKAQQEAERQSQALQAAYEAKLAEIKQIESENAAIRQRNEQAGQTTNQTNQ
                     AAQAAYQEKLAEIERINAENAAIRDRNAKARQEAERQNQQLKTTYEAKLTAYQQA"
BASE COUNT        33385 a        19194 c        21915 g        30796 t
ORIGIN      
        1 ttcgatagtc aatagaaatt gactgaaaat tcttagcaca aaaaatggtt aagatatgta
       61 gctcattcga tttgacgaat agatagaatt atattattat aaaaaacatg taactttagt
      121 aaggatgtaa cgtatgaaaa aaatatatga tttatgggtt agggttagtc taatcaaaaa
      181 aataggtatc ggtgttgtaa taggagtcat gttgggcatt ttggctcctg atcttacagg
      241 ttttagtatt ttaggaaagt tatttgttgg tggtttaaag gctatcgcac ctttgcttgt
      301 atttgctttg gtttcccaag ccatctccca tcagaaaaaa gggaaacaga ctaatatgac
      361 attaatcatt gttctgtatt tatttggtac ctttgcgtca gctttagtag cagtactgac
      421 agcttatcta ttccctttga cgttagtgtt aaatacacct gtaaatacag aattatcacc
      481 acctcaaggt gttgctgaag tttttcagtc acttctatta aaattagtgg ataatccgat
      541 caatgcttta gctactgcca attatattgg tgtgctatca tgggcaatta tttttggact
      601 agcattaaag gctgcaagtc aagaaacaaa gcatcttata aaaacagcgg cagaagttac
      661 ttcacaaata gttgtttgga tcatcaatct ggcacctatt gggattatga gtctggtgtt
      721 cactacgatt tctgaaaacg gtgttggaat cttatctgat tatgcttttt tgatactagt
      781 tttagtagga acaatggttt ttgtcgcctt agtggttaat ccacttattg cggttttgat
      841 tacacgacaa aatccttatc cccttgtctt gagatgttta cgtgagtcag gtcttacagc
      901 atttttcaca cgaagttctg cagccaatat tccagtcaat atgcaattat gccaaaaaat
      961 tggattgagt aaagatactt attcagtgtc aattccactt ggagcaacta ttaatatggg
     1021 tggggcagca attaccatca atgtcctaac gcttgctgct gtacacactt ttggtattcc
     1081 tattgatttt ctaacagccc tcttacttag cgttgttgct gctgtctctg cttgtggtgc
     1141 ttctggtgtt gctgggggat cgttgttact tattcctgta gcatgtagtt tgtttggcat
     1201 ctcaaatgat cttgcgatgc aggtggttgg tgttggtttt attgttggtg ttatccagga
     1261 ttcttgtgag acagccttaa attcgtcaac cgatgttctt tttacagcta ttgctgaaaa
     1321 tgctttttgg aaacgtaaaa aagcctagct aggtttaaca tagtaaaaaa catccttgga
     1381 aaacgccaag gatgtttttt tattatttaa gatagccaag ataatcaaat ttttcaaagg
     1441 tgtggtcatt agcgatggct acaatgatag tattcggttc taaaggttca aaaggtttga
     1501 cattggtatc taaggtttta acttcttttt gacgcatgcc aatcacattt aactcatatt
     1561 tacgacgaac atctagttcg gaaagagatt gtccttccca gcttttagga atgacaaatt
     1621 caatcatgga aatgccatgt tcgaggtaga tgatgctttc gatatgacgt cttaacagat
     1681 ttgaagctac acgttttcca gaatcacgtt caggggtgat gactttagtt gccccgatgc
     1741 catatagaac ttcttcaaaa attttatttt tagccttggc aataatggtt ggaacaccga
     1801 gttttttaca gtgcatgact gcaagaacag aagattccaa gttattccct gaagcgataa
     1861 cgacagtatc acaatgttca atccctacag ctaatagaaa ttctttgtca gtaatatctc
     1921 caacagcggc tttagtgacc aagtcggcca cctctttaac atgactttct ctgatatcaa
     1981 tagcaataac gtcttgatca aaattactta attctctggc aacagtacgg ccaaaaatac
     2041 caaggccaag aacgccgaca gttttacgtt ttaacatgtt ttctccttaa cccactaaaa
     2101 tatcagtagt ggcatattga atggtttttt cttttcgttg aatcagactg atgaggacag
     2161 taattgggcc aacgcggccg acgaacatca agacaatgac aataagacgt ccagcagtag
     2221 acaattgtgg tgtcaaatcc atagataccc caactgtcgc gatggcagaa atagattcaa
     2281 ataagagtgg tataggagcg atatgaggct ccacgctaag taataaaata aaacctatca
     2341 taagaactgc aaaaaagaag ataagaactg tcatggtctg cttaattgtc ttatttgcga
     2401 taattcggtt acgaaaggta acttctgatt gccctgaaag ttccgcttta aagagtaaga
     2461 aagtaatggc agcagtcgtc actttaatac caccagctgt tccaccagga gcaccaccaa
     2521 taaccatttg aatcatataa agaatgttag tcggtgctag ggtatcgtta taagagattg
     2581 ttgcaaagcc agctgttctc atagtgactg tttgaaaaaa tgaaaccata agttgctgat
     2641 gtaaactaaa attggcaatg gttttgctgt tatctttttc taaaaaccag gttaagaagg
     2701 ttccaagaaa aagaataaca gctgtggttt gtagtactag acgagactga ttggataatt
     2761 tacgaaaagt tgccccataa caatgaggtc tttcaaaaaa gtatttttta aaagctactc
     2821 ctaaatcaac ccaaaccgca aaaccaagtc caccagagat aatcaagaac gtaatgataa
     2881 catttaatgt aggatttaac ataaagtctt ttaaactaga agatcctaaa ttgtcaaaac
     2941 cagcgttaca aaatgccgac acagctagaa aaatactatt gaagatacca tttttccacc
     3001 cgaagcgggg gataaagtca atcatgataa ctatcgcagc aaaggcttct atactaaagg
     3061 ttactttata agcaaaaaaa aggtagtgct ttaaatcttt gctatcacct cgatttaacg
     3121 ctgattggag caaggtttga tcgctcaatc gcatttttcg cttgagggca aaagtactca
     3181 cagctattaa cgtcaccaag ccaagaccac caatctgcat tagtgccata gcaatggttt
     3241 gtccgatacc gttatacact tcagcgacgg gaacaacaga aagtccagtc acacaaacca
     3301 tggaaaccac attaaagaaa tgatcaagat agacggtatt aggaccattt tgataatggg
     3361 taaagggcat ggataacaag agagtcccaa tcagaatcac aatggcaaaa ctaaatgtta
     3421 agcgctgtgt gactgaaaga gatttgataa aagagcgttt catgtttcct ccagacataa
     3481 tatctcctac tataataaca aaaataagtt aaaaaagcta agtttcatct tagcctttgg
     3541 tactatttta tagaggtttt ttgttaggca agccagcttt tcttggatac ttgttaggtg
     3601 tttccttttt cttctcaaca atggtgatga agcgagaatc tccatttggc aattggtagc
     3661 tatggttttt aatgacttta ccaaaaagaa gacaaagagc attcttagct tcttctaact
     3721 cttggtcagc agcttgtgcc tttaaggcga ttaattttcc tccaattttt aaaaagggga
     3781 tggttaattc agatagaacc tgcatccgag caaccgctct ggcagtaacg acatcaaatt
     3841 gacctcgaaa ggccttgtcc tgtccgaaat cttctgctct accatgaaaa aaatggacat
     3901 tttccaagcc caattcctga gcaaggagtg tcagaaaaga aatccgctta ttaagagaat
     3961 caataatggt aacctcaagg ttcgggaaaa gaattttcat gggtaggcta ggaaaaccag
     4021 ctccagctcc aatgtccaat aatttgattg gttcattagc taaaaagccc tgtaaaatag
     4081 gagcgatgga atcataaaaa tgcttgaggt aaacctcatt ttcttctgta atagctgtta
     4141 aattaatttt agtgttccat tccactagta atttaaagta ggtgtcaaat tgttcttttt
     4201 gtttcgatga taaggaaaaa ccatcttcct ctagtgttcg gtaaaagtct tggggtgtca
     4261 tttgtatcct ctgtttttga tagttgttac cattttatca taaaatagcc cataacaaaa
     4321 tccaataaat catcagaaat aacacctcat tacttgctat tagcctagaa attgctataa
     4381 ttgagacaca aagattaaag gagacccact atgccaacag ttttgattat cttagtcgtt
     4441 ttaggagtgc ttgcgctatg gttaatgatt agttacaata gcctggttaa atctcggatg
     4501 cacacaaaag aagcttggag tcagattgat gtgcaattaa agcgtcgtaa tgacttgatt
     4561 ccaaatctta ttgaaaccgt aaagggatat gctagctacg agcaaaagac atttgaaaaa
     4621 atcactgatt tgcgtgcgcg tgttgcgaat gcctcaactc ctcaagaaac catggcggct
     4681 tctaacgaat tgagtaaaca agtgaccagt ttgtttgccg ttgctgaaaa ttacccagac
     4741 ttaaaagcta acgaaaactt cttgaaatta caagaagagt tgaccaatac ggaaaataaa
     4801 atctcatatt ctcgtcaact ctataattca acaacgtcta attacaacct tcaattagaa
     4861 tctttcccaa gcaatatcgc tggtaaatta tttggtttta aaccaagtga attcttacaa
     4921 acaccagaag ctgaaaaaga agttccaaaa gttgaattta acttttaaat atgaaattat
     4981 catctagtag gcaatcataa gagaaaggag aattatgctt tatcaacaga tttcacaaaa
     5041 taagcaacga acagttgttt tattagttgt tttcttcgct ctcttagcac ttattggagc
     5101 ttcagcaggc tatctgctgt tagataatta tgccatgggc ttggttcttg ctcttgtcat
     5161 tggggtgatt tatgctacca gtatgatttt tcaatccacc agtcttgtaa tgagtatgaa
     5221 caatgctaga gaagtcacag aaaaagaggc tccaggcttc ttccatattg tcgaggatat
     5281 ggctatggtg gctcagattc cgatgccgag agtttttatt attgaagatc cttctttaaa
     5341 tgcttttgcg acaggatcta gccctcaaaa tgctgctgtt gcagcaacga caggtttact
     5401 tgaagtcatg aatcgtgaag aacttgaagg tgttatcggc catgaaatta gccacatccg
     5461 aaattatgat atccgtattt cgactattgc tgtagctttg gcgagtgctg ttaccgttat
     5521 ttctagtatc ggtgggcgta tgctatggta tggtggcggt tctcgcaggc aaagagatga
     5581 cggagatgat gatgttttaa gaatcattac attacttttg tcgttattat ctttgctttt
     5641 agcgccccta gtagcaagtt tgattcagtt ggctatttct cgtcaaagag aatatctagc
     5701 tgatgctagt tctgttgaac taacaagaaa tccccaaggt atgattaacg ctcttgaaaa
     5761 attgcagtta tctcagccaa tgaagcatcc tgttgatgat gctagtgcag ccttgtatat
     5821 taatgagcct cgcaaaaaaa ggagcttcag ttcattattc agcacccatc ctcctattga
     5881 ggagaggatt gaaaggctaa aaaacatgtg agcgtttggg gtttttgctc aaacctcact
     5941 tttttatgtc tttgggcaga taatctaaaa tggcaggaat tatcaaaaat atctgaacaa
     6001 aaagaaaaaa atgagtgaaa caatggttaa aaatagaatg atttaaatct taaaattaaa
     6061 aaacgtcaga aaataaatgc aaaactattg acaaatcttt tagatagtag taaaaataaa
     6121 tgagagtttt attaggagaa gatgatgtta gctatttccg aaatcagaaa acacccagac
     6181 ggtctctcgt ttgatcgttt atgtgatgtc aaaagtatgt tacttgagcg tgaccaacag
     6241 attattgaca taaaggcagt taaagctgtc ggtaatgttc gctatgataa ggggctttat
     6301 ctgttagatt atcaattgag ttacgaagtg atattaccgt ctagccgttc tatggttccg
     6361 gtctgtttaa gtgaagtcca acacattcaa gaattattta tagaggcgac agatttagct
     6421 gataagaaag agttggttga agacaatctg gtattagttt tagacaaaga cgctattaac
     6481 ctcgaagaaa gtattgtgga taatatctta cttgctattc cgctacaggt cttgacagag
     6541 gaagaaaaga aatcaaaaga gttgccagca ggtcaaaatt gggcagtttt gacagaagaa
     6601 gactaccagt gtctaaaaga agaaaagcaa aaagaaaata atccttttgc tagcttgcaa
     6661 gggttgtttg atgaataaaa ctgaatatta aagatgtctg taatttttat ttgaaaaaac
     6721 agctattctt tgatatactc tttagagaat atggttactt atctaaagta gaaggtattt
     6781 tgaccataga gggcaaagaa ggtaatgact attagatgct tcatatttta ttcgctagaa
     6841 gactatttga ccattagaac tgaaatagtc taggatatga gatgaatttc atagttttct
     6901 ttctgggaga aaaagataga ttaagaggat aagggttggt ataaatgaca aagaaaattt
     6961 taattattga agatgaaaag aatctggcta gattcgtttc tcttgagctg caacatgagg
     7021 gttacgaagt cattgttgag gtcaatggtc gtgaagggtt agaaactgct ttggaaaaag
     7081 agtttgattt aatcctgctt gacttaatgt taccagagat ggatggtttt gaagtgaccc
     7141 gtcgtttgca aaccgaaaaa acaacgtata tcatgatgat gactgcgcgt gattctatta
     7201 tggatgtggt tgcaggttta gaccgcggtg cagacgacta tattgttaaa ccgtttgcca
     7261 ttgaagaact acttgcccgt attcgtgcta ttttccgccg tcaagatatt gaatctgaga
     7321 agaaagtgcc tagtcaaggc atttatcgag atctagtttt aaatccacaa aaccgttcag
     7381 ttaatcgtgg cgacgatgag atttctctca ctaaacgtga atatgatttg cttaatattt
     7441 tgatgactaa tatgaatcgt gtcatgacac gtgaagaatt attgtcaaat gtttggaaat
     7501 atgatgaagc cgttgagact aatgttgtag atgtctatat tcgttatctc cgcggcaaaa
     7561 ttgacattcc aggcaaggaa tcttatatcc aaacagtgcg tggcatggga tacgttattc
     7621 gtgagaaata agtcatatgg aaaatcagaa acaaaaacag aagaaatata aaaattcgtt
     7681 accaaaacga ctatctaata tcttttttgt tctttttttc tgcattttct ctgcctttac
     7741 actgattgcc tatagttcaa caaactattt cttattgaag aaagaaaagc agtcagtctt
     7801 tcaagctgta aatattgtta gagttcgtct ttctgaggtg gactctaatt ttacattaga
     7861 gaacttagca gaagttttgt acaaaaacga taaaacacat ctgagaattg atgacagaaa
     7921 gggcagtcga gtcattagga gtgagcgcga tatcacaaat actctagatg cgaatcaaga
     7981 tatttatgtc tataacattg ataagcagat gatttttacc acagataacg aagaatcatc
     8041 tcctggcttg catggtccta tcggtcgggt gtatcacgac catatcgaag atcagtatcg
     8101 tgggttttcc atgacacaaa aggtatattc taatcggact ggaaaatttg tgggctatgt
     8161 tcaagtcttt catgatttag gcaattatta tgtcattaga gcaagactgc tgttttggct
     8221 actagttgtt gagttatttg gcacaagctt agcctattta atcatcttaa ttactacgcg
     8281 gcgctttttg aagcctttac acaatttaca tggagtaatg cgtaatatct ctgaaaatcc
     8341 taataattta aacctgcgct cagatatttc gtcaggagat gaaatcgaag aattgtctgt
     8401 tatctttgac aatatgttag acaaattgga gacacatact aagttgcaat cacgttttat
     8461 tagtgatgtc agccatgaat tacgaacacc ggttgcgatt attaaagggc atattggtct
     8521 cttacaacgt tggggtaaag atgacagtga tattcttgaa gaaagtttga cagcaacagc
     8581 gcatgaggct gaccgtatgg caatcatgat taatgatatg ttagacatga ttcgcgtaca
     8641 aggctcattt gagggacatc aaaatgatat gacagttttg gaagattcta ttgaaactgt
     8701 tgttggtaat tttagagttt taagagaaga ttttatcttt acatggcagt cagaaaatcc
     8761 aaaaacgata gcccgtattt ataaaaatca ttttgagcag gctttgatga ttcttattga
     8821 taatgctgtg aagtattccc gtaaagaaaa gaaaatcgcg attaaccttt cagtgactgg
     8881 caaacaagaa gctattgtta gagttcaaga taaaggcgaa ggaatttcta aagaagatat
     8941 tgaacatatc tttgaacgct tttatagaac ggataaatca cgtaatcgaa caagtactca
     9001 ggctggatta gggattggct tgtctattct caagcaaatt gtagatgggt atcatttaca
     9061 gatgaaggtt gaaagtgaat taaatgaagg ttcagtgttt atcttacata ttcctttggc
     9121 ccagtctaaa gagagttaga gtagcttaag gcattgttaa tgtgacaggt atagtatgta
     9181 atcattagat aatagtagca gtcttttgcc acaactggtt agaagctgat gctatttttt
     9241 tagcaatgat ggatgacatg aaagaaatac tgtcaatcgc gatgcctttt gttatccttg
     9301 ataatatggt aaaatagtgt attagattaa tttgatagaa ttggggtgtt tgcgtgcgtt
     9361 gtccaaaatg taattaccat aaatcgagtg ttgttgacag tagacaagct gaagacggca
     9421 acaccattcg tcgtcgaaga gaatgtgaac agtgtcatac tcgctttact acctttgagc
     9481 gtgttgaaga actcccttta ttagtcatca aaaaagatgg cacacgagag caattttcta
     9541 gagataaaat attaaatggg gttgtccaaa gtgcgcaaaa acgacctgtc tcgagcacag
     9601 atattgaaaa tgtcatttct cgtattgaac aagaagttcg aacaacctac gaaaatgaag
     9661 tgtcaagtac tgctattggt aatttagtga tggatgagtt ggccgaactt gatgaaatca
     9721 catatgtacg ctttgctagt gtctacaaga gcttcaagga cgttgatgaa atcgaagaac
     9781 ttttgcaaca aattacgaat cgcgtacgcg gaaagaaaaa acgtttaaat aatgatgaaa
     9841 ccaattgata cttttacata tctaaaacgc aacaaagtaa ctcttgattc ggtgacttta
     9901 atacagttgt actttccaat tattggaagt gacgcagtct ctatctatca atactttatt
     9961 cacttttttg acgatggttt acaacgtcat aaattcagcg atattttaaa tcacctacag
    10021 tttggtatga aacgttttga agatgctctt gccatattga cagcaatgga attagtgagt
    10081 gtgtatcagc tatcagatac atatctcatt acgttgcacc agccgcttag ccgtgacttg
    10141 ttttttcaac atccagctta ttctcgatta ttagaacaaa agattggaga ggtagctgtc
    10201 tctgagttgc aggtaactgt cccaagtcaa gcaagaaata tttctaagcg attttcggat
    10261 atttttgggg tgcaaggaga tttgacgaac gtacctcaaa agccacaaaa gaattttgac
    10321 ctttcaagtt tccagcaatt aatggttcgt gatgggttac aatttgaaga taatcaaaaa
    10381 gatatcatca gcctttacag tattgctgaa cagtatgata tgacgtggtt tgatacttat
    10441 caaatagcta aggcgacggc tgttaatggg aaaattcgac ctgaacgctt attggctaaa
    10501 aaaaatcaaa gcatgacaaa accaagcaaa gaaaattttt cacaggctga gcaaattatt
    10561 ttgcgagaag caaagcaaga cagtgcttta gtctttttgg aaaaaattaa aaaggctaga
    10621 cgtgcaacga ttactaagga tgaacgcatt ttattgcaaa cattggccaa aatgaatttt
    10681 cttgatgatg ttatcaatgt catggtgctt tataccttta ataagacaaa atctgctaat
    10741 ttacagaaga gttatgtctt aaaaatggcc aatgattttg cctaccaaaa ggtgtcaacg
    10801 gctgaagaag ctatagtggt tttgcgagcc ttcacggatc gtcaaagtcg tcggcaatca
    10861 aaagtaaaaa caagtcaaag caatgtgcct aagtggagca atcctgatta ccaagagaca
    10921 acaagtcaag aagagcaggc gaaactagat cagttcaaac aggctgcttt gaagaggtta
    10981 gaaaacctag gaaaaggggg tgactagatg gaaaagattg gagaaaccat ggcgaaattg
    11041 ggtcaaaaca ctcgtgttaa tagcgaccag ttgattcaaa ccattttagc ggatcctgaa
    11101 gtagcaagct tcatcagtca acatcactta tctcaagagc aaattaacct tagcttatct
    11161 aagttcaatc aatttttggt ggaacgccag aagtatcaac tcaaagatcc ctcttatatt
    11221 gctaagggct atcagcctat tctagctatg aatgagggct acgctgatgt gtcttatttg
    11281 gaaaccaaag aattggtaga agctcaaaaa caggcagcta tctctgaacg gattcaactg
    11341 gtcagtttgc caaaatccta tcgccatatt catttaccag atattgatgt taataatgcg
    11401 agccgtatgg aagctttctc tgctatttta gattttgtgg aacaataccc atcagcagag
    11461 caaaaaggct tatatttgta cggagatatg ggaattggca agtcttactt gttggctgct
    11521 atggcccatg aattgtctga gaaaaaaggt gtgtcaacga cccttctaca ttttccgagc
    11581 tttgccattg atgtaaaaaa tgccatttca aacggctctg ttaaagaaga aatcgatgcg
    11641 gtcaaaaatg taccagtgct cattttagat gatattggtg cagagcaagc cacttcttgg
    11701 gtccgtgatg aggtgttgca ggtgatttta caataccgta tgttagagga attgccaacc
    11761 ttctttacct ctaattacag ctttgcggat ttggagcgaa aatgggcaac catcaaagga
    11821 agtgacgaaa cttggcaggc caaacgtgtc atggaacgcg tgcgttattt ggctagagag
    11881 tttcatttag aaggggctaa ccgccgttaa gtttgagata gcaatcaaga agaatagcta
    11941 cacgtatgag tgagtgaaag aaaaggagaa tcatggtttt acctaccgtt gccattgtgg
    12001 gccgtccaaa tgtgggcaag tccaccttat ttaatcgaat cgcaggagag cgcatttcaa
    12061 ttgtagaaga cgttgaaggg gttactcgtg accgtattta tgctactggg gagtggctta
    12121 accgccaatt ctcattgatt gatacaggtg gtattgatga cgttgatgcc ccgtttatgg
    12181 agcaaatcaa gcaccaggct caaattgcta tggaagaagc ggacgttatt gtctttgtcg
    12241 tttctggtaa agaaggggtg accgacgctg acgaatatgt gtctaaaatt ctgtatcgaa
    12301 ccaatacccc agtcatttta gctgttaata aggttgataa tcctgaaatg cgtaatgaca
    12361 tttatgattt ttattcactt ggtttagggg atccctatcc agtttcttct gttcatggta
    12421 tcggaacagg ggatgtcttg gatgagatcg ttgaaaactt gccagtagaa gaggctgaag
    12481 aaaatgatga tattattcgc ttcagtttaa tcggtcgtcc taatgttggg aaatctagct
    12541 tgattaacgc tattttaggt gaggaccgtg ttatcgctag ccctgtcgca gggacaacac
    12601 gtgacgctat tgacacgcat tttacggatg ctgacggtca agaatttacc atgattgaca
    12661 cggctggaat gcgcaaatct ggcaagattt acgaaaatac agagaaatat tctgtcatgc
    12721 gtgccatgcg tgccattgac cgctccgatg tggtcttgat ggttatcaat gctgaagaag
    12781 gtatccgtga atacgacaag cgtatcgctg gctttgcaca cgaagctggt aaaggaatga
    12841 ttatcgtggt taacaaatgg gataccattg acaaggataa tcataccgtt gctaagtggg
    12901 aagccgatat tcgtgaccaa ttccaatttt tgacatacgc tccgattatt tttgtgtcag
    12961 ctttgacgaa gcagcgcctc aacaaattgc ctgacttgat taaacgtatc agtgagagtc
    13021 agaataaacg tatcccatct gctgtcctca atgatgttat catggatgct attgctatta
    13081 atccaacgcc aacggataag ggtaaacgtt tgaaaatttt ctatgccact caagtgtcag
    13141 taaagccacc aacatttgtc gtctttgtta acgaagaaga attgatgcac ttctcttatc
    13201 tacgcttctt ggaaaaccag attcgcgcag cctttacctt tgaagggaca ccgattcatc
    13261 tgattgctcg caaacggaaa taagaaatga acatcaacta aaatgctgac ctaagaaata
    13321 atctcatcat tgataaggac tgtgttgtgt atgttacagg agacagtcct ttttataata
    13381 cctttaaggg tgtagacgga agattagtag caaacaaaga aaaaggattt tgacaagaaa
    13441 tatcagtcgg tttttgctat aatgaaagga taagcaaaaa ggtggaaaaa tgatggctag
    13501 attaattcca ggacgagtaa ggaatgaagg tattaagctt tatgagcaag gtttagtctc
    13561 attccaagat gataataaag gcattcttca aatagaagtg gagacttatc aggttcaata
    13621 tggagcagat gatgaggata tcacttgtca atgcgacaca tttcatatga aacattattg
    13681 caagcatatt gcagcagtcg agtatttttt aaaaaatgat caaaaaggta agcttttttt
    13741 aaaacagtta acaaatcaaa caaaaatcaa agaaacaaca aagaaaatga catcttttgg
    13801 tagtctcttt ttagatagct tagccatgaa tgaagatgat tctgttaaat acaggctgtc
    13861 tgctcttggt agtcgaagcc ctttttcgtc agattactgg tggagtctga aaatcaatcg
    13921 tttaccagat gatcgttctt atgtgattcg agatattaaa ggctttttgc agcttattaa
    13981 aaaagaaggc ttttatcaga ttggaaaaaa ttattttgaa caactttcat ggctgcagtt
    14041 tgacccatcc agtcaagacc ttattgagtt tttatggcgc ttagcatcta atactgacaa
    14101 aggggacaac gagaacattt ttccaaatca tgcaaggcat ttgcgcttac ctagtggttt
    14161 ttttgaagaa ggtattcact atttgacgtc actttatgac tttacttttg aggggccttc
    14221 tcaaacttat catcatcttt ttgtccgttc tttggaagca gaggcaggcc tttatgagtt
    14281 taaagtggaa gtgcatcgca aatctattga attgcaaatt gctgaaaaaa atgtgcaata
    14341 cctctttgat aatgactatc ttctttatca agataccttt tatcacttga cgttaaagca
    14401 acgaaaaatg gttcaggcta ttcgtagtct gcccattgag gccgacttgg ctaaacatat
    14461 tcattttgat ttggatgatc atgcgaaatt agctgcaagc ttatcagatt ttaaacagat
    14521 cggtctagta gaggctccta aaagctttgc tattagagac tttgaggtga cttttcaatt
    14581 tgatttgtta aatcgagatg aaatcagttg tcagcttatg tttgattatg gcaattacca
    14641 agttagtgac aaagcaagtt tagaagcact tccttttgct agtcatttaa aaaaagaaga
    14701 aaaaatcaat cgttctttac ttgcttttgg cttctcgcca caattttact caaaaaagcg
    14761 actaacaagt gcaaaagagc tctatacttt ttttgaagaa acagttccat gttttgagcg
    14821 cttaggtaat gttgcgttga gtacagctat ccaagcatta caagtgaaag aaatgcccaa
    14881 gatcgctatt agacgcaatc agggattact agatatttcg tttgattttt caaccattat
    14941 tgaaaatgat attgaccaag ctgttacagc tctttttcaa aataatcctt attttgtgag
    15001 tcaaacaggt caattagtgg tttttgatga tgaaactcaa aaagttagca aaagtttaca
    15061 agaattaaga gcaagacagc taaaaaatgg tcacttgcaa ctggatggca ttagagctct
    15121 acaagtatcc aaactttttg aaggcatgac atctgttcat ttttcaaagg aattagaaga
    15181 gttagcctat catttgcagc atcctgaaac tttttcaata aaaccgttac cagttaaggc
    15241 tcaaatgcga gattatcaac gcaacggtgt tcagtggtta tcaatgctca atcattatgg
    15301 ctttggtggc attttagcag atgacatggg acttggaaaa actctccaga cacttgcttt
    15361 tttagctagt cacctgaaat cagatagtaa agtgctcatt ttatctccat ctagtcttat
    15421 ctataattgg tttgatgaat gtcaaaaatt cacacctcag ctagatgttg tagtttctta
    15481 cggacttaaa caaatcagag atcaaatcat cgaagaaggt catcaaataa ccataaccag
    15541 ctattcctcc tttagacagg attttgagac ctatcaagcg tttcactacg attatcttat
    15601 cttagatgaa gctcaagtga taaaaaatgc gcaaactaag atttcacact gtttacgtgc
    15661 gtttaataca gccaattgtt ttgcgctttc gggcactcct attgaaaata aaatgcttga
    15721 aatttggtcc attttccaaa ttgttttgcc agggttgcta ccgactaaaa aagagttttt
    15781 aaaattaaca gctgagcaag tatcgcgcta tatcaaaccc tttgtgatgc gtcgtaaaaa
    15841 agaagatgtc ctaccagaat tacctgattt aattgaaact aattattcaa acgagatgac
    15901 agatgaacaa aaagctattt acttagcgca gttaaggcag atgaaagatc aaattcgaaa
    15961 ttctagtgat gtggatatta gccgtcaaaa aattgagatt ttatctggta tcactcgatt
    16021 gaggcaaatc tgtgacactc caagtctctt tatggattac caaggcaaaa gtggtaagct
    16081 agatagtttg cgaatcttat tgacacaaat taaagaaaat ggtcatcggg ctttgatttt
    16141 ttctcaattt agagggatgc tggacttggc caagcaagag atgactgctc taggattgac
    16201 ctcttatcaa atgaccggat ctacccctgc caatgaacgt caagaaatga ctagagcctt
    16261 taataacggt tccaaggatg cttttttgat ttccctcaag gcaggtggag ttggaatcaa
    16321 ccttacggga gcagacacag tgattttaat cgatttatgg tggaatcctg ctgttgaaat
    16381 gcaggcaatc agtcgcgcct accgtattgg tcaaaaagaa aacgttgaag tatatcgctt
    16441 aatcactcga gggacgattg aagaaaagat tttagagctt caagaaagta agcgcaattt
    16501 ggtgactaca gttttggatg gcaatgaaaa ccgagcaagt atgtccattg aagaaataaa
    16561 agaaattttg gggctaaaca ctcattaatc ttccttgatt ttagtgacat taaaaaccct
    16621 ttaaagaaga tgacaccaaa agcaccttat ataacctcgt taaaacgctt ctttttgaaa
    16681 tatctttatt gatatagcga ttgtcatttg ctagtaatga ttaaaacatt tagaaaaaga
    16741 caagtcatag aatcatcaag gaatgctttg aaaaataaca gtatttaagt tataatagag
    16801 gatgctacaa gaagggagaa tcaaaaaagg atggtaaaaa atcagtttcc tttagttgca
    16861 gatggcattg ctattagtga tccagcaaag caaatggctc tgtatgaaaa tgaagatctc
    16921 attaccaaca tccgtggcta ttaccaggac aaggagtatg atgatattgc tagaaatgag
    16981 gagtttactg ctaaagcaac ttctcggcag gccccttcta gtaagcgctt ttgtagcaat
    17041 gatgaaaaac accattatgt caaagaggcg cgtcaaaaag caaagcaaga tctcaaggaa
    17101 aaaagacagg cttatcttgc caaagaaatg gcctatgttc ctaaacaggt ttctaaaaag
    17161 caacagcctg cggattcttc tccttctcaa aagcaagcaa caacagaaat gagtcgtttt
    17221 acaaaaaagc ttcatcaaga caactatatt ttagctgagt tgccaaaaga atataaagag
    17281 ccaaaaaatc ttcctcaaca aggaactaca aaaaaaaata attacgattt tttaaaatcc
    17341 agtcaaattt acaataataa agaaatgaga caacaacgag aaaaaacaat tgcgcaagag
    17401 cttaatctta gtaggtttga ggatcttcct taataaatct actcagcgta tgcagatgac
    17461 aaaggagtta agatgtcaaa aacgtatcat tttatcggaa ttaaagggtc aggaatgagt
    17521 gccttggccc ttatgttgca tcaaatgggg cataaggtgc aaggtagtga tgttgaaaaa
    17581 tactatttca ctcaaagagg attggaacaa gcgggcatca ctatcttacc ttttagcgag
    17641 gacaacatta cgccagatat ggaacttatc gttgggaatg cctttcgtga aaacaacaaa
    17701 gaagtggcct atgctttgag acaccagatt cctttcaaac gttatcatga ctttttaggt
    17761 gattttatga aatcatttat cagttttgca gtagcaggtg ctcatggtaa aacttctaca
    17821 acgggtttat tgtcacatgt cttgaaaaat atcacagaca catcttattt aattggtgat
    17881 ggtactgggc gtggatctgc taatgcacag tattttgttt ttgaatcaga cgaatacgaa
    17941 cgccatttta tgccttatca cccagaatac tctatcatta ctaatattga ttttgaccat
    18001 cctgattatt tcacaggaat tgctgatgtg cgaaacgctt tcaacgatta tgctaagcag
    18061 gtcaagaaag ctttgtttgt ttatggtgaa gatgacgaac taaaaaagat cgaagcacct
    18121 gcacctattt actattatgg ttttgaagag ggcaatgatt ttatcgctta cgacattacg
    18181 cgtactacga acggatcgga ctttaaggta aaacaccaag gagaggtcat tggtcagttt
    18241 cacgtacctg cttatggaaa acataacatt ttaaacgcta cagcagtaat tgcaaacttg
    18301 tttgtagccg gcattgatac ggctctagtg gcagaccatc ttaaaacttt ttcaggtgtg
    18361 aaacgtcgtt ttacagagaa aattatcaat gacactatta ttattgatga ctttgctcat
    18421 catccaaccg aaattgtggc aacaattgat gcggctagac aaaaataccc aagtaaagaa
    18481 attgtagcaa tatttcagcc acatactttt actcgcacta ttgccttatt agaggatttt
    18541 gcttgtgctt taaatgaagc tgacagtgtt tatttagccc agatttatgg ttctgcacgt
    18601 gaagtagata aaggtgaagt taaggttgaa gatttggctg ctaagattat caaaccatca
    18661 caagtagtaa cggtggaaaa tgtctctcct cttcttgatc acgataatgc tgtttatgtt
    18721 tttatgggag ctggagatat tcagctatat gaacattctt ttgaggaatt acttgcaaat
    18781 ttaactaaaa ataaccaata acatgtcctg ccttaggcag gttttctcat tctaaaggag
    18841 tttgatatgt tgattagaca ggttcaagga tccgatttgg aagttattgc taccattgaa
    18901 agtgacaatt tttcaccaca agaagcaacg acaagagcag ttcttgaaga gcgcatacgg
    18961 ctgataccag atactttttt agtggcactt atcgatcagg aaattgttgg ctatatcgaa
    19021 ggtccagttg tcactactcc tattttggag gattctttgt tccacggggt gactaaaaat
    19081 cctaaaactg gaggctatat tgctattact agtttgtcca tagctaaaca ttttcagcaa
    19141 caaggggttg ggacagcttt gttggcggca ctaaaagatt tagtagtagc gcagcaaaga
    19201 acaggtctta ttttgacttg tcatgattac ttgatttcct attatgaaat gaatgggttt
    19261 attaaccaag gaatttcaga gtctcaacat ggtggaaccc tttggtacca aatgatttgg
    19321 aaactttaga atcacagctg attcaactgt tggtttgtta aaaataagta acaaatgcat
    19381 catttaattg caattaggat acttttaagt tataatggcg gttgattata tttaggagga
    19441 ttggctttga ccgattttaa ggataaagac caacaagatc agcagcgaag ctttaaagag
    19501 cagattcttg ctgagttgga aaaagcaaat caaatcagaa aagaaaaaga ggaagaactt
    19561 tttcaaaaag agttggaagc taaagaagca gctaggagaa cggcccagct atatgctgaa
    19621 tataaaagac aagatgcttt tcaaaaagag tctatagcac ataacaataa gacagctaaa
    19681 cactttcaag ctataaaagg tgcggtaatg acttcagaag cgcttaaacc gactttactt
    19741 tctgaaaaag aaaactcatc tttaaaaacg acaaataaga gagtcgtgca ggcaaatgag
    19801 cttcaagaga ctgcctctaa agaatctcaa gtaccgttaa ctattgagaa aggtcattca
    19861 gtgagacgaa aattaagcaa atgccaacag actgagcgag ctgctaaaaa gatttcaacc
    19921 gttttgatta gttctattat tataaccctt ttggctgtta ctctagcagg agcaggctat
    19981 gtttatagtg ctttaaatcc tgttgataaa aatagtgatg cctttgttca agttgagata
    20041 ccatctgggt caggcaataa attgattggt caaattcttc aaaaaaaagg tttaatcaag
    20101 aatagcactg tttttagttt ttatacaaaa tttaaaaact ttacaaattt tcagagcggg
    20161 tattacaatc tgcaaaaaag tatgagtcta gaagaaattg ctagtgcttt acaagaaggt
    20221 ggtacagcag aacctaccaa gccatctctt gggaagatct tgattccaga aggatacacg
    20281 attaaacaaa tagctaaagc tgttgagcat aatagcaagg gaaagaccaa aaaagctaaa
    20341 acacctttta acgagaagga ttttttggat ttagtcacag atgaggcttt tattcaagat
    20401 atggtaaaaa gatatccaaa attattagca actatcccaa ctaaagaaaa agctatttac
    20461 cgtttggaag gttacctttt cccagcaacc tataactatt acaaagaaac taccatgaga
    20521 gaacttgtag aggacatgct ggcagctatg gatgctactt tggtacccta ttatgataaa
    20581 attgctgcta gtggtaagac agtcaacgag gtattgacct tggcctcttt ggttgaaaaa
    20641 gaaggttcaa cagacgatga cagacgtcaa attgcaagtg tcttttataa ccgccttaat
    20701 agcggaatgg cactacaatc taatatagct attttgtatg cgatggggaa acttggtgag
    20761 aaaacaacct tggctgagga tgctactatt gacaccacca ttaattctcc ttataatatt
    20821 tataccaata caggtctgat gcctggtcca gttgctagct cgggggtttc tgcaattgaa
    20881 gcaaccctaa atccagcctc aacggattat ttatactttg tggccaatgt ccatactggt
    20941 gaagtttact atgcaaaaac atttgaagaa cactctgcaa atgttgaaaa atatgtgaat
    21001 agtcaaattc agtaaacaca aacatggtgc ttaagcacca tgtttgtgtt tctgattcgt
    21061 tcaaaaaaga aaagagagaa aacaattatg gcagaaaaaa cgtatccgat gaccctaacg
    21121 gaaaaagaac aacttgaaaa agaacttgaa gaattaaaac ttgtgcgtcg tccagaaata
    21181 gtggagcgta ttaaaattgc acgttcgtat ggagatcttt cagagaactc tgaatacgat
    21241 gccgcaaaag atgagcaagc ttttgttgaa ggtcaaattt caacgcttga aactaagatt
    21301 cgctatgctg aaatcattga cagtgatgct gttgcaaaag atgaagtcgc tatcggaaaa
    21361 acagttatcg ttcaagaagt tggaacaaca gataaagata cctatcatat tgtaggtgct
    21421 gctggagcag atatcttctc aggaaaaatt tcaaatgaaa gcccgattgc tcaagctttg
    21481 attggtaaaa aaacaggtga caaggttaga attgaatcac cagcagctac ttatgatgtt
    21541 gaaatcatca gcgttgaaaa gacaaattaa tcagatgaag ccattatttg cctaaccact
    21601 aagtgttttg gttgctaatg gcttttctag tatcttcaaa tgaggttgac tgttaggaag
    21661 gtcaagtatt aatcgcattg attatgagcc aagaggacta tagatcaaag atcgttttcg
    21721 atggttattt aatgccaaaa gaaaagacca gcaccttaat gtactgaccc caaaaagttg
    21781 gacactatat tttaaggaag tgtatgatct aaggaaactg acactaatga ttgaccgttt
    21841 tgcaagactt tattaatgat ttcttgcttt attttaaatg aataagtctg atacgtttcc
    21901 ttccttaaca ctatcgactc catactgacc catcagtcaa acggtatatc tcaaacgact
    21961 acggtttact ccaaattgat tggctagttg aggccaagaa acacctgatt ttttttaatg
    22021 ctaaatttct agcttatctt catagcttaa tttcatacaa aaacacccca atcgttagat
    22081 ttttttgata tgtccccttt cactagatga gtccagtaaa agggggcata tcgttttttg
    22141 tctaactttt ggggtgcagt tcataattgt gctaggtttt ttgtctttct taacgctttc
    22201 gctgttttcc agcattacga ttggatttta tttttttagg caagttagcc tgttccatgt
    22261 tttgtgaagg cgtaacgtcc ttacgagaag aagttgattg gtatgcttta ggcgggtttt
    22321 tagcgtattc ttctttaatt tgcttatgca atcgaggttt taagaggtag gttgtgatta
    22381 actgttgaat aatactaaag aaaccaccaa ctagccagta aagaccaaca ccagcaggga
    22441 gtgagaagga catgaagatc atcatgatag gcatggtgta catcatcgtc ttcatttgct
    22501 cacgttgttc ttctgaaacg gccatcattg ataaccatga ttggaagaag taaagagcag
    22561 cgataattgc tgttaacact aaactacggc taccaagatc aatacccata aaggtgcttg
    22621 ttgatactcc tttagtgtat tgagcggcaa aatacatggc agaaaagaat ggcatctgga
    22681 tgagaagagg tagacatcca atacctccaa gaggattaat cccatgagca cgctgagcag
    22741 ccattaattc tgtttgggca gccatttttt cttcctgact acttgcctgt ttgatacgtt
    22801 tgttgattgg ttcaaaaaca ggtttcaaga aggccatttt ctcagattga taacttgctt
    22861 tccaagattg atatagacct agtggtaaga taagtgttct aacaataatg gttacgatga
    22921 tgatagccag tccataacct agtccagcat tgtttgcaaa gtaatcgata aagtatgaca
    22981 tgggttttcc aagaaattcc caaatcatac ctttgggatt tccgtgagcg tctcttccca
    23041 cacagcctgt caaggtgaat agaattgaca gtgctagtcc tgaaaagagg atgcgattta
    23101 atgttagttt caatgtgttt atcctttaat tttaatatac ttatctattt tacagttttt
    23161 ttcagaaatt cacaatagtt ctgaaggccg atttttactt gcctatttga aagtcctgaa
    23221 agtcttcaaa attagccatg gtgacatcca cataagtgac ttttgcccat ttggatggtc
    23281 ctttacgaac ttcttgaata aatgtggcta ttttatctga atcttttgat tgggccagga
    23341 tttcaacggt cccatcgttg ttattccaga cacgaccata aatatctcct atatctagag
    23401 ctaaagtatg ggtagcgtat cgaaaaccaa caccttgtac acgtccagaa acaattaaac
    23461 gtactttttg cataagaagg gcctccttgc ttttattata gcacatactt agcaggaaat
    23521 ctctttagct aattgtctac ttcctgtcac ttttactaaa gacaagaata caaaaatgag
    23581 atagttagta gtactaacag taaaagaggt ttgtctattt taaaaatagt atcaaaaaaa
    23641 ggtcttttag gtttaaaaca ttgaactgcc cccaaattga ccatctaaga agttgatgct
    23701 ttcaaatgct gtcgcgtatg gtataatagg tgcatggtta ttacatcaaa aacaaatcaa
    23761 ctaattaagc aaacaaaaaa attattgcaa aaaaagcatc gaaaacagtc ctatttgatt
    23821 gagggctggc acctttttga agaagcccaa aaatcaggac aagtttttcg ccacatcttt
    23881 gttttagagg aaatggtgga gcgtctagca ggtgagcaag aactcgttat tgttagccca
    23941 caagtgctca aggagttgac cgactctcct agtccacaag gcattgttgc tgaggtggag
    24001 atacctaagt tagcctttcc atcagattac aaagggaaat atttggtttt agaggacgtc
    24061 caagacccag gaaatcttgg gaccatcatt cgtacagcag acgctgcacg gtttgatggg
    24121 gtctttcttt ctgaaaaatc agcagatatt tacaaccaaa aaaccctacg ttccatgcaa
    24181 ggtagccatt ttcatttacc aatttggcga acagatgtct atcagctttg tcgagagctc
    24241 caagagtata aaactcccat cctagcaaca actctgtcaa agaaatctgt tgactataaa
    24301 agcctcacac atcatgaaag gttggctttg gtgttgggaa atgaaggcca gggcattagt
    24361 gctgaaatgg cagccctagc agaccaactg gttcatatta caatgcctgg tcaggcggaa
    24421 agtttgaatg ttgccgtagc agcaggaatc ctcattttca gcttgattta agctaatatg
    24481 atataataac caagtggggt gattatgtta tgcattatac agaagataaa gaatatatgg
    24541 aacacgtcgg tcatttgatc gctcatcctc gctttcaaaa attgagtcat attgttcagc
    24601 accaacattc aacgcgtctt gaacattcta tcaatgtttc ttattccagt tataaattag
    24661 ccaagcgatt tggttgggat gctaaaagta cagccagagg gggcttactt catgatttct
    24721 tttattatga ttggcgcgtg accaagttta ataagggtca tgcctgggtt catcctcgta
    24781 ttgctgtacg aaatgcgaaa aagttaacag aactcaataa aaaagaagag gatatcattc
    24841 taaaacacat gtggggagcg accattgctt ttccgcgtta caaggaaagt tatattgtga
    24901 caatggtaga taaatactgg gctgtcaagg aagcagtgac acctttaaga caaaaatggt
    24961 ctaatcgacg gtttcttcgc cgcaagaccc tccaaagtca taatcgttaa gtaaaggagt
    25021 tattatgaac gatcacgtta tttatacaca atcagatgtg ggattaaatc agttttttgc
    25081 taaaatttat agtctagtgg gaatgggagt gggtttatct gcttttgttt cttatttgat
    25141 gctttatcca tttagagaaa atttaatctc tattcttgtt aatcagccga tgatttacta
    25201 tggtgctgcg attattgaac ttattttagt ttttgtagcc agtggtgcag cacgaaaaaa
    25261 cacaccagct gcattgccca tttttcttat ctattctgcg ctaaatggct ttaccctaag
    25321 ctttattatt gtggcatacg ctcaaacgac agtttttcaa gcatttcttt cttcagcagc
    25381 tgtgtttttt gccatgtcaa tcattggtgt caagactaaa cgggatatgt caggtcttag
    25441 aaaggctatg tttgctgctt tgattggtgt tgttgtggct agtctgatta atctttttat
    25501 tggtagtggg atgatgagtt atgtcattag tgtgatttcc gtgctaattt tctcaggtct
    25561 catcgcatca gataatcaaa tgattaagcg cgtttatcaa gcaacaaatg gccaggttgg
    25621 tgatggctgg gctgttgcta tggccttaag cttgtattta gattttatta acttatttat
    25681 cagccttctt cgtatttttg gaagaaatga ttaacattaa aaagtgagta taactactca
    25741 ctttttaatg ttaacaggat aagtaaactg taaggaagaa attcgagata gatataagat
    25801 gaggctgcta aaagacctag tgttaatttg taaactcttt ctttttttgg tatactatta
    25861 aggattaaat acgaggagaa tatagataga tatgtcaaca gctatttgga ttttattact
    25921 tattgttgcc cttggggtag gtgtttttgg tgggattttt attgcccgta aacaaattga
    25981 aaaagaaatt ggtgaacacc cacgtttaac accagaagct atccgtgaaa tgatgagcca
    26041 gatggggcaa aaaccaagtg aagcaaaaat ccaacaaact tatcgtaata tcatcaaaca
    26101 atcaaaagca gccgtatcca aaggtaaaaa ataaaagcta attgttatag gggaaacctt
    26161 tgtgatagtt agaagtgaac agtctttgat ctcaatgttc agtagcactt gtcttatcag
    26221 ttagatttgt caactgttca gggtttaaaa agaaactcag ttggctattt ccaactgagt
    26281 ttttcatatc gtcagtaagg aagtaaacat aatggataca agaccaattg ggtttttaga
    26341 ttctggtgtg ggaggtctga ccgtcgtttg tgaattgatt cgtcagctcc ctcatgagaa
    26401 gattgtatat attggtgatt cagcaagagc cccctatggt cctagaccca aaaaacaaat
    26461 taaggagtat acttgggagc tagtcaattt tttgctgact caaaatgtta aaatgattgt
    26521 ttttgcatgc aataccgcaa cagcggtggc ttgggaagaa gtaaaagcag ctttagatat
    26581 tcctgtttta ggggttgtct taccgggggc aagcgcagct attaaatcaa cgacaaaagg
    26641 ccaggttggg gtcatcggaa ccccaatgac agtggcttca gacatttatc gcaaaaaaat
    26701 ccagctatta gcaccatctg ttcaagtaag gagtcttgct tgcccgaagt ttgtaccgat
    26761 tgtggaatca aatgagatgt gttcgagtat agctaaaaaa atagtttatg acagtctatc
    26821 accattagtc ggtaaaatag atacccttgt actaggatgt actcactatc ccttgttacg
    26881 accaattatc caaaatgtta tggggccatc tgttaagctg attgacagtg gagcagaatg
    26941 cgtccgagat atctctgtct tattaaacta ttttgacatt aacggtaatt atcatcaaaa
    27001 agctgtcaaa caccgctttt ttacaacagc aaatcctgag atttttcaag aaattgcctc
    27061 gatttggctg aaacaaaaaa taaatgtgga gcatgtcacc ttatgagtga aaaaatttac
    27121 gaatacaaag atgaaaataa ctggtttatc ggaaagatga ctggtcataa tttaatatcg
    27181 ggctggggag tcaaacacac gacaatcaaa aaaatagatg accttttaga cggtattgcc
    27241 gcaacgttag attgggaaaa tcctaaaggt tacgatgttt cggtggtgcg ttatcagtct
    27301 cctttatctc tcatcacctt tattatcgac atgataaatc aagagaccca gcgtaagatt
    27361 aaggtaactc cccatgcagg cacgatttta ttaatggaaa atgcgaaact gcttgcagtt
    27421 tatctcccag aaggtggagt ttcaacggct acattttttg cgactagtga acagggattt
    27481 ggggatatta ttttaatcgc tacacgaaac gagggaaaaa ccaaagagtt ccgcaatctg
    27541 tttggccagc taggttatcg tgtggaaaat ctcaatgatt atccagaatt gccagaagta
    27601 gcagaaactg gtactacttt tgaagaaaat gctcgcttga aagcagaaac gatttcacgc
    27661 ctcacaggaa aaatggtatt agcagacgat tcaggactaa aagttgatgc cttgggtggt
    27721 ttacctgggg tttggtcagc tcgtttctca ggaccagatg ccacagatgc caagaataat
    27781 gccaaactct tacacgaatt agctatggtg tttgaccaaa agaagcgctc agctcaattt
    27841 catacgactt tggtagtggc tgctcccaat aaagatagtt tggttgtgga agccgagtgg
    27901 ccaggctata ttgctacgca gcctaaggga gaaaatggtt ttgggtatga ccctgtcttt
    27961 atcgtcggag agactgggcg tcatgctgca gaattagagg ctgaccaaaa gaatcagttg
    28021 tcgcatagag gtcaagcagt tcgaaaatta atggaggtct ttccagcatg gcaagcaaaa
    28081 caatcatagt aatgagtgac tctcatggtg accgagatat cgttcaagcc attaaagaca
    28141 agtatcttgg tcaagttgat gctattttcc ataatgggga ttctgaatta aacagctcag
    28201 atcctatttg ggctggtatt tatgtcgttg gcggtaattg tgactatgat acaggttacc
    28261 ctgatcgttt agtaactcaa ttaggcacag ttacgattgc ccagacacat ggtcacttgt
    28321 accatattaa tttcacttgg gataaactgg actactttgc tcaagaagta gcagcagata
    28381 tttgtctata tggacaccta caccgtccag ctgcttggca agttgggcaa accctcttta
    28441 tgaatcccgg atcagtaaca caacctcgcg gagaaattaa cgagaaatta tatgctcgtg
    28501 ttgaactaac tgatactcaa attaaagttg attactttac aagagatcat aaactttacc
    28561 catcactgtc taaggaattt aaacgatgat cgcaaaagaa tttgaaacgt ttttaatgag
    28621 tcatttagat aattatctta tcccggaaca agacttggct atttttatcg acacacataa
    28681 tgcagaccat gtgatgttac ttttggtgag caatggtttt tctagagttc ctgttatcac
    28741 acgggagaaa aaatatgtgg gaaccattag catctcagat attatgatgt accaatctaa
    28801 aaggcagctg acagattggg aaatgagtca aacagatatt ggcgagatgg ttaataccaa
    28861 aattgaaacc attagcatta cttccagcct aacagaaatt atgcacaagt taattgattt
    28921 cccattctta ccggttgtag atagagcgaa tcgctttgtt gggattatta cgcgaaaatc
    28981 tatattaaag gctgtcaaca gtcttttaca tgattttaca gatgattaca cgattataaa
    29041 aaaatgaaga gttatattga accttttatt gctagcaagg ctttatctca aaatagtcaa
    29101 aaagcttatc gatacgattt gcaacagttt tgtcaactga ttggtgaacg tgtcaatcaa
    29161 gacaaactat tactttatca aaatagtata gctaacctca gtttatctgc aaaaaaacgc
    29221 aaattatcaa cagctaatca attcttatac tacttgtatc aaataaagta tttaaatagc
    29281 tattttcgat taacagacac catgaaagtg atgcggactg agaagcagca agctgctatt
    29341 attaatactg atattttcta tcaaaaaacc ccttttgtgt gggggcaatt aatcagctta
    29401 ttaatattgg agctgggttt aactccgagt gaagtagctg gtattgaagt agctaacttg
    29461 gatttaaatt ttcaaatgtt gacgctaaag actaaaaaag gtgtgcgtgt attacctttg
    29521 tcgcaaatac taatcccttt tttagaacaa caactcgttg gcaaagaagc ctatcttttt
    29581 gaacatcgag gcatcccttt ttcaagacaa tggtttttta atcacctaaa aacctttgtt
    29641 cgaagtattg gttatgaagg attaactgct caaaaattac gagagcaatt tattttgaaa
    29701 gaaaaactag ctggtaaatc gataatagaa cttagcgata ttcttgggct gaaaagccct
    29761 gtgaccttag aaaaatacta caaatcataa tggatataaa acttaaagat tttgaaggtc
    29821 ctcttgattt actcttgcac ttggtatcac agtacaaagt tgacatctac gaggttccta
    29881 ttgttgaggt tattgagcag taccttaatt atattgaaac cttacaggta atgaaacttg
    29941 aagtggctgg tgactacatg ctgatggcaa gtcagctcat gttaatcaaa agtagaaggc
    30001 tattaccaaa ggtggtagaa cacatcgaag aagaagattt agaacaagat ctgttagaaa
    30061 agatcgaaga atatagtcgc tttaaagcag ttagtcaagc gttagcgaag caacatgacc
    30121 aaagggcaaa atggtattca aaacctaaac aagaattaat ttttgaagat gctatcttac
    30181 aagaagataa aacggtgatg gatctatttc tagctttttc aaacataatg gcagctaaaa
    30241 gagcagtttt aaaaaccaac catacagtca tcgagcgtga tgattataag attgaagaca
    30301 tgatggcttc tatcaaacag cgactggaaa aagaaaacgt tattagctta tcagcgattt
    30361 ttgaggaatg ccaaacatta aatgaagtta tcagtatatt tttagctagt ctagaattga
    30421 ttaagcttca cgtggtattt gtagagcagc tctctaattt tggggctatc atactacgaa
    30481 aggagaagaa atgacgtatt tgtcacagat agaagcgctg ctatttgttg caggtgaaga
    30541 agggttaagt ttgcgacatc tagcgtctat gttatcatta acgccaacag ctcttcaaca
    30601 gcaattagaa aaactctctc aaaagtatga aaaagatcaa cattctagtc tttgtttgat
    30661 agaaacagct aatacctaca ggctagtaac taaagaaggt tttgcagaac tcttgcgtgc
    30721 ttatgccaaa acaccaatga accaaagtct atctcgtgcg agtttagagg tcttgtctat
    30781 tgttgcatac aaacaaccta ttacacgaat agaaattgat gacattcgag gggtaaactc
    30841 cagtggagct ttgagtaaat tattggcatt tgatctcatt agagaagctg gcaaaaaaga
    30901 tgtggttggg cgtcctcatt tgtatgcgac aacagattat tttctggact atatgggaat
    30961 taatcattta gacgaattga ttgaagtatc tgccgttgaa ccagcagatg aagagattgc
    31021 tctttttagg acacaagact gagttttgct tgtcatcaaa tagcaaatgg cgtttacaaa
    31081 aggatttgtt ttaaggcgtt ttagttgaaa aaaagcctta aactagggac aacaaaaagt
    31141 tgctcaaaag aaagaagaat ataatgcgaa ttaacaaata cattgcccat gcgggtattg
    31201 ccagtcgacg taaggctgaa gaattgatta agcaaggctt agtaacctta aatggtcagg
    31261 ttattacgga tttagcaacc actgtaaaat cgggagacgt ggttgaaata gaaggaagtc
    31321 ctatttacaa cgaggaaaag gtttactatt tgcttaataa acctcgtggc gctatctcaa
    31381 gtgtgtcaga tgacaaaggc cgtaaaacgg tactggattt actgcctcag gttaaagaac
    31441 gcatataccc tgttggacga ttggattggg acacatcagg ggtccttatt ttaacgaatg
    31501 atggtgattt tacagatact atgattcatc ctagaaatga aatagacaag gtttatctgg
    31561 cgcgtgtcaa aggaattgca acgaaagaaa atcttcgtcc cttaactcga ggaattgtta
    31621 ttgatggtaa aaagaccaaa ccagctcgct acaatattgt tcgtgtagaa gctgataaga
    31681 atcgatcgat cgtagaattg actatccatg aagggcgaaa ccatcaggtt aaaaaaatgt
    31741 ttgagtctgt ggggcttttg gttgataaat tatctcgtac acgttttggg accgtcgact
    31801 taaagggact aagaccagga gaagcaagac gcttaaataa aaaagaaata agtcaactgc
    31861 ataacttagc taatacgaaa aaatgatgaa aaaactatta atagtatctg ttaaagctta
    31921 tcaaaaatac atttctcctt tatcgcctcc tagttgtcgc tacaagccaa cctgttcagc
    31981 ttatatgtta actgctattg aaaaacatgg tactaaggga atactaatgg ggatagcaag
    32041 aatattaaga tgtcaccctt ttgttgctgg tggtgtcgat cctgttccag aagattttag
    32101 cctaatgaga aataaaaaca cgtctaaaaa cgctgaaaag gcatgacttt atcaaaaaat
    32161 ggcttgacat tgatagctga agtgttataa tggaaaacaa gcattcgttg gtttaaatca
    32221 aacctgttat gatttaagtt agcgagtcac catcaaccac attgtttgct gagcatgact
    32281 ccgagcagtg tggtttttta aattaaaaag agtaaatgag attatgacga caaaagaact
    32341 tatcaacaaa aacgacaaag taaaaaaggc tcgcaatcat attgtcctgt ttcaacccca
    32401 aattccacaa aatactggta atattgctag aacatgtgct gcaactaatg cacctttaca
    32461 cattattaaa cccatgggat ttcctattga tgaccgcaaa atgaagcgtg ccggcttgga
    32521 ttactgggac aagttagaac tgcattttta tgatcattta gaacagttta tcaatcaatg
    32581 tcacggacag cttcacctga ttagcaagtt tgcagttaat aattattctc aagctactta
    32641 tgctgatggc gattcccatt atttcttgtt tggacgagaa gatacaggcc tgccagaaga
    32701 ttttatgcga gaacatgctg aaaaagcact tcgtattccg atgaatgatg agcatgtacg
    32761 gagtttaaat gtctcaaata cggtttgtat ggtgatttat gaagccctta gacaacaggg
    32821 ctttcaaggg ttagagttaa agcatactta cgaacacgat aaactaaaat aatggacttt
    32881 ttaaaagcgt cagtttttgg caacatgcgt tgtcagtagc tgacgctttt aaaaatttag
    32941 tcaaagctat tgctatctag gtttaaatct gctatgctag aagtgtcttc agggcagggt
    33001 gtgattcccg accggcggtg actaggtaac tagaagtccg cgagcgcaag ctgatgtggt
    33061 gtaactccac aaccgacagt atagtctgga tgagagaaga ccgggctttt tgtgtaggct
    33121 tattttagct acacaataac gacggaactt ctttcaattt gaaaaaattg gaggaatttt
    33181 ttaatgtcaa aaacacataa aatgattatg attggtatac tttctgcgat atcatttcta
    33241 ttgatgctag ttagctttgc cattattcca ggcgcagctt ttttaaaaat tgaatttagt
    33301 attattcctg tcttatttgg tttaatgatt atggacttaa agagtgctta cttgattttg
    33361 ttattgaggt ccttattgaa actctttttg aacaatcgtg gggttaatga ttttattggt
    33421 ctcccaatga atattatcgc tatcgcttta tttgtgacgg cttttgcctt agtttggaac
    33481 cgtcaaaaaa cgcttagtca atatgtattt gctagcttac taggcacagg gttattaacg
    33541 tttggcatgg ttgttctcaa ttatactttt gccattcctt tatatgctat atttgcaaat
    33601 attgatatca gagcttatat tggtgttact aagtatatga tgactatggt tattccgttt
    33661 aatcttgttg aggggttgat atttgcaatt accttttatt ttgtgtatat tgcaagtaaa
    33721 ccaattttag aaagatactt acactaatat gatgacaaac aaacaaactc actttttaat
    33781 agcttctttt gcattgctaa tctttgttat aataggctat acggtcaaat tttttcctga
    33841 acgtttggca cttctagata atactattca agcagagatt agaggcaacc ttcctatagt
    33901 gctgacgcaa ttctttaggg gtgttactgt atttggaaat gtcatgacac aagttttgtt
    33961 agttattgtg tcggtcctag ttttattctt tatgaagtgg aaaattgaag ccttgtttat
    34021 cttgtcaaat ggtgccattg cagcattttt gattacgact ctcaagctct tttaccaaag
    34081 accaagacct gctattgagc atttggttta tgctggtggc tattcgtttc ccagtggcca
    34141 tgcgatgggt agcatgctga tttttggtag cctattgatt atttgttatc agaggctaca
    34201 ttcaaaacta ttacaatttg tgactagcat gatctttata atactaattt tattaattgg
    34261 gttatctcgt atttatctag gagtacacta cccaagtgat attttagcag gctttgtatt
    34321 aggatttggt attttgcact ttatttatcc tttttataag caaaaacgat ttgaatggcg
    34381 atttcttttg aaacaagact aatttttctt gagaagacat aggcttattt aaatcattta
    34441 gaataacatt ggcaagcatc acccccttga ttgccagtgt tattttagtt ttagttagat
    34501 gatgtgagct gatgattagt aaatatgttt agataaaaaa cgattaaagt gctatgtaac
    34561 gtcagaaaag acgtgatttt tgttgatctg taatcattaa gtaagctgat gtagaagtag
    34621 tgaattctaa tgactgagct atcttttgca tagatgacta tcttgctagt aatgatttgt
    34681 gctacaatag aaacatgaaa aaaagatatc agacattaaa tgagcattac cgtcaactat
    34741 ttggcgcaaa aatgtttaaa gttccgattg atgccggctt tgattgtccc aatcgtgatg
    34801 gaacggtagc tcatggagga tgtacttttt gcacagtatc aggttctgga gatgctattg
    34861 tagcaccaga tgctccaatt aaagagcaat tttataaaga aattgatttt atgcaccgta
    34921 aatggcctga tgtcaatcgc tatttggttt attttcaaaa ctttaccaat actcatgata
    34981 cagttgatgt gattcgcgac cgttacgaac aagctattaa cgaacctgga gttgttggta
    35041 ttaatattgg cacacggcct gactgtctac cagatgatac cattgcttac ttagcagaat
    35101 tatcagaacg catgcatgtg acagtggagc taggcttaca gacaacttat gaagaaactt
    35161 ctaggctaat taacagagca cattcttatg atttgtataa agaaacggtg aggcgactaa
    35221 ggcattaccc caacattaat attgtctcgc acttgattaa tggattgcca aaagaaactc
    35281 atgacatgat gcttgaaaat gtgagacgct gtgtaacaga caatgacatt caaggaatta
    35341 aattgcattt gctgcatttg atgaccaata ctagaatgca aagagattat catgaaggac
    35401 gcttaaagtt gttgagtcaa aaggactatg tttcgattat ttgtgaccag ctagagatta
    35461 tccctaagca tattgtgatt caccgtatta caggagatgc cccacgcgat atgttgattg
    35521 ggcccatgtg gagtctaaat aagtgggaag tattgaatgc cattgataaa gaaatggaaa
    35581 gacgaggaag ctttcagggc tgtaaagttg actaatttgt ctcattttga cggatttgga
    35641 taggagaaaa gtgatgctaa aacgccccat tcatctctcg catgattttt tagcggaggt
    35701 tgtggataag tctagtgtgg ttgttgatgc cacgatgggt aatggaaatg atactgcctt
    35761 tttggcacaa ttagctaaaa aggtttatgc ttttgatgtg caagaacaag ctattagaaa
    35821 aacaagtgag cggttagcgc agctaggatt atcgaacgct gagctgattt tagcgggtca
    35881 tgaagcggtt gatcagtatg tgacagagcc ggtgcgcgca gcgattttta accttggtta
    35941 tttgcccagc gcagataaat ctattattac cttaccaaat accacactcc aagctttatc
    36001 aaaactacta acgttattaa tggtaggtgg gcgtattgct attatggtct attatgggca
    36061 tgatggaggc agtttggaaa aagatgcttt attagatttt gtcaagcaat tagaccaaag
    36121 aaaggtttct gcaatgcttt atcagcctct taatcaggtg aataccccac cttttttaat
    36181 catgttggag aaattagcag acgtttagct cttatccctg tgtcaagtct actagaagtt
    36241 ctgcgattat ttcggtggaa aaagaagaaa tcccataggc tttggctata aatgtgatat
    36301 aatgaagtca ctatattatt tttttaggag ttacattaac atggaagacc ctgtgagtca
    36361 gcccttagtg attcaatttt tattgttagt tgttttaacc ttgttaaatg cttttttttc
    36421 agccagtgaa atggccttag tttctctcaa tcgttctcgg gtggaacaaa aagcagcaga
    36481 cggtgataaa aaatacgctc gtttgttgcg ggttttagag gaacctaatc attttttatc
    36541 aacgattcaa gttgggatta cctttattag tttactatca ggagcaagtt tatcagcttc
    36601 tttgggtaag gtgatctcag gttggctagg taattcagcg accgcaagga cagctggtac
    36661 tatcatctcc ttggttttct tgacttatgt ctctattgtt ttaggagaat tgtatccaaa
    36721 acggattgcc atgaacctca aagacaagtt ggcgattgtt tcagccccta ttatcattgg
    36781 attagggaga ctggttagtc cctttgtatg gctcttatca gcttctacta atttactgag
    36841 ccgacttacc cctatgacct ttgatgatgc agatgagcaa atgacacgtg atgaaatcga
    36901 gtatatgtta tcaaaaagtg aggcgaccct tgatgctgaa gaaattgaga tgttgcaagg
    36961 agttttctca cttgatgaaa tgatggcgcg tgaagtcatg gtcccaagga ccgatgcttt
    37021 catgattgac attaacgatg atccgcttga aaatattcag gaaatcttaa aacaaagttt
    37081 ttcacgcatt cctgtttatg atgtggataa agataaaatt atcggtctca tccacactaa
    37141 gcgtctcttg gagtcaggtt tccgccaggg atttgatcag attaacatgc gaaaaatgtt
    37201 acaagaacct ctttttgttc ccgaaaccat ttttgtagat gatctcttac gccagctgcg
    37261 caatacccaa aatcagatgg ctattttgct agatgaatat ggtggtgtgg caggacttgt
    37321 gactttggaa gacttgcttg aagaaatcgt cggtgaaatc gatgatgaaa ccgataaagc
    37381 agaacaattt gttcatgaga ttggagacaa tacctatatt gttgttggta ctatgacttt
    37441 aaatgagttt aatgactatt ttgataccga actagaatca gatgatgtag ataccattgc
    37501 tggtttttat ttgacaggta tcggaaccat tccaagccag gagcaaaaag aagcctacga
    37561 aatagataac aaagacaaac atttagttct aatcaacgat aaagtcaaag atggccgtat
    37621 tacgaaatta aaattaatcc tgtctaatat agaacagatt attgaggaag actaggctcc
    37681 atgcctagtc tttttgatga aaagtgttat aatgaaaatg taaaaacgtt tacaagtaat
    37741 gaaggagatg caatgactga gaaagattat ggacaagtaa cagggatggt gcattcgaca
    37801 gaaagttttg gttctgtaga tggtccaggc attcgtttta tcattttctt gcaaggctgt
    37861 aaattacgtt gccaatattg ccataatccg gatacttggg agatggaaac caacaattca
    37921 aaaatcagaa cagtcaatga tgtcttgaaa gaagcccttc agtacaaaca tttctgggga
    37981 aaaaaaggag gaattaccgt atctggtggt gaagctatgc ttcaaattga ttttatcact
    38041 gccttattca tcgaagctaa aaaattaggt atccatacca cactagacac ctgtggcttt
    38101 acctatagac cgacacctga ataccatcag gttcttgata acttattggc agtgaccgat
    38161 ttgattttat tggacttaaa agaaattgat gaaaaacaac ataaaattgt cacgcgtcag
    38221 cctaataaaa acatattgca atttgctagg tatttatccg acaagcagat tcctgtctgg
    38281 attcgacatg tcttggttcc aggcttgact gatattgatg atcatttgac acgattgggt
    38341 gagtttgtca aaaccttgaa aaatgtcgat aaatttgaag ttttgcctta ccataccatg
    38401 ggagaattca agtggcgtga gctaggtatt ccttatcagt tagaaggtgt taaaccacca
    38461 actaaggaac gcgttcaaaa tgctaaaaat ctgatgcaga ccgaatctta cacagaatat
    38521 atgaatcgga ttcatcagtc ataagagctg ttatagggtt gaggtttcct caacttttta
    38581 aagtattata agcagatctt ttgtaatctt cctttgattt tagggggtaa ttttgctaaa
    38641 ataaaatgaa taaacaaaat gaggtagaat gattatgtca aaaattttag tttttggtca
    38701 tcaaaatcct gatacggatg ctattgcatc atcttatgct tttgattact tatcccaaaa
    38761 agcgtttggt ttggatactg aagtcgtagc tttaggaaca cctaacgaag aaacagcttt
    38821 tgcccttgat tattttggtg ttgaggcacc acgtgtggta gagtctgcta aagcacaagg
    38881 gtctgaacaa gtgattttga cagaccacaa tgaattccaa caatccattg cagatatccg
    38941 tgaggttgag gtatatggtg tggttgatca ccaccgtgtg gctaattttg aaactgcaaa
    39001 tcctttatac atgcgtgtgg aaccagtagg atcagcctca tctattgttt accgtatgtt
    39061 taaagaaaat ggcatcgagg tgccaaaagc gattgcaggg atgctcttgt ctggtttgat
    39121 ttcagatacc ttgttgctga aatctccaac aactcatgtg tctgatcacc ttgtcgctga
    39181 agaattggca gagctagcag aagtgaactt ggaagactat ggaatggctc ttttaaaagc
    39241 aggtacaaac cttgcaagca aatcagaagt agaattgatt ggtattgatg ccaaaacatt
    39301 tgaattaaat ggcaatgctg tgcgcgtggc acaagtgaac actgttgaca ttgcagaagt
    39361 cttagaacgt caagaagcta ttgaagcagc cattaaagat gccatggctg cagaaggtta
    39421 ttcagatttt gttttgatga tcacggatat tgttaactca aactctgaaa ttctagctat
    39481 tggagcaaac atggacaagg ttgaagcagc ctttaacttc acccttgaca acaatcatgc
    39541 cttcttagca ggtgccgttt ctcgtaaaaa acaagtggtt ccacaattga cagaaagttt
    39601 tggagcttaa tgaaaagacg ctttaaaagg acttgatttt tttgaccaag tccttttgtc
    39661 actcttctat gttataatag aaggtatgat aacagtattt cattcagata aactcaccag
    39721 acaacctttc tttcaagacc ttatcaatta tctcgaccag catgatcacg ttatattacg
    39781 agagatcaaa aaagcctttc ctaatgtgac aggtattgac aaggccatcg aaagctatgt
    39841 tcaagctggc tatattcgcc gtgaaaataa gcgttatgga atcaatcttc ctttggtgag
    39901 ttctgatcag cagctggcct tagacactat gctttttgtg gacacctgtt cagctatgta
    39961 tgaaaatatt ttagcggttg tttttgagac tcagctaaca aaccaaacca atcacgtgat
    40021 gatcaaggaa aagaccaaca tcacgagaga cgatttgacc ctggctaatt atttttaccg
    40081 tctcaaaaga ggtgagaagc catcagctga gcagctggac ttgtatgacc tcttggggga
    40141 tgtgaatcag gaatatgccc ttaaatatat gacaactttt ttgcttaaat tcatgcgcaa
    40201 agaccttgtg atgcaaaaac gtcctgatat atttgtggaa gctctggtta cacttggtta
    40261 cctaaaacaa gtggagccta caacatacca gctgctaatg accttggata aagaaagttt
    40321 aacctttata gcaccataga aaaaagctag gaacaaggac tgttcttagc tttttgagtg
    40381 cttttatttt gtttttgcca ttaagtaaag aaaataaggg gctccgataa gcgacactaa
    40441 aatccctgtc tggatattag tgccaaccag atacactcgc ccgactgtat ctgcaacaag
    40501 aagtaggatc attccgatta aaatactaat gggtattgtt attttatgat tactccctac
    40561 caagtatgta ctaaagtgtc cagctattaa gccgataaaa ctaatattac caaccaaaag
    40621 aacactcaaa gcacctaagc cagctgctaa gacaagtatc aaacgacgct tacggtttaa
    40681 agggagtcct agcccaatag cagtattatc agctaatccc ataatattaa ggaaatgggc
    40741 ttgactataa gtcaatagcc aaaaacacaa taataaagga gcgatgacac tcagagtagg
    40801 ccagtcgtct cctattaatt ggccgctaag ccaattgatg accaaatcga ctttgtagcg
    40861 attaatatga ccaacaagag caaccattag acttgaaagc atggtagtaa cagctacacc
    40921 agtaagaatt aaccgtgtag gatcaatttg tccttgtttt gtcaaagata gccaataaac
    40981 gctaaaggtt gttacaacag caccaagcat ggcaaataaa ggcaagtaat ggctgatatg
    41041 agcttgctca aagaaagaaa aggagaccac aatagccaaa gagatacctg ctcctatagt
    41101 aatacctaat acaccagagt cagctaaggg atttcgtgtt aaacgttgta ataatagccc
    41161 tgataaagca agagaaccgc ctcctagaca agcagctaga attcttggca gacgaatgtt
    41221 aataacgatg aaagatatgg catggctaga ttttcccaaa aacacatgga taaggtccaa
    41281 aaaagataga tgagattctc caagggacaa agctaatccc ataagactta caagtagcag
    41341 gatcaggcta gtatataacc ccaaaaggtg tcggtgagat ttcaatagcg gcctcctctt
    41401 cttattaacc ataaaaagca tggaaaacca attaagctaa ccaatgcccc aagaggggtt
    41461 tcataaggcg gattgagatt acgacaagca atatcaaccc ataccatgaa actagcgcca
    41521 gaaactgcac aaagcggcaa aaggtatcgg taatgatgag gtgtaaagtg tttcataaga
    41581 tgaggaatga ctaagccgat aaaagaaatg cttccagcaa tggctacagc tgctgatgat
    41641 aaaataagaa ccaaaatcat aaagactgca ctgatcaagt tggtcttttg cccaagagct
    41701 tttgcctgag actcacttag actaaggacg gtcaggtgat aagataatag ctgggctaaa
    41761 caaagactaa gaataataag aggagcaata tagccgatca tttgccaatt gaccccgaca
    41821 agacctcctg cttgccagcc gataacagca tttgccagat gatagtaatt ggtaatacct
    41881 tgacctaatg ctgatagcag tatggaaacc atagctcctg ctaagacaag gcggagctga
    41941 tggtagcctt tgccagattg ataagaaagg ccaaagacta aggttgctgc caggctagac
    42001 cctaacaacg aaagcagaat aatgagggaa tagtgcaagt gaggtacaaa cgcataagcc
    42061 agtaccaagg ctagtcctgc tccagcatta atgcctaaaa ggccaggctc agcgatagga
    42121 ttacgtgtga ttgcttgcat gatagttcca gaaacagcta acgcagagcc agttaaggta
    42181 gcaccaaaaa gtctcggtaa tcgtatagcg agtaaaacat tggctttatg gccgttttgc
    42241 tttccaaata aaatagagtt aagatcctga tgtgataaag caacggctcc aaagcgcaga
    42301 tgacagtaaa tagcaacaca taagctaaaa ctaagtagca caaagacaag ccaaaagata
    42361 tgtgacttag tgattatctg cgtttttttt aagcaaaaac gctcgagaca caaaaaggga
    42421 tgcttagttt tcacttgata agattgcctc tcgtaaagtc tctaattgat attctaaaga
    42481 aagaggatca gtaaagtaaa aaacattggc attgactttg atcacatggt gttttttcac
    42541 agctggaatg gattgccata gcttactttc atatagagca gaaccagtct tatcatcttc
    42601 tgcagcaacg acgacataat caccaatata gtctggcaag acttcctgcg acaatgacag
    42661 gtaaccttgt ttaaaaactt cagtcttcac tttttcagga gcatcataat ggaaagcttg
    42721 atggataacc tctccgccac gtccccagtc tttaccaaaa aggtaaacgt ctttttcata
    42781 aagccccata atagtaaagg ttgctttgtc acctgtaacg gctttgactt ctttttcata
    42841 agctgctgtt ttagttttcc aatcttttaa ccatttcttg gctttgcctt ctttgttaaa
    42901 gatgcggccg aagtcagata acacttgtaa ataatcacgt ttgcggtatt caatcgaaat
    42961 aacaggcgca atttctgcca attgtttaat attttcttct gtagagccaa caacaatgag
    43021 gtcaggctta agcgttgtaa tggcttctaa atcagttgca gcaacttgct ttgctttttt
    43081 tacagtcttt gctaagatgg ggtttttctt gtcataagaa gtaaccccga ctagattcat
    43141 atctaatttt ttgaggtaac cagtgtaagt tgaagccaga ctgactactc gcttaggctg
    43201 tttaggaata tctccgtaat aagtcacacc agcaatttga ggcataggcg ataaactttt
    43261 tgaggcggtg ttagaatgat tagttgcttg attaccacag gcgattaagg taatagttgt
    43321 caaacagagt gttaatagta gagttaattt tttcatgtat gctaattctc ctagaataaa
    43381 gttattgaag ctgataagtc agcactatag gacagttgtg gataggatca tcaaccagta
    43441 ccggtttgat ttggaagatg tcttgaatga taggtgaagt cataacatct gctatagtac
    43501 cagtataatg gatcttgcca tgtttcatag caatcagatg atccgaatag cgggctgaaa
    43561 gattgaggtc gtgaagaacc ataacaatag tcttgccggc atccttattt agggatttaa
    43621 cgagctctag gatttctagt tgatgattta aatctaaata agtagttggc tcatctaaaa
    43681 aaatagtatc agtgccttgg gctaatgcca ttgcaagcca aaccctttga cgttgccccc
    43741 cagaaagagc atcaacaggt tgatcagcat aggccatgac attggtggct tgcatagccc
    43801 aatgaatggc ttttttgtca gctggactaa gatttccaaa gtaagattga tggggaaaac
    43861 gtccgtaaga aaccaattcg taaacagtta tgccgttagt tgcttcttga acttgaggta
    43921 aaagagctag ttttttagca acctctttag tttctaatgt ggcaatgttt tgcccattta
    43981 aatatacaac tccctgtttt ggtggtaata atcttgtcag tgcttttaat aaactagact
    44041 tcccacagcc attggcgcca ataatggtcg taattttacc ttcaggaata taaaacgata
    44101 atttatcgat gatggtacgc tgttcatagg caattgtgag gtcttcagca ctaattgttg
    44161 tcatatggtt gtctcctttc taaaaagagt caaagggttg atgaaagtgc acattaaagt
    44221 attcatctgc ccattttaaa atagttgaga agtagcttat tttctcaaaa tcttcactat
    44281 tatagcatag aaaaaaggct taacaaagcc ttttttgatg tgatttttag gatgtattaa
    44341 aaaagaaata ttagtttaga atgattaaaa acaatagcga taatcattct aaactaacgt
    44401 caacatactc tagaggtagt gtctggcgat tgctaaatca ccagcataag ctacttgttg
    44461 tcctttaaca atttgataag catctgcgcc tttcccagcg ataatcacag catcttttgc
    44521 tccttggcaa agagacatgg ctttttgaat agcttgctca cggtcactaa taatctctac
    44581 tgggcgtgcg atatggctgg caatttcttt tgaaatatct tctggatcct cgaaattagg
    44641 gtcatcagca gtgagaatga cggtgaggtt tggatgctga tgaatcaccc taccaaaatc
    44701 agctcgtctg ctctcgcctt tatttcctgg tgcacctaaa atcaacatta atttgcctgt
    44761 ctgatgttct tccacaacgc tgagtaattt ttctaagctg tcaccattat gggcataatc
    44821 aacaaaaact ttagcatgat ttgtcatagt gaggacttcc atacggcctg ggacgcgagt
    44881 cttagcgata cctttttgaa tatcagctag gctagcaccc aaacgaaggc aggcaagtcc
    44941 agctgccata gcattttctt ggttaaaatg gccaattaat tgaatgtcat aatggccagc
    45001 taattgtcct ttagcttcaa aggagaaggc ttggctagtg gtgatctggt tgtcagacaa
    45061 gggaccataa aacacatgct cttgatccgc tacctgatcc gctagaaatg aaaaatgatc
    45121 catcccgcta ttgatcacaa cagctctgct attctccatt aaaagacgct tatgatagaa
    45181 ataatcttca aacgttggat gctcgattgg gccaatatga tcaggactaa tatttaggaa
    45241 aaccccaaca tcgaacgtaa gcccatagac acggtcaacg aggtaagcct gactagaaac
    45301 ttccataatc aagtgggtca tgccattagt cacacactca gccatcatag caaaaagatc
    45361 caagctctca ggagttgtga gttgtgattt gaaaaaggtc ttgccatcta aggtggtatt
    45421 catggtagaa aacatggcag gtttatagga ttctttcaac atgtggtagg caaaataagc
    45481 agccgtcgtc tttcccttag tacctgtaaa agctagtagt ttgagctttt cttgagggtt
    45541 gccatagaaa accatggcaa ttagactcat agcttttttg atatcagtga ccaaaacaac
    45601 gggaatacca agctcgtaat ctacctctga aatatagagt tgtaatccgt tagtgattgc
    45661 ttctttaagg tagtcagctt tgaaagttgc ccctttagca aaaaaaaggg tcttgccatc
    45721 tacttgacgg ctatcgtaac tcaagcgctc aaaactaaag ccttgataat ggtagtggta
    45781 tccgtcggca tcaagaacct cacgaaaatt atggtctttt tttaaaatgt ctaataattg
    45841 ttcaatggtt atcataccct tattttatcc ttaaagttct tgttttacaa gtcacaagca
    45901 aaagtttata ataaagctaa tagaaactag gaaagaatag atatgtcgac agaaaaaaaa
    45961 caactgacac aagaagaatt gatggttcag ggagcagcct ggtccacagc tggcaatttc
    46021 attagccgac ttttgggagt gttatacatt attccctggt atatttggat ggggcaatac
    46081 gcgattcaag ccaacgctct tttcaatatg gggtataatg tttatgctta ttttttattg
    46141 atttcaacca caggactcaa tgttgcgatt gctaagcagg ttgccaagta caattccatg
    46201 ggacaaactg agcatagcta tcaattaatc cgaagtaccc taaaactcat gcttggtctg
    46261 ggccttattt tttcagccat tatgtatctg ggctctcctt tatttgcgag cttatctggt
    46321 ggtgatgaca cacttgttcc cattatgcac agcctttctt tagcagtttt tatttttcct
    46381 gtaatgagtg tcattcgagg tatctttcaa ggccacaata atatcaagcc ttatgcgatt
    46441 agtcagattg ctgagcaact cattcgggtt atctggatgc ttttgaccac cttccttatc
    46501 atgaaattag gttctggtga ttacgcttca gcagtaactc agtcaacttt tgcagccttt
    46561 atcgggatgg tggctagtat gggtgttctg gggtactatc tttggaaaca gggacttcta
    46621 gcagctattt ttagtaagcc agatcatact gtttccattg atatcaaggg cttgttgctt
    46681 gaaaccttaa aagaatccat cccctttatc gtaacaggaa gtgccattca agcctttcaa
    46741 ttgattgatc aatggacttt tgtcaatact atgactcttt ttacagatta tagccgttct
    46801 caattgcttg ttttatttgg ttactttaac gcaaacccag ccaaaattac aatggtttta
    46861 attgcagtag cagcatctat tggtggtgta ggcattgcct tattaactga aaattatgtc
    46921 aaaaaagaca tgaaagcagc tgctcgctta atcattaaca acattgaaat gttagtaatg
    46981 tttttgttac ccgctcttac tggggcaatt attttagcaa gacctctata ttctgttttt
    47041 tacggagcta gcgaggatcg tgccattcac ctctttgtgg cggtcctctt ccaaaccttg
    47101 ttgatggcgc tttacaccct tttttcaccg atgcttcaag ctctttttga aaatcgaaaa
    47161 gcgatttact actttgccta tggtatcttg attaagttag ttttacagat accgcttatt
    47221 tatttgctac atgcttatgg tcctttacta gcgacgacga ttgctttagt ggtgccgatt
    47281 tatttgatgt atcgacgcct atatcaggtt actcatttta accgcaaact gttgcaaaaa
    47341 cgtttattat taaccttgat tgaaacctta ttaatgggac tggtcgtgtt tgtggccaac
    47401 tggctattgg gctatgtctt taaaccgaca ggccgcttga ccagccttct ttacctcctc
    47461 attattggtg gcttgggaat gacggtttac acggcactca ccttgctgac gcatcaactg
    47521 gataaattaa ttggtagcaa agctagtcgc cttcgtcaga aattaggctg gcattaatat
    47581 aatgacacca agaacgattt cgtgagtgct tatcgaaatc gtttttttct taatgatctc
    47641 gcttagtaaa ggtagccgat aaaaaatcag gatttcccaa gcaaactact gatatttttg
    47701 gtataatgat aaaagtgtaa aaaaatagaa ggaagtatat caacatggga aaatgtcaag
    47761 ttatttcgca tccgcttatc caacacaaac tttcaatctt acgtcgtcaa accacatcaa
    47821 ctaaagattt tcgtgagttg gttaatgaaa ttgcgatgct gatgggatat gaagtgtcac
    47881 gcgaccttcc cttagaagat gtcgacatcc aaacgccagt atcaaaaacg gtccaaaaac
    47941 agttagctgg taaaaaatta gctattgttc cgattcttcg tgctggtatt gggatggttg
    48001 atggcttgtt aagtttggta ccagctgcaa aagttggcca tatcggcatg taccgtaatg
    48061 aagaaactct tgaacctgtt gaatacctcg ttaaactacc agaagatatt aaccaacgac
    48121 aaattttcct tgttgatcca atgttggcaa caggtggttc ggctatctta gcagtggatt
    48181 cgttgaaaaa acgtggtgca gcaaatatta agtttgtctg tttagttgca gcaccagaag
    48241 gggtgaaaaa acttcaagaa gctcatccag atattgatat cttcacagca gcacttgatg
    48301 atcatttaaa tgaacatggc tatatcgtgc caggattggg agatgctggt gatcgtttat
    48361 ttgggacaaa ataaaagaga caaccatcaa atagtagcct ttttaggcca atcgttcttg
    48421 attttgttaa aaaaatcaga gagatttctc ttctttaaag gaaaagcaag tttatgattt
    48481 gacctttatt gaccaaaata ttataataaa gacaatcagt aaaaaagaga tgacctagtg
    48541 ggttgccgtc tctcaaaatg acgctactaa aaacccttgt agattggaga atgtattatg
    48601 attcctgttg ttattgaaca aactagccgt ggagaacgtt cttatgacat ttattcacgt
    48661 ttattaaaag accgtattat catgttaaca gggcctgtcg aagacaacat ggccaactct
    48721 gtcatagcgc agctcttatt ccttgacgcg caagacaaca cgaaagatat ctacctatat
    48781 gtcaacacac caggtggctc tgtctcagca ggcttggcta ttgtcgatac catgaacttt
    48841 atcaaggccg atgtgcaaac tattgtcatg ggtatggcag cttctatggg gacagtcatt
    48901 gcttcatcag gaacaaaagg caaacgcttt atgttaccaa atgcagagta tatgatccac
    48961 cagccaatgg gtggcacagg cggtggcacg caacaaacgg atatggctat cgcagcagaa
    49021 catctcttaa aaacacgtca ccgtttagaa aaaatcttag cacaaaatgc tgggaaaacg
    49081 attaaacaaa ttcataaaga tgctgagcgt gattattgga tgagtgctga agaaaccttg
    49141 acttacggtt tcattgatga aatcatggaa aacaacgaac taaaataaag aggatatctg
    49201 caaaagtatt ctagaaattt ctaggatgct ttttctctta gaaaggaaaa taatgataca
    49261 gcctactgca ttaaaacagc ttcaagagtt aaaacgtcag ttcagatccc tttgcaacca
    49321 attatgagat agtttgagga tgatccttag cagctgtgtg caagaagtta tgacgatttc
    49381 ataaaggatg acctagccag tctttcttcg tctcttttac ttaaagtgtg gtataatcag
    49441 attatgctag ccaaaattaa aaaaggcatt gccattaaag gtgttgtaga tcggcttatc
    49501 ctagatctca taacaatgct gtagtaccgc ccttaccttg ctactaaagg cgctgttgaa
    49561 gcacaaattg acttgcaaag gatcttgact gataggtata tgtctggtgg aatcgccaaa
    49621 gcagcaaaaa gaccaagacc cttatttggt ctctaccaaa atataataga aaaggattta
    49681 gaatgtttca aaaacaagaa cgtattggac tcgtcgttta cctgtattat aaccgagatg
    49741 ccagaaagtt atcaaaattt ggtgatttat attaccattc caagcgctct cgttatctca
    49801 ttgtttatat taataaaaat gatttagaca caaaattaga agaaatgaga cgtttgaaat
    49861 gtgttaaaga cattagacca tcagcttttg atgatattga ccgccaattt gtaggtaacc
    49921 ttcatcgcga cgaaacaaac aaccatcaaa agggttaaca accccctagt tactgattag
    49981 cgttttagat ttagttagct tattaaagta agaaggtttt gacagatgct cacactactt
    50041 caagacaatg agacaactag agcattagtg aataactgag ttgacggtca cttctttaat
    50101 aagaacggat aggattggtc ctaaaataga gcactgcaaa gatatgccag tgctttttag
    50161 ctcatttttt gataaaatag aactactaaa aagtgaagga aataagatga tcacaggaaa
    50221 actcataacc gttgaaggtc cagatggcgc agggaaaacg actgttttag agcaactcat
    50281 tccactgtta aaacaaaaag tggctcagga gatcttgaca acaagagagc ctggaggtgt
    50341 tgccatttca gaatacatta gagaacttat tttagacatc aaccatacta ctatggaccc
    50401 taaaacagaa ctcttacttt atattgcggc tcgaaggcag catttggtgg aaaaggtact
    50461 accagctctt gaagcaggcc agttggtttt tattgatcgt ttcatcgata gttcagtagc
    50521 ttatcaaggt gcaggacgcg gtttgatcaa agcagacatt cagtggctca acgagttcgc
    50581 aacagatggt ttagagcctg acttgaccct ttattttgat gttccttctg aaattggttt
    50641 agcacggatt aacgcgaacc aacaaagaga agtcaatcgt ttagatttgg aaacaataga
    50701 gatacatcaa cgagtacgaa aaggatacct agccttagct aaggagcatc caaaacgtat
    50761 tgtcacaatt gatgcgacta aaccattgaa agaagttgtc tctgtcgctt tggaacatgt
    50821 cttagccttg cttttagcct aggataaggg aggggaggaa tggatttagc gcaaaaagct
    50881 cctaacgttt atcaagcttt tcagacgatt ttaaagaaag accgtctgaa tcatgcttat
    50941 cttttttcgg gtgattttgc taatgaagaa atggctcttt ttttagctaa ggtcatcttt
    51001 tgtgagcaga aaaaggatca gacgccctgc gggcattgtc gctcttgtca attgattgaa
    51061 caaggagatt ttgccgatgt gacggtattg gaaccaacag ggcaagtgat taaaacggat
    51121 gtggtcaaag aaatgatggc caacttttct cagacaggat atgaaaacaa acgacaagtt
    51181 tttattatca aagattgtga caaaatgcat gtcaatgccg ctaatagctt gctaaagtat
    51241 attgaggagc ctcagggaga agcttacata tttttattga ccaatgatga taacaaagtg
    51301 cttccgacca ttaaaagtcg gacacaggtt tttcagtttc ctaaaaacga agcctatctt
    51361 taccaattgg cacaagaaaa gggattatta aaccatcagg ctaagctagt agccaaactt
    51421 gccacaaata ccagtcatct agaacgtctg ttgcaaacga gcaagctttt agaactgata
    51481 actcaagcag agcgttttgt atctatttgg ctgaaagatc agttgcaggc atatttagcg
    51541 ttgaaccgtc tggtacagtt agcaactgaa aaagaagaac aagatttagt tttgaccctt
    51601 ttgaccttgc tcttggcaag agagcgtgcg caaacgcctt tgacacaatt ggaggctgtc
    51661 tatcaggcta ggctcatgtg gcagagcaat gttaattttc aaaacacatt agaatatatg
    51721 gtgatgtcag aataagtgca attggaattc gttatgggga aacgaagctt gtcaaaagac
    51781 ttgcccgtac tcccttttca gcagaagagc acatggattt ttacaactgt taaaagattt
    51841 agcggccgat tttaggtcaa gaagtgagct gccccagatt aacagccaag aagatttcat
    51901 tttctatgga ggctatggac cgtgtggcag gccactgtgc tgcattcgtt tttgggaaaa
    51961 tttctgacag tatctattaa aatactaaaa aatcaagggt tatcattgac tttgggtaaa
    52021 gcaacaagcc cttatggccg tttgctttgc tgtctctatg atgaaggtgg cttttaccaa
    52081 taaagcaaga aaaaattccc tgaatatggt accatagtag agacaagtga tggccctgca
    52141 acagtagcag ccgttgatat atttacagat cccattaagg tgcggttaaa agaccagttg
    52201 accttagtca cttatgcttt agaggaggtt aaagtaggtg aataaaaaag aattattcga
    52261 tgcttttgat ggattttccc aaaatttaat ggttacttta gctgaaattg aagccatgaa
    52321 aaaacaagtc caatcactag tagaagaaaa cacgattctt cgcctagaaa atacaaaact
    52381 acgggaacgt ttgagtcacc tagaacatga aacggtagct aaaaatcctt ccaaacaaag
    52441 gaaggatcac ttagagggaa tttatgatga agggtttcat atctgcaatt ttttctatgg
    52501 acaacgtcgt gaaaatgatg aagaatgtat gttttgcaga gaattattag atagaaagta
    52561 agggcatgca ggttcaaaaa agttttaaag acaaaaaaac aagcggaacc ttgtatttgg
    52621 ttccaacccc aattggcaat ctgcaggaca tgacctttag agcagtggca acgttaaaag
    52681 aggttgattt tatttgtgca gaagacacaa gaaacacagg tcttttgcta aaacactttg
    52741 acattgctac caagcaaatc agctttcatg agcacaacgc ctatgagaag attcctgatt
    52801 taattgattt attaatatca ggacggtcac tagctcaggt gtctgatgca ggaatgccat
    52861 cgatttctga tcctgggcat gatttggtca aggctgctat tgatagtgat atcgcagtcg
    52921 ttgctttacc aggtgcctca gctgggatta cagctttgat tgctagtgga ctggctcctc
    52981 aaccccatgt tttttatggg tttttaccca gaaaagcagg gcaacaaaag gctttctttg
    53041 aggacaaaca ccattaccca gaaacacaaa tgttttatga atcgccctat cgcatcaaag
    53101 ataccctgac caatatgttg gcttgttatg gtgatcgtca agtggtgctt gtcagagaat
    53161 taaccaagct ttttgaggag taccaacggg ggtcgatttc agaaatcttg tcctaccttg
    53221 aggaaacacc cctcaaaggg gagtgtctgc tgattgtggc tggagcccaa gtagacagtg
    53281 aggttgagct gacagctgat gttgacttag tgtctctagt gcaaaaagaa attcaagcag
    53341 gagccaagcc aaatcaggct attaaaacaa ttgctaaagc ttaccaggta aatcgccaag
    53401 agctttacca acaatttcat gacttataag tcatcgtagg ttaggagaaa aacaaatgac
    53461 agaagatcaa gcaactatcc ttattttagg agtatacgga atcatattgg ctgtattctt
    53521 attatcagct ttattatgcc ttatcgctaa ctggcgactc tttaaaagag caggttacaa
    53581 aggatggtat agtctcattc ctttctatgc aggttttgtc aaacacaaaa tcacttttgg
    53641 agaagataat aaatggtttt actttattgg ttgggtcatt gctatttatt attactatgt
    53701 gcacttttgc tatgtccgtg cttttggtgg atcaaagggt ctagcagtat ttggcttgtt
    53761 tttcccaggc attgcttctt tgatagtggc ttttggaaaa acttatacca cacaagaatg
    53821 ccaccctgtg ccacatcttt taaactaaga gaaaaaagac catcaattgg atttattgat
    53881 ggtcttttag gtgtttaaat gattttagtc ccgtgaacaa tggccgttcc agtgagttga
    53941 ctcaagcttt ggcaattctc agcagtgacg cctcccccaa tcatgatttc aatgcgttta
    54001 ttggcatagg tcacaagact tttaagctgt tccacattgt ctgtaatagg agtagcttca
    54061 ggtgagccat gagttagcac acgcacaaag ccataatcaa tcagttggtc aagcgcttgg
    54121 tgctggtgat cagtcggaat ccggtcaaaa gccatgtgga aaaccagtgg caagccttgt
    54181 gtagcaggca gtaattgctc gatagcgtcg gtatccagtt gattttctga ggtcagcaag
    54241 cctaagacta gcgcatctga gccagcttca acagctttta agatatcttc ttccatagct
    54301 tttagttcga ggtcgttata gacaaaatcg ccaccgcgag gtcgaatcat ggtcgctacg
    54361 ctaatctttt tatcgtgtaa gagctgacag gcttctttga tgacgccata agatggcgtg
    54421 gtccctccga cagctaggtt atcacagagt tccacacgac tgacttgacc agcatcaagg
    54481 gttggcagta gtgtgaggtt ctcagcacaa aattctttaa tcatttttag ttctccttta
    54541 tcactaatat tatagcacga atgaagctag tcatcaggaa acatttttgt caaatcatgg
    54601 acattatgct atactcacta gtattaaaag taggccaaaa cagcagcaaa tactttgaaa
    54661 aaagattgct atgttctacg gcaatatcag tctttaccaa cgaactctca agaagaaaag
    54721 aaagacaaag cttagcattt taaaaaagcc cccctttttt tgtgaaatga tgaccaaaaa
    54781 caggcgcctc acgcctaaaa cagttaccct aaaggagaac aaatgattac gatttaccaa
    54841 tacccaaaat gtagcacctg ccaaagagcc atggctgaat taaagcaact ggttagtgac
    54901 tttgaagcca ttgacatcaa agctaatcca cccaaagctc aggacctcaa acattggatg
    54961 gaaacatctg gttataccat caaaaatttc tttaatacca gtggtaacag ctaccgcgaa
    55021 ttgggactta aagataaaat agaccagctt agccttgata aagctgctga acttttagcc
    55081 acagatggta tgttgattaa acggcctatt ctgattaagg acggtaacgt cttacaagtt
    55141 ggctatcgca agccatatca agagttggat ttaggataat gcgacaaagt ctcaaaaaag
    55201 gacaaggcaa cattataacg ccttgtcctt ttttgggatc tgtttttaga cattagagat
    55261 caatatctag taaaattggc gtatggtctt ggcgttcccc agaagaaatc atttcagaac
    55321 gcttaacctt atccacgatt cggtttgaag ctagccaata gtcaattctc caaccggtat
    55381 tattgatttt gctggtttta ctacgttgtg cccaccaggt ataaacatga ggaatatcgc
    55441 cgtgcaagtg acgaaaagta tctgtaaagc ctcttgctaa taggttagta aagccttgac
    55501 gttcttcgtc ggtaaaacca ggagaacgtc gattgctgct tggatttgcc aaatcaatct
    55561 ctttatgggc aacgttgtaa tctcccgtag ccaaaacagg cttttgagca tccagttcag
    55621 tcaaataatc agcgtatttg tggtcccaaa tttgacggtc atctaaccgt cttagaccat
    55681 caccagcatt aggcgtataa acctgtgtga cgaaaaagtc ttcaaattct agggtaatga
    55741 tacggccctc agcatccatt gttgttgggg caccaatttc tggaaaagta atgacagggt
    55801 ttaacgtgtt tttgtacagg aacatggtgc cagcatagcc tttcctagca ggctcaactg
    55861 aagaacgcca cacatgcaaa tagtttggaa agtaactaag tagggtctca atatgttttt
    55921 tggtaggccc cttagcagat aatttagttt cttggatggc aataatatcc gcatcttgag
    55981 cgactaaagt gtctaaaaca gcgcgtgata aaagcgcacg aggggactct cctgtgagag
    56041 cagcatttaa ggaatcaatg ttccatgaaa tcagtttcat ttggtttctc tttctaacag
    56101 atagtcttgt tgttattgta acaaaaaacg aaacgataag cgactttggg cacctagccc
    56161 ccataaaaca gtctagccaa atgaagcata gcagcgtaag aacaagacaa ggaggtgatc
    56221 agtgagcata tcgtttgaca gttaagagta ggattactat aatagaaaca taaatgtaag
    56281 cgctaacaaa ataaaaaata taggagaatg tcaatggcac aaaaaacagt catcaccgaa
    56341 gaaacaaccg attttgttat ggatttcaaa acaagtagcg ctgagggaaa tgttgatttt
    56401 attaacgttt ttgaccttga gaaaatggca caacaggtca tccctaaagg agcctttggt
    56461 tatattgcta gtggtgctgg tgataccttt accctccatg aaaatattcg ctcatttaat
    56521 cataaattaa ttgtccctca ctccctcaaa ggggttgaaa atccgtcaac agagattacg
    56581 tttgatggtg atcacttaac ctctcctctt attttagcac ctgtagcggc tcataagctg
    56641 gccaatgaac aaggagaagt agcgtctgcc aaaggattga aggaatttgg aagtatctac
    56701 accactagtt cctactcaac aactgacctg ccagaaatca gtgctgcctt aggtgggaca
    56761 ccccattggt ttcaatttta ttgcagtaaa gacgatggca ttaatcgtaa tattatggat
    56821 cgtgtcaaag cacaaggttg caaagctatc gttttgacag cagatgcaac agttggagga
    56881 aaccgcgaag ttgataggcg aaacggcttt gtttttccgg tcggtatgcc aattgttcaa
    56941 gaatatttac ctgatggtgc aggtaaaaca atggattatg tctataaatc agctaaacaa
    57001 gcgcttacct caaaagatat tgaatatatc gcaacctact caggcctgcc tgtttatgtc
    57061 aaaggaccac agtgtgctga ggataccttg cgggcattgg acgcaggagc atcaggtatc
    57121 tgggtaacca atcatggtgg ccgtcaatta gatggtggtc cagctgcttt tgattcctta
    57181 caagaagtcg ctgaagcagt tgatcacaaa gttcctattg tctttgactc aggtataaga
    57241 cggggtcaac atattttcaa agctcttgct tcaggtgctg accttgttgc cttggggcgt
    57301 ccagcgattt acggcttggc tatgggagga agcattggta ctcgtcaggt ctttgaaaag
    57361 ttaaatgacg agttaaaaat ggttatgcaa ctggctggga cacaaactat ccaagatgtt
    57421 aaagccttta accttcgcca caatccgtat gattcatcga ttccatttga tcaaaatgca
    57481 ctacgcttag attagaacag acaaaaacct ctgctatcat gtcacaaata gtagaggttt
    57541 tacactgcaa aaagaggtat gaaaatccaa taacatagtt acaaggcttt cgtttaatac
    57601 cccccactaa tagattaaaa tgaaagactt cttacattaa tagaagtttc tgttgctttt
    57661 ctcagaaaaa tgtggttaaa taatcaaata ttattaacga aaaatgagtt aatgattaac
    57721 attaaactgg ttttagttaa aacatttagg agggtatcag gtggagaaaa agcaacgttt
    57781 ttcccttaga aaatacaaat caggaacgtt ttcggtctta ataggaagcg ttttcttgat
    57841 gatgacaaca acagtagcag cagatgagct aaccacaacg agtgaaccaa caatcacgaa
    57901 tcacgctcaa caacaagcgc aacatctcac caatacagag ttgagctcag ctgaatcaca
    57961 atccccagac acatcacaaa tcactcccaa gataaatcgt gaaaaagagc aaccacaagg
    58021 tctagtctct gagccaacca caactgagct agctgacaca gatgcagcac caatggctaa
    58081 tacaggtcct gatgcgactc aaaaaagcgc ttctttaccg ccagtcaata cagatgttca
    58141 cgattgggta aaaaccaaag gagcttggga caaggggtac aaaggacaag gtaaggttgt
    58201 tgcagttatt gacacaggga tcgatccggc ccatcaaagc atgcgcatca gtgatgtatc
    58261 aactgctaaa gtaaaatcaa aagaagacat gctagcacgc caaaaagccg ccggtattaa
    58321 ttatgggagt tggataaatg ataaagttgt ttttgcacat aattatgtgg aaaatagcga
    58381 taatatcaaa gaaaatcaat tcgaggattt tgatgaggac tgggaaaact ttgagtttga
    58441 tgcagagcca aaagccatca aaaaacacaa gatctatcgt ccccaatcaa cccaggcacc
    58501 gaaagaaact gttatcaaaa cagaagaaac agatggttca catgatattg actggacaca
    58561 aacagacgat gacaccaaat acgagtcaca cggtatgcat gtgacaggta ttgtagccgg
    58621 taatagtaaa gaagccgctg ctactggaga acgcttttta ggaattgcac cagagaccca
    58681 agtcatgttc atgcgtgttt ttgccaacga cgtcatggga tcagctgaat cactctttat
    58741 caaagctatc gaagatgccg tggccttagg agcagatgtg atcaacctga gtcttgggac
    58801 cgctaatggt gcacagctta gtggcagcaa gcctctaatg gaagcaattg aaaaagctaa
    58861 aaaagccggt gtatcagttg ttgtagcagc aggaaatgag cgcgtctatg gatctgacca
    58921 tgatgatcca ttggcaacaa atccagacta tggtttggtc ggttctccct caacgggtcg
    58981 aacaccaaca tcagtggcag ctataaacag taagtgggtg attcaacgtc taatgacggt
    59041 caaagaatta gaaaaccgtg ccgatttaaa ccatggtaaa gccatctatt cagagtctgt
    59101 cgactttaaa gacataaaag atagcctagg ttatgataaa tcgcatcaat ttgcttatgt
    59161 caaagagtca actgatgcgg gttataacgc acaagacgtt aaaggtaaaa ttgctttaat
    59221 tgaacgtgat cccaataaaa cctatgacga aatgattgct ttggctaaga aacatggagc
    59281 cctgggagta cttattttta ataacaagcc tggtcaatca aaccgctcaa tgcgcctaac
    59341 agctaatggg atggggatac catctgcttt catatcgcac gaatttggta aggccatgtc
    59401 ccaattaaat ggcaatggta caggaagttt agagtttgac agtgtggtct caaaagcacc
    59461 gagtcaaaaa ggcaatgaaa tgaatcattt ttcaaattgg ggcctaactt ctgatggcta
    59521 tttaaaacct gacattactg caccaggggg tgatatctac tctacctata acgataacca
    59581 ctatggtagc caaacaggaa caagtatggc ctctcctcag attgctggcg ccagcctttt
    59641 ggtcaaacaa tacctagaaa agactcagcc aaacttgcca aaagaaaaaa ttgctgatat
    59701 cgttaagaac ctattgatga gcaatgctca aattcatgtt aatccagaga caaaaacgac
    59761 cacctcaccg cgtcagcaag gggcaggatt acttaatatt gacggagctg tcactagcgg
    59821 cctttatgtg acaggaaaag acaactatgg cagtatatca ttaggcaaca tcacagatac
    59881 gatgacgttt gatgtgactg ttcacaacct aagcaataaa gccaaaacat tacgttatga
    59941 cacagaattg ctaacagatc atgtagaccc acaaaagggc cgcttcactt tgacttctcg
    60001 ctccttaaaa acgtaccaag gaggagaagt tacagtccca gccaatggaa aagtgactgt
    60061 aagggttacc atggatgtct cacagttcac aaaagagcta acaaaacaga tgccaaatgg
    60121 ttactatcta gaaggttttg tccgctttag agatagtcaa gatgaccaac taaatagagt
    60181 aaacattcct tttgttggtt ttaaagggca atttgaaaac ttagcagttg cagaagagtc
    60241 catttacagg ttaaaatctc aaggcaaaac tggtttttac tttgatgaat caggtccaaa
    60301 agacgatatc tatgtcggta aacactttac aggactcgtc actcttggtt cagagaccaa
    60361 tgtgtcaacc aaaacgattt ctgacaatgg tctacacaca cttggcacct ttaaaaatgc
    60421 agatggcaaa tttatcttag aaaaaaatgc ccaaggaaac cctgtcttag ccatttctcc
    60481 aaatggtgat aacaaccaag attttgcagc cttcaaaggt gttttcttga gaaaatatca
    60541 aggcttaaaa gcaagtgtct accatgctag tgacaaggaa cacaaaaatc cactgtgggt
    60601 cagcccagaa agctttaaag gagataaaaa ctttaatagt gacattagat ttgcaaaatc
    60661 gacgaccctg ttaggcacag cgttttctgg aaaatcgtta acaggagctg aattaccaga
    60721 tgggtattat cattatgtgg tgtcttatta cccagatgtg gttggtgcca aacgtcaaga
    60781 aatgacattt gacatgattt tagaccgaca aaaaccggta ctatcacaag caacatttga
    60841 tcctgaaaca aaccgattca aaccagaacc cctaaaagac cgtggattag ctggtgttcg
    60901 caaagacagt gtcttttatc tagaaagaaa agacaacaag ccttatacag ttacgataaa
    60961 cgatagctac aaatatgtct cagtagaaga caataaaaca tttgtggagc gacaagctga
    61021 tggcagcttt atcttgccgc ttgataaagc aaaattaggg gatttctatt acatggtcga
    61081 ggattttgca gggaacgtgg ccatcgctaa gttaggagat cacctaccac aaacattagg
    61141 taaaacacca attaaactta agcttacaga cggtaattat cagaccaaag aaacgcttaa
    61201 agataatctt gaaatgacac agtctgacac aggcctagtc acaaatcaag cccagctagc
    61261 agtggtgcac cgcaatcagc cgcaaagcca gctaacaaag atgaatcagg atttctttat
    61321 ctcaccaaac gaagatggga ataaagactt cgtggccttt aaaggcttga aaaataacgt
    61381 gtataatgac ttaacggtta acgtatacgc taaagatgac caccaaaaac aaacccctat
    61441 ctggtctagt caagcaggcg ctagtgcatc cgctattgaa agtacagcct ggtatggcat
    61501 aacagcccga ggaagcaagg tgatgccagg tgattatcag tatgttgtga cctatcgtga
    61561 cgaacatggt aaagaacatc aaaagcagta caccatatct gtgaatgaca aaaaaccaat
    61621 gatcactcag ggacgttttg ataccattaa tggcgttgac cactttactc ctgacaagac
    61681 aaaagccctt ggctcatcag gcattgtccg cgaagaagtc ttttacttgg ccaagaaaaa
    61741 tggccgtaaa tttgatgtga cagaaggtaa agatggtatc acagttagtg acaataaggt
    61801 gtatatccct aaaaatccag atggttctta caccatttca aaaagagatg gtgtcacact
    61861 gtcagattat tactaccttg tcgaagatag agctggtaat gtatcttttg ctaccttgcg
    61921 tgacctaaaa gcggtcggaa aagacaaagc agtagtcaac tttggattag acttaccggt
    61981 ccctgaagac aaacaaatag tgaactttac ctaccttgtg cgggatgcag atggtaaacc
    62041 gattgaaaac ctagagtatt ataataactc aggtaacagt cttatcttgc catatggcaa
    62101 atacacggtc gaattgttga cctatgacac caatgcagcc aaactagagt cagataaaat
    62161 cgtttccttt accttgtcag ctgataacaa cttccagcaa gttaccttta agatgacgat
    62221 gttagcaacc tctcaaataa ctgcccactt tgatcatctt ttgccagaag gcagtcgcgt
    62281 tagccttaaa acagctcaag gtcagctaat cccgcttgaa cagtccttgt atgtgcctaa
    62341 agcttatggc aaaaccgttc aagaaggcac ttacgaagtt gttgtcagcc tgcctaaagg
    62401 ctaccgtatc gaaggcaaca caaaggtgaa taccctacca aatgaagtgc acgaactatc
    62461 attacgcctt gtcaaagtag gagatgcctc agattcaact ggtgatcata aggttatgtc
    62521 aaaaaataat tcacaggctt tgacagcctc tgccacacca accaagacaa cgacctcagc
    62581 aacagcaaaa gccctaccat cagcgggtga aaaaatgggt ctcaagttgc gcatagtagg
    62641 tcttgtgtta ctcggactta cttgcgtctt tagccgaaaa aaatcaacca aagattgata
    62701 acaaaacgca aagagacaac aaatcatccc ttttaacagt cggacctttc tttgagattg
    62761 agctggcaga tgatcatttc ttaacaaaag ttaaagagtt gagcaaagta aggaacagac
    62821 ataaagacca taaaagcaag ccagtttggc ttgcttttat ggtgttattg tcgtgtgcta
    62881 cgatgactga aaaagaacaa cgaacaatga cctcgaatca ccaaaaggac ttgatttgat
    62941 agcttcccta tgctatacta agcctattct ttcaagaagg actccttttg tggaaaagac
    63001 tgaaaaaaag gacactaatc tatccaaaaa ctccagatga gtagctgcaa acggatgcct
    63061 ctgctgtgat caaggggata aagcagactg gcttgtcact acctgagcag gtgtcaaaaa
    63121 aagaagcttt tggctttgac attcaacata ctgagcttta gtattctaga acggagacac
    63181 ccccagtttt gtactcaaaa agcatgaaca gttctgctga tgtgacatct gatttctacg
    63241 tgcgcagtga gccaaaacag ctgctgtttg ctatggaaaa agtggcgcca atcgagattt
    63301 ttgagaccct aggctcaaaa ataaggcata gaattccaaa ggaagtcgct gccgtgagca
    63361 caacctaaga aaaactattc caaaagactt tttctgcaat ttgaaatact gaatttcagt
    63421 attttttctt ttgtaactaa gagcaatgaa tgaggtaaaa aaaggcaaca atgtcaaaaa
    63481 agaaacgaaa acactatcag gtttatgatg gattacgctg tgctatgacg ctttgtttta
    63541 tcagtggcta tgtcaatgcc tttacctata tgacccaagg caaacgtttt gcaggtgttc
    63601 agacaggcaa ccttttgtca tttgccattc gcttgtcaga acagcaactg aaggaggcac
    63661 tgcaattttt acttcccatg atagttttta tgcttgggca gtcctttact tatttcatgc
    63721 accgctgggc cactaaaaaa gggctccact ggtacttatt atcaagcgtt atcttaacag
    63781 ggattgcttt tggaatggcc ctattcacgc cttttcttcc ttccaatgtt acggtagcag
    63841 ctttagcctt ttttgcctct attcaggttg atacgtttaa aaccttacga ggagctagct
    63901 atgctaatgt gatgatgaca ggaaatatca aaaatgccgc ctatttacta accaaaggct
    63961 tgtacgaaaa aaatcacgaa ctaacacata tcggacgcaa caccttaata gtcatcttgg
    64021 cttttgctgt tggggtggtt tgttcgacgt tgctttgcat agcttatggc gagtatgctt
    64081 tgatgcctat tttaatgcct ttactctatg tcaattacct gttggctcag gaattttatc
    64141 acattcaaac caaaatcaaa ccgattaaaa gaacttaacg gacttgtgga gaaagaaagt
    64201 tcatttaggg taagttttta cttaccctcc gttgatttgc tggttttgct gccccttaaa
    64261 atatgatata atagaccatt gatagctgtt acttaacaga aggctgataa aaaaggttcc
    64321 attagccttg agggttgaat ttaaacagga aaaaacgaaa tcctacacta tgcatctcaa
    64381 tcgtactttc atttgagtat ggttctgaaa ggaaactatg atgaaaaaac cattttacat
    64441 tacgacaccc atttattacc catctgggaa attacacatt ggttctgcct atacaactat
    64501 tgcttgtgat gtcttggcac gctacaagcg tctgatgggc catgaggtct tttacctcac
    64561 aggactagat gaacacggac aaaagattca aaccaaggca aaagaagctg gtattacacc
    64621 tcaaacctac gttgataaca tggcaaagga tgtcaaagcc ctttggcaat tgctagatat
    64681 ttcctatgac acatttatcc ggacaacgga cgattaccac gaagaggtcg ttgctgctgt
    64741 ttttgaaaaa ttactggcgc aagatgacat ttaccttggt gaatactctg gttggtattc
    64801 tgtctctgat gaggaatttt tcactgaaag ccaactagaa gaagttttta gagatgaaga
    64861 cggtaaggtt attggaggga ttgctccttc aggtcaccaa gtagagtggg tatcagaaga
    64921 atcttacttc ctacgcctta gcaagtacgc tgaccgcctc gtagccttct ttaaagagcg
    64981 acctgacttt atccaaccag acggtcgtat gaatgaaatg gtgaaaaact ttatcgagcc
    65041 aggcctagaa gatttggctg ttagccgtac tacctttaca tggggtgtac ctgttccatc
    65101 agacccaaaa cacgtggttt atgtctggat cgatgccctc ctaaactacg cgacagctct
    65161 tggttatggt caagctaatc acgctaactt tgataaattc tggaatggaa cggttttcca
    65221 catggttgga aaagatatct tgcgttttca tagcatctac tggccgatct tactcatgat
    65281 gcttgattta ccaatgccag accgcttaat tgcccatggt tggtttgtca tgaaagacgg
    65341 taaaatgtct aaatcaaaag gcaatgtggt ctatccagaa atgttagtgg agcgctttgg
    65401 acttgatcct cttcgttatt acctcatgcg ttctttgcca gttggttcag acgggacctt
    65461 tacccctgaa gattatgtgg gtcgtatcaa ctatgagtta gccaacgacc ttggcaattt
    65521 attgaaccgt accgttgcca tgatcaacaa gtattttgac ggcacggtgc cagcttatgt
    65581 tgacaatgga actgcctttg atgctgactt cagtcaactg attgatgctc agctagcaga
    65641 ctaccataag cacatggaag ctgtagacta cccacgcgcc ttagaagcca tttggaccat
    65701 cattgctcgt accaacaaat acatcgatga aaccgctcct tgggtgctcg ctaaagaaga
    65761 tggtgacaaa gctcaactag ccagtgtcat ggcacacttg gcagctagct tgcgcgtggt
    65821 cgctcatgtg atccaaccct ttatgatgga aacatcagct gctatcatgg cccagcttgg
    65881 cttagcgcct gtttctgact tatcaacact tgctctagca gattttcctg ccaatacaaa
    65941 ggtcgttgcc aagggcacac cgattttccc acgtcttgac atggaagctg agattgacta
    66001 cattaaagcc caaatgggtg acagctcagc tatttcccaa gaaaaagaat gggtccctga
    66061 agaggttgcg ctcaaatctg aaaaagacgt catcacattt gaaacctttg atgctgtgga
    66121 aatccgtgtg gcagaagtca aggaagtgtc aaaagtggaa ggttcagaaa aattgctgcg
    66181 ctttagagta gatgcaggag acgggcaaga ccgtcaaatc ttgtcaggta ttgccaaatg
    66241 ctaccccaac gagcaagaat tagtgggtaa aaaactacaa attgttgcta acctgaaacc
    66301 gcgtaaaatg atgaaacaat acatcagcca aggcatgatt ttgtcagcag agcatggaga
    66361 tcagctaacg gtcttaaccg ttgattcctc tgttccaaat ggaagtatca ttggctgatg
    66421 ctgacctatt attcaaaaac ctaagcaaga atatgtgctt aggttttttg attgccttca
    66481 agaaagatga ataacgagat gggtgatatg gcatcaaaag cataactatc ctaggacctg
    66541 tcctagtaag attgctgtgc ttttgacaag tgaacagaga ggtcttaaac tatatcttgt
    66601 cataaaaaag attgcaaaac actatatctt gtgttattat ggtttttata aaagttaagc
    66661 gtgcttaact ttagccaaac aaaagaggac actagagcgt gtcccacaag acagttgagc
    66721 ccttcgcttt tttagtagag taggagtgct caagtcaaaa agagacagcc catcaaacca
    66781 ttgctgttta gcaggtcttt ttgtgttgct caaaaaacag ttcctgtctg tttggcgtct
    66841 agtgatgacc taggcttagc gctactagac ttttgtttga aaaatacctc aagccttgaa
    66901 ggagacaaat gacccaacat tattatgaac gttcgcaatc cccaattgaa tacgccctat
    66961 ctgaaacaca aaaacagttg cgctccatca attggaatta ccttaatgat gacaaagatt
    67021 tggaagtgtg gaaccgtgtc actcaaaatt tttggttgcc tgaaaaggtt cctgtttcta
    67081 atgatttaaa ttcttggcgc tccttgggtg aggattggca acagctcatc acaaggacct
    67141 acactgggtt gaccttacta gatacagtac aagcaacggt tggtgatgtg gcacaaattc
    67201 agcattcaca aaccgaccac gaacaagtca tctatacgaa ctttgccttt atggtgggga
    67261 ttcatgcccg ctcttacggg acgatttttt cgaccctttg cagcagcgag caaatcgaag
    67321 aagcacatga atgggtggtc tcaacacaga gcttgcaaga ccgttcccgt gtcttgattc
    67381 cttactatac gggtgatgac cctttgaaat caaaagtagc agcagctatg atgccaggat
    67441 ttttgctgta tggcggcttt taccttcctt tttacctatc agcacgtggt aaaatgccaa
    67501 acacctctga tatcatccgc ctgattttac gcgacaaagt tattcacaac tattacagcg
    67561 gttacaaata ccaacaaaaa gtagcacgtc ttagcccaga aaaacaggct gaaatgaagg
    67621 cctttgtctt tgacttgctc tatgaactca tcgaccttga aaaagcttac ttgagagaac
    67681 tgtatgcagg ctttgatttg gcagaagatg ctatccgttt tagcctttat aacgctggaa
    67741 aattccttca aaatttaggt tatgattcgc ccttcacaga tgaagaaacc cgtatctcac
    67801 ctgaagtatt tgctcagcta tcagcgcgtg cagacgaaaa ccatgacttt ttctcaggca
    67861 atggctcatc ttatgtgatg gggatcaccg aagaaaccac agatgacgat tgggagtttt
    67921 aagaaatggc agagctgatt attgtgtatt tttcatctaa gtccaataac acccatcgct
    67981 tcgtccaaaa attaggcctg cctgctcagc gcataccagt agataatagg ccacttgaag
    68041 tttcaaccca ttaccttttg attgtgccta cctatgcagc tggtggttca gatgccaaag
    68101 gagccgttcc taaacaagtg attcgttttt tgaataatcc taacaatcgt aaacattgta
    68161 agggagtgat ctcttcagga aataccaatt ttggcgatac ctttgcctta gcaggcccta
    68221 tcatttctca aaaattgcag gtccccctat tacaccaatt tgaactatta ggcactgcta
    68281 cagatgtcaa aaaggtacag gcgatctttg cccgcttaaa gcatcacaca cacgacaagc
    68341 aaaaacaaat caacaacctg attacagaaa ggacacaccc atgtcacaaa ccaatgcgtc
    68401 atacctctca ttaaatgcac tgacccgttt taaaaaacca gacggcagct accattttga
    68461 tagcgataaa gaagctgtta ggcgctacct ggaagaacat gtctctccca atcaaatggc
    68521 ttttaactca ctagaagata agctagctta cctcatcaat gaagggtatt atgagcaggc
    68581 catttttgat gcctatccta acgaccttat caaggaggcc tttcattatg cctatcaaca
    68641 aggctatcgc tttttaaatc tcatgggcgc tatgaaattt taccagtcct atgccttaaa
    68701 aaccttggac ggtaagcagt atctagaaac atttgaagac cgtgctgtga tgaatgcact
    68761 ctttttagct gatggagatc aaacctttgt ctttgacgtg attgatgcca tcttgcaccg
    68821 acgctttcaa ccagctaccc caacgttttt aaatgccgga aaaaaacgcc gtggcgaata
    68881 catttcgtgc tatcttcttc gtgtcgaaga caatatggaa tctatctctc gcgccattag
    68941 caccagcttg caactctcaa aaagaggagg cggagtcgcc ttgtgcctca ccaacctcag
    69001 agaaatcgga gcaccgataa aagggattga aaatcaggca acaggcatcg ttcctgtcat
    69061 gaaactacta gaggactctt tttcctatgc caatcaacta ggtcagcgcc aaggagcagg
    69121 tgcggtttac cttcatgccc atcatcctga ggtcttgacc tttttagaca ccaaacgtga
    69181 aaatgccgat gagaaaattc gcattaagtc cctagcattg ggacttgtga tcccagatat
    69241 taccttccag ttagccaaag aaaacaaaga catggctctc ttttcaccct atgatatcaa
    69301 gcgtgcctat ggcaaggaca tgtcagacat ctccatcaca gaggaatacg ataaactgct
    69361 agccaatcca gccatcaaaa agacctacat cagtgctaga aagttctttc agttaattgc
    69421 agagctacat tttgagtcag gctaccctta cctcttgttt gatgacacgg tcaataagcg
    69481 caatcctcat gccaaaaaag gcagaatcgt catgtctaac ctgtgttctg aaatcgctca
    69541 agtcagcacc ccaagcactt tcaaagaaga tttgagtttt gaaaccattg gagaggatat
    69601 ctgctgtaat ttagggtcta tcaatattgc ccaggctatg gcagatgcgc cacactttga
    69661 acagctcatc acaacgagca tcagagcact tgatcgtgtc tctagagtgt ctgacctgaa
    69721 ttgtgcgcct tctgttgaga caggcaatgc agccaaccat gcagtaggat taggcgccat
    69781 gaacctacat gggtttttgg caaccaacca catctactat gatacaaaag aagccgttga
    69841 ctttacagat ctgtttttcc atgccatggc ctattatgct tttaaagcct cttgccaatt
    69901 agccaaagaa aaaggcgctt ttgcaggatt ttcgttatca acctatgcag atggcactta
    69961 ttttgccaag tatttgcaag aagatgccaa gccacaaaca gccaaggttg ccacattgtt
    70021 gcaagattac ggcttcacat tgccaacggt ggcggattgg caagccctag tagcagatat
    70081 caagcagttt ggtctagcca atgcgcactt gctagcggtt gctccgacag gctccatcag
    70141 ctacttatca tcctgcactc cgagtctaca accagtcgtt gctcctgttg aggtccgaaa
    70201 agaaggtagc ctgggcagga tttacgtccc tgcctatcag attgaccagg ctaactatgc
    70261 ttactatgaa cgtggtgcct atgaggtcgg cccaaaagcc atcatcgacg ttgtagctgc
    70321 tgcccaaaaa cacgttgacc aagccatctc attgaccctg tttatgaccg atcaagcgac
    70381 cacacgtgac cttaaccgct cctatatcca agcttttaag caaaactgtg catcgatcta
    70441 ttatgtgcga gtgaggcaag acgtcctagc aggcagcgaa cagtatgacg aggatagtct
    70501 tgtgacagct cctggagcta gtgatgagac caccacagag tgtcaaagct gtatgatcta
    70561 acagctacta gaaagctctc gtgtccccta tcacatgcat aggatcagtg cactcgacct
    70621 ttcaagacaa gcaagcatca gctcttgctt gtcttttttt ggccttaaag cccgttagtc
    70681 tgctgctatg cgaggctttt tttgagcatt agaacgtcaa aaaaaaggac atggagtcct
    70741 tttttggtga tcggtgttga ggccgtcaca aactgccctt gaaatacgct tctatgtgga
    70801 gctttttttg gtcttgtgac acgtaagctc caacgacctc cagctgacag cctcttggaa
    70861 acaagagctc aacctctgaa ggcacagccg aataaggctc gacaaaggct gccttggccc
    70921 cttttttgac acagatgcgc acctccaccg gtcgatgggt catggcgccg tttttcaagg
    70981 ctgtcgtgct cataaaactg tgcttggtgt agcgtgtgcc aagcttgatc ttacaaagga
    71041 tatgagggtc aaactgatgg ttacggtagt aagacgtgag atcagcgtgt gaaacaccga
    71101 tatcacgcaa aaacgtctcg tacacatagc ggtataccac aatgttccac gggatgacta
    71161 gccggtgagt cgcagcatcg agctgggcca cctgatccct tagctcaggc gtgagttggc
    71221 tgagctcacc tttggtcttg tctaggctgg tgttgatagg ggctgcctgc tggcaggtat
    71281 aagcagccat cgcctcttgc tcagcccttg ggtagacgag acccttgccc cagcgctttt
    71341 taatcagtgt ctcagcgccc ttttgatccg aaaaggtaaa ataagcaggc gtcccctcac
    71401 aaaccgcccg ctcatagtgc tcacagacaa aaagctcgac caagccctca gtttgccaga
    71461 ctagactaaa acagctaaga agaaggatca tagccagttg atagcgcttt tttagcatag
    71521 ttccccctga caccagccca aaaggctgac ccttccccta ggccttttgg ctagctcatg
    71581 ataccaccag tttctcagac aggctaatct ttttgtcatc tctttctccc taaacagact
    71641 ctcttatcat gatattatgc tattatgagc gatttgtcaa tccatagcaa ccgtttttta
    71701 gccagataag taagcttttg acctagaggc agacaagagt ggcagtacct gccgtttgct
    71761 gtggtggcta ataaggacta acataaaata tcaaacgctt tcaaaaacag ctcctaagct
    71821 taaaaaagct gatgaacaat tttttgagtt taagagagat tgccatgatt ttctaatcat
    71881 ttgatgttta aaatgataaa aaaatgaact tgaaatgaaa gaatactagt agtaaactaa
    71941 aaatatatca aaaataatga aatggagtga ttttatgaaa acaaaatcaa aacgcttttt
    72001 aaatctagca accctttgct tggccctact aggaacaact ttgctaatga cacgtcccgt
    72061 aaaggcggag gtgtcagaaa ttgggcacga tcacgtaaca atcagttcta atggtcaaac
    72121 agatgagggt gctgcatatg gtagaggcca tgatgatgga agtaagtttg gatatgaagc
    72181 aggattacaa tcgagttgga atgagtctga acccccatca tcagataaaa tacctgagcc
    72241 tagtgtgaat ccatatgaaa gtagtaatga acaagataga gaggattata aagaaggttt
    72301 tcgtgatgga tatcctgggg gctatgtcgc aggctggaga aaaactcatc caatagaagc
    72361 tactcttcaa tatttatggt atacggtatc tagttggttt gaaagcttat ttaataatag
    72421 taagtagata tttgtttgtt gattaaagtt acttaaggta aaataaaatg tctgtcagca
    72481 acttcgtgct agtggctttt gttttacctt tcccacacta atctgctata attgggataa
    72541 tccctttagt agtcaggcca cctctgatag gggtggcctt ttttgggttt tagtgacccg
    72601 tgtgttgaaa aaggagcatt tatgccagaa aagaaagtgt tgcccgtcct aagcatggtg
    72661 gtgagttttg tctgcctgct tgatcatatc ttcttttttg ggctctttgt caactgtagt
    72721 gggtgactta tagctaaaca cgtgaggaga cgagactcgt cttctctttt gttatgttca
    72781 aagcgaggta aatgcgtttt ttaaagttat caaagttccg aaagccaaaa gcattgcgtt
    72841 tgatgtgttt gatgagttta ttggttgctt ctagtttggc gtttgaacaa ggaagctcaa
    72901 tgacattagt gacatagttt ttgtatcgca tcagggtgtt caaagccgtt ttaaagatgt
    72961 tattgagcag aagtaacacc ttttgaatta agtcaaaaaa tgctcagtat tcttctcttg
    73021 taagtgaaaa aggagtaact gataaaggtc atagtaatct tttaattcag gaacgggatt
    73081 aaatagttta ttgagacatt gtttaggagt tagcgtttcc ctaaaggttc tagagtagaa
    73141 ggcgttgagc gagagttttc ggctaccttt tgaatgagtt gacagtagta tttaagaact
    73201 ctgtattcca gagacttttt gtcatattgc ttcatgatgt gaatccgggt ttgactgagc
    73261 gctctgttca tgtgctgaac aataggaaac gatctaggac gatgttagct tgaggaaata
    73321 gctttttaat gagcgaaata tagcttcctg acatatcaac ggtaacgatt ttgacactgt
    73381 ttctagcctc tttagagtat ctaaagaagt gatttcgaat ggttgtttgt cgccggttgt
    73441 ccagtatgga gatgattttt ttggactcaa aatcttgagc gataaaggcg agttcgccct
    73501 tttgatagga aaatccatcc caagacaaca cctcgggtag tttagagaag tcttccttga
    73561 ttacaaactg gttgagtttt cggtagacgg tagaagatga tatagccgac tgttgagcga
    73621 tgttagtgag agctcctcga ttaaccaagg tttgtgcgac tttttgtctg aggggctcag
    73681 agatctgaca gtttttttga accagacttg tttccgctac agccactttt cgacaggatt
    73741 tgcattgaga tcttctcttt tttaaacgaa tgagactagg aaaaccacca atttcgataa
    73801 aggggatttt agaatgtttc tgggagtcgt atttaatctg aactccttta cagtgtttac
    73861 acttaggtag ggatagtcaa gtgtggcgaa gacttcgata agtgtctcgc gttgaaaaac
    73921 cttgttcaag gtgatgtgtt tatctttaat tctaatcaat tctgtagtat gatagagttg
    73981 tctcatatga ttctttctaa tgatggtttg gtcgctttgc attataagtc atatgggatt
    74041 ttttgctact tatagttacc tctacttgcc gtttgtagca agtagtctag cattgtaggt
    74101 cttgtataaa acaaaagcaa gtgttcgctg gctgggcttg tagtagcagt aacagtataa
    74161 tatgaaccga cagctattcc ctattaaaat agacgcaaat gtccacgctt tcactgtagt
    74221 tgctagtaag gtctaacaca aaacatcaaa ggctttcaaa aaaactccta agcgcaaaaa
    74281 ggcggactaa cagccccaag caagcacttt ctgaggtaat aagagattgc catgattttc
    74341 taatcatttg atgtttaaaa tgataaaaaa atgaacttga aatgaaagag tgcgagtagt
    74401 aaactatgac cgtatcaaaa ataatgaaat ggagtgattt tatgaaaaca aaatcaaaac
    74461 gctttttaaa tctagcaacc ctttgcttgg ccctactagg aacgactttg ctaatgggac
    74521 aacccataaa ggcggaggca gtagtatctg atttgaatga tgcagtctct tcgatgggag
    74581 atacagcaga ggaaactgac gtcaatatcg atggtcaaga agacgaagaa gacgaagaag
    74641 acgatgctta tatgcaaggg agaagactgg gagagaaaga ggggtatgaa gctggtcaaa
    74701 aagacaacgc tcccagatta tttgacagta gtacgctaga gccccctact aatccttacg
    74761 aggatgcggg tgatacattg aatagtaatt ggtttaaaag tggttacagc gatgcttatg
    74821 gtcaagcata tgagcaggga tggaatgata ctcatccgat acaatcaact ttaatttggc
    74881 tgtgggggat agtaaggaac ttatttagat tttagattta ggtgacggtt accaacaaca
    74941 aagtaattaa tattacgtta taaaaagcta gtatcgcttt tgaggatagt gttatttact
    75001 cttttgagat atttgaaata ctataacact aaaatgaatc cttttatcac aagcatttcc
    75061 cccactaatc tgctataatt gggatagtcc ctttagtagt caggccacct ctgatagggg
    75121 tggctttttt gggttttagt gacccgtgtg ttgagaaagg agcatttatg ccagaaaaga
    75181 aagtgttgcc cgtcttaagc atggtggtga gttttgtctg cctgcttgat catatcttct
    75241 tttttgctac ttatagttat ctctacttgc cgcttgtagc aagtagtcta gctcttatca
    75301 gtctggtgca aaacaaaggc aggcaaaagg tttggtcgct agctgggctt atcttagctg
    75361 ctctagccgt ggcagtagtg gcctatgcct actatgaccc aaccgtcatc ccctattaac
    75421 cttatctcct ctttgcacgc aatcagcagc acaaaaagca cccttacagg tgcttagatt
    75481 gaaaaaggtc ttttgtgata ctttttctga ggcggtgcgg acggtagcga cttcctttgg
    75541 aattccctga cttatttttg agacctaagg tctcaaaaat cccgagtggc gtcctctcgt
    75601 attgacgcca ctttcaccat gacaaaaatc atctgttttg gctccctttg tgtgtaaaaa
    75661 tcggaaaccg tatgtcacat cagcagagct gtttatgctt tttgaacata gaactaggtt
    75721 tgtctaggtt ctaagcacct gtaagggtgc tttttgtact ttagccaacc tcctcatagc
    75781 ctagcaaacc ctcactgaaa cagtccctta aagttccacc aagcgtcttg aaaaacatcg
    75841 cgtactttat cccgccatgt tttttgttcc tctcttagac gagaattttc aaaaaggttt
    75901 tcggcatatt cttcatcaaa tgctttatat tgttcatttt tgagtgtttc tgaatcaata
    75961 aaagtcatca ttccagctaa aaatccatca tctccttgaa aataaatagt aaattctttt
    76021 ggaggttgcg acgttgagat atcgagagtg actgtagtag tcactgaatt gctgtttcgt
    76081 tgtttcgtgt ttttatcaat ccatgcagac catcctggag gaagtgtaac agtgacttta
    76141 ttacctgtaa tgtgaacagg aatttcattt ctgttatcat ctaaaacttt ttgttgtctt
    76201 ggaagaggta cccaagaact ctcctccgct ctgacgctac tagttacccc gatggtaaag
    76261 agtgccagta gcaaagttaa tgtctttttc attttttcct ctccttttgc tcatctttta
    76321 agacaagggt tattatacca attcttgcgc taaaaagata gggagttcat gtcttgtggt
    76381 tgggaaatgg cgcgactatt cttggtagga tcagctagtt tttttcctag tcagtcgcta
    76441 gctgttgcca ttttaccttt aaaggtcgtt tgggtattat gtcatatttt atgagcggtt
    76501 ttatatttgg tatcaatatc ttatagggca attgctcata tttattgaaa gctcttatct
    76561 tatttagtcc aaagataaat atcaaaatgg ctgaaatctt tcatatttat agtcttattg
    76621 tctttatatt ttttaaaaat atcactcctt gtactagatg aggttgcatc gtataagtta
    76681 aaactttcat gtttattgcc attgatcgca atttctaatt gcccttttat gtatggagaa
    76741 ttaggatcat aaattttgta tgtttgcata agatattgtc tgattttgaa gtcaaattct
    76801 tgaatcgtaa aaatacgttt atctattttt atgggattta ttagtgtttt ttgctggact
    76861 ccatctatta gtaaattacc tacaatttta ctattttccg aattactgtt tactgatggt
    76921 gtaaccccac catatatata ataaacatca taacgagtaa atatgtacgg aagaccaaaa
    76981 atatttactt tttgattttt cgtaaacttt gttgtaatat agctctcgac ctcagaatca
    77041 actgaaaaat ttttcttttt ataactggaa acatcaatat aaaaatcatg agtggtcaag
    77101 taatcaatat tacaattcgt ataatctact ggtctgattt cgtatgcgta atttaattgt
    77161 agcttaacgt ctttaatctt ttcactatct gattttacac ttccgtaccc atgaaagatt
    77221 attataacta aaattattgt ttttattaat cttttcatac ctctcctcgc tcaccccgtg
    77281 ccccacaaac tactttatcc taaaaaacaa taaaatcaac attgaggact tttttggttc
    77341 ccataattgt taactatgtc attttagagc aatcatatag agactaagat ataattttac
    77401 caaagttttg aaggctattg aagagtgact ttctccctta atttatttaa ttaaagatac
    77461 taaaattctt gatattcata aagctcaatc aggaaggaca aaatcaaaga gcttaccagt
    77521 tttctggtaa tgctgatcat gtctcctttg atatacctgt tagctacagc ttttttcaat
    77581 tcgtgatatg ttaacatttt tatcctccta cttaatctat tcgtaaaaaa tctcttaaaa
    77641 tagacattta aaaaaaagtc cattataacg gatatgcccg tgtgcgaata catgttcggg
    77701 taaatatttt aaatcaagat gtttgatgtt tgtgtgtgca aaaacaaaaa aatcgccctc
    77761 gattgatgat atgatacgtc ttaagtagac aggctaaata accaaaatct actcaagagg
    77821 tatttttatg ccagaaaaga aagggctgct cgtcttaagc atggtagtga gccttgtgtc
    77881 cctgcttgat catatcttct tttttgctac ttatagttat ctttacttgc cacttgtagc
    77941 aagtagtcta gctattatta gtctggtgca aaacaaagga aggcaaaagg tttggtcgat
    78001 agctgcttta gccgtagcag tagtgaccta tacccaacgg ttattcctta tcaaatgcaa
    78061 agtccctccc tcttatataa actatcaaat actttcaaaa acagttccta aagctcaaaa
    78121 aggttatcta actgctccaa gcaggcactt tctgtgataa ggatagcttg ccattttttt
    78181 ctaatcattt gatgtttaaa atgataaaaa aatgaacttg aaatgaaagg aatgagaggt
    78241 gtaaactaaa agtaccaaat aaacaatgaa tacggagtga ttttatgaaa acaagaccaa
    78301 agcgcttttt aaatctagca acccttagct tggccctttt gggcacaacc ttactaatgg
    78361 cacaaccggt aaaggcggat aatgatacta gggagtctca agagcgcgta gaccaaagaa
    78421 tagaagatcc ttatgatgat ggaaaaaatg ctgggagaaa ggatggttat gaatcaggga
    78481 atcataaggg aatctctgaa gagcctccaa ctaaaactcc tgaacctccg actaatcctt
    78541 atagccgtga tagggtgaaa agcaagaagt atagagatgg ttatcaggaa tggtatgtct
    78601 atggatacta tgaaggttgg catagagcaa atgatgagga taaaaataaa gagtcttctg
    78661 accattctcg agatcaggat ttagaaggta cagaacagac agatggacag gatgaggata
    78721 aaaataaaga gtcttctgac cattctcgaa atcaggattt agaaggtaca gaacagacag
    78781 atactgaata ttcagcaatt atcagtacat tgtatggaat tgctggagtt gtattggaat
    78841 atgtgctatc ttggtttagt atctaagatt tagttttggt tactggataa tggtttaaat
    78901 atttattatt atctaaaaat ggcgtgatca aattttgatg atttggttaa tattgtttag
    78961 aacagactga agacaaagct cttagtaact aaattctaag ggctttgtct tcagtctgag
    79021 gcaccttacg gggtgtcttt tattatttag gtggcttaat gaattggtta aaatcttttt
    79081 agtttagtaa aattgctatt taaggttagc cacctctcgt atggtcacag ttgatgaatt
    79141 atgctatagt atagacataa aaaatagttc aaatcccttc ttgcctgttg gtggattttg
    79201 aactgaaagc ctctctgatt gcagttggta ggcttttttg atgctttttc gtactttttt
    79261 tatttattac gctaaaaaat gttatacttg atgaagaaaa aggagagttt agaacgttaa
    79321 gatacctcac agcagattga tagaggatat ggaaaaaggt tagctttccc aagagatgcc
    79381 gtttgggaat ggtataacaa taactggcag aagttataag taaaacaaga acaaattaac
    79441 tcagatgatt tttagacgtt cccacgcgtg tgcgaattaa ttggaaaaaa atgagaaaat
    79501 acgatataca aaaaaggaga acaatatgac atttgaagaa attttaccag gtttaaaagc
    79561 caagaaaaaa tatgtacgta caggttgggg tggcgctgaa aattatgtgc agttgtttga
    79621 tacccttgaa gtggatggga aagtactaca ggcgacgcct tattttctga ttcatgttac
    79681 tggtgaaggt gaaggttttt ccatgtgggc accgacacca tgtgatgtgt tagcagagga
    79741 ttggatcgag gtcaatgact aaagttgttt tagtgacggg ctgtgctagt gggattggtt
    79801 atgcacaggc ccgctatttt ttgagacaag ggtatcacgt atatggtgtg gataagtcgg
    79861 ataagccgga cttaagcggt aactttcact ttatcaaatt ggatttatcc tctgagttat
    79921 ccccactctt taaagtggtc cccagtgttg atattttgtg taatactgca gggattttag
    79981 atgcctacaa gccactttta gacgttagtg atgaagaagt ggaacaccta tttgatatta
    80041 atttttttgc gacggtgaag ttaacacgtc attatcttag acgtatggtg gaaaagcagt
    80101 caggtgttat catcaatatg tgctcaatag caagttttat agcgggtggt ggtggtgttg
    80161 cctatacgag ttctaagcat gcgcttgcgg gcttcacgcg tcaattggct ttggattacg
    80221 ccaaagatca gattcacatc tttggtatag cgccaggtgc tgtcaaaacc gctatgacgg
    80281 ctagcgactt tgagcctggt ggcttagcag aatgggtagc tcgtgagacg ccaattgggc
    80341 gttggactga accagatgaa gttgctgaat taacgggatt tcttgcgtca ggaaaagcga
    80401 gatcaatgca aggtgaaatt gtcaaaattg acggtggctg gactttgaaa tgatcacatg
    80461 ccttagcttg agctggcgca gtaagcccta gaggtgtgat gagtcaaaca gtcaaaggag
    80521 atgaacaaat gaaattagcg gttttgggga caggtatgat tgttaaggaa gttttgcctg
    80581 tcttgcagaa aattgatggt attgatctag ttgctatctt atcaacagtt agaagtttaa
    80641 agacagctaa agacctcgct aaggcatatc acatgcctct agctacgagt gaatatgagg
    80701 ctgtcttagg caatgaggag attgacacgg tctatattgg actgccaaat cacctgcatt
    80761 ttgcctatgc taaggaggct cttctggctg gtaaacatgt catttgtgaa aagcccttta
    80821 ccatgacagc aggagaatta gatgaactgg tggtaatcgc taaaaaacga aagcttattt
    80881 tgttagaagc gattacgaat cagtatttaa acaacatgac ctttatcaaa gagcatcttg
    80941 accaacttgg cgatatcaaa attgtagaat gcaattattc acaatattct tcacgctacg
    81001 atgtcttcaa acgaggtgat atcgcgccag cttttaatcc taaaatgggt ggtggagctt
    81061 tacgtgattt aaacatttac aacattcatt ttgtggtagg attatttggt cgccctaaaa
    81121 cggttcaata tttagccaat gtcgaaaaag gcattgacac atcaggcatg cttgtcatgg
    81181 actatgagca gtttaaagtg gtgtgtatcg gggccaaaga ctgcactgcg gaaatcaaaa
    81241 caaccatcca aggtaataaa gggtcactgg cagtgcttgg agcaacaaat acccttcctc
    81301 aggttcagtt aagtctacac ggtcacgaag cacaagtggt taatcacaac aagtatgacc
    81361 accggatgta tgaagagttt gtcgctttta gggacatgat tgaccaaaga gactttgaga
    81421 aagtgaatca ggctttggag catagccgag ctgtcatggc tgtgttggag cgagctgttc
    81481 attcgtgatg gtaatctggt agccattgcc ttttgtgcag ttgctatggt aatggttgaa
    81541 agacgtgttt tcacgagggt taaccccctc gtgctttttt ggtaaaaata acttgttcag
    81601 gatttgggcc ttctttgtga gatgagagat gcctgacgaa ttgatttgat taaaataatg
    81661 ataaagccaa acgatttaag aaatgaccgt tcggaaattc tgccccaaaa ggtctctaga
    81721 agcagtaaaa tcgaatttgt aagcgttgac actgctgcat aactctgtta cactaagaga
    81781 atgtcatgac aaaaattaca gtgtaggagt ttaattgttt atggaagagg attataacaa
    81841 aagagaacct gagaagttta cgcaatttct gcgccgtcaa aaggtcgtct tttttgtcgc
    81901 attttttggt tatgtgtgtg cttacttggt acgcaacaat ttcaaactaa tgtcaaacac
    81961 tattatggtc caaaacggtt gggacaaggc tcaaattgcg accttgttat cgtgtttgac
    82021 cgtttcttat ggcttagcaa aattctatat gggggcctta ggggatcgtg ttagcttgag
    82081 aaagctcttt tcgatcagct tgggtgcaag cgctttgatt tgtattttaa ttggtttttt
    82141 caatagttca atggtagtgt tagggatact gctagtcttg tgtggtgttg tacaaggtgc
    82201 cttggcacct gcctcacaag ccatgattgc caattatttt ccaaataaaa cacgcggcgg
    82261 agccatcgct ggatggaaca tttctcaaaa catgggatca gccctcttgc cattaaccat
    82321 cgccttgctc accagtatgg gcttggtggt accagctaat ggcaatattt tacttgcctt
    82381 tttaatccct ggtgttttag tgttcttgtt tgctttgtgt tgctggaagc ttggcggtga
    82441 taatcctgag tctgagggac ttgactctct tcgaacgatg tatggtgatg cgggcgaatc
    82501 agctgttgcc agtgaagaag aaaagcataa cctgtcttat tggcaactca tctggaaata
    82561 cgttttttgt aacccgtcgc tcttacttgt tgctgctgtc aatgtggccc tttattttgt
    82621 tcgttttggg attgaagact ggatgccgat ctacttgtca caagtagcca atatgtcaga
    82681 ggcccatatt cattttgcga tttcaatgtt agagtgggta gctattccag gctcgctggt
    82741 atttgcgtgg ttagcggttc gttatcctaa taaaatggcc aagattgggg ctattgggct
    82801 ttttgtgtta gcggctattg tgtttgtcta tgaacgcttg actgccacag gtgctccaaa
    82861 ctatttcttg ttgcttgtta ttgcaggtat tttagggtca ttgatttatg gcccacagtt
    82921 gatcgtgaat attttaacaa tcaactttgt tcctttaaac gttgcaggaa cagcgattgg
    82981 ttttgtagga gtaacagctt atctcatcgg caatatggga gcaaactggc tgatgccgat
    83041 tttggcagat ggttttggct ggttttggtc atatattgtc gttgcagcct tatctgcttt
    83101 ttcagcggtt ggttatttaa ttttagccaa acgtgaggaa gaaatcatca aagattagct
    83161 aggcaaatgc ctaagaaaga cagacttatt gctgaagtcc tgtctttttt agtcatcaca
    83221 agccgcaagt aacactataa aagacaagaa aatgctaggg tgtttcagga aaaaaagaga
    83281 aaatatgcta taatgagaag gtatttaaat tatatagtaa ggaaaaacaa atgacaaatt
    83341 atgccattat tttagcagcg ggcaaaggga ctcgcatgac ttctgatctc ccaaaagttc
    83401 ttcataaagt atctggacta accatgcttg agcatgtttt tcgtagtgta aaagcgatta
    83461 gtcctgaaaa atccgtgacg gttattggtc acaaatcaga aatggtacgt gctgtcttag
    83521 cagatcaatc agcctttgtc catcaaacag agcagttagg aactggccat gccgtgatga
    83581 tggcagaaac acaactagaa ggactagaag ggcatacctt ggtgattgca ggagatactc
    83641 ccttgatcac tggagaaagc ctgaagagtc tgattgattt tcatgtgaac cataaaaatg
    83701 tcgccactat tttaacagct acggctcaag atccatttgg ttatggtcgt attgttcgca
    83761 acaaagatgg cgaagtgatc aagattgttg agcaaaaaga cgccaatgag tatgagcaac
    83821 aattaaaaga aatcaataca ggaacttatg tgtttgataa caagcgtctc tttgaagcgc
    83881 tcaaatgcat cactaccaac aatgctcaag gagagtatta cctgactgat gttgtgacta
    83941 tttttagagc aaacaaagaa aaggtaggag cctatatcct gagagacttc aatgaaagtc
    84001 ttggtgttaa tgatcgtgtg gccttagcaa cagctgaaac agtgatgcgc cagcgcatta
    84061 cccaaaaaca tatggtcaat ggggtgactt tccaaaatcc tgaaaccgtt tatattgaaa
    84121 gcgatgttga gattgctcca gatgtcctta tcgaaggaaa tgtgaccttg aaagggcgta
    84181 cacatatcgg ctcaggaact gtcttgacga atggtactta tattgtggat tctgaaattg
    84241 gtgataactg tgttgttact aattcaatga tcgaatcatc tgttttagct gcaggagtta
    84301 cggttggccc ttacgcccac cttcgaccag gaacgacctt agatagggaa gtccatatcg
    84361 gtaactttgt tgaggtcaag ggttctcaca ttggtgaaaa aacaaaggct gggcatctga
    84421 cttatattgg aaacgctcag gttgggtctt cagtcaatgt tggggctgga accatcactg
    84481 tcaactacga cggccaaaac aaatatgaaa cagtcattgg agatcacgct tttattggga
    84541 gcaactcgac tctcattgca cctttggaag ttggggatca cgctttaaca gcagcaggtt
    84601 caacgatttc aaaaacggtt cctatcgata gcattgctat tggtcgtagc cgccaagtca
    84661 caaaagaagg ttatgccaag cgcctagcgc atcacccaag tcgaagcaaa taattcaaga
    84721 tctatttagt aaggaggcca ggcatgaaat ttgaagaaaa aacgcttaag agacaaacag
    84781 tttttgatgg tcatattttt aaagttgttg tggatgatgt tgaacttccc aacaatctgg
    84841 ggcaatccaa gcgagaatta atttttcatc gtggtgccgt tgctgttttg gctattactc
    84901 ctgaacgtaa gattctcctt gtcaaacaat accgtaaggc tattgaacgt gtctcatacg
    84961 agatcccagc gggtaagcta gagattggtg aggaaggctc aaagctaaaa gctgctgcac
    85021 gtgagctaga agaagaaaca gcctatacgg ggacattgac gtttttgtat gaattttata
    85081 cagcgattgg tttttgcaac gaaaaaatca cacttttctt agcgacagac ctaacacaag
    85141 ttgccaatcc caaacctcaa gacgacgatg aagttatcga ggtcttagag ttgacatatc
    85201 aagagtgcat ggacttagtc gctcaaggta aacttgctga cgctaaaacg ttgattgctt
    85261 tgcaatacta tgccttacat tttggaggtg agcagtgatg ggaaggccat tgttgaccga
    85321 tgatatcatc gaaaaagcga gacgaatgga aacatttgag tcagatgatg ctgtagactt
    85381 tgacacaaaa gtaatgacgc taccagaaaa agatgataaa gcacgcattt ataaaagccg
    85441 tcggattgaa aatgccaagc gcagccaatt gcaatctaaa ttaaatgtga ttttgatagc
    85501 tgttatgctg ttaattgcca tcttggtata tgctatcttt tatctttaaa aaaacgtaag
    85561 gaaatgatat gaaaatagga attattgctg ctatggagga ggagttgtcc ctgctcttag
    85621 caaatctttt ggatgctcaa gaacatcagg tgctttcaaa aacttactat acgggtcgtt
    85681 ttggcaagca tgagctcatt ttggtacagt caggtgttgg aaaagtgatg tctgctatga
    85741 cagttgcgat cttggttgag catttcaaag cccaagctat tatcaataca ggatcagcag
    85801 gggcagtcgc ttcacattta gcgattggag atgtggtggt tgcagatcgg ttagtgtatc
    85861 atgatgtgga tgctactgca tttggttatg cttatggtca aatggctggt caaccattat
    85921 actatgattg tgatccacag tttgtggcta tcttcaaaca agtcctaaaa cacgaaaaga
    85981 caaatggcca agttggtttg attgcaacag gagacagttt tgttgctggt caggacaaga
    86041 ttgaccagat caaaacagct tttagcgacg tgttagcagt agaaatggaa ggcgcagcta
    86101 ttgctcaagc agcacatact gcagggaaac ccttcatcgt tgttcgtgcg atgagtgata
    86161 ccgcagcgca tgatgccaat attacttttg atcaatttat tatagaagct ggcaagcgtt
    86221 cggcccagat attaatgaca tttttagaaa acttacctgt ttaactcacc ttatcgtgag
    86281 acaattagct ggataatctc tattttagga gtctggtcac ttcttgtttt gaaacctaaa
    86341 aataagaatt gcaatcactt gaccaaacgc tataataggt taagtaacga tagattacta
    86401 aaaggagtct aaaaatgaca ctaaaaaaac actattatct tctcagtctg ctagctcttg
    86461 taacggttgg tgctgccttt aacacaagcc agagtgtcag tgcacaagtt tatagcaatg
    86521 gaagatatcg tcaaggtttg actgatgaaa aatcaaagct gcaatatagt aaagacaacg
    86581 ccaaacttca attgagaaat atccttaacg gctaccaaag tgacctaggg agacactact
    86641 ctagctatta ttactacaac ctaagaaccg ttatgggact atcaaaagag caagagattg
    86701 aaaaatatta tgaagagctt aagaacaagt tacatgatat gtacaatcat tattaagtta
    86761 aaggcttaaa aatggagact agcccctcaa aaaaagaggc cacactcatt taaatttaaa
    86821 tgagtgtggc ctctttttga ggagacgcaa ggggttaaag ggctgtgaca tagagttgct
    86881 tagcaatatt ttcagggatg acaagttcct tgtcgccata acaaatcgta taggtttttg
    86941 caaaggtatc aatttgagtt aaggttagct cggtattgat actcaggtga tgtgcttcta
    87001 gatactggat taaatcaaag tggtcgtgga ttctgcttag gcgaaaccgt cccaactccg
    87061 tgatggtgtt gagagttgta gtgttcattt cgacaagagg ctgaccatag cgaggaatag
    87121 tccctccgtg tgggcagaaa tctggaaaat caaggatctt gtctaaacgg tcgataaagg
    87181 tgtctgagac agtgtgctct aagacttcag cttcttggtg cacttcttgg gtattatagc
    87241 ccagctggtg aatcaaaaat acctcaatca agcggtgttt gcggtagagg ttagcaacaa
    87301 gagcatagcc tttgtctttt agcaaatagc cttttgcttt atctttgaca atccagcctt
    87361 gtgaaatcat ttttttaatc atctctgaaa cggcaggtgc cgaaacgtgc atcttttctg
    87421 caaccatttt atttgtaatc ttgggttctt gttctccaat ttcatagata catttcaagt
    87481 aatcttcttt attaggcgtc atatgtttgg cctttctctt atttataatg attattatat
    87541 cagaattttt aggaaaaagc ttgacaaaaa gcctaaaaga ggatatcctt atagcataat
    87601 taactaaact taattaaata aataatatat cctaaggaga gaaatgatgg gaaagagaat
    87661 gagcctcatt ttgggtgctt ttttatctgt ttttctttta gtagcttgtt cgtcaactgg
    87721 cactaaaact gctaagagtg ataaattaaa agtcgtggca accaattcaa ttattgccga
    87781 catgacaaaa gctattgctg gtgataaaat cgatctgcac agcattgtgc caatcggtca
    87841 agaccctcat gagtacgaac cattaccaga agatgttgaa aaaacaagta atgctgatgt
    87901 gattttctat aatggtatca atctagaaga tggtgggcaa gcttggttca ccaaactagt
    87961 gaaaaatgct caaaaaacga aaaacaaaga ttactttgcc gtgtctgatg gcattgatgt
    88021 gatttacttg gaaggtgcaa gcgaaaaagg aaaagaagat ccacatgctt ggttaaatct
    88081 cgaaaacgga atcatttatt caaaaaacat tgccaaacaa ttgattgcaa aggatcctaa
    88141 aaacaaagaa acttatgaaa agaacctaaa agcttatgtg gctaaattgg aaaaactaga
    88201 caaagaagcc aaatcaaaat ttgatgctat tgcagaaaat aaaaaattga ttgtgactag
    88261 tgaaggctgc ttcaagtact tttcaaaagc ttacggtgtc ccatctgctt atatctggga
    88321 aattaacacc gaagaagaag gaacaccaga tcaaatttca tcattgattg aaaaactaaa
    88381 agtcatcaag ccatctgcgc tttttgtaga gtcaagtgtc gatagacgcc ctatggaaac
    88441 cgtttctaaa gatagtggta ttcctattta ttctgagatc tttacagatt caattgctaa
    88501 aaaaggtaaa cctggcgata gttattatgc tatgatgaaa tggaaccttg acaaaatttc
    88561 tgaaggtcta gcaaaataag ataacaataa agcacagcga ttttagtgtt gtgctttgtt
    88621 ttatttatgt aaaggagaca aaatgattac aactaacaat ctttgtgtga cctacgatgg
    88681 caacagtaat gctttagaag cgattaatgt gacaattgaa ggtccttcta tcgttggtat
    88741 tattggtcct aatggagctg gaaaatcaac ctttatgaaa gctattttaa atcttattga
    88801 ttatcaaggt cacgtaacgg ttgatggcaa agatggtcgt aagcttgggc atacagtagc
    88861 ttacgtagaa caacgaagca tgattgacta taattttcct attactgtta aagaatgtgt
    88921 ggcgctaggg acttatagta aattaggcct ttttcgccga gtaggaaaaa aacaatttga
    88981 gcaggttgat aaggttctca aacaagttgg tttagaagac tttggccatc gaccgataaa
    89041 atccttatct ggtggtcagt ttcagcggat gttggttgcg cgttgcttga ttcaagaatc
    89101 agactatatt ttcttagatg aaccgtttgt tggcattgac tcggtcagcg aaaaaatcat
    89161 tgtagatctt ttgaaagagc tcaaaatggc tggcaaaacg attttaattg tacatcatga
    89221 tttgagcaaa gtagagcatt attttgacaa actcatgatt ttaaataaac atttggtggc
    89281 ttatggcaac gtttgtgagg tatttactgt tgataccttg tcaaaagcct atggcaatca
    89341 tttgatttta ggaaaggaga tggtgtaaat gtctatgaaa ttttttgagg gcttgatgtc
    89401 ataccacttt ttacaaaatg cactgataac ggctgtagtc attggtatcg tctcaggtgc
    89461 tgtagggtgt tttattatcc ttaggtcaat gtctcttatg ggtgatgcca tctcacacgc
    89521 tgttttacca ggggttgctt tgtcatttat tttaggagtc aattttttta ttggagcgat
    89581 tatttttggg ttattagctt ctgttattat tacttatatc aaggaaaact ctgtcattaa
    89641 aggagatacg gctattggta tcacctttag ctcttttttg gcactgggag ttatcttgat
    89701 aggggtagcc aatagttcga cggacttatt tcatattttg tttgggaata ttttagctgt
    89761 gcaagatagc gataagtgga ttactattgg tgtttcgatt tttgttttag tggttattag
    89821 tctctttttc aaagaactat tattaacatc atttgatcct atcttagcca aatcaatggg
    89881 tgtgaaggtc aatgcgtatc attatttgtt gatggtccta ttaactttag tggctgttac
    89941 ggcgatgcaa agcgtgggta ctatcttgat tgttgcctta ctgattacgc cagcagcgac
    90001 agcttattta tatgctaata gcttaaaagt aatgttagtg atgtcatctt tactaggtgc
    90061 tttagcatcg gttttagggc tttatttggg ctataccttt aatgttgccg cagggtcaag
    90121 tatcgtactg acttctgcga tgatgttttt gatcagtttc tttgtttcac ccaagcaagg
    90181 ctacctcaaa agatggatgc aaaaaaaaga aaaaacacct taaacttttc gctttaaaca
    90241 ccttagtggt ttgcaaatag tggcaaataa catcaaaggg tgttttttat atgtcatcaa
    90301 aagaccataa aaaaccttat caaaccaagg tatttagcct attatctgat aaggtttttt
    90361 aagcatgatt tagtttttaa agcgataatc tttgacaatg tcaattgagg taatcgtaat
    90421 gtcttgtttt ggtttatcat tttggttgat agaagtcgcg gcaattttat cgacaacatc
    90481 cataccatca atgacttgac caaatacagt ataaccgcca tctaagcttg gattgccgcc
    90541 atgctcatag gcagagatga taggttttgg gtagttggta cttgataatc ccttgctttg
    90601 atttttcttg ttttggttga tataaaattg gctaccgtta gtattagcgc cagcatttgc
    90661 catggcaaga gcaccgcgaa tatgatataa aaatggagag atttcgttga caaagccatt
    90721 gccagcatct tttttaggat ccttgccctt ccaaatcgat tcaccacctg tgccatctcc
    90781 tttggggtca cctgattgaa tcataaagtc gttgatcaca cgatggaagg taaggttatc
    90841 atagtagcct tttttagcat gggtgaggaa gttctcaaca gctaagggag catattttgg
    90901 gaataactta agggtgatgt ccccttgact tgtcctcatt acgaccttag cttcttcttt
    90961 gccgacttct ttggttagtt gtggaaattg gctagcatca gctttgagag ctttttgaat
    91021 gctttcttca taggctttag aagctgcttc gctttcttct ttggcagttt tttcatcaat
    91081 gtatttatcg ccttttatag cgcggtcaac agattcacaa gcactcaaac taagtaaact
    91141 aatggctact aaactgagag ataataattt tttcatgtct actcctaaga atgattttct
    91201 ttattttatc ataaaatgca acagaaaata gtagtaaaga gttaaaaacg cctatttttg
    91261 tgttttatga tctaaccttg gttaaaaggc tgctacgact gttattatag cacaagatgc
    91321 tatagaaaaa cttaaaacac cttggttttt tagagctatt tcctaatagt taaaaaatgg
    91381 tataatagtg ttatggttaa aagaaatcaa agaagaaaaa gtgcgcctaa gaagtgtctg
    91441 acaaaagcag aagtggaaaa gcaacgtgcc attaagagga tgattttatc tgttttaatg
    91501 gctttgttgc ttatttttgc gatgcttcgc ttgggcgtct ttggcgtgac aacttataat
    91561 atgattcgtt ttttggtggg tagtttagcc tatccgttta tgtttgcctg gttaatttac
    91621 ttattttgtt ttaaatggtt acggcaaaaa gatggaatga ttgcgggagt tgttattgcc
    91681 tttttgggat tgctagttga gtggcacgcc ttcttatttg cgatgcctag gatgcttgat
    91741 caagatattt ttctaggcac tgctcggcta attacaagag atttactagc cctgcgcgtg
    91801 actgaatttg ttggtggagg aatgcttggt gcattacttt ataaacccat agccttttta
    91861 ttttcgaata tcggctctta ctttattggt tttttgttta tcttattagg attatttcta
    91921 atgacgcctt gggatatcta tgatgtgagt cactttgtga aagaggctgt tgataaacta
    91981 gcagtggctt atcaggaaaa taaagaaaag cggttcatca aacgagaaga gcaccgctta
    92041 caagctgaaa aagaggcttt agagaaacaa gcacaggagg aagaaaaacg tctagcagaa
    92101 ttgacggttg atcctgagac gggagagatt gttgaggata gtcagtctca agtcagctat
    92161 gatttggctg aggatatgcc aaaagagcca gagattcttg cttatgatag tcacctcaaa
    92221 gacgatgagg caagcttatt tgaccaagaa gacttggctt acgctcatga ggaaattggg
    92281 gcttatgact ctttatctgc tttagcatct tctgaagatg agatggatat ggatgaacct
    92341 gttgatgttg atttcacgcc aaaaacccat cttctttata aacttccaac gatagattta
    92401 tttgcaccag ataagcccaa aaaccagtcc aaagagaaaa acttagtccg caaaaatatc
    92461 aaggtgcttg aagatacctt ccaaagtttt gggattgatg tcaaggtaga gcgagcagaa
    92521 atcgggcctt ccgtcaccaa atatgaaatc aagccagctg tcggggtccg agttaatcgt
    92581 atttcaaatc ttgctgatga tttggcactt gctctggctg ctaaagatgt tcgtatagaa
    92641 gcaccaattc ctggaaaatc cttaataggt attgaagttc ctaactcaga aattgcaacg
    92701 gtttctttcc gcgaactttg ggaacaatct gatgccaatc ctgaaaacct tttagaagta
    92761 ccactaggta aagctgttaa tggtaacgct cgcagtttta acttagctag aatgccgcat
    92821 cttttggtag ctggttcaac tggttcaggt aaatcggttg ctgttaatgg cattatttca
    92881 agtattttga tgaaggcacg tccagaccaa gtgaaatttt tgatggtcga ccctaagatg
    92941 gttgagttgt ctgtttataa tgatattccc catttgctga ttccagtagt gaccaatcct
    93001 cgtaaagcca gcaaggcgtt gcaaaaagtg gttgatgaga tggaaaatcg ctatgaactc
    93061 tttagtaaag tcggggttcg aaatattgct ggttacaatg caaaagttga ggattacaat
    93121 aggcaatctg agcaaaaaca aatgccttta ccattgattg tggttattgt ggatgagtta
    93181 gctgatttga tgatggtggc tagtaaagaa gtggaagacg ctattatccg tctggggcaa
    93241 aaggcgcgtg cggcaggtat tcacatgatt cttgcaaccc aaagaccatc tgtggatgtt
    93301 atttctggac tgattaaggc caatgtgcca tcccgtattg catttgccgt atcttcagga
    93361 acagatagtc gaacgattct ggatgaaaat ggcgctgaaa agctcttagg acgtggagat
    93421 atgctcttta agccgattga tgaaaatcac cctgttcgtc tgcaagggtc tttcatctca
    93481 gatgatgatg tggagcgtat tgtcaacttt atcaaagacc aagctgaagc ggattatgat
    93541 gatgcctttg atcctggtga agttagcgac aatgatcctg gtttttctgg aaatggcgga
    93601 gctgctgaag gtgatcctct ttttgaagaa gcaaaagcct tggtcttaga aacacaaaaa
    93661 gctagtgcct caatgattca aaggcgtttg tcggttggat ttaatcgtgc cacgcgcttg
    93721 atggatgaat tggaagaagc aggtgttatc ggtccagcag aaggaaccaa acctcgtaag
    93781 gtattgcaga caaactaaaa gaacctgacg tctcatgatg agatgtcagg ttcttttttt
    93841 gtgatgtcaa gccagttgat gagatgccta tgctaatgta aaaataaaga taactagaat
    93901 caggtagaaa ataacggtga ctaaaaagcc aactcgccaa aatagcttca taaagcgatg
    93961 gtaagaaaac gactgagttc ggatgactag cagtagtgaa atgacgatgg ctagcagcga
    94021 catgataata aggtaataag gcagtaaatt atgggtgaaa aattttcctg agacaagcac
    94081 aatttctatc gcaaaaagta aaagtgcgac atctggaaat ttaaatccct ttttattaag
    94141 tttaaataaa ggggttacaa tcatggcaaa aagaggcgtt actatcaaga aagctaaggc
    94201 agttaattta tagatcatca taggtctatt ttatactcaa atcccttact tgtaaactga
    94261 tacttacctg ttgtgataga aaatgatctt tgagagggaa agcgcctact tcaatttaaa
    94321 cattacaaaa ggcatcagct attttaacgt aagtgtctag agttttggga aacgtaaaat
    94381 taaatacctt atagcttaag agaacgagaa attcgttctc ttttttcatt gtctaaaact
    94441 agtgaaagga aaaatataga tgtcaaataa tttagaaata gttatggata ttgaaactct
    94501 agacatattt gaagtgatag atcttgatga agagaaagaa gtgactgttt cagattctga
    94561 aacttttcct aaagaagaga aagcatcccc atatgatgat ctaaacagaa tttggttaag
    94621 aaatggttat tattacaaac cttctagtct actttgggaa gttattgaaa atggtattat
    94681 tcacgatttg agtcctagaa ataaacatgg tacttatccc tactaccaac attcacgaga
    94741 tggaacctgg ggtcatgtca agcaactcac acaagaagaa gctttatggc ttactttgga
    94801 actgaatcca gacttgatga attatgtgta ggagattcat tgtgaagagt agagacgatg
    94861 agattcttta tactgcacgg ctatatctat ttggtgtgat tccattgtgg aaagtaaagc
    94921 acacaaagca agagtggaag agacgtatac ttttaaaacc cagtaataag cttattgaac
    94981 ttcagtttat tgaagctgaa gaggaggaaa agaagtgaca caacacctgc tgaactgtta
    95041 tccagagtat tttgaggcca ttatggatgg gacaaagaca tttgaatgtc gctataacga
    95101 tagagatttt aaagttggcg atgaactgtt actgagagaa tatgatccca aaaaaggata
    95161 tacctatccc tatcgctgta ttgttagaaa aataacttat attctatcgg actttattgg
    95221 tctaaaagat ggttatgtaa ttttaggagt aacaaatgag cccattgatt atttttaaca
    95281 ttagttttgc ttttgtcttc taccccatgt ttatcagtaa ctatcacaaa agagagcctt
    95341 atttgttaga tttgtttctc tttgtcataa atattctggc atctctatat actattttca
    95401 attattttga gttgctgaag tgaggacttg ttatgtctaa tcgactaaaa gaactacgaa
    95461 aagagaaagg attaactcag gctgagttag cacaaattat caatactaat caatctcaat
    95521 atggcaaata cgaaaacgga aagaccaatc ttagccttga aaacgccaaa atcctagcgg
    95581 attattttgg tgtttctcca gcatatttat tggggttgga aaccgagttt gaacctgtgg
    95641 aatctagaga gactcaattt caaatgctag tcaaggacag aaaattatcc ttgagagaaa
    95701 taagcgagga tacgggaata aactactcta ccattggaaa ctataatcaa ggaactagaa
    95761 tacctaatgc taggaatgct gcgatattag ccgattattt tagagtatca gtcggatatc
    95821 tattgggata tgaaaaagag cctaacttaa taaaagcaga acccttaatt ctgacaaaat
    95881 tgattcaaga gttatcttct atcaattacc aaaaagaaga gattctacaa gtatatttag
    95941 aattggctaa aaaagaacag gctattctca aaaagattaa ggagagaatt tgatgataga
    96001 taacgatatt caaatcaatg aaggagatca agatgctaca aaatcgttta aagcaattaa
    96061 tgcttaaaaa gcataaaact gtagaacaag ttagtcagga aacagggatt aagaaaggtt
    96121 ccctagaaat gtacattcta ggaaaagaca ttatgactga tgatttggat attctgactc
    96181 gctattttca aaccaacagt ccttatctca ctggtatttg gggtattgca gctgatgaga
    96241 aacatgttac acatttcagg aagctattca aagatagtag ttattatttc atgccggatg
    96301 ttagtgatat ttttgaagat ttagataact gtttctataa tttttggata caatctctgg
    96361 aatttacagt cttagaaaat aatggcagag cggaacgttt ctttaaggaa ttaaccttcc
    96421 acccacagga tgactgtgtt tttattaccg tctcagacag atatgttatt gaagcactag
    96481 aatcttacaa ccaaatcatt cgctatcatt atcctgaagg tggagattat acaccagtct
    96541 taatattcaa agggaaggct ataaagtaac acaatttagt atgtgagggt ttatcaacga
    96601 ataagatacc aaataggatt aaagaattaa ggaaacaaaa gggagtaaca cttaatgatt
    96661 tatcacttgc tacaggtttc actactagtt ctataagtcg atgggaagaa ggtagccgag
    96721 gttttgataa agagaaagcg attcttatgg cgaaaatatt agaagtcaaa ccttcagaat
    96781 tatttatttc agatgaaaat aatttccaaa cgtattggaa tacggaaaaa aatattacct
    96841 ttaggggtga taaatatatt gtttcaatca tgcgcaaagg gaaaaagtat tcgaggtcat
    96901 ttgataaatt agaggaagcc atcagacata gagatattat tttaaaggac tacaaagaga
    96961 caggtatact tcctaaaacg cgtacagagg aaataatttc aagttatcga gaattaattg
    97021 gtaaaaaatt tcgaagatta actgttattg atatagttgg tccgaaaaag aaaaaagatg
    97081 tcaaacgtac ctacacttac ctattatgtc attgtgattg tgggaatact tgtgaggtcg
    97141 agatttttaa tttgcttaag ggaactattt tgtcttgtgg ttgtcttgcc ttagagaaaa
    97201 gtcaggaaat aggaaaaaga tttggaaaag atagtgagac tagtgaaaaa gcgagggttt
    97261 caaatatctt gaattctaat ccacgaaaaa caaataagac tacacagata aaaaatatta
    97321 catacagtcc taaattaaaa tcatatagag tacaaatcac aaggaggggc gttcactata
    97381 caaagcgttt tcctagttta gctgaagcta ttgattataa agaagtcgta ttgaatcagt
    97441 tagacaaaga tgttcgacaa aaacaagtaa agaaatagaa taaaaactta gttttgaaat
    97501 actaagagtg gttaagagga agaagacatg aaaccaaaac aatcagcagt tgctaaatta
    97561 acaaagaata tgatggtagt agatatcatg aaacaaacag gctggtcacg agacagagct
    97621 cttgctgcag tggaggaact ggaagaacaa caactaatcc acttcctgtc gcaaggagga
    97681 atgagacttc aagtgattgg aggactgtaa tggctgatat tacgattgat caattagcaa
    97741 cccagacctt ttaccaggtt ccagaaatat tttttacacg tatccaacac aatgaagacg
    97801 gctatgtcaa gttgacaagt ccctatgtta gtctctcatc agatgctaaa ttagcctatg
    97861 gtgctttata taaccgctgt aaattgagta ttagttcatt ccaaaaaggc aatagagatt
    97921 atgtagacga aaatggagcg gtattcttaa tttttacggt aactgattta atgttactcc
    97981 ttgataaggg aaagatgaaa gtcacgcaga ttaagaagga cttacaggaa catggcctct
    98041 tgcgtgaagt acgacaaggc cttaataagc ccaataggct ttatcttcaa ctggtggatt
    98101 ctagtttgga agtggcagaa tactatgatg cagagggaga attatttaag aaagtcaatg
    98161 ctttcggcaa ggtgattttc caaaaagaag atatttctca aaaaactgct gaaacccttg
    98221 gtaatagcgg aagtccgttt ttcggacgtc cgaaaagtgg acgtcaaaaa gtccataaaa
    98281 tggacgcaat aaagacagag aagagtcaga cagagtctga cgatactaat cgataccagg
    98341 acgaaatccc attatccact ctttcggatt ctgatgcttt tcaaatgggc cgacatggtt
    98401 ttctctccac ccaaaccatt cagcgactca gtttgtttgg caaagaagct aaactccttg
    98461 aaaacaaaat ctaccaagcc aagcgtcaga ttgaaaaaga ctatagtcac ctcttacaga
    98521 atcaggaaat aatttacggg gaggtctggt cgcaggaact ggaacgtgag gtggacaagc
    98581 tcatcttcaa aatcaaaaca ggtgagaatg aaggcaagcc aatcaaaaat atcccaggct
    98641 atttctacaa gatgatggtg cacttttgga agatggcttt gttaattgag aaggaacaag
    98701 gattcgtgtc acttgctaac cagagtgaat ataccaagca atattctgaa gaatgtccaa
    98761 gtctaatcgc ctattattat ccagataaac tatcagaaag caaactaaat cagtatttaa
    98821 ccgcactaca aatggaggta tgacatgtta gacaagccat ctaggaatag tcctcgagat
    98881 aagcttaaaa atcatcttaa ggcctgtcaa actcctctta aaaattatcc cctaaaggca
    98941 gtttttctgg cagttatctt tatagctatc gtcttttctt tcttttctca aatactaata
    99001 tccctaaagg ctatgggctt cactacctta tcgttactga tactgttagt cttgggttat
    99061 ccatgtcatc ttcaaagttt atatcatgat ttaaaactta gtatctatca atatcagcag
    99121 gataaaattg attttttcaa aacgtatggt gaaaagcaag aagacgtgat tgatgacata
    99181 cgaataatct atgaaactga taatacggta acggtacagt ttatctatca ggggcagcct
    99241 tcgcaactat ccttgtctaa gggtgctatt ccccaatcat acgctaatca acaattagta
    99301 gttatagcaa gatgtcgagc gattgctaaa gagcacttat cagcgtatct catcctgttt
    99361 gaaacaagag atttagctca aaagtatcag acaatactca aacacccgat aataacagaa
    99421 ggtttacttt cagacaatga tattcttcaa ttgagtgaag cgcctgataa accgatggta
    99481 tcgtttcagc tagcactaat cacgcaacca aaagaaagtg agacaagcaa atgattatca
    99541 aagaacgaaa tggatttttg accattccca aatctatctt tagcttacca ccagaggaaa
    99601 aaactcaagc tcttaaagag cttgaggaag agatggaaca gcacaaagcg aaagggggtg
    99661 actccacttg acaactatca ctcaaaatag agtaaaggag ctacgtaaac aggctggcct
    99721 ttcccaacaa gcattagcgg atcaaattgg cgttatgcgt aaaacgatct cgcattggga
    99781 attagggaac cataggatat caacagataa tgctaaaaag ctctcacagt tctttcaggt
    99841 atcgatagat gacctactaa acaatcatgc aaggagaagc caatgaataa tacaaactta
    99901 attggtcgtc tgactaaaaa ggctgagcta tatcaaacgc cagataagaa gacctatgcc
    99961 cgatttacaa tagcgattaa tcgcaaaaag aaagcaggcg ggtcaggaag tgaggccgat
   100021 ttcattccct gcatcatctg gggaaaagct gctgaaaact tagtgaactg gacggataag
   100081 ggaacactca tcagtctaga gggagaactg cgaactcgca actatgaaaa agatggtcaa
   100141 cgtcattttg tcatggaggt gtggtcaacc tttttccaag tcttatcaaa gccagctaat
   100201 gacaactaat cactctaaga acaaggagaa catcatgaaa caagtaaaag tattaacagg
   100261 aatcgcagtc gcagctctat ctacaggcac aggtcttgtg caggcagatg atttatcaaa
   100321 tacaagacca gctaaagcag ctgaagttgt gacacatacg gaagtgacag aaaatcaagt
   100381 agctgacgct aaaacaaaag ctgatgaggc aacgaaagcc gttaaggatc aggaagctac
   100441 ggttaaggct attgaggcag aaaaatctca agcacaacaa tctttagtta atgcgacaac
   100501 agcagttaat gataccgaaa agttagccag tgaagcgaca ccagatggtc taacaaaagc
   100561 ccaagatgag gctgaggcta gtcaaagcgc tgttactgat gcacaagcac agcttgaagc
   100621 agctcaagag gctgaatcaa cagcccaaac agcagttgac catcagaaag aaacagtcgc
   100681 caaagcgtct caagcagttg ttgagaaaga agctacagtg acaagtgcta ctcaagctgt
   100741 taatcaagcc aaggcagctc tcacgacaac taatcaagct gttgatgtca gtgcagcgga
   100801 agaaaaagtg ttagaggctc aagaagcggt tacgaaagca gaaacacaag tttctcaggc
   100861 tcaggaagca gatgcaaaac atgggtctga tgtaagccat gctaaagaag agcttgacct
   100921 taagtttcaa gagttagcag aaaaacaaac aactttagag caagtcatgg ctgcgattga
   100981 agcagagcgt cttactaagt cggttgaaaa tggcacttac tttaaccaaa gagataacga
   101041 gtggcaaaaa gcctacggtg ggaagacctt tgcggcgaca ggatgtgtgc cagcttctct
   101101 tgctatggcc ttctcagaat tagtagggag acacattagt cctctggaag tcgcagatta
   101161 cttataccaa attggtgagt ttaataatgg tcgttttgat gggacctcaa gtattggtgc
   101221 tatgaaagcg gctgaacatt ttggcttagt tccaactgtt ttaaaaacct tagatcaagt
   101281 gcaaacagcg ctacaagatg gacactatgt cattaattcc attcaacacc atgagaagtt
   101341 tgcgccttta tcttggggat ggtcagctag tcatgacgta gcactaagag gttatcaaga
   101401 tggcaacact tatgtctatg atccttacaa tcgcaataat attggctatc ataatttagc
   101461 tgatttatgg aatcatcaaa gtcataaccc agaagatgtg gatggggttg gtgttccctt
   101521 tattagcttg atgacgaaac agatggctca attaatggca gaaaaagtta cggttaatca
   101581 agcggtacaa ttggctaacc aagctttaac tgaagcccaa gcaaatgtga cagccttaga
   101641 acaagtcgcg tctcaaacct cacaagcaaa agaccaatta gctgcagcta aggctaactt
   101701 agtcacagcc aaagatatgc tggataaggc gaaacaaaga gctaaattaa cagaacaaga
   101761 cctagaaacg aaaacagcta ttcttaagca agctcaagaa catctaaccc ttaaacaaga
   101821 tgacctagct aaagctcaaa gggtgctagc agctcaagag accagcttag aacagttaac
   101881 tcaagccctc tcattagctc aagccaatct tggccgtgcg acaaaagcag ttgaacaggc
   101941 taaggctgac ttcacccaaa aacaggctta tgtgacgaat cttaagcaag tgacaaaact
   102001 gagacaagaa agtcaagaca aagtaaacca agctaaggcg gttctcagtg aagcaagtgc
   102061 tcgtttagaa cgagaacttg agaccttaaa aaccttgcaa gccaaagagg ctgacctaac
   102121 agcacagtat caagctatct ttaaagccta tcaagctgtt ttagctgcga aacaccactc
   102181 acaattggct gaaagcaaag ctaagcttga agctaaggga gaagaagctg ttcctgtggt
   102241 caatgaagta ggacatgtaa cggattatgt gtctgggaca acacagcttg ctgatggtgt
   102301 agcggtgaga acagaagaaa catcatcaaa aacaatgaac acttctcttg ttagcgtaca
   102361 accgatggac aagcaaggtc atcaaagggt tcttggtgcc actacttctc aaagtagcct
   102421 tcctcagaca ggtgagcagt ctgtatcgct tttaagcctg ttaggaatga ctctcgtctc
   102481 tctacttggc ctagtctctg ttaaaaagaa agccgagtaa actaatgaac tgagcagttt
   102541 atctgctcca accagcaact gctagggggc ttcatccctt agtcttcgcc tacagttgtt
   102601 gcttcgagcg ggtaaacgag ctcatagtcc tttgtcaact aaataccccc actgtcctga
   102661 tcagcgtggt ctaagcataa aagaaaaaag ggggcggtgt ttgtaactag aaaaggatag
   102721 ctagtgctga ccacttaacg taaagccaga gtttgacctg tcctctaagg cgaaggagtt
   102781 tgcggtacct agactaaaaa ccgtgtgtca aaactaccga gaagaggtga cagacctctt
   102841 ccagcatggc tgttcatttc agcctattaa catcaaggag aaaccaatga ttgatgaaaa
   102901 tgaaacagtc gtcaccctaa gtgacttaaa acaattagga aaacaaggag gcgctacagc
   102961 gctcttagaa gatgggacac tgctcactct aagaggaaga catgcgactc gaaggacaaa
   103021 agggtatgtg gacggcatcc tcaaagagat cgatgtcatt atcccttacc caaagatttt
   103081 aaaccagata cgaaccatca aatctcaaaa tactttagtg gctcgtagaa tcaaccgaca
   103141 aagcccacta cgtttaaccg gtagagggta tcaccgaaaa ggaaaggaat aacgcttatg
   103201 acaaaaaaac aattacttag tgtcctcaca gcgaccacag tggccctact cacaacctct
   103261 cttgcttacg cagatgagac cccagtgcca gtggatccga ctgctccttc aacggaagtg
   103321 gtcactcctg cgcctgctca acctgagaaa ctaccagaca cctcaaaacc agcagagcca
   103381 gaaactccaa aagaagaacg accagctcct gtggatccga ccaccccatc aactggtaaa
   103441 gaagacaaac cagaaacgcc aagtgtacct gaaacaccta aagaggaaac aaagcctaaa
   103501 gaagaagtaa cacctgaaac acctaaatct agcgaagaca agaaaaaaga agagcttgtc
   103561 ccagataatg tctcaaaaga cattattgaa aaggtggata ccacgacagg tgaagtggtc
   103621 tttaaaccca tcccagtcac accagacaaa acagttatcg gtactaagga tagtcaggtg
   103681 attattcgtg accaagcagg ccggacacaa gtcgttaccc ctgagagcct tggtggccac
   103741 gttaacccta atgggacagt aaccattaca gatagtacag gcgctaaaaa gacgctacca
   103801 aagacaggtg ataaacaaag cgtgcttggt tacttgggca tgatgttagt ctcagcctta
   103861 ggttacgctg tcaagaaaaa agtatcgcac taattacatg acctgggatc gtcacaaaaa
   103921 gcaacctaga agagagatga gaaaataaca tgaaacaaat gaaaacgaaa ggacacggct
   103981 atttccgtaa atccaaagcc tacggtttag ttccagttat tgctttgggg agcctagttc
   104041 ttatgggcac aacaagtgtt tctgcggatg acgtaactcc tttaaatcca gcgactaact
   104101 taacaacgct acaaacacct ccagcagctg atcaaacaca gttagctcat caagctggcc
   104161 agcagtcagg ggagttggta tcagaggtga gcagtaccga atgggataat gctgtcacaa
   104221 cagctcaaaa agcaggtgtt actgtcaaac agtctgagaa ggtcacgcat gatagcttat
   104281 catctgcgca agccgattta gagaaacaaa ctcaagctgt cacagaagct acaactaagc
   104341 aagaagctaa tacaactgct attaatcaag cagtttcgga aaataaagct attgatcaag
   104401 ctaatcgtga tgaaaaagct agagttgacg ctcttaatac taaagaggaa gctgatacca
   104461 aagctaaaaa tgaagctggt caagcccaag tagatgcaca aaacaaacaa gcccaagaag
   104521 cagctgatgc catgaatgcc caattaaagg cagactatga ggccaagtta actgaaatcg
   104581 agcgactcaa ggctgaaaat gaagccatcc gtcaacgcaa ccaacaagct agtcaagcga
   104641 ctcatcaagc caatcaagca gcccaagctg cctatcaaga aaagctagca gagattgagc
   104701 gcatcaaagc cgaaaatgcc accattcgtg atcgtaatgc taaggctcaa caagaagcag
   104761 agcgtcaaaa ccaagcgctc caagcagctt atgaagcaaa attggcagaa atcaagcaga
   104821 ttgaatcaga aaatgaagct atccgtaaac gtaatgaaca agcaggtcaa gcgacgaatc
   104881 aaacgaatca agcagctcaa gtagaatacc aacaaaaatt agcggagatt gagcgcatta
   104941 aagctgagaa tgccgccatt cgtgatcgta atgctaaggc ccaacaagaa gcagaacgtc
   105001 aaagccaagc gctccaagca gcttatgaag caaaattggc agaaatcaag cagattgaat
   105061 cagagaatgc tgctattcgt cagcgtaatg aacaagcagg tcaaacgacg aatcaaacga
   105121 atcaagcggc tcaagctgcc tatcaagaaa agctagcaga gattgagcgt attaacgccg
   105181 agaatgccgc cattcgcgat cgtaatgcta aggctcgaca agaagcagag cgtcaaaacc
   105241 aacagttaaa aactacttat gaagcaaaat taacagccta ccaacaagct
//
LOCUS       DATWVB010000002       103261 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.002, whole genome shotgun sequence.
ACCESSION   DATWVB010000002 DATWVB010000000
VERSION     DATWVB010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 103261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 103261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..103261
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.002"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(702..1250)
                     /gene="raiA"
                     /locus_tag="VCX65_000109"
     CDS             complement(702..1250)
                     /gene="raiA"
                     /locus_tag="VCX65_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEP5052609.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
     gene            complement(1330..1995)
                     /locus_tag="VCX65_000110"
     CDS             complement(1330..1995)
                     /locus_tag="VCX65_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEP5052610.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            complement(1967..3292)
                     /locus_tag="VCX65_000111"
     CDS             complement(1967..3292)
                     /locus_tag="VCX65_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP5052611.1"
                     /translation="MESIENSYGRLLLESQLPDSAKQLAQPLKSVVISRGKMICQRCH
                     YQLDEEARLPNGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWSGQLTAYQEMI
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFNNRPLVIPKFIRSFN
                     LFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN"
     gene            3348..3980
                     /locus_tag="VCX65_000112"
     CDS             3348..3980
                     /locus_tag="VCX65_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEP5052612.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNSQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            4108..5049
                     /gene="cysK"
                     /locus_tag="VCX65_000113"
     CDS             4108..5049
                     /gene="cysK"
                     /locus_tag="VCX65_000113"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEP5052613.1"
                     /translation="MTKIYKTITELVGQTPIIKLNCLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAEAEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKASPETVIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(5067..5444)
                     /locus_tag="VCX65_000114"
     CDS             complement(5067..5444)
                     /locus_tag="VCX65_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEP5052614.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKPSLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(5444..6844)
                     /locus_tag="VCX65_000115"
     CDS             complement(5444..6844)
                     /locus_tag="VCX65_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEP5052615.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPLLQEKADFITKKVKEDGILYALEELGLIDKELQFPQL
                     DLPNHKGPKATIKTNHGDMTLVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPAPIAASYAAIGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            complement(6881..7522)
                     /locus_tag="VCX65_000116"
     CDS             complement(6881..7522)
                     /locus_tag="VCX65_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5052616.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN"
     gene            complement(7515..8519)
                     /locus_tag="VCX65_000117"
     CDS             complement(7515..8519)
                     /locus_tag="VCX65_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP5052617.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            complement(8516..9208)
                     /locus_tag="VCX65_000118"
     CDS             complement(8516..9208)
                     /locus_tag="VCX65_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEP5052618.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            complement(9331..11229)
                     /gene="pknB"
                     /locus_tag="VCX65_000119"
     CDS             complement(9331..11229)
                     /gene="pknB"
                     /locus_tag="VCX65_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEP5052619.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIVFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSTNDSTAPGSNTELSP
                     SETTAQTP"
     gene            complement(11226..11966)
                     /locus_tag="VCX65_000120"
     CDS             complement(11226..11966)
                     /locus_tag="VCX65_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEP5052620.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            complement(12004..13326)
                     /gene="rsmB"
                     /locus_tag="VCX65_000121"
     CDS             complement(12004..13326)
                     /gene="rsmB"
                     /locus_tag="VCX65_000121"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEP5052621.1"
                     /translation="MADNWKISIRGKALLTLEHIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLIYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSDRSVAIMESLFVRSKASIRVTDPLKLEEAAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            complement(13316..14251)
                     /locus_tag="VCX65_000122"
     CDS             complement(13316..14251)
                     /locus_tag="VCX65_000122"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEP5052622.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMELGADGIITAAFGQFLPTILLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSD
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIAAGQGA
                     LSLLVVQPAGKPKMAIADFLNGLGRKLEVGDFIGR"
     gene            complement(14313..16697)
                     /locus_tag="VCX65_000123"
     CDS             complement(14313..16697)
                     /locus_tag="VCX65_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEP5052623.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFVIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKPDRDFLFEGKPSVLYSTLDREKEKIALKGIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERQIDRSEPYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTKRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECHSNSIRYYGTGTQKAFDELQGVI
                     PEARILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKQQDFEAFY
                     RYEMAIRRQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            complement(16762..17079)
                     /locus_tag="VCX65_000124"
     CDS             complement(16762..17079)
                     /locus_tag="VCX65_000124"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEP5052624.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(17095..17730)
                     /gene="gmk"
                     /locus_tag="VCX65_000125"
     CDS             complement(17095..17730)
                     /gene="gmk"
                     /locus_tag="VCX65_000125"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEP5052625.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK"
     gene            complement(17840..19447)
                     /locus_tag="VCX65_000126"
     CDS             complement(17840..19447)
                     /locus_tag="VCX65_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEP5052626.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            complement(19577..20473)
                     /locus_tag="VCX65_000127"
     CDS             complement(19577..20473)
                     /locus_tag="VCX65_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP5052627.1"
                     /translation="MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRE
                     NVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLKGSISIGIPPL
                     ILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
                     TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVLEACERHQVR
                     PNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQFKDIKCILMERPISWRVVLTRL
                     RKKSYSEIEAYIMDDLLQSFFK"
     gene            20674..21861
                     /locus_tag="VCX65_000128"
     CDS             20674..21861
                     /locus_tag="VCX65_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEP5052628.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            21885..22535
                     /locus_tag="VCX65_000129"
     CDS             21885..22535
                     /locus_tag="VCX65_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEP5052629.1"
                     /translation="MCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDTLVEKGVK
                     DLTLICNDAGFPDKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTL
                     AERIRSGGFGLGGFLTPTGIGTEVAKGKEVITVDGKDYLLEKPLKADIALIFANKADK
                     NGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA"
     gene            22537..23196
                     /locus_tag="VCX65_000130"
     CDS             22537..23196
                     /locus_tag="VCX65_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEP5052630.1"
                     /translation="MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPSIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKT
                     N"
     gene            23229..24008
                     /locus_tag="VCX65_000131"
     CDS             23229..24008
                     /locus_tag="VCX65_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEP5052631.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETFLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYTAQ"
     gene            24079..25410
                     /locus_tag="VCX65_000132"
     CDS             24079..25410
                     /locus_tag="VCX65_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEP5052632.1"
                     /translation="MEIIGSLGVLIGVIVIIYLSVKEVNIIIAAPLATSLVILFNQMD
                     PTTTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGETTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVTFGLFYMKYCLAKSMARG
                     ETYATYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     AILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIAPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIMIAFDLFS"
     gene            25484..25966
                     /locus_tag="VCX65_000133"
     CDS             25484..25966
                     /locus_tag="VCX65_000133"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEP5052633.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(26112..27581)
                     /locus_tag="VCX65_000134"
     CDS             complement(26112..27581)
                     /locus_tag="VCX65_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052634.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERGIPEPQMTKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKATRLKAAAKAFEKQYGTFYTDATKSKLKNSAFATLPDLEAALKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDVVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQAAQAQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGYQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(27595..28749)
                     /locus_tag="VCX65_000135"
     CDS             complement(27595..28749)
                     /locus_tag="VCX65_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEP5052635.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWGNYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKVNGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            complement(28812..29180)
                     /gene="rnpB"
                     /locus_tag="VCX65_000136"
     ncRNA           complement(28812..29180)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VCX65_000136"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(29194..29520)
                     /gene="gpsB"
                     /locus_tag="VCX65_000137"
     CDS             complement(29194..29520)
                     /gene="gpsB"
                     /locus_tag="VCX65_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEP5052636.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            complement(29642..30157)
                     /locus_tag="VCX65_000138"
     CDS             complement(29642..30157)
                     /locus_tag="VCX65_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEP5052637.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDRWNEKNQEVLSQFRAVDF
                     VKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLL
                     TFDRLNDMSQS"
     gene            30238..30846
                     /gene="recU"
                     /locus_tag="VCX65_000139"
     CDS             30238..30846
                     /gene="recU"
                     /locus_tag="VCX65_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEP5052638.1"
                     /translation="MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDY
                     YLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAK
                     ETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQID
                     NGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            30833..32998
                     /locus_tag="VCX65_000140"
     CDS             30833..32998
                     /locus_tag="VCX65_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP5052639.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDISNSTNTDNNSNHPSTDDKKTTH"
     gene            complement(33462..34799)
                     /gene="pepC"
                     /locus_tag="VCX65_000141"
     CDS             complement(33462..34799)
                     /gene="pepC"
                     /locus_tag="VCX65_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEP5052640.1"
                     /translation="MSALTETFTEQLFAHYEANAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQC"
     gene            complement(34984..35808)
                     /gene="nadE"
                     /locus_tag="VCX65_000142"
     CDS             complement(34984..35808)
                     /gene="nadE"
                     /locus_tag="VCX65_000142"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEP5052641.1"
                     /translation="MTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREETSDQAYQFIAVRLPYGVQADEADAQKALAFIA
                     PDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKAAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            complement(35810..37264)
                     /locus_tag="VCX65_000143"
     CDS             complement(35810..37264)
                     /locus_tag="VCX65_000143"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEP5052642.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPGNFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAMIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVRNFDAIPLLVDIFVKGELVYQLPTLSEIKTYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMTLIDNIRKDTHGKSE"
     gene            complement(37435..38814)
                     /locus_tag="VCX65_000144"
     CDS             complement(37435..38814)
                     /locus_tag="VCX65_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEP5052643.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            complement(38983..39900)
                     /gene="trxB"
                     /locus_tag="VCX65_000145"
     CDS             complement(38983..39900)
                     /gene="trxB"
                     /locus_tag="VCX65_000145"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEP5052644.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMNPVTGMVKDLEITDQEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFPS"
     gene            complement(39964..40188)
                     /locus_tag="VCX65_000146"
     CDS             complement(39964..40188)
                     /locus_tag="VCX65_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEP5052645.1"
                     /translation="MLVEIFSLYVKGLILSSLTMILICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            complement(40292..41035)
                     /locus_tag="VCX65_000147"
     CDS             complement(40292..41035)
                     /locus_tag="VCX65_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP5052646.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            complement(41035..41838)
                     /locus_tag="VCX65_000148"
     CDS             complement(41035..41838)
                     /locus_tag="VCX65_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP5052647.1"
                     /translation="MTSVFLTSGWAFYDYLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKFLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            complement(42033..43376)
                     /locus_tag="VCX65_000149"
     CDS             complement(42033..43376)
                     /locus_tag="VCX65_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP5052648.1"
                     /translation="MSFKDYHFKQYVQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHFQEEIRL
                     ANYVGGTDKLRQIEKLKGSQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERNAKKQHF"
     gene            complement(43534..44544)
                     /locus_tag="VCX65_000150"
     CDS             complement(43534..44544)
                     /locus_tag="VCX65_000150"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEP5052649.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFC
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            complement(44546..46801)
                     /locus_tag="VCX65_000151"
     CDS             complement(44546..46801)
                     /locus_tag="VCX65_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP5052650.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            complement(46805..47128)
                     /gene="ftsL"
                     /locus_tag="VCX65_000152"
     CDS             complement(46805..47128)
                     /gene="ftsL"
                     /locus_tag="VCX65_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEP5052651.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            complement(47133..48146)
                     /gene="rsmH"
                     /locus_tag="VCX65_000153"
     CDS             complement(47133..48146)
                     /gene="rsmH"
                     /locus_tag="VCX65_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEP5052652.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            complement(48170..48334)
                     /locus_tag="VCX65_000154"
     CDS             complement(48170..48334)
                     /locus_tag="VCX65_000154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052653.1"
                     /translation="MSWDKIFDIWLDNLLTDCCVIKEAKNFLQVVEILEAAAKSVLAK
                     LADSEQKEQD"
     gene            complement(48377..48598)
                     /locus_tag="VCX65_000155"
     CDS             complement(48377..48598)
                     /locus_tag="VCX65_000155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052654.1"
                     /translation="MTNEREKEEAKVALEELLHQIQVIHLELKIVRNWGYFDLFGDGM
                     LVSWIKRRKMSKVNQLLIDLQVTLQNCRR"
     gene            complement(48618..49868)
                     /locus_tag="VCX65_000156"
     CDS             complement(48618..49868)
                     /locus_tag="VCX65_000156"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEP5052655.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDMATNIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     HTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            complement(49861..50682)
                     /gene="proB"
                     /locus_tag="VCX65_000157"
     CDS             complement(49861..50682)
                     /gene="proB"
                     /locus_tag="VCX65_000157"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEP5052656.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVITQEIIASAGGAGSKF
                     GTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD"
     gene            complement(50746..52374)
                     /locus_tag="VCX65_000158"
     CDS             complement(50746..52374)
                     /locus_tag="VCX65_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5052657.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQENHPKENFKAYKSMM
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGAVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MTDGVFTDYPTIPYFKGFYDVIQAPFSTAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKAKQTKKPVNRPHQNQSLTQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGVMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLLDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     ELMYRRDYRLLDLKWQDMTQLFTRGNGQWLTMGLIFGNLIVTGVVGFGAVIIANIIQQ
                     PLLISILLSCLTLMVLGIAHLWIQKTFWKSLEKL"
     gene            complement(52379..53113)
                     /locus_tag="VCX65_000159"
     CDS             complement(52379..53113)
                     /locus_tag="VCX65_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5052658.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            complement(53147..53413)
                     /locus_tag="VCX65_000160"
     CDS             complement(53147..53413)
                     /locus_tag="VCX65_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEP5052659.1"
                     /translation="MEKKRQRLYDVIRQAYDYPENRENVALSQLLLAASNRLIKHSNP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASSV"
     gene            complement(53606..55591)
                     /gene="tkt"
                     /locus_tag="VCX65_000161"
     CDS             complement(53606..55591)
                     /gene="tkt"
                     /locus_tag="VCX65_000161"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEP5052660.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVNHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAVYEAEYPELAAEYQKAF
                     TNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNFNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLEGILIATGSEVKLAMDT
                     QEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            complement(55809..56453)
                     /gene="fsa"
                     /locus_tag="VCX65_000162"
     CDS             complement(55809..56453)
                     /gene="fsa"
                     /locus_tag="VCX65_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEP5052661.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            complement(56579..58078)
                     /locus_tag="VCX65_000163"
     CDS             complement(56579..58078)
                     /locus_tag="VCX65_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP5052662.1"
                     /translation="MKIEDLMDKERKAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYLEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMGQETDFSQQLSDDILALLVFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVYLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            complement(58068..59414)
                     /locus_tag="VCX65_000164"
     CDS             complement(58068..59414)
                     /locus_tag="VCX65_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEP5052663.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLYFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDGDLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            complement(59523..60224)
                     /locus_tag="VCX65_000165"
     CDS             complement(59523..60224)
                     /locus_tag="VCX65_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEP5052664.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAVFISGKVAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAALAVLLFQVMS"
     gene            complement(60226..62064)
                     /gene="glpO"
                     /locus_tag="VCX65_000166"
     CDS             complement(60226..62064)
                     /gene="glpO"
                     /locus_tag="VCX65_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEP5052665.1"
                     /translation="MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDETRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQI
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIDPVINEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGQQEG"
     gene            complement(62080..63606)
                     /gene="glpK"
                     /locus_tag="VCX65_000167"
     CDS             complement(62080..63606)
                     /gene="glpK"
                     /locus_tag="VCX65_000167"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEP5052666.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQLA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
                     "
     gene            complement(63966..64358)
                     /locus_tag="VCX65_000168"
     CDS             complement(63966..64358)
                     /locus_tag="VCX65_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEP5052667.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            complement(64485..64742)
                     /locus_tag="VCX65_000169"
     CDS             complement(64485..64742)
                     /locus_tag="VCX65_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEP5052668.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            complement(64896..66935)
                     /locus_tag="VCX65_000170"
     CDS             complement(64896..66935)
                     /locus_tag="VCX65_000170"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEP5052669.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVH
                     TLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQCVIVDAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGNFEAKYLDVPEEVLVTS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEDAAVATAIREHYLPDAAGGALPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYD
                     LSFDSLTYTNKADVMNFIRARVDKMMGKAAPKDIREAILASSTFVVPEMLAVAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQ
                     QLEQVFALSPVINDFFDNTMVMAEDQALKNNRVAILSDLVSKAKTIAAFNQLNTK"
     gene            complement(67313..68230)
                     /gene="glyQ"
                     /locus_tag="VCX65_000171"
     CDS             complement(67313..68230)
                     /gene="glyQ"
                     /locus_tag="VCX65_000171"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEP5052670.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDDE"
     gene            complement(68602..69135)
                     /locus_tag="VCX65_000172"
     CDS             complement(68602..69135)
                     /locus_tag="VCX65_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEP5052671.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            complement(69267..70106)
                     /locus_tag="VCX65_000173"
     CDS             complement(69267..70106)
                     /locus_tag="VCX65_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEP5052672.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGLDYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTQEDKKTIRYLSGMSAIPNPDT
                     TSF"
     gene            complement(70228..71376)
                     /gene="nagA"
                     /locus_tag="VCX65_000174"
     CDS             complement(70228..71376)
                     /gene="nagA"
                     /locus_tag="VCX65_000174"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEP5052673.1"
                     /translation="MTCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKTPRLEEFDAWQKAAK
                     GLIKKIALAPEREGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPIACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            complement(71493..73124)
                     /locus_tag="VCX65_000175"
     CDS             complement(71493..73124)
                     /locus_tag="VCX65_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEP5052674.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKLFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADGKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            73326..74048
                     /locus_tag="VCX65_000176"
     CDS             73326..74048
                     /locus_tag="VCX65_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052675.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSHP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            complement(74177..75019)
                     /locus_tag="VCX65_000177"
     CDS             complement(74177..75019)
                     /locus_tag="VCX65_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP5052676.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            75312..75869
                     /locus_tag="VCX65_000178"
     CDS             75312..75869
                     /locus_tag="VCX65_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP5052677.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            complement(75905..76729)
                     /locus_tag="VCX65_000179"
     CDS             complement(75905..76729)
                     /locus_tag="VCX65_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP5052678.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD"
     gene            complement(76731..77348)
                     /locus_tag="VCX65_000180"
     CDS             complement(76731..77348)
                     /locus_tag="VCX65_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEP5052679.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLIARGWVRAVVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            complement(77545..78522)
                     /gene="lacD"
                     /locus_tag="VCX65_000181"
     CDS             complement(77545..78522)
                     /gene="lacD"
                     /locus_tag="VCX65_000181"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEP5052680.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            complement(78569..79022)
                     /locus_tag="VCX65_000182"
                     /pseudo
     CDS             complement(78569..79022)
                     /locus_tag="VCX65_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP;
                     frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            complement(79032..79547)
                     /gene="lacB"
                     /locus_tag="VCX65_000183"
     CDS             complement(79032..79547)
                     /gene="lacB"
                     /locus_tag="VCX65_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEP5052681.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLESHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            complement(79562..79987)
                     /gene="lacA"
                     /locus_tag="VCX65_000184"
     CDS             complement(79562..79987)
                     /gene="lacA"
                     /locus_tag="VCX65_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEP5052682.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            complement(80244..81695)
                     /locus_tag="VCX65_000185"
     CDS             complement(80244..81695)
                     /locus_tag="VCX65_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEP5052683.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYADHNHLPVLVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGSQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMK"
     gene            complement(81721..82026)
                     /locus_tag="VCX65_000186"
     CDS             complement(81721..82026)
                     /locus_tag="VCX65_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP5052684.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFEMPIPTVEAGPILYRIPIMSEPVFAELERVIKENHLQ"
     gene            complement(82019..82492)
                     /locus_tag="VCX65_000187"
     CDS             complement(82019..82492)
                     /locus_tag="VCX65_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP5052685.1"
                     /translation="MFPNILFTEARTQPELFDLVASYLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            82729..83499
                     /locus_tag="VCX65_000188"
     CDS             82729..83499
                     /locus_tag="VCX65_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP5052686.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYSQFTQLLVAHENKE"
     gene            complement(83703..83906)
                     /locus_tag="VCX65_000189"
     CDS             complement(83703..83906)
                     /locus_tag="VCX65_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEP5052687.1"
                     /translation="MEKHYQVTGMTCDGCARTVTEKLSAVPGVQSVQVNLEKGQAKVT
                     GRPLTFLLKRALKDTKFELHQSS"
     gene            complement(83920..86151)
                     /locus_tag="VCX65_000190"
     CDS             complement(83920..86151)
                     /locus_tag="VCX65_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEP5052688.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKMVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPPFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGYP
                     NMDSLVALATSFAFAYSLYGVVEISLGQANFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTSQAIQKLLSLKATVVRVWRNSQWQLLPLEEVSYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGPGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIAAIADKVSGVFVPVVLVLALLTGVFWLVFMQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTITEGKPSLQKLLT
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNAALMGILGIDLSCVQSVCAKASEKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALHQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVIADLRSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRATM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            complement(86151..86588)
                     /locus_tag="VCX65_000191"
     CDS             complement(86151..86588)
                     /locus_tag="VCX65_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEP5052689.1"
                     /translation="MNQNISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKT
                     LIGRLVEKKALGTYRQGRAYIYQALLDETLLQKEALATVLDGICQRQHTHLLLERLYD
                     LPMTLEEIEAFQELLEVKKENAVLEVSCNCLPGQCHCQKKETY"
     gene            86751..87752
                     /locus_tag="VCX65_000192"
     CDS             86751..87752
                     /locus_tag="VCX65_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEP5052690.1"
                     /translation="MKKTLKSTLILLGLTLAIGASTQVDASSRSWKSWFIEKYFWLKG
                     DKGYYSEQDETKFDQYVNSAGEASNKGFDLKEEQVNGTLVTKTVDNMQVHTWNENPSN
                     KANQKVIFYLHGGSYLNNPTTYHIDMLKTLSTSLDAKIILPIYPKAPTYSYSDAMPKL
                     VDLYRDTLKETTAQNITIMGDSAGGGLALGLALALKNESLKQPKDIVLLSPWLDVTMS
                     NPDIESYESNDPILSAWGLRKVGEIWARRDPNNTKHPYVSPINGDVSGLAPITMFVGT
                     HEIFYPDVKKFDDILTAKGHQHELIVADKMNHVYPIYPIEEAKTAQYQIIDTIQKAY"
     gene            complement(87805..88155)
                     /gene="rbfA"
                     /locus_tag="VCX65_000193"
     CDS             complement(87805..88155)
                     /gene="rbfA"
                     /locus_tag="VCX65_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEP5052691.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELDKKD"
     gene            complement(88361..91222)
                     /gene="infB"
                     /locus_tag="VCX65_000194"
     CDS             complement(88361..91222)
                     /gene="infB"
                     /locus_tag="VCX65_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEP5052692.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            complement(91242..91544)
                     /locus_tag="VCX65_000195"
     CDS             complement(91242..91544)
                     /locus_tag="VCX65_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEP5052693.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAVADAGFSKKMRTLME"
     gene            complement(91537..91833)
                     /locus_tag="VCX65_000196"
     CDS             complement(91537..91833)
                     /locus_tag="VCX65_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEP5052694.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            complement(91849..93006)
                     /gene="nusA"
                     /locus_tag="VCX65_000197"
     CDS             complement(91849..93006)
                     /gene="nusA"
                     /locus_tag="VCX65_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEP5052695.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATVVEEPVVDDVMTAEEV"
     gene            complement(93181..93717)
                     /gene="rimP"
                     /locus_tag="VCX65_000198"
     CDS             complement(93181..93717)
                     /gene="rimP"
                     /locus_tag="VCX65_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEP5052696.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            complement(93825..93911)
                     /locus_tag="VCX65_000199"
     tRNA            complement(93825..93911)
                     /locus_tag="VCX65_000199"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(93875..93877),aa:Ser,seq:gga)
     gene            complement(93976..94611)
                     /gene="trmB"
                     /locus_tag="VCX65_000200"
     CDS             complement(93976..94611)
                     /gene="trmB"
                     /locus_tag="VCX65_000200"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEP5052697.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            complement(94611..95402)
                     /locus_tag="VCX65_000201"
     CDS             complement(94611..95402)
                     /locus_tag="VCX65_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEP5052698.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            complement(95466..96500)
                     /locus_tag="VCX65_000202"
     CDS             complement(95466..96500)
                     /locus_tag="VCX65_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5052699.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGYAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAILLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNVLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            complement(96503..97228)
                     /locus_tag="VCX65_000203"
     CDS             complement(96503..97228)
                     /locus_tag="VCX65_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5052700.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            97300..97719
                     /locus_tag="VCX65_000204"
     CDS             97300..97719
                     /locus_tag="VCX65_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEP5052701.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQLATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEKDGISIQYTTHEPNFPVLEKLARQINQEVSS"
     gene            97716..98072
                     /locus_tag="VCX65_000205"
     CDS             97716..98072
                     /locus_tag="VCX65_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEP5052702.1"
                     /translation="MKVKTVIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQEDSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(98183..99466)
                     /locus_tag="VCX65_000206"
     CDS             complement(98183..99466)
                     /locus_tag="VCX65_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEP5052703.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYE
                     NLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDSTASSH
                     TPTTPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(99475..99999)
                     /locus_tag="VCX65_000207"
     CDS             complement(99475..99999)
                     /locus_tag="VCX65_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP5052704.1"
                     /translation="MIQQSLVIEEGVPQDAKAVLSLVAAAAKETDFITGVETILEATP
                     HELSDFLSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQVEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            complement(99974..100435)
                     /gene="tsaE"
                     /locus_tag="VCX65_000208"
     CDS             complement(99974..100435)
                     /gene="tsaE"
                     /locus_tag="VCX65_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEP5052705.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHDSAKSRY"
     gene            complement(100589..102049)
                     /locus_tag="VCX65_000209"
     CDS             complement(100589..102049)
                     /locus_tag="VCX65_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEP5052706.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSSVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFSSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            102313..103125
                     /locus_tag="VCX65_000210"
     CDS             102313..103125
                     /locus_tag="VCX65_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEP5052707.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTHTQKIIKAVQDKGHHVIISTG
                     RPYRMALDYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTHHED
                     KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNVNKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
BASE COUNT        31207 a        21838 c        18283 g        31933 t
ORIGIN      
        1 ttcacatttt ttcctgatag catctattgc tttaccatat ttacaacagc tttattagta
       61 tacgatatct tgtataagat tgtcaatagc ttttttattt ttttataaaa ataagtgtta
      121 ggttgtactg ataaaacact aatacaaaaa aagtttaacc cttctgtgat gctttctcag
      181 tgataggctt atttggaact attttgttat aatctgatct tgcacgcacg tcacataacc
      241 tatattttaa gcaaacgtaa gtgcttaaat cttttatgga aaaacaattc agattgctgc
      301 caaagattgt gctattattt ttagttagaa aaaattctat ttttatttgg tgtcagaaag
      361 tctttgacct ttttttaaaa agtaaaaatt ctcttatgat accatgttcg tcatgagttt
      421 tttattgtta aatggaaaaa gaaaaaaacg cgctttatat tctgaaaacg cgctttttca
      481 tattttttga gaatttctag cccagaattg ggactaatct ttttttcaaa ctaattttac
      541 gtaagattta cttaaagagg aactgtaata gatacttttg ttatataatg actgtcgtat
      601 ctatcactta atctcatttt catcatgtca cctcgaaaca tgaatagctt tttcccactt
      661 ttaaaatacg tataatcatc cctgtaggtt ttagttgtga actatttagc ttctattaat
      721 cctaggtttc catcttcgcg acggtataaa atgtttgttg caccatcttc agaatcagtg
      781 tagataaaga aatcatgtcc caatagttcc atctgtaaac gcgcttcttc aacatccatt
      841 ggttttaatg tcacattttt agtacgtaca acttgtactt ctggtatctc atcgacttct
      901 tcagcttcaa actcagttgt aaagacttga ccagttggaa ccttttcgcg atgtttttta
      961 gcaattttgg ttttattttt tctaatttgg cgttcgatct tatcaacaac taaatcaata
     1021 gagccgtaca tatcctgtga aacatcttca gcacgaaggg ttactgaatc taatgggatc
     1081 gttacctcaa cttttgaaga tctctcccga taaactttta aattaacacg tgcatctatt
     1141 tcttggtctt tagcaaaata tttttcgatt ttagtaagct ttgattctac ataatcgcga
     1201 atagcttctg tcacttcgat attttctcca cgaatactga acttaatcat aggatacctc
     1261 tttctcgcgc ttgaagcgct tactttatct ttaatactat tatactgctt tcatgaaaat
     1321 ttgcaagttt taacgtgcaa ttgacaaact tttaatgtca ctatttgcta ctttagccaa
     1381 ttgttttcta agagcgataa ttgtactacc agtagtataa atatcatcta ctataaggat
     1441 tttatcagga atgtttgata cttttagtag tcgataagat ttttctacta ataatctctc
     1501 tttttttgtt ctggaagatt ggtgagtatt atctagcttt tcaaaaagag aaaggtagct
     1561 aacattagct gcctcaagaa tagcgctcac ttgattaaat tgtctttctc gaaaacaacc
     1621 gggacttaca ggaaccggga ctgggatata gcctttatag tacttggtaa taacatcggc
     1681 aagttctact gcaaaaactt ttcttaataa atagtctcct tgaaacttat attgactgaa
     1741 gtatgctttc atagcagcat tataacaata taagcttcta tgatttacat tgtatccttt
     1801 gttttcccat tttagacaat ctcgacaagc tattatatct gagtttgcac aacatgtcgc
     1861 acaaacactt tttcctatct tttgaaagct tttttgacat tgttgacaaa tcggtgaaga
     1921 gatacgcctt aaaaagatga tttctgtaat acttattggt gtttgactaa tttgttgaca
     1981 tagtagacag atcatgcgaa taccctttat aattcatttc tttaatctct tttcttgcta
     2041 gtagcattgc tttactgata ccttcatgaa agaaatataa cgttccgtct ggtctgtcta
     2101 tagatcttcc aactcgtcca gcaatttgaa caagactttg ggaactatag acacgatgat
     2161 gagacccaag aacaaaaaca tcaatttggg gaaatgtcac acccctttct aaaattgttg
     2221 ttgtaattaa aatcgttttt ttcccttgac gaaaagctgt gatatcttct ttcctgtttt
     2281 gtgattgact agaaacacaa gctatttgtt cggcgggcaa taactctttt aagattgctg
     2341 taacagattc tgccattata atagtgggta gaaaaattaa aaggggatag cctgtttttc
     2401 tttgtttttt taagtatttt aaaattttag gaggaagttt ttgccgatgt atcattttaa
     2461 atagattaaa acttcttata aatttcggaa taactaatgg cctattatta aagcgtctcg
     2521 ccaatgtcag cttgactact tctcccttgt ttacctttct ttctaaagtt ctagttgaag
     2581 ttgcagttaa taaaatcttt gcgccacctt cttttaaagc ctgacttgca gcataatgaa
     2641 gttgaatatt atttacaaaa gggaatgcgt ctacttcatc aataattaag agatcaaaag
     2701 ccttgtgaaa ttttagcagc tgatgcgttg tggctactat aataggagct ctttgataag
     2761 gaagagactc tgcgtgcatt aaacagatgc tgcaggagaa ggcttgggat aaacgagtag
     2821 ccacctctac acaaacatct actcttgggc tggcaatgca aacccagcca cctgtgttaa
     2881 ttaccgcctc aatcgcagca taaatcattt ctgtttttcc tgcaccagtt acagcatgaa
     2941 ctaatgttgt tttttgattt tgcatattga ttaataattg ttgggaaatc atctcttgat
     3001 aagcagttag ttgaccgctc caaaccagat aattaccttt tggaaaatgc ataggtggga
     3061 tagcatagag caatttatct gattgatttc gtccaaagac aagacaaaat cggcaataat
     3121 aggctccatt tggcaatcgt gcttcttcat caagctgata gtgacaacgt tgacaaatca
     3181 tttttcctct cgatattact acacttttta aaggttgagc aagctgcttt gctgaatctg
     3241 gtaactggct ttctagcaac aatcgtccat aactattttc aatagactcc atactttatt
     3301 attcgctttt ttttgctaat ttttatcttt tcttgtacaa tttttttatg gaacatttta
     3361 agacaatcaa agccagtggt tttttcgaag aaagtattaa aaaatctcgt ttcatttgtc
     3421 atatcaaacg agtaagcact gaagaagatg gtaagaattt tgttaatgct atcaaaaaag
     3481 aacattacaa agctaatcat tcctgctttg cgatgattat cggtaacaac agtcagatca
     3541 agcgctcaag tgatgatggt gaaccttcag gaactgctgg aatacctatc ctttctgtgt
     3601 tagaaaagca gtgtttaaca aatgtagtag ttgtggtaac gcgttacttt ggtggtatta
     3661 aattaggaac aggtgggcta atcagagcat actctaacat gaccgcaaca gctattaaac
     3721 gatttggcat cattgaagtt aaacagcaga taggactaga aatcacactt tcttatcccc
     3781 aataccaact atactctaac ttgctagatc aattggcttt aaccgaaaca gaaactaagt
     3841 tttcagacac gataaagaca acactttatt gtgatactga acgtgtggaa aatctcattg
     3901 atactttaac aaattattat catggtcaga taagctgtga gaaaatcgga tccaaagtta
     3961 ttgaattccc ctgtgattaa tcatcaacaa aagtgatatg gctttattat cagagtgata
     4021 gtaaatctgt attttacttt aataatatct ctccttatac ttaaatacac agcgtattta
     4081 ttttgtatca agaaaagagg ctaaactatg actaaaattt acaaaactat aacagaatta
     4141 gtaggtcaaa cacctattat caaacttaac tgtttaattc caaacgaagc tgctgacgtt
     4201 tatgtaaaat tagaagcttt taacccagga tcttctgtta aagatcgtat tgctttatcg
     4261 atgattgaag ctgctgaagc tgaaggtctg ataagtcctg gtgacgttat tatcgaacca
     4321 acaagcggta atacaggtat tggtcttgca tgggtaggtg ctgctaaagg gtatcgagtc
     4381 attattgtta tgcccgaaac tatgagcttg gaaagacgac aaatcattca ggcttatggt
     4441 gcagagcttg tcttaacacc tggagcagaa ggtatgaaag gggctattgc aaaagctgaa
     4501 actttagcaa tagaactagg tgcttggatg cctatgcaat ttaataaccc tgccaatcca
     4561 agcatccatg aaaaaacaac agctcaagaa attttggaag cttttaagga gatttcttta
     4621 gatgcattcg tatctggtgt tggtactgga ggaacacttt ctggtgtttc acatgtcttg
     4681 aaaaaagcta gccctgaaac tgttatctat gctgttgaag ctgaagaatc tgctgtctta
     4741 tctggtcaag agcctggacc acataaaatt caaggtatat cagctggatt tatcccaaac
     4801 acgttagata ccaaagccta tgaccaaatt atccgtgtta aatcgaaaga tgctttagaa
     4861 actgctcgac taacaggagc taaggaaggc ttcctggttg ggatttcttc tggagctgct
     4921 ctttacgccg ctattgaagt cgctaaacaa ttaggaaaag gcaaacatgt gttaactatt
     4981 ttaccagata atggcgaacg ctatttatcg actgaactct atgatgtgcc agtaattaag
     5041 acgaaataaa aaagggtttg gaactactaa ggttccagac tctttttagt gttctttttt
     5101 aaaaactgca ggctttcttc aatccactga ggtaactgct cttcaagtgg cctaaagcca
     5161 atcttgtgcc gactgttgga ataacgatga cgatggaaaa aatgctgttt ttcttctgct
     5221 aaggtccgca tagataaact tggcttttta ctatattcat caatatcaat tacttgtact
     5281 aaaacctggt tgcctatagc caataattga tcaatatcgt caataaatcc cgtttttatt
     5341 tctgaaatat gaatgagacc tgttgtccca ttttcaaggg caacaaaggc tccgtatggt
     5401 ttaatcccag tgatggtgcc atgcagtttg tcgccaattt tcattagtca aatacctcga
     5461 ttgtttcaat gataacgtct tctttaggtt tatcctgtgc gccagtttca acgccagcaa
     5521 tcaaatccaa aacttggaat gaagtttcgt ccacaagctg accaaagacc gtatgacgac
     5581 gatcaaggtg aggagttcca ccaattgcag cgtaagaagc tgcaattgga gccggccaac
     5641 caccacgttc tagttctttt ttggcataag gaatcttact attttgaaca ataaagaact
     5701 gactgccgtt agtatttggt cccgcattag ccatcgacaa ggccccacgg agattataga
     5761 gttcatccga aaattcatct tcaaaacttt caccatagat ggattgtcca cccattcctg
     5821 ttcctgttgg atcgccccct tgaatcataa attcaggaat aatacggtgg aagataatcc
     5881 catcatagta cccttcttta gccaaaccta agaaattggc tactgtttta ggagcatgat
     5941 ctgggaacaa gaccagggtc atatcgccat ggtttgtttt aatggttgct tttggtcctt
     6001 tatggtttgg caaatccaat tgtggaaact gtaattcttt gtcaatcaat cctaattcct
     6061 ccaaggcata taaaatgcca tcttctttaa ctttttttgt gataaaatct gctttttctt
     6121 gcagtaatgg atgtgatact cccattgcaa tactgatacc agcatagtca aataactcta
     6181 ggtcattgag ttcatctcca aaaaccaaaa tgttttcagg ttttaatcct aaatggtcaa
     6241 ctacttttga aacacctagc gcttttgacg tacctttcaa gacaacatct gatgagttat
     6301 cgtgccatct gaccaaacga aggtgctctg ctaattcagc aggcaactgc aagccatctc
     6361 ccttgtcctc gaaagtccac atctggtaaa catcatgata ctcattataa tccggacaga
     6421 cctctagttg agcgtagaca ttatcaatag cattgctaat catgtcattt cgagcggaca
     6481 acaccgcttc atgacgaccc gccattccat aaaaaatgcc catatcatcc gcccattttt
     6541 tataggccac aacaacatct gctggaatcg gagcttggaa aataatagtt ttagcatcgt
     6601 ctttgacata agctccattt aatttgacac aatagtcagc atgtaaatct tgaacttctt
     6661 gtggaacacc gtaccgagcg cgacctgaag caataccaac caagatgcct tttgccttca
     6721 aagccttaaa tactctttga atcgactcag gcatataacc cgtatctttg accctcaagg
     6781 tatcatcaat atcaaagaac accattttga tttttttagc tttgtatttt agttttgcgt
     6841 ccatactttc ctccaatttg ctatacccta tattatagca ttaattatcg tcttggggga
     6901 ctaaatgatg tcgaaaagca tagacaaccg cttgggttcg gtcatcaact tctaacttgg
     6961 ctagaatatt ggacacatgt gttttgacgg tttttaagga aataaagagt tcatcagcga
     7021 tggtctgatt atcataccct ttagctaaaa ggtgtaaaat atcatactca cgcgctgtta
     7081 gttcctcatg caagtcaggg tgttgatcat gcgccttaat ttttttgtca acttctgttt
     7141 caatagctaa ctctcccttt gaaaccttgc gaatggcatt taaaatttca gccgcactcg
     7201 atgtttttaa catataaccc ttcgctcctg catcaatgac agggtatatc ttttcattat
     7261 ctagatagga agttaacaca agtaccttag cctctttcca tttttttaga acttctaaag
     7321 ttgcctcaac accgcctaac tctggcatca ctagatccat aaccaaaaca tctggcttca
     7381 aagccaatgc caaatcaacc ccttcacgtc cattagaggc ctcaccaacg acatcaatat
     7441 cagcttgtaa attcaaaaaa ctcttgagtc ccatgcggac catttcatga tcatcgacca
     7501 atatcacttt tatcttactc atcgtcatct cccttcacta tcggcagtct aatatccatg
     7561 gaaactcctt tgcctttttg actaattaaa tgtaggtttc ctgctaaatc attgacacgg
     7621 tcttcaatat tcttcagacc ataactcaaa tcccttacct gatccatatc aaatcctaca
     7681 ccatcatcaa tcatcttcaa ttgtaattct gttgaggttt gattgagata aacttcaatt
     7741 cgactagctt tagcatgttt taacgtgttg ctaatgaatt cttgggcaat tctaaaaaga
     7801 ttatcttcca ttgttttagg aagctgagca atggtttcct tataaatgac ttcaatatca
     7861 cttttatctg ttaattcctt aagaatcata tgaaggccct cagataaagt ccgattagct
     7921 agctcggtag gtctaagatg caaaaggaga atgcgtagat cattttgagc attttgcaac
     7981 attgcttcaa ccgttgttaa ctgtgtttgt aattgtgttt tgtccagttg ttccaaactc
     8041 attgaaattc ctgataaaat caatgacgaa gcgaatagct cttgactgac tgtgtcatgt
     8101 aaatctcttg caattcgttt gcgctcttgt tttacaactt cttggctatc aagaatataa
     8161 gcactttctt tcttttgcat gttagcagtc aggtgagaca tttttttaga aagtcgactt
     8221 aaattagtat tgatttctga tgtctcatct agatagagtc gtcgattatt gagaatatat
     8281 tttagatttt ggttgatgtt acgcttactg ttatcatcca taataatcca caataacaac
     8341 aataataaag tcacagaaac aatcaacaat aaaatcgaaa accctagacg ttcgacctgc
     8401 cataaatgat tgcgaaggta gttaaaagtg attcctaaat tatccatgac cacaaaaaca
     8461 atagataaaa tggtaatggt tgagtagagc caaacaagag catagtaacg ttttttcatc
     8521 gcctatccac ctcaacattt ccggcaatag ttgtaacgat aattttgact tttttaaggg
     8581 attggttatc cgtttctttt aacttaatag attcgttgcg caaatcatat tgctgacatc
     8641 taaaaaaatc aacacttccg tatatggaac taacatctaa agtaacagtg acatcaatag
     8701 gtaccaatat agtcgtattt ccaaaaattt tacgtatcac aatgatatta tccattcctg
     8761 tcacaataac attggttaag tcaaccgtgt catttcctga gattcgaatg atgttaatgt
     8821 catcaaaaca ataataatca ctttcataat tagcagtacc aatccattga tgcttggtat
     8881 tgttcacttc aatcttttct tccttgaaac gaatcaaggc aaagcgattc ttctttttga
     8941 cttgtgaaaa atggttaatg aaaatgtaaa ctatccccaa aagaacagcc atgataatgt
     9001 agggattaag catgaaaatt aaaaaaagaa acaataaact gacagttagt aaaaaattat
     9061 tgcggctatc ttggttataa aagcgtaatg ctaataagat aagaactaga attaggataa
     9121 aacttgataa atcattatcc aagattgtca tgatacccat agctagcagt atacactcga
     9181 taagtaaaaa gaattgaaat tttttcatta gtttcccctt atttctttgt attttatcag
     9241 aattcctgga aaattgcatc tttatatgac gagtagttaa aaagaatagt tagtggcatg
     9301 ctagtaaaac atgagactaa ctattctttg ttaaggtgtt tgagcagtag tttctgatgg
     9361 gcttaattca gtgttgctac ctggtgcagt actatcattt gttgaagaac tgtttgaact
     9421 tgacgttgaa ctcgatgagc tactagaaga gtgtgtttct tctggataaa ggtaaagact
     9481 aatctctcct ttatcagaca gactcaaaga cgttccatag taaggagatt gaccactgac
     9541 aatagcttta gaactaggag aatgaattgg cacaaagccc gttgctgagc tagagcttgg
     9601 cacataagct tttattctag atgcatctat acctaaagct gttaaggtat tgactgcatc
     9661 tgcataacta tattctgtta ccataggcat agtgatcgta tcactaacag caacactgag
     9721 cgtaatttta gactttccgt ttggattaaa tttatcaccc gcacttggcg attgactgat
     9781 gactgtattt tcaggatatt cattagttac aatgcgctca attttgattt ttgattttgg
     9841 aacaccataa gtttctatca aactattcat agcttcttga taatctagtc ctttgtagtt
     9901 ttccatgtca aaacctttgt ttccaattga cacataaagc gtaatgcttg agccttgcct
     9961 cttagctgtt cctgctttag gatctgttct aactacattt ccctcagcaa ccgtatcact
    10021 ctcaatttgc ctgattttac ccacttttag cccaacatca tacagttctt gtttggcaac
    10081 tttaagacta gtgcctgcta cattaggaac tttcacagaa gttggtttag ttagtataag
    10141 ataagtaaag agtgctacac ctacaataaa gaaagaaaaa agaattttga ataaagtacc
    10201 taaaaaacga ccactttttt tctttttggt ggggggctgt aaagcatctg tttgattagt
    10261 ttgatccaat cgactttcct gtgttaacac tgttggggta gggggagaca attttacaga
    10321 agcggtggga cctgaggcca ctttggggag gggtttggta ctttcaacat cctcaaagac
    10381 aatcttacgc tcccgactac gattataact aagcgccgtc attaagtcac gactcatttc
    10441 aaaggttgac ccgtaacgat cacttaattt cttggctgtt gctcgaataa caacattctc
    10501 caaagcttgt ggcacattgt ggttctcctc gataatagat ggaagaggct tttgaaaatg
    10561 ttgcaaggca atcgtaacag cactatcgcc atcataaggg atatggcctg tcaacatctc
    10621 aaagagcata atccccatcg cataaatatc actttgaatc gtcgctttgg agccgcgagc
    10681 ctgttctgga gacaagtaat gaacactgcc taacatcgaa ttagtttgtg tcaagcttgt
    10741 ttctgcaaag gctactgcga tgccgaaatc agttactttg acaacaccct ccttagttag
    10801 taggatattt tgaggtttta aatctctgtg tacaattcct ttttggtggg ctaaagtcat
    10861 agcagaaagg acttcttcca taattctaac cacttcatta ttagataatg gagcatgatt
    10921 ttgaatgtat ctctttaggt cagcaccatc cacatattcc attactaaaa attgctgtcc
    10981 gtcttcttca cctatatccc ggatggcaac aatattggga tggttcaatt cagccatggc
    11041 ccgcgcttct cgttggaaac gcgcaactgc tacctgatct gtttgataat tggtacgcaa
    11101 gaccttgatt gcaacgtctt cattatccaa gatcaaatca tttgctaaat aaacatccgc
    11161 cataccaccg cggccaatag atttcagaat gcgataacga ccagcaaata atttgccaat
    11221 ctgaatcatt cgacgtcctc actttcgttg tgaaccaaag cgattgtaat attatctagg
    11281 cctcctctta ggttagctaa gtcaatcatt tcttggtttt tttcatcaag actaacctta
    11341 ctgcccaaga tagtcacaat ttcatcattt gaaatcatat tggttagacc atcactgtta
    11401 atgacaagat aatcccctgg ctccaaaacc ctcactccta aatcaggctc tactggggaa
    11461 gcttgaccaa tagattgagt gataatattt ctttgtggat ggctagcagc ttcttcttct
    11521 gtgatctgtc ctgccttaac caactcattc actaaagaat gatcactggt caataaggta
    11581 taatgcccat catggacaag accaatccgt gaatcaccaa tatgagcata aatggcgcta
    11641 gattcaacta aagctactgc ttcaacagtc gttcccattc ctttaaagtc ttctgattgg
    11701 cctagatcat aaatccgttg attttctgac tggatagttt caaataacca atctctaatc
    11761 tgacttaact ctgtgaagtc tgtttttacc cattctcttc ccaggtctgt gactgtcatc
    11821 tcactggcaa tatttccagc tctgtggcca cccataccgt ctgctaaaat cactaaagtg
    11881 atgccttttt tattatcaaa cttattgata aaatcttgat tgtttgagcg tttttgccca
    11941 atgtctgttt ttaatgaaat cttcatacgt tttttctgac tcagtcagtt tcctcctaaa
    12001 atactacaag actcgtctga cttgtccaat aaagaagcca tcagtctggt attgttctgg
    12061 tgtgataata agataaccat ccttgacaat atctgcttgt gtatggttca gttttacttg
    12121 ttcaaaatta ggatgacttt gtaaaaatgc ttcgatgact tgacgattct cctcatcaaa
    12181 aatagtgcaa gtactgtatg ttattatacc acctttacgc aaggtttgac aaacactaga
    12241 caatatctct agctggatag cctgtagagc attgaaatct tgactttctt tattatattt
    12301 gatatcgggt tttcgacgaa tcaaaccaat tcctgagcaa ggagcatcca ccaaaatctt
    12361 atcaaagcta tccttttcaa aatgacgatg aacctctctg gcatctagtt ttcttgtctc
    12421 aatgttatca gcaactccta agcggttagc attttccttc accaactcta gtttatgatc
    12481 atagagatct aaggcaataa ctttacctgt ttttaagtaa gatgctatat gagaggtctt
    12541 gccccctgga gcgctacatg catcaagaat tatgtcgtca ccgtcaatgt ttaaagtagg
    12601 agctacaagc tgactgcttt catcttgaat agtgatgtcc ccatttgtga aataatcact
    12661 ggctgcaaaa tgacctgacg ctttggttaa accagttgct gataaaaggg aacgttctgc
    12721 atctaaagcc tcagcagctt cctctagctt caaagggtct gtcacgcgaa tactagcctt
    12781 actacgcaca aataaacttt ccatgatggc cactgatctg tcagaaccaa attggtcttc
    12841 taacttttta accaaccaaa caggcagtga atacttgacc gaataatact tatttcgacg
    12901 cttaattgtt tccatatctg ggagaggatg gctggtgaat tgacgtaaaa tagcattgac
    12961 aaacttctct gcaccttttt tattgccacg atttttggca ataccaaccg catcgttaac
    13021 aatggcatgc gctggtaact tatctaaata aatcagttga taaagactga gcataaggag
    13081 ataataaacc catttgtcca atttatctcg gtctttgaca taatgggcta aataccattc
    13141 caagctaatt ttacgtgaaa cggtaccata tacaatctca gttaatagag ctctgtcctt
    13201 agcagataaa gctttattgc ttagctgctg attaagcgct atgtttgtgt aagccccctg
    13261 atcaaaaata tgttctaagg ttagaagtgc ttttcctcga atacttattt tccaattatc
    13321 tgccaatgaa atcacccact tcaagttttc taccaaggcc atttaagaaa tctgcaatag
    13381 ccattttagg tttccccgca ggttgcacaa ccagcaatga cagggctcct tgaccagcag
    13441 ctattaccaa agattttttg gttttgacaa taacttgtcc aggtaatcct tctccttcag
    13501 ctaattgagc ttcgtaaatt tttaaacgtt gcccctctaa aaacgtatgc gctaccggcc
    13561 aagggttcat acctcgaata tgattgaaca cttcttgatc agacattgtc caatctaatt
    13621 tttcttgttc tggagagata ttaggggaaa aagtagcttg gctgtgatct tgaggaatag
    13681 gttttaattc tccagaaaga taagctggca aactatccaa aagtaagtct cgaccaatga
    13741 tggctaattt ctcaaaaaga gtacctacat tatcggtttc aagaattgga gtgcttgctt
    13801 tagcgaccat gtcacctgca tccatttctt ttatcatttc cataatagta acgccagcct
    13861 ctttatctcc attcataata gcataatgga taggtgctcc acctcgatat ttaggtaaca
    13921 atgatgcatg tacattaata gcaaatgaaa ctgaatcaag taatattgtt ggtaaaaatt
    13981 ggccaaatgc tgctgtaata ataccatctg caccaagttc cataatctca atgagttctt
    14041 gagagcctga taatttttcc ggctgataga ttgatattcc atgctcaaga gctaattgct
    14101 ttacaggtgt taccttaata tcttttttgc gtccaacagc tcgatcaggc tgagtaacca
    14161 ctcctaaaat ctcataggca ggattatcta gcaagccctt caatacagtt gctgaaaatt
    14221 ggggagttcc cataaataat aattttatca tgactttcct ctttgtattt ttattatatc
    14281 ataactgatc atcctagatt tagtgattta ccttataaaa attgttgcgg ttcacaatca
    14341 ataattagtt ttaaatgacg attatctgct tcttgactcc aatcaagaat acgattgagc
    14401 gtctcttcta ggttatcttc aaaacggtat tttaacaaaa tttgatagtg gtataaattg
    14461 tgtgttctag caattggctt aggagtcggt cctaatattt taatattatc cgataagtga
    14521 ctctttagca gttctgtaac ttgataagct ttttttacaa ccgatgcttc taaacgatgc
    14581 gaaagcgtaa tacccactgt aaagtagtaa gggggataag ccatctgacg gcgaatcgcc
    14641 atttcataac ggtaaaaggc ttcaaaatct tgttgtttag ctaattgaat agcatagtga
    14701 tcgggattat aagtttgaat caagacttcc cctggcttat gggcacggcc tgcccgacca
    14761 gcaacctgtg ttaacaattg aaacgttttt tctgacgctc gaaaatctgg caaatttaag
    14821 gaggtatctg catttagtac cccaactaaa gtcacatttg gaaaatccag tcctttggca
    14881 atcatttgcg tccctaacaa aatatctgct tcctggcgac caaaactatc tagtatggtt
    14941 ttgtgacttc ttttttttcg tgtggtgtca acatccattc tcaagatcct agcttctggg
    15001 ataacccctt gcaattcatc aaaagctttt tgagttccag tgccataata gcggatactg
    15061 ttgctatgac actcaggaca agtaattggg ataggttttt gaaacccaca gtaatggcaa
    15121 ttcatagttt tagtatccat gtgaagggtt aaagagatat cacagttggg acatttgtcc
    15181 acataaccac agtcccgaca catcacaaaa ctagaataac cacgtctatt taacattaag
    15241 acaacttgtt cttttttaac caaacgttct ttaatcttat caatcaaata tggggtaaaa
    15301 ttactaactg cttgctgtcc aatataatca cgaaaatcaa caatcgttac ttctggaatc
    15361 ttagcaagag ggtttgctct tttcgttaat tgaataaaat gatagacacc cttactagcc
    15421 cttgctcggc tttcaatact tggcgtagca gagcccataa ccacaactgc ttgatggtgt
    15481 ttagctctga gcagggcaac ctctctggca tggtatctag ggttgctttc ttgtttatag
    15541 gttgattcat gctcctcatc aataataatt gcaccaatcc gctctagtgg agagaaaata
    15601 gcagagcggg caccaaccac aaccttagcc tgtcctgttt ttatcttgcg ccactcatca
    15661 aacttttcac catctgataa gcctgaatgc ataatagcca cttgctttcc gaaacgggaa
    15721 ataaaacgag aggtcatctg aggagtcaac gaaatttctg gtactaaaac aatggctgtc
    15781 ttatcctgtt ttaaaaccgc ttcgatgata tgaagataaa cttctgtctt acccgaacct
    15841 gtaatacctt caatcaaaaa aggtttactc ggtttcccaa tttgctcaac aatttcagta
    15901 acagctgatg cctgctgttc atttaaggtt aaaaaagaag atggtttgat ctggtcaaaa
    15961 tagggctcac tgcgatcaat ttgacgttcg tcaatacgaa ttaagtgatt tgtcacaaag
    16021 taagccacca catctctaga aaaggcttga taaagcgttg caagtttagc ttccttcgta
    16081 tgggttagca gatagtcttt taataattga cgctttttgg cacgactaga gatgggatgt
    16141 accgctaagg cgtctaagtc gacgtgataa tatttttctg tctttaggtt tttcttgtct
    16201 ttggctaaat aactaacagt aatatgccca gcttgtatgc ccttaagagc tattttttcc
    16261 ttctcgcggt ctaaggtaga atataagaca gatggttttc cttcaaaaag aaagtcccta
    16321 tcaggctttt ttagacctga ctctggcctt agcactttat catagttaga gttaagaaga
    16381 ttaggaatca ttgcttttaa gagcgtgatt ttataagaaa aaactgtttt tcgaagctga
    16441 tcagcaaggg tcaattgttc ttggtttagg actggctcag gatctaaaac ggtctgaatc
    16501 agtttaagag agcttgaatc ttcctggcca aaaccaataa caaagccttg caacaaacga
    16561 ttcccttttc caaaaggaac atgcacacga gaaccaagct gcacgagaga aactaactct
    16621 tttggaatac cataagaaaa tggcttgtcc gtttgcatca atggaatatc tacaatcaca
    16681 tgagctactt tttccatttg cttctccttt tctgtcatgg acatcgtact aaatatgaaa
    16741 aaatctaaga tttctgaaac cttagatttt ttctccttct tcttcttttt ctttggcaat
    16801 ttgttctttg attttacgtt cctcttcctc tttggccaag cgttctgcct caatcttagc
    16861 acggacagct tcacgtttag ctgaaggatc tgggtgaatc acaacgtttc ctgattcaat
    16921 ttcttcaagt gcctgaagtg ttgacttcac tgatttaaat tcttgagttg gagtggcacc
    16981 agcttctagt tcatgggcac gtttggcttg taaaatcaca agtgaatact tagatggtac
    17041 tttatctaat aaggtatcaa tggaaggttt taacatcata atgcttactc ttttctattt
    17101 agctttaaag ggattttttg ttattttaat cattttatca taacgaccaa tcacgcgctc
    17161 cacacgaaag tgttctgtct caatgatacg cttaacccgc tcagctgcca aggcaacttc
    17221 atcattaaca actgcataat cgtattcgcg cataagggca atttcttctt ttgctctttc
    17281 aatacgttga gctatgactt cttgactatc tgtaccacga ccaaccaggc ggtcttctaa
    17341 ttcatctaaa tctggtggtg ttaaaaaaac aaaaacacca tctggtactt ttgacttaac
    17401 ctgaagagct ccttgaactt caatttctaa aaagacatca attcccttat caagagtctc
    17461 attaacataa gttaaagggg tgccatagta attaccaaca tattcagcat actctagcat
    17521 ttgaccagtt ttaatgagtt cttcaaattc ttcacgtgtg cggaagaaat aatcaacccc
    17581 atcaacctcg cccggtcttt gcggacgagt cgtcattgaa accgaatatt caaatttatg
    17641 atctggcgtt gaaaaaattt cttgtcttac cgttcctttt ccgacacctg aagggccaga
    17701 aaagacgatt aacaaaccgc gttcagacat tatattctcc ttattagttg ctttttaata
    17761 gtttatcaaa aaggctagtc tttttcaaga acattttcaa aggcaagtca taaagaaaaa
    17821 gaggataatt cctctttttc tacttggcat aatcaaccgc tctcatctca cgaataacag
    17881 ttactttaat atttcctggg taatctagat tgttttcaat tttttctctt actttatgcg
    17941 acaaaatgac aacctgatca tctgaaattt tttcaggttg aaccataata cgaatctcac
    18001 gtccagcttg tagagcaaaa ctattttgta ccccatcaaa acttgtcgcg atttcttcta
    18061 aatcacgaag acgcttgatg taattctcca ttgactcatt acgagcgcct gggcgagccg
    18121 aactgagagc gtctgctgca gctactagca cagcgatcac agaatctggc tccacatctc
    18181 cgtggtggct agcaatagtg ttgacaacaa ctggatgttc tttgtattta cgtgcaaatt
    18241 ccattccaat ctcaacgtga ctaccttcaa cctcacggtc aatagcttta cccatatcat
    18301 gcaagaaacc agcgcggcgg gcaagggcaa cattttcacc cagttcacca gctaaaatac
    18361 cagctaactt accaacctca acagagtgac gtaggacatt ttgaccaaac gaggtacgga
    18421 attgcaggcg tcccatgatt ttaatcaaat caggatgaag gtttggtgca ccaatctcat
    18481 aggctgcagc ttcaccgtac tcacgaatac gattatccat ttcaagacga tttttctcaa
    18541 ccaattcctc gatacgagct ggatggatgc gaccatcagc aatcagagat tccaaggtca
    18601 tacgagcaat ttcacgtcga ataggatcaa atcctgataa gataacaact tcaggagtat
    18661 cgtcaataat aacgtcaatg ccagtcaagc tctctaaagt acgaatatta cggccttcac
    18721 gtccaataat tcggcccttc atgttgtcgt ctgggagatg gacactggta atagtttgtt
    18781 cagtcacata ctcaccagca aggcgttgca tggcttgcgc taacaagtcc ttggctgttt
    18841 taactgttcg gtccttgatg tcacgttcgg catctcgaat gcgcgtcgca atttcatggg
    18901 tcagtttgtt ttccgtctcc attaaaatca cttcacgcgc ttctgcaatc gtcatcgcag
    18961 caactttttc cagttctgct tttttctcct cttcaagttt ttccacttga agttgccgct
    19021 catcaatgtg tttagattta tcggtcagac tttgttcttt actatctagt accttttctt
    19081 tacttgatag gttttcatct ttacggtcaa gagttaagga gcgctccgct aagcgtgtct
    19141 cgagttgttt aagctcttgt ctttcagact taaattcttg ttcaatctct tcacgatatt
    19201 ttcttgcctc ttcttttgct tctaaaagta attctttacg atttgcttta ctttcacgtt
    19261 tagctgtttt tttgatgtgt tcagcatcta cttctgcttt gccacgaata tcaacagctt
    19321 cttgttcagc gtttaaaaga gtcaactctg cagcttcctt cgcagacttg agtctaatcg
    19381 aaataagtgc ataacctaat attaaaccaa tgagggcaga aacaattaat aaaataatat
    19441 taaccatgtt tgtacctcaa tatattctag atttcattaa tagaaagcca tctcttagtt
    19501 tatcataaat tgagcgttta cacaattcca attcattttt aaaaaaatta acatttgggc
    19561 caagtagttg agaaccctac ttaaaaaaag actgtagcaa gtcgtccatg atgtaggctt
    19621 ctatttcaga ataacttttt ttccggaggc gtgttaagac aacacgccaa gaaatgggac
    19681 gttccattag aatacactta atgtccttga attggtataa ttctgtaata ggtttgggac
    19741 aaatagttaa gacgttgtga ttaatcttgg tagaattaag cataaaatcc caggaagagg
    19801 acgtcaaaat aatattaggt ctgacttggt gacgctcgca agcttcaagc actaaatggt
    19861 gaaccatgaa actaggatca aatagggcaa gttgttcatc tgttaaatct tcccactgaa
    19921 taactttttt ggaagctaaa cgatggcgtg gagacaggca tacagataat tctgatctct
    19981 ggatttcata agtctcaacc aaattatcag cgatgcctgt tggggataac aagactgcga
    20041 cgtcaacatt tcccacgagt agttcatttt ttagttggta agcaccaatc tccttaacat
    20101 tgaattgaat ccccggattt tctaaaatca gttttggcat tacttctgag aaaacaactg
    20161 ataaaataag aggaggaata ccaatactga tacttccctt taacccttta ctgtgatcat
    20221 gcaatttcaa aaacatgtca tcatagagac tgagaacctt ttgagcgtcc ttataataat
    20281 tatcaccaag ataggttaac ccaataatac gacctctttt tcgtttgaag agcttaacat
    20341 tttctctttt ttcaaaatcg ttaatcatca tactcagcgt cggttgagaa acatacaaca
    20401 gttccgccgc ctggctcaag ttaaaatgat tttcaacgat tgcgataaaa taacgaattt
    20461 gtttaatatc caaataggat tctccttgtc ttatcaatta ctttttccgg tataattacc
    20521 tatattatga cacaagtaga tgttaaatgc tattgccaac tctatcaaaa aaaattatat
    20581 gcttataaaa attctatatt tttattttta gcgttttctt gttatcttag agacatggaa
    20641 agcgctttct aaaactgaaa ggatgtttat tttatgaaaa acatagttat cgttgaagct
    20701 ttacgaactc ctatcggagc ttttggaggc tcctttaaaa gtgtctctgc tgttgaactt
    20761 ggaacaactg tactgaaaaa aatccttgat aaaacgcaag taaagcctga aatggttgat
    20821 gaagtcatcc taggaaacgt ccttcatgca ggcctaggac aaaatgtggc aagacaagtt
    20881 gcagtccact caggaattcc tgaagataaa acagctttca cattagatat ggtttgcggt
    20941 tctggactta aagcaatcca attagctgcg caaagcatca tgcttggtga cgctgatatc
    21001 gttattgctg gtggtgtcga aaacatgtca caagcagctt atgtctcaac tcagcaccgc
    21061 tttggtcaac gtcttggtaa tagtcaattg attgatactc ttgttcatga tggcttaaca
    21121 gatgctttta acaattacca catgggtatt actgctgaaa acgttgctca gaaatatggc
    21181 atctcaagag aagagcaaga tcaatttgct ttagaaagcc aagaaaaagc tgctaaagca
    21241 ttagaaaatc atcgttttgc tgacgaaatt gtccctgtct ctgtgcctca acgacgcaaa
    21301 gaccctttaa ttgttacaac agatgaatac ccaaaagttg atacaagcct tgaaaaatta
    21361 cagcaattac gtcctgcttt cctccctaaa gaaggaaccg ttactgctgg gaatgcctca
    21421 ggaataaacg atggtgcagc cttattgatg ttaatgactg aagaaaaagc tcttgaatta
    21481 gggttaacac ctttagtcac tattgaaagc tatgctagtg caggtgttgc acctgaactg
    21541 atgggaactg gaccaattcc tgccactcaa aaagccctta agaaagctgg attaacaatt
    21601 tctgatttgg acttagtgga gtccaatgaa gcatttgcag cacagtcctt ggcggtttta
    21661 aaagatttaa agttaaaccc agaaatcgtg aatgttaatg gaggagccat cgctttaggt
    21721 catcctattg gtgccagtgg cgctcgcatt ctagtcacat taatccacga aatgaaaaaa
    21781 cgccaagtaa ccagaggact agcaacactt tgcattggtg gaggacaagg aactgctgtt
    21841 atcgtgaaaa acaatactta gtctcgtgaa agttggtaga aaaaatgtgt aaagaaatca
    21901 caataaaaga agcggtagct cacgttaaag atggtgatac cattatggtt ggtggcttca
    21961 tgacaaatgg cacaccagaa aaattaattg atacacttgt ggaaaaaggt gtcaaagacc
    22021 tcactttaat ctgtaacgat gccggttttc ctgacaaagg cgttggtaag atggttgcca
    22081 ataaacagtt ttcaactatt attgcatcac atatcggtct caaccgtgaa gcgggccgac
    22141 aaatgactga gggcgagact gtaattgatc ttgtacctca gggaacatta gctgagcgca
    22201 tccgcagtgg cggttttggg ctaggcggtt tcttaacacc tactggaata ggaaccgaag
    22261 ttgccaaagg aaaagaagtc attactgttg acggcaaaga ctaccttctt gaaaaacctt
    22321 tgaaagctga tatcgcactt atttttgcta acaaggcaga taaaaatggc aatttgcaat
    22381 acgcaggttc tgaaaataac tttaatcatg tgatggctgc taatgcgaaa accaccattg
    22441 ttgaagcaag agaaattgtt gacgtggggc aaatggatcc taattttgtc catactcctg
    22501 gcatttttgt taactactta gtgaaaggag cctaacatgg gaacatcagc tactgttctt
    22561 tcaaaagaag agattcaaac acgtattgct aagcgcgttg cacaagaatt agaacacaat
    22621 acactggtca acttaggcat aggtttgcca acaaaagtag ccaactatat tcctgaaggt
    22681 gtaaccatta ccctgcagtc cgaaaatggt tttgtcggtc tcactggatt aacagatgat
    22741 cactacgatc ctagtattgt taatgctggt gggcaacctg ttagtattgc tcctggaggg
    22801 gctttcttcg atagctcaac ttcctttggt attattcgag gcggccatgt ggccgcaacc
    22861 gtcttaggtg ccttacaagt tgataaagaa gctagcattg ctaattacct gattcctgga
    22921 aaaatggttc ctgggatggg aggggccatg gacttattgg taggtgctaa aaaagtcatt
    22981 gttgcaatgg agcataccaa taaaggcaaa gcaaaaattt tagacaaatg cacccttcct
    23041 ctcactgctc aaaatgttgt taacctaatc attactgaaa tgggagtctt tgaatatcaa
    23101 gatgaaggtc tatgcgccct tgaaattaac ccagattaca cctttgaaga cgtgcaaaac
    23161 gttaccgaag ttaccctaat tgataaaaca aactaaagac taaccaaaag aaagacgagg
    23221 atagtatcat gacacatact aaagaagttg catttatcac tggtgctgca agcgggattg
    23281 gaaaacaaat cggggaaacc ttcttaaaag aaggtaaaac ggttgttttt tctgacatta
    23341 atcaagaaaa actggatcag gttgttgctg actatactaa agaaggctat gacgctttta
    23401 gtgttgtgtg cgatgtcacc aaagaagaag ccatcaatgc tgctattgat acggttgttg
    23461 aaaaatatgg tcgtattgat attttggtta acaacgcagg ccttcaacat gttgccatga
    23521 ttgaagattt tccaactgaa aaatttgaat tcatgattaa aatcatgttg acagcaccat
    23581 ttattgccat taaacgtgct tttcctacaa tgaaagctca aaaacacggt cgtattatta
    23641 atatggcttc tatcaatggt gtcattggtt ttgctggcaa atccgcctac aattcagcta
    23701 agcacggctt gatcggtctg accaaagtaa ctgccttaga agctgctgat tcaggcatta
    23761 cggtcaatgc catttgtcct ggatatgttg acacaccact ggttcgtggc cagtttgaag
    23821 acctttccaa aacaagaggt attccccttg aaaatgttct tgaagaagtg ctatacccac
    23881 ttgttcctca aaaacgcctc attgacgttc aagaaattgc agactatgtg tctttccttg
    23941 ccagtgataa ggcaaaaggt gttacaggtc aagcctgtat cttagacggt ggctacactg
    24001 ctcaataaat ttggagagat aaagaggctg tatcttgtga tctgtctctt tattttctaa
    24061 taaggaggtc ataaaactat ggaaattatt ggttctctgg gggtcttgat aggtgttatt
    24121 gttattattt acctgtctgt caaagaagtt aacattatca tcgctgcgcc tcttgctacc
    24181 agcttggtca ttttgtttaa tcaaatggat ccaaccacaa ccttacttgg aaaagaaccc
    24241 aaccaattta tgggggcact ctccacttat attctcaatt attttgctat ctttttatta
    24301 ggttctatct tagccaaatt aatggaaaca agcggtgaaa ccacttctat tgcagattat
    24361 attttaaaaa aagttggtca tgatagtcct tataaagtac tcgttgctat ttttctaatc
    24421 agtgctatat taacttacgg gggaatcagc ctctttgttg tcatgtttgc tgtcttgccg
    24481 cttgcacgaa gtctattcaa aaaaatggac ttggcttgga acttaattca agttcctctt
    24541 tggctcggta ttgcaacttt taccatgacg attttacccg gaacacctgc cattcaaaat
    24601 gttattccta ttcaatactt ggacacctca ctaactgctg ccgccattcc gagtatcgtt
    24661 ggctcaattg gctgcgtgac ttttgggctc ttttatatga aatattgtct agcaaaaagt
    24721 atggcaaggg gtgaaactta tgccacttat gcttttgaca atgagataca agtgaaaaca
    24781 aaaaatctcc cacatttcct tgccagtatc ttacctttat tgttgctcat tattatcgcc
    24841 ctaaccggta gccttttcgg aaacgatttt tttaagaaga acattatttt catagcactt
    24901 ttagctgcca ttctcaccgc aagctggctc tttagacagt ttattcctaa taagattgct
    24961 gtctttaatt taggagctag cagctctatt gcacctattt ttgcgacagc atctgcagtt
    25021 gccttcggag ccgttgtgat gattgcccca ggtttcacat tcttctcaga tctcattttg
    25081 aatattcccg gtaatcctct tattagttta gccgtgttga cttcctctat gtcagctatt
    25141 accggctctt cttccggtgc tctaggaatt gtcatgccta actttgccca gtattattta
    25201 gatcaaggcc ttaatcccga aatgattcac cgtgttgcca ctattgcttc taatatcttt
    25261 accattgtgc cccaaagtgg tgtctttctc accttcttag cattgacagg acttaaccac
    25321 aaaaatgctt ttaaagaaac ctttattact gtttctgtaa gtacttttat cgcacaggtc
    25381 attatgatag cctttgatct gttttcttag ccttttctcc tccacaagta gccactttct
    25441 cactatttgt gttatgataa agtgtaaaac aaaggagatt gaaatgacaa aagaagttat
    25501 cgtcgaaagt tttgagctag atcatactat tgtaaaggcc ccttatgttc gtcttatttc
    25561 tgaagaattt ggacccaagg gcgatcgtat tacaaatttt gatgttcgcc tagtgcagcc
    25621 taaccaaaat tctattgaaa cagccggttt gcataccatt gaacacttac ttgccaagct
    25681 catccgccaa cgcattgatg ggatgattga ttgctctcct tttggctgtc gaacaggttt
    25741 tcaccttatc atgtggggaa aacacagttc tactgatatt gccaaggtga ttaaatccag
    25801 cctagaagaa attgcaactg ggattacttg ggaagatgtt cctggaacaa ctcttgaatc
    25861 ctgtggaaac tataaggatc atagcctctt tgccgccaaa gaatgggctc aattgattat
    25921 tgatcaaggg atttcagacg atccttttag tcgccatgtc atctgatact agtgtgttgt
    25981 caaacataac aatcctactg acctatttga cttgttacaa aaaacaagtc tatctgcaga
    26041 ttttaagaca acatacttta ttaatcaaaa aactgagaca agttgcctta tctcagtttt
    26101 ttttgatttt ctcagtaatc taaagcatca gcataacctt tgccatttcc tacaaaataa
    26161 cccgtcttac aattaataga gaacagataa gtgccatcag gcttaaacat attatagtaa
    26221 ccattgccat taataatatt aaccggctct aaaatatatt ggtagcctga aatataacct
    26281 ctagcttgtg aggttgctac aattttttca agaactcctg gattaaatgc ccaagatggg
    26341 ttagctctgt cagcaataac atcttgattg taaggtacac gtgataaatg ccgttgtaag
    26401 cttgcagggt cataacttgt caagccatag ccagatggtg ctactgatgt actttgtcct
    26461 tgagctgctt gagcctgggc tgcttgctca ttagctgctt tagcggcctc agccttgctg
    26521 gctagttgct gacgaccttc tgtgatgctt gcctgcaaga cagcatcaag atttgcattt
    26581 cctgttgtca aggttgcact tgataaatca tcaaaattag catcagcctt gacttcagcc
    26641 gaaacctttt caccatctac aacaacatcg gaaacaaatt taccgttaac cgctgtaata
    26701 gcagcaatag ctttcttaag ggaatcgact tttgctttcg ccttatcata gtaagcagag
    26761 ccttccaaag ctttcaaggc agcttctaaa tctggcaaag tagcaaaggc actatttttt
    26821 aatttgctct ttgtggcatc tgtataaaaa gtaccatatt gtttttcgaa agctttagca
    26881 gcagccttca agcgcgttgc ttttttagca ctgtcggtct gcaaagaggt ctttgtctgt
    26941 ttacttgctg tttgagttgt tttaccactg tcttgtctca agaaatggtt ccaaccaaat
    27001 acaactgcaa gaatggccaa taatagtaga aataaagcta ttaaccaacc ttttttcgtg
    27061 ttttgtttgg ctggatggtg gctatcttca gaaagaaact gatctctttt tggctcttcc
    27121 ttggtcatct gtggttctgg aatgcccctc tctgatggat ctagatctaa cacagggact
    27181 gtcgcttcca ccggaatccc agttaccacc gcagtagtct ccattggagc taagtcttca
    27241 gctacttctt caaccaaagt gctatcttgc tcagcagact ccgcagacac aggttcgtca
    27301 tcaacaagac cggctttact caatgcttct ctttgttttt tgataaagtt atctaaacta
    27361 gctgtatcaa gctctgtata cttagcatca aacttttgag aagaaacttc gtcacggtgt
    27421 tgcttaatgt acttatctaa aatactatca tccttagtaa cacctgcttt tatctctgac
    27481 tgtttgcgta cagcttcacc aattgtcatt gacttggctt cattaagccc caatgtttgc
    27541 gattcttttg ttacttcgac ttctttgctt tcttctgaca cgcttactac ctctctatat
    27601 cagatgtcgc tttacccttt ccccataaaa ttggtacaaa tcaactttta gggtgccgtt
    27661 ataaagttta cgttttttat cagctttttg cccgtatttt agttcaaaaa gttcatcact
    27721 tgtaaggata aatttgctcc atgttttcaa tggtgcaaag gtttgtccca tttcattata
    27781 caagatgtca accgctttgt catcaagcaa ccgttctcca taaggaggat ttgatatcac
    27841 tacaccatta accttgtctg ttcgaaagtc ttgcagacgc atttgcttaa aggtaatcac
    27901 atcagataaa ccagcttctt cagcattact tttagcaatc tcaatcatgc ggccatcgat
    27961 atcaaagcca gaaatatcta attcgatttc ataattagct tcttgttcgg catcatcacg
    28021 aacttgttgc accatgtctt tatctaccca gctccattct tcaaaagcaa acgaacggtt
    28081 aaatcctgga gcaatattca tcccaatcag ggctgcctcg atgcaaaacg ttcccgatcc
    28141 acaggtggga tcaaccagag gtttatctgg aaaccagtta gataaggcca agatagcagc
    28201 tgccatattt tctttaatag gagccccacc cttttgaacg cggtaccctc gtttaaatag
    28261 gctagatcct gtcgtgtcaa tcataatagt ggcttggtct tttaaaatag atacctcaat
    28321 gttaaacgtt gacccaactt cttgaagagg aactccttct ggcctgtgga aatgtttttg
    28381 cagtttctta acaacagctt ttttggtaat cgcctgaaca cttggctcat tgtgtagctt
    28441 tgacttgaca cacttggctt ttgagattgg aaacttagct cctagcggta aataatttcc
    28501 ccaatccaag gcaaagacac cttggaataa ttcttcaaag gttctagcag gaaattgtcc
    28561 tacgataatt ttgatacgat ctgctgcacg taaccaaaga tttgttttaa caatcgcttc
    28621 tacatcacct tcaaaataaa ctttcccatt ttcaacctga caatcaaaac ctagtgctct
    28681 gacttcttta ccaacgacag cttctaaacc tgcggctgca gttgcgacta atctaaatgt
    28741 ttctttcata tatctctttc ttttaaatca aataaaagct agcaagtgct agcttaacct
    28801 attatgcaat tttctataag ccatgttttg ttccggaaat aactaggaat tatttccttc
    28861 gataatcatc tgtctaccgt ctgttgacag tcaggatagc ttgttcgttt ccaactatcc
    28921 catgccccta ccaaagtttg ggttgctagc ttgaggggtt taccgcgttc cattttttac
    28981 gtttccataa aaactacgtc actgtggcac tttcagaagt actttggcat atcaaacgac
    29041 ttagccattt ccttcgccgt aatgtgtatg cacatcccta ggcttatgtg ttcgcctagc
    29101 acaatcacta ctggcatcac agccagtgct agcatggact ttcctcatag tattaaaata
    29161 ctacgcgatt atccaaaaat tgcacagttt tcattactca ataatttgtt taccaaaaac
    29221 ctctttttcc aatttactaa tacgtttcaa gatgtcaaaa ttagtagctg attgagcaac
    29281 acgagtcggt tgcggtactg gttgttgaac agtcgctgaa actgtatttc tagcttgaaa
    29341 cttggccttt tttaaggctt cgttctcagc ttttaaagct tcaatttgag cattgaaatt
    29401 ttcataatct ttaattacat tatcaagaaa ttcatcaact tctttcttat caaaccctcg
    29461 catactagtc ttaaattctt gctcaaaaat atctttagga ctataaataa tacttgtcat
    29521 tctttactct ccgaacggtc aatcttttta ccaaaattat atttcagtat tattattaat
    29581 gatacagaaa aatagttcaa aaagcaagta tttaaatacc aataccccta aaaatacaat
    29641 gctagctttg tgacatatca tttagccgat caaaggttag caatagcaac tgataatgcg
    29701 gcatatcttt tgctttcttg agaaaatatt ttaagttggt ctcgttttct gtgtcataaa
    29761 aaacataagc cccttctgtc ttttctaata aaaactgata atattgacta aattgcgtcg
    29821 gttgttcgta atttggaaag taatatttta caaagtcaac agccctaaac tgacttaaaa
    29881 cttcttgatt tttttcattc cacctatctc catgcgtttc aaacaagaat atagtagcta
    29941 tctgcaaggg atactcctct tttagctcat tagctacttc caaagcccat tgttcaaaac
    30001 ccaagttccc tgtaaagata aaccaatcca caccattttc caaataacct attaaatctt
    30061 tacgaatagc ctgtttaata attgaaactc gtgggtcttt atggtcaaaa atccctattt
    30121 caaagcttcg gtaacctgta attagaatcg cagtcattag gtgttatcct ttcaaaaaat
    30181 atgttataat aaaagtgctt aaatttttag cattaactag ataatattag gagaacaatg
    30241 gttaattatc ctcataatct tattcgacaa aaagtaagtt ccgttcaaaa gcaaacaaag
    30301 caaaataagg tggacttcgc caatagaggt atgtcctttg aagctgctat caacgcgaca
    30361 aatgattatt atttatctcg tcaaatagct gtcattcaca aaaaacctac tcctgtccaa
    30421 attgtcaaag tggattaccc taaacgcagt cgggcaaaaa tcgttgaagc gtactttaga
    30481 caagcttcaa cgactgacta ttgcggcgtt tataaaggac attatgttga ttttgaagca
    30541 aaagaaacca ggcaaaaaac agctatgccc atgaaaaatt tccatttaca tcagattgaa
    30601 catatggctt gcgttttaca tcaaaaagga atctgctttg tccttcttca cttttccaca
    30661 ctgaaggaga cttactacct acctgctcaa gccttgattt cattttatca gatagataat
    30721 ggcagtaaat cgatgcccat tgattatatc agaaaaaatg gctttaaggt agcatttgga
    30781 gcctttccac aagtccctta tttaaacata attgaacaaa attttttagg cggtgattac
    30841 aattaaaaat ccaaaaatcc ttaagtggct aaagtatgta ttaagtgcaa ttcttagcct
    30901 tattatcctt gttattatta ttggtggtct tttgtttacc ttctacatta gcagtgctcc
    30961 gaaactgtca gaagcccagt taaaatcaac aaactctagc ttggtttatg acggtaataa
    31021 caatctgatt gctgatttgg gttctgaaaa gcgtgaaaat gtaacagctg atagtatccc
    31081 tattaatcta gttaatgcta ttacctcaat tgaagataaa cgtttcttta accatcgtgg
    31141 agtagatctt tatcgtattt ttggtgctgc ctttcataat ctaacgagtc agaccactca
    31201 aggggggtca acgcttgatc agcaactcat taaactagcc tatttttcta ctaatgaatc
    31261 tgatcaaacc ttaaaacgta aggctcaaga agtttggctt gctcttcaaa tggagcgaaa
    31321 atatactaaa caagaaatcc tgacttttta catcaacaaa gtatatatgg gtaatggcaa
    31381 ctatggtatg ctgacagccg ctaagtctta ttatggcaag gatcttaagg atttatctta
    31441 tgcccaacta gccctattgg ctggaatccc tcaagctcct agtcaatatg atccttacct
    31501 tcatcctgaa gctgctcaaa atcgccgtaa cgtcgtgttg caacagatgt acatggaaaa
    31561 acatctgacg aaagcagaat atgaaactgc catcgcaact cccgtcgctg aaggtctaca
    31621 atcactccaa cagcgctcaa cttatccaaa atatatggat aattatctaa aacaagttat
    31681 tgaagaagtc aaaaaagaaa cgaataaaga tatttttacc gctggtttaa aagtttatac
    31741 caatattatc cccgatgcgc agcagactct ttataatatt tatcattctg gtgattatgt
    31801 ttactatcca gaccaagatt tccaagttgc ttcaacgatt gttgatgtga caaatggtca
    31861 tgttattgct cagcttggcg gacgtaatca agatgaaaat gtttcatttg ggactaacca
    31921 agctgtttta actgatcgtg actggggttc taccatgaag ccaatcacag cctatgctcc
    31981 tgctattgaa tctggtgttt atacttctac tgctcagtcg actaatgact cagtctatta
    32041 ttggcctgga accactaccc aattgtttaa ctgggacctt agatataacg gatggatgac
    32101 aatccaagct gctattatgc tatcgcgaaa tgtcccagca gtccgagcac tggaagccgc
    32161 aggacttgac tatgctcgat ctttcttaag cagtttaggt attaactatc ccgaaatgca
    32221 ctactcaaac gctatctcaa gtaataacag tagctcagat aaaaaatatg gtgcaagtag
    32281 tgaaaaaatg gccgctgcat acgctgcttt tgcaaatggt ggtatttatc ataaaccaag
    32341 gtatgtcaat aaagtggaat ttagtgatgg tacaagtaaa acttttgatg aaaaaggaaa
    32401 acgtgccatg aaagaaacca cggcctatat gatgacagat atgttaaaaa ctgttctcac
    32461 ttatggtaca ggtactgctg ctgccattcc tggtgttgcg caagctggta aaacagggac
    32521 ttctaactac actgatgagg aactagctaa aattggtgaa aaatacggcc tttatccaga
    32581 ttatgttggt acattagcgc cagacgaaaa ctttgttggc tttactaagc gctacgccat
    32641 ggctgtttgg acaggttaca aaaaccgctt gaccccagta tacggatcaa gtctagagat
    32701 tgcatctgac gtttatcgta gcatgatgac ttacttaaca aatggttaca gtgaagattg
    32761 gacgatgcca aatggtcttt atcgcagtgg tggattcctc tacttaagcg gaacctatgc
    32821 gagcaacacc gactatacta attcggttta caacaatctt tacagcaata acacgacaac
    32881 agcttctagc caaacgactt cagatgatac tagtagtagc aatgatataa gtaattcaac
    32941 caatacagac aacaatagca atcatccatc taccgatgat aaaaagacaa ctcattaatc
    33001 tctaactcta cttattgtct gtacctacct tttattacat atccatttag ttacttttaa
    33061 tatctacctt aagtgataat ctaaataaaa agcgagtcca cgttctgtga ggactcgttt
    33121 ttatatgaca caaatgactt accacataca atataaaaca aaaaacagaa ttctttaatc
    33181 gtattaaaga aaaggtacaa cgttaaggga attagcaact gatttttcaa acgttaacct
    33241 aaaacaaaat agacttattt aaaattgtta taaatagcaa ctaatgccat aagagagtaa
    33301 acatgaaaaa acacgtttcc atataccgaa gacgtgtttt ttcatatgtc attttcttag
    33361 cataataatt tttttcatgt tcactttctt atgcggagtc caatccgttt gctgttcgtt
    33421 ttgtccagcc tttagatttc atacagtcgc aaagaaagga attagcattg tgctaaagca
    33481 cccattggat cccaaggagc tagtacttgt ggctcttttt cataagccgc taactcgtca
    33541 gctgttaaga attctttacg gacaacaatt tgataggtat attcatccat ccaagcatct
    33601 gaagcaacaa agtaaccttt gtcaccaacc ttctcacccc atgaattttc aaccttccat
    33661 tttaacggtt ttcctgtttc atctaagtca acacctgtta aaaccatagc atgtgtcatc
    33721 aaactttcac tataatccaa acgtccagcc ttatcttgac taagattgat atccatacta
    33781 gcttcaaaat cgtaagtatt agttgccaaa atcccttttt gacgatctga aacttgaccc
    33841 acatcagagc caaaccaaac ggactcacca gcctgcatct gcttgatagc tagttctttg
    33901 aaacgtttca tatcaaggtt gaggtagcga acctcacgac taccgaccac atttcctagc
    33961 atctcaacag tgtatgattt gccataaggc ttatcagcag ttggcgcatt aataacagac
    34021 acataatcag aaagctttaa gccaacaaat ttgtcgtaaa acgcttgcgg tgtcaaacct
    34081 ttctcaacat gatagtggtc atctttatca cggtaggcaa aatcaaaatg acgaggtggt
    34141 aaaccaaggg tcatggccaa gaagttaaaa atttcctgaa gaagctctgc ttttcgatcc
    34201 tcaacttggt ctgccttagc acctgatgca atcaggtcac gaagaatttg agcatcttgg
    34261 cgcaataatt tattcaaata ctggtttaat tcacgactgt tacttgatga gattgattct
    34321 gggtaaacag attttggcac cactccatac ttctcaaaca aggaaaccac catgtcccac
    34381 tggccaccat cttgttgtgg aacatccaag agaaacttaa ctttacgact ggttaattct
    34441 tggtcagctg tagcaatgac ctgctccata aaccagttag ctttttcata cttatcccaa
    34501 aagaaagtat gggcttgtga cagttcaaaa ttttctaatt taaactctgt gattaatttg
    34561 tgtcggaaag tgttcaaggc agcaaacatc cagcagcgac cagatgcctt ttggttagat
    34621 accttatctt tagttaaatc aatagaaaac acaaaatcat tgtccacttc actttgacgg
    34681 gtttctaatg attttagcaa accattatgc gtaacggcat tctcaatagc tgaaaatttt
    34741 gcattggctt cgtaatgagc aaataattgt tctgtaaatg tctctgttaa tgctgacatt
    34801 attgtcctcc taaaatatta agataagctt cacctgaaat aatattggca agatggttat
    34861 tatccagcca ttctattcta aaggattact tctattatag accttatttg attttcttca
    34921 agaaaaaagt taggataacc taactttttt tgttttcttt ttttactctt tgaacatcat
    34981 ttcttatttc caaaaatcat caaaaatggt gattggcagg tgacgcttgt gttgtccttt
    35041 atgccaccat ttttcaatag ttgcttgagc tgctttggaa atcagcttcc cttccaaata
    35101 gtcgtcgatg tcttgatagg tcacccctag ggcaacctca tcagccaagc ctggtttttg
    35161 atcttctaaa tcagcagttg gaactttttc atacaaagca gcatctgctc ctaaaacttt
    35221 caaaagagcc tttccttgac gtttgttaag cctaaagagg ggaagaatat ctgctccacc
    35281 atcaccaaat ttagtaaaga aaccagtgat gttttctgcc gcatgatccg ttccaataac
    35341 agcaccagcc atttggccag caatggcata ttgacttatc attcgctgac gtgctttaat
    35401 attacctttg ttaaaatcag aaatctcaac gcctgctgct tgtagagcct ctacttgacc
    35461 gtccacagct gccttgatat taatggtaag ggtctgatct ggtgcaataa aagccaaggc
    35521 tttttgcgca tctgcttcat cagcctgaac cccgtaaggc aagcgaacag ctataaattg
    35581 gtaagcttga tcacttgttt cctcccgtaa ctctgcaatg gccatctggg ctagctttcc
    35641 tgcgagggta gaatcctgac ctccagaaat gcctaagaca taagttttta aaaatgagtg
    35701 ctttcgcaaa taagctttta aaaaatcaac ggtttttcga atttcttctt gtggatcaat
    35761 gctagccttg acgcctaatt gtcgaatgat ctcttcttgt aatgtcatgt cattcactct
    35821 ttccatgagt atctttacga atgttatcaa tcaaggtcat cttattttgc cacacatctc
    35881 gtgccaagtc tactgggtag tcttgaggat ttaagacacg cttgtattca tcccaaagct
    35941 tgtcaaattc ttttttagca taagtcttga tttcagataa ggtcggtagc tggtaaacta
    36001 attctccctt gacaaaaata tcaactaaga gaggaattgc atcaaaattt ctgacggttt
    36061 tcttaatata ggtataggtc ggatggaaca tctcaatctc agttaattca ttaacattaa
    36121 tatcagtaaa cgtgatatag tcgccttctg atttgccttt ttcacgactg gtgatgcgcc
    36181 aaacttgttt tttacctggt gtggatactt tttctgcatt atttgataat ttgatcgtat
    36241 cacgcatgct accatcttct tgctcaatag agacaatctt ataaacagca cctaaggcag
    36301 gctgatcata ggctgtgatc agtttggtcc caacacccca aacatcaatt ttggcctttt
    36361 gcatttttaa gttgaggatg gtattttcat cgaggtcatt agaagcatag atcttagcct
    36421 cggtaaaacc agcgtcgtct aactgctgac ggactgtttt tgagaggtaa gccaagtcac
    36481 cagagtccaa tcgaacacct agaaaattaa tcttgtcacc catttctttg gctactcgga
    36541 tagctgttgg cacacctact ttaagtgtgt cataggtgtc aacaagaaat acacaatctt
    36601 tatgggtctt agcataagcc atgaaagcat cataatcatt accataggct tgcactaaag
    36661 catgagcatg cgtacctgaa acagggatat caaagcgttt acctgctctc acattacttg
    36721 ttgcatctgc tccaccaatc atcgctgcgc gggttcccca aatcgcagca tctagttcct
    36781 gtgcacgacg ggtaccaaat tccaaaaggg gttcatcctc aatcacagaa cgaatacgag
    36841 cagcctttgt agcaatcaag gtctggaagt taacaatgtt taaaagagct gtttcgacca
    36901 actgacactg acctagaggg ccttctactt gcacaatcgg ctcattagca aaaaccaaat
    36961 ctccttcttt agctgaacgg atggtcaatt ctaatcgtaa ctctttaagg taggtcaaaa
    37021 agtttcctgg ataacccagt tcttcaaggt aagccaaatc tgtttctgaa aattgaaatt
    37081 gctctagata ctccaccatg cgctgtaaac cggcaaaaac agcataacca ttgttaaaag
    37141 gttccttgcg gaaatagact tcaaacaccg catgacgatt atgaatgccc tgctcaaaat
    37201 aaacttgcat catattaatc tgatacaaat cagtatggag agttaaacta tcatctttat
    37261 acataaaggg gactcctttg aattattgtt actattataa catattttaa aaaggactct
    37321 ttggctaggg tttagaaata acttgagtta tcgctaaagt aaaaaaagaa ctgatccatc
    37381 atgacatcct caaataagaa agagttaatg gattcagttc tatatcgcta attattattt
    37441 aaatttgaca ttgctataaa tcccaaaaac aataatccaa atcgttgctc caatggcgcc
    37501 gatataggtg gattcttgta agaaaagaga gataaagaca aaagcaaaga aagcaagggt
    37561 caaaggcgtt gtcactttat attttggcat caaataacca tctgccataa agtccttaga
    37621 ttgacggtac ttccagtgag caatcatggt taaggcgtag atagcaatat atacacctga
    37681 tgaggaggcc gtaatgagtg agaacgcatc tgcaactcct ggtaggatat taatcaaagc
    37741 tgagatacca accacaaccg ctgaagcaat aatggcacga cttggcaccc cttgtcgaga
    37801 taaagtatta atctttaagc gattggtcaa agcgtttgga gtctcattag caatctgata
    37861 gagatgacga ccggttgaat aaagggttga gttaagcgct gacgctgctg atgtcaagac
    37921 cacaaagtta atcaaggctg ctgcccattt aataccaatc aatttgaaca ccatcacaaa
    37981 aggagattca tcaactggta actgatgcca tggcacaatt gccataatag agaccaaggc
    38041 tcccacataa aagatcacaa tacgggttgg aatttcttga atagcctttg gtagaacttt
    38101 tcttgggtta gccgtctcag aagtggtaat tcccacaaat tcgatagctt gataagcaaa
    38161 gaaaaccatt tggaaggcca taaagaactt tagtttccca tttgggaaca tggaaaaatg
    38221 gtcaaaaata ttggaaaggc tagcatggcc tgtgtgagtt tcaaaacctg tcaataccat
    38281 gaaaatagct gttgcaatca aagctaaaat agctaaaatc ttaatcatgg caaaccaaaa
    38341 ctctgtttcc ccaaaaacgc gcacagcaat taagttgatc gaactaagta agactaagaa
    38401 aaccaactga atcaaccagg ctggccagct tgggaaccaa aattgcacat aagcacctac
    38461 tgctgtgatt tctgccattc caataaaaat aagggaaatc caataggata gacccgaaaa
    38521 ataaccccag cctggaccaa tgtatttgga aataaaattg ataaaggtgt gttgatctgg
    38581 atcataatag agcatttcac cgatggcacg catcatcata aacatgaagg cacctgtaat
    38641 catatacaca aaaataatag atggtcctgt tagggcaata gagcgtcctg cccctaaaaa
    38701 gagacctgtt ccaatcgttc ctgcaatcgc aattaactgc acatgacgat tttctaagcc
    38761 ccttaccatt ccattttcta gttcgttatt gtctgtttgt tcttttatag acattctaaa
    38821 ctccattcac taaaatacta tttattatat ccttttttca gaaaattttc aacatttatc
    38881 taggaaagat attaaggaaa actgttcttt atatttctta aaggtcttat gcaatttagc
    38941 ttttttaagg gaaagacaag gaaaaatgaa ggagttttaa ccttatgaag ggaaactttc
    39001 aaggtagtga taaacacctt gccctgcaat tgcaccatct ccaacagctg tcgtgatttg
    39061 gcgaaggtct ttttgacgaa catctccaat cgcaaaaata ccaggaatac ttgtcctcat
    39121 atgatcatct gtgataatcc aaccttcttg atcggtaatt tctagatcct ttaccatacc
    39181 tgtcacagga ttcataccaa catagataaa cacacctcca aaagcgtggt cagtgacttg
    39241 gcctgttttc acattttcga ttaggacatt ggagacctta atatcattgc cttgaatttc
    39301 tttgacgact gaatcccaga taaagtcgac cttatcattg gcaaaagcac gatcttgcag
    39361 tattttttga gctcttagtt gatcacggcg atgaacaacg gttacctttt tagcaaactg
    39421 agtaagataa atagcttctt caactgctga gtcaccacca ccaacgacca aaagatcctg
    39481 gtcacggaaa aacgcaccat cacatactgc acaataagaa actcctcgac tagtatagta
    39541 ttcttcacct ggaacaccta gtacacggta tttagctccc gttgcaataa taaccgtttt
    39601 agcttcataa ctagcatctt cagtcaacac acacttatag tcaccaaaat tttctatttt
    39661 ttgaacaata ccataaatgt tttcaacgtt aaacttctct aaaggttcgt acattttcat
    39721 agctaattct ggtccagata tatgatcata tcccgggtaa ttctctatat caaaagtgtt
    39781 gttcatctga ccaccaggtg ccccttgttc aataatggca acagataaat tacttctagc
    39841 agcgtataaa gcggcagtca ttcctgctgg tcctgaacca ataattaatg tatcgtacat
    39901 gatttttctc ctttaatcta ctcttgccaa tattttagca atgataatcc cttcttgcaa
    39961 tgattaggat tttatgacaa ccaaaatact cataaaagca aacgataaaa ttgggatggt
    40021 taaaatagca accattagca tctcataaag aaaagcttgt ctttcaatca atgttttatc
    40081 tcttttggtt tttgctcgcc ataaagtcca tattaaacaa attaaaatca tagtaaggct
    40141 tgagagaatg agacctttta cataaaggct aaagatttct actaacatat ttccacctag
    40201 tcattatttc tttcccataa gtttttctaa aaaacataac aagaaaagcc caggaatacc
    40261 tagacctttt tattataaca aaagaatatc attaaatgta tgtttttgaa tagcttgcaa
    40321 aaaattcttt ggttcgttct ttttgaggat gtctaaagac ttcttcaggt gttccttgtt
    40381 ccaagatttt cccttgatct aaaaagagta ctctatctgc cacttggtaa acaaaattca
    40441 tgtcatgact cactaaaacc atggtctgtc cggatttagc agcatcagta atagactttt
    40501 ccacttcgcc aactaattcc gggtcaagag ccgaggtcgg ctcatctagt aataaaacat
    40561 ctggtttcat agccagagct cttgctaaag ctacccgttg tttttgtccc cctgataaat
    40621 gacgtgggta atgatgtttt cgatctgcta aaccaacctt agccaattct gcttgcgcca
    40681 gcttagtcgc ttcttggtca gacagttttt tgaccacctt aagaccttct ttgacattct
    40741 caagggctgt acgacgctca aaaagattaa attgttgaaa aaccatggca agtttccgac
    40801 gtaaaataag gacttgctct gtggtaatgg tctcaaaatc aaccgtaaag tcaccaatgc
    40861 taatggatcc tgaatctggt ttttccaaat agtttaggct acgaaggaag gtcgatttcc
    40921 ctgctcctga agcaccaact aaagcaatca cttgaccttt ttcaatatca agagccaaac
    40981 tatctaaaac tttttgccct gagaatgtct tgctcaaatt tctaattgta atcatcaacg
    41041 caattctcct aacttttcat ttctagcttg ttctggtgct ttgatggcca tcttgttttc
    41101 aatcaagcga cctacttgct ccatcaaaat actgatagac caatagacaa gagcaacaga
    41161 gatataacgt tcaaaataac ggtaatctga tccgcctaga atttgagcct gggcaaacat
    41221 ttcgacaatc cctgcattaa aggcaagcga tgttccttta gttaagccaa ttaacccatt
    41281 aatcaaggtt ggaatagcca caacagttgc attaggaata atgacacgac ggtaaacctg
    41341 cacagaagtc atgcctagac tttttgctgc ttcaatttca cctgtatcta ctgataaaat
    41401 ggctgcccga atagtttcac tagcgtaggc tgcttcatta aaagcaaagg ctgtaatggc
    41461 aaaaatagaa gccggaattg cattaacatt ccaatcaaag ccatacttct gattgagaaa
    41521 ttttagaaag aggggaatac cgtagtaggt caacatcaac tgtaccaaaa taggagttcc
    41581 tcgcaagaaa ctcacaaaaa tagcttgaat agggtatagt agcttcactt tattaatttt
    41641 gacaagggca aaaatcaaag ccaaaaccaa gccaaaggtt gctcctgata gtgtcaaacc
    41701 aagcgtaatt ggaagccgtt ggataatatt tggaatggca tcaaaaacag catgccaact
    41761 aaaaagtttt ccatgtggaa tcggtgagat gaggtaatca taaaaagccc aaccactggt
    41821 taaaaacact gatgtcatgt atttcccctt tgtatttgtt tgtcttaata ttctaacact
    41881 cttagaccca catgtaaaat agtaaatccg tattatagca ataagcaaaa gctatgatca
    41941 ctttttgtgt taacaaatgg taaacaatac aagtagcagg tgtaaaaaaa gcaagattag
    42001 atgccaattg atcacttgct tgctctttgt tcttaaaaat gttgtttttt ggcgttacgc
    42061 tcagcgcggc ccttagcacg attttcagca cgacgttctt tgcgacgttt ttcatcaacc
    42121 gcccactgaa tttttttctt gtaacctggt ttgacttttt tctttttctt tttgaccaaa
    42181 ccaatcattt ctgtgtctaa tttttgatag gctttttcac ggttttgacg gcgatcacgg
    42241 tcataggtat cttgaaattc tccatttttg agcaccttcg gtgtaaaggc aatccccatt
    42301 ttttccagct ctttgatatc tgagtcgtca cttggctggt aaagtgtaat ggcagttcct
    42361 gccataccat ttcgacctgt tcggcctaca cgatggacaa agaaagacaa gtcttgtggg
    42421 atggcgtcat tgatcacatg gctgacccct tcaatgtcaa tcccacgcgc tgctaagtct
    42481 gtggcaacaa tgtattcaaa gtccagtttt ttgacttggt tcatgatgcg cttacgttct
    42541 cttggaggaa tgcccccatg aatcttagcc acttttaagc cattagctgt taaaaaggca
    42601 tgcaaatcat ctgcgcgttc cttggtattg acaaaaagca tagccatata aggctgcatg
    42661 gttttgagaa tctctaacag ttgaccattc ttatcacgcc cttttgtcga cacaagccag
    42721 ttatcaatgg tatctgcgat aacggtcttt gtcttgattt gttcaataac aggattggtc
    42781 aagtattttt tcaaaaaggg ttgtaatttc tgtggaatag ttgctgagaa caccaaaatc
    42841 tgaacagatt ttggaagcga agctgcaatc ttatctaccg tatccaaaaa gcccatgtcc
    42901 atggtcatat cggcctcatc cacaacaaag gtcgttgctt tatgaatcgc taaatcacca
    42961 gacttgacca agtcataaat acgacctggg gttccgatga caatatgcgg ctggctgcct
    43021 tttagttttt caatctgacg gagtttgtct gtgcctccaa catagttggc caaacgaatc
    43081 tcttcttgga agtgcttagc aatctgttta caagcatcaa aaatttgagt tgctaattca
    43141 cggctaggtg ctgtaataac gacttgcact tctgctttag cttcatcaag tttttcaaaa
    43201 atgggcaaca aaaaggtgtg ggttttccct gaacctgttt ttgattcccc aactaagtca
    43261 cgaccggagt taacaatagg aatcagccgc ttctggacct ctgttggatt gacaaagcca
    43321 atttcttcca gcgcttgctg aacgtattgc ttaaaatgat aatctttaaa tgacatgttt
    43381 tacctcgttt tcttccatat tatatcatta ttgttagaga caagcaaaag gagtgggaca
    43441 acactcacaa aatcagcatt tgtgggtcat ctccactctc ttattgatga tgttaatcaa
    43501 aatgctattg gtgactattc ttgataatcc cccttagaac acgtataaga tagctaaaac
    43561 tagtaaacta gctagacttc ctactcccca caaaaaagca tctacctgcc attctgacca
    43621 cttcttgcct ttaccagaca agcctcccaa ttccaaatgg tggtggaaag gcgtcattct
    43681 aaaaatacga cgaccttctc catatttttt cttggtgtac ttgaaatagg acacttgcaa
    43741 catcacagaa cttgtttcaa gaacataaac gatcccaata atcaggagag tccattcttg
    43801 acgaagcgca atagaaatgg cagccaacat agctccaagg gctaaactac ctacatctcc
    43861 cataaatact ttagcaggtt tgtgattaaa gcagaagaag ccaagcaagg ctccaatcat
    43921 tgctccaatc agtaacaaaa catcaaattg actctgaacg taggcaataa cgccgtaagt
    43981 cactagacta atcaccactg agatagaagc taagccatcg ataccatctg tcaaattaac
    44041 ggcatttgaa aaaccaacca cccaaaacaa aacaaagaat aggtagaaaa ttcccagcgg
    44101 cagctgataa ccaaacacat taatagagga aatgccactt ggactaacat gtaaaaaata
    44161 gaacatcaat cctccaacca actgcaaggc taacttttgt ttggctgtca atccttcatt
    44221 gatttgttta aaaattttta aaaaatcatc caaaaatccg ataatcccgt aaatgacaac
    44281 aattgataaa atgcctgaaa tcaaagctaa actttgagtg tttttgatcg aaaatagact
    44341 aaccaataac gatactgccg tagctactaa aagaaaaaca gttcccccca tagtcggtgt
    44401 tccagcttta gctaaatgtt gcttgacatc ttcatgcatt tgttgcccac caattttttt
    44461 caattgatag aatttgataa aataaggcat tgtgaaagca gataccataa aggatatgat
    44521 tgctgcaata agggttaaaa acatgttaat ctcctaaagt aatggtcatt ttttttattt
    44581 ttttcaagga cttaccaaca tcaacacttt gtttcataac acgaccagaa tctgttcctt
    44641 taaagctgat gtctattcca gtccatttag caaaggtttt aacattggat tttgtccagc
    44701 catacatgtc tggtacctcc acaaaacggt ctgataatat gagaacttgt tggttttctg
    44761 ttaacgtttg accgggctga tgcgatactt ttttgatctt gctgccagta ccaaggacaa
    44821 ctggctggac aagatttcga cgcaactcgc ttgatgtctc accaggattc tttcctacaa
    44881 agtttggtaa tttataagtt gtttgacgat tagcatctga tactactggc ttagttagtg
    44941 tatcttgcat taagtatgct tcttccaata ctgggttaac cacatcttgc caaaaaaggg
    45001 gaccaaaatg ttgtggttta gtcatagtaa catacatcaa aaagtctggt ttatcagctg
    45061 gcaccattgc cacaaccgaa tagacatagt tagtcaatcc accatcttga taaccacttc
    45121 catcttctga accaatttgt gctgttcctg atttaacagc aacaggtaaa tcacccactt
    45181 taataattgg tccaaatgtt tttgaataga gtgttccaaa ctcagggtct gttcctacac
    45241 caatcatgta ttgtcttgtt tcactagcgg ctttttttga tacaggtttt ccaacaattt
    45301 ctttatttgc cgttctaaaa cttgctgtgt taggatcata aatttgactg ataaattgtg
    45361 gctctaacat ctcaccatta ttagaaatag cagtaaaggc tctaagcatt tgaatctggg
    45421 ttacagaaat cccttgacca aaagcgctca tagcttgagt cacgatatta tcagaaggaa
    45481 atatacctgc gtcttcatct tttaaaccaa aacgagtagg aaaaccaaag cggaacttcg
    45541 tcaaataatt catccatttt gcattaccca ttttttgttc aagtttagtc atcccaacgt
    45601 tacttgagaa ggcaaatcct tgtgcataat tcatgtactg tcctgtggaa atgccttcat
    45661 taatagacca gtcttgaata gtagcatctg caattgttaa accattagca ttgctaaagg
    45721 tttcgtttgg gttgaaaact ttatcatcaa tagccgctgc cagagtcatc actttcatgg
    45781 ttgagcctgg ctcaaaattt ccttgatgaa gtgcactgta ccatttgtag ttcgtatttt
    45841 caagtccttt cagagtatca gcattataag tagggcgttg tgttgttgcc aaaatttcac
    45901 cagttttagc attaacaagt gttgcactgg ccaactgacc atttgatttg gcttgaaaaa
    45961 catccatctg ggtttctaag aaggtctgga taggctcaga tagcgttgtg taaatatctt
    46021 tgccatcaat agctttcttg acagtcttac ctgtacccaa gagtgtggtc ccatttcgat
    46081 ctttttgata agtaataaca ccatcttgac ctgataaaat tttatcaaaa gaagcttcta
    46141 gacctgtttt tccaactaaa ctcttaacac ctgtcttttt atcttctgtt agagatgcca
    46201 agcctataaa ttctgaagca aatgtcccgt ttggatacat acgaccagga ctagttgtga
    46261 aagcaattcc cttgattttg gcatcttcca tagccttttg aatagtagac atagtactat
    46321 atgaaatgcc agaccctgac ggtccaaacg agacttggaa aagtccttta cgcttaagct
    46381 gtttaattac atctgttttt ttcattccca gatgcttttt taaaatatca gctactgttt
    46441 catactgaga aggttgtaca tataactttt catctgaagc cgagacaaat gatttatcca
    46501 aaattgcgta tatgctataa gtcgtagaat ccactgcaat agctgtacca tttcgatcat
    46561 aaatggtccc acgcttagct tggatcgtaa cggtttcttg ataaaccttc ttcgcccctt
    46621 ctgacaaact aactccaaac ttttgatctg ttccaataat aatcatgaaa ttaataatga
    46681 aaataaagaa aataaagata gttaagagca tcatattttg tccaactcga acgcgatttt
    46741 cgactggagt tctcctatcg cgcacaacat aatctaaaac atatttttgc cattttttca
    46801 tagattactc gactttcttg atattattat tacggttgct taagcctgct ttaccagcaa
    46861 tatctataat acgatcacgg cgagataact catttacttc ttgcttggca ttattaagct
    46921 ctagtttttg atccgaaata tgactattta aactagtgat ttcttgttgt aactgcaact
    46981 tacgactttg caggtaaata atacttactg ccatcgtaat cgctgttaca atgatagcag
    47041 tataaaaagc cttctcaatt ctagagaaag tttttattcg tttttgcaag gcatttgtaa
    47101 ctgcctgagt tcttttttca tttgtcatag gcttatttcc gaattttttt ggcaacacgt
    47161 agcttggctg agtgtgccct tttattagct gttaactctg aatgactagg taagatcggc
    47221 ttacgtgaaa caagttcaaa cttaggtttc atatcttcag gaattagagg aagccctttt
    47281 ggcacatcca ccgtactagc ttctttaaac aactgcttgg ttaggcgatc ttccagagaa
    47341 tggaaggtaa tgactgagat acgaccatca agggctaata attccatagc gtcctgaata
    47401 gattcatcgg ccgctcccaa ttcatcattg acttcaatgc gaatagcttg aaaaatctgt
    47461 ttagcagggt ggcctttttt cttcaactct ttagctggct ttgctgcctt aatcaattct
    47521 gccaactctg ttgttgtctc aataggctta atagctcttg cttgttcaat ttttcgagca
    47581 atctgcttgg agaatttatc ttcaccatat ttgaagaaaa tcttaaccaa atcattgaat
    47641 ggataggtat tcaccacttc gtaagctgtt aagagcgact gacgatccat gcgcatatcc
    47701 aatggagcat cttgtttata agaaaaccct cgttctcttt catccaattg cgggctggaa
    47761 acaccaaggt cgtataagat accatcaatt tcatcaactc caagcgctgt taaacgtgct
    47821 ttgaggtgtc taaaattatc tttaataaaa gttacctgtc ctttgtcaat ataagatttg
    47881 agggtaactt gtgcattgtc aatagccttt tggtcttggt caaaacaata gaggtgccct
    47941 tcttcaccaa gtttggacaa caaataagct gagtggcctg agccacctag cgtcgcatca
    48001 acataaatcc catcaggctt tatgtcaagc atgtccactg tttcgtgaag gagtacggtc
    48061 acgtgatgaa attcttttgt cataacttta attgtaccat acttcaaaag gtttagaaat
    48121 gaaaaagtaa gagaaaagga tttcattctc gtgggaatct tcctcttctc taatcttgtt
    48181 ctttttgttc gctatcagcc aacttagcaa gcactgactt agccgctgcc tctagaattt
    48241 caactacttg taaaaaattt ttagcttctt taatcacaca acaatctgtc agcaggttgt
    48301 ctaaccaaat atcaaagatt ttatcccaac tcatattcgg taagtcagct aataatagcc
    48361 tatcgacgtc tgccagctat cttcggcagt tttgaagagt aacttgtaag tctattaata
    48421 attggttgac cttgctcatt tttcgacgtt tgatccagct gacaagcata ccgtctccaa
    48481 aaagatcaaa atagccccaa tttcggacaa ttttcaattc caaatgaatc acctgaatct
    48541 gatgtaaaag ttcttctaaa gcaacctttg cttcttcttt ttctctttca ttagtcatta
    48601 agggaccttc tagtagctta ttctctgata tgtccatccc cattaatata aaatttagtg
    48661 ctggtcaagg cttctaagcc cattggccca cgggcgtgca ttttttgagt agaaatccca
    48721 atttcagcac caagcccaaa aacaaaacca tcggtaaatc gtgttgaagc attgacataa
    48781 acagcagcag catccactaa atcttgaaag gtctctgctg ccttaatatc ccttgtgatg
    48841 atagcttcgg aatggtgact agtatgctga tttatccaag aaatagcttc ttccaaagag
    48901 gaaacaacct taacagacat gatataatct aaaaattcgg tctcaaaatc ctctgctttt
    48961 gcaggcactg cctgctcaaa taacggcaaa gccttgtcat ctgcccgcca ttctactggc
    49021 tgaacctgat tgatcgcttt ttcaagcata ggaataaacc ttgctgctac agcttcgtga
    49081 attaccaatc cctcagctgc attgcaaaca cttgggcgct ttgttttagc gttgataaca
    49141 atattagtag ccatatctaa gtcagcttga gcatccacat agatatgcac attccccaca
    49201 cctgtttcga tgacaggcac ttttgctttt tccttaacgg tctgaattaa tttagcacca
    49261 ccacgtggaa tcaacacatc cacatagtcc gttgcctgca tcaattcttc agcaacagca
    49321 tgtgagggat cctcaactag ctggacagca tctggggtga tccctgattt ttccagactt
    49381 tgtcggatca acttcaccaa agctttattt gagtgaaggg catcttttcc tccccttagg
    49441 atgatggcat tattggtttt gaacgccaga ctaaaagcat ccactgaaac attcgggcga
    49501 ctctcaaaaa tcatcgcaat cacccctaga ggaactctct tttggaggat tttaaggcca
    49561 tcgaggttag tatagccctt aatgacttgt ccgattggat cagctaagtc agcaacctgt
    49621 tgaactccct gtgctatcgc tttaatccgt tctgaagtta agcgcaagcg atccatcatg
    49681 atgtcagaaa taccatgttc tttagcattc gctaaatctt tttggttagc ggctaagaga
    49741 gtctgtgtat cgtcaactaa tgcctttgct aaggtgctta aaaagcgatt tttaatttgc
    49801 gtcgacaaag gtgctattaa aagactagct tgttttgccc tttgccctaa ccttctcata
    49861 tcagtcatgt gttacctctt ctatctgctt gaaccaggtg cctagtggtt gcccttcaag
    49921 cactcttaaa atatctctgg gattagctcc attcatcaag accatctgtc ctttgttttc
    49981 aaataccatc tgagcagact gaattttgct aagcatccca cctgtgccaa atttactgcc
    50041 cgcaccacct gctgacgcaa tgatttcttg cgtaatgact gcaacatgac tgcgtaactg
    50101 cgcatcctca taaatagtag ggtttttatc aaaaaggcca tcaatatcag acaacatgat
    50161 taataaatca gcttttgtaa taccagcaac aacagcagat aaacggtcat tatctccaaa
    50221 tttagtcgca tgatccattt catccacact aaccgcatcg ttttcattaa caatcggcac
    50281 aatgcccaaa ctaatcagac tttcaaaagc attggtaaca ttggctagac tttctgggaa
    50341 aaccaccaca tctctcgtca ataaaatttg tgacacgttg gtttggtagt gtgcaaaaat
    50401 ttgtgaataa agactcatca tggccacctg accaacactg gaaactgcct gttgtttagc
    50461 aagattggtc ggacgttttt ccattttcaa aatatctagt ccaaatccca tcgctcccga
    50521 tgatactaaa ataacttcct tgcccttatt catcaaactt gaaatcacaa aagccagttg
    50581 gtcgattttt tctaaattga ttttacctgt tggtagcact aatgaactag tgccaatttt
    50641 aattacgata cgtgttacat cttcaaattg tcgtttcatc atacccaaat tatagcataa
    50701 aaacagcccc agaggactgt ttttccgaat aatgatctct cttcgttaaa gcttctctaa
    50761 gcttttccag aaggtttttt gaatccataa gtgagcaatc cctaaaacca ttagtgtcag
    50821 acaactcaat agaatactaa tcaacagagg ttgttggata atattggcaa tgataacagc
    50881 tccaaaacct actacacctg tgactattaa attaccaaag ataaggccca ttgttagcca
    50941 ctgcccattt cctctggtaa agagttgtgt catgtcttgc cattttaaat ccagaagccg
    51001 gtagtcacga cgatacatca attccccttg cacaatcaga gacagggcgt agccaagaca
    51061 aaaagcaatc gttagaagag gatgcaggtg caacacaaag agaccaaaca caagataaat
    51121 caccataggc acaatcagtt gcagaccgac gagcaagcaa aatttatcca gcaagaattt
    51181 ttttaacgtt attggtaagc ttttaataaa ggtaaagtta tccttttcaa gtgaaatacc
    51241 tactccaata aagctggttg gtgttgcaca catgacaccc aaactgaccc caaataataa
    51301 ggccacccca aagtaatctg gggaaatatg cttaaagaaa cctgtgccac gtgacaaact
    51361 tggaccgata aaaagcatca catacatcag gggcatgaga taggtttgtg tcagtaaagt
    51421 tgcattttgt aacgttaaaa gatgatgttt tcgcaacaac tgcgtcagtg attgattctg
    51481 atgaggacga ttaactggtt ttttagtttg cttggctttg ttctcgttac taatataaaa
    51541 agcctcacga taataagttg gcatcacttt tgtgacaata ccatatacca tagctaaaat
    51601 cagtagcaat ggcaaccaaa agttaaggag ggccgcagta gaaaacggtg cctgaataac
    51661 atcatagaat cctttgaaat acggaatagt tgggtaatca gtaaatacgc catccgtcat
    51721 cgtacgcttg ttgttactaa tattaatcgc aaaaattaag acgaaagctc caaaagttga
    51781 gacaaacatc atgatagttg aaatgagttt ccgcttgcga ctccttacaa tgattttgcc
    51841 cacccaagca ttgatataaa tagctaatac catcgaactc actagtaaca ctaaaaagag
    51901 cacaatagct actaaaatag acaaaggatt tcccaatagt tgccaatagg caattaagag
    51961 aagagagata agaggcatca aaaagacagc acccatccct agcgacgaga caatttttgc
    52021 aatatagagt tcttctgacg ttactggtaa gtgaatataa agttttaagt cattactttc
    52081 ataaaaaatg gtgtaaagag agctaaaggc tgtcaaggtt gacatgataa aaaacatagc
    52141 aacgtcaaag gagaaaagtc ctggataatg actgaaatcg acaccaataa acataaaaag
    52201 gtaaatcacc aaaaacatgg caatcattaa ggcctgttgc ctcatcatgc ttttataggc
    52261 tttgaagttt tctttcgggt ggttttcctg acgctttttg aggttagcta aactttgtgg
    52321 attggaataa agaatgttta tcttgataag ttcccaaata gtagaccaat tcatcccatc
    52381 acccctcttc ttgcgcctta cgacctgcga gttcaaggta gatgctctcc aagtctttgt
    52441 caggatggtg ttctttcaac tcatcaatcg ttccaacaaa aatcaatttc ccttttttta
    52501 gaatcccgat acgatcacat aactgctcag cgactgatag cacgtgagtc gaaaataaga
    52561 ccgtatgtcc agaagctgca tgagctttca tcatttcctt aaggtcaaaa gaagcctgag
    52621 gatccaaacc tgttaatggt tcatccaaaa tccagatgtt aggatttgat acaagagcac
    52681 caatcacaat cactttttgg cgcatcccat gtgagaaact atcaatggtt tgattaactt
    52741 cttccttcag ttcaaaaagt gttgtcagct gtgctaaccg ttcttctcgg tcctcatctg
    52801 acaccccata aattttagct aaaaactgcc aatactcatt tggagttaga ttcaagaaaa
    52861 tatcaggaga atctggcaca taagcaattt gttttttgat agcttctcta ttttctgtca
    52921 gaagttgacc atccacaaat acttcgccat aactcgcttc gataatagaa gtcaaaatgc
    52981 tgatggtcgt ggttttacct gcaccattat gtccgataag gccaaaaatt tcaccgtcat
    53041 tgatggtgac gtttaaatcg ctgagagctt ctttgtcgcc atacaacttt gaaacatgtt
    53101 taaattctat catggtatcc tttttccttt tcttctcttt ttctccctag actgatgagg
    53161 cttcctctaa aatatacttt tccaatgact gcttaaaacg gcaaagcgat tttggaagta
    53221 aaatgtcatt atcaagtaag taattatcca catcttggtt tagttggtag gcaacaagaa
    53281 gtgggttact gtgtttaatt aatctattag aagctgctaa aagtagctgc gacaaggcca
    53341 cattttcacg gttttctgga taatcataag cctgtctaat cacatcgtat aagcgctgtc
    53401 gtttcttttc catttatact cctttatttt ttgtactttt acgctaatac aataacaatt
    53461 aaattataat ttttatgaat cgttttgtca atgacttctt atcaaaagaa gtgtattagg
    53521 cagtttgagg aaaagaaaga actggttatt ttattttaaa aaaacagagt aaatcatttg
    53581 atttactctg tttgggatgt gtaacctaga gtgatttgta taactcagtt gcatttgcca
    53641 cagtgaaacc atattcttcg aagatacgat ttcctggagc tgaagcaccc caagtgtcaa
    53701 tggtcaatgt ttttcctgct aggccaacat attttgccca gccaaagctt gaacctgctt
    53761 cgatagcgag acgtttagtc acagctgctg gtaggatgct ttctttatac tctgctgact
    53821 gttcgtcaaa gatattttgt gatggcatag atacgacacg cacatgaatg ccttctgctt
    53881 caagagcttc ttgagtatcc attgccagtt tcacttctga acctgttgca atcaagatac
    53941 cttcaaggtc gcctttggct tctgacaaga tgtaagctcc tttgttaaga ccatcttctg
    54001 ccaattcttt tgtgccctca agcactggaa ggttttgacg cgtcaataca agcatggttg
    54061 ggcgatctgt ttcagcaatg gcacgtttcc aagcagcatt tgtttcgtta ccgtctgctg
    54121 gacgaataac gttaaagtta ggcattgagc gaacacttgc caattgttca attggttcgt
    54181 gcgttggccc atcttcacca acagcgatag aatcatgtgt catgacataa actgttggca
    54241 agttttggag cgctgccata cgaacagctg gaagaagata gttagagaag acaaaaaagg
    54301 ttccgccgta aacgcgtgtc ccgccgtgaa gggcaatacc gttcatggct gcagccatgg
    54361 caaattcacg aacgccaaac cagatgttac ggccttcgta gtgacctggt tggaaatctg
    54421 tttcagcctt aaccattgtg ttgttagatg ctgaaagatc tgctgatcca ccccagaaag
    54481 aggctacttg ttctgagatt tgttggatgg cttgttgact ggatacacga ctcgccattg
    54541 aactaccaag ttcgtgcgct tcaagttcta cttgagcagc ttcgttagta aaggcttttt
    54601 ggtattctgc tgctaattct ggatattctg cttcataaac tgcaaacaag tcattccagg
    54661 cttgttctgc tttttcacca cgcgcttgaa gaccttgagc aaagcgctct gttacttcag
    54721 caggcacttc aaaatcttga tgagtccatt ggtaagcttt tttggcaaaa gcaatgcctt
    54781 ctgctccaag aggagcgccg tgaacagctg aagttccttg tttttcggca ccaaaaccaa
    54841 taatggtttt gacttcgatg atggttggtt tctcagtttc agctttagct gcttcaatag
    54901 cagctgcaat ttcttctaaa tcatttccat ctttcacaag gatatgttgc caaccgtaag
    54961 cttcgaaacg tcctttcaca tcttctgtga aagccataga ggttggacca tcaagagaga
    55021 tgtcgtttga atcatatagc aagaccaatt tcccaagttt taaatgtcct gccatacttg
    55081 ctgcttcttg gctgacccct tccataaggt caccgtcacc attcaaagca aaggtgtagt
    55141 gattaacgat gtcaaagcct ggtttgttaa atttagctgc taggtgagct tctgccatgg
    55201 ccataccaac ggcatttgcg atcccttgac caagaggtcc tgtggttgct tcgacaccgt
    55261 ctgtgtgatt cacttctggg tgacctggtg ttttagaacc ccattgacgg aagttcttta
    55321 aatcttctac agataaatca taaccagcta agtgtaacaa gctataaagc atggcacttc
    55381 catgacctgc tgataggata aaacggtctc tgtttgacca attacggctt gttttgggat
    55441 tgatgttcat gaagtgattc caaagaacat aggccatagg tgctgccccc attggaagtc
    55501 ctgggtgtcc agaatttgcc gcttgaatgg catccattga tagggtgcgg acagtgttta
    55561 ctgccaactg gtcaattgca tcaaatgtca taagtaaaac ctctctgttt attacaacta
    55621 aaattaaacg ttttctattg tctattgtat cacaaaaata gacgcttttt tcagaaaatc
    55681 ctccaaagtc cctaaattct ttttctctat tttgccagaa aaaaactagt ttggacatca
    55741 ttggtgaatt cttttggacg atgaatataa gagagcctgt tgacacagta gccacagact
    55801 ctttagcctt attttttaaa ggaagcccaa tcttccataa aggttttcaa accatttgtc
    55861 gttaagggat gttgcgtcat cttagcaaac aaggggtctg gaatcgtcgc aatgtgtgcg
    55921 cctaatttag caacagcttc cacatgggct gttgtacgaa tacttgctgc gatgatttct
    55981 gcttggaaat cgtacaagtc aatgatttca cgaaggtcgc tgattaattg ataagcatct
    56041 gtgccaatat cttccaaacg accgataaat gggctaatgt aagttgcgcc tgctttcatt
    56101 gccattaaac cttggcttac tgtgaaaatc aaggtcacat tagttttaat cccttctttt
    56161 gaaagaatgt ttgttgcttt taacccttct gtggtcattg gaattttaac gacgacattg
    56221 tcatgccact tagcaatgct tctagcttct tctaccatag catctgctgt taaccctgtc
    56281 acttcagcac tgattgggcc atcgacgatg tcacagattt ctttgataac tgtttcaaaa
    56341 tcacgtcctt cacgtgagat aatggttgga ttggtggtga caccatctac aacgccaagt
    56401 tcattaatcg ctttaatagc ggctacatta gctgtatcta ggaaaaattt catttcttac
    56461 ctccaaaaat tttcgatttt gttaagctct atttgataag ctttttcaaa tcatctacct
    56521 ttagactatc ctactttatt attataaaag tgtaacagtc cttagaaaag accaagtatc
    56581 acacagtttt gtgtgcaaaa ctagacttag ctgctgggct gagtgagagt tcctcttctc
    56641 gtgtattttt ttgctggaaa aggtctttga gaaaagcttc taaggcagtg agttcatagg
    56701 gggagctata ctgttttaac cggtaatagg gtaaatcttg tctcggtaaa tagacagtct
    56761 gataggtaat cagacagtca taaacttttt gatgatcata gggcattaat tgaaaatccc
    56821 tacgatgccc caaatgacgt ctaatggcca attccgcaat ggctgcttcc accttatttt
    56881 gccccaaggc aagccctact aaaagaggct catggtggcg ctcaatggaa aaaaccaaca
    56941 atgctaaaat gtcgtcactc aactgctgac tgaaatccgt ttcctgaccc atttgcagca
    57001 ctaaatggtt tatgataacc cttaaaagcg ctcttttatc ttcgcctact aattgataaa
    57061 ggtattggct attggttggt tggctaagga tagctccttt aaaaaagtaa gctttggaaa
    57121 aaaatatccc caagccataa atgatttcct cctttgtctg atggataatc acatgagcct
    57181 tctttaaaag ccataaggct tctgaaatgt gatcagcaat aggacctcca aaacccaaac
    57241 tatacttcat gctggcaata ggaagtagag gataagcatg caaaaagaca aagaggctct
    57301 tagcttcaaa agcatcaaat tcaagggcat agcgtcttaa gtaatgtaaa agcatgcttt
    57361 ctaagcgctt aaagaaaata ttagatgtca taaagtcact atctcttaaa aaatgatcat
    57421 tgtagccttt ttgaaaggac attcgcgctt gcgaaatcgc caaccaaatc aataattgtt
    57481 ctaaggcttc tgccgataat gactggccaa tcagccgctc aattaaggta gccaaatgcg
    57541 aagcgtctaa ctgattgacc aaggcgtcta tgccttgtct ggtcaaggta tgacggaaca
    57601 attccaaata gaaataacgc cactgaagct cacttcccag ttgtctgcct tgcgagagcg
    57661 ccagatcaaa ttctgataaa agctggttga ggtgagctag ttgtctgttt agagtagctt
    57721 cactaaccat cagttcaacg gataagttgg tgatgttaaa gtgttcatgg cagtacatgt
    57781 aggtcaatat ctgataggca accgattctt tgagaagcag agctaccaaa tcctcccaat
    57841 ggaactggcc attttctttt aagctcagac tgtctttttc taaaagtaat tgacaggcta
    57901 aaccttgttc tcgacacaaa tgatttaggt tgtcaatgta ttttaatagg gtcactttag
    57961 acaagtttga tagcctcatt aggtctttta gccttaacgt ttctttagca tgataaaggg
    58021 tcaccaagag acgatattga gcttttcgtt ctttatccat taagtcttca atcttcatgg
    58081 cggagcctct tttcaaataa tttgagacaa gcttcatgaa gatgataagc caaatcactg
    58141 tgaccttgta aaaagagaaa atcttgaaat gctaagtcac cgtctgtaac tttcagagcc
    58201 agagcctgac ctaattgatt ggcgatgaca agagcattgg ttttggatag gagctgagcg
    58261 cctattaaaa tcccatccgt ttttctagct attaatttca gccaaaagag gtttttagaa
    58321 tccccatttt ggtacaaata gctacacgta tccatataaa gctctgcttc ttcttctgtc
    58381 acaccaacac tcgcgcgata ataaccaaag tgagaacttc ctaatacctt gaccgtctgt
    58441 aatggaggaa taggatatcc agctaaatgc agagccagag cctgacctgt cttcattgct
    58501 tggttaatca aaggtgtata gtaatccatt cccaatatac caaaatacaa tgaaaccatg
    58561 tctccaatgg catagatatt agcctggctg gtctgtaagt tttcattgac caaaatggtc
    58621 ttatccagag cacaagccac ttgtccttgc aaaaggtgtg tatttggcct aaagttaatg
    58681 gctaaaatag ccaaatcacc ttggaaggtg tccccttgct cggtatgagc gacaactttt
    58741 ccctctatct catggatagc cgtaacacgc ttattattaa taaaggtgac atggtgagtg
    58801 gacatttctg ccattacagg ggctatcagt tctgcgtcag tctgatagaa atctggacgt
    58861 tcggctgctt caatcagttt gacccgtttg ccttgtaagg acaaactgta ggcaaggtct
    58921 aagccaatca agccggcacc aataaccaag acctcttggc tagcctcaat cagttttaaa
    58981 ctagcttggc tttcttcata atatttggtt accaaaactt tgttggtctg tgacgtctca
    59041 atataatgag actgggggct agcacccatg gcacaaacaa gcgtttcata accttcttca
    59101 aaaactcgtc cttgactgtc tttgagaagc aaggtgtttg agggagcttc gatagctaac
    59161 acttctgctt gaataaaccg gtggttagat tctatttgtg ctgctaggca ggcccttccc
    59221 cacatagcat cagacaggtc ttgaatgtct cctctgaata attggttgat accatttgga
    59281 atataattgg gacagctttc cttatcaatg agaatgattt gggaatctgg attgaggtcc
    59341 ttatatttat caacaaaggc tagaccagca aaggatgccc cgataacatg tatggtcttt
    59401 gtcgttaatg tcataatagt attattatag cagttgtttt taagatatga aagcgtttta
    59461 cctaatccta taaagaaaaa gcaaaggagc tggcctatga tagccaaccc ctttagtgat
    59521 ggttaggaca tgacttggaa aagcaaaact gctaaggccg ctccaataat tggtcctaca
    59581 acaggtatcc aagcataaga ccaatcagaa tctcccttgt tgttgagtgg tagaatagca
    59641 tgaactagac gaggtcctaa atcacgcgct gggttaatgg cgtaacctgt cgttcctcct
    59701 aaggataacc caatcccaat aaccaaggta cctacacaga gggttcctag tcctgctggc
    59761 atatcatata agccaaatgc caaaatacca agcatcaaga caaaggtccc aaagatttca
    59821 ctcaataggt ttgagctggt atctcgaata gcaggacctg tcgcaaatgt ccctaaaata
    59881 tcagcctgac tctcagcagc cagataatgt ggcctgaact gaaggaatac cagagttgaa
    59941 ccaaccatag ctcccaatag ttgggcaagg ctataggcaa tagctgttga ccaagcaatg
    60001 gttccactca tggcaaaagc aaggctaaca gctggattga ggtgggcagg ggcaactttg
    60061 ccactgataa aaactgccac agcaactgca attccccagc cagtcgcaat cacgatccag
    60121 ccagaagcat gggttttcgt tttgggtaag acaacccctg ctaccacacc atttcctagt
    60181 aaaaccaata aggctgtacc caaaaattca ccaaagatat ccatattaac cctcctgctg
    60241 gccttttagg gcactcaaat cattgtctgc aatcacgcga cgaagatcgt cttcttgtgc
    60301 cactctttcc tgatcagacc attcaaaatg tttagccatt tcattaatca ctgggtcaat
    60361 caaagcatct aggctatctc gcataaataa gaggtgattt gttcttctca agaaataatc
    60421 tgtcggttta agagccattt cataatccat cgcataatgt aaggacaagg tttcagctaa
    60481 acttaaccct tcagctgctg ttaattgacg agttaaggca aagacttttg gcgcattaga
    60541 accataaagg tttgccaaat acctagcatc atccatcgaa agaccactaa gtgttcctaa
    60601 ttgagcataa gcttctattt ctgaatctac attggctgga ttgatttcac ctcctgaaac
    60661 aggataggtt tttgaattga taagcttgaa ggatttgcca aactcttctt tgaggatttg
    60721 aataatccct gtcaatgctc cttcagccat tttgcgatag tcggtaatct taccacctgc
    60781 caaggtaaag agtccattct catcacggtc aaaacttgaa cctcgtgaca ctgcagacgg
    60841 atccaattct ttttcagatg tgctggtttc aacctgctta atagcttttt caacagcttc
    60901 tcggctatct tcgtggttaa tataggcttt gacagtatca accaagtgat caaaactatc
    60961 atcactgact ttaccgctgt tgccaccatt gtagtcagaa gcactattac ctgataacaa
    61021 ggggcgaaga ccagcccaac tgctttcaat atcatcaatg gtcacgttgg catttggaaa
    61081 gcggttattg acaacgccta acaaataatc cacatcttct tgagtaactt gtgggtgctc
    61141 caagtctcca gtgtagtccg tgtccgttgt tccaaaataa gttttttctt cacgtggcaa
    61201 gacaaagacc atacgaccat catttaaccc tgtgtcaaca tagacaggtt gagacactgg
    61261 taatttttga cggtccacta ccagatgcac cccttttgta gggcgcattt gatgaatcgg
    61321 ttgtccctta tgagagaatt gacgagtctc atcactccat ggacctgtgg tgttgatgac
    61381 taatttagcc ttgataatga tttcttgatc tgacagcaaa tcacgcgcct tcacaccaat
    61441 aatcttacca ttgtcatcta gcaagaaatc ttctgctttc acatgactag caataagagc
    61501 cccatcacga ttagctcgtt tgatattttc aataacaagc cttgcgtcat tattacggaa
    61561 atcaaggtaa accccaccac caagcaagcc ttcttgtttt aagtctggtt ctcgttttaa
    61621 gacttcttct ttggttaaca ccttgttggc cgctggcgta ttggacacgc ctgctaaaag
    61681 atcatacaaa tccatagcga ccttcaaacg gaacatgcta aaggtactac caggttcgtc
    61741 ataaacaggt aataacatag ggtctggttt tggaatgtgg ggtgcaattt gttgcaccac
    61801 agcccgctct gacaccgtat ctgaaaccac ctccacatca aattgtttca agtaacgaag
    61861 ccccccgtga accaatttgg ttgaacggct agaggttcct tgcgcaaaat cttgcatctc
    61921 aatcagaccc gtatctaggc cactagctgc cgcctgaagt gccacaccag cacccgtaat
    61981 acctccccca ataatcagta ggtctaaatc tctttcttgc attttttgga gagctaagcg
    62041 tcttgtttct cttgaaaatt ccattccatc ctcctctagt tattttgcat cgtcatctgc
    62101 atcttcttct tgggtgaaaa cttgagttgc tttaacagcg cgcttccaac ccttgtataa
    62161 tttttctttg cgcgattcat tcatgctagc cttaaagagc tggcctgtgg catttaactc
    62221 tttcaaagca tccatgtctt cccagtagcc cacagcaagt cctgctaaga aagctgctcc
    62281 tagagctgtt gtttctaaat ttttagcacg ggcaatatca attcctaaaa tatcagcctg
    62341 aaattgcatg agcatattat tcatggctgc accgccatcc acacggagct gttgaatgtc
    62401 aatacctgaa tccacctgca tggtatcaat aacatctcgc acttgatagg cgatagattg
    62461 taaggttgct ttgacaaagt cttctttgct ggtaccacgt gtcaagccaa agacagatcc
    62521 acgcgcatta gaatcccagt aaggagctcc taaaccggta aaggcaggca caacgtagac
    62581 ttcatcatca ctggtagatg ctagtgccag ctgttcagac tctggtgagg tctcaatcat
    62641 tttaagacca tctcgcaacc attgaatggc agagcctgca ataaaaatag agccttctaa
    62701 agcatagtga accttcccat taatcccgta accaatggtg gtcaaaaggt tattactcga
    62761 tagctgcatc tcatcaccag tattcatgat gatgaaagaa ccggttccat aagtattttt
    62821 caccatacca ggctcaaaag ctagttggcc aaacaaagct gcctgttggt cacccgccat
    62881 acctgaaata ggcacttcgc ccccataaaa atgaaaggca gctgttttgc cataaatttc
    62941 agaattggat ttaacctctg gaagcatatc ttttggaata tttaaaagct ctaaaatctc
    63001 atcatcccat gttaagtctt taatattata gagcatggta cgagccgcat tggaataatc
    63061 cgtcacatga acagcaccat ctgtcaattt ccaaaccagc caagtatcaa tggttccaaa
    63121 aagtaactcg cctttttcag ctcgttcttg agcaccagga acatgatcta aaatccaacg
    63181 gatcttggtt gcagaaaagt aggcatcaat aacaaggcct gtcttttcat ggatcatttt
    63241 tgtatggcca tcttgtttga gttgctcagc aattggtgcc gtctgtcgtg attgccacac
    63301 aatagcatta taaataggta cacccgtttt tttgtcccaa accactgtgg tctcacgttg
    63361 gttggtaatt ccgattgctt caatttggct tggtttgatg ctggactcaa taaaagcacc
    63421 cgcaataaca gactgaaccg aattccaaat ctgattagca ttgtgctcta cccaaccagc
    63481 gtgtgggaaa atctgaggga attctttttg gctactgcta accttttccc ctttttgatt
    63541 gaaaataatc gctcgtgaac ttgttgttcc ctgatcaata gccatgatat acttttcttg
    63601 cgacattcat taccctcctt taagtaagcg ttttcctatt tgattctatt atagctaatt
    63661 ttatcagaaa tatattatca agaattttta aagctaaaaa aaagctgata agataggtag
    63721 cttatcccac tagatgatct tgaaaaatcc actgatgaca accacgtctc ctcatttcta
    63781 acgaggtaat ctttcttatc aaagaaaatc aaaagaccca acaatcactc tgctaatcca
    63841 gagtcatcat tgggtcataa agagaactaa gcctcaaagg caacacggta tcaaacagcc
    63901 gcgcctaaga ggcaaagaca attggacaca agagttaagg ctgtcttatt cattacagtt
    63961 cttgattagt cattgattgg ttcagaagat ttttccacaa tatcccctga gttggcgtca
    64021 atggtatagc tgtattcttg atctttgttt tgaaactcga tttcatacac ggctttgcca
    64081 tcttcattat cttgtgtaac tgatagcatt tgagcatcag cttccgtaac agaagcatct
    64141 tttaacgcaa ttgatttggc tttgtcttct gaaagtttaa ctttcttgct agtttgactt
    64201 gtctttggtt gattatccat atgatcgtct ttatcatcca tatcacaggc tgcaagactg
    64261 agtaaagaga ggctggctat ggctagtaga gagaattttt taattgtcat aagtactacc
    64321 ttctttcttt gatttcttct attataactc aaacacatgg tttttcccaa tattttgact
    64381 atacaatata aaaacgtgtg gtcactttga agtatcatac catttaaaat aaaagctaac
    64441 agtcatcacg ataaacaaaa agcagttcag agctgctttt tgtcttatga ttttgggtca
    64501 tctaatgaac ggccgtgcaa gcctttttca cgttgcacct gtcttaattt ttcaggggtc
    64561 acgtcgtttc cttcttcgtc caccaatttg atgccttcga tatggtgtct gacagagcga
    64621 cgatagcctt caatgtattc ttcacggagt tttgcctgtt ccactttttc aggtccagtc
    64681 aagcctaccg tttttttctt tttagccagc tcattgatac gagcaatttt tttaggatcc
    64741 atgttaagcc actaagagcc tgggaaaaaa gtgtaagact taaaaaactg acttgactct
    64801 cactgtgaaa agcaatgttt aaaggccttg ttctttccac tcgggtactg aactcacttt
    64861 tctagctaag tccccaacgg ctctttcctt tctatttact tggtgtttag ttggttaaaa
    64921 gcagcaatgg tcttagcttt gcttactaaa tctgataaaa tagctacacg gttgttctta
    64981 agggcttgat cttctgccat aaccattgta ttatcaaaga aatcattaat cactgggcta
    65041 agggcaaaga cctgttctaa ctgctgggca gcactgcctg ctagagttaa gccttgaata
    65101 gctgcaaaca aagtgttttc ttgctcattt tcaaagaggc tagggtccac ctgaacagaa
    65161 gcgtccgctt tttctgccaa attaaaagca cgtgacaaag attcaactgc tggtttgtaa
    65221 ttttccgtat ggctggcttt gacaagagct tcagctaccg ctaacatttc tggaaccaca
    65281 aaggttgaac ttgctagaat agcttcccga atgtcttttg gtgcggcttt gcccatcatc
    65341 ttatccacac gagcacggat aaagttcatc acatccgcct tattggtata ggtcaaacta
    65401 tcaaaggaca agtcatataa gctatctacc agcttatcca ttgggatgcg ccatccaaaa
    65461 tgatcaagaa tacgaacgat accctgcgtt gcacgacgta gagcataagg atcattagag
    65521 ccagatggaa tcaatccaac agaaaagaat gacaagagag tatccaattt atctgccaag
    65581 gccaggacag cgccaacttt ggtttcaggt agcgcacctc ctgcagcatc aggtaagtag
    65641 tgttcacgga ttgctgttgc cacagcagca tcttcaccag ctagaagagc atatttttca
    65701 cccataatcc cttgcagctc atcaaattca ccaaccatac ctgttaaaag gtcaaatttg
    65761 taaatttggg cagcacggtc aacagctgtg acttcctcag cagataggtt ggcttcctta
    65821 gcaagtgatg cggcaatgac acgcgtacga tccatgtgtt cagcaagaga gccgattttt
    65881 tcatggaagg tcacattggt caatttggca actaaatcag caatttgcaa tttctgatcc
    65941 tcacgccaga agaattcacc atcttctaag cgagctacca aaactttttc gttcccttta
    66001 ataacatttt caatggcttg atcattccca ttacgaactg atacaaagtt tggcatcaag
    66061 tgaccagcct gatcacgtac cacaaaataa cgttggtggt ttttcattga tgttaccaat
    66121 acttcttctg ggacatcaag gtatttagcc tcaaaatttc ccatgaaagc tgttggaaac
    66181 tcgaccaagt tcaaaacttc attaagcaag tcttcgtcaa tgtcaacttg cacaccctgc
    66241 tccacttcaa gcgtcttgat ttgctccaca atcatctctt gacgctcttt agcgtcaaca
    66301 atgacgcatt ggctgcgcaa atcagcctca taagaatcag cacttgtgat agtggtttca
    66361 gtacctaaaa aacggtgacc acggctgacg cgtccagaat gaatatccaa gaagtcaagt
    66421 tccaaggcct catcattcaa cagaactgtc aaggtgtgaa caggacgaat atattcaaaa
    66481 ctattgttag cccagtgcat gctgactggg aaggtcattg ctgacaacac ttcagtaacg
    66541 cctagaagca cttccttagc aggttttcca gcttcgtgtt tggtcacata aacgtattct
    66601 tctcctttga cttcgcggaa ttcgatagca tctgtggtca agcctttgcc acgaacaaat
    66661 ccttgagcag cttttgagaa attcccatca gcatcaaggg caattttctt agcaggccct
    66721 ttaaagtcct cagtcaaatc cgtttgctga tcagctaatc cagacacacg cactgccaaa
    66781 cggcgtggag ttgaaaaggt ttgtatatct tcaaaagaga gacgattttc tgttaagaaa
    66841 gtcgccaagc gctctcccag ttgtttttca cttggtgtga ccacgtaggc tggaagttct
    66901 tccagaccaa gttcgattag tagattttta ctcataatta agataccaag ggcgttaagc
    66961 ggacaccatc aaaatagcaa agcgacgcag gtgcttgcac ctaggaagtc ttggtctttt
    67021 tgacatagtc cgtagcccat gttcagttcc tttctctaaa aagtatcttt ttgattgttc
    67081 ccttaggtag gggggacgca aagtgaaatt atccagtgga taatttcaga aaacaaaagt
    67141 gttccattcc tagttagcca gcctaaagtc tcgccaactc cctcgttcga taagtaacct
    67201 taccgaattg tcactacagc gggagtaacc ttgactcggc gaccttcggt cgcccacttc
    67261 ttgctcgctc ttaagattac aaagctcgca actagatcat ctttaaatcg acttattcgt
    67321 catcttcagc tagcaagatt gcgcgtgttg cttcatccaa cagtggaaat ccaagcttct
    67381 tgcgttctgc aacaaaggtc ttagcaacga cacgtgccaa attacggata cgagcaatgt
    67441 agcctgcgcg ttctgtgacg gaaacagcgc cacgggcatc cagcaggtta aacgtatgag
    67501 aacatttgag cacgtaatca taagctgggt gaaccaaacc ttcttctagg gcacgcgagg
    67561 cttctttttc aaacttttca aagttttcaa gcagcatgtc ttggtctgat atttcgaagg
    67621 aatattttga atgctcatac tcaggttgta agaagatttc accatattta acacctggtg
    67681 cccactcaat atcatagacc gaatccactt cttgaatata ggaagctaag cgctcaagac
    67741 cataagttac ttctgctgtc actggagatg tcgcaaggcc accaacttgt tggaaatacg
    67801 taaattgtgt gatttccatt ccatcaagcc aaacttccca accaagccct gctgatcctg
    67861 ttgatgggtt ttcccagtta tcttcaacaa aacgaatatc atgttctaaa ggattgatgc
    67921 ccaatttttc caaagaagca aggtaaagtt cttgaatatt tgatggtgat ggtttcatga
    67981 ccacttgaaa ttggtggtgt tggtaaagac gatttgggtt ttctccgtaa cggccatctg
    68041 caggacgacg tgatggctct acataagccg cattccatgg ctcaggacct atagcacgta
    68101 agaacgtgta aggactcatg gtcccagctc ctttttcatt gtcataggct tgcatgagca
    68161 tacaaccctg atcattccaa tattgttgta aggtcaagat gatttcttga aaggtaagtt
    68221 ttttagacat ttcgtactcc tttgatagta gtaaaatggt atatcattga caatcgtttt
    68281 tttgtcatca gtaaaatacc tgacgatgtt actagcatgt attacaggtc taggcaccaa
    68341 aaaaccgcat tttgatgctc ctaaatcata agacctaggg gcgtcaaaac gcggttccac
    68401 cctaatttat tacttcattt atatagtatc tttttgggca atattgacaa atatacttaa
    68461 tcacactgcc caaacggaag cgccaatctg cagtcctacc attcggctct aactaccccg
    68521 aactcgcttt agataagata cttgcatcct ttttcctaga gtctagttta gcataaagcc
    68581 attagtttgt ccatcatgag cttaaggttt tgttcgagta ccgtttggaa taatcacttc
    68641 cgctaatagc ttgttttctt ctcgaatacg taaatatatt actacaatgt agcatgggaa
    68701 aagaagcata gccgtaattt tagcatggca aagtaaggct atgcccacca gctcaggggc
    68761 gatatttaaa aagtagttag gatgtttaat cgttttgaac aaccagtgat ccacatattt
    68821 gtggtctttt gctaacatca attttacagt ccaaatgtca cctaagatac gtgtcacttc
    68881 atataaaaca gctactgata ataacatcaa caaaagacct aaaaaactaa tgccatcaaa
    68941 cttaatttgt ttaagcagcg cttcaatcac cgcaaacaca taaatcataa tgtgaagtaa
    69001 cgtcaaaaat ttcgtgttct gagcaccaaa ttcctgtcct ccttgggcta atatggcttt
    69061 ttcatttgtt atcgatttct tcaaaaatac taaacgaata gtaaacatag ctaacatcac
    69121 taaaaagatg gtcacaatac ggctccttat tttcaataat agtttctttc acaaaacact
    69181 aataaagatt atagctaaat gataaacctt tgtcaaaccg ttttcaaaaa agatttagcg
    69241 aattatggct aaatctttgt agttccttaa aaacttgtag tatcagggtt aggaatcgct
    69301 gacattcctg agagatagcg aattgttttt ttatcttctt gtgtcaagct cacatcaaaa
    69361 atagccatat tttccttgat gcgctcatca tgcaccgatt ttggcaaggg aataaaacct
    69421 tctgccagcg accaagctaa ggcaacttgt gccactgttt tgtcatattt attagctaac
    69481 tgctgcatag tctcattatc aaaaatctct ccttgtccta gaggactcca agcttccaat
    69541 aaaatctcat ttgccttaca ataatcaacc acttcctttt gatagcaacc tggggctaat
    69601 cgaatctgat taattgctgg agttatttta gctgtctctt gaagagcttc tagatgatgc
    69661 accataaaat tgctgacgcc aatgctttta ataagccctg cttcaaccgc ctcttccata
    69721 tattgccatg cttgggcatt tgcctctttc caagtgttac gcagagcttt tgggtttggc
    69781 caatggataa gatagagatc cacataatcc agaccaagac ggtcaagaga agcagctaaa
    69841 gcgtcttttg ccccttcata actatgggcg tcattccaga gtttagttgt aataaataag
    69901 tcttctcgta gaaccccaga atccttgatg gcacgaccca cactttcttc atttttataa
    69961 atagctgcag tatcaatatg acgatagcca gccttgatgg ctgctaaggt agattggtaa
    70021 gcttcctcac catcggctgc ttggtaagtt ccaaatccta aaacgggaat ctcatagcca
    70081 cttgtcattt ttactgttgt taccatcaca aaaacctcct tttatcaata tctgtaagcg
    70141 attactttaa tctattctat cataaagaaa gaaaatacaa aaagaattgg cctgccagac
    70201 atagctactc caatcctttt gtatctctta ggcatcaaaa gctttttgcc catttaaata
    70261 ggttgcaaca agtgttaaat ccttatcaag aacaataaag tcagccgcat gcccagcttt
    70321 gatttgacca catacgtcgt caataccgac agaaacagct ggcacataag ttgccatatg
    70381 aatggcttct gccggagttg cgattcccca ggccactaca tttctaaggc cgtcttttaa
    70441 tttcaaaata gatcctgcca agtttccact ctctttaaga cgagcagtgc catttgccac
    70501 aaccacagag aattccccca agaggtaatc accatctggt gaaccacctg ctcgcataca
    70561 gtccgtaatc atggctacat gatcatgccc tttttgctgc atcaaaatat cacaagcaat
    70621 tggtgagaca tggtggccat cacaaatcaa ctctgcgtaa gtatttggaa gattataaac
    70681 cgctcccacc attcctggtt cacggtgggt caatcctcgc atgccattat aagcatgaac
    70741 ccaaacacta gcaccagctt gaacagcttc tttagcctct tgataagtac catttgaatg
    70801 ccctaaggcc actgttacgc cttgttttgt cactgcagac acaaattctt tgacaccctc
    70861 acgctcagga gcaagggcaa tttttttgat gagcccttta gcagcttttt gccaagcatc
    70921 aaattcctcc aagcgtgggg ttttcatata acttgggttt tgagcaccct tatattcttc
    70981 ggtaaaataa ggaccttcaa agtagatacc ttgtatttta gcacctttta cctgatcagc
    71041 aactgaagca atagtccctg atactttttc taactgctca aaggtagaag ttaaggtcgt
    71101 cggtaaaaaa gacgttactc ctgttgctaa tagtccttca ctcatttgat gaatcccttg
    71161 ggcagaatta tccatgacat cagctcccgc atagccatgg atatgcgtat ccacaagacc
    71221 tggtgcaatt tgataaccgg tgtagtcaat gatttgcgca tctgccggaa caatttctgt
    71281 ccactcccca aaaacaccat catgaagacc taggtagcca gccggtttca cctctgttgg
    71341 gtaataaaaa caatctgctt taagatagca tgtcatcttt tttcctccct tttttcctta
    71401 ttatacgcct tattctttac tttgtaaatg gtatatacca ctttttggat tcaaaaaaga
    71461 aaacgtggat gatcattcac gttttctctt ttttaaagct ggtgtgaaag tactttctct
    71521 gctaaattca aggcatgatc tgtgatgcgg gtatagtggg aaataatatc aataaaatta
    71581 atacctgctt gtgccgtaca ttctccacaa ttcaagcgct taatgtgggt tttacgtaat
    71641 cgtcgctctt tttcttcaat ttctttatgg cgagtcacaa tagtttgcgc caagtctgta
    71701 tcactatcaa cgatagctct aatggcatcc agtgttaaac aatgcgtcaa ttgatacatc
    71761 tctgtcaatt cttgacgagc agatattgaa aaaccaattt gtttagatat gatgccttca
    71821 attagaatgc ctaaagactc agaatgatct ccaattcttt ccaaatcacg tgaagagtca
    71881 agaataccag ccaagacttc attttcactt gggctgaggg cttcgttaga aatatcaacc
    71941 aaataagtgg ttaactcctc atcgatggta tcaactgctc tttcataacg cttgaccttt
    72001 tccccaaatt taccgtcagc tgtcataata taactgtaag aagcttcaaa agcttgaatc
    72061 gcataagagg ctaaatgaac caattccttg tgggcatttc ctagtgcgat agaaggggct
    72121 tgggtaataa gtaagcgatc taaataaagg gcttcgtatt tgaccacttc atcttctcct
    72181 ggaatgagtc tagtcacaat catagctagt agactaatga aaggaattaa taagatggta
    72241 ttagtgatat taaaagaacc gtgagaaaaa gcgatagtca tctcaggcgt taaactcaac
    72301 tttgattgta gccataacat caatgatgtg aatgggacta ggataatcat aaaaataatt
    72361 gtaccgatca aattaaataa cacatgagct gctgccacac gtttagcagc aatatttgaa
    72421 cctatagctg ctaagacagc tgtaatgcag gttcctatat ttgagcctaa caaaatagga
    72481 atagctccct gtaaagtcaa aagaccacct gaaaacagac cctgtaaaat cccgataatg
    72541 gctgccgatg actgaatcaa catggtcaaa gccgttccga taaagacacc ttggaagagt
    72601 ttatcaccta atgtcgctaa ataattttga aaggctgaca cagatttcaa aggatccatg
    72661 gcatctccca ttaggttcag cgagaagaaa attcctccga caccaaaaat gatacgccca
    72721 aaattgttga gctttttatt agaggtaaag aaaagacagg ctgcaccaat aaaaatcatg
    72781 ggcaaggcgt aatctcctag tttaaaacca attaaaaacg aagtgatagt cgttccaata
    72841 ttagccccca taacaattcc aatggcttgt cgcaaattta gcaaacccgc agaaaccaaa
    72901 ccaaccgtaa tcacagttac gcctgaactg gactgaatta aggcagacat ggcaattccg
    72961 actaagatac caaaaaaggg attactggtg tatttatcaa tgtaatacct tagtttatct
    73021 cctgctgctt gttgcagacc atctcccata tacttgatac tgaaaagaaa gagacctaag
    73081 cctccaaaga aatgaaatgc aatgtcttgc caatttactg acacaatatt gtcctcgctc
    73141 aattttttag tctattctat tttaatgtat tacggtcttt atcacaaggt ttttttaagc
    73201 gtttctgtgt ataccgatgt caacatttgc atattattgg tttgataagg tgttaggctt
    73261 ttccgatatt ttacatcatt tgtttttgca caaatctttt catttcgttt aattagaggt
    73321 ataatatggc tacgatgaaa caatatcata aaggagattc catgactaaa tcacaaaaag
    73381 aggcgcttta ttggatgttg agtgttctaa ctatcactct aataggtggc tcctgcctta
    73441 tttttggatc ccaccctcaa acgcaagata aggtagctaa acattctaaa agtgctgcta
    73501 gtttactaaa aaaagcagtt aaagcagtta atgacgctga tcgtttagcc actgcagctg
    73561 ctatccaaga agcccagaaa gctgttgata aattagcaga atcttctaag aaaaaaacgc
    73621 tacaagaaca gctaaacgtt gccaaagcaa agcaagagca agaagatgca gctactcaag
    73681 cagttaaagc tgctgaggag actctcaatc aaaatcttaa agatatcgcc caaaaagcag
    73741 ttaacgactt aagtaacaaa ggtaaaaaag ccgctttaca atctcggtta gacgctattt
    73801 taccagcaaa acccattatt gatgaatttc caagacaaag tggagaaata acagataact
    73861 cttactggac acctttccca ggagacgtct cagatactta tgataattcc cagtcaccta
    73921 ctttagaccc aagctcagaa tcttcagctt cagatgttac gccacaacct agtcatcctg
    73981 atccaattcc acctcagacc tcttcagaac cttctgactc aggagacaag caatcatcaa
    74041 aagagtaata caaaaatttt tcgtaaaatc aatcaataaa cgttttagac ggctatctta
    74101 gtgattagtc ttcctgatat cttaaaaaag ctagctcaaa tcaaaagagt ctagcttttt
    74161 gttttgttag atagcattaa atttcgtagc ccattaaaag tcctccgtct tcagcataaa
    74221 agctacacaa acctgaggtc cttccagttt gaatcacagc atcaggatat aaagatttga
    74281 ttttttcact gatctgctca caaatttttg gattttgagc atgagcaatg taaacttttc
    74341 cgcctacata accctctttt tgaatttctt ctatcaaagc agaaactgct tttttttgac
    74401 cacgcgcttt ttgaagaagt tcaagcgttc ctttattgct agctttccca accattctaa
    74461 tattgagtaa gccaattact ttacctacta atttactcag tcgaccattt ttaaccaaat
    74521 tatcaacctt ggcaagcaca aaaatcaaac gtgttttttg ctgataagct gtgatctgtt
    74581 tgacaacttc ttcaaaggat aatccaagat tgatcaaccg ctcaagctcc agtacgagca
    74641 aatccatctc gccacctgct gataaagaat cgattaggtg aatattgaca ttaggatttt
    74701 cttcaagaag ttcattttta gccagtcgtg cactattatg actgccagat aaggtccctg
    74761 taattgtcat cacgataaca ttatctgcac ctctataggc ctgcaaaaag gcttctgggc
    74821 ttggacagct agatgtcgtt gctttagacg actggtacat agttgtcatc atattatcga
    74881 tatctaatcc atcatcatct ctaaaaattt ctgtgccaat ctgtagggtc aaaggcacac
    74941 gttcaaagcg caactctttg gattgtctag tcaaacttct aagatcacat cctgaatctg
    75001 ttacaatttt ccaagtcatt ttttatcctt ctttttctct aatttgtgtt cggtaacaaa
    75061 gaccagatta ttaagccttc gctaagatgt ctaggctaat ggtaataact aatcattaaa
    75121 tcctatgttt tattactagc cttttcaata gttagtaaag tcatccaata gagctataca
    75181 aggaggtaat gaggctcctg ataactaact ttagttgaca aactaagact tttcccataa
    75241 aattatatca ttattaagtc ggtttttgct actgataact catcagaggt aacacttgaa
    75301 aggtatttgt gatgactgat aaagcactct caaaaagatc acttcaaaac ttaacacaat
    75361 ttaataaaga aacacgacgc atagcacgtg aatctatgga aatcgcctta ctgaatcttc
    75421 tagaaacaaa acctttaggt gatattacga tttcagaatt ggtgacgaaa gcaggagtat
    75481 ctcgtaacgc tttttatcgt aattatacct ctaaagaagc cattatagaa caactgttag
    75541 taggggttat ccgtcgtatt tttcgtggac taaaacaatt tgatattaaa actcaggctt
    75601 atcaagcctg gctctatctt tttactgaag ctaaaaaaga agctcagctt cttaaaatga
    75661 ttttcaaaca tcacctgcac catcttctaa cacgattagt cactaaacgt ctgaaagctt
    75721 atcaaaaatt aaaagacaaa aaacaatcgc actataagcg ccttttttgg agcaatgcta
    75781 ttgtttctgt cttgacaaac tggatttcag atgacatgat cgttcctgcc gaagaaatgg
    75841 ctgctatggg cttgcctcta ttaacgtaaa aaggttcctt ttgggaacct tttttatata
    75901 atagttagtc tttttgagct gcaagtgcaa actgacggat agcctgggcc acacccgcca
    75961 tatcattagt caaagtgact ttgtcagcta atggcttgat agctgctgaa gcattttcca
    76021 tagcaactcc taaaccagca taagttaaca tctcaatgtc attgggagca tccccaatag
    76081 ccatcacttg gtcagcagtt aaacccaaat cttctactaa ttctttgaga gccgatgcct
    76141 tgctgactcc ctgagggaga atttctaaaa tattatcttg gctacgaaca acatgaaaac
    76201 tctgactaag ctgatttctc accgcacgtt caaaggcatc tagcgcagct ttttctccta
    76261 agtacatggc ttgaaaaatc aggcgaggag tgtccgacag ctctgctaag gagacaggct
    76321 tgacaatggt aaataccaaa tctccatctt cctgcacaag gtctggcact tcttcttcaa
    76381 gcaccaaata atcgttttcc tcagttaaag tcaggtaaat atctggaaaa ctttggctta
    76441 gctcttccag caattcaata tctgaaacct tcaacatttt tgaatggcgt aattgccagt
    76501 caggactact ataagtacta cagccattat tgataatgag gaattcctct tgtgtcaaac
    76561 ctaattggtc aaaatagggt cttgtccctg actgaggccg gcctgtgcat aagacaattt
    76621 ttaagcctga ctgagctgct tcttggatgg ctgtgatatt ctcttttgga atctgtttgt
    76681 cctggtttaa taaggtgccg tccaaatcaa ttgcaattag ttgaatcatc ctatctttcc
    76741 tctttccatt tgattttagg gaggttccat tttttacggt tgccaatcat gcgtaaagtc
    76801 gtgagtaaaa caaccaaggc ataacattca atcgttgaat ctgctagttt aaaatgcaaa
    76861 acaatagctg caagaataga ccacccagca tagatttcac tacgcaaaac actaggtttt
    76921 cgccctgcca gaatatctct gacaacacca ccgcctgcac cagtcaacac agctgctaca
    76981 atgacagcac ttaaaggctg gttaagacgg acagcatgca aggctccttg gacactaaaa
    77041 gctgccagac caatggcatc agtcaaaaca actgcccgta cccaacctct agctattagc
    77101 ttaggaaaaa gcataatcaa aaccatagca aagaaagcgc aagtgaattc tggcttttgc
    77161 ccccataagg cctctatagg taaaccaatt agggtgtttc gaatggctcc gcctccaaag
    77221 gctgtcacga aacctaaaat aaaaatccct aaaatatcaa attcttcttc catggcaaca
    77281 atagcaccag aaagagcaaa ggcaatggtc ccgatgatat ttaaaatttc ccacatatca
    77341 attgtcataa gctaccctat tgtattttag tcttctttta gtttaccacg ttttccttta
    77401 aaaaataagt agaaaaagat aaaatgtaag gataaaaaag caaggataaa acccattttc
    77461 atccttgcta caaaagattc aaacaattat ccccatactt atcttatcac atcaatgaga
    77521 gctgcttgat aggataaggt tgttttagat tttttccgtc caagggctag ctgtctcttc
    77581 gagtaccctg tttaactcgt caatattttg gaagccttca gtgcatagcc actttcttgc
    77641 ttcgtcctct cctttagtaa tataaactgg aacggatcct gcccacgtgg cacgcccaca
    77701 caaaacaccg ctaaattgag cacctgctgc tgctgcaaag tataatgtct cttgaaaaag
    77761 tttggcagat acgcctgcac tcaaatagat ataagggagg tggctggcag cttcttggtc
    77821 ttgaaaagct ttaatagcct cagcttgact gtaatggact tccccttcag taaaaccttc
    77881 tacataagcc atattaacag gaacctctac ttttagcaca tcaacgccaa aacgcttatc
    77941 cgaaaatact gacatagcac cgttaacctt atgtggctta agctttgcgt atgccgcact
    78001 gttgttatct gatattctct catcataact caaaagttca agaaaaaaag ggatgtcttc
    78061 agctgtacat tctgaaccaa tgcgttcaat ataagcttgt ttttgtaaat tgatttgttc
    78121 atctccatca acatcataat agagcaaaaa tttaatagca tctgcacctg ctgctttcaa
    78181 ccgtttgacc gaccattcca ctaagcaatc gggtaaacgg ctagtggttg tagcatcata
    78241 acctgttttt tcgtaagcta acagtaagcc tgtctgatta gctcttacct tagtagccag
    78301 caacccatat tctggatcta ataaaataga tgaagcataa ggcgtcaatt cctcagaaac
    78361 gagaactttc aatgtttcta tctgtgtaac tgtcgcttct ccttcttgat gtgctgccat
    78421 catttgcttc agtgcacctc gttgatcaaa agctaaagct gatatgattc cttgatggct
    78481 cactttttct aagtaatgtc ttttatttgc tgtgattgtc atgtgatacc tctcttactt
    78541 gaagttgctg atataattgt ttaaaagttg ccatagtcat caaatcttga taatagtgag
    78601 tagctagtct cctaggcaga ctgcctgaga agttaagaca tcaaacggct tagcaatagt
    78661 actcatgtgg ctcaaagaga cttcggcttc gtccacatca ctgtagggac cagcttccaa
    78721 aatttttgtc tgcatgcctt catgtaaaac agcaatacaa tttctcgttt cccctttgat
    78781 tttgaaaaat tggttagaaa tgccctgttc ttgtaactga tgaatgataa agtcacccag
    78841 tttaccacca ctaaatcctg ttgccataac tgaccagctt ttgctaacat tctggtcaca
    78901 tttagctcct tatcaccagc tgtttttgcc gttctgtcaa cacgattaac cgtgtccata
    78961 gccagacaat ctaaaggata ggaaatagcg acagaaggat ttaagataac tgttaaactc
    79021 atctcttctt cctaatcgtg atactcacca cgatcccatt tttccaaaaa ttctgtaaaa
    79081 aaatcaggat cttcttggtt ggcatgatga ctttccaagt gggctatttt agcaattagc
    79141 ttcttattct cttcagtttc tttgtattct gccttgataa aagcatctat aatatcacac
    79201 ataagaagtt caccagtgat tttaccacca aagccaatca cattggcatt caattcttcc
    79261 ttggcataaa gcgctgttgt catatctcga acaagggctg aacgaatacc tggtaccttg
    79321 ttcacggcat tattaatgcc aactccagtt ccacaaatac aaacacccaa gtctgcttga
    79381 ccattaacca cagcttcgcc gacttttttt ccaaaaatag ggtaatgggt tcttgtatgg
    79441 tcataagtgc cacagtcaat aacgtcatag cctttagatt tcaaaaaatc agaaacagcc
    79501 attttttcgt tggtgacaat atggtcacaa ccaatcgcaa ttttcatcac tttatcctcc
    79561 tttaggccat tttattgagc atgtcaacac gaatttgatg acgaccacca tcgtagggac
    79621 cagtcacaaa acctttgacg atattcttcg ctaattctgg acctacaatc tctgccccta
    79681 ttgtgatcat gcgggcattg ttgtgaccgc gcgtcatgta agcagagcgt tcatctgaca
    79741 cttcagcagc aaccattcct tttaattttg tggctaccat aaagggacct gctccgtaag
    79801 catctaccat aatgcctaaa cgaccttctg cttcattaac ggctttcgcc accgctaatg
    79861 tgttatcaat aaaatcactg ttaatatcag tcacgtcaat aatatcatag ccttcttctt
    79921 gaagaaaact tttgatcaat tcttttaatg catttccgtg tgcatctgca cctaaaataa
    79981 tagccatagc ttttcctttt ctaacccaaa acgcttgcca atctagagaa gggggacatg
    80041 attacctgtc cttagatcaa gatgattgcc agtagtctta gtgtcttcca ttatttcttt
    80101 caagacaaag cacttgtgag ttcccacaga gcgccttgcc ttacatgaga aatactcttt
    80161 tcacgttagg gggtaaggca gaaatacctt acgcagttat ctgctattct ccctaatttt
    80221 ttagtcagtc acctgacctg attttatttc attgttttcg catactcagc gttacgtgcc
    80281 ttcatttggt tagcatacca agcaaagaga cctaggtaaa tggccacaaa gatgattagc
    80341 gtgatgattg aggcaatctg acctgttgtc gcttgaccaa tcacataacc aaaaattttt
    80401 tccattggtc cttcaagtgt tgaatgcgta atcaaggaac cagcgcttgt acctgctgga
    80461 aaagccccta cttttttagc caactctgtc gcaaatggag caatcatagt tcctgacaag
    80521 aggaataatg gcaataagag ggaaccaaaa ataatcatgc gaatcaaacg accacgtgtg
    80581 accacaagaa gagctggtgt catccccata gcaataatcc ccgccaatgg taaaatccca
    80641 ttgccaactt ttgataggag aacggcttca atcaacatga ttggggcaag aatattggca
    80701 caggcccaga tttcagcgcg accagcaatg aaaggccagt ccaaaccgat attgaaacga
    80761 cgcccatgca ttctagcatt ggcaaaattg gtaatccctt gtgacaaagg ctcaacagct
    80821 gcgataaacc aagagccaat caaagagaaa agttccaagc aggcaccagc tgtaaatcct
    80881 agaccaaacc aatttttgat agattcaaca gtgaaatgag gatctcccat aatcccaatc
    80941 acaaaaccta gagccattcc gataaagaac ttagagcccc agaagccaat ttttttgttc
    81001 aatttagcag catcaaagtc atatttatct agccccggaa agaccttgtc aaaaatctta
    81061 tctaagacca taatgattgg attcatcatg tagttcatgt gagttgaagt cattggtgat
    81121 tgagaccctg tcccaagaag gtcatcaaag gtcggtttca tcaaatcaga gttaatgatt
    81181 ttcaataccc caacaagaat aactgccaca gtagcaatca aaagagacac aaggactggc
    81241 aaatggttgt gatcagcata ccacataatc aatagacctg tgatagacaa atgccaaata
    81301 tcaaaaatat cgacgtcaag ggtgtccgtt tttttcatga caatcatgac aatattaacc
    81361 accagcatca ccagcaagaa ataaagggta taaggggaac cccaggtaat tgttgcaagc
    81421 ggtgcccaac cgacatcaat aatgtttaaa ctgatccctg tatttttaac aaaggcctgc
    81481 aaagactctg aaaaagcccc cgtcaaaatc ccaataatgg ctccaatacc tgtaagagcg
    81541 atagctaact taatcccgcc ttccagtgcc tttgtgaatt taaccccgaa aatcatggct
    81601 aaacctgtca tgacaatcag catgaccaca cctgatccca actgaatagg aaatcccaga
    81661 atcttgttaa taatgtctaa aaaaggttgc atcatcttgt ctccttatgt ttttattaac
    81721 tcactgcaaa tggttttctt taatcacgcg ctctaattca gcaaaaacag gctcactcat
    81781 gattgggata cgatagagaa tcggtcctgc ttctactgtg ggaattggca tctcaaatcc
    81841 caagtcagtt tttgcaatcg gcgtaaaaat atcataacga gacaccaatt cttctgtgat
    81901 gtctttgacc atcaccgcat cacaatgcac atcatagcca cgatcactca tctgagtttc
    81961 aatcgcatct ttaatttgat ggcttgagtt aacccctgca ccgcaggctg ctagaatttt
    82021 aatcatgctg aaacactcct ttttctatta aatagtttga aatagcttgt ttatcatctt
    82081 ttagactggc tagatagcta agattgcctt tcgtaataaa gaaggtaatg agattggata
    82141 gaatcgtcgt ttgaccctcg ttttgactat tgataataaa gaagaaatcc gttaccaaac
    82201 agtcttcctc tggattaatc atgtgcttaa aggtaagggc ttgactattt ctaacataga
    82261 ccacttgatc aaccaagcaa tacttggttt ctgtatgcgg aatagccgca tacaaaatat
    82321 ctgacccatc tttgaggtcc actttgagtc ctgtcggaaa taccgcctca cgctccacta
    82381 aagcctgatg atactcttgc gtcacatacc caaccttttc caagtagcta gcaacaagat
    82441 caaaaagctc tggctgcgtc cttgcttcag taaatagaat attaggaaac actccctacc
    82501 gcctttctat aagtatcaat ttttaacaac tgtcatctca tcatcaacaa attggtaacc
    82561 gtttacaaaa tcattatagt ataaccttca acataattca acatttttac gcaatatttt
    82621 ttgttctata tgtttgtttt tgttttgttt attttgtttt attgaaatat gaaggtctat
    82681 atgctatgat aaacataagt aaataaacta tagaaaggag ccccttagat gttaaaaaga
    82741 gaaagacttc taaaaattac cgaaatagtc aatgagcaag gtattgttac tgtgaatgat
    82801 attattcaga ctttaaacgt ttctgatatg acagttcgta gagacttaga tgaactggaa
    82861 aaagccggca aattgatccg catccatgga ggtgcacaaa gcattaccat gcctaataaa
    82921 aaagagcggt caaatattga aaaacaaacc gttcaaacaa aggaaaaatg ggaactagct
    82981 tcatatgcga cacaactagt caatgatggt gaaacaatct ttattggtcc aggaacaact
    83041 ttagaatgtt tcgctgagca attaaaaaat cgtcagattc gcattgtgac caatagcctc
    83101 cctgtcttta acatccttca ggacagcgaa accattgacc tgattcttat cggcggtgaa
    83161 taccgatcta ttacaggagc ttttgtaggg tcccttgcca gtcaaaatat ctcatcctta
    83221 aaatttgcca aggcttttat tagctgtaat ggtatttata aaaacgatat tgcaacttat
    83281 agcgaaactg aaggagagat tcaaaagcta gcttttaata attctattga aaaatacctc
    83341 ttggtagata accaaaaatt caatgcctac gacttcttca ttttttacca tttaaacaac
    83401 attgatgctg ttgttacaga ttcgcaaata actgaggacg tcatcgaacg ttatagtcag
    83461 ttcacacaat tattagtagc ccacgaaaac aaggagtaac cgtttcatca agaatggaca
    83521 gcctgtcagc gcatcgtcct taaacacctt ctggcaaaag tgatttgctt ccagagaggt
    83581 gtttttattt tgctcggaac acacctgcta acgtcagagt ctttatgagt gaccacaaaa
    83641 aaagaagccc agattaaaaa actggaacct cttttgagat gaagtaaggc taccaaaata
    83701 acctaagatg attgatgtaa ttcaaatttg gtatccttca aagcacgctt gagtaggaac
    83761 gttaaaggac gtcctgtcac cttagcctgt cctttttcca aatttacctg gaccgattgc
    83821 acaccgggga cagctgataa tttttcagtg accgttcttg cgcaaccgtc acatgtcatt
    83881 cctgtaacct gataatgttt ttccattttg tattctcctt taaatggttt ttccttttaa
    83941 tcgcagggca ttcaaaacaa ctgatactga actaaaactc atggcaaaac ctgctaacat
    84001 cgggttcaat aatgggcctc caaaaagatg aagtaagccc atggccactg gaatcatgag
    84061 gacattgtaa atgaatgccc aaaataaatt ttccttgaca atcctcatag tcgctcgact
    84121 caatgacata gctttcacca aatccagcat atcaggtttc atcagaatca catccgccga
    84181 ttcaatggca atatctgtcc ctgaccccat agctatccca atgtctgcta cagccaatgc
    84241 cggagcatca ttaataccat cacctaccat tgcaactttt ctcccttgag agcggaggtc
    84301 tgctatcacg cctgcttttt gatcaggtaa gacttgactg atcacatctg taatccccac
    84361 ttgagaggca atagccttag cggtagcatc gtggtcacct gttagcatga tggtgtgaat
    84421 tcccagttga tgcaaagctt cgacggtagc ttgactatct tctttgacag cgtcagcaat
    84481 actgaaaaga gctcgtagct gcccctcttt agcataatat acaagggttt ggcctttctc
    84541 agaagcctta gcacaaactg actgaacaca agataaatcg ataccaagaa ttcccattaa
    84601 agcagcattt ccaatcgcca aacgacgccc ttcaagctga ccagtaactc ctaggccggt
    84661 taaagactca aactcttcca ctggtagact atcgtaacca gcttcctgag cagcacgaac
    84721 aatagcctcc cctaaggggt gttgagaata ggcctccaag gaagcagctt cttgcaagat
    84781 aaggtgatca tctcccgaaa aagttaggag cttttgaaga cttggtttcc cctccgtaat
    84841 cgtccccgtt ttatcaaaaa caaccgtatc tacctgatgg gcttgttcta agatgtcacc
    84901 acctttaaaa agaataccat tttcagctgc acgccctgtt ccaaccataa tcgctgtcgg
    84961 cgttgctaaa ccaagcgcac aagggcaagc aatgactaga acagcgatgg ctgttgtcaa
    85021 actaaaacga agactttcct gcatgaatac caaccaaaac acccctgtta acagagctaa
    85081 taccaaaacc accggaacaa agacacctga gaccttatca gcaatagctg caataggtgc
    85141 tttattttct tgagcattct caactagttg gataatttgt gctaacaagg tatcattccc
    85201 aagcttatct ggtttaatcg tgagggcgcc tggcccattc aagctgcccg caaagacatt
    85261 atctttttct cccttttcaa caggcaaact ttccccagtt aaaaaggatt catccaaact
    85321 gctatgtcct tccacgataa taccgtcaat agaaactttt tcacctggtt gaaccaggac
    85381 aaggtcatca tagctaacct cttctaacgg caacaattgc cattggctat ttctccatac
    85441 cctcacaaca gtagccttca aggataagag cttttgaata gcttgggaag tacggccttt
    85501 agaacgactt tcaaaatact ttcctagacc aatgagtgtc aaaatcacta ccaccgattc
    85561 aaaataaagg gagtgcacaa agttggcctg gcccaaactg atttcaacca ctccataaag
    85621 actataagca aaagcaaagc tggttgctaa agctaccaag gagtccatat taggatatcc
    85681 cttaaacaaa gctttaaacc cattatggta ataatgacga tttaatacta agactggaat
    85741 cgtcaagagt agctgactaa agctgtaaac gaaaggatag cgatctggtt gcagaaatgg
    85801 aggaagccat aagcccacca tgtgacccat agctaggtat aatataggaa tggtgaatag
    85861 ggcagaccac aagacctgag accaaataac ctttaggtct tcgtcacgac gacctgtttg
    85921 catgtgtttt gcatgttcat caaagacttg tgcaccataa ccagcagctt ttaccgcttg
    85981 aataactttg gccgtttcta aatcgtcatc ttgataagta accgtgagtt tctcggtcgc
    86041 taaattcaca acagcctgtt ctacttcagg caattgattg accatttttt caattgttag
    86101 agcacaagag gcacaactca ttccctccac taaaaatatc tctttagcca ttaatacgtc
    86161 tcctttttct gacagtggca ctgcccaggc aggcaattac acgacacctc aagaactgca
    86221 ttttcttttt tgacttctag tagctcttgg aatgcctcaa tttcctctaa ggtcatcggt
    86281 aagtcataaa gccgttcaag aagtagatgc gtgtgttgcc gctgacaaat accgtctaaa
    86341 acagtcgcta gtgcttcttt ttgtagcaaa gtctcatcca aaagagcttg ataaatataa
    86401 gctcttcctt gccggtaagt tcccaaagcc tttttttcca ccaaacgccc aatcaaggtt
    86461 ttaatggtag aatctgacca ttgatatttt ttccttaaaa tagtaataat atcactactt
    86521 ttaatatcac cactggccca caccacacgc atgacttccc attcggcagc tgaaatattt
    86581 tgattcatca actcacaacc ttttaatcta catttgtaga tatattatat catatttatc
    86641 tacatttgta aatatataaa gtttctaatg attttatttc ttaagttgac aattttttca
    86701 tttatgatat gattatatga taaaaaaatg ataataataa ggagaactca ttgaaaaaga
    86761 cacttaaaag cactcttatt ttactaggac ttactctagc aataggagct agcactcaag
    86821 ttgatgccag ttctagatct tggaaaagct ggtttataga gaaatacttt tggttaaaag
    86881 gagacaaagg ctattattca gagcaagacg aaactaagtt tgatcaatat gtcaactctg
    86941 ctggagaagc ttcaaataaa ggctttgatc ttaaagaaga acaggtaaat ggcacattag
    87001 tcactaaaac tgttgataat atgcaagttc atacttggaa tgagaacccc agcaataaag
    87061 ccaatcaaaa ggtcattttc tatttacatg ggggctctta cctaaacaac ccaactactt
    87121 atcatatcga catgctaaaa accttatcaa ctagtcttga tgctaagatt atcttaccaa
    87181 tctatccaaa agcacctact tactcttaca gtgatgctat gccaaaattg gttgaccttt
    87241 acagagatac tcttaaagaa acaactgcac aaaatatcac tattatgggt gattcagcag
    87301 gtggtggact agcgcttggt ttagcattag ccctaaaaaa tgaaagttta aaacaaccaa
    87361 aagacattgt tctcttatca ccatggttag atgtaaccat gtcaaatcca gatattgaga
    87421 gctatgaaag taatgatccc attctttcag cttggggcct acgtaaagtt ggggaaattt
    87481 gggcacgccg tgacccaaac aacaccaaac atccatatgt tagtccaatt aatggagatg
    87541 tatcagggct agcacctatt actatgtttg ttggtacaca tgaaattttc tacccagatg
    87601 ttaagaaatt tgatgatata ttaactgcca aaggtcatca acatgaactt atcgtcgctg
    87661 ataaaatgaa tcatgtttac ccaatctatc caattgaaga agccaagact gcacaatatc
    87721 aaatcattga tacgattcaa aaagcttact aaaaacaaaa aacccttaag gtgactctaa
    87781 taagatacct taaaggtttt taatttaatc ttttttatca agctcacgta acagttgatc
    87841 tattttatta ccataggcga tggaattgtc tttttcaaac accaaatctg gaattttgta
    87901 catggtcaat tgtttgccaa gttcacgttt aatcgttcca gtcgcttttt caagccctgt
    87961 ttgtgctttt tgattatcag atgccaagtc actcataata gtgtaataaa ctttagcaag
    88021 tgacaagtca ccctgcattt gcacttctgt aatcgttact ccctgaacgc gtggatcacg
    88081 cacttttttc tgaagaatat catttacttc gcgcttgatt tccatcccaa cgcggtcaat
    88141 acgatgatta gccatagcca tttcctttcc acatttttaa aacaaaagct aggctgaaag
    88201 cccagcttat gacattgcta cctgttttga taacgacaac taaagggaat ctgagaattc
    88261 catgacgaga ctggaaggaa tgccccaagt agctcatctg gtagaacaag tcattatttc
    88321 cgacagagga aaaacgtcac atctcagacc ttcttagccc ctattttctc acaatttctt
    88381 ccataatata ggcttcaata gtatcgtcaa ctttaagatc gttaaagttt tcaatcatca
    88441 acccaccttc ttgagcatta ccgacttctt taacgtcatc tttgtaatgt ttcaagctgg
    88501 ccagtttacc atcaaaaata acgacactat cacggataac acgaacactc gaatcacgtg
    88561 tcaccttacc gttgattacc ataaagccac caattgttcc cactttagaa actttgaagg
    88621 tttcacgaat aatggcttca ccaagaattt tttcttggta aacagggtca agtttccctt
    88681 tcatggcttc ttctacttct tcaatgactt tatagataat gctatgaaga cgaatttcca
    88741 catcatccgt atctgcttgt tgacgagctt gtggggtagg gcgaacgttg aaaccgataa
    88801 taacagcatt tgatgcttca gcaagggtca catcagactc attgatagca cctacagcag
    88861 agtgaacgac attgacacgg acaccttcca cttcaatctt tacaagagat gctgcaaggg
    88921 cttcaacaga accttgaacg tctgctttga tgatgacatt aacagtcttg atttctcctg
    88981 ctttaagggt atcaaagaga ttatcaaggc taacacgctg tgtattttga cgttgtttga
    89041 ggagggcacg ttttgatcgc tcctcaccag ctgcacgcgc agctttttca tcagcgtaaa
    89101 cagcaaagtg atcaccagcc attggtgttt cgttcaaacc agtaatggaa actggtgttg
    89161 atggctccgc agatttaaca cgacgcccaa ggtcatttac catggcacgg acacgaccaa
    89221 aggtattacc aacaacgatt gggtcttgaa catgaagagt tccttgttgg acaagaagcg
    89281 tagcgatagc acctttacct ttatctaagc gtgcttcaat cacagtacca atagcacgaa
    89341 ccgtcggatc agctttcaat tcttctactt cagcaaccaa aaggactgtt tctaatagtt
    89401 catcaatatt tttattaaat ttagcagata tctctacaaa ttcgcactct ccgccccaag
    89461 cagttgagat gataccatat tctgccaatt ctgcgataac acgttctgga ttagcacctg
    89521 gtttatcaat tttgttgata gcaacaataa ttggaacacc agcagctttt gagtgattga
    89581 tcgcttcaat cgtttgtggc ataacaccat catcagctgc aacaatcaaa atggtgatat
    89641 cggtaacgga agctccacgt gcgcgcatgc ttgtaaaggc cgcgtgtccg ggagtatcca
    89701 agaaggtaat tttcttgcca gcttcttcaa tctggtaagc accaatatgc tgagtaattc
    89761 ctccagcttc tcctgttgcc acacgtgagt tacgcaaagt atcaagcaaa gttgtcttac
    89821 cgtggtctac gtgtcccatg atagttacaa caggtgcgcg ttctacaata ttttcaggat
    89881 tgaggtaatt ttcatcctca aagaagcgct cgatatcagc atcatctact tctaccttag
    89941 ccttagcctc aataccataa tctaccatca ataattcgat agtatcccca tctaaagact
    90001 ggttttgagt tgccataaca cccatcataa acagcttttt aacaatttca gcgggttcgc
    90061 gtttgatacg ttttgcgatt tcggcaactg tcatgccttc agtatattca aattcttttg
    90121 gcaattcatg gaatttacgc tcggttactg gttttggagc ggtgttagta ttcttaacat
    90181 ttttgccttt tttggtcttt ttatttttat tccagttact atttttttga tttctcactt
    90241 ggttttgact attccaactc ttcttatttt tcttttgtcc ttcttgtgaa tgatgagtta
    90301 actcacgatt cttttcagga cgtgcttgtt ttttacggcg attatcagca gtagatttag
    90361 cactaatatt tgatgacttt aatttagttt ctgcttcttc aatagatttc agtgctgctt
    90421 cacgatggct catctcctca gcttgtgctt ttaaagccgc ttctttagct tcttgtcttg
    90481 ccaactcagc taaacgctta gcttcttgct gtgcacgaaa acgtgtttca ctttggcgtg
    90541 agtattcagc attttgttca gcttttaagg cagcagcacg agctttgaaa tcaattttag
    90601 gacttttcga ttgaggctct tgtcgtcctt gctttttctg gtttgtgaat cgaccattct
    90661 tgtgattctc cttagcaaag gaacggttac gatcaccaac tagctgatga ttatcatgtc
    90721 taggtgatac attcgatgct tttcgctcaa tacgcttatc gtttgtatca ccttgagaac
    90781 gatgggtaat cctcttatct ccttgttcgt tagtttgatg attattgggc tggcgataac
    90841 ctcctcgacg ttcttgagaa cgatgagaag agccatttgc ttgttttcga gcagcctgtt
    90901 cctttgcacg agcctctctt tcagctttaa aattacgact ctttggctta gagacctgtg
    90961 ttttctctac atgctcagaa cctgtttctt tgaccactgt tacagagggt tgagcaactt
    91021 ctttgggctt gactgtttga gaagctgtca catcaggttt agaagccttt gaaaaacttg
    91081 aaataatctt tttcgcatcc gcttcttcaa cacttgatgc atggcttttc acatctaatc
    91141 ctaagtattt agcgtgttca accacctctt tactactttt accaatttcc ttggcaattt
    91201 catgtaatct tttctttgac aatttgtgtc ctcctattca tctattccat aagagtcctc
    91261 attttctttg aaaatccagc atctgcaacg gcagcaacct tccttggttt acctagtgca
    91321 gcacttaatt ccagtgcatt caacactgtg gagacttcta cattataata attactttta
    91381 tctgtcactt tttttgtcac attaggacca gcatcattgg ctaaaaatac taatattacc
    91441 tgctggtgtt gaatagcttt tactactagt tcttcacctg aaatcacttt tccagcccgt
    91501 tgagctagac caataagact agataatctt tctaaattag tcaagaccta actctcttct
    91561 tttgattttg tgatcaacat aagcaatcaa gtcatcgtaa aaactttctg gaatgtccat
    91621 tgagaaactc ctgttgaaaa cttgtttttt cttggccatt aaggcctctt gattgtctaa
    91681 tttgatataa gcaccacgac cattttgttt accagttgga tcaatgaaaa cttgaccatc
    91741 cttagttttt acaatcctaa gaagatctcg tttagcaata atttcaccag aaacaagtga
    91801 ttttcgtaaa ggtatttttt tgactttaga catcaaacac ctcttttctt acacttcctc
    91861 ggcagtcata acatcgtcaa caactggctc ttccacaact gttgctgctt ctttttccgc
    91921 ctcaagacga tcatattcgc tagctgattt gatatcaata cggtagccag tcaaatgtgc
    91981 cgctaaacga acgttttggc cgcgacgccc gatagctaat gataatttgc tatcaggaac
    92041 tactaccgta gcacgtttaa gatcttcatc gtcaaaaagt accatgtcta cttcagccgg
    92101 agcaatggca ttgtagatga actcagctgg atcatctacc cattgaatca cgtcaatatt
    92161 ttcttcaact ggaatttcaa gccccgtctt agcatctaca cgttttggat ggaacttgct
    92221 gatgaccttt ttaatattac ttccaccacg tccaacaatt gttccgatgg catcaacgtt
    92281 aggattatga ctgcgcacag caaccttggt acggtcacct gcttcacgag agacactcat
    92341 gatttcaaca gtaccatcaa agacttcagg aatttcttgc tccataatac gtttgatgaa
    92401 ttctggatgg ctacgactaa caaagacgtt aactccttta ggattatttt caactttgta
    92461 gacataaacg tcaatacggt catgtgattt gaaagtttca cctggaatct ggtcttggtg
    92521 agacaattgt gcttctaagg aaccaagatt gacataaata aaacgttgat caaaccgttc
    92581 aactgttcct gtcataattt caccttcatg ctctttgtat tcattgaaca tcacttcacg
    92641 catttggcgg cgcatctttt ccataatagt ctgcttagct gattgagctg cgacacgtcc
    92701 aaattcattg acagattcct caaagcgaat cttatcaccc aattcatagg cagaactgat
    92761 agcaagagca tctttcaaac taatctcaag ccggctgtca aaaacttctt caacaacctc
    92821 acgaaccgtg aatacttgaa aatcagctgt tttttcatta aattcaataa cacatgattc
    92881 tgattgacca tagcgacgtt tataggcaga ctttaatgat tctgtcactg cgtcaataat
    92941 atctgcttta tcaatgtgtt tttcttcttc caaaatacgg aaggcttcta gcatttcttt
    93001 gctcataatg ttatctacct tgcttgtaaa gcttggcaaa aatcctttct taaattaata
    93061 cgatcaatag ccccctaaag gctcccttaa ttccttttgt ttagcttgta taaactctat
    93121 aggtgttgtt tcaaatttgc ttaagcgttc ctaaaaaagt ttagtgcttt gaaataaaag
    93181 ttataatttg acagccattc tcaccttagc aactgcttga tatggtatat tcacgatctt
    93241 atgacgtgtt ttatcaagat aatcaatggt caacgtttca ccatcaaagg ctagtaagtc
    93301 tccttgaaaa actttcacct tatcaatagc ttgataaaga ctcacattga tataagagcc
    93361 aactgctgct tttaaactgt cagctgtctt aagcggacgc tccaaacctg gactagagac
    93421 ttctagcata tattggtttg gaaaaggatc tggatcaatc gtatctaaca gcggactaat
    93481 aatattcgtc aagtcagatg tatcttccac tgtgattcca ccttccttat cgactaaaat
    93541 actaaggatg tagtcactac ccattttgtc atattcaacg tctactaatt cataaggtgc
    93601 cttaatctca ggtgttactg tcttggttac gatatcgata atagatgtat ttgctatttt
    93661 gattacctcc tctattttta tgctcttctc taagataatt ggtccttggg aatccactta
    93721 atacaaaagc ggcgagacat atcccaccac ctttctgtat tatttaagcc cattatacca
    93781 taatttaaga ggaatgcaag gatatgcact ttgttttact cacaaggaga ggaggggatt
    93841 cgaacccccg agccccgtta aggactacac gctttccaag cgtgcgcact aagccactat
    93901 gcgacctctc cattactaaa gaagttaata ctgtatcaac tcctttatgt tatcatattt
    93961 tgaaacaaaa tactactaga aatttgcctc aactcggtaa atgacttgac ctttattaga
    94021 gaacttctct tcatattctg tcatgacatt tccttcatag ttactagcgt gtaagtcaag
    94081 ccagatctgt ctcaaggtca tgccgtattg agaaaaacta gctaaactgt actcaaacaa
    94141 gccccgatta tcggttttaa aatgaatttc accgtgttct ggcaagatac gcttgtaagt
    94201 gtctaagaaa tccttgtagg tcaaacgacg tttttcatgc ttggtttttg gccaaggatc
    94261 tgaaaagttg agatacatca tatccacctc accatcttca aaatagttgg ttaaacttga
    94321 tccatccact cgcagaagtt tgacattggg tacttctgaa gctaatacct tatccaaggc
    94381 gtagcttagg acagataatt gaatatcaat gccaatgtag ttaatatcag gatttttcaa
    94441 ggccatccct gtgataaatc cgccctttcc tgaaccaact tcgatatgaa taggacggtc
    94501 atttccaaaa acgtcatgcc aacggccctt ggcatcttct ggatttaata tcacatagtg
    94561 tgggttatta gctaagtgct cctcagcacc ttttcgtttt ctaactcgca ttatttcttt
    94621 ctaaatattt ctctaaattt tctgagggca taaatctcct gattcacatg ctccatgtca
    94681 cgcttgtcaa aacacttgag aatttgtgtc aggtgagaaa attgaccata ccaaataatt
    94741 ttttgcataa ccttgtcatt atttttatag ccataataag acagccattc tgaccaacga
    94801 gaccgtggaa tatagtggct caacaggtaa gcaacatcat acatccgatc agtcagacga
    94861 acagaatccc aatctactaa aaaaatcata ccactagtag taatcaccca attgctatgt
    94921 ttaatatctc catgcacaat cgttgctact tctgatttga actctggtaa gctccgtttt
    94981 aattctttaa cgatagcttg taagtatgaa ttttgctgaa tttgcaaggg tgcattttgc
    95041 tcaaaatcaa ccaataaatc gtatgggttt tcaatcttat aattgagctg aagcagttga
    95101 ttgactaatt ttttagattt gtgaaggcgc aatagaatat gaatgatttg cttactgttc
    95161 atatcttctt tggtcaatgt acggccgtta agccattctt gggcactcat catatcacca
    95221 ttgcccatgc gtttggccca aagtaactgt ggcgcaatct gttcttttgc taaggcaggt
    95281 agaatagggg tcgtatttaa ttttataaag acacattccc catttggata agtgccttta
    95341 taagctttgc cacttttccc acgtaaggga gtcaaggtaa gttcttgttc cgtcgttgtc
    95401 accttatcgc cctccttttc tatcttttat agtcgtttac ccctatttta cttgttttag
    95461 gctacttagt caatgatctt ctttaactta taaggtagat atatacaagc tatgaaaacc
    95521 atacctacaa tcaaaatgag tgcttttggc gctgatgagc aacacagcat attgacgatt
    95581 aacattaaaa agcttaaacc tcgtaaaaaa cttaacacat ttttcttctt gctccgacta
    95641 ttttcaggat aaagactagt catataatgg taatcgtagt gataataaag tgaaagtaat
    95701 tggaatacaa ctaaatagtt aaaaatgagt gctaaactta ctgacaaata aagattatgg
    95761 ataaaaaata cagataatga gcttaatagc attagtcgta aaaataagcc caaataatct
    95821 gaactacgta aaaaggctct agcataaagg gatagccaaa ggtttgaagg agtttgctta
    95881 actaatttta aaagaggatt tagataagtt ctttctttca cttttgtaga aattcctttg
    95941 actgttgtaa aaagagaata aaactttaaa atactttgct tgcgattgct ttcaaatgcg
    96001 acagcttttg cccaatctaa acgatttcct ctcaaaaaat atcttgtctt tcgactaagc
    96061 actactcttt ttagtgccaa taatatcaaa actaagataa taaaaataaa taaagacaga
    96121 cctagacgtc taaaaatagg atataaaaag agcaatatag cagtctgcaa agttccccaa
    96181 agcaaaaaag aaagtcgttc agcttgtttg atataagaaa tcacttcttc ttcttttgga
    96241 agtaagaaat gctgatctgc ctcttctaga tacgttgcta tagatcccat actgagcaat
    96301 aatgggatca atatcccaag acaaacctga ataggtagat gattcgttgg aaaatggttt
    96361 agtagctgac catactgcac catagcatag cctaataaaa acatcaacac caaaacaaag
    96421 tgatcattta agacgtaacg aaggtatttg ttttgttgtt tttgaaagtc ttgacggcgt
    96481 ttcagaaata atgctttcat acttaatcct cttttgttaa tgcaagatag atatcattta
    96541 agctcgctga acggtcacca aaagcttctt gcaagtcagc aagagttcct tgggcacgaa
    96601 cttgtccatg atgcaaaatc acaaagcgat cacacattct ttcagcagag tccaaaacat
    96661 gtgtactcat caaaatagat tttccttttg ctttttcgac ttctagcgtt tggattaagt
    96721 ctgaaatagc taaagggtct aaccctaaga atggttcatc aagaataaat agacttggat
    96781 caatgacaaa ggcacaaata atcatgactt tttgtttcat ccctttagaa aaattgacag
    96841 gaaaccattc aagtttgtca gttaaacgaa acatttccaa gaaaggttgt gctcgttttt
    96901 gtgccacttc taagtcgata tcataagcca tagctacggt gttgatatgc tctgataagg
    96961 tcaattcttc atagagacta ggagtttctg ggataaaacc tattttttga cggtaggcaa
    97021 ctgcattttc tgctagagtt aaaccatcaa tagaaatact tccttgataa ggcttcaaaa
    97081 agccaataat ttcgttgata gttgttgact ttccagcacc atttagcccg atcaaaccga
    97141 ctaactctcc attatctaca gaaaatgaga catcgtttaa aacagggata ttgtgatatc
    97201 ctcctgttag atttttaatg tttaacatat aatttctttc tagtttttga tatacttata
    97261 atatattata acaaattcaa gtagagaagg tgatataaaa tggaaaattg tattttttgc
    97321 agcatcattc aaggggatat cccctcttcg aaagtctacg aagatgagca ggtcctcgcc
    97381 tttttagata tctcacaaac tacaaaaggg catactctag tcattcctaa gcaacatgtt
    97441 cgtaacttac tagagatgac tgctgagaca gctagtcatc tctttgctcg tattcctaaa
    97501 attgctcgtg ctatccagtt agctactggc gctactgcca tgaatatcat taacaataac
    97561 gaagccttag cgggacaaac tgttttccat gctcatgttc atctcgttcc tcgttataat
    97621 gaaaaagacg gtatctcaat tcaatacacc actcatgagc ctaactttcc tgtcttggaa
    97681 aagctcgccc gacaaatcaa tcaggaggtt agttcatgaa agttaaaacc gtgatagccg
    97741 tcggattatt atcttttacc gcttacaaag catatcaaaa acgttgtacc ataaaagagc
    97801 tgttatccat cagtcgacaa gcaaaagatg ctgcccaact tgatttagat aacattaaag
    97861 caaaccttga cctcattcac agtcaaggaa aagtaattca aaatattagt caggacttgg
    97921 cccataaatg gcgctacttt aaccaagaga cacaagcaca ccttactgaa atccaaaatc
    97981 gtatggccaa atatcaagaa gatagtgagc taatttctag tgaatcacct acttgccaaa
    98041 ccgtcatttt aactaacaac cattccagat agtattatct ccctcatata ctttatttga
    98101 aatcacagac agctatcatc tttgatacct gtctttttta tattcaaaat cggatatttt
    98161 aaacataaaa accctcagaa cgttaggtct gagggttgat attagcagga ggaactaatg
    98221 atccagaccc tgatgagcta gactcatcag ctgctaaagc atctgatgaa gaagacggcg
    98281 tagttggcgt atggcttgaa gcagtagagt cctggtctgt actagcactc tgataagatg
    98341 agccagtatc tactccactt gaataattag cgtaagagct atgactatca gaataagatg
    98401 gagcctggcc tgaagagtca tagttgttgt ttactgtctg agacttagtt gacccataca
    98461 aattttcata aacagtagca tttgttttta attgactaac cttatgaagt cctaattctg
    98521 ttcggatacg attttggatt tctaacaaat gattagaggt aacaatttgg tatgatccac
    98581 catctgataa agtggcatct tctcctttta gttgataagt tttaatagtt ctaagtgcgt
    98641 cacgataacc taatagacta gggatagtgc gagaagagat ttcgatattc gtttgcatat
    98701 tactacttac agcagataaa atcttccgat aagagctaat gctatcaaga gcaaggattt
    98761 ttttcaatac cttttgaatg acttcacgtt gacgcttttg tcgaccataa tctccctcag
    98821 gatcatcata acgcatacga gcataaacca aagcttgttc accgttaatt ttgtgtgttc
    98881 caggcgcaac agtagcttga tattcaggtt cgttttcagc aatcgagata ggaaaatcaa
    98941 actcatttgt aactgtaatc cctccaactg cattcacaag atcaataagg ccttgcatat
    99001 taatttgaac atagttatca atggtgatat tcaaaagatc ttgcacggtc ataatagcca
    99061 tctgagcgcc acctgctgca taagcagcgt taagcttagc ttcaacacca ttcatttcat
    99121 tatttttggg tccagataac gtggttaagg tatctcgttc taaactagtc atagttgttt
    99181 tcttggtctt tggattaacc gtaaccaaaa tcatcgaatc actgtttcct tcccacttgg
    99241 aggcacgctc tgaagagcct gtatcaacac ccatcaacaa gatagaaaaa gctcttgttt
    99301 gtttaatggc atcacttttc tttgaagatg tcgaaaaatc tttaaaggtc tttgataatt
    99361 ctcctgttga gaaggtataa gcactagtta gatagacacc taatgccaag acagttgtta
    99421 acacaatagc tgtgaacatt aaaactattt tttttccaat tttcatcgat tcacttactg
    99481 acttacagat ttacgcatat gataaacatc taagtcatct ccattttttg atttgatgtc
    99541 gttttttcgc atactttcaa tacgaaaacc atacttttta tacaggtaaa tagccttagt
    99601 atttcttact tgaacgtcca acttaaggct ttcgatataa gggttttctt cagcccaatc
    99661 aagagcaatc tctaacaata attgaccgat accataacca cggtaagtct tagcaactaa
    99721 cataaataca tctgcttcaa cttggccttg ggataatact tccccagaaa gatttaaaag
    99781 ccctactact ttttcatcta atctagctag caggcaaaaa tcaataaaag aggtttgact
    99841 tcttgataaa aagtctgata attcatgagg agtagcctct aatatagtct ctacgcctgt
    99901 tataaaatct gtttctttgg cagctgccgc cactaaggaa agtacagctt ttgcatcttg
    99961 aggtacgcct tcttcaataa cgagactttg ctgaatcatg tgacattatc tccagaagct
   100021 gacgagagcg ctcaccatgc gctaacaagt ctagttgacg acctttatct cgtttagtaa
   100081 tggttatttg caaatagtct tgtaataatc cctctcctaa taattctccc cactcaataa
   100141 cggtaacacc attaccaaaa agaaaatcat ctaaatcaat agagtctgga tcatcaccaa
   100201 cacggtaaat atctaagtga taaagaggta gacgtccttc atattctcta acaatagtat
   100261 aagttgggct tttgatcatt tgactaatcc ccatcccttt agcaatacct tttgccaatg
   100321 ttgttttacc ggcacctaag tcgccagaca atacaatcac atctccaata gacaaataag
   100381 tacctagggt ttctccgtaa gctttaagag tatattcatt ttcactataa aacatagcaa
   100441 cattatatca gaaaaaaaac atacttccaa gcactaccta gaagatgact ccaataaggt
   100501 attcgtaaag taaaaacgct tcgttatatt aaaggttaaa atcaattaaa gaagcggcag
   100561 ttagtagcaa aataagtaaa ttatttggtt ataagatagt taatatgatg aaatttacaa
   100621 tgaacaagaa ggttgctccc caaataatag ggtgaatatc ttttgttttt ccctcaacaa
   100681 cttttactag acaatagaaa ataaaggcag cggcaatacc ataggaaata gagtaacaca
   100741 gcgccataaa gaaagctgca aaaaaagctg gaagagcatc tgcaaattta ctccaattaa
   100801 catcaagaaa agaagacacc atcatgacac ccacaacaat taaagctgga gccgtagcag
   100861 cagctgggac aatacctaca agcggtaata gcaatattga taataagaag catactgcgg
   100921 tggagactgc tgttagtcca gtacgtccac cttcagcaat tcctgctgct gattcaacat
   100981 aggtagtcgt atttgaagtt ccaaccaaag ccccaataga agtaccgata gcatctgcaa
   101041 aaagcgcacg atccattttt gaactaaagc ctatactatt ttccaaagca ttctcatcgt
   101101 cttgagagaa aatacctgtt cgacgaccag ttccgataaa ggtaccaatt gtgtcaaaag
   101161 tatctgatag actaaaagca aaaatagtca tgaaaactag cggtaaacga cttgaatcgc
   101221 taaaaagaga actcaaacca tcgaaagctg caaggaaagt tgtacctaat tcagtccaag
   101281 cttcaccaat atggctgatc ccaaaattga ggttggacac atccactatt cctaaaggaa
   101341 tacctacaag agttgttgcg acaataccaa ttaaaatagc acctctaaaa tttcgaatca
   101401 caagagctgt cgttaaaagt aaaccaaaaa tagcaagtaa tacactagaa tccgtaaaac
   101461 tagaaatcgt aggtacaact ccaccattgg cgtctacaaa taatagacca tctgcaaatg
   101521 ttttagccga tgctttagcc ggttcaacac catttaccat tactatattt tcagcagaga
   101581 tagaaaaagt aatgatattt gcgtttttaa atcctaaata agctacaaag acaccaattc
   101641 ccccaccaat agcatgctgt aaactaactg gaatcgcctt gatgatactt ttacgaaact
   101701 tggttacggt aataaaaata ttgaataatc cacaaatgaa aaccattgcc aaggcttctt
   101761 gccatgaaaa ccctaaagca aaaacaactg tataagtgaa aaaagcgtta agtcccattc
   101821 ctggtgccaa cgcataaggc acattggcaa atagtcccat aattaaggtt gatatggctg
   101881 ctgcgataat cgtagccaaa aagacagcat tagagggcat ccccgctgca cctaaaatac
   101941 ttgggttaac aaacaaaata taggacatgg caaaaaaggt cgttaaacca gccataatct
   102001 cagttgagac agttgtccca ttttcgctta acttaaaaaa cttttccatt gaaatggagt
   102061 ctccttaatt aaatagtagg taaaatcaaa aagcgcttat cactagataa gtctttttga
   102121 cacctcatta ttattgttat tgttcgtatt aaaatgaaca ataacactat gttaccattt
   102181 ttttgttcac ttttcaacgt ctgtaacttc atttattcat taaaaaaaca gttatcctat
   102241 cttttttact aatgaatacg cttaacttat cttttctctt tatcttggag caaaatttgc
   102301 tataatttaa ttatgactaa aaaattgatt gccattgatt tggatggaac cttattacat
   102361 catgacaaca ccatctctac ccatactcaa aaaatcatca aagctgtcca agacaagggc
   102421 caccacgtca ttatttcaac aggccgtcct taccgcatgg cactggacta ctatctgcag
   102481 ctcaatttaa agaccccaat cattactttt aatggggcct tgacccacat gcctgaacaa
   102541 aaatgggcct atgaacataa tgtcactttg gacaaaggct acctactaag gttactaaaa
   102601 tatcaggatg atttccagat ggattttatt gccagtgagt atcgaaaaaa tgtctacatc
   102661 accatgacca atccagaaag tatcgaccct caactctttg gtgttgatga aattactcag
   102721 gacatggcat tagagattac caaaatcact cgaaatccaa acgccttatt gatgcaaacg
   102781 catcacgaag acaagtatgc cttagctaaa aacatgcgtg ctttcttcaa agatgaaatt
   102841 gaaattgatt cttggggagg ccctctcaac attcttgaaa tttcgtctaa gaatgtcaat
   102901 aaagcttacg ctctgaacta tctccttgga atttacaata tggataaaaa ggatttaatc
   102961 gcctttggtg atgaacacaa tgacactgag atgctagctt ttgctggaac tggttatgct
   103021 atgaaaaatg ctagccctgt gctactgcct tatgctgatc agcagcttaa tttttccaac
   103081 gaagaagacg gtgttgccaa aaaattggaa gaacttttct tgtagtagca aacgaaacca
   103141 ctatttttca gaaaatggtg gtttttcttc tgtcaacagc tatcaaaaaa tgaaaatcat
   103201 tttaataatt tcaacatttt tcagcatatt tttgttttaa acagcttgaa aacaccttta
   103261 a
//
LOCUS       DATWVB010000003        82721 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.003, whole genome shotgun sequence.
ACCESSION   DATWVB010000003 DATWVB010000000
VERSION     DATWVB010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 82721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82721
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.003"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            276..1835
                     /locus_tag="VCX65_000211"
     CDS             276..1835
                     /locus_tag="VCX65_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEP5052708.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSDAFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTCFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMGNVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKASHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLSTNYKVDKQI
                     TTKSFIVYQKK"
     gene            1932..4130
                     /gene="nrdD"
                     /locus_tag="VCX65_000212"
     CDS             1932..4130
                     /gene="nrdD"
                     /locus_tag="VCX65_000212"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEP5052709.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIIKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            4312..4458
                     /locus_tag="VCX65_000213"
     CDS             4312..4458
                     /locus_tag="VCX65_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052710.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSKKKTDKKSRVQELKARFLEKSK
                     KQDN"
     gene            4487..5422
                     /locus_tag="VCX65_000214"
     CDS             4487..5422
                     /locus_tag="VCX65_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEP5052711.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKASLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENQTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLSEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIADSQLSYGELTVELPKD"
     gene            5431..5940
                     /locus_tag="VCX65_000215"
     CDS             5431..5940
                     /locus_tag="VCX65_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP5052712.1"
                     /translation="MEIRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLSSQGVPAIQYVAFDERSQAIGFLNLRLRLNERLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSYAISKNITTILVTCDETNVASRAVIVANGGVLEDSRGGTERY
                     WIEEQRGDK"
     gene            5940..6554
                     /gene="nrdG"
                     /locus_tag="VCX65_000216"
     CDS             5940..6554
                     /gene="nrdG"
                     /locus_tag="VCX65_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEP5052713.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRRELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(6728..7459)
                     /gene="yaaA"
                     /locus_tag="VCX65_000217"
     CDS             complement(6728..7459)
                     /gene="yaaA"
                     /locus_tag="VCX65_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEP5052714.1"
                     /translation="MLTFLIPTAKEMMIPKESHPHLLPQDSQAILKIMAAMTTEDLAK
                     SYRIKEEAAKKEQQRWQDMASQQNLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHPDLSTDHEFVYIKKEA"
     gene            complement(7501..8358)
                     /locus_tag="VCX65_000218"
     CDS             complement(7501..8358)
                     /locus_tag="VCX65_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEP5052715.1"
                     /translation="MTYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPANKAYGLYHTSFLVPDRHSLGLVLNHFLTRGISLEGSAD
                     HGYSEAIYLSGPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSILEQLTDIPKR
                     FLLAQDTRIGHVHLSVKNALASSLLYQKVFDLGDKMTIPSASWIASGNYHHHLAFNHW
                     SAPYLKKHQEGAPGLAFLTIHIETPLLFSATLKKARLHGLAILQEDSSSFTTEDEEGI
                     CVNVILGQD"
     gene            8545..8882
                     /locus_tag="VCX65_000219"
                     /pseudo
     CDS             8545..8882
                     /locus_tag="VCX65_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018307.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(9161..9874)
                     /gene="treR"
                     /locus_tag="VCX65_000220"
     CDS             complement(9161..9874)
                     /gene="treR"
                     /locus_tag="VCX65_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEP5052716.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            10085..12109
                     /gene="treP"
                     /locus_tag="VCX65_000221"
     CDS             10085..12109
                     /gene="treP"
                     /locus_tag="VCX65_000221"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEP5052717.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQNAL
                     QQVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGTVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANSIG
                     VGGLPGFMAINVKYMIPFFICMVVAIVVPMFLAFFFRKSHIMTKTEDEAKLPETPVSD
                     APVATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDAFTVTVEGSLPRQIKANDKLAVAMKK"
     gene            12177..13805
                     /gene="treC"
                     /locus_tag="VCX65_000222"
     CDS             12177..13805
                     /gene="treC"
                     /locus_tag="VCX65_000222"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEP5052718.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFEDLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAE
                     EAFAIIKAKSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYAGEVELELPPR
                     YQHGQALISNYEKVSICEKVMLKPYQTLAILADN"
     gene            14013..15908
                     /gene="pepO"
                     /locus_tag="VCX65_000223"
     CDS             14013..15908
                     /gene="pepO"
                     /locus_tag="VCX65_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEP5052719.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGDHIPDDAILKNFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNKKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDESLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(16074..17114)
                     /locus_tag="VCX65_000224"
     CDS             complement(16074..17114)
                     /locus_tag="VCX65_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEP5052720.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(17248..18015)
                     /gene="rpsB"
                     /locus_tag="VCX65_000225"
     CDS             complement(17248..18015)
                     /gene="rpsB"
                     /locus_tag="VCX65_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEP5052721.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADIQADSIEEIVEVVEGDNA"
     gene            18319..21393
                     /locus_tag="VCX65_000226"
     CDS             18319..21393
                     /locus_tag="VCX65_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEP5052722.1"
                     /translation="MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLKKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDEIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPVATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
                     EPFNRQESLAYINSQLGSQPVTEEEMEHLYQASQGNPFFLSEYTQTLLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMEE
                     QFDRIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKNIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQFEKAVAY
                     QKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLQIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLVFYLMAVVKYQLIFQGA
                     TLSQQEKEMADYLLSESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(21424..22410)
                     /locus_tag="VCX65_000227"
     CDS             complement(21424..22410)
                     /locus_tag="VCX65_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HEP5052723.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPN
                     LAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHN"
     gene            complement(22596..24137)
                     /gene="hutH"
                     /locus_tag="VCX65_000228"
     CDS             complement(22596..24137)
                     /gene="hutH"
                     /locus_tag="VCX65_000228"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HEP5052724.1"
                     /translation="MTRVINLDGESLTIEDVIAIARQGVACRIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKRVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAIGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLIEGSQNTTVATQSRV
                     QDPYTLRCMPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KPENHELGKGTKVAYDLFRKEINFIEHDKHIEIYDELNKASAVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(24148..25491)
                     /locus_tag="VCX65_000229"
     CDS             complement(24148..25491)
                     /locus_tag="VCX65_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEP5052725.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRAPEKNVPRALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFENLAKLSVVFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI"
     gene            complement(25711..26307)
                     /locus_tag="VCX65_000230"
     CDS             complement(25711..26307)
                     /locus_tag="VCX65_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HEP5052726.1"
                     /translation="MTKVTIKAPSDYLQTDWSGGETNQLFLYPEDGDYKKREFSYRLS
                     KSTVALRQTTFTLLDGYHRILMTLDKPITLSDLSHAKEISLTPFEPYAFEGDTRIVSR
                     GICQDINLMYDDQYQGQLLPVWSDTPFEAPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVIEQEASLSDLKVCPNQTSPAQTPVAVWAGLWYKT"
     gene            complement(26329..28002)
                     /locus_tag="VCX65_000231"
     CDS             complement(26329..28002)
                     /locus_tag="VCX65_000231"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEP5052727.1"
                     /translation="MVLSDIEIANSVTMEPISKVANQLGIDEEALCLYGKYKAKIDAR
                     QLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKA
                     RLEKIIIGYNYQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKANLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVALAEQDNQFCFVYEEDDSIETKLT
                     KIVTKVYGGKGIRLTPAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFT
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(28020..28646)
                     /locus_tag="VCX65_000232"
     CDS             complement(28020..28646)
                     /locus_tag="VCX65_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HEP5052728.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQAIITEIHAKSTALQASLLAAIDKDTEAFNLVSAVFDMPKETDEDKA
                     ARRTAMQKALKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     SAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(28657..29556)
                     /gene="ftcD"
                     /locus_tag="VCX65_000233"
     CDS             complement(28657..29556)
                     /gene="ftcD"
                     /locus_tag="VCX65_000233"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HEP5052729.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRELDIPIFLYEDSATRPERQNLAKIRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEVIGLAPAKALIDV
                     AEYYLQVEDFDYPKQVLENHLLG"
     gene            complement(29644..31674)
                     /locus_tag="VCX65_000234"
     CDS             complement(29644..31674)
                     /locus_tag="VCX65_000234"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HEP5052730.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRWRPKDRIYGKPINEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFQSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAI
                     IAEVDQSRIETRHSQGWVTQIAESPEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGKHEDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTVALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH"
     gene            31966..33231
                     /locus_tag="VCX65_000235"
     CDS             31966..33231
                     /locus_tag="VCX65_000235"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HEP5052731.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYPFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(33289..34821)
                     /gene="ahpF"
                     /locus_tag="VCX65_000236"
     CDS             complement(33289..34821)
                     /gene="ahpF"
                     /locus_tag="VCX65_000236"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEP5052732.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHGSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTNNMTIIKNVATKDIVGEDHVTGLSYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(34842..35402)
                     /gene="ahpC"
                     /locus_tag="VCX65_000237"
     CDS             complement(34842..35402)
                     /gene="ahpC"
                     /locus_tag="VCX65_000237"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEP5052733.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            35809..35879
                     /locus_tag="VCX65_000238"
     tRNA            35809..35879
                     /locus_tag="VCX65_000238"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35841..35843,aa:Cys,seq:gca)
     gene            36398..36601
                     /locus_tag="VCX65_000239"
     CDS             36398..36601
                     /locus_tag="VCX65_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEP5052734.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            36797..37258
                     /locus_tag="VCX65_000240"
     CDS             36797..37258
                     /locus_tag="VCX65_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEP5052735.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            37258..39702
                     /locus_tag="VCX65_000241"
     CDS             37258..39702
                     /locus_tag="VCX65_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEP5052736.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSYGKLTFHIA"
     gene            39880..40170
                     /gene="groES"
                     /locus_tag="VCX65_000242"
     CDS             39880..40170
                     /gene="groES"
                     /locus_tag="VCX65_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEP5052737.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            40206..41837
                     /gene="groL"
                     /locus_tag="VCX65_000243"
     CDS             40206..41837
                     /gene="groL"
                     /locus_tag="VCX65_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEP5052738.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF"
     gene            42088..42354
                     /locus_tag="VCX65_000244"
     CDS             42088..42354
                     /locus_tag="VCX65_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5052739.1"
                     /translation="MNHFGEIFKTFRESKGLRLKDVAKAGISTSQLSRFEKGETDLTI
                     STFMLILDESNMSIDEFMYAVHDFHRDDLNELLSKSEGFRNNSR"
     gene            complement(43077..44576)
                     /locus_tag="VCX65_000245"
     CDS             complement(43077..44576)
                     /locus_tag="VCX65_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEP5052740.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGEKWKDPSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGVSMSATVSASANDAIQKIDPYVKNGLAESSMASVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVTKKAKSYTEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGGVMWLSIGSPRNAPYLPYLGNISRTYEAY
                     QEKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEMKGLEKTWIAEQDKSTKEISD
                     LVVSDPKAAQEKADKISLDRAEKTFKRLKAIEAKLVEEKPQNKKGLNRS"
     gene            44823..46463
                     /locus_tag="VCX65_000246"
     CDS             44823..46463
                     /locus_tag="VCX65_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052741.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNQKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDNSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDRKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALAPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            complement(46552..47553)
                     /locus_tag="VCX65_000247"
     CDS             complement(46552..47553)
                     /locus_tag="VCX65_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEP5052742.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHPVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLNCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKHPLTQEDICVQAKSATFDAVLNAQKARK"
     gene            48130..48510
                     /locus_tag="VCX65_000248"
     CDS             48130..48510
                     /locus_tag="VCX65_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEP5052743.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            48549..50885
                     /locus_tag="VCX65_000249"
     CDS             48549..50885
                     /locus_tag="VCX65_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP5052744.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANH
                     LDSSATKNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            50934..51086
                     /gene="rpmG"
                     /locus_tag="VCX65_000250"
     CDS             50934..51086
                     /gene="rpmG"
                     /locus_tag="VCX65_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEP5052745.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            51100..51276
                     /gene="secE"
                     /locus_tag="VCX65_000251"
     CDS             51100..51276
                     /gene="secE"
                     /locus_tag="VCX65_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEP5052746.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(51513..52286)
                     /locus_tag="VCX65_000252"
     CDS             complement(51513..52286)
                     /locus_tag="VCX65_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEP5052747.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLIDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLADYQAVFLNHNIHCYF"
     gene            52412..53158
                     /locus_tag="VCX65_000253"
     CDS             52412..53158
                     /locus_tag="VCX65_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP5052748.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLEVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKRNIKIITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSSGGLVLDFVS"
     gene            53174..54154
                     /locus_tag="VCX65_000254"
     CDS             53174..54154
                     /locus_tag="VCX65_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEP5052749.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRKQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            54442..54762
                     /locus_tag="VCX65_000255"
     CDS             54442..54762
                     /locus_tag="VCX65_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEP5052750.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLIKEIIDLRKE
                     LATK"
     gene            54790..55098
                     /locus_tag="VCX65_000256"
     CDS             54790..55098
                     /locus_tag="VCX65_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP5052751.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDKSEAICKDNDIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            55108..56412
                     /locus_tag="VCX65_000257"
     CDS             55108..56412
                     /locus_tag="VCX65_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEP5052752.1"
                     /translation="MAKMNMQNIIKPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSDVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGIIGAIVIGLTVGAVYTTFIR
                     RHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQASEES"
     gene            56623..59040
                     /locus_tag="VCX65_000258"
     CDS             56623..59040
                     /locus_tag="VCX65_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEP5052753.1"
                     /translation="MIETKSPYFGHLTDRMAHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAKTAKPERQAELLDIARICDKVPYEPAKTFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDTIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTPEELWHALESDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            59053..59721
                     /locus_tag="VCX65_000259"
     CDS             59053..59721
                     /locus_tag="VCX65_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEP5052754.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVIAQDYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAINRENA
                     DSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RKSI"
     gene            59778..60866
                     /locus_tag="VCX65_000260"
     CDS             59778..60866
                     /locus_tag="VCX65_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEP5052755.1"
                     /translation="MKVFASPSRYIQGKNALFTNAKTLKQLGNSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(60948..61457)
                     /locus_tag="VCX65_000261"
     CDS             complement(60948..61457)
                     /locus_tag="VCX65_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEP5052756.1"
                     /translation="MSTDHHLREVSYQLLAERGVSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGNSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            61821..62636
                     /gene="sdaB"
                     /locus_tag="VCX65_000262"
     CDS             61821..62636
                     /gene="sdaB"
                     /locus_tag="VCX65_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HEP5052757.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            complement(62877..63719)
                     /gene="ropB"
                     /locus_tag="VCX65_000263"
                     /gene_synonym="rgg1"
                     /pseudo
     CDS             complement(62877..63719)
                     /gene="ropB"
                     /locus_tag="VCX65_000263"
                     /gene_synonym="rgg1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="RopB (Regulator of Protease B) is a paralog of the
                     quorum-sensing transcriptional regulators Rgg2 and Rgg3,
                     which bind short, hydrophobic peptides encoded by genes in
                     their respective vicinities. RopB binds the leaderless
                     short peptide SIP (SpeB-inducing peptide), with sequence
                     MWLLLLFL.; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     RopB/Rgg1"
     gene            64218..64388
                     /locus_tag="VCX65_000264"
     CDS             64218..64388
                     /locus_tag="VCX65_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052758.1"
                     /translation="MDNPKKDKGLSLGVVDPITILITESVINKMRTVPYHLKKLSSTT
                     YCLLADLAYQSA"
     gene            64660..65856
                     /gene="speB"
                     /locus_tag="VCX65_000265"
     CDS             64660..65856
                     /gene="speB"
                     /locus_tag="VCX65_000265"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HEP5052759.1"
                     /translation="MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWESQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            65858..66163
                     /locus_tag="VCX65_000266"
     CDS             65858..66163
                     /locus_tag="VCX65_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HEP5052760.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHS
                     GGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMIEAYQTQINSLD"
     gene            66641..67570
                     /gene="prsA"
                     /locus_tag="VCX65_000267"
     CDS             66641..67570
                     /gene="prsA"
                     /locus_tag="VCX65_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEP5052761.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTIAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(67846..68082)
                     /locus_tag="VCX65_000268"
     CDS             complement(67846..68082)
                     /locus_tag="VCX65_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052762.1"
                     /translation="MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPAAHGPCD
                     DIHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG"
     gene            68518..71598
                     /locus_tag="VCX65_000269"
     CDS             68518..71598
                     /locus_tag="VCX65_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEP5052763.1"
                     /translation="MTNCKYKLRKLSVGLVSVGTMLIAPTVLGQEVSASSSTESSTTT
                     ANTGTGTASGMTATTPSATTDTGEAAGSGARSEANGASSVVSSEESQSSGTTPASPQA
                     QTAPAATSTSSASSSNEKTPKTATTTTSSTPVASTSNNSNKVTSTEAETQTMDVERYT
                     VDKENSKLNIKDGKTPKTRSSVNKDTKLIRNRDDKQRDIVDVTRTVKTNEDGTIDVTV
                     TVKPKQIDEGADVMALLDVSQKMTKENFDKAKEQIKKMVTTLTGEPTDGKENHNRRNS
                     VRLMTFYRKVNEPIELTAENVDKTLDEVWKKAKEDWDWGVDLQGAIHKAREIFNKEKE
                     KKSGKRQHIVLFSQGESTFSYDIKNKSDITKTKITEKVTTSSPLFPWLPIFNHTNRKA
                     EIIGDLEKVLDMAEKVGISLPSSLKSAVKALGLTNSVIGSILGKGLTEYLGLTEYSSD
                     NLDGGGFDYSKRVGEGYYYHSFSDRKYENTMPLEEAIRTALASNFPKLTDNWFFDILN
                     SFVNKDTVEKAKLDVIMKVLNSIFYKREYRYYNHNLSAIAEAKMAQQEGITFYSVDVT
                     DLNSASKRVRRQAAVRKGTKEEENKKNEEERNTKFDTYLKKMSEGNNFLSNVEERDKF
                     KDTLTELTIKDEFTDKVTVEKDSWSKSITDGLKNSNNNNVKHQQANTSTWSFFSSSKE
                     SLTWIISKEQLKEAFEKNGSLTFKYKLRVNKDKLLDKDKKRTKRDTPTENKTSVTADI
                     ISNTVDYKINNQEVKGNKLDAVKLTYTKETVPVPDVEGEVVPIPEKPLVEPMTPLYPA
                     IPNYPTPQLPKDEDLEISGGHGPIVDIVEDTGTGVEGGAQNGVVSTQENKDPIVDITE
                     DTQPGMSGSNDATVVEEDTAPKRPDVLVGGQSDPIDITEDTQPSVSGSNDATVVEEDT
                     VPKRPDILVGGQSDPIDITEDTQPGMSGSNDATVIEEDTKPKRFFHFDNEPQAPEKPK
                     EQPSLSLPQAPVYKAAHHLPASGDKREASFTIVALTIIGAAGLLSKKRRDTEEN"
     gene            71778..73715
                     /locus_tag="VCX65_000270"
     CDS             71778..73715
                     /locus_tag="VCX65_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEP5052764.1"
                     /translation="MTKKFIKSAVILGLASITISMTQPVEAISNSLEYQAQYERVKEE
                     LDALKEKGPKLGERSLYFRLVNKFLSWFGQVWDPLAIKETDYLLDLIGQVNYLVSNTE
                     FQAPEYKDAKNKLDLAVAGYDLYLAREKKRGDAPDYQVTQLTLEQLKTIKKKIREALE
                     TFAQEVKTIQQKNPDLFPHAYVLNAKSKDITDKAQPFLVNSYYDVFYKQFLFTNTNDG
                     YNYNKEADNLTSYQNLIKELLGLKAEIDQLTKGKTGDDRLEMLMWQSKFTLSDSRKKS
                     HLSAYYTQGEYVDKVVLSEEAPNLRTAKEKVKTLKGILHDYYVETNKPEKAKKYHVED
                     ETLPSQPEAPATPEAPAPAPVPVPGQKPAEDERSPQATEPANPSKEDSSTDASQGSHD
                     SENPATDSPSQPQAPDQGNHQSQVPNAKPQTDKTDTPNAPAIPQDTPKAPEAGGQSGP
                     AGNTEEKAPDSGPKESDQSSSKESPSVGEDTTPNQPDVLVGGQSEPIDITEDTITDAP
                     PTVSGHNASTQPQSVVEDTAPQRPDVLVGGQSEPIDITQDTQPGMSGSNDATVINEDT
                     KPKRVFHFDNKEPQASEKAAEQKLAPHDSHTTPQASDDTAAPHLPASGDKPEKVFALA
                     ALTMVAAAGLLSKKRRNTDKN"
     gene            73857..74153
                     /locus_tag="VCX65_000271"
     CDS             73857..74153
                     /locus_tag="VCX65_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HEP5052765.1"
                     /translation="MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADVLDLAPIMYKHM"
     gene            74302..74586
                     /locus_tag="VCX65_000272"
     CDS             74302..74586
                     /locus_tag="VCX65_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEP5052766.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            75020..76288
                     /locus_tag="VCX65_000273"
     CDS             75020..76288
                     /locus_tag="VCX65_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEP5052767.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            76275..76949
                     /locus_tag="VCX65_000274"
     CDS             76275..76949
                     /locus_tag="VCX65_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5052768.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            76962..78179
                     /locus_tag="VCX65_000275"
     CDS             76962..78179
                     /locus_tag="VCX65_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5052769.1"
                     /translation="MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            78273..78926
                     /locus_tag="VCX65_000276"
     CDS             78273..78926
                     /locus_tag="VCX65_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5052770.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            78923..80311
                     /locus_tag="VCX65_000277"
     CDS             78923..80311
                     /locus_tag="VCX65_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEP5052771.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKR
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLM
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            80413..82038
                     /locus_tag="VCX65_000278"
     CDS             80413..82038
                     /locus_tag="VCX65_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP5052772.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNNTSSTDQPTTAD
                     TDTDDESETAKKDKKSKETASQHDTQKDHKSSHTHLTPPSNDTKQTDQASSEATDKPN
                     KDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKT
                     PEKGPEKATDKTPEPNRDAPKPIQPPLAAAPVFAPWRESDKDLSKLKPSSRSSAAYVR
                     HWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRA
                     IVAIAMAESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANK
                     NQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMIKLDQWIDDHGSTPE
                     IPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDR
                     YMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISE
                     SNVMGLGTISYRTFTAEQARLLTYVVGDKLPRP"
     gene            82116..82367
                     /locus_tag="VCX65_000279"
     CDS             82116..82367
                     /locus_tag="VCX65_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052773.1"
                     /translation="MIKKVTTPSQKIKKRVRNGYLLKLGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
BASE COUNT        25752 a        15995 c        17486 g        23488 t
ORIGIN      
        1 atagatttag agaattatta cagtatgtga aaatatatca gaaattgact aaataaaaga
       61 ttctgttata cttgttttat aatattcttt gacgataata tcatttttca acttactttg
      121 tttatgcact gtcactttgc tatgtgcaat acaaagtcat gttatttatc tcatactaaa
      181 aaaataatgg ataatagcta tgttagacta gtgatatgaa gaaatattgc ttttattgaa
      241 tcgttagaga atatgatatt tcaaggagaa aaatagtgat cgagttaaac gatgaattca
      301 tccgaaaaga gacgatagaa ctggccaacg atggcccacg agtacacacc actcaatatg
      361 aaactaaagt acctcggctt cataaatgct atctgctttt ctttagcatt attatcagtt
      421 ctttaacaat tgcagtacct tttttaacag atgcagccaa tggtcttcag tcccaaaact
      481 tatatatagg aatgatgtta acgaaggggc aacttcccta tagtgatgct tttacaacag
      541 gagggctctt ttactttgtt atcattgcat taagttatta tttgggatcg acactttggc
      601 tagtctttgt tcaggtgttt tgtttttact tatctggttt atatctttat aaactcatta
      661 attatatgac atgctttcaa aaagtggctt taactttttc aattagctac tatttgttgt
      721 ctgttagtct tggttttgga ggattgtatc ctactcaact ggctatgcca tttatattaa
      781 tatcggcttg gtttttaact aagtattttg cctgtttagt gaaagatgag gcatttattc
      841 tttttggctt tgtaggtgct cttgcaatgc taattgaccc gagtaccctt atcttttggt
      901 cttttgcttg tgtgacagtt ttttcttata atataagcca aaagcatctt gcaagaggtt
      961 tttatcaact gctagcttcg atttttggga tgattttagt tttttacaca gcaggatatt
     1021 tcattttgaa cttacaagtg ctaaatcctt atttatcaca aacgatgatt tatcctttta
     1081 ctttttttaa atcaggaaac ttatcgttgc tttttggact ggctattcag ttgttcttcg
     1141 ctttggggct tggtcttttg acaggaatgg ggaatgtcat taggcgattt aaaaacaatt
     1201 ctgatagggt cgtcaagtgg ctatttgtca tggtcattct agaatctata cttgtggcta
     1261 tattttcaca agactatcgc ccctatcatc ttttacctct tttacctttt ggattaattt
     1321 tgactgctat tcctgttggc tatcagtatg gtataggatt aggtcagagt agtcatcgca
     1381 gacgtcatgg taaaaatggt gttggtcgag taatgatgat ttatcttaag agacactttt
     1441 atttgccaat tttaattgta gggacaatac taatctgttc tacttattgt ttcattagta
     1501 gtattcctct taatcaggag cgtgatcata ttgctagtta tttagaacag aaactaaata
     1561 aaactcaatc tatttatgtt tgggatgata cttctaaaat ttatttggac agtaaagcta
     1621 aatctgtttc tcaatttagt tctcctgaca tcaatacgca aaaagcgagt catcgaaaaa
     1681 tattagaaga tgaactatta gaaaataagg ctgcttatat cgttgttaat cgctataaaa
     1741 acctgcctaa aatcattcaa aaagtattat ctactaatta caaagtagat aaacagataa
     1801 cgacaaaaag ttttattgtt tatcagaaaa agtaatctaa tatcaatata ttgtgttcga
     1861 gcaaaaaact tgacacaata tattgatttt tttagttgtc gtgatataat agttccgtaa
     1921 ggagatttga tatggtaagt ttagaagaag acaaggtgac tgttcaacct gatattaaag
     1981 tgattaaacg agatggtcgc cttgttaatt ttgatagtac aaaaatctat agtgctttat
     2041 taaaagcaag catgaaagta actcggatgt cgccacttgt tgaggctaaa ttagaggcta
     2101 tttctgatcg cattatagca gaaattattg agcgttttcc aactaatatc aaaatttatg
     2161 aaatccaaaa tattgtagag cataagcttc ttgcagctaa tgaatatgct attgcaaaag
     2221 aatacattaa ttatcgtact cagcgtgact ttgcacgttc acaagcaaca gatatcaatt
     2281 tttctattga taaattaatt aataaagatc aaacagttgt taatgaaaat gctaacaaag
     2341 atagcgatgt ttttaatact caacgagatt taactgctgg aatcgtaggg aaatcgattg
     2401 gtttaaaaat gttaccttcg catgttgcta atgctcatca aaaaggagat atccattacc
     2461 atgatttgga ttacagtcct tatacaccga tgacgaactg ctgtttaatt gactttaagg
     2521 gcatgttagc caatggcttt aaaattggta atgctgaagt ggaaagtccc aagtctattc
     2581 aaactgcaac agctcagatc tcacagatta ttgcgaatgt agcatcaagt cagtacggcg
     2641 gatgcacagc tgatcgcatt gacgagtttt tagccccata tgcggagctt aactttaaaa
     2701 aacatatggc tgatgctaag aaatggatcg ttgagactaa gagagaaagc tatgcttttg
     2761 aaaagactca aaaagatatt tatgatgcga tgcagtcttt ggagtatgaa attaatacgc
     2821 tctttacgtc taatggtcaa acaccattta cttctttagg atttggtttg gggacgtctt
     2881 ggtttgaacg tgagattcaa aaagctattt tgaccattcg gattaatggt cttggtagtg
     2941 aacatcgcac ggctattttc cctaaattaa ttttcacggt taaacgtggc ttgaatttag
     3001 aaccagattc accaaactat gatattaaga ctttggcttt agaatgtgcg actaagcgga
     3061 tgtacccgga tatgttatct tatgataaaa ttattgattt gacaggatct ttcaaatctc
     3121 caatgggatg ccgctctttc cttcaaggct ggaaagatga aaatgggcaa gatgtgacct
     3181 caggccgtat gaatcttggg gttgtcaccc tcaatttacc tcgcattgcc atggaatcaa
     3241 atggcgatat ggataagttt tgggagctgt ttaatgagag gatgctaatt agtaaggatg
     3301 ctttaattta tcgtgtcgaa cgtgtcacag aagcaaaacc agcaaatgcc cctattcttt
     3361 atcaatatgg tgcttttgga aagcgtttgg agaagacagg gaatgtaaat gatctcttta
     3421 agaatcgtcg tgcaacagtc tctcttggct atattggtct ttatgaagtg gcgtctgttt
     3481 tttatggtgg tcaatgggaa ggtaatccag atgctaaagc ttttaccttg tcaattatca
     3541 aggcaatgaa acaggcctgt gaggattggt cagatgaata tggttatcat ttctctgttt
     3601 attcgactcc atcagaaagt ttgacagatc gcttttgtcg tttagatacg gaaaaatttg
     3661 gcattgtgac agatattacg gataaagaat actatacaaa ttcttttcac tatgatgtgc
     3721 gtaagagtcc gacacctttt gaaaaattag attttgaaaa agattatcca gaagcaggtg
     3781 cttcaggtgg ttttatccac tactgtgagt atcctgtttt gcaacaaaat ccaaaggcct
     3841 tggaagcggt ttgggactat gcttatgatc gtgtggggta tttgggaacc aatacgccta
     3901 ttgataaatg ctataattgc caatttgaag gcgattttac cccaacagaa cgtggtttta
     3961 cttgcccaaa ctgtggcaat aatgacccta aaacagttga tgtggtcaaa cgtacatgtg
     4021 gttacttggg gaatcctcag gcccgcccaa tggttaacgg tcgccataag gaaatctctg
     4081 cgcgtgtaaa acatatgaat ggttctacta taaaataccc aggcctgtaa actcaagctg
     4141 ggggagagcc cttttgatgg aaatatgata tgcttaaaag gttgcttcat gcaagcaatc
     4201 ttttattgtt taatggtttc ttagcaattg tgagataaga ataactaatc caaaacgact
     4261 aattagctgt tagcaatcgg actataagaa gaaagagata aggaagaaat aatgggaaaa
     4321 tatcaattag actataaagg aatgcagcag gtagaacgct ttcatgagaa gcattctaaa
     4381 aaaaagacgg ataaaaaatc ccgcgttcaa gaacttaagg ctcggttttt agagaagtca
     4441 aaaaaacagg ataactaaag tatccaataa agaaagaagg ttgagtatgc ttaatattgg
     4501 gattgtggga ctaggtgcca tttcacaaaa agcctattta ccatatatga gacagctgag
     4561 tgacattact tggcatctat caacgcggaa tgcagcagta cgtcagcagg tcggtcagtt
     4621 atttggtcac gctattcttt acagtgatgt caaggagttg tcaaaggcaa gtttagatgg
     4681 cgtctttatt catgcggcca catcggccca cgcagagttg gctagtttat ttttaaatca
     4741 ggggatccca gtctttatgg ataaacctat agctgacaat tacctgatga caaagaacct
     4801 ctatgactta gccaaagaaa atcagacttt tctgatggca ggatttaaca gacgttttac
     4861 acctcgtgtc aagaagttgt caagtttgtc aactaagcgt aaagtggctg ttgaaaaaaa
     4921 tgacttgaac cggccaggag atatgacttt taagctcttt gatttcttta ttcatccttt
     4981 agatacagcc ttattcttgt cagaagggac cttactaaaa gggcattttc aatatcatct
     5041 ggaagcaggc ttactgagtc aagttatggt aaccttgatg accgaaagca tgacgactac
     5101 agcttctatg aatttacaat cagggagtcg ccgtgaggta atggaagttc aacgggctga
     5161 agaaacttat catttagaga acttagacga gttatctatt tataaaggta ctgaaaaaag
     5221 ggtgcttggc tttgcttctt gggacactac cttgcacaaa agaggttttg aaacaatgat
     5281 cgatgccttt ttagaagcta ttagcacagg cgtcaatcct gtcagtcctg agtctagtct
     5341 tttaagccac tggatttgtc aacagattgc tgactctcag ctttcttatg gagagttaac
     5401 ggtagagttg cctaaggatt aggaattgat atggaaataa gacgaccgac tttaaaagat
     5461 aaagacgctg tattgtcaat gattaacgaa tttttagagc agaaaagtgc tacagatggg
     5521 ttatggcatt ttaacgtcaa tgactttaac tatgaaacat ggttggaaga ttccttgcga
     5581 caggaaatgg gtttgtccag tcaaggagtg cctgctattc aatacgtcgc atttgatgag
     5641 agaagtcagg ctatcgggtt cttaaatctt cgtttacggt taaatgagag attacttgaa
     5701 aaaggtgggc atattggtta ctctgtccgt cccagccagc gtgggaaagg ttatgccaag
     5761 gagatgctta aacaagctgt cagctatgcg atttccaaga atatcacgac aattttggta
     5821 acttgtgatg agactaatgt tgcaagccga gcagttattg tggctaacgg tggtgtcttg
     5881 gaagatagtc gaggtggaac ggaacgttat tggattgaag aacaaagagg cgataagtga
     5941 tggcagaaaa gtgttggaat aatcctaagc caaaggaatg gcaggcagag gagttaagtc
     6001 aaggccggat tattgactat aaggctttta actttgttga tggtgaagga gttcgtaatt
     6061 ccctttatgt gtctggttgt ttattccatt gcaaggggtg ttataatgct gcgacttggt
     6121 cttttaaggc gggaatgcct tatacgcaag aacttgaaga gcagataatg acggatttgg
     6181 cacagcctta tgttcaggga ctgacacttt taggtggaga accctttttg aatacgggta
     6241 tcttaattcc tctgattaag cgtattcggc gtgaattgcc agaaaaagat atttggtctt
     6301 ggacgggtta tacttgggaa gaaatgatgc ttgaaacacc agacaaactg gaaatgctgt
     6361 ccttaattga tattctggta gatggtcgtt ttgatatcac aaaaaagaac ctcatgttgc
     6421 aatttagagg ctcttctaac cagcgaatta tcgatgttca aaagtctttg gctgctaaag
     6481 aagtgattat ctgggataag ttaaacgatg gggaccaaac ctttgaacaa attagtcggg
     6541 aggatttgct ttaagaagct gacttatcca catgattttt ttgaaaaggt catgtgaaaa
     6601 caggtccttt aagggtgaat tggggagaaa gtaattgtta tttcctggtt ttccccacat
     6661 tatcctcata gttatccaca ggttgtgtat aagttgtaga attgtgaata aagactaaaa
     6721 aagaggccta ggcctctttt ttgatataga caaattcatg atctgttgat aggtctggat
     6781 ggtagtaaaa accagcaaag acaaggcttt taaggctgtc aacagtttgg caattatttt
     6841 ccatacaggc agtgagaaat gcacctcgtg ccttttttga aatggtggaa tgggttttga
     6901 attggccctc tttttctgcc ataaacttgg gacttatcca caattgttta cagtctttgg
     6961 aaaagacatc gtcaaattca ctggataaaa gggaaatcac ttggggatgc tctttggcaa
     7021 actgattata acagggccgc cagtaagact tgaggctttg tccttcaatt tttattctgg
     7081 tgtgaaaatc atggcggtgc tctgcgatag gatgattagc gggaatgata ccgtaaaagg
     7141 atgaggtgat gtaaacttgc tgggtgaggt aagcctgttc ttgggtagtg agcttatcgc
     7201 gcttgatatg gcggtacata aggccattga acagttggta ggcagggtaa gccaagtttt
     7261 gttgagaggc catgtcttgc cagcgttgct gttctttttt agctgcctct tctttgatac
     7321 gataggattt ggccaagtcc tccgtggtca tagctgccat gatttttaaa atggcttggc
     7381 tgtcttgtgg aaggaggtgt gggtgagatt ccttagggat catcatttct tttgcggttg
     7441 gaattaaaaa ggttagcata gtgttattgt agtaaagtta cttgctttct gtcaagaaaa
     7501 ctagtcttgt ccaaggatga cgttcacaca gataccttcc tcgtcttctg tcgtgaaaga
     7561 agaagaatct tcttgtaaaa tagctaggcc gtgtaatctt gcttttttca gagtagctga
     7621 aaaaagcagg ggcgtctcaa tgtgaatggt caagaaggct aagcctgggg caccttcttg
     7681 gtgttttttg aggtaagggg ctgaccagtg attgaatgca aggtgatgat ggtagttccc
     7741 tgaagcaatc cagctagcac ttggaatggt cattttatcg cctaaatcaa aaaccttttg
     7801 atagagaagt gaagaagcca gagcattttt gacactcaga tggacatggc caatgcgtgt
     7861 gtcttgagct agtaaaaagc gcttggggat atctgtcaac tgctccaata tgcttttggt
     7921 atccgtgggc tcagtcacac caataatttg accattgtcg cggatatccc aatgctcaac
     7981 agctttgtca tgataaattt caatcccatt gccctcagga ccgctgaggt agatagcttc
     8041 gctatagccg tgatcagctg atccttctaa agagatacct ctggttaaga aatgattgag
     8101 aacaagtccc aagctatgac gatcaggaac taaaaaggat gtgtgataaa gaccataagc
     8161 cttatttgct ggtaaaggtg tttgtcgtaa ctctaagata acggttttac cgtctgtagt
     8221 caattgacga gatgtcgtgt cttgtgagag aacctgtaaa ccgataatac ttgtgtaaaa
     8281 ggttgtcatc tttgctagat cggtaacatt tagagaaacc gttcctaaag agatggttga
     8341 gttgtaaggg tatgtcatcc tattacctcc aaaaactaat taaatctatc ataatcaatc
     8401 agtttcaaaa agaaaagtag gcacaaataa gtggtatagg cactaaaaag taactcattt
     8461 gtcagcccta tcttgtttct gttctctcta atagtctata atgggttata agttacaaaa
     8521 agatactaag aggagctgct gcctatgctg aaaaaaagac cggcttgtcc cgtagaaaca
     8581 accttatcgg taatcgggaa taaatagaaa ttattaatat taagggactt gctaaaggga
     8641 ccttgcgttt tgggcagttg aagtcctcaa taggtttggt cagtcaaaag gtacttactg
     8701 cacaattaag ggctatggaa gcagacggat tggttcatcg ggaagtgtat gcagaagtgc
     8761 cacctcgggt ggagtattcc ttaacagaaa ctgggttgag cttagctcct gttattgaag
     8821 cgatgtcgga ttggggccaa acttaccaag aaaaacatgc cgatttattt gaagaaggct
     8881 agaggaaaga gttgtccgag catactgaga cttagagaag ctgatagttt ttaaaaaatg
     8941 atattatcaa attctttaca gtttgataaa attacttttt ttctacaaaa agacttgcgc
     9001 tcatctcacg aatatgataa tataatatca agtatgtttg agaaaacaga agctcaggtc
     9061 aagtaagtgc acacttacaa taacacagtt gataatgggg aaactcagag tcaagaaaaa
     9121 gaaaagcaag ccttgcattt tgcaaggctt ttttctgtct ttattttggt ctgcgccgag
     9181 caaaatctaa aaatttaaat ttttccagtt tatggcgact ctcggtgaat tggaattggt
     9241 tattattgga aaggtagact ttggatttga cggaaacaac atgttggtct gatccaaggt
     9301 caagtaaaat tttatcacga tcggttattt ggtcaatggt aacctctttg agggcaaagt
     9361 caatggcgag atggagttcc ttttccaaat attgataaat agaatgctct gcgatttccc
     9421 ttgtcattat tggcaccaaa gttttactaa ggtaatcaat gtctaagacg gaagccacac
     9481 cctcaacaac gcgttggcgt gtaacacgcc agaccaagct gtttttgcta aaaccggtca
     9541 attttgaaag tgtctcatcc acaatcagtt tatcaatggc aatgacgttg gtcttagaat
     9601 ctagatttga gtaagagacg agttcctgat aactagttag ttctgagata gggaacatga
     9661 tctgatgatg tttaatcact tgggtgccac gtccttgttt tttgaggata agacctgcct
     9721 ttgtgagaag tgagagagcc ttgcggacgg tatctcggct agcttggtat tgttgactca
     9781 attctatttc agtaggtaaa aaatcccctt ctttgtaaaa gtctttgttt atttttgttt
     9841 cgaggtcttt ataaatacgt tcatactttg tcatagggta aattaccttt ccatttgtct
     9901 atttttttac agacaacacc ttttatttta ccaaaataat ggcttttttg gcacaaacaa
     9961 cttgtagaca aatttgcaat cgattacaat aaaggtgtca gttagattct atctaagaat
    10021 ttgaatattt cattttgacg ttgcttgtta aaagcaacta gaacaaagga ctaggggatg
    10081 tcacatggga aaatttgaac aggatgctaa gagtcttcta actgctattg gcggtaaaga
    10141 aaacatcaag gctgtcacac actgtgcaac gcgtatgcgt tttgttttga atgataataa
    10201 taaggcaaat gtcaaagaga ttgaaaaaat ctctgtagtt aaagggacat ttaccaatgc
    10261 tgggcagttt caggtaatca ttggtaatga tgttccagtt ttttataatg actttacagc
    10321 tgtttctggt attgaagggg tgtctaaaga agctgccaaa tcagcagcta aaagtaatca
    10381 aaatgcctta caacaggtga tgaccatgtt ggctgagatt ttcacaccta ttattccggc
    10441 gattattgtt ggggggctta ttttaggttt ccgtaatatt ttggagagtg tgccttttga
    10501 atttcttggg cagcaggtcg aaaaagggaa attagttttt gatgcagctg gggatcctgt
    10561 ttggaatacg attgtgaggg tatctccttt ctggtcaggg gttaaccatt tcttgtggtt
    10621 accaggggaa gctattttcc acttcttacc agttgggatt acttggtctg tgacgcgtaa
    10681 gatgggaacc actcaaattt tagggactgt ccttggtatc tgtttggtgt caccacaatt
    10741 attgaatgct tatgcggtag caggaacgcc tgctgctgag attgccaaaa actgggtttg
    10801 ggattttggt ttctttacca ttaatcgtat tgggtatcag gcacaggtta ttccagccct
    10861 tttagctggt ctgtcccttg cttatcttga aattttctgg cgtaaacgga ttccagaagt
    10921 ggtctcaatg atttttgtgc cattcctttc tttgattcca gctttgattt tagcgcatac
    10981 ggtattgggg ccaatcggtt ggactattgg taaagggatt tcctttgttg tgttagctgg
    11041 tttgactggt cctgttaaat ggctattcgg tgctatcttt ggtgccttgt atgctccgct
    11101 agttattact ggtttacatc acatgacaaa tgccattgat acccaattaa ttgctgatac
    11161 tgcaactcgt acaactggtt tgtggccaat gattgctctt tcaaatatcg ctcaagggtc
    11221 agccgttttt gcttattatt taatgaatcg tcatgaagaa cgtgaggctg aaatatcgct
    11281 tcctgcagca atttctgctt accttggggt aactgagcct gccttatttg gggttaatgt
    11341 taaatacgtt tatccctttg tagccggaat gatcggatca ggtattgcgg gtctcttatc
    11401 aacaaccttt aatgttcagg caaattctat tggtgttggt ggcttaccag gtttcatggc
    11461 tatcaatgtg aagtacatga ttccattctt catctgtatg gtagtagcca ttgtggtgcc
    11521 gatgttttta gccttctttt tccgtaaatc acatatcatg actaagacag aagatgaagc
    11581 taaactacct gagacacccg tttcggatgc tcctgtagca actgctccac ataagactat
    11641 gcaaggaaca gttatcactt taacaagccc tttaacgggt gaagttaaag cgttgtctga
    11701 agctgttgat cctgtctttg cacagggagt tatgggccaa ggtgctcttc ttcaaccgac
    11761 agaaggggtg ttagtagcgc cttgtgatgc tgaagtatcg gtcttgttcc caactaaaca
    11821 cgctatttgt ttggtgacga ctgaaggttt ggaattattg atgcatattg gcatggatac
    11881 ggttaactta gatggtcaag gatttgaagc tttggtgaag caaggtgatc aggttaaggc
    11941 tggacaaaca ttgattcaat ttgatatagc agctatttct gaagctggat acgccactga
    12001 aacgcctctt gtggtgacta atcaagatgc ttttacggta actgttgaag gtagtttacc
    12061 gcgtcagatt aaggctaatg ataagttagc agtagcgatg aaaaagtagg tttactaggg
    12121 agaaaacgtt caggaactga gatcagttcc tgaaactatt ttagggagga aaactcatga
    12181 caattgataa aaagaaagtc gtctatcaaa tttacccaaa atcctataag gacacgactg
    12241 gaaatggtgt gggagacttg cgagggatca ttgataaatt gccttactta caagaactag
    12301 gaatagatat gatttggttg aaccctttct accctagtcc acaacgagac aatggctatg
    12361 atgtttcaga ttatacggcg gtcaaccctg attttgggac aatggctgat tttgaagatt
    12421 tggtaaaagc tgctaaggag catcagattg agttaatgtt ggatatggtt ttgaatcact
    12481 gttccacaga ccacgagtgg ttccaaaaag ctttagcagg agacccttat tatcaggatt
    12541 tctttatctt gagagatcag ccgactgatt gggtttccaa atttggtggg aatgcttggg
    12601 cgccttttgg agatacaggc aaatactact tacacttgtt tgatgtgaca caggctgact
    12661 tgaattggcg gaacccacat gttcgtgagg aattggctaa agtggttaat ttttggcgag
    12721 ataaaggagt gaagggattc cggtttgatg tgattaatct gattgggaaa gatgaagagc
    12781 tggtggattg tccggtcaat gatggtaagc cagcttatac ggatcgtcct attactcaca
    12841 cttatcttca tgatctcaat caagccagtt ttggtcagga tgattcgttt atgacagtag
    12901 gggaaatgtc tgccacgact attgataact gtcttttata cacggctccc gaacgtgagg
    12961 agctatccat ggcttttaat ttccaccatc taaaagttga ttatgagaac ggtcagaaat
    13021 ggactattat ggcttttgat tttgcagcgc tgcgagactt attccatgct tggggtgaag
    13081 gcatgagtca gggcaatggg tggaatgcct tgttctacaa taaccatgat caaccacgtg
    13141 ccctgaatcg ttttgttgat gtaacacatt tccgaaacga aggtgcgacg atgttagcgg
    13201 cttccatcca tttgtcacga ggaacgcctt acatttatat gggtgaggag attggcatgc
    13261 ttgatccaga ttttgatagt atggatgatt atgtggatgt ggaaagtctc aatgcttact
    13321 caagcttatt agtctcaggt aaaagtgcag aagaagcctt tgccattatc aaggctaagt
    13381 caagggacaa tgccagaaca ccaatgcaat gggatgctag tgaacatgct ggctttacga
    13441 ctggtaagcc ttggttagag gttggcaaat cttatcgaga catcaatgtc gaaacagaaa
    13501 aagagggacg tattttccct ttctaccaac gcttgattgc tttgcggaag gaactcccta
    13561 ttattgctga aggggactat cgggctgctt ttaaagatag tcaggctgtc tacgcctttg
    13621 aacgccattt aggtgaccag tgtttgcttg ttctcaatca tttctatgct ggtgaggtcg
    13681 aactggaatt acctccacgt tatcaacatg gacaggcctt aatcagcaac tatgagaaag
    13741 tctctatttg tgaaaaagtg atgctgaaac cttatcagac acttgctatt ttagctgata
    13801 actaactaaa agcctgaggt taggcctcag gcttttggtg attgtcacga aaaaagcagt
    13861 tttctcatat atttattttt aaactcttat tttttctaaa taaaaacaat tgagataagt
    13921 tattttagct aaattttggt acaatggaaa agattataag tagagtttaa gataaagatt
    13981 ctacaaattt aaaatgatat aaggagatac gaatgacaac ttatcaagat gatttttacc
    14041 aggctgtgaa tggaaagtgg gctgaaacag cggttattcc agacgacaag cctcgaacag
    14101 gtggattttc agacttagca gatgaaattg aggcattaat gctagacact acagatgctt
    14161 ggttagcagg ggatcatatc cctgatgatg ctattttaaa aaattttgtg aaattccatc
    14221 gtttggtggc tgactacgct aaacgtgatg aagttggagt aagtccaatt ctccctttaa
    14281 ttgaagaata tcagtcctta aaatcttttt cagaatttgt tgctaatata gcgaaatatg
    14341 aattggcagg tttaccaaat gaatttccct ttagtgtggc accagatttt atgaatgctc
    14401 agctgaatgt gctttgggca gaagcaccaa gcattctttt gccagataca acatactacg
    14461 aagaaggcaa caaaaaagct gaggaattgc gtggtatttg gcgtcagtcg caagaaaagc
    14521 ttttacctca atttggtttt tcaacagaag aaatcaagga tcttttggat aaggtaattg
    14581 agctagataa gcaattggcc aagtatgtct tgtctcgtga ggaaggctca gaatatgcca
    14641 aattatacca tccttatgtg tgggctgatt ttaaaaaact agctccagag cttcctttgg
    14701 atagcatttt tgaaaagatt ttaggccaag tacctgacaa ggttattgtt cctgaggaac
    14761 gtttttggac agaatttgca gccacttatt actctgaagc caattgggat ttactcaagg
    14821 ctaatttgat tgtggacgcg gctaatgctt acaatgctta cttgacggat gatattcgtg
    14881 tggaatcagg cgcttattcg cgcgctcttt caggaacacc tcaagctatg gacaaacaaa
    14941 aagcagcctt ttatttggcg caaggaccgt ttagccaagc gcttggcttg tggtatgctg
    15001 gtcaaaaatt ctccccagaa gctaaggctg atgtggaaag taaggtagca cgcatgattg
    15061 aggtttataa gtctcgtcta gaaacggctg attggttagc accagccaca cgtgaaaaag
    15121 ccattactaa attaaatgtt atcacgccac atattggtta cccagaaaaa ttaccagaaa
    15181 cctatgctaa aaaagtgatt gatgagagct tgtcattggt tgaaaatgca cagaacttgg
    15241 ctaaaatcac gattgctcac acttggagta aatggaacaa gccagttgac cgtagtgagt
    15301 ggcatatgcc agcccactta gtcaatgctt attatgatcc tcagcaaaat cagattgtct
    15361 ttcctgcggc aatcttacaa gagccatttt attctttaga tcagagttct tcagccaatt
    15421 atggaggaat tggtgcagtc attgcgcatg agatttcaca tgcctttgac accaatggtg
    15481 cttcctttga tgaacatggt agcctaaatg attggtggac acaagaagac tatgctgcct
    15541 ttaaagagcg tacagataag attgtggcgc agtttgacgg cttagagtca catggtgcta
    15601 aggtcaatgg taaattgaca gtttcagaaa acgtcgctga tctaggtggg gtagcttgtg
    15661 ctttagaagc ggcacaatca gaagaagact tctcagcccg tgacttcttt attaactttg
    15721 cgacgatttg gcgtatgaag gcccgtgagg aatacatgca aatgctagct agcattgatg
    15781 ttcatgcccc gggtgaactg cgaacaaatg tcaccttaac caactttgat gctttccatg
    15841 agacctttga tattaaagaa ggcgatgcta tgtggagagc tccgaaagac cgtgtgatta
    15901 tttggtaatt aggtagttga taaaccttca aatgcctgtg attataaaaa tgactgattc
    15961 tgtaaaacac aggatcagtt ttttgcttcc ttattggtgt ccgttttgac acaacaaaaa
    16021 gacaaccctc aggaaagaag gttgcctttt ttagacttat cagaaataag tgattagttg
    16081 ttaagggcag cagccatagt agctgcaact tctgattcaa agtcgttagc ttttttctcg
    16141 ataccttcac caacttcaaa acgtgcaaaa gcaatcgctt tagcgtttac tgagtcaagg
    16201 taagcttcaa cagttttgct gtcgtccatg atgtaaactt gtgcaagaag agtgtaagct
    16261 tggtcaactt tagtgttgtc aagcatgaag cggtccattt tacctgggat gattttgtcc
    16321 cagatttttt ctggtttgcc ttcagcagca agttcagctt tgatgtctgc ttcagcagca
    16381 gtaatcacat cgtctgataa ttgagctttt gaaccgtatt tcaagaatgg aagagctggt
    16441 ttgtcaacca ttgcacgaga ttcgttgtca agttcgatag cgtggttcaa ttgagcaagt
    16501 tcatctttga tgaattgtgc atcaagctca gtgtatgaaa gaacagttgg tttcattgca
    16561 gcgatatgca ttgatacttg tttagcaaga gcatcgtcgc cgccttcgac aactgagata
    16621 accccgatac ggccaccatt atgttggtaa gcaccgaagt gttgctcatc tgttttttca
    16681 atcaaagcaa aacgacggaa tgagattttt tctccgatgg tagcagttgc attaacgtaa
    16741 gcttcagcaa gagtttcacc tgaaggcata acaagtgcaa gtgcttcatc gttgttagct
    16801 ggtttgcctt cagcgataac tttagcagtt gcgtttacca attcaacgaa ttgagcattt
    16861 ttagcaacaa agtctgtttc agcgttaact tcaacaacag cagcaacgtt accatgaacg
    16921 taaacgcctg ttaaaccttc agcggcaaca cggtcagctt ttttagctgc tttagccatt
    16981 cctttttcac gaagaagttc aacggctttg tccatgtcac catctgtttc aacaagtgct
    17041 tttttagcgt ccataacgcc agcaccagat ttttcacgta attcttttac aagcttagct
    17101 gtaatttctg ccatgtgtag tatcctccaa atgatatttg ttttggtttc aaaaaacgag
    17161 acagagcggt ttgctttctg ccccgtttgg ttttcgattg ttaaagacaa acaaagtttg
    17221 ccataagagt taggaactct gtgctaatta agcgttgtcg ccttcgacaa cttcaacgat
    17281 ttcttcgatt gaatctgctt gaatgtcagc ttcaaaagca acgtctgcat cttcaccttg
    17341 acggccttcg ataatagcgt cagctaattt agcggtgatt aatttaacgg cgcggatagc
    17401 gtcatcgtta gctggaatga tgatatcgat atcatctgga tcagcgtttg tatcaaccat
    17461 cgctacgact gggataccaa gttttttagc ttctttaaca gcaatttgtt ctttatgtgg
    17521 gtcaacaaca tacatcacgt ctgggatacg aggcatatct tcgataccgc ccaagaattt
    17581 ttcaagacga gcgcgttgtt tgttaagaag tgcaacttct ttcttaggaa gaacgtcaaa
    17641 ggttccttct tcttccatac gtttgatttc tttcaaacga gcgatacgtt tttggatagt
    17701 tccccagttg gtaagcgttc cacccaacca acggtggttg atgaagtatt ggcctgcacg
    17761 cgttgcttcg tcagcaactg cttcagcagc ttgtttctta gtaccaacga acaagatgac
    17821 agcatcgttt gctgcagcat cacgaacaaa ttcgtaagct tggtcagcta attttacagt
    17881 ttgttgaaga tcgataacgt ggataccgtt acgttctgtg aagatgtatt tagccatctt
    17941 agggttccag cgacgagttt ggtgaccaaa gtgaacacca gcctcaagaa gttgtttcat
    18001 tgaaattact gccatgagta gtttctcctt tataaaatgt tttttcctct tccagacttc
    18061 gacttgcagg ctaacctagc ggcaacaagc ccacaattgg tctagaatga gtatttgccg
    18121 cctacacgac cctactatat tatcaaaaaa agaggttaaa agcaaggaga aatgctatgg
    18181 attcccttat ttttgagatg actagcttct ttgtttattg gtaagtgtta agacaagctt
    18241 ttgctcattt tgggtgacac ttgccaaatc gttttattta agatatagtg aacttgacta
    18301 atttttggag gcgttttcat gacgaagggt attcgatttc aattgcttgg cagtccccac
    18361 atttttcttg atgacaaaga acaatttttt gcctttgcca aagcaaatgc tctcctttat
    18421 tacttagtgg ttaatggatc tgttagccgc gaggtggcgg cgagtctact ttgggaaaat
    18481 aagaacacgc aaacagcgaa aaagaattta cgaaacgcta tctaccaggt caataaagtc
    18541 ttgcaagctg atgtgattat ttgtcccaat cgcaacctgc tggttttgaa aaaaacactt
    18601 gatatcaaaa cagatattaa cctttttctg gctgatccgc tagctcactt agaactctac
    18661 caaggggagt ttttgcaggg cttttacctt aaaagtggtg aggaatttga tctttgggtt
    18721 tcaaaaatgc gtatgcagta tgaacaggta tacctaaaag cgtgttacca aaaaattgaa
    18781 gaaaagctct ctttagatgc cattgaagat gtcgaggaac atttaaagca gcttattgaa
    18841 cgtgatgaat ttgaagagaa aaattatcag ctcttgatga ggctttatca gcaggggaat
    18901 tgtcctggta aggtcatcga aacttattat cagttggcta atgtgttgga taaggagcta
    18961 gggattcagc caagtttgca gagccaacag atttatcagg aagtggtcgc taaagatcgt
    19021 aatgaacgca aaatcaagca ttttttgcgc aacagtaatc attttttggg gcggattgat
    19081 gagattaagc agctggaaaa ctattttgcc aactgtttgg cctgccaaga ggtaggagct
    19141 ctgctcttaa ttggtgatac agggattggg aaacgaaccc tagccagaca ggtcttagcc
    19201 aatcaaaccc aaacgtttca aattgtcaca gctaaatgtt ttcgtgaaga ggctatggat
    19261 tccttattgc cttggcgtaa tatcttagat ggcctgggag atttggtgat tcaaaaccgc
    19321 ttattgacca ccaaagcttg gaaggctgct cttaaacgct gttttcctgt ggcaaccatt
    19381 tttcaagaag ataacaacca accctttatc aaggaccaca ccagcttgtt ggtttccttt
    19441 attgttgata ttttacaaca tttggcagaa atcaaggcgc tggtaatcct tattgaggat
    19501 tgtcactgga tggatgagga tagtttgacc ttgttgcaac gggtcatgaa tcaattggtc
    19561 cactatccga ttgcttttgt cttgaccaag catctaggaa cgactcctga gctcggtctt
    19621 tgtttgaatg ctttgatgag tcaggggcgt ttagaaagca tttgtttgga gccttttaat
    19681 cggcaagaaa gtttggcata tattaacagt caactgggta gtcagccagt gacggaagaa
    19741 gaaatggagc acctctatca agccagccaa ggcaaccctt tctttttgtc agaatacact
    19801 cagaccctac tgcgtcacga aaaatttgtg cctctaacgc ctgccattaa ggctaagttg
    19861 ggtcttaaac tagctaacct aagtagtcgt gatgacgcat tgttaaacta tttgtcttgt
    19921 tgtcggaggc ctatccctct aaataccctc gctcaattga tgttactgcc tttagaagaa
    19981 gtgatcgaga tggtggataa tctggggcac tactatattt tggtggaaga aagcgtagga
    20041 gaggaagtgt tgatttcatt tcgtcagcga attattcaac tctatagtta tgaccgttta
    20101 tctttgtcaa aaaggcgttt attgcacgga caaattgcca aacggttaga agatttactg
    20161 cctattttga caccaagccc tcacttatta gatgacattg cttaccatta tcaggaatca
    20221 cggcaggtga ttaaggcttt ggaatacaac cttaactatc tagatgctac cttgccattt
    20281 cagcatgagc tgtttcccat ttattcaaag agtattggct ccttggaaaa gtcagatcgt
    20341 gaccatcaac gcttaatgga agagcagttt gataggattc gtcaaagcat tgcggatttg
    20401 gaactgacct atgataataa ccgtgatttc cagcagttgc ttattcgttt ttcttacctt
    20461 gaaggccgtt atgatattcg aacagggagg tatcaagaag ggattaaaaa cattcaaaag
    20521 gtcatcgctt tggcaaccga gctaaaacag ccctccttct tgctagaagg ctatcgccag
    20581 ttaattcatt actgtatcca agtggaaaac aagccagaaa tgcgttatta cactagtctt
    20641 tcattggagg cagcggttgc tgctaatcat tttgaggcca ttgcgattag tttgcggtta
    20701 aacggtcttt atcatttgat tattggggag ttaaatgagg cagagcgtct gcttcaacag
    20761 tcgattgact tctttaaggt gacgccaggc ttgcaagcta actatgcgat tcagattgct
    20821 gctgccttag attatttggg ggagatcgcc cagattcgct atcagtttga aaaggccgtt
    20881 gcttaccaaa aacaagccat tgccttgacc gaaaacaagc cagctgagtt atcagtgagt
    20941 attttttata ttggattagg gatttcctac ttttatttag ctgattttga acaagctgag
    21001 caaatcttga gtttggctaa ggaagctttg gtcaatcata gttatccttg gaaagaaacg
    21061 caacttcaaa tttacctggc catgattcaa tggaaaaagg gcaattatca gccagccttg
    21121 accctacttg attacagaga aaccttgatg tctaggtatc gcaatccgcg tgataagggc
    21181 ttggttttct atttgatggc tgtggtcaag taccaattga tatttcaagg agctacccta
    21241 agtcagcagg aaaaagaaat ggcagactac ctgttgtcag aatcctttga gtattattat
    21301 gaaattgcta gtactaacct caacccttac cgagattgtc atttggtgag tgagttgaac
    21361 gatttgcgtc aacaattatc tgctaaaagc taaggaaaac cctctgattc acatcagagg
    21421 gttttagtta tgttgtgcca taatctgtac gaggtaaaag ataaaggtgg ctgctaaatt
    21481 ggcggtgtgg ttatcaatat cgtgtggtgg tgaaacctca accacatcaa agccaactaa
    21541 ttttccgcta gctgcaatgt gttgcaaaac taagacggca agatttgggt caacaccgag
    21601 ggactggata gcactaaccc caggtgcagc accaactgag aaacaatcca tgtcgatagt
    21661 caggtagacc ctttcttgcc cttctaagaa acggtcaatg gctcggcaga ccttttgatg
    21721 gcccatttgg tagatgtctt gacctgttaa aaattgaatg cccttggatt ttgccacaaa
    21781 gtcaaatagg aaaaggttgt tattatgttc ttgaatgcct aaaacgaagt atttaaagag
    21841 gcgtttgtca gcaactgcat cgtcaaacat ttgtcgaaag cctgtccctg aattagggcc
    21901 tgtttggtcg taaggcctta aatcaaagtg ggcgtccata ttgatgacag ctaggtcatc
    21961 acttggggat aggctttggc gtaggcctaa gtagtggccg taggcggttt catggccacc
    22021 tcctaagacg atgggtttga gattgaggtc acacatccgt ttgatggctt tgcttaaact
    22081 gttttgcagt tgttccaaag agcgattggg gccgtcaatg ttacccacat cgtaaaccat
    22141 aacttggttt cctaaatgcc aagggaattt ggctagctgg gttcgtatgg cagctggact
    22201 ttcgaccgct ccgacacgac cattattgat ataaacgccc ttatcacttt taaagccaat
    22261 caaggcaaaa tgcgtccctt caaatggggt tagtgagctg tcgttaaggt caaggaaagt
    22321 catgaccatg ccccatttgg cagtatataa gtcatcgtcg atcccaccat gataatagct
    22381 agtggtggat gggtagtaat cttctagcat gcgcgtcatc tcctttagga ttatgatagc
    22441 aaaataaaac ttacagtcaa cactttcttg gcctttgtca ctggttttta ggaatagcag
    22501 agcaataaaa tcgtctgctt ttggtcccag ttagttagtc taaagaggcc atgacctctg
    22561 ccacagcccc tctagttaaa gaagtacctt attcactaaa attggatact caactcaact
    22621 gcctgctcaa ccgcttcgag gaagcttggg tcttcaatga ctgctgatgc cttgtttagt
    22681 tcatcgtaga tttcgatgtg tttatcgtgt tcgataaagt tgatttcctt gcggaagaga
    22741 tcgtaggcaa ccttagtccc tttacctagt tcatgatttt caggtttgag atcaagagct
    22801 tggcaggctg ccatgatttc agtagccacg atgcggcgag aatttttaag gatttcaaag
    22861 gccttgcgag cagcggtagt gcccatgctg acaaagtctt cttggttttc acaagatggg
    22921 atagaatcca cgctggctgg atgtgccaaa accttgtttt cagaagcaag agaggcacaa
    22981 gcgtactggg taatcataaa gcctgaattg agacctgggt atttgacaag aaaggatggc
    23041 aatttgctga gctggctatt gaccaaacgt tccacgcggc gttcagaaac atttccaatt
    23101 tcagaaatgg cgatgcctaa gaagtcaaat ggctgtgcca ttggttctcc gtggaaatta
    23161 cctcctgaaa taacgtggcc atctttacag ataattggat tatctgtgac agaattgatt
    23221 tcaatgtcaa ctttggattt gacataggcg atactgtctt tgctagcccc atgaatttga
    23281 ggcatgcagc gcaaggtgta agggtcttgc acacgagatt gagtagctac ggttgtgttt
    23341 tggctgcctt caatgaggtt tcggatattg cgggctgttg ccaactggcc gctttgtggg
    23401 cgaatggtgt gaaggttttc ttcaaatgga ctagtaatcc cgttatgcac ttcaagggat
    23461 agggcaccag ctaggtctga cagtttcaat aattgaatgg cgtcataggt tgcaagggca
    23521 ccgattgcag tgagaacagt tgttccgttg ataagggcga gtccttcttt agcggctaaa
    23581 gaaatcttgt caataccagc tttatcaaga gcttcttgac cagaaagaag ctctcctttg
    23641 tagtaagctt tccctagacc aagcatagga agcaccatgt gagcaagcgg cgccaaatct
    23701 cctgaagccc ctagagaccc tttttcagga atgtaaggat gaaccctttt gttgagcagt
    23761 tccaacagct tttcaatggt ggatagacga ataccagaat accctttgac gagagagttg
    23821 atacggatca gcatgatagc tctcacggca tcttctggca atgggtcacc aaatccacta
    23881 gcatgggtac gaatcaaatt ttcttggagt tggactgtat cttctggtga gatgcttacg
    23941 ttacaaaggg atccaaaacc agtggtcacc ccgtaaacca cccgtttttc actgacaatg
    24001 tcatcaacaa ttttacgaga ggcattcaca gcttcaatag cactatcatc aatgcgacag
    24061 gctacgcctt ggcgagcaat cgcaatcacg tcttcgatag taaggctttc gccatctaaa
    24121 ttaatcactc ttgtcatagt ttttctccta gatttgttcc ttagggggca tttggtccat
    24181 ttggtggtta cgtccgtgca taaggtagta cacactactt gcaatgatga caccaactgc
    24241 accataaaca aagttcattg ggttgtcacc ccaaatcata actaaactaa cgataactgc
    24301 aagaattggg ataataggac caaatggtac tcggaagatc acattagcat cgggatcgtc
    24361 cttccgtaat ttcataacgg ctagtgctgt tggaatgtat tggaagaagc ggaaaacaac
    24421 actgagtttt gctaagtttt caaatgagcc agtaagtagg agtacaatgg caattgctcc
    24481 tgaaaccaag atagcaacga gtggtgcgcc attttgattt tgcttggcaa tagcagctgg
    24541 taagagccct tcatcagcaa tggcagcacc gtaacgtggc accatgatgg attctcccat
    24601 gttaagacct gtaatggaaa ttaaagcacc gattgagacc atccaagcgc cagcagggcc
    24661 tatcatttta acaaaggcat cttgaacagg tgcattggtc atcatgattt gagagccaag
    24721 catggcaatg gttccaccga taatcagcat atataagaca gagacgatac tgattgatcc
    24781 taaaagagca cgcggtacat ttttttcagg ggcacgcatt tccccagcga caatagagag
    24841 ggtttcaaaa ccgataaagc catagaagat ataaacagca gtattggaga tagcccctaa
    24901 gaggttagtc cctggttcca actgaacaaa tggggtaaag ttaggaagcc cgtttttgat
    24961 gaaaaaaagg gtacaggcac aaaaggcaac gattggaatt aacttagcaa tggtggctgt
    25021 gatggtgaca attttagagg ttttcaaacc agcgatattc atcaaagata gtaagatgat
    25081 taacccaata ctaagtggaa tgtgccaacc ttcaaaggca gggaaagtaa tgataaacat
    25141 tctggcaaac ccagctgcca tggctgccca agcgaagata gtaacggtcc aaccaaggaa
    25201 gccaacgtta aagccaataa aatcaccaaa agctcgtttg gaatattgga aggctccgcc
    25261 gtttttccca aaataaccag agacttctgc aaaacaaact gccaacatga tggtcaaaat
    25321 agctgttcca aacataacag cgatggatgc agggccaagg cccttgtaaa tggccctagg
    25381 taagagaaaa ataccagagc cgataacggc attgatcccg taaagagtgg caccgctcaa
    25441 gctaaacttt gcctgttctc tttcttgttc gttcatgtga tttgacgcca taataatgct
    25501 ctcctttttg tttgcaaatt gcgttcaaat ataatggata aggtcgctag gaaatgagga
    25561 gatagtcggt ttaggagggt ccttcttgca cctaacgata gtgatgagct attggttagc
    25621 gatgagaaat aggtagcctt ttgtgatgat gtgtagtgat ttcattggag aagaacaggc
    25681 atgagtagtg tgatgcctat ctttatccca ctaagtctta taccataagc ctgcccaaac
    25741 agctactgga gtttgggcgg ggcttgtttg attggggcaa acttttagat ctgaaaggct
    25801 ggcctcctgc tcgattacca acaagtgatt ggcttcaagc tcttgattcg cctgattggt
    25861 cacagaataa gtcagtttgc ttagggcata aagcagttga cagtccgctt tgggtgcctc
    25921 aaatggtgtg tcagaccaga cgggtaataa ttgcccttgg tattggtcat catacattaa
    25981 attgatgtct tggcagattc cacgactgac gattctggta tcgccttcaa acgcataggg
    26041 ttcaaaagga gttagggaaa tctctttagc atgactcaaa tcactcaatg tgatgggctt
    26101 gtctagggtc attagaatcc tgtgatagcc atcaagtaag gtaaaggttg tctgtcgtag
    26161 ggccacagtt gactttgaga ggcgataaga gaattctctc tttttgtaat ctccatcttc
    26221 gggataaagg aacaattggt tggtttcacc gccagaccag tcagtttgga ggtaatcaga
    26281 gggcgctttg atagttacct ttgtcatttg ttctctcctt gtttccaatt agaatagtcc
    26341 tgtgatgttg ccctcctcgt caatatcaat tgtttcgctg gcaggtactt ttggaaggcc
    26401 aggcatggtc atgatagcac ccgtcagagc aacgataaag cctgctcctg cggacacttt
    26461 gaggttgcta atagtcactg taaagtcagt tggtgcgcca agttttttgg catcgtctga
    26521 gaaggaatat tgggttttgg ccatgcaaat tgggtagttg ccaaagccga ggcgttctaa
    26581 gtcagccagt tcacgtttgg ctgcgggggt caatctaatc cccttaccac cgtaaacctt
    26641 ggtaacgatt ttagtcagtt tggtttcaat gctatcatct tcctcataaa caaagcagaa
    26701 ttgattgtct tgctcggcta gtgccacgac tttttcagct aattcacggc caccagctcc
    26761 gccatttgcc caaacatcag aaatcacaac gtcaacgcca cgtttgtcgc aggcatcata
    26821 gacagcttgt aattcagcat cggtatcaag cgggaattta ttgatcgcca cgacaactgg
    26881 aagaccatag acgtcttgga tattagccaa atgtttgtca aggttaggta aaccatccac
    26941 aacggcctga acattttcag tagccaggtt tgcttttggc acacccccat gcatcttaag
    27001 ggcacgtata gtggctacta ggacaacggc tgctgggcga aggcctgaca tgcgacattt
    27061 gatgtcaatg aatttttcag ctccaaggtc agcgccaaat ccagcttcgg taacggcata
    27121 atcgccatat ttcaaggcta gtttggtggc taggacacta ttacagccat gggcgatatt
    27181 agcaaatggg ccaccgtgaa tgagggctgg tgtgtgttcc agggtttgca cgagattagg
    27241 atgaatcgca tccttgagca gagcggctag ggcaccacca gctttcaagt ctttagctgt
    27301 tacaggttca ccttggtagt tgtaaccgat gatgattttt tcaaggcggg ctttgaggtc
    27361 agaaatattt tcggataggc acaggattgc catgatttca gaggcgacgg taatgtcata
    27421 accatcttca cgaggaaccc cgttgacctt gccttgcaag ccgtcaacaa tatgacgaag
    27481 ctggcggtca ttcatatcca ccacacgttt ccaagtgata cgtctagaat caatgcctag
    27541 gctattgcca tggtgaatgt ggttatcaat caaggcagcc aataagttgt tggcgacacc
    27601 gatggcatga aagtcccctg taaagtgaag gttgatgtct tccattggga caacttgcgc
    27661 gtggccaccg ccagcagctc ctcccttaac cccaaaaaca ggaccaagag aaggttcacg
    27721 aagggcaata actgcttttt ttccaatggc agaaagagca tctaccaatc caacggaagt
    27781 agtggttttg ccttcaccag ctggtgttgg tgagatagca gtgacaagaa tgagtttgcc
    27841 atcaggtttg tcttttaagg cgaccagttg acgggcatca atttttgcct tgtacttgcc
    27901 atagagacag agcgcttcct cgtcaatccc taattgattg gcaaccttac tgataggctc
    27961 catagtgaca gagttggcta tttcaatatc tgataaaacc atagttgctc ctttacttgt
    28021 taaacaatat cgagaatttt cgtgtagatg tcatctgcca agtgacagcc cttgtctaat
    28081 aaggcttgtc ctttttggcg atagtcggta acaaagtctt catctttgat gccagacaga
    28141 ttaatcaaaa cattcaacca agcgctttgt aaacctgctt ttaagtttaa agcagcaact
    28201 cctaagtcgc tagcagcatt tgtattagac ttaccgacag ctgttgcagt gatctcaagt
    28261 gcttcgacca tgagggtcat catctcaaaa ggtgattgtg cagctgtttt caaggccttt
    28321 tgcatggcag ttcgtctagc agccttgtct tcgtcagtct cttttggcat atcaaaaacg
    28381 gcagaaacca ggttgaaggc ttcggtatct ttgtcaatgg ctgcaagcaa gctagcttgt
    28441 agagcggtgc ttttagcatg gatctctgta ataatagctt gataatcagc atactttttc
    28501 ttaccaaggg tcaattcaca gaccatcttg gtcaaggaaa tgccattagc gccagagaga
    28561 gcagcagcag aaccaccacc cggagcaggg gcatctgagc caaggacttt agcgaaatct
    28621 gttaagctta aatcaactaa acccatagag aacctcctaa cctagcaaat ggttttcaag
    28681 aacctgttta gggtagtcaa agtcctcaac ttgtaagtag tattcagcca catcgattaa
    28741 ggccttggct ggcgctaagc cgatgacttc agaaccaata acattcacac cgtagcgacg
    28801 cgcttcaaat ttgatggttt caaaagtacg gtaaagagaa catttttcaa agttaaccat
    28861 gttcatggag acttgggcaa tatggcggtc ttctaacatg acaccgatag ccttacaata
    28921 tttgtagcca ccacctgaac cgcggataat tttagcaatt ttatgagcaa tgtcgatatt
    28981 gtcagtatcc aaattaacat tgaaagcaac caatggcatg cgagcaccaa cggcagttac
    29041 cccagcagtt gggtgaatct tacgatctcc gtagtcaggt gcccaatcct cttccaatag
    29101 tttttctggc atgccttcaa actgaccttt acggatttta gcaaggtttt gacgttctgg
    29161 acgtgtggca gagtcttcat aaaggaagat cggaatgtca agttcacggt taatgcgttc
    29221 tgcgacttgt ttggaaattt cgacacattc ttgtgtagtg atgtctttga ttgggacgaa
    29281 cgggcagaca tcggttgctc ccatacgagg atgttcacca tgatgcttgg tcatgtcaat
    29341 gttttcagaa gcgtatttca ccagttggaa agctgcttct tgaatagact ggtcatctcc
    29401 aactaaggta aacacgctcc ggttgtggct cgcatcagaa gagtagtcga gaagggtcac
    29461 tccaggaata cttttggccg tcgctaccaa accatcgata acagcctgat tttggccttc
    29521 tgagaagttg ggaatacatt caacaatttt tgccatgtta atctcctttt atgtcattga
    29581 gttactcatt aggggaatag gttacctact ttagataacg cttacatttt tagctagcag
    29641 ttattagtga aataattgat ctaccgctga agtcacaagg tcatcatcag ccaagtatgg
    29701 gatagtgatg tgatcagtac ctgcatggag acggttgtat tcaatagcgg tttcaatagc
    29761 gtgctcattt cgggcccagt tacggcgagc tacaccgccc atagtatccc aagcaatagc
    29821 agatttaata atctcatcaa tgcgttcgct gccatctaaa acaagtccga aaccaccatt
    29881 gatggcttta ccaataccag ttccgccacc gttgtgaaga gccactaaac tcataccacg
    29941 cgcagcgtta ccagcgtaac attgcaccgc catatcacag gtcacattgg aaccgtcttt
    30001 aatgtttgag gtttcacgaa atggtgagtc ggtaccagac acgtcatggt ggtcacgacc
    30061 aatcatgaca ggtccaatct tgcctttgcg gaccaattca ttaaatttaa gggcgacagt
    30121 cacacgaccg atacagtctt ggtaaaggat ccgggcttgg gtaccaacta cgagttgatt
    30181 tttctcagca tcacgaatcc agttgtagtt atcacggtct tgatagcggc ggtcaggatc
    30241 gatagcttcc atggcagctt tgtcagtagc caccaagtct tcgtgtttac cactcaagca
    30301 gacccaacgg aaaggtccat agccatagtc aaaaagcata ggtcccatga tatcttccac
    30361 ataggatggc cagataaatc cgtctttgtc gttacgacca ttcttagaaa tttctgtaat
    30421 accagagtcg taaacagact tcataaaggc attgccgtag tcaaagaaat aggtgccatt
    30481 ttcagttaac gtcttaatag cttcaaaatg ccgtgccaag gtatcatcaa ccatttggtg
    30541 gaaggtatct ttatcttctg ccaagagccg ggttctttcg tcaaagctaa tacctactgg
    30601 gcagtagcca ccgtcataaa cgttgtgaca agaggtttgg tcagacaaaa gatcaacatg
    30661 aatctgcttg tcattgacgt actctaaaag atcaacgata ttaccatggt aagcaatcga
    30721 agtggactct ttagcatcta tggctttttg ggctaattgc agagcttctt cagggctctc
    30781 agcaatttgg gtaacccagc cttgcgaatg acgggtttca atccgagatt ggtcaacttc
    30841 agcaataatg gcaactgctt tagcaatttc agcagcctta ccttgtgccc cactcatgcc
    30901 tcctaaacca gatgagataa agagtttacc ggtcaaatca ccatcgtcag ccaccccaag
    30961 tttgagacga ccagcattta agagggtatt aaatgttcca tgaacgattc cttgtgggcc
    31021 aatatacatc caaccacctg cggtcatttg accatagttg gtgacaccca tctcttcagc
    31081 gatttcccag tctttcatgt tgtcgtattc acccaccaaa aggccattag taataatcac
    31141 acgaggcgct tcaggtttgg attggaaaag accaactgga tgaccagact caaccaccaa
    31201 ggtttgttca tcagtcatga cttctaggta ttttttaatc aaacaatatt gcatccagtt
    31261 ggcacaaaca gaaccagttt ctccataagt gactagttcg taagggtaca aggcaatctc
    31321 aaaactcaag ttattgtcaa tcatgacctg catggccttg gcagctgtac aatttccctt
    31381 gtactcgtta atgggtttgc cgtaaatgcg gtcttttgga cgccatctgt aaccatagat
    31441 gcgtcccctt gttttgagtt cttccaaaaa ttctggaatg acttcttcgt ggaacttcgt
    31501 aggtacatag cgtagggcat ttttcaaggc gatttcggtc tgagcctggg tcaatcgaaa
    31561 acctctgtct ggtgctcttc ggataccttc tttgaagaca gtcttttccg gtaaaacatc
    31621 gtctaactta acagtcatag cggcagctat gtcagtttca ctgtaaaatg acatagaaaa
    31681 ctcctcctca actccttttt attgtcgaga ttagtctaac ttagactagt ctataaaaag
    31741 tcaaccacgc tttgaaatgc gaaaaaagtc taaaaaaaaa tcaaaacctc attttttgac
    31801 taaaatttga cgcttaatca gtacacttga ggcatgacag ataaagtcag tcagagttta
    31861 attgttgtta ccaaagttgc agagatcgca actattgagt gggtgagggg ggactagtaa
    31921 tggctattaa tcagttgaca aacgatgtta aaaaaggagg tttttatggt tgctgatgtc
    31981 ttattaacac attttaatca actattttgt ctaaatgatc caggtcatcc tttaactggt
    32041 caagaaatga aaaaagccac tatcgttgaa gatggctata tagccatcaa agacggcctc
    32101 attgtggctc ttggttctgg tgaaccggat gctgagcttg tcggtccaca gactattatg
    32161 cgttcttata aaggtaaaat tgcaacgcct ggtattattg actgtcatac ccatttggtc
    32221 tatggtggca gtcgggaaca tgaatttgcc aagaaattag caggggtgtc ttacttggat
    32281 attttagctc aaggtggtgg tattttaagc acggtgaggg ccactcggtc agccagcttt
    32341 gacaaccttt atcaaaaatc caagagattg ctagactaca tgttgcttca tggagtgact
    32401 actgtcgaag cgaaaagtgg ctacggcctt gattgggaaa cagaaaaacg ccaactggat
    32461 gttgttgctg cgttagaaaa agaccatcct attgatttgg tgtctacgtt tatggcagcc
    32521 catgcgattc ctgaagaata caaagggaat cctaaggctt atctcgatgt gattatcaag
    32581 gatatgcttc ctgttgttaa agaggaaaat ctggcagaat tttgtgatat tttctgtgaa
    32641 aaaaatgttt ttacagctga tgagtcccgc tatctgttaa gcaaagccaa agaaatgggc
    32701 ttcaagcttc gtattcatgc agatgaaatt gcgtctatcg gcggagttga tgtcgcagca
    32761 gagctcagcg cagttagtgc agagcatttg atgatgataa cagatgatgg tatcgctaag
    32821 ttgattggtg ctggtgttat tggtaatttg cttccagcca ccacctttag tttaatggaa
    32881 gacacttatg cccctgctcg caaaatgatc gatgccggca tggctatcac tctctcaaca
    32941 gatagtaatc caggcagttg cccgactgct aacatgcagt ttgtgatgca attaggttgt
    33001 tttatgttac gtttaacacc gattgaagtc ttaaatgctg ttaccattaa tgcggcctac
    33061 tctgtcaatc gtcaggagag ggttggtagt ttgacagttg gtaaagaagc agatattgcc
    33121 atctttgatg ccccaaatat tgattaccca ttttatttct ttgccaccaa cttgattcac
    33181 caagtctata aaaaaggaca actcacggtt gatcgaggtc gtattcttta aaaaatttca
    33241 aaaagaagct ttgagcgtta gctcaaaact tcttttaaat atgctatttt attgacgaat
    33301 caagtagtca aaggcaccga tggcagcagt agcaccagac cccatggaaa taatgatttg
    33361 tttataagct gaatcagtac agtctccagc agcaaagata ccaggaatat tggttgaccc
    33421 atgtttatcc acaatgattt caccgcggtc ggttaggttg acaccactat ctttgagcca
    33481 agctgtgttt ggaacaagac caatttgaac aaagacccct tcaaggtcaa ggtgtttgtc
    33541 ttcaccgcta tcacgctcag tgtagctaag acctgtaaca tggtcctctc caacaatatc
    33601 cttagtagca acatttttga tgatggtcat attgttagtc ttagctgcgc ggtcttgaag
    33661 cactttgtca gctttaagtt caggcaagaa ttctaaaacg taaacgtgtt tagcaagacc
    33721 agccaagtca agggccgctt ctaatccaga gttcccacca ccgataacag caacatcttt
    33781 gccttcaaag agaggaccgt cacagtgagg gcagtaagtc acccctttat tacggaattc
    33841 atcttcacca ggaacattaa tgttacgcca tttggcccca agagctaaga tagcagtttt
    33901 ggcttgtaga accgcaccat tagctagagt aacctcaatg ttttcttttt tctcaataga
    33961 agtagctagt tgtgctttga taatatcaac atcataagac ttagtatggg cctccacttc
    34021 ggccattaat tttggtcctt cagtgtaaag ggtaccaatc atgttttcga tgccgaccgt
    34081 ttccatgacc tgaccaccaa aggtttcagc aagtaaacct gtttttagtc ctttacgagc
    34141 tgcatagata gcagcgctat tgcccgcagg gccaccacca ataacaagga catcatagag
    34201 gcctttatca gcaaaggctt cctcagaaag tgggccagcg atttgttcta agagttgctc
    34261 aatggtagcg cgaccagaag tgaattcttc cccgtctaaa aagacagtag ggacagacat
    34321 aatgcctttt gctttcactt catcttggaa catgccgcct tctaccatag tgtgtgaaat
    34381 cttgtcgttc aagacggaca taatgtttaa agcttgaaca acatctgggc agttatggca
    34441 ggttaagctg acataagttt caaaatgcaa cggacggtca atggccttga tgcgatcaat
    34501 aacatcttga tccacttttg gagcacgtcc agatacttgc aagagagcaa gaataaagga
    34561 cgtcaattcg tggcctaaag gaagaccagc aaagacaacc ccactaccgt gacctttttt
    34621 cgcaacctta aagcttggtt gtcggtctaa agtgatgttt tcaatagaaa tacgctcaga
    34681 catagcagct atttcttcca caaagtcttt gactttttga gactgctcat tgtcaccaag
    34741 ggaaacttgc aaaacaagat cagcttctaa cagggtgagg tattgggcaa gttgttcttt
    34801 aatatcagga cttaatgcca tagctttcct cctaaaattt attaaatttt accaactaaa
    34861 tcaagacttg gtgtcaaagt ttcagcgcct tctttccatt tagctggaca aacttcacct
    34921 ggatgtttac ggacgtattg ggcagcgtga attttatcaa tcaaggtgct agcgtcacgt
    34981 ccaataccat cagcattaat ttccatcatt tggataatac catctgggtc aacgataaat
    35041 gttccacgtt gagcaagtcc gtcttcgcca agcacttcaa aggcttgtga aataaggtgt
    35101 gaagggtcac caatcatagg gtatgtgata gtgccaacca catctgagtc atcatgccaa
    35161 gctttatgaa caaaatgagt atcagtagag acagaataaa cttctacacc aagagatttc
    35221 agtgtttcgt attgctcttg aaggtcaccg agttcagttg ggcaaacaaa tgaaaagtct
    35281 gctgggtaga aacaaaaaac tgcccatttt cctttaacgt cttcatttgt aacagtgatg
    35341 aattttccat cgtgataagc ttgagctgaa aattcagcaa tttcttttcc aattagagac
    35401 atatagttgt cctccttttt tatagtttta tacttgtatt ataaaagaac aacaagatta
    35461 tgtctactca gaaacccttg attttactgg gaaatcagcg attgttttct gacaattcag
    35521 ttgtgaaata aatcacatta attaaaatga ttctaaataa gctgaagacg ccgttaaatc
    35581 aaaggttaat ttaattataa tctacagaaa atgtaattgt tattaaagcg tttacaaaaa
    35641 aacttttttg attccgttaa ggcaacttaa tattatggtt acctaatcgc taatattgta
    35701 acctattttg gcatgagatc agggaatggc tgttatatta attggatatg tcttgtgcaa
    35761 atagtgcttg acggatttgt ggaattaggg taaaataatc tttgttgtgg cggtatagcc
    35821 aagtggtaag gcacggctct gcaaaagctt gatcgtcggt tcaaatccgt ctaccgcctt
    35881 ttatatacaa aacaagcctt gattaatttc gtgaaaacgt tgttaaatca aggtttttat
    35941 tttttgcgac aggataaaaa aagagaaaaa aagaaataaa gtcggtcaaa agtcggtcaa
    36001 atttcccgaa gatgtctttt atagcctgat tattaggtat gaaaaatact atggccaaaa
    36061 ttggtaaacg attgcaaata aaggtcagag ttcttacccc cttaaacgat atgcgttaaa
    36121 agttagttga actgccgtgc acctaacgat agacacggtg atgtgagagc gagtagagtt
    36181 gaatctctac ttgtttatct taccatagtc agctttataa agtaaccacc cattacaatg
    36241 caactatatt cttaatgttt ttaagcatgt tattgacaag tgttataaaa tgtgttactc
    36301 ttagtgagta aattagtttt tgagttagta tttgtgtttc aacatcttta tttctctcta
    36361 tttttacaaa tgatttttag aaaggaagtg gatgtatatg gcacaaggta cagtaaaatg
    36421 gtttaacgct gaaaaaggtt ttggttttat ttcaactgaa aacggtcaag atgtctttgc
    36481 acatttttca gccatccaaa ctaatggttt taaaacgtta gaagaaggac aaaaagtggc
    36541 atttgacgtc gaagaaggtc aacgtggacc tcaagcagtc aatatcacta aattggccta
    36601 atctggttaa agtaactaaa gagaagcaga tgttggaaac aacaactgct tttttgattt
    36661 ctaccagtta cctttaatga ttaagagttg cgtttaaggt cttgtatttg ttataataat
    36721 agtcagtttt agtcaaaatg tattgacgtg gtgctactaa gtttttagag tagcccgcaa
    36781 gcaaaggagt gacagcatgc caaccaaaaa tacttcagac agcattgaag agtatattaa
    36841 agaattatta gctaagtcag gaatagcaga aattaagcgg tccatgctag cagattcgtt
    36901 tcaagttgtc ccaagtcaga tcaactatgt cattaaaacc cgttttacgg agagtcgagg
    36961 ctatgaagta gagagtaaac gaggtggtgg aggctatatt cgtattgcca aggttcattt
    37021 ttcagacaaa caccatctga ttggcaattt aatggcaact attgaagact gtatcagtga
    37081 gcaagttttc acggactcga tacaattgct ttttgacgaa cacttattga cagagcgtga
    37141 gggaaatatc attttggctg tggcgtctga tgatgtttta ggaactgatg gttcaactat
    37201 tcgtgcacga atgctctatc gcttattgca acgaattgac agaaagggaa gcaattaatg
    37261 attatgtatt caacgaagat gcaagacatt tttagacagg cgcagttcca agctgctcgc
    37321 tttgatagcc attgcctgga aacttggcat gttttgttag ctatggtagc tgtagataat
    37381 tctttagcaa atatgatttt aagtgaatat gatgcccaag tcgccataga agaatatgaa
    37441 gctgcagcta ttttagccat gggcaaaacc cctaaggaac agttgtctcg tgtagacttc
    37501 agacctcaat ctaaaacctt gactaacttg ttagcttttg cgcaggctat tagccaaatc
    37561 actagggatc aagaagtcgg ctctgagcat gtcttatttg ctattttatt gaatccagat
    37621 atcatggcga gtcgtttgtt agaaatagca ggctatcaga taaaagataa cggcaatggg
    37681 cagccgcgat tagctgactt gcgaaaagca atagaacgtc atgcaggtta cagtaaggaa
    37741 atgattaagg ctattcacga actacgtaag cctaaaaaaa cgaaaacaca agggaccttt
    37801 tcagatatga tgaagccacc aagtacagct ggtgaattga gtgatttcac aagagatttg
    37861 actgaaatgg caagacaagg tttgttagaa tcggtgattg gacgtgacca agaagtatct
    37921 cgtatgattc aggtactaag tcgtaaaacg aaaaacaatc ctgtcttggt aggtgatgca
    37981 ggtgttggta aaactgcgct tgcttatggc cttgctcaac ggattgcaaa tggcgctatt
    38041 ccttatgaac ttaaggagat gcgtgtccta gaattagaca tgatgagtgt ggtagcagga
    38101 acccgttttc gtggggattt tgaagagcgc atgaatcaaa tcattgatga tattgaagct
    38161 gatggtcaga ttattctttt tgttgatgaa ctacatacta ttatgggttc tggcagtggt
    38221 attgacagta cacttgatgc ggctaacatt ttaaaaccag cattatcgcg cggtactctt
    38281 catatggttg gagcaacaac tcaagaagaa tatcaaaaac atattgaaaa agatgcagct
    38341 ctttcgcgtc gttttgctaa aatattaatt gaagaaccta atacagaaga tgcttatcag
    38401 attttgatgg gcctaaaatt atcttatgag acctaccata atgtctcgat atcaaatgag
    38461 gcagttaaaa cagctgtaaa aatggcacac cgttatttaa ccagtaaaaa tctccctgat
    38521 tcagctatcg atttattaga tgaagctagt gctgctgtgc aaaacatggt gaaaaaatca
    38581 gctcctgaga ctttaacacc aatagaccaa gctcttatca atggtgatat gaaaaaagta
    38641 tctcgcctct tagctaaaga agcaaaaggt cagatgagaa aaccaacacc agtgacagaa
    38701 gatgatattt tggcaacctt gagtaagtta tcgggaattc cacttgaaaa actgacgcaa
    38761 gctgatagta aaaaatacct caatttagaa aaagaactgc ataagcgtgt gattggtcag
    38821 gatgctgctg ttacggctat ttcaagagcc attcgtcgca atcagtcagg tattcgaaca
    38881 ggaaaacgtc ctattggatc atttatgttt cttggcccaa caggagtagg taagacagaa
    38941 ctagcaaagg cccttgcaga agttctcttt gatgatgaag cagcgcttat tcgttttgat
    39001 atgtctgagt acatggaaaa attcgcagcg tctaggctta atggagcacc tcctggttat
    39061 gtcggctatg atgaaggagg tgaactgaca cagaaagtta gaaataaacc ttattcagtc
    39121 ttgctttttg atgaagtgga aaaagcacat cctgatattt ttaacgttct ccttcaagta
    39181 ttagatgatg gtatattgac tgatagtcgt gggcgtaagg tcgatttttc aaatactatt
    39241 attatcatga ccagcaatct tggcgcaaca gccctgcgtg atgataaaac ggtcggtttt
    39301 ggggtcaaag gcattcacca agaccatcaa gctatggaga aacgtatttt agaagaatta
    39361 agaaaaactt accgcccaga atttatcaat cgtattgatg aaaaagtggt ctttcatagt
    39421 ctgacccaag ataacatgcg cgatgtggtt aaaatcatgg tacagcctct gattactaca
    39481 ttggcagaaa aaggtattac ccttaaaatt cagcctttgg ccttgaaaca tttgtccgag
    39541 gtcggctatg atgagcatat gggggcaaga ccattacgtc gaacgctgca aactgagata
    39601 gaagataagc tatcagagct tatcctttct cgagaattga caagtgggca tacgctaaaa
    39661 attggattat catatggcaa attaacgttt cacatagctt aatttccata taaaaggtgg
    39721 atcatccttg atgtcaccaa aaaaagaggt tattcttaca aaaataactt cttttttctt
    39781 gactattttt gaccaagtga taaaatagaa tataaagtta gcactcgatg aacatgagtg
    39841 ctaactttac taaagattct tttattggag gaaaatttca tgttaaaacc attaggtgac
    39901 cgtgtggtcg taagatttga tgatgaaaaa gagcagacag tcggtggttt tgtccttgca
    39961 ggcactcata aagagtcaac acgaaaagcg acagtcctcg ctgtcagtga aacgggtgtt
    40021 cgcactatta caggtgatag cgtgctacct tcagtttcag tgggtcaaga ggttttagtt
    40081 gaaaatgggc atgatttaga agtaaccgta gatgatgaga aagtttctat catccgtgaa
    40141 tctgacatca ttgctattgt tacaaaataa aacgacaaat ctctaaatag aaagaaggat
    40201 tgaatatggc aaaagatatt aaattttcag cagatgcgcg tgctgccatg gtgcgcggag
    40261 ttgatatgtt agcagatacc gtcaaagtaa cgcttggtcc taaagggcgt aatgttgttc
    40321 ttgaaaaagc ttttggttct cccttaatta ctaatgacgg ggtaaccatt gctaaagaga
    40381 tcgaattaga agatcatttt gaaaacatgg gagcaaaatt ggtgtctgaa gtggcttcta
    40441 aaaccaatga tattgctggt gatgggacga ctactgcaac agttttgaca caagccattg
    40501 ttcatgaagg actaaaaaat gtgacagcag gtgctaatcc aattggtatc cgtcgaggca
    40561 ttgaaacagc aacagcaaca gctgttgaag ccttgaaagc cattgctcaa cctgtatctg
    40621 gcaaggaagc tattgctcag gtcgctgcag tatcatcacg ctctgaaaaa gttggagagt
    40681 atatctcaga agctatggag cgtgtgggca acgatggtgt gattaccatc gaagaatctc
    40741 gaggtatgga aacagaactt gaagtggtcg aaggcatgca atttgaccgt ggttacctgt
    40801 ctcaatacat ggtcacagac aatgaaaaaa tggttgcaga ccttgaaaac ccatttatct
    40861 taatcacgga taaaaaagtg tcaaacatcc aagacatttt gccactactt gaggaagttc
    40921 ttaaaaccaa ccgtccatta ctcattattg cagatgatgt ggatggtgaa gcccttccaa
    40981 cccttgtctt gaacaagatt cgtggtactt tcaatgtggt tgctgtcaaa gcgccaggat
    41041 ttggtgatcg tcgtaaagct atgcttgaag acattgctat cttgacaggt ggtacagtga
    41101 ttacagagga tctaggactt gaattaaaag atgctacaat gacagccctt ggacaggctg
    41161 ctaagattac agttgataaa gatagcacag taattgttga aggttcagga agttcagaag
    41221 ctattgctaa ccgtattgca ctgattaaat cgcaattaga aacaacaact tctgactttg
    41281 accgtgaaaa actacaagaa cgtttggcga aattagctgg tggtgtagct gttatcaaag
    41341 taggagctcc aacagagaca gctttaaaag aaatgaaact tcgcattgag gatgctctaa
    41401 atgccacacg tgcagccgtt gaagaaggta tcgttgctgg tggtggaaca gcacttatta
    41461 cggtgatcga aaaagtagct gctcttgagc ttgagggcga tgacgctact ggacgtaaca
    41521 ttgtgcttcg tgctctagaa gagcctgtac gtcaaattgc tttaaatgct gggtacgaag
    41581 gctccgtagt tattgacaag ttgaaaaaca gccctgcagg aacaggattt aatgctgcaa
    41641 caggtgagtg ggttgatatg attaaaacag gaatcattga ccctgtcaaa gtaacacgat
    41701 cagcgcttca aaatgcagct tctgtagcta gtcttatttt gacaacagaa gcagttgttg
    41761 ctaataagcc tgaaccagct gcgccagcgc cagcaatgcc agcaggtatg gatccaggaa
    41821 tgatgggcgg cttctaagct ctctatagca ttaaggatta tgaaaaagaa gttgagacta
    41881 aaggtctgct tcttactatg aaaaaagaac aaagattgga tttcgactca tgatatccca
    41941 tctttgtttt tttagttgtg atataaaatg ccaatctttg tggttacaga cttttaatgt
    42001 attggaaaat atattgtttt tctttgtcat gtgctatcat ggagccaatg aaaagttatt
    42061 cccatatatg cgtggtggag gtctgtgatg aatcattttg gagagatttt taaaaccttt
    42121 agagaatcaa agggattacg attaaaagat gtcgcaaagg ctggtatatc aacctctcag
    42181 ctgtcgcgtt tcgaaaaagg ggagacggat ttaaccatat cgacatttat gctgattttg
    42241 gatgaaagta acatgtccat tgatgagttt atgtatgctg tccatgattt tcatcgtgac
    42301 gacttaaatg aactcttatc aaaaagtgag ggatttcgta acaattcaag atagtgatgg
    42361 cttgaagcag ttacttcatg ctcaactagc atcaactgat aagaaggaaa tgttcacgga
    42421 tatcttttgg catatctagc atgtctaagt ctgctatggc atgccatttt gggagtccct
    42481 cacgcgactc tgtcagtagc tctccttcaa aggattcaca tagaaagtcg taatagacat
    42541 agcactcttt ttttgtcagg cttgataaag ctggaaatac cctttaattg aaggtttaaa
    42601 gctgtcagac ctatttcttc ttttagttct cataaagccg cttcaaagaa agattcacag
    42661 ggctcgactt taccttctgg ctggacccat cctggtaagt tatcgtgttg tctatggagt
    42721 cataaaatca tatcgttatg tttgacacac atattgcccc agtctctaac cgttgctatc
    42781 accagattca ccacctttta gtataagaaa aaaggggtga aagaggtttc ttgttgtttt
    42841 tttggcttaa gatttcttta agtcttatct agtatactaa tgtcattcct taataggata
    42901 agtatttggt tgtagaagta tcgtcttaaa ctaacgctat ctcaaccgat tcccaactta
    42961 ttcacccctc ctataccgat aaggtctcac aaagtgtgag accttatttt ttgacttcag
    43021 ctctagttat ggagaaactt gttgatacaa gcttttttgg gttatgggtt atggtattat
    43081 gatctattca agcctttctt gttttggggt ttttcttcaa ccaacttggc ttcaatagct
    43141 tttaagcgtt tgaaggtttt ttcagcgcga tctagtgaaa tcttatcagc tttttcttga
    43201 gcagctttgg ggtcactgac gactaagtca ctgatttctt tggtgctttt gtcttgttcg
    43261 gctatccagg ttttttccaa gcctttcatc tcatcaatca ctttagttcc aaatggtttt
    43321 ggatgagcag ccacgagatc attaatgtgt gacaccgtcc aataccatga cttatcgtta
    43381 tattgggtgc ttttttcttg ataggcttca taggttctac tgatattgcc aaggtatggc
    43441 aagtaagggg cattacgagg actgccaata gatagccaca tgacaccacc acccaattca
    43501 gcaggaatgt cttttttcag ttggaaaata tgagcttcca tgacattagg atttgagatg
    43561 gggtaagcat aacctttaac agcttttttg gattttggtt tacccttacc gtctaatgcc
    43621 atctgatcaa gtggtttaag atccagcccc tcaaaacgat tacgttgcag tttcatcgca
    43681 tcttctagac taaaggtctt atcagtgctt tggagcaact cataattgct gtctttataa
    43741 gttacttttg aatcagggtc aagtgattta atccctgaga aagagcgaga gcggttggca
    43801 tcgtttagtg gtggattgta agatttggca atatgaaatt taccatcaac ttcggtataa
    43861 gatttggctt ttttagtgac tttttccaca tcttctgagg caatcgtatt ttccttatcg
    43921 ttgaaatcga catgtccgag atagaaggta tttggaaaaa cagcgtattt atcatctggg
    43981 aatttgatgg caacgtattg gtgaccagag agaatttcca tgtaccagat gccatctttg
    44041 tcagccaagg taacaatatt tccttcagca gctccttttt cagtgactat tttagcaatc
    44101 aatgcgacac cttcacgggc tgttttgaca cttggtaaaa tgacactggc catagatgat
    44161 tccgctaagc catttttgac gtaaggatca attttttgga tggcatcatt agctgaagct
    44221 gatactgttg cagacataga gacgccaaac tcattaaaac cagcttcgtc ataaacgcct
    44281 ttattaggtg ttacatcagg aatcgcacta tagcgataag aatgctcagg caatgggtac
    44341 tcaaaaccat tagaggggtc tttccatttt tcgccagcag gattgtcctt tgctagacgt
    44401 acaatgaagt ttttattatg atgtggctca agatcttctg ttcgaccata aagaagagaa
    44461 ccgtctttgg ttaaatcttt gccaataata aaaccagtac aagcataact aacactttga
    44521 agcgaaaagg ctgtcagaat acttaaaact ccaagtgata tttttttgtt tatcatgcga
    44581 atcctcctag taaacgataa cgctttcaca gacattataa aatgctcttt ttaaaaattc
    44641 aagtttttta tgaagtgttt tgaaattgtt agctatctaa atattatgag aattctctct
    44701 tgaattttgg cttaacggcc cctaaaaacg tataggcagt gaactatcta ggtttcttcg
    44761 aaaatccatt agccatttat gatataatag taaagaaaaa catagaaagt tggggtctgt
    44821 tgatgaccaa accatttcat cataagaaac taaaacaaat aactataata gctgcaacta
    44881 gccttttttt attcctgatc ggtggtgcct tttactactc taaaaatcat tgtattaatg
    44941 cctatcttaa agctcgatca gcccaatcag gaccagtttt tgaaaatatc aaagcatatc
    45001 tagtctggga tgatactaat gagcagatca caaatgacga ggcgatgtat actaagttta
    45061 gaaggtatag tcaaaaagaa ttgaggcaaa aaaagcagga tttaaaagcc gctagtcaag
    45121 atagtgccgt tcaagtaaag tctgttggtc gtcgtttttg gatttttcct gattatcgga
    45181 ttgccataaa acccatggat ttaacgataa aaacgaatgt gcctcaagca gacgttcttt
    45241 taaatcaaaa aaaagttgct gtttctgatt cagaacagtt ctcagtaaag cttgatcggc
    45301 taccaacggc agaatatacc gcaagtatca gaggcaaaca caacgggcga aacattaaag
    45361 tcaacaaatc atatgatggt gataatcccg tgctagattt gagtgtgtct tttagaactt
    45421 ttttagtaac aagcaatgct aagcaaggag atctttactt cgatgataac catattggca
    45481 cattaaaaga tggtcaatta caagtagaag attaccctgt tacagaaaac gcacaagctt
    45541 atatgaaaac aacattccca gatggtgagt taagatcaca aaaatatgct ctagctgatg
    45601 ttgaagaagg agcaaccctg gagattttag ttacagatct tttagaagag gacaaagcag
    45661 gggagctatt agtatcagct tttgatcagc tgatgcacta cctcagtaca ggtcaagact
    45721 catctaactt acgtagcgtc tttgaggcag ggtctagcaa cgcattttat aggggattga
    45781 aagagtccat aaaagcgaaa tttcagacag atacaagaaa agccagccgt ctcaatattc
    45841 catctatcct tttgacaaca atgactcaag tgggtaaaac aacttacgtg cttgatttca
    45901 cagctaccta cgaatttttg tatgacaact caacagatcc tgagcagcat acctctggac
    45961 atattaatca agacttgact ggaaaagtga ctgtaaaaaa agttggacag cattacctta
    46021 tcagccagtc cggctctaaa aatattactg ttgttaaaga ggacaatcaa ctcaaagcgc
    46081 catctgtctt tcctgagtct attttgggaa cgtggacagg ccaagccaat ggtttaagca
    46141 tccatatgtc tctagcatca gatggaacaa ttacgactaa agttgaagat cgaaaaggca
    46201 accgttctaa agaaactcgg acagctaaaa ttagtaaagt tgaagacaaa ggcaatggtt
    46261 tttatcttta tacgccagat cctggaagtg acataagcgc cttagctcca gaaggaggat
    46321 tggggggtgc aaatgtcaaa tatgcttatg gtttcaaaat atctggtaaa acagcctctc
    46381 cagtggtgtg gcaggcagca ttaacacatg aatttgatta taccaagcca ctttcgggag
    46441 taactttgca aaagcaacca taaaggatgc aaagccacaa agaacagtag aaacaatgtt
    46501 atcactcaaa tacagtgcta tgaaaacaga taaactcaaa aggctaggag attatttcct
    46561 agccttttga gcgtttaaga ctgcgtcaaa tgtagctgat ttagcttgca cgcaaatgtc
    46621 ttcttgggtt agagggtgtt ttaaacgtaa ttgataagca tggagcatca gtcgagcaca
    46681 atcttttttt ccattagaat acaaaggatc accaaataaa acatgacctt gatgggctaa
    46741 atggactcga atttgatgag tccgtccagt ttgtaattga caattgagta agcttgccgt
    46801 tttgtggaag tttttgacta gagttacctc agtaatagct ttcttgccat ttatcggatc
    46861 gacaacacgt tttctgcggt catgtcgatg gcgaccaatt ggatgatggt aagttaccct
    46921 aggactgtct aaggatccgt gaactagtgc caaatattct cgatggatgt ctcttttttc
    46981 taaaagacga ttaaggattg gtaagataaa aggtgtttta gcaaataaaa tggccccact
    47041 tgtttcctta tccagacgat gaaccacata gcaggtctgt cccgtgtaag cagacacgtg
    47101 gttgagcagc gccaactctg ttggatcatt gccgtgtgtt ttcatccctt caggtttgtt
    47161 aacaataatg atgtgctcat cttcataaag gcaggttact ttttcggcct gccccatcac
    47221 gataatcttt tcaggataat cttcgtgatc gaaaaaaagt ttgacctgat caccgtattt
    47281 aacacaactt tgccagttaa caggatgacc attaataaga acatgttttt tagttctcag
    47341 aaaatgccta attttacggg gaattaacaa ttgttcctct aataatgctt tgaccgtcaa
    47401 ttcttcaaag ggatttttca gtgtgacagt aaaccccttt gatggtttat ttgttgtctt
    47461 cattgagcca gttatggtat ttttcaacaa ggttgatagc catttgggtg gcaagagcag
    47521 cagagaaagc ttcagtacct tcacgctcgt cattagctac ctccaagcga gtctcatcgt
    47581 aaatggcttt tagactttct gcggataagg tttctttaaa agcttggaat ttattcattg
    47641 gttaaacccg tccttctatg tttaatgtga gctcctgatt aatgcaagga attcaatgct
    47701 attatagcat gtttctaatc aaaacgtgcc actcaaaaag gtaaaaacgt tattttgcta
    47761 atccatctaa taagaaagtg tcttaaataa gacctcttga tagagtttgt aacagaaatg
    47821 atatgaaact aggtgctaac gcagaaatag aaaacaacta acgtgttgcg aagttggaac
    47881 agtcataaaa aaatagcaag ataaaactta tcaacacaca gttacctaag acgatgagtc
    47941 aaacaggtat gttctttcaa aacaacccca tgaggttgaa cgacgtatcg gaaaaatacg
    48001 gattagtttg gccttatgat aggtccttct ctatcgtaaa agaagtcaac caaaggtttt
    48061 taatataaaa tattaagaaa aattgttata attatgataa aaacataatc gtaaaataga
    48121 ggaaaaacaa tgaaaacaat tagacgttat gatgttaacg aagatagagg gcatacaggc
    48181 cttgtagaag caggagattt ctattattta aactattgtg tcggcaatgt tggacaagac
    48241 attgaaagtc agattaatgg agcctttgac gagatggagc gccgattagc attggtgggg
    48301 ctcacattag atgcagttgt tcaaatggat tgtctatttc gagacgtttg gaacatacct
    48361 gtgatggaaa aaatgattaa agagcgcttt aatggcagat atcctgctcg aaaatcgatt
    48421 caaacggaat ttgcacatca cggtggacct caaggactac tctttcaagt ggatggtgtg
    48481 gcttattcaa aacatatttc gatgacctaa tcaaggttac tttaagatca tagtggtata
    48541 ataacgttat gagatttcta gaacttttac aaaagaaatt ttttcctaaa gcatatcagg
    48601 aaaaacaatt cttaatgcat caaaaaacgc gtttaacgcc acaacacaat caaaagcagt
    48661 attcgccaaa tgccaatcat ttggactcat cagctaccaa aaactcagaa caagaccctg
    48721 caatagctct gcaacgcagt agagcctatg aaggaagccc taaaagtcgg cccgcttggt
    48781 tgcaaaagtt ggaagctgtt ttgccgtctc ctcaacatcc aattcggcgt ttttggcgcc
    48841 gctatcacat cggaaaactg ctaatgattc tgattggaac tcttgtctta ctcttaggat
    48901 catacttgtt ttacttatca aaaacagcta aagtatctga tttacaagat gccttgaagg
    48961 ctacaactgt tatttatgat cacaaaggag agtatgcagg cagtttatct ggtcaaaaag
    49021 ggagttatgt tgagctcaac gctatttcag atgatcttga gaatgctgtt attgccactg
    49081 aggataggac tttttacagt aatagcggta ttaatcttaa acgcttctta ttggcggtag
    49141 ttacggcggg ccgctttgga ggtggctcaa cgattacaca gcaactggct aaaaatgctt
    49201 atctctcaca agatcagaca attaaacgaa aggcccgaga gttttttttg gcgttagagt
    49261 tgaccaaaaa atacagtaaa aaagatattc ttactatgta ccttaacaac tcctactttg
    49321 gaaatggagt ttggggagtt gaagatgcca gtcaaaaata ttttggaacc acagctgcta
    49381 acttaacact ggatgaagct gccacattag caggtatgct caaaggacct gaaatatata
    49441 acccttacca ttctctaaaa aatgctactc accgtagaga tactgtttta ggagcgatgg
    49501 ttgatgccaa aaagattacc caaacaaaag ctcaacaagc tagagcagta gggctaaaaa
    49561 atcgcttagc tgatacttat gttggtaaga cagatgacta caaataccca tcctactttg
    49621 atgctgttat tagtgaagca atagcaactt atggtctttc agaaaaagac attgttaata
    49681 atggatacaa agtttacacc gagctagatc aaaattacca aactggcatg cagacgactt
    49741 ttaacaacga tgaactattt cctgtttcag cttatgacgg tagctctgct caagcagcta
    49801 gtgttgcttt agatcctaaa acaggaggtg ttagaggtct gattggtcgt gtgaatagta
    49861 gtgaaaatcc gactttcaga agttttaact atgcgactca agcaaaacgt agtcccgcat
    49921 caacaatcaa accactcgtg gtttacgcgc cagccgttgc ttcaggatgg tcaattgaaa
    49981 aagaactacc aaataccgtt caagattttg atggctatca gccacataat tatggaaatt
    50041 atgaatcaga agatgttcct atgtatcaag cattagcaaa ctcttataat attccagcag
    50101 tttctacatt gaacgatatc ggaatcgata aagcctttac ctatggtaaa acatttgggt
    50161 tagatatgag ctctgccaaa aaagagttgg gggtagcttt aggtggcagc gtgacaacca
    50221 atccattgga gatggctcag gcatatgctg cctttgccaa taatggagta atccatcctg
    50281 cgcacttgat taaccggatt gaaaatgcca ggggtgaagt gcttaaaacc tttactgata
    50341 aggctaaacg tgttgtcagc cagtctgttg cagataagat gacagccatg atgctaggta
    50401 ccttttcaaa tggaacagca gtcaatgcta acgtatatgg ctatacacta gctggtaaaa
    50461 caggaacgac agaaaccaac ttcaatcccg acttagcagg cgatcagtgg gttattggtt
    50521 atacgccaga tgttgttatt agtcaatggg taggatttaa tcagaccgat gaaaatcatt
    50581 atctaacgga ttcaagtgca ggcacggctt cagctatttt tagcactcag gcatcttaca
    50641 ttttgcctta taccaagggc agccaatttc atgtagataa tgcctacgct caaaatggta
    50701 tttcagctgt ttatggagtc aatgaaacag gtaatcaatc aggagttgac actcaatcta
    50761 ttattgatgg tttaagaaaa tcagcacaag aagcttcgca atcactatca aaagcagtcg
    50821 atcagtcagg gttacgtgat aaagcccaat ctatttggaa agagattgtt gactatttta
    50881 gatagcttgc agtattttag agatcgtgtt aaaataatag ttacggaggc gttatggcac
    50941 agaaaaaagc gagtctagcg tgtgtcgaat gtggcagtcg taactactct atcggagtga
    51001 gtagcacgcc taaaccaaca cgtctagaag taaataaatt ttgcaaatac tgcaaaacat
    51061 ataccttaca caaagaaaca cgttaaaaag gagagcctga tgggattcat tagcgggact
    51121 tttaaagtct taaaagacac aacatggcca aatcgtaaac aacgttggaa agattttatc
    51181 tcagttcttg agtacacagc tttctttacg gtgattatct acatctttga ccagctctta
    51241 gcaaagagtg tattagcact gattaattta ttttaggtca agattggtag aaatgataag
    51301 cttgcttgga aaagcctagg ctgggagtat tcccagcctt ttttgtagta tcaataatct
    51361 aattagtaag cttttttaaa gcccatactg gtttgagcta ttcaaaagca taaaggtaaa
    51421 ggcaatgtag caacgatctc caaaccaagt tcactaaatt agcttgtaac agagtcaacg
    51481 cataaacagc ctggcctcac ttgcttagca cattaaaaat agcaatgaat attatggttg
    51541 aggaaaacag cctgatagtc tgctaaatct tcgggatgat aagccttgac ctcagccatc
    51601 tcatactccc tacctagaag tttgtacttg ttttctccaa attgatggaa aggtaacagt
    51661 tgcacttggt caatctcaag ctgattaaag agctctgaga aggctttagc atcgtctagt
    51721 gaatcattaa attggggaat aacagggatg cgcaagacga tttcttttcc agcttgaaag
    51781 gcataatgaa tatttttgat aatcaagtca ttacgaaccc cagtcacttt ttggtgtctg
    51841 agctgattat aatgtttcaa atcggtatag ataaagtcta cgtagtcaat aagggtgaca
    51901 aattgctcgt gtttggcaaa ggcggtggtt tcaattgcgg tgtgaagacc tgctgctttg
    51961 gctgctttta acagggctaa ggcaaagtca aattgggcaa agatttcacc ccctgacagg
    52021 gtcatgcccc cacctgactc ttcgtagaaa tcaaggtctt taaggacttc ttcgatcacc
    52081 tcgtccacgg ttttttcctc tccaactatt ttagtattaa gcccatcact tgttaacatc
    52141 tgctcaggtg ctttttgttg ggattcggga ttggcacacc aaggacatct caagggacaa
    52201 ccttttaaaa aaacggttgt ccgaatacca gggccgtcat gaatactaaa atgttggatg
    52261 ttgaaaacaa taccgcgatc agtcataagt gtgaattcct ttcgttgtaa aaccatcata
    52321 ccagataaac gtaaataaat caattacgaa tgaaagtaaa tatctctttt cttttaagaa
    52381 aataactggt acaatgaaag gggggtgaat gatgaatcga ttagaacgta ttattcaact
    52441 ggtttcccag aagaaaaaaa tagatgttaa cagtttatca gagcaattag aagtttcgaa
    52501 agtaaccatt cgaaaagacc ttgataaact tgaaagtaag ggcttgttgc gacgggaaca
    52561 cggctatgcg gtgctaaaca gtggcgatga cctcaatgta cgcttgtcct acaattacaa
    52621 cataaagcga cggattgcag aaaaagcagc tgaattggtg caagacaacg ataccattat
    52681 gattgaatct ggctcaacct gtgccctttt ggcagaagtg ctttgccaga ccaaacgaaa
    52741 tattaaaatc attaccaatt cgtgcttcat tgccaactac attcgtcaat atagtagctg
    52801 tcaaatcatt ttactgggcg gttattacca gcccaattca gaggtgactg ttggtccttt
    52861 attgaaagaa atgatatccc tttttcatgt caatcgtgtc tttgttggaa cagacggttt
    52921 caacaaagat cttggcttta tgggcaagga catgatgcgc tcagaagggg tgcgttacat
    52981 ggcagatgct gctgaggaag tggtgatttt gaccgattcc agcaagtttt caaaaaccag
    53041 tctggtacac cagttgtcat tagctgatgt caatcgcgtc attacagacc aagcactaga
    53101 caagcaaaca caagagttat taagttctgg tggtcttgtt cttgattttg tttcttagaa
    53161 aataggtggc tagatgaaag aagaacgcag acggctcctt gccaaggtgg cttacttgca
    53221 ttatgttcaa ggcaagagcc aaaccttgat ttcaaaggaa atgaatatct accgaacaac
    53281 ggtttgtcgg atgttagcaa aagccaagga agaaggcatt gttcggattg aaattgccga
    53341 ctatgatgct gatttatttg ctttagaaga atacgtgcga aagcagtacg gcttggaaaa
    53401 actagacctt gtgcccaacc aggttgaaga taccccaatg gataccttga caaatgttgc
    53461 taaaacagca gctgaggttt ttagacatgt tgttaaagat ggcgataaga tcggtctgtc
    53521 ctggggagcg actctttctt gcttgatgga tgagttaaat ccaaaagcga tgaaagatgt
    53581 gtttatttat cctttggcag gaggacctag ccatattaat gccaaatacc atgtcaatac
    53641 cctggtttac cgcttggctc gcatctttca tggtaatagc gcttttatga acgctatggt
    53701 cattcaagaa gacaaacact tggctaaggg aatcttacaa tctaaatact ttaacgatat
    53761 tttaacaagc tgggaccagt tagatcttgc cttagtagga attggtgggg agcctaatag
    53821 ccttgagcag agtcaatggc gtgatttatt aaccagctca gatcatgacc aactcaaata
    53881 tgaaaaagcc gttggtgaag tttgttgtcg tttctttgat caggcaggtc agccagttta
    53941 cactggccta caggatcgaa ctattggtat ttcgctagaa cagttgaggc gtgtccctaa
    54001 aacaatggct gttgcaacag gtaaacacaa ggctaaggca atattggcag ccttaaaagc
    54061 aggttttatc aattatctag tgacggataa agagaccatg ctagctgttt tagcgttaga
    54121 tgaagatatt gatcttaata acgttcttct ttaatagaaa ttcaaagata ctatgatatt
    54181 tatagaggcc caagaccaaa cggtcagggc ttttttgttt gatgtgttga taaaacagag
    54241 attgctcaaa tgtgcattta atgtattggc acaaaagtgc attaaacaaa atatagcaca
    54301 aaatatattg accctaaaaa caaaaatgat acaataaact taccaacgaa atgtaaacga
    54361 ttacaaacat aataacatca ccttcgaaaa aaaagactca ttgtcgatac atcacatgaa
    54421 aaagaaaaaa aggagacacc aatgcaagtt attgtaccag accaaatcat tatgggctta
    54481 attttaaatg caggcgatgc caaacaacat atctaccaag ctctgaaatg tgctaaagag
    54541 gacgattatg ccactagtga aaaagaaatg gccttagcag atgatgcctt attagaagcc
    54601 cacaatttac agacccagtt tcttgcccaa gaagctagtg gtaataagtc agagattaca
    54661 gctctttttg ttcactcaca ggatcacttg atgacgacca ttacagaaat taatctcatc
    54721 aaagagatta ttgaccttcg taaagaattg gcaactaaat aagttttcat gactaaaaag
    54781 gagattgaca tgattaaaat tggattgttt tgtgcagcag gattttcaac cggcatgttg
    54841 gtgaacaaca tgaaagtagc tgctgaaaaa aaaggcattg actgtcagat tgaagcctat
    54901 gctcaaggga aattagcgga ctatgcacca ttacttgatg tggcactttt aggcccacag
    54961 gttgcctata ctctggataa atcagaagct atttgtaaag acaatgatat ccctattgca
    55021 gttatcccaa tggctgatta tggaatgtta gacggcaaca aggtgcttga tttagccctt
    55081 agccttgtta aagaatagga gtcaatcatg gcaaaaatga atatgcaaaa catcatcaag
    55141 ccaatcatga catttgtgaa tatgcgcggc atcattgcct taaaagacgg tatgttagcc
    55201 attttacctt tgaccgttgt ggggagtctt ttcctgattg ctgggcagat tcctttccaa
    55261 ggggttaatg atgccattgc tagtgtgttt ggtgctgact ggacagaacc ctttatgcag
    55321 gtttaccatg gaacatttgc tattatgggg ttgatttcct gttttgcaat tggctattct
    55381 tatgctaaaa actcagatgt tgaacctctc ccttcagggg ttctatcctt gtcagccttc
    55441 tttattttat tgagatcatc ttatgttcca gcagaaggtg aagctattgg agatgctatc
    55501 agtaaggttt ggtttggtgg tcaagggatt attggtgcta ttgtgattgg tttaacggtc
    55561 ggagctgttt acacaacatt tatccgtcgt catatcgtca ttaaaatgcc agatcaagtg
    55621 ccacaagcca tcgccaaaca gtttgaagcc atgattccag cctttgtgat ctttaccttg
    55681 tcaatgcttg tgtatattat tgccaagtca gtaacaggtg gtggcacctt tattgaaatg
    55741 atttatgatg tcattcaggt accgctgcaa gggttaacgg gttctcttta tggcgcacta
    55801 ggtattgcct tctttatttc ctttctttgg tggtttggcg tgcatgggca atctgtggtc
    55861 aatggaattg tcactgctct tctcttatca aatctagatg ccaataaggc cttgatggca
    55921 gcaggtgagt tatccctaga caagggtgcc catattgtaa cccaacaatt tttagactct
    55981 ttcttgattc tatcaggttc tggcattacc tttggtttag tggtagctat gatctttgcg
    56041 gctaaatcca aacaatacaa ggctttaggt aaggttgcag ccttcccagc cctctttaat
    56101 gttaatgaac cagttgtctt tggttttcca attgtgatga atccagtcat gttcttgcca
    56161 tttatcttgg ttcctgtctt ggcagctctc acagtttatg gcgccattgc tattggtttc
    56221 atgcagccct ttgcaggagt gacccttccg tggtcaacac cagccattat ctcagggttc
    56281 atggttggtg gctggcaagg agctattgtg caaattctta tactcatcat gtcaacgttg
    56341 gtgtacttcc cattctttaa aatccaagat aatatggctt atcaaaatga acaagctagt
    56401 gaagagtcat gatttagcgt ccacacaaat tcttgagacc atctccagtt agaggtggtt
    56461 ttttagaaaa agaagaacga tttatcaggc ctatattgca caatagtgca aaataaagtg
    56521 actatctctt cttatggtta aggatacgca aaagtcgcaa tatatgataa aatagttacg
    56581 aaagaaacat ttataatttc gtaagaaaga aggagacccc gcatgattga aacaaaaagc
    56641 ccttattttg gacatttaac agacagaatg gctcactatc gtgaagctgt gttagacaag
    56701 aaaccttata ttgatgctga gcgtgctatt ttagccactg aagcctatca aaaacaccaa
    56761 aataagccag caaacctcaa acgcgcttac atgcttcaaa ctattttgga aaacatgacc
    56821 atctatattg aggatgaaag cctcattgct ggtaaccaag cctcttcgaa caaggatgcg
    56881 ccgattttcc cagaatacac tctggaattt gtcctcaacg aacttgatct ttttgaaaaa
    56941 cgagatgggg atgtcttcta cattaccgaa gaaaccaagc aacagctccg agacattgcc
    57001 ccattctggg aaaacaataa cttacgtgct cgctgcgggg tcttgctacc agaagaagtg
    57061 caagtgtaca tggaaacagg tttctttggc atggaaggca agatgaactc tggggatgcc
    57121 catttagcgg ttaattacca aaaactcttg gagcacggct taaagggatt tgaagaacgg
    57181 gcacgagctg ccaaagctgc gcttgatttg accattcctg aaaacattga caaataccat
    57241 ttttacgact ctgtttttat tgtcattgat gcagtcaaaa cttatgccaa acgctatgcc
    57301 aagttggcta gagaactagc aaaaacggct aaaccagaac gtcaagcaga attgttagac
    57361 atcgcgcgca tttgtgataa agtgccttac gaaccagcga aaacctttgc agaggctgtg
    57421 caatctgtct ggttcattca gtgtattttg caaattgaat caaatgggca ttccctatct
    57481 tatggccgct ttgaccagta catgtatcct tatgtcaaag ctgatttgga ggctggccgt
    57541 gaaacagaag acacaattgt tgagcgtttg accaacctct ggattaagac cttgaccatt
    57601 aataaagtac ggagccaagc ccacaccttc tcatcagcag ggagtccact ttaccaaaac
    57661 gtgacgatcg gcggtcaaac acgcgataaa aaagatgcgg tcaacccact gtcttacctt
    57721 gttctaagga gtgtggctca aaccaaattg ccacaaccta acttgactgt tcgttaccat
    57781 aaaggcctag acaatacctt tatgaacgag tgtatcgagg tcatgaaact tggttttggt
    57841 atgccagcca tgaacaacga tgaaatcatc attccatctt tcatcaaaaa aggtgtctca
    57901 gaagaagacg cctatgatta ctcagccatt ggctgtgtgg aaacagcagt tcctgggaaa
    57961 tggggctacc gttgcacggg gatgagttac atcaacttcc ctaaaatttt gctgattacc
    58021 atgaatgacg ggattgaccc agcatcaggc aagcgctttg caaaaggaca cggtcacttc
    58081 aaagacatga catcttatga agaattaaaa gcagcatggg atgccaccct gcgcgaaatt
    58141 acccgcatga gcgtcattgt tgaaaatgcc atcgacctag gtcttgaacg tgaagtacca
    58201 gatattcttt gctcagcctt gacagatgat tgtatcggtc gtggcaagac cttaaaagaa
    58261 ggcggagctg tttacgacta tatctcaggc cttcaagtcg gtattgccaa cctatcagac
    58321 tccctagcag cgctgaaaaa attagtattt gaagaaggtc gattaactcc agaagaactc
    58381 tggcacgccc ttgaaagtga ctttgctgga gagcgcggag aagagatccg acaaatgctc
    58441 atcaatgacg caccaaaata tggtaatgat gatgactacg cagatagttt agttgtcgaa
    58501 gcttacgaca cctacattga tgaaattgcc aaatacccaa atacccggta tggccgtggc
    58561 ccaatcggag gtatccgcta ttctgggaca tcatcaatct cagccaatgt cggacaagga
    58621 aaaggaacct tggcgacacc agacggtcgc catgcaggca caccactagc agaaggctgt
    58681 tcaccagaac acagcatgga caaaaaaggc ccgacttcag tattgaaatc tgttgctaaa
    58741 ttaccaacag atgagattgt cggaggagtg ctactcaacc aaaaagttaa cccacaaacc
    58801 ctggccaaag aagaagacaa actgaaatta atggccttac ttcgtacctt ctttaatcgc
    58861 ctacacggtt atcatatcca gtacaatgtc gtgtcacgtg aaaccttgat tgatgcccaa
    58921 aaacatcctg aaaagcaccg tgacctcatt gtccgtgttg ccggctactc agctttcttc
    58981 aatgtgctct caaaagcaac ccaagatgac attattgaac gtacagaaca cacactttag
    59041 gagaaaataa gtatggaata catgttagac actctagatt tagaagctat taaaaaatgg
    59101 catcacattt tgcctctcgc aggtgtgacc tcaaaccctt ctattgccaa aaaagaaggt
    59161 gacattgatt tctttgaacg gattcgagaa gttcgtgcca ttatcggtga caaggcttct
    59221 attcatgttc aagtgatcgc ccaagattac gaaggcatct taaaagatgc tgctgaaatc
    59281 cgcaggcaat gtggagatag tgtgtatgtc aaagtacctg taaccacaga aggccttgca
    59341 gccattaaaa ccttgaaagc cgaaggctat cacatcacag caaccgctat ttatacgacc
    59401 ttccaaggac tattagccat tgaagctggt gctgattatt tggctcctta ctataaccgt
    59461 atggaaaatc tcaatattga tccagaagct gtcataggac aattagcaga agctattaac
    59521 cgcgagaatg ctgatagtaa gattttggca gcaagcttta aaaatgtggc tcaggtcaat
    59581 aaatcctttg ctctgggagc acaagccatc actgctggcc cagatgtgtt tgaagcagga
    59641 tttgccatgc catctattca aaaagcggtt gacgattttg gcaaggattg ggaagccatt
    59701 catcaccgca agagcattta agaaatagca tcagtagtaa tcacatcatt aggaatcaca
    59761 gataaaggag ttcaacgatg aaagtatttg caagtccatc tcgttacatt caaggtaaaa
    59821 atgccttgtt taccaatgct aaaaccctaa aacaactagg aaatagcccc attttactgt
    59881 gtgatgacgt ggtgtatggc atcgtcggag aaagatttga aagctatttg atagataatg
    59941 gcatgactcc tgttcacgta gcctttaatg gcgaagcctc agataatgaa atcagccgcg
    60001 tggttgccat tgccaaggaa aatggcaatg atgttattat tggacttggt ggtggaaaaa
    60061 ccattgacag cgctaaggct atcgctgact tacttgctgt tccggtgatt attgccccaa
    60121 ccattgcttc aacagatgcc ccaacctcag ccttatcggt tatttatacc gatgaaggag
    60181 cctttgaaaa atacattttc tattcaaaaa atccagatct tgttttggtt gacacacaag
    60241 taatttgtca ggcaccaaaa cgcttattgg cgtcagggat tgcagatggg ttagcaacat
    60301 gggtagaggc gcgtgctgtt atgcaaaaaa atggagacac catggcaggt ggcaatcaaa
    60361 ccttggcagg agttgccatt gccaaagcct gtgagcagac cttgtttgca gatggcctaa
    60421 aagcgatggc tagctgtgac agacaagtcg tgaccccggc cttggaaaat gtcattgaag
    60481 ccaatacact tcttagtggg cttggttttg aaagtgcggg tctggctgct gcacatgcca
    60541 ttcacaatgg ctttacagcg ctgacaggtg ctattcatca ccttacccat ggtgaaaaag
    60601 tcgcctatgg cacgttgacc caacttttct tggaaaatcg ttcgcgtgaa gaaattgacc
    60661 gctacatcga cttttaccaa gctattggca tgccaacaac cctcaaagaa atgcatttag
    60721 acacggctac tcaagaggat ttcttaaaaa ttggccgtca agcaaccatg gcaggcgaaa
    60781 ccatccatca aatgccattt gttatcagtc cagaagatgt agcagcggct ttggttgctg
    60841 ttgatgccta tgttacgagt cgataggcta accaaaaaga gatttcttat ttgccagata
    60901 acctcaaaaa aacaagtcta gggagtcatt tcctagactt gttttactta ttgttggttg
    60961 gtaatagcac ttttagcagg gtcattgtgg gcaatacggc tggcagctgc agccgcaatg
    61021 gcgctaacaa tatcatctaa aaaggtatgg caggagttgc catctttgtg gttgagtttg
    61081 tcaacaatcc ccggttttgt cttgtccaga tacccataat tggtaaaacc gatagaccca
    61141 tagaggttaa caatggataa ggccaggatt tcatcaatcc catacagccc ttggtcggtt
    61201 ttcaagatac taaggagtgg ctcagacagc tggttggctt cagccaattt atccaattct
    61261 accccagtga taatagcatt ttgcacttct cgttttgcaa gcaccgcttc aacgctctct
    61321 aaacattctg ccatggtcaa attgggaata taatcattct gcaaaaaaag caccagctct
    61381 gcaatagctt ctaaagaaac ccctcgttca gccagtaatt gataagaaac ttctcgtaag
    61441 tgatggtcag ttgacatgtg agacctcctt tttttcttta ttgtaacata aaagatttta
    61501 agaaacctct acaacagcta aagaggggat agttcttttt taagagatgt tgactactga
    61561 gaccccctac ttggtaaaag tcaaagaaac gatagtaaag taaccatctt acctaggcct
    61621 aaatacaatc accaccccta ggtgacacac agcacctatt tcaaaaatga tattagtatg
    61681 gcaaaacaaa aagacaacgc cttctttttt ctccttatta tctcgtttaa ttttcatatt
    61741 ttttaaaaaa actattgata aactagttaa gtaagcgtat actatggtta gtgagcgaaa
    61801 ttagaaaaga ggacaagcat atgaatctac ttggatcaag acgggttttt tctaaaaaat
    61861 gtcggctagt gaaattttca atggtagctc ttgtatcagc cacaatggcc gtaacaacag
    61921 tcacacttga aaatactgca ctggcacgac aaacacaggt ctcaaatgat gttgttctaa
    61981 atgatggcgc aagcaagtac ctaaacgaag cattagcttg gacattcaat gacagtccta
    62041 actattacaa aactttaggt actagtcaga ttactccagc actctttcct aaagcaggag
    62101 atattctcta tagcaaatta gatgagttag gaaggacgcg tactgctaga ggtacattga
    62161 cttatgccaa tgttgaaggt agctacggtg ttagacaatc tttcggtaaa aatcaaaacc
    62221 ccgcaggatg gactggaaac cctaatcatg tcaaatataa aattgaatgg ttaaatggtc
    62281 tatcttatgt cggagatttc tggaatagaa gtcatctcat tgcagatagt ctcggtggag
    62341 atgcactcag agtcaatgcc gttacaggaa cacgtaccca aaatgtagga ggtcgtgacc
    62401 aaaaaggcgg catgcgctat accgaacaaa gagctcaaga atggttagaa gcaaatcgtg
    62461 atggctatct ttattatgaa gccgctccaa tctacaacgc agacgagttg attccaagag
    62521 ctgtcgtggt atcaatgcaa tcttctgata ataccatcaa cgagaaagta ttagtttaca
    62581 acacagctaa tggctacacc attaactacc ataacggtac acctactcaa aaataatacc
    62641 aaaaggctag acctctgctc actaggccta gctttttaca tcaaaaaaag caatgactat
    62701 agaaagtaaa aatactagaa aaagcaatga ttgccgtcat tgctttttat gatttgtcaa
    62761 aaagtaaaaa gcaaattgaa aaaatcgccc tggagctgtt gagataaact acaccattta
    62821 ttaagatacc aaatcaaaaa gctaacacca taagagcgtt agctttttaa agagcctcag
    62881 gacagtttat gtttaatggc ttctaggtag gtttgaaaca tatgatggat cgttttgcaa
    62941 ttgagtaatt ggaagatctc taagatctgc acacactttt gctcagcccc ctctttacca
    63001 tttatgaggc caataatgcc atcaaaaaaa gacacacaac accgttcata taagcaatca
    63061 tcatttagct gataatcttc aatttttgcc aaaatctaag aagctttatc atactcttgt
    63121 cgctgaataa acaaaatcaa catattgaca aacatccgaa tcgattcatt cccataatac
    63181 cttagggtat tgtatttatc gaggttcaaa ataacttttg aaaacaccat ctcaataaaa
    63241 caagactcaa aaataaacat acaattatta aaaagcacag tctcatagtg actccaagtt
    63301 tcaatattaa taagatagtt tgacaaataa gtccgctctg tcagacagtc ttcctcagta
    63361 agagttgcta ataacacctt gaccaaggca aaaaggttct tttcctttgt tgacttacta
    63421 tctttataag aatcaaggat atgatttaaa ccttctatgt ttcggcattc aaaataatgt
    63481 tttgccgtat ccatatcaat aaattcttta tattgtttaa agttattact aataaagaga
    63541 aactcatcaa cattgacatt caagttgtct aagatataaa gtaacttttt cgaagaaatg
    63601 tcaagattat ttttaataaa acgataatag gtttgcctag tgagataatc accacaaact
    63661 tgtttaatcg aaatgttttt tgaatgccta atgaattcaa cggtttcacc aatttccata
    63721 tgtcaagcct tcctagttga tgtcaaaaat acgttacgca tgtacctaat acgtaacaag
    63781 ttgaatgttt cggatgatag tcgcttatga taggtgcata aggtcaatag ccagatgcga
    63841 tagttttatc aactgtcata tgttaaacct ttctaatcta atagatgtta aaaatacgtt
    63901 acgtgtgtac ctaatacgta acaaaataat gggttagcaa aataagcagc tatgatatag
    63961 ccataaggtt aaaaggaggc gcctactatg tggttattgt tactattttt gtagttcctt
    64021 ttgcaaaatg gtagtagata aaaatgagaa gtcaataaaa gcattgacaa acaaaagaat
    64081 cattttgttt atattatcag tatttttaag tttcttgtca actgaaatga gcatctacta
    64141 gccacaatag taactaaaag gctaattgtc agtaaaaatg agataaatca gccaggaaaa
    64201 agcctacgag tcaactaatg gacaacccca aaaaagacaa aggactttca cttggtgttg
    64261 tggaccctat cacgatcctt atcacagaat cagttattaa caaaatgaga acggtcccat
    64321 atcatctaaa aaaactgtca agcacaacct attgtttgct agctgatctt gcctatcagt
    64381 ctgcctagta gatacggcag aagataagag atcaaccaaa agatgataag tgcaacgact
    64441 catagcgtct tttgaccaaa accaattaga ctcacatgag atgagaataa ttgggttggg
    64501 ttgtcagtgt caactaaccg tgttattgtc tattaccatt catggtatca gcgacatcgt
    64561 atgataacca tgcgattcag ctaagtaagg aggtgtgtcc aatgtactgt taaaagcaaa
    64621 tgcagtagat taacttattt tgaaagaggt ataaaaaaaa tgaataaaaa gaaattaggt
    64681 atcagattat taagtctttt agcattaggt ggatttgttc ttgctaaccc agtatttgcc
    64741 gatcaaaact ttgctcgtaa cgaaaaagaa gcaaaagata gcgctatcac atttatccaa
    64801 aaatcagcag ctatcaaagc aggtgcacga agcgcagaag atattaagct tgacaaagtt
    64861 aacttaggtg gagaactttc tggctctaat atgtatgttt acaatatttc tactggagga
    64921 tttgttatcg tttcaggaga taaacgttct ccagaaattc taggatactc taccagcgga
    64981 tcatttgacg ctaacggtaa agaaaacatt gcttccttca tggaaagtta tgtcgaacaa
    65041 atcaaagaaa ataaaaaatt agacactact tatgctggta ccgctgagat taaacaacca
    65101 gttgttaaat ctctccttga ttcaaaaggc attcattaca atcaaggtaa cccttacaac
    65161 ctattgacac ctgttattga aaaagtaaaa ccaggtgaac aatcttttgt aggtcaacat
    65221 gcagctacag gatgtgttgc tactgcaact gctcaaatta tgaaatatca taattaccct
    65281 aacaaagggt tgaaagacta cacttacaca ctaagctcaa ataacccata tttcaaccat
    65341 cctaagaact tgtttgcagc tatctctact agacaataca actggaacaa catcctacct
    65401 acttatagcg gaagagaatc taacgttcaa aaaatggcga tttcagaatt gatggctgat
    65461 gttggtattt cagtagacat ggattatggt ccatctagtg gttctgcagg tagctctcgt
    65521 gttcaaagag ccttgaaaga aaactttggc tacaaccaat ctgttcacca aatcaaccgt
    65581 agtgacttta gcaaacaaga ttgggaatca caaattgaca aagaattatc tcaaaaccaa
    65641 ccagtatact accaaggtgt cggtaaagta ggcggacatg cctttgttat cgatggtgct
    65701 gacggacgta acttctacca tgttaactgg ggttggggtg gagtctctga cggcttcttc
    65761 cgtcttgacg cactaaaccc ttcagctctt ggtactggtg gcggcgcagg cggcttcaac
    65821 ggttaccaaa gtgctgttgt aggcatcaaa ccttagtatg gaaatgcatt tcgttagaac
    65881 agaacctgag gcacgccgca tagctgaaac cttttgtgcc gaaaacacac aaacaaaaac
    65941 ccctatgcgc gtgcagcagt taagctatcc atcagacaca gatcactcag gtggtgagct
    66001 atacatctat gctttgtctc ctgctggatt tatcatcgta tcaggagaca ccagagcgca
    66061 caccatttta ggctattctt ttgataataa cctagacctc aaccatgata atgtcaggag
    66121 tatgatagaa gcttaccaaa cacaaatcaa ctctttggat tgatcggtca aagtagcttt
    66181 tgcccccctc accactcgtt taagacgacc gtgtttctaa aataccacta ccttttaagt
    66241 ttcacgccgg cctaagcgag tgtttgtctc atggagcaga ctgtttccat cgaaaagtca
    66301 cccattgata aaggaggtca tcaacgccta ctaatgatga cttccctaag atgccaaggt
    66361 aaaggactga gttctgtaga gatgggactc agtcctttta cgatttttgg gagttattct
    66421 agccataccg tggcaagaaa acaacactta aaaatagcca acgtcagttt ctgttcatac
    66481 atgactacag ccaaacacca caacctaacc tatcctaaac acagtggctt tctaacgaac
    66541 agtcacaacg agcagcaaca ccaaaaagca agattaagct acgtttaaga ctaatgatat
    66601 aagataacag taattattaa tgagaaaaga ggctcaggac atgaaacaaa tgaataaact
    66661 cattacagga gtggtaacgc tggcgacagt cgtgacctta tcagcttgtc aatcatcaca
    66721 caacaacacc aaactcgtct cgatgaaagg agacaccatc actgtcagtg acttctacaa
    66781 tgagaccaaa aacacagaac tcgcacaaaa agccatgtta agcttggtga ttagccgtgt
    66841 atttgagaca caatatgcca acaaagtctc tgacaaagag gttgaaaaag cctataaaca
    66901 aaccgcagac caatacggta catcctttaa gacagtccta gcacaatcag gcttaacgcc
    66961 agaaacctat aaaaaacaaa ttcgcctcac aaaattagtc gaatatgccg tcaaagaaca
    67021 agccaaaaac gaaaccatct caaaaaaaga ctaccgtcag gcctatgacg cttatacccc
    67081 aaccatgacc gcagaaatca tgcagtttga aaaagaagag gatgccaaag cagcccttga
    67141 agccgtcaaa gctgaagggg cagactttgc agctattgcc aaagaaaaaa ccattgcagc
    67201 cgataaaaaa acaacctaca cgtttgactc aggtgaaaca accctaccag cagaagtagt
    67261 tagagctgca tcaggcctca aagaagggaa cagatcagaa atcatcacag cgcttgatcc
    67321 agccacctca aaacgcacct accatatcat caaagtcacc aaaaaagcaa ctaaaaaagc
    67381 agactggaaa gcgtaccaaa aacgcttgaa agacatcatc gtgactggca aattaaaaga
    67441 ccctgacttc caaaacaaag tcatcgctaa agctcttgat aaagcaaatg tcaaaatcaa
    67501 agacaaagca tttgccaata tcttagccca gtttgcaaaa cctaaccaaa aacaacctgc
    67561 ccaaaaatag agggttgcca gtttatttcc ctaaggttgc ttaaaaagac agccctaacc
    67621 atcactcccc ttttcaaaac accgataatg gaaacgtgtc ctatactgat ggtctagggc
    67681 aatgtcataa agctaaagac tctatccaaa taaggataga gtctttaata tttaaaaacc
    67741 agtcagcaaa aaaaattcac gctaagccta gctagaatga ggcttagcgt gaatggtatc
    67801 agtgatagtc cgttaacata gctgattggg agtcagaaac tctaactacc caatctgact
    67861 atacccccag taccagaggt gtctcatcgc agaagtagca atcagataat cgtctgataa
    67921 gctcttgtcc tcaagcaact gatgaatatc gtcgcacggg ccatgagctg ccggtggctg
    67981 atagctagta ggctcatcag ccaaaacttt tttggagtaa cgctttggtc tcagacggcg
    68041 ccagagggtt gagagagggg tgagaaaaaa acgatgggtc atcttggcct ccttgtctaa
    68101 tgatagtcac cttaacagac aaaagtgtca ataatgtcat tttaaggaga aaaagattaa
    68161 aaatcaaggt cacaaacttt cctttgttaa aaaaacgcga ccctaacaaa gaatctaaat
    68221 acctctcgca cttgagcttc tccttgcgca gctatcttgt gcactcagtt gcctccaaga
    68281 taatgataac gataccatca ttatcctata ggctatcgcg acaacccctt ttttcgcctc
    68341 aacgagtctg acacagctgt catgacagaa aaaagacctc tgcctatcta agagaccatt
    68401 aatttttctc tcactaaaaa actgatttta gaaacgaaga agcatggtgt ataatatggt
    68461 gtataataag gttcagaaca attatgacat aataatgaaa gtaaggttaa cgaaacattg
    68521 acaaattgta agtataaact tagaaagtta tctgtagggc tcgtctccgt cggaacgatg
    68581 ctgatagccc cgacagtttt aggacaggag gttagtgcta gtagtagtac ggagagcagt
    68641 accactacag ctaatactgg taccggtacg gcaagtggga tgactgccac tactcctagt
    68701 gctacgacag atactggtga agcagctggg agcggagcta ggagtgaagc taatggtgca
    68761 tcgtccgtag tatctagcga agaaagtcag agttcaggca ctactccagc ctcaccccaa
    68821 gcacagacag ctccagcagc aacgtcaaca tcatcggctt cttctagtaa tgagaaaact
    68881 cccaagacag caactacaac tacatcatcg actccagtag caagtaccag taataatagc
    68941 aacaaagtaa ctagtactga agctgaaaca cagacgatgg acgtggaacg gtatacagtt
    69001 gataaggaaa attcaaagct aaatattaaa gacggtaaga ctccaaaaac taggagtagt
    69061 gttaataaag acacaaaact tattagaaac cgcgatgaca aacagcgtga tatcgttgat
    69121 gttactcgga cagttaaaac taacgaagat ggcactattg atgttaccgt aacggttaaa
    69181 ccgaagcaaa ttgacgaagg cgccgatgtt atggcccttc tagatgtctc tcaaaagatg
    69241 acaaaagaga attttgataa ggctaaagaa caaataaaaa aaatggttac gactttaaca
    69301 ggcgagccaa ctgatggtaa ggaaaatcat aataggcgta attctgtacg tctaatgact
    69361 ttttaccgta aggttaatga gcctatcgaa ttgactgctg aaaatgtaga caaaacatta
    69421 gatgaagttt ggaaaaaagc taaagaagat tgggactggg gcgttgactt acagggagct
    69481 atccataaag ctcgagagat ttttaataag gaaaaagaaa aaaaatcggg taaacgccag
    69541 catatcgtct tgttctctca aggcgaatca acctttagtt atgatattaa aaataaaagt
    69601 gatattacaa aaacaaaaat aactgaaaaa gttacgacct ctagcccact gtttccttgg
    69661 ctccctatct ttaatcacac taaccgaaag gcagagatta ttggtgattt agaaaaagta
    69721 ctagacatgg ccgaaaaagt gggaataagt ttacctagta gtctgaagtc agcagtgaaa
    69781 gcccttggct taactaatag tgtaataggt tctattttag ggaaaggttt gacagagtac
    69841 cttggtttga cagaatatag ttcagataac ttagatggag gagggtttga ttatagtaaa
    69901 cgtgtagggg aaggttacta ctaccacagt ttttcagata ggaaatatga aaatacaatg
    69961 ccccttgaag aagctatcag gacggcctta gcatctaatt ttcccaaact cacagataat
    70021 tggtttttcg atatcttaaa tagttttgtc aataaagata cagttgagaa agctaaatta
    70081 gacgtaatta tgaaggtact taatagtatt ttttacaaac gtgaatatcg ctattacaac
    70141 cataacctgt cagcaatagc cgaagctaaa atggctcaac aagagggcat taccttctat
    70201 tccgttgatg ttactgattt aaactcagct tctaaaagag tgaggcgaca agcagcagtg
    70261 cgtaagggca ctaaggaaga agaaaacaaa aaaaatgaag aagagcgtaa tacaaagttt
    70321 gacacctatc tgaaaaagat gtctgaaggt aataatttct taagtaatgt tgaagagaga
    70381 gataagttca aagatacttt aacagagctg acaattaaag acgaatttac ggataaagtt
    70441 acggtcgaga aggattcctg gagtaaatct ataactgatg gacttaaaaa ttcaaataac
    70501 aataatgtta aacatcaaca ggcaaacaca tcgacatgga gtttcttcag ttcatccaaa
    70561 gaaagcctca cctggattat ttccaaagag cagctcaaag aagcctttga gaaaaatggt
    70621 tctctcactt ttaaatacaa attacgggtc aataaagaca aactattaga taaagataag
    70681 aagagaacaa aacgtgatac acctacggaa aataagactt ctgtaacggc agatatcatt
    70741 tcaaatactg ttgactacaa aattaataat caagaagtta agggtaacaa acttgatgct
    70801 gtcaagttga cttatactaa agagaccgtt cctgttccag atgtggaagg agaagttgta
    70861 ccaataccag aaaaaccact ggtagaacca atgacgcctc tataccctgc aattcctaat
    70921 taccctaccc ctcaacttcc aaaagatgaa gatctggaga ttagtggagg tcatggaccg
    70981 attgtcgata tcgtcgaaga tactggtaca ggtgttgagg gcggcgctca aaatggtgtg
    71041 gtttcaactc aggaaaataa agatccaatc gttgacatca ccgaagatac ccaaccaggt
    71101 atgtcaggct caaatgacgc gacagttgtc gaggaagaca cagcacctaa acgtccagat
    71161 gtccttgttg gtggtcaaag tgatccaatc gatatcaccg aagataccca accaagtgtg
    71221 tcaggctcaa atgacgcgac agttgtcgag gaagacacag tacctaaacg tccagatatc
    71281 cttgttggcg gtcaaagtga tccaatcgat atcaccgaag atacccaacc aggcatgtca
    71341 ggttctaatg acgctactgt tatcgaagaa gatacgaaac caaaacgctt cttccacttt
    71401 gataacgagc cacaagcacc agaaaaacct aaagagcaac catctctcag cttaccacaa
    71461 gctccagtct ataaggcagc tcatcacttg cctgcatctg gagacaaacg tgaagcatcc
    71521 tttacaattg ttgctctaac aattattgga gctgcaggtt tgctcagcaa aaaacgtcgc
    71581 gacaccgaag aaaactaacc ctcgttagtc tagcgaccct aagcctttgg ctttaagaat
    71641 ttctcattat ccccctcaaa caccggtacc tcactgagat ggcgctttaa aaaggcgcta
    71701 atctcaaatc aggtatcccc tacggttgag agggattaat gggtatcaca acaagaaaaa
    71761 aggtataatg atgaaatatg actaaaaaat ttattaaatc agcagtgatt ctaggcttag
    71821 caagcataac catcagcatg acgcaacccg ttgaagccat ttcaaatagc ttagaatatc
    71881 aagcacaata cgaacgtgtc aaagaagaac tagacgcatt aaaagaaaag ggcccaaaat
    71941 taggagaacg ttccctttat tttagattgg tgaataaatt tctaagttgg tttggccaag
    72001 tctgggaccc actcgcaatc aaagaaaccg attacctgtt ggacctcatc ggacaagtca
    72061 attacttggt gagtaacacc gagtttcaag cccctgagta caaagatgct aaaaacaaac
    72121 tagacttagc tgtagcaggc tatgacctct acctagctag agagaaaaaa cgtggtgatg
    72181 ctcctgatta ccaagtgacc cagctaacgc tagaacagct caaaaccatc aaaaagaaga
    72241 tacgagaggc cctcgaaaca tttgcacaag aggtcaaaac aatccagcaa aaaaacccag
    72301 acctatttcc ccatgcttat gttttaaacg ctaagagcaa agatatcaca gataaagcgc
    72361 aacccttttt agtaaatagt tactacgatg tcttttataa gcagttttta ttcactaata
    72421 caaatgacgg gtacaactat aataaagaag cagacaatct gacctcgtat caaaatctga
    72481 ttaaagagct attaggctta aaagctgaga tcgatcagtt aacaaaaggc aagactggcg
    72541 atgaccgttt agagatgtta atgtggcaat caaagttcac cttatctgat tcacggaaaa
    72601 aatcacacct tagcgcctac tatacacaag gcgagtatgt cgataaggtg gtcctatctg
    72661 aagaagctcc caacttgaga acagcaaaag aaaaggtcaa gaccttaaaa gggatcttgc
    72721 atgattacta tgttgaaact aataagccag aaaaagctaa aaagtatcat gtcgaggacg
    72781 agaccttgcc gtctcaacct gaggctcctg ctacacctga agctcctgct cctgctcctg
    72841 ttcctgttcc tggtcaaaaa ccagcagaag atgagagatc gccacaagct acggagccag
    72901 ctaacccgtc aaaagaggat tcctcaacgg acgcatctca gggatctcac gatagtgaaa
    72961 acccagcgac agacagtcct tctcaacctc aggcaccaga ccaaggcaat caccaaagtc
    73021 aagtgcctaa cgccaagcct caaacggaca agacggacac tcctaacgcc ccagccatcc
    73081 cacaggacac cccaaaagcg cctgaggctg gtggtcagag tggccccgct gggaacactg
    73141 aggagaaagc tcctgactct ggacctaaag agtctgatca aagctcatct aaagagtccc
    73201 catccgttgg cgaagacacg acccctaatc agccagatgt ccttgtaggt ggtcaaagtg
    73261 agccaattga tatcaccgaa gacacaatca ctgacgctcc tccgacagta tctgggcaca
    73321 acgcatcaac acagccccaa tctgtggtcg aagacacagc acctcagcgc ccagatgtcc
    73381 ttgtaggtgg tcaaagcgag ccaatcgata tcacccaaga tacccaaccg ggcatgtcag
    73441 gctctaatga cgctaccgtt atcaatgaag atacaaaacc aaaacgcgtc ttccactttg
    73501 acaacaaaga gccacaagca tcagaaaaag cggcagagca aaaacttgct cctcatgata
    73561 gccacacaac ccctcaagct tcagatgata cagcagcccc tcacttgcct gcatctggag
    73621 ataaacctga aaaagtgttt gcacttgctg ccttgacaat ggtcgcagct gcagggctac
    73681 tcagcaaaaa acgtcgcaac accgacaaaa actagtcgct gttaggcaca acgcatcact
    73741 aaggccagtg catttgcact ggccttagtt gggtttttat caaatagagg gtttttcatg
    73801 acaattgtta gcacttcggt gtaaaataaa agtaataacc agcaaaggag caacctatga
    73861 caaagcaaga tcagttaatc gttgaaaaaa tggaacaaac ctatgaggcc tttagcccaa
    73921 agctagcaaa tctcatagaa gccctagatg cctttaaaga gcactatgag gaatatgcca
    73981 cacttagaaa tttttacagt agtgacgaat ggtttcggct tgcaaaccaa ccttgggatg
    74041 atatcccgtg cggtgtccta tctgaagacc tcctctttga tatgatcggt gaccataacc
    74101 aactactagc tgatgtctta gacttggccc ctatcatgta caagcatatg taaccattgt
    74161 taacgtcaca gatactacga tgacaggaca aaaaaagctt gaaaatctca aaaaaaaaca
    74221 gataaaaaac agataatcgt tagaaaaaca gtagatgcgt ctgttaaact aaaggtatca
    74281 aaacaaaagg agcatttcat catgaaattc aaaaaagtat tagtcattcc tgcattagca
    74341 ttagcagcaa catgcttttt aacagcttgt ggcacaaaaa aagattctaa aaaagaagaa
    74401 gttaaagaaa tcaaaatgtc tgacatcaaa gacgacgcag ttagcaaaaa aacaaaagtg
    74461 gttgatggcg aagaagttac agaatacacc acaaaagatg gaaacgtgat tcagattcct
    74521 gcaggaaacg aagaaggcat ggaatcaaaa gatgctggtg gatcaggcgc tcctgctaaa
    74581 aactaagggt tacaacaaag agcataaggt gactcgcaaa cgttacgcat gacatgaggc
    74641 agtctgccta agatggtaac tcacttatca taatgcctaa atagccaaac acactaactc
    74701 gcaaatgtac aaaatcatat acccgtgctt atgtgagcga acggttatat gatttttgtt
    74761 ttccaaaaac aagaaaagaa cgctaaaata gccagtttgt cgtgtttcaa gctaccaaaa
    74821 aggaagtgct aagaagtgct aaaatgaaaa aaagatccat tatacctgtc atcttactgt
    74881 tggtcatcgg attaatcgtt ggtgttaagc gtcatcatga ctagtaggtc ttgctagtga
    74941 ccgttcaaaa gggataacgt tggtatggta taaccataaa aatcgtataa aaagaaaaaa
    75001 tagctattga ggagaaagta tgtttcagtt aagaaaaaaa atgacgcgca aacaattagc
    75061 cttgttgagt gctggagtgt tgacctgtgt ggttggtggt agctacttga taatgaacca
    75121 tcaacaacaa gaaattgtct ctagtgtcaa caaagtaaaa gccttaacca taaaagaagc
    75181 catggaacaa ggaaaagata tcagcttgac cttagctggc gaagtaacag ctaacaacag
    75241 cagcaaagtc aaaatcgact caagtaaagg agaagtcaaa gatgtctttg tcaaaaaagg
    75301 cgatgttgtc aaagtagggc aacccttgtt tagttatgaa acgtcacaac ggttaacggc
    75361 tcaaagttca gaatttgatg ttcaaaccaa agccaatcaa ctccaagttg ctaaaaccaa
    75421 tgcagcattg aagtgggaaa cctacaatcg caaggtcaat gaaatcaata ccctaaaatc
    75481 tcgctacaac actgcaccag atgagagctt actagagcaa attcgcagcg cagaagacag
    75541 tgtatcccaa gcactaagcg atgccaaaac agcagatagc gatgtcaaaa ccgctcaaat
    75601 cgaactcgat aaagctaatg ctactgccac aacggaaaaa ggtaaactag agtatgacac
    75661 tgttaagtca gacactgcag gaaccattgt tagcctaaat actgatttgc caaatcaatc
    75721 aaaatccaaa aaagaaaatg aaacttttat ggaaattatc gacaaatcaa aaatgttagt
    75781 caaaggtaac atcagtgaat ttgaccgtga caagttaaaa atcggtcaaa aagtcgaagt
    75841 gattgaccgc aaagacaact ctaaaaaatg gactggaaaa gtaacccaag ttggcaacct
    75901 caaagcagag gaaaaaggcc aaggtcaagg ccaaggtggc aatgaccaac aagacaatcc
    75961 aaaccaagca aaattccctt atgttatcga acttgaccaa tcagacaagc agccactcat
    76021 tggttcacac acctatgtta atgtgctcaa caatgttcca gaagctggca agatcgtatt
    76081 gaaagaaacc tttacaatgg cagaaaatgg aaaaacctat gtgtggaaag ttgataaaaa
    76141 caaggtcaaa aaacaagaaa tcaagactaa gcccttctca aaaggttatg ttgaggtgac
    76201 aagtggcttg actatgcaag ataagattgc tcagccgctt cctggcatga aagacggtat
    76261 ggaggtagga agtattgtta aaccttaaag atattcgaaa aagctatcat cttgggactg
    76321 aagaatttgc gattttaaaa ggaatcgatt tagaagttaa cgagggtgac tttttagcca
    76381 tcatgggacc atcaggttcg ggaaagtcaa cattgatgaa tatcattggg tgtttagata
    76441 agcctggctc tggctcatat gccattgaag gcagagacgt gtcatcctta tctgataatg
    76501 aacttgctga tttgcgtaat caaaaaatcg gctttgtttt tcaaaacttt aacctgatgc
    76561 ccaagctaac agcttgtcaa aatgtcgaat tgcccttgac ttatatgaat gttcctaaaa
    76621 aagagcgtcg caaacgagcg ctagagatgt taaagctagt aggactagaa gaacgcagtg
    76681 aatttaaacc gatggagcta tctggtgggc aaaaacagcg tgtagcgatt gcaagagctt
    76741 tagtcactaa cccgagtttt atccttggtg atgagccaac aggtgcacta gacacaaaaa
    76801 ccagcgtcca aatcatggac ctatttaaac aattcaatga taacggcaaa acgattatta
    76861 tcatcacaca cgagcctgaa gtagctgcct tatgcaaaaa gacggtgatc ctaagagatg
    76921 gtaatataga acattccgat atagagtaaa gggggaaaat aatggaagat attattgcag
    76981 ctttaagctc tatattatca cacaagatgc ggtcaatttt gacaatgcta gggattatta
    77041 tcggtattgg tgccattatc gcaatctttt caatcatcga aggtaatacc gaaaatacca
    77101 aaagacagtt gattggtggc agcaataaca ctattaacat tgtgtttaac aaaaaaagca
    77161 gtattgaccc taaatttcca gacaagtcaa atgctaaaaa accagactat cttcctttta
    77221 tggctgaaga agagcttagc aaaatacagc aagtcaaagg tgtcaaaaac gccctgatct
    77281 catatggtat tgatgacaaa gtctaccatc taggccaaaa atcatctgca aagatttctg
    77341 ccatcacaaa aaacgtagct gaagtgaggc gcatgacatt tattaaaggc agtgactttt
    77401 cagacaaaga ctttattgac caaaaacagg tgatttacct tgaaaaaagc ttgtatgagt
    77461 cactatttcc aaaagacgat ggccttggaa aatttgtcga agtgatggga aatcccttca
    77521 gggtcattgg ggtgtttgaa tcaaaagaac aaagtggcct cacaagtggg actgagaaaa
    77581 ttgcttatat cccgctacat cagtggtata atattaatgg tgtagtggat gcgacacctg
    77641 agatcacgat ccagacctat cgcgcagatg acctcaaacc tgtagcaaag cgtgtcagtg
    77701 atatgctcaa tcaaacgatc cctaaatcag attatatgtt tggtgtcatg aaccttaaag
    77761 aatttgagcg ccaactagac aacctaaaca aatctaattt tgtgttatta gctggtattg
    77821 ctagcatctc tcttattgta ggtggtattg gtgtgatgaa cattatgcta gtatcagtta
    77881 ccgaaagaac gagagaaatt gggatcaaaa aagcgcttgg cgctagacgt aagcttattt
    77941 taaaacaatt tttaattgaa gcggtcattc taaccttgct aggtggtgtg ataggggtta
    78001 tttcagggat ggtatcagga ttgatcatca caagatcact cgagtatccc tatatcctat
    78061 ccttgttctc agttgtcttg agtttagcgt tttgttgtat tatagggatt gtctttggac
    78121 tattaccagc cattaaagcg tctaagctag acccaattga agcattgcga tttgaataat
    78181 caaccaaaca agcataaaag tcaaaaagga tgaccctttg atgtcatcct tagctgcttg
    78241 atacactaaa cgccaatcta gaaagggaag ttatgtttaa aatattagta gttgaagatg
    78301 atgataccat cagtcaagtg atttgtgagt ttttaaaagc gaataactat gatccagatt
    78361 gtgtatttga tggccaagct gccttagaca agtggcagac aacgtcttat gatctgatta
    78421 ttttagacat catgctccct tccttaagtg gcttagaagt gctaaaaaca attcgaaaga
    78481 catcagatgt ccctattatt atgctaacgg cattagatga cgaatacaca cagcttgtaa
    78541 gcttcaacca tttgattagt gattatgtga ccaaaccatt ttcaccactc attttaatca
    78601 aacgtatcga aaatgtatta cgcgtctcta ctccagatga aaagcgccaa atcggagact
    78661 tacttgttga tgagactgaa catagcgtct attggcaagg aacattggtc aaactaacca
    78721 aaaaagaata tgacattatt gattatttag caaaacgtca ccaaaaaatt gtcaccagag
    78781 accaattgat ggatgacata tggggctatt ctgaactgga tacgcgtgtc cttgacaacc
    78841 acattaagaa ccttcgtaaa aaaatgacgg gtattcccct caagacaatt acaggcatgg
    78901 gctatttatt gggagagcgt gagtgagact aatcaaaaaa acctttttgg tcatcaatgg
    78961 cttaattatt gtagtggtta cctctatttt gttagtgctt tattttgcaa tgccaattta
    79021 ttacaccaaa gtcaaagaca aagaagttaa gcgtgaattt gaccaaacaa gcaagcaaat
    79081 caaaggcaaa acggtaaccg agattagaga tatcctaaca aaaaaaatca acaaagataa
    79141 tatttggtac agcttagtag acagtgataa ccaactgctc tatccttcct tgcagctgtt
    79201 agacggcgtc agtgaaagca aagacagtca aaatgttaat atcgtcacca cctttgacaa
    79261 ctcttattct aatgttaagg tgatgagtca aaaagtaacc ctacgcgatg gaaaaaaaat
    79321 gacattgctt gggcaatctt cacttcaacc cgtaacagat gctagcaaag ttctccttga
    79381 cctctacccg tcactattga tgttttcagt gaccgtaggg agtattgtcg cctacttata
    79441 tagtaggact tctagccggc gtatccttag catgtcacaa accgccaaaa aaatggtcaa
    79501 cctagaacca aacttaacgt gtaccattca cggcaaagat gaaatagcaa tgttggctag
    79561 tgatattaac cgtttgtatg cgagtctttc aacgagtatc aaatccttgc aaaaagagta
    79621 tgaaaaagct tctgattcag aaagagagaa atctgagttt ttacgcatga catcgcacga
    79681 gctaaagaca ccaatcacca gtgttatcgg aatgattgat ggaatgctct ataatgttgg
    79741 tgactttgca gatcgtgaca aatatttgcg aaaatgccga gacgtccttg aagggcaagc
    79801 ccaactggtt caatccattt tatctttatc taagattgaa accctagctt ctcaaaatca
    79861 agaactgttt tcactaaaaa gcagcctaga agaagaaatg gaagtctttc tcgtcttatc
    79921 agaactaaaa catctcaaag tgactatcaa tctcgaagaa caattcgtca aagccaataa
    79981 agtataccta ctaaaggcga ttaaaaatat tattgacaat gcctttcact ataccaaatc
    80041 aggcggccaa gtgatgattc aactaaaaga caaccaacta gtgattaaaa atgaagcaga
    80101 gacattattg acacaacagc agatgaaaca gttattccaa ccgttttatc gaccagatta
    80161 tagtcgtaac aggaaagacg gtggtacagg attggggctg tttatcaccc accagattct
    80221 tgatcagcat catctggctt atcgctttgt tgttcttgat caaagatgga tggtatttac
    80281 gattgatttt ccatcccatc atgacgattg atccacacta gtaggacgac aaaagtcatc
    80341 aatcactaac caagccttga cctttaccca tcattgttta ggcaagtata aaaaagagga
    80401 gagaaatcat atatgaagaa aaggaaattg ttagcagtaa cactattaag taccatactc
    80461 ttaaacagtg cagtgccatt agttgttgct gacacctcct tgcgtaataa cacatcatcc
    80521 actgatcagc ctactacagc agatactgat acggatgacg agagtgaaac agcaaaaaaa
    80581 gacaaaaaaa gcaaggaaac agcgtcgcag cacgacaccc aaaaagacca taagtcatca
    80641 cacactcacc taaccccccc ttcaaatgat actaagcaga ccgatcaggc atcatctgaa
    80701 gctactgaca aaccaaataa agacaaaaac gacaccaagc aaccagacag cagtgatcaa
    80761 tccaccccat ctcccaaaga ccagtcgtct caaaaagagt cacaaaacaa agatggccga
    80821 cctaccccat cacctgatca gcaaaaagat cagacacctg ataaaacacc agaaaaatca
    80881 gctgataaaa cccctgaaaa aggaccagaa aaagcaactg ataaaacacc agaaccaaat
    80941 cgtgacgctc caaaacccat ccaacctcct ttagcagcag ctcctgtctt tgcaccgtgg
    81001 agagaaagtg acaaagacct gagcaagcta aaaccaagca gtcgctcatc agcggcttac
    81061 gtgagacact ggacaggtga ctctgcctac actcacaacc tgttgtcacg ccgttatggg
    81121 attactgctg aacagctaga tggttttttg aacagtctag gtattcacta tgataaagaa
    81181 cgcttaaacg ggaagcgttt attagaatgg gaaaaactaa caggactaga cgttcgagct
    81241 atcgtagcta ttgcaatggc agaaagctca ctaggtactc agggagttgc taaagaaaaa
    81301 ggagccaata tgtttggtta tggcgccttt gacttcaacc caaacaatgc caaaaaatac
    81361 agcgatgagg ttgctattcg tcatatggta gaagacacca tcattgccaa caaaaaccaa
    81421 acctttgaaa gacaagacct caaagcaaaa aaatggtcac taggccaatt ggacaccttg
    81481 attgatggtg gggtttactt tacagataca agtggcagtg ggcaaagacg agcagatatc
    81541 atgatcaaac tcgaccaatg gatagatgat catggaagca cacctgagat tccagaacat
    81601 ctcaagataa cttccgggac acaatttagc gaagtgcctg taggttataa aagaagtcag
    81661 ccacaaaacg ttttgaccta caagtcagag acctacagct ttggccaatg cacttggtac
    81721 gcctataatc gtgtcaaaga gttaggttat caagtcgaca ggtacatggg taacggtggc
    81781 gactggcagc gcaaaccagg ctttgtgacc acccataaac ctaaagtggg ctatgtcgtc
    81841 tcatttgcac caggccaagc aggagcagat gcaacctatg gtcacgttgc tgttgtagag
    81901 caaatcaaag aagatggttc tatcttaatt tcagagtcaa atgttatggg actaggcacc
    81961 atttcctatc ggacgttcac agctgagcag gctcgtttgt tgacctatgt cgtaggggac
    82021 aaactcccaa gaccataacc ccacaaccaa gaagctacct gcctgttgac caatctcaaa
    82081 aagagacagt gtcaacttag aatgaggttc atcagatgat aaagaaagtg accaccccga
    82141 gtcaaaaaat aaaaaaacgt gttcgtaatg gctatctcct aaaactaggt acagcctgtt
    82201 tactcttaag tatactcagt tatggcattg gtcttttggg ccagcctagc atggaaaata
    82261 cgtttatggg aatagcgagt gttgccatgt taggaagtgt ctgtttcttt attatctttg
    82321 ctctaaaccg tatctttgac gcactagagg acaatttgcg agattagagt aataggtcaa
    82381 ataatcttcc aataatttag agcacaagct aagttattgg aagttttttt gtcttttgag
    82441 agccatgatg ccatcaaaaa gtcaaacact ccttatgatg tgagagtcac atgactaaaa
    82501 ttaaaagcaa aatagacccc aaagccctgt tttctcaaaa cagccaacga aaaaagacaa
    82561 gttaaccagt tcataaaaaa catcgtagaa acgttttcaa gagctaatgt tggagtaaat
    82621 tgactgaagt atgatagaat ttttaatgaa tgtgacaata atgtcacaga taaaaaccga
    82681 aaacagcaaa aataattaaa ttgaatataa aaaagttaat t
//
LOCUS       DATWVB010000004        81530 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.004, whole genome shotgun sequence.
ACCESSION   DATWVB010000004 DATWVB010000000
VERSION     DATWVB010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 81530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81530
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.004"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(223..855)
                     /locus_tag="VCX65_000280"
     CDS             complement(223..855)
                     /locus_tag="VCX65_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEP5052774.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDS
                     SWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
     gene            complement(855..1619)
                     /locus_tag="VCX65_000281"
     CDS             complement(855..1619)
                     /locus_tag="VCX65_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEP5052775.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNN
                     TTRTPEMVQSMLANQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            complement(1619..2371)
                     /locus_tag="VCX65_000282"
     CDS             complement(1619..2371)
                     /locus_tag="VCX65_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEP5052776.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGG
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKPHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQITSDGQLNAQAMIEWRAIKQTESETD"
     gene            complement(2381..3511)
                     /locus_tag="VCX65_000283"
     CDS             complement(2381..3511)
                     /locus_tag="VCX65_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEP5052777.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FDSYGIRDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIY
                     ALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGVSFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            complement(3574..4215)
                     /locus_tag="VCX65_000284"
     CDS             complement(3574..4215)
                     /locus_tag="VCX65_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052778.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDI
                     QKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLAD
                     MQENLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSRP"
     gene            complement(4339..5694)
                     /locus_tag="VCX65_000285"
     CDS             complement(4339..5694)
                     /locus_tag="VCX65_000285"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEP5052779.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGS
                     THPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAI
                     ANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
                     N"
     gene            complement(5748..6704)
                     /locus_tag="VCX65_000286"
     CDS             complement(5748..6704)
                     /locus_tag="VCX65_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEP5052780.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVNVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            complement(6701..7552)
                     /locus_tag="VCX65_000287"
     CDS             complement(6701..7552)
                     /locus_tag="VCX65_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEP5052781.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVSLPWYKK
                     ILGGKSK"
     gene            7659..9002
                     /locus_tag="VCX65_000288"
     CDS             7659..9002
                     /locus_tag="VCX65_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEP5052782.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     GRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFICLNCGFKRPQLDYRLTELTAITHQSSEFVIDGQNYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIMEAIEKQESKHAYILATYTAMLEFRSLLADRHVVEKEMN"
     gene            9002..9793
                     /locus_tag="VCX65_000289"
     CDS             9002..9793
                     /locus_tag="VCX65_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEP5052783.1"
                     /translation="MTYTSLKSPENTDYLYDLNIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTSLKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(9906..10895)
                     /locus_tag="VCX65_000290"
     CDS             complement(9906..10895)
                     /locus_tag="VCX65_000290"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEP5052784.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILTKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFECLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            11128..13545
                     /gene="hylA"
                     /locus_tag="VCX65_000291"
     CDS             11128..13545
                     /gene="hylA"
                     /locus_tag="VCX65_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEP5052785.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMGQGTAIYADTLTSNSEPNN
                     TYFQTQMLTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTYLWEHAKDYSASANITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYLY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEANSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSSIEADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     SDTSVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTS
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKHPYHAYVNNQPVDLNNQLVDFTNTKSIFLESDDSAQNIGYYFFKPT
                     TLSISKALQTGKWQNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYEKKATMFSNHNLSHQGFYSFPH
                     PVKQNQQ"
     gene            complement(14218..15981)
                     /gene="lpdA"
                     /locus_tag="VCX65_000292"
     CDS             complement(14218..15981)
                     /gene="lpdA"
                     /locus_tag="VCX65_000292"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEP5052786.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVP
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAI
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            complement(16312..17721)
                     /locus_tag="VCX65_000293"
     CDS             complement(16312..17721)
                     /locus_tag="VCX65_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEP5052787.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKIVRPAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPAVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKG
                     RVHKADVENFKGAQPKASPLARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKP
                     AEAKAPAAKEEKVVDLAEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(17906..18904)
                     /locus_tag="VCX65_000294"
     CDS             complement(17906..18904)
                     /locus_tag="VCX65_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEP5052788.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            complement(18963..19931)
                     /locus_tag="VCX65_000295"
     CDS             complement(18963..19931)
                     /locus_tag="VCX65_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEP5052789.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            complement(20217..22124)
                     /locus_tag="VCX65_000296"
     CDS             complement(20217..22124)
                     /locus_tag="VCX65_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEP5052790.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDKTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQDLTRLMMDYDLLAERFRQQGGFTYEAEIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPHGLDRYVGNYSRFMTLKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAI
                     GYNQHVLSEPINLDVHKLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQETLME
                     EWETIAEQIES"
     gene            complement(22170..22496)
                     /locus_tag="VCX65_000297"
     CDS             complement(22170..22496)
                     /locus_tag="VCX65_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052791.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            complement(22526..23311)
                     /locus_tag="VCX65_000298"
     CDS             complement(22526..23311)
                     /locus_tag="VCX65_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEP5052792.1"
                     /translation="MASIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGN
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADF
                     QAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            complement(23444..25105)
                     /locus_tag="VCX65_000299"
     CDS             complement(23444..25105)
                     /locus_tag="VCX65_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEP5052793.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIVYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            complement(25309..26067)
                     /locus_tag="VCX65_000300"
     CDS             complement(25309..26067)
                     /locus_tag="VCX65_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5052794.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            complement(26064..26933)
                     /locus_tag="VCX65_000301"
     CDS             complement(26064..26933)
                     /locus_tag="VCX65_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5052795.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERYFKGVRLTR"
     gene            complement(27278..28276)
                     /locus_tag="VCX65_000302"
     CDS             complement(27278..28276)
                     /locus_tag="VCX65_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEP5052796.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANRQNITIGIL
                     QFVTHEALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAAASKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKNLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAINREDFPSASFIEN"
     gene            28630..30282
                     /gene="fbp54"
                     /locus_tag="VCX65_000303"
     CDS             28630..30282
                     /gene="fbp54"
                     /locus_tag="VCX65_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HEP5052797.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRVQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSEMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGKTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            complement(30341..31588)
                     /locus_tag="VCX65_000304"
     CDS             complement(30341..31588)
                     /locus_tag="VCX65_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEP5052798.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLV
                     MADLYDMEGLTEVAREKLLQAVSISPEPLVIFGLAEIDMSLQYFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLLYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(31578..32759)
                     /locus_tag="VCX65_000305"
     CDS             complement(31578..32759)
                     /locus_tag="VCX65_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEP5052799.1"
                     /translation="MPLIPDKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            complement(32817..33293)
                     /locus_tag="VCX65_000306"
     CDS             complement(32817..33293)
                     /locus_tag="VCX65_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEP5052800.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY"
     gene            complement(33514..34554)
                     /gene="rfbB"
                     /locus_tag="VCX65_000307"
     CDS             complement(33514..34554)
                     /gene="rfbB"
                     /locus_tag="VCX65_000307"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEP5052801.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKTDAIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(34798..35391)
                     /locus_tag="VCX65_000308"
     CDS             complement(34798..35391)
                     /locus_tag="VCX65_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEP5052802.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(35391..36260)
                     /gene="rfbA"
                     /locus_tag="VCX65_000309"
     CDS             complement(35391..36260)
                     /gene="rfbA"
                     /locus_tag="VCX65_000309"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEP5052803.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHELAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(36319..37425)
                     /locus_tag="VCX65_000310"
     CDS             complement(36319..37425)
                     /locus_tag="VCX65_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEP5052804.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAIKNRKELGDDFKGLIGFDNCLYASGAARVEGAALCETLL
                     KTSGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLMPLGYQVDVRPQKGQ
                     LLDYDVHHIISDNYPVVMPEGEIDLIPFNQGKISVGASHENDKGYDLEPDWQVLEKLE
                     MQALTYLPLLKEATQKSCRVGIRAYTSDYSPFYGQVPGLKNLYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLRSTGKA"
     gene            complement(37465..38253)
                     /locus_tag="VCX65_000311"
     CDS             complement(37465..38253)
                     /locus_tag="VCX65_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEP5052805.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMERDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(38243..38929)
                     /locus_tag="VCX65_000312"
     CDS             complement(38243..38929)
                     /locus_tag="VCX65_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEP5052806.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIT
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(39001..39657)
                     /gene="nth"
                     /locus_tag="VCX65_000313"
     CDS             complement(39001..39657)
                     /gene="nth"
                     /locus_tag="VCX65_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEP5052807.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQNTYGKSKA
                     "
     gene            complement(39654..40337)
                     /locus_tag="VCX65_000314"
     CDS             complement(39654..40337)
                     /locus_tag="VCX65_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEP5052808.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTSQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVTISEDFL
                     SAMNLWSDS"
     gene            complement(40418..40936)
                     /locus_tag="VCX65_000315"
     CDS             complement(40418..40936)
                     /locus_tag="VCX65_000315"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEP5052809.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(41086..43296)
                     /gene="recJ"
                     /locus_tag="VCX65_000316"
     CDS             complement(41086..43296)
                     /gene="recJ"
                     /locus_tag="VCX65_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEP5052810.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYERGIRTE
                     EALDEFLTADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKTWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(43293..44057)
                     /locus_tag="VCX65_000317"
     CDS             complement(43293..44057)
                     /locus_tag="VCX65_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEP5052811.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADM
                     FQVNTLASIHFACLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGTFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(44057..44986)
                     /locus_tag="VCX65_000318"
     CDS             complement(44057..44986)
                     /locus_tag="VCX65_000318"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEP5052812.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(45001..45636)
                     /locus_tag="VCX65_000319"
     CDS             complement(45001..45636)
                     /locus_tag="VCX65_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEP5052813.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFAQREFMIYITQ"
     gene            complement(45629..46867)
                     /gene="hflX"
                     /locus_tag="VCX65_000320"
     CDS             complement(45629..46867)
                     /gene="hflX"
                     /locus_tag="VCX65_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEP5052814.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(46940..47839)
                     /gene="miaA"
                     /locus_tag="VCX65_000321"
     CDS             complement(46940..47839)
                     /gene="miaA"
                     /locus_tag="VCX65_000321"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEP5052815.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLTDIREVTESYSAYDFVQDAQKAISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVDRMLENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            47967..48143
                     /locus_tag="VCX65_000322"
     CDS             47967..48143
                     /locus_tag="VCX65_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEP5052816.1"
                     /translation="MIMEYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(48261..49169)
                     /locus_tag="VCX65_000323"
     CDS             complement(48261..49169)
                     /locus_tag="VCX65_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEP5052817.1"
                     /translation="MKHLKNPPLVMSGLALGTLSFGNLLATYVSIFSYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFLTWWLF
                     FLGNLVLIAYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     ISSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
     gene            complement(49228..49614)
                     /locus_tag="VCX65_000324"
     CDS             complement(49228..49614)
                     /locus_tag="VCX65_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HEP5052818.1"
                     /translation="MLFIAKQTLKSQLIPQDNLLAESRFNEIMDFLTGDFPLVFRPMY
                     NPHRYTISQDNQALEKVKQASYKRMDIAMTHLDGLIGDSGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLAAFMAKMLEM"
     gene            complement(49925..50911)
                     /locus_tag="VCX65_000325"
     CDS             complement(49925..50911)
                     /locus_tag="VCX65_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEP5052819.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQGWAERLEAIGESLPEFVGA"
     gene            51111..51413
                     /locus_tag="VCX65_000326"
     CDS             51111..51413
                     /locus_tag="VCX65_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052820.1"
                     /translation="MTYELCLEYGTYPLSRVYAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            complement(51776..51847)
                     /locus_tag="VCX65_000327"
     tRNA            complement(51776..51847)
                     /locus_tag="VCX65_000327"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51812..51814),aa:Arg,seq:ccg)
     gene            complement(51960..53165)
                     /gene="rpsA"
                     /locus_tag="VCX65_000328"
     CDS             complement(51960..53165)
                     /gene="rpsA"
                     /locus_tag="VCX65_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEP5052821.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
     gene            complement(53292..53363)
                     /locus_tag="VCX65_000329"
     tRNA            complement(53292..53363)
                     /locus_tag="VCX65_000329"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53329..53331),aa:Gln,seq:ttg)
     gene            complement(53414..53494)
                     /locus_tag="VCX65_000330"
     tRNA            complement(53414..53494)
                     /locus_tag="VCX65_000330"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53458..53460),aa:Tyr,seq:gta)
     gene            complement(53555..53785)
                     /locus_tag="VCX65_000331"
     CDS             complement(53555..53785)
                     /locus_tag="VCX65_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEP5052822.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
     gene            complement(53849..54916)
                     /locus_tag="VCX65_000332"
     CDS             complement(53849..54916)
                     /locus_tag="VCX65_000332"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEP5052823.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            complement(54994..57453)
                     /gene="parC"
                     /locus_tag="VCX65_000333"
     CDS             complement(54994..57453)
                     /gene="parC"
                     /locus_tag="VCX65_000333"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEP5052824.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKTDAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            complement(57544..59493)
                     /gene="parE"
                     /locus_tag="VCX65_000334"
     CDS             complement(57544..59493)
                     /gene="parE"
                     /locus_tag="VCX65_000334"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEP5052825.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGSVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDD
                     PIIEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKTEKVSYAWTDGEL
                     EDLRKEFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
     gene            59628..60269
                     /gene="plsY"
                     /locus_tag="VCX65_000335"
     CDS             59628..60269
                     /gene="plsY"
                     /locus_tag="VCX65_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEP5052826.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            complement(60327..61595)
                     /locus_tag="VCX65_000336"
     CDS             complement(60327..61595)
                     /locus_tag="VCX65_000336"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEP5052827.1"
                     /translation="MLLIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAASGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLIVGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(61719..62372)
                     /locus_tag="VCX65_000337"
     CDS             complement(61719..62372)
                     /locus_tag="VCX65_000337"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEP5052828.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGIDWLQ"
     gene            complement(62505..63155)
                     /locus_tag="VCX65_000338"
     CDS             complement(62505..63155)
                     /locus_tag="VCX65_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP5052829.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFLTGLVFGLLLALLGR
                     SHQPLLHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWIIAFLLERYQEFLENKLALV"
     gene            complement(63184..64047)
                     /locus_tag="VCX65_000339"
     CDS             complement(63184..64047)
                     /locus_tag="VCX65_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEP5052830.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWETIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DAQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDK
                     KIPIIDTKDVN"
     gene            complement(64165..65619)
                     /locus_tag="VCX65_000340"
     CDS             complement(64165..65619)
                     /locus_tag="VCX65_000340"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEP5052831.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGKLFAGVPIFLKDLGQELKGDLSTSGSKLFKNHHATKTDLFVK
                     RLEDLGFIILGRSNTPEFGFKNISDSQLHGPVSLPHDNTRNAGGSSGGAAALVSSGIS
                     ALATASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKNSIYQSLQRPLTIAFYQRLSDGSPVSLDTEKALRQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LPMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(65816..66445)
                     /locus_tag="VCX65_000341"
     CDS             complement(65816..66445)
                     /locus_tag="VCX65_000341"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEP5052832.1"
                     /translation="MTLGSQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(66503..67195)
                     /gene="pyrF"
                     /locus_tag="VCX65_000342"
     CDS             complement(66503..67195)
                     /gene="pyrF"
                     /locus_tag="VCX65_000342"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEP5052833.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQG
                     PDIVRSIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEV
                     EAIKAVTPTGFTCLIPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            complement(67472..68008)
                     /locus_tag="VCX65_000343"
     CDS             complement(67472..68008)
                     /locus_tag="VCX65_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052834.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     PAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEE
                     EAFIKYYQSPKVPTGEFE"
     gene            68230..69135
                     /locus_tag="VCX65_000344"
     CDS             68230..69135
                     /locus_tag="VCX65_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP5052835.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLNMDDLRDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHSKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            complement(69214..70002)
                     /locus_tag="VCX65_000345"
     CDS             complement(69214..70002)
                     /locus_tag="VCX65_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEP5052836.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRIIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRREPFYFDDMNAIIKTELGLWRQSIV"
     gene            complement(69995..70708)
                     /gene="deoD"
                     /locus_tag="VCX65_000346"
     CDS             complement(69995..70708)
                     /gene="deoD"
                     /locus_tag="VCX65_000346"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEP5052837.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGRRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVALETLIAND"
     gene            complement(71293..72102)
                     /locus_tag="VCX65_000347"
     CDS             complement(71293..72102)
                     /locus_tag="VCX65_000347"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEP5052838.1"
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTEHIKEDFKGLVKAILAEL"
     gene            complement(72086..72526)
                     /gene="arsC"
                     /locus_tag="VCX65_000348"
     CDS             complement(72086..72526)
                     /gene="arsC"
                     /locus_tag="VCX65_000348"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HEP5052839.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSPYIKEDGEIVNPIEVKGEKDVIDD"
     gene            complement(72542..73753)
                     /locus_tag="VCX65_000349"
     CDS             complement(72542..73753)
                     /locus_tag="VCX65_000349"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEP5052840.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGSRQMETGELIV
                     YTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDIA
                     MIGESFLGHLK"
     gene            complement(73830..74513)
                     /gene="rpiA"
                     /locus_tag="VCX65_000350"
     CDS             complement(73830..74513)
                     /gene="rpiA"
                     /locus_tag="VCX65_000350"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEP5052841.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEVPKAS"
     gene            74891..76990
                     /locus_tag="VCX65_000351"
     CDS             74891..76990
                     /locus_tag="VCX65_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEP5052842.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATTSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKERQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSGFNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVN
                     QTTAKKGISLTIADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILEEGQLVIRQKDQ"
     gene            complement(77048..77791)
                     /locus_tag="VCX65_000352"
     CDS             complement(77048..77791)
                     /locus_tag="VCX65_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052843.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(77939..78538)
                     /locus_tag="VCX65_000353"
     CDS             complement(77939..78538)
                     /locus_tag="VCX65_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEP5052844.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPKDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDNSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(78548..79777)
                     /gene="clpX"
                     /locus_tag="VCX65_000354"
     CDS             complement(78548..79777)
                     /gene="clpX"
                     /locus_tag="VCX65_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEP5052845.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQA
                     LLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            complement(79907..80077)
                     /locus_tag="VCX65_000355"
     CDS             complement(79907..80077)
                     /locus_tag="VCX65_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052846.1"
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNL
                     VNSIHAFYGTLF"
     gene            complement(80097..80594)
                     /locus_tag="VCX65_000356"
     CDS             complement(80097..80594)
                     /locus_tag="VCX65_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEP5052847.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAVL
                     MGRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            complement(80674..81513)
                     /locus_tag="VCX65_000357"
     CDS             complement(80674..81513)
                     /locus_tag="VCX65_000357"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEP5052848.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
BASE COUNT        24687 a        17268 c        14387 g        25188 t
ORIGIN      
        1 tgttttatgg ctgataaatt tctttgaatt tctccttgat tatttgttat aaaagttata
       61 aaataatctt gttggaacca ttcaaaacag catagcaagt taaaataagg ctagtccgtt
      121 atcaacttga aaaagtggca ccgagtcggt gctttttttt gatacttcta ttctactctg
      181 actgcaaact aaaaaacaag cgctttcaaa acgcttgttt tatcattcta catttaggcg
      241 ctgccatctt gctaaaccta ctaagctcca caggatgatt tcgtaaacta tcataaagaa
      301 aaggaaacag tgcaagaaaa agacttctgg aaggatccaa atcacaggat ctttcaaggg
      361 atcaaagagc cagctgctat ctcctacaaa aagcacctga tgaaaaagag taaaaaaatg
      421 ttcaaaccca atgaaactag ccattagacc aatcataaga ggaaacaaag ctgctagtat
      481 taaaggtttt tgaaggagcc agaaacgttt ggtttttaac ctttgtgtga aagtcttaag
      541 ggttgggtaa aggaggccaa gaaaaacgac ttgagttagg tgaaaaagcc acttcacatc
      601 tgcaaaatgc ttgagtccgt ctgctgatga gtgaaaatta gcaaattcca accttgtcac
      661 aaaaggattg gtgaggtaat ttagtagtcc gttatagtta tgcaagatag catccttgct
      721 cataaaaaca acttgttcta actttagatg gtccacctca agaggatacc acagccacgt
      781 tgaatagatc gttatgagaa tagctaacgc taataaccat acccagctac atagtaattt
      841 agtgttttct accatcacaa cctccactca tcaaggctag ataggacatg atctggctga
      901 attggtaagg ttggtacctc ttcaggtctg gtaaagcctg ttgtcacgag gatcgttgca
      961 atatcatttt gaatacctgc catgatatca gtcaagtaat tatcgccaac catgacagcc
     1021 tcagagcgct gaatgcccaa tacctctagt gatttattca taatgatagc gttgggcttg
     1081 ccaataaaaa caggttttac acgtgtggca gcttctagta aggcattcaa tgcacctgct
     1141 cctggcatca aaccacgttc ggttggaatg tttaaatcag gatttgtccc aataaagagg
     1201 gcaccttttt gaatagccaa ggtggctata gccaacatct cataggtcac ctgactgtct
     1261 aaaccaacca ccacgtaagc gggattctca agttcttcta cgtaacctgc tgctgcaata
     1321 gctgatttga gccctgtttc tccaataacg taagctgtct tgccacggtt catgtcattc
     1381 atgtaatcga cggttgccat ggtagccgta taaatggtct caatgcctgt ctcaacatga
     1441 aactgattag ccagcatgct ttgcaccatt tcgggtgttc ttgtggtatt attagtcact
     1501 aataaatagg gaatgcctct ttcttgtagg cgtttgataa accgctcccc tgctggaata
     1561 cggtttttcc cttggtaaat cgttccgtct aaatcaatta aataaccctt ataaggcact
     1621 agtctgtctc gctttctgtt tgtttaatcg ctcgccattc aatcatggct tgggcattca
     1681 gctgcccatc tgaggtgatt tgatggtaag aagttaattg atccaaatgg taactggaag
     1741 taatttgacc gcctggtgag acttctttaa catatttcaa agtcatctta agaggctgat
     1801 gcgtttttaa aaactcacac cccaacacat catacatcca atctaaatat ttactgttgt
     1861 tgacatgacc attcatatca atatcaaaat aacgcacata ataatcacga tcaattgatt
     1921 gttctaaaag aggcatttta ggaacacggt gtggcttttt aacaaaatca gtcttaaaag
     1981 gcgctactaa atcttctgga atagttgcca cttttcgcgt atctgggttt aacaaagcaa
     2041 aataggctaa gatatccact aaaagacccc cctcttgatc ataaatataa aattggcgat
     2101 aacaaaaaaa tttattgtag gagagggctt ttgtttcaat ggtgatggtt tcttgaaaat
     2161 gtggcaagcg atgaatagtg atctcataat ccgttacaat ccaaacaagc ttgtaatcga
     2221 ctaaaaggtt gttgttactt cgtcctaatt gcgcagactg tctaccagaa accatcaaac
     2281 aatagtctaa taaaaggggc aattttatat ctgatttgac atcacataat tcaaaaggaa
     2341 gtgtcaactc ctcctgataa cttaatccca taatactctc ctaatctaat ataaaccgct
     2401 cagcaacaga atcacctaag aaaagaccct ttttagtcat tctgacaaaa gcgtcatctt
     2461 tgacaagcag tccttggttt tgaagctccc taacaatatt tccataacgc tcctcaaaag
     2521 aaacaccaaa tttttcttgg aaccgctgga tggagactcc tgtcttttta cgtaagccca
     2581 aaaagagttc ctcttccatc atttcctctt tgcgcagcac ttcttcattt agtctagcat
     2641 tccctgcttc aaccgcttta agataatgct ggatgggcac ccgattctga taacgaatgc
     2701 cattaaggta acctgaagcc cctgcaccac atccaaaata ctccacatta tcccaataca
     2761 tcaagttatg gcgactttca aaacctggtt tggtaaaatt ggaaatttca taatgctcaa
     2821 aaccattagc ttccatttct gaaataatgt actcaaacat ttccgcttcc aagtcttccg
     2881 ttggtaagtt aagtttacca cgtcgcattt tgttcataaa aacagtgtga tgttccaaaa
     2941 taaggctata aagactaagg tgaggaatat caagtgccag agctttagca acattttcct
     3001 tgacttgatc taaggtttga cctggcaagg cataaattaa atcaatggaa atattgtgaa
     3061 agcctgcagt ttttaaattg gcaatggtgc tataaatttg ttcttcatta tggctacggc
     3121 caatctgctt taattgcttg ttattaaaag tctgcacccc caaggaaatc cgattgacag
     3181 ctgacctctg aagcaccgca attttttctg gcgtcaaatc accaggattt gcctcaattg
     3241 tgaattcttc aagatcatct aaattgaggt ttcgttcaag gtgatttagg agatactcca
     3301 actgtttagc agtgatagct gtaggcgtac ctcctccaat ataaagggtt tttaggtctc
     3361 gaatgccata agagtcaaat tcttgaatca aggctttcaa ataagcatca acaggttgat
     3421 tttggataaa gacttttgaa aaatcgcaat aataacaaat ttgtgtgcaa aaaggaatgt
     3481 gcacataggc tgaagtaggt ttttttgaca tggtcttatt ataccacttt gatgataaaa
     3541 tgtttctatg aataagccat ttcccttgat tcttcatggc ctggaaaaat attttacgag
     3601 ctgacaaacg tcagaatcat tttcgtttcc tggcttgcaa cccttagcta gcaaaacaaa
     3661 tccttgttct tggtaaaaaa gcttgcttga ttcttgactg accataatgc ttaaagaagg
     3721 gaggttctct tgcatatctg ccagaagata tgtctggaca gcctccacaa tagccgctgg
     3781 aacctcgttt tctgtcactg tttcaagaat ccctaaagtc atttctagaa attccccctt
     3841 ttcttgaaga atcacaaagg ctactcttgc tccatttcga agcacttgaa aaagcgtctg
     3901 atcctcgtta acagcagccg caaacacttg attagctgca actgtcgata acaaatgata
     3961 agctaggcct ttatctgcta gcaattgctc tgctgttttt cttgtcacag gcatcacata
     4021 aaaagatggg gtatctagta atcgttcaaa atttttagtt aactgcttga tgcggcgctt
     4081 ttgaatatct tgttttggtg tttgataaac atatgaagca taaccttcct gaaattcagg
     4141 aatcatatct aagtaaagtg tggctgcaaa aggaggcagt aagtccgcta gtttttcgat
     4201 ttgctgtttt gtcatccgat atcctttctc ttctacttta gcaatttata aaaagagact
     4261 tgggctaaac gccccaagcc tctttccaat tgttgacaga agccttagaa ataaggtttc
     4321 ttgtttgtac tcaactcgtt agttatcgca tccgatttct gtacggacga catcagcaat
     4381 agtatcgaca taataatcaa cttcggcatc tgttggcgcc tctgccatga cacgaagaag
     4441 aggttctgta ccacttggtc tcacgagaat acgaccatta ccagccattt catcctccat
     4501 ttttgcaatg atgttcgcaa tagctggaac ttccatagca cggtctttca tgctgttttc
     4561 cacacgaata ttcaccagtt tttgagggta aatggttact tcagcagcta attccgaaag
     4621 tgatttccca gtttccttca tcaccttggc taattggata gctgtcaact gaccatctcc
     4681 agtggtattg tagtccatga taatgacatg gcctgattgt tcaccaccaa gattgtatcc
     4741 tgagctacgc atttcttcaa ccacatagcg gtctccaact gctgtaattg ctttattaat
     4801 accttgttta tctaaagctt tatgaaaacc gaggttagac atcaccgttg tgacaatggt
     4861 attgtgagca agaagccctt tttctgacaa gtatttacca atgataaaca taatacgatc
     4921 accgtcaaca atctcgccag tttcgtccac ggcaatcaga cggtcgctat cgccatcaaa
     4981 ggctaaacca agatctgctc ctgtttcctt aactaactct tgaagttgtt ctggatgcgt
     5041 tgaaccaaca ccgtcattaa tattaagacc atttggtttt tcaccaatga cagcaatttc
     5101 tgcatttaaa tctaaaaaga catcacgtgc tgacactgaa gcagctccat tagcagtgtc
     5161 taaggcaact gtcataccgc ttaagtcagt accagttgtt accaagaact tttcatattt
     5221 acgaagtcct tctggataat ctaccaaggt tccaagtcct tctgcactcg ggcgaggaag
     5281 cgtgtcctcc ggagcatcta agagagcttc aatttccaat tcttggtcat cagctaactt
     5341 aaacccatca ttcccaaaga atttgatgcc attgtcaagc gcagggttat gacttgcaga
     5401 aatcatcaca cctgcacttg ctttttctgt tctaactaaa taagagacac caggtgtcgc
     5461 taaaacgcca agtttataaa cttcaatacc aacagatagt agaccagcaa tcaaggctga
     5521 ctccaacatt tctcctgaaa tacgggtgtc acgcgccaca aaaactttag gtctttcggt
     5581 ctcatgttga cttaaaacat aaccaccgaa tcggcccagt ttaaaagcta actcaggtgt
     5641 cagctcaaca tttgcttcgc cacgaacacc atctgttcca aaatattttc ccataattta
     5701 tataagccta atggcttcct ccattcaatt ttcctagtta ttatccatta ttttttggtg
     5761 gttgtcaact gaacggtcac tactgacggc tcaattgaca cctgactaga agacaaactc
     5821 acggtcttac tagtattttt agtaacatca gaaatgttaa cttctgcaat aatttcatca
     5881 atatcttcta agacctctcg actacctgag ataacagctg tttgttttga caatttgtat
     5941 tgaatatctg ataagctatc atccatcatc cccactgcct caactctaat cgggactgat
     6001 ttcgttattt tttttacagc aactgataaa tttgtttttg caggatcaat tgcacttgct
     6061 aaaatagttc catcagctga gacagcttgt aaggtcactc gactactata attcctatct
     6121 aacacttgat catcaggtaa ctttgccaca acgtgatcaa ttaaagcaat ggtagattca
     6181 tcactggtca cttcaacctt attaaccccc gtttcaattt tgctaatttc ataaccattt
     6241 gcaatttgtt tagcatcaac gcttcctcta acaggaaata ccttagattc ttttttgcca
     6301 attgtgactg atattttatc tggagatacg gtagctgtca ccccagaagg aaggttttct
     6361 actcttaggt tgacatttac tgtacctgga tgactatgtg ttagatccgc cacaatctta
     6421 aaattacgtg tatcattgtt cacttcagaa tctaatttga tacgattagt ggaggttaga
     6481 taaacttccg caccataaga atacccactg ataaaatatt tgtcactatc atacttcata
     6541 tcaattggta catctttaag gctatgcgta taggtttcaa tcgggctata aatttgcgag
     6601 ctagaattat tatgattgct cgatgctgca gttaaaaaaa ggagaatcgc aaaaaagact
     6661 gataccattc ctaaccaagg acgactattt aaaaatcgtt tcatttagat ttccctccta
     6721 gaattttctt ataccatggt aaactaacat ttgaatcact catcaggtag gtcctaagta
     6781 ccgtttcaaa ttcatctgtg cttaaatcat gtaaaaattg gcctttgcga gttactgaaa
     6841 tagctcctgt ttcttctgaa acaatgatag ttagtgcatc agagttttca gataatccaa
     6901 tagccgctct atgacgggtc ccaaattctt tggaaattgc ctttgattct gacaaaggca
     6961 agtaagcaca ggctgccaca atcttattct gaccaacgat aacagctcca tcatgaagcg
     7021 gcgtattcgg aataaaaata ttgatgagta gttgacttga aatgtcggca ttcagcggaa
     7081 ttcctgtcgc aatatattct tgtaaggttt gagtctgttc aatagcaatc aatgcaccta
     7141 tcttgcgtgg acccatatag gccacagatt taatcaaagc atcgaccaaa gcagattcac
     7201 tgctgacgta ctgtttttgt aaaaaaactt gcgtagaacg accaaatttc tccagtcctg
     7261 cccgaatttc aggggtaaaa atgactactc ctgcaattac accataagta atgacttggt
     7321 tcattaagta tgtgattgtc gtaaagccaa tccactctgc aataaaacga agaaccaaaa
     7381 agaaaatgac cccttgaact aaagacatga ttttagttcc agtcaatgct ttaataaaac
     7441 gataaatcaa ataggcaaca attagaatat ctaaaagatg cactgccagc agccaaggat
     7501 ccgcaaataa gcttaataaa aatttaatat cgatactaga taaattattc atacaactct
     7561 catttctata tcaaaaaagt tattagctat attatatcat atcatgatca aagatttttc
     7621 cctatctaaa atcaataaac ttatgataaa atataagcat gaaaatgaag acattactcg
     7681 gcattattgc tggcaaagct gctcaatcca ttttaacaaa actagggcga ggatctactt
     7741 atcctggtcg attggctcta gcttgtaata aagatatttt aaaggatttg tctaaggact
     7801 atgatattgt ggtcgtcact ggtactaatg gtaaaacgtt aacaactgct cttactgtcg
     7861 gtattttgaa agaggcattt ggcgagataa tcacaaatcc aagtggtgcc aatatgatta
     7921 ctggaattac ttctactttt ttagctgcta aaaaagggaa atctggaagg caaattgctg
     7981 ttttagaaat tgacgaagct agtcttccta gaattaccac ttacttaaaa cctagtcttt
     8041 ttgtttatac taatattttt agggatcaga tggaccgcta cggagagatt tatactactt
     8101 atcagatgat tgtagatggt gctcgaaatg ctccaaaagc aactattcta gccaatggag
     8161 atagtcctat tttctcttct aaggacatag ttaatccagt tcagtattat ggttttgata
     8221 ctgctaagca tgctccgcag ctagctcatt acaacacaga agggatttta tgtccaaaat
     8281 gcgaacatat tcttcagtat cgtctcaata cttatgcgaa tctaggagac tttatttgtt
     8341 taaattgtgg cttcaagaga ccacagttgg attatcgatt aactgaactc accgctatta
     8401 ctcaccaaag ttctgaattt gttattgatg gacaaaacta caagataaat gttggtggtc
     8461 tttataatat ttacaatgcg cttgctgcgg tttctgttgc tgaatttttc ggtgtttctc
     8521 ccgagaaaat caaggcgggc tttaacaaaa gtaaggcggt ttttggaaga caagaaactt
     8581 ttactattgg tgataaatca tgcaccctta tccttatcaa gaatcctgtt ggagccagtc
     8641 aagcgcttga aatgattcag ctagctgatt acccatttag cttatctgtg cttttaaatg
     8701 ctaattacgc tgacggcatt gataccagct ggatttggga tgctaatttt gaactcatta
     8761 cccaaatgcc cattacagaa attaatgctg gcggcgtccg tcactctgaa attgccagaa
     8821 gacttagagt cacaggattt gacgacacta agataaaaca agctgaaaag ctcgagcaaa
     8881 tcatggaagc tattgaaaaa caagaaagca aacatgctta tattttagca acctatactg
     8941 caatgttaga attccgtagc ttgctagccg accgccatgt tgttgaaaag gagatgaact
     9001 aatgacttac acttcactaa aatctccaga aaacactgac tacctctatg acctaaacat
     9061 tgctcatctc tacggaaacc tgatgaatac ctacggtgac aatgggaatg tcttgatgct
     9121 caagtatgtc gctgaaaaac ttggagctag ggttactgtt gatattgtat ctatcaatga
     9181 tacctttgaa caagacgatt acgatattgt tttctttggt ggtggtcaag attatgaaca
     9241 aagcattgtt gccaaggatt tgcctagcaa aaaagctgcc ttagcagatt acattgctaa
     9301 taataaagtg gtgcttgcca tctgtggtgg cttccaatta ctagggcaat actatgtcca
     9361 agctaatggg gttaaaattg atggacttgg aattatggga cactacaccc ttaatcagca
     9421 ccaaaatcgc tttattggag atattaaaat tcataatgac gaatttaacg aaacctatta
     9481 tggctttgaa aatcatcaag gacgtacctt cttatctggt gacgaaaagc cacttggacg
     9541 agtggtttat ggcaacggta ataataaaga agaccaaact gaaggtgttc actataaaaa
     9601 cgtctatggt agttatttcc acggtcctat cttatcacgc aatgttaatc ttgcttaccg
     9661 cttagtaaca acatctctta aaaaaaagta tggatcagct atttcactac ctagctatga
     9721 tgatatactg aaacaagaaa tcactgaaga atatgccgac cttaaaagca aagcttcctt
     9781 taataaagtt taagttcttc tttcatgtca tcaaacaaaa actcctaagc aggacacgat
     9841 agatagttcg cttaggagtt ttatagtttt ttcttctgac agagcttctt aagtgattaa
     9901 aaccactaag aaacaatagc tttagcaact tcttcaacgg tcatgcgtga gaagtactgg
     9961 gtcgtatcaa tcgtttttaa acattcaaaa acatcacggt actcatattt acaaccaatt
    10021 aataagttct caatgtcttg cacatctttg atcccaaaga aatcaccata gattttaagg
    10081 tttttaatga tagaattttc aacatttgca aaggttgaaa ttttacctgc agggtaacga
    10141 acattgcgtt caatcgtata ttctggcgct ttgccgtagg tccaatccca actaccaaat
    10201 tgctctttgg cagattgttc aatcttagcc aactcatcct ctgacaagac atattctgtc
    10261 atgtctggat acgtttcttt catcttggtc aagattttat ctgaaaattc ctcaacggta
    10321 attttttctg gtaattcatt taaaatattg gtcacgcgag cacgaacaga cttcactcct
    10381 ttagactcaa tcttatcctt acttacctta agagcatcgc caagaacggt catatccaca
    10441 tcaaacaaaa ggcaaccatg gtgcatcatg cgacctttgt agtaagcttg agcattacca
    10501 cagatttttt tgccatcaat ttcaatatca ttacggcctg taaagttggc tgttacaccc
    10561 aaatcagcta aagtcgcaat cacaggttgt gagaaggttt tgaaatcaaa tgcgccttcc
    10621 gctgttttat ttgaaatgat agtgtagttc aagttattca aatcatgata aaccgcacca
    10681 ccaccagata aacgtcgcac aacatgaata ccatgttcat caatgtattc tttattgatt
    10741 tcttgaatgg tgttttgatg tttgccaata ataatagctg gctcattgat ccaaaggata
    10801 aacaattcgt cttcttccac tagttctcta aaagcatagg cttccaaagc gatgttaaag
    10861 gcaggattgt gacttttgtt aacgatgtat ttcataggag aaaaaatcct ttcaaaaatg
    10921 taatctacct ttctagtata atgaaaacaa atataaaaga caagtgtcct attctgtatg
    10981 acatcttcag tacctacact tattagtgca caaaaactca gccattattt atgtaagggt
    11041 ttataaaaat actttaacgt ggtatatttt tacttagtaa accaatttac ttttattatc
    11101 tcatttttat ataggaggaa tttatcagtg aatacttatt tttgcacaca ccataaacaa
    11161 ttactacttt attcaaacct attccttagc tttgctatga tgggccaagg aactgccatt
    11221 tatgccgata cactgacttc aaattcagaa cctaataata cttactttca aacgcaaatg
    11281 ctcactacta cagatagcga aaaaaaggta gtacagccac aacaaaaaga ctactatact
    11341 gaattgttag accaatggaa cagtattatc gcaggcaacg atgcttatga taaaaccaat
    11401 cctgacatgg tcacttttca taataaagct gaaaaggatg ctcaaaacat tattaaaagc
    11461 tatcaagggc ctgaccacga aaatagaact tacctttggg aacatgcaaa ggattattcc
    11521 gcttctgcta atatcacgaa aacttaccgc aatattgaaa aaatagcaaa acagatcact
    11581 aatcctgagt catgctatta tcaagatagt aaagctattg ctattgtaaa agacggtatg
    11641 gccttcatgt atgaacacgc ttataatcta gatcgtgaaa atcatcaaac aactggaaaa
    11701 gaaaacaaag aaaattggtg ggtttatgaa attggaactc ctcgtgctat taataatacc
    11761 ttatccttga tgtatcttta ttttactcaa gaagaaatcc ttaaatacac agctccaatc
    11821 gaaaaatttg tgcctgaccc tactcgtttt agggttcgcg ctgccaattt ttcacctttt
    11881 gaagccaata gcggaaattt aattgatatg gggcgtgtta aactcatttc cggtattctt
    11941 cgtaaagatg atctcgaaat tagtgataca atcaaagcaa ttgagaaagt tttcacgcta
    12001 gttgacgaag gaaatggttt ttaccaagac ggttctttaa ttgatcacgt ggttactaac
    12061 gctcaaagtc cactttataa aaaaggcatt gcttacactg gagcttacgg taatgttctt
    12121 atagatggct tatcgcaatt aattcctatt attcaaaaaa caaagtcttc tatagaagcg
    12181 gataaaatgg ctactatcta tcattggatt aaccattctt ttttccctat catcgttcgt
    12241 ggagaaatga tggatatgac tcgagggcgt tctatcagtc gttttaatgc tcaatctcat
    12301 gttgctggca ttgaagcact tcgtgctatt ttacgtattg ctgacatgtc tgaagagcct
    12361 caccgtttgg cacttaaaac acgtataaaa acactcgtca cacaagggaa tgctttttac
    12421 aatgtctatg ataatttgaa aacctatcac gatatcaaac ttatgaaaga actgctaagt
    12481 gatacttctg ttccagtcca aaaacttgat agttacgtag ctagtttcaa tagtatggat
    12541 aaattggcac tatataataa taaacacgat tttgcttttg gcctatcaat gttttcgaat
    12601 cgaactcaaa attatgaagc tatgaataat gaaaatcttc atggctggtt tacttctgat
    12661 ggaatgtttt acctatacaa taacgattta ggacactaca gtgaaaacta ttgggcaact
    12721 gtaaatccct accgcttacc tggaaccaca gaaactgagc aaaaaccact agagggaact
    12781 cctgagaata ttaaaacgaa ctatcaacaa gttggcatga ctagtctctc tgatgacgct
    12841 tttgttgcaa gtaaaaaact taataacaca agtgctctag ctgctatgac cttcactaat
    12901 tggaataaaa gcctcactct caataaaggg tggtttatct taggaaacaa aataatcttt
    12961 gttggtagca atatcaaaaa ccaatcatct cacaaggcgt atacaactat tgaacaacga
    13021 aaagaaaatc aaaagcaccc ttaccatgct tatgttaaca atcaacccgt tgacttgaat
    13081 aatcagctag ttgattttac aaacactaaa agtattttcc ttgaaagtga tgattctgct
    13141 caaaatattg gttactactt cttcaagcca acaacactta gcataagtaa ggcacttcaa
    13201 acagggaaat ggcaaaacat aaaagctgat gacaaatcac cagaagccat caaagaagtt
    13261 tcaaatacct ttatcactat catgcaaaac catactcaag atggcgatcg ttatgcctat
    13321 atgatgcttc caaatatgac tcgtcaagaa tttgaaacct atattagcaa gcttgatatc
    13381 gacttgttag aaaacaatga caaactggcc gctgtctacg atcatgatag tcaacagatg
    13441 cacgtcattc actatgaaaa aaaagcaacg atgttttcaa atcataatct ttctcatcaa
    13501 ggcttttata gttttcctca tcctgtcaag caaaatcaac aataaaagct tgctcatcaa
    13561 ggaattgcag ctaaaaacaa tgctcttaac tctcataaaa ttccccacaa aagacaacga
    13621 cgcttaccgc atactgggta tcagtcctcc tctttagaat tcttaggtgg agctttagtt
    13681 gcttctttta accatatcac aaaacccttt cgtaagaaag acttaaggat ttagctgtta
    13741 ttggaaagta agggttaaca atgaaacgtt attaaagaca aaaaactgga aactgcactg
    13801 agccccaaaa gttggctact ctatttgaag taaaggattt agttctgtat tgtagaggac
    13861 taagtccttt tcgttttatt ttgatacggt tattggtgca ataatcgatg ataatagtag
    13921 gtagaacgag tcactttagc cgtccttaaa agaaaatcta atcagagctc gtctttgtcc
    13981 attctttata atggtttttt gtcttcttct tttcagagat gcttctttca aacggagttc
    14041 tctcgttttt ttagcgctaa atgtctagct tatcttcata gcttaatgtc atacaaaaac
    14101 accccaaacg ttagggtttt atatctaacg tttggggtgc agttcatagt tgtgctagtc
    14161 ttttttgtga tctgttatgt gatgatattt ttcattagtt aataagacaa agacgtttta
    14221 cttacgtttt ggtgggttat ggatagcttc gccaagcaca tctgcaaagg cttcgtacat
    14281 cacttcagag aaggttgggt gtccatgaat tgataataac aattcatcaa cggttaattc
    14341 agattccata atagtagctg cttcgttaat catctcagct gcagctggac caataatatg
    14401 aacacctaag atttcgtggt atttggcatc agcaataact ttaacaaaac catgggcttc
    14461 atttgaagca atcgcacgtc cattaccagt aaagctgttt ttaccaataa gcacatcacc
    14521 atattgttca cgcgcttgtt cttcagttaa accaaccatt gccacttcag ggtgtgtgta
    14581 aacggctgct ggagtgtatt taaggttagc tttacgagtt gtgttgccat gtatcgcatt
    14641 ttctgcagcc acttcaccca tacggtaagc agcgtgagca agcattttcg ttccgttaac
    14701 gtcacctggc gcatagatac ctggaattga tgtctcttgg tagtcattaa ctttgatacg
    14761 gttacgatcc atttcaaggt taagattttc cagaccgttc atttgtggta cacgaccgat
    14821 agaaagaaga gctttttcag cgacaacttc ttcaccattg ttaagtttca aggtcaattg
    14881 gttatttgct tcaacaattt cagagacacc aacagatgtt ttgatcttca tgcctttctt
    14941 agaaaggatt ttttgaagtt caagagagac ttccttatcc atagctggga taatgcggtc
    15001 agccatttca ataacggtaa catccacacc gtaagatgcc caaacaagtc caagctcgat
    15061 accaacaaca ccaccgccca taactgctag tgattttggc atttcacgga ggtcaaggat
    15121 atcgtcagac gttaagacaa gtttagagtc aattcctggg atattgatac gtgatacttt
    15181 agaacctgta gcaaggataa cgttgcgacc cttaatggtt tgtgacccaa tggttacagt
    15241 cttgtcaggg ttaacttgac caagcccatt aaagatagtg actttattag cttttagaag
    15301 accttgaacg ccgcctgtta aggttttaac aacggtgttt ttaaagtcaa ctgttttgtc
    15361 catgtcaatg gtatagttag ttgaggcaag gttaatccca cgtcctgctg caatcttaat
    15421 accatcaagg atttcagcat ttttaaggta agttttggtt gggatacacc ctacgttcaa
    15481 gcaagttcca ccaaattcag atttctcaac gatggcaatt ttaccaccaa gttgagcacc
    15541 acgaatagct gcataataac cagcagggcc accaccaaca acgatgatgt catactcatc
    15601 atcagcaagt gcagcttttg gtgcagctga agcagcttga gctggtgctt ttggcacttc
    15661 aagtccagca gcttctaaat cttctgttgt acgagcaaca ttcacatctg aagcagctgg
    15721 gctagaaacc tcaacagatt caccttcagc accgatatat ccgataactt ctgttacagg
    15781 tactgtttca cctgcttgac gtgtaatttt aagaagaaca cctgagtctt ctgcttcaag
    15841 ttccatattg gttttatctg acatgatttc aagaagaata tcgccttcat tgacagtatc
    15901 accttcttgt tttttccact cgatgatttc accttcttgc atgtcaacac cgagttttgg
    15961 cataataatt tcaacagcca taatttaaga taccaagagc aaggagaaag cgattgaatt
    16021 tttgcggtaa gtcagaaatc tttgatttcg ttgacgcacc cacgtcagga cgactaggac
    16081 tttccgaaac aaaaattgag gaaagttcag acgtctacga cgctaagatt agccaactct
    16141 taccattttt atccgagctt ttcgctcgga ttcaattgct tatcactcat ttgcatgaga
    16201 tctcctcgtt ctacatcctt tctatatttt tgagaaaagg gcacccacca agtctaaact
    16261 tagcaaaatc ccttttatta ttgaatgctt ttcttgttta aaactgattg atcagattaa
    16321 caattcaaat ggattttcca tcaatttctt gagatcaacc atgaattttg caccgttcat
    16381 accatcaact aaacggtggt cgatggttag gcacattgcc ataattggac gggcaacaat
    16441 ctcaccatcc acaaccgttg gagttgggat agttgctcca acaccaagaa ttgctgagtt
    16501 tggttggtta ataattgggt taaatgtctt cgtaccaaac attcccaagt ttgtgataga
    16561 gaaggttgat ccagacattt cagctgcttt caacttacca gtttgcgctt ttttaatcac
    16621 atcttttgaa gcaagcacaa aatctgacaa gctcatcttg tcagccccat ggataacagg
    16681 aacgataaga ccatcatcaa gacctacggc aataccaagg ttcacaaagc ggtgtaattc
    16741 aatatcatta gcatcattga tgagggaagc attcatgtac tcatgctcag gtttcatcaa
    16801 ggttttaacc actgccatac caatcaagtc tgtgaagctg actttaaggc ctgttttagc
    16861 catgattggg tcaattaact tcttacgaag ggcaatcatc tctgtcatgt caatatcgta
    16921 gttaagcgta aaggtaggag cagtaaggta agagtttgtc atacctttag agattgcctt
    16981 acgcatagct gacattggct tgtgttccac accttctgca agatcaacaa ctttttcttc
    17041 tttagctgct ggggcttttg cttcagctgg tttagccgct tcaagaatag ccatgatatc
    17101 ttctttcatg accttaccgt taaagccagt acctgatacg gttgccaaat caataccttt
    17161 gtctgctgca attttacgag caagtggtga agctttcggt tgagcacctt taaagttttc
    17221 aacgtctgct ttatggacac gtccttttgg tcctgttcct ggaacttggc caaggtcaat
    17281 gcccatttct gctgctgcct tacgtgcagc tggagtagca cgaacttttc cgccatttcc
    17341 ttgcggaata gctgtcgctg ccacttgagg agctggactt gccacatttt cttttggagc
    17401 aactgctggt ccagcgtctg ctgaagcagg aactggaatt tctgttgttt tttcacttga
    17461 agcaatagta tctactgatt caccctctgc accaatgtaa ccgataactt cagttacagg
    17521 tacagtatca ccagctggac ggacaatttt caatagcaca cctgagtctt ctgcctcaag
    17581 ttccatattg gttttgtctg acatgatttc aagaaggata tcaccttcat tgacggtatc
    17641 accttcttgt tttttccact cgatgatctc gccttcttgc atgtcaacgc ccagctttgg
    17701 cataataatt tcaaatgcca tttctacatc ctttcacgat ttgataagcg ccatcaacat
    17761 ccccaccttg ctacgaaaac atacgaaagg tgaggtgccg cgacacggga taagacaact
    17821 cagttcttct aaaaactttc aaaatagttt ttagctgaga cgttactgat aaacatagcc
    17881 tttatcagac cacttgcctt atcttctagt tgcctttgtt tgccattttc acaatggcag
    17941 ctttgatttt ctcaacgtct ggtaagatcg cttgttcaag tacacgtgca taaggtactg
    18001 gaacatcttc acttgcaaga cgaacgattg ggtgatcaag gtaatcaaag gcttcacttt
    18061 cagtaatcat ggttgcaatt tccccaatga atccaccggt cttgtaggca tcgttgacaa
    18121 gcatcaattt acctgttttc ttaacagatt caataatcaa ctctttatca agtgggatga
    18181 gggtacgtgg gtcaacaact tcaacgttaa taccatccgc tgcaacttct tcagccgctt
    18241 gaaggacacg ctccaacata cgaccatatg acacaattgt caaatcagtt ccttcacgtt
    18301 tgatgtcacc tttgccaagt gggatataga agtcaggatc ttggttaact tcttcttttt
    18361 taccataaag cgcttttggt tccatgaaaa gaacaatgtt attatcacgg atagctgatt
    18421 ttaataagcc tttagcatcg ttggcattac caggagcaac aactttgatt cctggaatgt
    18481 gagtcaacca tgcttcaaga gattgtgagt gttgcgcagc ggaaccaata ccagaacctg
    18541 atgccacacg gaaggttaca ggggtaataa ggcctccacc gaacatgtaa ttatttttag
    18601 caccattatt cacgatagcg tccatcatga tggtaaggaa atccataaag gtaacgtcga
    18661 caattggacg tagtcctgta atagctgcac caatagccgc accagagata gcagcttctg
    18721 aaattggggt atctttaaca cgtttaggac caaattcttc aatcattcca acagaagtcc
    18781 cgaagtctcc tccgtaaacc cctacgtctt ctcccataag gaaaatgttt tcgtccttgc
    18841 gcatttcctc agtcatagca aggttgactg cttcacgcaa agccattaat tttgtttctg
    18901 acatcatttt tatttctcca tttattattc aaatacgatt gcttcttact gacaaggtga
    18961 tcttagtcaa cccaaacgtc ttcgaaggct actgaaagtt ctggatctgg actgttttgt
    19021 gcaaattcat aagcatcgtc aacttctttt ttgacttgtg cttgaatagc atccaattcg
    19081 tcatcagtgg caatgccttc gcttgtcaga taagtacgat atttgatcat tggatctttt
    19141 tctttccact catccacttc ttctttagta cggtatttac cagcatctgc agtcgagtga
    19201 ccaaaccaac ggtatgattc tacctcaaca atagctggac catttccacc acgaacatgt
    19261 tcaacggctt tgcccattgt ttcatagaca gccatcacgt cattgccatc ttcacagtag
    19321 aaaccaggaa ttccgtaagc ttctgcacgt gtgtataaat gtggtgtatt tgttgcatta
    19381 ttgatgctca ttgaaattcc ataacggttg ttgatgatga agaaaataac aggaagtttc
    19441 catgttgcag ccatattaac agactcgtgg aatgatcctt cgttagtagc gccatcacct
    19501 gagaaagcaa cagctatatt gttagttcct ttgtattgtt gggtgagggc agcaccaact
    19561 gcaagagcgt aaccaccacc aacgatacca ttggtaccat agtttccttt ttcaaaatca
    19621 gccaagtgca ttgagccacc acgcccttta gaaacaccag tcgctttacc agcaagctca
    19681 gccatcattt tattaaggtc catgtcttta gcgattgatt gtccatgtcc acggtgattt
    19741 gaaaaaataa tgtcatcgta agacaagtga gccaccgctc caacattggc tgcttcttca
    19801 ccaactgaga agtgagtcat gccttgtaca aatccacgac ggacgagttt attaatacgt
    19861 gaatcaaatt cacgaatacg ttccatttta aggaacatat ccaaatgttg ttctttagaa
    19921 actgttacca tttcggcctc catattatca tattaccttt ttatgataaa actttttttc
    19981 acaatttgca aataattaaa tcgctttcta ccttacctta tttggttttt tagaaatgca
    20041 atagtttgtg aaattacaaa caaaactgta ctaaaaaatt taaaaatact atataacagt
    20101 ttcacgtttt accgaccttg acataaaaaa acacatcatt ttaaaacctc tttcacacct
    20161 tcaaacaagt aacaaagcga taaaaataag cttagcaaaa ctgctaaagc ttatttttat
    20221 gattctattt gttcagcgat ggtttcccat tcttccataa gagtttcttg ttcttgatcc
    20281 aattggtccc attccttttg ccaagcgatt aactgcgccg tatcattgga ggcatgcatg
    20341 tcttcttgaa tagcaccaat gcgctcttca atggtttcaa gtcttgcttc aatctcctca
    20401 tatcggcggg tcaagcgacg acgctctttt tgattagctt tttgtagctg ataatcagtg
    20461 gcagaggctt cttttgtttc ctcaactgtc tctcctgctg ctaggcgggc tagttcttct
    20521 agctctgcct ttttctcaag gtaataatca tagtcaccta agtaaagggt tgagccattt
    20581 tcggtaattt ccagaacctt agttgccaaa cgattaatga aatagcggtc gtggctgaca
    20641 aaaagcaagg taccgtcaaa gtcaatgagg gcattctcta gcacttcttt actgtcaatg
    20701 tctaggtggt tagtcggctc gtccagaaca agaaaattat tgttttccat agataacttc
    20761 gcaagaagca gacgggcttt ttctccacct gacagcatag ccaccgattt tttgacatca
    20821 tctccagaaa agagaaaagc ccctaatcgg tttctgatat cgacttctgg cgtagttgaa
    20881 aaatcctgcc ataattcttc caaaactgtg ttgctagacg tcaaatgtga ttgggtttgg
    20941 tcatagtaac ctatttcaac attggcaccg tatttcactt ctcctttgat gaaaggaatc
    21001 tgtccaataa cagatttaat cagagtagat ttaccaatac catttggacc aacaatagca
    21061 atcgcatcta atttgtgaac gtctaggtta ataggctcag ataaaacatg ttggttataa
    21121 ccaatagcag ctttttcaac cgtcaacacc acattgccag acggcttatc tgcctgaaaa
    21181 gtcatgtgag ctgattttct agcactagtc ggtttgtcta agcgttctat tttttccaat
    21241 tgcttacgtc tcgcttgagc acgttttgta gttgaagccc tgacaatatt tttttgaaca
    21301 aaatcttcta acttggcaat ttctttttgc tgtttgtcaa actgcttttc ttcggctact
    21361 aatttttcag cttttaaggt cataaaacga gaataattgc caacgtagcg atccaatcca
    21421 tgaggagtta aatccaaggt cactgttgcc accttatcca aaaaataacg gtcgtgactc
    21481 acaatgatta gagctccttg ataattggcc aagtagttct ctaaccaggc aatggtttca
    21541 atatctaagt ggtttgttgg ctcatcaagg accaatagtt ctggcttttc taaaagcatt
    21601 ttagccaagg ccagacgagt gttttgaccc cctgacagct cagcgatagt catctgccac
    21661 atgctttcat caaatttaaa gccatttaaa atggctttaa tctcagcttc atatgtaaag
    21721 ccaccttgct gacgaaaacg ttctgctaaa agatcataat ccatcatcag ccgtgtcaag
    21781 tcctgacctg aaacggttgc catatccatt tccatctgac ggagacgctt ttcatcttgg
    21841 cgtaatgctt cgaaaacctt gagcatttcc tcatatatcg ttttgtcaga ttcaaaacgg
    21901 ctattttgag ccagataaga caaggttagg tcttttttag tattaacttc tccgctcgtt
    21961 ggggtttctt ccccaaccaa tagcttgagt aaggttgact taccagctcc atttggcccc
    22021 actaatgcaa ttctgtctct ttcatcaact tgcagtgata tgttttgaaa aagaacatct
    22081 cctgagaaag agcgttctaa cttgtttcct tgtaaaataa tcatactttc attctaacaa
    22141 aaaaatgccc ttttgaggac attttcagcc tagtttccaa aagaaatcga actcttttta
    22201 agtcgttgat taccttcttt agcgctaaca aggaaagtgg aatgactatt accactccca
    22261 tgacgcgtct ttgcagatgg cttttgtgtt aagatatcaa aaatttgcac cacttgctca
    22321 gtaactatcg agatcttatt ggctaaaacg gaatcactgt gattagaata gtacatcagc
    22381 cctataataa taatcgttac taataagata gtttgtaaaa accctttgat aagatgccaa
    22441 aacattttca ctattagctt aggcagccac aatatgatcg ccagtaattg tttcatttgt
    22501 cacctcatgt tgtactagga aatggttaag acaacctttc ttctttttgg tagtttatcg
    22561 gtaaccactc taacaggact tctaattgct ggttccaata gtaccactca tgtttaccat
    22621 gacctttatg ataatcaatg tcaagacctt gagcctgaaa atcagcaata gctttttcat
    22681 tagtggcaaa aagaaaatcc tcatagccac accaagcata aaatttggtt tttccatcac
    22741 tttctgccac catattttta aggtaatgct tgtcaaggtc agggtcatca aactggccaa
    22801 aaacgccctg ccaataggct aattctccca ggtttccctc aagcaaggtc tcaggagaaa
    22861 aatccaaagc gcctgaaaac gatgccgcat aagaaaaccg attgcttttg agtgcccact
    22921 taaaggcacc atagccaccc atagagagcc cagcaacaaa ggttttttct cgtttctggg
    22981 tcatattagg aaagaaagct gctaagacct gcggtaactc ttgtgacaac gcccgataat
    23041 agttaagtcc ataagccgtg tctgtatacc aacctaggtc tgtcgaaggc ataacgacta
    23101 tcaaattggt atgccgcaac aagcgttcaa tagctgttcg tttttgccaa gagttttcat
    23161 tgcctcccat accatgtaac aaatataaaa caggaatatc cttatcccct tgatcttttt
    23221 tagggatttc agactggtca ggataaatca catttacctt acgctccatt cctaaaacta
    23281 ccgaatggta ttcaattgca atacttgcca ttcattacac tcctttatac caaaataatc
    23341 caatcacgta aatctactgt atttttgggt gaacagtttc ctggtttacc agttgttaaa
    23401 atcaaagaag gtaggcagtt tttgcctaac cttcctattt tcactaacga acttccatca
    23461 caaccggcag aatcgctggg cgccttttgg tttgttcaaa taagaattta gacaaatcat
    23521 ctctgacatt cccttttaat tcgccccagt caaaggtatc tttttttaag taattgccaa
    23581 cagttgtatt aactaattct gcactttctc ttaaaatatc atgacttttc ttgacataca
    23641 caaatccacg cgtattaact ttagccttag aaataatgcg tttttctttt ttagaaacag
    23701 taatagcaac aatgaaaata ccatcttctg acaagacttt acggtctcgt aaaacgatat
    23761 tacccacatc accgatagca ttaccgtcaa tcatgacatc actggcaggt acacctcctt
    23821 catggagaaa accttcgtca ttaagcacca tgatatcgcc acgcttcaga atatgaatat
    23881 tctctggaaa aataccaact tcttcagcta gctttgcatg ggcagctaaa tcacgatatt
    23941 ctccttgcac tggaaaaaga tactggggtt ttaacaaatt catcaatagt tgcaaatcac
    24001 gcccattagc atggcctgac acgcgtaagt tttgagtgat taatttaaca gaaccaccgg
    24061 ccttgtaaat caagttttct acacgcgcca ccatagcttc tttagccgta cttggtgtag
    24121 ttacaatata aacaaggtct ccttctttga tttgaacata acggtgacgt cccgctgcca
    24181 ttttttgtaa gctattaatt ggctcaccca tacgaccagc ttcaaggatg attaattcat
    24241 ggtcttcgaa tttagacata tccttaggtt taattaaaag acgctcatcc gtaatcatta
    24301 atttttctag acgtaaagct gttctgacaa tattttctgc atctgttccg gttaaaacaa
    24361 cacgacgccc atgggcagtg gcggaatcaa atacttgctg aatccgaaca agatttgagg
    24421 ctactgcagc tacaatgaca cggccatcag catcagagat aacactgtcc atttcttcac
    24481 caacttcaga ttcgctggca atctgatcgt tgcttgtcgc attgactgaa tctgataaaa
    24541 gagctagaac cccttctttc ccaatctcag ctaaacgtag caaatccgtc tgataacctt
    24601 ctcttgctgc ttgatcaaat ttgaagtcac cggtataaac aatgtttcct ttatctgttc
    24661 caataacaat acccatactt tctgggattg aatgcgttgt tctaaagaac gaaactaggc
    24721 catctttaaa ttcaatttca gtatcactgt ctaccacatg aaaattatta aatttcttag
    24781 tgctgttatt acttttcaca aatagcttgg ctaattcaat agtcaattca gatccaaata
    24841 caggagctga tacttcagct aacaaataag gaagggctcc aatggcgtca gcatggccat
    24901 gactcaagaa aatcccttgt actttacctt tgttttcaat tacataatct aaattgggga
    24961 tgactaaatc taccccaagt tgctcatttt cagggtactt gagccctgcg tctaaaataa
    25021 acatagaatc gttaatttct accaaataga agttttttcc gtattcacgg acccctccca
    25081 aggcaatcat tttaatatca gtcatgatac tcctttaaat attttattat tacaaacggt
    25141 ccttacaacg taagtcgaat tactgttatg tagctatgct actatcttct atagtatatc
    25201 atatttgagg cgttttttct ctaaatagcc ttgatacttt cagattattt tcagtatgga
    25261 aatcaaaaaa tcactgactt attattagtc aatgatttag atcgttgatt agtcaaatag
    25321 ttggtaatag tcagtaatcg tcagttgttc tttttccatt tgatttaaat ctttaataat
    25381 gtttccatct ttcattacaa tcagacgatt cccataagtt aatgcatctt ccatatggtg
    25441 ggtaatcatc aaagctgtta agccatcttt tgtcacaaac tcatctgtca attgcattaa
    25501 agattgactc gtcttagggt caagggcagc cgtatgttca tctaataata agagagctgg
    25561 ctttttcaac gttgccatta ataaacttaa agcctgtctt tgtccaccag acaaaagacc
    25621 tgctggtgtt tctaaatgct tttctaggcc atttcctgtt cgtttaacca aatcctcaaa
    25681 actagctaag tgctctgtta tttttcgaga agccaaggag cgtttttctc ctctttgacg
    25741 tgcgattaag agattttcag ccactgtcat ccgaggggct gttcccattt tgggatcttg
    25801 aaagactcgc gataggtaaa gagctctttt ttctgccggc caatgcgtca catcctgacc
    25861 aagaatccta atttgccccc gtgtcaaact tagcgttcct gcaattacat taaaaagggt
    25921 tgattttcca gctccatttc ctcctaaaat agttaaaaaa tcatgttcat agatagttag
    25981 tgtcacattg tccagtattg ttttagcatc ttcaaaacca ttatctacgt caactgttgc
    26041 attgatcaat tcaataattt ttgtcatcgt gttaacctca ctcccttaaa gtagcgctct
    26101 tttaccactg gtatcatgag gcacagtgct aaaacaagag cactaattaa tttcaaataa
    26161 cttgtattaa aacctagcgt aataactact gaaattaaaa attgataaag aatcgagcct
    26221 attacaatag caatcaaacg ttctaaaaga gtcagtccag ttgagtatag tacttcacca
    26281 acaattatgc tcgccaaacc aataacaata actccaatcc cttttgagac atctgcatag
    26341 ccatcttgtt ggctcactag agcacctgat aaagctatta aactattaga aaccacaagt
    26401 cccataactt ccatccaatc cgtgttaata ccaaaactct tagccatatc tttattgtct
    26461 cccgtagcga tataagcttg acctagatta gtgtaaagga aatagatcaa aacgctaata
    26521 acaatcacaa cagttatcag acctgttaaa aggctattta aatcaattga aaaaggtaaa
    26581 caatcctgaa tacgtttatg atcatgtaaa cccaagtttg ctcttcccat taccattagc
    26641 ataatggagt tacatgacgt catcaccaaa attccagcta aaagtgttgg catttttcct
    26701 ttcgtatata acagccctgt taaaaaacct gctaaagcac ctgataacat accaagtaag
    26761 gttgatagaa atggattcca ccctaagcta atagcggtga ccgcaacagc tcctcctaaa
    26821 ggaaaagaac cttctgtagt catgtcaggg aagtttaaaa tcctaaaggt caggtagatt
    26881 cctaatccta aaactcccca tataaggcct tgtgaaactg atgaaataat catatttttc
    26941 ctcatattta tattagcggg taactctcgc cagtataaac cctttcttta cattaatttt
    27001 tagatttgtt ttatacttag ttcagcaccg tggcttagtc ttttttccaa tcactttaac
    27061 gaaactaaga cagaaaacaa aaaaatcgag aatcatgttt aaacttactc aaaaggcaag
    27121 attttttacg tgtctgaaat agagcatttt aaaactaaaa atgataaaaa taacccttac
    27181 atcctcaaga cgattgtctg acttggcatc caaattcatc tcagtgaggg tgttttttat
    27241 ggttttttct tgacctttta tatcacatgt cattgtatta attctcaata aaagaagctg
    27301 aaggaaaatc ttccctgtta atagcaatac ctaattctgc tgctacattc ttattaatta
    27361 gcggttgacc aatatccaca actttgacag gaacatctac aacacgcttt cctttgatta
    27421 attttaacac ctgattagct gtttgaactc ccaaatcgta ctgattttga gaaatggctg
    27481 ccaaaccacc tttttcaacc attcgatcaa cgctagtgta gacaggaatc tttgcagcct
    27541 tactggttgt catgactgat gaaaatgcac ttgctatagt attgtcttgg gggataaata
    27601 ccgcgtctac tttacctaac ataactgaca tcgtggcagg aacttcgtta gtagaaggaa
    27661 ccgcgtatga aataacttga tagccctttt tgcgagctaa ccgcctaaac tctttaactt
    27721 gagataagga attatcctca ttacttgcat ataaaattcc aactgttttg acatgtggtg
    27781 tcagattttt cattaaatca attgtctgtt taacaggcac tttattagat agaccagtta
    27841 cattagcttc aggttgatcc aattgcatca ctaatctaga tcctactgga tcagatactg
    27901 ctgacatgac aactgggata tccttgctgg cagctgctaa gccttgcgcc gccggggttg
    27961 cgataccaat cacgatatca cttcctgatt gcactaattg cctactcatt gtttggattt
    28021 tactctgatc cccctcagca ttcataacct taatcactac attttgtttt tgaggcatct
    28081 gctttttgag ttgatcttca atacctcgct taatatcatc aagagcctca tgagtaacga
    28141 attgtaagat accaattgta atgttttgtc ggttagccaa atcacggttt tcctttgata
    28201 ctccttttga taatagagag cctatcacta ttacagttaa aacaaggagg gtagctatta
    28261 aactcttgtt tttcatctga attcctcaca tttcatgtca atctctttaa aacgttgatg
    28321 atgagaatac ttctcaaaag aaaaagcact tagtaatgat tactaggcgc ccttgtgaaa
    28381 tccaatgtca gcgcatagat atctttttag aagtactcta aaagtcgtat ctatgccaat
    28441 tcataaacac aacttatcta tgccagcctt gccaatttac taagtgttgt gtttttacca
    28501 tcattgactt cctttctcgt ttttttaaca ttataaccta aatcaaaaaa attgcaagct
    28561 ctttcgtcca tatttttagt caagtatttg tggtataatg aagagattag aattcagaaa
    28621 ggagaaacca tgtcttttga cggctttttc ttacaccatt taaccaacga attaaaagag
    28681 aacttgcttt acggtcgtat ccaaaaggtc aatcaaccct ttgaacggga acttgtctta
    28741 accattcgta accatcgcaa gaattataaa ttgctattgt ctgcccatcc tgtttttgga
    28801 agggtacaaa tcacccaagc agactttcaa aatcctcagg tacctaatac ctttaccatg
    28861 attatgcgta aatacctcca gggtgcagtc attgagcagt tagaacagat tgataatgac
    28921 cgcattatcg aaatcaaggt atctaataaa aatgaaatcg gagatgctat tcaggcaacc
    28981 ctaatcattg aaatcatggg gaagcacagc aatatcatct tggtggaccg tgcagaaaat
    29041 aaaatcatcg aatccattaa acatgttggc ttttcacaaa actcttaccg caccatttta
    29101 cctggctcta cctacattga gccccctaaa acagctgctg ttaatccttt tacaattaca
    29161 gatgttcctc tatttgaaat cctccaaaca caagaactaa cagttaaaag cttgcaacag
    29221 cattttcaag gtttggggcg agacaccgca aaagagttgg ccgagcttct gaccacagac
    29281 aaattaaaac ggttccgtga gttttttgct agacctactc aggcaaatct gaccacagct
    29341 tcttttgcgc ctgttctttt ctcagatagc catgcgacgt ttgagacttt atcagagatg
    29401 cttgatcact tttatcaaga taaggctgag cgtgaccgta tcaatcagca agccagtgat
    29461 ttgattcacc gtgtgcaaac tgaactggac aaaaatcgta acaagctaag taagcaagaa
    29521 gctgagctgc tagccactga aaatgctgaa ttattccgtc aaaaaggaga attattgacc
    29581 acctacctca gtctggtccc aaacaaccaa gactctgtga ttttagacaa ttattataca
    29641 ggggaaaaaa ttgagattgc cttagacaag gctctgacac caaatcaaaa tgctcaacgt
    29701 tattttaaaa aataccaaaa gctaaaagaa gctgtcaaac acttatctgg attgattgcc
    29761 gataccaagc aaagtattac ttactttgag agcgtggact acaatttatc tcaagcaagt
    29821 atcgacgaca tcgaagatat tcgcgaagaa ttatatcagg ctggcttttt gaaaagtcgc
    29881 caaagagaca aacgccataa acgtaaaaag cctgagcagt acctggcttc agatggaaaa
    29941 accattctca tggtgggacg caataacttg caaaatgaag aactcacctt taaaatggct
    30001 aaaaaaggag aactctggtt ccatgctaag gatatccctg gaagtcatgt catcatcaaa
    30061 gacaatcttg acccaagtga cgaggttaaa actgatgctg ccgaactagc tgcttattat
    30121 tcgaaagcta ggttatcaaa tctcgttcag gtcgatatga ttgaagctaa aaaattacac
    30181 aaacctagtg gcgccaagcc aggatttgtg acttatactg gtcaaaaaac tttacgggtt
    30241 actcctgacc aagccaaaat tctctctatg aaattatcct gataagcaac taaaaaacag
    30301 ctctcctagg aaagttattt cccctaggag aactgttttt ttattctgat tgttggtgct
    30361 tgatatggtc aagaaagtct tgcatattca catcatcagg cacttgtctg aggtaagcgg
    30421 tagccatttg gatagccttg tgaaactggc caaactccct taataaatag gcataatcct
    30481 gtaaaaactc cggattttct gccaaatcag ccgaaatctc attataaaga gccaaggcaa
    30541 cttcttcttg ttccaaggcg tggtaagcct ttgcaatggt ccatttggtt aagacattat
    30601 caatcgtctc acgattaaga gcaataacct cctcaaaacg ctcggcatca aaataaaggg
    30661 tcactaaacg catgagaatc tcttcgtcat caacagctac ttcctttgct tgaagcaggt
    30721 aattttcagc attctgccta tcgtgtaatt cataagaaag ctgcgatgct agtaataata
    30781 attgactgtc aaatgcattt ttacgtaggc cctgttgaac caagcgcaaa gcttctgacg
    30841 tcttatgctc ttcatgaaga ctcaaagcat aaccatattc ataacctgga taatctggat
    30901 tgatggtttc caactgttta aagtaaagat tagctttttg ataattttct tggtcataca
    30961 agagggtcgc caattcaaaa acagtttcat cttcgtattc aatggccacg gccttttcca
    31021 agaattcgat ggctgcctca aatttcccta agctagcata ggctcgtcca atgcgttgat
    31081 aagtggaaat acctgtcaat tcaaggattt gacgattgtc taactgtgca tagtaatcaa
    31141 tagcttcttt aaaatactgc aaggacatgt caatttctgc caaaccaaaa atgaccaatg
    31201 gctctgggct gatgctcact gcttgaagca atttttcacg cgccacctct gtcagtcctt
    31261 ccatgtcata gaggtcagcc attactaaga gagctgacaa ataattgggg ctatcttttg
    31321 aaaccttatc caaatacaag aaagcttctt caatggcgtc gtcttctgct gcaatctgag
    31381 ctaaatttat attgagttct gggtaatcat cagctaactg caaataaata cgcttggcat
    31441 gtggcaaaaa acctatactt tctaagtatt ctcctaaggc gattaaacta tctgcatcat
    31501 cttcttttaa agctttttgg aaatattttt cagcgtgcgc taggtcttgc tgatccaagg
    31561 aagcaatcat tttttcacta tttaacatgg tccttaacct cctcaatcac caatacttct
    31621 tcgtcataca aaccgctaac ttttttgtac cagtcaaata attctttaat cacaactttg
    31681 acagaagcgt agattgggat gactaagaag acaccccaaa cgccaaacat tgatcctgca
    31741 gtcaacaata agaacatgat cgtaatcgga tgaatgctca gcttatttcc aagaacaagc
    31801 ggtgccacaa aacggccttc gatggtttgc tcaatcataa agataacaag caccttaacc
    31861 aacataaatg ggccttgtac catagccata atcacaacag gtatcatggc aaggaaactt
    31921 cctaagtaag gtatcatgtt aagaaagcca gcaataatcc caaaagtgat ggcatatttc
    31981 agtcccacaa gactaaacat gatagaaaac ataaagccga caacaattgc aaccgtaacc
    32041 tgcccttgga catagcctga taattgcttg ttaatatctc ccaagactcg aaccataggc
    32101 acccgtaatt tgagaggtaa gacattcaca aggccatttt tcatgtggct actgtctcgt
    32161 aaaaaataaa agagaataaa gggcgaaata ataatagcca cggtaatccg agcaatggca
    32221 ccagcaaaat taccagccca gtcaatagca ttttttgaaa aactttgcgc gtaatccaaa
    32281 gccttttgac ttgtatgggt aagcatgtct tggagttggg gcttgtagct gactaaccat
    32341 tcattttcaa gaagtttatt ggcttcttca ttgaccttgc ccacatattt gggcagatcc
    32401 tcaataaaac tggtaagttg ggtctgtacc atgggaacaa agcctgaaat cgcccagaca
    32461 aaaagtaagg taatcaaacc aaaaacaata aaaatagagg tggtacgatt cgggcccaag
    32521 tgattaataa ggtcaactaa gggtttggtc agataataca gaatggtcga aataaccaag
    32581 ggcaacatga tgaccgcaaa aaaagaaatc actggcataa ataaaaaaga gattttagta
    32641 aaaacaaaaa tcgttaaaaa ggctaaaagt gttattacta aagccatggt agcttgatta
    32701 tttaaaaacc atttgtaaaa taagctatct gttctagact tgtcaggtat taagggcatt
    32761 aagatagggt tcctttcttt gggaaaatga taagttttac tggtaacctg ggtaaatcaa
    32821 taaaaggtca cagatttatc catgagttgg ttgttttggt cataggtaaa tttggcagag
    32881 aaaaaaggac ggtcttctaa aatccattta aaaatgtcat aatcaccttc ccaagttggc
    32941 ttttccaaca cttgatcgta aggtacccat tccaaggttc cttctcgtga ctcttcatcg
    33001 gaaatgaggt ctccttcaaa tcctgttact ttaaaaacat aggtatacca gtcatgacca
    33061 ggggtaaatt ctggaaaagt aatgattcct ttaaaggcca tctctgtaac agtcaaatgg
    33121 gtttcctcta aaatctcacg acgggcacac tcatctgggg tctcaccagc ctcgagctta
    33181 cccccaactg aaatccactt gcctttgtgg acatcatttt cttttttatt gcggtgtaat
    33241 aatagcaaag aatcgccatt atcaatgtaa caaatggttg ctaattgagt catctatctc
    33301 tttcctttcc atctttgttt ctattatacc aatctctaga aaatatgcta tcattttatg
    33361 agtcaaagtg tgaatactta gtcacgctca aaaccttcta aagatgcctt aaaaaagtgt
    33421 agataagagc ctacaatgaa aaacatcaat ttaaactatc aaaagaacct tgtcatatca
    33481 acgataattg atatgacaag gttctttaat gttttattta atcacttctt gagttttagc
    33541 atacttggct tctacagcat ctttttctgc tttccaccat gtctcatttt ctgtatacca
    33601 cttaatagtt tcttccaaac cttctgaaaa gtttgtaaat tgtggttccc agccgagttc
    33661 ttcacgcaat tttgtagaat caatagcgta acgaagatcg tgaccagcac ggtcagttac
    33721 gtgatcataa gcgtcttttg gttgacccat tttctcaagg ataagctcaa gaacttcctt
    33781 gttgtttttc tcgccgtcgg caccaataag gtatgtttca ccgatacgac ccttagtcaa
    33841 aatagcccat actcctgtag aatgatcatt agtatgaatc cagtcacgga catttttccc
    33901 ttcaccgtat agttttggct tgatgcctga taaaatattg gtgatttggc gaggaataaa
    33961 tttctcaatg tgctggtaag gtccgtagtt attggaacaa tttgaaatgg tcgctttcac
    34021 accgaaggaa cgtacccatg ccttaacgat aaggtcagaa gctgccttag ttgatgagta
    34081 aggtgatgat ggattgtatt ttgtttcagc agtgaatttt tcacctggtc cttcaccctg
    34141 tcctggaagg tcttcacgaa gtggaagatc tccataaact tcatcagttg acacgtggtg
    34201 gaaacggata tcgtatttac gagctgcttc aagcaaagtg taagttccga taaagtttgt
    34261 atggataaat ggacttggat cttccaatga gttatcgttg tgactctcag ccgcatagtg
    34321 aacaatagca tccgttttgg cagccaattt gtctaccaat tcagcgtcag cgatatcacc
    34381 aacaactaac tcaacacgat caccaagaat agcttcaatg ttagcacggt tacctgcata
    34441 tgtcaattta tcaaggacag ttacatgaac atctgggtgg ttattgtaga catagtgcac
    34501 aaagttagat ccgatgaaac cagctccacc agttacgata atatttttat acataagata
    34561 taaagggacc tttcgtttcc gaaaaaatct attaaaagta ataactctaa caaagacgtt
    34621 ttaggcctaa gaaaacatcg ctttctaaga tttgagtccc atgttcagct caaagagaga
    34681 aactgaactt tcctttcatc atttttagtt gttacttgtt acctgaagta gagaagaata
    34741 actcccctca tatccacctc aaatgattaa tcccaatcat ctgagtatgt tgtttcccta
    34801 taggtctttt ggtttcagtg gtttgacatc actaagaaga ggatggtttt tatctgcttc
    34861 agaaacttct gcagctgcta gattttccca agtaatccca agacttgggt cagcatagtt
    34921 tacaaaagca tacttaggtt tcaagtcaag agcccagtag tcattgacaa gataactgta
    34981 agagacagtc tctgaaagaa cttgaaagcc attagcaacc cctctaggaa caaacattcc
    35041 ttttgaagca tcaatcactg tctggtagac gtttccaaaa gtctctccct cacgaagatc
    35101 aacccaagct cctaaaacct tgccatcatc agcaactgag atgtatttat cccaaggttc
    35161 agcatgaagt ccacgcagca catgctgacg tgaaaaagaa acgttgtttt gtagttttcc
    35221 ttcctcaaaa aaacgttctg gaaagccaat tggcaacatt ttttcttttt ggaaattttc
    35281 tttaaaccag ccacgattat ccccacgaac aggaatatca aactctagta agcctgggat
    35341 ttctttgatt tctcggcaag ccaatggttt gtcaaaaaaa gtttctgtca ttaagcttct
    35401 ccaatcaaac gaagcaagta ttgcccgtat tcgtttttct ttaaagactg cgccaattca
    35461 tggacatctt ctttactgat gtaacccatg cgataggcaa tttcttccag atttgccact
    35521 tgagcgtttt gcaaacgttg aactgtttca atatattgag ccgcttcaag tagactttca
    35581 tgcgttccag tgtctagcca tgcaaaacca cgccccatca attcaacgga gaggtcacca
    35641 cgttccaagt aagccttgtt gacgtctgta atttccaact caccacgcgc gcttggttta
    35701 atgtttttag caatttctac cacgtcattg tcatagaaat aaagtccagt cactgcaaag
    35761 tgggacttag gcacttctgg tttttcttcg atagagatag cattcatgtt ctcatcaaat
    35821 tccaccactc caaagcgctc agggtctttc acttgataac caaaaacggt ggctcctttt
    35881 tctttggcag ctgccttttg aagcatttta gtgaggccat taccgtggta aatattatct
    35941 cctaaaataa gagcaacacg gtcatcaccg ataaactcct ctccaataat gaaagcttgt
    36001 gctaaaccat ctgggcttgg ttgttcctta taggataagc taatgccaaa ttctgaccca
    36061 tctcctagca attcttcgaa acgaggaaga tcttgggggg ttgaaatgat taaaatatct
    36121 ttaatccctg ccaacatcaa ggttgacaat gggtaataaa tcattggttt gtcataaatg
    36181 ggcatcaact gtttagatgc ggcacgggtc agtggataca agcgtgtccc tgaacctcct
    36241 gcaagaataa tacctttcat acgtagtgct cctattcttc tatataccct atcattctat
    36301 cattttttga aagcagtgtc acgctttacc agtagaccgc aaaaggtaag gctcagggga
    36361 atagtcgcta ggcgttaaaa gtccttcgtg tcctagcaat aattgagcta attcatagcc
    36421 aatcaaaggg ccaactgtta atcccgatga ccctaaacca ctagctgtat aaaggttctt
    36481 caatcctgga acctgaccat aaaaaggaga ataatcactg gtataagctc ttatccctac
    36541 acgacatgat ttttgagtag cttcttttaa taacggcaaa taagtgagag cttgcatttc
    36601 aagtttttct aagacctgcc aatcaggctc caaatcataa cctttatcat tttcatggct
    36661 cgcaccaaca gaaatcttac cttgattgaa aggaatgagg tctatttcac cttctggcat
    36721 aacaacggga taattgtcgc tgatgatgtg atgaacgtca taatccaaga gttgtccctt
    36781 ttgtggtcgc acatcaacct gatagcctaa aggcatcaat aagtcaggta gccatgctcc
    36841 tgctgccaga atgacctgat caaaataatg accagcaatc tcataaccac ttccttgctg
    36901 tttcagagtg actttttggc gaataactgg ataaccacta gtcttgagta acgtctcaca
    36961 taaagcggct ccctccactc tagcagctcc tgaagcgtac agacagttat caaagccaat
    37021 caatccttta aaatcatccc ccagttcttt acgattttta atggctaact caccaataat
    37081 cggtgattct acctttcttg ctaacgctaa ttcataaaga tctcttagtt tttcttcctg
    37141 cttttttaaa acatagatgc cattttgctg ataaaaatct gttgcaaaac catcttcttt
    37201 gaggtcattg attaattgct gataaaagtc cgctcctaaa cgagccatgc ggtaccaaac
    37261 tttattgcga cgctttgaaa accaaggact aataatacca gcagcagcct tagtggcttg
    37321 tccttgacca tggtcaaaaa tggtaacttc tttttgacca ctttgttgta aataataagc
    37381 ggcggttgat cctacaatcc ccgccccaat aatggctatt ttcattcctg gtatcctttt
    37441 atcttacttt aagaccttaa cagcctataa atggctaaat ggattggtcg aggctttgct
    37501 tgaaataatg ctgacatccc aaccgttctc ttctttccac ccttggagtt tctcctttaa
    37561 tttctccgta aaaagcacct caatatgatg ccccgggtca accgcaaata gtccttctgt
    37621 cagcatctcc tgtgctgtat ggtaatagat atcccctgta atataaacgt ctgcgccttt
    37681 ttgcacagca tcctgataaa attcaccacc acttccgcca cagatagcaa tctttgaaat
    37741 caaagggttt tccttatcgt aacggataag tcgcacggta tctaaatcaa acaccctttt
    37801 gaccttactt gctaactctt ctaacgcttg ttctttaact gttccaatac gaccaatgcc
    37861 aaagccttct ttggtttcag acaagtaagt tgcttccttg atttctagca ggtcacaaaa
    37921 ccaatcattt agcccgcctg gtacaatgtc aatattggta tggctcacat agacagaaat
    37981 gtcatgcttg accaaatcta gaaggatatc acgctgaggg gatgaaacca gatctttaag
    38041 cggtttaaag atgggagcat gcttagttat aatgagatca acttcatttt tgatggcttc
    38101 tgctactgtt gactctcgga tatctaaagt aatcataacc ttacgaatgt ctttatccaa
    38161 tgaacccatt tgaagacctt taacgtctct ttccatagat aaatcaagtg ggcaaaaggc
    38221 ttcataggca tcaattaggg ttttagcttt catgaacaat cacctctttt atttgttgta
    38281 tttttgtcaa gagaagctga cgctcttgag ttttttcttc tgggatgcag gacaaggcat
    38341 aagctaactt atccatttct cgttgccact tctctttaaa aacgactgat ttttcctgag
    38401 aaaggtatgg accaaaacgc aattctgtcg cggataaggc cttttcacca tgctcagcaa
    38461 cgatgatttc ataatatttg tcattttcag ccatgatggt ttctgcaaca attttaaaag
    38521 cgttaaccga taaccaagcc cgtaaatcat cctcacgatt gttgggctgt aaaaccagac
    38581 gttcaatgcc ctgcaatttt tccttacctg cctctaaaat atcagtaatc aaacggccac
    38641 ccatgccaca aatggtaatg gctgtcacat catcagcttc ttcaaaggct gcaaggccat
    38701 tggctaagcg cacctgaata tgctcggcaa ggccagactg tgtgacattt ttaagagcag
    38761 attcgtaggg acccctaacc acttcgccag caatggctgc tgaaatctga ttagtttcta
    38821 ccaaaaatat gggaagatag gcatgatcac tgccaacatc taataatttg acaccttttg
    38881 gaacataggc cgcaacttgg gctaaacggt ttgataattg actatccatc ttgatttctt
    38941 tctaaaacgt aatggttcta ttatagcaaa attacctcca taaaaaaaga aaaccaaagg
    39001 ctaggctttc gattttccat aagtattttg atagtactta cagtaagact gaacgggaca
    39061 aatctcacat tttggttttt tggctaaaca atggtagcgt ccaaagaaaa tcaatcgatg
    39121 gtgagtaata atccaatctt tctttggaat tttagccatc aaatctgctt caatctgctt
    39181 gacatcggca tctggtgatg aaatattgag cctctttgag actctagcca catgagtatc
    39241 aaccgcaata gctggaacac cataaacctc tgccaatacc acattggctg tttttcggcc
    39301 aacacccggt aaactttcaa gctctttgtg ggtttttggc acttgaccct taaaatcatc
    39361 acgaatagcc tgagcagttt taatgatatt tttggcctta tttttataga gtccaatcgt
    39421 tctcagagca ttttcaacat cagaaagttc agcaaaagct aagtcttcta tttctggata
    39481 agactgccat agtccaggag ttaccttatt gacggcctta tctgtcgttt gagctgataa
    39541 aatcaccgca attaacaatt gaaaaggtgt ttcccagtct aactctccct tagcctcagg
    39601 aaacatttga ccaatgatgg tcaggacttt tgctaatctt gcttttccaa ttctcatgaa
    39661 tcactccata aattcatcgc agatagaaaa tcctctgata tcgtcacttg agaaagatct
    39721 tcgccttctc taacacgtct acgttcttct acttgtcgaa gattaacaat accttctttt
    39781 cgccaattac gtaagatagc ctggatatat ttccaatttg ttttgccgtt gaagacagct
    39841 tcttttaaag cttctcgtat caaatcagga tctgttttat catcacgaag cgttttttca
    39901 agatcttcta actcaaaagg actcaagaat cgtcctaatt cacgttcaaa ttcatcaact
    39961 aatcgtttga aatggtttgg tgtttcttgt ttgtcaattt cagttgccgt ttgactgaca
    40021 aacaattgat ctaacttggc taacacagga ctcgcatcaa aaataatttc aatttctcca
    40081 gtaagttcaa ttgtccgcat atctaaaagc ccttgactag tcaaagatga aatgatttta
    40141 ttaatatcag caactgattt tccaagcgca tgagcaattt gactgggcgc taagtcgtct
    40201 cgctttgtcg tattttgaag atagaaaaac tgccagacca aaaaatcatc tgagctctta
    40261 aaaagatctt tgtaatgaaa aagcaaggca cttgggataa ccaaattacc tgacttataa
    40321 tgttctaaaa aactcataat ccctcaatca aaaggctaaa atcgaatcta tagcctttac
    40381 tactttaaat cccctaatca gatgctgatt aatgtgctta cccaggaaac tgcattaaga
    40441 ctttatagtc atagttccta atagcatgac gaccatttaa accttctaat tcaataagga
    40501 aggcacaacc agctacaata ccaccaagtt tttcaatcat ttcaatagtt gcttttaccg
    40561 taccgccagt cgctagtaaa tcatcgacaa tcaaaacacg ttgtccaggc ttaatagcat
    40621 ctgcatgcat agttaaggta tcaagaccat attctttttc gtaatcggca gagacaacat
    40681 ctcttggcag ttttcctggt ttacgaacgg gagcaaaacc aattcctaac tcaactgcaa
    40741 caggacaacc aatgataaaa ccacgcgctt caggtccaac aaccatatca atatctttat
    40801 cacaagcgta ctgtgctatt tcacgaatag catagctata tgctttaccg tcagccatta
    40861 aaggtgagat atctcgaaac gtaataccag ctttagggta atctttgatc gatgcaatgt
    40921 aatttgttaa atccatagtt aattctttct agtggcaaat tgccaaatat aaaatactct
    40981 tcattatatc acgaaacata tttttcgtaa aataagactt ctgacattat gtttatctga
    41041 tacttcattc gtaactacct caataactac tgtcaactgc tttacttatt gatcgtttga
    41101 tttcaccaaa taatcataca tctctttcgg gctagccaaa gccatgattt cttgaaattt
    41161 caccaattct tttaagtctt ggtaaatgtg gctctctgaa atctctcgtt tttgcgcttg
    41221 ggggttaacc gtcatcagcc catcgtcaat cgtcacaaaa gacaactctt caaaaatttg
    41281 aatcaactta atcagtaaaa gtttttctat gtttaaatag tgactcaact ctgtcaattt
    41341 atgccgtaaa tcaaattcag gaaactgata gatggttttg tagagcttgg caaactgctc
    41401 tctgctgcca aatcctgtta aataataagg atgtttcatc tgatttttaa aatagatggc
    41461 gtcaaaatcc ttgtgaacaa actggttgcg ccaggttttg aaatcttcag ggatgtcatt
    41521 aatcagaatg actctggcat ttgggtcttc ttcaatagtc ggaatacctt caggaacttt
    41581 ggctgttttt gtccttaagt caagaagttg cactccgtca acacgagcat ctactaacat
    41641 gaattggaga ctcgtgttcc cattccaatg gttgacagat aaggtaactg ctaattctaa
    41701 accagtagct tgtcggaact cttgcagttg acttccttga ccaaaagcca gtacgtcaaa
    41761 ggaagctttg ccctgactga ctttaaattt aagatggctc tggtcttgcc ctatggtacg
    41821 cgcttgacta acccttatgt ccttgacata aaagaccggc ttttgatgat ccatcccata
    41881 aggggctaat ttatctaaac tctttaaaat atcaaggcta aggtcgtcca aagacagtct
    41941 ttcatcaata gttaacgtat ttttggcagt ctgatctaag ccacgttcta tcacaaactg
    42001 acaaagaaag tctgaaagag cttccaagtt gtcaacgggc agggtcattc ctgctgcacc
    42061 agcatgtccc ccaaaggctg taaataactc acgcttgcca ttcaaggctt caaaaatatt
    42121 aatagcttct aaacttctgg ccgagccttt tgcaaagcca ttatcaatgg tcaaaacgac
    42181 gaccgtttgt ccaatagttt ccatgatacg accagcgaca atcccaagaa caccaggatg
    42241 ccagccagct tgtgccaaga cttgaacagg tttttgagga tcaaccatag ccatcgcttg
    42301 atcaaaaatg tcttggacta aggccttacg ctcttcattt tttttcttaa tcatcaaggc
    42361 aatcgcttga gcttcttggt catcaaagcc cgtcagtagc tcaatggctg gattagggtc
    42421 atctaagcgc cctaaagcat ttaattgcgg agcaatctga aagccaatag cgtcttcatt
    42481 aaaatgttcc aaatcaatag gagacaaaga catcaactcc tgcaagccca ctctttcggt
    42541 gtgtttgagc atggccagac catttttgac taaaacacgg ttttcacctg tcaagcttac
    42601 catatcggca atggttccaa tagctaccaa gtctagacag tctgttggta aactttctag
    42661 caaagctgtt gccaatttaa aggcaacgcc acagccagct aagtgtttaa agggataatc
    42721 agcatcagga tgctcaggat gaatgatggc aaaggcttct ggcaattctt caggcaggct
    42781 atgatggtca gttacaatga catcaacttc ctgttcttga gcatatctaa tcgcttcatg
    42841 tccggccacg ccattatcaa ccgtgataat tagggacaca gcttcctgct caataaaata
    42901 tttatagacg ctctggttgg ggccatagcc atctgtaaag cggttgggaa gataaaccaa
    42961 aggctctgct cccatcatgt ctagggtttc tttgacaata gaagccgacg tcatgccatc
    43021 agcatcatag tcgccgtaaa tgagaattcg ttcgccctct tcaatagctt gacgaattct
    43081 tggcacagct tttgccatgt catgtagcaa gtaaggatca tgcagttgag acaagtccgc
    43141 tgttaaaaac tcatctaagg cttcttcagt ccttatccct cgctcataaa tcaactgagc
    43201 ggcggtctgg gttagacctt ttgtctttgc tagcttaaag aagccatcat ctggcttctt
    43261 gtcttttatt ttccagctat atttggattt aatcatttat aattaaatac ctttcttgca
    43321 agataatcag ataatttagg gaaaagggtg taaaattgat gggtcaccgc taaactaaag
    43381 ggcaaattca attctcgttt atttttcccg ataatagaaa ccaaacgctt agccacttga
    43441 tttggttgga gagtaaatgt accaacgctt tccaaataat gtccagacgg gtcagcttgg
    43501 tcaaaaaact tggtggcaat gggacctgga ttcacggtgg tcacgtaaac ccctttatcc
    43561 gctaattcta agcgaagggc attggaaaat ccgataaggg caaacttggt ggctgaataa
    43621 atgctcgatt tggctgacgc aatcaagcct gccatggaca caatattaat aaggtgacct
    43681 tgcccctgct ctgccatttt ctgaccaatc aagcaagcaa agtgaatgct cgctagggtg
    43741 ttaacctgaa acatatcagc tatttcttgg gcagaaaact cttcaaagcc tttgaaagct
    43801 ccgtagccag cattattaat caagacatca atacggccat agcgctggta aatctgggcg
    43861 accattttct caatggctac tggattggta atatccaact caaggcattc tttgttgtca
    43921 atatgctgat aacagtgttc taggcgttct ttgttacgtc ctaataaaat caagctgtct
    43981 tccttgggta actgcttaac aattgcctga gccagtcctc cagaagctcc cgtgataaca
    44041 atgattcttt gtgccattaa ataatcactt cctctaaatc ttgtaccatt ttaacatttt
    44101 caaatatagt ggcggcatct ttttccatct ggcgacaatc acgccctaaa aagcgagctg
    44161 atacatgatt gagcaagagg cgttttgcgc ctgcttcatg agcgatttgt gctgcctgca
    44221 tgttggtaga atgcccgtga tttctcgcaa tccgctcgtc acccttacca taggtggatt
    44281 catgaaccaa aacatctgca tctttagcga gtttaacact ggcagacgtt ttgcgcgtat
    44341 cgccgataat ggtgatgatt ttgccttttt taggggcaga aatataatct ttggcacaaa
    44401 tcaggcggcc gtcttccaac tcaacatctt gaccattttt aattttgcca aagagtggtc
    44461 cgaagggaac acccgctgct tttaaggctt ctgcgtctag ggttccttct aagtcttttt
    44521 gaactactcg ataacccatg caaaaaatgg tatgcgccag acgctctgca tagaccacaa
    44581 acttatctgt ttccattatt ttacctaatg atttgtcatc aaattcatga aaatgaatct
    44641 gataaggtac acgcgctcca gaaactttta gactagttaa cacgtaagtt ttaatgccaa
    44701 ttggtccata aatatcaaga tctgtctgtt cttcactagc ttgaaaagac cgacttgata
    44761 aaaatcctgg taatccaaaa atgtggtccc catgcaaatg agtaatgaaa atctttctta
    44821 tttttcgtgg cttaatcgtc gtttctaaaa tttgtctttg cgttccttca ccgcaatcaa
    44881 acatccagac ttcattgatt tcgtctagta atttcaaggc aagacttgac acattgcgct
    44941 gcttggctgg ttgaccagct ccagttccta aaaattgtaa ttccattcaa tctattcttt
    45001 ctattgggtg atgtaaatca taaattctcg ttgggcaaaa tcataatact tttgaccaga
    45061 aaatgtttgg ctaagagccc ataactcctc tacattaaac cccttaagca tggtgatacc
    45121 gtttgccaga cggtaaatct tcgacaagag tgtgtcatca ggcgtaatgt cttcacattc
    45181 tccttgctca aactgcttag cctgcatttt aagctggcct ttgtcttcat aaaccatata
    45241 ttgtgggaaa atttgtgtta attcaaagaa gagttcgggt ttcttaggct ctgctttttc
    45301 agaaaatacc aatgcaactt cttggtcatt ttggtaagca aaaccataag cttttccaga
    45361 caaattgagg cgtacaaagg gcttttcttc ctcaaaagat ggttggtcag taaaaagccc
    45421 caaagcctta gaaagattaa aataataatc agtcgcagct tgcggtgact gtttctggta
    45481 gatttcagca aagtaggcat taataacact tggtggtggt gtgataaaag ctagtttttg
    45541 ctggtctgtc aaactggcta atagatggtt taggtagttg gtatccagac tagtaaatcc
    45601 accataggtt tttgctaaat caatataatt attcataaaa atcgtcaagt ctccattgct
    45661 gttttgggga aatgtagccc gaaatatcct ctatttcttg gtcaaacgtg tagtggtcta
    45721 aaagagcaac tcggttcaaa tcatacagct tgtacgcctt gtcttgatgc actttgattc
    45781 taaaaggaac aaactggtct cgaatttggt caatgattaa acgtctcaag agaattttgc
    45841 tatcctttga acgggctgaa atcctaatat ttggaaaagc agtagctgtg aattgttctg
    45901 ctatatccac cttgttataa atagctaaac gtggaatatt aagcatgtct agctctttta
    45961 gaaggtttaa aaccactttt tcttgctcac tatgattagg gtcgctagcg tcaatcacat
    46021 gtaacagcaa atccacatat ttgctttctt ctagggttga tttaaaagca gccactaatt
    46081 ccgttggcaa gtcttgaata aagcctacgg tgtctgttaa ggttgcttga aattgatttt
    46141 ctaaatagag ttgctttgta gttgcatcta aggtagcaaa taattcattg gcttcatagt
    46201 ggctgtcatc tgtcaacaag ttcataatgg ttgacttgcc agcattggtg tagccaatca
    46261 agccaatttt aaaggtatct gaacccacac gacgatctct aattgtttga cgatttttct
    46321 ctacctgagt taattggcgt tcaatatcag caatctgatg acgaatcgaa cggcgattta
    46381 actctagttg gctttcacct ggtccacggc tcccaatacc acctgcttga cgacttaaca
    46441 tgatgccctg tccaaccaaa cgaggtaaca tatatttcaa ttgggcaagg tgtacttgta
    46501 atttgccctc atggcttctg gcacgcatgg caaaaatatc taagattaac tgcatacggt
    46561 caatgacttt tacctctaaa acagcttcta gattagcatt ttgcctagca gtcaaccgat
    46621 tgttcacaat aactgcatca atctcatcag cttccacaat cgccttaatc tcatccagtt
    46681 tccctgagcc gataaaggtt ttgctgtcgt aacgttctcg tttttggctg aaacttgcca
    46741 taactttgac gccagctgtt ttggcaagat tagctaattc tgtcatggac atatcaaaat
    46801 gttctgttgt ctgaagctca actcctaaaa gaatcactct ttcttgctga cgctttgtct
    46861 caatcatcac ctttaccaat cctccaaatt ccgtaaattc tattataaca tatcttcaac
    46921 agattctgct aattttgcgt catgacttct ctttctgacc aagaaaatcc ctgaccctat
    46981 catgtactac ctgtgggtaa tcaggagccg ttatggcagt gaagctaaca gccattcgat
    47041 tgcggaacca agttagctgt cgcttggcaa aacgtctcgt gttttgtttt aactgatcac
    47101 tagcttctgc caaagtcatt tcacctacaa aataggggaa taattcctta taacctatgc
    47161 cacgactagc ctgaacagtc gggtaatgct catataacca ttttgcttct tccaataagc
    47221 cgttttcaag catacgatcc acgcgctgat tgatacggtc atagatgact tggcggtcat
    47281 cattcaagcc gataataagc ggctcataag ccgtctcggc attctctaat tcatcagcaa
    47341 actgagccaa ttcaagggct cggatcgccc gcctgcgatt cacctgctca atggtaatgt
    47401 tattgacttg caagcgttca tacaagtcgt gatcgtccaa ttgctccaac tcattccgat
    47461 aggcttttac cgcctcttga tcaacttgac ctcctagatg ataaccttcg agtaaacttt
    47521 gtaagtaaag accagttcca cctacaataa ttggtaattt cccacgacta acaatgtctg
    47581 aaatagcttt ttgagcatct tgaacaaaat cgtaggccga ataagactcc gtcacctcac
    47641 gaatatcagt taagtgatga accgctgctt cttgctcttc ttgagtggcc ttggctgttc
    47701 caatatccaa ctgtcgataa acttgctggc tatctcctga aataatttct ccattaaaag
    47761 ccttggctaa actaatccca agtgctgttt ttccaaccgc tgtcggacca acaatcacaa
    47821 ctatttttat ttttgtcatt ttcttgtctt tctattagaa aagcgtgtcc aaaaacgcct
    47881 tttacttgaa aattagctta tttttcgcta ccatatatta taacataaga ttaaggacca
    47941 ctgaggtcct tcactagaaa tggagaataa tcatggaata tcaatttgtt aaaggtcttg
    48001 ctactggcgt cctagcaact gctgctactg ttgctggtgc tgtctttgct gtaaaaaaaa
    48061 caatcattga ccctgaagaa gaaaaagctg ctttcattga agaaaaccgc aaaaaagctg
    48121 cgcgtcgtcg tgtagctcgc taacgtgaca atggatcaat ttaaaagaga ctagcacatt
    48181 aaagtgccgg cctctttttt agtaatctcg ataactagtt agtagtaact gtctcttgat
    48241 gagccaagat gttagctgct ttacttattt tgaaatagaa atctcaggta agccccataa
    48301 acatacgtga ctaaagctgt cgccaacaat acctctccta gcaaaagaac ctgccaacct
    48361 aaaccttgcc aacctaaaaa agataaggtc atttttaagg aagtggcact aatcacaaac
    48421 ggaaaggtaa aagctgaaaa acctgggtta aagggacgat tgagtaagcg aggaagctgt
    48481 acaaccacaa aagcatataa cagttgtgag ctgatgagaa gaaagataac cattcctact
    48541 tgtggtctag gaaaggttgc taaataagac gctgaaagta aggacagagg ggcacaaaac
    48601 gttgaaatat tgggcattac tgcttgacct aaaccaatcc cataagtctt tttggccata
    48661 aaaggtaaaa tcacagcagt taagagaaga caaacccaaa aaatcacctg tcctaataaa
    48721 aactgcctac tagcaggtgc tgttaatgcc gccattgcaa ttccaacaaa aagcacggac
    48781 caggaaggaa aaacgttatc ccatgaaaaa gaaaagacaa aacgatactg gtaataagca
    48841 atcaggacaa gatttcccaa aaagaatagc caccaagtga gaaagcctaa ccaacaccct
    48901 cctgtcactt tgagaaagag tgaagacaac aacatccctg tcataaaaaa agttggaaaa
    48961 acagaggcaa ttagaggttg tcgtaactgc attttggtat cgttaaggtt cctaaccatg
    49021 ccaacaagca agataccata aataaaaaga gctgccagaa ttcccaaata actaaaaatc
    49081 gaaacataag tagccaacaa attgccaaat gacaacgttc ctaatgccaa tcctgacatg
    49141 accaatggtg ggtttttaag gtgtttcata agtgtccttt tctgcctatt aacagctatt
    49201 tttagtgaca taatcttgtt tattttatca catttcgagc atttttgcca taaaggctgc
    49261 cagatgcgga taattctcgt aagattttgg tgttttttga gaccatagcg ccatggcgta
    49321 agcataagca tctgcaatgg tttgttgatc tcgataaaca tgcccactat ccccaataag
    49381 accatctaaa tgcgtcatag caatatccat ccgcttgtaa gaagcttgtt tgactttttc
    49441 aagcgcttga ttgtcttgag aaatagtgta gcgatgaggg ttgtacattg gcctaaaaac
    49501 aaggggaaaa tcacctgtta agaaatccat gatttcgttg aatcgacttt ctgccaaaag
    49561 attatcttgg ggaatgagct gagatttcag ggtttgtttc gctataaaga gcaagataat
    49621 acctgcctgt gtgacgattt gaccatcatc aagctgtaaa gcttaaacca ttcccaaagg
    49681 attgatggta aggcagtctt cagaatccag ttttaccttc tctatctcgt aatacagaaa
    49741 ctcacaattc ttttgaaaag gttctagaca gagttggtgt tgacgtcttc gctgttgatg
    49801 gctctgcatg acaaaatgag cttggtgtcc acgttcacta gtatcttgtt gcaaagtctt
    49861 tgcaatttgg tctcatcatc tgtatcacaa aaaacaaacc agtttcctga tttgttttga
    49921 gatattaggc acctacaaat tctggcaagg attctccaat agcttctaaa cgttctgccc
    49981 atccttgacg tgataaacca ttttcttgca catagcgatt acgttcatgt gcacgacatt
    50041 caggcgagca tcctcgaaca tactttgttt cgttttcttc tgaagcaaaa atttgtttgt
    50101 tacaaaacgg atttgcacaa ttgacataac gttcacaagg tgttccatca aaataatctt
    50161 tactaatgac agttggatta acatgattaa ttggcaccga gatacgatca tcaaaaacat
    50221 acatcgcacc atcccaaagt tcaccttgaa cttccggatc ttttccatat gttgcaatac
    50281 caccgtgtaa ttgtccaaca tctttaaagc cttctcgaac catccaaccc gagaatttct
    50341 cacagcgaac accacccgta cagtaaacaa caacacgttt ttccataaac ttatctttgt
    50401 tgtcacgtac ccattgtggt aactcacgga aattgcgaat atcaggacga attgctccac
    50461 ggaagtgacc taagtcatat tcataatcat tacgcgtatc taaaacaaca gtatcttcat
    50521 caagcaaggc ttctttaaat tgtttaggat ttaaatactc acctgttgtt tccaaaggat
    50581 taatatcact atcaaagtta ttgtcttcta acccaaggtg cacgatctct ttcttataac
    50641 gaacaaacat tttacggaaa gcttgttgat tttcctcgtc aatcttgaac caaagatcag
    50701 caaaacgctc atcgctgtgg acccaatcca tatacttctg agttgtttca taatctccag
    50761 aaacagttcc attaatcccc tcatccgcaa tcaaaatacg acctttaagc ccaatagatt
    50821 tacaaaattc tagatgtttc gcagcgtact cttgcgcatt ttcaattgaa acatatttat
    50881 aatagagtaa aactctgatt ttttctgaca ttttttctcc ttcattgtta ttcagttact
    50941 tcctattata tctaggaaaa acaagtctag gcaagtcatt tgtttgtctt ttttttcaca
    51001 aaatagatct caatttattt ttgatgagat gagatgcaac ccattactcc tttaagcaga
    51061 tcattagaag ctttatttag aaaatgctaa gataaaacaa ggaggccaaa atgacttatg
    51121 aactttgttt agaatatggg acttatccgt tgtcacgtgt ttatgcttat tggggagaag
    51181 atcaaaatcc cccaacattc attcaagaag atcgactgct ttgccataaa ctagaaacta
    51241 tgaatcacct gttccatgat ttatttgtaa ctattgaatc acaattccat tatgttggtt
    51301 ttaacatgcc tgaaaaaaga gcgcagattc ggatactata tcaagaagta gctactatat
    51361 taaaatccaa atataaggat tatccaatta agattgagac gtttcttctt taaaaatcta
    51421 atactaaaaa actaactgtg cttagacaga tgacacagct agttttttag gtaaaactct
    51481 tcttaaattt taaaacgttt cgaaaaatca ctaaatgctt taatagcact tgctaaaaat
    51541 ggtttcacca tctcatcaat aattaacctt gattacttac aatcttatga atctgagtca
    51601 aataaaattc aggctgtggc attacagaga tatttaaaac ctatactcat cgttttcaag
    51661 gtcagaaaaa taatgatttt gaaaaggttc gtcaactctt ctagataatt ttggacaaat
    51721 tttggaaaag aaacaaaaaa agcctatcaa atagggcttt tttatatgat ttctatccac
    51781 cttgagggaa tcgaaccccc atctcaagaa ccggaatctt acgtgatatc cattacacta
    51841 aaggtggtca caactttgtc aataccctta tagtatatca taaaatgaaa taatatgaaa
    51901 taacttttct aaccagaaga caataaaaag ttgaggaaaa cctcaacttt ttagatttat
    51961 tacaattcaa tatcaccgaa aagatcagcc attgagaatc cagtttgtgt ttctgggagt
    52021 tcgtagtcac gtcttgattc acgttttgga cgacgtgggc gtgattgacg tttttcttct
    52081 ttgttgtctc cttcagcttg cgctgggcgt tcttcaagag ctttgattga taatgatacg
    52141 cgctcatcag ctgcattcac ttcaagaact ttaactgtta cttcttgtcc tacagaaagt
    52201 acatcttttg gattttcaac acgtttgtgt gaaatttgtg aaatatgaac aagtccatca
    52261 atacctggta atacttcaac aaaagcaccg aagtcagtca agcgttttac tttaccttca
    52321 acaacatcac cttgagcaag tttttgttca acgccgtccc atggtccagg tgttgttgct
    52381 ttaagtgaaa gtgacacacg accagcttct tcgtcaattg aaagaacttt aacttcaact
    52441 tcttcaccaa ctgaaacaac tgatttaggt gacacattac gttcgtgaga caattcagtc
    52501 acgtgaacaa gtccgtcaac accaccaagg tcaatgaaag caccaaaact tgttaaacgc
    52561 gctacagtac ctgtaacgac tgcaccttct gaaatcttag agaacacttc agcacgagct
    52621 tctttagcgg cctcttcgat aacttcacga cgtgatagga tgaaacggtt ttctgctgca
    52681 tcaacttctt tgattttagc atcaaactct tgtccaacaa atttttcagt gttgcgaaca
    52741 aaacgagtgt caatcattga agcagggata aatccacgaa gtccttcaaa ttcaactgaa
    52801 agaccacctt taacagcacg ggtaccttta acagtaacaa cttcgccttc acgaccaaca
    52861 agtttgtccc aggctttacg agcttccaaa cgttttttag atactaggaa agtaactgta
    52921 tcagtatctt tacctactac ttgacgaaga acaagtactt caactgtgtc gccagcttta
    52981 acaaagtcgt taatatcagc atcgcggtcg ttagtcaatt cacgaagtgt caagacacct
    53041 tcaacacctg ttccttcgat aacaacgttt gcttgaccgt tatcaacagt taaaacttcc
    53101 gcagtgacaa catcaccagg gttcacttcg ctaacactgt ttagcaaatc ttcaaattca
    53161 ttcattctaa aaaatcctcc aacaaaagct agccaatgct agcttttgat aacaatatat
    53221 tttctcaagg taacccgcaa cgacaacaac tcttatcttt gacggtctca gggagcacct
    53281 gatacctctg actggggtag ctggattcga accaacgcat gagggagtca aagtcccttg
    53341 ccttaccgct tggctatacc ccaataaaat tttttacaga aaactaattt tctaattaga
    53401 ttagtttccg aaatggaaag agagggattc gaacccccga acccgaagga gcggatttac
    53461 agtccgccgc gtttagcctc ttcgctatct ttccgtaaca acaaaaacta ttctatcata
    53521 gtttttgtaa gctggcaagt gtttttgtct aattttaatg gttcaaattg tagttttcaa
    53581 tgatattttc aaccgcttgt tcgagcgttt tgaagaagca atctactcca tcatttttta
    53641 agacagcaaa tttctcatca agttctgcaa tttctccaac cacacgttta ccaatttgta
    53701 attgatagcc atcaatctta gtttcattaa ccataacttt gtgatcaatc agttggattt
    53761 caattttttt atctttttta ctcatcactt tacctcactt tgtctatttt acacaaaatc
    53821 aaaaaagctt gcaagagcaa gctctatttt aatctacttt tacaatccaa ccttctggtg
    53881 cttcaatatc cccaaattga ataccgacca actcatcgta taaacggcgt gtcacaggac
    53941 caacttctgt ttcactgtaa aagacatgta agttatcctt gtactggata ccaccaattg
    54001 gagagataac agctgctgtt ccacaagctc ctgcttccac aaatttatcc aattcattaa
    54061 ttggaacatc accctcaatt actgtcatac caagtctttc ttcagctagt tgtaagagtg
    54121 aatacttcgt aatagatggc aagatagatg gactaagtgg cgtaacaaat tcattatttg
    54181 cagtaatgcc aaaaaagttt gcagctccga cttcttcaat tttagtatgg gttgctggat
    54241 ctaagtaaat cacatcagaa aagcctgctg atttagcggc cttacctggt agcaaacttc
    54301 ctgcatagtt tcctcccacc ttagcagcac ctgttccgta aggagcggcg cggtcaaacg
    54361 cttcagaaac aataaaatta gtcggagcaa gtccaccttt gaaatagttt cctactggca
    54421 tggcaaaaat ggtgaaaata tattcttcgg ctggtttaac cccaataata tctccaactc
    54481 caattaataa cggtctcagg taaagcgttg cacctgttcc gtaaggtggt acaaagtctt
    54541 cattggcttt aaccacttgc ttagctgcat caataaattg ctctgttgat acttgtggca
    54601 tcaacaagcg gtctgctgtg gcttgtaaac gcactgcatt acggtctggt ctaaatagtt
    54661 gaatagagcc atctttggtg cgataagcct ttaaaccttc aaaagcttgt tgcccataat
    54721 gaagcgctgg agcgctttct gagatatgta aggtggcatc ttctgttaat tgacctttat
    54781 cccattgacc atttttgtaa taagaaatgt aacgaaatgg caacttatga tattcaaatc
    54841 ctaggttgtc ccaatcaatt gctattgtca tcatcgtacc tcttttctgc ttttttctat
    54901 tgtaactttt tttcaataat tttcaagttt attctactct tttgcattaa tattctaaat
    54961 ttaccataaa attaaaaaga gttttcactc tttttaacgt gttctagcta ccagtacttc
    55021 ttgatccgaa atagtgtctg aaataaagga gccattgctg gttctttccg ataacgaaag
    55081 cgtttctaaa gcaatctcgt aggtttgacc agtcttacta atgacttcaa gcatttgttg
    55141 attagtttct tcttcaggta tatcagtgaa caaatcaaac tgctcagctg aagtatctga
    55201 ttgaacgcct ccggccagaa aaactctatg aggtttggtt tttaactctc gtaggaccaa
    55261 tagtccacga ttggcacgac ttgtctgagg aatatcatcg acagccatcc gtttgagaga
    55321 acccctctga gttaagacaa agaaagagtt acttgtcaca gcaaaggctg aggcaaggct
    55381 gtcatcattt ttcaagttaa tgcctttaac accagcagat ttcaaccctt gaataggcac
    55441 ttcctgactg gagaatcgca aagcataacc atttttagtc actaatagga ggtcttccat
    55501 aataactggt gacaaggtaa ccacgcggtc tttgtcatcc tttagcttca catatttggt
    55561 tgatttagat ttataagttc gccaaggact tagttcttta cgatcaaagc gtttgataaa
    55621 accattttgt gtgacagcca catacaagcc ctggtcaaag gaagtcacaa tatcagcgta
    55681 gagaatctct tcttctgtcg cgaagtttga aatggtttgt gataaatgtt caccgatatc
    55741 cttccaacgt aaatcggtca attcatggat tggccggtaa atgacattgc ctaaagttgt
    55801 aaacaacaaa aggtgttctg ttgttttggc ctgtttaacg aagatgagtt cgtcatcatc
    55861 tctcttgcca acttcttcca aactagacgc attgaaggat cgtgggctgg ttcttttgag
    55921 gtatccgccc cgtgtcacac taacaaaagt ttcttcctct gcaatcaagc tggcagtgtc
    55981 aatctcaatg atttgacttt ctgcttgtaa ctctgataaa cgaggattgg cgaatttctt
    56041 tttcacttct cttaattcac gtttcatgac gttatacatg gttgcttcgt caccgataat
    56101 agcggaaagg gtcgtgatta agtctcttaa atcattttct tcattttgga gagtaacaat
    56161 atcggtatta gttaaacgat aaagctgcaa ggttacaatc gcttctgctt gttcctcaga
    56221 gaaatcatag ctgactttca gattttcttt agcatcagtc ttattgtcag acgatctaat
    56281 caaagcaata atctcatcta agatggacaa gacacgaatc aatccttcaa caatgtggag
    56341 gcgtttttca gctttggctt tatcgaattt agaccgctca ataataatat ctttgcggtg
    56401 actgatatag cttgatagta ttttttgaag ccctacttga cgtggtgtga agtgatcaat
    56461 ggcaaccata ttgaaattat aattaacttg aaggtctgtg tatttcaaca aataatttag
    56521 aatggtttgg ctatctgcat cttttttcaa ctcaatagct atgcgaagac ctgtgcgatc
    56581 agattcatca cgtacttcta cgatgcctgg gactttattg ttaacacgaa catcgtcaat
    56641 ctttttgacc aagactgctt tgttaacttc ataaggaatc tcagtgacaa taatttgttg
    56701 tttaccacct ttaagttcct caatttccgt cctagagcga acaacgacac gtcccttacc
    56761 tgtttcgtag gcttttttga tttcgtcagc tccttggata atgcctcctg tcgggaaatc
    56821 tggcccaggc aaaaattcca tcaatttctc taagctagcc ttgggatgat caatcatata
    56881 cacaacagca tcaatcactt ctgacaaatt gtgcggtgga atatctgtcg catagcctgc
    56941 ggaaatacca gaagacccat tgacaagtaa gttaggaaaa gctgctggta aaacggtggg
    57001 ttctttttct gtgtcatcaa agttccacgc aaaagagacc gtattttttt caatgtcttg
    57061 aagaagataa cctgcaattt cagacaagcg agcttctgta taacgcatag ccgcaggcgg
    57121 atcgccatcc attgaaccat tatttccgtg catttcaaca aggatttcac ggtttttcca
    57181 attttgactc atccgtacca tggcatcata aatagaggaa tccccatgcg ggtggaaatt
    57241 ccccatgata ttaccaactg atttggctga tttacggtaa cctttttcaa aagtattgcc
    57301 atccttattc atcgaataaa gaatccgacg ctgaacgggt ttcaatccat ctcgaatatc
    57361 aggaagtgcc cgttcctgaa taatatactt ggaataacgg ccgaagcgtt ctcccataat
    57421 atcctcaagg gacatgtttt gaatgtttga catattcaaa tagctttctt tttcattatt
    57481 tattaattac ctaaaaaaca atcgtcttta gcacttgtaa ttatctgtga gaaacttgta
    57541 tgactaaaac accgtatttt cttctaaggt aaacttgacg ttatcctcga tccactgacg
    57601 gcgtggggct gctttgtcac ccatcaacac agaaacacgt cgctctgctc ttgccaagtc
    57661 gtcaatagta acacgaataa gggttctggt ttcagggtcc atagtggttt cccataattg
    57721 gttagcattc atttcaccca gtcctttata gcgttgaaga atagctcctt taccaaattc
    57781 cttacgtaaa tcttctaatt caccatctgt ccaagcgtag gacactttct ctgttttacc
    57841 tttacctttt gacattttat aaagcggggg aagcgcaata taaacgtgac ctgcttccac
    57901 caacggtcgc atataacggt aaaagaaagt cagcaaaaga gtctgaatat gagccccatc
    57961 ggtatcagca tcggtcatga taataatctt atcatagttg atatcctcga ggttaaagtc
    58021 agctcccact ccagctccaa tggtataaac catagtgtta atttcttcat ttttcaagat
    58081 gtcagccatc ttagcttttt cggtatttaa aactttgcca cgtaatggta aaatagcctg
    58141 aaatttgcgg tctcgtcctt gtttggctga acctcccgca gaatctcctt cgaccagata
    58201 caattcattt ttcttggcat ttttggactg ggctggggtt aattttcccg acaacaagcc
    58261 tttgtctttt ttgtttttct taccattacg tgagtcatca cgcgcttttc gagcagcttc
    58321 gcgagcatct ctagctttaa tggctttgcg aactagatga gaagctactt ctccattttc
    58381 gagtaaaaag aaggttaatt tttcagaaac aatgctctct acaataggtc tcgctaaggg
    58441 acttcccaat ttgtctttgg tctgtccttc aaattgcaag tgctgctcag gaactaagat
    58501 agataatact gctgagagtc cttctcgata atctgagccc tctagatttt tatccttttc
    58561 ttttaagaga ttggttttac gagcatagtc attcatcgct ttggtaatag ctgactttag
    58621 tcccgtttca tggcttccac catctttggt gcgcacattg tttacaaagg ataagatatt
    58681 gtcggagaaa ccatcgttat actgcaaagc aacctcgact tgaaagtctt ggtcttgacc
    58741 ttccatgtaa ataacaggtg tcaaggtttc cttatcttca ttgaggtatt cgacgaaatc
    58801 ttgaacccca ttttcataat gaaactcttc aataatcggg tcatctccac gaagatctgt
    58861 caagctcatc ttgacatttt tcaaaagaaa agcagattct ttcaatcgtt ctgaaatggt
    58921 attgaactta aagtcaatag ttgaaaaaat cttatcatct ggcataaagg ttacaaccgt
    58981 tcctgattta gacttaggag ctgtgccaac ttttttaagg gttgtaacag gtttcccccc
    59041 attttcaaag cgctgacgat acactgaccc gtctcttgtg atttcgactt ctaaccaggc
    59101 agacaaagca ttgacaacag aggagccaac accgtgcaaa ccacctgacg ttttgtagcc
    59161 accctgacca aatttaccac ctgcatgaag aatcgtaaaa ataacttgaa cggtgggaat
    59221 ccccatggca tgctgacctg ttggcattcc acgtccgcta tctgccacac tgaccgagcc
    59281 atctttattg ataacaacct taatatcatc tccaaaacca gacaaggcct catcgacagc
    59341 attatcaaca atttcccaaa tcaggtggtg caatcccgta gcatctgttg aaccgatata
    59401 catccctgga cgcttgcgaa cagcatctaa cccttctagg acttggatag catcgtcatt
    59461 ataattatta attgtaattt ctttcttagt caacaccgac ctccagacag tttcatcttt
    59521 tttatcttac aagtttttta ccaattttgc aaaataattt gctaattttt tccgaattct
    59581 tttccagatc tagttctcca atctatgaat atgttataat aaggattatg aaattactac
    59641 tttttattac cattgcctat ttacttggtt ctattccaac tggactatgg attggacagt
    59701 acttttacca catcaactta cgagagcatg gatcaggaaa tactggaacc acaaatactt
    59761 ttcggatttt aggtgtcaag gcaggaacag ctaccttagc tattgatatg tttaaaggga
    59821 cactttcaat attgttacca attatttttg gtatgacttc aatttcatcc attgctatcg
    59881 gctttttcgc agttttaggg catacttttc ctatttttgc caactttaaa ggtggtaagg
    59941 ccgtagcaac aagtgctggt gtattgctag gctttgctcc gttatatctc ttttttttag
    60001 catctatctt tgttttagtt ctctatttat ttagcatgat atctttagct agtgtggttt
    60061 cagctatcgt tggtgtgtta tctgttttaa catttcctgc cattcatttt cttttaccaa
    60121 attatgacta ctttttaact tttattgtga tattacttgc gttcattatt attataagac
    60181 acaaagataa cattagtcgt atcaaacatc atactgaaaa tctaatacct tgggggctaa
    60241 atttaagcaa acaagtgcct aaaaaataaa tttactaaaa gcctgacttc ctctgaaagt
    60301 caagcttttt tgttttaact catttgttaa ttagggtaaa caacctctcc gtctgcaata
    60361 gtgtatttca cgacaccttt gagtttgtta ccaataaatg gggaattact agctttagaa
    60421 gcaaaattct cagtgatcag acgttcttgc ttgtctgcaa aaataaccaa atctgctgga
    60481 ccattttctg ccaaataacc cgcatcaaaa ccataaagca aagctggatt aagcgtcatt
    60541 ttttctaata gtgacataag tgtaagatga cctggttcaa ccaaatgcgt caaacctaat
    60601 gacaaagaag tttcaagtcc tgtcatacca gatggagctt tagtcatatc atcaacagct
    60661 ttttcatcct tgtgatgagg agcatgatca gtggcaatga ctgttataac acccgatttc
    60721 aagccttcta tgacagctaa gcgatctctt tgtgtacgaa ggggaggatt catcttggcg
    60781 ctggtaccta caatcaataa gagatcttca gttgttgaaa aatgttgtgg ggacacttca
    60841 gcagttacct tagcacccaa ctgctgagca aaagccacta cttgaaccga ttctgcttta
    60901 gataaatgtt ggatatgaac atgagcttgc ctgtcataag caatcatgac atctcttgca
    60961 atcatactat attctgctac accagttgcc ccacaaaaat gaaaatgctc ctcagcaata
    61021 ccttcattaa aaccaagaac cccatttaac tgaggatctt cctcatgcaa agaaatgaaa
    61081 gtttggttgg cattagccaa atcaaaggct tcttttaaaa ctttagaact ttctaaggga
    61141 ataccatcat ctgaaaagct tactgctcct gcttccaaca aagctttaaa atcagtcacg
    61201 tcttttccat taaaggcttg ggtgacactg gcattggtgt aaatatgaat cttttcttta
    61261 gctgcgctag ctaatacttc ctgtaaagtt tcgacatctg aaatgacagg attggtatta
    61321 gccatcatga caaccgtagt cacaccacct gatgctgctg ccaaggctcc cgtgtgaata
    61381 tcttctttgt gcgtttgacc gggttctcta aaatgcacat gaatatcgac caaacccgga
    61441 gcaacaataa gaccactagc atcaatcact tgagcttctt ggcattcaat agctgaagct
    61501 atctttacaa tctgtttacc atcaatcaag acatctgcca cttgatctct ctgcgatttc
    61561 gggtccataa cgcgtccatt tttgatgagt aacatgctct ctccttcttc tcacttatct
    61621 gtaaaactga tagacagacc tgtctgccaa taatactgaa actttgtcca taggctgctt
    61681 acctcaaacc atctgcctga taatcactaa tgcttgtcct attgtaacca atctatgcca
    61741 gtcatgcctt ctttttctaa aatagcattt gttcttgaaa agggtttgct gccaaaaaag
    61801 ccacgataag acgacaaagg gcttggatga ggactctcga tgatgtggtg ctttggatta
    61861 gtaatgaagg cttttttctt ccttgcataa gctccccaca aaatgaaaac tacagggctg
    61921 tctttctcat tcagcacttt aataacagcg tctgtaaatg gctcccatat taagcctgca
    61981 tgcccattag cctggcctgc tggcactgtt aagcaagcat tcaaaagcag aaccccttga
    62041 ctagcccaag tgcttaaatc atgatggtca cgaggaccaa tgtcatctgc taattctttt
    62101 aaaatattaa taagggatgg cggagcagaa atctcttctg gaactgaaaa tgataagccc
    62161 tgggcctgtt tggggccatg ataagggtct tgtcctaaaa tcaacacttt ggtttcttcc
    62221 aaaggagtga cttgtaaggc tttaaagaca ttttctcgtg gaggatagac aagaccggaa
    62281 gcataggctt catctaaaaa gtgattgatg cgaccgtagt aatgctccgg caaaaatgat
    62341 ttgattttct catgccaaat tgaatgagcc ataagattcc tttctaatca cgtcagtttc
    62401 taagttaaat acgatgtcct tttctatcta gtttaccaca ttttaaatag aaagaccctg
    62461 aaaatatgat atttccaggg ttaatattcg ttttttacag gatattaaac aagtgctagc
    62521 ttattttcta agaattcttg gtaacgttct aacaaaaaag caataatcca atagataaag
    62581 gctactaaaa tgtacatgga catgtagtcc cactccctac caccgataat tttggcattt
    62641 tgaaaaatat ctggtacggt aatcatggca gctagcgacg aacttttaac catatcaata
    62701 atgacattgc ctagaggagg aactgcaatt cgaaaggctt gaggaagaat aattttctta
    62761 accataagag catatggcaa ccctaaagcc ttagctgctt cccactgtcc cttgtcaata
    62821 gcttctatag aagagcgaaa aacttcagaa atataggcag cgctaaccat agaaaaacca
    62881 agataagcgc aaagtaaagc tggcaattct aaaccataat aaggcaaccc gaaataaaga
    62941 acaaagagca ccacgatcat cggcacacct cgcataatag agatgtaggc cctaacaaga
    63001 tagtgtagca gtggctgatg tgaccttcct agtagggcaa ggagcaaacc aaagaccagc
    63061 cccgttaaaa agctaagcaa cgatatgcca agggtataag gtaatcccga taatacaaat
    63121 cctaaactat ctttcattaa tgggatatta atcatgtggt taggactcct ttaacatcaa
    63181 gtattagtta acgtctttcg tatcaatgat gggaattttt ttgtctttgc caaaaggttt
    63241 tgtcaaatct tgaccagcat agtaggtttc agatattttc ttcaagctac catcttttat
    63301 catgtcttta ataacagcat ctattttttt cttgaggcta tcgtcttttt tgttcataac
    63361 aattccttgt tcggttgggt tgtactgagc atcgctcatt ttgacattta gatttggatt
    63421 ttgagataac atgtaatcca caaataattt ttgagctggg taatcatttg gaatgaaatc
    63481 tgttcgaccg ttagccacat cgtttagata aacatctcct gtaacattat cgtaggtcac
    63541 cagttcagct ccctgttttt gcgctacttt catgtactct gttccagaag cgccagctgc
    63601 tttttttcct ttccagtcgc taagatcttt tttagccatg tttgagctgc catcagcacg
    63661 gacaatcatg cctcctaccc cgtatttata aggcgtagag atattgtatt ttttctgacg
    63721 ttttggggta atgtcaaagt tgttcaaaga aatatccact cgaccactat caactgaggt
    63781 aaaggcttgg tcaaatcctg tttcaacaaa cttgacttta atgttaagtc gtttaccgat
    63841 ttccttgacc atatctactt cgtaacctac taactcatta ttatcgttgt aaaaagaagt
    63901 tggctgatag gttcctgggg tagctacttt taacacccct ttttctttga tagtctccca
    63961 acttgatttt tgagatttat gtggcgcaca tgctgccaat aaaaggctgg caagtccgat
    64021 agacagtaaa gtaactgatt tcttcatagt aactccttta ttaagataag aatagtataa
    64081 cattttgatt aagttgtgtt atcagtgagc gctcaatctc tttaaaaagt taatctataa
    64141 tagttaaact gttttataag attattattg aggaatcttc aataatcctg ctgcctcaaa
    64201 ctgctctgca attcctaata ataggtcctc tctacctttg gctgcaatta gttgaatgcc
    64261 cattgggagc ccttccttag tttcgtaagt aggtaaacta atagctggct ggccagttag
    64321 attaggcaga gctgtgtaag gattaatagc cagactctta ccaaacatgg tttcgaccaa
    64381 attgaattgc tcttcactgc tgaaaatttc agcttgagcc aagttagcca tgagtttcga
    64441 atctgggaca agttctccgt gcttaggagc tggtgtgttg gttgtgaacg tcaacaacag
    64501 gtcataagtc tcatgaaaac tagccatggt tgcactgtac gtatcccatt tttgaaggac
    64561 ctgtgagtaa cgccaagctg ggatgtcttt acctgattgg taaatagccc aggtcatggt
    64621 ttccatatcg tctttggtca tcggacgtcc aaaagtgtct tcaatatcag caaacatagc
    64681 agccgtttcc acactattca taatataata atgacgaatc acttctgtca tatttacagg
    64741 aaactcttcc aattcaacta gctgatgccc ttgttctctt aaccaagtta ctgcttgtct
    64801 taaagctttt tcagtatcta aagatactgg gctaccatca cttaaccgtt gataaaaagc
    64861 aattgtcaag ggacgttgta gcgattgata aatactattt tttgttaagg tggctagggg
    64921 gaaggggctt tccatttgtt ccatctgtaa atagtagagt agatttctag tatctctaac
    64981 ggatttggtc aaggcaaaat gaactgaggc tccttgccag cttcgataag aaccaggtcc
    65041 gacaggcatg cgcccgcggc taggtttgag cccaattaag ccattaaacg aggctggaat
    65101 tcgaatagaa ccaccaccat cactagcagt tgctagtgca ctaattcctg atgacactag
    65161 agcagcagct cccccagatg agccaccagc atttcgtgta ttatcatgag gtaatgaaac
    65221 cgggccatgg agctgactat cactaatatt tttaaagcca aattcaggtg tgttagaacg
    65281 ccctaaaata ataaatccca agtcttctaa ccttttcacg aataaatctg ttttagtcgc
    65341 atgatgattc ttgaatagct tagaacccga tgttgataag tctcccttca attcttgtcc
    65401 caaatctttc aaaaaaatgg gaactcctgc aaaaagctta cctgaaaaat ccctttgttt
    65461 ggcttcttct agggctgctt caaagcgttc tgaggtaata gcatttaagg tagggttcaa
    65521 ctttttagcc ttataaatag cctgggttac taattctagt ggtgtggtct gaccggtctg
    65581 aacagcaata gccatagccg tcgcatcttg ataagtcata gctactcttc ctttctaaga
    65641 tatgaatcct aaaacattct tttttattaa aacacaaata aaagaaaacc accattaaaa
    65701 ggttagaaat tagaatgtga tgtgtaagga atgtagacaa aacaatcaaa acataacatt
    65761 ttgaattggg gttaaagaga ttttttcatt aaaaataaac ctggctgata gttccttatt
    65821 gttgccagtt tacctggtct tctttaaatt ttttaagtaa atgtaaacca tcattagtaa
    65881 tatagccttg caactttgca actgcaatta gctcagtata attagaaagc gtaatcaact
    65941 tgataccagc ttctttaaaa ttctgactag cttttggtaa ctcataagtg aaaatcgcaa
    66001 caactcccag aacgtcagct ccctcacgac tggctgctgc ggctgcatct agtaccgaac
    66061 cacctgttga aatcaaatct tcaatgataa ccattttttg gcctttaagc acacgcccct
    66121 caatctggtt gcctgctcca tgatcttttg gcttactgcg aatataagca aaaggaagag
    66181 tcattttatc tgctataatg gcaccgtgag gaatacctgc tgtagctgta ccagcgatga
    66241 cctcaacttc tgggaaatga gccctgatag tttccacaaa cccattctca attaaatcac
    66301 gagtcttagg ataagaaagg gtgacacgat tatcagtgta aataggtgat ttaatgccag
    66361 atgcccacgt aaaaggatct tcaggcttta aataaacagc tttaatatca agtaattgag
    66421 ttgcaatttg gcttcctagt gtcatttctt attctccttt ttcttcttta acagacaagt
    66481 gttggtttcc taatcttatc tgttagcctg cccactcagc ttttatggct tggtaagcag
    66541 ccactgggtc ttttgcctgg gtaattggtc gccctaccac aatataatca cttccaatgc
    66601 gtcttgcttg gtttggagtc atcactcgtt tttgatcgcc aatattactg cctttaggac
    66661 gaatgccagg aattaagcaa gtaaatcccg taggcgtcac cgccttgata gcttctactt
    66721 cttgtgccga acaaaccacc ccatctagct gagctttagc tgcccccttg ctgtaatgca
    66781 aaacagactc taaaagactc gtttgaatat tttgatcacc acgcatttgg tcttcactgg
    66841 ttgaagttag ctgcgttacc gcaattaagg tagggccttg gcctagtcct tctcgagctg
    66901 cttttagcat ctctacacca ccagctgcat gaacagttgc catatcaata tctaattctt
    66961 taagaactgc catagcagca cgaacagtat ttggaatatc atgtaatttt aaatccaaaa
    67021 atacattatg ccctaacgat ttgatagacc gaacaatatc tggtccttgc gcataatata
    67081 attccatacc aattttcacg tatagttttt cttctgctgg aaataagtct aaaaatgctt
    67141 tagtctcctc aaatgatgaa aagtctaaag caataattgg gcgttcttct ttcataactt
    67201 atcctttcta taatgtgtca atatctcatt aagcaccaaa aagcctcgct accaaagaag
    67261 cgaggctaca gcaaactaaa agggaattcc ctttttttat cttgtatacc ttgtttgcct
    67321 ctctggactc acttaaaggt gtctaaattt aaactattat agctttttta aaacaagatg
    67381 tcaaaacttt ttgttatttg aacacatttt tcctactata tctttttttg tacacttacg
    67441 tcaactcatt ttatcatttt tacccaatca tttattcaaa ctcacctgtg ggtaccttag
    67501 ggctttggta atattttata aaagcttctt cttcaagatt aaccctctgg atatgttcat
    67561 agagcacatc cggaatagga gcttccttaa gtgacaaagc actcactttt aaagatgaaa
    67621 aaacatcact taagacccca aaaactcgaa tgcgtttatc tccaataata atttgaaaga
    67681 cttctttgga ctggcataaa tctatcagat gatccactcc tttaatccaa ttatcgacaa
    67741 tatccaaagt tttgttcatc aacttaaaag ctgattcttc ataccaaaag gtagactcaa
    67801 tcaagcgttg ctgcatatcc aaggtatcaa tggccgcaac aatatctccc aactcagact
    67861 gtactaaatg agctggaaat tcccctccaa gtatagaagg agttcgttct acaagcttca
    67921 gttcatctcg aaaaagagtc aaatagtgga tactgaccaa taacttttgg attaagattt
    67981 gatgactatt ttgttcagta acattcacac gaccaccacc ctttgattag aaaaatacct
    68041 atttgttaat actattaata taacacaaga aaaataaaag ggcaatgaaa ttgatagatt
    68101 caactctcaa aattgaatca tatttatcct aggccatatc gagaaaagac tccagcgctt
    68161 tttcaaagtt ctaaacccat gatgacgttt gtgcttgcgt ctttattttt tttgagctag
    68221 actgtactta tgagaattca acaactgcat tatattatca aaattgttga gtgcggctct
    68281 atgaatgaag ctgctaagca attatttatc acacaaccaa gtctatccaa tgcggtcaag
    68341 gatttggaaa tggagatggg cattaccatt ttcaaccgaa atcctaaagg gatcaccttg
    68401 acaaaagatg gggtggaatt tttatcttat gctcgccaaa ttatagagca aacatcactg
    68461 ttagaagacc gctataaaaa ccacaatact ggccgagagc tctttagcgt ttcatctcaa
    68521 cattatgcct tcgtagtcaa tgcatttgtc tcactcctca agcggaccga catgactcgg
    68581 tacgaactct ttttgcgtga gacaagaact tgggaaatca ttgatgatgt caaaaacttt
    68641 cgatctgaaa ttggtgttct ctttatcaac gactataacc gagatgtctt gaccaaatta
    68701 tttgatgaca atcatttgac tgcctctcca ttatttaagg cacagcctca tatttttgtc
    68761 agcaaatcaa atcctctagc aactaaaagc ctattaaaca tggacgactt gagagatttt
    68821 ccttacctga gctatgacca agggattcac aactcctttt atttttcaga agagatgatg
    68881 tcccagatgc cccatagcaa atcaattgtg gtcagtgacc gtgccaccct ctttaactta
    68941 atgattggtt tagatggcta caccgttgcc agtggtattc taaatagcaa tctaaatggt
    69001 gaccagattg tggctatccc gctagatgtc cctgacgaaa ttgacattgt ttttatcaag
    69061 catgaaaaag ccaacttgtc caaaatgggg gaacgtttta tcgaatacct tctcgaagaa
    69121 gtaacctttg attaatttct ttttcaatcg tcacactaaa aaacacggta gtaagacctg
    69181 tatcggtcaa gttatcgtgt tttttgataa atatcagaca atagattgtc tccaaaggcc
    69241 caactccgtt ttaataatgg cattcatgtc atcaaagtaa aaaggttcac gtcggtagat
    69301 tacaccagaa aaagtcgcca aggtgataat gttttccaaa aaagcctgtg aagaaaaatg
    69361 agtggtgcga tgcagttcct cttcatcaaa aggcttaatc aaatgagcca gaggattacg
    69421 gacagccttt tcaaaatgtc gtaacaaaaa aaccaagtcc ttgatttcct gaggtaagga
    69481 ggtcaacgtc aacatgtctg ctaagctttt ggtcgtcaca ttgcgagact gcttttgaga
    69541 caggtaagcc ttaaaaacct cgtgatcaga ttccaacatg gcctgaaaat gccaggtatc
    69601 atattggtca ttctttgtat caaaaatata agccttgaag tttggaattt ctgacgtgat
    69661 tagtctgaga aaaagtcggt aaagaatagg cgacactgac ctgacgaaat caataatagc
    69721 accgtttttt actttaactt ctaaatccaa aatgtaattg gcaatctgct catcttcaag
    69781 cgattggtta agccataatg aacagtggta ctggtcttca atgatccgat tctctgctgc
    69841 atgttccgcc agaaaggcaa ggttcaattc tctgcgctct tttaacatct ctagtaaata
    69901 gagggcagtt ttagggatat ttggcaaggc tttagcaatt ctaaaggcgt gattataagc
    69961 atagacatcc aaaaggatgt ctagtgtttg attattagtc attggcaatt aaggtttcca
    70021 aggcgacctt catcatatca gtgaaagtgg tttggcgctc ttcagctgta gtatcttcgg
    70081 ttggatcatt caagttatct gagatcgtca tgattccaag ggctttgaca tggtgctgag
    70141 cagctaaata gtaaagagct gctgcttcca tttcgatggc tttaacaccc aatttaccaa
    70201 gagccatatt acgctcaggc atgttagtgt aaaagacatc agaagaaagc acattcccaa
    70261 cgtgagttgt tactcccatt tctctggcga tatggtaagc cttgtcaagt aaaccaaaat
    70321 cagcaatttg tgggaaatca aattctggga agtcattacg gataatattt gagttggttg
    70381 ctgctgcttg ggcaagcacc aattcacgca catgaacttc tgggtcaatc gcacccgcag
    70441 taccaacacg gatcaatgtt ttgacaccgt aatcaacgat taattcacga gcatagatag
    70501 agatcgaagg catccccata ccagttccca tgacagaaac gcggcgccct ttgtaagttc
    70561 ctgtgtagcc aaacatgtta cgcacttcgt taaaacacac tgcatcttct aggaaatttt
    70621 cagcgataaa tttcgcgcgc aaagggtctc caggtagaag aattttatca gcaatatcac
    70681 cttttttggc agaaatatgg atagacatta ttaagatatt aaaggcgaca aagaacaaag
    70741 taaaaatagg aaactgacga cgcatcccag atgctagaca gtttatcttt tttacacagt
    70801 tctccgcccg tattcaattc aatgaataca gttagcccta cctttccttt tattttgtag
    70861 aaggtcagag ggcggacaga aagcaactga aatttaggga actaacgcca tgtgtgagca
    70921 caaaagttag tttatctagt ttccgagctt tccgcccgta ttcaattgaa tacaacccca
    70981 ttcctttcat aattgatatt gaatagaaga agagagctaa aaatcgagtt caaataagaa
    71041 aggactaact ctctttcctt tattatttaa aaattaatac gaagaaatat tcgagtccat
    71101 gcttaattta aaccgaatac gtctctttcc cttcgttggt tatgttagtt agaaaagcta
    71161 gaatctgagt tcaacattca tggaactcac accccgtgat tattttttga tttttttatt
    71221 gcgaacagat gtgccaaact gacgacataa aataacattc ctgtaataat gctccagttg
    71281 attttgttcg tcctacaact cagctaaaat agctttaaca agacctttga aatcttcttt
    71341 aatatgttca gtcacttcaa caacttcttc gtggttcaat tctgattgga aaccagctgc
    71401 aaagttagtg atggctgaaa tgccaagtac tttaagtcca gaatgagcag ccacaataac
    71461 ttctggcaca gttgacatgc cgacagcatc tgctcctaat actttgaaag cacggatttc
    71521 tgctggtgtc tcataagttg gaccagttaa gcccatataa acaccatctt ctagtttgat
    71581 gttcattttt tcagccactt catgtgcctt attgcgataa accttagtat aggcatcaga
    71641 catatcaggg aagcgtggac caaactcgtc caagttttca ccgattagtg ggttatttcc
    71701 ggtcatattg atatggtctg tgattgccat caaggtacct gggccgtagc cgataccacc
    71761 agctgcattt gtgacaagaa caccttcaca tcccagagct ttcatgacac gaacagggaa
    71821 agtcaccact tcaagcgggt ttccttcgta aaaatggaaa cgaccttgta gggcaagtac
    71881 tttacgacca gctaaatcac cgtagactaa ttttccagca tggccaacaa ctgttgattt
    71941 gccccagttt ggaatatctg cataatcaat aacaacagga ttctctactt cttcagcaag
    72001 ttcaccaagt cctgaaccca gaattaatcc aaattctgga gcttcaattc ctttagcaac
    72061 taaaaagtct tttgtttcgt taattttagt catcaatgac atctttttct ccttttacct
    72121 caatagggtt cacaatctcg ccatcctctt taatataagg actaggcagg ggaacaggaa
    72181 gaatatccag taaggtctca gaaggacggc aaagttttac tcctttgcga gtcacaacaa
    72241 taggacgatt gatcaaaatt ggatccgtca acatggcatt aataacgtct ttctcagcta
    72301 ctgcttgatt tgctaatcca tgagcctcaa attcaggaac attggttcgc aagagttctc
    72361 gcgcagagat tcccatcgat tgtaagagct caattaaagt ctcccgatta ggtggcgtct
    72421 gcaaatactc aataatagta ggctcaatac ctgcatggcg aatcatggca agaacattac
    72481 gtgaagtgcc acagtttgga ttatgataaa tcgtgatttc ttccattatc aactaatttt
    72541 cttattttaa gtgaccaagg aatgactccc caatcatggc tatatcaact ccaaaatttt
    72601 ctgcaacagt cgctgaaata tctgcaaaat gcccttgtgg aataagacca tttccagtaa
    72661 aggatgcaga gtaggcaagc aatggaatgt attcacgagt gtggtcggtg cctgcatagg
    72721 ttgggtcatt accatggtca gcagtgatga gaagcaaatc gtcttctttc atatttgcga
    72781 tgatttcagg taggcgattg tcaaattcat gcaagcagtc gcgataaccc tctgggtcac
    72841 gacgatgacc aaagttggca tcaaaatcaa cgaggttagt aaaggagaat cccttagtaa
    72901 actcaggtaa ttgaagagtc ttaataagcg tgtcaatacc atggctgttc gacttattgt
    72961 gtcccatgtc gtttgtaata cctgaaccat taaagatgtc attaatctta ccaacggcat
    73021 aagttgggac acctgcgtca gccagtttgt tcaaaacggt atcttggaaa ggagacactg
    73081 catagtcatg acggttagcc gtacgtgtaa agtttcctgg ttcgcctaca taaggacgcg
    73141 caataatacg gcctaaaagg gcagggcgtt caagcgtgat ggagcgagca tattcacaaa
    73201 tcttgtaaag ctcttccaca ggaataatgt cttcatgggc tgcaatttga agcactgggt
    73261 ctgctgaggt gtaaacaatc aactcacctg tttccatttg acgcgaacca aaatcatcaa
    73321 taaccgcagt tcctgaatag ggtttattag cttcacgaat aattttgcga cctgagaatt
    73381 cttcaatctt agttaaaatc tcttctggga aaccattcca gaaagtgtca aaaggttctg
    73441 taatgttcaa acccataatt tcccaatggc ctgtcatggt atcttttcca agagatactt
    73501 cttccaattt ggtcacgtaa ccagtaggat tatcttctgt tggaacagtt tttagtggta
    73561 ttggacgaga aatgtttcca agtccaattt ttgccatatt tggaaccgat aagcctgctg
    73621 tttctgaaat atgaccgagg gtgtcagaat ctgtatcagc tacaccagca ttaaagaatt
    73681 tgtcagcatc tggtgctgca ccaataccga cagagtctaa aacaaccaag tgaatacgat
    73741 taaattttga cataagtctc caatctaggg gaggttacgg ttgactcccc aatacctata
    73801 aaatacatta acactgttat atgctaagac tagcttgctt taggcacttc taaaacagta
    73861 acgccgtctt tactagcaac aatcacctta tcaaccatac cattaaagag accgtgttcc
    73921 acaacaccaa ctgttccatc taacaggtga ccaaaagcaa caggatcttt aatacaaccc
    73981 aaatcaagat caataatata gttttgcatg tctgtcacca aacgactatc acctttcata
    74041 cgaaaagacg gtttgtaacc agctttttca aagacacgga acaaacgatc agcaccatat
    74101 tgaacgactt cgactggtaa cttaaaggca cccagatgtt ctaccatttt agaagcatca
    74161 acaacccaga tgtattcttt tgttggtgtt gcaacaattt tttccattag taaggctgcg
    74221 ccgccaccct tgattccatt gaaatcctta tccacttcat cagcaccatc tacggtgagg
    74281 tcaatgctat caatatcatc tatcgatttt aaaggaatgc ctaagacttc tgcttgcttg
    74341 ctagtcacac ttgacgtagt cacaccaacc acttgcagtc cttcttgctt tacgcgacgg
    74401 ccaatttcct caacaaaata gtaagccgtt gacccagttc caagcccaat ggtcatgcca
    74461 tcagtcacat attgcgcagc ggtaacaccg gcaatttttt tgagtgcttc catgattccc
    74521 ccttataata gaattgcgtc ttagcacttt attataccat gaaagcgcca acttgttaat
    74581 gaaaacattt gtttttctct cattgacagc ctaagtgcta tagaatagga tgatcttttt
    74641 aaaacttatg atttattcta aagtcatcat ataagcactt acttttcgtg tttatttagc
    74701 tttttgaaaa tcaagtgttt ttgtttgacc tttactgacc ttttggttat aataatacta
    74761 taagatgagt aaaaataatg tctgaatcat tttattagca aagggtttcc tatcatgtga
    74821 aatcctaaca acgattctgc gactgcttac aaacatctta tagtctattt tttattgcga
    74881 ggtaactgat atgacacatt tttctggtaa agatcctttt gtaaatatgg atgatatttt
    74941 caaccaatta atggcaaaca tgggtggtta tcgtagcgaa aatccccgct atctcgttaa
    75001 cggtcgcgaa ataactcccg aagaattcca acactatcgt caaacaggac aactccctgt
    75061 agcgacaacc aaagcaacaa cttctcaaat gttaacacct aaagctgata gtgtattgac
    75121 tcaactcgga actaacttaa cacaagaagc tcgtcaaggg catcttgacc ccgtcattgg
    75181 tcgtaacaaa gaaattcaag ataccgctga aatcttggca cgacgaacta aaaataatcc
    75241 tgtccttgtc ggagatgctg gtgtcggtaa aactgcagtc attgaaggtt tagctcaagc
    75301 cattgttaat ggagatgtcc cagctgctat taaaaacaag gaaatcgtat caattgatat
    75361 ttctagtctt gaagctggta cacagtatcg tggttccttt gaagagacca ttcaaaactt
    75421 gattcaagaa gtaaaagaag ctgggaatat catcttattt tttgatgaaa ttcatcaaat
    75481 agttggtgct ggtgccacaa gcagtgattc aggctcaaag ggacttgcag atattcttaa
    75541 accagccttg tcacgaggag aattaacact gattggtgct actactcaag acgaataccg
    75601 caatactatt ttaaaaaatg ctgcactcgc tcgtcgcttt aatgaagtta aagtgaatgc
    75661 accatcagct gaagatactt ttcacatttt aatgggtatt cgtaatcttt atgaacaaca
    75721 ccaccatatt acccttcctg ataatgttct aaaagctgct gttgattatt ctattcaata
    75781 catcccacag cgtagcctgc cagataaagc aattgactta ctggatatga cagctgctca
    75841 tttagctgcg caacacccgg tcactgactt aaaaacactc gaaactgaaa tagctaaaca
    75901 aaaagagagg caagaaaaag ctgtcgccaa agaagacttt gaaaaagctt tagcagcaaa
    75961 aacacggatt gaaacattac aaaagcaaat tgagcaacat aaccaaagcc aaaatgttac
    76021 tgctacagtc aatgatatcg cagagtctgt agagcgctta actggtattc ccgtctctaa
    76081 catggggact aatgatttag aaaggctcaa aggaattagc agccgcttaa aaagccatgt
    76141 catcggacaa gatgaggctg ttgcagcagt agcacgtgct attcgacgaa atcgagcagg
    76201 ttttgatgat ggtaaccgtc caataggttc tttccttttt gtgggtccaa ctggtgttgg
    76261 taaaacagag ttagctaaac aattagcact tgatttattt ggttccaaag atgctattat
    76321 tcgacttgat atgtccgaat ataacgatcg cactgctgtg tcaaaattga ttgggacaac
    76381 ggctggttat gttggctacg atgataataa taatacccta actgagcgtg ttcgtcgtaa
    76441 cccttatgct attgtcttac tagatgaaat tgaaaaagct gatcctcaaa tcattacact
    76501 tcttctacaa gtgttagatg atggacgatt gacagatgga caaggaaata ctattaactt
    76561 taaaaatacc gttattattg ctacatcaaa tgccggtttt ggccaacaag atacggaaac
    76621 ttctgggttt aacattatgg atcgcattgc accttatttc agaccagagt ttttgaaccg
    76681 ttttaatagt atcattaaat ttaatcatct gcaaaaagaa aatttagaag aaattgttga
    76741 tttaatgcta gctgaagtaa atcaaaccac cgcaaaaaaa ggtattagtt taacgattgc
    76801 tgatgacgct aaagctcatt tgatagattt agggtacaat cacgctatgg gagctcgtcc
    76861 attacgacgt attatcgaac aggaaattcg tgaccgtata actgattatt atcttgacca
    76921 tccagaagtc aaaaaacttc aggcaatcct agaagaagga caactagtga ttaggcaaaa
    76981 agatcagtaa taaacttctt caattgaata attttcaaaa catgaaaaaa tccgtcttgt
    77041 gactacgtta tacacttgac ggactttttt ttagcgcttt tttaaaaata attttttcat
    77101 cgcctaataa ctcaagtttc tttccaaatc tggtgtaatc aaaataacca ttaggtgtga
    77161 gcaatccttt tgaaaaagaa gtatgtcccg ctgctacttc ttctttgata tcaatggtgt
    77221 gcaaaatacg attaactttt cctttgagaa caacagcaga taaatgtcct gttttttgat
    77281 tatatttgcc tccgatctga gaagctaatt tctcaaaagc ttgatctaaa atcatttcta
    77341 attcatggct agctggcata ctattctcaa taatttggcg ttctttacta ctcaagtcac
    77401 caacaactaa atgattttcc tttaatgtct ttaataattc attttggtga taagcagcta
    77461 aacgtttgac aaaaatgtct cgttcaactt gaacactaaa actcaagtca acgttgttat
    77521 ttttaactgt tagtatcatc tgagatgacg ttaataaact atcatcaata agagggctct
    77581 gatgcaaacc agtaagacgt ttagcaaaat catcgcctaa cttctgatca atgcttgttg
    77641 ttcgccagat accttcaata gagctattac gatatcgaac accaaaaagt acagcaagca
    77701 agataagaaa aataataaat acaaaaaggg cattgcattg atggcataac aatgactttc
    77761 ctttagagcg cccttgggct acttgtgtca tgactcatct ccttaatata aaatactagc
    77821 atgtcatcat taaggcgtca agtaaaatcg gtaaacctaa ctatgatttt ttatgttttc
    77881 gataagaaaa acaccctcta ctgagaatgt tttagcatag ataaatcaac acctatcgct
    77941 agacctgctc taaaatagca tcccaagaat catcgatacc aatacgttct accgaagaaa
    78001 atactataaa agtatcagag ttgtcaaaat tcaaagcttt cttgaccaca gactcatgtt
    78061 tgttccattt gccacgagga atcttatctg ctttggttgc cacaacaata acaggaatgt
    78121 catagtactt caaaaagtca tacatctgaa tatcttcttt tgaaggggca tgacgtaaat
    78181 caaccaaact cacgactgca cgcagattgt ctctgctggt taagtattct tcgatcatct
    78241 ttccccattt ggcccgttca cttttagaaa ccttggcata gccataacca gggacatcca
    78301 caaatctaag cttgtcatca atattgaaaa aatttaatag ttgggttttt cctggcttgc
    78361 ttgaggttct tgccaaattt ttgcgcccca atatggtatt aataaaactt gatttaccaa
    78421 catttgaacg tccagcgagg gcaatttctg gcaaatcatc tttggggtaa tgagatttat
    78481 tggcagcact caataaaatt gaggcgttat gggtatttaa gacttgttct tcagccatta
    78541 tttctcctta agctgtctct aaaacgggtt ttgacttgcc ttcgacagca gccttggtga
    78601 tacgcacttt tgtgacatct tcttggcttg gaatttcaaa cataatgtct aacatcgttt
    78661 cttcaataat agaacgaaga ccacgtgctc ctgtcttacg ctcaatggct ttattggcaa
    78721 tggcttctaa ggcttcctta tcaaatgcca attcgacgcc atcgtaagaa agaagggcct
    78781 gatattgctt gaccagggca tttcttggtt ctgtcaaaat ttgaatcaaa tctgatgtgt
    78841 ttagttgttc aagggctgcc acaactggta agcggccaat aaattctgga ataagcccaa
    78901 acttttgaat atcttctgaa ataatttctt gcatataaga agcattgtca tcaattttac
    78961 ggctgttttg accaaaacca ataacttttt cacctaaacg ttgtttaaca atctcctcga
    79021 tgccatcaaa agccccgcca acaataaaca agatattttt tgtatcaatt tggatcattt
    79081 cttgattagg gtgcttccgc ccaccttgtg ggggaacact tgctaccgta ccttcaataa
    79141 ttttaagaag ggcttgctgt acaccttcac cagatacatc acgtgtgata gatacgttct
    79201 cacctttttt agcaatctta tctatttcat caacataaat aataccacgc tctgctcgtt
    79261 cgacattata gtcagcagcc tgaatcagtt tgagtaaaat attttccaca tcttctccaa
    79321 cataccctgc ttcagtcaaa gaagttgcat ctgcaatagc aaatggtaca ttgaggcttt
    79381 tagccagagt ttgtgctaag aaggtttttc ctgaacctgt tggtccaatc atcaaaatgt
    79441 tggacttttg taaatccaca tcatcgtcat cacgactttc tgtaaacgag acacgcttat
    79501 aatgattgta cacagcaact gataaagcac gtttagcacg atcttgacca accacatatt
    79561 gatttaaaac atcaaggagc tcttttggtt ttggaacttc tgtcaaatcg gcaaggactt
    79621 cttcagccaa ttcttctttt ataatttctt gtgataaagc tacgcattca ttgcagatga
    79681 aaacattatt tcctgcgata atttttttaa cgtcatcctg gcttttacca caaaatgaac
    79741 agtatacttt aatatcgtta gttctacttc ctgccatttc ttataattct cttactttct
    79801 cttatctttt actgaatttt aatattagtc aatgtgttgt attagttttt agtgattctt
    79861 gcttgatagc taaatcttca ccagtgctgt cttcgcaagt cacatctcaa aacaatgtac
    79921 catagaaggc gtgaatacta ttaaccagat tagtaaacgc atttaataag aacagacttc
    79981 ctaagccata acgattcttt ttaaaagctg ggatggcaca aagaacacaa atcacgcaca
    80041 aaaaagccgt aaatactcca aaaatactac gttgcatcgc ttatcatctc ctcagactat
    80101 ttgtgtttta aagcagtaac ggtaaaatca taaggatttt tagcgtctcg agcatagaac
    80161 gtttggcttt cttgcgtgaa atgactaaaa tctagatttg gtcggtaggt atctccttta
    80221 aaacgatgat ggataactgt ttttatgata cgatcgaaat aaccattaaa cgcttctaaa
    80281 accttattcc caccaatgat ataaagtgtt ttatcctgcg catggtacca ctccaagact
    80341 ttttcaatac tagtcattgt caacacctca tctacttgat aatctctatt tcttgtcatg
    80401 acaagggttt gacgttgagg aagtcttttg caattcattc cttcaaaagt cacacggccc
    80461 attaagactg cttgatgtag cgttgtcttt ttaaaatgtt ctaactcttt tggtaaatac
    80521 catggtaact tacccgcaac accaataagc cctgcttcat cctctgccca aatagcaata
    80581 atttcctttg tcattaatta tttccttcat tttaaactct atttatttta ccaaatttat
    80641 gaacaaaatg ctcacaaaaa atctaaataa agtttaaata gcaaggtcaa agtgcaactg
    80701 aggcttcact ggatcataat tttgtaattc aaaatcatct ggtttaatat caaagaaatt
    80761 agtcccatct ggaacattta aaacaagctt aggctgacta gcaactggct gtcgctttag
    80821 taattcttga gcctgatcaa attggttgtc ataaatatgt aaattgttaa caaaataaaa
    80881 gaacttacct attttccatc caaaatgttt agcaatcatc atctgcaaag caacgtattg
    80941 catggcattg atgtgatgag caactaatat gtcattagaa cgttgcgtca aactagcatc
    81001 taaataaaga tcttccccta cacgtctaac atcaaacatg atttgaaagg cacatggcaa
    81061 caaccctttt gtctcctcaa atgcttcata gtcccagaga gaaatgacat tacgacgatt
    81121 ccaaggattt tctgctaatt gctttagtat ttttgagatg atatcatgtt ttttgactac
    81181 agcaccataa cgttgcccaa tagtacgtgt ctggtcaact tcccattcat tccaataatg
    81241 aacattatat ttagcttcta gcacatctaa actgttggac tgatcttgat atatccaaaa
    81301 taattccttt atagcagatt taattggaat gggtcgtaaa gttgtgatgg gaaactctcc
    81361 tttagctaaa tcatattcag caaacgcccc agtaatatac ttagaatgag ctgttcgacc
    81421 atctttatat ttaggacgtg cttgctcact caatgatcct tcgtttataa ttttttgaat
    81481 attagcttta aaaatctggt cagcttttgt catctctaat aacctttctg
//
LOCUS       DATWVB010000005        65098 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.005, whole genome shotgun sequence.
ACCESSION   DATWVB010000005 DATWVB010000000
VERSION     DATWVB010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65098
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.005"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            113..1309
                     /gene="tuf"
                     /locus_tag="VCX65_000358"
     CDS             113..1309
                     /gene="tuf"
                     /locus_tag="VCX65_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEP5052849.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            1550..2308
                     /locus_tag="VCX65_000359"
     CDS             1550..2308
                     /locus_tag="VCX65_000359"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEP5052850.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(2407..3642)
                     /locus_tag="VCX65_000360"
     CDS             complement(2407..3642)
                     /locus_tag="VCX65_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEP5052851.1"
                     /translation="MALIEISQEQFDHYCHSLVHHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQNDVIELI
                     LKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(3629..4855)
                     /locus_tag="VCX65_000361"
     CDS             complement(3629..4855)
                     /locus_tag="VCX65_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEP5052852.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWRKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRAL
                     FVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGIEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLDIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLAAGKTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            complement(4855..5664)
                     /gene="yidA"
                     /locus_tag="VCX65_000362"
     CDS             complement(4855..5664)
                     /gene="yidA"
                     /locus_tag="VCX65_000362"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEP5052853.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHMVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            complement(6120..7421)
                     /locus_tag="VCX65_000363"
     CDS             complement(6120..7421)
                     /locus_tag="VCX65_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEP5052854.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEVLFHTDHEAFTQEIITNPETEINAILVRHALDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSRGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMIQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            7503..7889
                     /locus_tag="VCX65_000364"
     CDS             7503..7889
                     /locus_tag="VCX65_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEP5052855.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            8119..10800
                     /locus_tag="VCX65_000365"
     CDS             8119..10800
                     /locus_tag="VCX65_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEP5052856.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGTLQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVQFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(10884..11879)
                     /locus_tag="VCX65_000366"
     CDS             complement(10884..11879)
                     /locus_tag="VCX65_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP5052857.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRIKSTI
                     EATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(11943..13850)
                     /locus_tag="VCX65_000367"
     CDS             complement(11943..13850)
                     /locus_tag="VCX65_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEP5052858.1"
                     /translation="MSLAFTRFKETVNPNFCRNYLLDYQADSYADRKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQEAVTDDPEWNFMLNRQTYLQTLILVYLVERDERYL
                     LTAKGFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFDALTKQEERLIL
                     ASLEKQLHFLHANYLDKYSLSNWGILQTTAILLADAYFGSDLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDFTDTRDILTLAATILEEPHLKAAAFPTLDIDSLLLLGEKGVHTFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSICLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQINSSWAYLSYPKSNYCHLRQNGHVYF
                     IEGSYQTQFSDRNNYQHDRQILILPPGMFLIIDTIQAQGNHCLVSQFILDNHLEVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKFIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKRNPIETALSWHLKGKQFDYSICVLQEDLIKGEKLVLLNGHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            complement(13936..14757)
                     /locus_tag="VCX65_000368"
     CDS             complement(13936..14757)
                     /locus_tag="VCX65_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEP5052859.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYSNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFLPFITSLHLVMLENDRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPIFFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVILTVIIGVIGSWLGILA"
     gene            complement(14744..15526)
                     /locus_tag="VCX65_000369"
     CDS             complement(14744..15526)
                     /locus_tag="VCX65_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEP5052860.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGMILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVVIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWAFAFMGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            complement(15545..16033)
                     /locus_tag="VCX65_000370"
     CDS             complement(15545..16033)
                     /locus_tag="VCX65_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEP5052861.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQSIFIVVKDLQDAKRLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHHVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            complement(16069..17268)
                     /locus_tag="VCX65_000371"
     CDS             complement(16069..17268)
                     /locus_tag="VCX65_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEP5052862.1"
                     /translation="MTRSLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYGGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTPESREAALKAADKLIQRYQDKGGFIQ
                     AWGVLGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFMNRLPKDQVSYWDLIFGDGSEQSRDSSATAIAVCGIHEMLKTLPDHDPDKKTYE
                     AAMHSMLRALIKDYANKNLNPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            complement(17268..17705)
                     /locus_tag="VCX65_000372"
     CDS             complement(17268..17705)
                     /locus_tag="VCX65_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP5052863.1"
                     /translation="MIAIIVMGHGHFASGIVSSLELIAGPQEKVTAIDFTTEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGTTDDELGGI"
     gene            18040..18834
                     /locus_tag="VCX65_000373"
     CDS             18040..18834
                     /locus_tag="VCX65_000373"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEP5052864.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGVAAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            18859..19500
                     /locus_tag="VCX65_000374"
     CDS             18859..19500
                     /locus_tag="VCX65_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEP5052865.1"
                     /translation="MKIALINENSQAAKNGIIYDALTSVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEPSELVAYLKSVLEQ"
     gene            19529..20530
                     /locus_tag="VCX65_000375"
     CDS             19529..20530
                     /locus_tag="VCX65_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEP5052866.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEANIARTLG
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMSLTAWQGHRVGLYYLENGFGCRASQV
                     YYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDLIEILAREARKRQV
                     CVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADTTMI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLHNQRDVQR"
     gene            20535..21170
                     /locus_tag="VCX65_000376"
     CDS             20535..21170
                     /locus_tag="VCX65_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEP5052867.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHGYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGISFIRAIKSPLPQVEVMV
                     TGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            21466..22116
                     /locus_tag="VCX65_000377"
     CDS             21466..22116
                     /locus_tag="VCX65_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEP5052868.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLKKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSEKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            22812..23936
                     /gene="queG"
                     /locus_tag="VCX65_000378"
     CDS             22812..23936
                     /gene="queG"
                     /locus_tag="VCX65_000378"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEP5052869.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVMEDRIYPERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGLDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSN
                     GQFKEKFGMIAGGWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEMLAFMSHLTLKDEDSQKELELIRRKWQV"
     gene            24005..25103
                     /gene="prfB"
                     /locus_tag="VCX65_000379"
     CDS             join(24005..24076,24078..25103)
                     /gene="prfB"
                     /locus_tag="VCX65_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEP5052870.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            25122..25814
                     /gene="ftsE"
                     /locus_tag="VCX65_000380"
     CDS             25122..25814
                     /gene="ftsE"
                     /locus_tag="VCX65_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEP5052871.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            25807..26736
                     /locus_tag="VCX65_000381"
     CDS             25807..26736
                     /locus_tag="VCX65_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5052872.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(27046..27744)
                     /locus_tag="VCX65_000382"
     CDS             complement(27046..27744)
                     /locus_tag="VCX65_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEP5052873.1"
                     /translation="MPFIFRHSFFNKALIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPTPGHSWGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            27912..28676
                     /locus_tag="VCX65_000383"
     CDS             27912..28676
                     /locus_tag="VCX65_000383"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HEP5052874.1"
                     /translation="MSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQAAVD
                     KLSPEDTVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTTPLDTITEEQFE
                     KAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGCEGNPNLTVYGGTKFAVRGI
                     TQTLAKDLASEGITVNAYAPGIVKTPMMFDIAHEVGKNAGKDDEWGMEQFAKDITLKR
                     LSEPEDVANAVGFLVGDDSNYITGQTIVVDGGMVFH"
     gene            28784..31285
                     /locus_tag="VCX65_000384"
     CDS             28784..31285
                     /locus_tag="VCX65_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEP5052875.1"
                     /translation="MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLSHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLAYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFH
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFTR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRV
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETDCFLI"
     gene            31620..32813
                     /locus_tag="VCX65_000385"
     CDS             31620..32813
                     /locus_tag="VCX65_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEP5052876.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            32843..34189
                     /gene="asnS"
                     /locus_tag="VCX65_000386"
     CDS             32843..34189
                     /gene="asnS"
                     /locus_tag="VCX65_000386"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEP5052877.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            34604..35494
                     /gene="rapZ"
                     /locus_tag="VCX65_000387"
     CDS             34604..35494
                     /gene="rapZ"
                     /locus_tag="VCX65_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEP5052878.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYKVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            35491..36468
                     /locus_tag="VCX65_000388"
     CDS             35491..36468
                     /locus_tag="VCX65_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEP5052879.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNESDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYQGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            36465..37376
                     /gene="whiA"
                     /locus_tag="VCX65_000389"
     CDS             36465..37376
                     /gene="whiA"
                     /locus_tag="VCX65_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEP5052880.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSLIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYVQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
     gene            37509..38906
                     /locus_tag="VCX65_000390"
     CDS             37509..38906
                     /locus_tag="VCX65_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEP5052881.1"
                     /translation="MACTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMIVVKPEDQ
                     PRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATETITTNSR
                     VLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVAFSDEHDI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGIDYFEFNNPEDYLCSADLKDFIDTYHLDL
                     TYNHEHFNPRYAFGSQRDKDRHYNTPRAWIMQKFLNPEIVQDPRSFALAWCQKPYRKI
                     TVEDVKYVLSSHYQDTVYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRPNKPQEIA
                     AIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVSTDNFYWTNRLIAALADPHYNH
                     HETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQTLLNKIL
                     FDASNLMTNRFSLSD"
     gene            39058..40605
                     /locus_tag="VCX65_000391"
     CDS             39058..40605
                     /locus_tag="VCX65_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEP5052882.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGVIGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADVFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGVGHDHHHEEADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            40753..41475
                     /locus_tag="VCX65_000392"
     CDS             40753..41475
                     /locus_tag="VCX65_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP5052883.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRI
                     TIRLALKELELRDLIYKKQGKGTYVSGIKEPVTDLSSTYSFTEQMKKVGKTPKTEILS
                     FEQYQVTPYLSGLLEFDLDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKR
                     KALYDIFAKDYQETIRLAEEEFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILI
                     EFTFSIARADQFRYRVQHHPNG"
     gene            41495..42694
                     /locus_tag="VCX65_000393"
     CDS             41495..42694
                     /locus_tag="VCX65_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEP5052884.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDS
                     FLKRVCKSANGNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQCYLFESVASTDLVAAP
                     DYYLAEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKILALLQGGDINFSEDQFRL
                     DTRHLLPEAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(42791..43051)
                     /locus_tag="VCX65_000394"
     CDS             complement(42791..43051)
                     /locus_tag="VCX65_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEP5052885.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(43166..44107)
                     /locus_tag="VCX65_000395"
     CDS             complement(43166..44107)
                     /locus_tag="VCX65_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEP5052886.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLTWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LVSQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
     gene            44501..44950
                     /locus_tag="VCX65_000396"
     CDS             44501..44950
                     /locus_tag="VCX65_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEP5052887.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSDQFALTGAVKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            45125..45409
                     /locus_tag="VCX65_000397"
     CDS             45125..45409
                     /locus_tag="VCX65_000397"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEP5052888.1"
                     /translation="MRLEEIRQEINGIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QARENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRQYQTQRLTGGDIND"
     gene            45402..46664
                     /locus_tag="VCX65_000398"
     CDS             45402..46664
                     /locus_tag="VCX65_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEP5052889.1"
                     /translation="MIKSIATLPKPSLKEALGLIGLALPIGATVGVVDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFAYLLGWFKPYLSQKLPNPYFRIAFIGALLSICLMIGHV
                     GRYSGLGTHLIAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYTTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            46779..47126
                     /gene="rplS"
                     /locus_tag="VCX65_000399"
     CDS             46779..47126
                     /gene="rplS"
                     /locus_tag="VCX65_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEP5052890.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            47373..47444
                     /locus_tag="VCX65_000400"
     tRNA            47373..47444
                     /locus_tag="VCX65_000400"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47406..47408,aa:Arg,seq:cct)
     gene            complement(47487..47744)
                     /locus_tag="VCX65_000401"
                     /pseudo
     CDS             complement(47487..47744)
                     /locus_tag="VCX65_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770118.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            48140..48709
                     /locus_tag="VCX65_000402"
     CDS             48140..48709
                     /locus_tag="VCX65_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEP5052891.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVAMFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILEKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDINSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            48710..50662
                     /gene="gyrB"
                     /locus_tag="VCX65_000403"
     CDS             48710..50662
                     /gene="gyrB"
                     /locus_tag="VCX65_000403"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEP5052892.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEVIGTTDVTGTTVHFTPDPEIFTETTQFDYNVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRNFIEENAVYSTLDI"
     gene            51030..52754
                     /gene="ezrA"
                     /locus_tag="VCX65_000404"
     CDS             51030..52754
                     /gene="ezrA"
                     /locus_tag="VCX65_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEP5052893.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(52886..53344)
                     /locus_tag="VCX65_000405"
     CDS             complement(52886..53344)
                     /locus_tag="VCX65_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEP5052894.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQPPEKTKSFWKRFLKK"
     gene            53571..54878
                     /gene="eno"
                     /locus_tag="VCX65_000406"
     CDS             53571..54878
                     /gene="eno"
                     /locus_tag="VCX65_000406"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEP5052895.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV
                     DYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(55360..56388)
                     /locus_tag="VCX65_000407"
                     /pseudo
     CDS             complement(55360..56388)
                     /locus_tag="VCX65_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677767.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(56668..58209)
                     /locus_tag="VCX65_000408"
     CDS             complement(56668..58209)
                     /locus_tag="VCX65_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP5052896.1"
                     /translation="MLHLHLETKLQDKLSLLNILLDVSEVSIDQLCQETELKKQRVYN
                     LLFEMIKDLEDTLTLTICDDTVSIPYKTYQLKMPYFKKLYQTSIFLKMLCFLIEPGEL
                     SLHDFIKREYISQATAYRIRTNCRKYLKKVGLNVRQNHIVGPEYRIRFLIALLHYQFG
                     MTIYDFDKTSMNKVVSLIINSNQAITLNDASKAPYEFSYFAILISLIWKRRHDNLGIP
                     QTDAFKHLKKLSIYRDIKMTSQEIIGKWYHPDLTDEDLDYIFLCFCTTNNSFHKDKWT
                     PKKVKELFELVMTKTNGKTLKASLRPLLGNNILNSLPFKRILVSFSRLFISNLQVLLP
                     DIHLFHYLRRQQKRNKSFYNTLKTIVEEWMSAEGIVGKLPSYHLLLFTIQLEELLKTY
                     LPPIPVYLLTNNTAALDLMTNALSIYFPPAIATVMPVNVEIIPFKDIVKEKQSVIIAD
                     RQYLNLIQHLYQNQGHLFLYFLFSFRDVSEAYIHKAFLDFRQKRYDEFIVTLLDTYHK
                     NLSSP"
     gene            59565..64589
                     /locus_tag="VCX65_000409"
     CDS             59565..64589
                     /locus_tag="VCX65_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEP5052897.1"
                     /translation="MLKKIEVKEGQKNPISITLSEDQAKSLKNKEKLKVSIKQKQSKK
                     TSKDFFFEVGIDPKVKAKQQEKLLELDKVKKQIEDSINGDAWLPEKSEGEKPVQNTNK
                     ELQLQELNKKYQMAKEAIESATTLDDVETQFDKYTKVGDKDKYPDSLRNQYTRGDKDK
                     EIEKAKKSLGDLSDKVNGKIEEDKWLSDEVKKKQQQELEARKQKVNDSLKGSDSLKSL
                     RETVEKASSKNQKKPESFEDVYVPGNEETEKTKVRDILQKTYQKTEQNIETDPWLSPE
                     QKKAQKENAKARLDAGLKAVETTESLDKLKEVESDFLDKEKNPDSIPNQHKAGTPEVA
                     RKTFLDNFEKEAKKEIESIDKDDTLTANAKQVAKDKVAQQLQEATAKVEKAQSFDDLK
                     NIQDKFNSELPHTPGKPLKDQQSDAIAELEKKQQEIEKAIEGDKTLPRDEKEKQIADS
                     KERLKSDTQKVKDAKNADAIKKAFEEGKVDIPQAHIPGDLNKDKEKLLAELKQKADDT
                     EKAIDSDKTLTAKEKEEQKAKTKEELQKATEAVGAIDNREELDKKVPELKKAIEDTHV
                     KGNLEGIKNKAIEDLKKAHTETVAKINGDDTLDKATKEAQVKEADKALAAGKEAITKA
                     DDADKVSTAVTEHTPKIKAAHKTGDLKKAQVDANTALDKAAEKEREEINNDITLTAKD
                     KEQQLKEVETALTKAKDNVKAAKTADAINDARDKGVATIDAVHKAGQDLGARKSGQVA
                     KLEEAAKATKDKISADPTLTSKEKEEQSKAVNAELKKAIEAVNAADTADKVDDALGKG
                     VTDIKNQHKTGDPIEARRGLHNKSIDEVAQATKDAITADTTLTEAEKETQRGNVDKEA
                     TKAKEELAKAKDADALDKAYGDGVTSIKNQHKSGKGLDVRKDEHKKALEAVAKRVTAE
                     IEADPTLTPEVREQQKAEVQKELELATDKIAEAKDADEADKAYGDGVTAIENAHVIGK
                     GIEARKDLAKKDLAEAAAKTKALIIEDKTLTDDQRKEQLLGVDTEYAKGIENIDAAKD
                     AAGVDKAYSDGVRDILAQYKEGQNLNDRRNAAKEFLLKEADKVTKLINDDPTLTHDQK
                     VDQINKVEQAKLDAIKSVDDAQTADAINDALGKGIENINNQYQHGDGVDVRKATAKDD
                     LEKEAAKVKALIAKDPTLTQADKDKQTAAVDAAKNTAIAAVDKATTADGVNQELGKGI
                     TAINKAYRPGEAVKARKEAAKADLEKEAAKVKALIAKDPTLTQAAKDKQTAAVDAAKN
                     TAIVAVDKATTAEGINQELGKGITAINKAYRPGEGVKARKEAAKADLEKEAAKVKALI
                     TNDPTLTKADKAKQTEAVAKALKAAIAAVDKATTAEGINQELGKGITAINKAYRPGEG
                     VKARKEAAKADLEREAAKVREAIANDPTLTKADKAKQTEAVAKALKAAIAAVDKATTA
                     EGINQELGKGITAINKAYRPGEGVEAHKEAAKANLEKVAKETKALISGDRYLSETEKA
                     VQKQAVEQALAKALGQVEAAKTVEAVKLAENLGTVAIRSAYVAGLAKDTDQATAALNE
                     AKQAAIEALKQAAAETLAKITTDAKLTEAQKAEQSENVSLALKTAIATVRSAQSIASV
                     KEAIDKGITAIRAAYVPNKAVAKSSSANHLPKSGDANSIVLVGLGVMSLLLGMVLYSK
                     KKESKD"
     gene            complement(64775..64891)
                     /locus_tag="VCX65_000410"
                     /pseudo
     CDS             complement(64775..64891)
                     /locus_tag="VCX65_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611995.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        20354 a        11493 c        13801 g        19450 t
ORIGIN      
        1 aacataaaat acttgcattt tcattgtaat ttgctacaat agtaaggtaa agttagactg
       61 tatggcctac cgtctatcta taaaatatat tttattggag gcttttccta aaatggcaaa
      121 agaaaaatac gatcgtagta aaccccacgt taacattggt acaatcggac acgttgacca
      181 tggtaaaact actttaacag ctgcaatcac aactgtattg gcacgtcgct tgccttcatc
      241 agttaaccaa ccaaaagatt acgcttctat cgatgctgct ccagaagaac gcgaacgcgg
      301 aatcactatc aacactgcac acgttgagta cgaaactgca actcgtcact atgcgcacat
      361 cgacgctcca ggacacgcgg actacgttaa aaacatgatc actggtgccg ctcaaatgga
      421 cggagctatc cttgtagttg cttcaacaga tggaccaatg ccacaaacgc gtgagcacat
      481 ccttctttca cgtcaggttg gtgttaaaca ccttatcgtg ttcatgaaca aagttgacct
      541 tgttgatgac gaagagttgc tcgaattagt tgagatggaa attcgtgacc ttctttcaga
      601 atacgatttc ccaggtgatg accttccagt tatccaaggt tcagctctta aagctcttga
      661 aggcgacact aaatttgaag acatcatcat ggaattgatg gatactgttg attcatacat
      721 tccagaacca gaacgcgaca ctgacaaacc attgcttctt ccagtcgaag atgtattctc
      781 aatcacaggt cgtggtacag ttgcttcagg acgtatcgac cgtggtactg ttcgtgtcaa
      841 cgacgaaatc gaaatcgttg gtatcaaaga agaaactaaa aaagctgttg ttactggtgt
      901 tgaaatgttc cgtaaacaac ttgacgaagg tcttgcagga gacaacgtag gtatccttct
      961 tcgtggtgtt caacgtgacg aaatcgaacg tggtcaagtt attgctaaac caggttcaat
     1021 caacccacac actaaattca aaggtgaagt atatatcctt tctaaagacg aaggtggacg
     1081 tcacactcca ttcttcaaca actaccgtcc acaattctac ttccgtacaa ctgacgtaac
     1141 aggttcaatc gaacttccag caggtacaga aatggttatg cctggtgata acgtgacaat
     1201 caacgttgag ttgatccacc caatcgccgt agaacaaggt actactttct caatccgtga
     1261 aggtggacgt actgttggtt caggtatcgt ttcagaaatc gaagcttaat tttaattaag
     1321 ttcccagaat agcaatttaa gtcagacaac ttaagtttga agaagccccc aattcggggg
     1381 ctttttgcta tcttaaactc cataaaatgc tgataaataa gaatgaaaag ctttcagaaa
     1441 aagggttttt atttgtgaaa atattcctaa aatataagca attcctttta atcgtcggtc
     1501 atttgtgcta aaatagaaga tataaataaa aaaagaagag gtatgtgata tgtcacgtaa
     1561 accaattatt gctggtaact ggaaaatgaa caaaaaccct caagaagcaa aagcattcgt
     1621 tgaggctgta gcaagcaaat taccttcaac tgaccttgtt gatgttgccg tagcagcccc
     1681 agctgttgat ttggtaacca ctattgaagc tgctaaagat tcagttctta aagttgctgc
     1741 acaaaactgc tactttgaaa acacaggggc attcactggt gaaacatcac caaaagtgct
     1801 tgctgaaatg ggagctgact atgttgtgat tggtcactca gaacgccgtg attacttcca
     1861 tgaaacagat gaagacatta ataaaaaagc caaagcaatc tttgctaacg gtttaactcc
     1921 aattgtttgt tgtggtgagt ctcttgaaac ttatgaagct ggtaaagccg ttgagtttgt
     1981 aggtgcgcaa gtttcagcag cacttgcagg tctttcagca gagcaagtag cttcacttgt
     2041 tttagcttat gagccaatct gggctatcgg tactggtaaa tcagctactc aagatgatgc
     2101 tcaaaacatg tgtaaagctg ttcgtgacgt ggtagcagca gactttgggc aagaagttgc
     2161 tgataaagtt cgcgttcaat acggtggttc tgtaaaacct gaaaacgtta aagattacat
     2221 ggcttgtcca gatgttgacg gtgcccttgt aggtggtgca tcacttgaag ctgatagctt
     2281 ccttgctttg cttgatttcc ttaactaagt catctaaaaa agaaaaggtt aaatcctttt
     2341 cttttttaga tgacttaact cttactatga gagaataaag gtgattctac aggcaaatgc
     2401 attagcctaa tagcggttta atagcttttt tgccaatcta atgaaatgat atttgattgg
     2461 aaatggataa catctaaatg tccctggttt ttgcaaaata aagccattga aattctgttt
     2521 aaagcgcaag acaccgtctg aaccatcaaa ctttccagta ataccaagaa aattatattg
     2581 tttgatgccc ttgtgaattg ccttgagcat agcatgctct tgtaatagag ctgggctata
     2641 aaatttatta aatttggggt aagatcctga aaagaggtag acggcctctt gttcggtata
     2701 gataaaaaga cttcccgcaa ggaacacatc tttagttccg tactcttcaa gaaaatggag
     2761 agcttcagaa attcttacct gaaaggtttc gaattggctg gatagttctt ttaatctatt
     2821 ttgctttttt tcagaatgag gatttttgcc aaggtctcct ttaactttgt tgatgctggt
     2881 tgctagttgt agttgtcttt gtttaaggtt attaaggtaa tcttcaaaat taagagtcgc
     2941 aaccataaat tcacaagagt ctccaaaact atcataaaag tcctgatagt aagataatga
     3001 tttgtcaagg taatctctac gatcagaggt tgcttcagtg atttctttga aatggtgtaa
     3061 ctcatctcgt ttcagttgac gtaatttaat accaaaagta ttagcttttt ttattaaagc
     3121 ttttcctttt ttgctgaagg aatgggttaa acgtgaggaa tcaattcctt ctaacttttt
     3181 aacgtaatgc caaacaggtt caccctcagg atagcctgtt tttaaaccgt catgtttata
     3241 tcctaacgcc gttaaaaggc taataaggtc agtgtttgga tgagaaatag ggatgccatc
     3301 agtatcaaat gactgataat tgtcgtaagg ttttaaaatg agttcgataa cgtcattttg
     3361 tttggcatag tctttaagtt gagtgtaaaa atgttctaat tcttcgggat gattggtatt
     3421 agggcctgca ttgagttcca tacgccaacc tccagccact ttttggctaa agaccatagc
     3481 agcaaccttt agttcaccat ctttttcaag tccaagaaat tgtggttttg cccctctttt
     3541 agccatcaag ctggccattt ctgaggtttg gataaaggaa tgatggacga gactgtggca
     3601 gtaatggtca aattgttctt gtgaaatttc aattagtgcc attagttgtg ctccttaatt
     3661 tttttcttaa gttataggtc aagatggcta agcttgaaac aaggccgaca ggaatgttga
     3721 attcacctgc aaattcttcg atggtggggt tgagtctagc tttgaaatga tagagtccac
     3781 catcttgttg attttccaca cctcctaaat tatgccagcg gcagcctctt ttaaaagctt
     3841 ctttagccgt ttcataccag gttaaaagag gagcttgata attgcgataa tcatcgtcca
     3901 ttcccgcata aagattttca gaagtctcgc cataaatcaa ggttagggtg gcggctagtg
     3961 ggatgcgggt tttgcctgca gcgagctgct cgcttaaaat ggttaaatct ttttgtagcc
     4021 gtgcaatggt tttttgattt tctgctactt tgctaggttt actcttatct gttaatcgtg
     4081 cttgttctgc taaggccttg tccaactgtt ggatcaagag ttttttttgt tcaggtaagt
     4141 ctaaactagc catagtaatg taggactgac cagcataaat atctagtaat ttttgatagt
     4201 aggatttgcc tcgaaggata atgccttttc gattctcggt ttttttcatc aaggctgaaa
     4261 agtcgtctag caattcactg ccaccaatcg tgacattaac acctttattg gtagcggtac
     4321 gaatggattg cttggctttt ttgggcaggc tgtcaaagtc aaaatccttg gcgtagatgt
     4381 tggcttgtat tcttggttga atagtgtctt cgagttcttt tgttctgcca gaccattcga
     4441 taccaagttt ttttagaaaa gcaataatag agagtgtcac atcattttct ttgctttctt
     4501 ttccttctaa agtttgtttg atgactaaac ttggatcaat tttgacaaaa agcgctcgtt
     4561 tgctttttcc gaaagttttg agcgttttaa tgacgaaatc aaggagttca aaattggcgt
     4621 agtccatgat tggcccacgt gggatataaa tcatagtgaa accaagagga agttttctga
     4681 ttaaacaagc agcagcagca acttgtaccc cattttcata aaagctgatg cgttcgtgtt
     4741 tccaattatc tttgactttt ctccactttg aactttgaag taagccagct tgtggctgtg
     4801 ctaagacaaa ctgatcatgt tcttcaggag atattccgat tttatatgta tacattagtt
     4861 taatacccac ttgcgaatag catgtgccac accactgtca ttgttggatt tggtgatgta
     4921 tttggctatt tttttcaatt caggaacccc attttccatg acaacagggt tggcaacgac
     4981 ttctaacata gcacgatcat tttcagcatc cccgatggcc atggtttgtg acatatctag
     5041 cccgagtttt ttagctaagt gtttgatggc attgcccttg ctgacggttt ttggcatgaa
     5101 ctctaaataa aaaggggttg acttgacgat ggtgtactta tcaaagaaat gttgaggaat
     5161 ttgcttgatg gccgcgtcca aaaggtcagg ttcatcaatc atcatcattt tgatgatttc
     5221 tttattggtc atttcttcgg gagtgcgata gaaaataggc atgtttacca aagtcgattc
     5281 atgaactgtg tattttccaa tattccgatt ggcagtgtaa ataccttctt tggtaatggc
     5341 atgcatgtga actcctaatt ttcggctcaa aaattccgtt tccagataat cgtcgtaagt
     5401 catcaattct ttaacaattt cttcgccggt ctcggcatct tgcaccaagc caccattaaa
     5461 agtgataacg tggtttcctt tgtggttgag ttctaattgt tcgagtaatg aaatcactcc
     5521 ggcaataggt ctgccagtag caatcaccat atgaacccct tgggctttag cctcttggac
     5581 agcttgaaaa acatcatctg taattcgacg gtcatcagtg agtaatgtgc catcaatatc
     5641 gacagcaacc agtttgatag acatggcatc ctccttgttt ttttgtggtt tatcttaaaa
     5701 atgttctccc tcctatctta ctaaaaatag gtgcttttgt catgggatga gaaaggaaac
     5761 ttaaggaaaa acgagagaaa acgttttagt ttagctcaat cgcctctgta gtaactaaaa
     5821 agattgaaga aagtactctt tcttcaatct tagaatggag acaaacccag tttgatgctc
     5881 aaaaagcatg aactgctctg ctgatttgac aactgatttc ttatttctgc gtgtgacgtg
     5941 agccaaaaca gctgcttttt gctgtggcaa aagtggtgtc aatactggca gtgacgttac
     6001 gcggaatttt tgagacccta ggctcaaaaa taaagcatag aattccaaag gaagtcgctg
     6061 ccataagcat cacctaagaa aagtatcaaa aaagactttt tctgcaatct taaagggctt
     6121 tactgactaa agtgaaaatg cccattggaa atataactca taaaagtttc cttgctagga
     6181 gcaaagaggt catcgagctc taacatttcc tttggaaaat aaaagcgacg gtctccgtag
     6241 gttgtccctg ttaatgcttt gacaatagga gataactgag ataattcagc aaggctcccg
     6301 tctttttgta tcatttcaat ctgagttctt ggattttcga gctctggtcg ataaatatca
     6361 taaggcaggt cgaagttgat atggataccg gtgtaataat ctggatcaaa gccaactgat
     6421 tcgaccaatt ggcgcaagcg ttctaactct cctcgggaat cttggtcaaa ggtaacagac
     6481 ttcagaattt ttcgattaat aaagcgactg gccaaatctg ataagatatg gtcttcgctt
     6541 gccatccaga cttggaagta agtattcatg actccgtcat ctagggctat ataatctgct
     6601 aaattagcct tcttttcaaa gaaggggatg agtccaggag ctgttttttg gaaataagcc
     6661 tgttgctcag gatataagtg ttgggctctt ttgaggagat tttgtaagat gagctcaaca
     6721 gcacggctgg cgggatgaaa atagacctgc atgtacattt gaaaacgact gacaatatag
     6781 tcctcgacag catgcatacc actatgttca aagacaatgc catcttcaac aggtcgaatc
     6841 acacgtagaa tgcgcattaa atcaaactga ccataattgg cagcagaaaa ataagaatct
     6901 cttaaaaggt aatccatacg gtcgcagtca atctggctgg aaatcagttg cacaacttgc
     6961 ttgttaggat aggtatgatt aatcacgctg gcaactttgt ctggaaaatc aagagcatga
     7021 cgcaccaaaa tggcattgat ttctgtctca ggattggtaa ttatctcctg agtaaaggcc
     7081 tcgtgatccg tatgaaaaag aacctcaaag gtatgagaat aggctccatg accaatgtca
     7141 tgtaagaggg cagccgtcat agtgaccaga ctttcatctt tattccagat atcagcgtat
     7201 ttctcttcaa aaatagctgt cacccgacgg gcaatttcgt aaacacctag gcagtgagaa
     7261 aaacggctat gttctgcgcc gtggaaggtg aaagctgttg tagggacttg tttgatgcgt
     7321 cgtaagcgtt ggaattcttt ggtattgata aggtcataaa ttaatggatt atcaatgtgg
     7381 atatagttgt gaacagggtc acgaaatact ttttcattca taatttttat tatatcaaaa
     7441 attgataaaa tagggagaaa ttgatagaat aaacagacga gcttagaata gaaagaagag
     7501 ttatgaaatt acagttaacc aaccatattc gctttggaga tgagacagag attattcaag
     7561 aaattcatga ttgtgagtgg cgagaaaaag ggggctatca gtacctcatc tatcaaaaca
     7621 ctgacaagga aaaggttgtc atcaagtata atgagacaga actgaccatg agccgttttt
     7681 ccaaccctca gtcaatcatg aaattttttg cgggcaagaa ggtcctgatt gctctaccta
     7741 caccgatggg ggttcaacaa tttttgacag ataccagtca ttaccactta gattgttctt
     7801 gtcaaaaatt ggaccttcat tatcatttgc ttcaagctca aacagaaatg ctatttgcaa
     7861 gctatcatct tgagctgagt tgggattaac taaaaagata gcagtaaatc atctgattag
     7921 ggattattct tgttttttag tcaggttttt actataatgg ttattatatc aagggagtag
     7981 cagacggcta gccgtgattg tatcgtcaat acggaatttc ggtttccggt acaatcttaa
     8041 acagcgagac ttgtttaaga aaataaacag gtctttttat ttgaacaact aaaataaaaa
     8101 gaccaaggag gtactaattt gtctaaagaa caaagacatg aagcatttta cacgcaaagt
     8161 gaagagaccg tactggctca attagagacc agtcgcgaag gtcttacgtc tgcccaagca
     8221 aaagagcgct tagcagagta tggtcgtaat gagcttgatg aaggcgaaaa acgaagttta
     8281 tttatgaaat tccttgatca atttaaggat ttgatgatta ttattttgat tgtggcagcc
     8341 cttctttcag ttcttacaga ggggatggaa ggtttgacag acgccattat tatcttggct
     8401 gttgttatcc taaatgctgc ttttggtgtt taccaagaag gacaagctga agctgctatt
     8461 gaagccttga aatcaatgtc aagtccactg gctcgtattc gccgtgatgg gcatgtgact
     8521 gagatagact ctaaagaatt ggtccctgga gatattgtct tgctagaagc gggagatgtt
     8581 gtccctgctg atctgcgtct tttggaagct aactccttaa aaatcgaaga agcagcgctt
     8641 actggagaat ctgtaccggt tgaaaaagac ttgtcaacgg ctgtttcaga agatgccggt
     8701 attggtgatc gcgtcaatat gggatatcaa aactcaaatg tgacatatgg tcgtgggatt
     8761 ggggttatca ctaacactgg catgtacacc gaggttgggc atattgctgg tatgcttgct
     8821 aatgctgatg agacagatac accattgaag caaaaccttg acaacctttc taagattttg
     8881 acttatgcga tccttgtgat tgcagcggtg acttttgctg ttggagtctt cttgcgtggt
     8941 caacacccgc ttgaaggctt gatgacttca gtagcgcttg ccgttgcagc tattccagag
     9001 ggacttcctg cgattgttac tgttgtgctt tctcttggaa ctcaagtact tgctaaacgt
     9061 aacgccatta tccgtaaatt accagctgtt gaaacgctag gatcaactga aatcattgct
     9121 tctgataaaa cgggtacctt gacaatgaat caaatgaccg ttgaaaaagt ttataccaac
     9181 gggacactcc aaagttcatc agctgatatt gcttttgaca atacgacact tcgtgtaatg
     9241 aactttgcta atgatactaa agttgatcct tcagggaagt taattggtga cccaacagaa
     9301 acagctttgg tacagtttgg gttagaccac aattttgacg tacgtgaggc tatggtggca
     9361 gaacctcgtg tggcagaatt accatttgat tctgaccgta agttgatgtc aaccattcat
     9421 aaacaagctg atggcaaata tttcatcgct gttaaaggtg cgccagacca attgttgaag
     9481 cgtgtcacac agattgaaga aaatggacaa attcgtccta ttacggatgc tgataaaaaa
     9541 accattcttg ataccaataa gagtcttgcc aaacaagctc ttcgtgtctt gatgatggct
     9601 tacaaatatt ctgatgctct tccaacactg gaaacagaaa ttgttgaggc taatcttgtc
     9661 ttctctggtt tggtagggat gattgaccct gaacgtcctg aagcagcaca ggctgttaaa
     9721 gtagctaagg aagctggcat tcgtccaatc atgattactg gtgaccacca agatacagca
     9781 aaagctattg cgaaacgtct tggtattatc gaagaagatg gcgttgatca tgtctttaca
     9841 ggtgctgaac tcaacgaatt atcagatgaa gagttccaaa aagtctttaa acaatactcc
     9901 gtgtatgccc gtgtatctcc tgagcataaa gttcgtatcg ttaaggcttg gcaaaatgaa
     9961 ggcaaagttg ttgccatgac tggcgatggg gttaacgatg caccatctct taaaacggca
    10021 gatattggta ttggtatggg aattacaggt acagaggttt ctaagggagc ttctgacatg
    10081 gttcttgccg atgataactt tgcaaccatt atcgttgcgg ttgaagaagg acgtaaggtc
    10141 ttctcaaata ttcaaaaaac aattcaatat ttactttctg ctaacatggc agaagtcttt
    10201 accatcttcc ttgcaacctt gtttggttgg gatgtgcttc aaccagttca cttgctttgg
    10261 attaacttgg taactgatac cctaccagct attgctcttg gtgttgaacc tgctgagcct
    10321 ggtgtgatga aacacaaacc tcgtggacgt aagtcaagct tctttgatgg tggggtgaag
    10381 gaagccattc tttaccaagg tgccttccaa accattttgg tgcttggggt ttatggtttt
    10441 gccttgatgt tcccagaaca cacaagctac catgatgtcc atgcagatgc cttgaccatg
    10501 gcttatgtga ccctcggttt aattcagttg gtacatgcct acaacgtgaa atctgtttac
    10561 caatccatct ttactgttgg gttgttcaaa aacaaattgt tcaactattc tattccagtg
    10621 gcctttgtag cattgatggc aacagttgtt gttcctggat ttaatcaatt cttccatgtg
    10681 acacacttga cgatcacaca atggttagtg gttattatcg gaagtctctt gatggttgtt
    10741 cttgttgaat tggtgaaagc tgttcaacga tcacttggtc aagatgaaaa agcaatttaa
    10801 tagacgctaa aaggtttgag acaattgtct caaacctttt tttataatcg ttacaacgat
    10861 aaggactatt ggtatgcctg acattaaaaa gttgattctt gccaattgac ttgacagtca
    10921 aaaatttgtt gtttggcttc ttgactgtga ccttcaatat catcgattaa aatcttagta
    10981 gcctgttcgc cttcttcata ggcgggttgg ataatagttg ttagtgttgg tgaagaaaat
    11041 tttgtccact caatgttatc aaatcctact agtccaatct ctggtatatt aaatttaaga
    11101 gacttcatag ctgtaaatac ttttggaaga gcccaacaat tggggacaaa aaccaaactc
    11161 tttttagtca gtgatccttg caaaaactga gcgattgcct ctgaagaagt ctgattttca
    11221 tcaataatca tttcttgatg agtaagatga ttagcttcta acacatcaat gaagcctgaa
    11281 gcgcgttcaa tacgagtgct aagtaaattg gggttacccg tgatcatgat aaaatgttca
    11341 taacctttat cgatacattg ttgaatggta tcataaacag catcataatt attagttttg
    11401 acccagtttg tgcgatgttc gtaaagttgg ctatcaaaaa agaccacttt tttcttctta
    11461 atatcgataa tgcgagaata cttcctgaaa ttagaggtag gctgaatgat aaagccatcc
    11521 actccgaggt tcagcatctt ttcaatgagt tcatcttcgc gagaagggtc gtagttgctg
    11581 tttccgatga taatttggta accaaattcc tgggctttgc tttcaattcc cttaacaatt
    11641 tgattggaaa aactattggt aatatcacca ataaccacgc caatgagttt agtagatttg
    11701 gcgtttagac ttctggcagc aatgcttggt ttataattgg tagcttcaat cgtgctttta
    11761 atgcggtttt tagtttcttc agacatcttg tcaaacctac catttaagta gaaagaaact
    11821 gttgtttttg aagttttcgc taattcagca atatctttga tggttacttt gcgctgcatt
    11881 gcatacactc ctttaaaata gtaatggtta gtcatattat aacataagga ctcgtaaaag
    11941 atttagtgtt tcaatcgaat aatctcattc gtgatatggt tgataacaac cacctttcct
    12001 ctgattttat gaccatttag gagaactagt ttttctcctt taattaagtc ctcttggaga
    12061 acgcagatac tgtagtcaaa ctgctttcct tttaaatgcc aggaaagggc ggtctcaatt
    12121 gggttgcgtt tgcctgtttg aagtggtgtt aagggagtaa ctttggtatc gtcagggact
    12181 aacagggtac tggtgcaacc cttgtcttta aagggttttc gtttgatgaa tttgtgacta
    12241 gtcaggtatt ggttgtattt ttttgacaaa atcgtttctt cgatagtgaa agggcagtca
    12301 ctgattagtc tgaggtcact aaggtgatct gtctttactt ctaagtgatt atcaagaata
    12361 aattgactga caagacagtg gttaccttga gcctgtatcg tatcaatgat aagaaacatt
    12421 cctggtggta agatgagaat ttgtcggtca tgttggtagt tgttcctatc agagaattgc
    12481 gtctggtagc taccttcaat aaagtaaacg tgtccatttt gtcgaaggtg acaataattg
    12541 gatttggggt aagaaaggta agcccaggag ctattaatct gctcaggtaa ttgttcttct
    12601 aagaaggcgg tagaatgatg gctagcgctt tttagggcat agcgtaatgg ttcttctttg
    12661 taagtgtatc gcccagcatc acagaaaagt ggttgtcctt tataatagag acagatacta
    12721 ttttggtcgc tatgggtatg ggaactaccg atgggcccat ttttgaaaaa aagataataa
    12781 ttttcttgat tgatggtaat gtgcccggaa tgttcaaagt gatgcgcaaa agttggtaag
    12841 gtttggacgg gtaactgttc aaaagtgtgg acaccttttt ctcctagaag gagaagacta
    12901 tcgatatcaa gtgtgggaaa agcagcagct tttaagtgtg gttcttcaag gatagtggct
    12961 gctagtgtta gaatatctct ggtatcggta aagtcactgt ctcctaaggg gatctgtttg
    13021 tggtcagggc cagtcatttt gaggagataa tcactcatgg caagcaaagt aggtctaagc
    13081 tgtggaagat aatcagggac tagagcagtt aattccagaa gggctttgag tacttccaca
    13141 tgatacatgg ttgattgttc aaattgactg ccgtcttcga gaatttggag tgcgatttgt
    13201 tgcgtcaatt cttttctagc gaaagctgtt gctgcagcaa tatcaaggtc agaaccaaag
    13261 taggcatcag ctaataaaat cgcagtggtt tgcaagattc cccaattgct gagactgtat
    13321 ttatcaaggt agttggcatg gagaaagtga agttgttttt ccagggaagc taggatgagc
    13381 ctttcctctt gcttggttaa ggcgtcaaaa agattaaggt aaatcaaaca tttgacccaa
    13441 gcaaaacaac ggatgccagt atctaaggtt ctagtagcta accccttagg atctaaagga
    13501 atagctgatt caatccaatt gagaatgaaa cctttagctg ttaagagata ccgttcatct
    13561 ctttcaacaa ggtagacgag gattaatgtt tggagatagg tctgtcgatt taacataaaa
    13621 ttccactcag gatcatctgt gacagcctct tgccaagtaa tgggatctaa gtggtaaggg
    13681 atgtggcagg gctccatatc ccaattatct tcaaataaaa aggtattggt taagagtagg
    13741 tcagctatcc tttttcgatc agcatagctg tcagcctgat agtctagcag gtaattcctg
    13801 caaaagtttg gattgactgt ttctttaaag cgtgtgaagg caagagacat aggacgtttc
    13861 ctttccaaaa gaaaagagac ctgttaatgt gactaggaaa tagttcctaa acccataaca
    13921 gaatctcagt gacaactaag ctaaaatacc caaccaactg ccaataacac caatgataac
    13981 agttaaaatg accaatttgt aggttgtcca ttttttgttt ttaataaggt aatacatgag
    14041 taaggtaaag agagctggta aaagtgcagg ggcaatctta tcaagcattc cttgaatagt
    14101 cacaaatttt tgtgctgtat tggccgcatc caccttgcca gccgcaaaag taatgggaac
    14161 agttatttta acagaagtag cagctaatcc agcgataacg gtaacaccga caatatttgc
    14221 catacgagat actatcgcca tttgttcgct tagtttatca ataaagcttg tgccgacctt
    14281 gtagccatag agaccagaac cgattttaat agcagttagg ataatattca tggctaggaa
    14341 gaagaaaatt ggacctaaca ctaaaccatc actagctaag gaagctgcaa tcgttgaaaa
    14401 gagtggcgcc aagcaaaatt gtgataagga gtcaccgata ccagctaaag gccccataag
    14461 tgccattttg atgtttcggg tttcttcttc aggacgatca ttttctaaca tgaccaagtg
    14521 cagactggtg atgaaaggaa ggaagtgagg gttagtattg taaaactcac agttatcttc
    14581 taaagcttga tataagccct ttttatcact gccaaaatgt tttttcaagg caggatagat
    14641 gacattggcg tatccgatac cttggtaatt actgtaatta aacccatttt gtaggaagaa
    14701 agctctcaga gctgttttga ggtaatcttt cttggttaat ttattagatc cagtcatctt
    14761 gttggcctcc ttggacagtt gttgcatcga cttgtttagg tttgttgtaa aattcattca
    14821 aggcgaaaat gataccaata atggcgatac caatggttgg aatttggagg taggctgcac
    14881 aaacataacc aatcagtaca aaaggaatca actccttctt ggccataact gataagatca
    14941 tggcaaatcc gatagcaggt aacattttac cagcaacagt caatccattg agcaagacag
    15001 gtgggatata atcaaccaag tgaaggaggg tatccattga caaggcacct aataaaccaa
    15061 ggcctaatcc cataaaagcg aaagcccaga tagtgccgtt ggcagcgaat ttgaagcctc
    15121 taatattgcc tttttgcaat tgttttttag cggtttcagg agccccagca aaagcggtat
    15181 aggcgaatgt ctgaagaaat tggatgacaa ctgcgattgg tgttgataag gctagggccg
    15241 cttctggggt aactttacca gcactggtaa tagccatcaa ggtaccaaag ataccagggc
    15301 cgataggatt aggaggaacg gtaccaccgg cacccactcc aaatcccata taagctaatt
    15361 cggagatagc tcccatgcta agtgcagttg gcaagtcacc taagatcatc cctacaccaa
    15421 aagacagaat aatacaacgg ttggtgtaga tgccaagtaa cattccgctg aaacaaaagg
    15481 ctgtccaaag accaattaaa agtgcctgta acaaattgat atccatatca atctccttta
    15541 ttcattaaat ataatctaag atgtcaacgt cagaggcgct attgccagct ggagttgttt
    15601 tggtgttaaa aaccacgtgg tggtcatggg ctaagcaacg aatagcagac ttgtctgttt
    15661 ctcccagcga aataaactgg gtaatcgcaa ccttatcatc agttttatga atattaccga
    15721 tattgatttc tgtgatggga acaccccctt caactaggcg tttggcatct tgcaaatctt
    15781 tgaccacgat gaagatactt tgagcaggac ttgctttatg aatgatgtca atcacttttt
    15841 gaatggagaa aaaacgaatg gcaatactgg atggaataac tgttttcatg agggattgtt
    15901 gaatcttatc ttcagaaacc gcatcgttag cgacgataac ggtgttgcag ttgaggaatt
    15961 tgacccataa ttgcccctgt ccgtgaatca agcgctcatc aactcgcgtc atgataatgt
    16021 ttggttgtgt cataaaatct cctttttaaa tgtcggtatc ggtgtttgtt accagtaagg
    16081 gttccagtct ttgtagaaac gaagcagagc ttcaagatag taatagtctc cccagatatt
    16141 tccctcgtca accccttttc cagagtgcca agaatagact ccgtgaagta gtagaggagc
    16201 gccaggattg agatttttgt tagcataatc cttaatcaag gctcttagca tgctgtgcat
    16261 ggcagcttca tatgtttttt tatcaggatc atgatctggt aaggttttta acatttcatg
    16321 aataccacat acagcaatgg cggttgctga actatcacga gactgctcgc taccatctcc
    16381 aaaaattaaa tcccagtagg aaacctggtc tttaggaaga cggttcatga aataatgggt
    16441 catgcccttg aagagttgaa tgagttcagg ttcttttagg aaacgatagg tcaaaggaat
    16501 accataaatg ccccaagctt gccctctggc ccaagcagaa tcatcgctat aaccttgtcg
    16561 ggtgacccct ttaataggat cgcctgtttc tggatcaaag tagaaggtgt ggtaagcaga
    16621 ggcgtcatct cggatgacat gattggctga ggcgtagaaa tgattgatcg ccatgtcacg
    16681 gtaacggttg tctccagttt cttggctagc aaaaaagagt aattggatgt ttaggagaca
    16741 atcaatgatt aaacggtaat cttctttttt acccagcacc ccccaggcct gaataaagcc
    16801 gcctttgtct tgatagcgtt ggattaattt gtcggctgct ttcaaagcag cttctctaga
    16861 ctcaggtgtt tttaaaagtt tccactcagc catgcaagaa ggggtgtaaa gaaagcccaa
    16921 atcatggtga tctagctcaa tatctcttgt tactcgatct aggaaagaaa ggtcatttgc
    16981 ttgagccaga gctttaatgg catcatcccc accgtattcg taagctaacc aaaggcaacc
    17041 tgtccaaaag gcattggtcc attccgtgtt gtccataatg gcgtattggt tatctttggt
    17101 agctggcgtt ggaaagtctt ctttaaaata gtccatatta agccgaactt gtttgagggc
    17161 taagtcaagg gcctgagtaa tgtcttcttg gcttagaaag tcttctttgg taaatcgttc
    17221 aggctgcttg ataggttcaa gagcaatggt ttttaaagat cgtgtcatta aatgcctcct
    17281 aactcatcgt ctgtcgtacc gtcttcttgc tgagaaagag ttttccagtc aacaatgcct
    17341 tctttagaac atgttataag tcctgatact aagtcgtcaa aagaagctgc tgtttgtctt
    17401 gcaaaactag cttcaatcag catggctaag ttaaggccag aaagaacatt acacgtcgtg
    17461 tttggaagag attccattaa ggttgcagcg actttaaaag gggtacctcc tagaaggtca
    17521 caaagaacta aggtttcctc ttctgggatt aaagcacgag ataattggtc ctgcacatca
    17581 gcggcggtca tctcagtagt aaaatcaatt gcagttacct tctcttgtgg tccggcaatt
    17641 aactctaggg atgagacaat cccactcgca aaatgtccat gtcccataac gataatagca
    17701 atcataaata aatctccttt ggtttaccgg tttactcaaa aatattgtag cgctttcaaa
    17761 attctttgtc aatacttttt ttaaaagatt tttgaaaaag aaaaagtgaa cggttgtgct
    17821 aaaaaagaat caaaaatggt cttttttgtc actatttaat gtagaaaaat cttaatagct
    17881 attaagtata ggacaagact aaacaagaat gacagtttgg ataagagcac tcttttaaat
    17941 tttgaaccgt tttcattaaa atgattgaca aaactagttt actttgttat agtcttggta
    18001 aacaggttta cttaatctaa taacaaaaag gagaatccta tggaaaatat gttttcgtta
    18061 caaggtaaga ttgccttgat taccggagca tcttacggta ttggttttga aattgccaaa
    18121 gcctatgctc aagcgggtgc aactattgtg tttaatgaca tcaaacaaga gttagttgat
    18181 aagggggtgg ctgcctatcg agagttaggg atagaagcgc atggctatgt ttgtgacgtg
    18241 actgatgaag ctggtatcca acagatggtt agtcaaattg aagatgaagt aggtgttatt
    18301 gatattctgg tcaacaatgc aggtattatt aggcgtacgc cgatgcttga aatggccgca
    18361 gaagattttc gtcaagttat tgatattgat ttaaatgctc cttttattgt gtcaaaagct
    18421 gtattaccat caatgattgc aaagggacat ggtaaaatta taaatatctg ttctatgatg
    18481 agcgaattgg ggcgtgaaac agttagtgcc tacgcggcgg ctaaaggtgg cttgaaaatg
    18541 ttaaccaaaa atatagcctc tgagtttgga gaagccaaca ttcaatgtaa tgggattggt
    18601 cctggctaca ttgcgacgcc ccaaacagct ccgttgagag agcgacaagc agatggtagt
    18661 cgtcatcctt ttgatcaatt tatcattgct aaaacaccag cagcacgttg ggggacaaca
    18721 gaagacttag ctggtccagc tgtttttcta gctagcgatg ccagtaattt tgtcaacggc
    18781 catattcttt atgtcgacgg tggcatttta gcttatattg gaaaacaacc ttaatcacac
    18841 actagaaaga gattttatat gaaaattgca ttaattaatg aaaatagcca agcggctaaa
    18901 aatggtatta tttacgatgc ccttacctca gtgacagata aacacggcta ccaagtcttt
    18961 aactatggca tgtatggcac agaaggtgaa agccagttga cctatgttca aaatggactc
    19021 ttagcttcta ttttattgac cactaaggcg gccgattttg tggtgactgg ttgtgggaca
    19081 ggtgtgggag ctatgttggc cttgaacagc ttcccagggg ttacctgtgg ttttgcgagt
    19141 gagccaacag aagcatatct cttttctcaa atcaatggtg gtaatgcctt gtccattcct
    19201 tttgccaaag gttttggttg gggagcagag ttgaatttga ccttaatatt tgaacgcctc
    19261 tttgcagaac caatgggtgg cggttaccct aaagagcgag ctattcctga acagcggaat
    19321 gcacgtattt taagtgatct gaaaaaaatt acttacagag atttgttggc aattgtcaaa
    19381 gacatcgacc aagatttcct caaagaaacg atttctggcg ctcattttaa agagtacttc
    19441 tttgccaatg cggagccgtc agaattagtc gcttatttga aatcagtact tgaacagtaa
    19501 ttccattttg acgaggaaag gaggtcacat gtctaagtta ttattggttg gtgaaccgct
    19561 gattcgcgtt agccccaatc agtttcagcc tttgaccaat gcctgcgacg ctcagctttt
    19621 tttcggcggt tcagaagcta atattgcaag aactctaggc ggttttggct tagaagcaag
    19681 gctatttacg gccctaccag ataatcctgt tggtcacgct tttcatcagt ttttgaagca
    19741 aagcggtgtg gacatgtcct tgacggcttg gcaaggtcat cgcgttgggc tatattacct
    19801 tgaaaatggc tttggctgtc gggctagtca ggtttattat gaccgctgtg gctctagctt
    19861 ttcggcctta gataaggata gtcttgattt agctgccatt tttgaaggca ttagtcactt
    19921 tcattttagt gggatcagtt tggcgctggg caaaaaaact caggatctga ttgagatact
    19981 agcgagagaa gctaggaaaa ggcaagtttg tgtttctttt gatcttaact ttagatctag
    20041 tatgattgcg gtagctgatg ctaaacgact cttttctcac tttgctcaat acgcggatat
    20101 tatttttggc atggaacctt tgctgttaga tagtgacgat tttgacatgt ttgataggaa
    20161 taaggcagat actacgatga ttagagaacg tctggcagga ctttatcagc gctatcagtt
    20221 acaagctatt taccatacgg agcgttcaaa tgatgcccaa ggcagtaatc gtttcaaggc
    20281 ttatgcctat gatgggcagt tttacgaatc ctgtgaagtg acgaccccag tcttgcaacg
    20341 ggttggaagt ggagatgctt ttgtggcggg tttactttat cagttgttag aaggtaacga
    20401 aaagcagcgc aaccttgatt ttgctgtggc aacagctagc ctaaaatgta cagtagctga
    20461 agatcagctc tatcacagcg tccaacaagt agaagcagtc ttacataatc aacgggatgt
    20521 ccagaggtga tgatatggga aaaatagaaa tcttaaccaa acttaaggct aatcggcttg
    20581 tcctggttgt acgaggagag tctagtgagg aagctttagc ttgcagcctg gccagtattg
    20641 aaggtggcat taagacaatt gaagtcacct atactaaccc ctttgctagt gaggttatcg
    20701 gtcaattagc tgaacgcttc aaagaagatc ctgaggtatt gataggtgct gggacagttt
    20761 tggatgatgt cactgcccgc caagctattt tagcaggagc acagtttatt gttggtccta
    20821 atttcaatcg agcagtggct ttgatttgtc atggttatag cataccttat ttaccaggtt
    20881 gtatgacggt taatgaagtg gttacagcat tagaatcagg ggttgatatg gtcaaaattt
    20941 ttcctggttc tactgtaggg atatccttta ttcgggcaat caaatctcct ttgccacaag
    21001 tagaggttat ggttacaggc ggagtttctt cagataatct caaagactgg ctagctgctg
    21061 gagtagatgt tctaggcata ggaggcgagt ttaatcagtt agcgagccaa aaacaatata
    21121 acctaatcac taagaaagcc gctcattata tcaaaagttt gcgacaataa tctaaaaaac
    21181 gtttttacct tggctttagt gctagtaaaa acgttttttt atcattcatt caattaatat
    21241 gcttctgctc atgtttttcc agatagtata gatataagag cagctaattt aacaagatga
    21301 gcctgttgtt tgatatatag gatataaact ttttatgatc aaacaaaagt aatacctttt
    21361 gaattcgtta gtattgatct gatctaaagt gacatcactt agaatggact agctgtacag
    21421 cttttacagc aacttatgct aaaatagaaa aaaggagaaa tgttgatgat taaaggaatt
    21481 atttttgata tggacggtgt tttatttgat acagaacctt tttatctgag gcgacgagaa
    21541 gattttttta agacaaaggg aattcccatt gatcatttga actctaaaga ttttattggg
    21601 ggcaatcttc aagaattatg gaaagagttg ttaggtaaaa atagggatga tgctatcgtt
    21661 aaggcaatta caactgacta tgacgcttac aaacaagcgc ataagcctcc ttatcaaaaa
    21721 ctgttgatta cagaagtgaa ctcttgtctt gaacagttga aaaaacaagg tattaaactg
    21781 gctgtggcat caaactcgaa gcgtcaggat gttttgttgg cgttggagac aacgcaaata
    21841 aaagattatt ttgaaataat cctagcgcgt gaagatgttt ctagaggcaa accttatcca
    21901 gatatctata ataaagcagt acaaaaacta ggattacaaa aaaaacaact gcttgtagta
    21961 gaagacagcg aaaaaggcat tgctgccgcc aaagcggcca atctgacagt ttttgccatt
    22021 accgactacc gatatggcat tgatcagagt caagctgatc acaagataga tcatttagga
    22081 caactgtgtg taaaaatcgg ttgttttgga tcgtgaagta acgcaactaa ctgatcattg
    22141 atgatacttc aagacactta agaatacgtc taggactttc tacagaccaa taacaagaat
    22201 acgtttatgt gtttttactg ttttttagct acctatttac aatatgacac tgaaaagagt
    22261 actatgttta agttattatc aaaaaaaccg tcgcataaga tcacctagaa aaggattatg
    22321 atttttgtga tttggatgcg atcattagtc gttgaccatc tttatgtggc aggagatatg
    22381 tttaaccgtg gtcattattt ggatttgttt ttagattggc tagtgagtaa atatagaagg
    22441 atcataatac tgctttgaca aaggcagtat ctgagtccat gagttgcacg ggtaatgtga
    22501 ctcggttttg gttaggtata ataatatttg gaagtgttat gctgcttgtc ttcgtaggtc
    22561 cattgcttat agtcagactt actttagagc tgagctgact gtctagacaa gacgtgatgg
    22621 agatgtgatt tctgaccaag tagaggtaac cagaaaaggg acttttacga tgtaattgaa
    22681 tttacttgtt gcattcttgt gcatgttaag agagaaaacc cagataaatc aggaagtaaa
    22741 atggttatgt ttgattagaa ttgtccttct ttttccttga agtcttaact tattttgatt
    22801 atgatagtag tatgactatt aaggcagaaa ttaaggcact cgccaaagaa attggtatct
    22861 ctaaaattgg ttttacgacg gcagataact ttgattattt ggaaaagtca ttgcgtgctt
    22921 ctgtggaaga ggggcgcaat tcaggatttg aacataaagt catggaggat cgtatctacc
    22981 ctgaaaggct tttagaatcg gctaaaacga ttatttcaat tggcgttgct tatcctcaca
    23041 aacttcctca gcaacctcaa aaaacacctt ataaacgtgg aaaaattaca cctagttcgt
    23101 gggggcttga ttatcattat gtggtcggcg aaaagttaga cagactatca aaaggcattg
    23161 aagagctgtg tcgagatttt cctttgcaac aaaaagcaat ggtcgatact ggagctttag
    23221 ttgatactgc agttgcccaa agagcgggta ttggttttat aggaaaaaat ggtttagtta
    23281 tttctaaaga atatggctct tatatgtttt tgggagaatt aattaccaat ttagagatcg
    23341 agccagacaa gcctgtcgat tatgattgtg gtgactgtcg tcgttgtcta gatgcctgtc
    23401 caacttcttg tttaattggt gatggctcaa tgaatgccaa gcgttgtcta tcatttcaaa
    23461 cccaagataa gggaatgatg gacatagagt ttcgaaaaaa gattaaaaca gttatctatg
    23521 gttgtgatat ttgccaaatt tgctgtcctt ataacaaggg tataaacaat tcaccagcta
    23581 cagagattga tcctgagttg gctcaaccag aattaatacc atttttgagt ttatcaaatg
    23641 gacaatttaa agaaaaattt ggtatgattg ctggaggttg gcgaggtaaa aatattttac
    23701 agcgtaatgc cattattgcg ctagcaaatg ctcatgataa aaccgcagtg gtcaaattaa
    23761 tagagattat tgataaaaat aataacccta ttcatactgc aacagctata tgggcattgg
    23821 gagaaattgt caaaaaacca aacgatgaga tgctggcgtt tatgagtcat ttaaccttaa
    23881 aagatgaaga tagccaaaaa gagttggaat taatccgtcg taaatggcaa gtttaagcct
    23941 tttatggtat ttttaagaac cttatgataa aataaaacag attaacaaag attggagaaa
    24001 tctcatggaa gtggctgaaa ttcgccaaaa aatagtagaa aataaagaga agttgactag
    24061 cttcaggagg tctctttgac ttagatcgtt tggaagagga gattgctctt cttgaaaatc
    24121 acatgactga gccagacttt tggaatgaca atattgcagc gcaaaagaca tctcaagaac
    24181 taaatgagtt aaaaggtaag tatgatactt tccataatat gcaagaatta tctgacgaaa
    24241 cagaactctt acttgagatg cttgacgaag atgattcttt gaaagaagaa ttagaagaaa
    24301 atctaatgca gctagataag ataatgggtg cttatgaaat gacgcttctc ttatctgaac
    24361 cctatgacca caataatgct atcttagaaa tccatcctgg ttcaggagga actgaagcgc
    24421 aagattgggg agatttactc ttacgaatgt atacccgttt tggcaatgct aatggtttca
    24481 aagtagaagt attggattat caagcaggag atgaagctgg tattaaatcg gttaccctct
    24541 cttttgaagg ccccaatgct tatggtttgt tgaaatcaga aatgggagtt catcgcctcg
    24601 ttcgtatatc accttttgat tcagctaaac gtcgtcatac ttcatttgct tcagttgaag
    24661 tgatgccaga gttagatgat acgattgaag tagaagtacg tgatgatgac attaaaatgg
    24721 atactttccg ttccggagga gctggtggtc agaacgtcaa taaagtatca acaggtgttc
    24781 gtttgacgca tattccaact ggaattgtgg tatcgtctac cgttgaccgt actcaatatg
    24841 ggaaccgcga tcgcgctatg aagatgttgc aggctaagct atatcagtta gaacaagaaa
    24901 agaaagcaca agaagtagat gctctcaagg gtgataaaaa agaaatcact tggggaagtc
    24961 agattcgttc ttatgttttc accccttata cgatggtgaa ggatcatcgt actaactttg
    25021 agcttgctca ggtagataag gttatggatg gagaaatcaa tggctttatt gatgcctacc
    25081 ttaagtggcg cattgaagac taaaaataat aaaggagaaa catggcacta atagaaatgt
    25141 ctggtgttac taaaaaatac cgccgctcaa cgaccgccct cagagacgtc aatgtttctg
    25201 ttaatcaagg tgagtttgtt tatctcgtag gcccatcagg tgctggtaaa tcaactttta
    25261 tcaaactcct ttaccgtgaa gaacaactga caactggtaa gctatatgtg ggtgaattca
    25321 atttaactaa actaaaagca cgtgatgttc cgattcttcg tcgtcacatc ggagtagttt
    25381 ttcaagatta caaactgcta ccaagaaaaa cagtctttga aaatgtagct tacgccatgg
    25441 aagttattgg tgaaaagcgc cgccacatta aaaaacgcgt gccagaggta ctcgatttag
    25501 ttggcttgaa acataagatg cgttcttttc caagtcagct atcaggaggg gagcagcaac
    25561 gtgtggccat tgcgcgtgcg attgttaaca accctaaatt attgattgca gatgaaccga
    25621 cagggaattt agatcctgag atttcatggg aaattatgca gttacttgaa cgtattaatg
    25681 ttcagggaac aactatctta atggcgacac acaacagtca tattgtgaat acatttcgtc
    25741 atcgtgttgt tgctattgaa gatggtcgca tagtacgtga tgaagaaaaa ggagattatg
    25801 gttacgatga ttagatactt tttccgtcat atttgggaat ccattaaaaa tcttaaacgc
    25861 aacttttgga tgacatttgc ttcagttagt atggtggctg ttacattgac tttagttggt
    25921 gtttttgcgg cgacattgtt gaatatacag cgtgttgctt cgggtgttga aaataatgtc
    25981 catatcaata cctacttaca agttgattca actgatgctg caaaagttat tcaaaatact
    26041 gccggtgaac ctgttaataa cgataactac cacagtgttt acgacaaaat tgctcagata
    26101 aaaggtgtca aaaagattac attttctagc aaggatgaac aattgaaaaa attgcaagaa
    26161 accttaggtg atgtttggaa tatgtatgac caagacacta atccgctcca agatatctat
    26221 cttattgaga cccagacgcc taaacaagtt aaggcgatca ctaaaaagat cagaacgatt
    26281 gaaggcgtag aagccgcaga ttatggaggg attaactccg ataaactatt taagttttca
    26341 acattaattc aaacttgggg gttgatcgga acagcaatgc tattatttgt agctgtcttt
    26401 ctcatttcaa acactattcg tatgactatt atgtctcgta aacgcgacat tgaaattatg
    26461 cggttagttg gtgctaaaaa ttcttatatt cgagggcctt tcttttttga aggggcttgg
    26521 gttggcttgt taggagctgt tttaccatct cttctgattt attatggata tgatcttgtt
    26581 tataagcatt ttgcacaaga attacaacgt aataatctct cgatgtatcc gcttgatcct
    26641 tatgtatatt acctgattgg tgctttgttt gtcataggta ttatgattgg ttcgcttggt
    26701 tcagtgcttt ctatgagacg ttatttaaaa ttctaaaaaa agcgctgctg acgaaacgta
    26761 gcgaccctca aaagttggac ctcttatgtt attccaagga cttcgttttg tattgcacag
    26821 gactggtcct tttcattttg ttttgattca tttgtttatt tgtaataggc aatatagttt
    26881 aaaatagcag tttctaaggt ttcaagagaa gaaaagcacc ccaaaagtta gatgtttgat
    26941 gtatctaact tttggggtgt cattcaaaat ttagtggctc ttttttagta aaatactatg
    27001 atttcagttt taggataacc tcaaacagta tctaaaatag ctatgtcaat gaaaaaaggg
    27061 gttagcattt ttttcgtgac aaatggtagt agaaggacca tgcccaggat aaactcggta
    27121 atgattaggt aaggtgaata gttcttggcg aataccagta atgaggtcct caaagttact
    27181 ggtaggtaag tcagtacgac cgatagtttc acgaaataga gcatcgccag taacgactaa
    27241 ttcatctgag tggaaaacaa atgagactcc tccccaagaa tgaccaggtg ttggtaaaac
    27301 tgtgaattca aaaccattta gttgataggg ttgctttaat ttaaaaaagt tctctgccgg
    27361 tcttgctata acagtaatga tatcatcatg acggcctaac ccagataaat tatcatctgg
    27421 ggaagatagc caagcggctt ctttttctga aacataaaca ggtggatgat caaaagcatc
    27481 tctgaccaaa tctaaactaa aaatatgatc ataatgagta tgcgttaaga ggatagccac
    27541 taaaggtttt tcaaaggatt taattttagc aatgatttct tggccgttac ttcctggatc
    27601 aatgaggata acagcttgat cattaacgag gtaataagta ttttcaccag caatgtggtt
    27661 tattgtttta tagattttca taaggatagt gtaccaaaaa atcaaggctt tgttaaaaaa
    27721 agagtggcgg aaaataaatg gcaattagtt tcagaaaata tgagatctca cagcaatttc
    27781 ttgacaccgt tttcataaag gtgtatcata aaagtaatca ataagccaag cctaaagctg
    27841 aacttagttt aagaacactg actttttgag agcaacctaa tcggttgact aaaaaatatg
    27901 aggtggaaga tatgtcaaaa gttgctattg ttactggtgc tggtcaagga attggatttg
    27961 ctattgcgaa acgtcttcat gcagacggct ttaaaatagg cattttagac tataatgaag
    28021 agactgctca ggctgcggtt gataaactat cacctgagga tactgttgca gttgtagcag
    28081 atgtttcaaa acgtgaccaa gtttttgatg ctttccaaaa agttgtagat acttttggtg
    28141 atttgaatgt tgttgttaac aatgcaggtg ttgccccaac aacccctctt gacacgatta
    28201 ctgaagagca gtttgaaaag gcttttgcaa tcaatgtcgg aggaacgatt tggggaagcc
    28261 aagcagctca aaaacatttt agagaattag gtcatggcgg aaaaattata aatgcaacgt
    28321 cacaagcagg atgtgaaggg aatcctaatt tgactgttta cggtggtaca aaatttgcag
    28381 ttcgtggtat tacacagact ttggcaaagg atttggcatc agaaggaatc acagtcaatg
    28441 cttacgcacc aggtattgtt aaaacaccta tgatgtttga tattgcccat gaagttggta
    28501 aaaatgcagg caaagatgat gaatggggta tggagcaatt tgcaaaagat atcactttga
    28561 aacgcttgtc tgaaccagaa gatgttgcta atgcagtagg cttcttagtg ggagatgatt
    28621 caaattatat cactggacaa acaatagttg tcgatggtgg tatggtattc cattaaaaat
    28681 gattaatact gacactgtga gtttcactca cagtgttttt tatatttctt aaaaaattat
    28741 cctatcttga ttattggagt gatggcacct ttgaggtata gtcatgtttt gttttataga
    28801 tatagcgtgc tataatagac ttactatgac ccagaaaaaa cttagaaaat atgcagtagt
    28861 ggacttggag gctactggag caggtcccaa tgcttctatt attcaggttg ggattgttat
    28921 tatccaagga aataaaatta ttgatagtta tgaaacagat gttaatcctc atgaatcttt
    28981 ggatgagcat attgttcatt tgacaggtat tacggataag cagttggcta aagctccgga
    29041 ttttggtcaa gtggcgcatc acatttatca attgattgaa gattgtattt ttgttgccca
    29101 caatgtaaag ttcgatgcaa atttattggc agaagctctt tttttggaag gatatgagtt
    29161 aacaatacca cgtgttgata ctgttgaatt agcccaacta tttttccctc gctttgaaaa
    29221 gtataacctt agtcacctat ctaggcagct caatattgat ttggcagaag ctcatactgc
    29281 tattgcagat gcaagagcta cagctatact gtttttaaga cttttacaaa aaattgagag
    29341 ccttccaatt gagtgcttag aaagcttatt agcctattca gatagcctgc tatttgaaac
    29401 agcaatggtc attcaagaag gattagccaa ggccaaacct tatgatccca acaaatacat
    29461 taaaatcaga cagattctct taccaaaggg ctcaaaagct ctcaagcctt atcaaatatc
    29521 aaaaagcttc cctattaata tggcactatt aggtctggaa gaaaggccta aacagactca
    29581 atttgctcag ttaattgacg aagattacca tcagggagta gctagtttta ttgaagctca
    29641 gacaggtatt ggaaaaacct acggctacct gctacccctt ttggcaaaag aagatcaaaa
    29701 ccaaatcatt gttagtgtgc caaccaaact tcttcaagac caattaatgg ctggtgaagt
    29761 agctgctatt caagaacaat ttcacatcgc ctgccatagt ttaaaagggc ctgccaatta
    29821 cctaaagcta gatagctttg cagatagttt ggaccaaaat gaccagaacc gtttggtgaa
    29881 tcgttataaa atgcaattat tggtttggct cttagaaact aagacaggag accttgacga
    29941 aatcaaacaa aagcagcgct ttgccgctta ttttgagcag cttaagcacg atggagacat
    30001 taagcagtct tctgaatttt acgattatga tttttggaga gttagttatg aaaaagccaa
    30061 aacagcccgt ctcctgatta ccaaccatgc ttatttttta caccgtgttc aagatgacaa
    30121 ggactttact agaaacaagg tcttggtatt tgatgaggcc caaaagctga tgctccaatt
    30181 agatcaatta tcacgtcatc agcttaacct gacggttttt ttacaaacaa tacaggccaa
    30241 gttaagcaac cctttacctc ttttagaaaa acgcttattg gaaagcttgt cgtttgaact
    30301 gggacaagtg tcaagtgatt actatcaaaa taaagagcac cagcttgctc atgattggtc
    30361 tcgtatagct ggctacgcca aagaattaac aggagcagat tatcaagagt tacaagcctt
    30421 ttttgctacc tcagatggtg actactggct tagtagcgaa aagcaagagg agaagcgagt
    30481 gacttatcta aacagtgcta gtaaggcatt tattcatttc caacagctct taccagaaac
    30541 ggtgaaaact tattttgttt ctgccacttt aaccatcagc tcagaagtaa ccttggcaga
    30601 cctattaggt tttgaagagt atctctatca tgtcattgaa aaggataaaa agcaagacca
    30661 gttggtgctt gttgatcaag aggcgcctat cgtgacagaa gtcagtgacc aaatctatgt
    30721 ggaagcaatt gcaaaacgaa tcgaaagctt gaagcaagag ggttatccta ttttagtgct
    30781 ttttaattct aaaaaacact tgctgttggt ttcagactat ctagaccaat ggcaagtgcc
    30841 tcacttagcg caggaaaaga atggaacagc ttataatatt aaaaaacggt ttgatcaagg
    30901 agagcaaact attttgcttg gtttaggttc tttttgggaa ggagttgatt ttattcaagc
    30961 ggatcgtatg attaccctta tcgcacgatt gccctttgat aacccagagg atttctttgt
    31021 taagaaaatg agtcattatc tattggaaaa aggtaaaaat cctttcagag attacttctt
    31081 gccaatgact attttgcgat taaaacaggc tattggtcgc acgatgcgtc gacaagatca
    31141 aaagtcagtg gttattattt tggatcgtcg tctccttaca aagtcctatg gacaagttat
    31201 tttggaaggt ctcggtcagg aatttttgat ttctcaacaa aattttcacg attgtctagt
    31261 agaaacggac tgttttctga tataatggaa aggatctatt atatcagaaa aatttttaat
    31321 ggcgttaagc acaatcaact aacatttaaa ttagtttgaa cttttattat gctcttttag
    31381 acaactgttc aaatgttttc gaattgtttt tttgataagg acaataaatg aacaaatttt
    31441 tggttttagt aaacccaatt actgttcttt tcattaatgt cagttgctat caaaacagct
    31501 tgtcatagtt cgtgcgatca gtagcgagta ttggtaaaac tgaaaccgta gattatgaaa
    31561 aaatgatctg ttgatcatta attaatctga agataagaag tcgataaaaa ggagatacga
    31621 tgcccaaact atcaaagcga gttttagaga tgaaagagag tgttactctg gctgcaggtg
    31681 ctagagctaa ggctttgaaa gcgcagggtc gtgatgtact gaatttaact ttaggagaac
    31741 cagatttttt tacacctaag cacattcaag acaaggcgat tgaatctatt caaaatggta
    31801 cggctagctt ttatacaaat gcttctgggc ttccagaatt aaaagctgcg attgccacat
    31861 acctgaaaaa tcagtatggg tatcacttgt ctcctgatca gattgtggca ggaacaggtg
    31921 ccaagttcat cctttatgcc ttttttatgg ctgttttaaa tcctggtgac caagttctca
    31981 ttccaacacc atattgggta tcttattctg accaagtaaa aatggcagaa ggtcagccga
    32041 tcttcgttca aggactagaa gaaaatcaat tcaaggtaac tgttgaccag ctggaaagag
    32101 caaggacaag taagactaaa gttgtcctta tcaattctcc ttccaatcca acaggcatga
    32161 tttatggtgc tgaggaatta agggccattg gagaatgggc ggtgcacaac gatattctta
    32221 ttctggcaga tgatatttac gggtccttag tctataacgg caatcagttt gttcctattt
    32281 caacactctc agaagcgatt cgtcgtcaaa ccattacggt caatggcgtg gctaaaagtt
    32341 atgccatgac aggctggcgg gttggttttg cagcaggtga accagagatc atttcggcaa
    32401 tgagtaagat catcgggcag actacctcta acctgacaac cgtttcacaa tatgctgcta
    32461 tcgaggcttt ctgtggtagt cagtcatcac ttgaagagat gcgattagca tttgaagagc
    32521 gccttaatat cacttatcca ttgttgtgtc aggtccctgg gtttgaggtt gttaaaccac
    32581 aaggagcttt ttacttcttt ccaaacgtta agaaagccat ggaaatgaca ggtttttccg
    32641 atgtgacaag ctttgctaat gctattttag aggaagtcgg attagctgtt gtgagtggag
    32701 caggctttgg cgcaccggaa aatgttcgtc tgagttatgc tacagatatc gaaaccctta
    32761 aagaagctgt tcgtagactg catgtcttta tggaaagtaa tgaaattaat taaattaatt
    32821 aaataaaaat agagagaaac ttatgtcaaa aaaacttatt tcaattgttg atgttaaaga
    32881 ttatgttggt caagaagtta ctattggtgc ttgggttgct aacaaatcag gtaaaggtaa
    32941 gattgcgttt gtacagttgc gcgatggttc ggcttttttc caaggtgtcg cttttaaacc
    33001 aaacttcatt gaaaaatatg gtgaagaatc aggtcttgaa aaatttgacg ttattaaacg
    33061 tctcaaccaa gaaacatctg tttatgtaac agggattgtt aaagaggatg agcgttctaa
    33121 atttggctat gagcttgata ttactgacct tgaaatcatt ggagagtcac atgaatatcc
    33181 tataactcct aaagagcatg ggacagactt cttaatggac aaccgtcatc tttggttgcg
    33241 ttctcgtaaa caaatggctg ttatgcaaat tcgtaacgct attatttatg caacttatga
    33301 attctttgac caaaatggtt ttatcaaatt tgatagccca attttatcag aaaatgcagc
    33361 agaagattca acagagttat tcgaaacaga ctattttggg aaaccagcat ttcttagcca
    33421 atctggtcaa ttataccttg aagctggagc aatggctcta ggccgagttt tcgactttgg
    33481 tccagtcttt cgtgctgaaa aatctaaaac acgtcgccat ttaacagaat tttggatgat
    33541 ggatgctgag tattctttct tatcacatga ggaatcactt gaccttcaag aagcttatgt
    33601 taaagcattg atccaaggcg ttctagatcg tgcgcctcaa gcacttgata ttttagaacg
    33661 tgatgttgag gctctcaaac gttatatcac agaaccattc aagcgtgttt cttatgatga
    33721 tgctattaca cttcttcaag agcatgaagc agatgaagat acagattatg aacatttaga
    33781 gcatggtgat gactttggtt ccccacatga aacttggatt tctaattact ttggagtacc
    33841 gacatttgta gtgaattacc cagcaagctt taaagcattt tatatgaaac cagttcctgg
    33901 aaatccagaa cgcgttcttt gtgctgatct tttagctcca gaaggttatg gagagatcat
    33961 tggcggctca atgcgtgaag acaactatga tgctcttgtg gctaaaatgg atgaactagg
    34021 tatggataaa tcagaatatg acttttacct tgaccttcgt aaatatggct ctgttcctca
    34081 tggcggtttt ggtataggta ttgaacgtat ggtaactttt gttgctggta ccaaacatat
    34141 tcgcgaagct attccattcc cacgtatgtt acatcggatt agaccctaat aatacaaaaa
    34201 agttcatgtc atctatgaac tttttgtatt ggtaagaggt gagtgtgtta taaaaaaatc
    34261 aatatgtcct aaaggagaga taagaaatag tagagtttga acctacatcc tttgtgaaga
    34321 taaattttgg aagtttagta gatcagttag cagataagac aatatagcct tgctcaaggg
    34381 atattttata gacaagtatt tggactacga ttatcaaata gacagtctca tttgatacta
    34441 aaaaggtctc gtctattcat ataataggag agttacggga gttattatta aaattagctg
    34501 atttttacag ttcaaaatgt gttaccactt tttcacttct tagctttctt atgtatgtgg
    34561 tataatgaag gtggacggtt cgatagagaa agggaaattg taaatgtcag acaaacacat
    34621 taatttagtt attgtgacag gaatgagcgg cgctggaaaa acagttgcca ttcagtcttt
    34681 tgaggatcta ggctacttta ccattgataa tatgccccca gccttggttc caaaattttt
    34741 agaattaatt gaacaaacca atgaaaatcg tagggtggct ttggttgtcg atatgagaag
    34801 tcgtttgttt ttcaaggaaa ttaattctac cttagatagt attgaaagca atcctagcat
    34861 tgattttcgg attctttttt tggatgcaac ggatggagaa ttggtgtcac gctataaaga
    34921 aaccagacgg agccaccctt tggctgcgga cggtcgtgtg cttgatggta ttcgattgga
    34981 aagagaactc ctatctcctt tgaaaagcat gagccaacat gtggtggata caacaaaatt
    35041 gacccctaga caattgcgta aaaccatttc agaccagttt tctgaagggt ctaatcaagc
    35101 ctctttccgt attgaagtga tgagctttgg gttcaaatat ggtcttcctt tggatgcgga
    35161 tttggttttt gatgtgcgtt ttctacccaa tccttattat aaggtagagc ttcgtgaaaa
    35221 aacaggacta gatgaggacg tttttaatta tgtgatgtct cacccagaat cagaggtgtt
    35281 ttacaagcat ttgttaaacc ttattgtccc tatcttaccg gcttaccaaa aagaagggaa
    35341 gtctgtcttg acggtggcta ttggctgcac aggaggccaa caccgcagcg ttgcctttgc
    35401 ccattgcttg gcagaaagtc tggcaacaga ttggtcggtt aatgaaagcc atcgtgatca
    35461 aaatcgtcgt aaggaaacgg tgaatcgttc atgaaaaatc ctaaaatgac tgttataggt
    35521 gggggtactg gcatctccat tatcctaaaa agccttcgta atgaagcagt tgatattact
    35581 gctgtggtca ctgttgcaga tgatggtggt tcctcaggag aacttcgtaa tgccatgcaa
    35641 ttaaccccgc caggagactt acggaatgtc ttgttagcga tgagtgacat gccaaaattt
    35701 tatgagcggg ttttccaata ccgttttaac gagagtgatg gagccttggc tggtcaccct
    35761 ctaggcaatc tcattattgc tggtatctct gaaatgcaag gctcaaccta caatgccatt
    35821 caaattttaa ccaaattttt ccatattaca ggtaaaattt acccctctag cgagcaggcc
    35881 ttgacccttc atgctgtttt taaagatggg cacgaagtag caggagaaag ttctattgcc
    35941 aaatatcaag gcatgattga ccatgtctat gtgaccaaca cctacaacga ccaaaagcct
    36001 caggccagtc gtaaggtggt tgaggctatt ctagaaagtg acatgattgt cttgggacca
    36061 ggctcactgt ttacctctat tttacctaat ttggtcattc cagaaattaa agaagctttg
    36121 cgccagacta aagcagaagt ggtgtatatt tgtaatatca tgacccagta tggtgaaaca
    36181 gaacaatttt cagatgcaga ccatgtggct gttttaaatc agcacttagg aagagatttg
    36241 attgatacgg ttttggtaaa tgtggctaag gtgccgcagg cttacatgaa ttctaacaaa
    36301 tttgatgaat acctcgttca ggttgatcac gactttgctg gcctttgcag ggctgctaag
    36361 cgtgtgattt cgtcttattt tttacggttg gagaatggcg gagcttttca cgatggtaac
    36421 ttagtggtgg aagaattaat gaatttagtg aggatagtca agcaatgagt tttacaacca
    36481 aggtcaaaga ggaattaatt cacttgtcca caggtgacaa caatgaattg gccgccatta
    36541 tcaaattatc aggcagcttg ggcttagctc accaaagcct tcatttatcc attaccactg
    36601 aaaatgctaa aattgcccgc tacatttatt ctcttattga agacgcctat gttatcgtgc
    36661 cagaaatcag gtatcatcaa aagacgaacc tgcgcaaaaa ccgtgtttac accgtctatg
    36721 ttgagcaagg tgtggaaacc attttagccg atttgaaatt agcggactcc ttttttggtc
    36781 tggaaacagg catcgaacct caggttttat cagacgataa tgctggccgt tcttatctta
    36841 aaggggcttt tctagcggca ggtagcatca gagatcctga gtcaggcaag tatcagttag
    36901 aaatctattc agtttatctt gatcatgctc aagatttagc tcaactcatg caaaaattta
    36961 tgctagatgc caaaaccatc gagcataaaa gcggtgcagt tacttatgtg caaaaggcag
    37021 aagatatcat ggacttttta attataattg gtgccatgtc ctgcaaagaa gactttgaag
    37081 ccatcaaatt acttcgagaa gctcgaaatg atattaaccg tgccaataat gcagaaacag
    37141 ctaatattgc caaaactatc agtgctagca tgaaaaccat taataatatt attaaaatca
    37201 tggacacaat tggtttagaa agtttaccga ttgaattgca acaggtagcc cagcttcggg
    37261 ttaagcatcc agactattcc attcaacaag ttgctgatgc tcttgagttc ccaatcacca
    37321 agagcggggt caaccatcgc ttgcgtaaaa tcaataaaat tgcagatgac ttatagaaca
    37381 tttttatcgt atgagccttt gttcatacga tttttttgtc taaaagtcgt tttccattgt
    37441 ttttttgaag tgtctgatgt tctgtgatat gataaaaggg ataataacgt ttgtaaagga
    37501 gactgataat ggcatgtaca actatactcg tcggtaaaaa ggcatcttat gatggctcaa
    37561 ccatggttgc tcgaacagaa gattctcaaa atggtgattt cacgcctaaa aaaatgattg
    37621 tggtgaaacc agaagatcaa ccgagacatt accgttcggt gcaatcttcc tttgaaatgg
    37681 acttaccgga caatcccatg acttacacgt ctgttcccga tgcgcttggt aaagatggta
    37741 tctgggcaga agcaggcgtg aacgaggcta atgtggccat gtcagcaact gaaaccatca
    37801 ctaccaattc tcgtgtttta ggggcagatc ctctagtagc ttctggtatt ggtgaggagg
    37861 acatggtgac cttagtgctc ccttatatcc gttctgcgcg tgaaggggtt ttgcgccttg
    37921 gtgccatttt agaagactat ggcacttacg agtcaaatgg tgtggctttt tcagatgaac
    37981 atgacatttg gtggctggaa acgattggtg gtcatcactg gattgcaaga cgggtgccag
    38041 atgatgctta tgtcaccaat cccaatcaat ttggcattga ttattttgaa tttaacaatc
    38101 ctgaagatta cctttgctca gctgatttaa aggactttat tgacacgtat cacttagatt
    38161 taacctataa ccatgagcat tttaatcccc gttatgcctt tggtagtcaa cgtgacaaag
    38221 accgtcacta taatacgcca cgtgcttgga tcatgcaaaa attcttaaac ccagaaattg
    38281 tgcaagaccc gcgcagcttt gcccttgctt ggtgtcaaaa accttaccgt aaaataacag
    38341 tagaagatgt caaatatgta ttgagtagtc actatcagga cacggtttat gacccttacg
    38401 gttcagaagg aactcctgtt agtaagaaag tctttcgccc tattggcatt aaccgtacca
    38461 gccaaaccgc tatcttacac attcgtccta ataaacctca agaaattgcg gctatccagt
    38521 ggatggctta tgggtcaatg ccatttaata ccatggtgcc ttttttcaca caggtgaaga
    38581 ctattccaga ttattttgcc aacacttacg aaaatgtgtc taccgacaat ttctattgga
    38641 ccaaccgtct gattgcggct ttggcagatc ctcactacaa tcatcatgaa actgatttgg
    38701 acaattactt ggaagaaacc atggcaaaag gtcatgccat gttacatgct gtggaagcac
    38761 agttattggc tggtgaaaca gtcgatttgg aagaggaaaa tcaaaaaatg agtgactatg
    38821 tgcaaggaga aacgcagacg ctgttgaaca agattctctt tgacgctagc aatctaatga
    38881 ccaatcgttt cagtttgagc gattaaaagt gaagctaagg ctgagcaact gcttagcctt
    38941 ttttacgata actttttagg aaaagtaatc gcaaaaagac aaaaacttgg aaaaaaaatc
    39001 aaagtatgct atacttaact ggtcaatttt taaccagtta ataacaaagg aggaatcatg
    39061 aaaaagaaaa ttcttttaat gatgagttta atcagtgtct tttttgcttg gcaacttact
    39121 caggcaaaac aagtcttagc agagggtaaa gtgaaggtgg tgacaacttt ctatcctgtt
    39181 tatgaattta caaaaggggt tattggtaat gatggcgatg tttccatgct tatgaaagca
    39241 ggaacggaac ctcatgattt tgagccttct acaaaagaca ttaaaaaaat ccaagatgca
    39301 gatgtatttg tttatatgga tgacaatatg gaaacttggg tttctgatgt gaaaaaatca
    39361 ttgacatcta aaaaagtgac catcgtcaag ggaactggta acatgctctt ggtagcagga
    39421 gttggacatg accatcacca tgaggaagct gacaaaaagc atgagcataa taaacatagc
    39481 gaagaaggac acaaccatgc ttttgaccca cacgtgtggt tgtcaccata ccgtagcatt
    39541 acggtcgttg aaaatattcg cgacagtctt tcaaaagctt acccagaaaa agcagagaac
    39601 ttcaaagcca atgccgctac ttatattgaa aaattaaaag agcttgacaa agactatacg
    39661 gcagcacttt cagatgctaa gcaaaagagc tttgtgacac aacacgcagc ttttggttat
    39721 atggcacttg actatggctt gaaccaaatt tctattaatg gtgtcacacc agatgcagaa
    39781 ccatcagcaa aacgtattgc tactttgtca aaatacgtta aaaaatatgg tatcaaatac
    39841 atttattttg aggaaaatgc gtcaagtaaa gtcgcaaaaa ccctagctaa agaagcagga
    39901 gttaaagcgg ctgtgcttag tccgcttgaa ggtttgactg aaaaagagat gaaagctggc
    39961 caagattact ttacggtcat gcgtaaaaac cttgaaacct tacgcttaac cactgatgtg
    40021 gctggtaaag aaattcttcc agaaaaagac acgactaaga cagtttacaa tggttatttc
    40081 aaagacaaag aagtcaaaga tcgtcaatta tctgactggt caggtagctg gcaatctgtt
    40141 tacccctatc tacaagatgg tactttagac caagtttggg actataaggc taaaaaatct
    40201 aaaggtaaaa tgacagcagc cgagtacaaa gattactaca ctactggtta taaaactgac
    40261 gtggaacaaa tcaaaatcaa tggtaagaaa aagaccatga cctttgttcg taatggtgaa
    40321 aagaaaacct tcacttacac atacgccggc aaagaaatct tgacctatcc aaaaggaaat
    40381 cgcggagttc gtttcatgtt tgaagctaaa gaaccaaatg ctggcgaatt caaatacgtt
    40441 caattcagtg accatgccat tgctcctgaa aaagcagagc atttccacct gtactggggt
    40501 ggtgacagcc aagaaaaatt acataaagag ttagaacatt ggccaactta ctacggttca
    40561 gacttatctg gtcgtgaaat tgcccaagaa atcaatgctc attaatctta actcactaag
    40621 caaatcttct tttaaggagg tttgcttttt ctttgtggag taaaaaaatt taataattct
    40681 caacattaat ttgacggaca cttatgatta taatatactt taagtggtta taacaagtta
    40741 gaggtgaata agatgccaaa agaacaacca ctctatctac agattgttga tgacttggaa
    40801 gtgaaaatca aaaagagcat gacagaaaac gataagttgt tgtcagaacg agaattaagt
    40861 gacctttacg gtgttagtcg tatcacgatt agactggctc ttaaggaatt ggaattacga
    40921 gacttaattt ataaaaagca gggcaagggg acttatgttt caggaatcaa agaacctgtc
    40981 actgatttat caagtactta cagctttaca gagcaaatga aaaaagtggg gaaaactcct
    41041 aaaacagaga ttctttcttt tgaacagtat caggtaacac cttacttgtc tggtctctta
    41101 gagtttgatc tcgatacaga agtttttgaa ttagaacgcc taaggattgc agatgatatg
    41161 cccttgatgt ttgaacgatc ctatattcct gcgcagcctt ttcaggggtt aagcattgcg
    41221 gacttgaagc gtaaagcttt gtacgatatc tttgcaaagg actatcaaga gacaatccgt
    41281 cttgcagaag aagagtttta tgccagcatt gccttggact atgaagcaga ccttttggga
    41341 atcaaaaaag gagatcctgt cttacatatt attcgtaaaa cttataacga taaaaatatt
    41401 ttgatcgaat ttactttcag tattgcaaga gcagaccagt ttaggtatag ggtacaacat
    41461 caccccaatg gttaaagaaa tgggaggtta atacatgttt acaaaaacgc aggaagcttt
    41521 ggaggctctt ggtgcagcta tcactaccaa ggaaattaaa caagaacccc gtttatggca
    41581 agaaaccatg acgttttttg aagaaacaag agattctctg gattcttttt taaagagagt
    41641 ttgtaaaagc gctaatggaa ataacgttca tgtcatcttt acaggtgcgg gtacatctga
    41701 gtacatcggt aataccattt gcccttactt gaagaaggtg gggaatcggc agtgctatct
    41761 ctttgagagt gttgcttcaa ccgatttggt tgcggcgcca gattattatc ttgctgagga
    41821 agagacggta ctattagtct cctttgctag gagtggtaat agtccagaaa gtgtagcggc
    41881 tgttaacctg gtcaatcaac tagtgccaaa tagttatcat ttaaccatta cgtgtgccaa
    41941 agatggagaa ctggcgaaaa aagcacagca agatgagcgt tcttaccttt atttgatgcc
    42001 tgaagacgct aatgatgctg gttttgccat gactggtagt tttacctgta tgatgctagc
    42061 ggctcttttg atttttgatg atgctaacag tatagctcag aaagaagctt atgtgactga
    42121 tatgattctt gctgggcaag ctgttattga ccaagaaaga cggctacaag agctagctga
    42181 tttaggattt gaacgtttag tttatctagg ttctgctggt ttagccaagt taacccaaga
    42241 agctcaatta aaaatgttag aattgacagc tggacaagtt gcgaccctct acgagtcctc
    42301 tatgggcttt aggcatggtc cgaaatcttt tattaatgac cgtaccttag tcattggatt
    42361 tgtcaataat gatgcttacg tcagacagta cgatttggac atgttagagg aaatccaagc
    42421 agatggcatt gcccttaaaa tcttggctct attgcaagga ggggatatca acttttcaga
    42481 ggaccaattt cgactagaca cccgtcactt attgccagaa gcttacttag cttttcccat
    42541 gattttagtc gcgcagacct tggccctctt aacggccgtt acattaggaa attcccctga
    42601 caccccatct gcgacaggaa cggttaatcg tgtggtcaaa ggagtaacga ttcaccctta
    42661 cccgactagt agtcgtcaat gcaacaaagc ttaaagcttt tgtgtagaag ccgtaaaacg
    42721 aaatgatttt gtgctagtag gccaaaagaa aaaccctcct gatacaggaa ggttttttgt
    42781 attgtcttgc ttattttgct gcgtttgcgt ctttgagacc gtattttttg ttgaagcggt
    42841 ccacacgtcc atctgcttga gtgaactttt gacgtcctgt gtagaatggg tgtgaatctg
    42901 atgaaatttc cacacggata agtgggtaag tttcaccttc aaactcaaca gtttctttag
    42961 aagcttttgt tgagccgcta aggaactggt aacctgtagt tgtatcaagg aaaacaactg
    43021 gacgataatc tggatgaatg tcttttctca tcttaaaaaa ttcctttctg ccatgacact
    43081 tgatgcatca tagttattaa ctattctagt gtaacaaaac ttgaatgact tgacaaggct
    43141 tttctttcct tattttttaa aaatcctaaa tctcttggca aacagcgatg agttctcgga
    43201 aaatagcttg attttcttct aaattagctg agttggctcc gctagcaagg ggatgccccc
    43261 ctccaccgtg acgcttagca atgccattaa taatcttttc tttactgcgc atacgcacac
    43321 ggtagttgcc gtcagttaac tcaacaaaaa tagcccaagc ttgaacgtta tcaattttac
    43381 caggagcaca gacaatggca gagctttctg ctagggtcac gtcaaaatgt tttaaggttt
    43441 cttggctgac aaggacataa gcagccccac tctcatcaat tgttaaatgc tcaaagacgt
    43501 agctttgcag ctttgctatt ttcaaaggaa acgaatccat ttgccttgaa atcgcagcaa
    43561 agtcgaactc gaaatgtctg agttggctag caatggaaag ggttttacta gtggttgagg
    43621 cataaagaaa tcgccctgta tcaccaacga taccagtgta taagagctta gcagccttgt
    43681 cagagagagt aagattctga ctaaaggcaa agtctgcaat gatttcactt gcgctagaag
    43741 cgcttgtgtc cacataatag aagtcaccat atacatcatc gttgggatgg tgatcaatct
    43801 taattaagca ctgccccagt gtgtagcgct catcatcaat ccttggtcga ttcgctgtat
    43861 ctgtaatgat gaccaaagcc tctttatagt ctttatcagt cacctgatcc atttggctaa
    43921 tccaagttaa actaggctca tcaaaaccag tcatcaaaac ctttttatct gggaaatttt
    43981 gtgcaataat ttctttcaag ccggcctgac taccaagagc atcagggtca ggattttgat
    44041 ggcgatggat aataatagtt tggtgagctt ttattttatc taaaattgtt tcaaaagttg
    44101 ttatcatgct ttaatctttc tttttcaaaa agaggaaaat aaccgtttaa cataatcttc
    44161 aaaaaacggt ttgtgtcata aggaggtgtg cgttatgtta agtggctaat gctagaattt
    44221 tttaagattg tcaaagctca taaattgaca ttttatctga aaatcatatc ctattttatt
    44281 atagcataaa agtaagctct agataatggt aaattaatct aggaagaaaa gaggttagtt
    44341 atcagttatg atactatcaa agctagtttt gcaaatgcaa gtgaaaaaat agtttttaag
    44401 tgtcttaagt aatcatatca actttctctt taaacaatta gtgcttttcc taaaaaagtg
    44461 tgctaaaata aacatagttt agtaattttg ggaggaattt atggcattag caaaaatcgt
    44521 ttatgccagc atgacgggaa atactgaaga aatcgctgat atcgttgcaa ataaattgca
    44581 agaattgggc catgatgttg acattgatga gtgcacaaca gttgacgctt cagagtttga
    44641 gaatgctgat atcgctgtcg ttgcgactta tacttatggt gacggtgact taccagatga
    44701 aatcgttgat ttttacgaag atttacaaga tttagattta gaaggtaaaa tctatggcgt
    44761 tgtcggctct ggtgacactt tttatgacta tttttgcaaa tctgttgatg acttttcaga
    44821 tcaatttgcg cttactggtg ccgtcaaagg tgcagagcca gtcaaagtag atttggcagc
    44881 agaagatgaa gacatcgatc gtttagaggc ctttgcagag caactctcac aggctgttaa
    44941 taatctataa aactatttag taaaaatgtc agggacttcc ttggcatttt tagattttta
    45001 acctaaaata aagggaatgt cacttcaggg taggaattga aaaaacaatc agcttcacct
    45061 tgcttctgat cctcttatta actataataa aaagataatc taatacatct agaaaaggaa
    45121 agttatgcgt ttagaagaga tacgacaaga aatcaatggt attgatcacc acttggttgc
    45181 cttattagaa aagcggatgg cacttgtaga gcaagtaaca gcttataaac tagccaatca
    45241 cttgcctgtc ttagatcagg cgagggaaaa tcagatccta gatagggttt cttatctcgt
    45301 taaagaccaa gcatttgagc cagctatcca tgagactttt aaaaccatta tgtctctttc
    45361 acggcagtat caaacgcaac gcttaacagg tggtgacatt aatgattaaa tcaattgcaa
    45421 cactgcctaa accctcctta aaagaagcgt taggactaat aggcttggcg cttcccatag
    45481 gggccacggt tggagtggtt gatgtgattt ttggtaaagg gcttttgttt ctttccgaat
    45541 atcgcgatca ccacctgttc ttgcttcttc cttttcttgc cctagcaggt cttgttatcg
    45601 tttttcttta cgataagtta ggcaaagagg ttcgtcaagg gatgggattg gtttttcagg
    45661 taggacatgg tcaaaaagat cagattcctc ctattctcat tcctcttatt ttgttctcga
    45721 cttgggtaac ccacttattt ggagcgagtg cgggtcgaga aggggtagcc gttcaaatag
    45781 gagctaccat ctctcattat tgtcagagat ttgtgactag tcaagaagcc gcacgacacc
    45841 ttttgattat ggggatggca gccggttttg caggactttt tcaaacgccg attgctgctg
    45901 tcgtatttgc ccttgaggtt ttgttggtag gaacgcttcg ctactgcgct ttattgcctt
    45961 ccttagttgc tgcttgcgtg gcttcttgga cctctcattc tttgggatta gagaaattta
    46021 cgattgttct tgaagaaaca ttgaccataa ctcccttaac attggttaaa ttaattgggt
    46081 taggccttat ttttggtctg gtgggaaata gttttgccta tttacttggc tggtttaaac
    46141 cttacctcag tcaaaagcta ccaaatcctt atttccggat tgcttttatc ggtgctttgt
    46201 tatctatctg tctgatgatt ggtcacgtcg gaagatatag tggtctagga actcatttga
    46261 ttgcggcagc tttttctggc caaactatcc taacttacga ctggctttta aaaatgatcg
    46321 tgacggtgat tagcttatct gcaggctttc aaggtggtga agtgacgcct ctatttgcta
    46381 ttggagcttc tttaggcatc gttttggccc cttacttagg tcttcctgta ctgttggttg
    46441 ctgcacttgg ttacaccacg gtatttggaa gtgcaacaaa taccttttgg gcccctatct
    46501 ttattgggat agaggtcttt ggtccagaga atgccctagc atattttgtc acctcggctg
    46561 cagcctatat ggttagtcac agacattcca tttacagtta tcaaaaagta gtcatgatca
    46621 atttaaaaga catgacggta aatcagatgg atttaaaaaa atagctttac aataaagaag
    46681 ctttttgtta gaataaatct cgtgtgtaat ggacacacga aaattacggc taatccgcta
    46741 agacaagtac ttaagattag taagatagga gaataaaaat gaatccatta atccaaagtt
    46801 tgacagaagg tcaacttcgc tctgatatcc ctaacttccg tcctggtgac actgttcgcg
    46861 ttcacgcaaa agttgtcgaa ggaactcgcg aacgtatcca gatctttgaa ggtgttgtta
    46921 tttcacgtaa aggtcaaggg atctcagaaa tgtacactgt tcgtaaaatc tcaggtggta
    46981 tcggggtaga gcgtacattc ccaatccaca caccacgtgt tgacaaaatc gaagttatcc
    47041 gccacggtaa agtccgtcgt gcgaaacttt actacttgcg tgcattacaa ggtaaagctg
    47101 ctcgtatcaa agaaattcgt cgttagtttg aaccgaaacg taacgtaata gaataaaaag
    47161 actagagtct ctagtctttt tatgtcgtcg tgacaatgtg acaattggtg attaacgcta
    47221 tgctcgtagg acactttgaa agttccttag cagttataat tagtatattg taataacaaa
    47281 atgaagcaaa ataaactttc agttatctga tatttcatct tgcattacct tattttctag
    47341 gttaaaatag aagacaaggt gaatataaga taggcccctt agttcaatgg atataacaac
    47401 tccctcctaa ggagtagttg ctggttcgat tccggcaggg gtcattattg tcactgaaaa
    47461 agcctttaca tcaaaggctt tttgttttat tccggtttta aaaggggcat aaaaggggca
    47521 gtttgtttat ttataatttc tttcatgttt acagttgtgt gactgtaaat agataatgtt
    47581 gtttttggat cgctgtgacc aactctatcc attatcgcat ttagcggtat ccctttttct
    47641 gctaaaaatg atatatgcga gtgtctaaat aagtgcgtgt gataatctcc gtaaattttc
    47701 aatcgcttat tgatgtgtgc atttaaaatt ggtaaacctt ttgaatatgg aaagctgtta
    47761 gcactctgct tgtgattaat ctatcgtatg ttaaaagtga catttaaatt aaatcatttt
    47821 ttatacatat atttcaacag gatttatcat attggaaaat agcggtgctt ctattggcat
    47881 tttactattg acaggaattt ccctgtcttt tgtctcctaa agaagatcag ctttgatttc
    47941 taacttgatt agagtgggct tggtactgtt tatgaattat cagtatatac tttctggaga
    48001 tcaaaaagga aaggaacagc taaagaggtg tatgtgttac cattagagga atagaacatc
    48061 gcaagactcg tttattcagt cattacgata cctgttttat ttgggaaata actataatat
    48121 taagtgaatt tgtgatataa tgaaaggtat gaattatcaa gattatatat gggatttggg
    48181 aggtacctta ctcgataatt acgagctttc aacccaagct tttgtccaaa cgctagcttt
    48241 tttcagcctt ccaggagatc acgatgctgt ttaccaaaaa ttaaaagaat caaccgctat
    48301 cgctgtggca atgtttgctc ctaatgagcc agaatttttg catgtgtata ggctaagaga
    48361 agcagacaaa ttggcacaac ccatttggtg tttgggagct aaagaaattt tggaaaagat
    48421 agcgacttca ggttcgcgaa attttttaat ttctcatcga gattgtcagg tgaaccaact
    48481 tttagagcaa gctgggttgc taatctattt tacagaagtc gtgacagctt caaatggctt
    48541 tgctcggaaa ccaaatcctg aaagtttgtt ttatttaaaa gaaaagtatg atattaatag
    48601 tggattagta attggagatc ggctaattga taaacaagca ggacaagcag cgggctttaa
    48661 taccttgctt gttgacggta gaaaaaacct attggagata gtaacgtaga tgattgaaga
    48721 aaataaacat tttgaaaaaa aaatgcaaga atacgatgcc agtcaaattc aggttctaga
    48781 agggctggag gctgtccgca tgcgtccagg gatgtatatt ggctcgacag ctaaagaggg
    48841 tttgcatcat ttagtctggg aaattgttga caactcaatt gacgaagcat tagcaggttt
    48901 tgcctctcat attaaagtct ttattgaagc agataattcc attacagtag tagatgatgg
    48961 ccgtggaatt ccagttgaca tccaagccaa gacaggacgt cccgccgttg aaacagtttt
    49021 tacagtctta cacgcaggtg gtaaatttgg cggaggcggc tataaggttt ctggaggatt
    49081 gcatggtgta gggtcatctg ttgttaatgc tttatcaaca caattagatg tgcgtgttta
    49141 taaaaacggc caaattcatt accaagaatt taaacgcggg gcagttgtag cagatcttga
    49201 ggtcattgga accactgatg tgactggaac aacggtacac tttacacccg atccagaaat
    49261 ttttaccgaa acgactcagt ttgattacaa tgttttagca aaacgtattc aagagttagc
    49321 ctttttgaat cgtggtttaa aaatttccat tacagataag cgctcaggta tggaacaaga
    49381 agaacatttc cattatgaag gtggaattgg ttcttatgtt gaatttttaa atgataaaaa
    49441 agatgttatc tttgaaacgc ccatctatac agatggtgaa ttagaaggta ttgcagttga
    49501 agtagccatg caatacacga ctagctatca agaaacagtc atgagttttg ctaataatat
    49561 tcatactcat gaaggtggaa cgcatgaaca aggctttaga gcggctctta ctcgggtcat
    49621 caatgactac gctaagaaaa ataaaattct taaagaaaat gaggacaatt tgacaggaga
    49681 agatgttcgt gaaggtttga cggcggtaat ttctgttaag catccaaatc ctcaatttga
    49741 aggtcaaacc aaaacaaaat tgggcaactc agaagtggtt aagatcacta atcgtctctt
    49801 tagtgaggcc tttcaacgtt ttcttttgga aaacccacaa gttgctcgta agattgtgga
    49861 aaaagggatt ttggcttcta aagctagaat tgcagctaag cgagcccgcg aagtcacccg
    49921 caaaaaatca ggcttagaaa tttcaaactt acctggaaaa ttagcagact gttcgtcaaa
    49981 tgatgctaac caaaacgaac ttttcatcgt cgaaggagat tcagcgggtg ggtcggccaa
    50041 atcaggtcgt aaccgagagt ttcaagctat cttgcctatt cgcggtaaaa ttttgaacgt
    50101 ggaaaaagca actatggata agattcttgc caacgaagaa attagaagtc tttttaccgc
    50161 tatgggtaca ggttttggtg cagattttga cgtgtcaaaa gctcgctacc aaaagctggt
    50221 tatcatgacc gatgccgatg tggatggcgc tcatattaga accttgcttt taaccttgat
    50281 ttaccgcttt atgaggcctg ttctagaagc tggctatgtt tatatcgccc agccacctat
    50341 ttatggtgtt aaggtcggta gtgagattaa agagtacatt cagccaggta ttgatcaaga
    50401 agaccaatta aaaacagctc ttgaaaaata tagtattggt cgttcaaaac caactgttca
    50461 acgttataaa ggtcttgggg aaatggatga ccatcaactt tgggaaacta ctatggatcc
    50521 tgaaaatcgt ttgatggcgc gtgtgacagt tgatgatgcc gcagaagcag ataaagtatt
    50581 tgatatgtta atgggagatc gtgttgaacc aagacgtaat ttcattgagg aaaatgcggt
    50641 ttatagtaca ctggatattt agtcaccttt ttagtttcac aaggaatctg ctaccaaaga
    50701 ggacgaattg actaaaaatc atgatgcatg atgccaacag ctttgttagt tagtacgtct
    50761 tcatcttgag ggacagcgtt aatgcatagg tattgagacc gccccttaat acctatgtta
    50821 gtccttatta agaaagcctt gtgagtcgct ggtacgagat tgttgaatta gtcaaatata
    50881 ttttgaaatg cattttaaag tatgttataa tcgtaatgtt atagtgtatt ttaaataaaa
    50941 ttttaataaa aggcgattga ggaatttcag tttttagtta ttactggaac aatgttgata
    51001 aatcgtgtct aaataataag gagattcaga tgtcaagcgg aattatcttg ctgattgtgg
    51061 ctatagtcct actagtgatt atcgcctatc tagtgggtgt catcatacga aagcgtaatg
    51121 attccctaat taccagtcta gaagaacgaa aacaggcctt gtttgctttg cctgttaatg
    51181 atgaaattga agaagtaaag tcacttcatt tgataggaca gagccaaacc tcttttcggg
    51241 aatggaatca gaaatgggta gacttaactg taaattcgtt tgcagatatt gaaaatcata
    51301 tttttgaagc tgaaaatttg aatgatacgt ttaattttat tcgcgccaag catgagatta
    51361 atagcgttga aagtcagctt aatcttgttg aagaagatat cgcttctatt cgtgaggcac
    51421 ttaatatctt aaaagagcaa gaagaaaaaa atagtgctcg tgtcacccat gctcttgatt
    51481 tatatgaaaa gctccaagct tctatttctg agaatgaaga taattttggt tcaactatgc
    51541 ctgaaattga caaacagatg aaaaacattg aaactgaatt ttcacagttt gtcgcactca
    51601 actcatcagg tgatcctgta gaagcttctg aagttctgga tagagcagaa gagcatacta
    51661 ttgctctagg gcagattaca gagcagattc cagctattgt cgccaagttg gaagatgatt
    51721 ttccagatca gttagatgat ttggaaacag gatatcgccg tttacttgaa gaaaactatc
    51781 attttccaga aaaaaacatt gaggcacgtt ttcaggagat tcgtgagtct attcgtgcca
    51841 attcatcaga gttagttaca cttgacttgg atcgtgctag agaagaaaac acgcatattc
    51901 aagaacgcat tgattctctt tatgaagtct ttgagcgcga aattgccgct tataaggtag
    51961 ctgctaaaaa tagtaagatg ctacctcgtt acctagcaca tgtgaaacgt aataatgaac
    52021 aactcaaaga tgaaattgca cgtttatcac gtaaatatat tctaagtgaa acggaaagtc
    52081 tgactgttaa ggcatttgag aaggatatta aagagatcga agacagtaca cttgctgttg
    52141 cagaacaatt tggtttacaa gaaaaaccat tttcagaact gcaagtgact tttgaacgca
    52201 gtataaagac gcttactaat gtcgagtcag gtcaaatgga tgtttttgca gcagttaaag
    52261 atattgaaaa aattgaatca caggcacgcc ataaccttga tgtttatgtt actcagcttc
    52321 atatgattaa acgttatatg gaaaaacgtc acttgcctgg aattccacaa gactttctta
    52381 gtgctttctt tacaacgagt tcacagttgg aagctttgat ggatgagctt agtagaggac
    52441 ggatcaatat tgaggcagtg tcacgtttgt cggaagttgc gacggttgct attgctaatc
    52501 tagaagattt aacctatcaa gtggttcaaa atgctacctt gactgaacaa ttactacaat
    52561 attctaatcg ctatcgttct tttgaagcag gagttcaaag tagttttgaa catgctttga
    52621 gacttttcga agtagaaaat gattatcagg cttcttttga tgaaatttct tatgctcttg
    52681 aaacagttga acctggggta acagatcggt ttgttaactc ttatgaaaaa acacgagagc
    52741 acattcgttt ttgatacttg aaagtcgtga tattctcacg actttttatt agctttttgg
    52801 accaatacgt gtttttgact agaatcttct ttttaatgat caaacgaaga agtagtaaca
    52861 gtgttttttg gtattgagag gatagttatt ttttcaaaaa tcttttccaa aaggatttgg
    52921 ttttttcagg aggttgtttg ctaagttgat cattttttgt ctgctttaag atgacttcta
    52981 aacgcgtttc ctttagattt attgcgtggt cggtatgaag gataaacgca aaaggtgaag
    53041 tcatatgcgt ttctgtaata atagtaacag gtaaatggtt ttcttttgct aatttcatat
    53101 agagtatttg aagttgaggt gccagcttgg aagagatttt taagtgtaaa ggttgataga
    53161 ctaactgaag gctcggtaat tctcttttca aatagtcttt tactgtttta gtttgagctt
    53221 cgtctaataa agcacttaaa acgactcgtt cagcatacgt tcctagatag tagcgttgct
    53281 gctcaggatt taatcttctt tctccccagg ctccttttaa tagcttatct tctaaattag
    53341 tcatagatac cctcgcttct ttataatagt ttctttatta tatcgatttc tacaataaaa
    53401 taccaatttg aaaattttcg gtaaatgtgt taaaaaacaa gaaagaaagt gatttttctt
    53461 gcaaaaaaca aaggaagctt ttcatgagat tgctttttaa gttgattaaa ggcctagttt
    53521 gtggtattat gaacatgtaa aatattaaaa ctcataagga gagtattaca atgtcaatta
    53581 ttactgatgt atacgctcgc gaagtccttg actcacgcgg taacccaaca cttgaagtag
    53641 aagtttatac agaatcaggt gcattcggac gtggtatggt tccttcagga gcttcaactg
    53701 gtgaacatga agccgttgaa cttcgtgatg gtgacaaatc tcgttacctt ggtctaggta
    53761 ctcaaaaagc agttgataac gttaataaca ttatcgctga ggcaatcatc ggttacgatg
    53821 ttcgcgatca acaagctatc gaccgtgcaa tgatcgctct tgacggtact cctaacaaag
    53881 gtaaacttgg tgctaatgct attcttggtg tttctatcgc tgttgctcgt gcagctgctg
    53941 actatcttga agtgccactt tacacttacc ttggcggatt caacactaaa gttcttccaa
    54001 ctcctatgat gaacatcatc aacggtggat cacactcaga tgccccaatt gcattccaag
    54061 agttcatgat catgccagtt ggtgcaccta ctttcaaaga aggtcttcgt tggggtgctg
    54121 aagttttcca cgctcttaag aaaattctta aagaacgtgg acttgttaca gctgtaggtg
    54181 acgaaggtgg atttgctcct aaatttgaag gaactgaaga cggtgtagaa actatcctta
    54241 aagctattga agcagctggt tacgaagctg gtgaaaacgg cattatgatc ggttttgact
    54301 gtgcatcatc agaattctac gacaaagaac gtaaagttta cgactacact aaatttgaag
    54361 gtgaaggcgc tgctgttcgt acatctgcag aacaagttga ttaccttgaa gagttggtta
    54421 acaaataccc aattattact atcgaagatg gtatggatga aaacgactgg gatggttgga
    54481 aagttcttac tgaacgccta ggcaaacgtg ttcaattggt tggtgacgac ttcttcgtta
    54541 caaacactga ataccttgct cgtggtatca aagaaaatgc agctaactca atccttatca
    54601 aagttaacca aatcggtact ttgactgaaa cgtttgaagc tatcgaaatg gctaaagaag
    54661 ctggatatac tgccgttgta tcacaccgtt caggtgaaac tgaagattca acaatcgctg
    54721 acatcgcagt tgcaacaaac gctggccaaa tcaaaacagg ttcattgtca cgtacagacc
    54781 gtattgctaa atacaaccaa ttacttcgta tcgaagatca acttggtgaa gttgctcaat
    54841 acaaaggtat caaatcattc tataacttaa aaaaatagac ggtaagacag aaatcggtca
    54901 ttcgtagaat gcgatttcgt cgtcgcaccc ccgtcaggct gactaggttg gtcacgacaa
    54961 aaggagtgaa catccagtca gctacgacgc aaaagttaaa gattaaagaa tagaaagctt
    55021 gggaaaatcc caagcttttt gctttctaaa tagtaaaaat ttactgtggg ctaatttatc
    55081 ctgagctaat gtattagcga ggtaaagtta ttgaggaagg cttggatttg tactgcctct
    55141 aaaaagttgg acactatatt ttaaatacag gactaagtcc ttttatacca attgtcaagc
    55201 acatcaaggt tttaactgaa aaaatgtttt agacaatagc ctaggtttag ctgttgtctt
    55261 acttgttgtg ctctgattag cataaaaaag tgtacaagaa aaaaaccttg cctagtattt
    55321 ttaagatcaa ggtgttacaa tgatagagca acaacgactt taatgatttt gggtcgaagc
    55381 gtaattgtaa agtttgttat gcgttatgag gtaaagcatt gtctgacaag gcaatgtcta
    55441 gaggcaatcg tatgtggctt ggttgaagct gtttgcgatt gcctttttcg tttctcatag
    55501 aagtctgcga tatgacaagg attggtatga ctagcaaaag caatgtcatg gatacacttg
    55561 aaaagaatct ttgaagcata aggattccca cgtttggtaa tgtgctcttg agctagatag
    55621 ttgccagact cataatgtct aaagtcaatc ccaatgaaag cattaatttg attagcagat
    55681 tgaaaacgac gaatagcacc gagttcgcca ataatacttg ttgcagttgt ttctgcgata
    55741 cttggaatag agcgtagaat cttgtcttct ggtaaaggtt gagccaacgc caccatctta
    55801 tcaaaaatag cttgacgacg ttcagaaagt ctaagtaatt ctttggcata gtagcgaacc
    55861 tcttctatca tcggagaggt tttcgtaaca gtaaaataag actgcttggc taatgagaca
    55921 agtttttcca ctaagtagat cccacgcttg tcagagatac gtttagaggt agattgacgg
    55981 atgatagctg acaatgcttt gtcagctagc tccagtacaa agctattaca tggaaaagcc
    56041 gttaccacat tccagtatta ctcaccagtt ggtgcaaata agatgtgttc cagttcagga
    56101 aaagtgactt gtaagatctt gtgaaggcga ttcttaactc tcgaacaata ttatcctcag
    56161 tcaatttttg atagaagcga ctcaagtcac gtagcagctg ataaacttct tcctgaacgt
    56221 aagttggttt tctaactaga ataaattgag actgagccaa tttttcagtg tctaacttat
    56281 ccgctttacg cacccgtaga ctatctagtt ttctaaagga ttgagttgtg tataagcgta
    56341 gccatttttc tcaaggaagg actgaagccg acgagaatag actcctgttg tgatggtctc
    56401 ccttttgcct tttaaacaat agtatagccg tttttcaaga tgttattaat gattttttcc
    56461 tttattctag aagaataagt ctgatactgt ttcttcttaa taatctcaat gccctaacag
    56521 tccatcagtc gaacggtatt tctcaaatta ctgcagttga ctcttgcgtt cagttccctc
    56581 accttgtgga tgccgtttag aacaatatta gcttgctgaa ttagcttgct gagccttttg
    56641 gtaatgtgaa caaagcatct ttatcactca aggagaagac aggttcttgt ggtaagtgtc
    56701 caacaaggtc acgataaact catcgtaccg tttttggcgg aagtctagaa atgccttatg
    56761 aatgtaagcc tcagaaacgt ctctaaaact aaacaagaaa tacaagaaca aatgcccttg
    56821 attctggtac aaatgctgta tcaggttcag gtattgccta tctgcgataa tgacactctg
    56881 cttttcctta acaatatctt tgaaaggaat gatttcgaca ttgacaggca taaccgttgc
    56941 aatagctggc gggaagtaaa tcgagagtgc attggtcatc aaatccagcg cagcagtgtt
    57001 attggtcaaa agatagacag gtatcggtgg caaatatgtt tttaggagtt cctctaactg
    57061 tatcgtgaag agcagtaaat gataggacgg cagtttcccc acgatgcctt ctgcgctcat
    57121 ccattcctca acgatggttt ttagagtatt gtagaagctc ttgtttcgtt tttgctgtct
    57181 tctgaggtaa tggaacaagt gtatatcagg taacaaaact tgaagattac tgataaatag
    57241 acgtgagaag gaaaccaaaa tccgtttgaa aggaagggag tttaggatat tattgcctag
    57301 tagtggacgc agggatgctt tcaaggtttt tccatttgtt tttgtcatca ccaactcaaa
    57361 caattctttc acttttttag gtgtccattt atccttatgg aaagaattat tggtggtgca
    57421 aaaacataag aaaatataat ccaaatcctc atcagttaaa tcaggatggt accattttcc
    57481 gatgatttcc tgactggtca ttttgatatc tcgatagata gacagttttt tcaagtgttt
    57541 gaatgcatct gtctgaggga tccccaagtt atcatgtcgc cgtttccata taagggatat
    57601 cagaatggca aagtatgaaa attcataagg ggctttactg gcatcattaa gtgtgatggc
    57661 ttgattggag tttataatca gcgaaaccac tttattcatt gatgttttat caaaatcata
    57721 aatggtcata ccaaactgat agtgcaacaa ggcgatcaga aagcggatac ggtattctgg
    57781 tccaacaata tggttttgcc gaacgtttaa acctaccttt ttcaagtatt tccgacaatt
    57841 ggtcctgata cggtaagcgg tggcttggga aatatactct cgtttaatga agtcgtgtag
    57901 gctcagctct cctggttcaa ttaaaaaaca taacatcttt aagaatatcg aggtttgata
    57961 gagtttctta aaataaggca ttttaagttg gtaggtctta taggggatag aaacagtgtc
    58021 gtcacaaatg gttaaggtga gggtgtcttc taaatcctta atcatttcaa agagtaagtt
    58081 gtagacacgt tgttttttga gttcggtttc ctgacacaac tggtctatgg agacttcgga
    58141 aacgtctaac aaaatgttga gcagtgataa tttatcttgt aatttggttt ctagatgaag
    58201 gtgtaacata actgaactcc tttcattttt atagcagaaa ctcgtattta tttaattatc
    58261 acataattaa ataaaacagt caaataattc aatggtgacg cgtgtttaag gagtattgag
    58321 aatgtcagat ataagcaaaa tgcagctgaa tattcttaat tttaggtatg aaaaagcgtc
    58381 gggattgata aaaaatctat tgaattgggt aaatttaagt tgatataata agttgattag
    58441 aaaaattaat aattcattta aattctaatc agctgtaacg ttccggggcg tgttaaactg
    58501 tctgaacata gaaaatacag gtttctacgg tgactaaaat aagctaagga ggattcctta
    58561 aattctgtga taggaacgta aactctctac aagagtagag cacgtcatca gtcagtctgg
    58621 gtgtctactg gctgacaacg tcaaataaga taggcatgaa aaaataaggg ggaatacaga
    58681 atgtttttaa aacaccaaga tgtgaaacaa aaaaattgga gaatgcgtaa ggtcaaaaaa
    58741 gtctttgtta gttcatgtat gcttttaaca gtgggcctcg gagttgccgt actactgcat
    58801 tcagccaatc taatggcgtg atggtcgtaa aggctgcgga agctgaagaa ctgccagaca
    58861 atttaattga ttttaaagga acttgggaag tatctgccga tggctcttct ggtcgcttct
    58921 attcagacgg tgctacaggt caatataagt ttcaccttat tccagcttca gatgttaaaa
    58981 atccgggatg gcatgaacat aataaagtta aagatagcta tgtcaaaata accaaagagt
    59041 ctattgcagc tagatataca aataaaacga aacctccata ttctgtagcg tttaaggtca
    59101 acactaaatc tttaataaaa gatcatgact ataagataac ttttgagcaa ggttcaattg
    59161 cgtcgggaat aacagttgat tatcgtatag gcagtgcttt taataaaact aaagatgatt
    59221 ctttcaacat ttcagatgag agtaaatatg cttctaaggt aacaatagaa ggtgaggaaa
    59281 gaggttttat aaataggaaa ccaggaacta aaacaatatc ttttagagct gtagaaaaag
    59341 gaactaaatc tcttgtattg ttatctaaag ttaatgaaaa aacccaagta gatcttgatg
    59401 tcgagtttaa aaacttcaaa attattgatg ttaccaaccc aagccaatta gataaaggag
    59461 ttgcttacgt tggaaacaaa aatgtagaat tgacattaaa atcagacgat ggaagaacaa
    59521 acttcgaagg tgatgagata agccttttta agcctaatgg agatttgtta aagaaaattg
    59581 aagttaaaga aggacaaaaa aatcctatat caataacttt atctgaagat caagccaaat
    59641 ctttaaaaaa caaagaaaag ttaaaagtaa gcattaaaca aaagcaatca aaaaagactt
    59701 ctaaagactt tttctttgag gtaggaattg atcctaaagt taaagcaaag caacaagaaa
    59761 aactcttaga actagacaaa gtaaaaaaac aaattgaaga ctcaatcaat ggtgatgcat
    59821 ggctaccaga aaaatcggaa ggcgaaaaac cagtacaaaa tactaataaa gaattacagt
    59881 tacaagaact gaacaagaag tatcagatgg ccaaagaggc aattgaaagt gctacaactc
    59941 ttgacgatgt tgaaactcag tttgataaat acacaaaagt tggagataaa gataaatacc
    60001 cggattcttt acgtaaccaa tatactcgag gagataaaga taaagaaata gaaaaagcta
    60061 aaaaatcact gggtgattta agcgataaag tgaatggaaa gattgaagaa gataagtggc
    60121 tatctgacga agttaaaaaa aaacaacagc aagaattaga agcgcgtaaa caaaaagtaa
    60181 acgactctct taaaggatct gatagtttaa aatcattgag agaaacagtg gaaaaagctt
    60241 cttctaaaaa tcagaaaaaa ccagaatctt ttgaagatgt ttatgttcct ggaaatgaag
    60301 aaactgaaaa aacaaaagtt cgtgatatac ttcaaaaaac ttatcaaaaa acagagcaaa
    60361 atattgaaac agatccatgg ttgagtccgg aacagaaaaa agctcaaaaa gaaaacgcta
    60421 aagcaagatt agatgcaggt ttgaaagctg tcgaaactac agaaagctta gataaactta
    60481 aagaagttga gagtgacttc cttgataaag aaaaaaatcc agattcaatt ccaaatcaac
    60541 ataaagctgg aactcctgaa gttgctcgca aaactttctt agataacttt gaaaaagaag
    60601 ccaaaaaaga gattgaatct attgataaag atgatacctt aacggcaaat gctaaacaag
    60661 tagctaaaga taaagtggca caacagctac aagaagctac agctaaagta gagaaagcac
    60721 agtcgtttga tgatttgaag aacattcaag ataagttcaa ttctgaatta ccacacacac
    60781 caggtaagcc gcttaaagat caacaatctg atgctattgc agaattagag aagaagcagc
    60841 aagaaattga aaaagctatt gagggtgata aaacattacc aagagacgaa aaagagaaac
    60901 aaattgctga ctctaaggaa cgcttaaaat ctgacacgca aaaagttaaa gatgctaaaa
    60961 atgctgatgc tattaaaaaa gcatttgaag aagggaaagt ggatattcct caagcacata
    61021 tcccaggtga tttgaacaag gataaagaaa aacttcttgc agagttgaag caaaaagcag
    61081 atgatactga aaaagcgatt gattccgata aaactttgac agcgaaagaa aaagaagagc
    61141 aaaaagcgaa aacaaaagaa gaacttcaaa aagcaacaga agctgttgga gcaattgaca
    61201 atcgtgaaga actagataaa aaagtcccag aacttaagaa agctattgaa gacactcacg
    61261 ttaaaggtaa tcttgaaggt attaagaata aggctattga agatcttaaa aaagctcata
    61321 ctgaaacagt tgctaaaata aatggtgatg atacccttga caaagctact aaagaagctc
    61381 aagtgaaaga agctgacaaa gctttggcag caggtaaaga agctatcact aaagcagatg
    61441 atgctgataa agtaagtaca gctgttacag agcacacacc aaaaattaaa gcagcacata
    61501 aaactggtga tcttaaaaaa gctcaagtag atgctaacac agctcttgac aaagcagctg
    61561 aaaaagaacg tgaagaaatc aataatgata tcacattaac ggcaaaagac aaagaacaac
    61621 aactgaaaga agttgagaca gctcttacta aagctaaaga taacgtgaaa gctgctaaga
    61681 cagcagacgc tatcaatgac gcacgtgata aaggcgtagc aacaattgat gccgttcata
    61741 aagcaggtca agatttaggt gctcgtaagt caggtcaagt cgctaaactt gaagaagcag
    61801 ctaaagcaac gaaagacaag atttcagctg atccaacttt gacaagcaaa gaaaaagaag
    61861 agcaatctaa agctgttaac gctgaactta agaaagcgat agaagctgtt aacgcagctg
    61921 acacagctga caaggttgac gatgctcttg gtaaaggtgt cacagacatc aagaaccaac
    61981 ataagacagg tgaccctatc gaagctcgtc gtggattaca caacaagtca atcgacgaag
    62041 tggcgcaagc aactaaggac gctatcacag cagatacgac tttgactgaa gctgaaaaag
    62101 aaacacaacg tggcaatgtt gataaagaag caactaaagc taaagaagaa cttgctaagg
    62161 ctaaagatgc tgatgcttta gacaaagcgt atggtgacgg tgtaaccagc atcaagaacc
    62221 aacacaagtc aggtaaaggt cttgacgttc gtaaagatga gcacaagaaa gctcttgaag
    62281 ctgttgctaa acgtgtcact gctgaaattg aggctgatcc aaccttaaca ccagaagtga
    62341 gagaacaaca aaaagcagag gttcaaaaag agcttgaact tgcgactgat aagattgctg
    62401 aagctaaaga tgcagatgaa gcagacaaag cttacggtga cggtgtcaca gcgatcgaaa
    62461 atgcccacgt tattggtaaa ggtatcgaag ctcgtaaaga ccttgctaag aaagaccttg
    62521 ctgaagctgc tgctaagaca aaagctctca ttattgaaga caaaacgctt actgatgatc
    62581 aacgtaaaga acagttatta ggtgttgata cagagtatgc taaaggtatc gagaatattg
    62641 atgcagctaa ggatgctgca ggtgttgata aagcatatag tgacggtgtt cgtgacatcc
    62701 tggcacagta caaagaaggt caaaacctta atgatcgtcg taatgctgcc aaagaatttc
    62761 ttcttaaaga agcagacaaa gtgacgaaac taatcaatga tgatccaacc ttgactcatg
    62821 accaaaaagt tgatcaaatc aacaaagttg aacaagctaa gttagacgca atcaagtctg
    62881 ttgatgatgc tcaaacagct gatgctatca atgatgctct tggtaagggt attgaaaaca
    62941 tcaacaacca ataccaacat ggcgatggcg ttgatgttcg taaagcgact gccaaagacg
    63001 atcttgaaaa agaagctgct aaagtgaaag ctcttattgc taaggatcca accttgactc
    63061 aagctgataa agacaagcaa acagcagcgg ttgacgcagc taagaacaca gcaattgcag
    63121 cggttgataa agcgacaaca gcagatggtg ttaaccaaga acttggtaaa ggcatcacag
    63181 ctatcaacaa agcttaccgt ccaggtgaag ctgttaaagc acgtaaagaa gccgctaaag
    63241 ctgatcttga aaaagaagct gctaaagtga aagctcttat tgctaaggat ccgaccttaa
    63301 ctcaagctgc taaagacaaa caaacagcag cggttgacgc agctaagaat acagcaattg
    63361 tagcggttga taaagcgaca acagctgaag gcattaacca agaacttggt aaaggcatca
    63421 cagctatcaa taaagcttac cgtccaggtg aaggtgttaa agcacgtaaa gaagccgcta
    63481 aagctgatct tgaaaaagaa gctgctaaag tgaaagctct tattactaac gacccaacct
    63541 taacaaaagc tgataaagct aaacaaacag aagctgttgc taaagccctt aaagctgcta
    63601 tcgcagcggt tgataaagcg acaacagctg aaggcattaa ccaagaactt ggtaaaggca
    63661 tcacagctat caataaagct taccgtccag gtgaaggtgt taaagcacgt aaagaagccg
    63721 ctaaggctga tcttgaaaga gaagctgcta aggttcgtga agctatcgct aacgacccaa
    63781 ccttaacaaa agctgataaa gctaaacaaa cagaagctgt tgctaaagct cttaaagctg
    63841 ctatcgcagc ggttgataaa gcgacaacag ctgaaggcat taaccaagaa cttggtaaag
    63901 gcatcacagc tatcaacaaa gcttaccgtc caggtgaagg tgttgaagca cataaagaag
    63961 ctgctaaagc taatcttgaa aaagtagcta aagaaactaa agctcttatt tcaggagacc
    64021 gttacttgag cgaaactgaa aaagcagtcc aaaaacaagc tgttgagcaa gctcttgcga
    64081 aagcacttgg tcaagttgag gctgctaaga cagttgaagc tgttaagttg gcagaaaacc
    64141 ttggtactgt agctatccgt tcagcatatg ttgctggttt agctaaagat actgatcaag
    64201 caacagctgc tcttaacgaa gcgaaacaag ctgctattga agctcttaaa caagctgcgg
    64261 cagaaacact tgctaagatt acaactgatg ctaaattgac tgaagctcaa aaagctgaac
    64321 aatcagaaaa tgtatcatta gcgcttaaga cggctattgc gactgttcgt tcagcacaat
    64381 ctattgcgtc tgtgaaagaa gcaatagata aaggtattac tgctatccgt gcagcctatg
    64441 tgcctaataa ggcagtcgca aaatcatcgt cagcgaacca tcttccaaaa tcaggtgatg
    64501 caaactcaat tgttcttgtt ggcttaggag ttatgtctct tcttttaggt atggtgcttt
    64561 atagcaagaa aaaagaaagt aaagactaag aacctggctt tatccaaatt gctttctact
    64621 atattttcaa accaaggtga ttttgaaatc accttggttt tttggatcgt aagggcccaa
    64681 gaacggagtg tattgaaaac atttcaaagt tcaattgaaa aggcaacagt tttctgtaca
    64741 gaatttataa ggcgtttttt gttcaaacga tgactcattt agttatgggt gtttgataat
    64801 taagattact gtgaaggtga tggtagttcc accagtggac ttcctccttg gttttaaggg
    64861 ttaattgttc tagtgaataa aaggtttctt ggtcgcgcag tagggatcaa gcgagcagat
    64921 aaaatgccta ttttaaatca gttcgagcga attttcgtgc tacaagctca aaagaggcta
    64981 ctaaagtatt agaatagttt atctctgagt gaagttcttg ttataagaag atgatgttat
    65041 cgtttgaaac gaccaaaaaa tctcctaact tttactaatt tctacatgaa atctagtc
//
LOCUS       DATWVB010000006        63624 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.006, whole genome shotgun sequence.
ACCESSION   DATWVB010000006 DATWVB010000000
VERSION     DATWVB010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63624
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.006"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..230)
                     /locus_tag="VCX65_000411"
     CDS             complement(<1..230)
                     /locus_tag="VCX65_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP5052898.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLEKIPNSGDGFPLKITINKELTGFKLAITDQS"
     gene            complement(220..1347)
                     /locus_tag="VCX65_000412"
     CDS             complement(220..1347)
                     /locus_tag="VCX65_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP5052899.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            complement(1344..2324)
                     /locus_tag="VCX65_000413"
     CDS             complement(1344..2324)
                     /locus_tag="VCX65_000413"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEP5052900.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAAEVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            complement(2464..3042)
                     /locus_tag="VCX65_000414"
     CDS             complement(2464..3042)
                     /locus_tag="VCX65_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEP5052901.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLSQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFANSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHIAFKYAKSKVARCINTLKKFNDK"
     gene            3130..3801
                     /locus_tag="VCX65_000415"
     CDS             3130..3801
                     /locus_tag="VCX65_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEP5052902.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            3776..4612
                     /locus_tag="VCX65_000416"
     CDS             3776..4612
                     /locus_tag="VCX65_000416"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEP5052903.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWKRVKDAFIGEI
                     DS"
     gene            4609..5514
                     /locus_tag="VCX65_000417"
     CDS             4609..5514
                     /locus_tag="VCX65_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEP5052904.1"
                     /translation="MRFEFVADKRIKVKTLLKSHDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGTLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSYAIHLTDDFDSVIIGLQKKDRGY"
     gene            5518..6513
                     /gene="pta"
                     /locus_tag="VCX65_000418"
     CDS             5518..6513
                     /gene="pta"
                     /locus_tag="VCX65_000418"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEP5052905.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKEAFVDIRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIAKGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFIFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            6640..7395
                     /locus_tag="VCX65_000419"
     CDS             6640..7395
                     /locus_tag="VCX65_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEP5052906.1"
                     /translation="MGNIALVTGASAGFGRAIVEQLIADGIKVIGASRRLEKLKALET
                     SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENW
                     MTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGANIYGASKAFVKQF
                     SLNLRADLAGTHIRVTNIEPGLCDGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIAST
                     VSWVIHQPPHVNVNRIELMPVSQSYGPQPVSRD"
     gene            complement(7589..8278)
                     /locus_tag="VCX65_000420"
     CDS             complement(7589..8278)
                     /locus_tag="VCX65_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEP5052907.1"
                     /translation="MKNAISILALLTSENQLEDMFIRELSHHFSHLFEVTILTSKANI
                     ESNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTRF
                     YQKFDRHFLQYLPLQARLSDANGNIIVDNHAFNGSFLPTTDKEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLDTVQDIKPLLNQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            8701..9429
                     /locus_tag="VCX65_000421"
     CDS             8701..9429
                     /locus_tag="VCX65_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5052908.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQKELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPEM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVANLFGGDEHA"
     gene            9422..10948
                     /locus_tag="VCX65_000422"
     CDS             9422..10948
                     /locus_tag="VCX65_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEP5052909.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
                     "
     gene            11226..12209
                     /gene="guaC"
                     /locus_tag="VCX65_000423"
     CDS             11226..12209
                     /gene="guaC"
                     /locus_tag="VCX65_000423"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEP5052910.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAERLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKACEY
                     EFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     regulatory      12332..12427
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12514..13095
                     /locus_tag="VCX65_000424"
     CDS             12514..13095
                     /locus_tag="VCX65_000424"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEP5052911.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     gene            13095..14378
                     /locus_tag="VCX65_000425"
     CDS             13095..14378
                     /locus_tag="VCX65_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEP5052912.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSGAM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVVGTLVSAMMGLVDTTPVVEASWIH
                     VLTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(14442..15380)
                     /locus_tag="VCX65_000426"
     CDS             complement(14442..15380)
                     /locus_tag="VCX65_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEP5052913.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPLSVHSDLFNLIQIGKAHSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTAKGKQYHHILDRQTGYPIETDMLSLTIMAPSSFYCDIWATRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(15433..15618)
                     /locus_tag="VCX65_000427"
     CDS             complement(15433..15618)
                     /locus_tag="VCX65_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEP5052914.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            15756..16325
                     /locus_tag="VCX65_000428"
     CDS             15756..16325
                     /locus_tag="VCX65_000428"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEP5052915.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPEI"
     gene            16360..17439
                     /gene="prfA"
                     /locus_tag="VCX65_000429"
     CDS             16360..17439
                     /gene="prfA"
                     /locus_tag="VCX65_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEP5052916.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            17439..18278
                     /gene="prmC"
                     /locus_tag="VCX65_000430"
     CDS             17439..18278
                     /gene="prmC"
                     /locus_tag="VCX65_000430"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEP5052917.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLSYVFREIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISGTFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLTKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRVVTDIFGKERMVVVDYG
                     VSS"
     gene            18262..18852
                     /locus_tag="VCX65_000431"
     CDS             18262..18852
                     /locus_tag="VCX65_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEP5052918.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPSHPITTALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            18870..19322
                     /locus_tag="VCX65_000432"
     CDS             18870..19322
                     /locus_tag="VCX65_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP5052919.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALESQA
                     RQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            19312..20568
                     /locus_tag="VCX65_000433"
     CDS             19312..20568
                     /locus_tag="VCX65_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEP5052920.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     HYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIAHLIIKALVN
                     HDQETILEEVRQEVRQLTDAFPLYKK"
     gene            20575..21552
                     /locus_tag="VCX65_000434"
     CDS             20575..21552
                     /locus_tag="VCX65_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEP5052921.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDVLSPEKLADQLFDDNLTARLTFVDQVKDVIPEPIKISDIDHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            21553..22151
                     /locus_tag="VCX65_000435"
                     /pseudo
     CDS             21553..22151
                     /locus_tag="VCX65_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            22161..23879
                     /locus_tag="VCX65_000436"
     CDS             22161..23879
                     /locus_tag="VCX65_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5052922.1"
                     /translation="MKRLRPYLKGYLKESILGPLFKLLEALFELLVPLLIANMIDISI
                     SQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDHLGYASLVSRLTSDSFQIQTGINQFLRLFLRAPIIVCGAMVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KQQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEVPLPLLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSQYSGEISLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPINDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRL
                     FKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGE"
     gene            23882..25609
                     /locus_tag="VCX65_000437"
     CDS             23882..25609
                     /locus_tag="VCX65_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5052923.1"
                     /translation="MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVVIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQLVFNQFILGLLTILCTIIAMAQID
                     WLMLILVLVLIPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEVLRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKAIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRGEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSID
                     IRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            25850..27220
                     /locus_tag="VCX65_000438"
     CDS             25850..27220
                     /locus_tag="VCX65_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEP5052924.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDTKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDMSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(27379..28362)
                     /locus_tag="VCX65_000439"
     CDS             complement(27379..28362)
                     /locus_tag="VCX65_000439"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEP5052925.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
     gene            28553..31039
                     /gene="gyrA"
                     /locus_tag="VCX65_000440"
     CDS             28553..31039
                     /gene="gyrA"
                     /locus_tag="VCX65_000440"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEP5052926.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIAEINTDRENSISKNKDN"
     gene            31059..31808
                     /locus_tag="VCX65_000441"
     CDS             31059..31808
                     /locus_tag="VCX65_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEP5052927.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYNQVST"
     gene            31891..32304
                     /locus_tag="VCX65_000442"
     CDS             31891..32304
                     /locus_tag="VCX65_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEP5052928.1"
                     /translation="MKLNAIHHVAIIVSDYHLSKDFYVNKLGFEIIRENYRSDKHDYK
                     LDLSCGRIELEIFGKVTSDPNYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGIPVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
     gene            32918..33352
                     /locus_tag="VCX65_000443"
     CDS             32918..33352
                     /locus_tag="VCX65_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052929.1"
                     /translation="MTKKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKDSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEEKWQDTKDAVEVYGGIATE
                     TVEESLGQVKEKVEGIGEATSQTIQSKMEKLTSDKTDADDEK"
     gene            complement(33402..34313)
                     /locus_tag="VCX65_000444"
     CDS             complement(33402..34313)
                     /locus_tag="VCX65_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEP5052930.1"
                     /translation="MKTVRIFYNPNSGKKENQLARQVKDYFCQHGFSEDSVEVITPKD
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIMQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGEFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAISIIVPTED"
     gene            complement(34430..35080)
                     /locus_tag="VCX65_000445"
     CDS             complement(34430..35080)
                     /locus_tag="VCX65_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEP5052931.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(35077..35517)
                     /locus_tag="VCX65_000446"
     CDS             complement(35077..35517)
                     /locus_tag="VCX65_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEP5052932.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLLQEVIQ"
     gene            35736..36584
                     /gene="ylqF"
                     /locus_tag="VCX65_000447"
     CDS             35736..36584
                     /gene="ylqF"
                     /locus_tag="VCX65_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEP5052933.1"
                     /translation="MATIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKTHY
                     PSRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GDMDVD"
     gene            36574..37365
                     /locus_tag="VCX65_000448"
     CDS             36574..37365
                     /locus_tag="VCX65_000448"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEP5052934.1"
                     /translation="MSTSIKAIKESLEAVTSLSDPLFQELATDARLGVQKALKSRQKA
                     IQADLAEEERLEAMLSYEKALYKEGYQAIAGIDEVGRGPLAGPVVAACVILPQHCKIK
                     GLNDSKKIPKSKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     GQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            37430..38266
                     /gene="dprA"
                     /locus_tag="VCX65_000449"
     CDS             37430..38266
                     /gene="dprA"
                     /locus_tag="VCX65_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEP5052935.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            38373..40502
                     /gene="topA"
                     /locus_tag="VCX65_000450"
     CDS             38373..40502
                     /gene="topA"
                     /locus_tag="VCX65_000450"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEP5052936.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGSLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDG
                     LFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFIINRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVIFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMAEGETVKKISTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEQWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            complement(40577..41461)
                     /locus_tag="VCX65_000451"
                     /pseudo
     CDS             complement(40577..41461)
                     /locus_tag="VCX65_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354842.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            41474..42019
                     /locus_tag="VCX65_000452"
                     /pseudo
     CDS             41474..42019
                     /locus_tag="VCX65_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631865.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            42034..43026
                     /locus_tag="VCX65_000453"
     CDS             42034..43026
                     /locus_tag="VCX65_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HEP5052937.1"
                     /translation="MKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEG
                     FDGIANAQIGPLDDAIYPLLREMGIKQIAQRSAGVDMYNLDLATENDIIITNVPSYSP
                     ESIAEFTVTIALNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVAIIGTGRIGLAT
                     AKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDADFVSLHMPPTAENTHLFNA
                     DLFKSFKKGAILMNMARGALIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQE
                     ITDSLFKALINHPKVIYTPHAAYYTDEAVKNLVEGALNATVEIIKTGTTTTRVN"
     gene            43131..43796
                     /locus_tag="VCX65_000454"
     CDS             43131..43796
                     /locus_tag="VCX65_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HEP5052938.1"
                     /translation="MTYIALIGDIIQSKQLTDRSKVQKTLAAYLDDLNKTFAPYIISK
                     LSLTLGDEFQGLFQVDTPIFHLIDLINHHMDIPIRFGVGVGSILTDINPDISIGADGP
                     AYWHAREAIRYIHQKNDYGNTTLAFRTGHHNQDDVLNSLLAAGDAIKANWRASQWEIF
                     DTLLDLGIYEEYFDQQRLGKQLSLSSSALSKRLKSSHVKIYLRTRQSALNCLKQIKEE
                     TDD"
     gene            43789..44505
                     /locus_tag="VCX65_000455"
     CDS             43789..44505
                     /locus_tag="VCX65_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEP5052939.1"
                     /translation="MINGVSHYLAQTPTLTLFLICHVLSDYQLQSQQVADLKEKHLTY
                     LGYHLIGVSIPLICLTLIIPQAWLMSLLVMISHALIDWLKPKMANSLKWKREWIFLLD
                     QCLHIAISSFAGLRLAGVTLPNWLPISILMTVLFILLITKPTNIVFKLFFSKYQPDQG
                     EKMDTIIGAGATIGILERIVIGVCMFMGQFASIGLVFTAKSIARYNKISESPAFAEYY
                     LIGSLFSILSVFIAAWICFF"
     gene            44651..45997
                     /gene="trmFO"
                     /locus_tag="VCX65_000456"
     CDS             44651..45997
                     /gene="trmFO"
                     /locus_tag="VCX65_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEP5052940.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAKSVTAELENHPLIEVIRDEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHDALTNAEEAPL
                     NAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRNNPNLFFAGQMTGVEGYVESAASGLVAGTNAARLFKREEALVFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            46150..47556
                     /locus_tag="VCX65_000457"
     CDS             46150..47556
                     /locus_tag="VCX65_000457"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HEP5052941.1"
                     /translation="MIQFGGFSMQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTIL
                     DKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHY
                     ADDIVDKFISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVH
                     TLNYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSG
                     ISQMTYLAAVEAGADRIDTALSPFSEGTSQPATESMYLALKEAGYDITLDETLLEQAA
                     NHLRQVRQKYLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLA
                     EVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPV
                     NEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFL
                     TTKYQTDDVIKVTAFIKA"
     gene            47599..47913
                     /locus_tag="VCX65_000458"
     CDS             47599..47913
                     /locus_tag="VCX65_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052942.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            47913..48263
                     /locus_tag="VCX65_000459"
     CDS             47913..48263
                     /locus_tag="VCX65_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="HEP5052943.1"
                     /translation="MKRYEVTVNGQVYEVSLLELADGETVQVSRPAAPATEKEMNANA
                     AGGGLQVKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            48273..49403
                     /locus_tag="VCX65_000460"
     CDS             48273..49403
                     /locus_tag="VCX65_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEP5052944.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVENLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKVMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(49604..50488)
                     /gene="citG"
                     /locus_tag="VCX65_000461"
     CDS             complement(49604..50488)
                     /gene="citG"
                     /locus_tag="VCX65_000461"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEP5052945.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFM
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGCFSKEDTLAICRLVKPMTAHLIQTDLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(50481..51176)
                     /locus_tag="VCX65_000462"
     CDS             complement(50481..51176)
                     /locus_tag="VCX65_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP5052946.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKTTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(51334..52737)
                     /locus_tag="VCX65_000463"
     CDS             complement(51334..52737)
                     /locus_tag="VCX65_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEP5052947.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
     gene            53117..53440
                     /locus_tag="VCX65_000464"
     CDS             53117..53440
                     /locus_tag="VCX65_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052948.1"
                     /translation="MQFLQKWFKHSKKEKLKESSPLSTEIEPSENWEKIPAYIPADKS
                     DYKKVTLITSAIAAGDRPNSQFKVKRILKRNPEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
     gene            53497..53892
                     /locus_tag="VCX65_000465"
     CDS             53497..53892
                     /locus_tag="VCX65_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEP5052949.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVPVPTEA
                     SPQVEEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VASSAGTITAIHVGPGQVVNPGDGLITIG"
     gene            53937..55058
                     /locus_tag="VCX65_000466"
     CDS             53937..55058
                     /locus_tag="VCX65_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEP5052950.1"
                     /translation="MDTLIAGITSITIPQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFEALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQMTKILFPIIITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            55246..55554
                     /gene="citD"
                     /locus_tag="VCX65_000467"
     CDS             55246..55554
                     /gene="citD"
                     /locus_tag="VCX65_000467"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEP5052951.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEKTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGVDQYDWKEIDSWNV
                     "
     gene            55542..56429
                     /gene="citE"
                     /locus_tag="VCX65_000468"
     CDS             55542..56429
                     /gene="citE"
                     /locus_tag="VCX65_000468"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEP5052952.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDIV
                     DVEAVIERVERENSIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEIDHSKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AECVIALATAAGVLSEEDI"
     gene            56432..57964
                     /gene="citF"
                     /locus_tag="VCX65_000469"
     CDS             56432..57964
                     /gene="citF"
                     /locus_tag="VCX65_000469"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEP5052953.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELANIKQYDESSRRIKPVKPG
                     DSKLLGSVREAIEKTGLTDGMTISFHHHFREGDFIMNMVLEEIAKMGIKNLSIAPSSI
                     ANVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLMENPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDAYGNVNGTKGKATCGSLGYAMIDAKYADQVVILTDNLVPYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITNSPYFKEGFSF
                     QTGTGGASLAVTRFMREAMIKENIKASFALGGITNAMVELLEEGLVEKILDVQDFDHP
                     SAVSLGKHADHYEIDANMYASPLSKGAVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEVGIAINP
                     NRQDLVDHFKSLNVPQFSIEELKEKAYAIVGTPERIQYGDKVVALIEYRDGSLMDVVY
                     NV"
     gene            57957..58535
                     /gene="citX"
                     /locus_tag="VCX65_000470"
     CDS             57957..58535
                     /gene="citX"
                     /locus_tag="VCX65_000470"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEP5052954.1"
                     /translation="MCKDTYFSGEAIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEVFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG"
     gene            58550..59944
                     /locus_tag="VCX65_000471"
     CDS             58550..59944
                     /locus_tag="VCX65_000471"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEP5052955.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIRKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFV
                     QKSIENGIDIVRIFDALNDPRNLQTAVSATKKFGGHAQVAISYTTSPVHTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YREIGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLADKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEGIKEKII
                     GDEAVIACRPADLIEPQMIYLRDEIAQYARSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(60054..61106)
                     /gene="citC"
                     /locus_tag="VCX65_000472"
     CDS             complement(60054..61106)
                     /gene="citC"
                     /locus_tag="VCX65_000472"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEP5052956.1"
                     /translation="MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSAYQGGGFLNRIVSHLIDEEYALGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDQSLVPFSVRKMLIQEGLKHLDNIIFHETGPYLISQ
                     ATFPAYFQTEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDSDWDLLAKLLPKTSLDYFCSLEA
                     QPIIKKIQATSSVKHY"
     gene            complement(61195..61677)
                     /locus_tag="VCX65_000473"
     CDS             complement(61195..61677)
                     /locus_tag="VCX65_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEP5052957.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTIDDVINLPVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
     gene            complement(62376..63446)
                     /gene="xerS"
                     /locus_tag="VCX65_000474"
     CDS             complement(62376..63446)
                     /gene="xerS"
                     /locus_tag="VCX65_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEP5052958.1"
                     /translation="MRRELLLEKIETYKAVMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
BASE COUNT        19845 a        11507 c        12938 g        19334 t
ORIGIN      
        1 gattgatcgg tgatagctaa tttaaaacct gtgagttctt tattaatagt gatttttaaa
       61 gggaaaccat cccctgaatt aggtattttt tcgagtaaac gtattaattg gtagtgccct
      121 actttagttt gactaaatgt agtatctctt agggtatatt ttttaatgtt tggactgatt
      181 gtataaaggt atttacagtc tttaagctta atttcttttt caaaagccat ctgttcctcc
      241 taaaatattt tttaatgttt gagctaattg attaacatct tcaatgctat tttgatctga
      301 aaaactgata cgaattgatt cttttaaacg agaagagtca tccccatagt acgcagctaa
      361 aacatgactt ggattaacag ctccagcagt acaagcagaa ccagttgata ctgcaatgcc
      421 tgctaagtca agttgtgtta gtaaaatagt attttggtag cctaaaaatc caatattgag
      481 aacatgagga agataatgag taccttgatt aatatagtag ggtagtcctt ctaggaggct
      541 aatcaagtga tgacgtaaac tgataatgtg atcagttgat tggtcaagac aagtcatagc
      601 atcagtcaaa gcttgtgcca taccaataat acctaacata ttttcagtac ttgcgcgtcg
      661 ctttccttct tgatcacccc cgtgaagaag agggtcgatt ggttgtccgt tactgtataa
      721 aaagccgcat cctttaggac catgaaattt gtgagcagaa gcagataaaa agtcaatccc
      781 aagttcgcta ggaataatct tgagtttgcc aacagcttga acggcatcaa catgaaaagc
      841 agcttgatgg tctttgagca gattcccaat gtccttaata ggtaacaggt cacctgtttc
      901 gttattggca tacattatgc ttaccaaaat ggtgtcatct ctcaaggctt gttttaagtc
      961 agataaattt atttgtccat tttgacaagg caaataagtg acctcaaaac caaatcgctc
     1021 ttcgagatag gccatggtat gaagcacaga gtggtgctca atagtagttg tgatgagatg
     1081 tttgcccttt gcttgatgag ctaaagcata gccttttatg gccatattat tgctttcagt
     1141 tccaccggac gttactataa tttgctgttc acttgccccc aagtttctag cgatagcttg
     1201 tcggcattca cgaaggattt tattggctcg gcgcccgtag aaatgaatac tagaggggtt
     1261 accaaagtta tcttgcatag ctgctgtcat cgccctaatc acattaggac taagtggtgt
     1321 ggtggcggcg ttatcaaagt aagtcatgcg ttatttttgc ctttaggttg ataagaaaaa
     1381 agtggactta agggtcttct ttcatggata cgaataatag cttctgcgat taaatcactg
     1441 gcgctaagat aagtaacgtt ttctggcaca cgatttttag ttttaacaga atctgtaacg
     1501 ataatttctt tgattggagc tgtttctaat acctcagcag ctccaccagc aaataagcca
     1561 tggctagcga ccgcgtaagt atcagtagcg cctgagcgtt caagaatttt agcagcttct
     1621 gcaaaggttt tcccagtatt taaaatatca tcaattaaaa tggctttttt accagaaaca
     1681 tcaccaataa tataaccttg ttcacgttca gaatcatctt gtgcatagtc gataatagca
     1741 atcggggaat caagatattc agccaagctt ctagcacgtt taattccaga atttttaggg
     1801 ctaacgacaa caacatcaga acctgataag cctaatttac tgtaacgttc tgcaaaaaga
     1861 gggactgtaa agaggttatc cactggaata tcaaaaaaac cttgtacctg aacagcatgt
     1921 aagtcaagcg tcactacacg atcaatacca gctttagtca gcatattagc tactagttta
     1981 gcagtaatcg gttcgcgggg cttagcgaca cggtcttgac gagagtaacc aaagtatggc
     2041 aatacaatat tgacggtatt agcacttgca cgtttacaag catcaatcat gatgagtaat
     2101 tcccaaagat tatcattgac aggaaaacta gtggattgaa taatatagat atcatctcca
     2161 cgcactgttt cttcaatatt gatcataatt tctccatcgg aaaattgacg tgaagacatt
     2221 tttccaagag ggattccagc agctttagca attttttcag caattggaag atttgatgtg
     2281 agtgagaaca gtttgatttg cttgtcagca tatcgttcag tcatgataga tttagctcct
     2341 taacttcaat aaaattgggt aaactgtttt attaatgagt cacattaccc aaaagtgttt
     2401 aattgacatc cctattttaa cagaaaaaca gaaaaatttc agtttttctg tcgcttttag
     2461 ccattattta tcgttgaact tttttaaggt gttaatacac cgagctactt tgcttttagc
     2521 atatttgaaa gcaatgtgat gttcagataa aaaagaatca aaatcaatct ttccttgaag
     2581 agcgtcactt acttctaatt ctaattcata gtctttggta ttggcatata ggttatagtc
     2641 taaggccaat ttacctatcg gtatcactgt ctcgcgacga acggtagtta aattgccaaa
     2701 agttaccagt gcagatggtt tgataccttt tgaaataata atatcaagag cagttgattc
     2761 aggaagattc ccatgtttaa tcatatcttt tgcttgttca agaaaaagag ggacattgta
     2821 ctcacgattc cccacttttt ctggcacttt taaggttaat tcggcgctat ttgcaaatgt
     2881 tcgaatacgt aatgacattt tgttagcttt taaatcaaat gcttttgtat caatatagta
     2941 attagtttgt gtaacaggcg tcacatgttt catttgagat aaaagacggt tatactcatt
     3001 ttttgtaagt agagttttat attcgatttc taggttagtc atgggaaatt ccttttaatt
     3061 tgtgctataa taaattgtta tttcaatttt atattattat cctggctttg acaagaaagg
     3121 agacaataga tgaccttaga ttgggaagaa tttttagatc cttatatcca aacagttggt
     3181 gaattaaaaa taaaactacg gggtattcgc aagcaatatc gtaagcaaaa tcgttattct
     3241 ccgattgaat ttgttacggg acgtgttaag tcaattgaaa gtattaaaga aaaaatgatt
     3301 ttacgtggtg ttattgaaga aaatatagca caagatattc aagatattgc tggactacgt
     3361 attatggttc agtttgtcga tgatgtggaa gaagtcttag ctctattgcg tcaacgacaa
     3421 gacatgacaa ttgtttatga acgagattat attcgcaata tgaagtccag tggctacagg
     3481 tcttatcatg ttgtggttga gtaccctgtt gatactattg aaggtcaaaa aaaggtctta
     3541 gcggagattc agattcgtac tttggcaatg aacttttggg cgaccattga gcattcttta
     3601 aattataaat atggtggaga cttcccagaa gaaattaaaa agcgtcttga agtgactgct
     3661 aaaattgctt tagaattaga cgaagaaatg cgtaagattc gagaagatat tcgggaggct
     3721 caattattgt ttgaccccgt gacacgaaat ttaagtgatg gtgtaggaaa tagtgatgac
     3781 acagatgaat tatacaggta aggtaaagcg agttgctatt attgcaaatg gtaagtacca
     3841 aagtaaacgc gtcgcctcca aacttttctc cgtatttaaa gatgatcctg atttctatct
     3901 ttcaaagaaa aatccggata ttgtgatttc tattggcgga gatgggatgc tcttatctgc
     3961 ctttcacatg tatgaaaaag aattagataa ggtacgtttt gtaggaatcc acaccggtca
     4021 tcttggcttt tataccgatt atagggattt tgaagttgat aaattgattg ataatttaag
     4081 aaaagacaag ggagaacaaa tctcttatcc tattttaaaa gttgctatta ctttagatga
     4141 tggtcgtgtg gttaaagcgc gtgctttgaa tgaagcgacg gttaagcgta ttgaaaaaac
     4201 gatggtagca gatgttatta ttaaccatgt caaatttgaa agcttccgag gtgatgggat
     4261 ttcagtatcg accccgacag ggagcacagc ctacaataaa tctttaggtg gtgctgtctt
     4321 gcatccgacg attgaagcgc tgcaattgac ggaaatttcc agtcttaata accgtgtctt
     4381 tagaaccttg ggctcatcaa tcattattcc caaaaaagat aagattgagt tagtgccaaa
     4441 acgattagga atttatacca tttccattga taataaaacc tatcagttaa aaaatgtgac
     4501 gaaggtggag tattttatcg acgatgagaa aattcatttt gtttcctctc cgagtcatac
     4561 gagcttttgg aaaagggtca aggatgcctt tattggagag attgactcat gagatttgaa
     4621 tttgtagcag acaaacgaat aaaagtaaaa acccttttaa aaagtcatga tgtctctaaa
     4681 ggactattgg ctaaaatcaa atataagggc ggtaatatat tagtgaatgg tattgaacaa
     4741 aatgccattt atttattgca agtgggagat gttgtcacca ttgacattcc aaacgaagag
     4801 ccctttgaaa agcttgaagc catccctttt gatttggata ttgttcacga ggatgatcat
     4861 tttttggtga ttaataaacc cattggcttt gccagtattc caagtgccat ccactccaat
     4921 accattgcta actttatcaa ggcatattat gtggacaatc attacctaga ccaacaagtg
     4981 catatcgtga ctcgtttaga cagagatacg agtggcttga tgttatttgc taagcatggt
     5041 tatgctcatg caaggttgga caagcaactc caaactcgct caatagagaa acgttatttt
     5101 gctctggttt ctggaaatgg gacgttgcca gatgaaggag atattattgc tccaattggg
     5161 cgttcaaaag atagtattat taccagggca gttgacccta tgggcaaata tgccaagact
     5221 agctataagg ttgtggcgcg ctattcagaa aatgtgcatt tagtggatat caaattgcat
     5281 acaggacgta cccatcaaat cagagttcat tttgcccata ttggttttcc acttttaggg
     5341 gatgaccttt acggaggtcg tttggactta ggaataacaa ggcaagcttt acattgtcat
     5401 tatttgaatt tcaaagatcc atttacagaa agtgattgta gctatgcaat acacttgaca
     5461 gatgactttg atagcgttat cataggttta cagaaaaaag atagaggtta ttaaagaatg
     5521 agtattcgta gtttattcgg tggtttaaga gaaaaaattc ttggtaaaaa catgaagatt
     5581 gttttcccag aaggtaatga tgagcgcgtc gtccgtgcag ctgctcgttt gaaatttgaa
     5641 ggactcttag aaccgattat ccttggacag tcagaagagg tacgcaacct tttgacaaaa
     5701 ttaggcttcg ctgatcaaga ctatactatc attaatccaa atgaatatgc ggattttgac
     5761 aaaatgaaag aagcttttgt tgacatccgt aaaggaaaag caacgcttga agatgctgat
     5821 aaaatgcttc gtgatgtgaa ttactttggt gttatgttgg ttaaaatggg attagcagat
     5881 ggaatggtat ctggtgctat tcattcaaca gctgatactg ttcgtccagc ccttcaaatc
     5941 attaaaacca aaccaggtat ttcaagaact tcaggtgttt tcttgatgaa tcgcgaaaat
     6001 acgagtgagc gttacgtgtt tgctgattgt gctatcaata ttgacccaac agcacaagaa
     6061 ttggcagaaa tcgctgttaa cacagctgaa acagctaaaa tctttgatat tgatcctaaa
     6121 attgctatgt taagcttctc aacaaaaggt tctggtaaag cgcctcaagt tgataaggta
     6181 agagaagcaa cagaaattgc taaagggttg aaccctgatt tggcacttga tggtgagttg
     6241 caatttgatg cagcctttgt tcctgaaacg gcagctatca aagcaccaga ttcagcggtt
     6301 gctggccaag ccaatacttt tattttccct gacttacaat ctggaaatat tggttacaaa
     6361 attgcacaac gtttaggaat gtttgatgct attggaccaa tcttacaagg attgaacaaa
     6421 cctgttaatg atttatctcg tggctcaagc gctgaagata tttacaaatt agctattatt
     6481 acagcagcac aagctatcga aagccaaggg taacttaaga ccccttgata taggattcta
     6541 accgctaagt gatgtgttag aagttatcct aagactaatt gacattatta aaaacgagtt
     6601 ggccagacca tctcgttttt tttgaaggtg aggaaatgta tgggaaatat tgccttagta
     6661 acaggggctt cagccggttt tggcagagcc attgtcgaac aattaattgc agatgggata
     6721 aaggttattg gtgcttctcg tcgtcttgag aaactcaagg ccttagaaac gagctttggg
     6781 tcggacaact tttacccttt gcagatggat gtcacagata ccaaagcgat tgatgatgct
     6841 ttgacaagtc taccaaatca gtggcaagat attactattt tagtgaataa tgcaggcttg
     6901 gcattgggac ttgataaggc ttatgaagcc gattttgaga attggatgac gatgattaac
     6961 actaatattg ttgggttgat ttatctcaca cgtcaattat taccacatat ggtctccaaa
     7021 gatgatggta ttattattaa tttagggtca accgcaggga caattcccta tccgggagct
     7081 aatatttatg gggctagcaa ggcttttgtt aagcagttct cactcaattt acgagctgat
     7141 ttagcaggta cccatatacg tgtgaccaat attgaacccg gtctatgtga cgggacagaa
     7201 ttttcaaagg ttcgctttaa tggtgatgag gcacgggtga aggccattta tcaaggagca
     7261 catgccattc aacctcaaga tattgcgtcg actgtatcat gggtgattca tcagccccct
     7321 catgttaatg ttaatcgtat tgagctgatg ccagtgtcgc aaagttatgg accgcaacca
     7381 gttagtcgtg actagcaagg gatgagtcca taagaataat aatctttaga aaaatggttt
     7441 actggtatgg attattcttt ataagtgaga cttaccgatt tagtcatcaa aaaaagcaat
     7501 caagaagaag gttttgaggt cttcaagcgt tcatgattgc ttcttgtgcg ttgatgattt
     7561 aggctgaact ccctatttaa aatcaagttt agtgatctaa aatggaaggg cctgatgtga
     7621 catcggacca gccaacaatg gcttgtccag tttcttctaa atactggttt aataacggtt
     7681 taatgtcttg aacggtatcc aaaactccca ccagctgacc ttgaggattt ttaagagctt
     7741 gataatgctg catgtaaata tgatccaatg aacccgaagg aagtaggaag gttttacaag
     7801 ggttatctga taaacgcaat tcagcaagaa tccaatcttc tatttcttta tcagtagttg
     7861 gcaaaaaact tccattaaaa gcatgattat cgactatgat gtttccattt gcatcagata
     7921 accttgcttg caaaggaagg tactgtaaaa aatgtctatc aaatttttgg taaaatctag
     7981 tgaggtattg gcttaacgat aagactgctg ttgcttgatc aaagacactt tctgtcacta
     8041 aaaatccctg accatgttga gaggttttga aatagagtgt aggcaagtca atgtcatgct
     8101 catggaaact gaaaattcct tggaaagtcg acaattgatt tgactcaatg ttggctttgc
     8161 tagtgagaat agtcacctca aaaaggtgtg agaagtggtg ggaaagctct ctaataaaca
     8221 tatcttcaag ttggttttca gatgttaaga gcgctaaaat ggaaatggca tttttcataa
     8281 ttgtatgata gccgtatttt ctagaaaaga caactaatct gcttatctat cataggcaag
     8341 tctaggattt ttgataaggt aattttggag agataggctg acaaagtgac ctgtttttct
     8401 ataaggggta aggagaaata gtctcattat ttgacttata gtgggaaact ttttataatg
     8461 gtcaacaaca aacgacaaga aaataatgag agaaaaagtt tttgagaatt ggtagtttct
     8521 accttactga ggatacctaa gagtcccttt aattagtaga tgcgtttgtc taaaaatggt
     8581 agggcatgca gtgattcctt gtagttactc agaacgtttt gagaaaaaat gacagagaga
     8641 caggttgaat gaactcatca gcttttatgc tgttacttta accaatgaat tggagaaata
     8701 atgatacgtt ttaataatgt ttctaaaact tttggtcaga caaaggtttt gcaagagcag
     8761 acctttcaaa ttaatgaccg tgaatttttt gtgctggttg gtcccagcgg atcggggaaa
     8821 accacacttt taaaaatgat taactgcctt attgaaccaa gctctggaga tattttactg
     8881 aataacgtcc cacagaaaga gttagattta cgtgagatga ggctatctat tggatacgtg
     8941 ttgcagcaaa ttgctctttt ccccaatctc acagtagctg aaaatattgc gattatccct
     9001 gagatgaagc aatggtcagc tgaagaaatt agacaaaaaa ctgaagaatt attggataag
     9061 gtgggcctac ctgctaaaga ttatcttgat cgttacccaa gtgatttatc gggaggtgaa
     9121 cagcaacgta ttggtattgt acgtgctatc atttctcatc ctaaaattct attgatggat
     9181 gaaccatttt cagccttaga tcctatttca cgtaaacaat tgcaagagtt aatgttgagt
     9241 cttcacaagg aatttgacat gacgattgta tttgtgacac atgatattga tgaggccatt
     9301 aaattaggag accgcgtagc tattttaaat gagggagaaa ttgtgcaact ggatcgccca
     9361 gaaatgatta agacccaccc tgctaatgct tttgtggcca atttatttgg aggtgatgag
     9421 catgcctagt ttgtttgtaa ctttccaaaa ccgttttaat gaatggctgg cggctctggg
     9481 ggaacacctg caaatttccc ttttatctct tatgatcgcc ttgctaatag gtgtgccttt
     9541 agcagccctt ctcagtcgca gcaaacgttg gtcagacatt atgttacagg taacaggtgt
     9601 ttttcaaacc attccctcac tggctttgct tggtcttttc atccctttaa tgggaattgg
     9661 aacgttgcct gcagtgacag ctttagttat ctatgcgatt tttccgattt tacaaaacac
     9721 catcacagga ttaaatggta ttgacccaag tctcgtggaa gcaggaatag cttttggaat
     9781 gaccaaatgg gagcggttaa aaacgtttga gattccaatt gcaatgcctg ttattatgtc
     9841 aggtgtgcgg acgtcagcag tcatgattat cggcacagct actttagctt ccttgatagg
     9901 agccggtgga cttggctctt tcatcttatt ggggattgat cgtaataatg ctaacctgat
     9961 tctgataggg gctatttctt cagctctgct agctattatt ttcaatagtt tgttacagta
    10021 ccttgagaaa gcttccttgc gacggattat gattagtttt ggaatcacct tacttgcatt
    10081 gctagcatcg tatactccta tggcgcttag tcagttttca aaaggaaaag atacagtggt
    10141 tattgccggt aaattgggag cagagcccga tattctgatt aatctctata aggaattaat
    10201 tgaagatcaa tcagatataa gtgttgagtt gaaatctaat tttgggaaaa ctagcttctt
    10261 atatgaagcc cttaaatctg gagatattga tatctatcct gaatttacag gaaccataac
    10321 atcaagtctt ttacgcgaca aaccaccttt gtctaatgac cctaagcagg tctatgagga
    10381 tgctaaaaaa ggcattgcta agcaagataa actgaccctt cttaagccat ttgcttacca
    10441 aaatacgtat gctgttgcta tgccagaaaa attggctaag gaatatcaga ttgaaaccat
    10501 ttctgattta aaagcgcatg ctgatacttt aaaggctggt tttactctgg aatttaagga
    10561 cagagcagat ggctataagg gaatgcaatc tcaatatgga ttacagctat ctgtggcgac
    10621 gatggagcca gctcttcgtt atcaagcaat tcaatcagga gatatccaag taacagatgc
    10681 ttactctacg gatgctgaaa tcacgaaata ccatttgaaa gttttaaaag atgataaaca
    10741 gttgtttcca ccttatcagg gagctccttt gatgaaaact tccttattaa caaaacatcc
    10801 agaattaaaa ggcattctta atcaattagc gggaaaaatt actgaaaaag agatgcagga
    10861 catgaactac gaggtatctg ttaaaggagc agatgctaat aaggtcgctc gagattatct
    10921 gttgaaaaca ggcttaatcc agaaataaac agaaatgttg gtccatagga ctggcatttt
    10981 ttcgtctctt aagttcaaga agtaacaatt cataaataca aaaaccgaac atttaaatta
    11041 aaaatagtat ttaaatttga caaaatataa acaaataagt aatctataaa atgaaaggta
    11101 agtttttacc taaatatacc tctaatcatc agaggtcata ggaagattat tttgtataga
    11161 ggacttagag aagaaggtga gaactgactt gtttttctta atctatgtta aaagaggaga
    11221 aacttatgtt taatgacatc cctgtatttg attatgaaga tattcaactg attcctaaca
    11281 agtgcattat tactagtcgt tcacaagcag atacaagtgt gacactcgga aaataccagt
    11341 tcaagctacc agttatccca gcaaatatgc aaaccattat tgatgaaaca attgctgagc
    11401 ggttggcaaa agagggttat ttttatatta tgcatcgttt tgatgaagat agccgcaaac
    11461 cttttatcaa acgcatgcat gaacaaggct tgattgcatc aatctctgtt ggggttaaag
    11521 cttgtgaata tgaatttgtg acctctttga aagaggatgc tcctgagttt atcaccattg
    11581 atattgctca tggtcatgct aacagtgtta ttgatatgat taagcatatc aagactgaat
    11641 taccagaaac atttgtcatt gctggaaatg ttggtacgcc agaagctgta cgagaactcg
    11701 aaaatgcagg tgctgatgct actaaagtag gcatcggtcc aggcaaagta tgtatcacta
    11761 aagttaaaac cggtttcggt acaggtggtt ggcagctagc agcactgcgc tggtgcgcaa
    11821 aggcagctcg taaacctatc attgctgatg gtgggattcg cacacatggt gatattgcta
    11881 aatccatccg ctttggagct agtatggtca tgattggatc gctttttgca ggacatattg
    11941 aaagtcctgg aaaaacggta gaagtggatg gtgaaacgtt taaagaatat tatggctcgg
    12001 cgtcagaata tcaaaaaggc gagcataaaa atgtagaagg caaaaaaatc ttattgccta
    12061 caaaaggtca cttatcagat accctgaccg aaatgcaaca ggatttgcaa tcgtccattt
    12121 cttacgcggg tggtaaagat ttagacagtt tgcgtcatgt tgattatgtt attgtcaaaa
    12181 attccatttg gaatggtgat tccatttaaa tgatatggag ttagctagga ccagtaaaga
    12241 attttttagc ttaatgctgg agatgctttt atcatatctc tgtaggtatt gaaaaaaata
    12301 agaaacatgg taaaatagta aattatcata atgaattcaa taatgacata cttatttatg
    12361 ctgtgaattg gcgcagcgtc tctacaagac accttaatgt ctaacaataa gtaagctttt
    12421 aggcttgctt ggtttttaac cttgcaaagt gagaaactct tatagtttct cactttgcgg
    12481 caggcttttt ctatttgaat caaaaggaga tttatgcagt tacttgaaga acgcatctta
    12541 acagatggca atattctagg agagaatatt ctaaaggtag ataatttttt aactcatcaa
    12601 gttgattacc ggttgatgaa agcaattggt aaagtgtttg ctcaaaaata tgctgaggct
    12661 ggcattacaa aagtggttac aatcgaagct tcaggtattg caccagccgt atacgctgca
    12721 gaagcaatgg atgttcctat gatttttgcg aaaaaacata aaaacattac catgacagaa
    12781 ggcattttga cagcagaagt ttattctttc actaaacaag tgacaagcac ggtgtctatc
    12841 gctggtaaat tcctatctaa agaagacaag gttttgatta ttgatgactt tttagctaat
    12901 ggtcaggcag ccaaaggctt gatcgagatt attggtcaag caggggcaca agtcgtcggc
    12961 gttggtattg tgattgagaa atctttccaa gatggtcgtc gattgattga agatatgggc
    13021 attgaagtga cctcattagc acgtattaaa aactttgaaa atggtaatct aaacttcttg
    13081 gaggctgacg cataatgaca cattcaacaa agcaggaaca ttctcactcg caatcagctg
    13141 tccttggctt acagcatgtg ctttcgatgt atgccggatc tattttagta ccaattatga
    13201 tcgcaggtgc tttaggttat tccgctagag agttgaccta cctgatttcg acagatattt
    13261 tcatgtgtgg tgtggctact ttcttacagt taaagttaac caagcatacg ggagtgggat
    13321 taccagttgt tttaggatgt gcttttcaat cagtggcacc tctatccatt attggagcgc
    13381 aacaaggttc aggtgccatg tttggagccc tcattgcgtc aggaatttat gtcattttag
    13441 tggcaggtat tttttctaag attgctcgtt tcttcccacc aattgttaca ggatcggtca
    13501 ttaccgttat tggcttaagt ctcgtaggtg ttgctatggg gaatatggga gataacgtca
    13561 aagagcctac ggcacaaagc atgatgttat cattgttgac gattgtcatt attcttttag
    13621 tccaaaaatt taccaaaggt tttgtgaaat ccatttccat tttgattggg cttgtagtgg
    13681 gaactttggt ttcagccatg atgggattag tagatacaac tcctgttgta gaggcttctt
    13741 ggattcatgt gctaacccca ttttattttg gcatgccaac ttttgaaatc acttctattg
    13801 tgatgatgtg tatcatcgca acggtttcta tggttgaatc aacaggtgtc tacttagcgc
    13861 tttcagattt gactaatgat caattagatg aaaaacgttt gcgcaatggt tatcgctcag
    13921 aagggatcgc agtctttctc ggtgggttat ttaatacctt cccttacact ggtttttctc
    13981 aaaacgttgg acttgtccaa atctcaggta ttaaaacccg tcgtccgatt tactacgcag
    14041 caggtatcct tgtggtcatt ggcctactcc ctaaatttgg agcaatggca caaatgattc
    14101 caagcccagt tcttggtgga gctatgcttg ttctctttgg tatggttgct cttcaaggaa
    14161 tgcaaatgct taatcgtgtt gatttccaaa agaacgagta taattttatt attgctgccg
    14221 tttccatctc agcaggttta ggctttaatg gcactaatct ttttgccagc ttaccagaga
    14281 cagctcaaat gttcttaacg aatggtattg tgattgccac tttgacatct gttgtcttaa
    14341 atttagtttt aaatggcaaa gacaaacaag atgaataatt aaaaaacggc taattgagcc
    14401 gttttttctg tgatcagttt tgagcaaacc gttaacccct tttaatgata gtatggttga
    14461 aaatagtgtc tcaaaccatt tgacataagg acatggtgct ttcttgttac tagaagacct
    14521 tcaatattat caaaggtatt taaaagtgtg ataatcattg agctatcaag accaaataaa
    14581 cgggtagccc atatgtcaca ataaaaagaa gaaggagcca tgatcgttaa gctaagcata
    14641 tctgtttcta taggatagcc tgtctgacga tctaagatat gatgatactg tttccctttg
    14701 gctgtaaact gcctttcata aattccagaa gtcacaacag agtgattgtt aaccttgatg
    14761 acaccaagat gttgcccacg tttagcatct ggtttttgaa tgccaattcg aaaagtcttg
    14821 tcagggcttt tcggattagg tccatgaacg cgtacatttc cacctaaatt aataagggca
    14881 gagtcaatac catcttcaat caggtaggcc ataatcttat cagtaatata accttttgct
    14941 aaggctccta agtctaaagc cattcctact tgttgtaaaa agacagtctg ttttttgtca
    15001 tctataagaa cctgtctagg atctgttaga gctaactgtt gtgagataag gttatgacta
    15061 ggcactctag catcttcaaa tccaattcgc caggcttgaa caagtggccc aatggcgata
    15121 ttaagattac ttggtgttga caagctatga gctttaccaa tttggattag gttaaataaa
    15181 tcagagtgaa cgctgagggg tttaacacca gccgcctgat taatagccat caattcagag
    15241 tttgaatcat tagctgaaaa acgatttttg taagtatata ataagtcaat gactctactt
    15301 agttgttggc aagctttgtc agattcgatc tgaatatcaa taactgttcc cattagcttt
    15361 aattgttgcg taacaaacat aattagtcct ctttttagca gaataccccc actaaggagt
    15421 gggggaaggt cattatgatt tttgtttcat ttcaccttga ggatagtaag ttccttcagg
    15481 catatcgttg ataaaaacat ggatattttc tttaggtgct tttgcaatgc gtgagactac
    15541 ttcggtaacc tcgcgagcta attgattttt ttgttcttgt gagcgtccct caaacaagtc
    15601 aattgttaca aatggcataa tgttactcct ttatgttatt gggcatcatt gtaacataat
    15661 gctgtgaaaa agtatacact gttttcaatg gctgggaaaa cttcagcctt tgtggtaaaa
    15721 taggtagaat actatagaaa gtaggatttt ccgctttggc tcaactctat tataaatatg
    15781 ggacaatgaa ttctggtaaa accattgaaa ttttaaaagt tgctcataac tatgaagaac
    15841 aaggcaaacc tgttgtcatt atgacaagtg ctcttgatac acgtgatggt tttggcatcg
    15901 tctcaagccg tattggtatg cgacgagaag ctatccccat ttcaaatgac atggatattt
    15961 tcacatttat tgcccaattg gaggaaaaac cttattgtgt cctgattgac gaaagccaat
    16021 ttttaagcaa gcaaaatgtt tatgatttgg cgcgtgtggt ggatgagcta aatgttcctg
    16081 tcatggcttt tggtttgaaa aatgatttcc aaaacaatct ttttgaaggt tcaaaacatt
    16141 tgctattatt ggccgataag attgatgaaa tcaaaacaat ttgccaatac tgtagtaaga
    16201 aagcaaccat ggttttaagg acagaaaacg gaaaacctgt ctatgaaggt gatcagatac
    16261 aaattggtgg taatgaaaca tatatcccag tttgtcgaaa acattatttt aatccagaga
    16321 tttaaaaggt aatcggtttt aaaggagata caaagaaaaa tgaatattta tgatcaattg
    16381 caggcagttg aagatcgtta tgaagagtta ggtgagttac ttagtgatcc agatgttgtt
    16441 tcagatacaa agcgatttat ggaattatca cgtgaagaag ctaatactcg agaaactgtc
    16501 acagcttata gagaatataa gcaagtcatt caaaccattt cagatgctga agaaatgatc
    16561 aaagatgcca gtggtgatcc tgaattagaa gaaatggcta aagaagaact taaagaatca
    16621 aaagcagcta aagaagagta tgaagaaaaa ttaaaaatcc ttctattacc taaagatcct
    16681 aacgatgata aaaacattat tttagaaatt cgtggtgctg ctggtggcga tgaagcagcg
    16741 ctttttgctg gtgatctttt aacaatgtat caaaaatatg ctgaaactca aggatggcgt
    16801 tttgaagtta tggaatcatc cgttaatggt gttggtggta ttaaagaagt ggttgccatg
    16861 gtttctggtc agtcagttta ttctaagctt aaatatgaat caggagctca tcgtgttcaa
    16921 cgtgtcccag tgacagagag tcagggtcgt gttcatactt caactgcaac tgttttggta
    16981 atgccagaag ttgaagaagt agaatacgac attgatccta aagaccttcg cgtcgatatt
    17041 taccacgcgt ctggtgctgg tggtcagaat gtcaataaag ttgctactgc agttcgtatg
    17101 gtacacattc ctacaggaat caaagttgaa atgcaagaag agcgtactca gcaaaaaaac
    17161 cgtgataaag cgatgaaaat cattcgtgct cgtgttgctg accattttgc gcaaattgct
    17221 caagatgaac aagatgctga acgtaaatca acagttggta ctggtgatcg ttcagaacgt
    17281 attcgtactt ataatttccc acaaaatcgt gtaacagatc atcgtattgg tttgacactt
    17341 caaaaattag atactatttt atctggaaaa atggatgaag ttattgatgc actcgttatg
    17401 tatgatcaga caaagaaatt agaatctctc aataactaat gaactatgct acattaatca
    17461 gaacttatga agataaacta gaacaaatag atgaggatcg cgaaaatctc tcctatgttt
    17521 ttagagaaat caaagaatgg tcaagtctag atatgttgat tcaccaaaat caagctgtga
    17581 ctcctgaaga tgctgttctt ttggaacata ttttctgttc tctaagtcag catttatctc
    17641 ctcaatatat tacaggtaat gcttattttc gtgatttgaa gcttgcagtc gacaagcgtg
    17701 tattaattcc aaggccagaa acagaagaat tagttgacat gattttagct gaaaatcttg
    17761 atgcaccgtt gaatgtttta gatattggta caggtagtgg agcgattgct atttctctca
    17821 aaaaagaaag gcctaactgg caagtaacgg catctgatat ttctagagct gctcttgact
    17881 tggcaaaagc caatgctgat gcttaccagc ttgatataac gtttattgaa tcagatgttt
    17941 ttagtctcat ttcaggaaca tttgatatta ttgtgtcaaa tcctccctac atatcctacg
    18001 aggataagga agaagtcagt ctaaatgttt tgcaatcaga gcctcatttg gcactttttg
    18061 ctaaagaaaa tggctatgct atttaccgta agattattga acaagctgac aattacttaa
    18121 ctaaggaggg gaagctttac tttgaaattg gttataagca agctgaaggt ataaaagata
    18181 tgttacaagc ctattttcct caaagacata tacgagtcgt aacggatata tttggcaaag
    18241 aaagaatggt ggttgttgat tatggagtat ctagctagta tcattgaatc aggtgatgcc
    18301 cttgttttgc caacagaaac ggtttatggt ctttttgcca aggctttaga tgaaaaagca
    18361 gtaaatgctg tttatgactt aaaacaaaga ccccgagata aagcaatgaa ccttaatgtg
    18421 gctgatttta atagtatctt agccttttca aaagaacagc cgagatacct caagaaatta
    18481 taccaagcct ttttaccagg tccgttaacg attattttaa aagctaatga ccaggttcct
    18541 tattggatta attcgggtct ttcaacggtt ggttttcgct tacccagtca tccaattacc
    18601 acagctttaa ttcaaaaaac aggcccttta attggtcctt ctgcaaactt atctggcaaa
    18661 gctagtggtc gagtttttga tcatattatg caagattttg actttcaagt gtttggttat
    18721 gcagatgatc cttttctaac aggtaaggat tcaaccatct tagacttatc aggtgagcgt
    18781 gctgtgattt tacgtcaagg tgctatcacc aaagaagaat tattagccaa cgtgcctgaa
    18841 cttcgctttt aagagaggag ccgcttggaa tgttgagacc attaagtaaa acggactgtc
    18901 ctatgctaca agaaattaac gccaaagccc ttggctattt agtttcgctt gacttgttag
    18961 aaaggcaata tgaacgattg attgaggatt gccatcacta ttttttagct tatgccgaca
    19021 aggataccaa tcaattatta ggctatgttc acgctgaacg gtatgagacc ctttatgctt
    19081 ctgatggtct taatctcttg ggcttggctg ttttaccagc ctatcagaga aggggaattg
    19141 ggagtgcctt actaagggcc ctggaatccc aagctaggca ggaaggcatt gcctttattc
    19201 gcctcaattc tgccagtcat cgtaaagaag cgcatgcttt ttaccgaaac ctcgactatg
    19261 cagatgataa aacacaatta cgattcatca aaaacttaca aggagatgac aatgattttt
    19321 gataaaggta atgttgaaga ctttgataaa gagctttggg atgccattca tgctgaagaa
    19381 gaaagacaag aacatcatat cgaattgatt gcatctgaaa acatggtttc aaaagctgtc
    19441 atggcagctc aaggttctgt tttaaccaat aagtatgcag aaggctatcc aggtaatcgc
    19501 tattatggtg gaacagaatg tgtggatatt gtcgaaacgc ttgctattga acgtgctaag
    19561 aaacttttcg gtgccgcatt tgccaatgtt caagcccatt ccggaagtca agccaatgca
    19621 gcagcttata tggccttgat tgaggctggt gacaccgtat taggaatgga tttggctgca
    19681 ggtggtcatc tcacgcatgg ctctccagta aatttttctg gaaaaaccta ccattttgtg
    19741 ggttactcag tagatgctga tactgaaatg ttaaattatg aggcgatttt agaacaagca
    19801 aaggcggtcc agccaaagct tatcgttgca ggggcttcgg cctactctag aagcattgat
    19861 tttgaaaagt ttcgtgccat tgctgatcac gtaggtgctt acttaatggt ggacatggct
    19921 cacatcgctg gccttgtagc agcaggtgtg cacccgagtc ctgtccatta tgcgcatatt
    19981 gtgacatcaa caacccataa aaccttacgt ggtcctcgtg gaggcttgat attaaccaat
    20041 gatgaagctc ttgctaaaaa gattaattcg gccgttttcc ctggtttaca aggaggacct
    20101 ctggaacacg tgattgctgc caaagcggtt gccttcaaag aagccttgga tccagccttt
    20161 aaagactatg cacaagctat tattgataat actgcggcta tggcagcagt ttttgcacaa
    20221 gatgatcgtt tccgtctgat ctcaggtggt acagataatc atgtcttttt agtagatgtc
    20281 actaaggtta ttgctaatgg taaactagcg caaaatcttc tggatgaggt taatattact
    20341 ctaaataaaa atgccattcc ttttgaaacc ttatctcctt ttaaaacatc aggcattcgt
    20401 attggttgtg cagctataac cagtcgtggc atgggagtta aagaaagcca aactatcgct
    20461 cacctcatca tcaaagcctt ggttaatcat gatcaagaaa ctattcttga agaggttcgt
    20521 caggaagtgc gtcagttaac cgatgccttc ccactctata aaaagtaagg aatcatgtta
    20581 gatagttata taaaacgtat tgtcattcat caattttctc ccaatgacac tgagttactg
    20641 ttatcagatc gtttagtgag cattacacca cgaattgatg aatatttccg gaaaaaattg
    20701 gctaaagtgt tctcggatga agccaaacgg ggtcagtttg aggctaataa tacctttttt
    20761 acaaccattg gtgatgattt gttggaaacg tctgttacca ttgcccagtt atggaaggaa
    20821 gcctttgtta tttcagagga tcaaaaaacc aatgatttag tctttgtcca gtttgataag
    20881 gatggcgaac ccttttttgc tttcttgcga attgctttga aagaacagtt tgctcacctt
    20941 tctgacaatt atgaacatcc atttacggtg acgcagaata atctgccgag tcccacccag
    21001 acaccagatg aagcactagt cattaatctc aaatctggtc agtactactt gattgaaaag
    21061 cgtgtgaagc ataatggcag ttttgctaat tatttttcag aacacctctt gaaagttaca
    21121 cctgagcaat ctgttaaaaa gtctatcaaa atgatagaac aaaccgctca aaaaattgca
    21181 gagcatttta atcaagatga ttttactttt cagtcaaaga tgaaatccac tctttttaag
    21241 cagttagaag cagacgacgt tttatcacca gaaaaattag ctgaccaact ctttgatgat
    21301 aatttaacag cccgtttaac ctttgtggat caagtcaaag atgtcattcc agaacctata
    21361 aaaattagcg atattgatca ttctagacag ataaaaaaac tagaaaatca aaagctatcg
    21421 ttatcaaacg ggatagaatt aacagtacca aatgccattt atcaggatgc tgaagcggtt
    21481 gaatttttgt taaatgatga tgggacttat tcaatcttga ttaaaaatat agaggacatt
    21541 aaaaccaaat agatgtttag acttttaaag cgtgcctgca gttttcttct tctttttgtc
    21601 atttatcaat cctttgttat tcatcacaat gttcaacgtg ttttggcata taagcctatg
    21661 gttgagaaaa cattagcaga aaatgataca aaggcaaatg tagacttagt cttagctatg
    21721 atatacaccg agacaaaagg aggagaagca gatgtcatgc aatccagtga aagcagttca
    21781 ggacaaaaaa ctcgattaca gatagtcagg ccagtattga gcacggggtg aatttactgt
    21841 ctcataatct tgctctagct gaggaagcag gagtagattc ttggacggct gttcaggcct
    21901 ataattttgg aacagcttat attgattata ttgctaaaca tggaggtcaa aataccgttg
    21961 atttagcgac tacctattcc aaaaccgttg tggcgccaag cctaggcaac actagtggtc
    22021 aaacctattt ttattaccac cccctcgcct tgatttctgg aggtaagctt tataagaatg
    22081 gcggcaatat ctattactca cgagaagttc atttcaatct ttatttaatt gaactgatga
    22141 gcctttttta gaaagttatc atgaaacgat tacgtccata tttgaaaggg tacctaaaag
    22201 aaagtatctt aggtcctctt tttaaattat tagaagcttt atttgaatta ttagtccctt
    22261 tgttaattgc taatatgatt gatatatcga ttagtcaaca caacagccag ggaattttga
    22321 gggttgtttt aacattattt ggtttagcaa ccattggctt attgctttcc gttacagccc
    22381 agtatttttc ttcgaaagca gctgttggtt ttacaagaca aatgacagat gatttgttta
    22441 aaaaaatcat gtttttgagc aaggaggacc aagaccatct tggttatgct agtctggtat
    22501 cacgattgac cagtgatagt tttcaaattc aaactggtat caatcaattt ttgcgtcttt
    22561 ttctaagggc ccctattatc gtatgtggtg ctatggtaat ggcttattgg attagtccaa
    22621 gtctaaccct atggtttgtg atgatggtga ttgtcttact aacacttgtt tttgttatgt
    22681 cacatttatt aggtcccctt tatctcttaa tccgccgaga aacagatcac ttggttcgtt
    22741 tgactagcca acagttacaa ggaatccgag taattaaggc ttttaatcaa acccaaaaag
    22801 aactccaagc atttaagcag caaaatatgc tcttaagtcg ccaccaatat caagctgcta
    22861 ccctagccaa tgtcttgaat cctatgactt ttttagtggt caatcttact ctgttaatct
    22921 tgatttggca aggaagttgg caagtagctc atagatcgct tagtcagggc atgttggttg
    22981 ctttaattaa ttacctcttg cagattttgg cagaactttt gaaaatgacc atgttgatgg
    23041 gaaccatcaa tcaaagtgta acagccgcaa aacggattaa tcaggtgttt gttttagctg
    23101 atgaagtgcc tttgccctta cttaaagatg gtcctatttc aactcatctg ttgaccatcc
    23161 ggcacttgac ctttacttat ccaggagcag cagagccaag tctgtatgat attcagttaa
    23221 gtgctgatca gggagaatgg attggcatca ttggtggtac tggagcaggc aaaacgactt
    23281 tgattgactt gatctgccaa acttattcac aatatagtgg tgagattagt cttaattggc
    23341 aaggagaagt gccaaaaaca ctaaccgagt ggcgaaatgt gattgctctt gttcctcaaa
    23401 aagctcaatt atttaaagga acgattagaa gtaacctcct actgggacaa tcaatgccta
    23461 ttaatgatga ggagctgtgg cgggctcttg aattagctca agcaaaagag tttgtcgctg
    23521 ccttaccaga acaattagag gcacctgttg aagcctttgg ccgtcatttt tcaggagggc
    23581 aacggcaacg tctagctatt gccagagcac ttctgaagcc aaaacccatt ttgattttgg
    23641 atgatgccag ttccgcctta gacaatgaga ctcgaggacg actttttaaa gctctaaaag
    23701 aagagttatc agatgtttta gtgattctag tcacgcaatc cattaagaat ttgcagtttg
    23761 ctgataagat tttagtgttg gaacagggcc atcaattgga ttttgccagt catgaccagt
    23821 taaaagtaag caatgcactt tatcaagaaa tgctagcgct ttacgtgaag ggggagtaaa
    23881 aatgattaaa acagaccatc acctcctaaa gcgagtgctt caggatttgt taaaaaaacc
    23941 tctacctgtt tgtattctcg tgatagctag ttttgtacaa gttggtttaa gtgtttactt
    24001 gcctgttctt atcggtaaag ccgttgatat gagtttgtca gtcaattctt ggcaaacttt
    24061 aaaatggctg ttggggcaaa tgttagttgt tattgtggtc aacacattga ttcaatgggt
    24121 gatgcctctt gtctatagtc gtttgctata tcaatatagc cagcaattga aagataagct
    24181 tttggaaaaa attcatcgtc ttccttttgc atatctagat cgtcaaacca ttggagattt
    24241 ggttagtcga gtgataaccg acactgagca actgatcaat ggtctacaat tggtttttaa
    24301 ccagtttata cttggactat tgacgattct gtgtaccatt atagctatgg cacagattga
    24361 ctggctcatg ttaatcttgg ttttggtgtt aataccaagc tccctctttt tagctcgttt
    24421 tattgctcaa aagagttttc attatgcaca agcacagacc aaaagcagag gaaatttagc
    24481 tcagtttact gaagaagtcc ttcgtcaaga aggtttggtt caactgttta atgctcaaga
    24541 gcagtctatc tgtgattatc atgttttaaa taaaacctat tgcgaggctt cacaaaaagc
    24601 cattttttac gcctcaacag tcaatccagc cactcgcttt attaatagtg tcatttatgc
    24661 tttactggca ggtttagggg ctgttcgtat catggctgga cttttttcag taggtcagct
    24721 aaccactttt ttaaatgttg ttgtccaata taccaaacct ttcaacgata tttcatctgt
    24781 cttggcagag atacagagtt ctttagcttg tgcgcaaagg ctttatgacc ttttagatat
    24841 tgaaataaaa gagcaagagc actttctaac atttaaggca tcagcggtta agggacaaat
    24901 tgactttgaa gaagtaagtt tttcttatca aaaagacagg cccttactga aggatattaa
    24961 tttttctgtt cctgcgggtt ccaaggtagc gattgtaggg cctacaggtg caggcaaatc
    25021 gactttaatc aatttactca tgcgctttta tgaacttgat gctggtagca tcaagttaga
    25081 taaagttcct attaagtgtt atgctaagga agaacttagg tccattactg gcatggtatt
    25141 gcaagaaacc tggttgaaag atgcgactgt tcatgagttg attgcttacg gcagtgaaga
    25201 ggctagccgt ggtgaagtag tggcagcagc caaagcagct catgcacact tctttattat
    25261 gcaacttcct aagacttatg atacttactt aagtgcttct gatgatgctt tgtcccaagg
    25321 gcagctccag ttattagcta ttgccagaat gtttttgaaa aaaccaaaag tcttgattct
    25381 agatgaagcc acctcctcta ttgatattag aacagaagct gttattcaag aggcactaaa
    25441 agaactcatg agaggaagga ccagctttat cattgcccat cgtttatcaa cgattcaatc
    25501 agctgatttg attcttgtta tggatcaagg tcgattggtt gagtggggaa cacatgccag
    25561 cttaatgtca aaaaacggat gttatgctag attacaaaag atagaataaa gttcgtcttt
    25621 taacaaaggt gaacttttta agtcttccta aagttagtta attaacaaac tttaaactgt
    25681 tatataaaaa aataacagcg aaaaagcgga cgatcttttt ttataagtga gaaaaaacag
    25741 ttgactaaag aagaaataac tcaaaaaagt gagcaatata tttggaagcg ttttttgact
    25801 gtggtataat agagccctat ataatattgt gaaatgagga acaaaatata tgagtaaaat
    25861 cgttgttgtt ggtgcaaacc atgctggtac ggcctgtatc aagactatgt taacaaacta
    25921 cggtgatgct aatgagattg ttgtatttga ccaaaactca aatatttcat ttttaggctg
    25981 tggtatggca ctttggattg gtgagcaaat tgctggacca gaaggacttt tctattcaga
    26041 taaagaagaa ttagagtctt taggggctaa agtttacatg gaatcacctg ttcaatcaat
    26101 cgactacgat accaaaacag tgacagcgct tgttgatggt aaaaaccacg tggaaactta
    26161 cgacaagttg atttttgcaa ctggctcaca acctatctta ccaccgatta aaggtgccga
    26221 aatcaaagaa ggatcacttg aatttgaagc aactcttgaa aatcttcaat ttgtgaagtt
    26281 ataccaaaac tcagctgatg tgattgcaaa gcttgaaaac aaagacatta aacgtgtagc
    26341 cgtagttggt gctggttaca ttggtgttga gttagctgaa gctttccaac gcaaaggcaa
    26401 agaagtggtt ctgattgatg tcgtggacac ttgcttggca ggttattacg accgtgattt
    26461 gactgactta atggctaaaa acatggaaga acatggtatt caactagcct ttggtgaaac
    26521 agttaaagaa gtagctggta atggtaaggt tgaaaagatc attactgaca aaaatgagta
    26581 cgatgtggat atggttatcc tcgccgttgg tttccgtcca aacacaactc ttggaaatgg
    26641 taagattgat cttttccgta atggtgcttt ccttgtcaat aaacgccaag aaacttctat
    26701 tccaggtgtt tatgctattg gtgactgtgc aactatctac gataatgcta ctcgcgatac
    26761 aaactacatt gctttagctt caaatgctgt ccgtacagga attgtagcag cacataacgc
    26821 ttgtggtaca gaccttgaag gtattggcgt tcaaggttca aacggtattt ccatttacgg
    26881 cttgcacatg gtatcaactg gtttgactct tgaaaaagct aaacgacttg gttttgatgc
    26941 tgcagtgact gagtatactg ataatcaaaa acctgaattt atcgaacacg gtaacttccc
    27001 agtaaccatt aagattgttt acgataaaga ctcacgtcgt atcttgggtg ctcaaatggc
    27061 agcccgtgaa gatatgtcaa tgggaattca catgttttca cttgctatcc aagaaggagt
    27121 gaccattgaa aagttggcat taactgatat tttcttctta ccacatttca acaaacctta
    27181 caactacatc acaatggcag cacttggtgc caaagactag tatctgatag gaaaaagcca
    27241 gagcagttca gcagcactgg cttttttgct ttttaattgt tgcaacctga aaagttctaa
    27301 acttatgatt atcctcttat agcacgttgg aaaaggaata tcaggcaaaa caaaaagaga
    27361 ccgaagtctc ttttgtgatt agtttttagc agcagaagca aattcttcct tagcaaaggc
    27421 ttcatcaatg atagctttca attgatttgc agaggcttgc attttttgca attcagcatc
    27481 gttaagtgga atgtttactg gacgaacaat tccatacgct ccaacgatag ctggttgacc
    27541 aatatagcaa tcttcaacac cttcgtattg gccttcttgg aaaacagaaa gcggaagaac
    27601 agcattttca tcatcaagaa tagcttttgt aatacgagct agggcaactg caataccgta
    27661 gaaagtagca ccttttttat tgatgattga gtaagcagca tcacgtacag aaatgaaaag
    27721 atcaactagg ccttgctcat caatgtcacg attagcttgg agccagtcgt aaagacctac
    27781 accagcaacg ttagcgtgtg accaaacagc aaattcagag tcaccgtgtt ctcccatgat
    27841 gtaagcgtga accgaacgcg catcaacacc gattttagca gccagagctt gacggaaacg
    27901 ggctgaatct agagatgtac ctgaaccaat gacacgctct ttagggaaac ctgagaattt
    27961 ccatgttgag taagtcaaaa cgtcaactgg gttagcagca acaagaaaga ttcctttgaa
    28021 accagatgca acgatttgtg taacaacctc tttattgata cgaaggtttt tttcaaccag
    28081 gtcaaggcgt gtttcacctg gtttttgagg agcaccagct gttaagacaa caagatcagc
    28141 atcatgacag tctgagtagt cagctgcata gattttttta ggtgatgtaa aagctagagc
    28201 gtggcttaaa tcttctgcat ctccttgagt tttttcttta aaaatatcaa taataccaag
    28261 ttcttgagca atattttgtg ttaccaatgc aaaagcgtat gatgaaccga cggcaccatc
    28321 accgaccaag attacttttt tgtgttgttt agttgcagtc atttctaaac atctccttaa
    28381 ttttattaga gcaaaagctc atacggtctt attttaacat attgataatt gtttgtcatt
    28441 gaattcagaa aaataatgaa aatagtttac tgataacgct tccaataaga aaaaataagg
    28501 aatttatggt ataatgaaat ctagtattga ctagaaaagg agcattcctt aaatgcaaga
    28561 tcgaaattta attgacgtca atctgacaag tgaaatgaaa acgagtttca ttgactatgc
    28621 catgagtgtc attgtggcaa gagctttgcc agatgtgcgt gatggtctga aacctgtgca
    28681 tcgtcgtatt ctctatggga tgaatgaact cggtgtgaca cctgataaac cgcataaaaa
    28741 atctgctcgt attacgggtg atgtcatggg taaatatcac ccgcatgggg attcttctat
    28801 ttatgaagct atggttcgta tggctcagtg gtggagttat cgccatatgc ttgttgatgg
    28861 ccatggcaat tttggttcta tggatggtga tggtgctgcc gctcaacgtt atactgaagc
    28921 gcgcatgagt aaaattgcgc ttgaattatt aagggatatc aataaaaata ccgttaattt
    28981 tcaagataac tacgatggaa gcgaaagaga accagtagta ttaccagctc gctttcctaa
    29041 tttattagtc aatggagcga cagggattgc cgttgggatg gcaactaaca ttccgcctca
    29101 taatttggca gagtctattg atgctgtcaa gatggtaatg gaacatccag actgtacaac
    29161 aagagagttg atggaagtga tccctggacc tgactttccg actggtgccc ttgttatggg
    29221 gcgctcaggt attcataggg cttatgatac tggtaaaggt tctatcgttt tacgctctcg
    29281 aacagaaatt gaaacaactc aaacaggtcg ggaacgtatt gtggttactg aatttcccta
    29341 tggcgtcaat aaaacgaaag tgcatgaaca cattgttcgt ttagcacaag aaaaaagact
    29401 agaaggtatt acagcagttc gtgacgaatc tagccgtgaa ggagtgcgtt ttgttatcga
    29461 gattcgtcga gaggcatccg cgacagttat cttaaataac ctctttaaat taacaagcct
    29521 tcagacgaat ttcagtttta atatgttggc tattgaaaat ggtgtgccta aaatattgtc
    29581 actcagacaa atcattgata attacattag tcatcaaaaa gaagttatta tacgtcgcac
    29641 ccgatttgat aaagataaag ctgaagccag agctcatatt ttagaaggct tactgattgc
    29701 ccttgatcat ttagacgaag tgattgctat tattcgtaac agtgagacag atgtcattgc
    29761 tcagacagaa ttgatgtcac gtttcgactt gtctgaacgc caaagccaag ctattttgga
    29821 tatgcgtttg cgtcgtttga ctggtttgga acgtgataag attcaatcag aatatgatga
    29881 tttgttggcc ttgattgctg acttatctga tattttagcc aaaccagaac gtattatcac
    29941 tatcatcaaa gaagaaatgg atgagatcaa gcgtaaatac gctaacccac gccgtacaga
    30001 attaatggtc ggtgaagtcc tttctctaga agatgaagac ctaattgaag aagaagatgt
    30061 tttgattacc ttgtcaaata aaggttatat caagcgtctt gctcaagatg aatttcgtgc
    30121 ccagaagcgt ggtggacgtg gcgtccaagg aactggagtc aacaatgacg actttgtccg
    30181 tgaattggta tcaacaagta cccatgatac tttgctcttc tttacgaatt ttgggcgtgt
    30241 ctatcggttg aaagcttacg aaattccaga atatggtcgt acagcaaaag gtcttccaat
    30301 tgttaatcta ttgaaattag aagatggtga aaccattcaa actattatca acgcacgtaa
    30361 ggaagaaaca gcaggtaaat ccttcttctt tacaacgaaa caaggcattg tcaaacgtac
    30421 agaagtttca gaatttaata atatccgtca aaacggtctc cgtgctctta agttgaaaga
    30481 gggagatcag ctgattaacg tccttttgac aagcggtcag gatgatatta tcattggaac
    30541 tcactccgga tattctgttc gttttaatga agcaagcatc cgcaacatgg gccgatcagc
    30601 tacgggtgtt cgcggggtta agcttcgtga agatgatcgc gttgttggcg cgtcacgtat
    30661 tcaagataac caagaagttc ttgtaattac cgaaaatggc tttggtaaga gaacaagtgc
    30721 tacagactat cctacaaaag gtaggggggg aaaaggaata aaaacagcta atattacccc
    30781 taaaaatggt caattagctg gattggttac cgtagatggt acagaagata tcatggtgat
    30841 tacaaataaa ggtgtcatta ttcgcacaaa tgttgcaaat atttcgcaaa caggtcgtgc
    30901 tactttgggt gttaaaatta tgaaactaga tgctgatgct aagattgtaa catttacctt
    30961 ggttcagcct gaagatagta gtatcgctga aatcaatact gatcgtgaaa atagtatttc
    31021 aaaaaataaa gataattaat cataacaagg agtaaaaaat ggtaaaaaaa caaaagcgtc
    31081 gaaaaataaa atccatgtct tgggcaagaa aactactaat agctgtactt ttaattctag
    31141 gtttagcatt gctttttaac aaacctatcc gaaatacatt aattgctcga aactctaata
    31201 aatatcaagt aacgaaagtt tcgaaaaaac aaatcaaaaa gaataaagag gctaagtcaa
    31261 catttgattt ccaagccgta gagccagtta gtacagagag tgtcttgcaa gcacaaatgg
    31321 cggctcagca acttcctgtt atagggggca ttgccatacc agagcttggc attaatttac
    31381 caatttttaa aggtttagga aatactgagc ttatttatgg cgcaggaacg atgaaagaag
    31441 aacaagttat gggaggagaa aataattatt ctcttgccag tcatcatatt tttggaatta
    31501 caggttcatc tcaaatgctc ttttcgccgc ttgaaagagc acaaaatggg atgtccatct
    31561 atttaacaga taaagaaaaa atttacgaat acatcataaa agatgttttc acggtagctc
    31621 ctgaacgcgt tgatgttatc gatgatacag ctggtctcaa agaagtgact ttagtgactt
    31681 gtacagatat cgaagcaaca gaacgtatta ttgtcaaagg agaactaaaa acagaatacg
    31741 attttgataa agcgcccgcc gatgtattga aagcttttaa tcattcttat aaccaagtat
    31801 ctacctagat atatcttaaa tataatattt aaaaagtagg accatagaga aaatttatct
    31861 catcctactt tttttgaaag gagaaatatg atgaaactaa atgccattca tcacgttgct
    31921 attattgtat ctgattatca tctgtcaaaa gatttttatg tgaataaact cggatttgaa
    31981 attatcagag aaaattatcg ttctgacaag catgattaca aattagattt atcttgtggt
    32041 cgtattgaat tggagatttt tggtaaggtg acaagtgacc ccaactatca agctcctcct
    32101 aaacgtgtaa gtcaaccaga atttaaaagt gaggcctgtg gtttgaggca ccttgctttt
    32161 cgtgttacca acattgagag ttatgtagat gatctaaaga gcttaggaat tccagtggag
    32221 cctattaggc atgatgatta cacaggtgag aaaatgactt tcttttttga tccggatggt
    32281 ttgcctttag aattacatga atagacttat taggttaacg actggatcgt gctattaaac
    32341 tcgttaaaaa tagttatttg ttgtatcttc ttttgcttga ttaatctctt ttgatcgtta
    32401 aatgatttgg ttaactttca aagtgaagag caatttttgg agtaatcttg tcgaagtttt
    32461 ttaatagaat aactatagga aaagcaaaat atttgacgat aaactcttac agtgttataa
    32521 tgacaatata agtaaataac tgtgttgtca ctttgttgaa atgttttcgt attaatgttt
    32581 ttttatctat tacgatagat aattttactt caatttttga ttgaaaatac taaaataagt
    32641 gatgtggtca ctttgacaac catttattgg tccttttaga taagacaatt ttgtggctct
    32701 tcagttgaaa ggatgtgttg ttgatgttag aggaaacaat catgttaaat taactcaggc
    32761 ttaaagacca aaaaaggagt gaagtctatt atgaaaaaaa gaaattttaa acttacagaa
    32821 atgttacaat tggttttatt agtggttcct gctgtaaaac ttgctaaaaa aatgtttaac
    32881 gatagtaaaa caccgtctaa aagaaagtag gtctacaatg actaaaaaaa atcatggcgt
    32941 tttttggggg ttgttgcttg gatcagcagc agctagcatt gcttacttaa gtttatcgtc
    33001 ttccaaaaaa gatcaactct tgaaagatag tgctaaaaaa atagatgatc tcaacgctta
    33061 cttgcaagat aaaagtaagc aagttctgga tgcagtatcg gaaaaagtac aagaatccaa
    33121 agatgctgtt gaagtttatg gtggtattgc cgcagaaacc gttgaagaaa agtggcaaga
    33181 taccaaagat gctgttgaag tttacggtgg tattgccaca gaaacagttg aagaatcttt
    33241 gggacaggtt aaagaaaagg tagaaggaat tggcgaagct actagccaaa ctatccaatc
    33301 taaaatggaa aaactcacca gcgataagac agatgctgat gatgaaaaat aggttttaaa
    33361 atacctttaa gataagacaa aaagtgccat taggcacttt tttaatcttc tgttggaaca
    33421 ataatcgaaa tggcttttgg aatgatatct aattgaatgg gcagatagtc acttttatcc
    33481 ccatcaatcc tggtacgtgg taatatcgct tgttttttag cttgtggtag taagctaagc
    33541 gtattggctt gaaaatgact gatttcctct gctttggaaa actcaccctg tttaaaatca
    33601 ttaatatgcc ataaaaattt aaagaaagag acttttttca tggtataaac ttggaaatag
    33661 ccatcgtcag cttgagcacc aggagaaaaa gaaggaaaac cagcaatggt atttgtcatc
    33721 gtgattaaga gaaacttcgt tttcaggtga atacgatggt tgtggctaat taaagagatg
    33781 gcatagctgc gatttcgttt cagtattcga atactatctt ttaaaaatgc tagaggacca
    33841 aagcgtcgtt tttcctcagc cgttacgtcg gcagcaatat cagccagtaa tcctaaggtt
    33901 aaactggaaa tcatgtattg ctggttagct ttgcaaatat caacttgcat gatttgtcca
    33961 gtcaagatag tatccaacgc ctcagtaatt tgtaaaggga tatgcatagc cttggcaaaa
    34021 ttattgactg tccctgaggg cactaagcct attaaacaat gagctcctcc ttcatagatg
    34081 ccaccgatga ttttatttag tgtcccatcg ccaccaagag ggataaccaa gtcaatcttg
    34141 tccttagcag cttgttttgc taattgaaaa gcctggtcag catctttagg ggtaataact
    34201 tctacagaat cttcggaaaa accatgttgg caaaaatagt ctttgacttg cctagcaagt
    34261 tggttttctt tctttccaga attaggattg taaaaaatcc gaacggtttt catcaggtct
    34321 ctcctttgac agcttattac ttgctatcca ttataccact tctaagaatt gatgtcttac
    34381 atcaaatcat cacattaagc ctctcaatca gtctgagcat ctatttgtct taaagcataa
    34441 agaaagtgat agcgataaat tggagggcag aggccaataa aataaagaga tgccaaatca
    34501 tgtggaagta gggtcttttt ttggcataaa ataccgctcc aatggtataa gacaagccac
    34561 caaataacat gagaagacca aaagcaagac tagttttttg aatgatgact ggcaagataa
    34621 acacaacgag ccagcccata acgatataaa gcatcaaact gaatttttca ttgatacgtt
    34681 tggcaaaaat tttgtataaa atcccaaaaa gcgtaatgcc ccactgcaaa acaataatga
    34741 tatagcctag ccaaccagaa acaagggata aggcaacagg tgtataactt cctgcgatag
    34801 caatgtaaat catactgtga tcaataatgc gtagaatgta tttgtgaacc gaaccataag
    34861 ccatggagtg gtaaatcgta gaggacaaaa acatcaaaaa gagactgatg acaaagatgg
    34921 agataccaat agcggcttta aggtcataag tttgataagc atagctggct gaaataggaa
    34981 gtagaatgag catagcaaat gctccgatag cgtgtgtcac gctgtttgct acttcctcac
    35041 taaaagataa gggtaaactt tgtttaaagg tttggttcat tggatcacct cctgtaataa
    35101 ataaatagtt ttgtggtaat ctttgaccgt ttgacaggca acctgcacaa tcggtggaat
    35161 gtcctcctca atgggagcct tctgattcca acaggttaca aaagtattgt aaagactttc
    35221 agaatcagcc tgtgcctgaa gttcctccaa tacacgacta atatcttgaa taggaaatac
    35281 cgttttaaac aaactgatgg caattaagcg cgctagttgt tgcttttggt attttttctt
    35341 gataggttta gtcacatacc catgcttgac gtaattatta atcatagatg ccgttagtga
    35401 tttattatct gacacttctg aaaaatcagt gcactggttg acataaagta agacttgatc
    35461 caaatataag tctaaatcag ggaggtcctt ccaataaggt aatgatggaa aaatcatagt
    35521 tttgtctctc tatctagttt tgataactag attatacgat taatgaaaac ttattgcaag
    35581 caaaaactgt aaagacttaa aagaggaaag tagaaatggc gaagtgaagc taatcatgct
    35641 ataatgttaa agaattgatt gggatagatg ccttctgtcg caatcagact attttatcac
    35701 gaagaagatg atgctacgaa aggaatttaa actctatggc tactattcaa tggtttcctg
    35761 ggcacatgtc caaagccaga agacaggttc aggaaaatgt aaagcatgtt gactttgtaa
    35821 ctattttagt ggatgcacgc ttaccacttt ctagtcaaaa tcccatgctt acaaaaattg
    35881 ttggtgataa acctaaatta atgattttaa ataaagctga cttggcagat gcaactcgaa
    35941 ctaaagagtg gaaggcttat tatgaaagtc aaggtattaa aacattagcc atcaattcca
    36001 aagaacaatc aacggttaaa aaagtaacag aagcagccaa ggaactcatg gctgataaaa
    36061 ttcaacgctt gcgagagcgg ggcattcaaa aagaaacctt gcgaaccatg attattggca
    36121 ttccaaatgc tggtaaatct accttaatga atcgcttggc tggtaagaaa attgctgtag
    36181 ttggcaataa acctggtgtg actaaaggac aacaatggtt gaagtccaat aaggaattgg
    36241 aaattctaga cactcctggt attttatggc caaaatttga ggacgaattg gtgggcttaa
    36301 aattagcttt aacaggtgct atcaaggacc aattactacc aatggatgag gtcactattt
    36361 ttggtttgaa ttactttaaa acacattatc ctagtcgcct tactaagcgt tttaagaata
    36421 ttcctcttga ggaagaagct cctgaaatca ttatgacctt gacacgccaa ctgggattta
    36481 aagatgatta cgaccgtttc tacactttat tcgtcaagga agttcgtgat ggtaaattag
    36541 gtcaatacac cttagatcag gtgggagata tggatgtcga ctagtattaa agctattaaa
    36601 gaaagcctgg aagctgttac tagcctctca gaccccctct ttcaagaatt ggcaactgac
    36661 gctaggttag gtgtccaaaa agcgctaaaa agtcgacaaa aggctattca ggccgattta
    36721 gcagaggaag aacgattaga agccatgctt tcttatgaaa aagcgcttta taaagaaggc
    36781 taccaagcca ttgcaggtat tgatgaggtg ggacgtggcc ccctagcagg tcccgttgtc
    36841 gcagcatgtg tcatcttacc tcaacattgc aaaattaaag gtctgaatga ttctaaaaaa
    36901 atccctaaat ctaagcatga gaccatttat caggcagtga aagaaaaggc tttggctatc
    36961 ggtatcggta ttattgacaa tcagcttatt gatgaggtca atatttatga agcaaccaaa
    37021 ctagctatgc tagaagccat taaacagttg gagggccaac tcacacaacc agattatctc
    37081 ttgattgatg ccatgacatt ggatattgct atttcgcagc agtctattct taaaggcgat
    37141 gccaattcct tgtctattgc agcagcatca attgtagcta aggtcaccag agatcagatg
    37201 atggctaact atgatcgcat ttttcctggt tatggcttcg ctaaaaatgc aggctatggc
    37261 accaaagaac atttacaggg attaaaagct tacggcataa cgcctatcca tcgtaaaagt
    37321 tttgaacctg ttaaatccat gtgctgcgat tcaactaatc cttaaaaagt tctgttttta
    37381 gcagaatttt tttctttttt acgaataaat gaagtaagga ggtaacttag tgaatcattt
    37441 tgaactttat aagctaaaga aagctggact gactaataaa aacattctca atattcttga
    37501 ctaccaagaa caccaggaaa aatcgttgtc acttcgagat atggccgttg tttctggttg
    37561 taagcatccg tctcacttta tagaagccta taagcagtta gatattcaaa aattaaaaat
    37621 agaatttaaa caatttccta gtatttctat cttagataag cattacccaa tggcattgaa
    37681 agaaatatac aatccacctg tcctcttgtt ttttcaggga aatttagacc ttcttgagaa
    37741 acctaaatta gccattgtcg gctccagacg ctcaagcgat accggagtaa agtctgtccg
    37801 taaaattctt aaagaactcg ggaaccgttt tgtgattgtt agcggacttg ctcgaggtat
    37861 cgacactagt gctcatttag cctgccttaa aaatggggga caaactatcg ctattattgg
    37921 aacaggattg gatcgctttt accctaaaga aaatagggag ttgcaaactt tcttagggaa
    37981 aaatcatctt gtgctaacag aatacggtcc aggagaagaa gctttatctt atcactttcc
    38041 agaacggaat cgtattatcg caggccttag ccgaggtatt cttgtcgttg aagcaaaaaa
    38101 tcgttcaggt tccttgatta cttgtcaaat tgggatagaa gaaggccgag acatttttgc
    38161 tgtcccagga aacattttgg acgggaaatc cgaaggttgc cttcagttaa ttaaagaggg
    38221 agcaacatgc gtcacatcgg gcatggatat cctttcagag tactaaaaaa gttaaagttt
    38281 cttcctatat agcatttttt tattgacagt ttcttaaaaa tgggatatta tgctataagc
    38341 tttaaacaaa ctgttatagg aagtgtgtcg aattgggaac aaaaactaca actaagccaa
    38401 aaacgggtac taaaaagtcc accactaaaa agaaatcaac agcgaaaaaa aatctcgtta
    38461 ttgttgaatc acctgccaaa gctaagacta ttgaaaaata tcttggacgc agttataaag
    38521 ttgttgcttc ggtaggacat attcgtgact taaaaaaatc gtctatgtct attgattttg
    38581 ataataatta tgagccacaa tacattaata tccgtggtaa gggatccctt atcaattctt
    38641 taaaaaaaga agccaaagct gctaaaaaag tttatttagc tagtgacccg gatcgtgagg
    38701 gagaggctat ttcttggcat ttgtcacata tcttaggact tgatcctcaa gataataacc
    38761 gagtggtttt taatgaaatt acgaaagatg cagttaaaca tgcctttgtg gagcctcgtc
    38821 agattgatat ggacttggta gattctcaac aagcacgtcg tgttttggac cgtattgtgg
    38881 gatattccat ttcaccaatt ctttggaaaa aggtcaaaaa aggactttca gcaggacgtg
    38941 tccagtcggt tgctttaaaa ctcatcattg accgtgaaaa tgacatcaaa gcatttgttc
    39001 caaaggaata ctggtctatt gatggtcttt ttaaaaaagg aactaaaaag tttcaagcga
    39061 ctttttacgg tattaatggc aaaaaaacaa agcttgataa taacaacgat gtcaaagagg
    39121 tattagcaaa gctaacaaat gaagattttc ttgtcagcaa ggttgacaag aaagagcgac
    39181 gtcgtaatgc tcccttacct tacacaacat catctcttca acaagatgct gctaataaaa
    39241 tcaatttcag aacgcgtaaa accatgatgg tagcccaaca actgtatgag gggattcatt
    39301 taggagaaaa tggaactcaa ggtttaatta cctatatgcg tacggattct actcgtatca
    39361 gtccagtagc acaaaacgat gctgctcaat ttattatcaa tcgctttgga gctaattatt
    39421 caaaacatgg taatcgtgtc aaaaatacca gtggtgctca agatgctcac gaggcgattc
    39481 gtccatctag tgttaatcat acgccagact ctattgccaa ataccttaac aaggatcagt
    39541 taaaacttta tacgcttatt tggaatcgtt ttgtggctag ccaaatgaca gcagctgttt
    39601 ttgataccgt aaaggtgaat ttggagcaaa atggcgtgat ttttgttgcc aatggtagcc
    39661 aaatgaagtt tgatggttac atggctgttt acaatgattc cgataaaaac aaaatgttac
    39721 ctgagatggc agaaggagaa acggttaaaa aaatatcgac ctctccagaa cagcacttta
    39781 cgcagccacc agctcgttat tctgaagcaa ctctgattaa aacgctagaa gaaaatggtg
    39841 ttggacgtcc atcaacttat gccccaacct tagaagtgat tcaacgcagg tactatgtta
    39901 aattatctgc taagcgcttt gagccaactg agcttgggga aattgtcaac aagcttattg
    39961 tcgaattttt cccagatatt gttgatgttg cctttactgc cgagatggaa ggtaagctag
    40021 atcaagttga aatcggagaa gaacaatggc aacatgtcat cgatcaattc tatcaaccct
    40081 ttgtcaaaga attgaataag gctgagtctg aaattgaaaa gattcaaatc aaagatgagc
    40141 cagctggttt tgactgtgat gtttgtggcc acccaatggt cattaagtta ggacgttttg
    40201 ggaaatttta cgcgtgcagc aacttccctg agtgtcgtaa tacaaaagcc atcactaaag
    40261 aaatcggtgt tacttgtccg gtttgtcata aaggacaagt tatcgagcgt aaaaccaaaa
    40321 aaaataggat attttatggt tgtgatcagt atccagattg tgagtttatc tcgtgggatt
    40381 tacctattgg acgtgcttgc cctaagtcag gtgactatct tattgagaaa aaagttcgtg
    40441 gtggcaaaca agtaatgtgt agcaatgaga cctgtgatta caaggaagaa aaaattaaat
    40501 aaaaaaagaa ttggaactcc ttgtcttgtt ccaattcttt ttttatttac aaaggtattt
    40561 ttaactacaa aaatcgctag ttcgttttta aaaggcttaa aaattcctca ataactggac
    40621 tgaaactcgc atcatctcgg taagcaatcc caatagggta aaaattattt ttatcttgca
    40681 aaggaatcca aactaagtta tctacctgat taagactctc aaaatcactc gggaggatag
    40741 tcaaggtatt taaatcgtgc aaactatgaa taagaacttc ccaatcattg tgtttaaaga
    40801 caatatctgg ttcataaccg agagctcggc attttctagg aagcatttcg cctaacatgt
    40861 agtgatcgtt taaagaagca atcttatagc cttttaaatc tttaagtttt aactgaggat
    40921 gttgcgccaa agggtgctgt ttgaggagaa cgatactgac cttatagcct tttgtggacg
    40981 tttgtaatag ctcaatggta atatcctttt gaatacttag aaaggagagg agaccaatat
    41041 cgatttttcc ttgggacaat aattcttata atttgcgaga accatcctgt ataagcgata
    41101 attcaacatt tgagtgagta gccataaaga ttgaaatttg tttcatgaat tgtatagcaa
    41161 acagtgatat taattcaaca cgaatcatct ctttttttct tgatttaatt gctgaatatc
    41221 cgcaacaatt tgattaaagt catccacaag gtctttgcct ttgtgataaa gaatatctcc
    41281 agcttcggtt agtagtagct gtcaatcact ttgtgtaaaa agcgtcgtgt tcaaactagg
    41341 actctagcct tttaattgat tgagaaagag tatgttgcgt tacaaacaaa cttttagcag
    41401 cgtgggaatg attttttgtt tcagcaactg caataaaata ggttaattat ctaatatcca
    41461 tagtagatcc ttcatgattg gtcagggaat tgcgtctcta cttggtttac aacctatttt
    41521 gatgtctctc cttattgcca tgattttctg cttccttatt gtttctccaa ttacaacggt
    41581 aggaattgct cttgcgatta acttatctgg tattggttca ggtgccgcaa gctttggact
    41641 ttgcttagca ggttgggctg ttaattcaaa aggaacttca cttgctcacg tcttgagatc
    41701 accgaaaatt tcaatggcca acgttttatc aaaaccaaaa atcatgttgc caatgttatg
    41761 ttctgcagct gtacttggtg ttattggtgc tatctttaat attcaaggaa cacctgctag
    41821 tgcaggcttt ggaattagtg gtttgatcgg acctatcaat gcccttaatt tagctaaagg
    41881 cggatggtct ccagtaaata ttctacttat cattatcatt tttgtagggg cacccattgt
    41941 gcttaatatg atctttaact acctctttat taaggtgctt aaagtgattg atccaatgga
    42001 ttacaagctt aatatctaag aaaggaactt ttgatgaaat taaaattata taatgttaga
    42061 ggcgaagaag cagtcttagc aaaaaaatgg gctgatgaca atgggattga gatttccttg
    42121 acagagtctc ccttaacccc tgaaacggtt aaagaagctg aaggctttga cgggattgcc
    42181 aatgcccaaa ttggtccttt agatgatgca atctatcctc tcttaaggga aatggggatt
    42241 aaacaaatcg ctcagcgcag tgctggtgtc gatatgtata accttgattt ggccaccgaa
    42301 aatgacatta ttatcacaaa tgttcctagc tattctccag aatccattgc agaatttacg
    42361 gttactattg cccttaattt aattcgtcat gtggagttga ttcgtgaaaa tgttaaaaaa
    42421 caaaatttca cttggggact ccctatccgc ggtcgtgttt taggtgatat gacagttgca
    42481 attatcggaa ctggacgtat tggtctagct actgctaaaa tctttaaagg ttttggctgc
    42541 aaggtcgttg gatatgatat ttaccaaagc gatgctgcca aagctgtctt ggactataag
    42601 gaatctgtag aagaagcgat taaagatgct gattttgttt ccttacacat gccaccaact
    42661 gcagagaaca cacacctttt caatgctgat ttatttaaat cattcaaaaa aggggctatt
    42721 ttgatgaata tggcgcgtgg tgcccttatt gagacgcaag atttactgga tgctttggat
    42781 gcaggcttat tgagcggagc tggtattgac acttacgaat ttgaaggacc ttatattcct
    42841 aagaattttg aaggtcaaga aattacagat tcactattta aagctttgat taaccatcct
    42901 aaggttattt atacgcctca tgcagcttat tatactgatg aagccgttaa aaacctagtt
    42961 gaaggtgccc ttaatgctac agtagagatt atcaaaactg ggacaacgac aactcgtgtt
    43021 aactaacaac tgatttgacg tccattataa aggaataatt ccaaaaattc ctttataatg
    43081 gacttttttg cattagtccg ttataataga ctgtaagaaa gggggctctt atgacatata
    43141 tagcgcttat tggagatatt atccagtcca aacaattgac ggatcgttcc aaagttcaaa
    43201 aaactttagc agcttattta gacgacctca acaaaacctt tgctccttat attatttcta
    43261 aattatccct aacgttggga gatgaatttc aaggactttt tcaggtggat actcctattt
    43321 tccatctgat tgatttgatt aatcatcaca tggatatccc tattcgattt ggagtaggag
    43381 taggttctat tctaacagac atcaatcctg atattagtat tggggctgat ggacctgctt
    43441 attggcatgc tcgtgaggct attcgttata ttcatcaaaa aaatgattat ggtaatacta
    43501 cattagcttt tcggactggt catcacaacc aggatgatgt attaaacagt ttactagcag
    43561 ctggagatgc tattaaagcc aactggcgag ctagtcaatg ggaaattttt gacacgcttt
    43621 tagatttggg catttatgag gaatactttg atcaacaacg actaggaaag caattatctc
    43681 ttagctctag cgctttgtca aaacgtctaa aaagtagtca tgttaaaatt tatctgagaa
    43741 cacggcagag tgcgctaaac tgtctcaaac aaatcaagga ggaaactgat gattaatggt
    43801 gtctctcact acctagctca aacccctaca cttaccctgt ttctcatttg tcatgtgtta
    43861 tcagactacc agttacaaag tcagcaagta gctgatttaa aagaaaaaca tttgacttat
    43921 ttaggttacc acttgattgg agttagcatt cccctaattt gtttaaccct cattatccca
    43981 caagcatggt tgatgagcct attggttatg ataagtcacg cgcttattga ctggctaaag
    44041 ccaaagatgg ctaactctct aaaatggaaa agagagtgga tttttctgct ggatcaatgc
    44101 ttacatatcg ctattagttc atttgctggg ctaaggttag caggggtgac cttgcctaat
    44161 tggcttccga tatctatttt gatgaccgtt ttatttatcc tactcattac caaaccaact
    44221 aatattgtct ttaaactctt tttcagcaaa taccagcctg accaaggaga aaaaatggac
    44281 acgatcatag gagcgggggc taccatagga attctagaga gaattgttat tggggtgtgt
    44341 atgttcatgg ggcaatttgc ttcaataggt ctggtcttta ccgctaaatc tattgctcgc
    44401 tataataaaa tttcggaaag tccagctttt gcagaatact acctaattgg ttctttattt
    44461 agtattctca gtgtttttat cgcagcatgg atttgtttct tctagttgaa aagggttccc
    44521 gtagaaagag gctacacata gcctcttttg cttttttccc ctttctgtta taataagtca
    44581 ggtaactaca ttagaaagat ttgtgggtct gtcatctaag agatatcatt cccgaagagg
    44641 tattagtgac ttgtctcaat caactgcaac ttatattaat gttattggag ctgggctagc
    44701 tggttctgaa gctgcctatc agattgctaa gcgcggtatc cccgttaaat tgtatgaaat
    44761 gcgtggtgtc aaagcaacac cgcaacataa aaccactaat tttgccgaat tggtctgttc
    44821 caactcattt cgtggtgata gcttaaccaa tgcagtcggt cttctcaaag aagaaatgcg
    44881 tcgcttggat tccattatta tgcgtaatgg tgaagctaat cgtgtacctg ctggaggagc
    44941 aatggctgtt gaccgtgagg ggtatgcaaa gagtgtcact gcagagttgg aaaatcatcc
    45001 tctcattgag gtcattcgtg atgaaatcac agaaatccct gacgatgcca ttacggttat
    45061 cgcgacgggt ccattgactt cagatgcctt ggcagaaaaa attcacgcgc taaatggtgg
    45121 cgacggattc tatttttacg atgcagcagc gcctatcatt gataaatcta ccattgatat
    45181 gagcaaggtt taccttaaat ctcgctacga taaaggcgaa gctgcttacc tcaactgccc
    45241 tatgaccaag gaagaattca tggctttcca tgatgcacta acaaacgcag aagaagcacc
    45301 gctgaatgcc tttgaaaaag aaaagtattt tgaaggctgt atgccgattg aagttatggc
    45361 taaacgtggc attaaaacca tgctttatgg acctatgaaa cccgttggat tggaatatcc
    45421 agatgactat acaggtcctc gcgatggaga atttaaaacg ccatatgccg tcgtgcaatt
    45481 gcgtcaagat aatgcagctg gaagccttta taatatcgtt ggtttccaaa cgcacctcaa
    45541 atggggtgag caaaagcgtg ttttccaaat gattccaggg cttgaaaatg ctgagtttgt
    45601 ccgctacggc gtcatgcacc gcaattccta tatggattca ccaaatcttt taaccgaaac
    45661 cttccaatct cgtaacaatc caaatctttt cttcgcaggt cagatgactg gagttgaagg
    45721 ttatgtcgaa tcagctgctt caggtttagt agcaggaacc aatgctgctc gtttgttcaa
    45781 aagagaagaa gcgcttgttt ttcctcagac aacagctatt ggtagcttgc ctcattatgt
    45841 gactcatgcc gacagtaagc atttccaacc aatgaacgtc aactttggca ttatcaaaga
    45901 gttagaaggc ccacgcattc gtgacaaaaa agaacgttat gaagctattg ctagtcgtgc
    45961 tttggcagat ttagacacct gcttagcgtc gctttaacac taaaaaagag ttccttttca
    46021 gttgagttgc tgaagaggac ttttttcctt gctgatttga gcgctagcta tgcaaaagaa
    46081 tgcacaaaaa atacatgaat agactatggt cactagaagc aatattatat aatgaatagt
    46141 actcattagt tgattcagtt tggaggtttt agcatgcagc agcaagtcgc aataacagaa
    46201 acagttttac gggacggtca tcaaagtttg atggcaacgc gtttatctat tgaggatatg
    46261 cttcctgtcc ttaccatctt agacaagatt ggttattatt ccctagagtg ttggggagga
    46321 gcaacctttg atgcctgtat tcgttttttg aacgaagacc cttgggaaag actgcgcacg
    46381 ttaaaaaaag gcttacctaa tacccgttta caaatgttat taagaggcca aaacctttta
    46441 ggctaccgtc attatgcaga tgacatcgtt gacaaattca ttagtttatc agctcaaaat
    46501 gggattgatg ttttccgcat ttttgatgcc ctaaatgacc cacgaaatat ccagcaagcc
    46561 ttaagagctg tgaaaaagac gggtaaagag gctcaactgt gtattgccta tacaactagc
    46621 ccagtgcaca cgcttaacta ttacctttct ttagtgaaag aattggttga gatgggagct
    46681 gattctatct gcatcaaaga tatggctggt attctaactc ccaaagcggc taaagagtta
    46741 gtatctggta tcaaagccat gactaactta cctcttattg tgcataccca tgcaactagt
    46801 ggcatttctc agatgaccta tctagcagca gtagaagctg gtgctgatag aattgatact
    46861 gctttgtcac cttttagcga aggcacttca caacctgcta cagaatccat gtatttagcc
    46921 ttaaaagaag caggttatga tatcacatta gatgaaacgc tactggaaca ggctgctaat
    46981 caccttcgac aagtccgtca aaagtactta gcagatggca ttctggatcc cagtcttctc
    47041 tttccagacc caaggacact acaataccaa gttcctggag gcatgttatc taatatgcta
    47101 tctcagctga aacaagccaa tgccgaatca aaattagaag aagttttagc agaagttcct
    47161 cgggtaagaa aagacttggg ttatcctccc ttagtaacac cgcttagcca aatggtcggg
    47221 actcaagctg ctatgaatgt gattttagga aaaccttacc agatggtgtc taaggaaatt
    47281 aaacaatact tggcaggcga ctatggcaaa acaccagcac cagtcaacga agacttaaaa
    47341 cgaagtcaaa ttggctcagc tcctgtcacc acaaatcgtc ctgcagatca actaagtcct
    47401 gaattcgagg ttttaaaagc agaagtagca gatttagccc aaacggacga agatgtgctg
    47461 acttatgccc tcttcccaag cgtagcaaaa ccgtttttaa caaccaaata ccaaactgat
    47521 gacgtcatta aagtgactgc ctttatcaaa gcataatagg ctatcttaat cagatagaaa
    47581 caaaaatatg gagatcaaat gacctattcc tttattgata tcttacaagt taccttagta
    47641 tccttgttct tagtgttaac ctgtttaaca gggattatgg gattaatgat gctaagtggt
    47701 aaattattgt cacaagaaaa aaaaactctc tctcaacaag cttccagcat tcctcaagag
    47761 caagaagctg acaagttgag tggagaagct ctcgaaactc ttttagccaa agacgaattg
    47821 gctagaattg ctgttatgac tagtcttgct tatgctagcc aagaagagtc aggaaaacgg
    47881 tttgaagtta ttgccgtgga aaggaaatcc taatgaaaag atatgaagtg actgtcaatg
    47941 gacaggttta tgaagtgagt ttacttgaac tagctgatgg agaaactgtt caagttagcc
    48001 ggccagcagc acctgctact gagaaagaaa tgaatgccaa cgctgctggc ggtggcctac
    48061 aggtaaaggc tccaatgtct ggaacagtct tgtctatctt tgctacagaa ggaaaagctg
    48121 ttaaaaaagg agaagctgtt ctggtcttag aggccatgaa aatggagaat gaaattctag
    48181 cacctgcaga tggtctggtt tcaaaaattc atgttgtggc taaccaaacg gtcgagtctg
    48241 aacaagtttt gatttcattc taggaggaaa ccatgctaga cgtactcaat caaatggtcc
    48301 aatcgtcagg attggctcat ctaactgtta ataatcttat catgatttgc ttggcctgtt
    48361 tctttttata ccttggtatc aaaaaggaat atgagcctta ccttatggta ccaatcgcct
    48421 ttgggatttt actcgttaat ttgcctatgg cgggattgat ggaccaccct gccaatggta
    48481 atcctggtgg ccttctttat tacctatata agggaactag cctagggatt tacccacctt
    48541 taatttttct ttgtttgggg gcatcaactg actttggtcc cttgattgcc aatcctaaaa
    48601 ccattttact aggaggcgca gcacaagttg ggattttctt agcctttttc cttgctatta
    48661 tgttaggcat gacacctcaa gaagcggctt ctgtcgggat tattggtggt gccgatggac
    48721 caacagctat ttatgtgacg acaaagttgg cgcctgattt actctctact atcgccctag
    48781 cagcttattc ttacatggct ctggtaccta ttattcaacc tcctatcatt aaactcttga
    48841 ctaccaaggc ggaacgccaa gtgaaaatga ctcaagcaag aactgtttca caaaaagaaa
    48901 aaatcatttt cccgattatg gtaacaatct ttgtcagcct tttggttcca agtgctacaa
    48961 ccttggttgg ctgtttgatg ctgggaaatc tggtcagaga aattaaaatt gttcctaaaa
    49021 ttgtagagaa tctccaacaa gtggttatgt tttgcattac tatcatttta ggattaaccg
    49081 ttggtgctaa ggccaatgga gatctctttt tatcagccac aaccttgaaa attattgccc
    49141 ttgggctaat cgcctttgct gctggtacag cagggggtgt cttgatgggg aaggtcatgt
    49201 actatttatc tggtaacaaa gtgaacccta tgataggagc agcaggtgtt tcagctgttc
    49261 cgatggcagc gcgagtggtc caaaaggtcg gacaagaaga agatccaagt aatttcttac
    49321 tcatgcacgc catgggaccc aatgtagctg gcgttattgg ctcagccatt gcttcaggtg
    49381 ccttgctggc cttctttggc taattgtgaa aaaggattag taaattaatc ttaataaatc
    49441 attatcagga gttggaagca atctagctcc ttttttagta gaaagctcga gtgataaact
    49501 attccaaaat aattataaaa aaagactgtc ctgattgtac ggactatatc aattgacttt
    49561 tatagtctag ctgaaatagc agtgcaaaac taagacactc gttttaaagt agtttttcta
    49621 aaaaagcaaa ataaaaggtc agagccaata aatctgccgc gcccccaggg cttaaatgct
    49681 gattaatgag gcattgattg taggaggaca aagccaatct taggtcagtt gttgataaat
    49741 cttgttgcag gagtagtcgc atatctgctt taacgccttt ccatgcttca atccctccac
    49801 gatgaatcag atttccatct tcaacaatag acatcaaata aacaagaaga cgaagctgac
    49861 tggtttcggg gtcattttga cttatcatct gacgaaagta gggcaaggca tggtctgtta
    49921 aggtcgtgaa tccctcgctt gcctcacccc gaggtccttt gatgccataa gttacaaaga
    49981 gttgctcccc ataagtgaac tcttttttag tgttcaaatg accaaggtct gtttgaatca
    50041 aatgtgccgt cataggtttt actaaacgac agatagctag agtatcttcc ttgctaaaac
    50101 accctaaatc agtcattaag tgaggtgttc ttgctagata ggccccagtt gcaccaagaa
    50161 gtaaagccat ggaaaaattc aggcctttat gagtgttaat tccctgagta gcacaaaaca
    50221 tggtttcctc ggccttttga cctagttgtc taagacggtt aaacagaaga agtggctctt
    50281 cttttgcata agcaaaacct gtttcgatat aagcctgaaa aaaaggagag agtgctatca
    50341 tactgtcgat aaaggtcata aaggacatgt catcatgggc accgttatca aatcgatcaa
    50401 ctaaaccagg ttttggagat agtgagactt cataaagcaa agcttttaag gccagttgac
    50461 taatacttgt tagaactgcc ttagtcattt tgctcaggcc tcatttcttt taagataaat
    50521 tcaagtgagc tattcaagtg ttcatgtgta atcaacgtaa tttgctcatg atctttgttc
    50581 ttcatacctc ggtaaatcat ccagtgttca gatagagctc gtttacggcg ttcaactgaa
    50641 gaaatcgaaa tttttctaaa gtagaccaaa taagcttgca attctgtcac aatttctttt
    50701 aagcggacca tttggctata gctgtaaatc aaattgttaa aggcattaaa attatccaaa
    50761 atacgattgg tgtcatcctc tgcgataaag gtttcacagt cttccaacaa gttatgcatg
    50821 actttaaaat cttcttctgt cattaaatgc atcgcttgca ctgttgcgag agtctctaga
    50881 gcttttcgaa tttcaaaaat ttcacaggca tccttgatac taactccttt gacaataatg
    50941 ccttttttag gaatgtgctc tacaaggtgt tcttcagaca ataatcccaa agcgtagcga
    51001 ataggtgtcc tgctaatatt aagcgcaatg gaaaactctt tttcattaat gcggcttcca
    51061 acaggaattt gtcgcaaaat aatggtcgtt ttaagagcgt tataaaaggc tattttcaaa
    51121 gggatatttc ttgataggtc aaggttttgt ttaacggctt cgataatagg attcatgtca
    51181 tctccttaat gctagtgtcc tcactttatt atacttaaat ttgtgaaaca ttccaatagg
    51241 actagatgag ttctgaaaaa ttaaagccat gctcacaaaa ggacatgact ttaatcatct
    51301 cataaggaat aaggtagtag tgttatcgtt ggtttattgt ggaatgtaaa gtggcatttg
    51361 ccccatggca ataatggtta ccacaaagat aacaaagatg ataagggcat atttagcagc
    51421 ctctttttgc cattccccca tgtcaagacc tgtcaagcga agaagaagat aaatgaaggc
    51481 aactaatgga ctaagtaagt ggaaggcttg tcccatgagg gaagcaagtg ccatagccat
    51541 gttactgaaa ccatattcag caccagcttc tgcaagaaca ggcaagatac catagtaaaa
    51601 accatcattg gagataaaga aggtaccagg tgcagaaact aaggcaataa caagacccca
    51661 gaaacctgcc agttgttttg gaataatggt tgcaaaactt tgtgcaagag cgctagccat
    51721 accagaacct tggaaaagac ccataaagat accagcagca aagactaaga taaccacttg
    51781 aaccgcatca ccagcattgt caccaatgcg ttttgattga tctttaagta ctgggtaatt
    51841 gaccatcaag gcgatacaag ttcccaccgc aaaaagaaga agcggtgcca tagcaataga
    51901 tttgttgaaa gagccagcaa ctaaccaagt gattaatcca atggttagga tagcattgaa
    51961 aacaaagttt ttaggacgac gaataaaaag ggtatctggg tcagtaatgt ctgtgagttg
    52021 acgcatgtct tcttcagaca agtcaataac accaagtctt gcacgttctt tacgccccat
    52081 gcttggagca acccaacaaa tcacataaag aagagataaa atcatacccg gtgcaagata
    52141 gccaagaatt tcaggaccga caccaagaac agacatcgca cgagcagtag ggccacccca
    52201 tggcagtaag ttcataatag tattttgaag aataatcaag acacctaggt tcatgatttt
    52261 catgtccaat tttttataga taggtaagaa agcagagcaa caaattaaag tagtggttgt
    52321 tccatcacca ttaagagata ctgcagcagc aacgacagct gttgcgataa gcaccttcat
    52381 tggatcacct ttagcaaagc gaatcatctt ttcagtaatc ggatcaaaca atcctgcatc
    52441 taacatgaca gagaagaaca aaatggcaaa tagcaacatg atacctgttt tagcagtatt
    52501 gttgatacca tacataacca ttggtccgat agctgttagg tctttagcaa ttccaccgtc
    52561 accaacaaag gcaacaaatt tggcatctgc attgaagtca gctgaaccag tcagtataac
    52621 agcaatcgtc atgattaatg gaatcatgac caaagcagta aaaggggtca tttttttctt
    52681 cattaccacg tacataaaga caataatcat ggcataagcc agcattgtta ataacatcat
    52741 tgttatctcc tttttcaagt tatgatttca gtatagatga aagcgcttat aaaataaata
    52801 cttctttgtg cagaaagaca caaaaaaaac aatttgaaaa ttaattttga aaaccatttt
    52861 tattacatca gatgacttta aattttctat aataatgatg aacctagtta gatcaagctt
    52921 ttcttgctat cagtatcttg atctcagttt ttcaacagtt acctaaaaat aaaataaaag
    52981 gtaactgttg aaaaacttta tgaaacattg aaagcgctct tagaaagaac acaaaaaagc
    53041 catctcaaaa aagattggta gtatataata aacttactag ttccctaaat aggtaaatgt
    53101 gaaaaagagg tagctcatgc agtttttaca aaaatggttt aaacactcta aaaaagagaa
    53161 gttgaaagaa tcctcgcccc ttagtacaga aatagaacct tctgaaaact gggaaaagat
    53221 tcccgcttat attcctgcag acaaaagtga ttacaaaaag gttactttaa ttaccagtgc
    53281 tattgctgct ggcgatagac ctaatagtca attcaaggtt aaacgcattc tcaagcgcaa
    53341 tcctgaggca atcactgttt ctttaattgc ttcaagtatc gctgcaggtg tttacccaga
    53401 aagtcagttt cgggtgacat ccatctattg caaaaggtag tcgttgaacg atactttaga
    53461 cgaactcatg acacaataac atataggaga aaaatgatgt tacgaaaatt taaaattacc
    53521 attgacggta aagaatatct tgtagaaatg gaagaaatcg gtgctcctgc ccaagcagct
    53581 gcccccgctc aaccaatatc cactccagta cctgtcccta ctgaagcaag cccacaagtg
    53641 gaggaagcgc aagcaccaca gccagtagct gcagcgggag cggatgccat tccatcacca
    53701 atgcctggaa ccatcttaaa agtcttagta gcagtgggag accaagtaac tgaaaatcag
    53761 ccactattga ttttagaagc catgaagatg gaaaatgaga ttgtggcctc atcagcagga
    53821 accattacag ctatccacgt cggtccaggt caagtggtca atcctggtga tggtctcatt
    53881 acaattggtt aatagtacta taactagaat aaatagacag aaaaggaagt gaatttgtgg
    53941 acactttaat cgcaggaata acctccatca ccattcctca aattgttatg atggtcatcg
    54001 gtgccctctt aatgtatcta ggaattaaaa aagaatacga accaacctta cttgtcccca
    54061 tgggacttgg aaccattctc gttaacttcc ctggttcagg agttttaacc caagtggtta
    54121 acggagtcga gcaagaaggg gtttttgagg ctctcttcaa ttttgggatt ggaacagaac
    54181 ttttcccact gttgattttc attggtattg gcgccatgat tgactttggt cccttgcttc
    54241 aaaacccatt catgctcttg tttggtgctg cagcgcaatt tgggattttc tttgttgttg
    54301 ttgttgctgt actggctggc tttgacatta aagaagcagc ttcaatcggc attatcggag
    54361 cagcagatgg accgacttct atctttgttg ccaaccaact ggccaaggat ttactgggtc
    54421 caattacggt tgcagcctat tcttacatgg ctctggttcc tattatccaa ccatttgcca
    54481 ttaaattagt gacaacgaaa aaagagcgcc gtatccgtat gacttacaaa gctgagaatg
    54541 tatctcaaat gactaaaatc ttattcccaa tcatcattac cttagtagca gggttcatcg
    54601 ccccaatttc tctaccttta gttggctttt tgatgttcgg taacttatta cgtgagtgcg
    54661 gtgtgctcga tcgcctgtca caaactgctc aaaatgaatt ggtaaacatt attagtatct
    54721 tgcttggatt gaccatctct attaaaatgc aggcagacct gttcttaaat gtacagacac
    54781 tcttaattat cgtctttggt ttacttgctt ttatcatgga ttctatcggt ggggtcatgt
    54841 ttgccaaatt tctcaatctc ttccgaaaag agaagattaa tccaatgatt ggcgctgcgg
    54901 gtatttcagc ttttccaatg tcaagtcgtg tcattcaaaa aatggcaaca gatgaagacc
    54961 cgcaaaactt tatcctcatg tatgctgtag gtgccaatgt ctctggccaa atcgcctctg
    55021 ttatcgcagg tggtttgttg ctagcttact ttagctaaga aaggaaggaa agcttatgac
    55081 aattaatatg gaccatttga ttagttcctt tgagctaatg gcgcttggta tggcaggtgt
    55141 ctttatcgtg ttaggaattc tctatcttgt cgcagagatc ctgatcaaac ttttcccagt
    55201 tagtaaataa caatatcatt taagaaaatc aaggaggtaa acgcaatgga tattaaacaa
    55261 actgccgttg ctggttcact tgaatcaagt gacctaatga ttacagtatc ccctaatgac
    55321 gagaaaacca ttacaataac cctagacagt agtgttgaaa aacaatttgg caatcacatt
    55381 cgtcaactca ttcatcaaac cctagtgaat ttgaaggtga cggctgctaa agtagaggct
    55441 gttgataaag gcgctttaga ttgcaccatt caagcgagaa ccatcgcagc tgttcatcgc
    55501 gcagctggtg ttgaccaata cgattggaag gagattgact catggaacgt ttaagaagaa
    55561 caatgatgtt tgtgccaggt gccaatgctg ctatgcttcg agatgctcct ttgtttggtg
    55621 ctgattcaat catgtttgac ttggaagatt ctgtttcact caaagaaaaa gacacttcta
    55681 gagctctcgt ccattttgcg ctaaaaactt ttgattattc gagcgttgaa acggttgttc
    55741 gtgtgaatgg tcttgattct tgtggggctt tagacatcga agctgttgtt ttggcaggtg
    55801 tcaacgtgat tcgtcttcca aaaacagaga ctgcacaaga tatcgttgat gtggaggctg
    55861 ttattgaacg tgtcgaacgt gagaacagca ttgaagttgg tcgcacacgt atgatggcag
    55921 ccattgaatc agccgaaggt gttctaaatg ctcgtgagat tgccaaagct tctaagcgct
    55981 tgattggtat tgctcttggg gcagaagact atgtcacgaa tatgaaaacg cgtcgttacc
    56041 cagatggtca agaattattc tttgctcgta gcatgatttt acatgctgct cgtgctgctg
    56101 gaattgctgc cattgatact gtttattctg atgtcaataa tacagaagga ttccaaaacg
    56161 aagttcgtat gatcaaacag ttaggatttg acggtaaatc ggtcatcaac cctcgccaaa
    56221 ttcctctggt caatgagatt tataccccaa ccgaaaaaga aattgaccat tccaaacaag
    56281 tcatctgggc aattcgtgaa gctgaaagca aaggctctgg cgttatttcc ttaaatggaa
    56341 aaatggttga taaaccaatc gttgaacgtg cagaatgtgt cattgcccta gcaacagcag
    56401 caggtgtttt atctgaggag gacatttaaa gatggtaaca aataaactcg gtagagatat
    56461 tcctcaacca tacgccgacc aatacggtgt ctttgaagga gaactcgcaa atatcaaaca
    56521 gtatgacgaa tcaagtcgcc gtattaaacc agttaagcct ggagattcta aattactagg
    56581 atctgttcgt gaagcgattg aaaaaacagg tttaacagat ggcatgacca tttctttcca
    56641 ccaccatttc cgtgaagggg atttcattat gaatatggtc ttggaggaaa ttgccaaaat
    56701 gggcattaaa aacctgtcta ttgccccaag ttccatcgct aatgtacatg agcctttgat
    56761 tgatcacatc aaaaatggtg tggtcactaa catcacttca tctggtcttc gtgacaaagt
    56821 aggggcagcc atctcagaag gactaatgga aaatcctgtg gttattcgct cccatggtgg
    56881 tcgcgctcgt gccattgcta gtggggatat ccatattgat gttgcctttc tgggcgcccc
    56941 aagttcagat gcttacggaa atgttaatgg gacaaaaggg aaagcaacct gtggttcttt
    57001 gggctatgcc atgattgatg ccaaatatgc ggatcaggtg gttatcttga cagataattt
    57061 ggttccttat cctaataccc caatcagcat tcctcaaaca gatgttgact atgtggtaac
    57121 agtggatgct atcggagatc ctcaaggaat cgccaaaggg gcaactcgtt ttacgaaaaa
    57181 tcctaaagaa ctcttaattg cagaatacgc cgctaaagta atcaccaact ctccttattt
    57241 taaagaagga ttctctttcc aaactggaac aggtggcgct tctttggcag taacccgttt
    57301 catgcgtgaa gctatgatta aagaaaatat caaagctagc tttgctcttg gtggtattac
    57361 caatgctatg gtggagttgc tcgaagaagg actggttgaa aaaattcttg atgtccaaga
    57421 ctttgatcac ccatcagctg tttctcttgg taagcatgct gaccattatg aaattgatgc
    57481 caacatgtat gcctcacctt tgagcaaggg tgctgttatc aatcaattag acacttgtat
    57541 tttatcagcc cttgaagtcg atactaactt caatgttaat gtgatgacag gatctgacgg
    57601 cgtgattcgt ggcgcttctg gaggacactg cgacactgcc tttgcggcta agatgagttt
    57661 ggttatttca ccacttatcc gcggacgcat cccaactttt gtagatgagg ttaatacggt
    57721 cattacacca ggaacaagtg tcgatgtggt cgtcacagaa gtgggaattg ccattaaccc
    57781 aaatcgtcaa gacttagtag accatttcaa atccctcaat gtgccacaat ttagtattga
    57841 ggagctaaaa gagaaggctt acgctatcgt tggcacacct gagcgtattc aatatggtga
    57901 taaggttgtt gctcttattg aataccgtga tggtagcctc atggatgtgg tttacaatgt
    57961 gtaaagacac ttatttttca ggcgaagcta tccaacttag tgatatgtta agagcccgcg
    58021 aagaaagagc tctgcgtcag ctgcatttat taaaggagta cccagaaggt agcttattat
    58081 cggtcaccat gaatatccct ggaccaatta aaacctctcc taaacttctt gaagtttttg
    58141 atatagtgat taaggccatt caaactgcct tagctgacga taagatttgt taccagttgc
    58201 gattactgcc tacaacgggt tatgagtatt acctcatcac aagtctacct agccgcgacc
    58261 tgaagttaaa aatgatagcc ttagagacag agttgccaat aggtcgtctc atggatttag
    58321 atgtcttggt cttgcaaaat gatctgcctc attcaattag cagaaccgta ttaggaggct
    58381 cccctaggca atgttttatc tgttctaaag aggccaaagt ctgcggtcgc ctacgtaagc
    58441 acagtgtcga ggagatgcag actgctattt caaaattact ccattcattt ttcaataaag
    58501 acaaccaatc atcgtcatca gataagacag gttgatgagg agaacaatta tgacgaaaat
    58561 ccgtataacg gaaacagttt tacgtgatgg tcaacaaagt cagattgcca cacgtatgac
    58621 aaccaaggaa atgattccta ttctcgaaac gctagacaat gctggttatc atgcccttga
    58681 aatgtgggga ggagcaacct ttgattcctg cctacgcttt ttaaatgaag acccttggga
    58741 acggctaaga gccatccgta aagcagtgaa aaagactaaa cttcagatgc tcttacgcgg
    58801 acaaaacctt cttggatatc gcaattatgc tgacgatgtg gtcagatcct tcgttcaaaa
    58861 atccattgaa aacgggattg atattgtccg tatcttcgat gctttaaatg accctcgcaa
    58921 cttgcaaaca gctgtttcag cgactaaaaa atttggaggg catgctcaag ttgccatttc
    58981 ttacacgaca agtccggtac ataccattga ctactttgtt gaattggcga aagcttacca
    59041 agctatcgga gcggactcca tttgtatcaa agacatggct ggtgtcttaa ctcctgaaat
    59101 aggttaccaa ttggtcaaat gtatcaagga gaatacaact attcctcttg aggttcatac
    59161 ccatgctacc agtggtattt cagaaatgac ttacttaaaa gtagcagaag caggagctga
    59221 tattattgat acggcgattt cctctttttc agggggaacc agtcagcctg ccacagagtc
    59281 aatggcgatt gccttgacgg atttaggctt tgacacaggc ttggatatgc aagaggtggc
    59341 caaagttgca gaatatttca acactattcg tgaccactat cgagaaatag ggattttaaa
    59401 tcctaaagtc aaagatactg agccaaaaac attgatttac caagttccag gtggcatgct
    59461 atcaaaccta ttgagccaat taaccgagca aggcctagct gataaatacg aagaagtctt
    59521 agcagaagta cctaaagtaa gggctgatct tgggtatccg ccactcgtaa cgccattatc
    59581 acaaatggtt ggaacacagg ccttgatgaa tatcatctca ggggaacgct acaaggtagt
    59641 tccaaatgaa atcaaagact atgttcgagg gctatacggt caatcaccag ccccattagc
    59701 agaaggtatc aaagagaaaa tcattggtga cgaagcagtc attgcttgca gaccagctga
    59761 cttaatcgag cctcaaatga tttatctacg tgacgagatt gctcaatacg ctcgttcaga
    59821 agaagacgtg ttaagctatg cgagtttccc acagcaagcc agagatttct tgggacgccg
    59881 tgaagatcct ttctatgatg ttccggttca agaagttact gtacaactgg acattcaaga
    59941 ctaacaggga atgactaatc ctcttaacca ttaatctcct tggtgaaacg catttgctgt
    60001 aagaacaata ccaaaaacct acctgatttt gataatcaga taggtttttt atcttagtaa
    60061 tgtttgacag atgaagtggc ttgtatcttt ttaataatgg gttgggcttc tagcgaacaa
    60121 aaataatcta aagacgtttt gggaaggagt tttgccagaa ggtcccaatc actatctttc
    60181 aatgcctgcc tagccgttga ggcactgata ggatcttgct gctgattgat agctttcctt
    60241 ggcaaaatat ctaggaggat accagcttgc tgcaactgct ctgccatgat ttcattgtaa
    60301 atagcagtta ctcggctggt tggctcttct ccaacgtatc tttttgtaat ctgtaaggtt
    60361 tgagcaatct ttagaaaaat agcagtatcc agcaaagctt ggcttttgat cacatcattg
    60421 tcttccgttt ggaaataagc tggaaaggtt gcctgactaa tcaaataagg acctgtttca
    60481 tgaaagataa tgttatcaag atgtttcaat ccttcttgaa tcaacatttt tcgtactgaa
    60541 aaaggaacca agctttggtc ctcactgacc ataaacagat gaacccaatc attttctctt
    60601 gcagctttct ctactaaaaa ttgatgccct aaggtaaagg ggttagcgtt gataacaata
    60661 gcagcgactt taccaggtgt ttgctcaggc ttattaagtg tcatcagata atcttgaaaa
    60721 ccagtttttt tattttccaa gaaactgatg tgattgtcga tatggacaat ttcagtaaaa
    60781 ccaagatctt tgaaaaaagc agcagaagag gtcttcgtat aaacaaaaag atgatagttg
    60841 ccaagggcat attcttcatc aatgagatga ctcacaatcc tattaagaaa tcctccacct
    60901 tgataggcac tggatacgca aagacagcgc aagctatttc caaagtaaga accggtagca
    60961 atcacatcat tttgcgcatt catgatggca caagtataat ctaaatgagc atccaaacga
    61021 ataccttctt gatgaagcag gttctttaca ctagccattg tcgttttatc tgaaggaaag
    61081 acttttgaaa tagtgtagta aggcatttct tctccgtatc tttaatttta ttgaatcata
    61141 acataactta gtaccaaaac aggctgatct atctaaaggc aactctgttt tttatcaacg
    61201 ccatttttta aaaggaaatc gaatgtgttt gacagactca aaagtatcag cgattttttg
    61261 attgcgttcc acagtccgca agttttcttg gtctaataag tcttgacttt tttccaaaac
    61321 atcaacagta atgtagtaga gtttgatcag gcttcctatc ttatatttac cagattttgg
    61381 agacatagca accacttcat tgagattact atgaagccat tttttatgag gcttagcagg
    61441 tatagtggct actacaaagc caagttgttc caaatgagct tgtgcctgat caacaggaag
    61501 attaatcaca tcatctatcg tgcgtagttg catctctttt tcatgttttt gttccatacg
    61561 tttttcgata attggtcgac tgttatcaat cgtttttcca ataatttcag tagtgtcagg
    61621 aacaattgac atcagtttcc caactactcc tagagctttt cttattctct ttggcatctt
    61681 ttatctcctc aagtcgtttc tttttattat aacaaaatgt ctaaaaatag tatgcgataa
    61741 accttgttct aaaaggttaa atagatcaat tcaaggaaaa aataggaggg gagccgacaa
    61801 aaaacacaaa gattctaaaa aagtcaagct attttagttt agcctttgtc aatcgtatca
    61861 gttcaaatag aaaatacaaa ttttgacaag aatttattta tgtaacaaac tgtgtttttg
    61921 attcttcagt ctatctaacg ataatgttat ctgattcttg ttttcaacca attgatgtta
    61981 aagaagctgt cttcatgatt ctctaatatt ccttcaattt tagctttata ttactctaag
    62041 ttatcagtaa tgacattaag tagtttaaca agaataatcc taaaagctac tttacaaaat
    62101 aacgtattat catactaaat aaaagtactg acatactaaa aacaggctta tctcatcttt
    62161 ttgatgagaa ccctactaga tttaatctat aaacatcaca aaaaagtcat tcaaagaagg
    62221 gacaaagtta gcagtaatat tcctttttct aagtggcttg agtagtttgg aaaacggcct
    62281 gacaccaaac tgtcacggtt aatagtagtc atctattaaa gttaatttaa aagctatttt
    62341 tatctttaat gttacataaa aacaattatg taacattaaa ggttatctaa agcatttttt
    62401 tgctcatcat tgacaatatg ggtataaaga tccgtgactt gagtagagga atggcctaat
    62461 tgatgactaa ctaacacctg agatttagta gcatcatata gtcttgtcgc tagcgtatga
    62521 cgcaatttgt gaggagtcac acgaatttta aaatcctcag agtacttgcc aaccatcttt
    62581 tctatactag aagcatccat tcgatttgga acgccacggt attctgttaa aaagaaagca
    62641 agatcctgtt tttcagcctt gtaacgtctc tgacgaacag ctaaataaga ctccaaataa
    62701 cctttcgcaa aacctgctac attgactgaa tcacgttttc cgcctttgcg aataacttcg
    62761 ataatcatca tatttagatt gacatctttt aaatcaagat tcactgcttc agacaaacga
    62821 acaccagaag caagtagtag agcaataata gccaaatccc tctccttatt tttacggaaa
    62881 gaagatttgg cacgattaga caatttttgc tcatattcct tatccacata atccaagaaa
    62941 gctagagttt catcacctaa aaacagtttc tgcttaatat tttccgctct ggaggccagg
    63001 gtttcttttt tcttttttgt tgacactttt ttcataacat tccgataaaa ataaggctcc
    63061 ccttggtcat tttcaacctc ttcagtcaag tacttgtaaa ggcttgataa ggcagacaag
    63121 gtccgattaa tagtggtttg agaaagcccc tctttggtgg aataggtgtt gagagaaggt
    63181 cgttcccgca aataaagcac aaaggcctct aaatccttct tggtaaggtg ctcaagcgtg
    63241 ctcaagtcaa tatcagcaat ctttggcgcc tgcgttaaat cagcatccat cagccaatca
    63301 aaaaagcgtt tgtattcttt taaatactca tataaggtgg taaagctgta tggaacagct
    63361 aatttggatt ggtaataatc taaaacatac caaggcatga cagccttgta ggtttcaatt
    63421 ttttctagta ataattcgcg tctcatatca tcataattcc ttaacaataa caattttttc
    63481 aaaaatgaat tttcgcaaat tgtctcatgt attttatgcc attcattctc tacaagagca
    63541 gtatatcaca cctataaata tttttcaaga aaattacagt ttttcggaaa gatgtcacga
    63601 gacaaatctc tttttttaca gata
//
LOCUS       DATWVB010000007        61438 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.007, whole genome shotgun sequence.
ACCESSION   DATWVB010000007 DATWVB010000000
VERSION     DATWVB010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61438
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.007"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            79..1443
                     /gene="ftsA"
                     /locus_tag="VCX65_000475"
     CDS             79..1443
                     /gene="ftsA"
                     /locus_tag="VCX65_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEP5052959.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            1467..2786
                     /gene="ftsZ"
                     /locus_tag="VCX65_000476"
     CDS             1467..2786
                     /gene="ftsZ"
                     /locus_tag="VCX65_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEP5052960.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            2789..3460
                     /locus_tag="VCX65_000477"
     CDS             2789..3460
                     /locus_tag="VCX65_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEP5052961.1"
                     /translation="MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQ
                     LIEAGIEHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEKIQLVGLMTMA
                     PANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            3472..4128
                     /locus_tag="VCX65_000478"
     CDS             3472..4128
                     /locus_tag="VCX65_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEP5052962.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSGIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            4133..4387
                     /locus_tag="VCX65_000479"
     CDS             4133..4387
                     /locus_tag="VCX65_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEP5052963.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            4387..5178
                     /locus_tag="VCX65_000480"
     CDS             4387..5178
                     /locus_tag="VCX65_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEP5052964.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVGDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRLA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGKQKITLSKMIHK"
     gene            5188..5946
                     /locus_tag="VCX65_000481"
     CDS             5188..5946
                     /locus_tag="VCX65_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEP5052965.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            6219..9020
                     /locus_tag="VCX65_000482"
     CDS             6219..9020
                     /locus_tag="VCX65_000482"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEP5052966.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRDDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMTENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNTKENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEHESEAFVQLAEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGIAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESDK"
     gene            complement(9285..9587)
                     /locus_tag="VCX65_000483"
     CDS             complement(9285..9587)
                     /locus_tag="VCX65_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEP5052967.1"
                     /translation="MRLINTTSSHPELIRNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(9638..10093)
                     /locus_tag="VCX65_000484"
     CDS             complement(9638..10093)
                     /locus_tag="VCX65_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEP5052968.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLSWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(10221..12503)
                     /locus_tag="VCX65_000485"
     CDS             complement(10221..12503)
                     /locus_tag="VCX65_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEP5052969.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGDSFLNEESLD"
     gene            12801..13031
                     /locus_tag="VCX65_000486"
     CDS             12801..13031
                     /locus_tag="VCX65_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEP5052970.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            13158..13844
                     /locus_tag="VCX65_000487"
     CDS             13158..13844
                     /locus_tag="VCX65_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP5052971.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSAFLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMAQGGNH"
     gene            13844..14578
                     /locus_tag="VCX65_000488"
     CDS             13844..14578
                     /locus_tag="VCX65_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP5052972.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            14727..16136
                     /locus_tag="VCX65_000489"
     CDS             14727..16136
                     /locus_tag="VCX65_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HEP5052973.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCESIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVT
                     QGKRFDPKGEFIKAYLPQLEHVPEKYLHEPWKMPKYLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKAKIE"
     gene            16314..18008
                     /locus_tag="VCX65_000490"
     CDS             16314..18008
                     /locus_tag="VCX65_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEP5052974.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYEEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            18216..19070
                     /locus_tag="VCX65_000491"
     CDS             18216..19070
                     /locus_tag="VCX65_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEP5052975.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            19223..20563
                     /locus_tag="VCX65_000492"
     CDS             19223..20563
                     /locus_tag="VCX65_000492"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEP5052976.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHSLANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDASRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            20541..20756
                     /locus_tag="VCX65_000493"
     CDS             20541..20756
                     /locus_tag="VCX65_000493"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEP5052977.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            20756..21628
                     /locus_tag="VCX65_000494"
     CDS             20756..21628
                     /locus_tag="VCX65_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEP5052978.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            21621..22448
                     /locus_tag="VCX65_000495"
     CDS             21621..22448
                     /locus_tag="VCX65_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEP5052979.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVLASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQEVVAKAHKEFEKHEKE"
     gene            22435..22905
                     /locus_tag="VCX65_000496"
     CDS             22435..22905
                     /locus_tag="VCX65_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEP5052980.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            22927..24588
                     /gene="recN"
                     /locus_tag="VCX65_000497"
     CDS             22927..24588
                     /gene="recN"
                     /locus_tag="VCX65_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEP5052981.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIIKEY
                     QLLTGDDLSSGDLESELKALEKQLVAAAANLSERRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            24760..25701
                     /locus_tag="VCX65_000498"
     CDS             24760..25701
                     /locus_tag="VCX65_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP5052982.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFISQNETDKMFENLTDDRLLDEL
                     DELDELDELDELDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPHLR
                     SLSDTALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAH
                     YEDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYNRKLGMAVAK
                     RKIALPQTGEEFSYYPALLGLMILGLTPIMIPKKINN"
     gene            25917..26768
                     /locus_tag="VCX65_000499"
     CDS             25917..26768
                     /locus_tag="VCX65_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP5052983.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            26761..27603
                     /locus_tag="VCX65_000500"
     CDS             26761..27603
                     /locus_tag="VCX65_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEP5052984.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLTKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            27581..28168
                     /locus_tag="VCX65_000501"
     CDS             27581..28168
                     /locus_tag="VCX65_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEP5052985.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            28267..28542
                     /locus_tag="VCX65_000502"
     CDS             28267..28542
                     /locus_tag="VCX65_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEP5052986.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            28896..30758
                     /gene="cadA"
                     /locus_tag="VCX65_000503"
     CDS             28896..30758
                     /gene="cadA"
                     /locus_tag="VCX65_000503"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEP5052987.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITA
                     FLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYALLDDIKI
                     ESKRAIKSLHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     gene            complement(31058..31993)
                     /locus_tag="VCX65_000504"
     CDS             complement(31058..31993)
                     /locus_tag="VCX65_000504"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEP5052988.1"
                     /translation="MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIEDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            32232..32927
                     /locus_tag="VCX65_000505"
     CDS             32232..32927
                     /locus_tag="VCX65_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEP5052989.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            33034..33555
                     /locus_tag="VCX65_000506"
     CDS             33034..33555
                     /locus_tag="VCX65_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEP5052990.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            33716..34258
                     /locus_tag="VCX65_000507"
     CDS             33716..34258
                     /locus_tag="VCX65_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5052991.1"
                     /translation="MTKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            34382..35161
                     /locus_tag="VCX65_000508"
     CDS             34382..35161
                     /locus_tag="VCX65_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEP5052992.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFATNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            35959..36555
                     /gene="recR"
                     /locus_tag="VCX65_000509"
     CDS             35959..36555
                     /gene="recR"
                     /locus_tag="VCX65_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEP5052993.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            36656..37702
                     /locus_tag="VCX65_000510"
     CDS             36656..37702
                     /locus_tag="VCX65_000510"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEP5052994.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEMFDQRESHLI"
     gene            37901..39292
                     /locus_tag="VCX65_000511"
     CDS             37901..39292
                     /locus_tag="VCX65_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEP5052995.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVAAFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAP
                     GDPIIDPYLPENQMVIRFGNQQEIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVTDEDIIAALQTVTLTGNRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
                     RLVTDKNCDSYQP"
     gene            39372..40067
                     /locus_tag="VCX65_000512"
     CDS             39372..40067
                     /locus_tag="VCX65_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEP5052996.1"
                     /translation="MDFFAIDPIGLPHTSLIFYLSSLLIALLLVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYLGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLAFAFSKEK"
     gene            40315..41859
                     /locus_tag="VCX65_000513"
     CDS             40315..41859
                     /locus_tag="VCX65_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEP5052997.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNVFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            42166..43785
                     /locus_tag="VCX65_000514"
     CDS             42166..43785
                     /locus_tag="VCX65_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP5052998.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            43912..45912
                     /locus_tag="VCX65_000515"
     CDS             43912..45912
                     /locus_tag="VCX65_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEP5052999.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKISPWL
                     IIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLISEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYL
                     IKKGTRPILAHLAMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKR
                     PKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVTNARQLSNFERFIMQTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA"
     gene            complement(45936..46214)
                     /locus_tag="VCX65_000516"
     CDS             complement(45936..46214)
                     /locus_tag="VCX65_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEP5053000.1"
                     /translation="MTTKKAYMYVLECADKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(46204..47058)
                     /locus_tag="VCX65_000517"
     CDS             complement(46204..47058)
                     /locus_tag="VCX65_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEP5053001.1"
                     /translation="MKADFSKVKITLQTFTSSLFYVKITGMIKAILKEGERIDQLFSS
                     DVGIIQNKDVFSYSIDSVLLSRFPKMPSKGLIVDLCSGNGAVGLFASTRTKAAIVEVE
                     LQERLADMGQRSIQLNQLEDQVTMICDDLKNLLNHVPRSGVDLMLCNPPYFKSHESSK
                     KNVSEHYLLARHEVTTNLEEICQVARHALKSNGRLAMVHRPDRFLEIIDSLRANGLAP
                     KRVQFVYPKLGKSANMLLIEAIKDGSIEGMTILPPLVVHKENGEYTDHIFEIYFGAAS
                     KGKPNHDH"
     gene            47098..47838
                     /locus_tag="VCX65_000518"
     CDS             47098..47838
                     /locus_tag="VCX65_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEP5053002.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKLAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRMDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTILFSYIASFVWNPDKHRH"
     gene            48038..48700
                     /locus_tag="VCX65_000519"
     CDS             48038..48700
                     /locus_tag="VCX65_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEP5053003.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            48681..50923
                     /locus_tag="VCX65_000520"
                     /pseudo
     CDS             48681..50923
                     /locus_tag="VCX65_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
     gene            50994..52034
                     /locus_tag="VCX65_000521"
     CDS             50994..52034
                     /locus_tag="VCX65_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEP5053004.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMEQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSHQ
                     LGLGFESGAFEQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKVDVARDLIHDLRLSGEDDIKLIAIMLGQFRLYLQLAILAKEGKSEQQL
                     VTSLSEILDRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            52131..52736
                     /locus_tag="VCX65_000522"
     CDS             52131..52736
                     /locus_tag="VCX65_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEP5053005.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSELYQAAK"
     gene            52903..53129
                     /locus_tag="VCX65_000523"
                     /pseudo
     CDS             52903..53129
                     /locus_tag="VCX65_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            53114..53362
                     /locus_tag="VCX65_000524"
     CDS             53114..53362
                     /locus_tag="VCX65_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053006.1"
                     /translation="MDADLAQMDALGLYYDDNHLSLVNTVKVYLKEFGIGESQIAFSY
                     KDLNSGRTAAMNDHQPMIAGSTYKLPLNMLVVDKANYP"
     gene            53359..53949
                     /locus_tag="VCX65_000525"
     CDS             53359..53949
                     /locus_tag="VCX65_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEP5053007.1"
                     /translation="MTERFDITETDYEYDQEHHAYVAQFNGAMSIPDMQEYSLVYSEN
                     TPAYALAERLGGMNKAYQLFDRYGKVSGAITTIDRNGNKITTAYYLQGLDYLWQHQDK
                     YKDILYYIGESFPDLYYKTYLPHVKVYQKPGYVREALNVGAIVCEESPYLITLYSSGL
                     GGATQASEEVNGLGYVQLVQLTYVINEWHRVNHNMI"
     gene            complement(54063..55283)
                     /locus_tag="VCX65_000526"
     CDS             complement(54063..55283)
                     /locus_tag="VCX65_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEP5053008.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQNLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSTLIQAYYVNLEHIPYSRSNRKIHQLRYLISTQQTEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(55290..56318)
                     /gene="queA"
                     /locus_tag="VCX65_000527"
     CDS             complement(55290..56318)
                     /gene="queA"
                     /locus_tag="VCX65_000527"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEP5053009.1"
                     /translation="MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGGKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            56520..57224
                     /gene="nagB"
                     /locus_tag="VCX65_000528"
     CDS             56520..57224
                     /gene="nagB"
                     /locus_tag="VCX65_000528"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEP5053010.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDI
                     EAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIKANSRF
                     FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKH
                     DHVIVIVDEAAASQLD"
     gene            57343..58059
                     /locus_tag="VCX65_000529"
     CDS             57343..58059
                     /locus_tag="VCX65_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEP5053011.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPIHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTASERQLIKTYLD"
     gene            58354..59316
                     /locus_tag="VCX65_000530"
     CDS             58354..59316
                     /locus_tag="VCX65_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEP5053012.1"
                     /translation="MTKILTALDGKNQLISLVTQPISTKPPFCCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            59329..61134
                     /gene="pepF"
                     /locus_tag="VCX65_000531"
     CDS             59329..61134
                     /gene="pepF"
                     /locus_tag="VCX65_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEP5053013.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFS
                     GHLLDSSANLLTITDTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSIRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
BASE COUNT        18978 a        10615 c        12889 g        18956 t
ORIGIN      
        1 ataatatttt ctgaatgatt ctgtttttta gcagttttta gaatagcaaa agtttggaaa
       61 gtaagtgagg tcaagtgaat ggctagaaat ggctttttta ctggtttgga cattggaaca
      121 agctcgataa aagttttagt agcagaattt atttctggtg agatgaacgt cattggtgtt
      181 agtaatgttc caagtaccgg cgtaaaagat ggcataataa tcgatataga ggcagctgcg
      241 actgccatca aaactgcggt agaacaagca gaagaaaaag cagggatgac aattgaaaag
      301 gttaatgttg ggctaccggc aaaccttctt caaattgaac caacacaagg aatgattcct
      361 gtcccaagtg agtctaaaga gataaaagat gaggatgttg atagcgttgt taaatcggct
      421 ttaacaaaaa gtatcacacc agaacgagag gttatctctt tagttccaga agagttcatt
      481 gtggatggct ttcagggcat tcgagatcca cgtggtatga tggggattag attagagatg
      541 cgcgggctta tttatactgg accaagcacc attttacata atctgcgtaa aacggtagaa
      601 agagcaggca ttaaagttga aaacatcatt atttctccgt tagctatggc taaaaccatt
      661 ttaaacgaag gtgagcgcga gtttggagct actgtaattg atatgggagg tggacagaca
      721 actgtcgctt ctatgcgagc acaagaattg cagtatacca atatatatgc tgaaggcggc
      781 gaatacatta ctaaagatat atcaaaagta ttaaaaacgt ctttggctat tgcagaagca
      841 cttaagttta attttggtca agcggagata tcagaagcta gtataactga aacagtaaaa
      901 gttgatgtgg taggtagtga agagcctgtt gaggtaactg aacgttattt atctgaaatt
      961 atttcagcgc gtattcgtca tattttagat cgtgtgaagc aagatttgga aagaggtcgt
     1021 ttactagact taccaggagg cattgttttg attggtggcg gtgcaatcat gcctggagtg
     1081 gtagaaattg cacaagaaat ctttggagta actgtaaagc tccatgttcc aaatcaagtc
     1141 ggtattagaa atccaatgtt ttcaaacgtt atcagtttgg tagaatatgt tggtatgatg
     1201 tctgaagtag acgttttagc acaaactgca gtttcaggag aagaactttt gcgacgcaag
     1261 cctatcgatt tcagtggtca agaatcttat ttaccagatt atgatgattc aagaagacca
     1321 gaatcgacca ttggctatga acaacaagcg tcacaaacag catatgattc acaagttccg
     1381 agtgatccta aacaaaaaat ttcagaacgt gttcgtggca tatttgggag tatgtttgat
     1441 taaaagtaat aaagtgagga gataaaatgg cgttttcatt tgatactgca tcaattcaag
     1501 gtgcaattat aaaagtaatt ggagtcggcg gaggtggcgg aaatgccatt aatcgtatga
     1561 ttgatgaagg tgttgctggt gtcgagttca tcgcagcaaa tacagacatt caggcattaa
     1621 gctcatcaaa agctgaaacg gttattcaac taggccctaa attaactcgt ggacttggtg
     1681 ctggaggaca acctgaagta ggacgtaaag ctgctgaaga aagcgaagaa attttaacag
     1741 aagctcttac aggagcggat atggtattta ttactgccgg tatgggtggt ggctctggga
     1801 caggggctgc accggttatt gctcgtatcg ctaagagttt gggagccttg acagtagctg
     1861 ttgttactcg cccgtttggt tttgaaggta acaaacgtgg taattttgct attgaaggta
     1921 tcgaagaact ccgtgaacaa gttgatactt tgttaattat ttcaaataat aaccttcttg
     1981 agattgttga taaaaagaca cctttattag aagcacttag tgaagctgat aatgttttac
     2041 gtcagggagt tcaagggata accgacttaa ttactagtcc tggccttatc aatctcgatt
     2101 ttgccgacgt gaaaacagtt atggcaaata aagggaatgc cttaatgggg attgggattg
     2161 gttctggaga agagcgcatt gttgaggcgg cgcgtaaggc aatctattca cccctattag
     2221 aaacgactat tgatggtgca caagacgtta ttgtgaacgt tacaggaggt ctcgacatga
     2281 cactcacaga agctgaagaa gcctctgaaa ttgttgggca agctgctggt caaggcgtta
     2341 acatttggtt aggaacatct attgatgata ctatgaaaga tgacatccgt gtgactgttg
     2401 tagcaactgg agtgcgccaa gaaaaagccg aacaagtttc aggttttcgt cagcctagga
     2461 cttttaccca aaccaacgcg cagcaagtag cgggtgcaca atatgcatca gatcaagcaa
     2521 aacagtcggt tcaaccaggg tttgatcgtc gctcaaattt tgattttgac atgggggagt
     2581 ctcgcgagat accaagtgca caaaaggtaa tttctaatca taatcaaaat caaggttctg
     2641 cttttggaaa ttgggatttg agacgtgata atatttctcg tccaacagaa ggtgaattgg
     2701 ataaccatct taatatgtca acgttctcag ctaacgatga cagtgatgat gaattagaaa
     2761 cgcctccatt ctttaaaaac cgttaataat ggatttactg acaaataaaa agaaaatttt
     2821 tgagactatc cgcttatcta cagaggcagc aaataggact aatgatagtg tttcagttat
     2881 tgctgtaaca aaatatgtgg atagtacaat tgcaggtcag cttatcgaag caggaattga
     2941 gcacattgcc gaaaaccgtg ttgataaatt tcttgaaaag tatgatgcgt taaagtatat
     3001 gccagtaaag tggcatttaa tcggtacctt acaacgtcgt aaagtcaagg aagttatcaa
     3061 ttatgttgat tattttcacg ctctagattc tgtgagatta gctttggaaa tcaacaagag
     3121 agctgaccat cctgtgaagt gttttctaca agttaatatt tctaaagaag agagtaaaca
     3181 tggttttaac atttctgaga ttgatgaagc gattgaagaa ataggtaaga tggagaagat
     3241 acagttagtt ggtttaatga ctatggcacc agcaaatgcc agtaaagaaa gtattataac
     3301 tatttttcga caagcaaatc aattaagaaa aaacttgcag ttaaaaaaaa gaaagaatat
     3361 gccttttaca gaattgagca tgggcatgag taacgattat ccaattgcta ttcaagaagg
     3421 ctcaactttt attcggattg gtagagcttt ctttcactaa tggagaataa gatggctttt
     3481 aaagatacat ttaacaagat gatttcttat tttgacacgg atgaggttaa cgaagttgaa
     3541 gaagatgttg cagcatcaac tgataacgtt attccaagat cacaacaatc agtcagagca
     3601 agtagtcatc caaaacaaga acctagaaac aatcacgtac aacaagatca tcaggcgaga
     3661 tcccaagaac agacaaggtc acaaatgcat ccaaaacatg gtacttctga acgctattat
     3721 cagcagtctc agccaaaaga aggccatgaa atggttgaca gaagaaaacg gatgagcact
     3781 tctggtattg caaatcgccg tgagcagtat caacaatcaa cttgttcaga tcagacaact
     3841 attgccttaa aatatcctcg taaatatgag gatgctcaag aaattgtgga tcttttaata
     3901 gttaatgaat gcgttttgat tgattttcag tttatgctag atgctcaggc tagacggtgt
     3961 ttagatttta ttgatggtgc tagtaaagtg ctctatggta gcttacaaaa ggtcggctct
     4021 tcaatgtact tactggctcc gtcaaatgta tccgtcaata tagaagaaat gactatccca
     4081 catactacac aagatattgg ctttgatttt gatatgaaaa ggcggtaaat aaatgatatt
     4141 aatactatct attcttcttc gtctgatcaa agtttacact tatttattga ttgcttacgc
     4201 attaatgtca tggtttcctg gggcatatga ttcaaaaatt gggcgtttga ttagtggtat
     4261 cgttgaacca attttaaaac cttttagagc atttaattta caatttgccg gtcttgactt
     4321 cactattttt gtcgtcatta ttagtttgaa ttttttagct caagttttgg tccgtgtgtt
     4381 tatttaatgg ttagtcatag taagatttat cagcattttc accaagaaga atatcctttt
     4441 attgatagaa tgtctgatat gattaataga gttggagatt actatctttt agaagttact
     4501 gagtttttaa atcctagaga agtgatgatt ttaaaaagtt tgattgcttt aacagatcta
     4561 aaaatgttcg tatcaacaga ttactaccca agcgaatatg gtcgtgtcat tattgcacct
     4621 ggttactatg acttagaaca aagtgatttt caaatagctt tagtagagat aagttatcag
     4681 gcaaagttta atcagttgac acatagtcaa attttaggaa ctttaattaa tgaattagga
     4741 gtaaagcgaa atttatttgg agatgttttt gttgaaatgg gatatgccca gctcatgatt
     4801 aagcgggagt tattggatta ttttttagga acaattacta aaatagctaa aactagtgtg
     4861 aaattaagag aagttaactt tgatcagtta attaggtcta ttgataacag ccagaccctg
     4921 gatattctag tttctagttt tcgattagat ggtgtagttg ctactatctt aaaaaaatct
     4981 cgaacgcaag ttatagcatt aattgaagca aataagatta aggtaaacta tcgactcgct
     5041 aataaagctt cagataatct agtcataggg gatatggtga gtatcagagg tcacgggcgt
     5101 tttactcttt tagcagataa tggagtgacc aaacatggca aacaaaaaat aacactaagt
     5161 aaaatgatac ataaataagg agatacaatg gcacttacaa cgctagaaat taaagataaa
     5221 acttttaaga caaaattccg aggatactgt gaagaagaag tcaatgaatt ccttgatatt
     5281 gttgttgatg attacgaagc tcttgtacgt aaaaatcgtg ataacgaagc aagaattaaa
     5341 gatcttgaag aaaaattatc ttactttgat gaaatgaaag agtcacttag ccagtctgta
     5401 atcttagctc aagaaacagc tgaaaaagtg aaagcaacgg ctaatgcgga agcaacaaac
     5461 ttggttagta aagcgactta tgatgctcag catttattag atgaatctaa agctaaagcc
     5521 aatcaaatgt tgcgtgatgc aactgatgag gctaagcgag ttgcgattga aacagaagaa
     5581 ctaaagcgtc aaacacgtgt gttccaccaa cgtttaatct catctattga gtcacaatta
     5641 agcttatcaa attcacctga atgggatgaa ctgctacaac cgactgcaat ctatcttcaa
     5701 aattctgacg atgcttttaa ggaagtcgtg aagaccgttc ttaatgaaga cattcctgaa
     5761 tctgatgata gtgcctcttt tgatgcaaca cgtcagttta ctccagaaga gttagaagaa
     5821 ttgcaacgtc gtgttgatga aagcaataag gagttagagg cttaccaact tgactctcaa
     5881 tctgattcta cgactgagcc agaggtaaat ctcagtgaaa cacaaacgtt taaattaaat
     5941 atctaaataa agaaaaacaa gatgatttgc ttataatcac agcaagcggg agatgatgag
     6001 agtctcgtat tccctaagta ttatcattat cattttctaa aattttcgct gaactacagt
     6061 aagcgaggag gtttgttcac cttacgagca aagagggagc ggtaagtctt atgatatatt
     6121 atcgctctga actaaggtgg taccacgagc tttcgtcctt tttgagacga ggcttttttc
     6181 gttatagtcg caagtttgtt taaaaggagt ttgaaataat gaaattaaaa gagacactta
     6241 atctaggaaa aacagccttt ccaatgcgcg caggtcttcc taataaagag ccacaatggc
     6301 aagcagcttg ggaacaagca gagctttaca aaaaacgtca agaattgaat gcaggtaagc
     6361 ctgcctttca tcttcatgat ggacctccat acgctaacgg caatattcac gttgggcatg
     6421 cccttaataa aatttcaaaa gatatcattg tgcgttctaa gtccatgtct ggctttcaag
     6481 cgccttatgt acctggttgg gacacacacg gccttccaat cgaacaagtc ttggctaagc
     6541 aaggaatcaa acgtaaggag atggatttag cagaatacct tgagatgtgt cgtcaatacg
     6601 ctttaagtca ggttgataaa cagcgagatg atttcaaacg gttaggtgtt tcggcagact
     6661 gggaaaatcc ttatgtcact ttggacccac agtttgaagc tgatcaaatt cgtgtttttg
     6721 gagcgatggc tgaaaaaggt tacatctatc gtggtgctaa acctgtttat tggtcatggt
     6781 cttcagaatc ggccttggca gaagctgaaa ttgaatacca tgacatcgat tcaacctctt
     6841 tatactacgc caataaagtt aaagatggta aaggtatcct tgatactaat acgtatatcg
     6901 ttgtttggac aacaacacca tttacggtta cagcatcacg cggtttgact gttggtcctg
     6961 atatggatta tcttgtggtg aaacctgctg gttcagaccg tcaatatgtt gtggcagaag
     7021 gtcttttgga tagccttgct ggaaaatttg gctgggaatc ttttgaaact ttagctagcc
     7081 ataaaggagc tgatttagag tacattgtga cagaacaccc atgggatact gacgtagaag
     7141 aattggttat ccttggtgac catgttaccc ttgagtcagg gacagggatt gtccacacag
     7201 caccaggttt tggtgaggat gactacaatg ttgggacaaa atataaactg gaagttgctg
     7261 tgactgttga tgaacgtggc ctaatgacgg aaaatgcagg tccagatttc cacggacaat
     7321 tttataacaa ggtaacgccg attgtcattg ataaacttgg tgatctttta ttggcacaag
     7381 aagtgatcaa tcactcttac ccatttgact ggcggacgaa aaaaccaatc atctggcgtg
     7441 ctgtaccgca atggtttgct tctgtttctg atttccgtca agatattttg gatgaaattg
     7501 aaaaaacaac ctttcatcca tcatggggtg aaacacgcct ttacaatatg attcgtgatc
     7561 gtggcgactg ggttatttct cgtcaacgtg cttggggagt tccgcttcct atcttctatg
     7621 ccgaagatgg cacagctatt atgactaaag aagtgacaga tcatgtggct gatttgttcc
     7681 aagaaaatgg atcaatcatt tggtggcaaa aagaagctaa agacctatta ccagagggct
     7741 tcactcatcc agggtcacca aatggcgagt ttacaaaaga aactgatatc atggacgttt
     7801 ggtttgactc tggttcttct tggaatggag tcatgaatac taaagaaaat ctttcctatc
     7861 cagcggatct ctacttagaa ggctctgacc agtatcgtgg ttggttcaat tcatccttaa
     7921 ttacatctgt ggctgttaat gggcatgctc catataaggc tattttatcg caaggctttg
     7981 ttcttgatgg taagggcgaa aaaatgtcta aatcaaaagg caatatcatt tctcctaatg
     8041 atgtggctaa acaatatggt gcagatattc ttcgactttg ggtagcttct gtggataccg
     8101 ataatgatgt ccgtgtttct atggagatcc ttggtcaagt ctctgaaact taccgtaaaa
     8161 tccgtaacac ccttcgcttc ttgattgcta atacatctga tttcaaccct gctacggata
     8221 cagtagctta tgcagattta ggagctgttg ataagtacat gacaattgtc tttaatcagt
     8281 tggtagcaac gattactgac gcttatgagc gttatgactt tatggctatt tacaaagcag
     8341 tggtgaactt tgttacggtt gatttatcag ccttctatct tgattttgct aaagacgttg
     8401 tctatattga agctgccaat agcttagaac gtcgtcgcat gcagacagtc ttctatgata
     8461 tcttggttaa gattaccaag ttattgacgc caatcttgcc tcacactact gaagaaatct
     8521 ggtcttatct agagcatgag tcagaagcat ttgttcaatt ggcagaaatg cctgtggcag
     8581 aaactttctc agctcaagag gatattttag aagcttggtc tgctttcatg actttgcgta
     8641 cccaagctca aaaagctttg gaagaagcgc gaaatgctaa gattatcggt aaatcattgg
     8701 aagcccattt gaccatctac gctagcgaag aagtgaaaac cttattgact gctttagaca
     8761 gcgatattgc tttgcttttg atcgtgtctc aattaaccat tgctgacttg gcagatgcgc
     8821 ctgcggatgc agtggcattt gaaggtattg cctttatggt agaacatgcc ataggtgaag
     8881 tttgtgagcg ttcacgccgc atcgacccaa ctactcgcat gcgttcttac aatgcatttg
     8941 tctgtgatca cagcgctaaa atcattgaag aaaatttccc agaagctgtg gctgaagggt
     9001 ttgaagagag tgacaaataa gtcttatcaa gacttgaagt gacactgagt aagaagacaa
     9061 ccatcgggtc ttagggcctg atggtttttt agtagagctg attacgtcca ttagccagct
     9121 ttaacgagag acaaagtagg agaaatttag agtacttttt taatttcttt taagaaaatt
     9181 gctggcttca tataaggact attaagatag agttcacctt tcgctaataa aaaaacttag
     9241 ctcttttaga agggctaagt tttgtctgaa tagctggctg ctgtttatac agaagtttga
     9301 aatgaaattt caataaggtt attcgtgtga agtgtttttg attgtccagg aataacaatt
     9361 ttaggatcaa ttttacgttt taaaaaaaat tcgcgaatga tatcaagttc atcctccttg
     9421 atggcacggt atttatttga aataagtagt tcgtaatgtt ttggtgcttg ggtaaaaatg
     9481 acatctgtat ttcctgctga gtatacttcg actaaatagg catcggtgtt ttttagctga
     9541 tttctgatga gttctgggtg actgctagtg gtattgatga gtctcataaa tgtcctcctt
     9601 agtattcctg tacctattat agcactaatt taaagcctta gttagtagaa tgatgctttt
     9661 tttgccattc cttgactccc cattgatggc tctctcgttt taatttagca attgcctcga
     9721 taggagaaaa ccaacttaag ttattaaaat cttctaaggg cttagaaacg gcttgaaatg
     9781 cggttacttc ataaagatag gcaggatggt agaagtgggt atcacgatgg cgagagtaga
     9841 aatattcatc agcctgaccg taatatgaac caatagtagc agaaaaacca agttcttcaa
     9901 tcagttcacg ctctagggcc tgaagctgac cttcacctgc ttcaatttca ccaccaggta
     9961 aaaaccagga accattagga gcttgaacaa gaataatttt tgtttgttcg tgattgggaa
    10021 tgatagcata gacaccgtaa cgtgtgacat agtctttatg tgcattttta tgtccaaatg
    10081 ttggaatcat cattttattt acctttcctt tttcttcatt atactaaatt tttgctaatt
    10141 attcttatca atttgtttag tttaataaaa aattgataga aaaagagaga gtctccttat
    10201 agaaactctc ttagctaacg ttaatctaga gactcttcgt taagaaaaga atctccctct
    10261 ttaacagctt taatcgtgat gttttcactg tttgtcatca gtgcacgtaa ctgtttttca
    10321 gttgggtgtt ctaaataata gtctgtaatg gcatcttcga tataatcttg gatagtacga
    10381 cggagcggcc gagcgcccat tttaggatca tagcctaaat ctactaattt ttctttgacc
    10441 ttttgtgtca catcaagatg aatcccatta tagcctaagc gctcattaac atcttccagc
    10501 attaaatcaa cgatatgcag caaatgctct ttagataaag ctttgaattc aataatacca
    10561 tcgaaacgat tcataaactc tgggctgaag aagttgctta attcaccaag gacagaactt
    10621 gtccgtcctt ctctagcagc accaaatccg acagaagctt cgcttttacc tgttccggca
    10681 ttagaggtca tgataataat ggtgtccttg aagctgactg ttcgcccttg gccgtctgtt
    10741 aagcgaccgt catcaagaac ttgtaagaac atgtgcatga cgtcaggatg ggctttttcc
    10801 acctcatcta agagaataag ggaataagga ttgcgacgaa cttgttcggt tagctgtcca
    10861 gcttcttcat agccgacata acctggagga gccccgacta atttggcgac agcgtgtttt
    10921 tccatgtatt cggacatgtc aaagcgaatc atattgtttg tcgaaccaaa gagttcaatg
    10981 gctagttgtt tagacaattc agttttacca accccagtcg gtccaacgaa taagaaagaa
    11041 ccaatagggc gatttggagt tcctaatccc acacggttac gacgaatagc cttagcgatt
    11101 ttatcaacag catcgtcttg cccgatcacg tgtgctttca gatcattggc taagtttacg
    11161 agttgagact gttccttttc ttttaagtcc ccaactggaa tattagtttt ttgctctaca
    11221 atagcttcaa tggttttttc agtaatgatg ggaatatctt gctcatcgac tttttgagcc
    11281 tgcatttctt tgtattttgt aatttgatcg cggaaataag ctgcgcgttc atagtcttcg
    11341 tctcgagtag cttgcgcctt gagattctca gcttcaataa gacgtttgtc aatttcttta
    11401 ggatcaacaa agttgagggt tagattcatt ttggaaccag cttcgtccag aaggtcaata
    11461 gccttatcag gaagaaaacg gtcttgaata tagcggttag ataaatgagc ggcagcttca
    11521 atagcggctg ggctatattt gacatgatga tagtcttcgt atttcggttg gatacctttt
    11581 aaaatcgtga tggtttcctc aacagaaggt tcatcaactt taacgggttg catacgtcgt
    11641 tctaaggcag cgtctttttc aataatacgg tattcattta atgtagtagc accaacgagt
    11701 tgcaactcac cacgggccaa ggctggtttt aaaatattac cagcatccat attgccgtct
    11761 cctgcagaac cagcaccgac aatctcatga atttcatcaa taaagagaat cacatccttg
    11821 cgattgcgaa tttcttccat taatttttgc atgcgctctt caaactgacc acggatacct
    11881 gttccctgaa cgaggctaac cacatcaaga cgaatcactt gcttgccttg gagtttttga
    11941 ggaacagtac catcaataat tttttgagcc aaaccttcta caacagcagt tttaccaact
    12001 ccaggctcac caattagcac aggattattt ttagtacggc ggttgaggat ctcgataacg
    12061 cgtgtaatct cttcgtcacg accaataaca ggatcaatat taccatttct tgcaatatct
    12121 gtgacattaa tcccaaactc ttctaataag ccctttgctt gctgatttgg tgtttgtggc
    12181 tgagcaggtc gttgtccgtt gtagttacca ccatagcgtc ctccgccatt tccattttgc
    12241 cctgcctgag taggtggggt atttggaaga ttaccaaaag ctctaaaatt attcaaatca
    12301 ccaaaaaagt catcaaagaa aggacttgtg gatctatctt gtgctctata tcctggggtt
    12361 aggccattta aaatagaatt ggcaggatcg gatttcatga tttgataaca attttgacag
    12421 agatcaacct gtctttgttt tccattaaca cttgtataaa gatgaatagt agattcgttt
    12481 aaattacaat tttgacacag cataatatac ctccgagggt ttatctaaaa gtcaaagtca
    12541 tttagtcaaa aatggtcaaa ctttatattc atattatagc accacggctt gggaaatcaa
    12601 gtaaaaagtt tatcgcttta gcgttagctt ttagagagta acatgacaga gtaactttat
    12661 taagtttcca atgagcaaat gtttaaaatc attgaaaaga gtaaaaaaag taaaatatca
    12721 ataaatatat tactttcctt gttagtttcc cttgttttgt gttaaaataa gagggataaa
    12781 aaacgaatag gagaaacgaa atggaatcac atttggtgag aatcatcaat cgtttggagt
    12841 tgatggtgac agatggcggt aatctcaagc gaaattttga acgcgatggt gttgttgttg
    12901 cagaagttgc cttttcaaat gatcctgaaa atggacctgt tttcacattg cgtgatgttg
    12961 aagcgcgtga gtcatattcc tttgatagca ttgacttgat tgcaatggaa atctacgatt
    13021 tattatatta agcttgacat agtaaagaga cttgcctgag gcaggttttt ttattgtcaa
    13081 aaagtattgt attaatattc atcagatggt ataattatct ttattgtaat gaacctagga
    13141 cttatgagga gatataaatg gatttgtcat ttttgcccaa atactgggcc tactttaact
    13201 acggtgtact tgtcaccatt atgatttcag tcagcgttgt cttttttgga acccttattg
    13261 gtgtcttggt aaccctgatt aagcgtagtc atgtgaagcc gttgacctgg gtcgttaatc
    13321 tttacgtttg gatctttcgg ggaacaccta tggtggttca aatcatgatt gcctttgctt
    13381 ggatgcattt taacaatatg cctactattg gttttggggt tttagacttg gacttttcaa
    13441 gactacttcc tggaattatt atcatttcat tgaatagcgg tgcttatatt tcagaaattg
    13501 ttagagcagg tattgaggct gtaccaaaag ggcaattaga agcagcttat tcactaggta
    13561 ttcgtcctca aaatgccatg cgttatgtga ttttgcctca ggcctttaaa aatattttgc
    13621 cagccttagg aaatgaattt attaccatta ttaaggatag tgctttttta caaaccattg
    13681 gagtgatgga actttggaat ggtgcccaat cagtggtaac ggctacttat tctccaattt
    13741 cccctttact ggtggctgct ttttactact taatggtcac aacagtgatg gcacagttat
    13801 tggcagtctt agaacgtcac atggcgcaag gaggtaatca ttgatgactg aggccattat
    13861 ttcaattaaa gacttgcaca agtattatgg gcacaatgaa gtgcttaagg gaattgattt
    13921 agacattatg ccaggagagg ttgtggtgat tattggcccg tctggttctg gaaaatcgac
    13981 cttacttcga accatgaatc ttttggaagt accaactaag ggacagatta ggtttgaggg
    14041 gattgatatt accgataaga agaacgatat tttcagcatg cgtgaaaaaa tggggatggt
    14101 ttttcagcag tttaacctct ttcccaatat gactgtttta gaaaatatca ctttatcgcc
    14161 aatcaaaact aagggaatgg ctaaagcaga ggctgacaaa acagccttga gcttgttgga
    14221 caaagttgga ttatcagaaa aagccaaggc ttatcctgct agtctttctg gtgggcaaca
    14281 gcagcggatt gcgattgcgc gtggactggc tatggatcca gatgttttac tctttgatga
    14341 accaacttca gctctagacc cagaaatggt gggtgaggtc ttggctgtca tgcaagattt
    14401 ggctaaatct gggatgacta tggttattgt gactcatgaa atgggctttg ctaaagaagt
    14461 cgcagatcgt gtgattttta tggatggtgg cgttattgtg gaagaaggaa gtcctaacca
    14521 actttttgat ctgactaaag aagaacgtac aaaagatttt ttgagtagag tattataaat
    14581 ctgttctatg aattataaaa ggaagtccta aatcatttag gacttccttt tataatttgc
    14641 taaggcattt tataggagat tacttttctt tttgttaaaa taaaaagaaa tagttacatt
    14701 atttgcatag aagaaaggga tctgttatgg tttcagtgat gtggtttcgt agagatttaa
    14761 ggattgatga tcaaaaagct ttagctcatg ctattgctag tcaatcgcca accttatgtg
    14821 tgtttcaatt taacaaggag caattaaacc tgctacatag tcggaatcaa tctagtttta
    14881 ttactagcgt tttggctttt agaaagttat taaaatgtga aagtattgac ttatatctaa
    14941 tgtatggaga cttaatgacc tgttttgagc aattattgac acaattaaaa gactggacag
    15001 atgtgtattt taactatgat gaatctggat atggtcgttt acgtgatcaa aaagcagcac
    15061 aatttttcaa aaaaaatggg attgctgttc atacctacca agatcactat ttacatggta
    15121 gtcaagagat cattaaccaa tcaggtcagc cttataaagt ttttacgccc tactatagga
    15181 tttggcaaaa ttatccgaaa gagactccta ttaaagtaga actatcgcaa ggcaggtggt
    15241 taaatcttga gacaccagat gatgttttaa ggactgttga gagctttaaa gatgaaaaat
    15301 atcaggatgt tgcaactttt gatgaagcgt caaaacaact aaatcgattt attcaagacc
    15361 aattagcagc ttatcacgct aatcgagatt ttccagcgca gctagggacg agtcggttgt
    15421 ctcccttttt aagaatagga gctattggca ttcgcacggt atatcacgct gtgcgtcaag
    15481 caccaaatag tctagggcaa gctacttttt taaaagaatt agcttggaga gacttttaca
    15541 atatggtcta tgtggcttat cctgatcaga aaactcagcc tatccaaaaa gccttttctc
    15601 aaatcgaatg ggttaataat cctgactggt ttcagttgtg gaaagaaggt aaaacgggtt
    15661 accctattgt tgatgctgcc atgcttcagt tacaaaagac aggatggatg cataatcgtt
    15721 tacgaatgat agtagcttct tttttaacta aagatctttt atgtgattgg cgtttaggag
    15781 agcagtattt tcaacaacaa ctaattgatt atgatgctgc cagtaatatc ggaggatggc
    15841 agtgggctgc ttccactgga acagatgctg ttccttattt tagaatattt aatcctgtta
    15901 ctcaaggtaa gcgttttgat cccaaaggcg agtttattaa agcgtatttg cctcaactag
    15961 aacacgttcc agagaagtat ctccacgaac cgtggaagat gccaaaatac cttcaagaga
    16021 gtgtatcctg tattattggc acagactatc ctcaaccaat tgtcgatcat gctaaacaac
    16081 gtgaacaagc tattgcaaag tatgagtggg caaaagaaaa agcaaaaata gaatgactgt
    16141 tctcattata agagtttaaa caaaaagtta tcatgaatta agattattta atttaaaaaa
    16201 taagttgact ttatttagat tatttgatac tattcagttg tctcccttag agaaagcgat
    16261 ttcttgtttt ggagctgatt tttaccattt ggtcttagaa taggatgagt aatatgactt
    16321 acaacgaggt atatcaagaa tggttgcaca ataatgatct tagtgatgat attaaagcag
    16381 atttagcagc cataaaagac aatgaggctg agattcaaga tcgtttttac aaaacacttg
    16441 aatttggaac agcagggcta agaggaaaac ttggagcagg caccaatcgc atgaatacct
    16501 atatggttgg taaggcagca caagctttag ctaatactat tattgatcat ggacctgaag
    16561 cggttaaaaa gggcattgcg gttagttatg atgttcgcta tcaatctaga acatttgcag
    16621 aattaacatg ctctattatg gcagctaacg gtattaaggc gtacctttat aaagggattc
    16681 ggccaacacc aatgtgttcg tacgctattc gtgctttggg atgtatctct ggtgttatga
    16741 ttacagctag tcacaatccc caagcttaca atggttataa agcttattgg caagaaggtt
    16801 ctcaaatttt ggatgacatt gcggatcaaa ttgcacaaca catggctgca ctaactcagt
    16861 atgaggaaat caaacaaatg ccttttgaaa aggctctgga cagtggactt gttacttata
    16921 ttgatgagag tattgaagaa gcatataaaa aagaagtgct tggtttaacg attaatgata
    16981 ctgacattga taagtcagtc cgagtagtct ataccccttt aaatggtgtt gggaatctac
    17041 cagtgcgtga ggttttaaga cgccgcggtt ttgaaaatgt ttatgtggta cctgagcagg
    17101 aaatgcccga tcctgatttt acaacagttg gctatcctaa tcccgaagtc cctaaaactt
    17161 ttgcatattc agaaaaatta ggtaaggcag ttgatgctga tattttgatt gcaactgatc
    17221 cagattgtga ccgtgtggct ttagaagtta aaaatgcagt cggtgactat gtttttctca
    17281 atggcaataa aatcggagcg cttttatctt actatatctt ttcacaacga tttgacttag
    17341 gcaatttacc ggctaatcct gttttagtga aatccattgt aacaggagac ttgtcacggg
    17401 ctattgctag ccattatggt attgaaaccg ttgaaacatt gactggtttt aagaatattt
    17461 gtggcaaggc aaacgaatat gatgtgacga aacaaaaaaa ctacctgttt ggttatgaag
    17521 aaagtattgg tttttgctat ggcacttttg ttcgtgacaa agacgctgtt agcgcctcta
    17581 tgatgattgt agaaatggca gcttactaca agaaaaaagg gcagaattta ctagatgttt
    17641 tgcagactat ttatgcgaca tttgggtatt ataatgaacg tcaaattgcc ttggagcttg
    17701 aggggataga aggacaaaaa cgcattgcga ggataatgga agatttcaga cagacaccaa
    17761 tagctagtgt tgcagagatg gcgttagaca agacaattga ttttattgat ggctatcaag
    17821 attttccaaa gcaaaactgt ctcaaatttt atttggatga tggttcttgg tatgcactta
    17881 gaccatcagg aacagagcct aaaataaaat tttatttata tactattggc caaacacaag
    17941 aaaatagtgc aacaaaatta gatgctattg aagcagcgtg tcgcacaaaa ataaatcaag
    18001 ttaattaaac atcaaaaatg gataacactt ttacactatt tttccatata aacaactaca
    18061 aaaggaggtg agacttttag gcaccttctt tttcttgtag gtgccactaa tcaatttaat
    18121 cgactcaaac caatactaaa aaataagtaa gagtataaag aacaggcatc tatttttttg
    18181 ttataataga aaaatgaaat taaagggaga tgtcaatgac agaactaatt gatggtaaag
    18241 ccttagctca aaagatgcaa caagagttag cagctaaagt caacaatcta aaacaaaaaa
    18301 aaggaattgt accaggctta gccgttattc ttgtaggtga tgatcctgct agtcaggtgt
    18361 atgtccgtaa taaagagcgt gcagctctta ctgtaggttt taaaagtgag accgttagat
    18421 tatcagaatt catttgtcaa gaagagctta ttgcagtaat cgaacgttac aatgcagata
    18481 acactattca tggtatttta gtgcagctac ccctgccaaa tcatattaat gataaaaaaa
    18541 ttattctcgc cattgatccc aaaaaagatg tggacggttt tcacccgatg aatacaggtc
    18601 acctttggtc aggacgtccc ttaatggttc cttgtactcc atcagggatt atggaattgc
    18661 ttcgagaata taatgttaac cttgaaggta aacatgccgt cattattggc agatcgaata
    18721 tcgttggaaa accaatggca cagctcttac tagacaaaaa tgcaacagtc acgttgacac
    18781 attcaagaac acgtcaatta gaagaagtat gtcgctgtgc agatgtgttg attgtggcaa
    18841 tcggacaagg tcatttcata acaaaacaat atataaaaga tggtgcgata gtgattgatg
    18901 tgggaatgaa ccgtgatgat aatggcaagc taattggaga tgtggccttt gatgaggtgg
    18961 cagaagttgc agcgaaaatc acccctgtac caggaggtgt cggtcctatg acgattgcta
    19021 tgttgctaga gcaaacttat caatctgccc tccgtagtac tcataaatag ttataattag
    19081 acaattcaac ataagagaat ataagaagtc agcaatggct tccttttttg tttttctgct
    19141 cactatttat ccagaaaaat ggtataattg cattagtatg caaagggact atgtcaggtc
    19201 caactaagtg aaaggtggct tgatggcaga ttatttaacc gtcactcatt tgacgaaata
    19261 tttaaaatta aaatttgacc gtgaccctta tttggaacgg gtttatctga ctggtcaagt
    19321 gtccaatttt cgaaaacgac caactcatca atatttttcc ttaaaagatg aaagtgctgt
    19381 gattcaagcc accatgtggg caggagtcta taaaaaacta ggattcgacc tagaagaagg
    19441 catgaaaatt aatgtaattg ggcgagtcca actttatgaa cctagtggct cttactctat
    19501 cgtgattgaa aaggcagagc cagatggtat aggtgccttg gctttgcagt ttgaacaatt
    19561 aaagaaaaaa ttaacggcag aaggttattt tgagcaaaaa cacaagcagc ccttgccaca
    19621 gtttgtatca aaaattgggg tcattacaag tcctagtggt gctgtgattc gagatattat
    19681 cacaaccgtt tcacggcgtt ttccaggggt tgagatttta ttattcccaa ctaaagtaca
    19741 aggtgatgga gccgcccaag aagtagtggc taatattcga agagccaatc aaagagagga
    19801 tttggacttg ctcattgtcg gccgtggagg tggctcgata gaagaccttt gggccttcaa
    19861 cgaggaaata gtggttcagg ctatctttga atcgcaactt ccagtgattt cgagtgtggg
    19921 tcatgaaaca gacacgactt tagcggattt tgtggcagat cgcagagcag ccacaccaac
    19981 agcagcagca gagttagcaa cgcctattac aaaaacagat cttatgtctt ggatagtaga
    20041 gcggcaaaat cgttcctatc aggcctgctt gaggcggatt aagcaacggc aagagtgggt
    20101 ggataaactc tcgcaatctg ttatttttag gcaaccagaa cgattatatg atgcctacct
    20161 gcaaaaaatt gatcgcctta gcatgaccct gatgaatacg atgaaagatc gtctgagttc
    20221 cgccaaagaa aacaaggttc agttggacca ttccttggcc aatagtcaat tacagacaaa
    20281 aatcgagcga taccaagacc gtgttgctac cgctaagcgt ttactgatgg ctaatatggc
    20341 tagtcaatat gatagtcagc tggctcgctt tgaaaaagca caggatgctt tgctatcact
    20401 ggatgccagc cgaattatcg cccgtggtta tgcaatgatt gaaaaaaatc aagcactggt
    20461 agcctctgta agtcagataa caaagggtga tcagttaacc attaagatgc gtgatggaca
    20521 attagatgta gaggtaaaag atgtcaaaaa cgaaaacatt tgaagaaaat ttacaagatt
    20581 tagagactat tgtgaacaaa cttgaaaatg gggatgtccc tttggaagaa gctatttcag
    20641 aatttcaaaa aggaatgctt ctctcaaaag aacttcaaaa gaccttacaa gcggcagaaa
    20701 aaacactcgt caaagtgatg caagctgatg gcacagaagt agatatggat gattaatgga
    20761 caaattagct agaattgacg aagccattcg tcgctactat aagacgacta gtaacggtgt
    20821 atctgaagag ttgattgatg ctatcttgta ttctgttgac agtggtggca agcgcattcg
    20881 cccacttatc ttattagaga tgattgaggg atttggggta tcgttacaga atgctcattt
    20941 tgatttggct gcagcccttg aaatgattca tacaggaagt ctgattcacg atgatttgcc
    21001 agccatggat aatgatgatt accgacgtgg tagactgacc aatcacaaac aatttggaga
    21061 ggctactgct attttggcgg gagatagctt atttttagac ccctttgggt taatagctca
    21121 agctgaatta aatagcgagg ttaaagtagc cttaatccaa gaactttccc tagcttcagg
    21181 aacttttggc atggttggtg gtcagatgct agatatgaaa ggggaaaatc aagctttgag
    21241 tctccctcag ttgtcactga ttcacctcaa taaaaccgga aaattattaa cttttccttt
    21301 taaagcagca gctcttgtaa cagaacaggc tattactgtt cgtcaacaac tagagcaggc
    21361 gggaatgctc atcgggcacg cctttcagat tagggatgat attttagacg tgacagctag
    21421 ctttgaagat cttggaaaaa cgcctaaaaa ggatttattt gcagaaaaag ctacttaccc
    21481 aagtttattg gggttagaag cctcctacca actgttgaca gagagtttag atcaggcttt
    21541 gacgattttt cagacactcg aaagcgatgt aggctttaag cctcaaataa ttacaaaact
    21601 gatagaaggg ttacgactta atgcctaaag aaagagtaga tgtgttagcc tataagcaag
    21661 gattatttga gaccagagag caagctaagc gtggtgttat ggcaggctta gtggtctctg
    21721 tgattaatgg ccaacgctat gacaagccag gtgacaaaat tgacgatggg actgagttaa
    21781 aacttaaagg tgaaaaactc aaatacgtca gtcgtggtgg attaaaactg gaaaaggggc
    21841 tgcacgtttt tggtgtatca gttgctaatc aaattgggat tgatattggc gcttcaacag
    21901 gtggctttac cgatgttatg ttacaagatg gggccaaact agtctatgcc gtcgacgttg
    21961 ggactaacca gttggtatgg aaactcagac aagatccacg agtaagaagt atggaacagt
    22021 ataactttcg ttatgctcag ccagaggact ttaatgaggg acagcctgta ttggccagta
    22081 ttgatgtgtc ctttatttct ctcagcttga ttttgccagc cctgcataac gttttgtcag
    22141 atcagggaca ggttattgct ctcattaaac cgcaatttga agctgggcgc gagcagattg
    22201 gtaaaaaagg catcgtcaag gacaaacaga ttcatgaaaa agtgattcaa aaggtcatgg
    22261 attttgcctc aggttacgga tttacagtta agggacttga tttttcccct attcagggtg
    22321 gtcatggcaa tatcgaattt ttagctcatc ttgctaagtc acagacacct gaaacgttag
    22381 ccccgcattt gattcaggaa gttgttgcca aggcacataa ggagtttgag aaacatgaaa
    22441 aagagtgaac gacttgaatt aatcaaaaaa atggttttga cgcatccaat tgagacgcaa
    22501 catgacctct taagattatt ggcagagcat gggttagaat taacccaggc tactatttca
    22561 agagacatga atgaaattgg tatagtaaag attccttctg gcagtggacg ttacatctat
    22621 ggtctttctc aagatagtgg aaaaaagatc gttcaaggac ctagatcgat aaagagcact
    22681 attttagctg tatctgacaa aacaaaaggt ttagaacaac acctctattt aaaagtcgta
    22741 cctggcaata gtaaattaat caaacgttat ttattagcag atttttcaaa agctattttt
    22801 agtcttattg ctgatgatga tagtttattg ttaattgcaa agtctccttc agaagcagat
    22861 atgatacgcc aagaaatttt gctttggatg cagggtataa cctagaaaaa aataggggag
    22921 aaagtgatgt tattagaaat ttctattaaa aattttgcta ttattgatga aatttcccta
    22981 aattttgaaa atggtatgac ggttttgacg ggtgaaactg gagcaggaaa gtctattatc
    23041 attgatgcta tgaatatgat gcttggtgcg cgtgctagta cagaagtgat tcgtcgtgga
    23101 gctaataaag cagaaattga ggggttcttt tcggtagatg ctaccccaga actggttgcg
    23161 tgtctggaat catcaggcat tgctatggaa gaagaactga ttattcgccg agatatcttt
    23221 gccaatggca gaagcgtgag ccgcattaat ggtcagatgg ttaacctagc caccttaaaa
    23281 caggtcggac agtttttggt agatattcat gggcaacatg accaagaaga attaatgcga
    23341 ccacagctcc accagcaaat tttggacgct tttggtgata aggcttttga gcaattgaaa
    23401 gagaactatc agcttatttt tgatcgttat aaaagcttgc gtcgccaggt tattgacaaa
    23461 caaaaaaatg aaaaggaaca caaagatcgt attgatatgt tggcctttca gatagcagaa
    23521 attgaagctg ctgccttgag tcgaggtgag gacgaccggt taaatcaaga acgtgatcgc
    23581 ttaatgaacc acaaacaaat tgctgatacc ctgaccaatg cctacgtcat gctagataat
    23641 gacgattttt caagtctatc caatattcgc tctagcatga atgacttact atcaattgag
    23701 cagtttgatt cagagtacaa agggatgtcg acttcgattt ctgaagccta ttatattctt
    23761 gaagaagtga gcaagcaatt atcagatacc attgaccaac tggattttga tggtgggcga
    23821 ttacaggaaa ttgaatttcg cttggataca ctcaatagct taacccgtaa atacggtggt
    23881 aatgtgaatg atgtgcttga ctactacgat aatattatca aagaatacca gctattaaca
    23941 ggagacgact tgtcttcagg ggatctagaa tcagaattga aagccttaga aaaacaattg
    24001 gttgctgcag ccgctaactt gagtgaacgc cgccatcaat tggcagagca attagaagct
    24061 gagattaaag ctgaacttaa ggaactttat atggaaaaag cagatttcaa agttcacttt
    24121 accacatcaa aattcaatcg tgatggtaat gaaagcttgg aattttacat ctctactaat
    24181 ccaggcgaag gatttaagcc ccttgtcaag gtggcttctg gaggagagtt atcacgcctt
    24241 atgttagcca tcaaggctgc tatttctaga aaagaagata agacgagtat tgtttttgat
    24301 gaagtagata caggtgtttc tggtcgcgtt gcgcaagcca ttgcccaaaa aatttataaa
    24361 attgggcgac atgggcaagt tctcgctatt tcacacttac ctcaagttat tgctattgct
    24421 gattatcagt attttatttc taaagaaagt aaagaagagt ccaccgtttc taaggtaagg
    24481 ttattaactc ctgaagaacg tgtggaagaa attgctagca tgattgcagg aacagatatg
    24541 acacaagctg ctcttacgca ggctcgtgaa ctacttgcca aacattaaga ttgtgtttgg
    24601 tatttgatat tttcataatt agatgacatt gattttttag gtgctaaaat aatcattgtg
    24661 ctagaccatt tttcctctgt taatctggct tggtttgcct tgacaaacct ctgagaaata
    24721 gtagaataga taagagaatt ttaagctgag gggatagaaa tgactagtaa aaaagcgtgt
    24781 ttatcaagca tcattgtgtt agcaagttta acgtgtggaa atgatactgt tagtgccaat
    24841 catctctcag caactggaga taagtttgat gattgctcaa cacttgttga aaaagatgtg
    24901 gcccctaaag atgaacttga gatgttagca tggtcctcgt ctcaaacaac tgatgatgct
    24961 gacagagact atgaagattt tctcgatgat gattctttta tttctcaaaa tgaaactgat
    25021 aagatgtttg agaatttaac tgatgatagg ttattagatg aattagatga attagatgaa
    25081 ttagatgaat tagatgaatt agatacaatt gagccagagc aaaatgtaat aatgcctagt
    25141 gacgatgagc tatttgattt aactgatgct gttgagacac gccttactgt ttctagtgct
    25201 ccccatttag aggctgaatt gccgaaacca catttgagga gcctatcaga tacagcactg
    25261 cggtctggtg aaattagagg acatttagat aacaaactgg acgctttgtc tgtaacagct
    25321 acaaagttag cattaacgat ggctcaaaaa tttgatttga caacgcatgt ctattctata
    25381 ggtgaaagct ttagtgaagt attagctgct cattatgaag acagaaaagc agaatcagct
    25441 ttttctaaga aaaagagatt tcaccttcct attgctactc cagatgttgt tatagaggag
    25501 ttaaggcgcc tagtctcttc tattggaagt tcaaaagaag atgtttcagt tccttataat
    25561 cggaagctag gtatggcagt tgcaaaaaga aaaatagccc tgccacaaac gggagaggag
    25621 ttctcttatt atccagcttt acttggttta atgatattag gattaacgcc gattatgata
    25681 ccaaagaaga taaataatta ggtaataagt tattgtagtt gtaaaagacg gggcaaatgt
    25741 tcaagcgtga aaaggttgac ttttgcctcg ttttgtatct cgttattgct aaggcatttt
    25801 cttcgagcag ctagtgctcg ccatacctat ctaccgagtg attattcaat agcactacca
    25861 gttttgcttt atttagtgag gagtgttaga ataaagaggt gagaaactag tttagaatgg
    25921 aaaaatacat gggaactata aaaattgtta cagattcatc aataactatt gaaccagaat
    25981 taattaaagc tttagatatt actgtagtgc ctttatctgt catgattgat agcaaattat
    26041 attctgataa tgatttaaaa gaagaaggtc attttttgag tcttatgaag gctagcaaat
    26101 cccttcccaa aaccagtcag ccaccggttg gtctctttgc tgaaacttac gaaaatttgg
    26161 tcaaaaaagg agtaactgac attgttgcta ttcacctctc accagcttta tcaggtacta
    26221 ttgaagcttc ccgtcagggg gctgaaatcg ctgaggcccc tgttacagtt ttagattcag
    26281 gatttactga tcaagccatg aaatttcagg tcgttgaggc agcaaagatg gcaaaagcgg
    26341 gtgctagttt gaatgagatt ttggctgctg ttcaagctat caaatcaaaa acagagctct
    26401 acattggtgt atctacctta gaaaatttag taaaaggagg tcgtattggt cgtgtgacgg
    26461 gtgttttgag ctcgctactt aatgtcaaag ttgttatggc acttaaaaat gatgagttaa
    26521 aaacgcttgt caaaggtcga ggtaataaaa catttacgaa atggttagat agttacctcg
    26581 ctaaaaatag tcatcgcccg attgcagaga tagctatttc ttatgctggt gaagctagcc
    26641 tggcattaac cttaaaagaa agaatcgcag cttattacaa ccactctatt tcggttttag
    26701 aaacaggctc tatcatccaa acacatacag gagaaggagc ttttgcggtt atggttcgtt
    26761 atgaataatc gtcatttatt tagtgggata tttttctttg ttattagttt atgtctggcc
    26821 tttttattgc taaatattat tatccctaag tcaaattcac gtttgaaaaa gagtgatttt
    26881 ctgacaaaag aacaagtagc tatccaatat gttgctatag gagattcatt gacagaagga
    26941 gtaggtgatc taactcatca aggtggtttt gttcctttgt taacgaatga tctcagtgaa
    27001 tattttaagg ctaatgttaa tcatcaaaat tacggcgtat ctggtgatac cagtcaacaa
    27061 attcttgata ggatgataaa acaaaagcag atacagttat ctttaaaaaa agcagatata
    27121 atgacgttaa ccgttggtgg taatgatgtt atggcagtta ttcggaagaa tttagcggat
    27181 ttgcaagttt ctagttttag aaagccagct cgtcagtatc aaaaacgatt aagacagatt
    27241 atcgagttag ccagaaaaga taataaagat cttcctattt ttattttagg catctataat
    27301 ccgttttatt tgaattttcc agaactaact gatatgcaaa aagtgattga tgactggaat
    27361 accaaaacta aggaggttgt tggagaatac gatcgtgtgt actttgtgcc aataaatgac
    27421 ctcttgtata aagggataaa tggacaagaa ggaattgttc attcttcagg agatcaaact
    27481 acaattgtca atgatgcctt gtttactggg gaccattttc acccaaataa tactggctat
    27541 caaatcatgt caaatgcagt aatggagaaa ataaaaaagc atgaaaaaaa aatcaaacct
    27601 taattggtgg aagtggagct tcttatgtct gcttgctttt aataccgcct ttttgatggt
    27661 tattgcaagt cgtctcattc aagtaagaga acctgagtca gaactgattg ctaaaaaacc
    27721 agttaaaaat atcaaaattg gtacatttgt cacaaccaga gaacagctta acgaaactgt
    27781 agcaagttat cttaaagatt atcagactaa aaaaatgtct tataaatttt atgcgacatc
    27841 ttcttctatt ttgtttgaag gaacttatca attattaggg tatgaagtcc ctttatatat
    27901 ctattttcaa cctcatcgtc tagaaaatgg agctgtccaa ctacaggtga tctctttttc
    27961 agtgggaact ctgccactcc cagaaaaaga tgttttgcag tatttgaaat caagctacaa
    28021 attgccaagc tttgttaaag tgatgccaaa tcaatcagct atcgttgtta atttacaaga
    28081 tatccaaaat gatgctaagg tttatttaaa ggccaagaaa attgatttat ttaatgatga
    28141 aatcagtttt aacatctata agaaataagc tcaaataacg ttaaatactt gacctaatcg
    28201 ctttttttag atatgataat atctgttaaa gcattaagct tactaattat ttggaggatt
    28261 tgttaaatgg ctaacaaaca agatttaatc gcaaaggttg cagaagcaac tgaattgact
    28321 aaaaaagatt cagcagcagc agttgatgcc gtgttttcta caatcgaagc tttccttgct
    28381 gaaggtgaaa aagtacaatt gatcggtttt ggtaacttcg aagtacgcga acgtgcagct
    28441 cgtaaaggtc gtaacccaca aactggtgca gaaattgaaa ttgcagcttc aaaagttcca
    28501 gccttcaaag ctggtaaagc tcttaaagac gctgttaaat aattcgtcta gaaaaatctt
    28561 gttgctatcg atgtttattg atagcgacaa ggttcttttt tatatttggg gcatatttgg
    28621 ggcataaagt tagtagtttt ctcttcagtt aagccaagtt ctaatgcatg cactctataa
    28681 tggtcagtca tccttctatt agtatatcat ttccgcaggt agggggagtt tttttcatat
    28741 ttgcaaatag tcgaagttag gatttttgaa agcaaaaggt aagtttaaaa aagtttattt
    28801 agaatgcttc taaattactt gacttattta tttagaatta ttataattaa tgtatcttaa
    28861 agattgaata acttttaatt gcgagggaac taaaaatgac aatcagacaa tggatggcag
    28921 accatcttca tttaatggag actttagcgt gtttggtatt aataataatt ggcctagcct
    28981 ttttacactc atttccacaa gtggcttccg ctattttcat tacagccttc ttgattggag
    29041 gatatgcgtc tgcaaaaacg ggtatattgg atttggtgaa gaacaaacac ttgtcagtgg
    29101 atattttgat gattttagca gctatcggtg ctggaattat cggctattgg ctggagggtg
    29161 ctctgcttat ttttatcttt tcgttgtcca atacgcttga agaaatggcc atggaaaaaa
    29221 gtaaggatgc tatttcagcc ttgatgtcct tgacgccaga tacagctcgt caataccaag
    29281 aagatggcca tattttagaa gttgagacca gatccttgag tgttggtgac cgtttacaag
    29341 ttcgtaaagg cgaagctgtt ccaattgacg ggcagttgct tagtcctttt ggtcaatttg
    29401 atgaatctat ggtcactggt gagcctatca ctgttgataa ggcagaaggc caggatctga
    29461 ttgggggaac cattaaccaa ggacaaacca tagatatgtt ggttactatt gaaaatgacg
    29521 atactctctt tgccaagatt attaatctgg tggaatctgc ccaagaaaag aaaagcaaaa
    29581 ctgccacctt tatcgaaagc ttagaagatg gttatgtcaa atttgtgctc gtccttattc
    29641 ctgcctttat cctctttagc cactttgtgc tttcttggac ttggttggct gctttttacc
    29701 gagggatgat tctcttaaca gtagcttcac catgtgccct aattgccagt tccacacctg
    29761 ctagcttggc tgctatttct cgtgcagcca gaaagggatt gattatcaaa ggaggggata
    29821 ttgtcgataa catgggagat attaaggctg ttgtcatgga taaaacggga acgctcaccc
    29881 aaggaaaacc ttctgttgtg aatgctcatt atttggaaga tgagttgctc gtgaatagac
    29941 tggtaaaagg agcagagact gctagtaccc atcctatttc taaagccctt cttgaataca
    30001 ctgaaaaatt ggagccactg acctttgacc acttagaaga aatttctggg aaaggttttc
    30061 agggcttcta tcaagggcaa gaatggcgaa ttggcaagaa aaccttcatt ttggaaaagg
    30121 ttcaagacct atcagctttt gaagaaacta ttcaagtgga agaaaatcaa gggaaaaccc
    30181 taatctttgt ttcacgtgac catcaattga tagcttacta tgccctcttg gatgatatca
    30241 aaatagaatc aaaacgtgct attaagtctc ttcatgccat gggaatcaaa acagtcatgt
    30301 taacaggtga ccaagaacga accgccaatt atgtggcaca aaaacttggt attgatgaag
    30361 tggtagccaa ctgtatgcct caagataagg tggctaagtt agcagaatta aagaccaaat
    30421 atggttttgt ggccatggta ggagatggta ttaatgatgc tcctgccctt gctcaagcag
    30481 atgtttctta tgctattgga tcaggaacag atattgcaat ggaaagtgca gacagtgtga
    30541 ttatggatga cttgactcgt attccatttt cgattcaact ttcccgcaaa atgaagacca
    30601 ttatcaaaca aaatattgtt tttgccttat ctgtgattac cttattgatt ttagccaatg
    30661 tttttcaggt agttaacttg ccgcttggtg ttgttggaca cgaaggctca acgattttag
    30721 tgattttaaa tggcttgcgt ttactttctt ttaaataatt tagaaacttg cttgaaaact
    30781 tgaaagtgtt tataataata gtaagactta tgaaagagaa aaccgccgta tgtttactat
    30841 tatgatcatt ggtttagctg tattttcaat aattaaaatc attctatttt tctattttta
    30901 tcagcaattt gagcgcaagc aaaaaagaaa agttgaatca aacaaccagc aaagacagtc
    30961 ccaagaaagt gacgctgtcc cttcaaaaaa attcccattt taaaaagctt ggaaagtgta
    31021 caaagtgcac atttccaagc ttttttgact attaaggtta atctttgtaa cgtaagttcc
    31081 cacgaaaatc gtctaagctt tggtagcctt tttctaccat aatcgttttt agttccttag
    31141 tgacccgttc aaagatagct ggcccttctt gatgaagggc tgtcccaatt tggaccatgc
    31201 tggcgccaca aagaatatgt tcaaaggcat cgcgtcctgt tttaactccc cctgtaccaa
    31261 taatgtggat agaaggtttt aagcgtttgt aaaacgcatg gacattggct agagcagtag
    31321 gtttgatgta atctccacct ataccaccaa agccattttt aggcttgatg aggacttgtt
    31381 catcctcaat gaccagccca tttccgatag aattgacaca gttaacaaag gaaagggggt
    31441 atttattgaa aatcgcagcc gcttgatcaa aatgcacaat gtcaaaataa ggaggtaatt
    31501 tgataccaag aggtttagtg taataggtaa agatgttctc tagaagttga tcagtggttt
    31561 caaaatcata agcaatctgt ggttttcctg gaacgttagg gcaagaaagg tttagttcca
    31621 ctagaccctc ataatctgaa gccatgatgg cttttaaaat ggtttcggtt tcagtaggag
    31681 atagcccgac aacggagaga aagtgaggtt tatgttgccc ggttttggca agatcactga
    31741 caaagtctaa gtagtagcga aaaccattat tagggagtcc cattgaattg atagaaccaa
    31801 gacgagtatc tgcgtagcga ggttctggat tacctggacg aacttcaagc gtccctgttt
    31861 tggtgacaaa ggaagcggct tgagactttt caacctccat aagctcttct tttgtcatgc
    31921 agtaaacacc agcagcattc atcaaacagt tatcaaaaga gaaatgacca atttgcgtag
    31981 cagtagaaac cattatttcc tccatatttt agacaaattt tttctattct accactaggc
    32041 atgaataata gcaagctatt ttcacaaaaa tgtaaatata ttactgttat tgacgaacat
    32101 ttgaaatttt catgatagtc acattatgat tttcaataaa gtcagaatag actagctttt
    32161 ttgctatatt ttttgtaaaa taggaattgt aaaaaggtag caacctttaa attaaaagga
    32221 gatattaact catggtaaaa ttggttttcg ctcgccacgg tgagtcagaa tggaacaaag
    32281 ctaacctctt cactggttgg gcagatgttg atctttcaga aaaagggaca caacaagcga
    32341 ttgatgcagg taaattgatc aaagaagcag gtattgaatt tgaccttgct ttcacttcag
    32401 tattgacacg tgctatcaaa acaactaacc ttgcccttga aaatgcaggt caattgtggg
    32461 ttccaactga aaaatcatgg cgcttgaacg agcgtcacta tggtgctttg actggcaaaa
    32521 acaaagctga agctgcagaa caatttggtg atgaacaagt tcatatctgg cgtcgttcat
    32581 acgacgtatt gccgccagct atggctaaag atgatgagta ttcagcacac aaagaccgtc
    32641 gttatgctga tcttgaccca gctcttattc cagatgctga aaacttaaaa gtaactcttg
    32701 aacgcgcaat gccttactgg gaagaaaaaa ttgctccagc tcttcttgat ggtaaaaacg
    32761 tctttgttgg cgcacatggt aactcaatcc gcgctcttgt gaaacacatt aaaggtcttt
    32821 cagatgacga aatcatggat gtggaaattc caaacttccc accacttgtt tttgaattag
    32881 atgaaaaact taacattgtt aaagaatact accttggtgg tgaataactt aaaaaccaga
    32941 ctttggtctg gttttttggt tctatatcct aagaagaaag aaaaccctgc ttaaaaatat
    33001 gatatgatag aaataaaaaa ggatagatag attatgaaag cagaagatcg tcgtcaaaaa
    33061 attattgagt gcttaaatag tgaacaaaaa gctgtatctg ctactcgttt aggtaagtta
    33121 ttaggagtga gtcgccaagt aatcgttgga gatatagctc ttcttcgagc tcagcagatt
    33181 gatattattt cgactccaaa aggttatatt atgtcaacag cgctttatag tcaccaattt
    33241 tgtgcacgta ttgtgtgcca acataatgta gaagaaacta aaaaagaatt agaaattatt
    33301 ttagctcatc aagggattat tacgacggta gaggtagaac atcctattta cggtatgata
    33361 acagcccctt taaatattaa gacacactct gatgtaacta atttcatgtc caaactcagt
    33421 caatctaaag cagagttatt gtcttcgttg acagaaggac tacatagtca cttaatttcg
    33481 tgtcctagtc aagaagcctt tttagctatc aagcatgatt tagaattagc aggtatctta
    33541 tacaaaggaa tataactata gtatattatg ccattgatgg ttgttatgaa taccatgcta
    33601 aaatattcta ttgattattt atcagcaaca aggtatcgtt taaaaatacc aaaagataca
    33661 ggtgtcttga tagttattgg tttttaaggt atactatttt tgaaaaggag ataaaatgac
    33721 taaaaaacca acacaactaa tagcttatac ctctattttg gtcgcatttg cgattttgat
    33781 tccgataatc atgcctctta agcttattat tggaccagct tcctttactc tggcgagcca
    33841 tgttcctttg tttttggcta tttttatgtc gattccagta gcaattttgg tcgctcttgg
    33901 taccacatta ggttttttat tagctggact tcctttaatt attgttttaa gagcactctc
    33961 tcatttattg tttgctattt tggcagcgtg gtggttaagt agaaaaccac aactgatgac
    34021 atcggcagta aaatgtttta gttttgcgtt tttcattaat gtcattcatg gcttggctga
    34081 atttttagtt gtctatattt taacagcaac cacagcaact tctatgtctt atttttggtc
    34141 tatgctaggc ttgattggct taggttcgct tattcatggc atattggatt tctatcttgc
    34201 tttagttcta tggcgttttt tagcaaaaaa cttaaaactt cccaccataa atgcctaaga
    34261 ctaaaataga gatagttata tgataatgac gagccctttc ttgttgaaag ggcttgcatt
    34321 ttttaggaaa attgatatac taaagtgtgt gtttgtgaat acagtaacaa aaggagatat
    34381 catgaaaaca ccagaacaga ttttagaagc aactattcat attggggaac ataaggttac
    34441 caaaactttt ttggctaaat ctatcttagg ctttattggt ggagcgatga ttagccttgg
    34501 ttatttactc tacgtgagaa ttgccgccag tggtttagaa acttttggtg ctttttccag
    34561 tatcgtagga gcttgtgctt ttccgattgg tctaattatt attttaatgg cgggtggaga
    34621 attaattaca gggaacatga tggctgtttc tgcagctttg ttggccaaaa aaattaagtt
    34681 tagcgagctt gccaagaatt ggcttatcat taccttgttt aatgtgattg gagctgtttt
    34741 tgtagctttt gtgtttggtc attttctagg cttaacatca gctggtattt ttaaagaaga
    34801 agtgattgag gtggcccatg ctaaaatagc agcgagccct ttgcaggcac tagtatcagg
    34861 aattggttgt aactggtttg ttggtttggc cttgtggcta tgctatgggg caaatgatgc
    34921 tgctggtaaa ttccttggta cttggtttcc tgtcatgacc tttgtagccc ttggttttca
    34981 gcatagtgta gcaaatgctt ttgtcattcc tgctgctatt tttgaaggag gagcaacatg
    35041 gttggatttt gccactaatt ttatttttgt ctatagtggt aatattatcg gtggagccat
    35101 ttttgttagt tttttatatt ttaaagttta ctatcatccg caaaagagta aaactcaatg
    35161 agaaaatatt tttttagact gagggcgtcc tattctcagt cttcttttta taatttatgg
    35221 taaaataaga agcgaagttt aaaaaattta gctaaataat ggttagttta ttccctaaaa
    35281 aaggagtatt cccaaaaaat ccgtaaaaag aatttgctat gggagtagtt cccaaaataa
    35341 tgcagatcat tagttgtctt tcaaaaatag ccttgatagg gtaaaaagtg gacagtgatg
    35401 cagcaacaga ttcatcaggc gtacaaactg tcttatggtt tgtgcttaga gatttcttaa
    35461 taatgctttt ggtaatacac ttttagtgaa gaaagtgtag catgaaagct taaagataac
    35521 catgagttcg ctttatgcac tcttgttgag aaaaatagca tagtcaattg agtaaacatc
    35581 atttctgcat ggaatgaaac aattcctata aacttatatc ataaggatgg tttgcggttt
    35641 ctaaaaaagt aaaatgaatc aaaaaacaaa agccaaatat ctcaaggcca aggtaacaag
    35701 tcgagtaaaa aagtttttac ttggctaatc caaacggttc tgtcacgatt cacgctaaaa
    35761 ttggaactgc tgagacttgt atcacagaca attcagatca gaccttagta acttacaact
    35821 taaatgtagt agcttataat acaaataacg aagataatat tgcggttgct gttatgtatc
    35881 cacatattac gaatatatcg gcaaagatgt gagggcgctt tatgtggcga tatatggaaa
    35941 acaataaagg agaacttagt gctttatcca acacccattg caaagttaat tgacagttac
    36001 tctaaacttc caggaattgg tatcaagacg gcgacgagat tagcctttta tactattgga
    36061 atgtcaaatg aagatgtcaa tgattttgct aaaaacttat tagcagctaa aagagaactg
    36121 acctattgtt cgatttgtgg aaaccttacc gatgacgatc cttgtcacat ttgcacagac
    36181 acgagccgtg atcagacgac cattctggta gtagaagatg ctaaagatgt ttctgccatg
    36241 gaaaaaatcc aagagtatca tggctattat catgtgcttc acggcttgat ttcgcctatg
    36301 aatggtgtgg ggccagatga catcaacctt aaaagtttaa ttacccgtct aatggatggt
    36361 aaggtgagcg aagttatcgt agctaccaat gccacagcag atggggaagc aacgtccatg
    36421 tatatttcac gtgtcttgaa accagccggg attaaggtaa ctcgtttggc aagaggtctc
    36481 gcagtaggtt cagatattga gtatgctgat gaagtaacat tattgagagc tattgagaat
    36541 cgtactgaac tttaatgatc atgttggtgc ctttactcgc aaagagaggt tttgaaaagg
    36601 ctacatcttt ttgttataat aaaaaaacat tcaattcaga taagaaaggt tagctatgtc
    36661 caaacaaacg ttagttctat tatacggagg ccgctcagca gaacgtgaag tctcagtgct
    36721 ttcagcagag agtgtgatgc gagcagtcaa ctatgataag ttcttagtaa aaacttattt
    36781 tattactcag atgggccaat ttatcaaaac tcagcaattt tcagaaaagc catcggaatc
    36841 agaacgcttg atgacaaatg agacgataga gctaactcaa aaaataaaac caagtgatat
    36901 ctatgaagaa ggtgcagttg tatttcctgt attacatgga cctatgggag aagatggctc
    36961 tatccaaggt ttcttagaag tgcttagaat gccatatata gggactaatg tcatgtcttc
    37021 tagcatagct atggataaaa ttactactaa acgtgtctta gaatcaattg gaattccaca
    37081 agttgcctat actgtttata ttgacggaca agatttggag gcttgtttag ttgaaacttt
    37141 agcaagactt acttttccta tcttcgtaaa accagctaat atgggttctt ctgtggggat
    37201 ttccaaagcc caaacaaaag tagaattaag aaaagcgatt cagttagccc tgacctatga
    37261 cagtcgtgtc ttgattgaac aaggcgtggt tgccagagaa attgaagttg gtctccttgg
    37321 aaatgataag gttaaatcaa ctctaccagg agaagtaatc aaggacgttg atttttacga
    37381 ctaccaagca aaatatgttg acaataagat tacgatggcc attccagcag atgtagacca
    37441 gagtattgtg acagaaatgc gttcttatgc tgaagtagcc tttaaagcct taggtggttg
    37501 tgggttgtcc cgttgtgact ttttcttgac ccaagacgga caggtttacc ttaacgaatt
    37561 aaacaccatg ccaggcttta cccaatggtc tatgtatcca ctcttatggg aaaatatggg
    37621 attggcttat ccagatttga ttgaagagct ggtgacactg gcacaagaaa tgtttgacca
    37681 gcgtgagagc cacctgattt aaacctatga gatgaataaa cattgacttg gatggaacgg
    37741 caaacatcgt caagatgtga cgttcgtcct ttttttgttg ctcttttagg aagaatagta
    37801 gagccattaa gggagtttga cattttagaa atttttctaa tgttttgtgc tataatagat
    37861 aggacatcgt aaatactagt gttcttagaa agaaaacaaa atgaaattaa ccttacacga
    37921 agtggctaaa atagttgacg cccaaaataa tgtgtctgac ttagacgacg ttcctctgca
    37981 tcacattgaa tttgatagcc gaaagattac aaaaggagac ctctttttac ccttaaaagg
    38041 tcaaagggat ggtcatgagt ttattgattt agcctttcaa aatggagctg tcgctgcttt
    38101 ttcagaaaaa gaattgccgg ggaaacctca ccttcttgtt gaagactgcc taaaagcttt
    38161 tcaaaagcta gcccattatt atattgataa gatgcgcgtg gatgttattg ctgtgacagg
    38221 ctcaaatggt aaaacttcca ccaaagatat gataggagct gtcctatcaa ccacttacaa
    38281 aacttacaaa acgcaaggaa attacaataa tgagattggt ttgccttaca ccgttctcca
    38341 catgcctgac gatacggaaa aaattgttct tgaaatggga caagatcaca tgggagatat
    38401 tcgtcttctg tctgaaattg caaggcctcg tattgcagtt ttaaccttag tcggcgaagc
    38461 tcatttagaa tattttggaa gccgagacaa aatagcccaa ggcaaaatgc agattgttga
    38521 cggcatgaat tcagatggga ttttaattgc tccgggagat ccgattattg acccatatct
    38581 tccagaaaat cagatggtta tccgttttgg aaatcagcag gaaattgacg ttactggtat
    38641 tcaagaagac aaagatagct taacgtttac aacaaatgtg ttagcaacac ctgtgtccct
    38701 acctctacca ggaaaataca acgcgaccaa tgctatggta gcagcctatg taggaaaact
    38761 attggcagta acagacgagg atattatagc tgctttacag actgtgacgt tgacaggtaa
    38821 tcgtacggag tggaaaaaag cagccaatgg tgctgatatt ttatcagatg tctacaatgc
    38881 caacccaaca gccatgcgtc tgattttaga aacatttgct aacatagcaa agaaccccgg
    38941 aggaaaaaag attgcagtgc tagcagatat gaaagaactt gggaaggatt cagtgatact
    39001 tcattctcag ttaattgaca gcttaacatc aggtaatatt gatcagcttg ttttttatgg
    39061 ggatcatatt aaagaattag cacggttggc aagtcaggtt tatcctgctg agcaagtaca
    39121 ttatttttta aaaactgaac aagaagacca gtttgaagcc atggcacaat atgttcaaaa
    39181 cattcttaat ccctttgatc aaattctttt aaaaggcagc cactcgatgt cgctagaaaa
    39241 gttagtggat cgattagtga ctgacaagaa ttgtgatagc tatcagcctt gatttttata
    39301 aaactttcag ataaagtctt gttctctcat gaagattaag gtataatgaa aaaatataga
    39361 aagggacgat tatggatttt tttgcaattg accccatcgg actgcctcat acctcactta
    39421 tcttttactt gtcgtcactc ttgatagcgc ttttgcttgt ttttttgact tttcaagcat
    39481 ataggttaaa atcttatcga tattttttct tgtttttaca gttatctcag gtgattggct
    39541 tgtacacatg gtacgtgtta agggggtttc ctttagatga agctttgccg ttgtatcatt
    39601 gtcgcatcgc tatgttagct atcttttttc tacctgatcg taacaagttt aagcaattat
    39661 ttatggtttt ggggataggt ggaacattcc ttgcactttt atcgccagat ctttatccgt
    39721 ttagattatg gcatgtagca aatgtctcgt tttatcttgg tcattatgct ttgttagtga
    39781 atggtttgat ttacctcttg cgtttttacg atgccagtca gttaagactg ctatcagtag
    39841 tacgctattt agcaactgtt aactttcttc ttctgttggt cagtttagcc acgaaaggaa
    39901 attatggttt tgtgatggat attccagtga ttcatacgcg tcatttgcta cttaattttg
    39961 tgatcgttac aagtggcttg acttttatgg ttaaaataac cgaatatttt taccttaaat
    40021 ttggtgaagc tcaacagctg gcatttgctt tctctaaaga aaagtaggtc gttgaaaaag
    40081 cacttaaaat cagctataat aagaagagtc tgggatgatt tccaggctcg atttttttaa
    40141 aaaagatact cattgatagc ccaagataag ttataatacc agttttgaag aactttagag
    40201 gctaatcgta tatggagaaa cccaatgtag cccaactctt ttgataaaca agtaatacct
    40261 aacgaaaata actcagagaa aagctctgcc attttactat acaaggaaaa aagaatgtca
    40321 cttacagaag aaattaaaaa acgccgtact tttgccatca tctctcaccc ggatgctggt
    40381 aagacgacta ttactgagca actattatat tttggtggtg aaattagaga agcagggaca
    40441 gtaaaaggga aaaaatcagg tacgtttgca aagtccgact ggatggatat tgaaaagcaa
    40501 cgtggtatct ctgttacttc atctgttatg caatttgatt acgcgggtaa acgtgttaat
    40561 attttggata cacctggaca tgaggatttc tcggaagata cataccgtac cttaatggct
    40621 gtggatgcgg ctgtcatggt tgtagattcg gctaaaggta ttgaggcgca aacgaaaaaa
    40681 ctttttgaag ttgtcaaaca tcgtaatatt cctgtcttca cctttattaa caagttagac
    40741 cgtgatgggc gtgagccttt agaactcttg gaagaattag aagaagtttt agggattgct
    40801 tcttatccga tgaactggcc gattggtatg ggacgcgcct ttgagggctt atatgattta
    40861 cataataaac gtttagaact ctataaggga gacgagcgtt ttgcaagtat tgaagacggt
    40921 gatcagctgt ttgccaataa tcccttttat gaacaagtca aagaagatat tgaacttctt
    40981 caagaagcag gtaatgtctt ttcagaacaa gctattcttg atggtgacct aactccagtc
    41041 ttttttggct ctgcccttac gaactttgga gttcagactt ttcttgatac tttcttggag
    41101 tttgccccag aacctcatgg tcacaagact acagaaggta atgttgttga ccccttagct
    41161 aaagattttt caggttttgt ctttaaaatt caagctaaca tggaccctaa acaccgtgac
    41221 cgtattgctt ttgtgcgtat tgtttctggt gaatttgagc gcggtatggg agttaatttg
    41281 acacgcactg gcaaaggcgc taagctctcc aatgttactc aatttatggc agaatcacgg
    41341 gaaaatgtga cgaatgctgt tgctggggat attatcgggg tttatgatac aggaacttat
    41401 caagttgggg ataccttaac agttgggaaa aataaatttg aatttgaacc cttaccaact
    41461 tttaccccag aaatcttcat gaaggtttct ccgaaaaatg ttatgaagca gaaatccttc
    41521 cacaaaggta ttgaacaatt agtacaagaa ggagcaattc agctttataa gaattatcag
    41581 acaggcgaat acatgctggg tgctgtgggt caactgcagt ttgaagtctt taaacatcgt
    41641 atggaaggtg aatacaacgc tgaagttgtg atgacaccaa tgggtaaaaa gactgttcgc
    41701 tggatttcag aagatgattt ggatcaacgc atgtcctcaa gccgaaacat tttagctaag
    41761 gatcgttttg accaaccagt tttcctattt gaaaatgatt ttgcccttcg ctggtttgca
    41821 gacaaatacc cagatgtcac tttagaagag aaaatgtaat cgaaacatga ttttcaacag
    41881 tctaacgttt tggagatcaa tttactgagc aactttttaa aagaaatgag tggctagtta
    41941 tctcttttgc agatttaaga ttctatcaaa aaacgatatc ttcacaactg taagcatatt
    42001 tatgatttag cggataatcg tgaaagcgtg ttattgctta tattagcctt atttcctatc
    42061 tttttgattc taattgtgtt acactagtta ggttgttaat caaacgacga aaattaaaag
    42121 gtttataagg cagcttcgca ctgccttttt agaaaagaga aacaattgaa atttacagaa
    42181 tttaacttat cacaagacat ccaatcagct gttgttaccg ctggttttga gaaagcatct
    42241 cctatccagg aaatgacgat tcctctcgca ctagaaggga aggatgttat tggtcaagca
    42301 caaacaggaa ctggtaaaac agcagcgttt ggtctaccaa ccttgaataa gattcgtact
    42361 aacgaaaata tcatccaagc attggtcatt gcaccaacgc gtgaattggc tgtacaaagt
    42421 caggaagaat tgttccgttt tggacgtgaa aaaggggtta aggttcgctc tgtttacggt
    42481 ggatcaagta ttgaaaaaca aatcaaagcc cttaaatcag gtgcccacat tgtcgtggga
    42541 acaccgggtc gcttgttaga tttgattaag cgcaaggctc ttattttaga tcatgtggaa
    42601 accttaatcc ttgatgaagc agatgaaatg cttaacatgg gattcttgga agacattgaa
    42661 gctattatta gtcgtgtccc agcagaccgt caaaccttgc tcttctccgc aacgatgccg
    42721 gcacctatta aacaaatcgg ggttaaattc atgaaagacc ctgaacatgt tcaaattaag
    42781 aacaaagaat taacaaacgt caatgttgat caatactatg ttcgtgtgaa agaacaagaa
    42841 aaatttgata ctatgacccg tctgatggat gttaaccagc cagaattatc catcgttttt
    42901 gggcggacta agcgccgagt tgatgaaatt acacgtggct tgaaacttcg tggtttccgt
    42961 gccgaaggaa tccatggtga tcttgaccaa aataaacgct tacgtgttat ccgtgatttc
    43021 aaaaacgacc aaattgatat tcttgttgcc actgatgtag cagcgcgtgg ccttgatatt
    43081 tcaggagtta cccacgttta taactacgat attacccaag atccagaaag ttatgttcac
    43141 cgtattggtc gtacaggtcg tgccggtaaa tctggtgagt ctatcacttt tgtctcacca
    43201 aatgagatgg gctacctctc aatgattgag aacttaacga aaaaacagat gaaacctctt
    43261 cgtccagcaa ctgctgaaga ggcctttcaa gccaagaaaa aagtagccct caagaaaatt
    43321 gaacgcgact ttgcggatga gactattcgt tcaaactttg ataaattcaa aggcgatgct
    43381 gtccaattgg ctgccgaatt cactcctgaa gaattagctt tatatatttt gagcttaacg
    43441 gttcaagatc cagatagctt accggaagtt gaaattgcac gtgaaaaacc attaccattc
    43501 aaatatgtgg gtggtggtca cggcaataaa aatggcaaag gtggtcgtgg acgtgacaac
    43561 cgtaaccgtg gtgatcgccg tggtggctat cgtggtgacc gtaacagaga tgagcgtgat
    43621 ggtgaccgtc gtcgtcaaaa acgtgataag cgtgatggtc acgatggcag tggcaaccgc
    43681 gatttcaaac gtaaatcaaa acgtaatagt aaagactttt tcaataaaga gaaaaaatca
    43741 agtgctaaaa atactggttt tgtgattcgt cacaaaggtg aataagctta aagagagttg
    43801 atgagagtca gctcttttta attttctgaa aaagttgctt ttataatggg atctgttata
    43861 atggtttcag ttatttcatt ataattttta aaaaattagg aggagtataa gatgtctgat
    43921 agccatctta ctgcctttga caaagcttca aaagcaggtt ttattattgc tttaggtatt
    43981 gtttatggag atattggaac aagccccctt tatacgatgc agtctctagt tgaaaatcaa
    44041 ggaggggtta atcaggtttc tgaatccttt attttaggat caatctcttt aattatttgg
    44101 acactgacct tgatcacaac aatcaagtac gttttgattg ctctaaaagc tgataaccac
    44161 catgaaggtg ggattttttc tttattcacc ttggtacgta aaatatcacc gtggctcatt
    44221 attccggcga tgattggagg tgcaacactt ttgtctgatg gggctcttac acctgcggta
    44281 acagttactt cagctattga gggcttgaaa gccgttcctg gtctgagtca catctaccaa
    44341 aatcaaacca atgtcattat cacaactcta gtgattttaa tagtcttgtt tggtattcag
    44401 cggtttggaa caggttttat tggtaaaatt tttggaccag ttatgtttat ctggtttagt
    44461 tttctaggtg ttagtggttt ttttaatacg ttggggcatc tggaaatttt caaggctatc
    44521 aatccttact atgctctgca tttgctgttt agtcctgaaa accatcgtgg gatttttatc
    44581 ttggggtcca tttttcttgc gacaacagga gctgaagccc tttattcgga tttaggacat
    44641 gttggtcgag gaaatattta tgtgagctgg ccctttgtta agatgtgtat tgtgttgtct
    44701 tactgtggcc aggctgcgtg gattttagcg aataaacact caggtattga actaaaccct
    44761 ttctttgcta gtgtgccatc acaattaaga gtttaccttg ttagtttggc aaccttggca
    44821 gctattattg cctcacaggc tcttatttca ggctccttta ccttgatttc agaggccatg
    44881 cgtttgaaaa ttttcccttt gtttcgtgtg acttacccag gggcaaattt ggggcaattg
    44941 tatattcctg tcattaactg gattttattt gcagtgacct cttgtactgt tttggctttt
    45001 agaacatcag cccacatgga ggcagcttat ggtcttgcta ttaccatcac catgttgatg
    45061 acaacaatcc tcttaaagta ttacttaatc aagaaaggaa cgagacccat cttggctcat
    45121 ttagcgatgg ctttctttgc ccttgtagaa ttcattttct tcttggcttc agctatcaaa
    45181 tttatgcacg gtggctatgc ggttgttatc ttggcacttg caattgtctt tgtcatgttt
    45241 atctggcatg cgggcacacg gattgttttc aagtatgtga aatctcttaa tttgaatgat
    45301 tacaaggagc agattaaaca acttcgtgac gacgtttgtt ttgacctcta ccaaacaaat
    45361 gttgtctact tatccaatcg tatgcaggat catatgattg accggtctat tttgtactcc
    45421 attttagaca agcggccaaa acgcgctcaa gtttattggt ttgtaaatgt ccaggtaact
    45481 gatgaacctt atacagctaa gtacaaggta gatatgatgg gaacggatta tatggttcga
    45541 gtcaaccttt atcttggttt tagaatgcca cagactgtgc cacgctattt gcgcacgatt
    45601 gttcaggatt tgatggaaag tggccgttta cccaaacaag aacaggaata taccatcaca
    45661 cctggtcgtg atgttggtga ttttcgcttt gttttaatag aagaacgggt caccaatgca
    45721 cgtcaattga gtaactttga acgctttatt atgcagacta aggcaagcat taaacatgtt
    45781 accgctagtc caatgcgttg gtttgggctt caatattccg aagtaaccct tgaagtggtt
    45841 cccttgattc tatcagatgt cttgaagtta ccaatcaaag aattggtgcc tgtggaagac
    45901 agtgaagcat aaaaaaatca ttgagatgat aagtctcaat gatttttctt ttctttttga
    45961 tgagtagcaa tataggccaa tttctggctt cttgtttttc gttttttaaa gagtgcttca
    46021 gcgctcatcg cagcctcttt gctatcaaac acttcgtaat aaagtaaaga aacaggtaac
    46081 cggtagcgag tatatttagc cccctttcct gcgttatgtg tagctaaacg ctttttcaaa
    46141 tcagttgtat aaccagtgta gagggtttta tctgcacatt ctaacacata catataagct
    46201 tttttagtgg tcatgattag gttttccttt ggaagcagca ccaaaataaa tctcaaaaat
    46261 atgatcagtg tattctccgt tttccttgtg gacaactaaa ggaggtaaaa tagtcatccc
    46321 ttcaatagaa ccgtctttga ttgcttcaat aagtaacata ttagctgatt tacctaattt
    46381 aggatagaca aattgtaccc ttttaggggc aagaccatta gctctaaggc tatctataat
    46441 ttccaagaat cgatctggtc gatgaaccat tgccagacga ccatttgatt taagggcatg
    46501 acgggctacc tgacaaatct cttctaaatt agtggtcact tcatgacgag ccagtaaata
    46561 atgttcagag acgttcttct tagaactttc gtgactttta aagtaagggg gattgcagag
    46621 catcaaatca actcctgaac gtggcacatg gtttaggagg ttttttaaat catcacaaat
    46681 catggttact tggtcttcca gttgattgag ctggatagag cgttgtccca tatcagcaag
    46741 ccgttcttgt aattctactt caacgatggc tgccttggtt ctagtgctag caaataagcc
    46801 aaccgcccca tttcctgagc acaaatccac aattaaccct ttggaaggca tcttggggaa
    46861 gcgggataag aggacgctat caatagagta actaaagaca tccttgtttt gaataatgcc
    46921 aacatcactt gaaaagagtt gatcaatacg ttcgccttct tttaagattg cttttatcat
    46981 acctgttatt ttaacataaa ataggcttga ggtgaatgtt tgaagagtga ttttgacttt
    47041 cgaaaagtca gctttcatga tacaataagt aagattattc tattaaagga gaagcctgtg
    47101 ttttacgctt acttacgcgg tttagtagtc tttttattat gggttgtcaa tggcaatgcc
    47161 cactaccatc atgaagaaaa gatgttagat gcttctgaga attatattct ggtagcaccc
    47221 catcgaacct tttgggatcc agtttacatg gcatttgcag cacgtcctaa gcagtttatt
    47281 tttatggcta aaaaagagtt gtttgcaaat cgtctctttg cttggtggat taaaatgtgt
    47341 ggtgcttttc ctattgatcg tgacaaaccg agtccagatg ctattcgtta ccctgttaat
    47401 atgctcaaaa agagcaatcg ttctcttctt atgtttccaa gtggaagtag gcattcgcaa
    47461 gaggtcaaag gaggggtcgc tgtgattgct aaattggcta aggtcaagat tatgccagca
    47521 gcctatcagg ggcctatgtc ggtcaaggga ttactagcgg gagaacgggt tgacatgact
    47581 tttgggaatc ccattgacgt ctcagatatt aaacgcatga atgatgaagg gattgctgag
    47641 gtggcaaacc gtattcaggc agagtttgat cggatggatg acgagttggc acctttccaa
    47701 ccaggaaaag caaggaaccc tttaacttat ctctaccgtt taccattagg attggttttg
    47761 gtggtggtat tattattaac catattattt tcctatattg ctagttttgt ttggaatcca
    47821 gataaacatc gccattaaga acatgagggc taacatgtgc ctgaaataag aagtgattga
    47881 gattagtctt ctattgaaag aagccgctaa tgcttaatca cttttttcat ttctaaaaaa
    47941 gatattcgat gataccctta actcttttaa gcacaaaaaa tgacaatact actatacttt
    48001 tggatatcat ttacgaataa aaagatgagg taaaaaaatg ttagacgaat tattaattaa
    48061 aggaaaatcg tttttgagag agcggtattt tctgccatac ctaattagtc ttttattagg
    48121 actttttcta atactaagct tcagtttttt gttctgggga aataggcaga gcaaggcagc
    48181 cgttcctgct ttgagagaaa tatcgcctgt gaaacagcag gttagtgaag aaaaaaagga
    48241 aattcaagaa gatagcagta ttttagtgga tttaaaaggc gccgtacaaa aagagggagt
    48301 ttataagcta actgctagca gtcgtgtgcg agatgtcatt gaactagctg gaggcctaac
    48361 ttcagaagct gataaacatg ctattaattt tgcagaaaaa ctaactgatg agcaagttgt
    48421 ttatgtacct aaacaaggag aagagatttc tgtgctacca agatcattag tttctggtaa
    48481 aaaagaaact gccagcaagg atcagtcaaa ggttcatatt aataaggcca gcttagaaga
    48541 actacaacat atcccaggta ttggtgctaa aagagctcag gatattattg atatgagaga
    48601 taagttaggt ggttttaaag cgttagaaga tctccgtcag gtttcgggga ttggcgaaaa
    48661 aacgctcgag aaattaaaag atgacatttt cttggactaa gctagtgccc ctgtcaaaga
    48721 ttcaatttgc ttttttaatc ttggttctct tttatcaaat ccatagccct agctggttaa
    48781 cgtttctcct tagccttagt ttgatttgct tacttgtcaa gcgtttgtct aaaaaagaat
    48841 ttctcggtgt ctttgccatc cttagtttct gtgctttgtt tttgctgtat cagaaacagc
    48901 agttgattca aaaactggaa attcagccag tacaaataac ctctgtagca ttagttcctg
    48961 atagtattcg gattaatggt gatcaattac tgttcttgga cgtcacggga aacattctta
    49021 tcagttattt taccgtttga aaagccaagc agaagcccaa ttgttcaaga aagagcaccg
    49081 ttggttagtg atgcacgcaa aagtgacatt ggaaaaagct gaggaagttc gaaattttaa
    49141 aggctttaat tatcagactt ttttggctta tcaaggaatt tacaggatag ggaaggtaga
    49201 gcaaatagaa cagcttgaag tgatttcacc cgagtcaata tgtgactatt tgtcctcttt
    49261 aagacgacga gccattgttc attgccagca gcattttcca agacctatgt ctcactacct
    49321 gacgggcctc ctttttggtt atttagataa gtcgtttggt gagatgacag attattatag
    49381 tcagttgggt atcattcatc tctttgcttt atcagggatg caggttggct tctttcttac
    49441 ttgttttaga agggtgttgc tattactcgc agttcctttg gaatggataa aatggataga
    49501 gcttcctttt gcttgctttt atgccgcgtt gacaggttat agtatttctg ttattcgaag
    49561 cctcgtgcag tcgcagttgc gtcatttagg aataaaagga ttagacaatc tggcttgtac
    49621 ttttttactt gtctttttat gggatgctca tttcttaatg actgttggtg gcgtattaac
    49681 gtttagctat gcttttttgt taacagtggt tactgttgaa gaattatcag gagctaaaag
    49741 acagttggta caagtcttga ccatttccct aggaatatta ccatttttgc tcttttattt
    49801 ttctagtttt aaccccatgt caatggtctt aacagggctc ttgtcttatc tctttgacct
    49861 ttttattttg ccccttcttt gtctggtttt ttgtctatcc cctttggtga ctgtctcaat
    49921 atgtaaccat ctttttattt tattagaaaa agtcattcaa tttctcggaa atactttcaa
    49981 tagttccctt gtttttggaa gcccgaccag ttggcacttg cttatcttgg tgattagctt
    50041 cgctattttt tatgattatc ggcaggtgcg acaacgagtt atcacttgcg gtttggttat
    50101 agcgttgacg cttttgtctg tcaaatatcc tttgaccaat gaagtgacct ttatcgacat
    50161 tggccaggga gatagtattt tggtgaggga gtggacaggg aaaaatctct taatagatgt
    50221 aggtgggcgc cctttctttt cttcaaaaga gcactggcga cgaggacatc acgtagctaa
    50281 tgctcagaaa accttaattc cttacttaaa aagtagaggt attcacacaa ttgaccaact
    50341 attagtaact cacgcagata ctgatcatat gggggatatc gaagtggttg ccaaagctat
    50401 tcgaataaag gagattttga ctagtcaagg cagtttaagc catccaagct ttgttaggcg
    50461 gctaaggcgt ttaaaatgtc acgttagggt tttagcagct ggagaccagt tgcctattat
    50521 gggaagtgtc ttacaggtac tctacccttg gcagttaggg gacgggaaaa ataacgattc
    50581 tttggtactt tatggcaggc tcttaaatcg aacttttctt ttcacaggtg acttggaaaa
    50641 agagggggaa aacgagatca taaaacgtta tcctcaacta agagtagatt atttaaaagc
    50701 aggtcaccat ggatcaaata cctcttctag tgcagctttt ttagaccata ttcagcctaa
    50761 agtggccttt atttctgctg gaaaaaataa ccgttatcag catcctcaca gagaaacctt
    50821 agcccgtttg gaagacagac aaattactta ttaccgaacg gatacgcaag gagctattcg
    50881 tttgactggt tggacaagct ggcatcttga aacggtccgt tagttaaaat tccagcctga
    50941 cgaagaaaca agcagtcgct ttccttttag gagaaagatg atataataaa agcatgattg
    51001 cgatagaaaa gattgaaaaa ctgagtaaag aaaatttggg tcttataacc cttgtcacag
    51061 gagatgacat tggtcagtat agccagttga aatcccgctt aatggagcag attgcttttg
    51121 ataaggatga tttggcctat tcttactttg atatgtctga ggccgcttat caggatgcag
    51181 aaatggatct agtgagccta cccttctttg ctgagcagaa ggtggtcatt tttgaccatt
    51241 tgttagatat cacgaccaat aaaaaaagtt tcttaaaaga aaaagaccta aaggcctttg
    51301 aagcctattt agaaaatccc ttagagacta ctcgactaat tatctttgct ccaggtaaat
    51361 tggatagtaa gagacggctt gttaagcttt tgaaacgtga tgcccttgtt ttagaagcca
    51421 accctctgaa agaagcagag ctaagaactt attttcaaaa atacagtcat caactgggtt
    51481 tgggatttga gagtggcgct tttgaacaac tgcttttaaa atcaaacgat gattttagtc
    51541 aaatcatgaa aaacatggct tttttaaaag cctataaaaa aacgggaaat attagcctaa
    51601 ctgatattga gcaagccatt cctaaaagtt tacaagacaa tatttttgac ttaaccagac
    51661 ttgtcctagg aggtaaagtt gatgtggcta gagatttgat tcatgattta cgcttatcag
    51721 gggaagatga tattaaatta attgctatta tgttggggca atttcgctta tatttacagc
    51781 ttgccattct tgctaaagaa ggaaaatcag aacagcagct tgtaaccagt ttgtcagaga
    51841 tacttgatcg gcgggttaat ccttaccagg tcaagtatgc gttaaaggat tctaggacct
    51901 tatctcttgc ctttctaaca ggagcggtga aaaccttgat tgagacagat taccagataa
    51961 aaacaggact ttatgagaag agttatctag ttgatattgc tctcttaaaa atcatgactc
    52021 actctcaaaa ataggcgttg gaccgctttc caagagataa tcaaattagt tgaaagctct
    52081 tattttttgc gataagatag acgtatcata aaggaaaaga ggacaggaaa atggctatta
    52141 ttttaccaga acttccatac gcgtatgatg ctcttgaacc acagtttgat gcggagacaa
    52201 tgactcttca tcatgataaa caccatgcca cttatgtcgc taataccaat gcggctttag
    52261 aaaaacaccc agagatcgga gaaaatctgg aggaactatt ggcagatgtc actaagattc
    52321 cagaagatat tcgtcaagcc ttaattaata atggtggcgg acacctaaac catgcgcttt
    52381 tctgggaact attatcacct gaaaaacaag acgtcactcc tgatgttgca caagccattg
    52441 atgatgcttt tgggtcattt gacgccttta aagaacaatt tacagcagct gctactggac
    52501 gttttggttc aggttgggca tggttagttg ttaataaaga aggacaactc gaaatcacat
    52561 caaccgctaa ccaagatact ccaatttcag aaggcaaaaa accaattcta gcgcttgatg
    52621 tgtgggagca tgcttactac ttgaattatc gtaatgtacg tccaaattat atcaaagctt
    52681 tctttgaaat cattaattgg aaaaaagtat cagaacttta ccaagccgct aaataagaaa
    52741 agggtttcca atctcaaaaa gagattggtt ttttaagtgg ttttgtgaat aacagtgtgg
    52801 ggacatcatt ttttagaaaa gataaaaata gtttgtcttt ttaatgtaat tccttgattt
    52861 ttagctaaat ttagctagaa tagaatggat aggagatttt aggtgttaag aaagaagaaa
    52921 actaccattg tagggattat tttaggaatg atgatagtga ccttacttgt cggctgtttg
    52981 actggtaaaa agaaaggctt tcctcctaaa gcaggtgagc ggcagcaaac ggctgactta
    53041 aaaatgaaaa aagattagaa aaactgttca aaaaccgtta cctgaaaaat ctaaagaggc
    53101 taagcaagct gttatggatg cagatttagc gcaaatggat gccttagggc tctattacga
    53161 tgacaaccat ttgagtttgg tcaatacggt caaggtgtat ttaaaggaat ttggcattgg
    53221 tgaatctcaa attgcctttt cctacaaaga cctcaattca ggcaggactg ctgccatgaa
    53281 tgaccatcag ccaatgattg caggaagcac ctataagctg ccattaaaca tgctggtggt
    53341 agataaggca aattatccat gacagagcgt tttgacatta cagaaactga ttatgaatat
    53401 gatcaggaac atcatgccta tgttgctcaa ttcaatggtg ccatgtctat tccggatatg
    53461 caagaatatt ccttggtgta ctcagaaaac acgccagctt atgctctagc agaacgattg
    53521 ggtggcatga ataaggctta ccaattattt gaccgctacg ggaaggtatc cggagctatt
    53581 acgaccattg atcgtaatgg caataaaatc accaccgctt actatttgca aggtttggat
    53641 tacttgtggc agcatcagga taaatataag gatatcttgt actacattgg tgaatctttc
    53701 cctgatttgt attacaagac ttatttgcct catgtaaagg tttatcaaaa accgggttat
    53761 gtcagagaag ccttaaatgt aggtgccatt gtttgcgaag agtctcctta tttgattact
    53821 ctttattcat ctggtttagg tggagcaaca caagcatcag aggaagtcaa tggccttggt
    53881 tatgtgcagc ttgttcagct aacatatgta attaatgagt ggcatagagt caatcacaac
    53941 atgatctaat actcagttga cattagtctg atagtagaca tacttactga tgaaagtcac
    54001 taaaataagt ttttgctcat taaaaaagct tggcctgttt cttcaggtca agctttttga
    54061 gattaatgct gtgtttttga ggtcttattg tcacctcttg tttcttgata atggtgaagc
    54121 aattttttga attttttaac ggcagcgcgt gttagctgct tagatgattt gccatttctg
    54181 ctgtaaatgg gattgtgctt atccctttgc tgttctaaat cgggaactag aaaagttgca
    54241 tcaggactat taattgcttt ttcaataaaa gccggatcaa aaagcagaat agggtcaata
    54301 tcaagcagac ggtgcaagtc atcgttttgg ttgccataat tgaaagaaga accattgaca
    54361 atactatttc gcgttaggtt atcaggatct agtgctacta aaaattgtcc agattctgac
    54421 aaaataaact ctgagtgaaa atgaattaaa atcttatagt tggcttgagg aatattgtct
    54481 gtatagactg cctgatgatt gccattagca tctaaaatac tagcaacctt attatggtat
    54541 ctagaagatt cataaagagc ataatcgtca tcttctagag tagccaaata tttggctaag
    54601 gcatccgcat cggttttccc tttattccca taatgtgagc gaacccactc cgtttgctgg
    54661 gttgatatga ggtaacggag ttgatgaatt ttccgattag aacggctata aggaatgtgt
    54721 tcgagattaa cataataagc ctgaatcagg gtagataatt ggtcccaaaa aggatctgtt
    54781 ggcgatagct ttggacttaa ttgtgccaat acttgctgtg tttgttttga ttgtcctgtc
    54841 aactcgtctg gcatctttaa atacgtcaag agcagttgta accgcttttg agcttcttga
    54901 ggcgtctgtg ccatctcttc ttgttgccaa agcttttgaa agtcaggtga tcctatcagg
    54961 cgaatgcgac tataaagttg ttcgaaatga taagagtttc ctctaacagc gagttgttca
    55021 aggtatcctt tttggatggc tttataggac catccgtcct tatcgagctt tcgaacataa
    55081 tcaagcaagt cgtggcgtaa tttaatagct tctgaaagct ggagttctcg taatttagga
    55141 tagttttggt aaaaaggtgc cactaaattt tgataaagtt tgtgttcttt ttcaaaggca
    55201 atccgctgat agtctttctg ccaaaaactg acgcaaaaag tcagaaacat caagaagaat
    55261 agccattttc caagtaattt cataggtttt tagttgacaa acatggcatc gccaaagcta
    55321 aagaaacgat acttttcgtc aaccgcgtgt ctgtaagctt caaggacaaa gtcacgccct
    55381 gcaaaggctg atactagcat cacaagggtt gattttggaa gatggaaatt agttgaaaaa
    55441 gcatcaacta ccttgaattg gtagcctggt ttaataaaaa tattggtcca acctgaatca
    55501 gcttgaatgt ccccttggaa cttacctccg atggtttcca acgtacgaat agaggtggtt
    55561 cctacagcga caacacgacc gccagcttgt ttgacgtctc ttagggtttg cgctgcttct
    55621 tctgagaggg aataaaattc cgaatgcata tcatgctcat cgaggttatc cacggaaaca
    55681 ggtctaaaag tcccaagccc tacatgtagg gtcaaataaa ccaaatgtac ccctttggct
    55741 tcgatttttt tgagcaagtc tgttgtgaag tggagaccag cagttggggc ggccgcagag
    55801 ccattttctt tagcataaac ggtttggtat cgctcagcat cctctaattt ttcgtgaata
    55861 taaggaggca atggcatttc gccgaggctc tctaaaactt ctaagaaaat cccatcatag
    55921 ctgaattcaa caattcgtcc accatgttct aattcgtcga taatggtggc tttgagacgc
    55981 ccatctccaa aattgacttg gctaccaacc ttgagccgtt tggctggctt ggctaaaact
    56041 tcccattgat ctccttgtgt atttttaagc aaaagcaatt ccacatgacc atgagtatcg
    56101 ggtttttctc cataaagtct ggcaggcaag acacgggtgt tattcatgac gagggcatcc
    56161 cctggattta attgatcaat gatatggtca aaatggctat caaccatagt tttttgacgg
    56221 tgatcaataa tcaatagttt tgaactgtct cttttttcga gtggggtttg ggcaatcaat
    56281 tcttctggta actcaaaatc aaaatcgtta gtattcattg ggactccttt aaagccacta
    56341 gtaaatctct tcctagtaac tctttcatgt aagataaatc ttttctatta tatcacttgt
    56401 cgtctaaccc gtcatcttta atctttcatc agaaagtaaa ggataggctt gacaaaaatt
    56461 ggtatatacc atataataaa aacacgaaag gtctatacca attagaaaag gagaatgaca
    56521 tgaaaattat tcgggtccaa gatcagattg aaggtgggaa aatcgctttt accttattga
    56581 aagatagctt agctaaggga gctaagacgt taggattagc aacaggaagt tcaccaatta
    56641 gtttttacca agaaatggtc aaaagtcctt tggatttttc ggacttaaca agtattaact
    56701 tggatgaata tgtcggtctt tcagtagaga gcgatcagag ttatgattat tttatgcgtc
    56761 aaaacctttt taatgcgaag ccttttaaaa agaattactt gcccaatggt ttagcaactg
    56821 atatcgaagc tgaagctaaa cgatatgacc aaatcattgc agagcatccg attgattttc
    56881 aagtgcttgg gattgggcgt aatgggcaca ttggttttaa cgaacctggg acctcttttg
    56941 aagaagaaac gcatgtagtg gatcttcagg aatcaactat caaagccaat agtcgtttct
    57001 ttacaagtat tgaggatgtg ccaaaacaag ctatctctat gggaattgcc tccatcatga
    57061 agtccaaaat gattgttctt cttgcctttg gacaagaaaa agctgatgcg atcaagggaa
    57121 tggtttttgg accaatcaca gaagacctcc cagcaagtat tctccaaaaa catgatcatg
    57181 ttatcgtcat tgtggatgaa gctgctgcgt cacaattaga ttaacctaac cagtcgttaa
    57241 accttgtaag aacaaaaatg aggagatagt caacctcatt taagaagaag tcttgtaact
    57301 tctatttctt ttgcaagggt aaatttatgt tacactacta atatgcgttt agataaatta
    57361 ttagaaggta caaaagttgg ctctagaagt caagtgaaga aactgattaa ggctcaaggg
    57421 gtttgggttg atcacatgcc tgccagaaat ggtcgacaaa atgttgatcc tggcttgcaa
    57481 ctgattgagg tgactggaca gcgagtgacg catcctaaac attcctacat tatcctcaac
    57541 aagccatcag gggtggtctc agctaagaaa gatactaact atttaaccgt tattgatcag
    57601 cttgctgaag aagataaaag tccagacttg tatcctgttg gcagattgga tagagatacc
    57661 gaagggttgg ttttactcac tgataatggt cccctagggt ttcggatgtt gcaccctatt
    57721 catcatgttt ctaaaacgta tcttgtaacc gttaatggct tgttagcaga agatgcctca
    57781 gatttttttg cagctggtat ttgtttccca acaggtgaac aatgtcaacc agctcaattg
    57841 actattctta aagccgacac agaccagtca caggctagtt tgaccatttc agaaggaaaa
    57901 tttcaccaag tgaaaaaaat gtttttgacc tatggtttga aagtgacctc tctgaaacgg
    57961 acgcactttg caggattgga actcggtcat ttagccagcg gagaatatcg ttatctaaca
    58021 gcgtcagaaa ggcaactcat taaaacgtat ctagactgag caaaacatgc tttcaaaaag
    58081 aagctattct tgcttaatca ataaagtgtc cattgactat tatagtcatg atgagtccga
    58141 cttttgctat gtttagtcat cttgttgtta caaaatcagg taagcaaaaa aattcaattc
    58201 ccactgtctc cttaacctga agcgttataa aaacccttgt gttaaactct cataaattgg
    58261 aaatgggagt gttttttgat ggctaaaaaa actaaagcta cttaaagttt ggtacttagt
    58321 tttcgaataa taaggtggaa gatctaatag gaggtgacaa aaatattaac cgctttagat
    58381 ggtaagaatc agctcatttc gctagtaact cagcctattt caacgaaacc gcctttttgt
    58441 tgcccagctt gcaaatctcc tgttcgcttg cgtcagggga caattagacg acctcatttt
    58501 gcccatgtac aactagctca ttgtcaattc caagcagaaa atgaatctga ggaacatttg
    58561 acgttgaagg caaaacttta caccagttta gtccgaacag aagctgtctg tattgaaaaa
    58621 tatcttcctg agctgcaaca gatagcagac ctttgggtga atgataagtt agccttagaa
    58681 attcagtgca gtcccttgcc agtggagcgt ctaaagaaac gcaccaaagc ctatcaagaa
    58741 aaggggtatc cggtacgatg gttactggga agaaaattgt ggcttaacac tcacttaact
    58801 gctttgcaaa aacagtttct ttacttttca tctagtttgg gctttcattt gtgggagctg
    58861 gatgcagctg caaatctgct acgtctcaaa tatttaatcc atgaagactt atttggtaag
    58921 gtaagttatc taaccaaaac catttcttta gaccacaata ttatggaaat gtttcgatta
    58981 ccctatcagc aagaaatcct ttattcttat cagaaaaaaa tgactgtgaa cctatctaaa
    59041 agaatacaaa gagctctttt agctagacac ccgaaatggc tacgacgaca agaaaaggct
    59101 tacttatcag gctataattt acttatgtta acaactgatg ctttttatcc tcaatggaga
    59161 ccagttcaat cttccagcgg tttttgtcaa attaaaggaa atcttcgccc ttattatgaa
    59221 agttttaaag tctattataa aaaagaaaag gataagaagg tgcaaacgct tttttcacca
    59281 aaatattatg ttaaaatgga tagtaataga aaatgagaag gagatgttat gactgataat
    59341 cgcagccatt tagaagaaaa atacacttgg gatttgagca ctatttttgc aacagataag
    59401 gattgggaag ctgaagtcag tgacttagct actgaaattg acgcggctaa ggatttttca
    59461 ggtcatttac tagattctag cgctaatctg ttgacaatta cagatactta tttagagtta
    59521 gctcgtcgtg ttgagaaagt ctatgtttat gctcacatga aaaatgacca agacactact
    59581 gttgccaagt atcaagaata ccaagctaag gcttcaggct tgtatgcaaa gtttagcgaa
    59641 gtgttttcat tctatgaccc agaagttatg gcattgagtc aggaagatta ccaagctttt
    59701 cttgcggaaa cacctgattt aaaaaggtat catcatttct ttgacaaatt gttccagaca
    59761 cgtgaccatg tgctcagcca ggctgaagag gaattattag caggagccca agaaattttc
    59821 aacggcgctg aagaaacctt tagtattctt gataacgctg atattgtctt tccagtagtt
    59881 aaaaatgata agggggaaga tgttgaatta acccatggta acttcattag cctaatggaa
    59941 tctaaggacc gtagcattcg ccaagctgct tatgaagcca tgtatagtac ttatgaacag
    60001 ttccaacata cttacgctaa aaccttgcaa accaatgtga aagtgcaaaa ctataaggcg
    60061 cgtgttcata aatacgattc agcacgtcaa gctgccatgg ctgctaactt tattccagaa
    60121 gctgtttacg ataccttgtt agaaacggtt aataaacatt tgccactctt acaccgttat
    60181 ttgaaattgc gtcaagaggt tcttggttta gacgatttga agatgtatga tgtttacaca
    60241 ccattatctg aaacagattt agccattggt tatgatgagg ctttggaaaa ggctgagaag
    60301 gttttggctg tttttggtaa ggattacgcg gatcgtgtac atcgtgcttt taccgaacgt
    60361 tggattgatg ttcacgtcaa taaagggaag cgctctgggg cttattcagg tggttcctat
    60421 gataccaatg ccttcatgct gttgaactgg caagatacac ttgataatct ttacacactt
    60481 gtccacgaaa caggccacag tttgcattct actttcactc gtgaaacaca gccttatgtg
    60541 tatggggatt atagtatctt cttggcagaa attgcatcca caacgaatga aaacatcatg
    60601 acagaagctc tcttaaatga agtgcaagat gagaaagaac gctttgccat tttaaaccat
    60661 tacctcgatg gtttccgtgg aacagttttc cgtcaaaccc aatttgctga gtttgaacat
    60721 gccattcatc aagctgatca aaaaggagaa gtgttaacaa gtgaatacct taaccagcta
    60781 tacgctgatt taaatgaaaa atattatggt ttaagtaaaa aagataatca ttttattcag
    60841 tatgaatggg cacgtattcc tcatttctat tacaattatt atgtttacca atatgcaaca
    60901 gggtttgcag ctgcaagcta tttagcggat aagattgtgc atggcacaca agatgatatc
    60961 gatcattact tggcctacct caagtcagga aattctgatt acccacttga agtgattgct
    61021 aaagcaggcg ttgatatggc aaaaggtgat tatttggaag ctgcctttaa agtctttgac
    61081 gaacgtctaa cagaacttga agtactcgtg tccaaaggca tacacaaaag ctaaaatcac
    61141 aaaagtcaag gacaaaaaga gtttaggatt gatagaaatg gagattcaca gttggtgtga
    61201 atctccattt ctatcggtca ttttcttttt atattttagt ggattatcag tcctgaaaag
    61261 caggcttcat tgaccttagt ttgacggttt cttttttgtc ttttttattg tgtggtcact
    61321 cacttaaata aaaccaatag ttgagtaagg cgcttcagat taacgccatt ccattgtttt
    61381 agagataacg ttcgtataaa acgtgttttt attatatttg acattttata aaagagat
//
LOCUS       DATWVB010000008        58730 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.008, whole genome shotgun sequence.
ACCESSION   DATWVB010000008 DATWVB010000000
VERSION     DATWVB010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58730
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.008"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..581)
                     /locus_tag="VCX65_000532"
     CDS             complement(<1..581)
                     /locus_tag="VCX65_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEP5053014.1"
                     /translation="MKKTKLIFSFTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEY
                     SDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKAGDRIAVFSVPFDWNYL
                     SKGKVTAYTYGGITPYQKTSIPKNIPVNLWINRKQISVPYNEISTNKTTVTAQEIDLK
                     VRKFLISQHQLYSSGSSYKSGKLVFHTNDNSDK"
     gene            complement(830..1336)
                     /locus_tag="VCX65_000533"
     CDS             complement(830..1336)
                     /locus_tag="VCX65_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEP5053015.1"
                     /translation="MKIAIIGHSGSGKSTLARFLGQHYHCEVVHLDQLHFSSNWQERS
                     DHDMIADLSTCLLKQDWIIEGNYANCLYEERMSEANHIIYVNFSRFHCVYRAFKRYLN
                     YRGKTRPDMADNCQEKFDVAFVKWILLDGRSRNQLKKYQSVIQKYPHKTIVLTNQKQL
                     NHYMNTIN"
     gene            complement(1391..1831)
                     /locus_tag="VCX65_000534"
     CDS             complement(1391..1831)
                     /locus_tag="VCX65_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP5053016.1"
                     /translation="MKIIEYKGNYRDDLIFMVLEAKNALRRIPSINPDLLTIETSYLE
                     KGDCFWLAVNEESRVIGSIAYSSIPKTNEVFLHRLFIKPSLKHQGIGSQLLTFAEDYL
                     RKIGKSHVRIHLGQPKEQWFESYRFYPKHGYQFYDDTHLIKKLI"
     gene            complement(1972..2044)
                     /locus_tag="VCX65_000535"
     tRNA            complement(1972..2044)
                     /locus_tag="VCX65_000535"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2009..2011),aa:Lys,seq:ctt)
     gene            complement(2045..2241)
                     /gene="ssrS"
                     /locus_tag="VCX65_000536"
     ncRNA           complement(2045..2241)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VCX65_000536"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(2330..3598)
                     /locus_tag="VCX65_000537"
     CDS             complement(2330..3598)
                     /locus_tag="VCX65_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEP5053017.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDSSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            complement(3631..4197)
                     /locus_tag="VCX65_000538"
     CDS             complement(3631..4197)
                     /locus_tag="VCX65_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEP5053018.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANA
                     LVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGNLRLAKRVMHGRQ
                     STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            complement(4230..5987)
                     /gene="pabB"
                     /locus_tag="VCX65_000539"
     CDS             complement(4230..5987)
                     /gene="pabB"
                     /locus_tag="VCX65_000539"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEP5053019.1"
                     /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIENVQHYQ
                     QLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDGITIP
                     NQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQA
                     AGYNAYIAHDDFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQTGSVCVDRLCEVERYSTVWQMTSTIVGDVKADCDL
                     IDILTALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVKHKKIAFL
                     EQHLNRLKEAATYFAYPYDEKALQKQLSTYLENKDNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN
                     LFVQLGRTLYTPPVVVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLKLTHLDALLAKSQA"
     gene            6188..6658
                     /locus_tag="VCX65_000540"
     CDS             6188..6658
                     /locus_tag="VCX65_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEP5053020.1"
                     /translation="MAKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEVTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKVDFGLEWNAQAFEEGQQGLEEAASYAYPRY"
     gene            6728..7681
                     /locus_tag="VCX65_000541"
     CDS             6728..7681
                     /locus_tag="VCX65_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEP5053021.1"
                     /translation="METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKD
                     RFGELYPDVEQSDMIAIIAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQILRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLIKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG"
     gene            7681..8430
                     /locus_tag="VCX65_000542"
     CDS             7681..8430
                     /locus_tag="VCX65_000542"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEP5053022.1"
                     /translation="MQQYFIKGKAEKEVTITDKDTIKHMFQVMRLADKAEVVLVFDDG
                     VKYLAKVTNSMAHELEIIEALPDQVELPVKVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEHKAEFLKSLSG
                     FDHIFVAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPTEITQFEAAGAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            8787..10973
                     /locus_tag="VCX65_000543"
     CDS             8787..10973
                     /locus_tag="VCX65_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEP5053023.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHESAFLASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGALASGLAFVLINRI
                     TGAFYGVSSAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDHNTQATPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDP
                     AKIGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGAVIPEVNMSQLT
                     SKPTPAKDFKHVTEEVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTHGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIKSAERETTIVVAFTNTTEIQDVTLTSLGAQPAKTKVATVEL"
     gene            11056..11874
                     /locus_tag="VCX65_000544"
     CDS             11056..11874
                     /locus_tag="VCX65_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEP5053024.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPNIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIHVSDILVSAMADETDYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKVADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKITFEGGDAPVVSDHYGLEVTLGWR"
     gene            complement(12268..12750)
                     /gene="nrdI"
                     /locus_tag="VCX65_000545"
     CDS             complement(12268..12750)
                     /gene="nrdI"
                     /locus_tag="VCX65_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEP5053025.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
                     "
     gene            13132..14157
                     /locus_tag="VCX65_000546"
     CDS             13132..14157
                     /locus_tag="VCX65_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP5053026.1"
                     /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAEVSTAAM
                     TKEERQQEIEKIKEDIKKEYPKASEEKFWESSFWGRRYFNEQEYLKSLQSFTEQRLQD
                     IVNLIEKGATKGDKGDAGPKGERGPAGPQGPVGPKGEAGKVGAQGPKGDPGAPGKDGA
                     KGEKGDKGDTGERGEKGDIGATGAQGPQGEKGETGAQGPAGPQGEAGKPGEQGPAGPQ
                     GEAGKPGEKAPEKSPEGEAGQPGEKAPEKSPEVTPTPETPEQPGEKAPEKSKEVTPAP
                     EKPADKEANQTPERRNGNMAKTPVANNHRRLPATGEQANPFFTAAAVAVMTTAGVLAV
                     TKRKENN"
     gene            14409..16628
                     /locus_tag="VCX65_000547"
     CDS             14409..16628
                     /locus_tag="VCX65_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEP5053027.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKTDVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGQDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLMHLTTVVEKIKAVPDVYSVKRTNG"
     gene            16643..17086
                     /locus_tag="VCX65_000548"
     CDS             16643..17086
                     /locus_tag="VCX65_000548"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEP5053028.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     SQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(17184..18506)
                     /gene="ska"
                     /locus_tag="VCX65_000549"
     CDS             complement(17184..18506)
                     /gene="ska"
                     /locus_tag="VCX65_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023611186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HEP5053029.1"
                     /translation="MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLDRPSVNNSQL
                     VVSVAGTVEGTNQEISLKFFEIDLTSQPAHGGKTEQGLSPKSKPFATNSSAMPHKLEK
                     ADLLKAIQEQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQE
                     FLLSGHVRVRPYQPKAVHNSAERVNVNYEVSFVSETGNLDFTPSLKEQYHLTTLAVGD
                     SLSSQELAAIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQ
                     AYGINKKSGQEEKMNNTDLISEKYYILKKGEKPYDPFDRSHLKLFTINYVDVNTNKLL
                     KSEQLLTASEHNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHNDTNRIIT
                     VYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPNDK"
     gene            18846..19694
                     /locus_tag="VCX65_000550"
     CDS             18846..19694
                     /locus_tag="VCX65_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEP5053030.1"
                     /translation="MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQALPDDLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQSLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
     gene            19992..21125
                     /gene="ugpC"
                     /locus_tag="VCX65_000551"
     CDS             19992..21125
                     /gene="ugpC"
                     /locus_tag="VCX65_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEP5053031.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLAIAIPEG
                     QAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            21254..22867
                     /locus_tag="VCX65_000552"
     CDS             21254..22867
                     /locus_tag="VCX65_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEP5053032.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
                     RQPDLNWENEALRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDSEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAEELDVPALKTIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSEAKETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFAKDLTGAQ
                     VIITNTDVDTVFETKHLQPWDAFCLKLKA"
     gene            23065..26562
                     /locus_tag="VCX65_000553"
     CDS             23065..26562
                     /locus_tag="VCX65_000553"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEP5053033.1"
                     /translation="MKKKVNQGSKRYQYLLKKWGIGFVIAATGTVVLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSGDGLQSSSKEAKPVLDSSLANPASIAEHHLRMHFKT
                     LPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQIFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDRDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTRVVGQADL
                     TKSDKGVWRAHLTSDSIKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSVNPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSIAYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYRTKVS
                     DDKVPNKATLIDAVAKYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLLGAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKV
                     SSKTANPSQQKSQTDNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEASSKGLLA
                     AGVALLLLAISLLMKRQKD"
     gene            26677..27051
                     /locus_tag="VCX65_000554"
     CDS             26677..27051
                     /locus_tag="VCX65_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HEP5053034.1"
                     /translation="MRPKEKETSMTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRS
                     SCPYCRRFAPKLAQVATDNQKEVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQ
                     HQRAVCDSSLTPDDILAFLTRE"
     gene            27167..27532
                     /gene="yajC"
                     /locus_tag="VCX65_000555"
     CDS             27167..27532
                     /gene="yajC"
                     /locus_tag="VCX65_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEP5053035.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETSVVN
                     EPAVETVDSTDTDSAIESH"
     gene            27751..28500
                     /locus_tag="VCX65_000556"
     CDS             27751..28500
                     /locus_tag="VCX65_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEP5053036.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNRRQRRFGKV"
     gene            28513..29307
                     /locus_tag="VCX65_000557"
     CDS             28513..29307
                     /locus_tag="VCX65_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEP5053037.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            29380..30639
                     /gene="rseP"
                     /locus_tag="VCX65_000558"
     CDS             29380..30639
                     /gene="rseP"
                     /locus_tag="VCX65_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEP5053038.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLDETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMSDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHA
                     KTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNALKGLITGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            30837..32693
                     /locus_tag="VCX65_000559"
     CDS             30837..32693
                     /locus_tag="VCX65_000559"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEP5053039.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAVTPART
                     DLDRWVVLDKSIASMDDIPKEVLEDIKAELAAWMISGEDTIAYSTESSYAANLEMATN
                     EYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            32947..37344
                     /locus_tag="VCX65_000560"
     CDS             32947..37344
                     /locus_tag="VCX65_000560"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEP5053040.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNSHLPNLVKQFEAFGFGTLTID
                     MVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     AAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQDAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     ILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMGILGNMPEDNQLSLFDDFF"
     gene            37454..37882
                     /locus_tag="VCX65_000561"
     CDS             37454..37882
                     /locus_tag="VCX65_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP5053041.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            38013..38555
                     /locus_tag="VCX65_000562"
     CDS             38013..38555
                     /locus_tag="VCX65_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEP5053042.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANVPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKETKANLLSQAEALLAAI"
     gene            complement(38588..39202)
                     /locus_tag="VCX65_000563"
     CDS             complement(38588..39202)
                     /locus_tag="VCX65_000563"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEP5053043.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(39328..39585)
                     /locus_tag="VCX65_000564"
     CDS             complement(39328..39585)
                     /locus_tag="VCX65_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP5053044.1"
                     /translation="MTQNVCQQNITYTVKERFASYTLEAQANQEVHLNLTLLANRFGT
                     SDRHLKHVLKQPIFQRIIERICFKTCRIADLDALTQLSVNN"
     gene            39711..39866
                     /locus_tag="VCX65_000565"
     CDS             39711..39866
                     /locus_tag="VCX65_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053045.1"
                     /translation="MTMLGYRLSAEVRGSAILPLLAGYLIRQAIAQVYSDLKTASWLF
                     GLASSVA"
     gene            40024..40293
                     /gene="rpsO"
                     /locus_tag="VCX65_000566"
     CDS             40024..40293
                     /gene="rpsO"
                     /locus_tag="VCX65_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEP5053046.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            40646..42706
                     /locus_tag="VCX65_000567"
     CDS             40646..42706
                     /locus_tag="VCX65_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEP5053047.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVTSGPWVFSYLLHELGLPDQTKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRAEVVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKPVNEDEIAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     VKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLFGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTRQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            42699..42983
                     /locus_tag="VCX65_000568"
     CDS             42699..42983
                     /locus_tag="VCX65_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP5053048.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            43010..44389
                     /locus_tag="VCX65_000569"
     CDS             43010..44389
                     /locus_tag="VCX65_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEP5053049.1"
                     /translation="MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGP
                     ILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVPNNEAVTSVAQKILGVETMSILV
                     VGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVDFKGSLLIILGGFLLGAWS
                     AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSF
                     LRNTTISTGLIMVLFYLVATVASVLRNTSVTEELAAGQNPFIFAIKSGLTFAVGVAIV
                     YAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVIIGFASSFVGGLLGM
                     LILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLP
                     VLGKLGFSNTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPNFLSKSQE
                     AINNVSEEI"
     gene            44399..45130
                     /locus_tag="VCX65_000570"
     CDS             44399..45130
                     /locus_tag="VCX65_000570"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HEP5053050.1"
                     /translation="MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGI
                     SSYIGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGES
                     TCPVIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTAGVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICRQKEEVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDDNH"
     gene            45410..47542
                     /gene="pnp"
                     /locus_tag="VCX65_000571"
     CDS             45410..47542
                     /gene="pnp"
                     /locus_tag="VCX65_000571"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEP5053051.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIVAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSILTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKI
                     DEKGRVDASMKALIPRPPKPEKKEEKHD"
     gene            47535..48287
                     /locus_tag="VCX65_000572"
     CDS             47535..48287
                     /locus_tag="VCX65_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEP5053052.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSVALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQESAQSQYWLERSALAVLEEVITSGAAGLVFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDNNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            48296..48877
                     /gene="cysE"
                     /locus_tag="VCX65_000573"
     CDS             48296..48877
                     /gene="cysE"
                     /locus_tag="VCX65_000573"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEP5053053.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTVRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            49356..49586
                     /locus_tag="VCX65_000574"
     CDS             49356..49586
                     /locus_tag="VCX65_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053054.1"
                     /translation="MNKIRVGLYVIMSLSILVSSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            49614..50957
                     /locus_tag="VCX65_000575"
     CDS             49614..50957
                     /locus_tag="VCX65_000575"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEP5053055.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKAIHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLEVDIEALIAKRQEARANRDFAIADAIRDQLAAQGIKLLDTKDGVRWLRD"
     gene            50950..51363
                     /locus_tag="VCX65_000576"
     CDS             50950..51363
                     /locus_tag="VCX65_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEP5053056.1"
                     /translation="MINPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            51559..52356
                     /locus_tag="VCX65_000577"
     CDS             51559..52356
                     /locus_tag="VCX65_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053057.1"
                     /translation="MTTMQKTVSLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASIRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMAAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAT
                     TNSVDVDTKAQTNQSANQEIDSTSNPFKSATNHRSTSLKRSTKNEKLTPTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLSGLVVSLAAGLFIAIQKVSRRK"
     gene            52403..53149
                     /gene="rlmB"
                     /locus_tag="VCX65_000578"
     CDS             52403..53149
                     /gene="rlmB"
                     /locus_tag="VCX65_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEP5053058.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            53153..53671
                     /locus_tag="VCX65_000579"
     CDS             53153..53671
                     /locus_tag="VCX65_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEP5053059.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKINQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     IQLKDFMSQLDR"
     gene            53768..54628
                     /locus_tag="VCX65_000580"
     CDS             53768..54628
                     /locus_tag="VCX65_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP5053060.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            54764..55462
                     /locus_tag="VCX65_000581"
     CDS             54764..55462
                     /locus_tag="VCX65_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053061.1"
                     /translation="MFDSKQNLAKSQWGFIVITAVMDLVVIVATLLAKTSFQRYLVGG
                     VAVILTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPRYDERQKQILLKGYT
                     IGFWFMIVAVWLSIFLHRFSERLVSASFLFTLALWGGLAVQTTYCNLNGVSPFVDRRF
                     GKQGILVGMIATGMSLITIGLAVREMMAGQLKMGSFFKAGGSGSLMVLGITLLSMGAS
                     IFYRHYLDAKEADE"
     gene            55459..55665
                     /locus_tag="VCX65_000582"
     CDS             55459..55665
                     /locus_tag="VCX65_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5053062.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEVDDSH"
     gene            55883..56329
                     /gene="rplM"
                     /locus_tag="VCX65_000583"
     CDS             55883..56329
                     /gene="rplM"
                     /locus_tag="VCX65_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEP5053063.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            56350..56742
                     /gene="rpsI"
                     /locus_tag="VCX65_000584"
     CDS             56350..56742
                     /gene="rpsI"
                     /locus_tag="VCX65_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEP5053064.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(56875..57024)
                     /locus_tag="VCX65_000585"
     CDS             complement(56875..57024)
                     /locus_tag="VCX65_000585"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053065.1"
                     /translation="MIEIGVDPVNTAKRLGHASSQITLDTYSHATAVGEDKSIKQFAN
                     YLKNN"
     gene            complement(57060..57422)
                     /locus_tag="VCX65_000586"
     CDS             complement(57060..57422)
                     /locus_tag="VCX65_000586"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEP5053066.1"
                     /translation="MAALRKGELCALKWANIDFQSETLSVNKSLGRLDGQAIEKSTKN
                     DFSVRKIKLDSETISILQEWKAISQKEKAQLAVAPLSIESDFIFTYCTREGSIEPLHT
                     DYINNILSKVIKQHSLKK"
     gene            complement(57385..57879)
                     /locus_tag="VCX65_000587"
     CDS             complement(57385..57879)
                     /locus_tag="VCX65_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
                     /protein_id="HEP5053067.1"
                     /translation="MYLKASGNLEEFTKPTHKTYSEIFEEWYQAYQDTVEPTTASRTL
                     DLFQLHILPVMGELPINKTSPLDCQNFITDKAKTFKNIKQIKSYTEKIFDFAIKMKLL
                     KHNPMAEIIMPKRKKTRIENYWTVQELQEFLAIVLQKEPYKHYALFRLLAYSGLKERR
                     AMRS"
     gene            complement(58007..58342)
                     /locus_tag="VCX65_000588"
     CDS             complement(58007..58342)
                     /locus_tag="VCX65_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEP5053068.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIISD
                     IEKLEVFREVGFDADEKYGSKIIHYHSTKGYTLSKDYIVLYHIEGEENRVVIDYLLPT
                     QSDYIKLFK"
     gene            complement(58332..58568)
                     /locus_tag="VCX65_000589"
     CDS             complement(58332..58568)
                     /locus_tag="VCX65_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053069.1"
                     /translation="MVSEAMTVLNKKNLTLSSALRLFLQNVVVTNEVDLLTEEELEKE
                     KLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
BASE COUNT        17286 a        11161 c        13204 g        17079 t
ORIGIN      
        1 tatttatctg aattatcatt tgtatgaaaa actaatttac cacttttgta gctagaacca
       61 gaagaatata attgatgttg tgatattaaa aattttctaa cctttagatc aatttcttga
      121 gctgtaactg ttgttttgtt agttgatatt tcgttgtaag gaacagagat ctgctttcta
      181 ttaatccata aattaacagg gatattttta ggtattgaag ttttttggta gggtgttatt
      241 ccgccgtacg tatatgctgt gacttttcct tttgataaat agttccaatc aaatgggacg
      301 gagaacacag ctattctatc tccagcttta aaatcattgg ctgcatattc gtccatttcg
      361 gagttaataa aaaaatctct agcatctcta acatcaagtt tcttagtcac taagttatga
      421 ctggttttaa aatcaattac tgtatctgaa tattcatata caatcgtact atagatattc
      481 cttagaaggg aattattatc tacttctaat ccaaacacag gacgagaaat tattgcaatg
      541 aatattgaag taaaagaaaa aataagtttt gtttttttca taaatagcct cttttcagga
      601 gttattattt tattatgttt taatataaca ctttcaaaag aaataatcat taacaatttt
      661 gtagatatac ttgctgacta tcaaatgaaa attgagacat gatactaaaa gtggattgac
      721 gcttttaatt aagccgatta gttatgaaac aagcaaaaaa gcctttaaac aaaggctttc
      781 agtctgaata gcccgggtta cccgtggcta ttttagtttt tcactctaat tagttgattg
      841 tattcatata gtgattgagc tgcttttgat ttgttaagac aatggtttta tgagggtatt
      901 tttggataac ggattggtat ttttttaatt ggtttcttga acgtccatct agtagaatcc
      961 atttcacaaa cgcaacgtca aatttttcct gacagttgtc agccatatca ggacgcgttt
     1021 ttcccctata gtttaaataa cgcttaaatg ctcgatagac acaatgaaac cgactgaaat
     1081 taacatagat aatgtgatta gcctcactca tgcgctcttc atagagacaa ttggcataat
     1141 tcccctcaat aatccaatct tgtttgagca ggcatgttga taaatcagct atcatgtcat
     1201 gatctgaccg ttcttgccag ttcgatgaga agtgtagttg gtctaaatgg accacctcac
     1261 aatggtaatg ttgacctaaa aatcgtgcta aggttgactt tccagagcca ctatgtccaa
     1321 tgatggcaat tttcaatgga tacctcctaa aaatgacgta tgaaatgact ataaagggta
     1381 tgaaatgtgt ttagattagt ttcttgatga gatgcgtgtc atcataaaat tgataaccat
     1441 gtttaggata aaaccgataa gactcaaacc attgttcttt aggttgacct aagtggatac
     1501 gaacatgact cttgccgatt ttccttagat aatcttctgc aaacgtcaga agttgactgc
     1561 caatgccttg atgttttaag cttggtttga tgaagagacg gtgcaagaag acctcatttg
     1621 ttttgggaat agaagaataa gcgattgagc caataacacg actttcttca ttgaccgcta
     1681 gccaaaaaca atcccctttt tccaaataac ttgtttcaat tgtcaaaaga tccgggttaa
     1741 tgctgggaat tctccttaag gcattttttg cttccaagac cataaaaatg aggtcatctc
     1801 tgtaatttcc tttgtactca attattttca taacagtctc caccttaatc ttaagcgctt
     1861 taattggtat cataccataa aaaaattact gcggggataa atgatggaac aaatcctctt
     1921 ctgacaagca aaaaaagcct ttaaacaaag gttttttcat gtatagttgt atacccccta
     1981 cagggctcga acctgtgacc catagattaa gagtctactg ctctaccaac tgagctaagg
     2041 aggcaagaat gctgtattgg caccggtgat ccacgttttt gtattgagcc cgcgcagtat
     2101 aagcaggtgg gtaacgcgct ctttcttgga agttgcgtcc gcgtgaaacg gcttgcagac
     2161 tagaaagggt ctttgtttcc cgaaaataca aagaaatagt cggtcaacac ttagatgtgg
     2221 attcgtatgc cacagcaatg tttctgtact tttataatac cactttttaa aattttttca
     2281 agcaaaatta tcgatttttg aaatcggttg cgatttttaa aactagcagt cagtctgaga
     2341 gcttatcaat acgctcttta tttgaaccaa gtgcgcgttc gtatttaccg gtttcattgg
     2401 cttcaaaata atgatgtcct actaatttat ctggtaggta ttgttgtttg acccattttt
     2461 cagggtaggc gtgtgggtag aggtaatctt tggcattgcc taggtcctta ctgccagcat
     2521 aatgcccgtc tctaagatgc cttggaatgg ggaggttacc tgatgttctc aaatcagcta
     2581 aagctgcatc catagctaaa taagctgaat tggatttagg tgatagagcc aaatcaatga
     2641 ccacgttagc gataagaata cgagcttctg gaaaaccaat gcgttgagcg gcatctagtg
     2701 cggtgacggt atgaacttgg gcgtcagggt tggctaagcc aatatcttcg taagcaataa
     2761 tggtcaatcg tcttgctaaa ctaggcaagt ctccagcttc tactaaacga gcggcgtagt
     2821 gcaggctagc attgacatca gaacctctaa tggatttttg taaggcagat aaaacatcat
     2881 aatgcccgtc cccgttttta tccatggtaa tataactacg ctgcagacta ttttccattg
     2941 tctctagact aatatgacgg ctactatctt cattaggaga agtagacatg actgctagat
     3001 ccaaggaatt ataagcagat cgtaggtctc catttgtggc ggtaacaatg aaatctagcg
     3061 cctcatcatc aattgtcact aaaaaaggaa atccccgttc tttgtcggaa attgctagct
     3121 gaatggctgt tttaatatcc tcgttagaaa gtggttccaa ttcaaaaatc tggaccctgc
     3181 ttctgatagc gggtgtcact gaaaagaagg ggttctcagt ggttgcgcca atcatgataa
     3241 tggtgccatt ctcaagtaaa ggtaaaagaa aatcttgttt tgtcttgtca aggcgatgaa
     3301 tctcgtctag taataatacc aagccaccag aaaatttagc ttcttccgca atttcttgga
     3361 gacgtttttt gctgtcaatg gtggcattaa aggtccgaaa ggcatatcta gtagtaccag
     3421 caatagcaga agcaatggaa gttttaccga ttcctggagg gccatagagg atcatggacg
     3481 atagtctatt tgcttccacc atgcgacgga tgattttgcc ttcgccaaca aggtgttttt
     3541 gtccgatgac ctctgaaatg gttttggggc gcattctgag cgctaaatga tcaggcatgt
     3601 aactgtcctt ctttcttttg ggggatgaga ttaacgggga atggctgcga tgaagttggc
     3661 gatcatggtc atgccatcag gagttccgat gctttctggg tgaaattgta gcccaaaaag
     3721 tggcagggtg tggtgttcaa aggccatgat ttcttgatcg tcacagtctc tagcagttac
     3781 gctaaaacct tttggtaact gatccacaac gatggaatgg taacgcatga cggtgatctc
     3841 ttgtggcagg gagcgaaaaa gactagcagg gccttgcgtt tcaatggtgc tttgtctccc
     3901 atgcatgaca cgtttagcca agcgtaagtt tccccctagg gtttcagcga tagcttggtg
     3961 tcccagacac actcctaaga taggttttgt ttggtaaaag tcttgaatga gttttggcat
     4021 ttggttggct tccttgggcc aaccaggacc aggtgagagg actagagcgt tagctttttt
     4081 ggccatgtca tataagtttg ggtcttggtt atacaagaca atcgtctcgt caaattcact
     4141 taaatattgg gcgaggttgt aggtaaatga atcgtaatta tcaattaaga gtatcatagg
     4201 ttccttaata acaaaagata agtggcagtt taggcttgac tcttagctaa gagggcatca
     4261 aggtgagtaa gcttaaggtt gagaggatag aggccacgga cagcatttcc tccaaaaata
     4321 gcgctagcct cttttaaatc agctagtgtc acctcttttt cctgagcttg accagtagct
     4381 agcagctctt ggcgaaaaag tcctggtaaa atacctacca caactggtgg tgtgtagagg
     4441 gtccgaccca gctgaacaaa gagattgcca atggacgttt ccaataattg ccccgcttgg
     4501 ttatagaata gctgttcata agatttttgc tcaatatgag gccggtagct ggtcttaaag
     4561 taggtaaaag gcgaagctgt cacgtccttc ttctgtaaag agagttgagc tgtcagaaaa
     4621 tcggctgaca aaggttccaa gggttgatca gagaggctaa tctttccatc cttggataaa
     4681 cgaatcatca agcggtaggc agcattatcc ttattttcca aataggttga cagttgtttc
     4741 tgcaaagctt tctcatcgta agggtaagca aaataagtgg ctgcttcttt aaggcgattg
     4801 aggtgttgct caaggaaggc tatttttttg tgtttcacct tggcggttgt tttgaggtca
     4861 aagatttgtt tgtgccgata gagaaaagct gttttttgat ggacttcctc gtattcgtct
     4921 tcccacttgc tttgccaagt gataccgcct ccgacaccat aagtagcttg attatgactg
     4981 agctggatgg ttctaatggg aacattgaag aaacggcgac catcaggtag gcaaatgcca
     5041 atacttccac aataaatccc ccttggtttt ggctccagag atgtgataat tgccatggtg
     5101 gagactttag gagcccccgt gatagagcca caaggaaaga gagctgtgag aatgtctatc
     5161 aggtcacagt ccgctttgac gtcaccaaca atggttgagg tcatttgcca gacggtagag
     5221 tatcgctcga cctcacagag cctatcgaca caaacactgc ctgtttggca aatttttccc
     5281 atgtcattgc ggagcaaatc cacaatcatc atgttttcag aacggttttt cccgtcagct
     5341 tggagccagt catgttcttg ttgatccagc cagctattaa ccccacgctt ggtggtgcct
     5401 ttcataggcc tagtagttaa cctgttgccc tcttgtttaa agaacaactc aggactagct
     5461 gaaataacag caaagtcatc atgggcgata taggcattgt agccagcagc ctgttcaacg
     5521 acgagtttat tgtaaatggc taagctgtca gctgcattga gttcctgagt taattgaagg
     5581 gtgtagttaa cctgataagt gttgccctgt tgcatctcac ggtgaatggt ttcaatggct
     5641 ttttgatagg cttctttttg agttgcgctg acccattggt tagggatagt aatgccgtca
     5701 taatcaagag gtaggtcttt tttttgacag gttttgtgca ctgtaaaata ggcaaggtac
     5761 tcgttgccta gtctgtcatt atgggtttgt aaggcattgt caaaaaaagc agctgcttca
     5821 taactgagat agcccaccac gtaatagccc agctgttggt agtgttgtac gttttcaatg
     5881 actggaccga cctgatctaa ggacttggct accaattcta ctaatggctc atcaaaaaga
     5941 tagcgttgcc cgagctcttt gaaatcaata atcgtttttc tatgcatacc caaattatat
     6001 cataaaagcg gttgctagag gtgatccagc cattaagacc ttctcttatg gtcaatatta
     6061 gtcaaatatg ttataattca gttaataaaa gttataacag tacgctcagc atgtcaaagt
     6121 aagtaaacta atgaggtctt acaaagctct atacagcaac agttagaaag attaggtata
     6181 aaaaaagatg gcaaaatacg gctttttatc agtattagaa gaagaaatgg ataagcattt
     6241 tcagtatgat tatgctatgg attgggacaa gaaaaatcat gcggttgaag tgacttttgt
     6301 gttagaagct caaaataaag aggccataaa aaccattgac gacagtggcg aagtgaccca
     6361 agatgatatt gtctttgagg actatgtgct cttttacaac cctgccaagt ctcaatttga
     6421 tgcagcagat tatttggtta ctattccttt tgacgctaaa aagggctttt ctcgtgaatt
     6481 cttagcttac tttgcgcaat ttctcaacga tgttgctatt gaagggcaca gcgatttgat
     6541 ggatttctta gcagatgaca gcaaggttga tttcggcttg gaatggaatg cgcaagcttt
     6601 tgaagaaggt caacaaggac tagaagaagc agcaagttac gcttacccaa ggtactaagg
     6661 tgacacacga gatggtgtaa caccattagg acaataacca aaaggtcaaa atagaaagga
     6721 catacttatg gaaacgtggc aagaagtgac ggttcatgtg catcgtgatg cgcaagaggc
     6781 tgtttcacat gtgttgattg agacaggcag ccaaggggtc gctatcgcgg atagcgcaga
     6841 ctatattggg caaaaggacc gctttgggga gttataccca gatgtggagc agtctgacat
     6901 gatagctatc atagcctatt acccaagtag cactaatttg gcggatgtta ttgcgaccat
     6961 taatgaacag ttagcggagt tagctagttt tgggttacag gttggtcagg ttactgtgga
     7021 tagtcaagaa ttagctgagg aagactgggc agacaattgg aaaaaatact atgaaccagc
     7081 tcgcatcacg catgatttaa ctattgtccc tagttggacg gattatgacg cttctgctgg
     7141 ggaaaaggtt attaaattag atcctggaat ggcatttggg acagggacac atcccacaac
     7201 taagatgagc ctttttgctc tagaacaaat ccttcgtggt ggtgagacag ttatcgatgt
     7261 agggaccgga tcaggtgtcc tctcgattgc cagttcctta ctaggtgcta aaaccatcta
     7321 cgcttatgac ttagatgatg tagctgttcg agtggctcaa gaaaacattg atttaaatca
     7381 aggaacagac aacattcatg tggctgctgg tgacctttta aaaggggtta gccaagaagc
     7441 ggatgtgatt gtagccaata tcttggcgga tatcttagtc ttattgactg atgatgctta
     7501 ccgtttgatc aaaaaggaag gttaccttat cttatcaggc atcatttctg agaaattgga
     7561 tatggttctg gaagctgcct ttagcgcagg attcttcctt gagacgcata tggttcaagg
     7621 tgagtggaac gcccttgtct ttaaaaaaac agatgatatc tcaggagtga ttggcggcta
     7681 atgcaacagt attttattaa aggcaaagca gaaaaagagg taacaattac cgataaagat
     7741 accatcaagc acatgtttca agtgatgcgc ttggctgaca aggctgaagt tgtcttggtc
     7801 tttgatgatg gggtgaagta tttagccaag gtgaccaata gtatggctca tgagttagag
     7861 attatagagg ctttgccaga tcaggtggaa ttgcctgtta aggtgactat tgcttctgga
     7921 tttcctaaag gcgataagtt agacacgatt gcacagaaag tgactgaatt gggagccagt
     7981 gcgctatggg gctacccagc agactggtca gtggtcaaat gggatggcaa aaaattagct
     8041 aaaaaagaag acaaattggc taagattgta ttaggagcgg ctgagcagag caaacgaaat
     8101 agggtgcctg aagttcacct ttttgagcac aaagcagagt ttctaaaaag cctttctggc
     8161 tttgatcata ttttcgttgc atacgaagaa acagctaagg caggtcagct agcgaccttg
     8221 gcgcgtgaag taaaagaagt taagccaggg gcaaaaatcc tctttatctt tggaccagaa
     8281 gggggaattt ccccaactga aatcactcag tttgaggcag caggtgccat caaggtgggc
     8341 ttaggccctc gcattatgcg agcagagaca gcgccgctat atgccttaag tgctcttagt
     8401 tatgctttgg aattgcaggc atcaaaataa gtaagctgct gcttacttta gaaagaagag
     8461 gctaaagaaa cgaacaggca gttcacgatt gtgtcaacgg ccttttttta ttgcttcttg
     8521 ttttttcgaa gagcgttgat ggtctcatca ccaaaaaagg aaatgggctc ttgttatctt
     8581 tttggtaagt tacactacca tttaatgaag aaaaacgact aacatctgtc taagaaaacg
     8641 ctttacaaat tgttgcgagg ctagtataat aaaggtatca gatcaatgaa aacgattgca
     8701 tcactgagtt gcagtctata tcattgtgtc acaaaagcgc cttaagggca gctatggcta
     8761 aaaggggata ataaaggaga gatagaatga aaacatcatt caagcaactg tttcgtttcg
     8821 aattttggca aaaatttggg aaatgtctta tggtcgttat tgctgtcatg ccagcggctg
     8881 gtttaatgat cagtatcgga aactctattc caatgattaa ccacgaatca gcatttttgg
     8941 catctctagg caacattatc gctcaaattg gttgggctgt tattgttaac cttcatttgc
     9001 tatttgcctt ggccattggt ggtagttggg ctaaagaaag agctggaggg gcccttgcct
     9061 cagggcttgc ttttgtcttg atcaatcgga taacaggtgc tttttatggc gtgtctagtg
     9121 ctatgctagc tgatccagaa gcaaaaatca caagcctcct tggcactcaa atgatcgtta
     9181 aagattattt caccagtgtc ttggagtctc cagctttaaa cacaggggtt tttgttggga
     9241 ttattgcagg gttcgtagga gcaacggcct ataacaaata ctataattac cgtaaacttc
     9301 ctgaagtttt gaccttcttt aatgggaagc gttttgtacc gtttgtcgtt attttacgtt
     9361 ctatttttgt agcccttatt ttggttgttg tttggccggt gatccagtct gggattaaca
     9421 gttttgggat gtggattgcc tcttcacaag attcagctcc aatcctagcc ccattcctat
     9481 atggtacctt ggaacgtctc ttgttgccat ttggtcttca ccacatgttg acgattccaa
     9541 tgaactatac agctcttggt ggaacttatg aggtcatgac aggtgcagca gcggggacaa
     9601 aagtatttgg tcaagaccct ttgtggcttg cttgggtaac tgaccttgtt caccttaaag
     9661 gatcagacgc ttcagcctat agtcacttaa tggatagtgt gactccagct cgctttaagg
     9721 taggacaaat gattggagct accggaacat tgatgggggt tgccttagcc atgtaccgta
     9781 atgtggatgc cgataaaaaa catacataca aaatgatgtt catctcagca gcggcagcgg
     9841 tctttttgac aggggtaact gagccacttg agtacctatt tatgtttgca gcaatgccac
     9901 tttacatcgt ctatgccctt gttcaaggag cttcatttgc catggcagac cttgtgaatc
     9961 tccgtgttca ctcatttggg aacattgagc tactaacccg tacccctatg gcccttaaag
    10021 caggtctagg catggatgtg attaactttg tttgggtttc tatcctcttt gcagttatca
    10081 tgtactttat tgcggatatg atgatcaaga aaatgcatct cgcgacagct ggccgtttag
    10141 gcaactacga tgccgatata ctgggtgacc ataacactca agcaacacct acccaagtag
    10201 cagatagcaa ctctcaagtc gtacaaatca ttaatctcct tggtggggca ggcaatattg
    10261 atgatgttga tgcttgtatg acgcgcttac gagtgacggt caaagacccc gctaagattg
    10321 gcgctgagga cgattggaaa aaagctggcg ctatgggctt gatccaaaaa ggcaacggcg
    10381 ttcaagcggt ctatgggcct aaagcagata ttttgaaatc agatattcaa gatttgctgg
    10441 actcaggggc tgttattcca gaagtcaaca tgtcacagct cactagcaaa ccgactcccg
    10501 caaaagattt taaacacgtg acagaagaag tgctatcagt ggcagacggg atggttctcc
    10561 caatcacagg tgtgaaagac caggtgtttg cggctaagat gatgggagat gggtttgcgg
    10621 ttgaaccaac ccatggtaat atctatgcac cagtagctgg ccttgtgacc agtgtctttc
    10681 cgaccaagca tgcctttggt ttactgacag ataatggtct tgaagtgctg gtgcacgtgg
    10741 gacttgatac cgtcgcctta aatggtgtgc ctttttcagt caaagtctca gaaggacaac
    10801 gggttcatgc aggtgaccta ttagtcgtag cagatcttgc tgctattaaa tcagcagagc
    10861 gtgaaacaac cattgttgtt gcttttacca acacaacaga gatccaagat gtgaccttga
    10921 catctttagg agctcagcct gctaagacta aagtagctac cgtagaactt taacaaaaca
    10981 tcacgagata gtgataggta atagccatag ctggtttagg ccctatggct cttcttgtct
    11041 tataaaggag gattaatgac caaggtatta acactgaata ctcattcgtg gatgcaagcc
    11101 aacactctta aaaaattagt tgctttggct gagcatattt tagctgaaaa atacgatatc
    11161 atttgcttgc aagaaatcaa tcagttaatc gagagcgagc tggccacaga tttaccaaga
    11221 tatcaagctc tttcagggac accaaacatt cataaagacc attttgccct gctcttgatc
    11281 cattatttac aaaaacgagg gcagcactat tattggtctt gggcttataa ccatattggc
    11341 tatgacattt accaggaagg cgtggcaatc ttatcaaaac aacctattca tgtttcagat
    11401 attctcgtgt cagcgatggc tgatgaaaca gactaccaca ccagacgctc actcatagcc
    11461 aaaaccacgt tagatggcaa agaagtcgct gttgtcaatg tgcacctatc ttggtttgac
    11521 aaagggtttt taggggagtg ggagaaatta gaaaaagaac tgctcacact aaactgtccc
    11581 ttgctactta tgggagattt taacaatcca acggatcaag acggttatca agtgatgatg
    11641 ggtagccccc tagacctaca agatagccat aaggttgctg accatgtgtt tggtgatcat
    11701 agcatcgtgg ctgatattga tggctggcaa ggtaacaaag aagccctcaa ggtggaccat
    11761 gtctttacca gcaaggactt catcatccga tcttctaaga ttacctttga aggcggagat
    11821 gcgccagtcg tcagtgacca ctacggttta gaagtgacat taggctggcg ttagagcatg
    11881 tgctaacagg cacaccacat aggagaagcc aagacacata agaaactgcg atcgtctagg
    11941 gggattagga gaacacaaag aggtctaacg agctcaaggt agagctggtt agacctcttt
    12001 agtcatgtca gtaaccctaa aaaaccaggg cttttttgcc accaaccatc tgagcttcac
    12061 agaaagtacc gccaagcgtt cagttgcctt gctaaagtct gcataggggt atttctagga
    12121 gcgcttggag tgatcccaag ccccaagaag cactgtgatc gctcttttca aaggctgaga
    12181 aatcgcaagg cgtagggtaa gagacctccc tagttggtgt cctaaaagtg ctctttttta
    12241 aaacagctat gatcatctat agacggtcta gctgttaggc agtgtctgtg tgtcgttaga
    12301 cgagtgtctg gagctggcct ccatgatgac ctgggctaac cgcgaaatgt catcaggagt
    12361 ccctcgcagc tcaaaatcac ctagcagtgg aaagccaaag cgtttggcat actgtttggc
    12421 tgtcaggcaa tactgatggt taaagttttt gttgcctgaa ccaataatcc caagacaacg
    12481 ctgggcgttg ccatgggcgg caataaactc tcctaaagga gtggtgagga tctccacctc
    12541 accagagtca acgccatttc cgccttctag ataagtgggt agaatcgcca caaactcttc
    12601 cttgacggga aaagtctcgt gcttcaaatc tttaatgtta atctgtttga catggtaatc
    12661 gtaattgtct gctaaataaa gggatagccg cttgacaaag ctaagggtgt tgccactgag
    12721 gctaataaaa acaagagtaa tctgaggcat aagtgtctcc tttttttatc ctacaaggtt
    12781 tcttcataag cttaccacaa tcaagaccaa caaacaagta aagaagaaac ctagcgatat
    12841 ccaaccagac aagaaggtac aagcggtcaa aaaaagtaac atttcaaaaa agagtgacct
    12901 taaagaaagg atccggatgc cctcgactta aaaacgaggc aggcaagtgc caaagtagcc
    12961 ctctgatctc cacaaaagag tgatcagtca aaatctaaaa gatgaacaac aaaagagaac
    13021 tttacaatcg ttttcacact ctattataat actattataa ataatcaggt ctagctacca
    13081 tgttattttt atctaaaaca caccatctaa taaagaaaga gagaacaaca tatgttgaca
    13141 tcaaaacacc acaatctcaa caaactagtc tggcgctacg ggctaacctc agccgctgcc
    13201 gtccttctag cctttggagg cggggcaagc agcgttaagg ctgaggtttc tactgcggct
    13261 atgacgaagg aggagagaca acaagaaatt gagaaaatta aagaagacat taagaaagaa
    13321 tatccaaaag cgtctgagga aaaattttgg gagagtagct tttggggaag aaggtacttt
    13381 aatgaacaag agtatctaaa atctttacaa agttttactg agcaaagact ccaagatatt
    13441 gtaaatctga ttgaaaaagg tgcaacaaaa ggtgacaaag gcgatgctgg tcctaaaggc
    13501 gagcgcggcc cagcaggccc acaaggtccg gtaggaccta aaggtgaagc aggtaaggtt
    13561 ggtgcccaag gtcctaaagg tgatcctggt gccccaggta aagacggcgc caaaggtgaa
    13621 aaaggcgaca aaggtgatac cggtgagcgc ggtgaaaaag gtgacatcgg agcaactggc
    13681 gcacaaggcc cacaaggtga aaaaggtgaa actggcgcac aaggcccagc aggcccacaa
    13741 ggtgaagcag gcaaaccagg tgagcaaggt ccagcaggcc cacaaggtga agcaggcaaa
    13801 ccaggtgaaa aagctccaga aaagagccca gaaggcgaag caggccaacc aggcgaaaaa
    13861 gctccagaaa agagcccaga agtgacacca acgccagaaa caccagagca accaggtgaa
    13921 aaagctccag aaaagagcaa agaggtaact ccagctccag aaaaacctgc tgacaaagaa
    13981 gctaaccaaa cgccagaacg ccgcaatggc aatatggcta agacacctgt agccaacaac
    14041 cacagacgtc taccagcaac tggtgagcaa gccaacccat tctttacagc agcagcagta
    14101 gcagtgatga caacagctgg tgtcctagcc gttacaaaac gcaaagaaaa caactaatcc
    14161 tctgaattga gagaccttac tgataagcaa acataataga gagagcccct tggttctctc
    14221 tatttttggt cgggagctgg ccgttggtat catgctcacg cctgagagat cccaaaagat
    14281 atcaaaagca gctcactaac cgttttctaa gaaaaggtca cactaagcgc tttcttagca
    14341 gattctgcct tttgcttttg tgtgtaaagt gttaaaatag ggaaaagaaa tgctagatga
    14401 ggaacgaaat ggcaaaaata atgaacgtaa caggagaaga agtcattgcc ttagcggcca
    14461 cctatatgac caagactgat gtggcttttg tggcaaaggc tttagcatat gcaacagcgg
    14521 cccatttcta ccaagtgaga aagtcaggcg aaccctatat cgtccatccg attcaggtgg
    14581 cggggattct ggctgatttg catctggatg ctgtgacagt tgcctgtggc tttttacatg
    14641 atgtcgtaga agatacggat attaccttag atgagatcga agcagacttt ggccaagatg
    14701 ctcgtgatat cgttgatggt gtcaccaagt taggtaaagt tgagtacaaa tctcatgagg
    14761 agcaactcgc cgaaaaccat cgcaaaatgc tgatggctat gtctaaagat attcgcgtga
    14821 ttttggtgaa attggctgac cgcctgcata atatgcgcac cctcaaacat ttgcgcaagg
    14881 acaaacaaga gcgcatttcg cgcgaaacca tggaaatcta tgcccccttg gcgcatcgtt
    14941 tggggattag tcgcatcaaa tgggaactag aagatttggc ttttcgttac ctcaatgaaa
    15001 ccgaatttta caaaatttcc catatgatga aagaaaaacg tcgcgagcgt gaagctttgg
    15061 tagaggctat tgtcagtaag gtcaaaacct atacgacaca acaagggttg tttggagatg
    15121 tgtatggccg accaaaacac atttattcga tttatcggaa aatgcgggac aaaaagaaac
    15181 gtttcgatca gatttttgat ttgattgcta tccgttgtgt catggaaacg cagagcgatg
    15241 tttatgctat ggttggctat attcatgagc tttggcgtcc catgccaggc cgcttcaagg
    15301 attatattgc agctcctaaa gctaatggct accagtcgat tcataccact gtgtatggac
    15361 caaaaggacc tattgagatt caaatcagaa ctaaggacat gcatcaagtg gctgagtacg
    15421 gggttgctgc tcactgggct tataaaaaag gcgtgcgtgg taaggtcaat caggctgagc
    15481 aagccgttgg catgaactgg atcaaagagc tggtagaatt gcaagatgcc tcaaatggcg
    15541 atgcagtgga ctttgtggat tcggtcaaag aagacatttt ttctgaacgg atttatgtct
    15601 ttacaccgac aggggccgtt caggagttgc caaaagaatc aggtcctatt gattttgctt
    15661 atgcgatcca tacgcaaatc ggtgaaaaag caacaggtgc caaagtcaat ggacgtatgg
    15721 ttcctctcac tgccaagtta aaaacaggag atgtggttga aatcatcacc aatgccaatt
    15781 cctttggccc tagtcgagac tgggtaaaac tggtcaaaac caataaggct cgcaacaaaa
    15841 ttcgtcagtt ctttaaaaat caagacaagg aattgtcagt gaataaaggc cgtgatttgt
    15901 tggtgtctta ttttcaagag cagggctatg ttgccaataa ataccttgac aaaaaacgca
    15961 ttgaagcgat ccttccaaaa gtcagtgtga agagcgaaga atcactctat gcagccgttg
    16021 ggtttggtga cattagtcct atcagtgtct ttaacaagtt aaccgaaaaa gagcgccgtg
    16081 aagaagaaag ggccaaggct aaagcagaag ctgaagaatt ggttaagggc ggtgaggtca
    16141 aacacgaaaa caaagatgtg ctcaaggttc gcagtgaaaa tggggtcatt atccaaggag
    16201 catcaggcct cttgatgcgg attgccaagt gttgtaatcc tgtacctggt gatcctattg
    16261 acggctatat taccaaaggg cgtggcattg cgattcacag atcggactgt cataacatta
    16321 agagtcaaga tggctaccaa gaacgcttga ttgaggtcga gtgggatttg gacaattcga
    16381 gtaaagatta tcaggctgaa attgatatct atgggctcaa tcgtagtggc ctgctcaatg
    16441 atgtgctcca aattttatca aactcaacca agagcatatc gacagtcaat gctcagccga
    16501 ccaaggacat gaagtttgct aatattcacg tgagctttgg cattccaaat ctgatgcatc
    16561 tgaccactgt tgtcgaaaaa atcaaggcag ttccagatgt ttatagcgtg aagcggacca
    16621 atggctaaga aaggataaaa ccatgaaact tgtcttgcaa cgggtcaaag aggcctctgt
    16681 ttctattgat gggaaaattg ctggcgctat taaccaaggg ttgttgttgt tagtaggtgt
    16741 gggaccagat gataatgcag aagatttggc ttacgctgtg cgaaaaatag tcaacatgcg
    16801 cattttttca gatgctgatg gcaagatgaa tcagtctatc caagacatca agggcagtat
    16861 cttatctgtg tcgcaattta ccctttatgc tgacaccaaa aagggaaacc gtcctgcctt
    16921 tactggtgct gctaagccag atttggctag ccagttgtat gatagcttta atgaacaatt
    16981 ggcagagttt gtgccagttg agcgtggcgt ttttggggca gatatgcagg ttagtctcat
    17041 caatgatgga ccagttacga ttattttaga cacgaaatgt cactagtctc tacaactaag
    17101 aggttagaaa aaagcaagca actgttgata gcgtgttgct tgcttttttt gtcagttaat
    17161 ctcatcgttt tagaagatcg tggttatttg tcgttagggt tatcaggtat aggtgtccct
    17221 gtataacgca ggtagctgta aacttctcgt tcttcttcgg tataacgatc tttatcataa
    17281 gctaaatgat agctagcatt ctctccttcg ggtcgcttgc ccatataaac ggttatgata
    17341 cggttggtgt cattgtgatt atcctctact tttccagtta aggtatagtc cataatacca
    17401 aaagcatcga gattgttgta gagtagttta gccttatcac gaggatcgta taaatctctg
    17461 aagtctaagt tatgttcgct agctgttaag agctgctcgc tttttagcaa tttgttggtg
    17521 ttgacatcaa cgtaattgat ggtgaacagt ttcaagtgac tgcgatcaaa gggatcatac
    17581 ggcttttccc cttttttaag gatgtaatat ttctcagaga taaggtcagt gttgttcatt
    17641 ttttcttcct gaccagattt tttattgatc ccataagctt gttcccggtc tttgatatgg
    17701 taagtaaact cttgatccat tggtaaaatc gtacggaaaa tgtcattgtc atgagtgacg
    17761 attgaggagt cacgttttgt aatgatataa tctggatgtt tttttgatag gataaattgg
    17821 gcaattgctg ctaactcttg tgatgaaaga gagtcaccaa ctgccagtgt ggtcaaatgg
    17881 tattgctctt ttaacgatgg cgtaaagtct aaatttcctg tttcggagac aaagctcact
    17941 tcatagttga cgttaacgcg ttcagctgag ttgtgaacgg ctttaggttg atacggtcta
    18001 acgcgcacat gcccgcttag caaaaattct tggacaggtt gggtcggcaa ggttaccgaa
    18061 tcatctcggt cagcaaagta gaccttgccg tttcgatcag taatggttgc atcgcttgca
    18121 aaatcaatga cctcaaagta gccgtcgtta ctgtgaacgt tagcgatcaa ttgttcttga
    18181 atagccttta ataagtcagc tttttcaagt ttatgtggca ttgcgctact atttgtagca
    18241 aatggttttg attttggact taagccttgc tctgtctttc ctccatgagc aggttgtgat
    18301 gttaggtcaa tttcaaaaaa tttaaggcta atttcttgat tcgtcccctc aacagtacca
    18361 gcaacgctaa caactaattg gctgttgttg acagatggac ggtctagcag ccattcaggt
    18421 ccagcaatag cttggacagg cttgactgtt ccaaatgtta atgcaaacag cagtgcaaac
    18481 atcccaaaag ataagtaatt tttcatagaa acctcctaaa agttaagttt caatccccat
    18541 tattagaata acataataat tttatagata caaacaaaaa cctaataatt gtttttaaat
    18601 gatatcttaa tgataacgtc atgataatga aaaaagagaa ataatacctg ttttagtata
    18661 aacataaatt aatcttccga taaatagcta tttgattgaa tgttcttgct aaaaatgaat
    18721 aacacttatt tagctttaat gattaaaaag acagaaaata caaaatcgtg ctgacaacaa
    18781 accgaactgt gtgataaaga gtcatgtgtt ataatggttt aaagaccatc atgaaaggaa
    18841 tggctatgga gctaaaagac tattttccag agatgcaagt aggccctcat ccgttaggag
    18901 ataaagagtg ggtgagtgtc aaagaagggg accaatatgt gcattttccc aaatcatgtt
    18961 tatccgaaaa agagcgctta ttacttgagg tggggctggg tcagtgtgag gtcttgcagc
    19021 cgctagggtc accttggcag cggtatttgc ttgatcatca gggcaatccc cctcagctgt
    19081 ttgagacttc tcagttcatt tacctcaatc atcagcaggc tttaccagat gacttagttg
    19141 agttgctcca acagatgatt gcagggcttg aggtcatttt gcctatcagt gcaactcaga
    19201 cggcattttt atgccgacaa gcaatctcaa taaaggtctt gcgctggctt gaagatctcc
    19261 tgccaacgct agaaagtgat tttggtttgg ccttaaccat gtttgttgga aatgcctggt
    19321 atcaagtagc tgcgggtaca ttgagagagt gttttgagga ggaatgtcag ctgttaacgg
    19381 cctatttaag gcaacaatca ggcagaaaat tattaacatt ttcaggactg atgctgtggt
    19441 ctttgctgtc gcaccacact tttttggcat tgacgcgtca gtttcaccaa tccctaagtc
    19501 ctcaaagtga tatggccgat gtggttcacg cgctatggtc agaacacggc aatctggtgc
    19561 agacagcgca gcgcttgtat attcaccgta actccttgca atacaaactt gataaatttg
    19621 ctcagcaatc aggactccac ttgaagcaat tggatgattt agcctttgct catctctttt
    19681 tgttgaaata ttaggaaagc cacagagctt tcttttttgc tgcctggact gtagctgata
    19741 aggagaatga tagatcgttc agcttgtttt ggctcctgtg accggcctgt gtttacatag
    19801 ttttcttggt ttatggtccc ttacgacttg actagccctg ctattgtgca agttgcccaa
    19861 agaagtttgg tcgctttgtc tctgttttga aagcgctatt tttgttataa taaaagcatc
    19921 atataaaaga tatcagcggt ttctagcttt gcagtcagct agaacatttg ctggctaaat
    19981 aggagttata catggttgaa ttaaatctaa atcacatcta taaaaaatac ccaaatacta
    20041 ctcattatgc cgttgaagat tttgacttgg acattaaaga caaagaattt atcgtctttg
    20101 ttggaccttc aggatgtggt aaatcaacca ctcttcgtat gattgcaggt cttgaggaca
    20161 tttctgaagg agagttaaaa atcggtggcg aagtggtgaa tgacaagtct cctaaagacc
    20221 gtgatattgc catggtcttt caaaactacg ccctttaccc acacatgacc gtgtatgata
    20281 acatggcctt tggtttgaaa ttacgtaagt acaaaaaaga tgatattgac cgtcgtgtca
    20341 aggaagctgc gcagattctt ggtttgaccg aatttttaga gcgtaaacct gctgacctgt
    20401 ctggtggtca acgtcagcgt gtggctatgg gacgtgctat tgtccgtgat gctaaagtgt
    20461 tcttgatgga cgagcctttg tcaaacttgg atgcgaagct tcgtgtctcc atgcgtgctg
    20521 aaattgctaa aattcaccgt cgtatcggct caacaactat ttacgttacc catgaccaga
    20581 cagaagccat gactttggca gatcgtatcg ttatcatgag tgccactaaa aaccctcaag
    20641 gtaatggaac gattggtaaa attgagcaag tgggttcacc acaagaattg tataaccttc
    20701 cagctaataa attcgttgcc ggttttatcg gaagccctgc catgaacttc tttgaagtgg
    20761 aagttaaaga tggccgcatt gtgagtgaag atggtcttgc tattgcgatt cctgaaggtc
    20821 aagcaaaaat gcttgaagcg gctggttaca aggggaaaaa agtcactttt ggtattcgtc
    20881 cagaagacat ttctagtaga caaatcgtgc atgatactta tccaagtgca actgtcacag
    20941 cagaagtttt ggtttctgag ttactgggct ctgagacgat gctctatgtc aagcttggac
    21001 aaactgagtt tgcttctcgt gtagatgcgc gtgatttcca tagtccaggg gagcaagtta
    21061 gcttgacctt taatgtggct aaagggcatt tctttgacag agataccgaa caagctattc
    21121 gttaaggtgt aagcgatatt cataaaaagg ttgggttcca acctttttat catgtcattt
    21181 gcgcaaacga ttgcacaaaa agagaaaaaa cgttaaaata aaagatgaat gaatgattaa
    21241 taggagaaga ataatgaaga aacactggtg gcataaagct acgatttatc agatttaccc
    21301 gagatccttt aaagacacca gcggcaatgg tattggtgat ttaaaaggca ttaccagtca
    21361 actggactac ttgcaaaaac ttggcattac agccatttgg ttatctcctg tttaccaaag
    21421 tccaatggat gacaatggtt atgacatctc tgactatgaa gcgattgctg atgtttttgg
    21481 agacatggca gatatggatg agctcttagc agcagctaat gagcgaggca ttaagattat
    21541 catggacttg gtggtcaacc atacgtctga tgagcatgct tggtttgttg aagctaggga
    21601 aaaccctaat agtcctgagc gtgattttta tatttggcga gatgaaccta acgatttgac
    21661 ttctattttt agtggctcag cttgggaata tgataatgca tcaggccaat attatttgca
    21721 cctttttagc aaacgtcagc cagatctcaa ctgggagaat gaagctttac gtcataaaat
    21781 ttacgatatg atgaatttct ggattgctaa aggcatcggt ggttttcgta tggacgtgat
    21841 tgacctgatt gggaaggttc cagattctga aatcacgggt aacgggccgc gcttacacga
    21901 ttacctcaaa gaaatgaatc aagcaacctt tggcaatcat gacgtgatga ctgtcggtga
    21961 gacttgggga gcaacgcctg aaattgctcg ccagtattct cgccctgaaa acaaagagtt
    22021 atccatggtc ttccaatttg agcatgtggg tcttcaacat aaacctgacg ctcccaagtg
    22081 ggattatgcg gaagaactgg atgttcctgc tcttaaaact attttcagca agtggcagac
    22141 agaattaaag ttgggagaag gctggaattc gcttttttgg aataaccatg acttgccacg
    22201 ggtcttatcc atttggggca atgacagcac ttaccgagaa aaatcagcca aggctttagc
    22261 tattttactg catttgatgc gaggaacccc ttacatttac caaggagaag agattggcat
    22321 gaccaattat ccttttaaag acttaaccga ggttaatgat attgagtccc ttaactatgc
    22381 taaggaagct atgggaaatg gagtgtcagc tgcgcgtgtg atggatagca tccgtaaggt
    22441 aggacgagac aatgctagaa cgccgatgca gtggtctaag gacacacatg ctggcttttc
    22501 tgaagcaaaa gagacttggt tgccggtcaa ccccaactac caagacatca atgtggccga
    22561 tgcccttgct gatccagact ctatttttta cacctaccaa aaattgattg ccttgcgtaa
    22621 ggagcaggac tggctagttg aagcggatta tcacctcttg ccaacagctg ataaagtgtt
    22681 tgcttatcag cgtcagcttg gagaagagac gtatgtgatt gttgtcaatg tgtctgatga
    22741 ggagcaagtc tttgccaaag acttaacagg tgcacaagtg atcatcacca atacagatgt
    22801 ggacacggtg ttcgagacca agcacttaca accttgggat gccttttgtc tcaaactgaa
    22861 ggcctagcag ttgtatgtga tttgagttta cccaacagcc aagcgagtgg aaactcgttt
    22921 tggctgtttg atttttgaga tcctattaag gggtgatagt cattgtttga gctgtgttct
    22981 aagttgaagt gcggcatgtc ttgcaagcgc ttgcgcaatg tgataagata gtcttgtttg
    23041 aatgttatac taaatggagg tcttatgaaa aagaaagtca accaaggatc aaagcgctat
    23101 caatatctgt taaaaaagtg ggggataggt tttgtaatcg ctgcaactgg gactgtcgtg
    23161 ttagggtgca cccctagtat cttaacacat caagttgctg ctaaaaccat tgttggacta
    23221 gcccgcgatg aagctcaaca aggagatggc aatgctaaat ctggtgatgg tcttcaatcg
    23281 tctagcaagg aggcaaaacc agttttagac agctcgttag ctaatcctgc tagtattgct
    23341 gagcatcatt tgcgtatgca ttttaaaaca ttgccagctg gtgagtcgct aggaagcttg
    23401 ggactttggg tgtggggaga tgtggatcaa ccttcaaagg attggccaaa tggtgctatc
    23461 accatgacaa aagcgaaaaa agatgactat ggctattatc tagatgtgcc actagcagct
    23521 aaacaccgcc agcaagtgtc ttatctcatt aataataaag ctggagagaa tctttcaaag
    23581 gaccagcaca tctcgcttct cacaccaaaa atgaatgaag tttggataga cgagaattac
    23641 catgcgcacg cttatcgacc tttgaaaaaa ggttaccttc gaatcaacta ccacaatcaa
    23701 tcgggacact acgataactt agctgtctgg acctttaaag atgtcaaaac cccaacgacc
    23761 gactggccaa atggacttga cttgtcacat aaagggcctt atggagctta tgttgatgtc
    23821 cccttaaaag aaggagctaa cgaaatcgga tttttaatcc ttgataaaag taagacagga
    23881 gatgctatta aagtgcaacc aaaagattat ctgtttaaag agttagacaa tcatactcag
    23941 atttttgtca aagacactga cccaaaagtc tacaacaatc cttattatat tgatcaggtt
    24001 agtctcaaag gagctgaaca aaccacgcca aatgagatta aagccatttt tacgacctta
    24061 gatgggcttg atgaagatgc ggtgaaacaa aacatcaaga tcactgacaa agcagggaaa
    24121 actgttgcaa ttgatgagtt gacacttgac agggataagt ctgtaatgac attaaagggt
    24181 gattttaagg cgcaaggtgc agtctacacg gttacatttg gagaagttag ccaagtcgct
    24241 cgccaatcct ggcaattaaa agataaactc tatgcttacg atggtgaact tggagctacc
    24301 ctagctaagg atggttctgt tgatttagcg ctatggtctc caagtgctga tactgttaag
    24361 gttgtcgttt atgataaaca agatcagaca agggtggttg gtcaagctga tttgaccaag
    24421 tcggacaagg gtgtttggag agctcatctg acttctgata gtatcaaggg cattagtgat
    24481 tacacaggct actattacct ttatgaaatc acgcgcggtc aggaaaaagt catggttttg
    24541 gatccttacg ccaaatctct cgctgcctgg aatgatgcga ctgctactga tgacatcaaa
    24601 acagcaaaag ctgcctttat tgatccaagc aaactaggac caacaggcct tgattttgcc
    24661 aaaattaaca actttaaaaa gcgtgaagac gctattatct atgaagcaca tgtgcgagat
    24721 tttacgtcag ataaggctct agaaggcaag ttaacacacc cttttgggac tttttcagct
    24781 ttcgttgaac agctagacta tctcaaagac ttgggggtta cccacgttca attgctaccg
    24841 gttttgagtt atttttatgc caatgagctg gacaagagcc gctcaacagc ctacacgtct
    24901 tcagacaata attacaactg gggttatgac ccacaacact actttgccct ttctggcatg
    24961 tattcggtaa atcctaacga ccctgcttta cgtatcgcag agcttaaaaa ccttgtcaat
    25021 gagattcaca aacgtggtat gggtgttatt tttgatgtgg tttataacca cacggctaga
    25081 acctatctct ttgaagattt ggaacccaac tactatcatt ttatgaatgc tgatggcaca
    25141 gctagagaga gttttggcgg aggtcgtcta ggaacgacac atgccatgag tcgtcgtatc
    25201 ttggtggatt cgattgctta tctgactcgt gaattcaagg tagatggttt tcgtttcgac
    25261 atgatgggtg accatgatgc ggcagctatt gagcaagcct ttaaggcagc caaagccatt
    25321 aatccaaata ccattatgat tggcgaaggc tggcgtacct accaaggtga tgaggggaaa
    25381 aaagaaattg cggcagatca agattggatg aaagcaacca atacggtcgg tgttttctct
    25441 gatgatatca gaaataccct caagtcaggt ttcccaaatg aaggcacagc agcctttatt
    25501 actggtggcg caaaaaatct agaaggactg ttcaaaacga tcaaagcaca gcctagtaac
    25561 tttgaagcag atgccccagg agatgtagtg cagtatattg cagcccatga caacctgacc
    25621 ttacatgatg tcattgccaa atccatcaat aaggatccta aagtggctga agaagagatt
    25681 cataagcgta ttcgtctagg aaataccatg attttaactg ctcaagggac tgcctttatc
    25741 cattctggtc aggaatatgg acgaaccaag cagcttctaa atcccgacta caggacaaag
    25801 gtgtctgatg acaaggtgcc aaataaggcg actctgattg atgctgtagc gaaataccct
    25861 tacttcatcc acgattctta tgattcgtct gatgcggtca atcattttga ctgggcaaag
    25921 gcaacagatt ccatagctca cccgattagc aaccaaacaa aagcctatac acagggccta
    25981 attgcgttgc gtcgctcaac agatgccttt acaaaagcaa ccaaagctga ggtagatcgg
    26041 gatgtgacct tgatcaccca agcaggacaa gatggtattc aacaagagga ccttatcatg
    26101 ggttaccaaa cggtggcatc aaatggagat cgctatgctg tctttgtcaa tgcagacaac
    26161 aagacccgca aggtagtttt acctcaagcc taccgctatt tgctaggagc ccaagtgctt
    26221 gctgatgctg agcaggctgg tgttactgcc attgctaagc ctaagggagt ccagtttacc
    26281 aaagaaggct tgactattga tggcctaact gccctggtcc tcaaagtatc ctcaaaaaca
    26341 gctaatccct ctcagcaaaa gagtcagaca gacaatcatc aaaccaaaac accagatggc
    26401 tcaaaagacc tagataaatc attaatgact aggccaaaaa gagctaaaac aaaccaaaag
    26461 ctcccaaaaa cgggtgaagc ctcctcaaaa ggcttattag cagctggagt agctctgctt
    26521 ttattggcta ttagcctgtt gatgaagcgc caaaaagatt agggtggtgt taatagagac
    26581 aaaaagattg ctgtttgcgg attctttttg acggctataa aagctctgag ctgtgaaaag
    26641 accttgtgat tgagaaaatt gctactttag tgtatcatga gaccaaaaga gaaggagaca
    26701 tccatgacat ttgaagaaat cgttgcgaat tttataccgt cgagtgttgc agaagtcaca
    26761 tcagctattg ctagtggcaa agacatgatt gtctttttag gacgttcgag ctgtccttat
    26821 tgtcgccgct ttgctcctaa gttggcacaa gtggcaacag ataatcaaaa agaagtctat
    26881 tttgtggata gtgaaaacgc tgctgatgct gctgagcttg ctgcctttcg tgagaactac
    26941 caattagtga cagttccggc tttgctggtt agttacgatc agcaccaaag ggctgtatgt
    27001 gattcaagtt tgacaccaga tgacatctta gcttttttga ctcgtgagta aaggactgcg
    27061 cttagcgtct cgtttaaaga agaaatcagg taacgtctag tcttgctata cctcttgatt
    27121 tttgatatag taagacatga cttttataga ataaaaagga gacattatgg gatttccaac
    27181 aattttaatg tttgtagtga tgcttggatt gatttggttt atgcaacgtc aacaaaaaaa
    27241 acaagcgcaa gaacgccaaa accagttaaa cgctattgaa aaaggagacg aagtcgtaac
    27301 gattggtggc atgtttgcga ttgttgacga agtcgataca acagctaaaa agattgtgtt
    27361 agatgtggat ggcgtctttt tgacatttga gctatcagct attaagcgta ttgtaacaaa
    27421 agctaccaca gaaacgacac tggttgaaac agaagaaacc agtgttgtta atgagcctgc
    27481 tgttgagaca gtagatagca ctgacactga cagtgccatt gaaagccatt aaggcgggga
    27541 aagtttggat gaaatatgcc aaactttttt gttttgatcc ctggactgaa acagttattc
    27601 tgatgctaac aggttcatga aaagctgaca catctatcag aggataggtg aacattttgt
    27661 gaagataaga tctaattgat aaaaaacaag ccaaaaggcg tgaaatatga taaaatatga
    27721 gataagtatg cttatcaata aggaaaaaac atgtttggat taaaagcgaa atcaacaaaa
    27781 aaagttttgg ggagtatccc aaagcatatt ggaattatca tggatggtaa tggacgttgg
    27841 gccaaaaaaa gactaaaacc tagagtgttt gggcataaag ctgggatgga tgctttacaa
    27901 gaagtaacga ttactgcatc tgagttgggg gttaaagttc tgacagtcta tgccttttcg
    27961 acagaaaact ggtccagacc ccaagatgag gtgtctttta tcatgaattt accagtaacc
    28021 ttctttgaca aatatgtgcc tgtgcttcat gagaacaatg taaagattca aatgattgga
    28081 gagactagtc gtttacctga agataccttg gcagcgctaa atgcagccat cgacaaaaca
    28141 aaacgtaata cgggtttaat tttgaatttt gctctcaatt atggaggacg tgctgagatt
    28201 accagtgctg ttcgctttat tgctcaagat gtcttagatg ccaaattaaa tccaggagat
    28261 attacggagg atttgattgc taattacttg atgacagacc atctgccata tctctaccga
    28321 gaccccgatt tgattattcg caccagtggt gagctgcgtt tgagcaattt cttgccttgg
    28381 caatcagctt acagtgaatt ttatttcaca ccagtcttgt ggcctgattt taaaaaggca
    28441 gagctactaa aggccattgc ggattataac cgccgccaac gtcgttttgg caaggtctaa
    28501 aaggagatag ttatgaaaga acgtgttgtt tgggggggag tagcagtagc tattttccta
    28561 ccttttctca taataggaaa cctaccattc caattatttg taggcgtttt ggccatgatt
    28621 ggggtatcag aattactgaa aatgaaaaga ttagaagtct tttcttttga aggtgttttt
    28681 gccatgttag ccgcctttgt attggcagtt ccgatggacc attacctcac ttttttacca
    28741 attgatgcga atgttgcttt ttacagctta atggtttttt tcattttggc aggtactgtt
    28801 ttaaatagca gagcttattc atttgatgat gcggcctttc cgattgcaac tagtttttat
    28861 gttgggattg gttttcaaca tttgatcaat gctcgcctgt caggaattga caaggtcttt
    28921 ttggccttat ttatcgtttg ggccactgat attggagcat atctgattgg gcgtcagttt
    28981 ggtaggcgca aactattgcc tacagtttct ccaaacaaaa ccattgaagg tagtttagga
    29041 gggatcgctt gtgcagtcct tgtgtctttt atctttatgg tgattgatag gtctgtttat
    29101 gcgccacatc actttttgac catgttggtt ttggtcgctc ttttttccat ttttgcccaa
    29161 tttggtgatt tggttgaaag tgctctcaaa cgtcactttg gtgtcaaaga ttcaggtaag
    29221 cttatcccgg gacatggtgg tattttagac cgctttgatt ccatgatttt tgtttttccc
    29281 atcatgcatc tctttggttt attttaatct taagaggtaa tgtttggagt cgcaacaacg
    29341 cgacaaaact caaaaaagca atagactgaa aggaaatcta tgttaggaat aataaccttt
    29401 attattattt ttggtatttt agtgattgtc catgaatttg gacatttcta ttttgctaaa
    29461 aaatcaggca ttctagtaag agaatttgcc attggaatgg gccctaaaat tttttctcat
    29521 gttgaccaag gaggaactct ttataccttg aggatgttac ccttgggtgg ttatgtgcga
    29581 atggctggtt ggggtgatga caaaactgag atcaaaacag gtactccagc aagtttaacc
    29641 cttaatgagc aaggttttgt taagcgcatc aacttgtctc aaagtaagtt agacccaacg
    29701 agtctcccaa tgcatgttac aggctatgac ttagaagatc agctgagtat tactggcttg
    29761 gttttagatg aaaccaagac atataaggtc gctcacgatg ctactattgt tgaagaagac
    29821 ggtactgaga taagaattgc tccgcttgat gttcaatatc aaaatgctag tattggcgga
    29881 cgtttaatca ccaattttgc aggtcccatg aataatttta ttttagggat tgtggttttt
    29941 atcctcttgg tctttttaca aggtgggatg tcagatttta gtagcaatca tgtccgtgtt
    30001 caagaaaatg gagcagcagc taaggctggt cttcgagata atgaccaaat tgtcgcaatt
    30061 aatggttata aggtgactag ctggaatgat ctcactgagg ctgtagacct tgcaacacgg
    30121 gatctaggcc cgtcacagac cattaaggtc acctacaagt cacatcagcg cttaaaaacg
    30181 gtggctgtga aaccacaaaa gcatgcaaag acatacacga taggagttaa ggcgagtctg
    30241 aaaacaggat ttaaggataa gctcttaggc ggtctagaat tagcttggag tggggcgttt
    30301 actattttga atgctttgaa aggattgatc actggcttta gtctcaataa attaggtgga
    30361 cctgttgcca tgtatgacat gtccaatcag gctgctcaaa acggcttaga gtcagtctta
    30421 tctcttatgg caatgctttc gatcaattta gggatcttta acctgattcc gattcctgca
    30481 cttgatgggg gaaaaatctt gatgaatatc attgaagcca ttcgtcgcaa gcctatcaag
    30541 caagaaacag aggcctatat caccctagct ggggttgcta tcatggtcgt attgatgatt
    30601 gctgtgacat ggaatgatat catgcgcgtc tttttctaat caagataggt catcttaagc
    30661 tgaccttatc atgttaaaga tcgaaaaaga cctcaaccct aagatttgca agggttgagg
    30721 tcttactcaa aatgaaagga atacacattc aaattattga ataatcccgc ttcactctta
    30781 cttgatgttt ccagaagggt ttgaggataa ggggatgtat taaaacggaa taatctatga
    30841 aacaaagtaa actgcttatc ccaaccttgc gcgaaatgcc aagtgatgcc caggttatca
    30901 gccacgcgct tatggtgcgt gccggttatg tgcgccaagt ttctgctggt atctatgctt
    30961 atttaccact ggcaaatcgt accattgaga aattcaagac catcatgcgt gaagagtttg
    31021 aaaagatcgg tgctgttgaa atgttggcac cagctctttt gacagctgat ctctggcgtg
    31081 aatcaggccg ttatgagacc tatggagagg acctctataa gcttaaaaac cgtgataact
    31141 cagactttat cttgggtccg acccacgaag aaacctttac gactttggtg cgtgatgcgg
    31201 tcaaatctta caagcaattg cccttaaacc tttatcaaat tcagtctaag tatcgtgatg
    31261 aaaaacgtcc gcgtaatggc ttgcttcgta cccgtgagtt tatcatgaaa gacggctata
    31321 gtttccatca caactatgaa gatttagatg tgacctacga agattatcgt caagcttacg
    31381 aagctatttt taccagagct ggtctagatt tcaaagggat tattggagat ggcggtgcca
    31441 tgggggggaa agattcccaa gaatttatgg ccgttacacc agctcgtacg gaccttgatc
    31501 gctgggtggt tcttgacaag tctattgcgt caatggatga tataccaaaa gaggtcttag
    31561 aagatattaa ggcagaattg gctgcttgga tgatttcagg tgaagatact attgcttatt
    31621 caacagaatc aagctacgct gccaaccttg agatggcaac taacgaatac aaaccgtcct
    31681 caaaagtagc tgctgaagat gccttggcag aagttgagac accacattgc aaaacgattg
    31741 atgaagtggc tgcttttctt tcagtagatg aaacacaaac catcaaaacc ttgctttttg
    31801 tggcagataa tgaacctgtt gttgctttgc tagttggaaa tgaccatatc aataccgtta
    31861 aattaaaaaa ctatctagct gctgattttt tagagccagc tagtgaagaa gaagcccgtg
    31921 ctttctttgg tgcaggtttt ggctcacttg ggcctgtcaa cttggcacaa ggtagtcgca
    31981 ttgtggctga ccgcaaagtg caaaacctta ccaatgccgt tgcaggagct aacaaggatg
    32041 gtttccatgt gacaggagtc aatccaggac gtgacttcca ggctgaatat gtagatattc
    32101 gtgaagtcaa agaaggggaa atgtctccgg atggtcatgg tgttctccag tttgcacgtg
    32161 gtatcgaagt cggtcatatc ttcaagttgg gcactcgtta ttcagacagc atgggagcaa
    32221 cgattcttga tgaaaatggc agaacagttc caattgtgat gggttgttat ggtatcgggg
    32281 ttagccgcat tttgtctgct gtcattgaac agcatgcccg tctctttgtg aacaagacac
    32341 caaaaggcga ttaccgttat gcttggggta ttaacttccc taaagaatta gccccatttg
    32401 acgtgcattt gattacagtt aatgtcaaag atcaagtggc ccaagacttg acggcgaagt
    32461 tagaagctga cttgatggct aaagggtatg atgtcttgac agatgaccgt aatgaacgcg
    32521 tcggttcaaa attctctgat agcgatttga ttggtttgcc aattcgtgtc actgttggta
    32581 aaaaagccgc tgaaggtatc gtggaaatta aaatcaaggc aacaggtgac agcattgaag
    32641 ttaatgcaga aaacctcatc gaaacccttg aaattttaac aaaagaacac taaaaaagaa
    32701 atgaagaggc tgcctgttta gagtggcctc tttttgctgt gaacttgtct gatacagagt
    32761 ggcttttgct ttaccaaaag cgcttggcga caaaagattg gcaaaaaaat gacctcagct
    32821 gagctatcac ttggaataaa ttagccaaag aacgtcagaa gaaagccctg cttttctttc
    32881 catctaaaac tcgaaaatca tcttgaattg tgataaaata aagcctagta aaatcaggag
    32941 aaaattatgt cagatttatt cgctaaattg atggaccaga tagaaatgcc acttgacatg
    33001 agacgttcaa gtgccttttc atctgctgat attatcgagg taaaggtgca ttcggtgtca
    33061 cgcttgtggg aatttcattt tgcctttgcg gcggttttac cgattgcaac ttatcgtgaa
    33121 ttacatgatc gtttgataag aacttttgag gcggctgaca ttaaggtaac ctttgatatc
    33181 caagctgctc aggtggatta ttcagatgat ctgcttcaag cttattacca agaagctttt
    33241 gagcatgcac cgtgtaatag tgctagtttt aaatcttctt tctcaaagct caaagtgact
    33301 tatgaggatg acaaactcat tattgcagcg ccaggttttg tgaataacga tcattttaga
    33361 aacagtcatc tgcctaatct ggtcaagcaa tttgaagcct ttggctttgg caccttgacc
    33421 atagatatgg tgtcagatca ggagatgact gagcatttga ccaaggattt tgtttccagt
    33481 cgtcaggctc ttgtgaaaaa ggctgtgcag gataatttgg aagcccaaaa atcccttgaa
    33541 gccatgatgc caccagttga ggaagccaca cctgctccta agtttgacta caaggaacga
    33601 gcagctaagc gtcaggcagg gtttgaaaaa gcgaccatca caccaatgat tgagattgag
    33661 accgaagaaa accggattgt ctttgagggt atggtttttg atgtggagcg taaaacgact
    33721 agaacaggtc gccatatcat caactttaaa atgacagact atacctcctc gtttgctctg
    33781 caaaaatggg ccaaagacga tgaggagctc cgtaaatttg acatgattgc taagggagct
    33841 tggttacggg tacaagggaa tattgagacc aatcctttta cgaagagtct caccatgaat
    33901 gtgcagcagg tcaaagaaat tgtccatcat gaccgcaaag acctgatgcc agaagggcaa
    33961 aagcgggtcg aacttcatgc ccacaccaat atgtctacca tggacgcctt accgacagta
    34021 gaaagcttga ttgatacggc agccaagtgg ggacacaagg cggttgctat taccgaccat
    34081 gctaatgtgc aaagttttcc tcatggctac catagggctc gcaaagctgg aattaaggct
    34141 atttttggcc tagaagccaa tattgttgag gacaaggtgc ctatttctta tgatcctgtt
    34201 gatatggatt tgcacgaagc tacctatgtg gtctttgacg tggaaaccac aggtctatct
    34261 gctatgaata atgacctgat tcagattgcg gcttccaaaa tgtttaaagg caatattgta
    34321 gagcagtttg atgaattcat tgatcctggg catcctcttt ctgcctttac caccgaattg
    34381 acagggatta ccgataagca tttgcaggac gccaagccat tggttaccgt cctaaaagct
    34441 tttcaggact tttgcaaaga tagtatcttg gttgcccaca acgccagttt tgacgtgggc
    34501 tttatgaacg ccaattatga acgccacgac ttgcccaaaa tcacacagcc tgtgattgat
    34561 accttagaat ttgctagaaa cttgtatcct gagtacaagc gtcacggttt gggaccgctc
    34621 accaagcgtt tccaagtgag tctagaccac catcatatgg ccaattacga cgcggaagcc
    34681 acaggacgtc ttttgtttat ttttctaaga gatgccagag aaaagcatgg catcaaaaat
    34741 cttttgcaac tcaatacaga tttggtagct gaggattctt acaaaaaagc gcggattaag
    34801 catgcgacta tctatgtgca aaatcaggtt ggccttaaaa atatgtttaa gttggtcagc
    34861 ctttccaata ttaaatattt tgaaggggtg ccgcgtattc caagaaccgt cttagatgct
    34921 cacagagagg gtttgttact tggtacagct tgttctgacg gcgaggtttt tgatgccgtt
    34981 ctgactaaag gaattgatgc ggcggttgat ttggctaagt attatgattt tatcgaaatc
    35041 atgccaccag ccatttacca gccattggtt gtccgtgaat taatcaaaga ccaagcaggt
    35101 attgagcagg tgattcgtga cctcattgaa gtagggaaac gagctaataa acctgtactt
    35161 gccactggaa atgtgcatta cctagagcct gaagaagaga tttaccgtga aattattgtg
    35221 cgtagtctcg gtcagggtgc catgattaat agaacaatcg gccgtgggga aggggcccaa
    35281 cctgctcccc tacctaaagc gcactttaga acaaccaatg aaatgctgga tgagtttgcc
    35341 tttcttggaa aagacctcgc ttatcaagtg gttgtagaaa atactcagga ttttgcggac
    35401 cgtattgagg aagtggaagt ggttaagggc gatctttaca ccccgtatat tgacaaggcc
    35461 gaagagacgg ttgccgaatt aacctatcaa aaagcctttg aaatttatgg taatcctctc
    35521 ccagatatta ttgatttacg cattgaaaaa gagttaacct ctatcttggg gaacggtttt
    35581 gctgtgattt atctcgcttc ccaaatgctt gttaaccggt caaatgagcg aggctatctg
    35641 gttggctcta ggggatctgt agggtctagc tttgtcgcca ccatgattgg gattactgag
    35701 gttaatccta tgccgcctca ctacgtttgc ccgtcctgcc aacattctga atttatcaca
    35761 gatgggtcag ttggatctgg ctatgatttg cctaataaac cctgtccgaa atgtggcacc
    35821 ccttatcaaa aagatgggca agacattccc tttgagacct ttcttgggtt tgatggggat
    35881 aaggtgcccg atattgattt gaacttctct ggtgatgacc agcccagtgc ccatttggat
    35941 gtccgagata tttttggtga cgaatacgcc tttcgtgctg gaacagttgg taccgtagca
    36001 gaaaaaacag cttatggatt tgtcaaaggc tatgaacgcg actatggcaa gttctatcgt
    36061 gatgctgagg tggatcgtct agcagcaggt gctgctggtg tgaaacgaac gactgggcag
    36121 caccctgggg ggattgttgt tattcctaat tacatggatg tttatgattt tacccccgtg
    36181 caatatccag cagatgatgt aacggcttct tggcagacaa ctcactttaa cttccatgat
    36241 attgatgaaa acgtcttgaa acttgatatc ctagggcatg atgatccgac catgattcgt
    36301 aaacttcagg atttatcggg cattgatcct attactatcc ctgctgatga tccaggtgtt
    36361 atggctctct tttctgggac agagattttg ggcgttaccc cggaacaaat tgggacaccg
    36421 actggtatgc taggcattcc agaatttgga accaactttg ttcgcggcat ggttaatgag
    36481 acgcatccga ccacttttgc ggagcttttg cagttgtctg gactatctca tggaaccgat
    36541 gtttggcttg gtaatgcaca agatttgatt aaagaaggca ttgcgaccct aaaaaccgtt
    36601 atcggttgtc gtgacgacat catggtttac ctcatgcacg caggcttaga accgaaaatg
    36661 gcctttacca ttatggagcg tgtgcgtaag ggcctctggc tgaaaatttc tgaggaagaa
    36721 cgtaatggct atattgatgc catgcgagaa aacaatgtgc ccgactggta cattgaatcg
    36781 tgtggaaaaa tcaagtacat gttccctaaa gcccatgcgg cggcctatgt cttgatggcc
    36841 cttcgggtgg cttatttcaa ggtgcaccac cccattatgt attattgtgc ttatttctct
    36901 attcgtgcga aggcttttga attaaaaacc atgagtggtg gcttagatgc tgttaaagca
    36961 agaatggaag atattactat aaaacgtaaa aataatgaag ccaccaatgt ggaaaatgac
    37021 ctctttacaa ccttggagat tgtcaacgaa atgttagaac gcggctttaa gtttggcaaa
    37081 ttagaccttt acaaaagtga tgctatagaa ttccaaatca aaggagatac ccttatccct
    37141 ccatttatag cgttagaagg tctgggtgaa aacgtggcca agcaaatcgt taaagctcgt
    37201 caagaaggcg aattcctctc taaaatggaa ttgcgtaaac gaggcggggc atcgtcaacg
    37261 ctcgttgaga aaatggatga gatgggtatt ttaggaaata tgccagaaga taatcaatta
    37321 agtctttttg atgacttttt ctagattatc atgatggtag tcatatgcaa agtcataaaa
    37381 gaagagggac aagatcactt tctaatctct ctgatactaa attgtgacat accgtataaa
    37441 gcgaggaaat caaatgagtc atttagataa gaacaccgct ttgaaagcca tggtggtgtt
    37501 tcgtaaagct cagcgaacgc tagatgcttt tggggctgat atttttaaaa aggcagattt
    37561 aacagccacg cagttcagtg tgcttgaagt actatatact aaaggctgta tgcgaatcaa
    37621 tcacttgatt gattctttgt tagcgacttc ggggaatatg actgttgtac taaataatat
    37681 ggaacgtaat ggctggatta gcaagtgcaa agacaaaacg gataaaagag cctatgtggt
    37741 taccttaaca gataagggta ctcgcttgat tgaagctgtt ttgcctaaac acgtcgcacg
    37801 ggtggaagaa gcctttgctg ttttgactga aaaagaacaa ctttgtctga ttgaacttct
    37861 caaaaagttc aaacaattat aaacaaatct ctttacagct cttcttagag aagatataat
    37921 tactacatag tgataaattt caaaaagaag tatcaatgaa ataccacttt tagaaagctt
    37981 taaaacgatc tttaaaaaaa gaggacaaag agatgaaaca tattttattt attgttggct
    38041 cgcttcgtga agggtctttt aaccatcaat tagcggctca agcacaaaaa gctctggaac
    38101 atcaagcagt agtatcttac ttaaattgga aagacgttcc tgttttgaat caagatatcg
    38161 aagctaatgt acctttacca gttgttgacg ctcgtcaagc tgttcagtca gcggatgcta
    38221 tctggatttt tacaccagtt tacaacttct ctattccagg ttctgttaaa aacctgctag
    38281 actggttgtc tcgtgctctt gatttgtctg atccgacggg cccatctgct attggcggta
    38341 aggtggttac ggtctcttca gttgcaaatg gcgggcatga tcaagtattt gatcagttta
    38401 aagcactatt gccgtttatc cgaacttcag tagcaggaga gtttacaaaa gcaactgtga
    38461 atcctgatgc ctggggaaca ggaaggcttg agatttcaaa agagacaaaa gcaaacttgc
    38521 tatctcaggc agaggctctt ttagcggcta tttagactaa caaaaaaagg ctaaagggcc
    38581 ttttttgtta gtctaaaatc aagagctctt ctttggtttc aaaggggttt ttagcattga
    38641 tccgatcgta gaacaaaaca ccattgatat ggtcaatttc atgttgaacc acaatagcgt
    38701 tgtatccctt taatttgatg cgatgctgtt gtccttcttt atcatagtag tctactgtaa
    38761 cacgagcatg gcgaaccaca tacccttcaa caacacgatc gacagataaa caaccttcgc
    38821 catcagaaag ggctgcatct tgaacagaat gagaaacgat tttaggatta tacaggactt
    38881 cttgccagct ataggcttct ttaggaggat ttccttcttt atcaggaaga ttaggaacga
    38941 gcacagcgat gatacgtttt gacacatcaa tctgaggagc tgctagacca acaccggccc
    39001 taagtccaag tttttccgcc attacaggat cttgagaatg cttcaaaaat tgcatcatct
    39061 tttctcctaa taggatatcc tcatcacaca agggtaagct cacttctttg gcgacagctc
    39121 ttaaagttgg attcccttca cgaataatgt catccatggt aatcagatga ctaggtttaa
    39181 ttaatttatc ttgtgcagac atgtctactc ctttactttt ttttaactgg atttactata
    39241 tcacaaatca tttctttttt aaagaaaagt caggtagtgg tcagagtgat tgctattata
    39301 agttaatggg ctgcatacct cagaggtcta gttattaaca cttaattgag ttagagcgtc
    39361 taaatcggca atacgacagg ttttgaagca gatgcgttcg ataatcctct gaaaaatggg
    39421 ctgcttaagt acgtgcttaa gatggcgatc gcttgttcca aaacggtttg ctaataatgt
    39481 aaggtttaga tgaacctctt ggttggcttg cgcttcaagg gtataggaag caaagcgctc
    39541 tttgacggta taggtaatgt tttgttggca aacattttgt gtcaactctt gacctatgtc
    39601 ataaaggcag gtcgcatcgg ttaataagct gtgttcatgg attagggatt gggtttgtta
    39661 atactagagc aattaatatt atcagtgaac actttgttgg aaagaaatga atgactatgc
    39721 taggttaccg cttatcagct gaagtgcggg gatcagccat cttacctctt ttagctggtt
    39781 atcttattag gcaagcaatc gcacaggttt attctgattt aaaaacagcc tcttggctat
    39841 ttggccttgc tagttctgtt gcttaaggtg gtttggatgt gagagcttag aataatagga
    39901 taacggttga cctaatatta tgaatctgct agaatagagt ggtcgaaaga caaaccaact
    39961 ttttcttggt tttaggagtg ccaatcctaa gactcggatt aagcaaaaaa aggagaatat
    40021 attatggcaa tctcaaaaga gaaaaaaaat gaaatcattg ctcaatatgc acgtcacgaa
    40081 ggcgatactg gttcagttga agttcaagta gcagttctta catgggaaat caaccacttg
    40141 aacagccaca tcaaagaaca caaaaaagac cacgctactt accgtggatt gatgaaaaaa
    40201 attggtcacc gtcgtaactt gttggcatac ctacgtcgta cagatgttaa ccgttaccgt
    40261 gagttgatcc aatctcttgg acttcgccgt taatttcaag tttaaaaagt cctctgctta
    40321 tgcagtgggc tttttcattt ttgacatgtt gtttgttaac ttacacattt ggctagaatg
    40381 gtctaagact gtttttttaa gcagttgatg attttattta acaacaaaag gtatctcagt
    40441 gatgaggtat cttttgttgt atcatgaaga aaaagggaat caattcccag atttgcctat
    40501 ttttggccac cttttgagga acttgttaca atgatatcac ctgttgagtc caattgcagt
    40561 caaaaatgac tacggacaat tggactcaat ttgtcttgaa aatgaaaacg cttcatttta
    40621 tactgacatt ataggaggag atgacatgct atctcatgag ctcatcagaa actatcaact
    40681 cttttctaaa tataaaggac attcactgga ggcatttgaa tccatattaa agacaagcaa
    40741 acgtcatata ctggcagata ttgctaaaat caatgacacg ttgtcactct atcagttacc
    40801 ccttattgct ctggacaggc agctggttta tccgccagac cttactgaaa aggacttgtt
    40861 gaatcgcatg ctacctacct tagacgacta tctctttcaa gatgagcgtc tggacatgat
    40921 tatcatttac atcatgatgg ctaaagaatt tatctccatt aaccacttgg aaagcttgtt
    40981 acggctcagc agaaattccg ttattgctga tttaaacttg gtgcgtgatc gggtacaagc
    41041 ttttcaggta actttagctt acaatcgcca ggatggttat ttttttgaag gagaaccctt
    41101 agccttgcgg cgtctcttag aatcagcggt cagttctctt ttgcaagtta catcaggacc
    41161 ttgggtgttc agttacttat tgcatgaact tggtttgccc gaccagacaa aggtgatggc
    41221 agcaacgttg gaggaactga gcagggagaa ccacttaact tttatttcgg agaaattgag
    41281 ggatttgatt tattttttct gccttctcgc tcatcgacca ttttcacgga acgtaagggc
    41341 tgaagtagtg gatacttttc ctttagcttc gccagctgtt gaaacgatgg tggaccagtt
    41401 attggtcaac ttccccagtc taaccgaaga gaaatatttg gttcaatcta ggttacttgg
    41461 ttgtatccaa ggtgacttag agttagtctt tcagcaacct atttatgaca ttatggagga
    41521 aatcatcaat tcggtggcgg ttaacacggg attgtctatc accgataccc cagaacttcg
    41581 tcagaaccta tacagtcacc ttttgccagc ttattaccga ctttactacg acattaactt
    41641 gaccaatcct ttgaaggaac aaatcaaaca agattatgaa tctctctttt acttggtcaa
    41701 gcgcagcctt tctcctctag aaaaacaatt ggggaaacca gttaatgaag atgagattgc
    41761 ttattttacc attcattttg ggagatggtt gcaggcccct aagaagaggc cgagcaatca
    41821 gctggtagcc ttatctgttt gccctaatgg catcagttcg tctctgatgt tggaggcaac
    41881 cttgaaggaa ctttttccac agctacagtt tattaggatt caccagctgg acaaaataaa
    41941 gttgttggat ccagcttcct ttgatttgat tttttcaaca gtagcttttg actgtgttaa
    42001 acctgtttat gtgacgcaag ctttgatggg acctgttgaa aaaatgatgt tgaaaaagat
    42061 ggtctgtgat gactttcatc ttcccttgtc agagcaattc gctttggatg acctgttgag
    42121 tattattcat aaacacacca cgattactaa taaagaagga cttgttagtg atttatcccg
    42181 ttacctgttt ggtaaccatt taacgattga aaaaggaggt ctaggactat tggacttgtt
    42241 aacagcagat tttattaggc aggctgatgc tgtttcggat tggcaggaag cgattcgttt
    42301 ggctgctcag cctttactag aacaccagat gattgaaaca tcttatatcg acggtatgat
    42361 tgattcggtc aatgagcttg gagcctatat tgttttagcc cctaaggtgg ctgttcctca
    42421 tgcggcgcct gaaaaaggaa cgcggcagtt aggcatgtct ctcttacaac taaaagaacc
    42481 tgtcagcttt gatttgaagc aagaaggtga tccagacaag caagtgcaat tgatttttgt
    42541 tttgtctgct gtggattcta gttcacattt gaaggctttg caggaactgt cgttgatttt
    42601 agatgatgat gaacatattg agcaattaat tgaggctaag aatactgagg aaataatgag
    42661 tctgattagc catatgattg aaaaaggaga tgaatcacat gattaaaatt gtaacggttt
    42721 gtggaaacgg tattggtagt agcttgttac ttcgcatgaa agtagaagct atcgcctcta
    42781 gtttgggtat tgatgtggat gcagaatcct gtgattccaa tgcggctgtt ggaaagggtg
    42841 cagatttgtt tgttaccgtt aaagaattta aagatatttt tccagaggat gccaaggttt
    42901 gtatcgttaa aagctatacc aatcgtaaaa aaattgaaga agatttggtt ccggttctca
    42961 aggaaatgag tggcaaggaa taagccttta aaggagatag gaagatacta tggaagcatt
    43021 attatcattt attcgagata ttttaaaaga acctgcattt ttaatgggct tgattgcctt
    43081 tgcagggttg gtggctttga aaacacctgc tcataaggtg ttgacaggaa ccttggggcc
    43141 gattttggga taccttatgc ttgctgcagg ggcgggtgtt attgtgacca atctggaccc
    43201 tcttgccaaa ctcattgagc acggttttag catcactggc gtagtgccaa ataatgaagc
    43261 cgtcacttct gtcgctcaaa agattctggg tgtggaaact atgtccatct tggtggttgg
    43321 gttattgctt aatttggctt ttgctcgttt tacccgcttc aaatacattt tcttaacagg
    43381 acatcacagc ttctttatgg cttgtctctt gtccgccgtg cttggagctg ttgatttcaa
    43441 aggaagtctt ttgattatct taggtgggtt cctcttggga gcttggtcag ctatttcgcc
    43501 agccattggt caacagtata ctctgaaagt gactgacgga gatgaaatcg ccatgggaca
    43561 ctttggtagt ttgggctatt acctttctgc ctgggttggt agcaaggttg gcaaagacag
    43621 taaagatacc gaggaccttc agatttctga aaaatggagt ttcttacgca acaccaccat
    43681 ttcaacagga cttatcatgg tgcttttcta cttggtggca acagtggctt ctgttttgag
    43741 gaatacttca gtaacagaag aattagcagc aggtcaaaac ccatttatct ttgctattaa
    43801 gagtggtctt acctttgcgg ttggtgtggc aattgtctac gccggtgttc gcatgatttt
    43861 ggctgacttg attccagcct tccaaggtat tgctaacaaa ttaattccaa atgctattcc
    43921 agccgtggat tgtgcggtat tcttccctta tgcgccaacc gctgttatca tcggttttgc
    43981 gtcaagtttc gttggtggct tacttgggat gttgatttta ggagttgcag gtggtgtcct
    44041 gattatccca ggtatggtgc ctcatttctt ctgcggtgca acagcaggga tttttggaaa
    44101 ttcaacaggt ggtcgtcgcg gtgcaatgat tggtgctttc gctaatggct tattactcgc
    44161 cttcttgcca gccatgcttc tacctgtact tggtaaactt ggtttttcaa acacgacctt
    44221 tggagatgtg gatttcggtg ttttagggat tttactgggc cgcttaggaa cgtcgattgg
    44281 tcaaatcggt atttacttgg tggttgctgt gcttgctatt gtattggtgc ttccaaactt
    44341 tctgtcaaaa tctcaagaag ccatcaataa tgtttcagaa gaaatctaaa aggaggatat
    44401 gatgacaaaa aaactaaacg ttaaagtctt ttcagacggt gcggtcttag agaccatgtt
    44461 aaaggattta caaacaggtt tggtcacagg ctttacaacc aatccaagtt tgatgaaaaa
    44521 agcaggcatc agttcttata ttggctttgc caaagaagtg cttgccaaaa ttacagacta
    44581 cccagtgtcc tttgaagtct ttgcggatga tctcgcaagc atggaaaagg aagctgagaa
    44641 aattgccagt ctaggtgaca atgtctatgt gaaaattcca gtcaccactt caacaggcga
    44701 atcaacttgt cccgttattc aaaagttgtc agccaaaggc attaagttaa acgtcacagc
    44761 catttttaca attgagcaga ctcaagctgt ggttgatcat ttaaccgctg gagtgccagc
    44821 tattgtgtct gtttttgctg gtcgtattgc agacaccggc gttgacccaa tgccaatcat
    44881 ggaagaagct ctacgcattt gtcgtcaaaa agaagaggtc gaattgttgt gggctagtcc
    44941 tcgtgaaact tataatatct atcaagctga tcagttaggc gtggacatta tcacttgtac
    45001 cactgatttg attgccaagt tgcctcttca aggaaaagat ttagaagact attcccttga
    45061 aaccgtgcaa atgtttctga aagacagtac cagcctcggc tttaaaattt tagaggatga
    45121 caatcattaa tattaggaga cgaaagcagg cataccaacc tgcttttttt gctttgttaa
    45181 agagtataag tttcgtttaa tatttttcaa ggacatttca agagattgcg atctgacagt
    45241 gaaatttctg ctattttatg gtaaaatgta gcagatacgt cgtttgatac aaagaggagc
    45301 gtgtgacaag cgtggcaggt tgctttttgt agcaaaacaa cgtataacaa ctgaatctaa
    45361 gcagagaaca ggtacctctt tacccctctg aaaattaaaa ggagaatata tgtcaaaaca
    45421 aacctttaca acaacatttg cagggaaacc ccttgttgtt gaagttggtc aagtcgctaa
    45481 gcaagccaac ggggcaaccg ttgttcgtta cggagaatca accgtcctga ccgcagctgt
    45541 tatgtctaag aaaatggcaa cgggtgattt cttccccctt caagttaatt acgaagaaaa
    45601 aatgtatgcc gctggtaaat tcccaggagg tttcatgaag cgtgagggac gcccttcaac
    45661 agatgcgacc ttgacagctc gcttgattga ccgcccgatt cgtcccatgt ttgccgaggg
    45721 ttttcgtaac gaagtacaag tgattaacac tgtcctttct tatgatgaaa atgctagcgc
    45781 tccaatggca gcgatgtttg gctcatctct ggccttgtcc atctcagata ttccatttaa
    45841 tggaccgatt gcaggtgttc aagttggcta tattgatggt gagttcatca ttaacccaga
    45901 taaagaacag atggaagcgt cactcttaga attaaccgtt gctggtagca aagaagccat
    45961 caacatggtt gaatctggtg ccaaagaatt atcagaagac atcatgcttg aggctctttt
    46021 aaaaggtcac caagccattc aagaattaat tgccttccaa gaacaaatcg tagcagttgt
    46081 tggtaaagag aaagctgagg ttgaactgtt acaggttgat gcagacttac aagctgatat
    46141 tgtggctaag tacaatgctc aactgcaaaa agctgttcaa gttgaagaga aaaaagcgcg
    46201 tgaagcagcc acagaagccg ttaaagaaat ggttaaggct gagtacgaag agcgttacgc
    46261 agaagacgaa aacctagcaa ccattatgcg tgacgtggca gaaatccttg aacaaatgga
    46321 gcatgctgaa gtgcgccgcc tcattacaga ggacaagatt cgtcctgacg gtcgtaagat
    46381 tgacgaaatt cgtccgcttg atgctgtggt tgacttcttg ccaaaggtcc atggatcagg
    46441 tctttttacg cgcggtcaaa ctcaggcgct atcaattttg accttggcac caatgggaga
    46501 aactcaaatc attgatggtc tggccccaga gtacaaaaaa cgcttcttgc atcactacaa
    46561 tttcccgcaa tattcagttg gtgaaacggg tcgttacgga gctgctggtc gtcgtgaaat
    46621 tggacacggt gccttaggtg aacgcgctct tgaacaagtc ttgccaagct tagaagagtt
    46681 tccttatgcc attcgtttag ttgccgaagt tctagaatct aacggttcgt cttctcaggc
    46741 ttctatctgt gctggtaccc ttgctctgat ggctggtggt gtaccaatca aggctcctgt
    46801 ggcagggatt gccatgggtc tcatttcaga cgggacgaat tatacagtct tgaccgatat
    46861 ccaaggtctt gaagaccact ttggagatat ggactttaaa gtggcaggaa ctcgtgaagg
    46921 gattacagcc cttcaaatgg atattaagat tgcagggatt acgcctcaaa tcctagaaga
    46981 agctcttgca caagctaaaa aagctcgctt tgaaatcctt gatgtgattg aagcaactat
    47041 cgctgaacca cgtcccgagt tagccccaac tgcaccgaaa attgacacca tcaagattga
    47101 cgtagacaaa atcaaagtgg ttatcggtaa aggtggcgaa accattgata agattattgc
    47161 cgaaacgggt gtcaaaattg atattgatga cgaaggaaat gtctctatct actcaagtga
    47221 ccaagctgcc attaaccgca ctaaagaaat catcgctggc ctagtacgtg aagctaaggt
    47281 aggcgaagtt taccatgcta aggttgtccg tattgagaaa tttggtgcct ttgtcaacct
    47341 ctttgacaag acagatgcac ttgttcacat ttctgaaatt gcttggacta gaacgaccaa
    47401 cgtgtcagat gtccttgaag tgggtgaaga cgttgatgtt aaggtcatta agattgatga
    47461 gaagggtcgt gtggacgcct caatgaaagc tttgattcca cgcccaccaa aaccagagaa
    47521 aaaagaagaa aaacatgact aaatcaaatg aattagatat tcgcttaaga gcttttatca
    47581 atgcgcctga taactttttg gatagtgttg cccttgtcaa tgctttccat aattttcctg
    47641 tctgggctgc taaagaaccc tacgtgatag aagtcgaagg tgtcaaggtt acccctgttt
    47701 ttaccgataa ggaagatatg gctcgcttta aagaagaaca agagagtgct caaagtcagt
    47761 attggctgga gcgttcagct cttgcagtgc tagaagaagt cattacatct ggtgcagcag
    47821 gtcttgtctt taaccttaag aaaaagggag attttgggaa ttctaccatt ttcaaaagca
    47881 gtgatatgat tcaatttatg aaccattaca ccactgtgtt aaatacgctt atgagtgatg
    47941 acaatgtggc ggcagatacg atggaaaagg tttaccttgt tcctgccttt gtttatccta
    48001 aagataataa ccattacgac cgcctttttc ctaccatgtc aacgcctgaa ggaaaaagct
    48061 atgttcccgc cttttcaaat cttcaaagct ttgcgaaatg gtacaaccaa gacgattttg
    48121 gaggcctttt caggaaagct gaaggagtga ttctgacttg gacgattgat gatatttatc
    48181 aaccaagaaa tggtgaaaac gagcttgatg aaacgttcgg tgtcgccatc aatccttttg
    48241 atgaccaaca aattcttgtt gattggtcag aattagataa gtcgtaggag ttagtatggg
    48301 ttggtggaaa gaaagtatag ctattgttaa agctctagac ccagctgctc gtaatagtct
    48361 tgaggttatc ctaacttatc caggcatcaa agccctagct gctcatcgtt tgtctcattt
    48421 tctttggcga catcatttta aattactagc cagaatgcat agccaatttt ggcgattttg
    48481 gacacaaatt gaaatccatc ctggagcaca aatcgctcct ggagtcttca ttgaccatgg
    48541 tgctggtctt gttattggag agacagcaat tgttgaaaaa ggtgtgatgc tttatcatgg
    48601 ggtgacccta ggtggaaccg gaaaagattg tggcaagcgt catccaacgg ttcgacaagg
    48661 tgccttaatt tcggcacatg cccaagtgat tggacctatt gacatcggag caaatgctaa
    48721 agtaggggca gcagctgttg tgttatcaga tgttcctgaa gacgtgacag ttgtaggtgt
    48781 gccagctaag atagtacgag tgcatgggca aaaagataat cgtcaaattc aaagtttaca
    48841 aaaacaacga gaggtctctt atcagttgtc aaaatgatcg gaaaataaca aaaagaagca
    48901 ctgatgactt ccgataaaat attttgggac tttctagtag agtaatgttg aacttagcta
    48961 gccctatcag tttggttgct gagtgtagtg atatgggaat gttacaaaat acaaaaaaca
    49021 cgtaaaagag catcaactaa gcaagtctta gactgaagaa acagtctatt gtgatacttt
    49081 ttctcaggtg gtgcttacgg cagcgacttc ctttggaatt ccatgcctta gttttgagcc
    49141 taaggtctca aaaatctgta tgggcatcac tgtcagtatt gataccactt ttaccacaac
    49201 aaaaagcagc tgttttggct caccccacat gcagaaatag gaaacctgat gtcaaatcag
    49261 cagatctatt catgcttttt gagcataaaa gtgggtttgt ctactttctg aagccttcac
    49321 aggttgtgaa ggtttttcgt taataaagga gcctcatgaa taaaataaga gttgggctgt
    49381 atgtcattat gagtttgtct attcttgttt ctagtattac actggtggct agtctaatct
    49441 ttttactgag acaagacatg gttaaagcga ttatatactt cattttgacc ctattttggt
    49501 taataggttt ggttattaat attaaattgt tgaaaaggtg gaatagcatt tcagaaaaag
    49561 acttaggata tcaagatgac aactaatgct aggatattga ataaggagtt tacatgatta
    49621 aaatttatga taccatgacc cgttcgctcc gcaagtttgt acctttgact gaaaatacag
    49681 tcaatatgta cgtttgtgga ccgacggtct ataattatat tcatattgga aatgctagat
    49741 cagcggtcgc ttttgacacc attcgacgtt attttgagta tactggctat caggtcaatt
    49801 acatttccaa ttttaccgat gtcgatgata aaattatcaa ggctgctact caagcaggtg
    49861 tttctcctaa agaattgtca gatcgcttta ttgcagcttt tatagaagat accaaggcac
    49921 ttggtgttaa gccagccaca caaaatcctc gtgttatgga ttatatagca gaaatcattt
    49981 catttgttga aagcctcatt gaaaaagatt ttgcttacga agcagatgga gatgtgtatt
    50041 tccgcgtgga aaagtcagag cattatgcca agctagctaa taaaaccctg tcagaacttg
    50101 aagttggagc cagtggtcga acagatgctg agacagcttt aaaagaaaat ccactggact
    50161 ttgctctttg gaaatcagct aaggcaggtg aggtttcttg ggatagcccc tgggggtttg
    50221 gtcgtccagg ctggcacatt gaatgttctg tgatggctac tgaaattctt ggtgatacca
    50281 ttgatattca tggtggcgga gctgatttgg aatttcctca tcataccaat gaaattgccc
    50341 aatctgaggc taaaacaggc aagacttttg ctaactattg gatgcacaat gggtttgtca
    50401 ctgttgataa cgaaaaaatg tccaagtcac taggtaattt tgtgaccgtt catgacatgt
    50461 tacaaaccgt tgatggtcag gttttgcgat tctttcttgc gacacaacag taccgaaaac
    50521 caattaactt cactgaaaag gctattcatg atgcggaaat caatctgaag tatcttaaaa
    50581 acaccttgca acaaccgctg acagaaactg cagatgagca agagctaaaa cagtttgtaa
    50641 tagctttcca agacgctatg gacgatgatt tcaatacagc aaatgggatt accgtcgtat
    50701 ttgacatggc taagtggatt aattctggct cctatacaga acctgttaaa agcgcttttg
    50761 agaaaatgtt agctgttttt ggcattatct ttgaagaaga ggtgcttgag gttgacattg
    50821 aagccttgat tgctaagcga caagaagcac gcgcgaatcg tgattttgcc atagctgatg
    50881 ccattcgaga tcagttagca gctcaaggca tcaagctgct agataccaaa gatggtgtga
    50941 ggtggctgcg tgattaatcc agttgatgtg aatttgatta atggcattgc cctagccttt
    51001 gaaggagatg cggtttattc ctactatgtt cgtcgtcatc tcatttttca aggtaaaacg
    51061 aaacctagcc agctacaccg tttagcaacg agatatgttt ctgctaaggc acaagccaac
    51121 ttgattcagg ctatgttaga agcgcagcta ttgaccgaaa aagaagaaga catctataag
    51181 cgtggtcgca ataccaatag ccatactaaa gctaagaatg ccgatattat tacctatcgt
    51241 atgtcaacag gttttgaagc cattatgggt tatcttgata tgatgggcca aaaagagcgg
    51301 ttagaagaat tgatcagatg gtgtattgag tatgtagaaa agcaacaatt gatatcctca
    51361 taagagtccc ctaggagact cttattttca taggtctgaa gtaaaggtag agagccatta
    51421 actcttttta tgacatcaaa aagacataat gatataaaaa agatacattt gtaacaaaaa
    51481 agacataaaa ataatgaaat cattttcgaa tagtttataa tgagagggta agactaattt
    51541 aaagaggaga tatttattat gacaactatg caaaaaacag ttagcttatt atcactagct
    51601 ttacttattg gtttgctggg gacttctggc aaagccatat ctgtgtatgc acaagatcag
    51661 cacactgata atgttatagc tgaatcaact attagtcagg tcagtgttga agccagtata
    51721 cgtggaacag aaccttatat tgatgctaca gtcaccacag atcaacctgt cagacaacca
    51781 actcaggcaa cgataacact taaagacgct agtgataata ctattaatag ttgggtatat
    51841 actatggcag cgcaacagcg tcgttttaca gcttggtttg atttaactgg acaaaagagt
    51901 ggtgactatc atgtaactgt caccgttcat actcaagaaa aggcagtaac tggtcaatca
    51961 ggaactgttc attttgatca aaacaaagct agaaaaacac caactaatat gcaacaaaag
    52021 gatacttcta aagcaacgac gaattcggtc gatgtagaca caaaagctca aacaaatcaa
    52081 tcagctaacc aagaaataga ttctacttca aatcctttca aatcagctac taatcatcga
    52141 tcaacttcct taaagcgatc tactaaaaat gagaaactta caccaactgc tagtaatagc
    52201 caaaaaaacg gtagcaacaa gacaaaaatg ctagtggaca aagaggaagt aaaacctact
    52261 tcaaaaagag gattcccttg ggtcttatca ggtctagtag tcagtttagc tgcaggttta
    52321 tttatagcta ttcaaaaagt atctagacga aaataaaaga gtctatgcat ttattttgaa
    52381 gcattcatgg tataataaac tcatggaaga taaagatact attgaaacaa acgatatcgt
    52441 ctatggtgtt catgccgtta cagaaagcct tcaagcaaat acaggaaata agctttatat
    52501 ccaagaggat ttaagaggaa agaaagtgga taacatcaaa agcttagcga cacaaaaaaa
    52561 ggtcgctatt tcatggacgc ctaaaaaaac cttgtcacaa atgactgatg gagctgtgca
    52621 tcaaggtttt gttctgagag tatcagcttt tgcctatact gatgttgatg agatcctcga
    52681 aatagcagag caagaagcaa atcctttgat tcttatttta gatggtctga cagatcctca
    52741 taatttagga tcgattttac ggacagctga tgctacaaat gtatgtggag tgattattcc
    52801 taaacatcgt tctgttggtg tgactccagt ggtctcaaag acgtctacag gtgctgttga
    52861 acatattccg atagcgagag taactaacct tagtcaaact ctagataaat tgaaagcaag
    52921 aggattctgg atttttggca cagacatgaa tggaacaccg tctgattgct ggaacactaa
    52981 tggtaaactt gctttagtca ttggtaacga aggcaaaggc atctctacca atatcaaaaa
    53041 gcaagttgat gaaatgatta cgattcctat gaatggtcac gtacagagct taaatgctag
    53101 cgtagcggca gctattctca tgtatgaagt tttccgaaat aggcgctaaa ttatgaaaaa
    53161 acggatatta ttagtagatg ggtataatat gattgccttt tggcaatcaa cccgtcagtt
    53221 gtttaagata aatcagcttg atcaggcacg taacacactt ttaacaaaac ttaatcatta
    53281 tgcccatttt gagaatatta atattatttg tgtttttgat gcccaatatg taccggggtt
    53341 aaggcaacga tatgaccagt attatatctc agtggtattt acagaggaag acgaaacagc
    53401 agatagctac attgagcgca tggcagcaga gttaaatacg gctatacata tggtagaagt
    53461 agctacgagt gatttaaatg aacaatggac gattttttct caaggagctc ttcgtgtcac
    53521 tgcaagagaa ttagagcaaa gagttcatac tgtcaaagct gatttagata aaatgtctag
    53581 agatattgat ctcaaaacgc ctaaactgcg gccttttgac caaggacagc ttattcaatt
    53641 gaaggatttt atgtctcagt tagatcgata atgagaatta cgactcgcca agtgcgggtt
    53701 tttttgataa aataaaacaa taattatttg attatcaaac taaaaaactg gatgaggaga
    53761 agtaagaatg acctttacaa taatgacaga ttcaaccgct gatttgaatc aaacctgggc
    53821 agaagatcat gatattgtcc ttataggatt aacgattttg tgcgatggag aggtttatga
    53881 aacggtcggt cctaaccgta ttagtagtga ttaccttttg aaaaagatga aagctggcag
    53941 tcatcctcaa accagtcaga ttaatgtggg agagtttgag aaggtttttc gtgaacatgc
    54001 taggaacaac aaagcactgc tttatcttgc tttttcttcg gttttatcgg gtacctatca
    54061 aagcgctcta atggcacgcg atcttgttcg agaagattat cccgatgcag tgattgaaat
    54121 tgttgatacc ttggctgctg caggaggaga aggctatcta accattttag cagcagaagc
    54181 cagagatagt ggcaaaaatt tactggagac taaagatatt gttgaagcag tgattcctcg
    54241 actgcgcacc tatttcttag tagatgatct ttttcatttg atgcgtggtg ggcgtctgtc
    54301 aaaaggttca gcttttctag gcagtttagc cagtatcaaa cctcttttgt ggattgatga
    54361 ggaagggaaa ttggtgccca ttgcaaaaat tcggggacgc caaaaagcca tcaaagaaat
    54421 ggtggctcaa gtggaaaaag atattgcgga ttcgacggtt attgtctctt atacaagcga
    54481 tcagggtagt gccgaaaagt tacgagaaga gctgctggcg catgagaata ttagcgatgt
    54541 tcttatgatg ccactaggac cagttatctc agctcacgtt ggtcctaaca ccctggcagt
    54601 ttttgtgatt gggcagaatt ctcgttaatc ccttataagg attgaagaga aatcctcaat
    54661 ccttttttgc tgcttaaatc aatcaagaat gtaaaatata tttgacaaaa tatccaaaat
    54721 aatttatatt atgtcatata aagatttaaa ggagaaacga atcatgtttg atagcaaaca
    54781 aaatctcgct aagtcacaat ggggtttcat tgtcataaca gcagtgatgg atctagttgt
    54841 gatagtagca acattactgg ctaagaccag ttttcaacgt tacttagttg gaggcgtagc
    54901 ggttatattg actagctttc tcatattgtt ggtatggggg ctaaagacag cgaaaaagct
    54961 ccaaacgaga ctagatagca aagaagtact agattctaag gtaagggacg atcagaagct
    55021 gcccagatat gacgaacgcc aaaaacagat tcttctcaaa ggatacacta ttgggttttg
    55081 gtttatgatt gtggctgttt ggctgtcaat ctttcttcat cgcttctcag agagactggt
    55141 atctgcaagc ttcctcttta cattggctct ttggggaggg ttggcagttc aaacgacata
    55201 ttgtaacctc aacggggtat cgccatttgt ggataggcgc tttggaaaac aaggcatact
    55261 ggtggggatg atagcaacag gaatgagttt aatcactata ggtttggcgg taagagagat
    55321 gatggcaggg caacttaaaa tgggaagctt tttcaaggct ggcggcagtg gatctttaat
    55381 ggtgttgggc ataacgctcc ttagtatggg agctagtatt ttctatcgtc attatctgga
    55441 tgctaaagag gcagatgaat gaagaacctc aaattaaaag cagcgcgtgc aggcaaagat
    55501 ttgtctcaac aagctctagc agatttggta ggcgtctcca gacaaaccat tgcggctgtt
    55561 gaaaaaggtg attacaaccc aacgattaat ctttgcattg ccatttgtcg agtacttgat
    55621 aagaccttag atgacctttt ttgggaggtt gatgattccc attaacatca gcagagcagc
    55681 tctgccattc ctcaaaaacg aaagaaaaaa taatccaata aaatcagcta aagcacttga
    55741 ctggagcctc ttaagtttga tatcatagta ggcggtattg tttaccccat ttgaaaggcc
    55801 ccggaacctt ccaaatacct tcgatgggat ggaacaccca tcaccttgta aacaaatatt
    55861 acgaattcgt ataggagaaa tcatgaacaa aacaactttc atggctaaac caggccaagt
    55921 tgaacgcaaa tggtacgttg ttgacgcaac tgatgtgcca cttggacgtc tttctgcagt
    55981 agttgctagc gtacttcgcg gaaaaaacaa accaactttc acaccacata ctgatacagg
    56041 tgattttgtt atcgttatca acgctgaaaa agttaaatta actggtaaaa aagcgactga
    56101 taaagtttat tacactcact caatgtaccc aggtggtttg aaatcaatca ctgctggtga
    56161 acttcgctct aaaaacgcag ttcgcttgat tgaaaaatca gttaaaggca tgcttccaca
    56221 taacactctt ggacgtgcac aaggtatgaa attgaaagtc ttcgttggcg gtgagcacac
    56281 tcacgcagca caacaaccag aagtacttga catctcagga cttatctaag aggaaaggag
    56341 cattaaataa tggcacaagc acaatatgca ggtactggcc gtcgtaaaaa cgctgttgca
    56401 cgcgttcgtt tggttccagg tactggtaaa atcactgtta acaaaaaaga tgtagaagaa
    56461 tacatcccac atgctgacct acgtttgatc attaaccaac cttttgcagt tacatcaact
    56521 gaaggttcat acgacgtttt cgttaacgtt gttggtggtg gttacggtgg acaatcaggt
    56581 gcgatccgtc atggtatcgc tcgtgcgctt cttcaagtag acccagactt ccgcgattcg
    56641 ttgaaacgcg ctggccttct tacacgtgac gcacgtatgg ttgaacgtaa aaaaccaggt
    56701 cttaagaaag ctcgtaaagc ttcacaattc tcaaaacgtt aagaacagct ttacatcaac
    56761 gattacaagc attttgcaag tctcttgcaa ggtgcttttt ttgtcgtttt ttgcttttga
    56821 tacctttttt tgataccgtt tcggaaaact tttgacttgg tttaatacgt ttatttagtt
    56881 atttttgaga tagttagcaa attgtttgat tgatttgtct tctccgactg cagtagcatg
    56941 actgtatgta tcaagagtta tttgactact agcatgtcct aaccttttgg ctgtatttac
    57001 tgggtcaact ccaatctcaa tcatcagggt tgcatgggta tgcctgaagc cgtgaggact
    57061 tattttttaa gactatgttg cttaatgacc tttgataaga tattgttaat atagtctgta
    57121 tgaagtggtt caatactccc ttctctagta cagtatgtaa atataaagtc agactcaatt
    57181 gaaagaggtg caactgctag ttgtgccttt tctttttggc tgatggcttt ccattcttgc
    57241 agaatagaaa tagtttcgct gtctagctta atctttctta ctgagaaatc atttttagtg
    57301 cttttttcga ttgcctgtcc gtctaatcgt cctaggctct tattgacgct tagtgtctca
    57361 ctctgaaagt ctatattagc ccatttaaga gcgcatagct cgcctttcct taaggccgct
    57421 ataagctagt agccgaaata gtgcgtagtg cttgtaaggc tctttctgaa gtactatggc
    57481 taaaaactcc tgaagttctt gaaccgtcca atagttttct attcgtgtct ttttccgctt
    57541 tggcataatg atttcagcca tagggttatg cttgagcagt ttcatcttga tggcaaaatc
    57601 aaagatcttt tcagtgtagg acttgatttg cttgatattc ttaaaggtct ttgctttatc
    57661 ggtgatgaag ttctggcagt ctaaagggga ggttttgtta atgggcaatt ctcccatgac
    57721 tggcaaaatg tgaagttgaa acagatcaag agtacgagaa gccgtggttg gctctaccgt
    57781 atcttgatag gcttgatacc attcctcgaa tatctcgcta taagttttat gagttggctt
    57841 ggtgaactcc tctaagtttc ctgaagcctt aaggtagatt agcctatctt cgtagtcttt
    57901 ggcttctttg tggaatatct actaaacagc ccgaacttat tttgctccta gttaattggt
    57961 aatctaccaa aaaagcccta gcaagactgc taaggctttt aatgtgttat ttgaataact
    58021 ttatatagtc gctttgagta ggaagcaagt aatcaataac gaccctattt tcttccccct
    58081 cgatatggta taggacaata taatctttac ttaaggtata acctttagtg ctgtgataat
    58141 ggatgatttt tgaaccatat ttttcatcgg catcaaaacc aacttctcgg aaaacctcga
    58201 gtttttctat gtcgctaatg atttgctcca ttttacgctg acctgatgtt gaggaatagt
    58261 tttgagaaat ataatcacga atttctttta gcttctctaa aacatcagga gcatagataa
    58321 tctgatattt cttatagtcc aagttcagcc ctcacttctt cagaggtata aaacttccct
    58381 tgacgaacat cctcaatatt tttgttgatt tcagcttgaa attgcttgaa aagtttttct
    58441 ttctctaact cctcttccgt caataagtca acctcgtttg tgacaacgac attttgtagg
    58501 aataatctta aagcagatga taaggttaaa ttttttttgt ttaatactgt cattgcttcg
    58561 cttaccaatt ctttattagc ttgaaaggta accgctctgt tttttttact gtagtcattt
    58621 tatgtaaccc ctttatgtaa tttatttaat tatatcatat atacaaaaaa gtcaataaaa
    58681 aagactcggt aattgagaca gattttcatt atttgataag ctccgaaact
//
LOCUS       DATWVB010000009        57784 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.009, whole genome shotgun sequence.
ACCESSION   DATWVB010000009 DATWVB010000000
VERSION     DATWVB010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57784
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.009"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            259..420
                     /gene="sagA"
                     /locus_tag="VCX65_000590"
     CDS             259..420
                     /gene="sagA"
                     /locus_tag="VCX65_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HEP5053070.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            642..1592
                     /gene="sagB"
                     /locus_tag="VCX65_000591"
     CDS             642..1592
                     /gene="sagB"
                     /locus_tag="VCX65_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HEP5053071.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYMKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            1589..2647
                     /locus_tag="VCX65_000592"
     CDS             1589..2647
                     /locus_tag="VCX65_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEP5053072.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENTLEPEMFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNAPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSEALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQILPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            2667..4025
                     /locus_tag="VCX65_000593"
     CDS             2667..4025
                     /locus_tag="VCX65_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEP5053073.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            4000..4671
                     /locus_tag="VCX65_000594"
     CDS             4000..4671
                     /locus_tag="VCX65_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEP5053074.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKGVT"
     gene            4668..5351
                     /locus_tag="VCX65_000595"
     CDS             4668..5351
                     /locus_tag="VCX65_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEP5053075.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLVALSYQDFLDV
                     LLSLFQFVIIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGIAILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            5374..6297
                     /locus_tag="VCX65_000596"
     CDS             5374..6297
                     /locus_tag="VCX65_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053076.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            6306..7433
                     /locus_tag="VCX65_000597"
     CDS             6306..7433
                     /locus_tag="VCX65_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053077.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIHLTG
                     VSPSLLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT"
     gene            7430..8548
                     /locus_tag="VCX65_000598"
     CDS             7430..8548
                     /locus_tag="VCX65_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053078.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSGQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGGTLSQAWPYLLALMGTALALISFSSLLLKPTKL"
     gene            9120..11852
                     /locus_tag="VCX65_000599"
     CDS             9120..11852
                     /locus_tag="VCX65_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
                     /protein_id="HEP5053079.1"
                     /translation="MINKKYIIPVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKSNFPVISPYLASVDFGERKTSLPTPDKGVKVTTEQSIAQVRKGPEERTYTV
                     TGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETTTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVIKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPCLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGRVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVNRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      12017..12132
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            12130..12630
                     /locus_tag="VCX65_000600"
     CDS             12130..12630
                     /locus_tag="VCX65_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEP5053080.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            12824..14782
                     /gene="ligA"
                     /locus_tag="VCX65_000601"
     CDS             12824..14782
                     /gene="ligA"
                     /locus_tag="VCX65_000601"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEP5053081.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTAVVAKRQLATFLYQE
                     ASPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWNFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRQL"
     gene            14796..15818
                     /locus_tag="VCX65_000602"
     CDS             14796..15818
                     /locus_tag="VCX65_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEP5053082.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDDALVLDQDELEIEEIVKKFAHEVEDL
                     EQELEE"
     gene            16210..16407
                     /locus_tag="VCX65_000603"
     CDS             16210..16407
                     /locus_tag="VCX65_000603"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEP5053083.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            16442..17158
                     /gene="atpB"
                     /locus_tag="VCX65_000604"
     CDS             16442..17158
                     /gene="atpB"
                     /locus_tag="VCX65_000604"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEP5053084.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            17176..17670
                     /gene="atpF"
                     /locus_tag="VCX65_000605"
     CDS             17176..17670
                     /gene="atpF"
                     /locus_tag="VCX65_000605"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEP5053085.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            17670..18206
                     /locus_tag="VCX65_000606"
     CDS             17670..18206
                     /locus_tag="VCX65_000606"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEP5053086.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTN
                     LDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQTVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            18222..19730
                     /locus_tag="VCX65_000607"
     CDS             18222..19730
                     /locus_tag="VCX65_000607"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEP5053087.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            19746..20621
                     /locus_tag="VCX65_000608"
     CDS             19746..20621
                     /locus_tag="VCX65_000608"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEP5053088.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            20783..22189
                     /gene="atpD"
                     /locus_tag="VCX65_000609"
     CDS             20783..22189
                     /gene="atpD"
                     /locus_tag="VCX65_000609"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEP5053089.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDDLPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            22202..22618
                     /locus_tag="VCX65_000610"
     CDS             22202..22618
                     /locus_tag="VCX65_000610"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEP5053090.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            22884..23141
                     /locus_tag="VCX65_000611"
     CDS             22884..23141
                     /locus_tag="VCX65_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEP5053091.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFR"
     gene            23206..24477
                     /gene="murA"
                     /locus_tag="VCX65_000612"
     CDS             23206..24477
                     /gene="murA"
                     /locus_tag="VCX65_000612"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEP5053092.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTSLHGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            24481..24669
                     /locus_tag="VCX65_000613"
     CDS             24481..24669
                     /locus_tag="VCX65_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEP5053093.1"
                     /translation="MTNGLKYVLEQMLLLLVIAALACLFLAIGLMIGYSFMGDGHSPW
                     HILSMDKWAELVNKFTGK"
     gene            24705..25569
                     /locus_tag="VCX65_000614"
                     /pseudo
     CDS             24705..25569
                     /locus_tag="VCX65_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
     gene            25852..26895
                     /gene="pheS"
                     /locus_tag="VCX65_000615"
     CDS             25852..26895
                     /gene="pheS"
                     /locus_tag="VCX65_000615"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEP5053094.1"
                     /translation="MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGEERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            27105..29510
                     /locus_tag="VCX65_000616"
     CDS             27105..29510
                     /locus_tag="VCX65_000616"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEP5053095.1"
                     /translation="MLVSYKWLKELVDIDVTPAALAEKMSATSIEVEGIEVPADGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIEVAIASDN
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANS
                     QTVVLEVAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIQRIFDQLGFGLTGDETSFT
                     VAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKEDLPNELNHFAFAICGLVAQKDFQTQAQAVDFYHA
                     KGILDTLFANLNLKVQYVPTKDLASMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALPSDQTFAEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTKIKLFDVYEGVTIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQVGA
                     EVR"
     gene            29620..29997
                     /locus_tag="VCX65_000617"
     CDS             29620..29997
                     /locus_tag="VCX65_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HEP5053096.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTLAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVMVTITLEGLSHV"
     gene            29990..30376
                     /locus_tag="VCX65_000618"
     CDS             29990..30376
                     /locus_tag="VCX65_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HEP5053097.1"
                     /translation="MSDAGLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            30449..31525
                     /locus_tag="VCX65_000619"
     CDS             30449..31525
                     /locus_tag="VCX65_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053098.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSILLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GISNKTITTAVLMQTFFLSFLGSGLGLLGTWLTSLLLPTVVPFQSNWFLYLAIFVSMI
                     CFALLGTLFSVFNIIRIDPLKAIG"
     gene            31535..32203
                     /locus_tag="VCX65_000620"
     CDS             31535..32203
                     /locus_tag="VCX65_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053099.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGITGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLKYCDKVYRMQDGEL
                     RQER"
     gene            complement(32308..33225)
                     /locus_tag="VCX65_000621"
     CDS             complement(32308..33225)
                     /locus_tag="VCX65_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HEP5053100.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSSVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASARQGKSKAKANQLNVKLE
                     LQADYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEETYGRTVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
     gene            33376..36591
                     /gene="rexB"
                     /locus_tag="VCX65_000622"
     CDS             33376..36591
                     /gene="rexB"
                     /locus_tag="VCX65_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEP5053101.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVIVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLVDKLILFFKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVPTVINETFDDLSPYLKELISFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQE
                     KNFHLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMAQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            36552..40220
                     /gene="addA"
                     /locus_tag="VCX65_000623"
     CDS             36552..40220
                     /gene="addA"
                     /locus_tag="VCX65_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEP5053102.1"
                     /translation="MLFNINEKGEPLVISFAPFLSPEAIKHLQENERCSDQSQKRTAQ
                     QIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLGQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDY
                     GQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDITHFAIKILEENTDIRQFYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYSIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNIFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQD
                     ITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
                     QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKVKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALREIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKVDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            40360..41172
                     /locus_tag="VCX65_000624"
     CDS             40360..41172
                     /locus_tag="VCX65_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEP5053103.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHYERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLNGKKVAAQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLEAPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            41313..41489
                     /locus_tag="VCX65_000625"
     CDS             41313..41489
                     /locus_tag="VCX65_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEP5053104.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(41617..41979)
                     /gene="mscL"
                     /locus_tag="VCX65_000626"
     CDS             complement(41617..41979)
                     /gene="mscL"
                     /locus_tag="VCX65_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEP5053105.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            42109..43923
                     /gene="dnaG"
                     /locus_tag="VCX65_000627"
     CDS             42109..43923
                     /gene="dnaG"
                     /locus_tag="VCX65_000627"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEP5053106.1"
                     /translation="MGFLWGGDDLAIDKEMISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNIPPSQAVLASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFNLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADMEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKIADLLPNFDYFQVEQSVNALRIQDRQK
                     RQGQIAQAVSNLVTLPIPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     EILYQRLKQQGYITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            43932..45041
                     /gene="rpoD"
                     /locus_tag="VCX65_000628"
     CDS             43932..45041
                     /gene="rpoD"
                     /locus_tag="VCX65_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEP5053107.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            45277..45615
                     /locus_tag="VCX65_000629"
     CDS             45277..45615
                     /locus_tag="VCX65_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEP5053108.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            45753..46607
                     /gene="rfbD"
                     /locus_tag="VCX65_000630"
     CDS             45753..46607
                     /gene="rfbD"
                     /locus_tag="VCX65_000630"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEP5053109.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFAMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            46726..47880
                     /locus_tag="VCX65_000631"
     CDS             46726..47880
                     /locus_tag="VCX65_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEP5053110.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSKPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLTTADSKVRAYFQTFDIREKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEDNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWSK
                     QKGQLAELINQVDAGFDSDRLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            47870..48802
                     /locus_tag="VCX65_000632"
     CDS             47870..48802
                     /locus_tag="VCX65_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEP5053111.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAICHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLTPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            48805..49608
                     /locus_tag="VCX65_000633"
     CDS             48805..49608
                     /locus_tag="VCX65_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053112.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYVVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            49608..50813
                     /locus_tag="VCX65_000634"
     CDS             49608..50813
                     /locus_tag="VCX65_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053113.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            50838..51845
                     /locus_tag="VCX65_000635"
     CDS             50838..51845
                     /locus_tag="VCX65_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEP5053114.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTVYRMTTDSDSR
                     PTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKEMSELLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            51842..53587
                     /locus_tag="VCX65_000636"
     CDS             51842..53587
                     /locus_tag="VCX65_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEP5053115.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGPIW
                     EMGPYFENFEEKEAIDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDAKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSVFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLFVYI
                     AWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            53584..56058
                     /locus_tag="VCX65_000637"
     CDS             53584..56058
                     /locus_tag="VCX65_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEP5053116.1"
                     /translation="MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPV
                     NYYAHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVRAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKPSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTSDK
                     TVYNNILSLINPSESQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARL
                     LSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNG
                     TNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQND
                     LKNIQYDVTIGKGYLLKHKTFFKISR"
     gene            56237..56932
                     /locus_tag="VCX65_000638"
     CDS             56237..56932
                     /locus_tag="VCX65_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEP5053117.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            56934..57275
                     /locus_tag="VCX65_000639"
     CDS             56934..57275
                     /locus_tag="VCX65_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEP5053118.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            57268..>57784
                     /locus_tag="VCX65_000640"
     CDS             57268..>57784
                     /locus_tag="VCX65_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEP5053119.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVA"
BASE COUNT        18428 a         9652 c        11546 g        18158 t
ORIGIN      
        1 gtatattaga tcataattgt ttctatatta atcaattatt attttttttg tcatttttga
       61 taatattaaa aagaaagggt ttacatatta atcatttttt actataataa aagtgataag
      121 aactagatag ttgttgtgtt acaacagtac aattgagcta gccttgtcct tgttgtgtta
      181 actttatttt taaaataagg ttaaaaataa acgactcgcg ttcttatcag ttacttatta
      241 gataaggagg taaaccttat gttaaaattt acttcaaata ttttagctac tagtgtagct
      301 gaaacaactc aagttgctcc tggaggctgc tgttgctgct gtactacttg ttgcttctca
      361 attgctactg gaagtggtaa ttctcaaggt ggtagcggaa gttatacgcc aggtaaataa
      421 tctatttagc atctctatgt gatagtgata ttaaggtaat gagtttgcta gcaactaagt
      481 tatctttggt aacttctgat tatagatgaa tggcatagag gtgttagaaa acatgagaca
      541 aaagtaatct tcttgatgct aacgtctcag gtaattagca ggtactagat agtacctgct
      601 aattactata tgtttagtaa aatgagatag gaaagatagt tatgtcattt tttacaaagg
      661 aacaacaacc taaagagaat tgtccgccaa taactgttga aaaagcaagg caattgtttg
      721 aatttaatac aaaccacttg tccttatcgg attaccatca tcaaacggtg ctaaaaacgt
      781 caaagcagct agttgctcaa catttaatgc ctaatgcaac cgataatctt agtcaacatt
      841 ttttgatgaa ctataaagct aataataatt atttaggctt ccaagctagt attgtcgact
      901 tttttacaga ttctgccgtt gctaattttt caagtagtta cgtttatgaa agtcaggaaa
      961 agataattcg tttaccaaaa cctaccaaga tatcaactgc tctgtcgaca tgtattataa
     1021 aacgaagaag tcatcgtcaa ttttcagata gacaaatgcc tcttcaagat ttatcaaaca
     1081 ttctttatta tgcatgtggt gttagttcac aagcatcaat tagagatgga gcatcagata
     1141 agattacact cagaaactgt gcttcaggtg gaggtttata ccctattcat ttagtttttt
     1201 atgctagaaa catcagtaaa ttaatagatg gtttctatga atatctaccc tatcagcatg
     1261 cactaaggtg ttatcggcat agctctgagg aaaacgttag agattttgcg gaatacggtg
     1321 ctattaatgc tgaaaattgt aatattatta ttatttatgt ctaccattac atgaaaaata
     1381 cacgtaaata tgggaatcag gcgactgcct atgcttttat tgaatcagga gaaatagccc
     1441 agaatattca attgactgca actgccttaa cttatggaag tattgatatt ggtggttata
     1501 ataaggaata tctccaagaa ttattagatt tagatgggct aggagagcat gtgattcaca
     1561 tgacactcgt aggaactaag gagtctcaat gaaatatcaa cttaatagta atgttcgtgt
     1621 cgtgacattt caagatacat tttgttttag aaaaggaatc tgggatttta atgaagccat
     1681 tctagatttg acacaagaac ctcaaaattt aaagatagtt tatcaagaaa tagtttcaca
     1741 gttggttaag ggagtagcca ttgatactga aacttatgaa aatactttag aacctgagat
     1801 gttcgctaat ttaatggaag tcatttcagg cttgtattac aatgatatgc tgatgcttga
     1861 ggatgactac aatcttgaag aaaatgtcat gaaaatttta atgggtaatt tccgttttat
     1921 ggcgcaagca ggtcatatgg taagcaatgc tcctgttttg tttatcagtg attcgactta
     1981 tgttaatgaa tctgctgagt tgctagctga acaactgcat ttacaattgc aagtggctag
     2041 cgatgactta aaaatgttaa ttcagcagac agatgttagt tcgcgtttag atgctttgga
     2101 gcatcgccgt aacatgaatt gtttatcaga agccttgtgc gattaccaaa gtattattat
     2161 ttgtcaagaa cgcttgaata ttatgatgtt gcgacacttg aatgaagtta gcgtagctat
     2221 gaaaaaacaa ttagtgattg gttttgtaga tggaccattc ttgcacactt gtactttgaa
     2281 tcctcctcat agtgctgact ttgatagctt agaaagaaga gttttggcac gtttacaaga
     2341 ctcaactctc tatcaacatt ttgctaatca gattttacca gcaacacaag atgtgagcca
     2401 ggcctattta ccattgttaa atgttttaat gaatttagtc gttagcgaag ctttcattat
     2461 tgctcaaaca ggtagttcta aatttgaggg acgtttatta agcatttact taccgacgct
     2521 tgagattcag gtccaagata ttttgaaaat gtctaattca cagacacaag gagctttggc
     2581 aaaattaaaa tatgaggatc agcagatatc aacacgtgag attgttaaaa aactccttga
     2641 cgagtaacct ataaggagaa tctattatgt tatactatta tccttctttt aatcatattt
     2701 ttgatgaatt aaaaagttta agtggcaatc gaacaggtat cttaaatcaa tctcaagttc
     2761 cagtttgcaa ccatcctcac gatgtttact taaaaagtat tactggccaa atgccagatt
     2821 atcataaaca atttataggt gagttgagtc aagttagtta tcacattatt ggttacggca
     2881 gttactatga agaagcactt atcaagtatt taggagaaag tattgaacgc tatgctactg
     2941 taattgccgg agacttacta tcagatcgga ttgtctatgc ttcttataat gagttaaaac
     3001 tgttacataa agtgatgcct ttagaatact tgcaagtgtt tactcaagaa cagatcgcat
     3061 tatcttgtga cttgcaaatg atgatgtgcg ataaaatggt aactgagaac gatgtattgg
     3121 gctgggttaa atgtcccatg ttctttgagg acgcagagat gtatgttcca gctcaaatgc
     3181 tttgtgttgg gtataaaaca aatgagactg taggagaaag acggataata ccaggatttt
     3241 ctacgggaac agcttctcac aaaacgttag aagcggctat gtgcaacagt ttgattgaat
     3301 acatccagat cgattcaatg atgcttagct ggtatactaa gaagccttgc cccaagatta
     3361 ttgttgatga tcctgatatt gaagtgattt tagaagaagc tagactggga aaagacagtc
     3421 tatacgacat tattcctatt gatatgactg taggagaaga taatcctctt tatacgtttg
     3481 gaatcattct caaaaataaa tatgatgaag ggccttacct cttgtttgga gtgcaggctg
     3541 ggttagatcc taaacatgct ttgctaagag ggatcatgga agcttcagct attagctata
     3601 gttactacta taatctttta tatcaaaaag cttcccttgc aaatattgaa tgcgaagaac
     3661 ctttgttttt agatttagat agtaatgtct tctattatgc acatcccaag gaccaagacc
     3721 ataaatggaa ggcctttgaa cctttgattt caggagaagt tctgttaagt gatttggaag
     3781 atcattctgg taaagataaa aaagaagatt tgaagacttt attagcttat gctaagaaag
     3841 tcagtcctaa tgctgtcttt ttagatatta cacctcctga agctctagaa aaaggctggt
     3901 acgtcacgcg agttctgatg ccagaacttc ttgaaatgtg tataccagca tttccttttg
     3961 ctaatcatcc acgaatgaga cagtttggag gtgtaacaaa tgcctttgtc catccaatgc
     4021 cttaatcttt gttttttgtt ggtaactttt tgtccttcaa ttcctatgca agctattttt
     4081 ggaaaggaag atagtggtta tgcatttaat ttaattggtt ttctaagagc aactctgatt
     4141 tatgacattt tggctttggt aagtatttat gttttgtcac ctcaaataac cttgtctctt
     4201 gaaagtattg atagtaagac gttctttatg ggacttgtat tttgcgtctt gatagtactg
     4261 attgaactcg ttttcttaca tggtttacgt tgttggcaaa aaaagcaatg gcttcctgca
     4321 actttctcgt ttgtaggaac gacaaatgat tggtctaaga ttggctatcc tttattacta
     4381 gctttatttg aagagacgat ttatcgtttt ttgtggttta atatattagc ttttcaatgg
     4441 catttaccaa caattattgt tttaattgta actagttttt gctatgcttt aaatcactta
     4501 ttgatgggga aatccatttt ttatgctaag ttggtaacag gcatcattta tggtagtatt
     4561 tacatgctga ctagtcaatt gtggttggtt gtgataatgc atgtaggagg gaacttgcta
     4621 gttgagtgtc ttagccatct tcaaacaaaa aagaagaagg gggtgacatg atgctattgg
     4681 ttttgctgtc gtttttaggt ctaactactc tttggttgac cagttatcga agacgttgtt
     4741 tggctagatg gcatcttcaa tggttagtgg ccttatccta tcaagatttt ttagatgtct
     4801 tactgagtct gtttcaattt gtcattatta tacttgtttt attcttttac tcagctacta
     4861 ttaatctagg agaggttctg acctttttga cacaaactag ctggcattgg cagattcttt
     4921 gttatttagt gttgtatctt atggccatca tagagatgac gcttttagtt ttaattctta
     4981 tctttgatgt tttgctccag aaagatagtc gattgctctt taaaaaaata acttggctgc
     5041 cttttagaca agataaacca gtcttaagta tacttttact aggcatagct attctagtag
     5101 acagtctctt ttatttgggc ttgcttatat tattaggaga acagtcgcta acaagtttag
     5161 caacgcttat tttaggttat gggatagtca aggcttgtcg ctattcaggc tggttaaatg
     5221 tactattagc tttttgtctt ttcactatag ttggactatg ggcagttacg gcaactttat
     5281 tatatggttg gctagtaggt gcgatgatat taacggtgac ttatttgatg attagttgca
     5341 aagagtatta gcaatattaa aaaggagtga tatatgagtt ttgtacaatt aacaaatgtt
     5401 gtcaagtcct acaaaaacgg caagaaagct gtcaatgatg tttccttgtc tattgaagca
     5461 ggtaatattt atggtctgtt aggaccaaat ggtgctggta agtctacctt gattaatctt
     5521 atcttaggct tgatcccttt gagttccggt aaaattactg ttttagggca atcccaaaag
     5581 actattcgaa aaataagttc gcagataggt tatgttcctc aagacattgc tgtttatcca
     5641 gacctaactg cttatgaaaa tgtagaacta tttgggtcac tttatggctt aaagggagct
     5701 cagcttaaaa aacaagttct aaaaagttta gaatttgtgg ggctacactc ccaagctaag
     5761 cagtttccaa gtcaattctc aggaggaatg aagagacggt taaatatcgc ttgtgcgcta
     5821 gttcattcac ctaaattaat catttttgac gaaccgactg tagggattga tcctcaatca
     5881 cgtaatcata ttttagagtc gattcgtttg ctaaacaaag aaggtgccac agttatttat
     5941 acgacccatt acatggaaga agtagaggct ctttgtgatt atatttttat tatggatcat
     6001 ggtcaagtta ttgaagaagg acctaaattt gaactggaaa aacgttacgt tgcaaatcta
     6061 gcaaaccaga ttattgtaac tctaacagat tcacgtcatt tggaactggc agataagcct
     6121 gattggtctt tgatagaaga tggagaaaaa ctcatgttga agattgataa tagtgatatg
     6181 acatcagttg ttcatcagct cacacaggcc aatattactt ttagcgagat tagacataac
     6241 catttgaatt tagaagaaat tttcttacac ttaacaggta agaagttacg agattagagg
     6301 ttactatggt tttatttcat ttaatcaaaa aagaaagttt acagattttt agaaaccgaa
     6361 cagccttatt gatgatggtg atttttccaa ttttgatgat cgttatttta agttttgcct
     6421 ttaaatcaag ttttaatact gcgacaacag tccctaaatt gaccattcgt taccaattag
     6481 agggtgaaaa aacggattac cagaaaaatt ttcttgcttt tttaaaagtt ttaaaccaaa
     6541 aacttcattt agaggctaaa cctagtaatt ctcttgaaaa agatcgacaa agggtcagtg
     6601 aaggagcctt aacggctgtt ttagaagtga agaagaatca gaccattaag gttattacta
     6661 ataatattaa tcagcaaaat gcagatttga tcaatatgct agtaaaaaat tatgtagata
     6721 atgctaaaac ttatgactcg atagcagctc tttatcctca acaattaaat catatcagaa
     6781 agcgaagtgt ggactatgtt aaggtcagtt caatacagac aagtaaagga atgacatcag
     6841 ctgattatta tgctatttct atgtttacca tgattacttt ttatagtatg atgtctgcga
     6901 tgaaccttgt tttgtcagat cgtcaacaac ggattacaaa tcgtattcac ttaacaggag
     6961 tttctccaag tcttttggtc tttggaaaat taataggtgc tatgttagca acaactgttc
     7021 aattgagtct tttatacatt tttacaaggt ttgttttacg agttaattgg ggcactaatg
     7081 agtggatgct tattggtata acagcctcct tagtctatct ctctgtagct ataggtatcg
     7141 ggctaggcat aagcattaaa aatgaggctt ttttaacggt tgcatccaat actattattc
     7201 ctatattcgc ctttttagga ggcagttacg ttccattgac aacattacac agctctatta
     7261 ttaatcaatt gtcgaatata tctcctatta aatgggttaa tgatagtttg ttctatctta
     7321 tttttggtgg tcaatataat ccgattcctg taactttgat cgttaatatt agtatcggaa
     7381 caatttttat aatattggca ttgataggta tgagaaagca ggtgacgaca tgatttgttt
     7441 tataaaaact ctatttgtta agataaagcg caaaaaaaca agttatgtga cattcttttt
     7501 aatgcctatt ttaacgacac ttttggcttt atctttgagt ttttcaaata ataatcaggc
     7561 taaaattggg atattagata aagataatag tcagatatct aaacaattta ttgctcaact
     7621 aaagcaaaac aaaaagtacg acatttttac caaaatcaaa aaagagcata ttgatcacta
     7681 ccttcaagat aaatctctag aagcggtatt gactattgac aaaggattct cagataaagt
     7741 gttgcaagga aaatctcaaa aactcaatat acgttcgatt gctaatagcg aaattacaga
     7801 gtgggtaaag gcacagacca attatctatt ggaaaactat aatattatag gggatgtggc
     7861 tctaggtaac gaagatactt ttaatagaat tctccaaaaa aaccaacagt taaattatga
     7921 tgttaagcaa gtaactttga cagaccgatc acgtagcaaa gcagtatctt ccacaacgac
     7981 aggatttttg cttattctaa tgttaggtag tacgagcgtg atttacagtg gtattttggc
     8041 agataaatct ggtcagttat accatcgatt aatgttatcg aacttatctc gttttcgcta
     8101 tatgttgagt tacgtctgtg taggatttgt tgcttttacg attcaaattg tcattatgct
     8161 gagtttgtta aaagtattta atattagttt ttttgttccg acatcacttc ttttgattat
     8221 ttttttcctt tttagtttat tagcgatagg ctttggcctg ctgattggag ctatcacaca
     8281 aaattcccaa caaagtagcc agttagctaa tcttattgta atgccgactt caatgttggc
     8341 tggctgttta tggccattgt ctattacgcc ttcttatatg caagcaattg gtaagttatt
     8401 accacaaaat tgggttttat cagccatagc tatttttcaa agtggaggga ccttatctca
     8461 ggcttggcca tacttgttag ctctaatggg aacagcacta gctttgatta gtttttcaag
     8521 tttattatta aaacctacca aactataatt agtcttttgt taaaaaatac tttcctaatt
     8581 agctaactac caggtagccc ttttattggc ttatatgcaa taaaagggtt gctttttgct
     8641 tatattttct ctagtgcact tatcttttgt taaaagcgat tgcgatgtta ctgttgttac
     8701 tgtgtttttt agagagcata ttatcaaaag cgacctctct agaaagttcg tttttgttga
     8761 cagattagtt gtcaaagtat tttaaaaaaa cgttttcaat aaacataaaa actaatgtta
     8821 ttaaaaaaag ttgtgaaaac gtatttattt tatggaatgt ttttgttaca ataagcatgt
     8881 atcgaatgct ataaagctgt cttgttcgct atcagggatg cttgtgatgt tatgtcagat
     8941 caaacaaatc tttaattggg tgacttaaca gattaaaaga aaagatctaa tcgtgttact
     9001 tgatagtata attaatgcaa acagaaagtg tatcccaatt catagtctca ggtggaggtt
     9061 aatattcaaa aataaaatct tgttgttgtc ttaaactaat cacattaaaa ggagatatca
     9121 tgattaacaa gaaatatata atacctgttt cattgttgac actagctatt acgcttacta
     9181 gtgttgaaga agttacttca cgccaaaatt tgacttatgc caatgaaatc gtaacacaaa
     9241 ggccaaagag agaatctgtt attagtgata aatcgaattt tcccgtcata tcaccttacc
     9301 tagcaagtgt ggattttggt gagagaaaaa catctttgcc aacacctgat aaaggagtaa
     9361 aagtaactac tgaacagtct attgctcaag taagaaaggg gcctgaagaa agaacctata
     9421 ctgttactgg caagattacg agtgtgatca atggctgggg aggctatggc ttttatattc
     9481 aagatagtga aggtattgga ctttatgttt atcctcaaaa agatttagga tacagtaagg
     9541 gagatattgt tcaattaaca ggtacactta ctcgctttaa aggtgattta caactccaac
     9601 aggtgactgc acacaaaaag ttagagttat cttttccgac ttctgttaaa gaagcagtaa
     9661 tatcagaatt agaaacaaca acaccctcaa cattagttaa gttatctcac gtgacagttg
     9721 gagaattatc aactgatcaa tataacaaca catctttcct tgtaagggat gatagtggta
     9781 aaagtatagt tgttcatata gatcatcgta caggggttaa aggggctgat gttgttacta
     9841 aaataagtca gggtgatttg attaacctca cagccatatt gtctattgtt gatggtcagt
     9901 tacaattaag accgttttct cttgaacaat tggaagtggt taaaaaggtc acaagctcaa
     9961 atagtgatgc ttcatctcgt aatattgtga aaataggcga gattcaagga gctagtcata
    10021 cgtcgccact tctcaaaaaa gcggtcaccg tagaacaggt tgttgtcact tatttagacg
    10081 attccactca tttttatgtt caagatctta atggtgatgg tgatttagcg acttcagatg
    10141 gtattcgtgt ttttgctaaa aacgctaagg ttcaagtcgg cgatgttttg accatttcag
    10201 gtgaagtgga agaattcttt ggtcgtggtt atgaggaacg taagcagact gaccttacca
    10261 tcacccaaat tgtggctaaa gcagtgatca aaacagggac agctcaagtt ccatcaccgc
    10321 ttgttttagg gaaagatcgt atcgcgccag ccaatattat tgataatgat ggcttgcgtg
    10381 tgtttgatcc agaagaagac gctattgatt attgggaatc aatggaaggc atgttagtgg
    10441 cggttgatga tgctaaaatc cttggtccaa tgaaaaataa agaaatttat gtcttacctg
    10501 gctctagtac aagaccgtta aataattcag gtggagtatt acttccagct aattcttata
    10561 acacagatgt gattcctgtt cttttcaaaa aaggcaaaca aattattaaa gcaggagact
    10621 cttacaaagg aagattagct gggccagtat cttatagcta tggtaattac aaggtctttg
    10681 ttgatgacag caaaaacatg ccatgtttaa tggatggtca tctaaaacct gaaaaaacaa
    10741 acttgcaaaa agaccttagc aagttaagca ttgcttctta caatattgaa aacttctcag
    10801 ccaatccttc ttcaactaaa gatgagaagg tcaaacggat tgccgaatcc tttattcatg
    10861 atctgaatgc tccagacatt attggattaa ttgaagtcca agataataat gggccgactg
    10921 atgatgggac aacggatgcg acacaaagcg cgcaacgcct cattgatgct attaaaaaac
    10981 taggtggccc aacttatcgt tatgttgata ttgctccaga aaataatgtt gacggaggtc
    11041 aaccaggtgg taatattcga acaggattcc tttatcaacc agagcgcgtc agcctttctg
    11101 ataagccaaa aggcggtgct cgtgatgctc taacttgggt taatggagaa ttaaacctta
    11161 gtgttggtcg aattgatcca actaacgccg cttggaaaga tgttcgtaaa tcgctagcag
    11221 cagaatttat cttccaaggt cgtaaagtcg ttgttgttgc aaatcatttg aactctaagc
    11281 gtggggataa tgctctttat ggtcgtgtgc aaccagtcac ttttaaatct gagcaaagac
    11341 gtcacgtctt ggctaatatg ctagcacaat ttgcgaaaga aggggcaaaa caccaagcta
    11401 atattgtgat gctaggtgac tttaatgatt ttgaattcac aaagacgatt caattaatcg
    11461 aagaaggtga tatggttaac ttggtgaacc gacatgatat ttcagatcgg tattcttatt
    11521 ttcaccaagg caataatcag acccttgata atatattagt ttcacgccat ttacttgatc
    11581 actacgaatt tgacatggtt catgtgaatt ccccatttat ggaagctcac ggacgcgcat
    11641 cagatcatga tccattgtta cttcaattat cattttctaa agaaaatgat aaggcagagt
    11701 cttctaaaca aagtgtaaaa gctaaaaaaa cttcaaaagg aaaactgttg ccaaaaacag
    11761 gagatagtct tgtttatgtg ataacgctac taggaacggc tagtttatta gtgcctattt
    11821 tattattgac taaaggcaaa aaggaatcat agcgatttga agaattggag ttcataaaga
    11881 gtcgttaaag gcttgatata cttacgttag accttaagct aaaatggatg actatataaa
    11941 aactaatatt gataacaaaa gaagataaca ataagacagc tttacttgct aaagactttt
    12001 gtcaagctaa ttgttttatg gtacaatgta accgttgctt tgcaaccctt ggtgcttagt
    12061 tccctttcac caagcatatt agaaacgtag atagcttttg agagttatcc agacgttaaa
    12121 ggagaaaaaa tgacaaaatt gactgtacac gactatgttc acattgggct agtagctgcc
    12181 ttgtatgttg tcttaactat taccccgcct ttaaatgcga tttcttatgg gatgtatcaa
    12241 tttagaatat ctgaaatgat gaatttctta gctttttatc atcgcaagta tattattgcg
    12301 gtgactcttg gatgtatgat tgctaacttt tatagtttcg gactgattga tgtctttgta
    12361 ggcggcggtt caactcttat ttttgtgacc ttaggtgtta ttttgtttag taagtatcaa
    12421 aaagattatc tttttaatgg catttttaat aaagcttttg tttacttttc tttctttttt
    12481 gcaacttcca tgtttactgt agcaatcgaa ctttacttct ttggagctcc atttttatta
    12541 acatggttta caactgcgtt gggagaatta gtatctctgc tcataggatc acttattatt
    12601 gataagttgt ctcaaagaat ttccttttag taatgcatca tactcaaaag agttgggtca
    12661 atacccttct cttttttatg ttgtttgtaa tgttaaaatc gttctagata gaaatattta
    12721 acactttagc taatagtacc atatggagtg gccaacgatt acttttgatg ctgttatgat
    12781 atagaaatag ctcatttgtt atcttttatg ataaaataaa agtatgaaaa aacgcataaa
    12841 agaattaaca gatcttctta accgttaccg ttatgactat tatactaaag atgccccatc
    12901 agtttctgac agtgactatg ataagcttta tcgtgaactg gtgactttag agcagtcata
    12961 tcccgagtat gtcttgcaag atagcccaac gcagcaggtt ggagggacta ttttaaaggg
    13021 gtttgaaaaa tatcgacatc agtatccgct ttttagtttg caggatgctt tttcacgtga
    13081 ggagctggat gcttttgata agcgcgtcaa ggccgaattt ccgaatgcca cctatctagc
    13141 agagttaaaa attgatggtt tatctatttc cttgagttat gagaatggct tcttacaggt
    13201 tggagcaaca cggggtgatg gcaatatcgg tgaaaatatc acagaaaata ttaaaaaaat
    13261 aaaggatatt cctcaccaat tgagtgagcc tttaaccatc accgttcgag gagaggctta
    13321 catgtctcgt cagtccttta aagcgatcaa tgaagcacgc caagaaaatg gggagactga
    13381 atttgctaat cctagaaatg ctgccgctgg gacactaagg cagctagata cggcagtggt
    13441 tgctaagcgt caactagcca cttttttgta tcaagaagct agtccgacag ctagaaatca
    13501 acaaaatgag gtcttagcag aattagcaga tctaggtttt tcagtaaatc cgtattatca
    13561 actcacatcg tctatggatg agatttggaa ttttatcaaa actattgagg caaaaagaga
    13621 tcaattagct tatgacatag atggcgttgt tattaaagtt aatagcctag ccatgcaaga
    13681 agagctaggg tttacggtta aagctccacg ctgggctatt gcttacaaat ttccagcaga
    13741 agaaaaagag gcagaaatcc tttcggttga ctggacagtg ggacgaacag gcgtggtcac
    13801 acctacagcg aatctaactc ctgtgcaact agcggggaca accgtgagtc gtgcaaccct
    13861 acataatgtg gattatattg ccgaaaaaga tatccgtatt ggcgatacag tgattgtata
    13921 taaggcaggg gacattattc ctgctgtctt aaatgtcgtt atgagtaagc ggaaccagca
    13981 agaagtcatg cttattccta aactatgccc atcttgtggt agtgaattag ttcattttga
    14041 agatgaggtt gctttgcgtt gtattaatcc gttgtgtcct agtttgattc agcgaagttt
    14101 ggagcatttt gcaagtcgtg atgccatgaa cattactggg ctgggaccag ctattgtgga
    14161 aaaactattt ttagcggggt ttgttcatga tgttgctgat atttaccagt tgaccaaaga
    14221 agatttcatg caattagatg gcatcaaaga aaagtcagct gataaattgc tcgctgcgat
    14281 tgaggcttct aaatcaaatt cagctgaaaa actgttattt ggtctaggaa ttcgtcatat
    14341 tggctctaag gttagtcgct taattttaga ggtatacgga gatatttctg ctcttttaac
    14401 cgctaaagaa gaggaaatcg caaggataga tggtcttggc tcaacgattg ctcaatcact
    14461 tactcaatac tttgaacaaa aaacggctgc gattttagta gacgagttaa agacagcagg
    14521 tgtcaacatg cattactcag gtcaaaaagt taatagtgac gcagcgcttt ttggtctaac
    14581 tgttgtttta actggcaaat taaatcagct gaaccgaaat gaggccaaag ataaattaga
    14641 ggcattaggt gccaaagtta ctggaagtgt atctaagaaa acagatttag ttattgcagg
    14701 tagtgacgct ggttctaagc tagaaaaagc aaagagctta ggaattcgga ttgaagatga
    14761 agattggcta cgccagcttt aagtgaggta atgttatgaa aaaacaattg agagcacgtc
    14821 tcatttataa tccaacgtca ggacaagaac ttatgagaaa aagtgttcct gaagttttag
    14881 acatattaga agggttcggg tatgaaacat ctgcctttca aacaacagcc caaaagaact
    14941 ctgctctaaa tgaagcaaga agagcggcaa aggcaggttt tgacttattg attgctgctg
    15001 gaggtgatgg cactattaac gaagtggtca atggaattgc tcccttgaaa aagcgcccta
    15061 aaatggccat tattccaaca ggtaccacta atgattttgc tagagcgtta aaagtaccaa
    15121 gaggaaatcc gagccaagca gcaaaactta tcggaaaaaa tcagactatc cagatggata
    15181 ttggtagagc taagaaagat acttatttca tcaatattgc tgcagcagga agtttgacgg
    15241 aattaactta cagtgtacca agtcagttaa aaacgatgtt tggatacttg gcttatcttg
    15301 ctaaaggagt agaactgctc ccaagagtta gcaatgtgcc tgttaaaatt acgcatgaca
    15361 aaggcgtctt tgaaggtcaa gtttctatga tttttgcagc tattaccaat tctgttgggg
    15421 gatttgaaat gattgctcct gatgcaaaac tagatgacgg tatgtttacg ctcattttaa
    15481 taaagacagc aaatcttttt gaaattgtac atcttttgcg tttgattttg gatggtggta
    15541 agcatattac agatcgtcgt gtcgaataca ttaagaccag taaaatagtc attgaacccc
    15601 aatgtggtaa gcgaatgatg attaatttag atggcgagta cggaggagat gctccaatta
    15661 cattagagaa cctaaaaaat catatcactt tttttgcaga tactgatttg atttctgatg
    15721 acgctttagt cttagatcag gacgaattgg aaattgagga aatcgtaaag aaatttgctc
    15781 atgaagtaga agacttagaa caagaattag aagaataata caatagttat tagctactga
    15841 cagtttagtc aaatgcacta ctattagaat ctaagatttt taaattaatt gaggtagtgt
    15901 tttttgatgt gctcaaagag tcaatttatt catatgaggg gcccatttga ggtctctctt
    15961 ttttgatcat atgcaagaaa atgccatgtt ttagggatgt tattataccc tttttggaat
    16021 cttgttgcct ttttgttata ataagagtgt aattctattt ttaaaaagat cttaacaaag
    16081 acagactcgt ttatcaaaaa ggttagtatt agtctaagaa agcgtactca gtctaaagaa
    16141 atctgttgac attcttaatt ttaaggaata gaatagcaaa gtaaaaaaaa tttaaaggag
    16201 tattctacta tgaatcctat tttcgcattg gctttggcct gttttggtgt ttctcttgcc
    16261 gaaggtttct tgatggcaaa tctttttaaa gcagcatctc gccaaccaga aatcattggt
    16321 caattacgtt cattaatgat cttgggtgtt gcctttatcg aaggtacttt ctttgttacc
    16381 cttgttatgg ccttcattct taaataacag cctatttgat aatagaaaag gagggtgtta
    16441 gatggaagaa gctaaaatac ccatgctaaa gcttggtcca ataaccttta atttgaccct
    16501 acttgctgtt tgtattgtca caattgctgt tatctttgcc tttgtttttt gggcaagtcg
    16561 ccaaatgaaa ttgaaaccag aagggaagca aactgcttta gaatatttaa tcagttttgt
    16621 ggatggtatt ggagaagagc acttagatca taatctacaa aaatcttatt cgctgttact
    16681 ctttaccatt tttctctttg tggctgtcgc taataattta gggttattta ctaagttaga
    16741 gacagttaat ggctataacc tatggacctc gccaacagcc aatctggctt ttgaccttgc
    16801 tctatctctt tttattacct taatggtaca cattgaaggg gttagacgtc gtggcttggt
    16861 tgcccatttg aaacgtttgg ctacaccgtg gccaatgact ccgatgaatt tattagaaga
    16921 gttcacaaat ttcttatcac ttgccattag gttattcggt aatatctttg ccggggaagt
    16981 tgttacaggt ttgattgttc aactggccaa ttatcgagtt tattggtggc cgatcgcttt
    17041 cctagtcaat atggcgtgga cagccttttc agtctttatt tcctgcatac aggcttttgt
    17101 tttcacaaaa ctgacagcga cctatctagg aaagaaagtt aatgaatcag aagaataagg
    17161 aaggagaaca aacgaatgtc aatcacattt ggtgaactcg ttgggaattt tattctagta
    17221 acaggttctg taatcgtctt gttactcttg atcaaaaaat tcgcttgggg tgcaattgaa
    17281 tcgattttac agacacgctc acaacaaatc tctcgagata ttgatcaggc tgagcaatca
    17341 cgtttaagtg ctcaacagtt agaggcaaaa agtcaagcta acctagatgc tagtcgttca
    17401 caagcaagta aaatcattag tgatgccaaa gaaattggtc aattacaagg tgataaattg
    17461 gtggcagaag ctactgatga agcaaaacgc ttgaaagaaa aagcgttgac agatattgaa
    17521 caaagcaaat cagacgctat ttcagcagtc aaaacagaaa tgtctgattt aacggttctt
    17581 ttagcggaaa aaattatggg agccaatctt gataagacgg cgcaaagcca gcttattgac
    17641 agttatcttg atgacttagg agaagcttaa tgaccaaaaa agaacaggct cttatcgagc
    17701 aatatgcaaa aagccttgtt gaggtagcaa gtgaacatca ttctcttgat gccttacaag
    17761 ctgatgtgct tgcgatttta gagacgtttg taacaactaa tcttgatcaa agtctatcaa
    17821 gtctagctgt tccgcatgct gaaaaaataa aattgctaac cttattaaag ggaaataatt
    17881 ctgtttatat gaataatttc ttgaatctca ttttacaaaa cgaacgtgaa gcttatttgt
    17941 atcaaatgct tcagactgtt ttaaatgaaa ttgcaatagt ttcaaatcag tatgatgtga
    18001 ctgttacctc atcactacct ttgactgagg agcaaaaaag ccgtgttcga gcagttgttg
    18061 caaagaaatt tgctgtaaca gcgggtcgtt taattgaaaa agtagatcct tcgcttattg
    18121 gaggatttat tatcagcgtc aataataaag taattgatac cagtattcgt cgtcaattgc
    18181 aagcatttaa aatgaattta aaatagaaag tggtgtgact tttggcaatt aatgcacaag
    18241 aaattagcgc tttaattaaa aagcaaattg agaacttcca gccaaatttc gatgtcacag
    18301 aaactgggat cgttacctat attggtgacg gtattgcacg tgcccgtgga ttagataatg
    18361 ccatgagtgg tgaacttctt gaatttgaaa atggtgccta tgggatggct caaaaccttg
    18421 agtcaaatga tgtaggtatt attattcttg gtgatttttc agcaatccgt gaaggagatg
    18481 tggttaagcg caccggtaaa atcatggaag taccagttgg tgaagctctc attggacgtg
    18541 tggtaaaccc acttggacaa ccagttgatg gcttgggaga tattgaaaca actggcttta
    18601 gaccagtcga aacgccagct cctggtgtta tgcagcgtaa atccgtttct gaacccttac
    18661 aaactggatt aaaagcaatt gatgctttgg ttccaattgg tcgtgggcaa cgtgagttga
    18721 ttatcggaga ccgtcaaaca ggaaaaacat ccgtagctat tgatgcgatt ttgaaccaaa
    18781 aaggtcaaga catgatttgt atctatgtgg ctattggtca aaaagaatca accgttcgta
    18841 cacaagttga aacccttcgc cgttacggtg ccttggatta tactattgtt gtgacagcgt
    18901 cagcctcaca accatcacca ttgctcttca tcgctcctta tgcgggtgtt gccatggctg
    18961 aagaatttat gtaccaaggc aagcatgtct tgattgtcta tgatgattta tcaaaacaag
    19021 cggtggctta tcgtgaattg tctctcttgc ttcgtcgtcc accaggtcgt gaagcttacc
    19081 caggggatgt tttctacttg catagccgtc ttttggaacg ctctgcaaaa gtttctgatg
    19141 acttaggtgg aggttctatc acagctctac catttatcga aacacaggcc ggagatatct
    19201 ctgcatatat tgcgactaac gttatttcga ttacagacgg acaaatcttc ttgcaagaga
    19261 acctctttaa ttcaggaatt cgtccagcga ttgatgcagg atcatctgtc tcacgtgtag
    19321 gtggttcagc tcaaattaaa gcgatgaaaa aggttgctgg tactcttcgt ttggatttgg
    19381 cttcctatcg tgaattagaa gcctttaccc aatttggttc ggaccttgat gctgcaacac
    19441 aagcaaaact taatcgtggt cgccgtacgg ttgaaatctt gaagcaacca ttgcataaac
    19501 cgttacctgt tgaaaagcaa gtcgttattc tttatgccct tactcatggt ttcttagatg
    19561 atgttcctgt agatgatatt ttggcttttg aagaagctct ttacgactac tttgacgttc
    19621 attacaatga tttatttgaa actatccgta ccacaaaaga ccttcctgaa gaagctgccc
    19681 ttgatgccgc tattaaagcg tttaaagaac actcaaactt taagtcatag agggaggata
    19741 ctagtatggc aggctctcta agtgaaatta aagctaaaat tatttcaact gagaaaacaa
    19801 gtaaaatcac tagtgccatg cgtatggttt cttctgcaaa acttgttaaa tctgagcaag
    19861 cagctcgtga ttttcaaatt tacgcctcaa aaattcgcca gattactaca gatttattga
    19921 aatcagaatt aaccatagga tctgataatc cgatgttggt gtctcgtcct gtcaaaaaaa
    19981 caggctatat tgtcatcacg tctgataaag gacttgttgg aggttacaat tcaaaaatct
    20041 tgaaatctgt tatggatatg attacagagt accatgctga tggtgactat gaaatcattt
    20101 ctattggtag tgttggttca gacttcttca aagcaagagg gatgaatgtg gcttttgaac
    20161 ttcgtggact tgcggatcaa ccaagttttg aacaagtgag acaaatcatt tcacaatccg
    20221 ttgacatgtt tgtcaatgag atttttgatg agttatatgt ctgttacaat caccatgtga
    20281 atagcttaac cagccaagtc cgtgttcaac agatgttgcc aatttctgac ttggttgctg
    20341 atgaagcagc agaagaaggt gttactgggt ttgaattgga acctaatcgt catgatattt
    20401 tagatcaatt gttacctcaa ttcacagaaa gtttaattta tggggctatc attgatgcta
    20461 aaacggctga acatgcagca ggtatgactg ccatgcagac agcgacagat aacgctaaga
    20521 atgtcattaa cgatttgacc atccaatata accgagctcg tcaagcagca attacacaag
    20581 aaattactga aattgttgca ggagcaaatg cactagaata aaaaataacg ctgactagcg
    20641 attaggttat tgtcagcatt caattttatc aatcgagatg aaatgactta tgggactttt
    20701 ctattgaaag actgctcttt tcagtataaa agaagttagc aagactaact aagccctgac
    20761 tatcgaatat aaggagaaat gaatgagctc aggcaaaatt gctcaggttg ttggtccagt
    20821 agtagacgtt atgtttgcga gtggggacaa acttccagag attaataatg cattgattgt
    20881 ttataaagat agtgataaaa agcaaaaaat cgtccttgaa gttgctctgg aacttggtga
    20941 cggtatggtg cgaacaatcg ctatggaatc aactgatggg cttacacgtg ggttagaagt
    21001 tcttgacact ggtcgtgcga ttagcgtacc agtaggtaaa gaaactttgg gacgcgtctt
    21061 taatgtactt ggagaaacca ttgatttgga agaaccattt gcagaagatg ttgaccgtca
    21121 gccgatccat aaaaaagcac catcgtttga tgaattatca acatcatcag aaattcttga
    21181 aactggtatc aaggtaattg accttcttgc cccttacctt aaaggtggta aagttggact
    21241 tttcggtggt gccggagttg gtaagactgt ccttatccaa gaattaatcc acaatatcgc
    21301 ccaagaacac ggaggtattt cagtatttac cggtgttggt gagcgaacac gtgaaggaaa
    21361 tgacctttac tgggaaatga aagaatcagg cgttattgaa aaaaccgcca tggtttttgg
    21421 tcagatgaat gagccgcctg gggcacgtat gcgtgtagcc cttactggtt taaccattgc
    21481 tgagtatttc cgtgatgtag aaggccaaga tgttttgctc tttattgata atatcttccg
    21541 tttcactcag gcaggttcag aagtatcagc cctcttaggc cgtatgcctt ctgctgttgg
    21601 ttaccaacca acacttgcta ctgaaatggg gcaattgcaa gaacggatta catcaactca
    21661 aaaaggttct gttacatcta tccaagcgat ttatgtacca gcagatgatt atactgaccc
    21721 tgcgccagca acagcatttg ctcacctgga ttcaacaact aaccttgaac gtaaattgac
    21781 acaaatgggg atttatccag ccgttgatcc attggcttca agttcacggg ctttatcacc
    21841 tgagattgtt ggtgaagagc actatgctgt ggcaacagaa gttcaacgtg tgcttcaacg
    21901 ctaccgtgaa ttacaagaca tcatcgctat tttggggatg gatgaattat cagatgaaga
    21961 aaaaacattg gttggacgtg cgcgtcgtat ccagttcttc ctctcacaaa attttaacgt
    22021 tgctgaacaa tttaccggtc ttcctggttc ttacgtgcca gttgctgaga cagttcgcgg
    22081 ctttaaagaa attcttgaag gaaaatacga tgatcttcca gaagacgcct ttcgttcagt
    22141 tggtccaatc gaggatgtga ttaaaaaagc cgaaaaaatg ggcttttagt gaggtgatgc
    22201 catgacacaa atgactgttc aagtggtaac gccagatgga atcaaatatg atcaccatgc
    22261 taaatgtatt tcggtaacaa caccagatgg ggaaatgggg attttaccta atcacatcaa
    22321 tttaattgca cctttgcaag tccatgaaat gaaaattcgc cgaggtggtg aagatgaaaa
    22381 agtggactgg attgctatca atggtggtat tattgaaatc aaagataatg tggttaccgt
    22441 tgtcgctgat tctgcagaac gtgaccgtga tatcgatgtc agccgagcag agcgagcaaa
    22501 actaagagca gaacgtgaaa ttgcacaggc tgaaacgact cacaacattg atgaagttcg
    22561 tcgtgccaag gttgccttgc gccgcgcttt gaatcgtatc aacgttagta aaaagtaagt
    22621 ggtgttgata aaagacaagg ataagtaaga aaggttttta acctattatt ttgtttgctg
    22681 agtcttttta acatcagttt ctgagagttt gaccatacta ccttctctaa acacgttatt
    22741 attgttgaga ggagttatat gggggaactc ttttttgtat ccacgttgtt agtagaaact
    22801 cagtaatgac gcttaatgta tttttaggct atcaacttag tcagagaaga tgtcaactta
    22861 attgataagt tggacggatc aagatggtat gttataataa tcctatggaa ttattaatga
    22921 agatcattgc cttttcgtgt catttatttt ttattggcct tagttaccaa ttactgatta
    22981 gtgtgattga ctggacaaaa tttagtcatt atcatccaga aaatcttggc cggctacgac
    23041 tttttgtctt tttattagct actgccctag ggtatttggt gagccattgt atgctggaat
    23101 tgcttcaaat tagccagacg ctcttttttg agttccgcta atactggaat aaaagaagta
    23161 tggtataatt ttactacgac taagagatag ataagggaga aaattgtgga taaaataatc
    23221 attgaaggtg gtcaaacacg cttagaagga gaagttgtta ttgagggtgc taaaaacgca
    23281 gttcttcctt tactggcagc atctatttta ccttcaaaag gaaaaacaat tcttagaaat
    23341 gttcctattc tatctgatgt ttttaccatg aataacgtgg tacgtggttt agatattcgt
    23401 gttgatttta atgaagcagc taacgaaatc acagttgatg cctcaggaca cattttagat
    23461 gaagcccctt acgagtacgt gagccaaatg cgtgcctcta ttgttgtttt aggaccaatt
    23521 ttggcacgta atggccacgc aaaagtatca atgcctggag gctgtacgat tggcagtagg
    23581 cctattaatt tgcacttaaa aggattagag gctatggggg caacgattac tcaaaaaggt
    23641 ggagatatta ccgctcaagc agatcgactg caaggtgcca tgatttatat ggacttccca
    23701 tctgtaggag ctacccaaaa cttgatgatg gctgccactt tagctgatgg tgtgaccact
    23761 attgaaaatg ctgctcgtga gcctgaaatt gttgatttag ctcaattttt gaataaaatg
    23821 ggagctagaa ttcgtggtgc tggaacagag acgttaacga taacaggcgt cacaagtctt
    23881 catggggtgg agcacgatgt ggttcaagac cgtattgaag caggtacttt tatggttgca
    23941 gcggcgatga cttcaggcaa tgttttgatt agagatgctg tttgggaaca taatcgtcca
    24001 ttgatttcaa aattaatgga aatgggtgtt tctgtaacag aagaagaata tggtattcgc
    24061 gttcaagcaa acacgccaaa gctcaaacct gtaacggtta aaaccttgcc tcatccaggt
    24121 tttccaacag acatgcaagc tcaatttaca gctttaatgg cagtggtcaa tggggagtct
    24181 actatggttg aaactgtctt tgaaaatcga tttcaacatc tggaagaaat gcgacgcatg
    24241 ggcttacaat ctgaaatcct tagggaaact gccatgattc atggtggaag acaactgcaa
    24301 ggtgctcctg tgatgtcaac agatttacgt gccagtgctg cccttatctt gacagggatt
    24361 gttgctcaag gagtgacaat agttaataat ttggttcatt tagatcgtgg ctactatcaa
    24421 tttcatgaaa aattagcaaa gcttggagct actattagtc gtagcagtga ggtctagctt
    24481 atgacaaatg gtttaaaata tgtcttagaa caaatgttat tacttttagt aattgctgcc
    24541 ttggcgtgtc tttttttagc cattggactt atgattggtt atagttttat gggagatggc
    24601 catagtccat ggcatatttt atctatggat aagtgggcag agttagtgaa taaatttact
    24661 ggaaagtagg ccttgcctac tttttatagc atttgagagg aagtatgtta acaaggaaaa
    24721 aacgaaaaag gatgcttaat tccttcttat tgattttgtt agtgttgggg tctaacagcc
    24781 ttgctaagag tgatttcata gctagcactc accctatcaa gcaactttat cagactcttg
    24841 ttggggagaa gaaaaaatca ttactcacac ataataattt gcccgctgat gttcccacag
    24901 aagctctggc ggcatcggta ttgacaccat caatcaaaaa gcaactaggt ccagatgttc
    24961 agtggaatgg agcaggcgcc tatattatca acaggaacaa aacagattta actgctaagg
    25021 tagccagtcc gccttatgcc aacaatgaaa ccaaatgggt gcaagagcaa aaggttccta
    25081 ctagagctaa tgccttactt actaagtcga cacgacagta tcaaaatcgc tatcaaacga
    25141 acaatgctta tcgtaccttt aagccagcag gttggcaccg attgcaccac ttaaaaggaa
    25201 gttatgatca cgcggttgat agagggcatt tgctaggtta tgctttagtt ggtggactga
    25261 aaggttttga tgcttaccag taatcctgat aatattgcca ctcaactaag ttgggctaat
    25321 caagtaaata aaccctactc gacaggtcag aactactatg aaggtttagt acgtcgtgct
    25381 ttggataagg ggcatcgcgt ccgctaccgt gtcaccctac tttatgatgg tgataatcta
    25441 ctagccagcg gtagccattt ggaggctaaa tcctctgatg acagcttgac ttttaacgtg
    25501 tttgttccaa atgtccaacc aggattgacc gttgactatc ggacgggaca aatagctatc
    25561 aatctctaag cgaaaagtca ctgatttaag attgtcacta agcacttttt ttgatagaat
    25621 agaactaatt gaataagtgt ctatgagact agtactaata gagaaattaa cagggagtga
    25681 gggccgtgac tggaagcctt cttaagggaa ctattaggaa ttcactcagc taaagacaat
    25741 taattaaggt ctgataacat cagataaaaa cggatggtac cgcgtgtcaa cgctccgctt
    25801 atgaagtgga gtagtggcac gcttttttca tcgctaaaag aagggaaaac tatggattta
    25861 caagcacaat tagaggaatt aaaaacaaaa acattggaga ctctccaatc tttgacgggg
    25921 aatcatacca aagaactgca agatttgcgc gtggctgttc ttgggaaaaa gggatctttg
    25981 acagaattac taaaggggct aaaagacttg tctaatgact tgcgtcctgt ggttggtaaa
    26041 caggtgaacg aagttcgtga cttattgaca aaagcctttg aagaacaggc taaaattgta
    26101 gaagctgcta aaattcaagc ccagcttgat gctgaaagca ttgatgtgac tttaccgggt
    26161 cgtcaaatga ctctgggcca ccgtcatgtg ttaacacaaa ccagtgaaga aatcgaagat
    26221 attttcttag gaatgggttt tcagattgtt gatggctttg aggtagaaaa agattattac
    26281 aactttgagc gcatgaattt gccaaaggat caccctgccc gtgacatgca agatacgttt
    26341 tatatcacag aagaaatctt gttacgaact cacaccagtc ctgtgcaggc ccgtactctt
    26401 gatcaacatg atttttcaaa agggccttta aaaatggttt ctccaggtcg tgttttccgt
    26461 cgtgatactg atgacgctac ccactcacat caattccatc aaattgaagg tttggttgtg
    26521 ggcaaaaata tttccatggg agacctcaaa gggactcttg aaatgattat caagaagatg
    26581 ttcggtgaag aacgtagcat tcgtttgcgc ccgtcatatt tcccgttcac agaaccatct
    26641 gttgaagtgg atgtttcttg ctttaaatgt ggtgggaaag gctgtaatgt ctgcaagaaa
    26701 acaggatgga ttgaaattct tggtgctggt atggttcacc caagtgtctt ggaaatgtca
    26761 ggtgttgatg caaaagagta ttcaggcttt gcctttggtt taggtcaaga gcggattgcc
    26821 atgttgcgtt atggcattaa tgacattcgt ggtttctatc aaggcgacca acgtttctct
    26881 gaacaattta actaaaatga gtcgtttgaa gacttctgtc agctatttta tctaagattg
    26941 agtgaaagtt gataggtaat gataataggt taattgtcta aggggaaagt ccctctcgct
    27001 tcaacgtcat aagggttttg acttggaact taaaatacga aaggaaatga ctcaaatcac
    27061 ggcttgagag ctttctctag ccgagtgatt tgggcactaa aattatgtta gtatcttata
    27121 aatggttaaa agaattagta gatatcgatg tgacaccagc agcacttgct gagaaaatgt
    27181 cggcaacgag tatcgaggta gaaggaattg aagtccctgc agatggttta tcaaaactgg
    27241 ttgtggggca tgtgctttct tgcgaagatg tgccagagac acatttgcat ttgtgtcagg
    27301 tagatacagg tgatgaaacg ccacgtcaaa ttgtgtgtgg cgcaccaaat gtgaaagcag
    27361 ggattaaggt tatcgtggct gtgccaggtg ctcgtattgc ggataactat aaaatcaaaa
    27421 aaggcaaaat ccgcggcatg gaatctcttg gcatgatttg ttccttgcaa gaacttggtt
    27481 tgtcagatag tattattcca aaagaatttt cagatggtat tcaaatcttg ccagaggagg
    27541 ctgtgccagg tgatgctatt tttaaatacc tggacttgga cgatcatatc attgaattgt
    27601 ccattacacc taaccgtgct gatgcgcttt ctatgcgagg tgtggcacat gaagtcgcag
    27661 ctatttatgg caagtcagta tcattccccc aaaaaaatct acaagaatct gataaggcaa
    27721 cttcagaagc cattgaagtg gccattgcct ctgataacgt tctaacttac gctagccgtg
    27781 tcgttgaaaa tgtcaaagtt aagccaagtc cacaatggtt gcaaaacctt ttaatgaatg
    27841 ctggtattcg tcctattaat aatgtggttg atgtgaccaa ctatgtgctc ttgtattttg
    27901 gtcaacctat gcatgctttt gattatgata aatttgaaga ccataagatt gtggcgcgtg
    27961 cggctcgtca aggggaaagt ttagtcacac ttgatggtga aaaacgggat ttgaccactg
    28021 aggatcttgt tattaccgtg gctgacaaac cagttgcttt ggcaggtgtt atgggtggtc
    28081 aagccactga aattgatgcc aactctcaga cggttgttct tgaagttgct gtttttgatg
    28141 gcaaatcgat tcgtaaaacc agtggtcgtt taaaccttcg ttcggaatcc tcttcacgtt
    28201 ttgaaaaagg ggttaactat gcaactgttt tagaagcgct tgactttgca gcggctatgt
    28261 tacaagaatt agcagaaggt caagtcttat caggccatgt tcaagctgga caattgccaa
    28321 cagaacctgt tgaagtctca actagccttg actatgtgaa tgttcgttta ggaacagaat
    28381 taacttttgc tgatattcaa aggatttttg accaacttgg atttggtcta acaggagatg
    28441 aaacaagctt cacggtagct gttcctcggc gtcgttggga tgttagtatt ccggctgatt
    28501 tggtggaaga aattgcgcgt atttatggtt atgataagtt gccaacaacc ttaccagagg
    28561 caggaggaac ggctgcagaa ttaacgccaa cacaggctct tcgtcgtaag gtccgtggtt
    28621 tagcggaagg attgggcttg actgaaatca tttcgtatgc cttgacaaca ccagagaaag
    28681 ctgttgagtt tgcagtggca ccaagtcacc taacagaact catgtggcca atgtctgtgg
    28741 aacgttcagc gcttcgtcaa aatatggttt cagggatgtt agatacggta gcttataatg
    28801 tggctcgtaa acaaagtaac ttggctcttt atgaaattgg aaaaatcttt gaacaagaag
    28861 ctaatccaaa agaagacctt cctaatgaat tgaaccattt tgcttttgct atttgtggct
    28921 tagtggcaca aaaagatttc caaacccaag ctcaggcagt ggatttttac catgctaaag
    28981 gtatcttgga tactttattt gcaaacctta acctcaaggt tcaatatgtg ccaaccaaag
    29041 acctagcaag catgcaccca ggacggacag cgcttatcct attagatgag caagtgattg
    29101 gatttgttgg tcaagttcat ccaggaacag caaaggctta tagtattcca gaaacctatg
    29161 tggcagaatt ggatatggct gctttagaag cagcgttgcc aagtgatcaa acttttgcgg
    29221 aaatcacaaa attccctgct atgacacgtg atgttgcctt gttacttgac cgtgaagtga
    29281 gtcatcaggc cattgtaaca gctattgaat cagcaggtgt aaaacgcttg actaagatta
    29341 agctctttga cgtgtatgaa ggagtaacta ttcaggctgg caaaaaatca atggcttata
    29401 gccttacttt ccaaaatcca aatgacaatt taacggatga agaagttgcc aaatacatgg
    29461 agaaaatcac caaagcattg acagaacaag tcggtgctga agtacgctaa gaaaaaaact
    29521 gggcctctaa ggctccgttt ttttctgtta taatagagga aaaaagaact ccagttcaaa
    29581 tgattggaga aaaacatcag aaggtggagg aaaatcagaa tgtatcaaac aaaaataaca
    29641 ggcaaccgcc tttaccacac ggtttcgaaa ggctacggag atagtgtaac cttatttgga
    29701 aaaactgatc aaggggaaac ccctatgagt ttactggtta ttgccttgtc ttcttgtgtg
    29761 actatgtgtg tgcagggttt ttaccatcgt caatttcagc aagacacact tgctgtttct
    29821 gttgaggcta gttatgagga agaagttttt gaactacttg ttaggattga tgatgtttta
    29881 gatgacaaaa agaaagctga tttgttggct tacattggaa cttattgtcg tgtgaaacaa
    29941 ctcctcaaac ctgaagttat ggtgaccatt acgttggaag gactgtctca tgtctgatgc
    30001 tggtttgaaa acttaccaaa aacaatgggc ttatcaaaag tattgggtca tggcacactc
    30061 acagcagcat tacaatgctt taagagaatt gtttaaagga aatcagtggt cagaagaaaa
    30121 ggtgttgact tttcattgtt tgattgaaga agcgcaagcc attcctccca cagtaaaaag
    30181 cttacgaaca gcatatcagc atgtttgggg gtattttaaa aaggtagcga gtcaggaaga
    30241 aaaagaccat ttcaaagatt tggatgctca gttggaaact aaatctgagg agatgctatg
    30301 ctttttacaa gagatgacgg ctcattatca gccctcttat ctgctatctt gccgtttgat
    30361 taccaaaggt ccttaaatgc taaacagaaa agtagggact tctgggaagt tatgctaagc
    30421 tagtgatata aacaaggggg aatgagagat gtttttagcg cttaatgaaa tgaaacaatc
    30481 caaattgcgg tatggtttga ttgctggttt gctatgtttg gttgcctatt tgatgttctt
    30541 tttgtcagga ttggcctttg gtttgatgca ggagaaccgc tcggcggttg atctttggaa
    30601 agctgacagt attttactag ccaaggatgc tgacgctacc ttgaccttat cacaggtgtc
    30661 cagagctcaa gaaaatcaaa taacagcaga caaggtagct cctcttgctc aactcaatac
    30721 cgtggcgtgg tcagttaaaa atcctaagga tgccgacaaa gttaaggtta gccttttcgg
    30781 gattgattct aatagcttta ttcgtcctaa cattgtaaaa ggtcgattat ttaagactaa
    30841 caaagaggtt gttttggatc aaagccttgc aaaagaggaa gcttttgcga ttggcaagga
    30901 cttttacaca tcgagttcga gtcaagcatt aactatcgtt ggttatactc aaaatgctag
    30961 atttagtgtt gcaccagtgg tttatatgaa tctggaagct tttgaaacat taaaatatgg
    31021 agaaccacta ccaaaagata agcaagttgt taatgctttt atcactaaag gaagtttaac
    31081 agattatcct aaaaaagact tccaaaaatt agatattaaa acctttatta ctaaattacc
    31141 tggttatagc gctcaacttt taacgtttgg ctttatgatt agttttcttg tcattatttc
    31201 agctattatt attggtattt ttatgtatat tttgactatt caaaaggcac ctatttttgg
    31261 gattatgaaa gcgcaaggaa tttctaacaa aacgattacg accgctgtgc ttatgcagac
    31321 attctttttg agttttttag gtagtggttt agggttgcta ggtacttggc tgacatcatt
    31381 attattacca acagtagttc cttttcaaag caattggttt ttatatttgg ctatattcgt
    31441 tagtatgatc tgttttgctc tattaggcac cttattttct gtttttaaca ttatacgaat
    31501 tgatcctttg aaagcaattg gataggaggt agtgatgtcg gttttaacat ttaaacaagt
    31561 gaccaaaaca tttcaagatg gtcatcacga aatcaacgca ttaaaggcaa ctgacttttc
    31621 cattgaagct ggagaatttg tggctattat tggaccatca ggttctggaa aatcaacctt
    31681 tttgaccatt gctggtggct tacagacccc aagttctggt cagctaatca ttgatggcac
    31741 tgattatacg catttatcag aaaaagagcg ctcacgcttg cgcttcaagt ccgttggttt
    31801 tatcttacaa gcttccaatc tgataccttt tttaacagtc cagcagcagt tggaattggt
    31861 cgatcatttg acaggaagca aagaaaaagc caaagccaat cagttatttg acgatttagg
    31921 cattacaggg ctaaaacatc agttacctca agaattgtcc ggcggagaaa ggcaaagagc
    31981 ggcgattgcc cgtgctctct accatgatcc agcactgata ttggcagacg aacctactgc
    32041 aagtttggat actgaaaaag cctatgaagt ggtcaaactg ttagctaagg aaagtaaaga
    32101 aaaaaacaag gccattatta tggtcactca tgatgatcgg atgctaaaat attgtgacaa
    32161 agtctatcgg atgcaagatg gagagttacg tcaagagaga tagtagactg gtaagagttt
    32221 atgatattag aagaaaaaaa ccaaacaagc acagcacttg tttggttttt ttctaagtgt
    32281 gactattatc aatacgtcac catttcccta aagcttacta tacgggatgc taaaggtatc
    32341 accatgctca aagtcgccat attggtaacc tcggtcaaac caacgttggc gttgcttaga
    32401 agtgccatgt gtaaaactat caggaacggt tctgccatag gtttcttctt gcagagtatc
    32461 atccccaact gcgtgagctg ctgccattgc ttcctcaata tctccttttt ccaaaaggcc
    32521 ttgcccttga acataattag cccaggcacc agcatagtaa tcagcttgta attccaactt
    32581 gacgttgagc tgattggctt tagcctttga ttttccttgt ctagcgctag cgtaattatc
    32641 cataattccc aattcatttt ggatgtggtg gccaacttca tgagcaatca cataggccat
    32701 agcaaaatca ccttttgcgc cgtacttggt tgatagttca ttataaaaag aaatatctaa
    32761 atacactttt tgatcgcctg ggcaataaaa aggaccagaa gaggcttgac ccctgccaca
    32821 agcggtttga gttgctccag tatatagaac taatgttggt ttatgataag ttaacccttt
    32881 ctcacgaaat gtcttagtcc aatagtcctc ggtagaggcg aagaccttac tgacaaaaga
    32941 aacctgttct tgactagcct tgtcaccatt tgtacgcgtt acttggcttg attgataggc
    33001 attgttgttg gtagaagaag gcttgcctcc taaaacacta gataggccac cccctcccat
    33061 aactaggaga aggagaagaa taaccagctt ggttttccaa cctcctcgtg aaaagagtaa
    33121 ttgaagcagg agaccgcccc ctaggccgcc gcccccaaaa gaaccagacg attgaccacg
    33181 tctatcttca acctgttgac tttctctcaa atcatccgtt ttcataagtt tctcccatct
    33241 atttcttgat tttattataa aataattcta ttagaattgc tatttttatg atgagattat
    33301 aactaaaaat aggaaaagca ataggtattt gctataatat aacaagggta gattcagttt
    33361 gtataaagga gtcatatgaa attaatttac acagagatga gttactcgat gacagagatt
    33421 ttggtgaatg aagcacgaaa agctgctgac caaggttatc gagtgttcta tattgctcca
    33481 aattctcttt catttgaaaa ggaaagagaa gtcttaacct tattgcctga acgagggact
    33541 ttttcgataa tagtaacccg gttcgttcaa atgtcaaggt attttacagt tgagagctct
    33601 ccttctaagc aacatctaga tgacacgact ttggctatga ttttttatcg ggccttgatg
    33661 caattaaaac cagaagattt gccgagttat ggtcgtttgc aaaataattc ggtttttatt
    33721 gaacaactag ttgagttata taaggaatta aaaaacgcac aattaagcgt acatgattta
    33781 acaggattag accatcctca aaaacaagaa gatcttatta aaattattga gcttgcagag
    33841 acgatcatga ttcagcaaga ttataatcaa gatagtcctc tacaatcttt tgcaagagca
    33901 attaagttag gacttttaaa taaccaacta tcaaaaacag ttattgttat tgatggtttt
    33961 tcacgttttt cagctgaaga ggattattta ttatcacttt taaataacaa ctgtcaagag
    34021 gtcatcattg gcagttatgt gagtcaaaaa gcttatcaaa aatcttttat taagggaaat
    34081 atctatgagg ctagccttca ttttttgcaa gatttggctc aaaaatacca tatcaagccg
    34141 gtatttgcga cctctaatca agtgtttaaa ccagcctttt cacggctaac acaattattt
    34201 gaagcaactc atgatttttc acaagtagac tggcaactcc aaaagaatga tcttgatcac
    34261 tttagccttt ggcaatgtca tcatcaaaaa gaggaaattg aacatgtagc aaaatccatt
    34321 cggcaaaagc tatatgaagg ttaccgttat aaggatatct tagtgttgct aggagatatg
    34381 gatgcttatc aattacaaat tgggcctatc tttgataagt ttgaaatccc ctactattta
    34441 ggaaaagcag agcctatggc tgcccatcca ttagtccaat ttatagaatc gctcgaacga
    34501 agtcagcgct ataattggcg tcgtgaagac attttaaaca tgttaaaatc aggacttttt
    34561 ggttgttttg atgatagtga tattgatcgc tttgaggaat atactcagtt tgcagatatt
    34621 aaaggattta ctaaattttc aaagcctttt accattaact cttctaggca gtatcctctt
    34681 gactttttaa atgaaatgag acaagacatc gttttacctt tgcaagaatt gtttaagagt
    34741 caaaaacaac ttggtgcttc acttgttgac aaattaatac ttttttttaa aaagattaga
    34801 ttagctgaga atatgcaagg tttagcacag tcccaattag aggtggaaaa aaacgaagaa
    34861 gtttggaaaa ggtttacaga tattttgact tcttttcatc atatctttgg ccaagaaaaa
    34921 ttacggctat cagattgcct tgctttaatc aaaacgggaa tgaaatcagc tcagtatcgt
    34981 gttgttccag cgacattaga tgttgtcact attaaatctt atgaccttgt tcaaccacat
    35041 tcaaaacctt tcgtttatgc aattggtcta actcaatcac attttcctaa gcaaattcac
    35101 cattcaggac tactttctga tcaagagcgt gctagaatta atgaaataag aaattatcgt
    35161 cattttgata ttgctagtgc cgaaaatagt aaaaaaaacc atcaaactgc gttatctctg
    35221 tttaatgctg ctactaaaga gttagttctt agtgttccaa cggtaatcaa cgagacattc
    35281 gatgatctat ctccttatct taaagaatta ataagctttg ggctacctct tttggataaa
    35341 ggcaaaaact atctatctta tgataatagc gatattggta actataaagc tctcttgtca
    35401 caaattattg ctattaaccg acaagatctt atagaaatgt cagatcaaga taagatgttt
    35461 tggactgttg tcttacgtta tctcaggaaa cagttaagaa agcaacagct agagctacct
    35521 acttcagatt atcgtttatc aacaaagcct ttgtctaaag aagttatcga ggtatgtttt
    35581 ccaaagggaa tccctttaaa gctatctgca actgctttaa ccgtttttta taataatcag
    35641 tacaactatt ttttgaaata tgttttgaat ttaaacaaaa cagaatccat tcatccagat
    35701 tccagaattc atggtcaata cttgcatcgt gtctttgagc ggttaatgaa agatcacacg
    35761 caagaaccgt ttgataataa attaaaacaa gcaatctacc ataccaatca agaaagtttt
    35821 tttcagcagg tttaccaaga taatgccgag gctgagtaca gtttagctat actagaagat
    35881 attgttagat caacagcacc tatcttgcaa cttaaccaaa acataaaggt cattgatcaa
    35941 gaaaagaact ttcatctgga tatgggaaat gagatattag tccacgggat cattgatcgt
    36001 attgaccagc tgagcgacgg tagcttgggc attgttgact ataaatcaag cgcgaatcaa
    36061 tttgatattg ggacctttta taatgggttg agtccacaac tagtgactta cctcgcagcc
    36121 ttaaaacaga tcgcaccgca cgatataaac caattatttg gggctatgta ccttcatttg
    36181 caagatccta aattggatct agtaacattt aaacaaattg ataacacatt agtggagagt
    36241 atctataaag cgttgaccta taaaggtatt ttttcagaag tcgaaaaaga gcatctatct
    36301 actggtgctt accaaaccaa aaatgctctt tattccaatg acgaattgga aacactttta
    36361 aattataaca agtacctcta tcttaaagct gctaaacaca ttaaaaaggg acattttttg
    36421 attaatcctt atacaagcga tggtaagaca gttcaaggag atcaattaaa agccattacc
    36481 cgttttgaag cagatcttga catggcacag gcaaggcgac tagtgactct ccctgctaag
    36541 gagaaaaaag agtgcttttt aacattaatg agaaaggaga gccacttgtg atttcttttg
    36601 ccccattttt aagccccgaa gctattaaac atttacaaga aaacgaaagg tgcagtgatc
    36661 agtctcaaaa acgcacagct caacaaattg aagcaattta tactagtggc caaaatatac
    36721 ttgtatcagc ttctgctggt tcaggaaaaa cctttgtaat ggtcgaacgc atacttgata
    36781 aaattttgag aggtgtttca attgatcggc tttttatctc aacctttact gttaaagcag
    36841 ctacagaact gcgtgaacgg attgaaaaca aattatactc acaaattgct caaactacag
    36901 attttcaaat gaaagtttat ttaacagaac aattgcaatc tcttggtcaa gctgatattg
    36961 gtactatgga tgcttttgca cagaaagtag taagtcgcta tggttatagc attggcattt
    37021 catcccaatt tcgtatcatg caggataaag cagaacaaga tgttttaaag caagaggtgt
    37081 ttagcaaact ctttagtgag tttatgaatc aaaaagaggc accggtgttt agggctcttg
    37141 tgaaaaattt ttctggtaac tgtaaagaca cttcagcttt tagagagtta gtttatactt
    37201 gttattcttt tagccaatcg acagaaaatc caaaaatatg gttgcaagaa aattttctaa
    37261 gcgctgctaa aacttaccaa aggcttgaag atatcccgga tcatgatatt gaactcttac
    37321 ttttggcaat gcaagacact gcaaatcagc taagagatgt gactgatatg gaagattatg
    37381 ggcagctgac taaggcaggt agccgatctg ctaaatacac taaacactta acgatcatag
    37441 aaaagttgtc tgattgggtg cgtgatttta aatgtttgta tggaaaagcc ggattggatc
    37501 ggttgatcag agatgtgaca ggccttatac catctgggaa tgatgttaca gtctcgaagg
    37561 taaaataccc tgtttttaag accttgcatc aaaaattaaa acaatttagg catttagaaa
    37621 caattttaat gtatcagaaa gactgttttc ccttattgga acagttacaa gattttgtgc
    37681 ttgcgttttc agaagcttat ttagctgtca aaatacaaga aagtgctttt gaattttcag
    37741 atattacaca ctttgcaatc aaaattttag aggaaaatac ggatattcgc caattctatc
    37801 agcaacacta tcatgaggtg atggttgatg aatatcaaga taacaatcat atgcaagagc
    37861 gactcctgac cttactatcg aacggtcata atcgctttat ggtaggagat atcaaacaat
    37921 cgatctatcg atttcggcaa gccgatcctc agatttttaa tcaaaagttt agagactatc
    37981 aaaaaaaacc tgagcagggg aaagtgattt tactcaaaga aaactttcgt agccaatcag
    38041 aggtgttaaa tgtcagcaat gctgttttta gtcacttaat ggacgaatca gtaggagacg
    38101 tcttatacga tgagcaacat cagttaatag caggtagtca tgctcaaaca gtcccctatc
    38161 tagaccgtcg tgctcagtta ttgctatata atagcgataa agatgatggc aacgcccctt
    38221 cagatagtga gggtatttca tttagtgagg ttacaattgt tgccaaagaa attattaagc
    38281 ttcacaatga taagggtgtc ccttttgaag acattacgtt actcgtttct tcaagaacaa
    38341 gaaatgatat catttctcat acattcaatc aatatagtat tcctatagta acagatggtg
    38401 ggcagcaaaa ctatcttaaa tctgttgaag tgatggttat gttagataca ttacgcacca
    38461 ttaataaccc aagaaatgat tatgcccttg tggctttact gcgctcaccg atgtttgcct
    38521 ttgatgagga tgatttagca agaatagcac ttcaaaaaga caatgagcta gataaagatt
    38581 gcctatatga caagatacaa agggctgtga ttggaagagg tgctcatcct gaattgattc
    38641 acgatacctt gcttggcaag ttaaatattt ttttaaagac gttgaaaagt tggcgtcgat
    38701 acgctaagct agggtcgttg tatgacttga tttggaaaat ttttaatgat cgtttttatt
    38761 ttgattttgt agctagtcaa gcaaaagcag aacaagcaca agctaatcta tacgcattag
    38821 ctctacgtgc taatcagttt gaaaaatcgg gctataaagg gctataccgt tttattaaaa
    38881 tgattgataa ggtacttgag acgcaaaatg acttagcaga tgtggaagtg gctgctccta
    38941 aacaagctgt taatttaatg accattcaca agtctaaagg tttacaattt ccgtatgtat
    39001 ttatccttaa ttgtgacaag cgcttctcaa tgacagatat tcataaatca tttattctga
    39061 atcggcagca cggtatcggt atcaagtacc ttgcagatat caaaggttta cttggtgaaa
    39121 caacactcaa ttctgttaaa gtaagcatgg aaaccttacc ttatcaattg aacaaacaag
    39181 agttgcgctt agcaacttta tcagaacaaa tgcgcttatt gtatgttgct atgacacgag
    39241 ctgaaaaaaa agtttatttt attggtaaag ctagtaagag caaaagtcaa gatatcacag
    39301 atcctaaaaa gttaggcaaa cttttgccgc tggctttacg agaacagtta ttgacattcc
    39361 aagattggct attagcaata gcagatatat tttcaactga agatctttat tttgatgttc
    39421 gctttattga agatagtgat ttgacacaag agtcagtcgg acgacttcaa acaccacagt
    39481 tattaaatcc agatgatctt aaagataatc gtcaatcaga aacaattgca cgggctttag
    39541 atatgttaga agcagtgtct caattgaatg ccaattatga agcagctatt catttgccaa
    39601 cagttcgaac gcctagccaa cttaaggcag cttacgagcc tttattagaa cccattggtg
    39661 tagatattat agagaaatct tctcgatcgc tatctgattt tactttgcca catttttcaa
    39721 aaaaagtaaa agttgaagca agtcatattg gatcagctct tcatcagttg atgcaggtgc
    39781 tccctttgtc aaaaccgata aatcaacaaa cgcttttaga cgctttaaga gaaattgata
    39841 gtaacgaaga ggtaaaaaca gctcttgatc tcaaaaaaat agagtcgttc ttttgtgata
    39901 caagcctagg ccaatttttt cagacttacc aaaaacactt gtatcgagaa gcaccatttg
    39961 ctattttaaa agttgaccct attagtcaag aagaatatgt cctacgtggt attatagatg
    40021 cctacttttt gtttgatgat catattgtat tagtggacta taaaacagat aaatacaagc
    40081 agcccattga gttaaaaaag cgttaccaac aacagttgga gttatatgca gaagctctca
    40141 ctcaaacgta taaacttcct gtgactaagc gctatcttgt tttaatggga ggtggaaagc
    40201 cagaaattgt cgaagtttaa ggttgttgtg acacaagggt attttgcaaa tgataatagt
    40261 atagttgagg attttacgaa atgcttgaaa agctattgac ctttgaataa taatacaata
    40321 taataagttt tattagtgac aaaaaggaat aaatatacta tgaattttaa aaaaataaga
    40381 tttggttttt tgctttgcct cctactttat cctttagcag cttgtaataa gtctgaacaa
    40441 cttaatcact acgaaagaat taaaaaaaca agaaaattag tcgttgctgt aagccctgat
    40501 tatgctcctt ttgaatttaa agctttagtt aatggaaaag atactattgt tggagcagat
    40561 gttcaattag ctcaggctat tgctgatgaa ttagacgttg atcttgagct ttcaccaatg
    40621 agttttgata atgttttgtc tagtttacag actggtaaag ctgatcttgc tatttcagga
    40681 atctcacata ctaaagaaag agctaaagta tatgattttt caattcctta ctatcaggca
    40741 gaaaacgcta tagtgatgag agcatctgat gctaaagtga ccaaaaatat tagtgaccta
    40801 aacggtaaga aagtagccgc tcaaaaaggt agtatcgagg aaggtttagt taaaatacaa
    40861 ttaccaaagg ccaatctgat ttctttgact gctatgggag aagccattaa tgaactaaaa
    40921 gcaggacaag tctatgcagt taccttagaa gcacctgtag ctgctggttt tttagcccaa
    40981 cataaggatc tggctttagc accctttagc ttaaaaacca gtgatggaga tgccaaagca
    41041 gtggcccttc ctaaaaatag tggtgactta accaaagccg ttaataaggt tattgctaag
    41101 ttagatgagc aagaacggta caagtcattt attgcagaga caatagcact aacgaaaaat
    41161 actatgaagt aataaggtta ataaaaactt tattagtatc cgttggaaaa gtgtttagaa
    41221 taaacaataa aagaggtttg acttttttta aaaaataatg taatataatt gggaacgtga
    41281 aaatgttaca atatcttgag gaggtgaaac acatgtcaaa aacagtagta cgtaagaatg
    41341 aatctcttga cgatgctctt cgtcgcttca aacgttctgt tactaaagct ggtactcttc
    41401 aagaatcacg taaacgtgaa ttctacgaaa aaccttctgt aaaacgtaaa cgtaaatcag
    41461 aagcagctcg caaacgtaaa aaattctaat ggtaaaaaat aaaaacagtt ctcacaatta
    41521 gaactgtttt tattttttat ccagaagaag caagggagct tttttgatat caaaaaaagc
    41581 agttagacat gcctaactac tttatcaaaa atcgctttat ttttgagcca acaaatcacg
    41641 gatttctgtc aataattctt cttgagtagg agctgcagct tctttttctt ttttaggcat
    41701 agctttttca gcggctttta caacaaagaa aagactggta ccgatgataa gaaaattaat
    41761 aacggctcct aaaaagctac catatttaac accattccat gacaattgag tgatgttttc
    41821 aacatttgcg gccttcagag ctgggtttaa aataagcggt gtgataatat cgttcacaaa
    41881 agaagtgaca atagcaccaa aagctccccc gatgataact gctacagcaa gttcaataat
    41941 gtttcctcta aacaaaaatg cttttaattc tttaaccatt aaatattccc ccttttaata
    42001 tctctaagtt aagcatagca taattagtaa acaaaatcca atggaatcac ttcagttttt
    42061 aaatttacaa aaaagagttt cggtggtata ataaaacgta aaactagaat gggattttta
    42121 tggggaggtg acgatttggc aattgacaaa gaaatgattt cccaagtaaa aaatagcgtt
    42181 aatattgtcg atgtcattgg agaagtggtc aaactttccc gatcagggcg gcattatctc
    42241 gggctttgcc catttcataa ggaaaagaca ccctctttca atgttgttga agacagacaa
    42301 ttttttcact gctttggctg tggaaaatca ggggatgttt ttaaatttat tgaggaatac
    42361 cgccaagtcc ccttcttaga aagtgttcag attattgccg ataagactgg tatgtcgctt
    42421 aatataccgc caagtcaggc agtacttgct agccaacaca agcaccctaa tcacgctttg
    42481 atgacacttc atgaggatgc tgctaaattt taccatgcag ttttgatgac cactaccatt
    42541 ggtcaagaag ctaggaagta cctttaccag agaggcttgg atgaccaatt aattgagcat
    42601 ttcaatattg gtttagcccc agatgagtca gattatcttt atcaagctct ttctaaaaaa
    42661 tacgaggaag gtcaattggt tgcttcagga ttgtttaact tgtccgatca atccaatacc
    42721 atttacgacg cctttcgaaa tcgtatcatg tttcccttat cagatgaccg agggcatatt
    42781 attgcctttt caggacgtat ctggacggca gctgatatgg aaaagagaca ggccaagtat
    42841 aaaaattcaa gaggaacagt tctttttaac aaatcttatg aattgtatca tctggacaaa
    42901 gcaaggcctg ttattgccaa aacccatgaa gtgtttctaa tggaagggtt tatggacgtg
    42961 attgccgctt accgttccgg ctatgaaaat gctgttgctt caatggggac ggcattgact
    43021 caagaacatg tcaatcacct taagcaagtc actaaaaaag ttgttttgat ttatgatggt
    43081 gacgatgctg gacaacatgc tattgcaaaa tcactagaat tgcttaaaga ttttgttgtc
    43141 gaaattgtca gaatccccaa taaaatggat cctgacgaat ttgtacaacg gcattcccca
    43201 gaagcatttg cagatttgct taagcagtca cggatcagta gtgttgaatt ttttattgat
    43261 tacctaaaac ctactaatgt agacaatctg caatcacaaa ttgtttatgt ggagaaaatg
    43321 gcaccattga ttgctcaatc accatccatc acagctcaac attcgtatat taacaagatt
    43381 gctgatttgt tgccaaactt tgactatttt caagtagaac aatcagtaaa tgcattaagg
    43441 attcaagata ggcaaaagcg tcaaggtcaa atagctcaag ccgtcagcaa tcttgtgacc
    43501 ttaccaatac caaaaagttt gacagctatt gctaagacag aaagtcatct catgcatcgg
    43561 ctcttacatc atgactattt attaaatgaa tttcgacatc gtgatgattt ttattttgat
    43621 acctctacct tagaaatact ttatcaacgg ctgaagcaac aaggatacat tacatcttat
    43681 gatttgtcag agatgtcaga ggaagttaac cgtgcttatt acaatgtttt agaagaaaac
    43741 cttcccaaag aagtagctct tggtgagatt gatgatattt tatccaaacg tgccaaactt
    43801 ttagcagagc gcgatcttca caaacaaggg aaaaaagtta gagaatctag taacaaaggc
    43861 gatcatcaag cggctctaga agtactagaa cattttattg cgcagaaacg aaaaatggaa
    43921 tagaggaaat tatgacaaaa caaaaagaaa taacaacttt taacgttcaa gttgcggagt
    43981 ttattcgcca tcacaaaaaa gaaggaacag cgattgatga tgacgtgacc gaaaaacttg
    44041 tcattccatt tgctttggat gctgatcaga ttgatgattt acttgagcgg ttaacagatg
    44101 gtggtatctc gattacggat aaagaaggta acccatcatc aaaatacatt gttgaagaac
    44161 caaaaccaga agaattaact gatgaagaat taattggtag taattcagct aaagtaaacg
    44221 accctgtccg catgtacctc aaagaaattg gtgtggtacc gcttttaaca agtgaagagg
    44281 aaaaagaatt ggctgttgca gttgccaagg gagatttaat ggctaaacaa cgtttagcgg
    44341 aagcaaacct tcgtcttgtt gtctcaattg caaaacgtta tgttggacgt ggaatgcaat
    44401 ttcttgattt aattcaagaa ggtaacatgg gactcatgaa agctgttgat aaatttgatt
    44461 attcaaaagg attcaaattc tcaacttatg caacatggtg gattcgtcaa gctataacac
    44521 gcgcaattgc agatcaagca cgtacgattc gtatccctgt tcatatggtt gaaacgatta
    44581 ataaattagt ccgtgaacaa cgtaaccttc ttcaagaact tggtcaagat ccaacgccag
    44641 aacaaatcgc agaacgtatg gaaatgactc cagacaaggt tcgtgaaatt ctaaaaattg
    44701 ctcaagaacc tgtttcttta gaaacaccaa ttggggaaga agatgatagt cacttaggtg
    44761 attttatcga agatgaagtt attgaaaatc cagtagatta tacgacgcgt gttgttcttc
    44821 gtgagcaatt ggatgaagtt ttagatacgc ttactgaccg tgaagagaac gttcttcgcc
    44881 tacgctttgg ccttgacgat ggtaaaatgc gtacgttaga ggacgtaggt aaagtcttta
    44941 atgttactcg tgagcgcatt cgacagattg aagctaaagc ccttagaaaa cttcgccatc
    45001 ctagtcgtag taaacaatta agagacttta tagaggacta aaatcgtcca gtggacgatt
    45061 ttaggtcgtt cctttgaaat aagaaaggag cgaaaatcct aagtggcact tatcagcggt
    45121 acacctacaa attagaaatc ggaccgaatg tggtgggtat ttttaaggtt ggacttgata
    45181 tcttaaacaa gcccagaggg caattcctct aaataggcaa agctttagtg gtttttttac
    45241 ttatctacga catattcaaa aaatgaaagg aaagccatgt ctgatacacc aaaatataca
    45301 caagatcagg tgatagctat caagaataga attcttgaag ctttagaaac tgttattgat
    45361 cccgagctag gtattgatgt tgttaatcta ggtttgattt atgaaattcg gttcaatgat
    45421 aacggttata cagagattga tatgacactc acaacaatgg gttgtccttt ggcagacttg
    45481 ttgacagatt acatccatga tgccctgcaa gatgtgccag aagtcactaa gactgaggtc
    45541 aaattagtct ggtaccctgc ttggacggtt gataaaatga gccgctatgc taggattgcg
    45601 ctgggtattc gctaatcatt gatagtaaag ggatgaaata ttcccttttt tgatgtagaa
    45661 taaaaggaaa tacaggtgaa agcctttggt taatgttaga gaacactaag atactgagaa
    45721 aagtgttcta cctatggcaa aaaggagaac tgatgatttt aattacagga agcaatggtc
    45781 aattaggaac agaacttcga tacttattag atgaacgagg tgttgattat gtagccgttg
    45841 atgtcgcaga aatggacatc acaaatgaag acaaagtcga agctgttttt gcgcaggtca
    45901 agccaacatt ggtctatcat tgtgctgctt atacggcagt tgatgcagca gaagacgaag
    45961 gaaaagcctt gaatgaggct attaatgtaa caggctcaga aaatattgcc aaggcttgtg
    46021 gaaaatatgg ggctaccctt gtttacattt caacagacta cgtatttgat ggcaataaac
    46081 cagtcggtca agaatgggta gaaacagatc gtccagaccc taagacagaa tatggccgta
    46141 caaaacgttt aggagaacta gctgttgaac gatacgcaga gcatttttat attatccgta
    46201 ctgcttgggt atttggaaat tatggtaaaa actttgtctt tgccatggag cagttagcgg
    46261 aaaatcactc ccgtttgact gttgtcaatg accaacacgg tcggccaacg tggacaagaa
    46321 ccttggcaga attcatgtgt tatttgacag agaatcaaaa agcctttggt tactatcact
    46381 tgtcaaatga tgctaaggaa gacaccactt ggtatgattt tgccaaagaa atcttaaaag
    46441 acaaggctgt tgaagtggtg ccagttgatt catcagcttt cccagcaaaa gccaaacgtc
    46501 ctttaaattc aaccatgaat cttgataagg caaaagcaac agggtttgtt attccaacat
    46561 ggcaagaagc cttgaaggca ttttaccaac aaggactgaa aaagtaagta ttctaaaaag
    46621 agttggcttt ctaaggccaa ctctttttca tgggtttaag gtcgcattag ccttctaatt
    46681 gtggtataat atcactgatt atattttaga atggggtagt atgcaatgca ggatgttttt
    46741 atcattggta gcagagggtt accagcgaaa tacggtggct ttgaaacctt tgtcgaagag
    46801 ttgattagtc atcaatcatc taaaaacatt cgttatcacg ttgcttgttt aagcgatacg
    46861 aagcataagg ttcattttga ttataagggg gcagattgct tttaccttaa tcccccaaaa
    46921 cttggtcctg ctagagttat tgcttatgat atgatggcaa ttacctatgc cctgtcttat
    46981 agcgaccaac accagattca gaaccctatt ttttatgtgt tgggcaatac tgtaggcgct
    47041 tttattgcgc catttgtgaa gcagattcac aatcgaggtg gacgcttttt tatcaatcca
    47101 gacgggttag agtggaaacg gtctaaatgg tcaaaaccag tgcaggccta cctgaagttt
    47161 tccgaaaagc aaatgactag acaggctgat ttggtcattt cagataatat tggcattgac
    47221 cgctacctta aacaggttta tccttggtct aaaacatgtt ttattgctta tggaacgcag
    47281 acacaacctt cacgtttgac aacagcagat agcaaggtca gagcttattt tcaaaccttt
    47341 gatattagag aaaaggatta ctatctcatt ttaggacgct ttgttcctga aaataattac
    47401 gaaactgcta ttaaagaatt tatggcttcc tcaactaagc gtgatttagt gattatttgt
    47461 aatcatgaag acaatgctta ctttaagcaa ttacttgctg agacagagtg tgataaagac
    47521 ccacgcatta aatttgttgg taccctttat gacaaagaac tattagccta cattcgagaa
    47581 caggcttatg cctatatcca tggtcatgag gtaggaggga ctaatccagg ccttctagaa
    47641 gcactagccc ataccaatct taatttggtt ttaggagttg attttaacca gtcggtggct
    47701 aagtctgctg cgctgtattg gtccaagcaa aaagggcaat tagcagagct gattaaccaa
    47761 gttgatgcag gttttgatag tgatcgtctg ggcaaagaag ccaaagctat tattcaagaa
    47821 cattacactt gggaaaaaat tgtaggggag tacgaggctt tatttttaaa tgaacattaa
    47881 tattttacta tccacctaca atggagaacg cttcttagca gaacaaattc aaagtatcca
    47941 aaggcaaaca gttaacgact ggaccttatt gattagagat gatggatcaa ctgatggcac
    48001 ccaggatatt attcgcacat ttgtcaagga agacaaacga attcagtgga tcaatgaggg
    48061 gcagacagaa aatctgggag ttattaagaa tttttacacc ctcttaaagc accaaaaagc
    48121 agatgtctat tttttcagtg accaagatga tatatggtta gacaataaac tggaagtgac
    48181 cttattggag gctcaaaaac atgaaatgac agctccttta ttggtttata cagacctcaa
    48241 agtggtaacc caacatttag ctatttgcca tgacagtatg attaagaccc aatctggtca
    48301 tgcaaacaca agcctacttc aagaattaac cgaaaatacc gtaacaggcg gcacaatgat
    48361 gattactcat gctctggctg aggaatggac cacttgtgac ggtttattga tgcatgactg
    48421 gtatttagct ttactagctt ctgctactgg gaaattagtt taccttgata ttccaacaga
    48481 attataccgt cagcacgatg ctaacgtgtt gggagctaga acttggtcta aacgcatgaa
    48541 aaattggtta accccccatc atttagtcaa caaatattgg tggttgatta cttcaagcca
    48601 aaaacaggct caattactat tagatttacc attaaaacca aatgaccatg aattggtaac
    48661 ggcctatgtt tctttattgg atatgccttt taccaaacgc ttagctacct tgaaaaggta
    48721 cggttttaga aaaaatcgca tctttcacac ctttattttt cgtagtttag ttgttacctt
    48781 atttggttac aggagaaagt aagaatgaat tttttaacaa agaaaaaccg tattttactg
    48841 agagaaatgg taaaaacgga ttttaaatta cgctatcaag ggagcgcaat tggctatcta
    48901 tggtctatct taaaaccgct tatgatgttt acgattatgt acttggtatt tattcgtttt
    48961 cttcgcctgg gtggaaatgt acctcatttt ccagtagcgc ttttattggc aaatgtcatc
    49021 tggtcttttt tttcagaagc aactagcatg ggaatggtat ctattgtatc tcggggagac
    49081 ttgttgcgaa aattgaactt ttctaagcac atcattgttt tttcggcagt gttaggagct
    49141 ttaattaatt ttcttattaa tttggttgtt gttttaattt ttgcgttgat aaatggtgtg
    49201 actatatcag ggtatgctta tctctctctt tttcttttta tagaattagt tgttttagtg
    49261 cttggaattg cattgttatt gtcgaatgtc tttgtttatt atcgtgactt agctcaagtc
    49321 tgggaagtac tattacaagc aggtatgtat gccactccaa tcatttatcc gatcactttt
    49381 gttttagata gccacccttt ggcggcaaag ttgttgatgc taaatccagt agcacaaatg
    49441 attcaagatt ttcgttattt attgattgac agagccaacg taacgatttg gcagatgtca
    49501 accaattggt tttacgttgt tattccatat ttagtaccat ttgttatatt atttattggc
    49561 atctttgtct ttaagaaaaa tgccgataga tttgcggaga ttatttaatg attaatagag
    49621 aaattgcagt aaaagtacag catgttagta aaacatttaa actgcctaca gaagcaacta
    49681 aaagttttcg cacgactctg gttaatcgcc taagagggat taaaggattt actgaacaac
    49741 atgtgctaaa agatattaac tttgatgttt ataaaggcga tttttttgga attgttgggc
    49801 gtaacggctc gggaaaatca acgctcctta aaattatttc ccagatctat gttccagaaa
    49861 aaggacaggt tacagtagat gggaagatgg tttcttttat agagcttgga gtgggattca
    49921 atccagaatt aacaggacga gaaaacgtct atatgaacgg cgccatgctg ggatttacca
    49981 aagacgaagt tgatgatatg tacaatgata ttgttgattt tgcagagttg catcatttta
    50041 tgaatcaaaa attaaaaaat tattcttctg gcatgcaggt acgtttagca ttttcagtgg
    50101 ctattaaagc ccaaggtgac gttcttattt tagatgaggt gcttgctgta ggagatgaag
    50161 cttttcagcg aaaatgtaat gattatttta tggaaagaaa agacagtggt aagacgacta
    50221 ttttagtgac acatgatatg ggagctgtta agaagtattg taaccgtgca gttcttattg
    50281 aagatggtct tgttaaagca tatggagaac catttgatgt tgctaatcag tatagtgtag
    50341 ataatacaga gacagctgag gatgcaatga atgctgaaaa aatatctgta tctgatattg
    50401 ccaaagattt gaaagtgtca ttaatctcaa atccaagaat aacaccaaat gacacaatca
    50461 catttgaagt ttcttatgaa gttttaaaag atgattttac ctacattgcc ttttctttaa
    50521 cggatattga tagaaacatt tgggtttaca acgacaattc tttagattat ccaacacaag
    50581 gtataggtag aaaatgcatt tcctaccaat gtcaactatc tcaacttaat gatataaaac
    50641 taaaattaga agtaactgtc cgagataaga acggtcagat gctactcttt tcaacagcag
    50701 aacaatcacc ccagatagtg attcaaagaa acgatattga tcaagatgat ctgtcagctc
    50761 tagattcagc aagtggcttg tatcaacgta atgggaagtg ggtttttcat taatgagtaa
    50821 tagctagaag ggaatttatg tataaagttt caattatttg caccaattat aacaaagctc
    50881 cttggatatc tgatgcactt gacagttttt taagccaagt gacagatttt gaggttgaaa
    50941 ttattgttat tgatgatgct tctacagatg actcacgaga gattttaaag agttatcaaa
    51001 aaaagtcttc aggaaaaatt aaattactct ttaacgaaac taatattgga ataacaaaga
    51061 cttggataaa agcatgcctt tatgcaaaag gcaaatatat tgctagatgt gatggtgatg
    51121 attactggac ggatagtttt aaactccaaa aacaagttga tgtcttagaa gcttccaaac
    51181 ggtcacgatg gtgtaatact gattttgact ttgtaaatag tcaaggcgac ttattatatg
    51241 ctaatgcttt ttcatctggt catacacctt tgacagatac ttacgaaaaa gttttagcct
    51301 taaaagggat gacgatggca tcgacatggt tagttgatgc tgatttaatg agacaagtaa
    51361 accaaaaaat caatgtagat acaccagacg atacttttga cattcaacta gagttatttc
    51421 aactgactca actgacctat attaaagact caacgacggt ttatcgcatg acaaccgatt
    51481 ctgattcaag acctactgat acaccaaaaa tgattcatcg tattcaaaaa ctacttgata
    51541 ctcagttaaa ttacttaaaa aagtataatc aggtagatac aaaagaaatg tctgaactat
    51601 tattacaaca agatgctaag caagaaatac gaattcatga gttgagttgc tttattcaag
    51661 aattacaaca aactatcgta gataaaacaa agcagcaaga aacacgtgaa gtggagttgc
    51721 aaaatgtcat agaagaacaa aaaaatcaac tatctgaatt aagacaacaa taccatgcca
    51781 ttattaattc acgtcaatgg aaatacacgt ctaagctcat tgcttttatt aggagaaaaa
    51841 aatgaatcgt attttattat atgttcactt caacaaatac aataaaataa gtgcacatgt
    51901 ttactatcaa ttggaacaaa tgagatcact gttttctaag attgttttta tctcaaatag
    51961 taaagtgagt catgaagatt taaaacgtct caaaaaccac tgtcttattg atgagttttt
    52021 gcaacgcaaa aataaaggtt ttgatttttc tgcatggcac gatggcttga ttactatggg
    52081 atttgacaag ttggaagagt ttgactcatt gacgattatg aacgatactt gttttggtcc
    52141 tatttgggag atgggtcctt attttgaaaa ttttgaagaa aaagaggcaa ttgacttttg
    52201 gggaattact aataatagag gtacaaaagc ttttaaagaa catgtccaaa gttattttat
    52261 gacgtttaaa aatcaagtca ttcaaaacaa agtttttcaa caattttggc aatcgataat
    52321 agaatatgaa aacgttcaag aagtgattca gcattatgaa acgcaattaa catccattct
    52381 cttaaatgaa ggctttagtt atcagacggt ctttgatact agaaaagctg agtcgtcatt
    52441 catgccacat ccggattttt catattataa tccaacagca attctaaaac accatgtgcc
    52501 ttttataaaa gtaaaagcta ttgatgctaa ccagcatatc gctccttact tactgaatct
    52561 gatacgagaa acaaccaatt atcctataga tcttattgtt tcacatatgt cgcaaatctc
    52621 tttgccagat gctaagtacc ttttatctca aaaataccta aactgccaac ggttagcaaa
    52681 acaaacttgt caaaaggtag ctgttcattt acatgttttt tacgttgatt tgctagatga
    52741 atttttaaca gctttcgaag actggaactt ccattatgat ctttttatta caacagatag
    52801 tgatatcaaa agaaaagaga tcaaagaaat acttcaaaga aaaggtaaaa ctgctgatat
    52861 acgcgttacg ggaaatagag gaagagatat ttatccaatg ttattactaa aagataaact
    52921 ttctcaatat gattatattg gtcatttcca tacgaaaaaa tcaaaagaag ctgatttttg
    52981 ggcaggagaa tcttggcgaa aagaattgat tgatatgctc gtgaaaccag cagatagtat
    53041 tcttagcgtt tttgagacag atgatattgg tattataatc gcagatattc caagtttttt
    53101 tagatttaat aagattgtca atgcttggaa tgagcattta atcgctcaag aaatgatgtc
    53161 tttgtggaga aaaatggatg ttaaaaaaca aattgatttt caagctatgg atacatttgt
    53221 tatgagttat ggaacatttg tatggtttaa atacgatgct ctaaaatcac tttttgattt
    53281 agaattaact caaaatgata ttccaagtga acctttacca caaaactcta tattacatgc
    53341 gattgagcgg ttatttgtct atatagcgtg ggggaattct tatgatttta ggattgttaa
    53401 aaatccctat gagttaacac cttttattga caataaactg ttaaatttac gtgaagatga
    53461 aggagctcat acctacgtta actttaatca aatgggcggt atcaaaggag cattaaaata
    53521 tattatcgtt ggtcccgcta aagcaatgaa gtatatattc ttgcgtttaa tggagaaact
    53581 taaatgatta aagacacatt tttaaaaacc aattggttaa atattagtca ccatattatc
    53641 cttcttgttt tcggttttta tttcagtttt tacagtttgg cgaaagaact agtaagctcc
    53701 acggcacaac cggtaaacta ttatgctcat ttactaaatg tttcttttgt gggatatatt
    53761 atatcactga ttggattatc ttattatttg agtcgccaag ttagtcgaca gttgtttttg
    53821 aaaactagtt ttattgtgat atcttatcta attgtcagct attgggtaca aataacacag
    53881 cacctgaatg ataaacggtt tgatatctgg tcattaacta aaaatcaatt ttatcaattt
    53941 caagctctac cttctttact cattatttta gtgatggcca ctttaataaa aatattggta
    54001 gcatattttg caatagaaaa agatagattt gggctattag gctatcaagg taatactttt
    54061 tctgtagctc tgattttagc agttgtgcca attaatgaca tacatctgtt aaaactaata
    54121 agttctcgat tttctgaatt agtaagagca ggtaatagcc aaattgcact gttaaaaata
    54181 agtggactgt tgatagtttt acttgtcata tttgcaacaa tcatatacgt ggttttaaat
    54241 gctctaaaac accttaagtc aaataaacct tcattttcag tagcagctac tactagtttg
    54301 tttttagcat tagtttttaa ctatacgttt cagtatggcg taaaaggtga tgaagcattg
    54361 ctaggatatt atgttttccc tggagctact ctttttcaga tagtagctat tacactagtt
    54421 gctcttttag catacgtgat aacgaataga tattggccaa ctaccttctt tttgcttatt
    54481 ctgggaacaa ttatttctgt tgttaatgat ttaaaagaat caatgagaag cgagccgtta
    54541 ttagtaactg attttgtttg gttacaagaa ttaggtttag tgacaagctt tgttaaaaaa
    54601 tcggtgattg tagaaatggt tgtaggactt gctatttgta ttgtggtagc ttggtatcta
    54661 catggccgag ttttagcagg gaaattattt atgagccctg tcaaacgggc aagtgctgta
    54721 ttaggtttat ttattgtatc ttgtagtatg ttaataccat tttcttatga aaaagaaggt
    54781 aaaatattat ctggtcttcc gattatttcg gctttaaata atgataatga tataaactgg
    54841 ttaggttttt caacaaatgc taggtacaaa tctttagcat atgtttggac aagacaggtg
    54901 accaagaaaa taatggaaaa accgacaaat tatagccaag aaacaatagc gagtatcgct
    54961 cagaagtacc aaaaattagc agaagatatt aataaagaca gaaaaaataa tattgctgac
    55021 caaacggtta tttatctttt aagtgaaagt ttgtcagatc ctgatagagt atcaaatgtt
    55081 actgttagcc acgatgtttt acctaatatc aaggcaatca aaaatagcac aactgcggga
    55141 ctcatgcagt cagactccta cgggggtgga actgctaaca tggagtttca aacgttaaca
    55201 agcttacctt tttataattt ttcttcttca gtatctgttc tttattcaga agtctttcct
    55261 aaaatggcca aacctcatac gattagtgag ttttaccaag gaaaaaatcg tattgcgatg
    55321 catcctgcta gtgctaacaa ttttaataga aaaacagttt atagtaattt aggtttttcc
    55381 aaattcttag ctctatcggg ttctaaggat aagtttaaga acattgaaaa tgtcggttta
    55441 ttgactagcg ataaaactgt ctataataat attttatctt taattaatcc tagtgaaagc
    55501 caatttttct cagttattac aatgcaaaat catattcctt ggtcatccga ttatcctgaa
    55561 gaaattgttg ctgaaggaaa aaatttcacg gaagaagaaa atcacaacct aacaagttat
    55621 gctcggttat tatcgtttac tgataaggaa acaagagcat ttttagaaaa attaacacaa
    55681 attaacaagc ctatcacagt ggtgttttac ggagatcatt tacccggttt atatcctgat
    55741 agtgctttta acaagcatat tgaaaataaa taccttactg attattttat ttggagtaat
    55801 ggtactaacg agaaaaaaaa tcatccgctt atcaactcaa gtgattttac tgcagcttta
    55861 tttgagcata ctgattcaaa agtatcacct tactatgctt tgttaacaga ggtactgaat
    55921 aaagctagtg tcgataaatc accagatagt cctgaagtta aagctattca gaatgattta
    55981 aaaaatatcc aatacgatgt gactatagga aaaggttacc ttttgaaaca caaaactttt
    56041 tttaagatat cacgttaaga aaaatgctag gctgtccgag tatagacgag catcaaggtt
    56101 tggtaatttg ctcaaatgat tgtcaacaga gtgtctagga ccaggtttaa aagattataa
    56161 ttcttaaggt cttattcgtt tataaaaaat gaatactctt ttaaaatctt aattgaaatg
    56221 aataggagaa gttttcgtga aaaagttaat cattattcct gcttacaatg aaagcagtaa
    56281 tattgtcaat actatacgta ctattgaatc agatgccccg gattttgact atatcattat
    56341 tgatgattgc tcaacggata atacgttagc aatatgtcaa aaacaggggt tcaatgttat
    56401 ttctttgccc attaacctgg gaattggcgg tgcggtgcaa actggctatc gttatgcaca
    56461 aagatgtgga tatgacgttg cagttcaagt agatggagat ggtcagcaca atccatgcta
    56521 tttggaaaaa atggttgagg tattagttca atcttcagta aatatggtaa ttggatcacg
    56581 atttatcaca aaagaagggt ttcagtcatc atttgctcga cgtatcggca taaagtattt
    56641 tacttggctt attgcgctac taacaggaaa aaaaataaca gatgcaacgt caggtctaag
    56701 gttaattgac cgttcattga ttgaacgttt tgctaatcat tatccagatg attatcctga
    56761 acctgaaaca gttgttgatg tattggttag tcattttaaa gtgaaagaaa ttcctgttgt
    56821 aatgaatgag cgacaaggcg gtgtgtcatc tatctcgttg acgaaatcgg tctattatat
    56881 gattaaagtg actttagcta ttttagttgt tagattgaaa ggaaatcgtt aaaatgacgg
    56941 taacagccag tttatttata agttttattg tattaacctt tgttttcttt ttgattaact
    57001 taatcaaaaa agataaacta gcgattaagt actctttatt gtggtttatt ttagctttat
    57061 taattttact atttacgtgg ttacctaaca tattaaataa aatgtctcac ttcctgggta
    57121 ttcattcacc aaccaatatg ttattctttt taggtttttg tttgagttta gctattattt
    57181 tttcactgac taataatatt tcacttcaaa atgataaagt aaaacgtctg acccaagaag
    57241 tggcccttat gaaaaaagag aaaaccaatg attaatcctt caaaacaaaa ccaaacgatt
    57301 tttttatgga atatgttagg aagtttatca acagctgtaa tatcagttat attacttatg
    57361 gtggttacta ggttactaac ttcggctgat tcagatattt acgcctttgc ctattctttt
    57421 gctaatatga tggtagttgt tggacttttt caggttcgta attatcaagc aacagatatt
    57481 aatgaaaaat attcctttag tcagtactta gtggcaagac tgatgacttg tttattaatg
    57541 ttagccataa cagtaattta tttaacgtta actaagacag atagctacaa gagtacaatt
    57601 gtctttctag tctgtttcta tagatcgaca gatgcttttt cggatttata tcagggaatg
    57661 ttccaacaac atgaacggct ggatattgca ggtaaatcgc tagcctacag aaatactctt
    57721 atttttatgg tgtacacagc aataatatta tattccaaaa atcttacttt agcattagta
    57781 gctg
//
LOCUS       DATWVB010000010        52029 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.010, whole genome shotgun sequence.
ACCESSION   DATWVB010000010 DATWVB010000000
VERSION     DATWVB010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52029
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.010"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            100..333
                     /locus_tag="VCX65_000641"
                     /pseudo
     CDS             100..333
                     /locus_tag="VCX65_000641"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
     gene            361..588
                     /locus_tag="VCX65_000642"
                     /pseudo
     CDS             361..588
                     /locus_tag="VCX65_000642"
                     /inference="COORDINATES: protein motif:HMM:NF025063.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            715..870
                     /locus_tag="VCX65_000643"
                     /pseudo
     CDS             715..870
                     /locus_tag="VCX65_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039767.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(917..1447)
                     /locus_tag="VCX65_000644"
     CDS             complement(917..1447)
                     /locus_tag="VCX65_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HEP5053120.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(1440..2774)
                     /locus_tag="VCX65_000645"
     CDS             complement(1440..2774)
                     /locus_tag="VCX65_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HEP5053121.1"
                     /translation="MKKYLNQNVYDALIERLHFLFNEFPIVYISFSGGKDSGLLLNIL
                     LDFRDKYYPDREIGVFHQDFEAQYSLTTKYVQETFTSLEGRKKVSLYWVCLPMATRTA
                     LSSYEMFWYPWDDKTEDIWVRPMPSQDYVINLENNSITTYRYKMNQEDLAKQFGRWYK
                     QIHGNQKTVCILGNRASESLHRYSGFINKKYGYQKECWITKQFKDVWTASPLYDWSVE
                     DIWHAYYKFSYSYNELYDLFYKAGLKPSQMRVASPFQDYAVDSLNLYRIIDQETWVKL
                     LGRVQGVNFSNIYGRTKAMGYKSIALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKS
                     IDFWHKTGGGLAEETINELIEKGYRIARNGISNYTSFKHSRVIFLDQIPDDTDDIVTT
                     KDIPSWKRMCFCILKNDHICRTMGFGLTREQQKIVAFLKEKYKTSLKELESE"
     gene            complement(2996..3295)
                     /locus_tag="VCX65_000646"
     CDS             complement(2996..3295)
                     /locus_tag="VCX65_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053122.1"
                     /translation="MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEI
                     INFDDLRLTMVDMVSLSSEYDVIVTDMILEQTMDSEILFFNQMAPSVVANRLTDM"
     gene            complement(3452..3919)
                     /gene="perR"
                     /locus_tag="VCX65_000647"
     CDS             complement(3452..3919)
                     /gene="perR"
                     /locus_tag="VCX65_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEP5053123.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQSDF"
     gene            complement(3971..4426)
                     /locus_tag="VCX65_000648"
     CDS             complement(3971..4426)
                     /locus_tag="VCX65_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEP5053124.1"
                     /translation="MIYSFQNPSEDILKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEVQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNL"
     gene            complement(4613..7255)
                     /gene="polA"
                     /locus_tag="VCX65_000649"
     CDS             complement(4613..7255)
                     /gene="polA"
                     /locus_tag="VCX65_000649"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEP5053125.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPEEFREQFPYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKASKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAAISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     CEAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQAKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            complement(7386..9113)
                     /locus_tag="VCX65_000650"
     CDS             complement(7386..9113)
                     /locus_tag="VCX65_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEP5053126.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGVFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADVGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAVFLIAALGRGIMAMTSGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAQKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     QSKVSSWTK"
     gene            complement(9129..10325)
                     /locus_tag="VCX65_000651"
     CDS             complement(9129..10325)
                     /locus_tag="VCX65_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEP5053127.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVPKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            complement(10812..11903)
                     /gene="ulaG"
                     /locus_tag="VCX65_000652"
     CDS             complement(10812..11903)
                     /gene="ulaG"
                     /locus_tag="VCX65_000652"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEP5053128.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(12156..13802)
                     /locus_tag="VCX65_000653"
     CDS             complement(12156..13802)
                     /locus_tag="VCX65_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEP5053129.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INKALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            complement(14127..14831)
                     /locus_tag="VCX65_000654"
     CDS             complement(14127..14831)
                     /locus_tag="VCX65_000654"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEP5053130.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVAKMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            complement(14833..15696)
                     /locus_tag="VCX65_000655"
     CDS             complement(14833..15696)
                     /locus_tag="VCX65_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEP5053131.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDPATEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLA"
     gene            complement(15701..16363)
                     /locus_tag="VCX65_000656"
     CDS             complement(15701..16363)
                     /locus_tag="VCX65_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEP5053132.1"
                     /translation="MTHIPNLQVALDHSDLQGAVKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     IKEERGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIKRI
                     WG"
     gene            complement(16470..16955)
                     /locus_tag="VCX65_000657"
     CDS             complement(16470..16955)
                     /locus_tag="VCX65_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP5053133.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVQLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALITLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKNSPYLEGLDLD
                     A"
     gene            complement(17078..17356)
                     /locus_tag="VCX65_000658"
     CDS             complement(17078..17356)
                     /locus_tag="VCX65_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP5053134.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            complement(17427..18860)
                     /locus_tag="VCX65_000659"
     CDS             complement(17427..18860)
                     /locus_tag="VCX65_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEP5053135.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPIFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSNVELIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            complement(19167..21668)
                     /locus_tag="VCX65_000660"
     CDS             complement(19167..21668)
                     /locus_tag="VCX65_000660"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEP5053136.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGNEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIISVLEGGNVEEAAFTEDGLHINSGFLDGLDKASA
                     IAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDKSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEITGKDIIKVIAVPNKLVNIVIK"
     gene            complement(21879..23018)
                     /locus_tag="VCX65_000661"
     CDS             complement(21879..23018)
                     /locus_tag="VCX65_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEP5053137.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELVQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHPNHDTHLQQAKNGGAVLSFELASKEELMIFTHRIQLPILAVSLGGVESILSHP
                     ATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF"
     gene            23502..23780
                     /locus_tag="VCX65_000662"
     CDS             23502..23780
                     /locus_tag="VCX65_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053138.1"
                     /translation="MKNKLFLVALATVTVLGPSLATPHHRTVHATEQTVTQRTATETC
                     TLNGKICYGYENPDEDYTDSMVQSKSQDQGFFSWLWTQITTWFSSLMS"
     gene            23923..24153
                     /locus_tag="VCX65_000663"
     CDS             23923..24153
                     /locus_tag="VCX65_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053139.1"
                     /translation="MKKKLSLFMIATAAVVGLSLATPENQTVSANAQTPAVQNCENGC
                     CDRPFFGYCGPFSWLYYNTRYFLGYSDTATNQ"
     gene            complement(24437..24814)
                     /locus_tag="VCX65_000664"
     CDS             complement(24437..24814)
                     /locus_tag="VCX65_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053140.1"
                     /translation="MKQQSYKPLHFVYLLMALLTAMLLIARPVMADEEDKDPWRLGYN
                     QDLTKGKEDGKVAEWTDLTPPDPEVPKSPKDIDDSNHEHYRDGYKDGYKEGYNEGFGG
                     SYPLLLPVKFIWGLILHWWEKLI"
     gene            complement(25065..26780)
                     /gene="slo"
                     /locus_tag="VCX65_000665"
     CDS             complement(25065..26780)
                     /gene="slo"
                     /locus_tag="VCX65_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HEP5053141.1"
                     /translation="MSNKKIFKKYSRVAGLLTAALIVGNLVTANADSNKQNTANTETT
                     TTNEQPKPESSELTTEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDNKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKELQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRS
                     EYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            complement(26804..27289)
                     /locus_tag="VCX65_000666"
     CDS             complement(26804..27289)
                     /locus_tag="VCX65_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HEP5053142.1"
                     /translation="MYKVPKGLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITKRDSYM
                     GDISDPEVILEYGIYPAFIKGYTQLKANIEEALLKMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSILANITKALKDAHIREAMAHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            complement(27294..28637)
                     /gene="nga"
                     /locus_tag="VCX65_000667"
     CDS             complement(27294..28637)
                     /gene="nga"
                     /locus_tag="VCX65_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HEP5053143.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANNTTYAVSGKEGK
                     KSDVKYEMTKVMEANATSSKEDKHVMHTLDGSMSTVWEENSPGGGIGEVLSYKFASPM
                     HIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNMERDIFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAVQMSAVASRAEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRK"
     gene            complement(29005..29544)
                     /gene="nusG"
                     /locus_tag="VCX65_000668"
     CDS             complement(29005..29544)
                     /gene="nusG"
                     /locus_tag="VCX65_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEP5053144.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            complement(29717..30760)
                     /locus_tag="VCX65_000669"
     CDS             complement(29717..30760)
                     /locus_tag="VCX65_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEP5053145.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSAKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIEAAK
                     KAIIEGTITVPEN"
     gene            complement(31087..32379)
                     /locus_tag="VCX65_000670"
     CDS             complement(31087..32379)
                     /locus_tag="VCX65_000670"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEP5053146.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGERIDHYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            32817..33695
                     /locus_tag="VCX65_000671"
     CDS             32817..33695
                     /locus_tag="VCX65_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053147.1"
                     /translation="MIRKYDRTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKVAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPKIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHEANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDENLDETLRRLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            33708..34970
                     /locus_tag="VCX65_000672"
     CDS             33708..34970
                     /locus_tag="VCX65_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEP5053148.1"
                     /translation="MADFNFDIDQIADNAVVKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITARAPALVDTFLADQNALLDFGQSAVEGVNATVNHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSATPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIINANNAALQMLAETSKEAIPA
                     LEQSAQNPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKTTRA"
     gene            complement(35090..35716)
                     /locus_tag="VCX65_000673"
     CDS             complement(35090..35716)
                     /locus_tag="VCX65_000673"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEP5053149.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDL
                     IRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLKETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(35761..37176)
                     /locus_tag="VCX65_000674"
     CDS             complement(35761..37176)
                     /locus_tag="VCX65_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEP5053150.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            complement(37177..38952)
                     /locus_tag="VCX65_000675"
     CDS             complement(37177..38952)
                     /locus_tag="VCX65_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEP5053151.1"
                     /translation="MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKFIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQ
                     QSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFD
                     SVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFNEIMEGTAQVRDRIARSKFIPEE
                     NLEQIKGLTQKVTKEIHHVLAKGGI"
     gene            complement(39153..39473)
                     /locus_tag="VCX65_000676"
     CDS             complement(39153..39473)
                     /locus_tag="VCX65_000676"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEP5053152.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEALTHYDNQVLPAVIPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            complement(39470..40468)
                     /locus_tag="VCX65_000677"
     CDS             complement(39470..40468)
                     /locus_tag="VCX65_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEP5053153.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKERVIERMRPIA"
     gene            complement(40484..41068)
                     /locus_tag="VCX65_000678"
     CDS             complement(40484..41068)
                     /locus_tag="VCX65_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEP5053154.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKAFEQQFQVAQQQLKNQERQALLALKQDSIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            complement(41137..41616)
                     /locus_tag="VCX65_000679"
     CDS             complement(41137..41616)
                     /locus_tag="VCX65_000679"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEP5053155.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            complement(41618..43618)
                     /locus_tag="VCX65_000680"
     CDS             complement(41618..43618)
                     /locus_tag="VCX65_000680"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEP5053156.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEERHRQQAAQTALKMMSQKIERLEQLQNKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANDHFYHQLKKHKGLFIEEVYHTEFEYGLVLFWQ
                     AQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQSQKILAQL
                     QVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGDMFYLDSY
                     DVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTFFGMMVAD
                     LGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVALWGLIYGSFFGFDLPVALL
                     STKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFILLGLLLF
                     ILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGISSYLSDL
                     VSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLSMLSGYVH
                     GARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            complement(43608..43928)
                     /locus_tag="VCX65_000681"
     CDS             complement(43608..43928)
                     /locus_tag="VCX65_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053157.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            complement(44382..45401)
                     /locus_tag="VCX65_000682"
     CDS             complement(44382..45401)
                     /locus_tag="VCX65_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEP5053158.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            complement(45438..45803)
                     /locus_tag="VCX65_000683"
     CDS             complement(45438..45803)
                     /locus_tag="VCX65_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEP5053159.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            45977..46657
                     /locus_tag="VCX65_000684"
     CDS             45977..46657
                     /locus_tag="VCX65_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP5053160.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            complement(46778..47425)
                     /locus_tag="VCX65_000685"
     CDS             complement(46778..47425)
                     /locus_tag="VCX65_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEP5053161.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(47428..48087)
                     /locus_tag="VCX65_000686"
     CDS             complement(47428..48087)
                     /locus_tag="VCX65_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEP5053162.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVTLIFANKA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQVREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            complement(48099..49283)
                     /locus_tag="VCX65_000687"
     CDS             complement(48099..49283)
                     /locus_tag="VCX65_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEP5053163.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            49404..50315
                     /locus_tag="VCX65_000688"
     CDS             49404..50315
                     /locus_tag="VCX65_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP5053164.1"
                     /translation="MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEE
                     GVVLFQRQKGRLVGLTSVGERFFENAKVVIASHEQLMADLRSESKKYKGEISIGIPQL
                     ISGIVFSELIPKLIEENPEAKFHIVETGAYELQKKLFLKEVDFAILLTPTTLDATIAD
                     IDILLRDQLCLYMSHKTFQETFDSNPNISIKALHRQNLVTFDKTFMINHQLTTLFEEA
                     NSLPVVKCYSASWDFLLNCTRYSSYLTILPRPITHFAHMDGLVEVQLTEHPKWEVVLA
                     SLKHNKTSHLKHYIKHTILDYFMNQRF"
     gene            complement(50385..51791)
                     /locus_tag="VCX65_000689"
     CDS             complement(50385..51791)
                     /locus_tag="VCX65_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
                     /protein_id="HEP5053165.1"
                     /translation="MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLP
                     QTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LVPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFSVVGLSGLDLNSFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
BASE COUNT        15653 a        11226 c         9341 g        15809 t
ORIGIN      
        1 ctctatgcta aaggaagtcg atatcaatat aaatactata accgtcgacg ttcttcatga
       61 actcgtccca atcttgttaa tcaatgtttc caagcgactg ataagaataa attatggcta
      121 ggagacttaa cctacattcc tacacaagaa ggaatacttt atgtgtctgt cttgatagac
      181 gtttatagta gaaagattgt tggttgggca atgggccgac gtatgcaaga caagttggta
      241 acagaagctt tcaatcaagc ttataataga gaaaagccta aagaaggggt aatcgtccat
      301 acagatcagg gttctcaata taccggagca tgatttcagg acctacttag acagaaaaaa
      361 tgtaagtcca ggatgagtcg aaaaggtaat ccatacgata atgcactcat ggaatccttt
      421 tataaaacat taaaaagaga gcttgtcaat gatgctcatt tcgcaactat tgagcaagct
      481 cagcttgaga tttttaaata tagtgagact tactataacc ctaaacgtct gcattcagct
      541 ttagggtatc tctcacctgt agaatttgaa aaaatagtta ctcattagct taactttatg
      601 tctatttttt cttgacaagt ccagggtatg aagtcccctt atacacatac tttcaaaaca
      661 gctctcaatc ctctgtccgc tacaaaaata cgtcaccgct gccctccagc tgcctcattc
      721 aacgacaaac ttgaagccac aaacagactc atcaagggca ttaagtacaa tgcctttaga
      781 tttcagaact ttgacaactt taaaaccaaa atcctcatcg ctttgaacat ccaaaaagag
      841 agaaccaatc tgattctctc tcgttgttaa tgataagtca cccactacag ttgacaatga
      901 gtctcttact tcctgtttac tcatttaata gctcttctgg ttcccaagat tgattaaact
      961 catggtcctt aaaaagagaa gccaatcctg ttatttgttt cagtcttaaa atttcatctt
     1021 tatccattcc taaatgtttt gcaatccagt tatcacttcg cccacactca tgaagatcct
     1081 ttacaatctg actcatcaaa tcaacatcat gacttcctct agctctatta tgtcgaatgg
     1141 tagaagccat tcgatagtct aatgacttat caataacaga aacaggtaat ctcccacttt
     1201 ccctttcata aatatctgaa taatctagca ttatacgata tctatgaaaa ccatcaacaa
     1261 tactataccg atcctcttcc ttatcgtaat agcaaacaat cggcatagta taaccatcag
     1321 attttatact atcatacaat aatttcattt caggcggagc aactgaattc ggattataat
     1381 catttggaga aatcttttca attggaattg atttaatctc atagactgga ctaataaaat
     1441 tactcacttt ctaactcctt taaactcgtc ttatatttct cttttaaaaa ggctactatt
     1501 ttttgttgct ctcttgtcaa accaaacccc atagttcgac aaatatgatc gttttttaaa
     1561 atacagaaac acattcgttt ccagcttggt atatcctttg ttgttacaat atcgtctgta
     1621 tcatcaggaa tttgatctaa aaaaataacc cttgaatgtt taaaagaggt ataatttgaa
     1681 ataccatttc tagcaatacg atatcctttt tcaattagtt cattaattgt ttcctccgca
     1741 agtcctccgc ctgttttatg ccaaaagtct attgatttat taaattttct aacataatta
     1801 tttcttaacc tcactggtag cgttgataaa agaaactgag tgtacgactt ccacgaatga
     1861 ccctttggta aagcaattga tttatatccc attgctttag tacgtccata aatattcgaa
     1921 aagttaactc cttgaacacg tcccaaaagc tttacccaag tttcttgatc tattattcta
     1981 taaagattta ggctatcaac agcatagtct tgaaaaggag atgcaactct catttgtgat
     2041 ggttttaaac ccgctttata gaatagatca taaagttcgt tataagaata agaaaactta
     2101 tagtaagcat gccatatgtc ttccactgac caatcatata agggagatgc tgtccagaca
     2161 tctttgaatt gtttggtaat ccagcattcc ttttgataac catacttttt attgataaaa
     2221 ccactatatc tgtgtaagga ttctgaagca cggtttccta atatacaaac tgttttttga
     2281 tttccgtgaa tttgtttata ccacctacca aattgtttcg ctaaatcctc ctgattcatt
     2341 ttataacgat aagtagtaat tgaattattt tccaaattaa taacataatc ttgagatggc
     2401 attggtctta cccagatatc ttctgttttg tcatcccacg gataccaaaa catttcataa
     2461 ctactaagtg cagttctagt agccatcggt aagcacaccc aatacaaaga aacttttttt
     2521 ctaccttcta aagaagtgaa tgtttcttga acatattttg ttgttaaact gtactgtgct
     2581 tcaaaatctt gatgaaacac acctatttct ctatccggat aatatttatc tctaaaatcc
     2641 agtaaaatat taagaagtaa cccactatct tttccacctg agaaggaaat atagacaata
     2701 ggaaattcat taaacaaaaa atgtaatctt tctatcaatg catcataaac attttgattt
     2761 aaatactttt tcactaaact tcctcattat gcatttaaaa atattaatac atagattcac
     2821 taagaatctc tttttcgagc tttttgtttt ttaatttttc aagttgaata attaaacctt
     2881 gcttttcttt ttcaaggtaa tagactctac tccttgtaag tctaacttat tcttaatctt
     2941 atttatcgct cattttttaa attccgatgc tctcacagat attatcattg tttagttaca
     3001 tgtctgtcaa tctattcgcc accacactag gggccatctg attgaaaaat aaaatttcgg
     3061 agtccattgt ttgctcaaga atcatatctg tcacaattac gtcatactct gaagacagtg
     3121 acaccatatc aaccatggtc agcctcaagt catcaaagtt gataatctca aaaaatcctc
     3181 caaaatactc ttttaagaag ttgccaacat tgttataact tctctcaacc actaatagtt
     3241 tcaagcgacg acgcgattga tttgtaagaa agagattttc ccaggtgagg aacaaacaaa
     3301 tagaggagat gattgatggt tctttccttt aattccttat gatccccagc aaataactct
     3361 ttaacataag caacaaaggt ctggtattga actgggggtt tttgatttgt aaaggcacta
     3421 tatttataat gcctttattt aagggttaac tctaaaaatc agattggtct tttgcttggc
     3481 aatccggaca aatcccgtaa gcaataactg ggatacgcgt gaccttataa cctgtttgct
     3541 catgggcttc tttggcaata tccataacat caacatccat aaagtcagca atcttcccac
     3601 atatttcaca aaccacattg acgtgttgat ggcccataaa gtcatagtag gtggttaaat
     3661 cattgctgat tttcaactct gagacaaaac cttcatcaac taaaactttc aaattattat
     3721 agactgtggc aaggctcatg ttaggaaagt taggctgtaa gtcacggtaa atcttatcgg
     3781 cactagggtg ttctgtggac tgaatcatgt aagaaataat ggctttacgt gtctctgtaa
     3841 ttcgaatatg tttttcccgt agatgctcta ggacattttc ataggcatct agggcttgct
     3901 gatgtgaatg aatgtccata agctgctact cctatccttt tttcctttat tatcacgcac
     3961 gtctctagtt tcaaagattt gtgatgcatt ctggtttagc gactaattgc aaatagtcta
     4021 tttttaggca gcgattcatc acaatagcct ctttgcctgc cgaccgtaaa atggtttgta
     4081 cttcttggtt ttcaaggcct aattgcgccc aaaagacttt ggcctgacct gctaaaaagt
     4141 ctctggcaac ttctggtaaa aactcacttc tgcgaaagac atctacaatg tcaacctcaa
     4201 agggaattgc cttgatactg gcatagacct tctctcccaa aataagctga cctgctaatt
     4261 tgggattgac tggaatgatc cgataatcca tagcctgcat aaatttggcg acaccataag
     4321 ctgctgtgtc tttgcggtca gaaagaccaa caaccgcaat ggttttggct gactccaagt
     4381 aagcttttag gatatcctct gagggatttt gaaacgaata aatcacttgt tcccctatct
     4441 atttaataac ctctacagct gttcaatata gcaggataac tcctaaagca tggcttcaat
     4501 cacttttaac cttatccgtc aaaaagctca aagcagcttc atgacttctc ctacaatttt
     4561 ttagtttatt ataacataag ttgtcaaaat gagaaataac aagtaagaaa acttatttgg
     4621 cttcgtacca gctctgccca gtactttcat cgacacataa aggaacagct aaatcaacag
     4681 cagcttccat ggtgtctttg acaagttttt ttatagcagt caactcatca tttggcactt
     4741 ccaaaacgat ttcatcatgc acttgaagca gcattttagc tctaaaacca cctgcttgca
     4801 aggccttatc cagattaatc atagcgattt tgagaatatc agctgcgctt ccttgaatgg
     4861 gcgagttgat ggctgtacgc tccgcaaaag agcgaacgtt gaaattacga gagttgatat
     4921 ccggtaattc acgacgacgc ttaaagaggg tctctacata gcccttgtct ttagcctcac
     4981 gcaccacatt ttccatatag gctttaatcc caggatagcg ttcaaaatag gtatcaatgt
     5041 aagacttggc ctgtttacgg gtgataccaa ggttatttga caaaccaaaa tcagaaatcc
     5101 catacacaat tccaaagtta acagccttgg cattacggcg gtcattggca gtaacatctg
     5161 ctgccttgtc aatcccaaac acacgcatag ccgttgaggt atgaatgtct gccccttcat
     5221 taaaggcagc aatcaaatgc tcatcccctg aaatatgtgc cagtacccgc aattcaatct
     5281 gtgagtaatc tgaactcaac aagacggcat cttcatgaga tggggtaaag gccttacgaa
     5341 tcaaacgccc ctgttccaaa cgaatgggaa tgttttgaag attagggtcc acactagaca
     5401 aacgccctgt ctgggtgaga tcctgcacat agcgggtatg aatcttgcca tcagccagaa
     5461 tataatcctg taaaccaatc acataggtgg attgcaattt agtaatctgg cggtaatcca
     5521 aaattttagc cacaattgga gcaatcggtg ccaaacgttc caaaacatca acagctgtag
     5581 aataacctgt tttggtcttc ttagtcatct caagaggtag ttgcatcttc tcaaacaaga
     5641 tactgcccag ctgtttaggc gaattaatgt taaattcttg gccagccata tcataaatct
     5701 cttgggtgag cgcttcaata atgaccttgt tttgctctgc catatcttgc aaagtcgccc
     5761 tattaacctt gatcccttca atttccattt tagcaaggac attagccaaa ggcaattcaa
     5821 tattctgata gaggtctagt tgctcatggg cagtaagctt gtctagcatt tgagacttgc
     5881 tatctaataa tactttgacc ttacgagcta agtgttctag taaaacgtct ttatcaggaa
     5941 cagcccgttt agcaccttta ccatagactg tatcgtcttc ttccaaagag atgtcagtaa
     6001 aaatgcgggc aatggtgcta agctcattgt cttctacagt tgacagaagg taattagcta
     6061 atctagcatc atagctaggt gctaccaact caattcctaa gtggctcaac aagaccttgc
     6121 tacgtttaaa atcataagtg gcaatgggtt tttggaagac ctgcttaaaa ctatccgtcg
     6181 ctaataggct aaggtcagtg gatgcgtaaa tctgctcacc atgtccccaa gcaaaaccaa
     6241 tgatggcctc acaatggtaa ttatcccgaa gcgtttcaaa gtagaagatg tcttctgcgc
     6301 taaacaaatc agcagacaca ttggtcactt cttgatagga aatggcagct actggctctt
     6361 gaggcatctg gctagcaaga cctttcttga gttgcacaaa atccatctca tcgtaaaatt
     6421 gagagaggct agcaacatct ggaccattgt agacaatatc atctaagcca attgtgatag
     6481 gagatgctgt attgatagtg gcgagcgttt tagataggaa agcttggtca cggtcattga
     6541 tcaagttttc tttcattttt gaggccttga atccatcaat atgctcgtaa atgccttcca
     6601 aactaccaaa ttcatgaagg agcttgagcc cagttttttc accgattttg gtcactcctg
     6661 gaatattatc cgatttatct cccatcaagg ctttgaggtc aataaactgg tttggcgtca
     6721 agcccatttt ttccatgagg taagccggtg tgaattcttc aaattcggca accccttttt
     6781 tagaaatttc aaccacggta ttttcgtcag ttaactggat caaatcttta tcaccactga
     6841 caatggtcac atcaaaaggc acttctgtgc gctccgccat tttatcaagc gtcccgataa
     6901 tatcgtctgc ttcgtagtgt tccaactcat aataagcaat cccaagggct gtcaacatct
     6961 cacgaatata aggaaactgc tcacgaaatt cctctggtgt cttggcgcga cccgccttat
     7021 aatcggcata catttctgtt cggaaggtgg ttttgcccgc atcaaaagcc accagcacgt
     7081 gagtaggctg gactcttttc atcatgtggt ctagcatcaa atgaaagcca taaatggcat
     7141 tggtatgaag accgctatga tttttaaagc ggtcaatttg attgtagagg gcaaaaaagg
     7201 cacgaaaggc aacagatgag ccatcaatta atagtaattt attcttgttt tccatagcct
     7261 tattataaca cagagggacg ggcttttctc ctttaagcca ttggttttgc tgataagtaa
     7321 atagttaacc taaaaagcct aggaaaattc ctagacttct ctatttgcta tttagacaaa
     7381 agcacttatt ttgtccaact tgatacttta gattggtttg cctctaccca ttttttggcg
     7441 gcagcttctg ggctcatgcc tttgttgatg tcaagcatga ctgcttccat atctttttgg
     7501 gtccagtgga acttatcaat gattttgtag acatttggaa gatctttttt caagccttta
     7561 cgagcaatgg tattgatgtt ctcagtcgag ccaaaggttt ctttaggatc tttaaggtac
     7621 ttcaagtcat acttggcaaa catccagtgt ggtgaccaag ctgtcacgac aataggatct
     7681 tttttcttga tcgcttgatc caaggaagtc gtcatggctc ctgttgatgc cgccactaac
     7741 tcccaactag atagattatg atactctttt agagtctttt gggctgctgc catgatacct
     7801 gcacctggtt cgatccctgt gattttttga tcggcttgtt tgcttaagtc ctcaatacta
     7861 ttaacatctg tcatgtattt tggaacagct aaaccaagtt tggtcccttt taggttaggt
     7921 cctaaatcat ctaattttga cttgtatttc tgatattgtt ggccatgggt gactggcaac
     7981 caagcactag ttgaaaaatc agcgttccca tttgcaacgg tttgccacat aacggcattg
     8041 tcaagcggag tcaaggtcac atggtaacct tcgtttttca aaacttctgc aatcacatga
     8101 gttgaggcaa cctcagaatc ccactgcacg taagcgatgt taacagtttc acccttatct
     8161 gccataccag aagtcatagc cataataccg cgtcctaaag cagctatcaa aaagacagca
     8221 agggctgcta gaccaatcca tttattggtt ttgccagctt tggctttttc ttgaggtttg
     8281 ctattgaaca actgtgtcat acggtcaagc acaatcgcca agataaccaa ggcaagacca
     8341 ctgacaaatc cactaccaac atcagcgtgt tgaagggctg acaagacttc acgtcctaag
     8401 ccaggagcac caatcatgga gcctgttact accatggaaa gggctaacat catggtctga
     8461 ttaacacctg ccataatagt atttttagct aaaggcaatt ccactttaaa gagcttttgt
     8521 ttcccagttg acccaaaggc atctgaggcc tcaatcaatt ctgttggaat gtcacgaatg
     8581 gccaaatttg taaaacgaac cgttggaggc aaggcaaaga tgactgaggc aaacactcca
     8641 ggcaccatac caataccaaa aaaggcaacg gcaggaatca agtaaacaaa agccggcatg
     8701 gtttgcataa agtccaaaat aggattcaca atctgacgga cagtggcatt tttagccatc
     8761 caaatcccca gcggaatacc aataagtacc gaaatcaaac tagctactaa caccagagta
     8821 aaggtattca ttagctgctt ccataaccct tgattgtaaa taaagagcaa tcctaacaag
     8881 gtaaaggttg gcaaaggcca ttttttctta gcaaggaaaa acacccctgc tgttactaga
     8941 acaataaaaa gtaacgggtg gataaataaa agtgttttgg tcatccaatc catcaaaaag
     9001 ctaccaacta cttgcataat atcaaataga cctgagaaag ttttagttag ccactccgtt
     9061 agctgctcca ccagttgagc tactggtaat tttgtttgta atatcgtttc caaaatgcat
     9121 cactcctttt agttaaggtc ttcgtctgag atattagcca aggcttcaat cactcgtcct
     9181 cgaataatga cacctagcag acgattatta tcatctgtca ctgcaatcgg agcagatgaa
     9241 tcatagataa gaggcaaaat atctgtaata atagtatctt ttgagacagt tctcacatcg
     9301 cgatcaatca cttctgatag cggtaaccct tttttgcgcg cctctatagc ggcatcggcc
     9361 gtcaaactac cgactaattg gcggcggcga ttcgtcgcca tcaacataga cacctcttcg
     9421 ttgtgcatac ggttcaaggc aacttgaggt ccatctaatt caacagtagt tgttaacggt
     9481 ttgatcatga tattttgtgc tgtcaagact ttagaacggt ccacatcctc aacgaattca
     9541 cgcacaaagt cattggctgg gttagtcaag atttcctcac cagtaccaat ttgcataatt
     9601 tgtccgtctt tcatcaaagc aatccgatca ccaatacgca aagcttcatt caagtcatga
     9661 ctgataaaga tgatggtttg tttcatgctg tcttgcaaat caagtaattc atcttgcatc
     9721 tcacgacgaa tcaaaggatc aagcgctgag aatgcctcgt ccattaagag aattttaggg
     9781 ctattagcta gcgcacgggc taggccaaca cgctgctgca tcccaccaga tagttggttt
     9841 gggtactggt ctttaaaatc taataggcct gaattatcaa gggctttttc tgccaatcgc
     9901 tggcgttctt ctttgggaac gccacgtaat tccaaaccaa attcggtatt ttccaaaatg
     9961 gttttatgag gaaagagggc aaagctttgg aaaaccatgt taatgtcatg gcggcgcacc
    10021 tcacgcagct gatctgctga catggttgag atgtctttac cttccagcaa gatagatcct
    10081 gctgaaggtt caatcaaacg atttagcatg cggacaaggg ttgatttccc acttcctgat
    10141 agccccataa taacaaagat ttcacctttt ttgacctcaa aactagcgtc atagacacct
    10201 acagtagcgc ctgttttctt aaaaatctca ctcttatttt tgccagtctt taccatctca
    10261 agagctgctt tttgtttttt gccaaaaatt ttactgagat gtttgacttc taaaattgtt
    10321 tccattcgtt ttttctccta ggtaatcgtt tattatgtga aatagtgaca tagctttggc
    10381 gaaatattag ccaatattta acaaagtagc tctacacaat taataaacgt gtggtcactt
    10441 ttttacttaa aaaaagaatc tgccgaaaca gaacataact atattatcac gtgtggtcac
    10501 tttttgtcaa ggacaataac tcgatctgta ataccacaat gataggtgat cgctttcatt
    10561 cttttaggta tggtctttta accagtacaa ttttttatca caactgatga ctatttcttt
    10621 gctgattagg ctattgttac attagaaatc cttcttttac ctataatatc tcttttgcgg
    10681 ccatcgtaaa taacgaccac ggtgactctt aaacatttgc tcatctctcc aaaaaaactc
    10741 acctaagaca gtgtcctatg aagcgagtta gcttaatcag gcactatcat cttaggtgag
    10801 tagggtgttg cttatagtaa agctttaaat tggatattag aatcttctaa gaagcagtca
    10861 tcaaatccac gaggatgatg gtattcgata cgattttggt cttgtggata ggtgtacttg
    10921 ccaccaacct cccagataaa gggatggaaa tcgtattgga gacgttcttt gcgcattttc
    10981 cacagttcaa ggatttcatc tgttgatgcc ataaagtttg accaaatgtc ataatgaact
    11041 gggataacga ctttagcacg gagattttct gccatacgaa gaaggtcaac agaagtcatc
    11101 ttgtcttgaa tcccaattgg gttttcccca tagttattta acacaacgtc aatatcataa
    11161 tcacgtccat gtttagcaaa gtagttcgaa aaatgagaat ccgcaccatg atagatggta
    11221 ccacctggtg tttcaaaaat atagttaaca gctttgcgag ccatgtcatc atctgtgata
    11281 gctaaacctg ctaaatcacc atcttgagca tcagctcctt gtattgggag agttaccaga
    11341 caggtgcggt caaacgactc tacagcggtg atcttaatat ctttgaattc aaagctatca
    11401 cctggcttta agatcataat acgatctttt ggcacacccc aatttttcca aacttcacca
    11461 cattcataag gtcctacaaa tttaacatga ttaagttttg ggttattgat aatggctgcc
    11521 gcagtattga tatcgatgtg gtcactatga taatgagaaa ccaaataata atccaactca
    11581 ttaatcataa atggatcaat caccattggt tgggccctaa gattgggctg taatttacga
    11641 gctcctgcca tattagccat ttgatgtcca cgaaccatat ccttaacttg cttggtcgct
    11701 ttcccacgat ttgaccataa gtccatgaca acattagcac cgcctggtgt cttaatccag
    11761 ataccacagt ttcctaacca ccacatcgca aagttgtcag ctggcacgac ttcttgctcg
    11821 atttcttcat ttaaccatgt tccccattct ggaaacgtgt taaggatcca tgattcacgt
    11881 gtaatatctt gtactttagt cattagggtt tcctccgaat ttgttcttcg tttctatact
    11941 ttaagtatag actttcttgt caatgataaa aagaccaagt gtcacacaga tctgtgttca
    12001 aaagtggact gactttttca ttagctcagt ctaatactgt ctcattttgc acactgtatc
    12061 tcgcatcaat actgtattca aagctatatt aaaaacctca gttatatttt tctatgtcat
    12121 agaaaactga ggtactttga cgacttaaca cttactcata gcagctcgcg atgaatgagt
    12181 ttttcaattt tagaaaccaa ggcataacga tctgattcat cttttacaac agcttcaata
    12241 gcttttgtga gctctgtaga aaagcgggag tgctcactca agcgtccttg ctttgaaaag
    12301 cgtatcaatt tgatgatatc atcgtcactt aaaatagggt taacaataag catcgggatt
    12361 ttagtcttta gcgtatctgt agtagcaaca atcatatcga ctgctaaaag gtcgtaaaca
    12421 ctctgatact gttctgtcgt aaaaacagct tcaatctgac catttgctag atacctttga
    12481 cactgtttga acaataactt ttgaatgcct atcccatcat ctgaaacaat aacgagtttg
    12541 gtcttttctt gctctgtatt attgtgacgc agctctcccc caagatggat agtcaagtag
    12601 gcaatatcat cgtctgtcaa gctaatcgtc caatcttgtt ccaaaatagt ggcacaagat
    12661 tgagtcatag caaacaattc ttcgtatttt tctttaatat ggtctgttaa gggattaact
    12721 aaaaaaatcc cataagcttt acggtaaacg agcgccttac agtgggtcgt caactgcttc
    12781 agcaaatcct gtttatgcgt gaaatgtaac tgataacggc tctccaactg gtcaataaag
    12841 tgactaatgg ttgctcgcat gtcgtcataa tcttgacttt ccacgtgatg atcttgatct
    12901 tttcgaaaag acaacatcaa catcgctacc atactaactt cgatatcatc caaatgaagc
    12961 ttaaaattat ggtaaagctc tctagctaaa tcctgagcaa tgtgatattc tttacgtttc
    13021 caaatcaaat gaaattcttg tttaagagca gactttgttt ctgaatcaag acgcatatta
    13081 cgataactta aaagcatgaa aggtaaaatc tgcaacatga attggctatc ttgggtatta
    13141 attgtctttc ctaagctagc ttgagataaa aagagatact catgaaaata agtcaaaata
    13201 tctttagaaa aataaaccga taagccttgt atctctgaga gtttacggtt gaatatatca
    13261 ataaagctag tattgccacc ttggtaaacg tccactaaca atttgtacag gtattgaata
    13321 agagccattg gatgacaacc aaaataatat cccctagcct ttgtcgcatg aagctgaatc
    13381 ttgtattgtt tgtcttccag ttcttccctt aactcagtca ggtcatttaa aatcgtgtta
    13441 cgagacacat cattgatctg catcagttta tcaatggtca cgcgctcagt ggaaaccgca
    13501 atataaatcg aggataggcg tctgcgctca tcacttttca tgacataatt ataatcagtc
    13561 acttcttcta ataataagcg acaagcagct ttttgatcag ctgttaaaag aatgccaagt
    13621 ctaggataag agataatctg atctactccc tttggcaaag ccttattaat tttgtcaagc
    13681 tggtaataaa ctttacgacg tgactgattt aaagcatgag aaatggccat aactgtctca
    13741 ggtgtttcta gtttaagtaa ataagacagc aagtcataac tctttttatc taaaatcatc
    13801 atgattacaa acctcctctc tgaaaatcca tccttgctta ttttatcatg atttcagtga
    13861 ctgcgcagcc aagttttgaa aaactcacca taataagatt cgcttaatat gattcgagct
    13921 aatcacctca actgatccaa caccaacacc ttatatctgg tctctaagaa ctccacaaca
    13981 tacgattcat caagtttgtg ctcattggcg tttaaacagt tcatcgaaaa ggacaagtca
    14041 aaaggacttg cccaaacaat gattaacaaa accttgaact ttctggcttc tagtgagaac
    14101 ctgtgctaat aagccatatc gtgacctcat ttttgaccgt aataagcatt tgggccatgt
    14161 ttacgcaaat aatgcttatc cataatgtat cgtggcgctg gctctacgcg tggattgatt
    14221 tgttctgtca agcgattcat tttagccact tcttctaaga caaccgagtg gtaaacggct
    14281 tgctctgggg ttttccccca cgtaaatggg ccatgattgc gaaccacgat tcctggaacc
    14341 gccataggat ctaagcctcg cttgctaaac tcttctaaaa tcacgttgcc agtttcttgc
    14401 tcgtaagccc catcaacttc tgcttttgtg agagaacgag cacacggaac tggtccatag
    14461 aagtagtcag catgcgtagt cccataaaac ggaatatcac gacctgcctg agcccaacca
    14521 acagcttctg tggagtgagt gtggacaata ccgcccactt ctggccaagc tttataaagt
    14581 tccacatggg ttggcagatc tgaagaaggg ttcaaatcac cttcgaccac attcccatca
    14641 aggtctgtaa caaccatgtt ttctggtgtc aagaggtcgt agtccacccc agaaggcttg
    14701 atgacaatac gtcctaattc acgacaaact tcagagacat tgccccacgt aaatttgaca
    14761 agaccgtgtt gtggtagaga cttgttagcc gcacagacac gttcacgcat ttcttgcaag
    14821 tttttcgcca tattatgcca accccgcttt ctcaataagt gggtaaagga agtcctgagc
    14881 ttctttgata gcagcttttg tttcctccac cgtgtcacaa ttttctgacc acatttcaat
    14941 caaaaaaggc ccattgtagt tggttttctt gaggaccgca aacagctctt gccagtccac
    15001 acaaccttga ccaaatggca catcacggaa ctgccctttt gaggtttccg tgacagcata
    15061 agtatctttc aagtggagag ctgcaatgga cttgtgacca ttgtaaaatt cactccacaa
    15121 atcgttatgc caggcagaaa cattgcctgc atcaggataa acaaagagat aaggcgagtc
    15181 aatctctttt tcaactgcca agtatttttc aatagagttg ataaaagggt catccataat
    15241 ctcaatagaa agcatcactt gggcttcttc ggcccagtca caagattgtc tcaagttttt
    15301 gataaaacga gcacgggttt caggcgattt ttcttcatag taaacgtcat aaccagctaa
    15361 ttgaatggta cgaacgccta agtcctgtgc caattcaata cattgtttca tcagtttaag
    15421 agacttggct tcagtagcag gatcatttga gcctagtggg taacgtctat gaccagaaaa
    15481 acaaatggtc gggatgcgaa tgcctgtttc ataaatggct ttcactaaat caagccgttc
    15541 ttccttagtc cactctaagc gcgctaagcg agcatctgat tcatcgacag acatctccac
    15601 aaaatcaaaa cctaagtctt ttgcaaattg caagcgttca cgccaggtaa actgttttgg
    15661 cgttgctttt tcataaatac caataggacg cgccataaag ttacccccag atacgtttga
    15721 tttcatcttt gaaggcacgc gccgctgcag caggatcttc tgcttcagta atgcctcgcc
    15781 ctgcgataaa ggtaaagaca tcaacccctt caaaaagttt caaagtgtct acatcaagcc
    15841 caccagttac tgagacacga aagcccatgt caatcaattt tttcaccttg ttaaggtctt
    15901 tttcacccca agtttctcca gcaagaaggg catcacgaga ttggtggtaa atcgcttggg
    15961 aaatcccagc gtcaagccat aattgagctt gctcataagt ccaatcacca taaagttcga
    16021 tttgaatttc cccacggtca ccgcgctctt ctttaatagc cttgagggct gcttccatgg
    16081 ttggaatcgt cgcacagcaa atgcaggtca tccagtcagc accacgtttt gcattgtttt
    16141 tagcgaccgt accgccagcg tcagcacatt tggtatctgc tacgataatt ttctctggga
    16201 agaggctgcg taatacctca actagttcgc ttcccacttg aagcaaacaa acggtaccag
    16261 cttcaatcac atctacttcg tgacccacag caacggctgc tttaacagcc ccctgtaagt
    16321 cagaatggtc taaagcaact tgtaaatttg gaatatgtgt catctctttt tcctaaaact
    16381 cttagccacc gtgcaaactg gttaagagtt cttatccttt caataatgat tgtgagtcgt
    16441 tttatccgtt taagtcagta agctatcgat taagcgtcta aatccaaacc ttctaaatac
    16501 gggctatttt ttgattcttc taccatttct agaacctctt taggactttg gcaggccacc
    16561 aagcgttcaa tggcgttatc tagttcaaac aaggccacaa tttgtgggat agccactgtt
    16621 gtgtgaatag aagggtctgt agcggccaac gtcaaaagaa cagaaacctc tttaccatct
    16681 gagaaggtga ctggttttgt tagtgtaatc aaagcaaatg cattgcgatt aacgcctaaa
    16741 cctgcttctg catggggcat agccatacct ggcatcaaca cataataagg gccgtatttt
    16801 tctgttgatg caatgatggc gtcgtagtaa gctgacgtca ctgctttgct atcaatcaaa
    16861 ggttgaacag ctaattgaac agcctcttgc caagtatcag cacttagccc caatcggatg
    16921 gagttgttgt caataaaggc ttgttttaaa ttcataaaaa ctatctcttt ctagtgtctt
    16981 gctttgcaac acacaccatt tttactagtt ttatcctact aaagagaaag agctgaaaac
    17041 cttcgtcaca actccttcgt tttgattcag aattagctta tagcacttct tgtagtttgg
    17101 ttttaatttc attatcatcc atcaggttat caagaccaac caagtgacct ttggtacgac
    17161 catcaagctc atgaatcaag tggtttgatg ccactacaat atcataacca gaagctagac
    17221 ctttagcttc accaactgag caagaagctg actgaatatc tgtcacacca agttgacgaa
    17281 gcgcattttc aactttcatt ttgatcacca tagatgaccc cataccattg ccacatgctg
    17341 ttaatacttt aaccattgtt ttttcctccg aaaatgtttt attattattt tgttagaata
    17401 gcagagctat ttcttaagat gcagtgttat tgagcttccc cacggtaata agcttctttg
    17461 tccttagctt ttgcgaattg caattgtgga atggcaagta agaagatgca aacaagcaca
    17521 taccctgcaa taccaaggaa tttgaagagg tacccaaatg gtaaccatgg aagaaccaag
    17581 tcgatattac cgtgataacc acctgtaagt cctaaaagac ctacagcaac agcaccaagt
    17641 gcaacttgca aaatacctga gataaatgat agagctaccg ctgctttcca gccaccacgt
    17701 ttatctgcat aaaccgcaat tgccgcatta tcaaagaata cgggaacgaa tcctgtgata
    17761 attaagattg gatttttaaa gataacaaga agagcaatgg tgattaattg accaatcaaa
    17821 ccaaaggcaa atcctgaaag caccgcattt gaagaaccaa agccatagga agctgcaacg
    17881 tcaaccgctg ggaatgaccc tggaagcaat ttgcttgaga tcccttgaaa ggcattggtc
    17941 aactcagaaa cgaacatacg tacaccttgc atcaaaatga agaggtaaac agagaaggtg
    18001 agtgatgttt gaagaatata catgaagaaa gcttgcttag ctgggttgaa agcgcctggt
    18061 ccgattaact ctacattaga catgatgtct ggaccaagga cagccaagat agctccaaag
    18121 aagactaaca ttaaggttgc tgacgcaaca acggtatcgt ggaaaatatt taagaaggtt
    18181 ggtaatttta agttatcaag gttttcttct tttttaccaa agattggagc aaccttatcc
    18241 acaaaccaaa tcgcaaattg ttgttggtga ccaatcgcaa agccaccgcc acctgttagg
    18301 cgttgtgttg cttcaaccgt catgtttgag ctgactgccc agtaaagacc acagatgata
    18361 ccaaccgccc aagcaccaaa agcattttgg aattgaggga ttaaaagaag gacaaagacc
    18421 gaaatcgtcg ctgcctgttg gaccatgatg tgacctgtga tgaaaagggt acgaacttta
    18481 gtgaccttgc gaagtgcaac caaaagaatg ttgaccccaa atccaatcaa gagagctgtc
    18541 gtagcaacac tgatgaagcc catctcttct aacttagtat tagcagcagc caaaccaaaa
    18601 taaggatcaa taacggcggc tttcaattca aatttcttgg caagagcaac caagatcgga
    18661 cgaaaagtcg ttacaagacc gcctgctcca acgttcaaaa tcaagtaacc aacggtagcc
    18721 tttacaaaac cagcaaagac ctcataaatg ggttttttaa ggagtaaata cccgattaaa
    18781 accaaaagac ctacaaagaa cgctgggttt tgcaaaatat tttgcgagaa ccagtttagg
    18841 ggagctagga gcatttccat aagaactacc tcttttcaaa gttaataaag ataaagtgtt
    18901 tatatgttca ttataggtaa tgaaagcgtt ttaaaaaaga ccaactatca cacaaagaag
    18961 tgttcaatat tagacttaag ttaacttatt ttaaaattta actacactta ataataagga
    19021 ggaaataccc ctaaacaacg attaaaaacc acaagaacct tcgttcttgt ggtttttcta
    19081 gataagttgc tttttgaata gatcagctct ttggcattaa ctgtgacgtg acgcaaataa
    19141 ccactgaagg gctgtgtcac ctcaaactat ttgataacaa tattaacgag tttgtttggt
    19201 actgcgatga ctttgatgat gtctttgcct gtgatttcgg cttggacttt ttcgttagca
    19261 agggcaactt cttgcaattc ttcgcgtgaa aggtctttag caacgacaag tttagctttg
    19321 accttacctt tgatttggac aacgatttcc acatcgtttt caaccaattt gcttttatca
    19381 taacttggcc atggcacgta agagattgac tcacctgagg ctgtcaaggc ttgccagagt
    19441 tcctcaccta agtgcggtgc aaatggtgca atcaattgaa caaagccttt ggcatagtcg
    19501 ctaaagagtt tgtcttcctt gttggctgcg ttgacaaaga ccatgagttg agcgatagct
    19561 gtgttgaatt tcatttggtc aacttgctca gtaacggcct taacggtttc gttgtaaacc
    19621 ttgtcaagag ctccgctatt ttcctcagtg atctctttag ttgtgatcaa acggtaaaca
    19681 cggtccaaga acttacgtga gccttcaaga ccttcttcag accaagcgat ggaagcgtca
    19741 agtggtccca tgaacatctc gtaaacacga agagtgtcag caccgtactg ttcaacaaca
    19801 tcatctgggt tgacaacgtt cttaagtgat ttagacatct tagctggtgc ttgttcaagc
    19861 tcttcaccag tttccacatg gaagaagctg ccatcacgtt tttcaacctt gtcagtcgct
    19921 acaagcgctc ctcggctgtc gcggtagctt gttcccaaaa tcatcccttg gttaaagagt
    19981 ttttggaatg gctctttggt tggtacgaca ccgagatcgt aaagaacctt gtgccagaag
    20041 cgagcgtaga gaaggtgaag cacggcatgc tctgcaccac cgacatagat atcaactggc
    20101 aaccattgtt tgaggagttc ctcgtcagcc agtttttcgg tgttgtgtgg atcgatgtaa
    20161 cgaagataat accagcttga acctgcccat tgtggcatgg tgttagtctc acgacgacct
    20221 ttaacaccat cttcacgagt cacttccaac cagtctgtca cgttagcaag tgggctctca
    20281 ccagtacctg aaggacgaat atccttagtt actggaagaa ccagtggcaa ctcactctca
    20341 ggaaccgctg ttgaggtccc atcttcccag tggatgattg ggattggctc accccaataa
    20401 cgttgacggc taaagagcca gtcacggaga cggtaagtca ctttctcatt accgacgcct
    20461 tctgcttcaa gccattcgac cattttggca atagctgacg ctttatcgag accatctagg
    20521 aagcctgagt tgatgtgaag accgtcttct gtaaaggcag cctcttcaac attaccacct
    20581 tcaagaacag agatgatgtc taggttaaat tgttttgcga attcccagtc acgttcatcg
    20641 tgggctggaa cagccatgat agcaccagta ccgtagctag caaggacata gtccgcaatc
    20701 caaactggca tttcgttacc attaactggg ttaatagcgt agctacctgt ccagacacca
    20761 gttttttctt tggcaaggtc tgtacgagca aggtctgatt tgagacttgc ttgacgtttg
    20821 tagtcagcca cggcttctgc ttggtcagct gtcgtaatag catcaaccaa ggcatgctca
    20881 ggagcaagaa cggcgtaagt tgcaccaaaa agggtgtcag gacgtgttgt aaagacagtg
    20941 aagtccttat ctgtatcctt aaccttgaag gttacattgg caccagttga tttaccgatc
    21001 cagttgcgtt gcatgtcctt gattgattct ggccagtcaa cttcttccaa gtcttctagc
    21061 aagcgctctg cataggcagt gattttgagc atccattggc gcatgggttt tctgacaact
    21121 gggtagccac cacgttctga tgtcccatca gggagcacct cttcgttggc gatagctgtt
    21181 cccaattctt caacccagtt aacgggaact tcagcttcgt aggctaggcc tttttcataa
    21241 agcttggtaa agatccactg cgtccacttg tagtagttag ggtcagttgt gttaacttca
    21301 cgatcccagt cgtatgagaa accaagagca ttaatctggc gtttgaagtt agcgatgttt
    21361 tcagctgtaa actcggctgg gtcattacca gtatccatag cgtactgctc agcaggaagt
    21421 ccaaaggcat cccaacccat tgggtggagg acattgtgac cttgggcacg tttgaaacgg
    21481 ctgagaatat cagttgctgt atagccttct ggatgaccaa cgtggagacc agctccagat
    21541 gggtatggga acatatctag ggcataaaac ttaggttttg atgcgtctgt tcctgtttta
    21601 aaggtgtgat tatctgccca aaaggcttgc catttgggtt caatagcggt gtgatcgtaa
    21661 aatgtcatgt gaaatctccc atgtaaaaaa tctagtcttc ttattatagc atgagatgaa
    21721 gcttttagga atggtcaaga catgactagc gccttggctt ttgagacttc agacgattag
    21781 ctatttttaa accctgcttt agcatcaacc atcctcacaa aaagctaata aaaaagccag
    21841 acttgctctg gaaacagagc caatctggac aaatagactt aaaaagcaag tgcttgctca
    21901 aaatcggcca ataagtcttc gatattttca acaccacaag acaagcgcag caaaccatca
    21961 acaacccctt gttccaaccg ggcttgtgac gataaacaag catgagacat cgttgctgga
    22021 tgtgacaaaa tggactctac tccacctaga ctaacggcta aaatcggcaa ctgaatacga
    22081 tgggtaaaga tcatcagctc ctccttagaa gccaactcaa aggataaaac agcaccacca
    22141 ttcttagctt gttgcaggtg ggtatcgtga ttaggatgac tgtctaagcc ggggtaatgt
    22201 actttaagaa ctttggggtg cttcgctaaa tagttagcga gctgctgagc attttttacc
    22261 gcttgttcca tacggatccc catagttttc atgccacgaa gaatcagcca agcgtcttcg
    22321 accccaacaa ttgctccaaa gtttttttga aaaagcttga gctggttgta gatagcctca
    22381 ttattggtag cagctaaacc agctaccaca tcactatgac cattgataaa tttggtcaca
    22441 ctttctacca caatatccac acccatagct aagggttctt gatacaaact ggtcataaag
    22501 gtattatcag ccacagttag cacaccataa gctttggcga gttgcacaag ctctgaaata
    22561 tcacaaattt tcaagagcgg atttgacggt gtctctagat aaatcatacg cgtattaggc
    22621 ctgatacttg cttttactgt tgctaaatca gccatatcta caaagcttgt ttcaatctga
    22681 taattgggta aaatagctgt cgcaaattga caagtccctc catagacctc caatgggaaa
    22741 atcacatgat ctccagcttt taagagcatc aaaacagttg aaatagcagc cataccagat
    22801 gcataagcca ccgcataagt cgctttttct aaacaggcta acccgtcttc taaagcttca
    22861 gtcgttgggt ttgaaaagcg tgtgtacaaa tgtttttgac taggacaata cagttctgaa
    22921 ttgtggaacg tcgaagtctg atagatggga actgaagctg ctcctgtaaa ctcgtcaata
    22981 accgtatagc catgtaataa ggtcgtattt tctctcattt cgtgcacctc cgcaatagcg
    23041 ttaactccaa tgaactctct tttagacaat ggtcccaccc caatggttgc acaaaccaaa
    23101 aagctcttca aaaaagcgtg atctgctaac ctataagaaa agtagtgggc accttttaaa
    23161 cggataatga atttttccaa caatatcatt tttagatcga ttacgtttat tatacaacct
    23221 ttagctaagt ttgcaagccc ttttatcatc tttgaccaag ctgccaacac ctctccagca
    23281 agttaaagta tagttacctt tggccccatc gtctcaaaaa ctcagcttat cacactgaca
    23341 gtcctacttt gcatcgtcac ctactcaata tggcaatatt accatcaaaa tttcattaaa
    23401 agatcacaat ttatttcatt taatgaaaaa cagaacttgt tttcaccatg cgccttatag
    23461 tacactacta aagtactatt tatttttagg agagaaatat agtgaaaaac aaattatttt
    23521 tagttgccct tgcgaccgta actgtcctag ggccctcttt agcaacccct catcaccgga
    23581 ccgtgcatgc gactgaacag acagtaactc aaagaacagc tactgaaaca tgtacattaa
    23641 atggaaaaat atgctatggt tatgaaaatc ccgatgaaga ctacaccgat agcatggttc
    23701 aatctaagtc tcaagatcaa ggtttcttca gttggctttg gacacaaata acaacttggt
    23761 tttcctcatt aatgagctaa aaccatctcg tggcggtttt ctaatcctag gtcgccacat
    23821 ttcttattca gataaataat aataaaaaca ttaaaataac acttgattta ttaacaaaaa
    23881 gttagtgtaa tataatcaca atacaaatta aaggagttat ctatgaaaaa gaaattatct
    23941 ttatttatga tcgcaactgc tgctgtcgta ggccttagcc ttgcaacacc agaaaaccaa
    24001 actgtttcag caaatgcaca gacaccagct gttcaaaact gtgaaaacgg ctgttgtgac
    24061 cgccctttct ttgggtattg tggacctttc agctggcttt actataatac aagatatttt
    24121 ttggggtatt ctgatacagc tactaaccaa taaatttgtt tctatagtga gacaaaagcc
    24181 caagcctgtt tacgcagtcc tgggcttttt tgctgtccta aagtcagggt gttgccacag
    24241 cttcaaatcc aaaaacaatt aaaccgcacc ccaacaatta gacataggct atgtctccag
    24301 aatcctggac acatatcact aaagcctaat gattaaggtg cagtttaagg tgtggtagca
    24361 aggaactgtt ttaaattcgt ctgcgtctaa ctatacccac tggctatgga gtcagcttag
    24421 agttgattat caagtgtcaa atcaactttt cccaccaatg taaaatgagt ccccatataa
    24481 acttgacagg aagtaacaaa gggtagcttc ccccaaatcc ttcattataa ccctctttgt
    24541 acccatcttt ataaccatct ctataatgct catgattaga gtcatcaata tccttaggtg
    24601 attttggtac ttcagggtca ggtggggtca aatcggtcca ttcggctact tttccatctt
    24661 ctttcccctt tgttaaatct tggttatagc ctaatctcca agggtcttta tcctcctcat
    24721 ctgccataac aggtcttgct ataagcaaca tagcagtaag tagagccatc aagaggtaga
    24781 cgaagtgtag tggcttgtaa gattgttgtt tcatgataat agttatctcc cccttttatg
    24841 ttatgctttg cttgttaaaa agcatcttgt tagtattata gattagaagt ggcttagctt
    24901 caaggtaact atgtaagaaa agaataactt tttgattagc atatcaaaaa acttgtctat
    24961 gaaaatatct catagacaag ctttttgtat ttgtgtgagg agtaggcaca tggcctcaag
    25021 agataagcag catcaaggtg cttgacgaac ctcttgaacc agtcctactt ataagtaatc
    25081 gaaccatatg ggctcaaggt tgatcctgag atgttgacat tgatttcttt agacagtttc
    25141 acatctcttt cgtcgatcac ttttcgccac cattcccaag ctaatccggt gcactctcta
    25201 gccatgatac ggatatttcg tgaattagct cctagtggga taactgtgct aaatggtgat
    25261 gtcttactat accagttgtt gtcccaacgt cgttttgtaa tcacttcttt tcctttgtca
    25321 tcataattga tttcatccca aaggatttca tattgagcaa cataggcacc ttgatgagac
    25381 aggttaattt ttccactcgt gtactcggta gatgttgttt caacgtattc acttctgtta
    25441 ttgacacccg caattttatt atttttaagg aaaacactgg tgtatgaaat aggataagct
    25501 gggttttttc tactgaaggt agcattatct ttgataacgt ttctaataac atcaaagtct
    25561 tttgtgacta ccttattgtg ctctgcagca tctcctccta aaacgacagc tgtaaatgaa
    25621 ctattttcta aaatatcaga gtattttcca ttagttttaa catctgttcc ttttagagct
    25681 gcactaaagg ccgcttcaac atcattactt ttagaacttg tttctagttt gacaaaaaca
    25741 gttcgaccat aagctacgtt actcacaaag agtggcgggg cttcattgct gacacctttt
    25801 cgttgcaact ctttaaaggt cactgattta tcaaacacat ccgcaggatt attaggaagg
    25861 tttgctgata cggtgtaaaa aatttgcttg tatgctgcaa tcatcacctt cttttcacct
    25921 tttgaaatcg acttgaaatc aatgcctaaa gtaccatcta agattttact attaacattt
    25981 agagctgctt caatctgtga tttagaatat accattgatt cagtatattg tgttctggca
    26041 ggaagcgtat taccaccaga ataattatca tgccattggt taacaagatt atcaatagct
    26101 gttgaaacat tggcataggt agggtcattg acctcaaccg ttgctttgtc tcccatacct
    26161 ggtaaatcaa tatggatttt ttgtgggttt cgcttggtga ctactgcgtc tggtttgttt
    26221 tcggtaaaac ctttattagc cagctgaagg gctgctggat aggtcctatc agtgacagag
    26281 tcaatgatgg aaatatcgac cggtgtagtg ttgatatttt ttttctttct ttcaatgaca
    26341 ataaatttgt cagctttctt aacgccttct ttaggaacaa agttttcaat ggtttcacca
    26401 tttttagcaa gtacttcaag ctcattataa tttagtgaat aaatcttgtc attgatttct
    26461 tcagtatgat cttcttcgct ttttttattg tcttctgact ttttttcttc tttttctgca
    26521 gattctagtg gcatttcttt gggagcaagc ttaatcatat cgttagagtt aagcatatca
    26581 tccattttct gacctgcttt ttctgtagtt agctcactac tttctggttt tggttgttca
    26641 tttgtcgttg tggtttctgt attggcagtg ttttgtttgt tcgagtcagc attagcagta
    26701 acaagattac caacgataag agctgccgtt aatagcccag cgacgcgact gtatttttta
    26761 aatatttttt tattagacat gtccttcata cctttttatc attctaaaat gtttctattg
    26821 ttctttcgac catatcaagc atagtatctt gatagtgagc aaattctcct aatttgtaat
    26881 gtgccatagc ctctctaata tgcgcatctt ttaacgcttt ggttatatta gctagtatgc
    26941 tttgacggtt taaataaaat ggcaagcttt cgtaataatt taataacatg ttttcagcgt
    27001 ttagggtttg aaccgcttgg taaatgtcta atgcttgacc gctatttgac atttttaata
    27061 atgcttcttc gatgttagct ttcaattgag tatagccttt tatgaaagca gggtaaatcc
    27121 catactctaa aataacttct ggatcagaaa tatctcccat ataggagtct cttttagtga
    27181 tacgatactc tttgtcacta cctatcaagt atttttttaa atcattaaca gttacttctt
    27241 tttgaaacat tttttggtaa tgttctaaac cctttggcac cttatacata ttgttacttc
    27301 ctatcttgca ttttcttaat tttgaagcga ccagttactt ttttatggtc accatttgga
    27361 gcaatgatgg taggatcaat aatctcaaaa tagcctttgg catcaatctc tgctaagaca
    27421 gctttagatt ttagatcttt aacactaatc gatgggaaaa ttaattcact ttctgaattt
    27481 tcaatgtgtt ttcctgacca cgtttggcaa ccaggaatgt tgagcgaatt tgctccagga
    27541 gtatctccgc tagctgttcg gatatagcct agcttatcaa tgttttttgt tagttcagaa
    27601 tcgtactcat attgataaac cccatcgcta tattttccgc tatcgacacc ttttatattt
    27661 tcaatttggt cagctgattt taacttacct tgatcagtaa agagcaatgc catatcttca
    27721 gcaaaacttg tcacaaaaag accgttttct tgtcgaccaa tcgtcgactt tcttttagca
    27781 tcatcaaaag ctaacatcaa atcttttttg cttgtaacgt gggaagctcc gctttctttg
    27841 tagacttgtt ttagtttttc aacaaactct tttttgtagt ggtatttgcg gctaacgtac
    27901 atacggtaat actcagcacg tgacgcaaca gcagacatct gaacagcttt atcagcatac
    27961 ttgtcggcgg tttcaataaa ctcatctgct tgtttatctg ttacccattt atctttaatt
    28021 tctttaaact ttttttcaaa aatatcgcgt tccatattgc caaaagtgac ctctgacaag
    28081 gctaaaatat ccttgttttg accctgatgg acctctgtta cctcaatatc aatacgatca
    28141 acatctaatt ttttatcaat ctcaatgtga tgcggttttt tagtgtaggt gtcgcctaat
    28201 tcaatttttt gaaagaggac caatttattc ccgttatagt atttaacatc agcctttgca
    28261 attctatttt tcttgtagta attctccttg ctagatgtat ctccattaac aattaaaatt
    28321 ctcccaatat gcatcgggga cgcaaacttg taagaaagta cctcaccaat accaccgcca
    28381 ggtgaatttt cctcccaaac agtactcatt gagccgtcta atgtgtgcat gacatgtttg
    28441 tcttctttag aggaagtggc gttagcttcc ataactttgg tcatttcata tttgacatcg
    28501 ctttttttac cttctttgcc actaacagcg tacgttgtgt tattagctaa taaactgcta
    28561 cccattgctc cagccaaagc aatagcaaca cttgtcttcg cgacaatatg agctaatgtt
    28621 acttttttgt ttctcatgta aaccacctta tattattttt aagtaaacta tacattaaca
    28681 aatagttttt gtcaatgcga tttattaaca tcgttttagg attttctata aaaaaaatga
    28741 acaaaaaaca agtaggcaac tgttacagtt ttcaaggtaa tatgtgcatc ttatcatcac
    28801 agaaccttca catctgttct atttaaacca gattaaaagt actagttaag tatttgatag
    28861 tagcagcgtt atcagtaata gatctgttaa ttatctctga ttacaatgat gttaacaata
    28921 gtcatacctt tatttgtaca cacgcttcac ttccaactaa aaaaggtctg atggtaatac
    28981 ttataccatc agacctttga gagcctatag ttctgcgatt tggtaaagtt caacttcggc
    29041 tactgtttct gatccaaaca tgttcaacat cagtttcacc ttgttatttt caatctcaac
    29101 cacacgacct tcttgtccca taaaggcacc gtcaatgatt tgaaccacat cgccctcttt
    29161 gatgttggta tcaaagacat caatggtttg ccccatagat aataggatgg cacggatttc
    29221 ttcttcaagt agtggcgttg gtttagaacg gttcccgtgt gaacccacga acccagtaac
    29281 gtttggcgtg ttacgcacca cgaaccaagc ttcatctgtc atgaccattt ctaccaatac
    29341 ataccctggg aagcggtttt cttcgatttc tttggtttgc ccattttttt caacgttaac
    29401 cgtttgtgtc ggaatttcga cgcgcaaaat attgtccaac atgttatagg tttgggcacg
    29461 ttgcaagagg ttttctttta ctttgttttc gtagcctgag taagtttgga ggacgaacca
    29521 gcccttatca aatgaatcta gcatgatgtt tcctttcatt ataaaaaagc cctttttttg
    29581 gcttttgcgc tgttttctat caccttcatt ataataaaag acagggctgc tgtcaacgta
    29641 tctgtggagc tacttgacac ctttattaaa aagtccaaag tcggttcgtg acgactctgg
    29701 acggtattgt acagttttag ttttcaggaa ctgtgatggt tccttcgata atcgcttttt
    29761 tagcagcctc aatagctttt ttagtgtctt gtgtcagagc atccgttgta aggctaacac
    29821 caccttcttt taaaccaaaa gtggttattt gaccacctgg gaattggcct tctgaggttt
    29881 ttacggctac ttttactaaa gcttttccga cttccttgat acttgaggtc aaaacaaaat
    29941 tagctgactt gccatctttt gtggtgtatt ttccatcttc actttggtca cggtcaacac
    30001 caataaccca aaccttatct tcttctttac gtttttcgtt gatagactta gcttcgctaa
    30061 agacacccgc tcctgtgcct cctgctgcat gataaataac atctgcgcct tcagcgtatt
    30121 gagcagctgc aatcgtcttg cctttagcag catctgcaaa agagcctgca taagcaactc
    30181 ttactttgat ggtatcatct actgatttca caccagcttc aaaacctttt tcaaagcgct
    30241 tgacaacatc tccttccata ccacctacaa aaccaacttg cttggttttt gtcgttttag
    30301 ctgctgcaac accggctagg tatgccgctt catggtctga aaaggtgata cttgcaacat
    30361 ttttttgacc tttaatcaca tcatccacaa ttgcaaaatg gttgtcagga ttgtttgcgg
    30421 ctactttttc tacagcgtca tgtaatggaa atccaatccc aaaaacaaga ttataaccat
    30481 tggttactgc tgactcaagg tttgtggtaa actctgattc attggctgat tggaaataat
    30541 catagccttt tcctttttca agtttatttt cttttcccca agcttgcaag ccttcccagg
    30601 ctgactggtt aaatgacttg tcatcaatac ccgtctgatt agtaatcata gcgattttta
    30661 atgaattgtc agttgtttgt ttagcggagt tattggtaca gcctcctaat gtgaataggg
    30721 cagtcgaaac aagaccaagt gacattactt ttttgttcat gtgaaaatga acctcctaaa
    30781 tgtttaatcc taaagtgatg tgtcattgtt aacgttctac ttatgctcta gaacgaaaag
    30841 tttagtatat caaaaaaatc agttttatcc tactattttt gttgaaaaat ctctttttca
    30901 ccaaaatgac cgaacgataa agtgagatca actggtaaat cccattatct cctcaaaaat
    30961 cacctcttaa ggagataagt caacgacaaa actcaagcta ctagtaatag catgactaac
    31021 tataccatcc aacaagcggt aaaaagagct ggaaacgcta ttcaactctt tgtcatacta
    31081 gacaccttag atagatgccc agaccgactc aagaatattg gtctgttcac gtcctggacc
    31141 aactgagaag gttgaaatgc gaacgccaac caattctcca acacgacgga catagttgcg
    31201 ggcattttca ggcagctcat caaggctacg aacacccgtg atgtcctctt gccagcctgg
    31261 taattcttca tagattggtt tgcaacgttt gagttgttca agacttgctg ggtagtgatc
    31321 aatacgttca ccatctaaat cgtaagccac acaaatctta accgtatcaa gtcctgaaag
    31381 aacgtcaatg gaattgaggg aaaggttagt aatccctgac acacgacgac tatggcgcat
    31441 aacaactgag tcaaaccaac ctacacgacg tggacgacct gttgtcgtac cgtactcatg
    31501 accaacttca cggatacgtt cacccacttc atcaaagagt tctgtaggga atggcccatc
    31561 accgacacgg cttgtgtagg ctttacagac gccaactact ttgttgattt tacttgggcc
    31621 aacaccagaa ccaatggtta caccaccagc aactgggttt gaagacgtta caaatgggta
    31681 agttccttgg tcaatatcaa gcataacccc ttgtgcacct tcaaaaagaa cacgtttacc
    31741 ggcatcaagt gcatcattta aaattacaga agtatctgtc acatattgct tgatttcttg
    31801 accgtaagca tagtattctt caaaaatagc atcaaaatca agaggtgtac tgtcatacat
    31861 tttttcaaat aaacggtttt tctcagctaa attaatgcgt aggcgctctg caaagatatc
    31921 cttatccagt aaatctgcga tacggatacc aactcgagca gctttatcca tataagctgg
    31981 accaatccct ttaatagttg ttccgatttt attgtcacct tttgcatctt cttgcagttg
    32041 atccagctgg atatgataag gtaaaatgac atgagctcgg tctgaaatgc gaaggttatc
    32101 tgtcgtcact ccttcatcat gcaggtacgc caactctttg accaaagatt tggggttgac
    32161 cacaacacca ttaccaataa cggaaatttt ttgcgggaag aaaattcctg atgggatcaa
    32221 gtgaagttta aacttcttac catcaatcac gatcgtatga ccagcattat caccaccttg
    32281 atagcgagca attacttctg catccgctga caagaaatca gtgattttac ctttaccttc
    32341 gtcaccccac tgggtaccaa caacaactac agatgtcata tcattgtcct aactttctga
    32401 aacacttatt ctcaataaaa atcataggca agctaaccac tgcttaaaaa ccaaaaagaa
    32461 ggtcagatct gtaagatcag caatgtagct cttgattttt aaagaaaaca ggcaggaatc
    32521 tcacctgcta gcatatatct tacaacttat tatagcaaaa aatgattttt tctgctagat
    32581 ttcttagcat tattaaggaa aaagagaaac tcttttttta accatgataa acaatcctaa
    32641 aaaaacgaac attataagag aaaagctttt aacctcgttt ctcctaagct ttagcagggt
    32701 taaacgattc tcttaaaaca ttagctcttt tctttcagaa atagcggttt taaggtaaaa
    32761 taatagtaag ttacctctat gagatagcca gtaaaaacat atcgaggaaa tatcacatga
    32821 ttagaaagta tgaccgcacg agcacaaaaa agaaatcact aaactggatt tggctaatca
    32881 tcgctttttt tatgatttca agctttatag gtggctcttc ttttactgag tcacttctag
    32941 acattttgcc tgccatagcc attggtggta caggttatgc tatttttcgt gttagatctc
    33001 atcaaaagcg gctagcaaag gccaaggttg ccaaacaatt agaagatcta aaagcaaaaa
    33061 ttcagctagc tgatcgtaaa gttcggctgt tagatactta tttggcagac catgatgact
    33121 tccaatataa cgtactagct cagcaattat taccacaact tagtgacatc aaagcaaaag
    33181 ctattacgtt aaaagaccag ttagatccca aaatttatcg tcgtatcacc aaaaaagcca
    33241 atgacgttga aagtgatatt acccttcaac tcgaaacact gcagattgcc acaactctta
    33301 accctcagcc tttgaaaacc ccatctccta atcttattaa caaagcacct gagctcaaac
    33361 cgtattatga taatattcag acagatcatc aagctatcct tgctaaaatc caaggagccg
    33421 acaatcaaga agaattgctt gcgctgcatg aagctaacat gaggaggttt gaggatatct
    33481 taacaggcta cttaaaaatc aaagaagagc ctaaaaatta ctataacgct gctgctcgtt
    33541 tagaacaagc caaacaagct atccaacaat ttgatgaaaa tcttgacgaa acccttcgtc
    33601 gactcaatga aagtgatctt aaagattttg atattagcct tcgaatcatg caaggtgcta
    33661 ctcaaagacg aacaacgcat catcaaaaag actaaaggag tccctttatg gcagatttta
    33721 attttgacat tgaccaaatt gctgacaatg ctgttgtcaa aaccgataaa accaccgata
    33781 ttatctcaga cttaccaact gacacaaatg gccaaatctc tttttttgag aaactaagtg
    33841 ctgaccagca gacagccatt actgccagag ccccggcatt ggtagatacc tttttggcag
    33901 accaaaatgc gctacttgat tttggtcagt ctgctgttga aggggtcaat gcaacggtca
    33961 atcatatcct ggccgaacaa aagaagttac agattcctca ggttgatgat cttttaaaat
    34021 caaccaatcg tgaactcaat ggttttatcg ctaaatacaa ggatgccaca cctgtggacc
    34081 ttgataaaaa gccaaacttt cttcaaaaac tctttaaaca aagccgtgat accctgcaag
    34141 agttttattt tgattctcaa aacattgagc aaaaaatgga tagtatggct gcagcggttg
    34201 tcaagcaaga agatacctta gctcgcaata ttgtctcagc agaattgtta attgaagata
    34261 atactaagtc cattgaacat ttggtaggcg tcattgcttt tatcgaagct agtcaaaaag
    34321 aagctagtca gcgcgctgcg gctttacaaa aagacctaaa aaccaaagac agtgctacac
    34381 cagactatca aataaaagct gatcttttgg caagaactac cgaagtcatc aacaccctcg
    34441 aacaacaaca caccgaatac ttgagtcgcc tctatgttgc ttgggcgaca actccgcaaa
    34501 tgcgtaatct agtcaaggtc tcttctgaca tgcgtcaaaa actaggcatg ttacgccgca
    34561 ataccattcc aacgatgaaa ctatctattg ctcagttagg catgatgcaa caatcggtta
    34621 aatctggaat gactgctgat gccattatta atgctaataa tgctgccctt cagatgctag
    34681 cagaaacaag taaagaagcc atcccagcat tggaacaatc agcacaaaac cctactttgt
    34741 ctatgaaatc tgtgacaagt ctggcagaaa gtttagtagc acaaaataat gggatcattg
    34801 cggcgattga tcatggacgc aaagaacgag cacaactaga aagtgctatt atcaggtctg
    34861 ccgaaaccat taacgattct gtcaaactac gtgaccaaaa tattgtgcaa gcacttctta
    34921 gtgaaggcaa ggaaactcaa aaaacaattg ataaaacaac tcgcgcataa gctaaacatc
    34981 acctgtcacg ctacttaaaa agcaagccat cagttaggtt aatccctttg atggcttgct
    35041 tttttactac ttaacgaata atcgccttgt ttgatataac acttatcttt tatgatgtta
    35101 ttttcataat acgaacaagg ctagcacgct cggcctcttc taatttcaac tcaatgtaat
    35161 gaatcgtctc tttcagttgc gggataatag aatactctaa gccattgacg cgacgtctag
    35221 tcttttcaat gtcatcagcc attagttgac aagttttttc aacttcagct aaccgtaaga
    35281 gcttttctaa tagttctttt gtcttttgga tagtattgtc catctcacta tttgagctga
    35341 ggtaactata agcaaactca ccttgttctt gctctcttgc cgtattagac tggacatgga
    35401 atttaggcac attgacactc atgatatttt caatatcaat ccataaggtc acttcatgga
    35461 ctggaacagc aaagagttct tctaccatta gactattttc ggatgctttt gccaagacaa
    35521 actccttcat attggcagca agttcttttt cgatagtttg acgaagctca ttgttttcac
    35581 gaattaaatc aacgaagcgg cgcatcaact catcccgctt gtcctttaat aatttatgac
    35641 ctcttgtagc tgtcttcaag cgatttttca agttactaag ttccatgcgt gttggtttaa
    35701 catttaatcg tgccattgat ataactcctt tcgtcaagga cttgaaattg catggtcaac
    35761 tcaatcattt gcaacaaaaa cctttgtcat cgtggtatct gctttaggca aataacgatc
    35821 taacatatca tctttaatgc gttttaattc ggtacgtggc aaaatcgaca acaattccca
    35881 acccaagtca agactttctt caatgctacg gttggtgtaa aatccttggt taatgtattc
    35941 ttcttcaaac cggttggtaa aggccacata tagtttatcc gtttcagaaa gggctgattc
    36001 accgagcaca acagccaatt ccttagcttg ttttccttgg gcataggctg caaagagctg
    36061 attcattgtg gcagcatggt cttgtcgagt cttaccttca cctgagcctt tatcttttag
    36121 gcgagatagc gatggcaaga cattaatagg cggtctaaaa ccatttttat atagttcttg
    36181 cgacaaaata atctgacctt cggtaatata acctgtcaaa tcggggatag ggtgggtaat
    36241 gtcatcttct ggcatggtta aaataggaat ttgagtcact gacccttttt tcccgatcaa
    36301 gcgaccagcc cgttcatata aggtggagag attagtatag agatagccag gataacctcg
    36361 tctgcctgga acttctctgc gagcggctga tacttctcgt aaggcttcac aataatttgt
    36421 catatctgtc atgatgacta aaacatgcat acctttttca taagccaagt attcggctgt
    36481 tgtcagagct atacgtggtg ttgcaatgcg ttcaatagca gggtcattag ccaaattgat
    36541 aaataaaaca gatcgatcaa tagcacccgt ttcacgcaag tcattcataa agaattctgc
    36601 ctcttcaaaa gtaataccca tagctgcaaa cacaaccgca aagttatcat cagagtttag
    36661 aacagttgcc tgacgagcaa tctgtgcggc caattcatta tgaggtaacc ctgagcccga
    36721 aaaaactggt aacttttgac cacgaacgag ggtattgaga tgatcaatag ctgagatacc
    36781 tgtctggata aattcgtctg ggtaatcacg agcgacagga ttgatcgctt gaccatcgat
    36841 atcgaggtat ttttcgggaa taagttctgg accgccgtct atgggctgcc ccattccatc
    36901 aaagatgcgc cctaccatat cttctgatac ggctaattcc aaaggatgcc ctgtaaatcg
    36961 aaccttggtt ttggctaggt tgatgccagt tgatccttca aatagctgta ccatagcctt
    37021 atcaccttgg acttctaaga cttgaccttt acgcctttct ccattatgca aagtaatatc
    37081 taccaattcg ttgtagtgca ctcctgcaac ttgatcaaca atcatcaaag ggccaaccac
    37141 ttcgctaacc gtccgatatt ctttgagaac gctcatctaa attcctccct ttgctaaaac
    37201 gtggtgaatc tctttggtaa ccttctgagt aagcccttta atctgctcta agttttcttc
    37261 tgggataaat ttgctgcgtg cgatgcgatc gcgtacctga gcagtgcctt ccataatctc
    37321 attaaaataa gctcccaaag aaagggcttt gctggcttcc tcattaaagg tcaaaatatt
    37381 ggttagcatg gcctcttgtt tcggaaagga agtaaaggta tccaccgaat caaaggcatt
    37441 ttgctggaga taatcctccc gaatttgccg ggcaacagcc atggtcaaac gatcttgttc
    37501 agacagtgaa tcaagcccca ccaagcgtac aatttcttct agactggctt cacgctgcaa
    37561 aatagccatg gcacgagtta ccttgttgga ccaattagat tgctgtttac ggtcaatata
    37621 gcttcctaca tcatcttgat acaatgaata agacgtcagc cagttaatcg ctgggaagtg
    37681 acgccgttgc gcaagaggcg cgtcgagccc ccagaaaact ttgacaatcc gaagggtgtt
    37741 ttgagtgaca ggctctgaaa tatcccctcc aggaggagaa accgcgccga tggctgtaat
    37801 ggttccctca cgttcttgac ttcccaaggt ccgaacacga ccagcccgtt cataatattc
    37861 ggcaatgcga ctccctaagt aagccgggta gccttcatca ccaggcattt cttgtaggcg
    37921 tcctgacatc tcgcgcagag cttctgccca acgtgatgtc gagtctgcca tgatagccac
    37981 agaatagccc atatcacgga aatattcggc aatggtaatg cctgtgtaaa tcgacgcttc
    38041 acgcgctgct actggcatat tagaggtgtt tgcaattaac accgtgcgct ccataatgga
    38101 ctggcctgta tttgggtcaa ttaactctgg aaactcattc aaaacgtcgg tcatctcgtt
    38161 gccgcgttcc ccacaaccga cataaataac aatatcaacg ttggcaaatt tagctatttg
    38221 atgctgcaca actgtttttc ctgccccaaa tggtccagga acggcagcgg caccaccttt
    38281 tgtaacaggg aaaaaggtgt caataacccg ttgacctgta accaaaggct cgactgggat
    38341 aaacttttga gcaacagggc gactttgacg aactggccaa gtctgcatga ggctaccttg
    38401 gtaaatggaa ccgtcttcct gcttaatttc ataaactgta tctgttactg tgaagtcccc
    38461 tgcatgaata gccaccaagg tccctgaaac tttataagga accatgatac gatgctcaat
    38521 gacagctgtt tcttgcacag ttcctaaaat atcacctgca actacttctt gaccaacact
    38581 tagcttggga ataaatgccc acttagcctt tcgatcaaga cttgggatag ccacaccacg
    38641 gattaaaaag tcgctgtccg ttgctttttg aaaacgatca agcggtcgct gaataccgtc
    38701 aaacatttct gaaatcaggc ctgggcctaa ctcgaccgac aaaggacaac cagtagtcac
    38761 tactggttct cctggaccga tccctgatgt ttcctcataa acctgaatag acgcttgatc
    38821 gcggcgcatt tcaataattt ctccgactaa gccaagatgt cccacacgac aaatatcttg
    38881 aatattagct tcttgcatcc cagaagccac aacaagaggt cccgaaacgg ttattatttt
    38941 tccttggttc acctttttcc tcctttattt tttccaaatc atactaacta atctatactg
    39001 tcaaggttta atgtgactat tttgaatagt cagcaaacta tcctatgcgt tcagctgcta
    39061 acttcaccaa ttttcctgtc cttgcatttc atcagttagc tactcataag cctcaaacag
    39121 agtataagtc ctctttgcct aacgtcttag tgttataaaa tattttgacc gacagccttt
    39181 tcaaccatgg cttgtatgcg tgacaggcct atcccttgcg ctccttgatg agttggtaat
    39241 ggtatgactg ctggtagaac ttgattatca tagtgagtga gggcttctgg aatagctgca
    39301 gcaatatctt ctgtgatata aataatacca aagtcttcca ttgctagttg acgcaactgg
    39361 ttaatagcgt cttgtggttt tattactgga aaagtttgaa acccaatcat ctgaaaaggt
    39421 aaaataacat ctctattacc aattaccccg actttataca atgttttggt catgctattg
    39481 gtctcatcct ttctatgaca cgttctttgg gtaaatcatt agctaaagca gccgctaaaa
    39541 gccgtaggtt ttttacttca aacgatttag cgagcaaaaa gcgagcaagc acataaggcc
    39601 catcgacttg atatttggcc ttcgcaaata aatggtaaag gcattcatca acaaggtatt
    39661 ctaactcagt cgtttgaaga gtgccttggc gaagtttctc tgaataaggt tttagggctg
    39721 tcatatagct atcaggtgtt acattttcaa accacgtcat cagatcctta tcatcttcaa
    39781 gtgtgataaa tgttttactt ggtctacttg cttcatcaga taataactgc atcatgaaac
    39841 ttattggttt attttgcgat ttggcccgtc tgacggtaat cagattatac aaatcaatca
    39901 caataagaac agcttgttgg aaaacagggt cctctaatct ttgtgctatt tgtttcaacg
    39961 ccttaaaata agctaagtca gtaccaattt ctaagacgcg tatgtcttga taatcttgat
    40021 attcggccca aatggactgg atttctgtta ccacctcttt tggaaactca tcagaagtca
    40081 tcgtcctaat caaatgttcc aaagccacca aaggcttgtc accaattggt agtaataagt
    40141 gactcagatc tgcttgacta gctttagctt ttaacaacac tttgacatta tgataggtgt
    40201 aacgcaaggt aaataattgt actatgtcag gttgaggggt ttctgcaaaa gcccagcgat
    40261 aggtcttggt tagctcagcc attaagatag attctagccg atccaaatcg ttgagatcgt
    40321 caacagttag gtgatagact gactggtgca acagtcgagc taaggttgtt gtattgggag
    40381 cctgcaatag cttatcaaat tgctctttag tcaataactc tttttctttg acactgatag
    40441 tagtgtttaa ttctagaaat gttggcatcg ctagtcaaac ctcctatatc tctgaaaaaa
    40501 gcatatcaat gatgcgggag ctttcttctt taagaactga ttctaaaagg taacggtata
    40561 aataattgtc atcgacttgg tctaaactga ctaaaaatcc tgcttcctga ggaattagct
    40621 cttgattata gcttaattga ggaaatgcta atctcagctc agcacaatca taagaactga
    40681 acttttgccc tgttttttcg ccaaaagtaa cttgcaatgg ctgttctgga tatttagaca
    40741 agacttgctt caaaaaagcc aattcttctt ccttagaaaa gttcgtcatc ttctccaaag
    40801 aagcttcaaa tagctccttt atactgtctt gttttaatgc tagtagagct tgtctttctt
    40861 ggtttttgag ttgctgctgc gcaacctgaa attgctgttc aaaagctttt aactcttttt
    40921 gacgctttgc ttttaaatcg tgtagtcctt gctgttgacg ctctttaaag tcagtatcaa
    40981 gactatctgt cgctatcttt aggcactgtt gaccttcttg atgtgctttt tcaagaacgt
    41041 tttgtcttaa ctgtgttata tcattcacct aatttccccc ttttgatagt gttagtggtg
    41101 tcaccgtttt ttaaaatcta gataaggacc gttaccttat ccaattttat ttaagagaat
    41161 aaaggagacg acaaaggcaa gaatagcata ggtttcaacc atagctgcta aaatgacacc
    41221 cttcataaaa tctttagggc gcttagccaa gatttgcata ccagctacag aaacattgcc
    41281 ttggtgcttg gccgaaaaat aaccaacaat agcaattgga agagatacca aaaagtaagc
    41341 taatccttgg ttaactgaaa gttctggtgt cagtttcatc caaattaaaa taccaatagc
    41401 aaagccgtag attccttgac taccgggtaa cagttgcaag ataagcgcag acgtaaattt
    41461 ttcgggttct tcttttaaga gcgcagctgc cgcttgacca cctttaccga caccataagc
    41521 tgagcccatg ccactaagag ctacggctaa aacaattcct aaggctgcga agaaaacgcc
    41581 accatgtgct gtaaaataat gtgctaaatg ttccatgtta attgtcctcc aaatctgttt
    41641 cttcattgac attgacataa ttatcagcta actttaaagg attgaaagct tttcctccac
    41701 cttcataaaa ttttccaaaa aactctacga aaataagacg agcaccatgc acatatcctg
    41761 aaagcattga taagaaaata ttgatcgcat gcaaaagaat aaaaataaat atacctactg
    41821 taaagcgcgt gactggtgga aaaatcccaa caatcatgtt aaaagccgct ccaatactag
    41881 ctccagaaag ccctaatgcc attagacgag taaagctaac caaatcactt aagtaagagc
    41941 taatgccata taaattatat aatccactac ctagacctaa aaggcttttg ctttttagta
    42001 aagaaacaac caaaatccca aaggcattgc ccaatgcaag ccacttacca ataaccgata
    42061 agtaagcaag gccagataca ttcttaccaa gaataaataa cagcaggcct aataaaataa
    42121 aagtccaagc tagacttgac gtataggccg tagcatatgc tttcatcctt acttgttgcc
    42181 atgctcctaa caaaagccca aatataagtg taacaaaccc aaatagcaaa gaaacaacca
    42241 aaatagtaat cacatccgtt ttagttgata ataatgccac aggtaagtca aaaccaaaga
    42301 aagaaccgta aataagcccc catagggcta ctgaaatagc taaaatatta aagaaggtca
    42361 ctaaccgttt actggttttt tggagattaa aaaagaccaa tgcagctagt gtcacagcat
    42421 atagcaacaa accatagccc aaatcagcta ccatcatgcc aaaaaaagta aggtataaag
    42481 gagctaaaaa aggtgtcgga tctttttctt gatattttgg caaagcgtac atttctgtaa
    42541 ccaattcaaa cggtgcaatg tagcggtgat tacgtaactt aatgggaaca tcttcccaat
    42601 cgtctggcgt gacatcgtaa ctatccagat aaaacatatc acctagtgtc ttagtcatta
    42661 gcccttttaa ttggttaacc gaatcagctt ctatccaccc ttctaaggct attagatgtc
    42721 ttgtaccgag taattgcttt ttagtttgct gccgttgata ctgactaagg acatagtcta
    42781 tttcaacctg taactgtgcc agtatctttt gagactgcct aagctctttt agtagactat
    42841 ctttttcagc tagccaattc gttagtaact ctttgtttat acgaagttgt tctgatggca
    42901 gtagctgttc tttatataat aagggtttaa actgatattt ctgtaaatga atcgtatctt
    42961 gtgcttgcca aaataagaca aggccgtact caaattctgt atggtatact tcctcaataa
    43021 aaagaccttt gtgcttcttt aactgatgat aaaaatgatc atttgctgta ctaggaatcg
    43081 ttccaactct tgccgacaaa aaatgaaatt gcgctaagtc ctgaggcaaa acagtcaatg
    43141 aacgccactt ttctaactcc tgacagtatt ctgttagctg gtctattttg ttttgcagct
    43201 gctctagtcg ctctatcttt tgtgacatca ttttcaaagc cgtttgagct gcttgttgtc
    43261 gatggcgttc ttcgaactgt ttaaacgaaa gagatggcgt tttttgtctc aaggctgtta
    43321 actttcctat tggtggtaaa aacgctgata agctagcaag gccgttttct aactcttgtt
    43381 ggctttgtaa aaggtattgt aaagcttcat catctagtag aggtttttga tgcgtcagat
    43441 cgtattggac gatttgtggc aacttgacgt tgcctttgtt aaaagcatct tgccaatgtt
    43501 ttagttgctt catgtcacga acttcaacta attgagattg ttgaagtgtt tttaaaacaa
    43561 gatcaagata atctttttca aaaaccattg ccagcttttt catttgacta atggccatat
    43621 gtctccacca ccttatccac taactcccta acaacggtta gcttatgctc ttctaaaatg
    43681 gcatgaagag ctagctgttg cgtcgctaac ctcttttttg aagctttttg ttcttgacga
    43741 ttagcttcaa aaaatacctc acgtttagct tctaatagta gctgagtttc ttgttcgtac
    43801 tcaagaaaca gctgctttaa ctcttcttct tttttgtcag ctagagcttt tttcttagca
    43861 tcgtaactgt cataaattgt tctagcctct tgttcgatac tattcattag tgacaatagg
    43921 gtattcatca catatcaact ccttatcttt atctattgct aattttttga ctcactaggt
    43981 acttaaaaac aaagctacaa gaaaggctac ttttgggggt taatcaacca gcgactataa
    44041 gctagagcta aatctctaac ctatctacta acagcttttt tgagatagga taattgcttg
    44101 attaagcgaa cagcatcttt aagttaagcg ctttcaattc tatccataaa aacaatggct
    44161 tagttcagaa aaaggttagc taaaaacctg tcaaagcagt aagatgacac agaactctaa
    44221 agctttgtat tgctgtcttt cgtgtgttat cttatacttc tttaggcatt tagtaacctt
    44281 gatctagttg acggtaagga acctttacca gccaatagcc aagccaatgt gataacagta
    44341 taactgctat cttgttaaaa gtcctgtcaa aaagatgttt attagtttct cgcttgtaat
    44401 tcttgttttg ttactaaacg gtaattttta aagacagaac ctccaatata acccacaatt
    44461 aagctgataa taatacatcc aagggctgtt atcaacactt tagcgacagg attataggca
    44521 aacatcaccg caaaaccggc aatcggagta gctgtccctg gcgtatcatt aaccaatttc
    44581 attagggcga tcaaaacacc acatgcagca ccaccaacaa aattagtcac ataaatcgga
    44641 atgggattgg ctgacgtcac atctgcctgc gttagtggtt caatagcaaa agcaatattg
    44701 tcttttcttt cacccaattt taatcggtaa aaaagaacac cattcataaa agaagagcca
    44761 aagacagata aggcacctat agccatcgga atacctgtca gaccaagcat ggctgtcaaa
    44821 gccattgatg acagcggagc tgttgctaca acaacaatcg taccgcctag tatcattccc
    44881 atgataatag ggttgctatt agcacttgag gtcaggatgt ctccaatagt caataaagta
    44941 ctattgatca ctggcgtaat taactgcgcc aagaaacgag ttaatggtgc accgacaata
    45001 ataatcgaga ttaaatcaag cccaccagga atattttttt ccatccactt gattaaaaaa
    45061 gataccacat acccagccac aaaacctggg ataatacctg ttcctgaaac tgacaaacca
    45121 atcaaaacgg cataacctgg agacacacca attgcaatgg caaccaagat agcagcagct
    45181 acccctgata atgagccatt tgctccgcct acttcactta gaaactgaaa gcctaaaacc
    45241 ttaccaaaaa aagaatcttg aaaggcttca actaaaaaag aggcacaagc tgccgaagcc
    45301 aaagctccca ttgccttggc accatgagga gccttataat taaacaagct aaaaatagct
    45361 aaaacaagaa tcaaaagact tgttccaata ataatatcca taatctattc caccaatcta
    45421 tctcattaca taagacacta taactgcttc actctggcaa cagcttcgac ttcaatcaaa
    45481 gcttgcaaag gaagcgccga cacttgaacc gctgtccgaa cagggtaggg ctcttcaaac
    45541 aaatcagtca tgacatgatt taatatttcc acattggtca catctgttaa atacacattt
    45601 agcttataga tatgattcaa gtccaacttt tgctctgcca aaatagattg taaattaaca
    45661 aaaacctggc gacactgtgc ctcaaaacca tctgacaatt gacctgtcac tggattaagg
    45721 ggtaattggc ctgcggtgta tagaaaatgt ccttcaatcg tataagttga ataaggaccc
    45781 attggttctg ggtagctctt catatacgaa cctcctcatt gataatatag ttaaatttta
    45841 caggaaaccg cattcacagt caataataaa ttctcttttt gataaaaaat tattattaag
    45901 gtgattggca attgtttttt agtctaaaat gtattactat atttgtaaat aagaagatag
    45961 atataggaag tttgacatgg ataaagaaac gctaaactac tggaaaacgg ttatcacatt
    46021 tcttcacgat gtcttaggtg ataactatga gattatttta catgtgattg ataaaaatga
    46081 tatctatatt ggagaactcg ttaatagtca tatcagtgga cggtctaaac agtctcctct
    46141 caccaccttt gctcttgatt tgattaccaa taaagtctat aaggaaaaag attttgtgac
    46201 caattacaaa gcaatcgtta gtcctcagca caaagaagtt cggggatcta ctttttttat
    46261 taaagataaa aagggtaatc tcgagggaat gctatgtatt aacttagata tttcagccta
    46321 tcaaggagta gctagggacc tcttaaaact tgtcaatctc aatttagaac atttcatccc
    46381 aactgctaaa gaacctaaaa cagtcacacc ccagccagaa gaagctgttg aaattttaac
    46441 ctctaacatc caagatatta tcggtcaaat tattgatccc tcgttactga gacacaatgt
    46501 acatcttagc caagatgtca aaatagacat tgttgccaag ctttatgaaa aaggagtatt
    46561 tcaactaaaa ggagccgtct caaaagtcgc tgatattcta tgtatttccg aaccaagtgt
    46621 ttaccgctac cttaaaaaaa ttgaagccga tcaataacca aatcaccata aaacgccagt
    46681 taaaagtatt tcagataagc atcacaatct ctgatatacc gatgactgac gtttttttac
    46741 tcaatatgcc tttatggcaa gaaaaggcta ctagtcatta accttcagct atgcttagag
    46801 gtacacctgt cgcagcttga acctcatcaa aagtaaaccc ttcactgatt tcaattactt
    46861 ggataccatc tggcgttact ttaaacacac ccatttctgt gataataagg tcaaccacac
    46921 cttttgctgt taaaggtaag gtacattctt ttaggagctt atgctttcct ttattggtat
    46981 gctccatagc tacgatgact tttttagcac caactaataa atccatcgct cctcccatac
    47041 caggaaccat tttgcctgga atcaggtaat tggcgatatc tccattttct gcaatttcta
    47101 aagcacccaa gacagtcaag tcaacatgac caccacgtat aatgccaaaa gaatctgcac
    47161 tattaaagaa agcggctcct ggataaaccg tcacaggctg tcctcctgca ttaacgatag
    47221 tcgaattcgg atcatctgac ttaggaccta gtccaataaa cccattttca gattgaaaat
    47281 acactgtcat ttcttcaggc acaaaatttg ctactttggt tggtagacca atacctaaat
    47341 ttaccaaagt accatcttct aattctttgg ccacacgctt tgcaatacga ttttgaatct
    47401 cttctttact taatgcaacc gccataacta tactccttct ttaacaatgt aatctacaaa
    47461 aatgtgtggt gtatgaacgc attctggttg tatggtgccg actggtacta tttctcgcac
    47521 ctgaacaatt gttgtttttg cacaagctgc catcaattga ttaaaattat tttcagaacc
    47581 actatactgt aaatttccca tttcatcagc tttattagca aatatcaagg tgacatctgc
    47641 ttcaaatggg tattctaaga gataggtttt tcccttgatg gtttttgttt ccttgccttc
    47701 tgccactaag gttcctaccc ctgttggcgt gtaaaagcca ccaatgccat aagctccgat
    47761 gcgaattttt tcggcgaagg ttccttgagg aatgagctca atcgtcgttt caccggcagt
    47821 catttggcgc ccagcttctt tatttaatcc aatatgtgtt gcataaatgg ttttgaattg
    47881 atgattagcc accatttttc caacaccgcg atcaacaaaa ccagcatcat tacagatcaa
    47941 ggttaaatct tttgtgcctt tgtcaaccag tgcatcaatt aacgcttctg gtgttccatt
    48001 agccataaaa ccaccgacca taatcgtgtc accatcttta atatgactga tagcttctgc
    48061 tattgctatt cttttattct ctttcatacg gttaccttct atcttgttac gatgatactt
    48121 tgaccttggc caccaccaat acaaagcgtt gctaagccat gtctcacatc acgcttagcc
    48181 atttctgcta ataaggtgac taaaatacga gcacctgatg ctccaatcgg gtgacccaaa
    48241 gcaatagctc ctccattgac attaactttt tcattgtcaa aaccaaggtc tcgtgaaacc
    48301 gctaaagcct gagcagcaaa agcttcgttt gcttcaatca aatcaatgtc atcaattgtc
    48361 aactgagcct ttgcaagagc ctttttcgta gcaggtattg gtccgcagcc cataatactt
    48421 gggtctacac ctgcacttgc ataactagtg attttagcta aaataggaag ccctaattct
    48481 tcagcttttt ctttactcat caataaaatt gctgctgctc catcattgat tcctgaagca
    48541 ttaccagcag ttactgtccc ctcatctttg ataaaagcag ggcgtaactt tgctaactta
    48601 tccactgtcg ttccaaattt agggtattca tcttgatcaa cgagtaaagg ttcaccttta
    48661 cgctgaggaa tagtgacagg tgcaatctct tctttgaaac gacctttttc tatggcaagt
    48721 tgggctttac gttggctatc agctgcaaag gcatcttgtt cttctctggt cagtccatac
    48781 tgttgcacaa tattttcggc tgttataccc atgtgataac ctgcaaaagc atcactcaac
    48841 ccatctttaa gcatggtatc tactacttta ctatctccca tacgagatcc ccaacgttgg
    48901 ccttgtaaaa cgtaaggtgc ttgactcatg ttttcggtac caccgactaa aacaatatca
    48961 gcgttgcccg tttgaatctt ttgagcacct aactcaactg cttttaagcc agaaccacag
    49021 accatatcaa tcgtaaaagc aggggtatca taagaaagcc ccgcatttag cgctacttgc
    49081 cgagcaacat tttgacccag acctgcatgt aacacattcc caaagatcac ttcatcaatg
    49141 gcatcacttt taagaccggt atcagctaaa atttttgtaa caactgtcac ccccaaatct
    49201 acggctgata aagatttaaa gactcctcca aaatttccta tcggggtacg ataagcagat
    49261 gtgatcacca cttctttagt catagaaact tctccttttt cattattgaa acgcttacat
    49321 ttttattata taatgtgaac tataataaac aaatatcgtt tttttatata tgctataact
    49381 aaacgttatc gaaagaggaa aatatgaata tctcaagctt ggcttatttt attgagattg
    49441 ttaattgtga ctttaactta accaaagcag cccaaaaaag tcatatttcg caacccgccc
    49501 ttagtagtta tatcaagact atcgaaaaag aagaaggagt cgttttattc cagcgtcaaa
    49561 aagggcgtct agttggacta acctcagtcg gcgaacgctt ttttgaaaat gctaaggtgg
    49621 ttatcgcatc acatgagcaa ttaatggctg atttgcggag tgaatccaaa aaatacaaag
    49681 gagaaatttc aatcggtatt cctcaactca tctctggcat tgttttttct gagctcattc
    49741 caaaactcat cgaagaaaat cccgaagcta aatttcatat tgtagaaacg ggtgcttatg
    49801 aactgcaaaa aaaactgttt ctaaaagaag tcgattttgc gattttatta acacccacta
    49861 cactagatgc tactattgct gatatcgaca ttctcctaag agatcaactc tgcctttata
    49921 tgagtcacaa aacctttcaa gagacgtttg atagtaatcc taacatctct atcaaagcat
    49981 tacatcgtca aaacttagta acttttgata aaacctttat gattaatcat cagcttacca
    50041 ccttatttga agaagcaaat agtcttcctg tagtcaaatg ttattctgcc tcgtgggatt
    50101 ttttattaaa ttgcacgcgc tattcctctt acctaacaat cctaccaagg cctattactc
    50161 attttgctca tatggacggt ttagtggagg tccaactgac cgaacatcca aaatgggaag
    50221 ttgttctagc ctctctcaag cacaataaaa caagccattt aaaacattat atcaagcaca
    50281 ccatcttaga ttatttcatg aaccagcgct tctaattgct tgactcagac cttaaaaaaa
    50341 aacgcctgaa ggaaacaatc ccaagcgttt catgtagtta tttcctaaaa tacaaatagg
    50401 taaatgatgg caatacctgt gaccaccaag acacaaggaa tagtataagc cacaatttga
    50461 ttgaatttta gtttgaagtt tgagagataa gataaggccc aaaaaggaac tatcaagttt
    50521 gttgtggcat ctcctaattg ataagcctgc aaaatcttac ctagatcatt accgacttcg
    50581 atagttgcag ggacgatata tggagcttca atcacaaatt ttgagcctcc tgatggtacc
    50641 gcaatattca gcaaagccga gtaaagataa gcaaagaccg gccatgttgt cccatttgaa
    50701 atagcgacaa agaaatggga aatctctagt cctagacctg tactttgaat gattccaaaa
    50761 ataccagcgt aaaatggaaa ctgaagcacc aagccccaag atgacatgac cccatctttg
    50821 aataaggaac cataatattc tggtccttgt tgaccacaaa gaagcaaccc taagcctaaa
    50881 aataaaaagt taaaactatt gagatctaga ccagacaagc ccaccaccga aaaatgataa
    50941 aggctatagc taacaatggc cccaccaaca agatacatca ctaagcgaga tgcgttcatc
    51001 ttttcagcag gtgtgtttct tgcaataaca acatgtgaag cggtatcaag actatggtga
    51061 tagatctcat catcaagttc catgatttta gtttcatctt ttgggtgcgc caataaagca
    51121 aagcaaagcg gtaccagcat acacaccact aaaagactga taaatggaag attcaaaact
    51181 gattctgtca gaggaacact ttcaggaaca acctgtttat aagcatctgc gacactattt
    51241 cgcaaataat ctggagtagc cgaataaagc accgcagcac cagataaacc agaagtagct
    51301 ggtaaaaagg taaaaaataa agtagcaaca aacaaaggtg tatgcacctt aatccctttt
    51361 tgcctagcct gaacaagcaa ctctttccca aacacaatgg caaccatcat accaagaccc
    51421 cagtgtaaaa agccaaagat agaacctact acaatagaaa aaataaaaat ctgagtcctg
    51481 gtttgaggca gtttggcaag ggacttaaac attttatgag caggtggaga actcgctaca
    51541 gcattccctg tcgcaagtaa aatagtcatc tgcatggcaa aggacaacag cccccaaaaa
    51601 ccatttaccc agccatagat aatcccgccc gtcttttccg taccaataaa gggactatcc
    51661 gtcatcaaca cagacatagt aacgactaaa aaggttaaaa taaaacagat aaaaagcgat
    51721 tctggcatcc atttcataaa gccatcaata tagcgatcca taaacctttt tttggttttg
    51781 atgttattca tgttgtcaat tcctttcaca ttgtccacaa gcacttttgt tcttttgatc
    51841 agtaacctat cgataatact aataagcgtt tctttagttc atttagttat caataagttt
    51901 aaacccacaa aaaacacttt tgttcccttt ttattatgac aacgttttca tagacaaaca
    51961 actatgattt ttttattgct tccataaccc ttatttatag caaaaagaat gacgcttcac
    52021 tcatcaaca
//
LOCUS       DATWVB010000011        49293 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.011, whole genome shotgun sequence.
ACCESSION   DATWVB010000011 DATWVB010000000
VERSION     DATWVB010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49293
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.011"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..844
                     /locus_tag="VCX65_000690"
     CDS             <1..844
                     /locus_tag="VCX65_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053166.1"
                     /translation="NKEMIYINKSGANIQNKVNGTDYQLLDNKVATIYIPDKFKEKKK
                     SIENTVVAEQFTGTKYTKENLAVQIIPNEKKIFYFNENGNEHDENKEASPMANVTDSK
                     GNIVVVLDTDKMVASKDFSLASNIVNSSLFSPEAIKKINDLSLHLNFSINPVDVYQLV
                     KLNIQSLKHQIFLSKVLQKIIYGIVFLLIYQYAQLFISSKQNDYVKKIILGLSKTRIA
                     ISSLKYFIMTIAIVIICTFMVTEQIELLYIGIASLVVLILSTVMSFRKLSKKYTQILK
                     GDEQ"
     gene            841..1462
                     /locus_tag="VCX65_000691"
                     /pseudo
     CDS             841..1462
                     /locus_tag="VCX65_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1459..1950
                     /locus_tag="VCX65_000692"
     CDS             1459..1950
                     /locus_tag="VCX65_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053167.1"
                     /translation="MKKKIYIGLIVIVGVFVVFLSGKQITQKETSNKPVVTLTVYTIS
                     SSDTQKWSKVKQFETKEAIYLVKVKETTSSEEVFSNIIADGMAVGFGVSEEDVKQFND
                     NLCSPVEDAKNNKLIGIEFINFSSVDKGFVVANFDYGKKAFNSQKTENKKLYKKLYEA
                     YKG"
     gene            2154..2684
                     /locus_tag="VCX65_000693"
     CDS             2154..2684
                     /locus_tag="VCX65_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEP5053168.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFLTRLFAK"
     gene            2733..3320
                     /locus_tag="VCX65_000694"
     CDS             2733..3320
                     /locus_tag="VCX65_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEP5053169.1"
                     /translation="MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            3473..4201
                     /locus_tag="VCX65_000695"
     CDS             3473..4201
                     /locus_tag="VCX65_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEP5053170.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     DIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKRFITLIVCLTVETLLFVGGAYF
                     LQLTVWKYLLIPVFLLVLLGTLYWYYQNICYLCPSCHQTFEAKWTEFALAGHTPRTRK
                     LTCSHCHQKSYCLELAKEDTVSRG"
     gene            complement(4258..4557)
                     /locus_tag="VCX65_000696"
     CDS             complement(4258..4557)
                     /locus_tag="VCX65_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEP5053171.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF"
     gene            complement(4750..5124)
                     /locus_tag="VCX65_000697"
     CDS             complement(4750..5124)
                     /locus_tag="VCX65_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5053172.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLESKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            5294..5515
                     /locus_tag="VCX65_000698"
     CDS             5294..5515
                     /locus_tag="VCX65_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5053173.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(5595..7877)
                     /locus_tag="VCX65_000699"
     CDS             complement(5595..7877)
                     /locus_tag="VCX65_000699"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEP5053174.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKI
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDHYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYSHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRASKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(7899..8558)
                     /locus_tag="VCX65_000700"
     CDS             complement(7899..8558)
                     /locus_tag="VCX65_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEP5053175.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
     gene            8724..9920
                     /locus_tag="VCX65_000701"
     CDS             8724..9920
                     /locus_tag="VCX65_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP5053176.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMVIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVLS"
     gene            10422..11270
                     /locus_tag="VCX65_000702"
     CDS             10422..11270
                     /locus_tag="VCX65_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEP5053177.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKVSYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(11606..12502)
                     /locus_tag="VCX65_000703"
     CDS             complement(11606..12502)
                     /locus_tag="VCX65_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEP5053178.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYLGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            12800..13552
                     /locus_tag="VCX65_000704"
     CDS             12800..13552
                     /locus_tag="VCX65_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEP5053179.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDALFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            13537..14487
                     /locus_tag="VCX65_000705"
     CDS             13537..14487
                     /locus_tag="VCX65_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEP5053180.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKAYYPSIVDATVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKGNKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSNHYLNDPFSDCLWRNYSQQTIERSLGWNLDGDWISHTGYTGPFLMLNKKE
                     QTAAIFLTNRTYDEDDKSKWLKERQLLYNALKHDLTTPVS"
     gene            complement(14667..16994)
                     /gene="pflB"
                     /locus_tag="VCX65_000706"
     CDS             complement(14667..16994)
                     /gene="pflB"
                     /locus_tag="VCX65_000706"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEP5053181.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            17203..18297
                     /gene="dinB"
                     /locus_tag="VCX65_000707"
     CDS             17203..18297
                     /gene="dinB"
                     /locus_tag="VCX65_000707"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEP5053182.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDVVEPMSIDEAYLDVTNNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGITMTNLEDKVADISLDL"
     gene            complement(18390..18872)
                     /locus_tag="VCX65_000708"
     CDS             complement(18390..18872)
                     /locus_tag="VCX65_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053183.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSILNVLAIIAIIVFCAQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTMSMVGTILILIQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(18963..21326)
                     /locus_tag="VCX65_000709"
     CDS             complement(18963..21326)
                     /locus_tag="VCX65_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEP5053184.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESGSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QSTNSNPTENSQSDNDDFRLTPENYSTIDSMIGLTESDIALFFQKKS"
     gene            complement(21384..21977)
                     /gene="lepB"
                     /locus_tag="VCX65_000710"
     CDS             complement(21384..21977)
                     /gene="lepB"
                     /locus_tag="VCX65_000710"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEP5053185.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(21988..22890)
                     /locus_tag="VCX65_000711"
     CDS             complement(21988..22890)
                     /locus_tag="VCX65_000711"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEP5053186.1"
                     /translation="MNTLVLKIDAILSKHLKKQLAPYTISSQNIYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHPFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNTISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            23047..23355
                     /locus_tag="VCX65_000712"
     CDS             23047..23355
                     /locus_tag="VCX65_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053187.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            23358..23903
                     /locus_tag="VCX65_000713"
     CDS             23358..23903
                     /locus_tag="VCX65_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEP5053188.1"
                     /translation="MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLARL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            24052..26391
                     /locus_tag="VCX65_000714"
     CDS             24052..26391
                     /locus_tag="VCX65_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEP5053189.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADRNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQ
                     KVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRHKHVKHFAYASQNAGGSGATIVTLG"
     gene            26395..26895
                     /locus_tag="VCX65_000715"
     CDS             26395..26895
                     /locus_tag="VCX65_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEP5053190.1"
                     /translation="MESYEHFYAKLSQPFRKKPQLIILLNVLLKIITGVMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDFPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSVLLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            26976..27290
                     /gene="trxA"
                     /locus_tag="VCX65_000716"
     CDS             26976..27290
                     /gene="trxA"
                     /locus_tag="VCX65_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEP5053191.1"
                     /translation="MALEVTDATFVEETKEGLVLIDFWATWCGPCRMQAPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(27342..27930)
                     /locus_tag="VCX65_000717"
                     /pseudo
     CDS             complement(27342..27930)
                     /locus_tag="VCX65_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(28006..29130)
                     /gene="mutY"
                     /locus_tag="VCX65_000718"
     CDS             complement(28006..29130)
                     /gene="mutY"
                     /locus_tag="VCX65_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEP5053192.1"
                     /translation="MWDNETIASFRRTLLGWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFALYPFATPQKKMLETYLKQKNA"
     gene            29328..29621
                     /locus_tag="VCX65_000719"
     CDS             29328..29621
                     /locus_tag="VCX65_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053193.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            29794..30084
                     /locus_tag="VCX65_000720"
     CDS             29794..30084
                     /locus_tag="VCX65_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEP5053194.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            30106..30597
                     /locus_tag="VCX65_000721"
     CDS             30106..30597
                     /locus_tag="VCX65_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEP5053195.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            30762..31001
                     /locus_tag="VCX65_000722"
     CDS             30762..31001
                     /locus_tag="VCX65_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEP5053196.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(31134..31790)
                     /locus_tag="VCX65_000723"
     CDS             complement(31134..31790)
                     /locus_tag="VCX65_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEP5053197.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQKAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGISLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(31923..32867)
                     /locus_tag="VCX65_000724"
     CDS             complement(31923..32867)
                     /locus_tag="VCX65_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEP5053198.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            33070..35898
                     /gene="uvrA"
                     /locus_tag="VCX65_000725"
     CDS             33070..35898
                     /gene="uvrA"
                     /locus_tag="VCX65_000725"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEP5053199.1"
                     /translation="MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKK
                     GQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVIYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            36014..37087
                     /locus_tag="VCX65_000726"
     CDS             36014..37087
                     /locus_tag="VCX65_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEP5053200.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLEADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRFIKDTSEIDTIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIVASGYRSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIDKASAGMTYSDFDGIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHENPFFGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITETGCQVLTLAPKELIVL"
     gene            37121..37588
                     /locus_tag="VCX65_000727"
     CDS             37121..37588
                     /locus_tag="VCX65_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEP5053201.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGIKKITYKAHYRPHPFAIELMEKKGVAYVQHDVPHIILGGKEGPNG"
     gene            37676..38233
                     /gene="efp"
                     /locus_tag="VCX65_000728"
     CDS             37676..38233
                     /gene="efp"
                     /locus_tag="VCX65_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEP5053202.1"
                     /translation="MIEASKLKAGMTFESEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            38279..38668
                     /locus_tag="VCX65_000729"
     CDS             38279..38668
                     /locus_tag="VCX65_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP5053203.1"
                     /translation="MTTEHIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            38661..39113
                     /gene="nusB"
                     /locus_tag="VCX65_000730"
     CDS             38661..39113
                     /gene="nusB"
                     /locus_tag="VCX65_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEP5053204.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS"
     gene            complement(39254..40219)
                     /locus_tag="VCX65_000731"
     CDS             complement(39254..40219)
                     /locus_tag="VCX65_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP5053205.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINQKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(40224..41663)
                     /locus_tag="VCX65_000732"
     CDS             complement(40224..41663)
                     /locus_tag="VCX65_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEP5053206.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGHYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGA
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYDYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQIPQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTQGQTGIQVVEGQAFGHYYEMRY"
     gene            41905..43788
                     /locus_tag="VCX65_000733"
     CDS             41905..43788
                     /locus_tag="VCX65_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEP5053207.1"
                     /translation="MDNRQIATEVIEALGGRENVRSVAHCATRLRVMVHDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKQGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGHLLQYLVTMLVGLGVAFGIA
                     YTWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLAAVSDPVFSSGAMGQ
                     GLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            44019..47033
                     /locus_tag="VCX65_000734"
     CDS             44019..47033
                     /locus_tag="VCX65_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEP5053208.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQVQ
                     KELSSIDSLHYLSENSKKEFKEELSKAGQESQKVKEILAKAQQADKQAQELAKMKIPE
                     KIPMKPLHGPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKEVDLAFIFHDWTKDYSLF
                     WKELATKHVPKLNKQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDVEHDSIPKVNGEASDENLKRSIDVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAPYIDLLLVQVYGARGEQGEFQNDTKLVTDTPEERWQGYSK
                     YIRPEQYMIGFSFYEERAGSGNLWYDINSRKDEDKANGINTDITGTRAERYARWQPKT
                     GGVKGGIFSYAVDRDGVAHQPKQIAEKDKQNVKNNQPQIPEITDNIFHSDYSVSKALK
                     TVMLKDKSYDLIDEKDFPDKALREAVMAQVGTRKGDLERFNGILRLDNPAIQSLEGLN
                     KFKKLAQLDLIGLSRITKLDQSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPVSL
                     KVSGLTGLKELDLSGFDRETLAGLDVATLTSLEKVDISGNKLDLAPGTENRQIFDTML
                     STVSNHVGSNEQTVKFDKQKPTGHYPDTYGKTSLRLPVANGKVDLQSQLLFGTVTNQG
                     TLINSEADYKAYQNQQIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTLAT
                     DKEETYKVDFFSPADKTKAVHTAKVIVGDEKTMMVNLAEGATVIGGSADPVNARKVFD
                     GQLGSETDNISLGWDSKQSIIFKLKEDGLIKYWRFFNDSARNPKTTNKPIQEASLQIF
                     NIKDYNLDNLLENPNKFDDEKYWITVDTYSAQGERATAFSNTLNNITSKYWRVVFDTK
                     GDRYSSPVVPELQILGYPLPNADTIMKTVTIAKGLSQQKDKFSQKMLDELKIKEMALE
                     TSLNSKIFDVTAINANAGVLKDCIEKRQLLKK"
     gene            47297..48181
                     /locus_tag="VCX65_000735"
     CDS             47297..48181
                     /locus_tag="VCX65_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEP5053209.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFLTTTPEETIART
                     IAYFKAFEADLAGMAIGSFGPIDIDPSSETYGHITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     PHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMTQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            48276..49229
                     /gene="manA"
                     /locus_tag="VCX65_000736"
     CDS             48276..49229
                     /gene="manA"
                     /locus_tag="VCX65_000736"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEP5053210.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATIVLDNMVETTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
BASE COUNT        15187 a         8627 c        10256 g        15223 t
ORIGIN      
        1 aaataaagag atgatttata tcaataaatc gggcgctaat attcaaaata aagtcaatgg
       61 aacagactat cagctgttag ataataaggt agcaacaatc tatattcctg ataaatttaa
      121 agagaaaaag aaatcaattg aaaataccgt tgtggcagaa caatttactg gaactaagta
      181 tacaaaagaa aaccttgcag tgcagataat tcctaatgag aaaaaaattt tttattttaa
      241 tgagaatgga aacgagcatg atgaaaataa agaagcctca cctatggcaa atgtaacaga
      301 tagtaaaggt aatatagtcg ttgtgttaga tactgataaa atggtagcaa gcaaagattt
      361 ttctttggct agcaatatag taaatagctc tctttttagt cctgaagcaa taaaaaaaat
      421 taatgacctg agtctacatt taaatttttc aattaatcca gtagatgttt accaacttgt
      481 aaaacttaat attcaatcct taaagcacca aattttcctt tcgaaagttt tgcagaaaat
      541 tatttacggc attgtatttc tactaattta tcaatatgct caattattta tttcttcaaa
      601 acagaatgac tatgtgaaaa aaataatttt aggcctctca aaaacacgca tagcaatttc
      661 gagtctcaaa tattttatta tgactattgc aatagttata atatgtacat ttatggtgac
      721 agagcagatt gagttattat atattggtat tgcttcatta gtggttttaa ttctttcgac
      781 agtaatgagt tttagaaaat tatcaaaaaa atacactcaa attttaaaag gagatgaaca
      841 atgacaattg aaattttcaa cgttacaaaa aaattcagct caaaaaaaat atttacagat
      901 ttaaatttaa cgtttgaagc tggaaaaagc tatgccttga ttggaggttc tggctctggt
      961 aaaagtactc tgcttaacat tataggaaga ctagaaaaaa ttgataacgg gaaagtttta
     1021 gttgacgaac aagatatttg gaaaataaaa gaaagaactt tctttaaaaa tattatcggg
     1081 tatgtattcc agaattattc tttaatagaa aacaaaactg tatatgataa tttgaaactc
     1141 atcaataaag acaaaaaaaa tatctgctgt acttgaaaaa gtagggctct ctagtggcta
     1201 tttaaatcaa aaaatatatg aattgtctgg agggcaggct cagcgtgtag ctattgcaag
     1261 aatgttaatg aagccacgta aaataatttt agcagatgag ccaacaggag ctttggatgg
     1321 tgaaattgga aaagaaatta ttaatttgtt gttgagcgaa acagccgaaa ataaatacgt
     1381 tattatagca actcatgatc cagctgtata taataaggtt gattttataa ttgatatgaa
     1441 agatataggg agtaagaaat gaaaaagaaa atttatattg gcttgattgt cattgttgga
     1501 gtttttgtag tgttcttgtc tggaaaacaa atcacacaaa aagaaacttc aaataagcct
     1561 gtggtgaccc taacagttta taccatctcc tctagtgata cccaaaaatg gagtaaagta
     1621 aagcagtttg aaacgaaaga agcaatatac ctagtaaagg taaaagaaac tacctcttca
     1681 gaagaagtct tttcaaacat cattgcagat ggaatggcag ttggttttgg agttagtgaa
     1741 gaagacgtta aacagtttaa cgataattta tgtagcccgg tagaagatgc taagaataat
     1801 aaattaattg gaatagaatt catcaatttt tctagtgttg ataaggggtt tgtggttgca
     1861 aattttgact acggcaaaaa agcgtttaat tctcagaaaa cagaaaataa aaaattatat
     1921 aaaaagctct atgaagcgta taaaggatag ctatttatag ttttttgaga gtgataccac
     1981 ttctgaataa taaatgaact aacatggcat accgttttct attcatctaa caatgttttc
     2041 aagaaataat tgatgccttt agcacgactg aaatgaggtc aaattgacag aatactccta
     2101 ttatggtact atttttaata agaatattca gtgatagtga taaagaggaa aatatgggaa
     2161 ttgaaaagac agttagtgaa ctagctgata ttttgggagt gagtcgtcag gccgtcaata
     2221 atcgtgttaa gtctttaccc gaagaagatc ttgacaaaaa tgaaaaaggc gttactgtgg
     2281 ttaagcgcag tggtcttgtt aagctggaag agatctataa aaaaacaatt tttgacgatg
     2341 agcctatcag tgaagaaacg aaacaacgtg agcttttaga gattcttgtg gatgagaaga
     2401 acactgaaat cacgcgcctt tatgagcaac tcaaagccaa agatgctcaa cttgcctcaa
     2461 aagatgagca aatgcgtgtt aaagacgtgc agatcgctga aaaagataaa caattggatc
     2521 agcagcaaca attaactgct aaagccatgg ctgataaaga aaccctaaaa ctagaattgg
     2581 aagaagctaa agcagaagcc aaccaagctc gcttacaagt cgaagaagtt caggctgaag
     2641 ttggccctaa aaaaggcttt ttaacccgct tgtttgcgaa ataatcacaa aaaatgacga
     2701 aggccctatc agggtctttt ttggaggaaa acatgaaaca cttagatact tatattgcct
     2761 ttgatttaga atttaacact gtcaatgacg ttagtcatgt cattcaagta tcagcagtca
     2821 aatatgacca ccataaagaa gttgacagct ttgacaccta tgtttacaca gatgttccct
     2881 tacagagttt tatcaatggc ctaacaggaa tcacatctga caagattgct gcggcaccaa
     2941 aagtagagga ggttatggct gcgtttaaaa attttgtggg agagttacca ctgattggtt
     3001 ataatgctca aaaatctgac ctgcctattc tagctgaaaa tggcttagat ttaagggacc
     3061 aataccagat tgacctcttt gatgaagctt acgatagacg tagcgcagac ttaaatggga
     3121 ttgctaacct tcgtctgcaa acagtggcaa cctttttagg cattaagggt cgaggtcata
     3181 atagcttaga agatgccaga atgacagcag caatctataa gtcattttta gaaacagata
     3241 caaacaaagc atatctcagc cagcaagaag aggtaaccac agataaccct ttcgcagctt
     3301 tgggagactt ttttgactaa gggctctgct atttctaaaa aataacaaaa attcctaggg
     3361 ttagctcttg cttgtaacgc taggtcatgt gataagatag gggcatatca agagggagtc
     3421 gagtgcacac gaatcgtttt tgatcactaa atgatagaaa gaaggtgtgg aaatgtctca
     3481 attctattcg actggagaat tggccaactt agctggcgtt tctattcgaa ctgtccaata
     3541 ctatgaccaa cgtgggattt tgattccgac agctttgaca gaaggtggac ggcgactcta
     3601 tacggattct gatttagaac aattacgcat gatttgcttt ctgcgcgatt tgggattttc
     3661 cattgagcag attcgcaaag tcttagcaga ggaaaatgca gcccaggtgc tggaattgct
     3721 tctagttgat catattgcga ctgccaagga agacttggcc gcaaaagagc aacaagttga
     3781 tatagctgtc aagatacttg acagacttcg aaaacaagac ccccagtcac tagattttct
     3841 gatggacatt tcgcttagca tgaaaaatca aaaagcttgg aaaaaacgct ttattacttt
     3901 aattgtctgt ttgacagtgg aaactctact ttttgtgggt ggagcctatt ttctccaatt
     3961 gacagtctgg aaatatttat taatcccggt gttcctttta gtcttactag gaaccttata
     4021 ctggtattac caaaatatct gttatctttg tccttcttgt catcaaacat ttgaagcaaa
     4081 atggacagaa tttgcccttg caggccatac accacgaacc agaaagttaa cctgctccca
     4141 ttgccatcaa aaatcgtatt gcttggaact ggcaaaagag gacactgtct caagaggata
     4201 agcactaact cataaaaaaa ctagcctgag atccttctca agctagtttt tgttttttta
     4261 gaatggtaat ttaccagcaa aagcgcctaa tgttttctta gtcgcttcat caatttgcgt
     4321 aagggcatca ttaatggctt gagtggtcat gtcttgaagc gtttctacat cttcaggatc
     4381 tacaacagct tctttgaagt caatcccaac caatttttta tcacccgtga aagtggcagt
     4441 gacaaggtct tgagctgatt ttccagtaaa ttgcatagca gccaaatccg cctgcttttg
     4501 ctccatttgt ttctgaagct tttgtgcttg cttcatcatg ttttgcatgt tcatcataag
     4561 actatactct ccttaattta atactaacta ttataacata taaaaagagg caataaaaac
     4621 aatgtcagtt agtagactag cctgtatcag taagaaagtc gctatggata agatggatta
     4681 gcagcaaggg tctggctaat gacagaataa gtctagaaat ggattatttt tgtcatagac
     4741 tagtccgact tagtggttat ctaattcacg atcttcttta gcttgttgtt ctaaaagaat
     4801 ttgtgcgaag tcaacccact tagtgtagtt attttcggat aattgttctg aaatcatcgc
     4861 taactctcgt tgtggcaact gataagagac tcccttactt tctaaggtta aatcttcttc
     4921 cattagggcg gttaaactaa catcaaagat agcagcaata tcacttaata gaccagactt
     4981 tggagtatat tttccttttt cccactcact gattgaagaa gagctttttc gtcctaggag
     5041 attagcaagt tctaattgtt ccatgttctt ttttaatcta aggtacttta aattacttgc
     5101 aaaaaaagtt ttcttggcgg acatattttt ctccttttct ttatataaaa tatgatacca
     5161 taaaagaggt taaagcaaaa ggtatcgtaa aagatggtct aaaaactctc taaaaacttg
     5221 acttcataaa aaccgaagtt tataataaac ttaacatgat taactaatct cattttagtg
     5281 tggagggaaa attgtgacca aatcaacttt aaaagagtta agaacaacaa agaaaatgac
     5341 acagcaggaa ttgtctcact taacaggcat ttctgtcaga acgattgcta ggtatgaaaa
     5401 agatactaaa aagctaaggc gagcaaaata tgagaagcta aaaggtattg cacaagcatt
     5461 agcggtttcc gttgatgata tttttttagg aatagattcg gaatttatga actaagacga
     5521 tcgttttctg tttgctatta gtaagaccaa ttaacaaaaa agtgcttagt tatattgcta
     5581 agcactttta tttgttaatt tgatgctatt ggcacaatca attgagactg actgagatcg
     5641 atagttaaag catagttgct gttgtcacgg acagtatgtt caaaatcggt tgtgtataag
     5701 atgactcgaa gggtatctcc tttttctaga tgatagatag ttggttgcaa aggaagtcta
     5761 acagtcatcc atttattatt aggaatagtt tcaattgacg acaaattatt gcgattttgt
     5821 aaattcatga aacctttcga aataacacgg taagaatctt ctctaaatgg tagctcttta
     5881 aggggttctc tagagaaatt ttgcccattg tcaatacttg attgggtgag agcaatagga
     5941 agatcgccca agcgtttttt cttaccatag tcaaggattt gtgcagatag aagtccttta
     6001 ttttcacttg atttcacttt taactgtagg acaatttcac cgttaatagg taagtcctct
     6061 tccagtaaaa tatcaatcag ggcttgattg gccttgcctt taaagagagc tgctttggac
     6121 gcacggaaat ctttaccgta agctttaaat tcatcttcac catagtgatt atcaattaaa
     6181 agcagttcct gaccgaggtc aagctctttg atggttgagg ttccaaagac tttacgctcc
     6241 tgccagtttt gtgggcaggt gttatcctgc cagatcattt caggaaggct aaaatcatta
     6301 gctaggccta agagtttttg acataaaagg gcattcatgc tttcgcgaaa atcaatggat
     6361 tgccaattat gcatgtaaac atgctcacct tgatgtaaaa agaggtgctt gttgattgtg
     6421 gaaggaagcg cattgaaaat ctcatagacc tgtcttggtt tgacattcca gtcttgtaag
     6481 ccatgactat aaacgacatc acactttatt tgatgagcat tttttaagta attgcggtcg
     6541 tgccaaaatt gattataatc accagattgt cggtctaacg cctgagactg ttggtttagc
     6601 aattcttgat aatgatcatt atggcgaaga taatcgccag ccaataaatt acgcgagtag
     6661 gtgagctcag ttaggacatc tagatcctct ccaggatagc caccaggact acaaactaag
     6721 ccattttcgc ggtagtagtt gtaccaagaa gaaatagctg attctgcaat aatcatggct
     6781 aatccgtcta cgcctgtagt ggctaaacca gtagacatag ttcccaagta ggactttcca
     6841 gtcgtacaaa ctagaccatt tgcccaatca gctctcactt ggtgggtttt tgagtggctg
     6901 gtgtaggctg tggctcttcc atttagccaa tcaataacgg ctttaaagct ttcaatttga
     6961 gcatagtctc cactcgtcat aaagccagtg gaaccagcag ttcccacacc tgaaacatag
     7021 atattagcaa acccacgtgc gaggaaataa tcgttgaggc tataggagtt gatgtagcta
     7081 aagctttcta gattttgacc tataggaagt ttgcaaggct gtgtctcaag aggaataaaa
     7141 tccctgtctt cgacagtgat ttgtctcctt tttttaacga ctaactcttt ttccatacga
     7201 taaagttttt tgtcgttggc tacttcattg ataccttgat ggtatggact aggtgtcatc
     7261 aaagttggta atggtttttg agattgagga cgaatgatat taaccttaat aagatcaagt
     7321 tggccatctt gatcggtatc aagaggtgct tcaacgtaaa caacttctcg aatcagctgt
     7381 gacgtgtcaa aggtagctaa tgatttaccg ttgaagaaat ggtaatcatt gtccatagta
     7441 agcattcctt ggctgaccaa atcatcaatc agggtcatgc cagacttaca acgggtcgct
     7501 aataagtggt ggatatgctt gataatttct gtttcgtcaa agtggatagg aaaggccagt
     7561 ttatcaagga aagcatcggc ctctgtaaaa tcaactccag gaataaagcc aaggacttgc
     7621 agggccagta aatcaaaaac ctctttggat aactcttgct ctgattgaaa aaagctcaat
     7681 gcgtccatgt catttttggc gattagatga cttaaaggat aatcactatc agggtagtgg
     7741 aagaagattt tacgtaaaaa gctttctagg ttagctttgg cagttttttg cagatccaga
     7801 tcaaagccca attcttttaa ttcttcagcc gctctttcta gactagttgg aatataggaa
     7861 aattgattat agcgcatagg agtttccttt ctagtggctt agaaaacgat attatctttt
     7921 aatttatcaa gattggtaat gataatatgt tgtttatcaa tgcgaatgat gtttttttct
     7981 ttcaactgtt ttagaatacg gctgacgctg ctagcggtag aaatgccaca gaatttaccg
     8041 agttcctcat tagtaatgac aaaattaatt aaaatttgac catttggtag ttcttcgcca
     8101 aatagggtca ttaagtcata tatttgagta gaaatggcac cgatacggcc gttagttaac
     8161 atacattgca tttttttcat ggatttttga agacgattat ggtaaaagtc cttcacatat
     8221 ccttgtagtt caatatcttc gtttatatct tttaaaaatg ctgagcggcg aaccttgtaa
     8281 aaactagctt tctctgactc gatgcgaaca ttataaggct ctcccatatc ttttgaataa
     8341 ccagtgttga gaacagaagt aatttcaagt cctgtaacat atctcaaatt aaattccatt
     8401 ccatattttg aaagaacact ctgtttcaca atgccgtctt ttaaaatata agtgaagtcc
     8461 tcttcgagac tttcaaaagt caagtacttg tgataacttt tttcaatgat aggaaagtta
     8521 tgattatcaa tataccgttg caaaatgtga tgattcacgc ttttctccaa atattctttt
     8581 accaatgtat aatttgtatc ttcaagagaa attaacattt gctaatgccc tttgatagta
     8641 acacttatat tataccattg aaatatatta tattctgctt tttttgtaaa atgtttatga
     8701 aaatagagag gagttcattt tcaatggaag aaaaattgtt taacaaacat tttgtggcca
     8761 tcacagtaat aaactttata gtctatatgg tctactatct ttttacggtt attattgcct
     8821 ttgtggcgac tagagagcta ggagctcaga ctagccaggc aggattggca acagggattt
     8881 atattctagg gactttatta gcccgtttga tttttggaaa gcagttggag gtgtttggtc
     8941 gtcgtttggt tttaagagga ggtgctattt tttacctctt aacgacctta gcctactttt
     9001 atatgccaac gattagcatg atgtacttgg ttcgtttctt gaacggattt ggttatggtg
     9061 tagtatcaac tgcgacaaat accattgtaa cagcctatat tccagctcgt aaaagaggag
     9121 aaggaattaa tttttatggc ttgtcaacca gtctagcagc agctattggc ccttttgtag
     9181 gaacctttat gttggataat cttcatattg attttcgcat ggttattgtc ttatgtagcg
     9241 tcttgattgg gtgtgtggtt gttggtgctt ttgcttttcc agtcaaaaac atgtctttaa
     9301 atgcggagca attggctaaa accaaatcgt ggactgtgga tagtttcatt gagaaaaaag
     9361 ccttgtttat cactgcaatc gcctttttaa tggggattgc ctatgcttca gttttaggat
     9421 ttcaaaaatt atacacgtct gaaattcatt tgacaacagt aggcgcttat ttctttgtgg
     9481 tctatgcctt aatcattacc atcactcgtc cagcaatggg acgtttaatg gatgctaaag
     9541 gcgataaatg ggtcttgtac ccaagttatc tttttttagc aatgggactc ttcttgctag
     9601 gtagtgtatc gtctggagga agctatttgc tttcaggagc cttgattggc tttggttatg
     9661 gcacttttat gtcttgtggt caagccgcct ccatacaagg agtggatgag caccgcttta
     9721 atacggctat gtctacttat atgattggtc ttgatttagg tttaggtgct gggccttacc
     9781 tcttgggctt gattaaagat ttggcacttg gtagtggtgt ggcttccttt aggcacttat
     9841 tctggttagc tgctgtgatt ccactgattt gtaccttgct ttacttatta aaaacaaaga
     9901 caagacaggt tttgtcttaa ggacaagaaa aggagtttag tcttatactt aaatacaaac
     9961 gtatcttaac agctgtagat agttcctatg agccgggatt agctgtgggt aaagccatta
    10021 ctatagcgct ttgaaataat tctagtttgc tattcgtaca tgtcaataaa aatgactcgc
    10081 aaaagccatt cgtgaaagag aaaatgtggc cttattttta gtaggtacaa ttggattaag
    10141 cacgtttaga tacatgacaa ttggattaac atcagaatat aggctttgtc atgttaagat
    10201 tgatctgttg atcgtgagag ctaataaaaa atgttataat actatgaaat aaagtgataa
    10261 agataaggcc ttttatggtc cttttcttta ccgcttttat tattgtgtga aaataacact
    10321 taatgatcat tttatttatt attttattac ctttacattc atcaataagc ctgttaaaat
    10381 ggtatttgtt atattttatt atttggagga aaccagaaaa catggaaatg acatggactg
    10441 tgaaatacat cacagaattt atcgcaacgg cttttttgat tattttgggg aatggagctg
    10501 ttgctaacgt cgacttaaaa ggaacaaaag gacataactc aggttggtta gtgattgctt
    10561 ttggctatgg cttaggagtt atgatgccag ctttgatgtt tggtaatgta tctggaaacc
    10621 atattaatcc tgctttcaca gttggactag cagtatcagg cttgttccca tgggctcacg
    10681 tcttacaata cgttgtggca caattacttg gagctatctt tggtcagttg gtagtggtaa
    10741 tggtttataa accttacttt atgaaaactg aaaatccaaa tcatgtttta ggctcattct
    10801 caacgatttc atctcttgat aatggtcaaa aagacagcca taaagtctct tatatcaatg
    10861 gtttcttaaa cgaatttgta ggttcatttg ttcttttctt tggtgctttg gctttgacta
    10921 aaaactactt tggggtagag ttagttggta aattgattga agcaggttac gaccaaacaa
    10981 ctgcagcaac acaaatttca ccatacgtga caggctcatt ggcggttgct cacattggta
    11041 ttggtttctt agttatggtc ttggttactt cattaggtgg accaactggg ccagcactaa
    11101 acccagcgcg tgattttggg cctcgtttgt tacaccactt cttaccaaaa tcagttcttg
    11161 gtcaagccaa aggtgattca aaatggtggt atgcatgggt tcctgtagtt gcacctatct
    11221 tagcggcgat agtagccgta gcagcgttta aataccttta tatcagataa aaaaagaact
    11281 aaagcttctt ttagactcaa gacaagctcg cttaaggaac ttgtcttttt tatatgagtt
    11341 aagcgaaatc taatgcaaac ttgactgtct tgtatagcgt attttgtaaa ttttactaga
    11401 cttcttgtaa aaaagcctct cctcagataa gatgactaat gcctctaaac ggtgttacaa
    11461 ataaacgagg catccctaac ttcctttatc tggtgttgaa actattttgc acggactaaa
    11521 tcactgatag agtaaaaaac gatttttcat ttttgttgta aaatattaaa aacgtctctg
    11581 gttagtgatt cccagaaacg ttatcttatc tatttgtttg ttgcttatga gaggtaaagg
    11641 aggaacgaat cagcattcca ccagtgaaga aaacgatagc gatgaccaga agtttcaagc
    11701 tattaatatc taaatttgtt aagaaaaaca cagctagtaa aacgccaata ataccaccag
    11761 aaacaattcc agcaaaacca tcccaactga cacggtttgc tttgataaac tggctactag
    11821 aagctgtcat aatcatagct gcatctagca tcataacagg catagcaact gttgggctaa
    11881 gacccattaa tgaaaagaaa atcaattctg gagcataatt gcctaacccc atagtcatca
    11941 agactccaac gataaaatta aaaccaattc caacaaaaag ccagatgcca tggaggccat
    12001 gaatggtgtc tgaaaggtgt tctcctggat ggtagattat tctaatgatc atgattatag
    12061 ctgctatgat taaaagacta ccaaggattc gttggacagt tggagcatgc cagttttttg
    12121 taatatgagt ccccaaataa gctccaataa aggctgctgc agccatagca agtaaagtta
    12181 gaacctcaac ttttacgaca aaaataaagc aaagagattg aatgagcacc ggaagcacat
    12241 gagctacggt catagtgcca ggcaattgtc tatcgtcagt gactaattta gttaacttaa
    12301 agcacgttgt ggtagtagca aaagacccta tcccaagggt gtcaagggca tctgttagca
    12361 ggccaatcca aaaccccgtc caaaagcgtt taaaaggatt gatcttattt tttttaagat
    12421 gttttactaa cataaagaaa ataaaaagca ttgccgaaac tagcaaagct tgtatcagtc
    12481 taaggataag catttcgttc ataaagacta gtttacaaaa aaaaacctta gccgtcaacg
    12541 tgatttactt cattaaaaca tgccactatg cttagaagag ctttggttcg atgtattttg
    12601 ttaaaattaa gctaaaatat taatattgca tgaaagggga cgccttcctt tttcccttac
    12661 tgagcttagc tgttattgta gtgaatgttt aaaaggctag tttgtcgctc tttatcaaaa
    12721 atctagtagg atgaatacgt ataatttctt gtcaaataga ggaattttgt ctataatagc
    12781 agaggattag gaggaaatta tgactttaat ggaaaatatt acctttaaaa ctccagtatt
    12841 acgcgttaat gatcgcgacc ttaatattgc attttatcaa aataatttag ggcttcgttt
    12901 agtatctgaa gaaaatgcga ttgctatctt ttcatcttgg ggagaagggc aggaatgttt
    12961 tgtaattgaa gagtcacctt cagttagaac gcgtgcggta gaaggcccta aaaaggttaa
    13021 tacgattgtc atcaaaacaa atcaacctaa agaaatcgaa caattattag ctcatggagc
    13081 acattatgac gctcttttta aaggtcaaaa tggctatgcc tttgagacta tttccccaga
    13141 aggagaccga ttcttgttgc atgctgaaca agatattaaa catctccaag gtactgattt
    13201 accatcgctt gaaaaagatg caacttttaa aggtttaact caatttaagt ttgatattat
    13261 tgttttaaat gttattagtg aagaacgctc aaaagctttt tatcgggatc tgtttagtga
    13321 tcagttacct attactatgg attttattca agaagaaggt cccgatttgg caattgatcc
    13381 ccatattgct tgggatttag aaattttaga atttcaagtc tcaaaggact atgatatgaa
    13441 ggtcctaaaa gcaactttag aagaagacgg gcacaaggtc tacattgata aaaaacacaa
    13501 agtattggtc ctttctgatc caagtcagat cgaagtatgg tttacgaaat gactttggca
    13561 gtcattaaat gtattgaaaa ccatcttcac aaaaaagtat acaaaggggc cagtctggct
    13621 ctctttcaat ctggtcgatg gcaagaatac catatcggaa caattgatgg aagacgacca
    13681 gttgatgcta acttagttta tgacttggct agtgtttcaa aagttgttgg tgtggccaca
    13741 atatgcaata ttttattgaa taatggtacg ttagcattag atgatccctt aaaagcatat
    13801 tatcctagta ttgttgatgc gactgtcact attcgacagt tattgactca taccagtggt
    13861 cttgatcctt atattcctaa cagagatgtt ttaaatgcac aacaattaag aaaagcactt
    13921 aatcatctta ctcaaaaagg aaataaaaac ttttattaca cagatgtcaa tttcctcttg
    13981 ttaggcttta tgttagaaga gctctttagt gaatctttag accagatatt tgacaagact
    14041 atctttactc cctttgggat gtatcatacg tcttttggcc ctcgtccaga agctgtacca
    14101 acattaaagg gtgtgagtga tggggaagtt catgatccca aagcaaaaat cttaaaaaaa
    14161 cattctggat ctgcggggct attttcaact cttgcagatt tagaaagttt tagcaatcat
    14221 tatcttaatg atccattttc agattgtctg tggcgcaact acagccaaca aacaattgag
    14281 cggtcactag ggtggaattt agatggcgat tggattagtc atacaggtta cacagggccg
    14341 tttctaatgc ttaataaaaa agagcaaacg gcagctattt ttttgaccaa ccgtacttac
    14401 gacgaggatg ataaaagtaa atggttaaaa gaacgtcagt tgctttacaa tgcactaaag
    14461 catgatctga caacacccgt atcgtaacgt ctaaaggggc agttttagcg atcttattac
    14521 tgtttttaaa gtttcttcta aaaaatagcc atttcatttg tctgatgaga ttagagtgat
    14581 tataagtgaa aaaagaacag ccatctcatt ttgaatcaaa tgagatggct gttctttttt
    14641 ataagttatt gatcatttag atactactat ttacttgaaa tagcttcagc ggcatcatcc
    14701 attgaaagca cttcgtggaa gacacgttga gtcaattcag ttttttgttc tggtgtaagg
    14761 tatttggtgt tgacacagta accagagata cgcacgataa cgtcttcgcc gttcatgatt
    14821 ttgtcataaa catcgttaag gtccataacg ttcaagttaa cgtgctgacc accattttca
    14881 aagtaaccgt caagcactgt taccaagttg tcaacttgtt cgtcaaatgt tttaccaaga
    14941 gcacgaggtg atacttgagt agtcaatgag ataccatcgt tagcatgtga gaattccagt
    15001 ttagcaagtg agttaaggtt ttgtaaccag ccaccttttg ctttgttaga tgggttagca
    15061 cctggtgaga agaattccac ttggctagtg ttaactgtac catcttcgtt taagaagacg
    15121 ccgcggtgaa ctggagagtt accagtttgt ttagagtaag caacgtttga agtgatggta
    15181 agaagtgata ctgaagcctc agcattcttg taaagtttgt ggcttgcaag acgtgtgtgg
    15241 taagcttcca tcaaccattt cgcgatgtca tcaacacggt cgtcatcttc accgtaacga
    15301 gggaagtcac ctgttacttc gtagtcatag atgtagccat tttcatcgcg gatagtttta
    15361 acagttgcgt atttaatagc tgacaaggta tcaactgtgt tagcgaaacc acagataccg
    15421 aatcccatgt tagcacgttg gtgtgttggc aagaaggcca tttgaactgc ttcgtagttg
    15481 tatttatcag tcatgtagtg gatgatgtta agcgcatcta cataagtatc tgtcaaccag
    15541 tcaagagatt tctcaaagtt agccataact tcgtcgtact caaggacttc tgatgtgatt
    15601 ggttcaacaa cgttaaacac tttgtagtct ctgtgaacat catcgtaacc accgttaaga
    15661 ccagtaagaa gggctttgag aacgtttaca cgagcaccga agtattggat gttatgacgt
    15721 tgttcttcat tttctgggtc aagtggtgat acacaacatg aaatacatga catttcacca
    15781 taaccttctt tagccattgt tgtcacacct tcatattgga tagaagagtg tttgtggctc
    15841 attttcatac agtagcgacg gaatgtttct ggcagttggt cagtccaaag aactgttaag
    15901 tttggttctg gagagttacc gatattatca agagtgttta agaaacggta gtccatctta
    15961 gtcacacggt gacgaccgtc gttacccata ccagccatag aagttgtgat gaatgttggg
    16021 tcacctgagt aaagggcatc gtaagcttta gtacgaccaa attttacggt acggagttta
    16081 aggacaaaat catccacaaa ttcttggatt tctgattctg taaaggtacc gcgagcaagg
    16141 tcacgttctg caaagatatc aagaacgatt ggcacacgtc caagagaagt agcagcaccg
    16201 ttgatcacac gacatacagc catgaaagcg atgtttaccc attggatagc ttctttaacg
    16261 ttttgtgctg ggcgacgaac atcaactccg taaaggtcac caagtttaac cacttcacca
    16321 agagcttggt attgaaggtt aacttcttcg cgaagacgaa tggattcttc atcgatttca
    16381 gtgatagcat tccagtcatt gactttttct tgcatcaagt agtcagcacc gtaaagagca
    16441 agacgagcgt aaacaccgat gatacgtcca cgtgagtaag catctggaag accagttaca
    16501 gtgtgggcat gacgagcacg acgaatattt gaagtataag cgcggaagat accgtcgtta
    16561 acagttgtca cgtacttagt aaagatttcg tgtactgctg ggtctggttc atagccgttt
    16621 tctttaaggg tcgtttccgc catacggata ccaccttttg gcatgaagtt caatttgaac
    16681 aattcatcgt tttgaatacc ataaattaat tcattttctt tatcgatgaa accagcagga
    16741 atgtcagcaa ttgaagttgg acgagtatcg tatgggaaac gtgtagcttc atagtgtgct
    16801 tttgtttctt cgataacttt tttgatgtga agtgaacgtt cagtagcacc agccaagaaa
    16861 gattcatcgc catcgtatgg ggtgtagtta gcttgtacaa aacgtgagac acttgctttt
    16921 tctttccagt cagttccttt aaagccttcc caagcttttt cgaaaacatc tgtattggtt
    16981 ttaacagttg ccataaattt ctccttaaat tctagtaaca aagcgatctg ttacatttac
    17041 aattctaagt ttaacatata ggaaacgttt tcccaagcaa aattcttgac aaaattaaga
    17101 ttcttttata atacagattg ttgaaacagt cacaaactgt attagaatgt atttttttgg
    17161 ctttagatag cctaaaaggt ataatagaga aaggagggac ttatgcttat ttttccactg
    17221 attaatgaca cgtcacgaaa aatcatccat attgacatgg atgccttttt tgctgcagtt
    17281 gaggaaaggg ataaccctgc tttaaaagga aagcctgttg tgattgggaa agatccaaga
    17341 gaaacaggtg gtcgcggagt tgtttccact tgtaattacg aagcgagaaa atatggcatt
    17401 cattcggcca tgagctctaa ggaagcttat gagcgttgtc ccaaagccat ttttatttca
    17461 ggaaattatg aaaagtatcg aacagttggg gaccagatcc gccgtatttt taagcgttat
    17521 actgatgtgg tagagcccat gtccattgat gaggcctatc tagatgtcac caacaataag
    17581 ttgggtataa aatcagccgt caaaatagcc aagctgattc agcatgatat ctggaaagaa
    17641 gtaggattga cctgttcagc aggtgtgtct tataacaaat ttttggctaa attggctagt
    17701 gattttgaaa aaccccatgg cctcacccta gtcttgaaag aagatgccct gtgcttttta
    17761 gccaaactcc ccattgaaaa gtttcatggt gttggtaaaa aatcagttga aaaactgcat
    17821 gacatgggga tttatacagg acaggatttg ttggcagttc ctgaaatgac cttgattgat
    17881 cattttggtc ggtttggttt tgacctttac cgtaaagcga gaggcatcag caattctcct
    17941 gtcaagtctg atcggatacg caagtcaatt ggcagtgaga gaacctacgc taaactgctt
    18001 tatcaagaaa cagacatcaa ggcagagatc agtaaaaatg ctaagcgcgt ggccgctctc
    18061 ttacaagacc ataaaaagtt aggcaagact attgtactca aagtgcgtta tgctgatttt
    18121 accaccttga caaaacgtgt caccttgcca gaattaacca gaaatgccgc acaaattgag
    18181 caagtagctg gggatatttt tgacagctta agcgaaaatc ctgctggtat ccgcctgtta
    18241 gggataacca tgaccaattt ggaggataag gtagctgata tttccttgga cctataggag
    18301 aaagagtgct ctatccgtcc gcctcatttt ggagaaaaaa gaagctgatt agggatttcc
    18361 ctaatcagct tctttggtcc attattttat tacagcatag cttggtctgt atcatcacct
    18421 ttttcgttaa gggttttagc cttgtaaaaa gcaaagccat aaagagcagc ttgtataagg
    18481 ataaggatag ttccaaccat tgacatggtt gttgtgaact ggttaaccaa gccgataaca
    18541 gaaaggataa ggcctaagat ataaggaata taactaaccg ttagaccttg ttttaattta
    18601 gataagtttt gagcacaaaa gacaatgata gcaataatag caaggacatt taagatagat
    18661 aagaaaatca taaatggtgt catgctgctt tgtagctgtg ccaattgctc agttgttaat
    18721 tgggcccgaa atgcttcatt cttgagttgg ctttgtaagt agaaaatccc tgcaaatccc
    18781 attaatgaca gtacaactcc aagcccgttt agaataataa tggcaatagt agacgttttg
    18841 agtgcctgac gcactttttc ataagaaatc atataatcct cctagagttc ttaatccgaa
    18901 attgtacaat gtgtttaata caaaaatatt ataccataga ttaatcaaaa atgtccgttt
    18961 ttctaggatt ttttctggaa aaagagggca atatctgact ctgtaagccc tatcatcgaa
    19021 tcgatagtcg aataattctc aggtgttaac ctaaaatcat cattatctga ctgagagttc
    19081 tcagtggggt tagagtttgt tgattgagag gaggctaagt cggattgttc ttggaagcgt
    19141 tcgatcaagt aggtttggcg tttatcgcct tcgtgtttaa tagcatactc aaaggcagta
    19201 tattctccca acagaattaa cttactttta gaccgagtaa tggccgtgta aatcacattt
    19261 cgttgcaaga gtcggccgct ttggcgtgtg ataggtaaaa tcaccacttg aaactcactc
    19321 ccttgcgatt tatgaatgct catggcatag gccagggtta attttagcca ttcatttcta
    19381 gggtacgtga cttcgctacc gtcaaaatct aagattaatt cgtcttgctt agattcggtg
    19441 tatttagcag gaatcaaatc tgtaatataa ccaatatctc cgttaaagac attcaactga
    19501 gcatcgttga ctaagtgcag gactttatca cctttacgaa aatgcgtatc attgaacaga
    19561 aattctgttt gtccttgcaa gggattgaga agttcttgca tgagttgatt aagatgattg
    19621 atgccagctt gtcctttgta cataggcgct aaaatttgaa tttcctcagc agggatgcca
    19681 cttttaatag cagataggac aattttttga atcatgtcag ggataaaggc tgcttgggct
    19741 tcaaaataag aacggtcagc ttttttatca cgaaagtcag cagctaagat tcctcgacgc
    19801 atctggtctg ccaaattgac aatagtagat tcttgggatt gacgaaatat cttttgcaag
    19861 gcgatttggg gcaggctatt gacttttaaa agatctgaca ggacttgacc gggtccaacc
    19921 gaaggaagct ggtcactatc tccgacaata atcacttgag ttgttgaatt aatagctcct
    19981 aacaactggt tggcaagcca ggtatccacc attgaaaatt catcgacaat cagcaggtcg
    20041 cagtctagat aatcctccat ggcttggtaa tcgttgtcgc cattgaggcc taagtgcctg
    20101 tggatggttg cgctaggaag tccagtcaac tcattcatgc gacgtgcagc ccgacctgtt
    20161 ggagctgcta acaagatagg aaggtctttt ttatccaaat caatctgatg caggttcgcg
    20221 taagcctgca aaatgcctcg aataacagtt gtttttcctg ttccgggacc acctgttagg
    20281 agaaagacct tgctggttaa ggccttagta atggcttctt gctgcacttg gtcataggtg
    20341 atggcaaagt ctttttgaac ggcttggatg gttgtttgaa tggtatcatg actaaatgac
    20401 tgacttaaag gggtatctaa gagacgagag atgttgttag caatcccttc ttcagcaaaa
    20461 taaaggctag catcaaacag tttggtgtca ctgtttttga ttttgccctc tatgatcaac
    20521 tcgcttagtt gttcagccac agcagcagga tcacattcta cttgacgtgc atcttcaagg
    20581 agtgtaatgg caaagtctaa taattgtcgt gcttgaacat aagtatctcc tcgattgatg
    20641 gattcttcca agagacagtg aaggagggct gcacgaaaac gtttcggaga gccgctttca
    20701 atccctaagt tttcagcgag agcatctgcc attttaaacc caaaaccttg tagatcttcg
    20761 actaactgat agggattttc tttaacaagg tcaagagcct cttctttata cttttcaaac
    20821 gcttgaaagg caaaacggtt gctaaggcca agttcgacga gaccagcaat cagttgctct
    20881 gtgccgtaat tcaattttag tttagcgaca aaggcttgac gattagcctt agataggcca
    20941 gagatagttt ctaatttgct tgggtcttct aaaatatggt caatggtatt atgaccatat
    21001 agtgcaatga ttttctccgc tgttttttta ccaatcccct taaaatggtc gctagagaaa
    21061 taattaacca aaccagatga actaggtttg attttttggt aacggcttag tttgagttgc
    21121 tgtccatatt tagggtgctg ggtcaattct ccccaaaagg tgtagtcatc tccttcaata
    21181 atgtcagcca tcgttcctgt gataatgatt tcaaagtcgt caatgtcact gtctgtatcc
    21241 tcaatggcaa ggaggagaat cttaaagaaa ttagcctggt tttcaaaaat gatacgatca
    21301 acagtacctg taaaaacgta ttccatagta actctttcta tttatacaag ataactgaaa
    21361 acctgcccaa aggcaggttt tttctaatta aagacggtca ttttattgag tggccaaaaa
    21421 cgagctttca cttcaccgat aaggttttct tttttgaaac taccaacttc gcgactatcc
    21481 ctggaaacaa tacgatcatc accaagaaga aggtattctc cttttggaac actcatctca
    21541 aagcgtgttt gtccctcaga attagttgta aaagcatcag atgtttctgc taactgttgg
    21601 aatagggtat tataggcgta agttttttgg agtttatcgt ttttaaattg ttttagatac
    21661 tcagccaaat acggctcaac tgttttttta ccattaatat aaagtgtgtc atcattataa
    21721 gaaatggtat cgcctggcaa tccaataact ctttttacga tttctttctt ttgtccattt
    21781 tcttcttcct gagcaactac aatatcaaag cgatcaatcc tagcttgatt aaaaacgata
    21841 aggcgttcgc catgagctag agttgggtcc atagaatggc cgtctacttt aacagcctgc
    21901 cacaaaaaaa gacgagatag accaaagaga attaaaaaga gagtgaatgg gccccattct
    21961 ttaataaact gtttcatatg attcctttta tttagtgaga agcgcttgcg ctttgtgagt
    22021 gttggcgaag tgaagtttag cactatattc taagctagac ataccataag cggctaagag
    22081 ttggctagca actttatctg aagctgaacc agcaccgctt gggagttggt aacctaaatc
    22141 ttgacctaat tgatcgagat tgtctaaaaa tagatttcta gcaatgatag agctaacagc
    22201 cacagccaaa tagtgacttt ctgccttttc ttgaaaggtt agaggatttg ggaaatggtt
    22261 tttttccttt tttagatgct tttcataatt tgattggcta gtgaaagcat caataacaat
    22321 ttgtttaggt tgaatgcctt tttgtaacaa caaaaaaata gcttggttat gaagagcaac
    22381 tttgatagaa atggtattat atggtttact tttaccaacc aattcgttat attttttagg
    22441 tgataggaga agtgattgat gaggtatttg tttctctaac agaggcgcaa tctgttgaat
    22501 ggttttatcc gataattttt tagaatcatc aaccccaagc tttttcagga agggatgatc
    22561 tttaggatcg acaaaacttg ccacaacagc aatcccacca aaataagagc cattacccac
    22621 ctcatcactg ccgattatag gtatatcttg gctattgttg cttgcttcaa aaactgtctt
    22681 agctactgga agattaagct cttgagctaa agcatttgca ccgtttccct ggagaactaa
    22741 ttttccggat ttgtacagca aaacagtaac cccatttttt ttagcagcaa aggctacata
    22801 gatattttgg ctactgatgg tgtagggggc tagctgtttt tttaaatgtt tactcagtat
    22861 agcatctatt ttcaaaacta aggtattcat aataattatt ttaacataaa atagttgact
    22921 atggttaatt cataagttta tttaacaaag aaaacagaga ctcgaatgtt tagacgggtt
    22981 agggcaatgg tgttgactat tttacgaaag tttcatttta cggtataatg ctaatgaggt
    23041 gaccctatga aaagtattaa tcgctataaa ttcacctttg gtgaaaaaac attaacattg
    23101 acaactgaca aagacaatct ctttatggaa gaagttgagc gggtagctaa agaaaagtat
    23161 caggctctta aaaatcattt accagaagct gatgacgaga caatcgctat tttaatggct
    23221 atcaatacct tgtcaacaca attaagcaga gagattgcca ttgaaaaaat ggaagctgaa
    23281 attttagatt tacgtcaaaa aaccttggtt ggtcttcaag aaaaagctaa tcaaatagat
    23341 gtgaatgagg tttaatcatg ttatctttat tgatagtgct tgttttaact tggaattttt
    23401 atattggtta tagtagaggt attattcttc aatcgtttta tgtcttagga gccctacttt
    23461 ctcttttggt agctaatcga ttttatattg gattagccca taagctaacg ctttggattc
    23521 cttattctaa cccggtagaa ggaacatcag tctttttctt taaatcagtt gatatctttg
    23581 ttttagataa ggtttattat gcaggccttg ccttttttat cattttctta ttggggtatg
    23641 cactgagtcg ctttcttggg atttttgttc atttcctttt gctagattat tttgataacc
    23701 agtggacaaa atgtttgagt ggcggactag cgcttctagt atcgcttctt tttttgaaca
    23761 tgttactgtc tatttttgca acggtcccta tgcctttttt acagcactat ttgcactcta
    23821 gttttcttgc tcgtttggtg attgaacacc ttccaccatt gacaataatt attcaaaaat
    23881 tgtggattca agccattatt tgatatcgtt ttgtgactaa tataagaacc tggagtgagt
    23941 ttcaccttta ggttctttat ttacgagaaa ctgtttagaa ataaagagaa cgcatgggaa
    24001 cttagtgact ttcttgccac attttccatc attttaggta taatgaagag tatgaataac
    24061 aagattttag agcagttaga atttaacaaa gttaaggaat tgctattacc ttatctcaag
    24121 acagaacaat cacaagaaga attattagag ctggagccga tgacggaggc tcctaaaata
    24181 gaaaaaagtt ttaatgaaat ttctgacatg gaacagattt ttgttgaaca tcactcattt
    24241 ggcatagtca gcctaagttc aatctctgag agtttaaaac gcttagagct ttcagctgat
    24301 cttaatattc aagaactttt ggctatcaaa aaagttttac agagttcttc ggatatgatt
    24361 cacttttatt ctgatttgga taatgtttct ttccaatctt tggatcgttt gtttgaaaat
    24421 ttggaacaat tccctaatct gcaagggtct tttcaagcta tcaatgatgg tggtttttta
    24481 gaacattttg cgagtccaga attagagcgt atccgtcgtc aattaacaaa tagtgaacga
    24541 cgggttcgtc agattttaca ggatatgctt aaggaaaaag cagagctttt atcagagaat
    24601 ctaatcgcta gtcgtagtgg acgaagtgtc ctaccagtaa aaaatactta tcggaatcgt
    24661 atttctggtg tggttcatga catctcttct tcaggaagta ctgtttatat tgagcctcgt
    24721 gctgtagtta cactaaacga agagataact cagcttagag ctgacgaacg ccacgaagaa
    24781 ggtcgtattt tacacgcatt ttcagacttg ttaagacctc atgtcgccac tattagaaat
    24841 aatgcatgga ttcttgggca tcttgatttt gtaagggcta aatatctttt tatgtctgat
    24901 aataaggcga cgatacctaa gatctctgat gacagcacgt tagcattaat caatgttcgt
    24961 catcctcttt taagtaatcc tgtggctaat gacttacatt ttgatcacga tttaactgca
    25021 attgtcatca ctggtcccaa tactggtggt aagacgatta tgctaaaaac actcggttta
    25081 gcacaattaa tgggacagtc tggtttgcca gtattagcgg ataaaggtag taaaattgca
    25141 gtatttaaca atatctttgc agatattggc gatgagcaat ctattgaaca aagtctatca
    25201 actttttcta gtcatatgac gcacatagtc agtattttaa acgaggctga ccgcaatagt
    25261 ttagttctct ttgatgaact aggagcagga acggatcctc aagaaggtgc tagtttggct
    25321 atggctattt tagaacacct taggttaagt catatcaaaa cgatggcgac cacgcactat
    25381 ccagaattaa aagcttatgg gattgagaca aattttgtag agaatgcgag catggaattt
    25441 gatgccgaaa cgcttagccc cacgtatcgc tttatgcaag gagttcctgg acgatcaaat
    25501 gcatttgaaa ttgcttctcg ccttggttta gctccattta ttgttaaaca agctaagcag
    25561 atgacagatt ctgactcaga tgttaaccgt attattgaac agttagaggc acagacactt
    25621 gagacacgta gaagactgga tcatattaaa gaagttgaac aagaaaatct caaattcaat
    25681 cgtgcggtta agaaactcta taatgaattt tcacatgaac gcgataaaga gttagaaaaa
    25741 atctatcaag aagctcaaga aattgtagat atggctttga atgagagtga tactatctta
    25801 aaaaaactca atgataagag ccaattaaaa cctcacgaaa ttatagatgc taaggcacaa
    25861 ataaaaaaat tagcacctca agttgattta tcaaaaaata aagtcttaaa taaggctaaa
    25921 aaaatcaaag cagctcgtgc ccctagaatt ggtgatgata ttatagtgac tagttatgga
    25981 cagcgaggta ccttaactag tcaattaaaa gatggccgtt gggaagcaca agtgggaatt
    26041 atcaaaatga cattaacaca agatgaattt agcctcgtta gagtccaaga agaacagaaa
    26101 gtcaaaaata aacagattaa tgtggttaaa aaggctgata gttctggacc aagagctcga
    26161 cttgatctta gaggtaaaag atacgaagaa gcaatgcaag agttagatca ttttattgat
    26221 caagcattgc ttaacaatat gggacaagtt gatatcattc atggtattgg tacaggcgtt
    26281 attcgtgagg gagtgacaaa atatcttcgt cgtcataagc atgttaagca ttttgcttat
    26341 gcctcacaaa atgcaggggg atctggcgcc acaattgtaa cgttagggta aatgatggaa
    26401 tcatatgaac acttttatgc caaactatct caacctttta gaaaaaaacc acagttaata
    26461 attcttttaa atgttttact aaaaataatc acaggagtga tgtacatact ttatccatct
    26521 tttctgatat ttacgctttg gcaagggatg acatttcaat tatggttaag gttattaatt
    26581 attcctgctg ttggctttat agctttgtct tacattagga aacgctttga ttttccacga
    26641 ccgtatgaaa aatggaatat taaaccttta attgataagg atacaaaggg aaggtcaatg
    26701 cctagcagac atgttttttc agctacgatg attagtatgt gtttgttacg atattatgtt
    26761 tactttggaa tagtttgttt aatattatcg gttttattgg caatttgccg tgtgatagca
    26821 ggtattcact atcctaagga tgttattgta ggttacctta ttggcttgat gttagggctt
    26881 tgtttattga tttagcgagt tcgtagcaaa tagtttcaaa aacaactaaa ttcttgtaca
    26941 ataggcttat cattaagatg aaatggagaa aaaagatggc attagaagta acagatgcta
    27001 catttgtaga agaaactaaa gaaggtttag tactcattga tttttgggca acttggtgtg
    27061 gtccatgtcg tatgcaagca ccaatcttag aacagttatc tcaagaaatc gatgaagatg
    27121 aactcaaaat tttgaaaatg gatgttgatg aaaatccgga aactgctcgt cagtttggta
    27181 ttatgtcaat tccaacattg atgtttaaaa aagacggaga agtggttaaa caagttgcag
    27241 gtgttcatac taaagaccaa ctgaaagcta ttattgctga attgagttaa ctaaaataaa
    27301 gcccagcgtc acgctgagct ttattttatg acctactaac ttcaatggaa taaccatgta
    27361 aacataaaac gacttgcaaa agcaaaagca acagtaatga ggaaaaatac agtgacaata
    27421 aggggtttct gataaggaag ttttgctctt tcttctcgtt tttcgatttc gtctaataat
    27481 tttccatttg aaatagctag gatttcctta taaggttgca catcatattt tttcttaaaa
    27541 cgttccacac gattagcata agtcatagta attatcgata ataaaacaaa aatgccaagt
    27601 cctagccact ctaagaaata gacttaatgg ataacttgaa atcattaata gtatcatcaa
    27661 tgttaccatt actttggtat ctcgtttaaa attcttttta tcaacctgag tgatggtata
    27721 tttcattttc tcaatgtctc ctttaatgag ttggtctaag ctcacttgaa aaatttgact
    27781 taggagtaag aggctatgga tgtctgggta agttttgtca ttttcccagt tagatatgct
    27841 ctgacggctt acatagactt tctcggctaa tttttcttgc gagagcgctt gttgtttacg
    27901 gtagcgaata atttgctgac caatttccat aaatatcacc gaaaaacttt acagcggcgt
    27961 aaaggaattg taaacaaaaa gtgaaccgtt atagttcact tgcgattaag catttttctg
    28021 ctttaagtag gtctctagca ttttcttttg cggtgttgca aagggataca gagcaaagtc
    28081 ctcaattgct acccacttta ggtgaggagc attaggtaaa tctgttgctt tgaccacccc
    28141 ctctatgagt tctattgtcc acttctggtg actaaaagtg tgcttaatat ttggaaagtg
    28201 attatcagtc cattggggct ttaattgata ttctctttcg aaagtttcat tttgggtttg
    28261 ccagattatg gggttggatt gattgtcatc aaataaatct aattgttgag aaagaggtga
    28321 cgtttcgata ataggaaatg accaaaaacc tcctagaagt ctccctttag tatttttctc
    28381 cagtagatat tggccatttt ggttacgaat gacaaaagcc tgaattcgca ttggtttagg
    28441 ctttttcttt ggatttttta tggggtattt accataagta ccattcaaat aagcagcgtt
    28501 aaagaaacga atagggcttt catcaggcct aggtgtctta gcggattcga tgtctgtacc
    28561 tagatccata agtgcctggt taaaatcacc gggtctgtca gggtcaatta gtatttccat
    28621 aatagcttga aaaattttac gatttttagg gtcaccgata tcataattaa cttcaaacaa
    28681 acgagccatg acacgcatca cattgccatc aacagcaggc tctggtaagt tgaatgagat
    28741 gctggcgata gcacctgcag tataaggacc aatccctttt aatgaagcaa tatcatcata
    28801 agtgtgagga aatatgccac caaaatcaac catcacttgc tgtgcagcct tttgcatatt
    28861 acgcacccga gaataatagc ctagtccctc ccatgccttt agtaattgtt cttcaggagc
    28921 gtctgccaaa tcttttattt gaggaaacca ctctagaaaa cgtttataat aagggattac
    28981 cgtattaact tgtgtttgtt gcaacatgat ttcagaaacc caaatataat atggattagt
    29041 agttcttcgc caagggagat cacgtttttc ttggtcatac caccctaaaa gtgtgcgacg
    29101 aaaagaagcg attgtctcat tatcccacat attaatacca taatctttta attcaatcat
    29161 gttgttattg taacacagga gccttaaaaa gagtaaaaaa agattttagg tatttgcgaa
    29221 aaagaaaagg aaatattata ataatattag gtttacctca tctaaatgtt gatttagaat
    29281 aactgaaatt aacgatagaa gcagacaggt tttaatttgg aggggacatg ttccagaaat
    29341 taaagaatct tattgatcgg tattcgtggt tcgtttttat aatgatgatt cttgtgttat
    29401 ttcttaacta tatttatcca tttgatcctt ctttgagcgg actacagttg gaatggctga
    29461 tcatgacgca agtttttcct ggattaggta tcgtatgtgc catggttgct attattttta
    29521 aaaagtttaa cctttttgtt ttggccctaa ttttatattt tgcactttgg ttaaaacttt
    29581 tccttgcttt ttcttttttc acctattttt taggagtctg actaagtgcc aatttttaaa
    29641 actcgtgaaa ggaaatgttt gacaaaactt agtcaagtag aaaaagttcc ttgcttttaa
    29701 ttgactatta gtgtacaata agattctgtg agtacacctc acttactcac tccaaaagta
    29761 gtgagtcatt agaccaaaag gaggaaaata tcaatggcta aatacgaaat tctttatatc
    29821 attcgtccaa acattgaaga agaagctaaa aacgctttgg tagcacgctt tgactctatc
    29881 ttgactgaca acggtgcaac tgttgttgaa tcaaaagatt gggaaaaacg tcgtcttgca
    29941 tacgaaatca acgatttccg tgaaggactt taccacatcg ttaaccttga agcgactgac
    30001 gcagcagctc ttaacgagtt tgaccgtctt tcaaaaatca atggtgacat tcttcgtcac
    30061 atgatcgtta aacttgacgc ttaattccaa ctaagagggt agtttatgat taataatgta
    30121 gtactagttg gtcgtatgac caaggatgca gaacttcgtt acacaccaag tcaagtagct
    30181 gtggctacct tcacacttgc tgttaaccgt acctttaaaa gccaaaatgg tgaacgcgag
    30241 gcagatttca ttaactgtgt gatctggcgt caaccggctg aaaatttagc gaactgggct
    30301 aaaaaaggtg ccttgatcgg agttacgggt cgtattcaga cacgtaacta cgaaaaccaa
    30361 caaggacaac gtgtctatgt aacagaagtt gttgcagata atttccaaat gttggaaagt
    30421 cgtgctacac gtgaaggtgg ctcaactggc tcatttaatg gtggttttaa caataacact
    30481 tcatcatcaa acagttactc agcgcctgca caacaaacgc ctaactttgg aagagatgat
    30541 agcccatttg ggaactcaaa cccgatggat atctcagatg acgatcttcc attctagtca
    30601 gaatggattg aacgaatacg aaattatttg agttcgggct aaaaatttag aacttagaat
    30661 ttagatcaac tccctaggaa atcaagattt cttgccagtt ttctaaaatt cagtcgtttt
    30721 ttaagagccc ttaacatcat aatttataaa ggagaaaata catggctcaa caacgtcgtg
    30781 gcggattcaa acgccgtaaa aaagttgact tcatcgcagc taacaaaatt gaatatgttg
    30841 attacaaaga tactgagctt cttagccgtt tcgtttcaga acgtggaaaa attcttcctc
    30901 gtcgtgtaac aggaacttca gctaaaaacc aacgtaaagt aacaacagca atcaaacgtg
    30961 ctcgcgttat ggctcttatg ccttacgtaa acgaagacta ataaacaaac agtccatttc
    31021 ggactgtttt ttagttgact aggactagtc taggcgtata ggtgagtttt ttctaaaaga
    31081 gagaatgata gtaaacgaaa atccttgcgt agacagcaag gatgaaatga ttgttatttg
    31141 ttaacaggtg acatagtgtt ttgaatgttg tatttgcgtt gtaggtaata gcgtaaagca
    31201 agggaaatac caccaataat gagcaaggca agaggaggca actgtgggtt aagagaggtt
    31261 ggtaaaaagg cagtcgcaga gtacaaggca atccaaatca acatggctaa tgataaggct
    31321 gcgatgattt tgaaccaact tggacgaagg ctcttatctt ttccgagatg acggtaaata
    31381 aagtaataag tagcgtacat ggatgctcct ccaccaaaac caagtgccag taaggaaatc
    31441 aatcctgtaa ctgtagcgtt tgtgttgaag aaggtcatga tgccatttaa aagggcaaca
    31501 attccgatga atagcaaaga ggtatctagc cacatcaacc aaggattggt gtttttgtca
    31561 gtttctgctg ctttttgact agggtcttgg ctaaaagaag ctgcccaagc agtcggagtg
    31621 cctaatagat ttcgagcggt gacacctttt ttctggtttt ctagaatagc tggaatggct
    31681 tcttcgagaa tcagcttaat gtcttcatca gacttgccgt cttggattaa tttgttcgta
    31741 gcggtgtgga taaattcttg attttttttg gtaagttctt gtaattccat gggaatccct
    31801 tctttatatg ggttagttaa agtaagtcaa tgatattagc tagtgtcaaa tgagactttg
    31861 gagccagccg tttgacacag agttttgtca ggtgttaact acattctaca gcttgctcca
    31921 ctctagaacc atttttttct aataaagtaa attacaacaa aggaactaag tagcatagca
    31981 atcaaggtaa tataccaaaa agcatgttct aggccattta gtggtaacca gttgttttgg
    32041 aaattcatac cataggcgga gaaaatcaca gttggtatat ctaaagccat ggtcatcaag
    32101 gccagtgttt tcataatagt gttctggttg ttgttgataa tagaagcagt ggtttcagtc
    32161 atggcattca agacattttc ataaatgcca gccatctcaa tggcctgttg ggtttcaatc
    32221 aaggtatctt ctagcaaatc ctcgtcctca atgtatttct tgagagagct tgttgagctg
    32281 gataatttct tgacgatgcg ttcgttgaat ttcaaggaag cctttaagta gacaatggat
    32341 ttttcaagtt ccatcatgtc gataagttct tcatttcgag tagctgcttc aagctgagct
    32401 tccaaacgtt cgctttggcg atcaatggtc ctcaaggcag tcagaaagag ctcggcgttg
    32461 cgatatagaa tctgaaaaac aaaacgtgtc ttcatgaagg tatagaaatt tttgacccgg
    32521 cggttgtgaa aatgatcgaa aagggtcatg tcatgcagac aagttgtgat aacagcattt
    32581 tccgttacaa taatgcctaa aggcatagta atatagtaac ttttattgtt acgttcttcg
    32641 tatatcggga cgtctacgat aattagggta taatcatctt ctacggcaat acgtgaggtt
    32701 tcttccacgt ccaaaggggc gcgcaagtca gaaatatcaa tgttaaattg atcggcgatc
    32761 ttcatagact cttcttggga agggttaacc agtttaatcc aagctcctgg ctcgaatgtt
    32821 tctatttctt tgaattcaat tgccgatgaa agaaacattt gtttcatgac aagccctcct
    32881 ttttgatgat tgactggtag agattgacat caaaccttga taataaagcc ttctcaagga
    32941 ttttctgaaa aattctcaat acttatctat tataccaaaa ttcgcaaagt ttggggcaat
    33001 aggttatcag aaatttttgt tataatataa gaaagctcga tgaggagggt gcctttaggc
    33061 acattcaaga tgcaaaataa aataataatt catggggcaa gagcccacaa tttaaaaaat
    33121 attgacgtgg aaattccacg agacaaatta gttgtcgtga cagggttatc agggtcagga
    33181 aaatctagtc tagcctttga tactatttat gcggaagggc aacgtcgtta cgtagaaagt
    33241 ttatcagctt atgctagaca gttcttgggt aatatggaaa aaccagatgt ggattccatt
    33301 gacggtctta gccctgctat ttccattgat caaaaaacta ccagtaagaa cccccgctca
    33361 acggttggta cggttacgga aatcaatgat tatttacgtt tactatatgc gcgtgtgggc
    33421 acaccttact gtattaatgg gcatggggcc attacagcat cttctgcaga acaaattgta
    33481 gagcaggtct tagccctccc tgaacggaca cgcatgcaga ttttagcgcc tattgttcgc
    33541 cggaaaaaag gtcaacacaa aaccattttt gagaaaattc aaaaagatgg ttatgtccgt
    33601 gtgcgggttg acggggatat ttttgacgtg acagaagtgc cggagctgtc caaaagtaag
    33661 atgcacaaca tcgaggtggt tattgaccgt ctggttaata aggatggtat tcgtagccgt
    33721 ttatttgatt cggttgaagc agctttaagg ctgggagatg gctaccttat gattgacact
    33781 atggatggca atgaactgct cttttctgag cattattcct gtcctgtctg tgggtttacg
    33841 gttcctgaat tagaaccaag actcttctct tttaatgcgc cgttcggctc ttgtccgacc
    33901 tgtgatgggc taggcattaa gttggaagtg gatttggact tggttgttcc tgacccaagt
    33961 aagtctttga gagagggagc tttggcgcct tggaatccta tttcctccaa ttattaccca
    34021 accatgcttg agcaagctat ggcaagtttt ggggtggata tggatacacc ttttgaggcc
    34081 ttgactgagg aagaaagaga tttagtgctt tatggttcag gagatagaga atttcatttt
    34141 cactatgtga atgattttgg tggtgagcgt aacattgata ttccttttga aggtgttgtg
    34201 actaatgtta atcgtcgtta tcacgaaact aatagtgatt atacgcgcaa tgtgatgcgt
    34261 ggttatatga acgaattgac ctgtgcgact tgtcatggtt accgtttgaa tgaccaagcc
    34321 ttgtgtgtgc atgtgggtgg cgaagaagga cctcatattg gtcaaatttc agaattatcg
    34381 attgccgacc acttgcagtt gttggaagaa ttggaactca cagaaaatga aagtaccatt
    34441 gctaaaccga ttgtcaaaga aattcatgac cgcctgacct tcttaaataa tgtgggactg
    34501 aattatctga ccttgtcacg ggctgctggg actttatcag gtggtgaaag tcaacgaatc
    34561 aggttagcga cacaaattgg ttctaactta tcaggggtga tctatatctt ggatgagcct
    34621 tctattggat tgcaccaaag agacaatgac cgtttgatcg aaagcctgaa aaaaatgcgt
    34681 gatttgggta ataccttaat tgtggtagaa cacgatgaag acaccatgat gcaggcagac
    34741 tggctgattg atgtggggcc tggggcaggt gagttcggtg gagaaattat tgcctctgga
    34801 acgccgaaac aagtggctaa gaataaaaaa tccatcacgg gtcaatattt gtctggtaaa
    34861 aaattcattc cagtgccatt agagcgtcgt tctggtaatg ggcgattcat tgaaataaaa
    34921 ggagcagcgc agaataatct tcaaagcctc gacgtgagat tcccactggg taaatttatt
    34981 gcggtcacag gggtatcagg ctcagggaaa tcaaccttgg ttaatagtat tttgaaaaag
    35041 gctgtcgccc aaaaattaaa ccgtaatgct gataagcctg gtaaatatca ctctatttct
    35101 ggtattgaac atattgaacg cttgattgac attgaccaaa gtccgattgg aaggacgcca
    35161 cggtcaaatc cagccaccta tacgggtgtc tttgatgata ttcgagactt gtttgcccaa
    35221 accaacgaag ctaagattcg tggctacaaa aaaggccgtt tctcttttaa tgtcaaaggt
    35281 gggcgttgtg aggcttgttc aggtgatggg attatcaaaa tcgaaatgca ctttttgcca
    35341 gatgtttatg tgccttgtga ggtttgccac ggcagacggt ataattctga gacgcttgag
    35401 gtgcattata aagaaaaaaa tattgctgaa gtacttgaca tgactgtcga tgatgccttg
    35461 gtatttttct ctgctatccc taaaattgcc cgaaaaattc aaaccattaa ggatgttggt
    35521 ttgggttatg tgaccttggg tcaaccagct actactctat ctggaggaga agcgcagcgg
    35581 atgaaattag ctagtgaatt gcacaaacgc tcgacaggta agagcttgta tatcctagat
    35641 gagccaacga ctggtttaca cacagatgat attgcaaggc tattaaaagt tttggaacgc
    35701 tttgtagacg atggtaatac ggttcttgtg attgagcata atttggacgt tatcaaatct
    35761 gctgaccata ttattgactt aggaccagaa ggtggtgtcg gaggtggtca gattgttgcc
    35821 acggggacac cagaagaggt agctcaagtt aaagaaagct atactggtca ttatttgaaa
    35881 gtaaaactac aacaatagga ttaggagttc gtttgagctc ctttttaatc ttttaaatgc
    35941 tctcaaatca tggtaaactt aaagtagttt tttcatgcta caatattctc aaaagttacc
    36001 aaaggagttc gcgatgtcag gatttttaga gcaacgatta ggtcactgcc taaggcagat
    36061 ggcagagaag gggctagagg ctcttctagt cacccattta accaatagtt attacttgac
    36121 aggtttttct ggaactgcag caactgtttt gataacggcc aaacgtcgtg ttttgatcac
    36181 agattcacgt tataccttgc ttgctaaagc tagtgttgag ggatttgata ttatcgaaag
    36241 ccgcacgccg cttaaggttg tggcagaatt gttagaggct gatcaaatag attgccttgg
    36301 ttttgaggac caggtatcgt tttcttttta tcaggccatg caagcagaac tgtcaggaat
    36361 aaccttgctt gctcagtcag gttttgtgga gcatttacgt tttattaagg atacttctga
    36421 aattgatacc attgctaaag cgtgctcgat ctcagacaaa gcatttgaag atgctcttga
    36481 ttttattaaa ccagggacaa ccactgaacg tgacctggct aattttttag attttcgtat
    36541 gcgtcagtat ggtgccagcg gcacatcatt tgatatcatt gtagcttcag gctatcgctc
    36601 tgccatgcct catggacgcg ccagtgacaa ggttatccag aataaagaga gcttgaccat
    36661 ggactttggg tgttactaca atcactatgt tagtgatatg acgaggacca ttcatattgg
    36721 ccaagttact gatgaagaac gtgagattta tgctcttgtt cttgctgcta ataaggctct
    36781 cattgataaa gctagcgctg gtatgactta tagcgatttt gacggtattc cgcgccaact
    36841 catcactgag gctggttatg gtagtcactt cacacatggc attggtcatg gtatcgggct
    36901 tgacatccat gagaatccgt tttttggtaa atctgagcaa cttcttcaag caggaatggt
    36961 ggtaacagac gagccaggaa tctatctgga taataaatat ggcgtccgta ttgaagatga
    37021 cttggtcatc acagaaactg gctgtcaagt attgaccttg gcaccaaagg aactgattgt
    37081 gttgtaaatt atcttaggga aggattagaa ggacgaagca atgacaaatc gtttatcatg
    37141 gcaagattac tttatggcca atgcagagct tatttccaaa cgctctacct gtgaccgcgc
    37201 ctttgtggga gctgttttgg taaaggataa tcgtattatt gccacgggtt ataatggtgg
    37261 tgtttctgcc acagataatt gtaatgaagc gggccattat atggaagatg gacattgcat
    37321 caggacagtt catgctgaaa tgaatgcttt gattcaatgt gcgaaagaag ggatttcgac
    37381 tgacggaact gaaatttatg taacgcactt tccctgtatc aactgtacca aggctctgtt
    37441 gcaggctggg attaaaaaga ttacttacaa agcacattat cgtccgcacc cgtttgcgat
    37501 tgaactaatg gagaaaaagg gagttgcgta cgttcaacac gacgtgcctc acatcatttt
    37561 gggtggtaag gaaggaccta atggttagct tgggcgaatg gtcataaaag atttgagcct
    37621 agggcgcttt tgtggtaaaa tgaagtgata atattttagt aagaggtaaa taataatgat
    37681 tgaagcaagt aagcttaaag ccggtatgac attcgaatca gaagggaaat taattcgtgt
    37741 ccttgaagct agccaccata aaccaggtaa aggaaacaca attatgcgta tgaaattgcg
    37801 tgatgtgcgt acagggtcta cctttgacac aacttaccgt ccagatgaaa aatttgagca
    37861 agctatcatt gaaactgttc cagcacaata cctatataaa atggatgaca ctgcttactt
    37921 catgaatact gacacttacg atcagtacga aattccagtt gctaacgttg agcaagagtt
    37981 gctttacatt cttgaaaact cagacgttaa aatccaattc tatggaagcg aagtgattgg
    38041 agtgactgtt ccaacaaccg ttgaattgac tgttgccgaa acacaaccat ctatcaaagg
    38101 tgcaactgtc acaggttctg gtaaacctgc aactcttgaa acaggtcttg tggtcaacgt
    38161 tccagacttt atcgaagctg gtcaaaaact aatcatcaac actgcagaag gtacttacgt
    38221 ttctcgtgct taatcctttg tcagaacagg ttagtctaaa gaagagaaag gaaatgctat
    38281 gacaactgaa catatcggtg aaatcgttat ttcaccacga gtacttgagg ttattactgg
    38341 gattgctacc acacaagttg agggcgttca ttcccttcat aacaaaaaaa tggcagatag
    38401 ctttaacaaa gcaagtcttg gtaaaggggt ttatctccag acagaagaag atggaagtgt
    38461 tacagcagat atttatgttt acttgcaata tggagttaag gtcccgactg tatctatgaa
    38521 tattcaaaaa acagtcaaat ctgctgtgta cgatatggca gaagtgccta tttctgcagt
    38581 taatatccat gttgaaggta ttgttgcgga aaagacacca aaaccagatt tgaagtcact
    38641 ttttgatgag gatttcttgg atgactaaca gctttcaaaa ttcaagaaga gatttgcgtg
    38701 aacgtgcctt tcaggcttta tttaacatag agatgggagc tgagttattg gcagcttctc
    38761 agtttgccta tggttatgat aaagtaacag gggaggacgc tcaagtattg gagctgccga
    38821 tttttttatt aagtcttgtg acgggtgtca ataatcataa agaagagttg gataacttga
    38881 tatcaactca tttgaaaaaa ggttggtcgt tagaacgctt gacactaaca gacaaaacgt
    38941 tattacgact aggtcttttt gaaatcaagt attttgacga aacaccagac cgtgttgcac
    39001 taaacgaaat cattgaagta gctaaaaaat attctgatga aacctctgct aaatttatta
    39061 atggcttact tagccaatat gtctcggaag ctccttcagc aaataaatca taataagtcg
    39121 gagcaatctt aggattgtat ccgatttttt caatttatgt acgaatatta aaagacaaac
    39181 aagcatactc tcgcatctag aaagagtatg cttgtttgtc ttttagagta attagtgatt
    39241 ggttatgttt tgtttaaata cttgctcctg gaagtagcgt aatcggtaaa atatagtctt
    39301 tacttgtttt ttctttttta atttttttga tgagtatttc gacactcaat ttagcaatct
    39361 catcaatagg ttgacgaatg gtcgctaatt gaggaacata ttgctggata aatgtcgttc
    39421 catcataacc tatgactttc atatcctctg gaatagtaat gtgaagttgt ttggctactt
    39481 tcataatgag gatagcagtt aaatcatcag aaacgaaaag gccatcaggt tttcgggttg
    39541 ccaaaatgga tttaatttcc atttcgcgtc taacaggaga taggttattt ggtaatttga
    39601 tgatttctgc acttcgtttg agctggtagt taaaccctag ctggcgcaac cctgtgggcg
    39661 aatcagaatt gtcattacct gtaatcatga caatgttttg acaaccgtgt ttttgcaaag
    39721 tttgtgcggc taatttacca ccttcaaaat tatctgaaga aataaccgga atatttggcg
    39781 ccagattacg gtcaaaagct acaataggag cttcgacacg ctcataatcc tcaattccca
    39841 aattatgact ggaagaaata atgccgtcca cttgattggc cgcaagcatt tctaagtatt
    39901 cgcgttcttt gacgggatta tgttcactat tgcaaataat agttttgtag ccctgtttaa
    39961 acaattcaat ttccaaatgt tcaattaatt cagcgtaaaa gatattgcta atgttgggga
    40021 agataagccc aatgagttgg gttgatttac cttgcaaact tctagcgaga ttgttaggct
    40081 tgtagcccaa ttcacgcatg gccttattca ccttattcac tgttttttgg gaaaggtagc
    40141 ctttttggtt gattactcgc gaaacagttg ttggactgac acccgccaag gctgccacgt
    40201 ctgttaattt tgcgaccact tgcctaatac ctcatttcat aataatgtcc aaaagcttgt
    40261 ccttctacta cttggatacc tgtttgtcct tgggttggga aaacacgact agttaggact
    40321 ttttgccctt ggttaataaa gatttcaaga atggaattgt ccacatagac attaagtgta
    40381 acatggcctt gtgggatttg gcaagagcgc accgtaccat agtcttgggc atattgaacc
    40441 cctgcccgac ttcggtcaat gcttaactgt ccttttgttg tatccacctt caatcttagg
    40501 ccattccctt tttggtcggc aaataggagc aggtcaagct ttttttggcc tggaatcgtc
    40561 aattccaatt cataacagtt agaactgtct attttattat gaaataattc tgctggccct
    40621 cgaagatttt gtagggctga aacaggtgtt tgatagagaa ttccgtcttt aatccttaat
    40681 tctttcacta aactaagagc tccttgatag tcataacgat ctgtcggata atcaatatct
    40741 ggtaacccaa tccaagacac ggctagaacc ctgccatctg gactactaaa ggcttgagtg
    40801 gcataagctt caaaaccaaa gtcaagattt tgaagggccc ccccacccag caattggcca
    40861 gtttctggat tgaagctttc aaaaatttta taggtattgg ggtagatatt ttgataatct
    40921 aaatcagctt tagccagtcc ttgtgggctg aaaatcaaaa caggcttgtc atcgacaaac
    40981 acaaggttgg ggcattcaat catgtattcc gtgccagaat cgtcaaagtc caaatcggct
    41041 ataaatcgcc agttgtccac atgattgtcc acagctttgt aaagtttgat ttttcctttg
    41101 ccatctaaac cttgggcgcc aataatagca tagaattgac cttgataaga aaaaagctga
    41161 ggatcccgaa aatgttctgt aacatcatcg ggctgttcaa tcaaaacctg tggtattttg
    41221 gaaatatttc cttgtttatc catccatgcg ccaacctgta atggtgttct gacccaattg
    41281 gcatcgcgaa cattaccagt gtaaaagagg aagagcttgt catcaatagc ataggcagaa
    41341 cctgagtaag ccccatgact atcgtgagcg tggtctggca gaaggcggct ccttgtttcc
    41401 gtaaaatgga cgaggtctgt ggatgtcatg tgtacccatt gtttcagacc atgcgcagcc
    41461 ccataaggcc agttttgata aaaaagatgg tagtgaccgt tgaaataaga aaacccattg
    41521 gggtcattga gtaatcctgt cttaggttcg acatgaaatt ggctgtgcca tggggattgg
    41581 gccatttttt cagtaatagc ttggtagtct tttgagctcc actctttgta agggcggtag
    41641 cgaatagctt gtggtagatc catcaaaatc tccttgtttt atagtcgtct tcaagaatat
    41701 actaaacgtt ttctgtttaa aaatcaagaa tttaaagcat ataaaataaa aatatgttaa
    41761 acgcttgaca taaaaaatat tagtgataaa atgatagtca agaagtgaag cggattcact
    41821 agcgttggtc atgcacattc ttagccacaa agctggcaga atggatgagg gactaacacc
    41881 aaatgaaaaa ggagactttt aggcatggat aatcgtcaga ttgcaactga agtgattgag
    41941 gctttaggtg gccgagaaaa tgtgagaagt gttgcccact gtgcaactcg ccttcgcgtg
    42001 atggttcatg atgaaggaaa gattgataag gaaaaagcag aagctattga caaggttaaa
    42061 ggagctttct ttaattctgg tcaatatcaa atgatttttg gaactggtac cgtcaataac
    42121 atttatgacg aagtcgttgc tcttggttta ccaacatcat caaccagtga gcaaaaggca
    42181 gaagcaggca aacaaggcaa tatcttccaa cgggcgattc gtacgtttgg agatgttttt
    42241 gttcccatta ttccagctat tgtagcaacg ggtctcttta tgggggttcg tggtttggtg
    42301 acccagccag ctattatgga tttatttggg gtgcatgagt acggggaaaa ttttctcatg
    42361 tacactcgta ttctaacgga tacagccttt gtctacttgc cagctttggt ggcttggtca
    42421 gcctttaggg tctttggggg taatcctatt atcggtattg ttttaggttt gatgctggtg
    42481 tccaatgaat tgcctaatgc ttgggtagtt gcctctggtg gagatgttaa gccgctaacc
    42541 ttctttggat ttgttcctgt tgttggttat caaggtaccg ttttacctgc cttctttgtt
    42601 ggtctggtag gagctaagtt ggagaaatgg ttgcacaaaa aggttccaga agctttagac
    42661 ttattggtca caccgttttt aacgtttgct attatgagta ccttgggact atttgtgatt
    42721 ggaccagttt tccattctct tgaaaacctt gttctggctg ggacacaggc cgtcttgcat
    42781 ttgccgtttg gcattgctgg tcttattgtt ggtggtatcc aacagttgat cgtcgttact
    42841 ggtattcacc atatctttaa cttcctagaa gcgcagctaa ttgccaatac cggaaaagat
    42901 cctttcaatg cttacctaac agcagcaaca gctgctcaag ctggagctac cttagctgtt
    42961 gctgttaaaa ccaaatcaac aaaactaaaa ggtctggcct ttccatcaac cttgtcagct
    43021 cttttaggga ttactgaacc agctattttt ggggtcaacc tccgttatcc aaaagtcttt
    43081 gtttcaggtc ttattggtgg tgccttaggt ggttgggtcg ctgggctctt tggcattgca
    43141 ggaactggtt ttgggattac ggtcttacca ggaactctcc tttacttgaa tggccattta
    43201 ttacaatacc ttgtgactat gcttgtcggt cttggggtag cctttggaat tgcttatact
    43261 tggggttatc aagatagaga aacccttccg ttaccagctg tcgaagttga tcaaacggct
    43321 gatcagccag ccttagcaga ggaaacttta tatagtcctt tgaatggaac agttgtagat
    43381 ttagcagctg tttcagaccc tgttttttca tcaggtgcta tgggtcaagg cttagcaatt
    43441 aagccagaag ataataccct atactcacca gttgatggta aagttgaaat tgtctttgaa
    43501 acaggtcatg cctatgctat aacgtcaagt caaggagcag aagtgttact tcatattggt
    43561 attgacactg tgtcgatggc aggagatggc tttgaatctc ttgtagcagt aggtcaggcg
    43621 gttaaaaaag gtgatcttct tggacacttt gatcctagca agattgcaga agctggacta
    43681 gatgacacca ccatgatgat tgtgaccaat agcgctgact atcaaagcgt ggacattctt
    43741 gctcaaggac atgttttgat tggtgatcaa gtggcactta tcaaataagg acaaaagagc
    43801 taactaagca gctcttttgt cctgccattc atggcaggtt ggcaaaaaaa tgagaaaagc
    43861 ctaaaaacct taaatttgtg ttattttacc tatactttgt accttgtttt ttttaataaa
    43921 gtgttgttat acttaaggcg aactatagga atgcgcttac atagatggta tatcaactgg
    43981 gaagccatga cttagtacca aaaataagga gtgtccaaat ggataaacat ttgttggtaa
    44041 aaagaacact agggtgtgtt tgtgctgcaa cgttgatggg agctgcctta gcgacccacc
    44101 atgattcact caatactgta aaagcggagg agaagactgt tcaggttcag aaagaattat
    44161 cttctataga tagcttgcat tatctgtcag agaatagcaa aaaagaattt aaagaagaac
    44221 tctcaaaagc ggggcaagaa tctcaaaagg tcaaagagat attagcaaaa gctcagcagg
    44281 cagataaaca agctcaagaa cttgccaaaa tgaaaattcc tgagaaaata ccgatgaaac
    44341 cgttacatgg tcctctctac ggtggttact ttagaacttg gcatgacaaa acatcagatc
    44401 caacagaaaa agacaaagtt aactcgatgg gagagcttcc taaagaagta gatctagcct
    44461 ttattttcca cgattggaca aaagattata gccttttttg gaaagaattg gccaccaaac
    44521 atgtgccaaa gttaaacaag caagggacac gtgtcattcg taccattcca tggcgtttcc
    44581 tagctggagg tgataacagt ggtattgcag aagataccag taaataccca aatacaccag
    44641 agggaaataa agctttagcc aaagctattg ttgatgaata tgtttataaa tacaaccttg
    44701 atggcttaga tgtggatgtt gaacatgata gtatcccgaa agtaaatgga gaagctagtg
    44761 acgaaaatct caagcgatct attgatgttt ttgaagagat tgggaaatta attggaccaa
    44821 aaggtgctga taaatcgcgt ctgtttatta tggatagcac ctacatggct gataaaaacc
    44881 cattgattga gcgaggagct ccttatattg atttgttatt ggtacaagtc tatggcgcaa
    44941 gaggagaaca aggtgagttt caaaacgata ccaagttagt tacagatacc cctgaagaac
    45001 gatggcaagg ttatagcaag tatattcgtc ctgaacaata catgattggt ttttctttct
    45061 atgaggaaag agcaggcagc ggcaatcttt ggtatgatat taattctcgc aaggacgagg
    45121 acaaagcaaa tggaattaac actgacataa ctggaacgcg tgccgaacgg tatgcaaggt
    45181 ggcaacctaa aacaggtggg gttaagggag gaatcttctc ctatgctgtg gatcgtgatg
    45241 gtgtagctca tcaacccaaa caaatagctg aaaaagataa acagaatgta aaaaataatc
    45301 aacctcagat tccagagatt actgataaca ttttccactc agattatagt gtctccaagg
    45361 cactaaagac agttatgcta aaagataagt cgtatgatct gattgatgag aaagatttcc
    45421 cagataaggc tttgcgagaa gctgtgatgg cgcaggttgg aaccagaaaa ggtgatttgg
    45481 aacgtttcaa tggcatatta cgattggata atccagcgat tcaaagttta gaaggtctaa
    45541 ataaatttaa aaaattagct caattagact tgattggctt atctcgcatt acaaagctcg
    45601 accaatctgt tttacccgct aatatgaagc caggcaaaga taccttggaa acagttcttg
    45661 aaacctataa aaaggataac aaagaagaac ctgctactat cccaccagta tctttgaagg
    45721 tttctggttt aactggtctg aaagaattag atttgtcagg ttttgaccgt gaaaccttgg
    45781 ctggtcttga tgtcgctact ctaacgtctt tagaaaaagt tgatatttct ggcaacaaac
    45841 ttgatttggc tccaggaaca gaaaatcgac aaatttttga tactatgcta tcaactgtca
    45901 gcaatcatgt tggaagcaat gaacaaacag tgaaatttga caagcaaaaa ccaactgggc
    45961 attacccaga tacctatggc aaaactagtc tgcgcttacc agtggcaaat ggaaaagttg
    46021 atttgcaaag ccagcttttg tttgggactg tgacgaatca aggaacccta atcaatagcg
    46081 aagcagacta taaggcttac caaaatcagc agattgctgg acgtagcttt gttgattcaa
    46141 actatcatta caataacttt aaagtttctt atgagaacta taccgttaaa gtaactgatt
    46201 ccacattggg aaccactact gacaaaacgc tagcgactga taaagaagag acctataagg
    46261 ttgacttctt tagcccagca gataagacaa aagctgttca tactgctaaa gtgattgttg
    46321 gtgacgaaaa aaccatgatg gttaatttgg cagaaggcgc aacagttatt ggaggaagcg
    46381 ctgatcctgt aaatgcaaga aaggtatttg atgggcaact gggcagtgag actgataata
    46441 tctctttagg atgggattct aagcaaagta ttatatttaa attgaaagaa gatggattaa
    46501 taaagtattg gcgtttcttc aatgattcag cccgaaatcc taagacaacc aataaaccta
    46561 ttcaggaagc aagtctgcaa atttttaata tcaaagatta taatctagat aatttgttgg
    46621 aaaatcccaa taaatttgat gatgaaaaat attggattac tgtagatact tacagtgcac
    46681 aaggagagag agctactgca ttcagtaata cattaaataa tattactagt aaatattggc
    46741 gagttgtctt tgatactaaa ggagatagat atagttcgcc agtagtccct gaactccaaa
    46801 ttttaggtta tccgttacct aacgccgaca ctatcatgaa aacagtaact attgctaaag
    46861 gtctatctca acaaaaagat aagttttctc aaaagatgct tgatgagtta aaaataaaag
    46921 agatggcttt agaaacttct ttgaacagta agatttttga tgtaactgct attaatgcta
    46981 atgctggagt tttgaaagat tgtattgaaa aaaggcagct gctaaaaaaa taaacaaagc
    47041 aactttctta gatagcaaca ttcagattaa attaacaaaa tgtgactatg ataaaggttt
    47101 gctggaattg attaaccaaa agactaaaaa tctgagatga atagtcccag atttttagtc
    47161 ttttataggt tttgatgaca taaagctaaa taatcgttag actaccagaa agtggcactt
    47221 gtccgtgaga catggctgtc ttgataagag cctgtgtcat cataaagata aaaaagaaca
    47281 agaaaaagga gaaaacatgg gaaaattata tggaagcatt gaagctggtg ggacaaagtt
    47341 tgtctgtgcc gtgggtgatg aggagtttac agtggtggat aaaacacaat ttctgaccac
    47401 cacaccagaa gaaaccatcg cgcgaaccat cgcttatttt aaagcttttg aggcagattt
    47461 ggctggaatg gcgattggtt cttttggacc aattgatatt gatccgtcgt cagagactta
    47521 cggtcatatc acaaccactc ctaagtcagg ctgggctaat gtggatttgt taggacaact
    47581 ttcggctgct tttaagattc cttttgatgt gacaacagat gttaatagct ctgcttatgg
    47641 tgaggtgctt gctcgtcctg gtgtggaaag tttggtctat tacaccatag gtactggtat
    47701 tggggcggga gctattcaac atggccactt tattggggga ttaggtcata cagaagcggg
    47761 tcatacctat gtcatgcccc atcctgatga tatggccaag ggatttttag gtgtttgccc
    47821 ttttcataaa gggtgtctgg aagggatggc agcaggtcca agtattgagg ccagaacggg
    47881 agtgagaggt gaacggcttg atcaggaagc tgatgtttgg gacattcaag ccttctacat
    47941 tgcccaagca gcgctgcaag caactatgct ttaccgtcct caagtgattg tttttggcgg
    48001 aggtgtcatg acgcaagaac atatggtgtt gcgcgtgcat gataaattca ctaccctttt
    48061 aagcggttat ttgccagtcc ctgatttgac agactacatt gttactccag ctgttgctga
    48121 taatggctcc gctactctgg gaaattttgc tttggccaag ttggctgcac aaggaaaata
    48181 gggtctgttt ttgcctgctt gtctagtaaa agaaagcgca gtcagctaga acatgctata
    48241 ataaacagag attaacatca gaagcgagga atattatgtc agaaccatta tttctaaaat
    48301 caaccatgca cgacagaatt tggggtggca ccaagttgag agatgtcttt gcttacaaca
    48361 tcccaagtga caccacaggt gagtattggg ctatttctgc tcatcctaat ggtgtttcga
    48421 cagttactaa tggacgttat caaggacaac ctttaaatac attatatgcg caagagccgg
    48481 ccttgtttgg gaatccaaag gaagaagttt ttccactgtt aactaagatt ttagatgcta
    48541 atgactggct aagtgtccaa gttcatcctg atgatgctta tggacgtgaa catgaaggag
    48601 aattaggcaa gacagaatgc tggtatatta tttctgccga agaaggttct gaaattgtat
    48661 acggccatca ggccaagtcc aaagaagacc ttcgtgccat gattgaagca ggcgcttggg
    48721 atgatttgct gactcgtgtc ccagtcaaag caggcgattt tttctatgtt ccaagtggca
    48781 ccatgcatgc gatcggcaag ggaattctta ttttagaaac ccagcagtca tctgatacca
    48841 cttatcgggt ttatgatttt gaccgtaagg acgttaatgg taatcttcgt gaccttcata
    48901 ttgaaaagtc tattgatgtc ttaacgattg gtaagccaga aaatagcgtg ccagccacta
    48961 tagttttgga taatatggta gaaacaactt tagtctcaac gccatttttc actgtttaca
    49021 aatgggtaac tagtcaaatg gttgacatga aacaagctgc gccttatctt ttagtgagtg
    49081 ttttaaaagg tcaaggaaaa ctctatgtgg accagaaggc ttatgagcta gaaaaaggca
    49141 tgcactttat cttgcctaac gatgttaaat cgtggtcatt tgatggtcaa ttagaaatga
    49201 ttgtgagtca ccccaatcaa ctcgtttaat accatggtat caatgtgaga aaaaaggata
    49261 aaattatgac tctctgtttc tctgataact tta
//
LOCUS       DATWVB010000012        46406 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.012, whole genome shotgun sequence.
ACCESSION   DATWVB010000012 DATWVB010000000
VERSION     DATWVB010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46406
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.012"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            144..1376
                     /locus_tag="VCX65_000737"
     CDS             144..1376
                     /locus_tag="VCX65_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEP5053211.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDTKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFDGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLSVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            1544..2725
                     /locus_tag="VCX65_000738"
     CDS             1544..2725
                     /locus_tag="VCX65_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEP5053212.1"
                     /translation="MTKRIILTIFTFICFSVMPLVQAEDVMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRINA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSPKQQHFKATKKQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(2877..4295)
                     /gene="sufB"
                     /locus_tag="VCX65_000739"
     CDS             complement(2877..4295)
                     /gene="sufB"
                     /locus_tag="VCX65_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEP5053213.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(4288..4767)
                     /locus_tag="VCX65_000740"
     CDS             complement(4288..4767)
                     /locus_tag="VCX65_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEP5053214.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            complement(4754..5980)
                     /locus_tag="VCX65_000741"
     CDS             complement(4754..5980)
                     /locus_tag="VCX65_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP5053215.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATHKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMIDFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(6011..7273)
                     /gene="sufD"
                     /locus_tag="VCX65_000742"
     CDS             complement(6011..7273)
                     /gene="sufD"
                     /locus_tag="VCX65_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEP5053216.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLAALEAIPELELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKTSANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKGAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVIAEIPIPSVHQEIIKVLDEKLLNR"
     gene            complement(7368..8138)
                     /gene="sufC"
                     /locus_tag="VCX65_000743"
     CDS             complement(7368..8138)
                     /gene="sufC"
                     /locus_tag="VCX65_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEP5053217.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADKDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(8260..9429)
                     /locus_tag="VCX65_000744"
     CDS             complement(8260..9429)
                     /locus_tag="VCX65_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEP5053218.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLISAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(9436..10197)
                     /gene="mecA"
                     /locus_tag="VCX65_000745"
     CDS             complement(9436..10197)
                     /gene="mecA"
                     /locus_tag="VCX65_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEP5053219.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(10343..11182)
                     /locus_tag="VCX65_000746"
     CDS             complement(10343..11182)
                     /locus_tag="VCX65_000746"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEP5053220.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(11248..13173)
                     /locus_tag="VCX65_000747"
     CDS             complement(11248..13173)
                     /locus_tag="VCX65_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEP5053221.1"
                     /translation="MKKILMTLVLCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRAGHLPAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVIWQLHHLLTAYQDVAELNWTPISDWDKTLEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGEEPV
                     DVSTSKKNKIVALETKISRRRALLQLLFGKVIPLVEVGFLLWQLIQFIRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLTQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKVTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASAAITNNVLETIKKLNLPDTYRQM
                     TPAEKRKSNSVQGLGCLLLVLNSGLLIYLAIKESGLALIYLALMVLTMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYAK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFLSSLSSATTSSNFSVSSGGGIS
                     GGGGFSGGGGGGGGGAF"
     gene            13371..14939
                     /locus_tag="VCX65_000748"
     CDS             13371..14939
                     /locus_tag="VCX65_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEP5053222.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKAS
                     FLGQMWAILKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRHIERRFDADTYT
                     TGANQMQIAEVSNV"
     gene            14932..15672
                     /locus_tag="VCX65_000749"
     CDS             14932..15672
                     /locus_tag="VCX65_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP5053223.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDHIIFMDKGL
                     ITEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            15814..15930
                     /locus_tag="VCX65_000750"
     CDS             15814..15930
                     /locus_tag="VCX65_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEP5053224.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(16156..17166)
                     /gene="gap"
                     /locus_tag="VCX65_000751"
     CDS             complement(16156..17166)
                     /gene="gap"
                     /locus_tag="VCX65_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEP5053225.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(17514..19592)
                     /gene="fusA"
                     /locus_tag="VCX65_000752"
     CDS             complement(17514..19592)
                     /gene="fusA"
                     /locus_tag="VCX65_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEP5053226.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(19959..20429)
                     /gene="rpsG"
                     /locus_tag="VCX65_000753"
     CDS             complement(19959..20429)
                     /gene="rpsG"
                     /locus_tag="VCX65_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEP5053227.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFSAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            complement(20450..20863)
                     /gene="rpsL"
                     /locus_tag="VCX65_000754"
     CDS             complement(20450..20863)
                     /gene="rpsL"
                     /locus_tag="VCX65_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEP5053228.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            complement(21071..23692)
                     /locus_tag="VCX65_000755"
     CDS             complement(21071..23692)
                     /locus_tag="VCX65_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEP5053229.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASGET
                     KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINHLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKV
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKRNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEVLAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQETLAALQAKQSSLEATIATTEHQLTLLKTLANEKGYRHLDED
                     IATVPDLQVAPPLTGVKPLSYSKIDTTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESK"
     gene            complement(23683..24522)
                     /gene="purR"
                     /locus_tag="VCX65_000756"
     CDS             complement(23683..24522)
                     /gene="purR"
                     /locus_tag="VCX65_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEP5053230.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            complement(24789..25727)
                     /locus_tag="VCX65_000757"
     CDS             complement(24789..25727)
                     /locus_tag="VCX65_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEP5053231.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVTEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            complement(25717..26988)
                     /locus_tag="VCX65_000758"
     CDS             complement(25717..26988)
                     /locus_tag="VCX65_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEP5053232.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     ITYQLDTANKQQLLELTQLMNRQQADLYQQLTDIRDVLHRSLSDSRDRSDKRLEEINQ
                     QVNQSLKNMQESNEKRLEEMRQIVEEKLEETLKNRLHASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNAAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQTTKSLLNMPLLEEENNEN"
     gene            complement(26990..27622)
                     /locus_tag="VCX65_000759"
     CDS             complement(26990..27622)
                     /locus_tag="VCX65_000759"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEP5053233.1"
                     /translation="MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVSQKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            complement(27615..28277)
                     /locus_tag="VCX65_000760"
     CDS             complement(27615..28277)
                     /locus_tag="VCX65_000760"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEP5053234.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGVDIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            complement(28287..29159)
                     /gene="rsgA"
                     /locus_tag="VCX65_000761"
     CDS             complement(28287..29159)
                     /gene="rsgA"
                     /locus_tag="VCX65_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEP5053235.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            complement(29583..30455)
                     /gene="rsmA"
                     /locus_tag="VCX65_000762"
     CDS             complement(29583..30455)
                     /gene="rsmA"
                     /locus_tag="VCX65_000762"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEP5053236.1"
                     /translation="MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVKD
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKTKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            complement(30569..31159)
                     /gene="rnmV"
                     /locus_tag="VCX65_000763"
     CDS             complement(30569..31159)
                     /gene="rnmV"
                     /locus_tag="VCX65_000763"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEP5053237.1"
                     /translation="MQRGYLSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEAVPSSKS
                     KGRSLGVEHANFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYEE"
     gene            complement(31131..31922)
                     /locus_tag="VCX65_000764"
     CDS             complement(31131..31922)
                     /locus_tag="VCX65_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEP5053238.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVV
                     GFDQATISGALALADQYPNVYATIGWHPTEAGSYSEAVEESIVSQLSHPKVIALGEIG
                     LDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKETTANAKRVLKLD"
     gene            32207..33037
                     /locus_tag="VCX65_000765"
     CDS             32207..33037
                     /locus_tag="VCX65_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEP5053239.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDASERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNGL
                     "
     gene            complement(33148..34086)
                     /locus_tag="VCX65_000766"
     CDS             complement(33148..34086)
                     /locus_tag="VCX65_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEP5053240.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKKEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMVQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS"
     gene            complement(34108..35022)
                     /locus_tag="VCX65_000767"
     CDS             complement(34108..35022)
                     /locus_tag="VCX65_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEP5053241.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGAISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIVDKDLEKAKTLQYTINETIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLAELVEEDRVICQRAAALINQAKETF"
     gene            complement(35034..35696)
                     /locus_tag="VCX65_000768"
     CDS             complement(35034..35696)
                     /locus_tag="VCX65_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEP5053242.1"
                     /translation="MTSKKQGLLHSLFKLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLVTTYSSHFKHYFKSGMRLGLIELLIMSICVLDLF
                     LIRNQSGLVFQGFKVLCIAVLFLVVILFLYAYPQAVRKELPLLILFKRSLLLAGILFP
                     WTFAFLVVIGLLVFTLPLTLLTLFCGLSLLATMGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            complement(35853..36683)
                     /locus_tag="VCX65_000769"
     CDS             complement(35853..36683)
                     /locus_tag="VCX65_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEP5053243.1"
                     /translation="MTKKKLTASDVLTTVILCILTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            complement(36696..37583)
                     /locus_tag="VCX65_000770"
     CDS             complement(36696..37583)
                     /locus_tag="VCX65_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP5053244.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTDFTFVGFANYARMFQDPIFMKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIAILLTTSVGQPIILYIAAMGNIDNSLMEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            complement(37686..39005)
                     /locus_tag="VCX65_000771"
     CDS             complement(37686..39005)
                     /locus_tag="VCX65_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP5053245.1"
                     /translation="MNMKKLASLVMLGASVLGLAACGGKSQKEAGASKSDTAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTEEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAVSNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            complement(39054..39758)
                     /locus_tag="VCX65_000772"
     CDS             complement(39054..39758)
                     /locus_tag="VCX65_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEP5053246.1"
                     /translation="MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLLAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMAEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAERFIEALKS"
     gene            complement(40032..40166)
                     /gene="rpmH"
                     /locus_tag="VCX65_000773"
     CDS             complement(40032..40166)
                     /gene="rpmH"
                     /locus_tag="VCX65_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEP5053247.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            complement(40481..41395)
                     /locus_tag="VCX65_000774"
     CDS             complement(40481..41395)
                     /locus_tag="VCX65_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEP5053248.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINQKNAPAVNSADVEPEEIKATQKLEAED
                     TKVVPLMSEDSPAQTLSNLAETVTETKAQQPSIPVEESEVPQDPGNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            complement(41407..42234)
                     /locus_tag="VCX65_000775"
     CDS             complement(41407..42234)
                     /locus_tag="VCX65_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEP5053249.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            complement(42200..42559)
                     /gene="rnpA"
                     /locus_tag="VCX65_000776"
     CDS             complement(42200..42559)
                     /gene="rnpA"
                     /locus_tag="VCX65_000776"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEP5053250.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            complement(43099..43839)
                     /locus_tag="VCX65_000777"
     CDS             complement(43099..43839)
                     /locus_tag="VCX65_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5053251.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            complement(43843..45126)
                     /locus_tag="VCX65_000778"
     CDS             complement(43843..45126)
                     /locus_tag="VCX65_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP5053252.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSVIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSATSMMRTNYEISSLDNIKEAVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            complement(45123..>46406)
                     /locus_tag="VCX65_000779"
     CDS             complement(45123..>46406)
                     /locus_tag="VCX65_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP5053253.1"
                     /translation="YIFSFLSDITLPVWKQLTILALALFFNQFPYLSPLLIDPLLFLV
                     VLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVIPYLFLSSGIYLGHIIFDLLAY
                     LLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTLLIFVLVYYVDIFVILGFTDPF
                     LHFHHSLFVPTPYKLLFLMFILLLVYLLSYFNHSSKEYLKNELRREQQAYMTNLETYG
                     KHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQDIYAQTVHEANDYWDDKHYNI
                     SKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNIKETYIPELDLLLLMSIFCDNA
                     IEAALEAQQPHMSIAYFLLDDYQMFVVTNTTKKKVDINKIFEEGYSSKGSERGIGLSN
                     AQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
BASE COUNT        14036 a         9853 c         8432 g        14085 t
ORIGIN      
        1 gaggtttcaa ttagtttaat aaagattgtc attctctcat ggtagcgttt tattgcatca
       61 ctactcttgt gaggtaagtc attaccttag acaaaaatat ggtataatta aaaaaataat
      121 acttgagtaa ggataatcta taaatgatca aacgattaat ttccctagtg gtcatcgcct
      181 tattttttgc agcaagcact gttagcggtg aagagtattc ggtaactgct aagcatgcga
      241 ttgccgttga ccttgaaagt ggcaaagttt tatacgaaaa agatactaaa gaagttgtcc
      301 cagtcgcctc agtcagtaag ctcttgacaa cctatctggt ttacaaagaa gtttctaagg
      361 gcaagctaaa ttgggatagt cctgtaacta tttctaacta cccttatgaa ctcactacaa
      421 actatactat tagtaacgtt cctcttgata agagaaaata taccgttaaa gaacttttaa
      481 gtgcgttagt tgttaataac gccaatagcc ccgctattgc tttagctgaa aaaataggcg
      541 gaaccgaacc caaatttgtt gacaaaatga aaaaacaatt aaggcaatgg ggcatttccg
      601 atgcaaaggt cgttaattca actggcttaa ctaaccattt tttaggagct aatacttatc
      661 ctaatacaga accagatgac gaaaattgtt tttgcgccac tgatttagct attattgcca
      721 ggcatctctt attagaattt ccagaagtac tgaaattatc tagcaaatcc tccactattt
      781 ttgatggaca aaccatttac agttataatt acatgcttaa aggcatgcct tgttatcgag
      841 aaggcgtgga tggtcttttt gttggttatt ctaaaaaagc cggtgcttct tttgtagcta
      901 ctagtgtcga aaatcaaatg agggttatta cagtagtttt aaatgctgat caaagccacg
      961 aggatgattt agctatattt aaaacaacca atcaattgtt gcagtacctt ttaattaatt
     1021 ttcaaaaagt ccagttaatt gaaaataata aaccagtaaa aacgttatct gtcttagaca
     1081 gtcctgaaaa aactgtcaaa cttgtagccc aaaatagttt attttttatc aaaccaatac
     1141 atacaaagac caaaaatacc gtccatatta ctaagaaatc atccacaatg atcgcacctc
     1201 tatcaaaggg acaagtctta ggtagagcaa cccttcaaga taaacatctt attggacagg
     1261 gttatctgga tactcctcct tctatcaatc ttatccttca aaaaaacatt tctaaaagtt
     1321 tctttttaaa ggtctggtgg aaccgttttg tgaggtatgt caatacctct ttatagaata
     1381 acacaatgct ttttgtatga cattgactga cagagtactt ctgcagtctt tttcattttt
     1441 atttaagcaa actaggccaa tcctaacaat ttttcaaaaa aacttcacat tgtattagca
     1501 aagtgatata ctgaaaatgc attacattta aaggagtcgg aaattgacca aaagaattat
     1561 actaactatt tttaccttta tttgcttttc ggtgatgcct cttgtccaag ccgaagatgt
     1621 catggatatt acaaggcaag caggctacac agttagtgag gttaatcgac caaaatcttc
     1681 tattgtcgtt gatgcaaata gttcagatat tctttggcaa gataatattg atattcctag
     1741 ggatcctgct agtatgtcta aaatgtttac gctttacatt ttatttgaag agctcgctaa
     1801 gggaaaaatt acgatggaca ctactattac ggcaactcca accgatcaag ctatcgctaa
     1861 catttatgag attagcaata ataatatcgt cgctggagta gcttatccta ttcgtgatct
     1921 tattactatg acagctgtgc cttcatcaaa tgcagcaact gttatgattg ccaattattt
     1981 atcaaacaat gatgcttctg cgtttatcga tcgtattaat gccacagcca aacaattagg
     2041 catgactaac actcattttt caaacgctag tggtgcagca gcacaagctt ttcaaggtta
     2101 ttataatcct actaaatatg atttatctgc ttcaaatatt acgaccgctc gagatttgtc
     2161 caagttactc tatgccttct taaaaaaata ccctgaaatt atctccttta caaataaatc
     2221 tgttgtgcac actatggtag gaacgccata tgaagaagaa tttcacacct ataaccactc
     2281 tctcccagac aatcaatttg gtatgaaagg agttgatgga ttaaaaacag gttctagtcc
     2341 cagtgctgct tttaacgcca tgataactgc caaaagaggc aaaactcgac tcattactat
     2401 tgtcatgggg gtcggagatt ggtcagatca aaacggagag ttttatagac atcctttcgt
     2461 taatgccttg actgagaaag ggtttaaaga tagtaagacc ttatccaaaa aagcacgcca
     2521 aaaactcgaa aaattagtgc cacaaaccaa aaaagaaaca tcacctaaac agcagcactt
     2581 caaagccact aaaaagcaat cgtacttgga aagagtcgaa gattttatga atcacaacca
     2641 cactttcttg cttatttgct tagctatctt tataattact atccttttac taagcctcgt
     2701 tgtctttgca atgggacgcc aataatgaat tatcaaaaac ctctgtcaaa gcacagaggt
     2761 ttttgatatg ttatcttacg tgttcaaggc aactaaaaac taaccacttg gggttagtac
     2821 tacaactcat aaaatcctat ctcaaagatc tttcagatgg ataagagaaa atgcaattaa
     2881 ccgacagaac cttccatctc ataggaaatc aatcgattga gttcgaccgc atattccatt
     2941 ggcaattctt tggtaaaagg ctccacaaat cccatgacaa tcatctctgt ggcttcgctt
     3001 tctgataagc cacggctcat gagatagtag agttgttctt cagaaatctt agacacttta
     3061 gcttcatgtt ctaacgccac ctgtgaatta tgaatttcgt taaatgggat cgtatctgat
     3121 ttagaaatat cgtccatcaa aatagtatca cattcaatat gggaaacgga ttttttagat
     3181 tgcttgttaa aggtcacttg gccacgataa tctactttac caccagactt ggcaattgat
     3241 tttgacacaa ttgatgatga tgtatgggga gcattgtgaa tcattttagc ccctgtatct
     3301 tggtgttggc ctgcgttagc aaaggcaata gacagcatgg tgccacgcgc acctggccca
     3361 tcaaggtaaa cagaagggta cttcatggtg gttttagctc ctagattgcc atcaatccat
     3421 tccactgttg catccgtaag ggcgcgtgca cgttttgtta ctagattata cacattgtct
     3481 gaccagtttt gaatggtggt ataacgcatg tatgcaccgt caagcgcaaa gatttcaacg
     3541 atagcagcat gtaagctgtt acttgaataa gtgggagctg tacatccttc aacataatga
     3601 acacttgctc cttcatcaac aataatcaat gtccgctcaa attgaccagt attttcattg
     3661 ttaatgcgga aataagtttg caaagggata tctaccttga cccctttagg aacataaata
     3721 aaggtaccac cagaccaaac tgctgaattg agggctgcta atttgttgtc tgttggcgga
     3781 accagtttgg caaagtattg tttgaacaaa tcaggatatt ctttgagggc ggaatcggta
     3841 tctgtaaaga taatccctag cttttcaaat tcacccttca tgttatggta aaccacttct
     3901 gactcatact gagctgatgc cccagcaaga taagcacgtt ctgcttctgg aattccaata
     3961 cgatcaaagg tttcttttat tttttctgga acatcatccc aagaacgagc tggcttatca
     4021 gatgcttttt gatagtaaat gatatcatca aagttaatat ctgataagtc tgctccccag
     4081 gtttgcatcg gcattttatt aaaggtttcc aaggatttta aacgaaactc caacatccac
     4141 tcaggttcat ttttggcagc tgatagttcg cgaaccactg cctcactcaa tccttttcct
     4201 gtagaataaa tgggctctac atcatcgtga aatccaaatt ggtagtcccc taagtcaatt
     4261 ggctttggct ctactttctc atttatatca gacatttttc ccttccttta cattttggtc
     4321 cgtgaggtgc tgagcattgg cacttcgttt aatggcttcc ttgagagcat tccaagctag
     4381 ggtagagcat ttgatacgct gtggaaattt tgcaactcct gccaacaatt ctgcttcacc
     4441 tagctctttt tgagcaggat tttcctgtcc ttgtaccatc tctgaaaaaa tatcagctaa
     4501 cgcgagtgct tcttctttac ttttaccaat aacagcatct gtcatcatgc ttgatgaagc
     4561 tgtggaaatg gtacagccgt tgcctgcaaa agcaatatct tcaattttat cttcgtcaaa
     4621 cttaacggtc aaagaaatca catcaccaca agtcggatta ttcagttgaa cagcctctac
     4681 gccatctagt tgcccatgat gatgtggacg tttcgaatgg tccgctacca cagccatgta
     4741 tagatggttc agtttagaga gtgccattga aaaactcctt tgcttttaga attgcttcga
     4801 ctagacggtc acaatctgcc ttggtgttat agatataaaa acttgctcta acagttgctg
     4861 gtacacctaa ataactaaga agaggttggg cgcagtggtg ccctgctctt actgcaacac
     4921 cttcatagtc caaggctgtt gccaagtcat gaggatgcaa atcatccaga ttaaaagaaa
     4981 tcagaccaga tcttgcacta ggctggcttg gtccatatat ggtaagcccc tcaatagctt
     5041 ctaatttcgg caagacatag gctattagtt ctgcttcatg cgcatgtata tcagccatgc
     5101 ctagtctctg aaggtaagaa atggctgcgc ttagcccaat agcaccagct atgtgaggtg
     5161 ttcctgcttc aaacttccag ggcaattctt tccaagtggc ctcttgttcg taaacaaaat
     5221 caatcatttc tccgccaaat tcaagaggct ccacttgatt caaaagctct tctttgccgt
     5281 aaagaacacc caaacctgtt ggccccaaca tcttatgagc tgaaaaagca aagaaatcac
     5341 aatccaagtc ttgaacatca atagccaaat gtggaaccga ctgggcaccg tcaacaacaa
     5401 ggtaggctcc tttagcatgt gccagcttgg caatttcttt aatgggattg atgcaaccaa
     5461 gaacattgga gacatgtact aggctaacaa aacgtgtttt tgtcgtcaat ttgtttgcca
     5521 aatcgtccat gtcaagttgg ccatctttta aataaacata gactaacctt gctcctgttt
     5581 tttgacaggc ttgttgccaa ggaatgatat tggcatgatg ctccataatc gaaatcaaca
     5641 cctcatcttc tggcgtcaag acctgctctg caaaccgagc aacccaattc aaactggttg
     5701 ttgttcctct ggtaaagagc acttccttac ttgatttagc atgaataaag tcagcaacct
     5761 gctggcgact ggcctcatat ttgtgcgttg cacgttcagc caaggtatga actcctcggt
     5821 ggacattagc attatcttct tgataatagg attgcaaagc ctcaagaaca agcgccggtt
     5881 tttgtgtggt ggcggcatta tccaaataaa caaggggttc atcattgact tgttgattta
     5941 agatttgaaa gtcttgtttg atgtcttttg cgtctagcaa tactaacctc tttctttttg
     6001 gcagtaggtc ttaacgatta agcaatttct catctaaaac cttaataatc tcttggtgga
     6061 ctgatggaat aggaatttca gcgataactg ctcctaggaa tcctctaata accaatcgtt
     6121 ctgctgtttc ttgatccagt cctcgactca tcaagtaata catatcttca gggtcaacct
     6181 gaccgataga agctgcatga cctgctgtta cttcattttc atcaattaag aggattggat
     6241 tggcatcggc tcttgcttgg tcagaaagca tcaaaacacg gctttcttgt tgagcatcag
     6301 ctcccttagc gccttttaga atatgaccaa tcccgttaaa cgttaaggtg ccacgttcca
     6361 aaatcacacc atgctgtaaa atatgaccga ccgtacgttg accatagttg gtcacgcgcg
     6421 tgtcaatacc ttgtacctga cgaccacttg aggctgcaac aactttcaaa tcagcttgtg
     6481 agccctgacc aatcaaatca ctgtcaaaat cagcaatgac attgccttca ttcatcacag
     6541 ctaaggccca atcaatgttg gcatccttct ctaaacgtcc tcgacggcta atataggttg
     6601 tcactgaagg acctaagcgg tcgatagccg agaatttaat ctggctgcct gcttgggcaa
     6661 tcacttctac actgatatta gcgctggtct tttgagtggc attgccaata gattcaaaac
     6721 gctctaaata ggtgaactta ctttcttttc ctgcaatcac tagaacatgc ttgttaaaag
     6781 gaacgtcact gtcactatct tgtaagaaaa tagcttcaat aggagttgtg atttccaagt
     6841 gatcaggaac gtagagcacg gctgcgctat taaaataagc agtgtggtag gcagctagtt
     6901 tgtcttcatc aaaagctaat gcctgaccaa aatgagcttc aattacttct gggatttcct
     6961 caagcgccgt ataaaaatca ctgaaaacaa ctcccttgtc aattaacgcc attggtaact
     7021 gttctaagac tgtttgcgtg cctacctgaa caagctttgg gttatctcca atagctataa
     7081 aatctggaac actagctaga ctttcatttt ctgttaaggt accatctcct agattccaac
     7141 ggtgaaattt aaccctttcg atggttggta actctaattc tggtatggct tctaatgccg
     7201 ctaaacgccg ttcttgcagc caagcaggct cagcgtgggc ttgcgaaaaa gctactagtt
     7261 tttcttttgt catctgtcaa tcctttgtct ctggttttta aattggctgg gtatatagaa
     7321 catcacctag ctttttgtag aaagctaaag taattgtctc caaaaactta actttcttcc
     7381 ttatactcga ttcccagatc ctgtgcaata cctgcgtagc cttctttttc aagacgagta
     7441 gccaaggcag catcaccaga taagacaata cgaccatcca tcataacatg aactaggtct
     7501 ggggtaatgt aattcaacaa acgttgatag tgggtgataa tcatagctcc aaagtctttc
     7561 ccacgcatct cattaacccc tttagagact acttttaggg catcaatatc aagaccagaa
     7621 tcaatttcat ctaacaaagc aaatttaggc tctaacatga gcaattgaag aatttcattg
     7681 cgttttttct ccccaccaga aaaaccttca ttgaggtaac gctctgccat ctcttctttc
     7741 atacctaaca aagccatttt ctcatcaagt ttggtgataa aatctcgcac ggaaatctta
     7801 tccttatctg ccttaccggc attcattgct gcacgcataa attcagcgtt ggtaatccct
     7861 ggaatttctg aagggtattg catggcgaga aaaagtccca gtctcgcacg ctcatcaact
     7921 tctagatcga gaatattgac cccgtcaagc aaaatttgcc cttgggtcac ttcgtagtta
     7981 ggatttccca taatagctgc tgaaagggta gactttcctg tcccatttgg ccccataatg
     8041 gcagctactt ccccagtttt aagagttagg ttaacccctt tcaaaatctc tttaccttct
     8101 attgaaacat gtaaattatt aatctcaaga attgacatga tacacccctt attttctctg
     8161 tcatctatac catctcaaga aaagacagtg tcatttgcac tgcttttttt ataatggtca
     8221 ctgcatctat tatagcaaaa aaagccttac tcggcttttt tagtgtttca aatccttctt
     8281 ttctttccat ttcagaagca ttgcttgacg ataatcacta ttaccaataa actttaacaa
     8341 gttaaacaaa ggcgttcgct tttcacccca gatctccaat ccttcaataa aaacttctaa
     8401 accaaataaa agtccaagca tcaagaggac gccaccaatt cgactagaaa catttaaaag
     8461 taaagaaata agggaaaaaa gcatggtaat accataaact actaagacag ctcctcgatg
     8521 agtaaagccc attgataaga gtcgatgatg caggtgcatc ttatccggct cgtagaattt
     8581 ttgacctgat aaactacgtc gaataatagc cacgatggta tccataatgg gtacaccaag
     8641 aataataaca ggtgtcacca cagccacagc cgttgaattt ttcaatcctt gaagagacaa
     8701 aacccctatc ataaagccaa taaagagggc tcctgtgtca cccaaataaa tcatagctgg
     8761 atggtaatta taaggaaaaa atcctgcaat agcagaaatc aagaccaaaa tggttaacgt
     8821 caaaaagaaa tccttttgag gtaaaaagaa ataagataca atagccatgg tcactaaact
     8881 aataatagag accccactaa ccaaaccatc caaaccgtca atcaagttaa tagcattagt
     8941 gatggaaaca atccacagga ctgttaagaa taaggttaag aaaggaccaa aaactaacaa
     9001 cggccctcca aaaggaattt tgaagctatc aaatttaaag tcggtaaaag cccagacaat
     9061 cactgcacca attagaatac caaacatctt taatttagga cttaactcat acaaatcatc
     9121 taaaaaacca gtaagggtaa ttactgtagc accaatcacg acaggtaaaa tataactgaa
     9181 gtaggtctga ccaaaaaaca tggcgccttt agaagcaatc ggaataagtc ccaaacttgc
     9241 tactaaaaaa gacataaaaa tagctaatcc accactggtt ggcatcggaa ccttattgac
     9301 ccgtctggca ttgggattgt ctactgcacc cacacgaaag gctaaaaagc gaacaagagg
     9361 ggttaagaat aaggacatta acaaagcccc tatcagaaca aggacataat ctattgtgaa
     9421 tgaaaacata ctattttatc ccaactcaat cttttgtaat tgctcaacag caccatcaag
     9481 catcaattgt aagccatgct cttgtaaata agctcttgtt tttgatccag ggtttgcatg
     9541 ctcaatcaat ctcgcataca tgacattcgc aaaataagat ggttgttgct gaacatctaa
     9601 taaaatagtc atatggtagc agttgctccc cttatataac tctgaagctt ctatcgaaaa
     9661 atcaatcgtt ttagcaaaag ccactgcctc tgtaatcgtt gaaaaatcca atacataatg
     9721 gacatagtct aaaggttctg actcatgatt agttgatgga tcagccgcct cagactgatt
     9781 agctagagta gcttcaacaa catcttccat tatctcttca attttttcca atttttcatg
     9841 agctttgaca tctccctttt cacgcatgga ttgctccaag ctcttgaaaa aatcttccgg
     9901 agtcatttgg gacatatcac caaactctgc taaatcttca agattaatat ctttatttat
     9961 ctcagatttg gtaacaaaaa catctagacg gtccttgcgt ggagtcactc gaaaactaag
    10021 cataccacta tctttaaaat tatctggaag atcgagttcg tccatcacag aatagaaaaa
    10081 ctcttctgtt ttttcttgag gaatcaagaa atctttcaac tccattcctc tttcttctaa
    10141 atcgtccata ctaattgtta tttttagcgt tgtctcgcta atttgtttca tttccattct
    10201 caatacctcg cacgcgtagt cattttatta tactagaaat gctgtaattt cgcaatttat
    10261 gactaactcc tcttctccaa aaggaaattt aaaaagcgac agtccccaag gtctgtcgca
    10321 acatcctaaa cgatatgtaa gtttaaaaaa caaatttaaa gaagctataa ataagtaaaa
    10381 ggcttcctaa cacaatacgg tatttcccaa aaatggtgaa atcgtgtttc ttaacataat
    10441 ctgtcaagaa cctaatcgcc aataaactaa ccacaaaagc ggtcaaacta gccactaaaa
    10501 gaataaggac ttgtgcaaaa tcaaggtgat ggccatcaag gaaaaatttc acagccttta
    10561 atccactata tccaaacatg gtaggaatgg ccaaaaagaa ggtgaaatca gcggccactg
    10621 ttcgactagt tcctaaaata atagctccta agatggtagc ccctgatcga ctagtaccag
    10681 gcacaatact taagacttga aaacaaccaa tgaagaaagc tgttttgtaa gacattctag
    10741 ctaattcagt gacggcaggt tcttgttgag catttcgttt ttcaatccag ataaaggcaa
    10801 tcccgtagac gattaaagcg atggcaatcg gaaccataaa ataaaaatgt gcttcaaacc
    10861 aattatcaag aggaaccgct attaaaatag aaggaataca cgcaatcacc acttttagcc
    10921 ataattgcca ggtaagctgt acttctcttg ctgttttccc aggttgaaag ggattgagac
    10981 gttcaaaata aatcaacata acagcgataa tcgcccctaa ttgaataacg atattaaaca
    11041 tttctataaa agccttatcc tgatttagtc ggataaattc ctgcaccaaa atgaggtgac
    11101 cagtgcttga aactggtaac cattctgtga ttccctcaat gatgccaaag aaaatggctt
    11161 ttagcaattc gataattaac atgttttctc cttattaacc actcttattg tgattttcta
    11221 aactgtgatt aatgccaagc agctttttta aaaggcaccg ccgccgcctc ctccgccacc
    11281 gccagagaag ccgccaccac cactaatccc gcctccggaa gagactgaga aatttgagga
    11341 agttgtagct gaagacaagc tagacaaaaa ggttggtgtc gtagcataca ttaccattga
    11401 taattcaccc ggtcgaacag cttggtaaac ctcaggtaag gcaatacgat ggactttcaa
    11461 atagcgttcc actttcttag cgtaaccaaa taaggtggca taaaccaaaa cacggttcca
    11521 aacaaccaaa ccttcaatag caacatcctc aaatttgtca atgtctcgta tcatgttttt
    11581 aaagctctgc cattgatgta accgaacacc cccctcaggt gtttcaatac ccaatttctt
    11641 gtattgatct aacttcaggc taatgtaaaa gccaaggcac atcgttagca ccattaaagc
    11701 aaggtaaatg agggctaacc cactttcttt aatagccaag taaatcaata aaccactatt
    11761 tagaacaagc aacaaacaac ctaatccctg gacactattg ctttttcgtt tctctgccgg
    11821 ggtcatttga cgataagtat ctggtaagtt taactttttg atagtttcta ggacattgtt
    11881 tgtaatagct gccgacgctt ttttcatcgc cttaatcacc tgctcagacg attgacggac
    11941 ttcttgctcg agctttttac ctttgtacgt tttctttaat tgtttaatgg tatcagcatc
    12001 ataatggtat tgactaaaca attgatccac cggcaatgtc accttgtttc caaaagccat
    12061 atctaagaag gcagcttcct catctgtcac acgatctaac tgactgattt caagataagc
    12121 tttcccttct tctttcgtta ataaaagcac cttttggtcg atcagatcca acaaggtagc
    12181 ttgaacaagg gcctcaaagg tcactccttt agggatcaat aatttctggc tttctgatgc
    12241 tgtaggggat aaataggcaa aactctgtcc ataaatcgct tgtgtcaaca caagaggcga
    12301 aagatcttca gggacttcgt aactgtgatc tgtatggttg gccaaatgat aacgattgaa
    12361 ttgtttcttt aatcttataa actgtattaa ctgccacaga agaaaaccta cctctaccag
    12421 aggaatgact ttgccaaata gcagctgtaa caaggccctt cgtctggaaa tcttagtttc
    12481 caacgctaca attttattct ttttactcgt tgaaacatca actggttctt ctcccaataa
    12541 tgctttttta tcccaataag catgcaattc caattgccct gagacatttt tggcattaat
    12601 ctgatagcga ctgttacctt cttttaacac ttgaggtttc ttttggtaat atcctctgtg
    12661 agcccataga ttagaatcct gaatatcagt tggggtagtg acggtcaaac tcaccttttc
    12721 taatgttttg tcccaatcac taatcggtgt ccaattcagc tctgccacgt cttgataagc
    12781 tgttaaaagg tggtgcagtt gccagataac cttaacgtca accttatcac cagcttggcc
    12841 agcattataa agttttaaac gatagccatc tccaaggtca ctaaactctt gactaacagg
    12901 tacctgttga ccattctgat atacctcaac tttaggcttt tggtcaatag caaagcccgc
    12961 tggcaaatga cctgcccggc ccagcgaaat atactggccg ttataagaag tgtcaaattg
    13021 ataggttact ttttgctcaa accgagcagt attttctttt gataacagta actgaccttc
    13081 atagttggtg atgctatagt ctacatcagc tgcttttatt cgtatcccta aaagactgaa
    13141 gcagagcaca agcgtcatca aaattttttt catggcaaca tcctctttct gccctcattt
    13201 taccatattt taaggagatg acaaaaccta aaccaagtcc ttcatcttat ttttaatcat
    13261 tattttgaat atttttccat atttcaacct attcactgat aatatattga aataggatgc
    13321 aaattgctgt aaaataggtc tgaatactat ttttgaaaca ggagacctat atgaaaaagc
    13381 taatccttag ctgtttggtc gccttggccc ttctgtttgg aggaatgagc cgggctcaag
    13441 caaaccaata tttaagagtc ggaatggaag cagcctatgc tccttttaac tggactcaag
    13501 atgacgcttc aaacggggct gtccctattg agggaactag ccaatacgcc aacggttacg
    13561 atgtccaagt cgctaaaaaa gtcgctaaag ctatgaacaa agaactgtta gtcgttaaga
    13621 cctcttggac cggtttaatt ccagcattaa cttctggaaa aatcgatatg atcgctgctg
    13681 gtatgagtcc taccaaagag cgtagaaacg aaattagctt ctcaaacagc tactacacta
    13741 gccaacctgt tctagtcgta actgctaatg gcaaatatgc tgatgcaaca agcctcaagg
    13801 atttttctgg agctaaagta actgcccagc aaggcgtttg gcatgtcaat ctcttaactc
    13861 aactaaaagg tgctaagtta caaacaccaa tgggagattt ctctcaaatg cgacaagccc
    13921 ttacttcggg tgttatcgat gcctatattt ctgaacggcc tgaagccatg actgctgaag
    13981 ctgctgatag ccgtttgaaa atgatcactc ttaaaaaagg gtttgctgtt gctgaatcag
    14041 atgctgctat cgctgtcgga atgaaaaaaa atgacgatcg tatggcaact gtcaaccaag
    14101 tgcttgaagg attttctcaa acggatcgta tggccctgat ggatgatatg gttaccaaac
    14161 aacccgtgga aaagaaagcc gaagatgcta aagcatcatt tctaggccaa atgtgggcta
    14221 ttttaaaagg taactggaag caattcttac gtggaactgg aatgaccctt ctgatttcca
    14281 tggtcggaac cattacaggt ctctttattg gattattaat cggtattttc cgtacagctc
    14341 ctaaagctaa gcataaagta gctgccttgg gacaaaaact ctttggttgg ttactcacta
    14401 tttacatcga aatcttccgt gggacaccta tgattgttca atctatggtt atttactacg
    14461 gaacagcgca agcctttggt atttcgatcg accgtaccct agcggctatt tttatcgtat
    14521 ctatcaatac gggtgcctat atgagtgaaa ttgttcgcgg tggtattttc gctgtcgaca
    14581 aaggtcaatt cgaagcagca actgctcttg gctttactca cggacaaacc atgcgtaaaa
    14641 tcgtgctacc acaagttgtt cgcaacattt taccagcaac aggtaatgag tttgtcatca
    14701 atatcaaaga tacttctgtt ttgaatgtta tctctgttgt ggaactttac ttctcaggta
    14761 ataccgtagc cacacaaacc taccaatatt tccaaacctt tacgattatc gccattatct
    14821 actttgttct taccttcacg gtgacacgta ttcttcgtca tattgaacgc cgtttcgatg
    14881 ccgatactta caccactgga gcaaaccaaa tgcagattgc ggaggtctca aatgtctaac
    14941 tcaattattg aaatcaaaaa cctcaaaaaa tcttacggca gcaatgaagt actcaaagat
    15001 atctcccttt ctgttaacaa gggagaagtg atttccatta tcggttcttc tggttctgga
    15061 aaatcaaccc tcctgcgctc gatcaatctt ttggaagagc caagtgccgg tcaaatcctc
    15121 tttcatggtg aagatgtcct tgctgaacac tacaacttga ctcactaccg tgaaaaacta
    15181 ggcatggttt tccaatcctt taacttgttt gaaaacctaa atgtattgga aaatgctatc
    15241 gtcgctcaaa ccaccgtcct caaaagagac cgtgcacaag ccgaacaaat cgctaaagaa
    15301 aacctcaatg cggttggtat gacagaacaa tactggcaag ccaaaccaaa acaattatca
    15361 ggggggcaaa aacaacgggt tgccattgcc agagccttat ctgtcaatcc agaagccatg
    15421 ctctttgatg aaccaacatc agctcttgat cctgaaatgg ttggtgaggt ccttaaaacc
    15481 atgcaagact tggcaaaatc agggttgacc atgattattg ttacccatga aatggaattt
    15541 gctcgtgatg tttctgacca tatcatcttc atggataagg gattgattac tgaagaagga
    15601 agtcctcaac aaattttcga gaatcctaca caagatcgta ccaaagaatt tttacaacgc
    15661 ttcttaaaat aagataaagg atccaactat ttctatgcca gttgggtctt ttttcaattc
    15721 aaaaagaatt tgtcataaaa tactttacca gttaactatt ttatgctata cttatttttg
    15781 ttaacgttaa taatttatat ttaggaggat aatatggcag aaaaaactga cttatcgtca
    15841 gcttacagaa gactgaaaag tcccaatatt aaaaccagaa aacgtgctct gaagattatt
    15901 cacgagtaca aacgttacgg taaaaaataa gattttactt tttatctctc caaatttaag
    15961 tcagacaaaa aaaggctaag acaccccttc catcttagcc tttttgtata cagtttatta
    16021 agggaactat tttaaaatat cttttatgct agagtctaga atagttcaaa acgttaaaat
    16081 catacattta aggtagtgtt taaagtatac gaaaaagaac tcagcataaa ccaagctctc
    16141 tttcgttata actaattatt tagcaatttt tgcgaagtac tcaagagtac gtacaagttg
    16201 agcagtgtaa gacatttcgt tgtcatacca tgatacaact ttaaccaatt gtgatccgtc
    16261 aacttccatt actttagttt gagttgcgtc aaacaatgaa ccgtatgata cgcctacgat
    16321 atctgaagaa acgattggat cttcagtgta accgaagcta tcgtttgaag cagctttcat
    16381 agcagcgttg atttcgtcaa cagaaacgtt tttgtcaaga gttacaacca actcagttac
    16441 tgatccagtt ggaacaggaa cacgttgtgc agcaccgtca agtttaccgt taagttctgg
    16501 gataacaaga ccgatagctt tagcagcacc agttgagtta ggaacgatat ttgcagcacc
    16561 agcgcgtgca cgacgaaggt caccaccacg gtgtggtccg tcaaggatca tttggtcacc
    16621 agtgtaagcg tggattgtag tcataagacc tttttgaata ccgaatgcat cgtgaagagc
    16681 tttagccata ggagctaaac agtttgtagt acatgaagca cctgagataa ctgtttcagt
    16741 accgtcaaga atgtcgtggt tagtgttgaa aacaactgtt ttaacatcgt ttccaccagg
    16801 agctgtgata acaacttttt tagcaccgtt agcatgtaag tgtttttcag ctgcttcttt
    16861 tttagcaaag aaaccagttg cttcaagaac gatttcaacc ccatcagttg cccagtcgat
    16921 gttttctgga tcacgttcag cagaaacttt gatgaagttt ccgtttactt caaatccacc
    16981 ttctttaact tcaactgttc catcaaaacg accttgagtt gtatcgtatt tcaacaagtg
    17041 tgcaagcata tttggatctg taaggtcatt gatacgagtt acttcaacac cttcgatgtt
    17101 ttgaatacgg cggaatgcaa gacgtccgat acgaccgaaa ccattaatac caactttaac
    17161 taccattagt gatttcctcc ttatgaaaat caaaagaata ttatttagag ggaatgctcc
    17221 ctacctattg tgaaaagatt aacttacagt catctgcaac aacctttcaa cagaactatt
    17281 atataactat ttcagaaaaa atgcaaataa attagccatt ttcataaagg gcagcttctt
    17341 tcttctagcc ttcaaaaccc accaaatata ggaaagggct ttcttttttc tatgttctat
    17401 tctgtaattt atctttttat tgggaaagat ttccaaaact tcaaactgta ctataacgtt
    17461 ctgttacact aaaaaagagg ttaggatagt tatcctcaac ctcttagtgg tggttattca
    17521 cctttgtttt tcttaatgat ttcttcttga actgacttag gaacatcttc atagtggtca
    17581 aataccatca tgaatgtacc acgtccttga gtagcagaac gaagaactgt tgcataaccg
    17641 aacatttcag caagtggaac ataagcacga acgatttggc tgttaccatg tgcttccata
    17701 ccgtcaacgc gtccacgacg agctgtcacg tgtcccataa cgtctccaag attgtcttct
    17761 ggagctgtaa tcgttacaag catcatcggc tcaaggatag ctggttgtgc agatttagct
    17821 gcttctttaa gtgcaagtga tgcagcgatc ttgaaggcag tttcagatga gtcgacatcg
    17881 tggtatgaac catcgtaaag cttagcttta acatcaacca ttgggtaacc tgcaagaaca
    17941 ccgtttgcca tagattcgat caaccctttt tcaacagctg ggataaattc acgaggaact
    18001 acaccaccaa cgatagcatt ttcgaattcg aaacctttac cttcttcatt tggtgtaaat
    18061 tcaatccaaa catcaccgaa ttgaccttta ccaccagatt ggcgtttgaa gaatccacga
    18121 gcttgtgtag aagcacggaa tgtttcacgg taagatactt gaggagcacc aacgttagct
    18181 tcaactttga actcacgttt catacggtca acaaggacat caaggtgaag ttcacccata
    18241 ccagcgataa ctgtttcacc agtttcaacg tttgtttcaa cgcggaatgt tggatcttct
    18301 tcagcaagtt tttgaagggc aacacccatc ttgtcttggt ctgctttaga ttttggctca
    18361 accatcaact ggataactgg ttctggaact tcgattgact caagaataac ttttgctttt
    18421 tcatcagtca atgagtcacc agttgttgtg tctttcaaac caacagcggc agcgatgtca
    18481 ccagcgtaaa ctgtttcaat ttcttgacgg ctgtttgcgt gcatttgaag gatacgtccg
    18541 atacgctcac gtttaccttt tgatgtgttc ataacgtaag aaccgctatt aagaacacct
    18601 gagtaaacac ggaagaatgt caaacgacct acgaatgggt cagtcatgat cttgaaggca
    18661 agagctgcaa atggctcttc atcagatgct ggacgttctt cttcagcatc tgtatccggg
    18721 ttaacacctt tgattgcagg gatgtcaagt gggcttggaa ggtatgcgat aaccgcatca
    18781 agcatcaatt gaacaccttt gtttttgaag gcagaaccac aaagtactgg gaagaattca
    18841 acgttgattg ttgctttacg gataccagca atcaattcgt cgttagtgat ttcttcacct
    18901 tcaaggtatt tcatcatcaa gtcttcatca gtttcagcaa ctgcttcgat taatttttca
    18961 cggtattctt gagcttgttc taagtattct tctggaatat cttcttcaag gatatctgta
    19021 ccaaggtcgt tggtatagat ttctgctttc atcttgatca agtcaatgat accacggaaa
    19081 tcatcttctg caccgattgg caattggatt gggtgtgcat ttgcttgaag acggtcatga
    19141 agggtttgta ctgagtaaag gaagtcagca ccgattttat ccattttgtt ggcgaaaacg
    19201 atacgtggaa caccgtattc agttgcttga cgccaaactg tttcagtttg aggctcaaca
    19261 cctgattgtg agtcaagaac ggttacagca ccatcaagaa cacggagaga acgttgtact
    19321 tcgatggtga agtccacgtg tcctggtgtg tcgatgatgt taacgcggtg accatcccat
    19381 tgagctgttg tagcggcaga agtaatagtg ataccacgtt cttgctcttg ctccatccag
    19441 tccatttgtg atgcgccttc gtgtgtttca ccgattttat gaattttacc agtgtagtaa
    19501 aggatacgct ctgttgtagt tgttttacca gcatcgacgt gagccatgat accgatatta
    19561 cgagtttttg caagtgaaaa ttcgcgagcc atgtgtttct cctatttttt tagtttactc
    19621 tttcattata gcactattta gcaaaaacgg ataggcagga cctacccgtt atctaaatat
    19681 ttgttggtaa agataatacc tattgccttt ataaggcttg gtatcttatt cattgaactc
    19741 aggctaaacg ctgtgtgaaa aagataaact ttcctagaga caaaggtttc ttcgtcaaat
    19801 ttcctatttt cactttgcgt tctatacgcc ttcgtatctt attaattgag ttcgagctac
    19861 aagccactga caaaaagata atagttccta gaaactgaag tttctgcgtc aatttcccta
    19921 ttttgtctag catttgtttg acgctaaaat atcttatatt accaacggaa gtgagcaaag
    19981 gcacggttag cttcagccat tttgtgagtg tcttcacgtt tcttaactga tgcacctgtg
    20041 ttgtttgcag catccatgat ttctttagca agacgatctt tcatagtgtg ttcaccacga
    20101 gcacgtgatg cgtttaccaa ccaacgaagt ccaagtgttg tacgacgttc tggacgaact
    20161 tcaactggga cttggtagtt agaaccaccg acacggcgtg cgcgtacttc aagtacaggc
    20221 atgatgttgt ccatagctgt ttcaaatact tcaagagcgt catttcctgt tgcttctttg
    20281 atagcgctga aagcatcgta aacgatagta gcagctgtac cacgtttacc gtcaagcata
    20341 acacggttga taagacgtgt tacgattttt gagttatata atggatctgg taatacttcg
    20401 cgtttaggcg cttgattttt acgactcatt ttctcttatc ccccttctat tatccttttg
    20461 gacgtttcgc accgtattta gaacggcctt gtttacggtc agcaacacct gcagtatcaa
    20521 gtgcgccacg aacgatatgg taacgtaccc ctggaaggtc ttttacacgt ccgccacgga
    20581 taagaacaac gctgtgctct tgcaagttgt gtccgatacc tgggatgtag gcagttactt
    20641 cgataaggtt gctcaaacgt acacgagcga atttacgaag ggctgagtta ggttttttag
    20701 gtgtcattgt tccaacacga gtagcaacgc cacgtttttg tggggcagcc attttagttt
    20761 gaactttttt gtgactgttg taaccaatgt tcaaagctgg tgaatctgat ttttcaattt
    20821 tagatttacg tggtttacgt accaactggt taattgtagg catctacatt ctcctgtgtt
    20881 tttttatttt tggttgatat agcacttggt gacagcccat atccggtgca ctttttgcaa
    20941 caattgtcag cacgtctctg tacacttttg agagaccaaa agtaaaaagt accgtctaat
    21001 ataataacac agacggtact tcatgtcaaa tagaattttt cctttgatgc aattgcttat
    21061 gacgaatgca tcacttagat tccttacgga acctaaatcc tgtgaggccg acagctgcca
    21121 acatgacgac tcctgcttta agagctcttt gagtactttc atcaacatca gaaatgagat
    21181 tgctcgttgt agaagatcct gagccataag atgtcttaga tgagggctga gtaatcgaag
    21241 atgtgatttt agacacaatg gcattacttg ctaccatttc agaggtttgg ccaacaagcg
    21301 cttctgctac aagacttgta ttttcagcag ctaatcttgc tgaagcttct aatagttgtt
    21361 tcgtttcttt aaccatttct tgaacaagcg gagtagtatc tatcttacta tatgatagcg
    21421 gttttacgcc cgtaagaggt ggagctactt gcaaatcagg cacagtagct atatcttcgt
    21481 ctaaatggcg atatcccttt tcattagcta aggttttaag caaagtcaac tggtgttctg
    21541 tggtagcaat agtagcttct agactgcttt gtttagcttg taaggctgct aaagtttctt
    21601 gtgcatttaa caaagatgag gtagttttag ctaaatcttg cttagtatta tcaatgcgct
    21661 cacgtatcac ttgaaggcgg ttaggattca atttaaagtc ccttagatat tgcaaatgag
    21721 cttttttagc caccagtgct gtcactctgg ctgcggcttg ctctgctaag acttctgtct
    21781 ggtgcagtgc ggctttcaac gatgctagct tagctaatga ttgatcacga gtagcttcga
    21841 gttgtgcttg ttttgcttta gctgctagta attctgttct caaagaacct ttagtatcat
    21901 ttaattgtct cacttggagg tttaagctgt ctgactgctt aagtgtgctt gctaatttac
    21961 cttgaagttg acttacttta gcttgggctg ccataatgtc agcttcttga tgaatagccg
    22021 acaaacgatt ttctaatgag cttacttttc ctttgatcgc tgcaatagta tcagatacag
    22081 tgcctactct ttgggcataa tcttttgtac ttccaacggc ttttataggg gtcttattaa
    22141 agcgttgatg gttagcaatg ttagactctg gaaacattac aaagtgttca ttcaaagatc
    22201 ctacattgct ggttgaaaat ccaaggtaaa caggcgcatt agggttacgt ttatctacac
    22261 gtaaaaagtt aatagcatgg ccgtatgtat ttccgtgtaa atgatctgta aagagcatat
    22321 acttgatact gtcataaata ccacgtttaa taccattcac agtatgcaca tcgttaaaag
    22381 caccgatatt ctcgtacatg ttatcatcat ttcgaatgag ccctgacgct ccggcagagt
    22441 cttcaataat agttttatca tgaggcccaa caccataatg ccctgatacc cctggctgtc
    22501 cgtagacaaa tgatggtctt gtattaccat gagttttctt atagctggta ctaagtaatc
    22561 ttgcaaattc ttgtgatcct gctgtaacag taactggtgg tagacctaat tgtcttctta
    22621 cactattaat catgtgagct gcaaactgcg ctagctcatt ttgcacttct ggtgtcaaat
    22681 tatcgggatc aacaaagcga ttacgatctg ctggaatatc ttggtattga tttaattgat
    22741 tacctggact agctttggca ataatttgat ctgcatgctc tttgtaataa ttattgtaac
    22801 tagctgatcc aatataacca ctagcttcta attttttaag ttcttcaaga ggatagcctt
    22861 gcggtacttt catggtatta ttacccacaa tgctatcttg agtagacgga gctgaggatt
    22921 taagacgact aagttctgcc tctttttctg ctagagcagc tttctgagct gccaactctt
    22981 cagtcaattg ctttttaact ttagcttttt gattttctaa gtcagcttta gccttctcca
    23041 attctgagct taatgctttt gtattatcat tagccgtttg agctgcttta gtgatagcat
    23101 caggattgct aatcatagca ttgagcttag caatattttg ttcagacgtt ttgacttgtt
    23161 ccactaaatc ttgagctcga gtagtttctg ctgaaatgct agctttttgt tctgacaatg
    23221 cagtctcttt tgaatgttga tctgcttgag cattatgaag ctctgtttca gtagctgtta
    23281 actctctttg atgttcggct ccttgggcta atagcgtctc ctcactactt gcaagagtat
    23341 tagtgtaaat ttcttgtgca gaggttaaag ctttttgttc attatcttgc tgctctttta
    23401 agtggttgat ttcagcagta gtttttgtca gagcggtagc aagctctgtc agttctgctt
    23461 tttgttgact gagagttttt tcaactgcat caatagttgc ctttgcctct tgaattgttt
    23521 ctggttttgg taaactatcg tcgtgagtat tactcgcctt cgtttctcct gaggctctat
    23581 catctgcttt gacttggtga gatacgccta cactggcact caataaagca attgttgagg
    23641 ttaaagcaat tttctgctta acttggtttg gcttcgtttg ttctaagtcc attctctctc
    23701 ctttttccat ttatcgaaaa tattaccaac ttctacaaca acattgttgt ttttgacatc
    23761 aatctctgaa actttcagca atgatttgaa ggtcatttgc tcacgctctg attgagcgtt
    23821 ttctgcaaac acagcaacac caactaaagt gctgtcaaat tctgtcaaga gactgatcat
    23881 tcctgtaatc gtccccccgc ccttcaagaa atcatctaca atcaatacac gactattggg
    23941 tttcaaacta cgctttgaca gaaacatctt ttcaatacga tcactagaag cactcgcata
    24001 attgacagac actgtcgatc cttctgttat ttttaaatca cgtctaacaa tgacaaaagg
    24061 aacacttaaa atattagcca ctgcatttgc taaaggaact cctttggttg caactgtcat
    24121 cacagcgtca atcttttctc ctttaaaggc attggcaata atacgaccaa tattttgtaa
    24181 aattttaggt gtactcagca agtctgacaa atagatatag cctccaggta agatgcgatc
    24241 actctctgat aacctttgac acaggtcttc aacaatggta cgcgcttctg tttctgaaat
    24301 actgggggta aaaattacgc ctccacttgc tcctgtaagt gtatcgatat caccaatgtt
    24361 agcttcttca aaagctttct tgataatagc gatatcttct gagatagaag attttgcggc
    24421 ctcatattta gttgcaaagg tgtttaaact agttaattta tacggattgt taatcaaata
    24481 atttgaaatg acaaccatac gttcacttcg tcttaatttc atagtttccc catttttatg
    24541 tactttttgc tattatacca taaagttaat aaaaaacgaa cattcgatta ggaaaatatt
    24601 ggtttttttg ttcttattaa tatcatgcaa gaattcaatc taagataaac taatcaacat
    24661 tcctactgaa aggacattct acttaataac cataacaaga gccaaaaaca cttatgaaac
    24721 catcataagt gttaagcaca tcaaaaatca tcacaaaagc aaagtaacta ttacttgaga
    24781 aacactgatc aatagtttgg cttgtaaaaa gaccgattat ccatggcaaa aatccgattg
    24841 gtcatctcgc cctcgctaac acggctaaga gctgttgtca tcatcatcat attagcatca
    24901 atattgtcaa tcatatgaat aatttcagct tccatgatgc gtggacgtac cggactaccg
    24961 tattctaatt gcccgtgatg gcttaaaatc acgtgcctaa ggacaatgac ttcttctttg
    25021 gtatcatcga tttgtagttc tgaaattact tttgtaattt cttcgttaat gagagaaata
    25081 tgcccaatca agttaccacg aacggtgtat tctgtattat ctggtcctgt taattctatg
    25141 actttagcta agtcatgtaa cataatacct gcaaacagta gactcttatt taagtcaggg
    25201 tagatatctc caatgctatc tgctagtctg accatcgtag cagtatggta ggcgaggcct
    25261 gactcaaaag catggtggtt tgttttagct gcaggataag tataaaattc tttatcatac
    25321 ttacgataaa gagcccttac aattcgttgc cacgttgcat tttcaatttt aaagagcatc
    25381 tgttccaaat agtcacgtac ttctgtcaca ctgacaggtg ccttttcttt gaagtccttt
    25441 ggatcattgg gctcacctgg gcgaacattt cgcaaggtga tttgattaac ctgaggggta
    25501 ccattataca cctcgcgtcg ccctttcata aacacgactt taccagcagt aaattcttca
    25561 acgttataag gttgggcatc ccacagattt cctgaaatct cgccagtgtc atcctgaaag
    25621 gtaaggctaa taaaatcttt accagctctt gtcttacgaa cctctgccga cttaatgagg
    25681 tagaaccctt caaaaagctg gtcttttttc atttgattaa ttttcattat tttcctcttc
    25741 taataagggc atgttcaaga gagattttgt tgtttggtct tgataagttt caacggtatt
    25801 caaggctcga acaatggcat ttgtccttgt tgaaatgagc tgatccagcg tattattagc
    25861 tgtattcatt tgcttttgag ccttggcaag caggccacca aatttatcga attctaactt
    25921 gacattgccc aaaattttac tgatgtcatc agcatttttt tggatattaa gggtcttgaa
    25981 accaacagat aaggaattga gcaaagcaga cagggtcgaa ggacctgcaa ccacaatatt
    26041 ttcttcccga cgaaggctat caaagaaagc cgcatttctg accacttctg aataaagacc
    26101 ttctgttggt aagaacataa ctccgaaatt ggtcgtctct ggggggttca agtacttttt
    26161 atgaatgtct ttggcaaagc gtttgatagc tgccagaagt gcttttcggc tagcctcgat
    26221 ggccagttta tcaccaactt cgtaagcatc ttctaatcgg taataatctt caagagggaa
    26281 ttttgagtca atcggtaggt aaatataacc gccttgacca tttcctggga gcttaatcgc
    26341 atattctacg cgttcactag aaccactaac cgttacaaat tctctttcgt actggcttga
    26401 tgtcatgata tcctcaatga tttggcctag ttgaagttcg cctaaaatgc ctcgtgtttt
    26461 ggtattggac aaaaccttat ttaaagtacc cacatcttga gccacgctac gcatttctcc
    26521 caagccttta ttgacacttt ctagttgctt ggatacagaa tcgaaagagg cgtgcagacg
    26581 attttttaag gtttcttcca atttttcttc aacgatctgg cgcatttcct ccaaacgttt
    26641 ttcgttagat tcttgcatat ttttgagcga ttggttgacc tgctggttaa tttcttctaa
    26701 gcgtttgtca gaccggtccc tactatcaga caaactacgg tgcaagacgt cacgaatatc
    26761 tgttaattgt tggtaaaggt ctgcttgttg tcggttcatc agctgtgtta gctctaacaa
    26821 ttgttgcttg ttagctgtat ccaactggta ggttatttgg tcagacaaat tatccgcgtt
    26881 gccttctagg gtttgggcaa gctgatgttg aaggccgttg actttgaaca acagataagc
    26941 ccctaaacct aagagaacca agaccaaaag gaacaagata aggtccatac taactccaat
    27001 ctttactttg aataataatc aagtagccac ttggcaaact aactgtaata ggttgatgga
    27061 taaaggcatt actggaatag attttctttt tgaaaaaatt atcttgcgtc aactcaaatt
    27121 tagcaccagt aatggtcaag tcagcttctc cttctgccat aaatgccaca taggtcatcc
    27181 cttcttcttg atggataagg tgctgacctg ccgggcggta ggtaatcata ttttgttggt
    27241 cacgcaaggc gatttgtgcc ataaagggag caataccagg gtcgctaggc aagaaaatat
    27301 tggataagag gtggtccatt cgacccccaa aagccccaaa aatggtcact tccgcctcag
    27361 gaaaacgagc aaagacctct ttaagggcta attccgtatc cgtatcattt ttttctggat
    27421 gagcagtaat aaaaagctct gccttctctt ttatatccgt aaacgctttt tgggaaaccg
    27481 aatcaaaatc accaacagcc atattcaaag gaagcccatt ttctaataaa aataggctcc
    27541 ctctatcaat accgacaaaa taatcaaaat cacggctgat ataagagaga tctcctcccg
    27601 caaaaagagc aactttagac attcaaggcc gtccttaagg tttggacttg gctcactagg
    27661 tcactggcct tgaaaaggta agaacctgcc acaaagacat tggcccctgc ttcataacaa
    27721 gcacgaatgg tcttattgtc tactccgcca tcaacctcaa tgtcaaagga caatcctttt
    27781 tcatctcgcc atttggctac ggtagccact ttttctaaac attctgggat aaaggcctga
    27841 cccccaaaac ctgggttgac tgtcataatg aggacttggt caactaagtc tagcaaaggt
    27901 tctagggctg ttgcaggagt tcctggatta atcactaccc ctgctttcat gccagctgcc
    27961 ttgatttttt gaagggctcc atgaatatga cgagtacttt ctgtgtgaat ggtcatgata
    28021 tcaacaccag cttgagcaaa agcctcaaca tagcgttcag gatcaaccac cattagatgg
    28081 caatcaaaga ccaatttact gtgctttctc atacttgcca caacatctgc accaaaactg
    28141 atgttaggaa caaattgacc atccataata tcaatgtgaa cgtattcggc atctgtttct
    28201 tcaatacgag ctagctcaga agcaaaatta gcataatcag ctgctagaat agatggggca
    28261 atttttagag ttgacatgga gtagacctac tttcttttga taactttttt atatgtttca
    28321 cgacggtttt caatttcact gagaaattgc aggtaatgct cataacgaac tggccacaac
    28381 tctcccgttt caagcgctgc cttgacagca cacttgggtt cgtgggtatg ggtacaggat
    28441 ctaaacttac actcatggct cagccggcgc agctctggaa aagcctcgtt caaatcttca
    28501 gcattagcaa tatcatagtc taatgatgaa aaacctggcg tatccgcgat ttttccgcca
    28561 tgggtattgt aaaaactcac agctcgggtg gtgtgacgac cacgccctag actatctgag
    28621 atttctcctg tttcaagagc caattcgggg gcgattcggt tgagaagggt tgatttccca
    28681 acacctgttt gtcccataaa gacggtaatt ttatcagcta gcaaaggcaa caattcctca
    28741 agactggtca caaaatcgta accgattgcc tgatactgtc gaccaatagc cttaatctcc
    28801 tcgggactat ctaataagtc catcttagag atataaacca ctggatgaat ggctttgtgt
    28861 tcaagcaaga tgagaaagcg gtctagaaga ttgctgttaa attctggttc tttagcagac
    28921 ataataacca ctgcttggtc aatattgacg ataggaggtc ttaccaaact gtttttacga
    28981 ggatgaatcg ctaaaatata accttcagag ttgtcctctg ctgagaaatc cacgatatct
    29041 ccaacataag gtgtctcacc gcgcttccta aaattaccac gcgctcgcgt ctgatatacc
    29101 tgtccttctg actccacgta ataaaaacca gccagagatt taatgatttt accttgcaac
    29161 tgtgctcctt tgccctacta taataactct attatatcag aaaaccgctc ccaaatcagc
    29221 atttgactct aagtttcact cgccttaaaa aactgtcaag attctctaga ccactggcta
    29281 tcatttaggt cactgctttt taaaaataga atattttatc aactaaaaat cagatcactg
    29341 atgatttttg aggtaggaaa cgatatgaat tttaagaaga cctttgctat ttacgaaaaa
    29401 gagtctaacc gtaccgctat agtcacgctc ttgttaattg cccctttttt ccggggtatt
    29461 aaaaaaacta gctctgcact gcgatacctt aacggccagc ttcaataaga aaaatccccc
    29521 tgaactgaac atttctgttt tgtctacaag ggaatttttt tattgtcacc gggagaaagc
    29581 ttttataatc caacttcttt taaagcatca gctaatttgc caaaatcttg aatcgacaag
    29641 gcctcaccac gaatagaagg cttgatatct gctagtgcta gacctttttc aagtttagtc
    29701 ttgatgtctt cagacttccc aaaatggcta gtcaagttat tccacagggt cttgcgacga
    29761 tggacaaaac tgagacgaga tactctgaaa aagaaatctt cgtccttaac ctcaatcaaa
    29821 ggctggtcgc gacgcaccat tttgaggata gcactatcga catttggtgc aggtacaaag
    29881 acggtgcgcg gcacaatgaa ggcaaccttg gcagtcatgt aatactgcac cgcaatggac
    29941 aaggaaccat aagctttagt gtttggctca gccgagatac gatctgccac ttcacgctgc
    30001 atcatgacta caaactcttg gaatggaatt ttgctctcaa tcaagtgcat gagaataggc
    30061 gttgtgatgt agtaaggtag attagccacc accttaatgg gcaaatcagg atttttaaac
    30121 tgcttgattt gggtctgcaa atcagctttt aaaatatctt gattgaccac ttgcacatta
    30181 tcaaaatcgc gcaaggtatc tgccaaaatc ggcaccaagc ggtcatcaat ctcaaaagcc
    30241 atcacttcag cagcattttc tgccaaaaat tccgtcaaag ccccaattcc aggaccaatc
    30301 tcgataacat tgacattctg atcaatctca gccgtgtcaa cgattttctg taaaatattg
    30361 gtatcggtca aaaagttctg accaaaagat ttcttaaagg taaatccgtg acgatcaagg
    30421 acagccttgg tcacgctata atctgcaatt ctcatatatt ctcttctttt tatgatcact
    30481 ttctttttgg catttgaacc actagcctaa acttttttgc caagatacgc cattcagtta
    30541 atggggctgt tatattttat tgtactcttt actcctcata tgtctccatc acttcttcca
    30601 cttctgctag ggtaatgcca aataattcga ggcgcttgag cagttgtttg ccgttggcat
    30661 agccgatgcg gagcttttcg cccaagtatt ccctgcgttt acggctatct gacgccatta
    30721 aaagccctag acgaatcagg tctgtttgac gaatgtcaaa ataagactca tcatcatatt
    30781 gctgagtgac atgagcaagt gccttttgga ggtcctcaaa attggcatgt tcaaccccta
    30841 aggaacggcc cttactctta gaactcggaa ccgcctcgtt tcggtttaaa aaggcgtgac
    30901 gagctgttgg cacagctgcc ataatgagct tacgaatgcg ctcaccatta taatctgggt
    30961 ctgtcaaaac aatgacacca cgcaagtcat ttaggcggtt aatccgttct aaatcttctt
    31021 cagtgatagc agagcctctg gtctcatagg tatccacctc gtaaaaacgg cgaaggttag
    31081 ccgtgtcgtc cttgccttct acaacaagaa cctcttgaat attaattttt tcagtcaagc
    31141 ttaagtaccc tctttgcatt agcagtcgtt tcttttgcaa cttcttccac ggtcattccc
    31201 cgtagctctg cgattttatc aaccacataa cgggtataag ctgtatgatt ttgtttgcca
    31261 cgttttggaa ctggtgtaag ataaggggca tctgtttcca ccaaaatctt atccaaaggc
    31321 aagtgctgcg ctgcctcttg aatatcaagg gcctttttga aagtgaccac acctgaaaaa
    31381 gaaatcatca tgccaagttc aatgaaacgt tcagccatct ctaatgatcc tgagtaagaa
    31441 tgcatgatgc ctccacgagg gccaacacca gctgctttga tgacctcata ggtatcttcc
    31501 aaggcatcgc gggtgtgcac cacaaaaggc aaatcatggt cttttgctaa ttgcatttgg
    31561 cgcttaaaaa cctctatttg cacctctttg gggtcctcca tccaataata gtctaagcca
    31621 atttcaccta aggcaatgac tttaggatgt gataattgag agacgataga ctcctcaact
    31681 gcttcagaat aagatcctgc ttctgtcggg tgccatccaa tagtagcata cacgttagga
    31741 tactggtctg cgagagcaag tgctccacta atagtggcct ggtcaaagcc aaccacatta
    31801 tggtaggcca cgcccatttc ttgagccaaa gtcaattctt cagtttcgtg tccttgaaat
    31861 tctgctacat tcaggtgcgt atgggtatca aaaatagtta gtttttctac tttatttgtc
    31921 atgatgttat tataacataa agatcttaac cacatcagaa aacttggtga gaacttctgc
    31981 cgtttaggtt gatcgtaaaa ccctttgcta gctgacactt gtctattttc tacttttttg
    32041 acaaatgacc tttaatagtc ggctcctaca taagccctca aaaatactac aacctactca
    32101 aataaagtgg gttgaacaaa tctgtatcac aaaaagggtc gctaccttct gttagcgatc
    32161 tatgctatac tagtagatag ttaaactgta aggagtatgc tttgctatgc ctaaaaacca
    32221 ccgcctaatt accaaaatcg aagcatcatt ggaacatatg accagtttag aaaaagggat
    32281 tgctcatttt tttattacaa ccgatctgac acctcaagag ttgaccgcat ccgagatagt
    32341 taagcgacta cacatctctc aagccgcctt gactcgattt gcaaaaaagt gtggttttac
    32401 tggttatcgt gcttttgcct ttgattacct tcacagtctt caagaatcac aagagacttt
    32461 ccaatctatt cacttagaat tgacaaagcg cgtgctgatg gactacgatg ctcttattaa
    32521 taaaacctat gagctcgtta atgaagaaaa attactgaac ttagccaagc tgatcgatgc
    32581 ttctgagcga gtctatttct ttggcaaagg atcttctgga ctagtagcaa gagaaatgaa
    32641 gctacgcttt atgcgacttg gtttaatctg tgatgcttat tcagacactg atggttttac
    32701 ttgggcaaat agcctcgtca atgaaaattg ccttgttttt ggtttttctt tatctggcaa
    32761 aacaaactct gtcatcacag cacttcatca agctagtcag cgaggggcca aaactgtcct
    32821 cttaacaaca gataatcaaa ccgaatttga cgactcctta gatattattc ccgtatcatc
    32881 aacccaccaa ctacattatg ggaatcgtgt gtcaccacaa tttcctcttc ttattatgat
    32941 ggacattatt tatgcttacg ttttagcgat tgacaaaccg cacaaagaaa aaatcttcaa
    33001 aaacactatt attgacaaag aaaataacgg cctttagact acaatagcaa aaagggcgtt
    33061 gttttctttt taaagggtcg tcattcacct cccccagtat acttaaacaa gaactcttca
    33121 cgtcatatag actcacagcc actaagatta gctactcgct aaattatttt cgattttctc
    33181 aagagttata aatgaacagg atcgctcatt cttttgttta aaatggtagt aagctcctaa
    33241 tataccagca ttatttccat gactagcaaa cttcagctga gttttcttgg caagactaga
    33301 aaccaagtag ctatcaagag ctgtctttaa tttatcagct aaatagtctt tttgcaccat
    33361 gattccgcca ccaagtacca ccacatttgg gttaacaacg tagcagatat tagcaatacc
    33421 ttgtcctaag taatccacct gcttactaat ggctgctata caaatcgcat cacccgcttt
    33481 agcctgctca aaaatacgac gaccatccca ttggctaatg tcatccccat aagctaaggc
    33541 cacctcttga acaagagctg tggtagatgc cagatcctga aactgaccat ctgacaaatg
    33601 aaggtaacca acttcgcaag ctgaatgact actaccatga aaaacttggg aattaaacaa
    33661 taaacagcca ccgattcccg tcccaattgt caagcaaaga gccacaggat aatccttggc
    33721 actgccagaa atagcttcgg ctagaccagc acagttaaca tcgttttcca cttcacacgg
    33781 taacccgaaa gtctcttcaa tctctttttt aaactgagtt ccagcatagt taggaatctg
    33841 agggccggca taaaagattt ctcccttatc aggattaacc attcctgcag aagaaatggc
    33901 cactccagcc agatccattt ggtcttgata ggtctttacc aagcccttga ccttttccaa
    33961 aatagaggga ccacctttat aagcctcagt ggccatttcc tctttttcca acaggtctcc
    34021 tgtttcagaa atcaagccat acttgatagc agtaccacca atatcaattg ctaaataatg
    34081 cttcatttgt tatcccctcg catcttatta aaaggtttcc ttagcctgat taatcagagc
    34141 agcagcccgt tggcaaataa ccctatcttc ctcgaccaac tcagctaaag gtgatcgaac
    34201 agaaccaata tcaagaccct cattaatacg aagtacttcc ttaataaccc catacatatt
    34261 gccgtgagca gaaacaagga caccgatagt ctcattaata gtatattgaa gggtcttggc
    34321 cttttctaaa tccttgtcaa ctataagttg attcagcctt aaaaataatt ctggcatagc
    34381 cccgtaggtg ccaccaatgc ctgcagcagc acccatcaag cgccctccta gaaattgttc
    34441 atctgggcca ttaaaaacaa tatgatcgtc tccgccaatc gcacagaagg tttgaatatc
    34501 ctgcactggc atggatgaat ttttaacgcc aatcacgcgc ttattagcca acatagtctt
    34561 ataaaggctt ggggtcaagg caacccctgc cagttgagga atattataga tgataaaatc
    34621 tgtgtgagga gcagccgaag aaatcgcatt ccaataatca gcaactgcat attctggtaa
    34681 ccggaaataa ataggcggaa tagctgcaat ggcatccacg cccaaacgtt ctgaatgagc
    34741 tgccaattca atactatctt tagtgttgtt gcaggcaacg tgattaataa tcgtcagctt
    34801 gcccttagcg actgccatga cattttctaa caccaattga cggtcaaaaa cgctctggta
    34861 aatacactct ccagaagagc cattaatgta aagcccctga acccctttgt caatatagta
    34921 ctgggtcaag gcacgcacac gctcagggct aatagctcct tggtcatcgt aacaagcata
    34981 aaaggcagga ataatgcctt ggtatttcgt aagatctgtc atagtaatgt cctttattca
    35041 atgtcattat taagtgggaa tcgcctaaga agggattcca tgataatcaa gtagaggtaa
    35101 gttaggctac tgatgcccat agtggccagt agagacaagc cacaaaataa ggttaacagg
    35161 gttaacggca aggtaaaaac caaaaggcca atcaccacta gaaaagcaaa cgtccatggg
    35221 aataaaattc ctgccagcag taaacttcgc ttaaagagta ttaaaagagg aagctctttt
    35281 ctgacggcct gaggataagc gtacaaaaag agtataacta ccaaaaataa aacagcaatg
    35341 caaagtactt taaacccttg aaaaactagg cctgattggt ttcgaattaa gaaaagatct
    35401 aagacacaaa tactcattat caaaagctca ataagaccta ggcgcatccc acttttaaaa
    35461 taatgtttaa aatgagagct ataagtagta acaagctgac taacttgacc ttctcgccaa
    35521 tccaacaaac tcgcatacaa agccatttta gcaaccccaa tcgttagaag gggaaggcag
    35581 gacaagacaa ataagagatt aaacacgagc aaatcaaaca gtgctgcgct agccctcatc
    35641 catttactat caagcttgaa gagagagtgt aaaagtccct gttttttcga tgtcaaatca
    35701 caacttcctt tctagaaata cgcttacaaa caaaagctaa ttcccctctt aaacgtttaa
    35761 cacatgactt gcttcccatc tgatttatct atgtatgcac ctaaattaat aagcaaccta
    35821 taaattaagc ttagcgacac gctttattta gtctaacctt tcacagcacc catagtaatg
    35881 ccttgggtaa atgatttttg gaagacaaga aataccgtca caataggcac tgcagccatg
    35941 gcagcccctg ccataatcaa gccataatta gtagccattt cagcttgcat agtggcaacc
    36001 ccaagtgaaa tcgttaaatt ttcccgagag gttaacatca ccaactgcat aaaataatca
    36061 ttccaagtat tgataaaggt aaaaattgct agcgctgcaa agcctggttt gacaataggg
    36121 aaagccacat tgaaaaaggt acgaatttcg ccacatccat caatcttggc ggattccaat
    36181 aactcggttg gaatattttc tgagaactgt ttcataagga aaacaccaaa tggccagccc
    36241 acaagaggca aaataacagc cgccaaagtg tcatggattc ccataaaatt aacaatccgc
    36301 acaagaggca ctagaacaac ctgttttggc aaggccatag cagcaataaa aatcgaaaac
    36361 aaaagccgct gtccataaaa ccgctttttg gccaaagcat agccagccaa agaggaagtg
    36421 ccacaaacca agaacatggt cgccaccgaa ataaagacac tattccacaa ccattttaag
    36481 gctggatttt gcactaccaa ggccttaaaa ttttcaatag taggtgcctt tggccaccat
    36541 tgcggtggaa tcataatggt atcggcttga gccttaaatg ctcctgtcat aatccaataa
    36601 aatgggaaaa taaacaaaat ggtcaagatg catagaataa cagtagtcag aacatccgat
    36661 gcggttagtt tctttttcgt catcttaata tcctcctaat attccacatc attacctaaa
    36721 attttaaatt gagcaaagct gatgattgca atcatgactg ccaagaacac acccattgtg
    36781 ttggcatagc cgtattcaga gagcttaaag gctttttcat acaaatagta catgagggta
    36841 ctagttgaat aatttggccc tccagacgtc aagagttgaa tcaaagcaaa acattggaag
    36901 gaattaatgg ttgttatgac agcaatatat aaggttgttg gcaggagact tggccacttg
    36961 atattccaaa acacctgaaa ttctgtggcg ccgtctacac gcgcagcttc catcaaagaa
    37021 ttatcaatat ttcccatagc agcaatatat agaataatag gctgcccaac agatgtggtt
    37081 aataaaatag caataatagc taacaaagcc cagtgcttat ctcccagcca actaatgttt
    37141 tgttcaatca catgagcata ttttaagaca taattcaaaa tccctgacat cggatcataa
    37201 atccatttcc aaaccaccgt tacggcaaca cttccggtaa caacaggtag aaagaaaact
    37261 gcccgataaa acgaacgcgc caccacattt ttgtcataag tcttagccgc cacaaagagg
    37321 gaaaagaaaa ctacaacagg taccgaacca ataacgataa tcaacgtatt gataagagat
    37381 ttcataaaga taggatcttg aaacatccta gcataattgg caaaaccaac aaaggtaaaa
    37441 tccgtcatgg aataattgaa aaaactcgtc acaaagccca taatcatcgg tatcaagaca
    37501 aaaatcacaa agaaaaccaa gaccggagct aagaaagcgt atgagatgag cgtctctcgc
    37561 atttttaatt tattgacgtt cacttgaaat acctcttttt tctgttcaac ttttctaaaa
    37621 agaaaagctt ctttccagtg accatttgac atgtgcattg aaaagaagcc acttgttctg
    37681 aacacttatt gtgttttttt gattgtcttg ttcgcttttt cagtgaaggc tttcaaagca
    37741 tcttctggct tttcatcacc attagagacg gcttgaacca ttgggaacca aagagttctc
    37801 atttcagcaa acccatcaat cgtgttgtag tatggtgagt agaattttgt ccattcagca
    37861 attttttcca ttcgtttgtc tttgtaaaga tccccataag aagttcttac agggaaagca
    37921 cctgtacgaa caacattttt aggtccccat tctttatcat cagcgataaa ctggataaat
    37981 gtcttagagg cagcgacttt ttgttcatct ttgttattaa agaccgcaaa accatttacg
    38041 aggtattcta gttctggttt gccatcatct gatgggaatg ggatttcaag gtaatccact
    38101 ttactagctt ctaacaattt agcttggatg ccgggttgtg caggcgccca aagaatggta
    38161 aaggaagttt ggccattcgc aaagttttga atatcagctg aaccgtcgta ttgagagcca
    38221 ttcatcatta aaccatcttt aatccaattg gaaattttag tcatggcttt aatagagtta
    38281 gcatcatctg tggtgtattt ggttactttg tcatcggtaa tatgactact ataaaggtta
    38341 gcaaagaagg cacgtggtcc ttggtcacca ccttgaccat tagcaaagaa agaacctggg
    38401 ttatatcctt tgtccttcaa tgctttcaag actttttcaa aatcatctgt tgtccaaccc
    38461 tctttcacaa ggtcaaggac accagcatct ttgagcattt ttttattcaa cgccatgtag
    38521 aatggagcag agctgatagg atacatgtaa gctgtatctc ctgcttttga ggcttgaatc
    38581 aatttgtcat tgttaacatc tttggtaaac tcttctgtga acaagtcatt caagtcagcc
    38641 aatttcccat ttttaccata ttgaatgata cgacctggag catcaaagag gacatcagga
    38701 gctgttccag cttcaatagc agttgtgatt ttctcaggac cagatgtaaa atcaatggtt
    38761 tccaatttta ccttgatttc tggattagct ttctcaaagg cagcaatcaa tttcttctca
    38821 taggttccca caccatcttc agctttttct tgcgtgaaga ccgggaaagc ccaccatgtg
    38881 atttctgtct tagcagtatc agatttactt gcaccagcct ctttctggct ctttccgcca
    38941 caagctgcta gtcctaaaac agatgcacca agcatcacta atgaagctaa cttcttcatg
    39001 ttcatcgtaa aatctccttt ttttgatgtg tgtttctatt ttgacaacca ctattaggat
    39061 ttgagcgctt cgataaaacg ctctgcaatt tccttaggcc ttgtaatggc ccctccaaca
    39121 acaatacctg ccacacctaa gtcattaatt ttcttggctt cttctgggga atgaatcttt
    39181 ccttcggcaa tgacagcaat gcctgctttg caaagagctt ctatcaatgc cacatcagga
    39241 cctgcttcct gacggctata cggggtgtag cctgacaagg tggttccaac aaaatcaatg
    39301 ccagcctgat gggccactag tccttcatca aaggtactaa tatctgccat caaaagctga
    39361 ttggggtact tttccttaac ttgtcgaata aagctagcaa tatccaagcc atcatgtcgg
    39421 tcacgcttgg tacaatccat agcaatcact gcaatattta aggcagctaa ttgatccact
    39481 tcggccatcg ttgccgtaat aaaaggctct tgcggcgggt aatctttttt gatgataccg
    39541 ataattggta ggtctgttat ggcttgaatt tctttaatgt ctctaaccga attagctctg
    39601 atgccgacag caccagcttc ttgagcagct tttgccagca gtggcataat acccccagtc
    39661 tctgaataga gaggctcacc tggcaaagcc tgacaagaaa cgataatccc accctttaac
    39721 tgctccatga gcttttcttt ggttggttta tcaggcatag tttctactcc ttgtgtttct
    39781 tagttttaat aaaaataacg ttcacaaagt tattataaca aaaaataaag cgctttcaat
    39841 agcaatgaga cttttagaat ctactttcat tttttatatt attttctatt atttggaatg
    39901 ctctttcata caacaaataa aaaggtaagg agttgacacc atacttatac attgcaaatt
    39961 cccgattaga aaacgttaaa aaaccaagag cctcgagcac tcttggttta ctttagttgt
    40021 attttttgca attaagctga taatacttta cgtcctttac gacgacgtgc agcaagcacg
    40081 cgacgtccgt ttttagttga catacggtga cggaatccgt gtttacgttg acgacggatt
    40141 ttacttggtt gataagtacg tttcacagtg aatacctcct catagatttt gtattcgttt
    40201 agccggctat ttgtgatatc agttactaaa catactataa tattctatct taaagagggt
    40261 ctactgtcaa gatttatttt cgtttttcaa cagtttctct ctcatttaag aggccgctca
    40321 tttcataaag tgtctcttct ttgacactgt tcctttgcct taccgttgaa accttatcaa
    40381 tagcaacaat aatcaatgag atcagtaaaa caaacggtta agctggccat acaaaaaatc
    40441 ttcgatagct aaactaacta ccaaagattc tttttaggat ctaacgttga agactgacta
    40501 ccacatagcg gttagggtca ttgccttcag aataactatc aaccccttca atggatgaaa
    40561 cggttttatg aacgatttta cgctcactgt tactcatggg atccatggtg taatcttgac
    40621 cagattccaa gacgcgtttg gcaacttttt gcgtaaagtc aatcaaggtt tctgttcgat
    40681 gttccacata atcatggaca ttcaaggata ctgaaaaatt ttttgaatag cggtcgtgca
    40741 agaaattttg agctaacaac tgcaaggatt tcaaaacctt accatggtaa ccaatcacac
    40801 gtcccgcctc tggcgtttca atctgcaaat tgatttggcg acgattgttg ctggtttcaa
    40861 cggtggcttc gatatccatt tcatagatga ttttagtcac ataatcggac acttcctgag
    40921 cagctttttc aatatctttg ctgaaaccat cattaccagg atcttggggc acttctgatt
    40981 cctcgactgg gattgacggt tgttgtgctt ttgtttcagt gactgtctca gcaagattag
    41041 aaagggtttg cgctggacta tcttcagaca tgagaggaac cactttggta tcttctgctt
    41101 ctaacttttg agtggctttt atttcttcag gttctacatc agcagaattg accgcgggag
    41161 catttttttg attaatatcc tctggaacac ctcgagtggc ttttttatca gccttataaa
    41221 ccgtcttgtc gctgatacct tcgatatcaa cttgggctgg ctttttaccg aacccgagga
    41281 aacctttttt ctcttttgaa atgactttga tatgcgcttt aaggcgtgat aaccctaact
    41341 cttgaagtcc tgtttcgata gcttcttcga ctgtttttcc tgtaaataat accataacct
    41401 aaactcctat tttctcttca ttgctttttt acgagcacga cgttcacgaa gacggcgttc
    41461 tttttcttca ttggcaagac gctgtctttc ggcaataatc ttaaaaggat tgtttaatag
    41521 cagtagttgt accacttgaa aggcgtttga gaccgtccaa tagagcacta ctccactagc
    41581 caagttaaag cccatgaaaa agatcattag cggcatcaca taaatcataa cagtcatcat
    41641 gacatttttt tctttagccg ctagattggt caaccaagtg gacaagaaag tgaagacagc
    41701 tgccaaaact ggtaaaaggt acaaatgatc atgttgtgcc aattccaccc acaagaaagt
    41761 ccctgttttt aagaaagata cccgtgtcaa ggcttggaat agggcaatca taactggcat
    41821 ctgaattaag aggggtaaga ggctagcata agggttaacc ccatattttt tgtaaagggc
    41881 ttgactttct tcagccaact tcatccgcgt ttgtgtgtct ttaccagcgt atttcttttg
    41941 caattctcta agctcaggtt ggatgtcttg catcttctgg cttgatttga tttgcatatt
    42001 aaacaaaggc atgagcatga gacggatagt aagggtaaaa agaataatgc caacaccaat
    42061 tgaaccatca aaggaaagcc attgaattgc tctggcaaat aagtaaacca actggtccca
    42121 accactagat gattgtgccg ttacctcacc acgaccacag gccactaata atagaactaa
    42181 ggggactatt cttgcaattt taatgttttt cttcactctc aaaacctttc tcaagcaatt
    42241 gtgctaactt taaaacatga tgtaaatttt gttgaagctc ttgatactcc aaagactcga
    42301 cacccttacg ggcaatcacc acgaaatcct ctgacttcag ctgatgccct aatgccatga
    42361 taacatgacg tatctttcgt ttgactgcat ttctggtgac tgcatttcct atttttttac
    42421 cgacagaaat acccacacgg aagtggtctt ggcctctatt taaatgataa atgacaaatt
    42481 ttcgatttgc tgtacttttt ccatccttaa atatggcttg gaaatctttc tcacgcttga
    42541 cacgataggt cttcttcaaa atttaactcc aatatctaaa ttattaccat tataccacat
    42601 cccctaaaaa attaaaaagc cctaaccctt tcagattaag cctctttctg tactatttct
    42661 agtttttgtg cttcaactgc ctcttgtcac tccatctttt cgtagtatag ttcttctttc
    42721 gacaaaggaa taaccttcag aaaacaacca taaaaagtca gaatccacaa gacgtcagct
    42781 acttatccct gtatttacct atcaaaaaac ccggcaagcc gggctttgat actgatttta
    42841 caatcagcta atgtgatatc caaacaaaga caactgacat cgtcattttg tctgccgagc
    42901 catcatatca aaaatactat ttgtttatgg agagagagaa aacaatattt tgattgaatt
    42961 ggggattgat tgctcgataa actcatgact tcgtaaatct ttatttacac taattattat
    43021 agcgaaaaat gtttcaataa gagcatcatt tcctgaaatg ttgctttttc gtcctaaaat
    43081 gttattgctc tcttaacttt agcgaagagc ctcccaccgt tcaaacagac atttcatttt
    43141 taatcgtgat accatacaag aatcaccatt ttcgaaataa aggagctgct tactcttatc
    43201 aattcgaaca accttatcta gattcacaag gtaggatcta tggcacaaaa aaagtttcgg
    43261 tgctactgct tgaatctcag atagattacc ataaaactct aatctttctg tctgagtcca
    43321 taaacaaact ttgtgaggag ttgtggctgt agcaaagtat aaaatatcct tatagggcaa
    43381 ttttaatctt gtctgtggag tctcaaataa aaacatgtcc tttgactcac gactagacat
    43441 catatcgtaa gtatatcgga tacattcttc gatttgttct ttaaactgtt tttgaccacc
    43501 tgctttatca ataaaatcta gagcggatac cttatattta aaagaaatag gagcaaattc
    43561 tgaatgagtg gtgacaaaca caataacggc attaggatct ttttgtcgaa tagctgcagc
    43621 taattcaagc ccacaacgag tatattcacc aatttcaata tctaaaaaat acagctgatg
    43681 gtctcctctt tcttggatac tctcaaataa tttttgagga gtcgagaaca cttcaagctg
    43741 attacatggt attctagtct cttttaagat gcctactacg atagattcta tgcgtgtctg
    43801 ctggataaaa tcatcctcaa gaataaaaat gttcatcata ctttatctca tttctaacaa
    43861 ttgtcttaat cgataatggt cacttttagt cgaaagcgtt atttgggggt aactatctaa
    43921 aacagtcaaa aagtgggctg agttctgctg ctgagcatca aagcgtttgg ctatatccac
    43981 acgattggtt tttgtgctat tttcaataat aaataattgc ttgttatctt gtttaaagta
    44041 tgcaatagat aaaaaaggac gtctactgcc tttggctgtc tcaatagcat tgtccactag
    44101 tccagtaaaa agtacaatta agtcgattaa cttaataggt aaatgatcga taacatctgg
    44161 aatctcaata taaagttcaa tacccaaata ctgagcttca agcaatttgg aattcatgat
    44221 actgcgaatc acagcctctt tgatattgtc taaagaagat atttcataat ttgtgcgcat
    44281 catagaagtt gccgattgct gaataaccgt gtcataaact ctagtaatca gatctatatc
    44341 accactatcg atactatctt ttagactaat taagatattt tcagaatcat gtttaactgt
    44401 tctgatttct cggtaaagtt gctcaatcga ttgattgtaa ttttccagat acgcaatacg
    44461 ttcattttgt gcttgtgtta atttttgtga cagctgatct ttagcaaatc gatctaattt
    44521 tacaataacc caaataaaaa tagctaaata aataaatact aaaatagacc ggtactggaa
    44581 atatagtgca agaaatccgc tttgcacagt taccaaaaaa tgggcgaaaa agtagtaaga
    44641 aaacatggca gtattcatcc aaaataccca ctttttcatc ttatcttcac tgataaacct
    44701 tattaagctt aagtcaatac tgaaaatgta gctaaacaga taaaatattg gtaatacaaa
    44761 aagataacat aactctaaaa gcttaaggtt attattaatt tgaccaatgc taaatcctaa
    44821 gacagctggt aaaaagaaag atccgatgac gcgaaacagt aattcgacaa tcaagatagt
    44881 aaagaaacca ttaaacatat gctcaaataa tttctttttc ggagcactta acaaactaac
    44941 aataataaaa aacagttggt caatcaaaat gactttgtca aatatcatat tagcaattac
    45001 aaaactaatg cctataacgc taacccgttt ccagcttagt ttaatagcag aaacctttgc
    45061 aaaaatgacc cagctgttaa taaagatggt agcatagaat aaagccatac tgtatataac
    45121 catcatctat ccacctcctc ctttggcatg gtcaaggttt ggctaaattc cttatcaaaa
    45181 cttttagtcc gcaaggataa ataaggatac tttttgagaa tacgctgcgc attagaaagg
    45241 ccgataccac gttctgaacc ttttgaagaa tagccttctt caaagatctt gttaatgtct
    45301 accttttttt tagtcgtatt tgtcacaaca aacatctgat agtcatctaa caaaaagtaa
    45361 gcaattgaca tatgaggttg ctgtgcttca agagctgcct caatggcgtt atcacaaaaa
    45421 atagacatca acaatagtaa gtccaactca ggaatgtaag tctcttttat attatctggc
    45481 acttccacat tcaaatcaat acctgatttt tccgcactga taattttagc tgacaataag
    45541 ctcttaatcg atgagatatt aattttccta agcttcgaga tattatagtg tttatcatcc
    45601 cagtagtcgt tagcttcatg aaccgtttgg gcataaatat cttgaatctg agtaatggat
    45661 tcactcttaa tggcttgacc taaacgctct atacggctca ggtaatcact ttgaaaagct
    45721 cttacatctc gatagagttt ctcaagatgt ttcccataag tctctaagtt agtcatataa
    45781 gcttgttgtt ctcttctcaa ctcattttta aggtattctt tagaactatg attaaaataa
    45841 gatagaagat aaactaaaag aagtataaac atcaaaaaca ataacttata aggtgtggga
    45901 acaaaaagag aatgatgaaa atgtaaaaag gggtccgtaa atcctaaaat gacaaaaatg
    45961 tccacataat aaaccaaaac aaaaatcagc aatgtttgat aaaaattatg cgatcgtttc
    46021 gaatatccgg attggcatat catcttgtaa tcttttccaa tcatataatt aataatagca
    46081 aaacttggaa aaatcagcag ataagcaagc aagtcaaaga taatatgacc cagataaata
    46141 ccactcgaca aaaaaagata ggggataacg attgtaccca taaaccgaga tagcaaatcc
    46201 accaaaacac taggtgcaac agccaaaaaa agagctttca aagaaaataa ttgcttggtt
    46261 tcttgcctta aaacaactaa aaataataga ggatcaatta gcaatggcga caaatacggg
    46321 aactgattga aaaatagggc taaagccaaa atcgttagtt gtttccaaac tggtaatgtg
    46381 atatcagata gaaaggaaaa aatata
//
LOCUS       DATWVB010000013        41762 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.013, whole genome shotgun sequence.
ACCESSION   DATWVB010000013 DATWVB010000000
VERSION     DATWVB010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41762
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.013"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(75..1379)
                     /locus_tag="VCX65_000780"
     CDS             complement(75..1379)
                     /locus_tag="VCX65_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEP5053254.1"
                     /translation="MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSV
                     SLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIA
                     RFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
                     WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILV
                     MITGLSTVFLGTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLTDSGHQLANSYYAM
                     SNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNV
                     GIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVA
                     VGFVLNIDASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
     gene            complement(1519..4317)
                     /gene="ppc"
                     /locus_tag="VCX65_000781"
     CDS             complement(1519..4317)
                     /gene="ppc"
                     /locus_tag="VCX65_000781"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEP5053255.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQAIIAEEVALLKEMLENITRR
                     MIGDDAFAVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINYQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQIQLTNQPAARMSSSVGLSTSAWSSPASLENPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQESCVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNTIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     GNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEW
                     QLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            4476..6275
                     /gene="pepF"
                     /locus_tag="VCX65_000782"
     CDS             4476..6275
                     /gene="pepF"
                     /locus_tag="VCX65_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEP5053256.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEKALQDIDLFKRN
                     YEGRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRAGDFDMEDFEVDGKTYKNSFVSYENFYQNHENAEIRDKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNDLNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPDGAKEWLDFLKSGGSRTPLDTAMLIG
                     ADIATEKPLRDTIQFLSDTVDQIINYTEEMSHA"
     gene            6268..6747
                     /locus_tag="VCX65_000783"
     CDS             6268..6747
                     /locus_tag="VCX65_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEP5053257.1"
                     /translation="MPNLYDFTVKAQNGNDLSLAAYKKKVVLIVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     ADPLFTWLKEEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(6794..7177)
                     /locus_tag="VCX65_000784"
     CDS             complement(6794..7177)
                     /locus_tag="VCX65_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEP5053258.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQTQTPSVPKADHHVRLVVK
                     EDTNTIDEKVSFGKGDTVLEILKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNGK
                     MADKGADQITVKDGDSIEFYQEVFK"
     gene            complement(7161..7664)
                     /locus_tag="VCX65_000785"
     CDS             complement(7161..7664)
                     /locus_tag="VCX65_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP5053259.1"
                     /translation="MSAKFMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFALYPLSQQFPKYQLGYQ
                     AFLAALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            7989..8837
                     /locus_tag="VCX65_000786"
     CDS             7989..8837
                     /locus_tag="VCX65_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEP5053260.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPSKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDAV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     regulatory      8965..9061
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9106..9669
                     /gene="thiT"
                     /locus_tag="VCX65_000787"
     CDS             9106..9669
                     /gene="thiT"
                     /locus_tag="VCX65_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEP5053261.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMALSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSDSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     gene            9759..10238
                     /locus_tag="VCX65_000788"
     CDS             9759..10238
                     /locus_tag="VCX65_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEP5053262.1"
                     /translation="MAKKTKFKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            10579..11202
                     /locus_tag="VCX65_000789"
     CDS             10579..11202
                     /locus_tag="VCX65_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEP5053263.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATMAAIY
                     PQQMLAFRENLAQFKSDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNTSLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(11310..12212)
                     /locus_tag="VCX65_000790"
     CDS             complement(11310..12212)
                     /locus_tag="VCX65_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEP5053264.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRGRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDVNDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            12386..13879
                     /gene="lysS"
                     /locus_tag="VCX65_000791"
     CDS             12386..13879
                     /gene="lysS"
                     /locus_tag="VCX65_000791"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEP5053265.1"
                     /translation="MSNQHIEELNDQQIVRREKMTALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVD
                     FWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            14015..14155
                     /locus_tag="VCX65_000792"
     CDS             14015..14155
                     /locus_tag="VCX65_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053266.1"
                     /translation="MTKEYISYISAAIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(14252..14464)
                     /locus_tag="VCX65_000793"
     CDS             complement(14252..14464)
                     /locus_tag="VCX65_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEP5053267.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(14681..15967)
                     /locus_tag="VCX65_000794"
     CDS             complement(14681..15967)
                     /locus_tag="VCX65_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEP5053268.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIIICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            complement(16069..16995)
                     /locus_tag="VCX65_000795"
     CDS             complement(16069..16995)
                     /locus_tag="VCX65_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEP5053269.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            17194..17478
                     /locus_tag="VCX65_000796"
     CDS             17194..17478
                     /locus_tag="VCX65_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEP5053270.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLFAKVIKSLLM"
     gene            complement(17639..18067)
                     /locus_tag="VCX65_000797"
     CDS             complement(17639..18067)
                     /locus_tag="VCX65_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEP5053271.1"
                     /translation="MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     LAEVEAKEKQDDVIIDLNEEDIIIDYTEQDEPVSDTLDKH"
     gene            complement(18060..18467)
                     /locus_tag="VCX65_000798"
     CDS             complement(18060..18467)
                     /locus_tag="VCX65_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEP5053272.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            complement(18489..19268)
                     /locus_tag="VCX65_000799"
     CDS             complement(18489..19268)
                     /locus_tag="VCX65_000799"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEP5053273.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            complement(19265..20197)
                     /locus_tag="VCX65_000800"
     CDS             complement(19265..20197)
                     /locus_tag="VCX65_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEP5053274.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            complement(20562..20834)
                     /locus_tag="VCX65_000801"
     CDS             complement(20562..20834)
                     /locus_tag="VCX65_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEP5053275.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            complement(20898..21335)
                     /locus_tag="VCX65_000802"
     CDS             complement(20898..21335)
                     /locus_tag="VCX65_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEP5053276.1"
                     /translation="MTLTNYVQEVSLADFGKPFHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            complement(21322..23454)
                     /locus_tag="VCX65_000803"
     CDS             complement(21322..23454)
                     /locus_tag="VCX65_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEP5053277.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            23688..23843
                     /locus_tag="VCX65_000804"
     CDS             23688..23843
                     /locus_tag="VCX65_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053278.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            23991..24893
                     /locus_tag="VCX65_000805"
     CDS             23991..24893
                     /locus_tag="VCX65_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEP5053279.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKTFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            24893..25708
                     /locus_tag="VCX65_000806"
     CDS             24893..25708
                     /locus_tag="VCX65_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEP5053280.1"
                     /translation="MIRFLILAGYFELTMYLQLSGKLDQYINVRYSYLAYISMVLSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFLDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLTEVHQTKEPNNPYVYRVF"
     gene            complement(25807..27231)
                     /locus_tag="VCX65_000807"
     CDS             complement(25807..27231)
                     /locus_tag="VCX65_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEP5053281.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADTKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMDFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(27250..29112)
                     /locus_tag="VCX65_000808"
     CDS             complement(27250..29112)
                     /locus_tag="VCX65_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEP5053282.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLTLFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFINALIAGAATIVLAFSLTWFMGIDEE
                     SPKQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSE
                     GVVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVSVGDVVK
                     RGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
     gene            complement(29114..29956)
                     /locus_tag="VCX65_000809"
     CDS             complement(29114..29956)
                     /locus_tag="VCX65_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEP5053283.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSE
                     MSYDDDDAELLLVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            30284..31651
                     /locus_tag="VCX65_000810"
     CDS             30284..31651
                     /locus_tag="VCX65_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP5053284.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPFDWLAFIALSISLTSALLA
                     ITSLENGSVNLYYLGLFILSFVLFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGAKLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
                     KKGLA"
     gene            complement(31705..33255)
                     /gene="ftsY"
                     /locus_tag="VCX65_000811"
     CDS             complement(31705..33255)
                     /gene="ftsY"
                     /locus_tag="VCX65_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEP5053285.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQNK
                     IEVVQQEDVSSEGAGSVENGPEAASVNAQVEEETGDNSNHPSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATHDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KGVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(33255..34079)
                     /locus_tag="VCX65_000812"
     CDS             complement(33255..34079)
                     /locus_tag="VCX65_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP5053286.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKAVADAVTTLTNDESGVAEAVKTFILEEES"
     gene            complement(34083..34880)
                     /locus_tag="VCX65_000813"
     CDS             complement(34083..34880)
                     /locus_tag="VCX65_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP5053287.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYHGEILFADMMTKEQYTEVAKKVLANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            35184..36310
                     /locus_tag="VCX65_000814"
     CDS             join(35184..35418,35418..36310)
                     /locus_tag="VCX65_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612023.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP5053288.1"
                     /translation="MSTVKRYDEEFKQSLVNLYQTGKTQSELCKDYGVSASALAKWIK
                     QYSQVKLEDNSVLTAKQIQELQKRNAQLEEENLIPKKSKCHIHAKLKVRLLAVYRLRF
                     EHDTTTLCRVLRVNRSTYYKFLKHKPSKRELDNQIYRKQILEIYTKANKRLGVKSIKV
                     ILQRDYDTKISEGRIYRLMKNMALPKMATVKPKTALKRTQKTYPQNLLNQKFNPDKPN
                     QVWSTDFTYISIGYKKYVYLCAILDLYSRKCIAWKLSHHMDAKLACDTLELALNKRKI
                     EGTLLFHSDQGSQFKARKLRKIIDDNTIMHSFSKPGYPYDNAVTEAFFKYLKHRQINR
                     KKYQNIKQVQLDCFEYIENFYNNYNPHTANLGLTPNQKEEN"
     gene            complement(36752..37525)
                     /locus_tag="VCX65_000815"
     CDS             complement(36752..37525)
                     /locus_tag="VCX65_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HEP5053289.1"
                     /translation="MGLLDLIGRKRARDKPQNSYEGQDFFYLFGRTTSGENVDEFKGI
                     KVEFIQLSNKNIFDVLEKDLSKKLRFEDISIEAILGKYLCNNDIEIIKYLYEKDKINM
                     ELLISLISKISNKLVKQEFIKVLVLYEYVKNFLPADCIYFSLSNLYGTGHYSSMNYKI
                     FIRTKSGDIFDIADGGRIDDMVSKFNKVNVLGVCMGIGTTVLSQEIEYEIEDRIMILV
                     EKIDVKIYKNCLELANKLSGYQSFFNMNYIRDIIILLFD"
     gene            complement(37630..37902)
                     /locus_tag="VCX65_000816"
                     /pseudo
     CDS             complement(37630..37902)
                     /locus_tag="VCX65_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(37921..38226)
                     /locus_tag="VCX65_000817"
     CDS             complement(37921..38226)
                     /locus_tag="VCX65_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEP5053290.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADNLLERLSQEM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            complement(38226..38528)
                     /locus_tag="VCX65_000818"
     CDS             complement(38226..38528)
                     /locus_tag="VCX65_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEP5053291.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLIFSFEDAKTGNRKDVREFLSQLKENA"
     gene            complement(38583..38759)
                     /locus_tag="VCX65_000819"
     CDS             complement(38583..38759)
                     /locus_tag="VCX65_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEP5053292.1"
                     /translation="MGQNVVMRQAPGGNIKPDKEKSVEKIDGIVGLILGLDRCIRRQG
                     DEASVYDERGILSF"
     gene            38775..39668
                     /locus_tag="VCX65_000820"
     CDS             38775..39668
                     /locus_tag="VCX65_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053293.1"
                     /translation="MTTMLDFPFHHEFIEFLGRWTHILITLLKRHHGQADTAIPRYLL
                     VTIREKTGIVKSTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPGCDRPLILTSGN
                     LAAENYEVSAIEKDKDAEPLNLIALCPDCFLTYQADSRKKIVTALKNVKKILVSAHNS
                     QQAISDMKLDSGIVSVLTSLNKLKCDEYDISYDSKQLTDKISPENNRTLYQLVKNPVI
                     DNYLTIQKIIVNLDKQGKIDYEEIQYQTRSMYKKLKAAKHNNLAIFNTISEKLHKATL
                     QDIYFCQTIVSYFIQKCEVLE"
     gene            39668..39892
                     /locus_tag="VCX65_000821"
     CDS             39668..39892
                     /locus_tag="VCX65_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053294.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSGNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            39883..41541
                     /locus_tag="VCX65_000822"
     CDS             39883..41541
                     /locus_tag="VCX65_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEP5053295.1"
                     /translation="MLIEMWSPVFKNHGEIRESICFHYGLNVIMGMDLADNSIGKSSS
                     LLAIDFIFGGNSYLKSIAVKKLGDHPIYFCFQFEKKFYFSRDTANPDIILVCDKSYSP
                     TGETMDLGIFLNKLKKRYHLDSPELSFRLAMSGFFRIAGKSNQNTDFPLQVYSSQKSS
                     ESITTLIQLFNLYDNIARYKERLKDKSDQLTTFRNARKYTFISNLVGGKKQFEANVSE
                     IKRLEYDLAHLQDTHQDKIDSDDIEKNQQKLQLRNTKLELESSLRDKQRRLKLLDISI
                     EFGLYPTESDLTELQQYFPDTNLKKLYEVEAYHKKLETILDSEFSTERESLIAEIDEL
                     ESQLTTLNQELQELGNIPNLSSEYLESYSKLTATINALKEQNEAYLKESGLSKEKSEA
                     DADLKRSTEDILLDLEVKINSKMREFNNILYPDIRKAPQINLNAHNSYSFYTPDDDGT
                     GTKFKGMIVFDLVMLYLTNLPALTHDSLLLSNVSYQATEALLKLYDQSRSLNKQVFLA
                     FDKASSYSPDANQLLSENTVLRLSSNGNELYGISWNKGENSDEI"
     gene            41531..41740
                     /locus_tag="VCX65_000823"
     CDS             41531..41740
                     /locus_tag="VCX65_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP5053296.1"
                     /translation="MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLEICIALDCKIEDIVEIVDNNI"
BASE COUNT        12798 a         8800 c         7330 g        12834 t
ORIGIN      
        1 gcagttcaag ttttttgagc atcaaactgg gtttgtctat attctaaaat ctccttaaag
       61 gagattttag aatattattg aaattgcttg atatttacaa ctttactatt ttcttttcga
      121 gtgtcctttc gataagataa ttcagcttct ttaaatatat catctcgctt ttcgctagca
      181 tcaatattta gtacaaaacc cactgcaaca gataagacaa gtaagctatt tccaccttga
      241 gacaaaaaag ggaaggtaac accagtagat ggaattaagc ctgagatacc accaatatta
      301 acaaagactt gcatgagcat cataccgcct actcctaaag ccatcatggc attaaaagga
      361 ttttttgctt taataccaac attcataata cgtaaaatta agaagaaaac aagtgccaaa
      421 ataaaccctg ctcctattag acctaactct tcaatgacaa ctgaaaagac aaagtctgtc
      481 tgtgcttcgg gcaaatagcc acgcttttca atggaatttc ctaacccttg gccaaaccac
      541 ccaccattac tcatagcata gtaagaattg gctaattggt gacctgaatc ggtcaagtca
      601 tgaaaaggat taaaaaaggc actaaaacgt ttagcgacat agccaaaaac aggaatctta
      661 gcaactcttt ctaccccaat aacggcaata gtcccaagaa agaccgtaga tagaccggta
      721 atcatgacta ggatagccga aaaccatcgg taaccaatgc cactgataga aaacataata
      781 atggctgtca atacaataat ggaagcattt cctaagtcag gctgagcagc aaccaaaagt
      841 accatcaaca aagaataaac acgccagtcc cgtaaatcgt tccattgtgt tggccaccat
      901 tttcgacgag ttagtgcttg ataatcataa aggctaatgt ttttttggat cttagcaaag
      961 gtcaatgcca aataccatac cataatgatc tttaaatact cagcaggctg aaagctgact
     1021 ggtccgatca caatccaacc atgcgctcct ttgatagcag ttgtaaagaa gcgggcaata
     1081 attaaaagaa aggcctctcc taacataacc acagttaata cccttgtatt cgttaaaaaa
     1141 tttaatttta atttatagat aaatgtaata gccactagac ttattatcca aaaaactccc
     1201 tggttaatca ccgatttaaa tggattagca tgtgcttgaa tcaagctgac acttgtggtt
     1261 gagtaaacca ttattaagcc tatcaccgat aaaattaaat aaggcaataa tatagaataa
     1321 tttaagaggt gccttttatc aatcttcata gttttccctc tacttcttga gataatcatt
     1381 tagcattata acatctttct atatcaaaca aaagaaaaag tcaagaatcc tcaaaaaaag
     1441 aagctccaag ggctaacctt taaaattctg attagtcact tgaaaacttc tataaatacc
     1501 aattaatact caagagcatt agcctgaatt acgtaaacca gtcgctatgc cattgatagt
     1561 tgtatggatc aatttttcat cattttcgtc aagttgatta ttacgccaac gtttaatcaa
     1621 ttcaatttga atatagttca acacattaaa atacggcaag cgtgacttca agctatgctt
     1681 aagggaagga ttatcctcca atagatcatc atggtcttgg atagcaagaa taacattttt
     1741 tgtcaattgc cactcatcca aaatttcata aaaaacatct cgaacatcct gactttcagc
     1801 tagttgtgca tactgaaagg caatattcat gtttgattta gataatacca tatcaacatt
     1861 tgataacaag gaatggaaaa aaggccacgt ctgatacatg tgttggaggc gttcaaggtt
     1921 accttgtgct cggtcaatat aacgtttaaa ggctgaacct accccatacc aacctgggaa
     1981 catgatgcga ttttgtgacc atgaaaagac ccaaggaatg gcacgcaagc ctgtaatttc
     2041 cgtaatcgtt ttacgggctg ctggtcttga cccaatgttg agactggaaa cttccttaat
     2101 cgggcttgcc tcaaagaaat aatcatagaa atggggattg tcaaaaacca attttcgata
     2161 aatggtattg ctatcagcaa caatgctatc catgatttct cgaaaactat caatctcatt
     2221 aggatctgtt atcatttgag tcaccatacg attgatagaa gctgaaatca acatttctaa
     2281 atggtaataa gccacatctt tattgccgta tttgttttca ataatttccc cttgctctgt
     2341 cagacgaatc cgatctttga tggaaccaaa aggttgtgaa gtaatggcat cataagaagg
     2401 gccacctcct cgaccaactg ttcctccacg accatggaag aaggtgattt tcactccatg
     2461 ttcctcacca atagccgtta attcattctg agctttataa agagtccaac ccgatgccaa
     2521 gtagccacca tctttattac tgtcagaata gcctaacatg atttcttggt aattacgatt
     2581 cgttgcaatc caagatttga caatgtcatg gcttaaatag gctgccatga tgtcacgggc
     2641 attatctaaa tcctcaatgg tttcaaagag gggaacaatt tgcacacgag cccgctgctg
     2701 gtcaaccaat cccacttctt taagcataat ggccaactca aacatatcag agacactttc
     2761 tgtatgtgaa ataatatgtt gctttataac ctcttctcca agcttatctt tcaattctcg
     2821 tgccgtagta tagatagcca gttctttttc taataggtct gatttagcaa ctgccgctga
     2881 ggataaagtc cttggctcct ccattaattg ttgtaagaga acatcgcatt tttcagtttc
     2941 tgaaagagag ctataatcgt caacaatatt ggctcctttt aataactctg ccacacaaga
     3001 ttcttggaca ctggagtctt gcctcatgtc aatgcttgct aagaagaagc caaaaatatc
     3061 aacagcttgc atgacttctc gcaaatcccc ctcaatcaaa gcggagttgc cattatcaag
     3121 tagcgactgc tcaatagcct ttagatcagc tttaaaatca acaggagagt cataggctaa
     3181 gatgggattt tctaaactag ctggtgaaga ccaagcagat gtgcttagtc ccacactact
     3241 actcatacga gctgctggct gattagttag ttgaatttgt gtttgtttaa gacgcgattg
     3301 aatataatga aaagctctgc gataaggttc atttccacgg taaatcgatt ggtcctgaga
     3361 caaactggct aaacgttcca cttccgagtt gggttgtacc aaggtcgacg acagtgaaaa
     3421 tgttcggtaa agggctgcta atttgtcaat gtagtaattg aggataacct cactttgaac
     3481 cgtagctgac aagcacaagg tttcagctgt gacaaagggg ttcccatcac ggtccccacc
     3541 aatccacatc cccatggtaa tgggtttggg attgtctaac tctagaccgt gtttttgggc
     3601 taagtttttg tactctgttg tcaacttggt cactgcttga atgagagaac catcgtaata
     3661 ctgcatgaca ttttttatct cgtttttcac ctgaagcttt ttctcgcgaa taatatctgt
     3721 ctgcatgatc atttcaatat aacgatatag ctcctgacgc catttctcaa gattaatcac
     3781 accagcctta gcatcacggt atttgcgcag aagtttatga atgtgagttg tcaattccag
     3841 aatcgtttta cgttgtactt gcgtcggatg tgctgttaaa acaggaacca cattaacctg
     3901 ctccaaaatg tctttaccat tatcttttcc agcaagatcc ttgatggtta gggctaattt
     3961 tcctaaataa tcagtatccg tattattttg ataattgatt tcataggcta aatcgacatc
     4021 ttctgaaata ttgattagca agggtaaaat agaaaaatac ctggaaatca cttccatttc
     4081 ttgatttgaa atattggcga caactttttc taattctatg taatcttgtt tttcagataa
     4141 caccataata gactcgataa ctgcaaacgc atcatctcca atcatccgtc gtgtgatatt
     4201 ttccaacatt tctttcaaaa gagcaacttc ttcagcaatg atagcttgat tgttactact
     4261 ctctaacttt ttaagtggca aatgaccatc tccttctttg ctagtttctt ctatcatacc
     4321 actttttacc aaaaataaaa gtgatcatgt taaaaacgtt tgttttttaa caaaagtaag
     4381 cgctttattt taaagaatgt ttggataggt ttagtctcca tattccacta aaattctgtt
     4441 atactagtct tgactatatt gttaaggaga caactatgga attgaaaaaa cgttcagaat
     4501 tccctgaaaa tgaactttgg gatctaacag cgctctacaa agaccgccaa gattttttac
     4561 tcgctattga aaaagcctta caagatattg acctgtttaa gcgcaattat gaaggccgct
     4621 taacgtcggt ggacgatttc actcaggcct taatagaaat tgagcatatt tatattcaaa
     4681 tgagtcatat tggcacttat gcctttatgc ctcaaaccac tgacttttca gatgaaagtt
     4741 ttgctcaaat tgctcaggct ggcgatgatt tcatgactaa agctagcgtt gcccttagct
     4801 tctttgacac cgccttagcc aatgccgacc ttgacgtgtt agatacatta gaaaagaacc
     4861 cttatttcag cgcagctatt cgcatggcaa aaattcaaaa agaacacctc ttaagtcctg
     4921 atgtggaaaa ggctttggct aacttacgcg aggttatcaa tgcgccctat gatatttaca
     4981 ccaaaatgcg ggctggtgac tttgacatgg aggattttga ggtggatggt aaaacctata
     5041 aaaatagctt tgtttcttac gaaaatttct atcaaaatca cgaaaatgct gagattcgtg
     5101 acaaagcctt ccgctctttt tcaaaaggtc tccgtaaaca ccaaaataca gctgcagcgg
     5161 cttacttagc caaggttaaa tctgaaaaat tgttagcgga tatgaaaggc tacgcttctg
     5221 tctttgatta cctcctagct gaacaggaag tggatcgtag cttattcgac cgccaaattg
     5281 acctcatcat gactgaattt ggaccagttg ctcagaaatt cttaaaacat gtcgcccaag
     5341 tcaatggtct tgagaaaatg acttttgctg actggaagct agatattgac aatgatctca
     5401 atccagaggt cagcattgat ggtgcctatg acctcgtgat gaaatctcta gccccattag
     5461 ggcaagaata cacgaaagaa atcgaacgtt atcagacaga acgctgggtt gactttgctg
     5521 ctaacgccaa taaggattct ggtggctatg ccgctgatcc ctacaaggtt catccgtatg
     5581 tcttaatgag ttggactgga agaatgtctg atgtttatac ccttattcat gaaatcggtc
     5641 actctggtca attcattttt tcagataatc accaaagtta cttcaacacc catatgtcaa
     5701 cttattacgt cgaagcgcca tcgaccttta atgaattgat gcttagtgat tacttggaac
     5761 atcaatttga tgaccctcgt caaaaacgtt ttgcccttgc tcaccgttta acagacactt
     5821 actttcataa cttcatcact cacctattgg aagcggcttt ccaacgtaag gtttacaccc
     5881 tgattgaaga aggcggtacc tttggagctg accaattaaa tgcgatgatg aaagaggtct
     5941 taacagactt ctggggagat gccgttgaca tcgacgatga cgcagctctt acctggatgc
     6001 gccaagcgca ttactacatg ggcttatata gttataccta ttctgctggg cttgttattt
     6061 caacagctgg ttaccttaac cttaaaaaca acccagatgg ggcaaaagaa tggcttgact
     6121 tcctaaaatc aggtggcagc cgtacgcctc tcgatactgc aatgctcatt ggggcagaca
     6181 ttgccaccga aaagcctctt cgagatacca ttcaattctt gagtgatacc gttgaccaaa
     6241 ttatcaatta caccgaggag atgtcacatg cctaatctct atgattttac ggttaaggct
     6301 caaaatggaa atgacctttc cttagctgct tataaaaaaa aggttgtttt gattgttaac
     6361 acagctacca agtgtggatt aaccccacaa taccaggccc tgcaagcact atatgacaca
     6421 taccatgaca agggatttga ggtcttagat tttccttgca accaattttt aaatcaagct
     6481 ccaggagatg ctgaggagat taatcacttt tgcagtctga cctatcacac tactttccct
     6541 cgctttgcta aaatcaaagt gaatggtaaa gacgctgatc ctttgttcac ctggttaaaa
     6601 gaagaaaaaa gtggtcccct tgggaaacgc atcgaatgga atttcactaa atttctcatt
     6661 gaccaaaatg gtcaagtcat taaacgctat tcctcaaaga cagatcctaa actaattgaa
     6721 gaagacctta aagcacttct tggttaatat aaaatagact tggcgtgcca agtctatttt
     6781 gtattaatag ttactattta aaaacttctt gataaaattc aatgctatca ccatctttaa
     6841 cggtaatttg atcggcaccc ttatctgcca tctttccatt caccttaaaa agccagtatt
     6901 tgttagcttt cgtgtcttgc tcaataccat caattgctgt gataaagcca tctttttctt
     6961 tgacctcata attatctttg agaatctcaa gcaccgtatc tccttttcca aaagaaactt
     7021 tttcatcaat ggtattggta tcttctttga caactaagcg aacgtgatgg tctgcttttg
     7081 gaacgcttgg agtctgtgtt tgttttgttc cttgcgagca agcaacaagt agcatagcaa
     7141 caagcgctag aaatcctgtt ttaaatcttt tgttcaccga ttaacctcct aaataacatc
     7201 atcacaactg gaaaaaagac gagagttgat aaagcatgcg ctatattaaa gggcatccct
     7261 gctaaaacat aactccacca aggcatacta tacaaatacg caaaacaagt atctatcaac
     7321 accccataaa ggaggccaca taaggcggcc aagaaagcct gataaccaag ctgatatttg
     7381 gggaattgct gagacaaagg gtacaaggca aaacgccata ataaaagaac aagcacaaaa
     7441 caagtaactt gccaaaagac ccaagggcca aatcccagca aaaaggctga taaaaacaag
     7501 cacaacatca taactaatac agcctcggct aacccaaagt aaagaagata actgagtaaa
     7561 aatgccgtca caggctgcac attaggcagg ctgctaaaaa ccattctcaa cacaacacat
     7621 agggctgaca tgatagcaat gcgactcata aacttagctg acataaactt cttcctcgtt
     7681 tttttctcta ttatgacaga tttacagagc gtttaccagt ttgaagctca cttatttatc
     7741 aaatgataat aacatgagaa ttaaataaca aaacagtact tgctgactgt catgatatag
     7801 tcaaagacta aactaatatt gtaaagaata tagctaccaa ctataagaga tagtgacata
     7861 aacttgacat agttagagag gatctcattt gtaacttata aaagataata ccttaaaatg
     7921 caagataata taagaaaaca gttaggatat tttgattttt tttagtaatt agggtacaat
     7981 aacagttaat gagaagaaaa ataaaaccta ttgttgtgct agtcttcttt attttactgg
     8041 caatggtatt gattatcgga aaaagacaag ctaatcatgc gaaacaaaaa gaagttgaag
     8101 acgctaagag tcatattcct attgcaacca gtaatcctag taaagcaaaa actagcactt
     8161 ctgaaaccga agactttatt ttaaatccta ttgttgatgt ttccggctgg caactccctg
     8221 aagaaattga ttatgacaca ttgtcacgtc acatctctgg cgcaattgta cgtgtctatg
     8281 gaggatcgca aattacagct cataacaacg ctgcttttac aactggaatt gacaaatctt
     8341 ttaaaacgca tatcaaagaa tttcaaaaac gaaatgttcc tgtagctgtt tacagttacg
     8401 cacttggtcg tagtactaaa gagatgaaag aagaggcccg agctttctac aaaaatgctg
     8461 ctccctataa tccaacttac tactggattg atgtcgaaga agccactatg aaagatatga
     8521 ataaaggcgt aacagccttc cgagaagagc ttaaaaaact tggtgctgaa aatgttggtc
     8581 tctatattgg aacttatttt atggcagaac aagatatttc aacaaaaggt ttcgatgctg
     8641 tatggattcc gacttatggt agtgattctg gctattatga ggctgctcct aatacaacct
     8701 tagattacga tttacaccaa tatacctcac aaggttatct cagtggtttt aacaatgctt
     8761 tagatttaaa tcaaattgcc gtaacaaaag acactaaaaa aacgtttgag aagttatttg
     8821 gcaactccaa caattaagag gttagcatca tggctaatct ttttttatag tttacatctt
     8881 accaagaaaa actctaggtc aataatttaa aaccccttat ccttgacaag gagattatct
     8941 catcatataa tgaaagcact ataatatttc acaaaggagt gctttggctg agatcgcaat
     9001 tgcgaaatcc tgaggacctg atcttgttag tacaagcgta gggattgtga ccaataatca
     9061 atgattggaa agcgatactc tttttgtgca caaaaggagt tttttatgtc accaaacacc
     9121 aatgtcaaat accttatcga agctgctatt tttgctgcac tggcgatggc cctttcattt
     9181 attccagatt ttgctggctg gtttagtcct tcttatggtg ctattgcact ggttattttc
     9241 tctttgcgcc gtgggttaaa gtacggcatg ttggcgggtc tcatttgggg gctgcttcac
     9301 tttgtacttg gaaaagttta ctatctcagc atgtcccaag tctttattga atatatctta
     9361 gcctttacct ctatgggatt agccggtagt ttctctgata gtttgattaa aactttaaga
     9421 agacaacaaa ccttttttgc cgtttttctt gcaataatgg ctagtttact agccgttaca
     9481 gtacgttact tgtggcactt ccttgcagga atcattttct ggggcagtta cgcccctaaa
     9541 ggcatgtccg ctgtctggta ttcttttagc gttaatggta cagctggtgt cctaactttt
     9601 ttaataacat gtttagcgtt aatgattgct ttaccaattc atcctcaatt atttgatccc
     9661 aaagactaat ttttagtcat ttgaatctta cattaaaaaa atggtataat aatgttgtta
     9721 taccattttt tatgtttaga taaaggtaag gacttgatat ggctaaaaaa acaaaattca
     9781 aaaaaacctt agtagaacaa atcctcgata aggctaatat tgctcatcaa ggactcaagc
     9841 ttaatgcttt agaaggcgac tttccagatg atcttcagcc atcagatatt tacaagacac
     9901 ttgctctgac tggtgatcaa acaggtcctc taattggcat tattccatta acagaacact
     9961 tatcagaaaa acaattggca aaagtatcag gtaacaaaaa agtgtccatg gttcctcaaa
    10021 aagacttgca aaagacaaca ggctatattc acggtgccaa taatcctgtt gggattcgtc
    10081 aaaaacattc atatcctatt tttattgacc aaactgcact ggaaaaaggt caaataatcg
    10141 tttcagctgg tgaagttggg cgttctataa agatttctag ccaggctcta gctgatttcg
    10201 ttggcgcaag ctttgctgat ttaaagaaga gaaaatgaac actactgcca actttatctg
    10261 gtttcttttt taagtttttc gccttgatta agctagtctt tgtttagtat tattttgatc
    10321 tcaactgctt taacattgat cctgttaatc tttttctttt gtaaaggctt gatatcacga
    10381 caaattcagg tcgatttgtc ttaaatctaa tatgggcttt acactttaat cagaacctag
    10441 ctattataca cttatactac gcttttttac tttatctttt cactataggt attatttttg
    10501 cttggtgatg cctaaacttt ttctggttac ttttttattt ttagcgctcg catcagttat
    10561 ctctaaaagg aggcttaaat gaaattatat tttgtaagac atgggaaaac cctttggaat
    10621 ttagaaggtc gctttcaagg cgctgggggc gattcgccat tacttgaaga ggcaaaagac
    10681 gaaattcact tacttggcaa agagttagct aaggtggctt ttgatgccgt ttatactagc
    10741 gaccttcaaa gagctatggc aacagcagct attatcttag atgcttttga ccaacagcca
    10801 aaactttacc acaccgacca gcttcgggag tggagattag gtaaattgga aggggctaaa
    10861 atagcaacaa tggcagctat atatccccaa caaatgctgg cttttcggga gaatctagcc
    10921 cagttcaaat cagatcagtt cgaggctgaa tcaatttacc aaacgactca acgtgtctgc
    10981 catcttatcc aatcgtttaa agataaacat tatcaaaacg ttcttattgt aggacacggc
    11041 gctaacttaa cagcaactat tcgctcatta ttaggttttg aacctgctct tttactcgct
    11101 aaaggtggct tagataatac cagtcttact attcttgaaa ctaaggatta tttaacttat
    11161 gactgtttaa tttggaatga taaatccttt ctagaggtgt aaaaccacta gacaataata
    11221 aaaaaagcta acacattgat ttcttactga caagacactc actttgctag ctttttttat
    11281 tattatctag tgggctatta tggtttcatc tatctggcat attttaagcg caaaactttt
    11341 tcttgctgct tggttaaccg aagcaagata accaccttgt caatgctcat gttactttca
    11401 agtaaacgct ctgctgccat catcaagcca ttattgattc ccatctgtaa aattggattt
    11461 ttcttgtcat tgacatcaaa aataaattta ttatcaggta aatcaaagag tactttaacg
    11521 gcaccaaaga gctgttcaaa gttatcaata gccacatcat aaacaggctt agtgcctggt
    11581 tttagctgac gacctctatg attaaaccac atggaatgcc aaccaccatt aaaggcaccc
    11641 atgatatcat tgtcataaga gtccccaaca tatagtgtgg tttgtgggtt catgtcaaat
    11701 tgttctgctg ccaggttaaa aatttctttt tctggttttt gaaagcctgt tgcttggctc
    11761 acaatgacac gcttaggatc aatataatca taaagcccta atttacgaac ttttttcagc
    11821 tgatgttctg tgggcccatt ggtaataatc cccataggaa cattctttga ttttaaaaag
    11881 tcaagggtca tacgcatctc atctaacatg gtaatgttct caagttcgtg ctcatagact
    11941 tcttgaaaat gtactcccgc agcttcgtcg atttctcgat agccaaactc aagcagtgtt
    12001 tccttgcaac gccagaatcg gaaatattct gtggtccact cccctgccat tactcttggg
    12061 aatccaacat ctgaatagtg acgaaagcga atataagctt gattcattac tgacatatca
    12121 aaatctggga agcacttttc catggcgatt cgataaggcg cttgctggtc gtaaattgtg
    12181 tcatccacat caaaaacaat agcagtaatc atgagtctct tttcttttct agtttaatat
    12241 cccaatcatt atactatttt ccattaggct tttcaatttc attttcaaaa aaatgccccg
    12301 ctgcagtcgc attttccaac gaaatatagg tgtattctag ccccttttat gatacaatgg
    12361 aaaggaaatc gtattggagg aaaatatgtc taatcaacac atcgaagaat taaatgacca
    12421 acagattgtc cgtcgtgaaa aaatgacggc gctggctgaa caaggaattg atcctttcgg
    12481 taaacgcttt gaccgcacag ccaattctgc tgaattaaaa gaaaagtatg ctgataaaac
    12541 aaaagaagaa ttacatgagt taaacgaaac agctattgtt gctggccgct tgatgacaaa
    12601 acgtggcaaa ggtaaggttg gttttgctca tcttcaagac cgtgaaggcc aaatccaact
    12661 ttatgttcgc aaggactctg ttggcgaaga caactatgaa atcttcaaaa aagccgattt
    12721 aggcgacttt atcggcgttg agggcgaagt catgcgtaca gacatgggcg agttgtcaat
    12781 caaggcaacc aagttgactc acctttctaa atcacttcgt cctcttcctg aaaaattcca
    12841 cggattaact gatattgaaa ccatttaccg taagcgtcac cttgatttaa tttcaaatcg
    12901 tgaaagcttt gaccgcttcg tgacccgttc caaaatgatt tcagaaatcc gtcgttattt
    12961 agacggtctt gatttcctag aagtagaaac gcctgtgctt cataacgagg ctggtggtgc
    13021 tgctgctcgt cctttcgtta ctcaccataa tgctcaaaac attgatatgg ttcttcgtat
    13081 cgcaacagaa cttcatttga aacgtttgat tgttggtggt atggaacgtg tctatgaaat
    13141 tggtcgtatc ttccgtaacg agggaatgga tgctactcat aatcctgagt tcacttctat
    13201 tgaggtttac caagcctatg cagactatct tgatatcatg aacctgacag aaggcattat
    13261 ccaacatgct gctaaagctg ttaaaggtga tggccctatt gattatcaag gaactgaaat
    13321 ccgtatcaat gaacctttca aacgtgtcca catggtagat gctatcaagg aagtgacagg
    13381 tgttgatttc tggcctgaaa tgactgtcga agaagctatt gcacttgcca aagaaaaaca
    13441 ggtcccactc gaaaaacact tcacaagtgt cggacatatc atcaatgctt tcttcgaaga
    13501 attcgttgaa gaaaccttgg tccaaccaac ctttgtgttt ggtcatcctg ttgaagtatc
    13561 gcctttggct aagaagaatc cagaagatac ccgcttcacc gaccgcttcg aacttttcat
    13621 catgaccaaa gaatacgcca atgctttcac agagttgaat gatcccattg accaattatc
    13681 tcgttttgaa gcacaagcac aagccaaaga acttggtgat gacgaagcaa ctggcattga
    13741 ctacgacttc gttgaagctc ttgaatatgg tatgccgcca accggtggac tcggaatcgg
    13801 gattgatcgt ctttgcatgt tattaacaaa cacaacaaca atcagagatg tgcttttatt
    13861 cccaacgatg aaaccttaac ttttttaaga tttgtattca tatcttaaaa ccgataagtg
    13921 gcaatataac ataacgtttt attatctcta accagtcttc attaccatga agactggttt
    13981 attaacagta gcttatagaa agtgacttaa caagatgacc aaagaatata tctcctacat
    14041 tagtgctgct atcttcttgc tttatggcct tttagctgcc aaatggattt ttcttgggct
    14101 aggcttaatt ttggtacttg tcggccttgc tgatcgcctc aattcaaaaa aataatcctt
    14161 ctattcgccc ctgtcctttt aacctagcga tgtcatcacc aggttaaaag gacaagggcg
    14221 aacgagggat tatgtttcga ttaaggtaac attacttacg aaaagcgtct aagatggttt
    14281 taaattcttc attagtaaga gtaatgcctt tccccatttt cgtatggtct ggactccacg
    14341 tgcggatatc ccatttcgct tctgcgccat taaagctgac gcggttcaat tctttcgtcc
    14401 aacctttatc attttctgat aaggtgagta aatgttcctc aatgttgaat gtaaattctg
    14461 ccattagttt tcctcctcat ctatactatt cgaaattaaa gtggaaaaaa tcatcttttt
    14521 ttcacttttt ttatgactca ttctcctatt attctatcaa gttttgagaa aataagctat
    14581 tgtgatatcc aattttcaaa aaaaaaaaaa aacaggctct cttttcccaa ctatggtcgt
    14641 ataccatttg gaaaaagagg gcctctaata tttcttgtta ctatgttcta acagttttac
    14701 tggtgccatc tttttgatag aggttgacaa ggccttcctt gcaagcccta atcatatccc
    14761 ctggcttaac ttctctcggt aaagagatgg ttaagagttc cattggattt ggggcacggt
    14821 caatcttttg gccatccgca tcatgtaagt ccttaacaac cgtttcaaaa tgacggaaac
    14881 ctggtccata acattcaatc cgatcgcctt ccatgatgac attacgctga cgaatggtcg
    14941 ctgtcatgct agctgagtca aaggcaacta cttctccgac aaatttatat tgtggaattt
    15001 tgcggcgagc accaaataat tgttcatttt cagttgggat accataataa aaacctgtag
    15061 ccaactcgcg ctgggcaacc ttccacaact cgtcaatcaa ttcctctttg atagcataaa
    15121 aagcttctgg gctttccatg taagcatcta cagccgcctt gtaacagttg gttacggttg
    15181 agacgtagtg gatagatttc attcggcctt caatttttaa gctatcaacc ccattttcaa
    15241 tcaggtcagg aatatggtca atcatacaca tgtcaacaga ggacatagaa tagtcttctg
    15301 gaatttcccc ttttaaggag cggcgctctc ctccaaatgg catgtcatac aaatcatact
    15361 tccagcggca agactgtgag cagccgcccc tgttggcatc acggtgactc atgtggtttg
    15421 acaaaacaca gcggcctgaa taagaaatac acatggctcc atggacaaag gcttcaattt
    15481 ccacatctgt ccgcttacgg atttctgcta actcggccat attaacctca cgagctaaaa
    15541 caactcgggt caaacccatg gctttccaaa attcaaaggt ctcgtaattg gtagatgaag
    15601 cttgcgttga caaatgaatt tccaaacctg gggcttctgt tgaacaaata ataatcaagg
    15661 ctggatctga aacaatgacc gcatcaagcc ccatatcacg cagttgacga aaccactcgc
    15721 ccgcaccaat ttcgttccct tcgtgggtaa ccatgttggc agcaacatag accttagctc
    15781 cacgcgcatg tgcataatca atgccttctt gcaattcttc catagagaag ttaccagcgc
    15841 ggcttcttag accataggcc tgtcctccaa caaaaacagc atctgcgcca tagtcaatcg
    15901 caacttttaa tttttcaagt gttccagcag gtgataagac ctcgggacgt tttttcatat
    15961 gtgacatgtg atattctttc tattttcaag ataggtagat tacctgtgta atggtgtcat
    16021 aaccctgtct tgccctgaaa tagtaaactc actcaagaca aggattactt atttaacggt
    16081 ttttggatcg aactcataaa agccagtatc taatccacgg ccagctggat gatgggcatg
    16141 cactgcttga tcaagctttt cagcttcttc ttgggtaaat tgcccagctt ctaataaggt
    16201 tttagcctga ataaacaatt tagtaatagc gacaaaatca tcacctggac agtaaatgcc
    16261 atctagcttc caatgagtta agccatgcgc atacagctca cccaatttag acatcatgtc
    16321 gatatcgtta ttaatgaaaa tatgagtgcc atgattgtct tcataaatgg agtaatggct
    16381 gctagcatct cctggttctg ccaagaaaag tcctcgttca cgactaacct catcatcaat
    16441 ctttgtaaaa tggtaataat tttctagcaa ggggcgtttc gagtgatgaa tcaccgaggc
    16501 gccgtaaact agcacctctg ctggaaattc caaattttca gctaaggtga ataactctgc
    16561 tgatgggatt tcccttgcta aaacactttc aacagcacca tgttgccccc agaaatttac
    16621 ctgacggcta gaagtcacaa aaacagaggt atcataaatc agtttaaagt tatagccatc
    16681 ccttttattg acataaaaca cacctgcatc accaaccaca agataatcaa cagcaatctc
    16741 tatcattaag tctaaaaagg gtttgatctg atccatcata tcttgatgca tcaaagcatt
    16801 gcaagctact gtcaactctt tgcctgcatc atgcactagt ttggcaattt gtctcaattc
    16861 atcataagaa aaattatggg gaaggcgtaa cccgtaattg gcttcaccaa cataaatacg
    16921 atcaacacca gcagctaata aagctttgac ttgctcaatg ctttcagctg tggctgtaat
    16981 aattattttt tccatataag ctttattata ccaaaaattt taagacctta agcatatttc
    17041 ttgcaaaagc ccaaacgtta agctagtccc cttactgtta tagcatgata agtcacttgt
    17101 cattagtaaa tcttttcaaa tcttttaaaa aaagatgaca agaagagact tttatgatag
    17161 aattacttag tatgttaagg aaaggagagg actatgcctg caccgttaaa gaagcataat
    17221 tcggttgaac aggatgattc ttaccaagaa tctcaaagta aatttcgaga ttttcaagag
    17281 ttcaatggcc aaagtgcaaa gctaaaagaa ttagtcttct ttgctcgtat cgctagtttc
    17341 agccttatta ccgttttatt tgcatttgtc ctgctcgtaa tgaatttagc gccaatgttt
    17401 gctttcttat ttgcaagcat catcagctta ggcattactt ccttattcgc caaggttatc
    17461 aaatcattac tgatgtaact tccagagtcc gttttacgtg actctttttt ttgtgtcaaa
    17521 aacaaaaaaa gattgaagcc acaatccccc cccttcttca gttagcctaa aactaaccat
    17581 cgggactagt gatcagatcc ttcaatcttt tcttcttcta tgttttaggt cgttttagtt
    17641 agtgtttatc tagtgtatca ctaacaggct catcttgttc agtatagtca atgatgatgt
    17701 cttcttcatt taaatcaatg ataacatcat cttgcttttc tttcgcttca acttcggcaa
    17761 gggtttcttt tgttttttgc acgaaagctg ttgttttatc tttgagcaag tctaacatgt
    17821 cctctttagt taagtcacca gaagccaact tatctttcac atcatagaaa gtgtcacgtg
    17881 ctaaatggct gtattcacta cctttttctt tagcaaattg gtggtaatca tctggacttt
    17941 ctttgtaggc ttgataagct ttttcagcac gatttttcaa agccttgcct ttttctgttg
    18001 ataagaagta agctgccgct actcctgaaa cagctccaat cactaagttt ttgaaacttt
    18061 tattcatgct tttctccttt ttttccaaat acttttgagg ctactttacc aactaatgct
    18121 aattttccag cttttgaaac attacctgta gcattagttg ctttttgccc aaaatgcctt
    18181 gcttgactat ttaaatctga aagactttct gacaaatcag caatagcaac aaacagtgga
    18241 tcgatggttg ctactttacc attaacatct tcaacaagga tattagcttt tgctaaaata
    18301 tcattagttt gatgaagtgt cacattaaca tcacttgtca atacagaaat cgtttttttg
    18361 gcttcatcaa ttgtttctga gactttcttt aatacaataa tcaagaaaat caccaaagca
    18421 acaaatgcga gtgcaataat catcagtgag attccaacta agtccataag tttctccttt
    18481 ttctatcctt attcttgata ataagaaatt cctttttgac ggcgtctttt tatgacaaag
    18541 attaagccaa taataattaa taaggcagac acatattggg agatgcgaat acctaaaaac
    18601 ataagactat ctgttcgcat accttcaatg actagtcttc cactaccata ccaaattaag
    18661 taaaatgcaa agatttctcc atctaataga ctttttggct tacgacgcca catcataata
    18721 atgacaaatc ccaaaagatt ccaaagtgat tcatagagaa aggtcggaat gcggtaactt
    18781 ccctctataa acatttgctt ttgaataaag cttggtaagt aatttaactg gctcacagct
    18841 ttaccatagg cttcttggtt gataaaattt ccccagcgac cgatagcttg agcgaccatg
    18901 acacttggtg cggcaatatc taaaaaatga atgggattga gcaccttgtt ataacagtaa
    18961 gccaaaagta caagagctcc tgtaatgaga ccgccataaa tagcaatacc gccattccaa
    19021 atggctatga tttcatctaa atgcttgaca taataagacc attcaaaaat aacatagtaa
    19081 attcttgcac caacaatagc aagtggaaaa gcaatcagaa taaaatcgaa aatagcgtca
    19141 gatgatattc cttttttggg tgcttctttt gatgctaagt aaaccgccaa aacaagtcct
    19201 gacaagatac atagcgcata ccagtggatg gctagtggac cacattttaa ggcaatggga
    19261 ttgatcattg actcacctca tttttggtga ttagttgagt taaacgatct tcaaaagttt
    19321 ttgtagcatc aaagcccatt tctttagccc gatgattcat cgcagcggct tcaataacca
    19381 ctgaaacatt tcgacctgtt tttaccggaa tacgaatacg agggattctc actcctgaga
    19441 aagttatctc ctcattaccg tttccgagac gatcaaaaac tttaccagcc tcaaagtttt
    19501 caaggtaaat ggccaattga acttgtgatg agtccttcac agcactagct ccataaagcg
    19561 acatcacatc aataatacct accccacgaa tttcaagcaa gtggcgcaag atctctgctg
    19621 gctctcccca aagggtttct tcatctttgg catagacatc cacacggtca tctgcaacca
    19681 aacgatgccc tcgcttaact aattctaaac cagtctcact tttaccaatt ccagaatccc
    19741 cttggataag aacccccata ccataaatat ccattaaaac gccgtgaaca ctagtacgtt
    19801 cagctaaaga agcgtcaaga aaataagaca tttctccagc taagcggcta gttgaaacac
    19861 ggctacttaa aagtgaaata ccttcttctt ttgcagcttg aaccatttct tttggaatgg
    19921 ctaaatttct agagacaacc actgcaggag tgtccttttt gaacatctct tttaaaacag
    19981 aataacggtt gtgagaagtc atctgtgtaa gataagacca ctctttcatt ccaaatagct
    20041 gcaacctttc tggagcataa taatcaaaat aaccagtcat ttcaagacct ggacgtgaaa
    20101 tatctgatgt tgttatctct tttgacaaca agttatctgt agcataaacc acatcaagtt
    20161 taactttttg cactagcatc tttacagtaa cggtcataat ttctcctttt tcaatattat
    20221 aacacaaatc gaccgttaga cccttgcaaa tactcatttt ttcactacta aatgagaaca
    20281 acgacaccaa aaatggtctt agctctatta aaaactaggt tttatcattt agagatatga
    20341 gtcaaaaata agacaatggc aaacaaatac tttactagta tcattgagca attagtgctt
    20401 attatggtgt ttaaaaaggt atcatcttac taagtcaaaa agcaaaaagc ctcatcatag
    20461 ctgataagac ccctcgctta cttacatatc aaaacatttt attatcatca gttaatcaca
    20521 tggttgctct tacgtgatga attatcattt taactgattg tttaccagaa ccagccatct
    20581 tcttcttcat ttaagacatc agcgtcttta cgacgacgag gacctcggcc ataacgttct
    20641 tcaagcaagt cttccttgta aggtaagaag atggccaaca aaatataaag caaaactcca
    20701 aaaccagttc cgtaaataag aagagccgct aagacacgcg ctagagcaag atcccaacca
    20761 tacttatctg ctaaaccagc aataacacct gcaaccaagc gattttttcg ctgtttatag
    20821 aatttagttt ccacgtttct ttacctcctc attctatgat actagtttac attgtttttc
    20881 gcaaaataaa accagtctta cgactgattt ttttccataa gtttcccgtg gcaatttcca
    20941 caaacatatt tagccagatt gatacgcctt tttcgttgat aaacctgccc acaggtttgg
    21001 caactataat gatgattagt ctttgattta gagctagttg ggacataacg aagcccgttt
    21061 acttgagcta gcagatcttt gaaatcccta tctttatgat ggtaccctct tccttcaaaa
    21121 taaagatggt aatggcagag ctcatggcga acaattttcc gaaaaataag ctcaccgtgc
    21181 tcctcaagca tcctagggtt aaaatccaaa tgaccatctt ttggaaaaaa gcgaccgcca
    21241 gttgttttta ggcgcttgtt ccaataagcc ttgtggtgaa atggtttgcc aaaatcagcc
    21301 agggaaactt cttggacata attagtgagt gtcacgcggt ggcaataggc tgagattgac
    21361 cttgtggcgg tccaagtcaa tcttagagac ccaaacagtt accaagtcac ccactgaaac
    21421 aacttgacta gggtggttga caaaggtttt gctcatttca gaaatgtgaa taagcccatc
    21481 ttcatgaaca ccaatgtcta caaaagcacc aaagtcaacg acgtttctca cagttccttc
    21541 aagcttctgg ccaatttcca aatctttcaa atcaaggata tcttgacgta agattggtgc
    21601 ttcaaagtca tcacgaaggt cacgacctgg tttaaggaga tcagcaatga tatctttaag
    21661 ggtttcctgc ccaatagcca atgtttctgc catttgggga acttgaactg ctgctaaagt
    21721 tgccttggca gcgtcgtcca agtcctgaat accaagtacc ttaaagagtt ctttgactgc
    21781 tgggtaggac tcggggtgaa ctcctgtgtt atctaaaata tttttggctc ctggaattct
    21841 gagaaaacct gctgcttgct caaacgcctt agctcctaaa cgcggcactt ttttgatgtc
    21901 agcgcgtgat gtcaatgctc cattttcttc gcggtatttg acaatatttt ctgaaatcgt
    21961 tttgttcaaa cctgacacat gtgctaataa agatggacta gccgtgttca cattaacacc
    22021 gacttggtta accacagtat ccacaacaaa accaagattc tcactcaact ttttctgact
    22081 cacatcgtgc tggtactgac cgacgccaat agatttagga tcaattttaa ccaattctgc
    22141 tagtgggtct tgcaagcgac gagcaataga aatagcagag cgcttctcca ctgtgaggtc
    22201 tggaaactca tgacgggcta actctgacgc tgaataaacc gaagcaccgc tttcgttaac
    22261 gatgacatag gacgtatttg ggaaatcttt caaaacgtct gctacaaagg cttcactttc
    22321 ccgactggct gttccgtttc caatggcaat aatatcaatc tggtaagtct caatgagctg
    22381 agtcagtgtt tctttagctg cttgaatctt cgtttggcta gctggtgcta cgggataaat
    22441 aacctgagta gtcaacaatt ttccagtctg atcaacgata gccaattttg cacctgttcg
    22501 aaaggcaggg tcaaacccaa gaaccatttt cccttttaaa ggagacacta acaaaagatg
    22561 acggagattt tcagaaaaga ggtggatagc cccatcttct gcggcatcac tgagttctga
    22621 acgaacccgt ctttccatag ctggaacaat tttctttttg atggtctgat tgatgacctc
    22681 ttcaatataa gggttggttt ctttgaaccg cacactgaaa aagcgttgca ttttctccag
    22741 gttatgctca aaagacactt ttaagatgcc taacttttcg ccacggttaa gggctaaagt
    22801 acgatatcct tgcatgttag acacttggtc agaaaaatcg taatagattt ggaaaacctt
    22861 tttctcatcc aactgctcat ctttaagcgt tgatactaaa cggctgtact gccaaatctc
    22921 attgtaggtc caagagcgta atttagcatc ttctgacatg gcctccacaa gaatgtccac
    22981 agctcctgct agagcttctt gtgggctggc aaatccttct gtgacaaagg gttctgctgc
    23041 tgtttcaagg ttttgcgcat tttgtaaaat caaacgtgct aatgggaaca agcctgcttc
    23101 acgcgcaatc gtcgcttttg tacggcgttt ttccttataa ggcaggtaca actcttccaa
    23161 atcagcgagt ttttcggttg cttcaatact cgttcgtaac tgatctgtca gttttccctg
    23221 ttcctcaatt ttagcgagaa tggttgcttt gcgctcattc agggtagtga gagacttatc
    23281 catatcaata atggacttaa tcaccacttc atctagattt cctgttactt ctttacggta
    23341 acgtgcaata aagggaatgg tattgccttg tgctgttagg gcaagcacct gttcaatttg
    23401 atggagacta actgacaaag cctctgcaat gttgtgatta ttgttatttt ccataatatt
    23461 gctattataa cacaaaccat gttaatgcaa aaaatgatag cgaaacattg tcctaatata
    23521 aagttgcgta aagaatcaaa aaaagctact tttagtaaat aactgacgaa accctaaata
    23581 acaataccta attttaaaaa agaaagaagt aaacagcact tccgctttgg cattgttctc
    23641 aaatgatagt ataatagact tatcttgaat gaaagaaggt catagatatg gcaattaccc
    23701 ataaaaaaaa tgatgaactt gaaaaaatgc tagcaggctt tgcatcaatc cctagttttg
    23761 ataagccttt ggaagtcaat actgatggta aactagcgac caaagaaaaa acgacagaac
    23821 aaacaaaacc aagcaaacca tagctagttt gtctcattct cttaacatat cgtccattcg
    23881 tttaaactga gttgagagat ttttagcgat caggctaaca aaacgtatca gtcgaggctg
    23941 aacattcgtg tttcagcctc ctcttttatc atctagaaag gatatggtga atgtcactct
    24001 tttccaacct tcctcccagt gtcttgcaat ggtttgcgat ttttatgtcc attatcattg
    24061 aagctcttcc ttttgtgctc ctaggaacta ttttatctgg ttgtattgaa gtctttgtaa
    24121 cgccagaatt ggttcaaaaa tacctaccta agcaaaaatg cttgcgcatt ctgtttggaa
    24181 cctttgttgg atttgttttt ccttcttgtg aatgcgggat tattcccatc atcaaccgct
    24241 ttttggaaaa aaaggtgcct agttatacgg ccgtcccttt tctggcaaca gcgcctatta
    24301 ttaatcctat tgttttgttc gctacttatt ctgcttttgg gaattctttg cgctttctga
    24361 tacttcgctt ggtcggtgct gcactagtag ccattacact tggggtaatg ttagctttta
    24421 ttgtagatga taacattctc aaggataatg ctcaacccgt gcattttcat gattattctc
    24481 atgaaagctt gccaaaacgc atttatctag cactggtaca tgctattgat gaattcttcg
    24541 acaccggtag gtatctcgta tttggaacct tgattgcctc tgccatgcaa atatatgtcc
    24601 caactcgtgt gttgacaacg attggacaca atcccttgac agccattttg atcatgatgc
    24661 tgatggcttt cattctatca ttatgtagtg aagccgatgc ctttatcgga gcttccttat
    24721 tatccacctt tggagtggct ccagttcttg cctttctttt aattggtcct atggtggata
    24781 ttaaaaacct tatgatgatg gtaaagactt ttaaaggacg cttcattgtc caatttatcg
    24841 gcgtatccgt tcttatgatt gccgtttatt gtttacttgt gggggtgctc taatgattcg
    24901 ctttttaatt ttagctggct attttgaact aaccatgtat ctccagctgt ctggcaaact
    24961 ggatcagtac atcaatgttc ggtattctta ccttgcttat atttccatgg ttttatcttt
    25021 cattttagct cttgttcaac tctatacctg gatgaaaaac attaaggtac atagccattt
    25081 aaccggaaaa atcgcaaggc tgaccagtcc ttttatcttg gtctttcctg ttttgattgg
    25141 tctccttgtg ccgaccgtaa ccttagattc caccacggtt tctgccaagg gttacacttt
    25201 tcctttggct gcgggagcct ctaaaacggg agtcagtgat gacgggacca ccattcaata
    25261 cctcaaacct gataccagcc tttactttac aaagtctgcc taccaaaagg agatgcgtca
    25321 agaactccat aaatataaag gcaagaaacc ggtcaccatt accactgaaa attatatgga
    25381 agtgatggaa ttgatctatc tctacccaga tgagtttctt gatcgtgaca tccaatacac
    25441 tggctttgtt tataacgaac cgggccatga caactaccaa ttccttttcc gcttcggcat
    25501 tattcactgt attgccgact caggagtgta cggacttttg accacaggta atcaaaccag
    25561 ctaccctaac aacacatggc taacagttaa aggtcgcctt catatggaat atgataaaaa
    25621 cttagaacaa catctacctg tccttcaact tactgaggtt catcaaacca aagagcctaa
    25681 taatccttat gtttaccgcg ttttttaaag actaataaaa aagcacttgt tttttatcaa
    25741 aacaaatgct ttttgagttt tatcagttag cataggaaca gagtcaccat cttaaacaag
    25801 acctatttag gaaaaattat cctcaaggta acgtccattg gtttgaatga cttgtcggta
    25861 ccaatcaaac gattttttct tatagcgtgt gagttgacca gtaccatcat catttcggtc
    25921 aacataaata aaaccgtaac gcttacttaa ttgggctgtt gacatagaga cacaatcaat
    25981 acagccccaa gcagtgtaac ccatgacctc aacgccatct tcaatcgctt tggcaacttg
    26041 cacgagatgc tgactcatgt agtcaatgcg ataatcatcg tgaaccgtca tgctgccatc
    26101 tgcggtttgc accagctgat cctttgcacc taagccattt tcaacaataa acaaaggaat
    26161 ctggtagcgg tcatagtact gattcaagac caatcgcaga ccaattgggt ctatctgcca
    26221 accccactcc gaagattcta aatatggatt ggacaaacca cctagaatat ttccctgacc
    26281 agatgtgtaa gcttcaggat tgtgggcttg tgtgacactc atgtaatagc taaaggatag
    26341 aaaatcaacc gtatgttccg ctaataattc cttgtctccg tcttcaaaaa caatctcaat
    26401 cccattttct ttaaaatacg acttaatata tgaaggatac ttgcctctca catgaatatc
    26461 tgaaaataag agattaagat tttcaaatgc atgcgcagca agtatatcac gaggatcaga
    26521 ggtcattggg taagcaggca tcgccaaaat catacaccca actttaacat caggattgat
    26581 ttcatgcgct agctttgtga cactagcaga tgctaccaat tcatgatgaa tagcttggta
    26641 taaatcttgc aggctcagct tttctttttc tgtcatgatg ccaccactgg taaagggcat
    26701 gtgtaaaatc gagttgactt cgttgaaggt caaccagtat ttgactttgt ccttatagcg
    26761 ttccatgact gtctgagcaa agcgctcaaa aaagccaatc agacgtctat ctgtccaacc
    26821 attataggct ttggccaaat gcagaggtgt ctcataatgc gacaaggtca ctaagggttc
    26881 gataccatag ttcaacaatt catcgaataa gtcatcatag aattgcaaac ctgcttcatt
    26941 gggctggtca tcgtcaccat ttggaaaaat acgagaccaa gcaatagatg ttcgaaagac
    27001 tttaaagtcc atctcggcaa aaagagcaat gtcttctttg tagcggtggt aaaaatcaat
    27061 cgcctctaaa gttaaattat cgctggtagg actatctgtc cattctccta gtccaccatt
    27121 tggtagaaca tcttgtacgg acaaaccttt tgtgtctgcc tcaaatgctc cttccacttg
    27181 gttggcagct actgcgccgc cccataagaa atcttttgga aaaattccca ttctccctct
    27241 ccttttaggt tataaaatga ctaacaaagc gtcctcttta gtcaccattt ttttgtcatc
    27301 ttgaataata atctccaact gctcagccga attggtcacg accacaggac tgatgagtga
    27361 atagcctttt gaagtaatga aatcaatatc catttttaga agtgcctggc ctcgtttcac
    27421 gacatcgcca acagacacta actgctcgaa accttgccct tttaactcaa ccgtatcaat
    27481 accgacatga atcaagactt ccacaccacg tgtgtttttt aaggcaacag catgcttggt
    27541 tggaaagaaa gtgatgactt caccatcaaa gggggcatag accacacctt cgcttggtaa
    27601 tatggcaaat ccttctccta ataacttgga agaaaaggtt tcatcaggaa cttctgatag
    27661 aaaaagcatc tcacctgtca ttggagcata caacgtttgt ttggttgaca agccgctctt
    27721 aacttgtgac atatctgctg caacactcac ttgctttggg gactcttcat caattcccat
    27781 gaaccaagtc aaactgaagg ctaacacaat cgtcgcagct ccggcaatca aagcatttat
    27841 aaaattagct ccgcctgatg ggttgatgta ctgtggtaaa ccaataatag aaggtacgac
    27901 aaaggtataa gaagcaatat tgacaaaacc aataaaggct ccaaccagac cacctgaaat
    27961 catggctgca tagagtggct ttttaaattt cagtgtgacc ccataaagtg ccggttccgt
    28021 gatacctgcc agcaaagctg aaatccccgc ggcaagggca acttgacgtg tttgtttctg
    28081 ctttgtttta aaggcaacag ccaaagatgc ggctccttga gccaaattag aagccaacat
    28141 tgctggtaaa atcaagacat ctggtgttgc gaccgaagcg gccaaaaaga ttggtgcaaa
    28201 agcccagtgc atccccgtca tgacaacaag cggcataatc gctcccaaaa tggcaagtgc
    28261 tagccacgga gccacatgat aaatagcgag catggtatta gataaccctt gaccaataat
    28321 cacaccaaga ggacctacaa ccactaaagc caaaaagcca gaaatcaaaa tgattaaggt
    28381 tggctgtaag aagcttttca tcacgcttgg caccaagcga ttgacccatt tttcaatgta
    28441 ttgcatcaag taaaccatca tcaaaatggg aataacagat gagccatagc tagcaggagt
    28501 gactggtgct ccaaataaag tcaatggttt accttctgct accattgcaa caaaggcagg
    28561 atgcaataaa atccctgcga tcgtcgctgc taaaacaggt gtcaccttaa agcgcgccgc
    28621 tgctgaatag gcaatcatga caggcataaa ataataagcc gcatcgccaa agaagttaat
    28681 aaaggcaacg gtttgagagt ccgcactcgc taagccaagc ataggaagca agattcccac
    28741 cactttgagc attccaccac caagaagggc tggaatcagc ggtgtaatca cgccagcaat
    28801 ggtttcaatc aagcgctcaa ggatacttcc tttcgctttt gaagaatgat cttcatcttg
    28861 attgtcaaaa tgccctaggc ttaaaaaggc ttggtaataa ttattgacat cattgcccaa
    28921 gataatttgg tactggccgt ttttgcgcat cacgccaatc acatttgaaa tggctttgac
    28981 ttgctgatct ttaactttct catcattttt cagtactaag cgtagacgtg ttacacagtg
    29041 tgtcacacgt tgaatatttg ttttgccacc aaccgccgct aaaatagcct tggcagtttc
    29101 ttgatacgtc atattaagtc tcctttaaat gtttcactaa acgtttaaca tgaaccgtca
    29161 aatacaaaag ttcgcttgaa ttaaggtggt agttgtaccg cttttttatc tcctcactaa
    29221 tatctaagac gcaccggtat tctttagggt atttcgtttt caccactaaa agcagttccg
    29281 catcatcatc atcgtaagac atctctgata acacacgttg agcaaataat ttaatatggg
    29341 tcataaagcg gtaataatcg atggatgtgt catccaattc tgttttgaag tctgttttga
    29401 ttttttgctc aatataagaa acaatctccg tcaggcgatg tggctcctta aaaggagtgt
    29461 ccaaactagc attgacaaaa tgcatggcaa taaaagctgc ttcatcaata gctagagtga
    29521 ctcctagatt acgctcaatt agctctaagg cttttacccc tagactatat tcatcaggat
    29581 aatagcgttg aatttcccac cgtagtgggt tatgaatcaa cattccttgc tcatgccttt
    29641 caatagcaga gtgaatatga tccgttaaat taatatagag aatttcatct aaggttttgc
    29701 ctaatttaat tttacctaga ttgataattc tctctgagca agcaacaact tcttgtggca
    29761 ccgtaataaa taactctgtg aagcgattca tattgtcact attttttaaa acaaatgatg
    29821 tttcgatagc attaagctca atactatctc caactttttt tccaaaggca atcccttttc
    29881 ccatcaataa aatatctaat ccttgatggt tggtcgaaat cgccgcatta tggtttaaaa
    29941 cgcgtttaat caacataaaa gtcctagtcc tttagtatca caataaaaaa tgacctatcc
    30001 aaaagctcgc taaaaagcac ttttcgaata ggtccctgct cacaaaactg tgataacatc
    30061 ctttaatatt ctgattgtta tgtctctagc ctgcttactt gaagtaatca catctgagaa
    30121 cgctttaatg ttatcatctc tttaagattc tgtcaagcgt tttcaaaaaa ttctctgaaa
    30181 gagcaactat tgttattcgt atctattgat ttagcaaaaa agagtttctg acaattttaa
    30241 gattatatga tacaataaca atcgattaga taaaggagtt atcatgtcac atcatcaaca
    30301 aaccgtttca aaacaaacaa ttatggcgat tatcgccata gcactcattg gtttttcagg
    30361 aattttgtct gaaaccagta tgaatgtcac cttcccgaca ctgatgtcag tctatcagtt
    30421 acccttaaat agcttgcaat ggatgacgac catttattta ctagcagtgg cgattatgat
    30481 gaccacttcg gctacactga aaaaaaatgt gcgggaaaga cccctctttt ttatggccac
    30541 aggtcttttt acatttggca ccatcttggc cgttctgacc cagtcctttg cgatcatgtt
    30601 gctagcccgc atttttcaag gcattggtac tggtctggta atgcctcaga tgtttaatat
    30661 tattttagag cgtgtcccaa tgcataaggt aggtctattt atgggatttg ctggtcttat
    30721 tattagctta gcacctgctt ttgggcctac ttatgggggc tttatgatta gccattttag
    30781 ttggcaatgg atttttatct gtatactccc tgtaccactg attgcaggta ttctagctta
    30841 ttattacctc gaagattctc cagtaagcga aaaagtaccc tttgactggt tggcatttat
    30901 tgcactatcg attagcttaa cttctgcctt attagctatt actagtctag aaaacggaag
    30961 tgttaatttg tattacttag ggctttttat tctcagcttt gtcctcttcc tctacaagaa
    31021 tctcacagct aagcaaccct ttcttgatat tcgcattctc aaaattccct ctctaacctt
    31081 tggcctgatt cccttttttg tcttccagct gattaattta ggcataaatt ttctaacgcc
    31141 aaactttatt gtcatggaaa agattgctaa tagttctcaa gctggtatgg tgttactacc
    31201 tggtacctta ctcggagctc tactagcacc tgcttttggt aaactttatg atcaaaaagg
    31261 agcaaaactt tcgctttatt taggaaatgc cttatttagt ttatcattga ttattatgac
    31321 acttcaaaca agacatttta tgcttttacc attcactctt ttatatattt tattcacgtt
    31381 tgggcgtaac atgggcttta ataatagctt agccacggct attcgagaat tgcctgccga
    31441 gaaaaatgcc gatgccacgg ccatttttca gatgatgcag caatttgctg gcgctctagg
    31501 aactgctatg gcatcactga tagcaaatag tcaaccagaa ttcacaagcg gtgtccagtc
    31561 tgtctacctt ctctttacta tttttgctct acttgatttt atctttttct ttgctatgtt
    31621 ttaccattta gggaaaaaag gacttgccta agctgactta cttaaaaacc agcctcgttc
    31681 tgttgaacaa gactggtttt tttcttataa aataccttct aaaagacctt tcataaagtc
    31741 ttctgagtgg aattctccaa tatcatccac tttttcacca aatccgatga acttgactgg
    31801 aatgtctaat tcttgacgga tggctaggac tacaccacct ttggccgtgc catcaatttt
    31861 cgttaaaatc aaacctgtta atggtgttat ttttgaaaat tccttggctt ggctaagcgc
    31921 attttgacct gttgacgcat ctaaggccaa aagcgtttca tgaggggcat ctggtagcac
    31981 gcgcttaatg atacgaccca ttttttccag ctctgccatg agattttctt tgttttgcag
    32041 gcgaccagcc gtgtcaatca ggagaatatc tacacctttt gccacagctt tttccatccc
    32101 gtcaaaaaca acagacgctg gatcagcctt ttcagggcca gtaatgactg gcacatctac
    32161 tcggcgtccc cattcgacta gctgagccac agcccctgct cggaaggtat ctgctgccac
    32221 caacatgact tttttacctt cttgtttgta acggtaagcc agcttcccga ttgaagtcgt
    32281 tttaccaacc ccgttaacac ctacaaaaag cataaccgtc aagccatctt gataattaat
    32341 ggcttcatta taacgcccgt ctttttcata gatatctacc aatttttcca caatcacacg
    32401 tttcaaggca tctggttttt tcgcattttc cagtttggct tcataacgca actcctctgt
    32461 caaagttgtc gccacatgta caccgacatc tgataagatc agcatttctt ccaagtcttc
    32521 aaagaattct tcatccactc gcctgaaatt ggcaaagaaa ctgttcagac gagctgagaa
    32581 gccagtccgc gtttttttca agctacgctt gtatttttct tgatctgtct caggaatggt
    32641 atcgtgggtt gccttgtttt gagaagcttc tgctgaggta gaggcctgat tttcttgtgg
    32701 aacttcttct ggcatcactg gaaccgttgc cgctgctttt tcttgaaggc ttttttcaag
    32761 agcagcctta cgacgatagt agtcttccat aacctgttgg ctactggatt gctcttttga
    32821 agtgtctact gcttcttcat tcgccgaatc atttgaggca tcagcttgag cttgttttgt
    32881 tggaaactgt tccacaactg gctggtcaac aaggtctttt ggttctgatg ccgtagattg
    32941 actaagttca cttaccttaa ggtctgtttt gtcggcagca aactcattgg tatcttctga
    33001 tggatgatta ctattgtcac ctgtttcttc ctcaacctgt gcgtttactg aagctgcttc
    33061 gggaccattt tccaccgaac ctgcgccctc tgaagaaacg tcctcttgtt gaaccacctc
    33121 aatcttgttt tgctcgttgg ctttttcaga aagctcctct ttctgagttg tttctgtcaa
    33181 aagattttct tctaactttt cctcagctac cttcggggtt tcttttttcc caaataaacg
    33241 atcaaataat cccattaact ctcctcttct aaaataaatg tcttcacagc ttctgcgact
    33301 ccagactcat cattggttaa ggtggtcacg gcatcggcaa cggctttagc tcctgaaaca
    33361 ccattagcca tagctactcc aagtcctgcc cattctaaca tcgcaaagtc gttagcttcg
    33421 tctcccatag ccatgacatg tctagcgtca aggccaagat gctggcaaag caagtttaat
    33481 ccaaaagctt tatcaatgcc ttttggcatg atttcaaaaa taatatctcg tgatttaaag
    33541 gcttcaaaat cctcaaataa gcttggggat agctttataa tctgctgatc caaaaagtct
    33601 ggatcggtga ctgtcacaat tttgttatag gtaatgtctt ttggtagttc cgctacagat
    33661 gtcacctcaa taaaggtcaa cagtgggtta gctagatggt actgcgaatg cctaccgtcc
    33721 ttacttggaa tgctatacac atccccacca ctgataatat ctgttggtaa gccaaccgcc
    33781 tctaaagctt gctgaatctg gcaaacctgg tcaaaactga gagagctctt atccaaaacc
    33841 tcccctgtat ttcgctgaac caaaccccca ttaaaggtaa tactgtagtc atcgtggtca
    33901 agcaagtcca actcttctag caagttaccg atggccttta gagggcgacc tgtggtaata
    33961 accaccttaa cccctttttc tctagccgct gctaaggctt ttttattggc atctgtgaca
    34021 attttttcag tgttgtagag ggtaccgtct aaatcaagcg ccaaaattct aatattcatg
    34081 agttacacta gtccttttaa atacgttagt actgctccgt cattacagtg gccaatgact
    34141 tggtctgaaa tcactttgat ttcaggtctt gcattttccg tagcaatagc cctaccagca
    34201 aactccaaca tctggtaatc attaaaatta tccccaaaag caatcgtttc tgctttctta
    34261 atgcccaagg cttgacaaag atgctccata ccaaagccct tattcacctc ttttaagata
    34321 atatcaatgg aatcaaagcc ggtggtcact gcagtggcat aagggagggc ttgattcaac
    34381 caatcgcttc cttctaagac ggtatggcct gtgaagttgg tagaaacttt aaaaatggcg
    34441 tcattctcca tatcttcaaa accattaata accttaacat tagcatagta atgttttgtt
    34501 ttttgaatgt actcttctga tgcgcctttt aaaatatagg ctgccttttg cccagaaaaa
    34561 accatacctg tttctacata gtgaggattg gctaaaacct tttttgcaac ttcggtatac
    34621 tgctctttgg tcatcatatc tgcaaataga atctcaccat ggtattgaac cacggaacca
    34681 ttttctgcaa taacagcaat ctgatccaaa aagggctcaa agagctgatc aatggctaag
    34741 agcgagcggc cactcgaaac cgcaaataaa atgccttttt cggctaactt tggcaagagc
    34801 gcagctagtt gctcttgatt ataagtacca tcttcagcta ggaaggtacc atccatatct
    34861 gttgctatta gtttaatcat acaatgtctc ctttttttac tctagggggg tgcaaacgcc
    34921 atttagggtg tgcacttttt aacgatttaa ataagcccca tcatttctgc attctgttca
    34981 atttttctta ttatatcata aaaagcagct ttcattccat tcgtaaaaaa cagccagatt
    35041 atatttcgat aacctgaccg tttttgaagt gaactgctac ttttttattt ttataaatga
    35101 ccactggatg tatactataa aagtagacaa aactttgtgt gttacaatct gttttaaaag
    35161 acacaaaaac gaaaggacaa cctatgtcaa cagttaaacg ctacgatgaa gaattcaaac
    35221 aatctcttgt caacctttat caaactggaa aaactcagtc tgaactctgt aaagactatg
    35281 gggtatccgc ttctgcgctt gcaaaatgga tcaaacagta ttctcaagtc aaactcgaag
    35341 ataattctgt acttactgcc aagcaaatac aagagctaca aaaacgtaat gcgcagcttg
    35401 aagaggagaa ccttatccta aaaaaagcaa gtgccatatt catgcaaaac ttaaagtaag
    35461 actcctcgct gtctatcggt tacgctttga acacgacaca acaaccttat gtcgtgtttt
    35521 acgtgtcaat cgctccactt actataaatt tctaaaacat aagccctcaa aaagagaatt
    35581 ggataatcaa atttatagaa aacaaatact tgagatttat accaaagcaa acaaaagact
    35641 tggtgtgaag tctatcaagg tcattcttca aagagactac gacacaaaaa tctctgaagg
    35701 aagaatttac cgtcttatga agaatatggc gctccctaaa atggctaccg ttaagccaaa
    35761 aacagctctt aaaaggactc aaaaaacgta tcctcaaaac ttactcaacc agaaatttaa
    35821 tcctgacaaa ccaaatcaag tatggtctac tgacttcacc tatatttcta ttggatataa
    35881 gaaatatgtc tatctctgcg caatacttga tctctattct agaaaatgta ttgcttggaa
    35941 actgagtcat catatggatg caaagttagc atgtgacact ctagaattag ctcttaataa
    36001 aagaaagatt gaaggaacac ttctctttca ttccgaccaa gggtcacaat ttaaggccag
    36061 gaaattgaga aaaataattg atgacaacac tatcatgcat tctttttcta aacctggata
    36121 tccttatgat aatgccgtaa ctgaagcatt tttcaagtat ttaaagcata gacaaatcaa
    36181 ccgaaaaaag tatcaaaata tcaaacaggt tcaattagac tgctttgaat acattgagaa
    36241 tttttataac aattacaacc cacatacggc taatctagga ctaaccccta atcagaaaga
    36301 agaaaattag tttaacgtaa taaaataaca cggttttctg tctacttatt tgacattagt
    36361 ccaaaataca tcctaatggt gtcgtttttt ttatttcact agacattcgt tctagtttag
    36421 gatataagaa ggtctcaaat ttttttcatg atgtttattc caaacatcca atcacctttc
    36481 tatataactg ttcatttagt ggtatagaca aacagaaata ctccgtttct agtttcatag
    36541 aagacggagt attttttagt agagacgtct ggattgatag atagttggta tatagctcat
    36601 ccctactagg ctttcattat agactatggt gggtttcgtt gacaacaata tgtgattatt
    36661 attctaaatg acagtataca tcaactatca agtatgcttt taattttatt ttttaaagct
    36721 acagatgaaa atctgtattc catacttcca tctaatcgaa caataatata atgatgtctc
    36781 gaatataatt catgttaaaa aaactttgat acccacttaa tttatttgct aattcaagac
    36841 aattcttata gattttcaca tctatttttt caactaatat cattattcta tcttcaattt
    36901 catactcaat ctcttgtgat aaaacagtgg ttcctattcc catgcaaact cctaatacgt
    36961 ttactttatt aaatttagaa accatatcat caattctacc accatcagca atatcaaata
    37021 tgtcacctga cttagttcgt atgaagattt tatagttcat acttgaataa tgtcctgttc
    37081 catataaatt agataatgaa aagtaaatgc aatctgctgg taaaaagttt tttacatact
    37141 cgtacaagac taaaactttt ataaattcct gtttcaccag tttgttactt atttttgaaa
    37201 taagactaat taagagttcc atatttattt tgtctttttc ataaagatat tttatgattt
    37261 ctatgtcatt attacacaaa tatttaccca atattgcttc aattgaaata tcttcaaatc
    37321 ttaacttttt agataaatct ttctccaaaa catcaaatat atttttgtta gacagttgaa
    37381 taaattctac tttaattcct ttaaactcat ccacattctc gccactagtc gtgcgaccaa
    37441 agaggtagaa aaagtcctga ccttcataac tgttttgagg cttatctcta gccctttttc
    37501 ttccaattaa atcaagtagt cccataagcc ctccttattt tggggtacaa aaaaagcacc
    37561 tcctttgaag tgctttcggt atatttcttt caaagtaatc aacagtcttt cttacaaaac
    37621 ctagtattct cattctgtca attccttaaa tgcgtcaaga tgtcgtgata atactgaagt
    37681 cgcaatctca tctaaccttg cttgttcaac aactgttgtc atctgctcat cactgcttaa
    37741 actttggtga tccgctgata gtttgctatc agatggactt aataccaaag ttccatcagt
    37801 tgatttataa aggttaaact cctaattctc ttgaatgcca aatgggtcag gtatcggaag
    37861 atagatgtca tcaccaattt gtatcgtctt tacgagttcc atacatcact ctcccttact
    37921 ttaccaatta ttcatatgac gtgatccata gacgaccgca acaattataa cttcatcttc
    37981 cagaacatgg tatacaatgc gatatttttt gacaatcagt tgtctgaagg tatagccttt
    38041 tccaatcaga tcctcaatga tggcacaacg ttcaggaaaa atggatagtg ataacatttc
    38101 ttgggataac ctctcaagaa gattatccgc tgcctgtggt gcacagagtt catcacgaac
    38161 atagtgatag atgctcagca aatctgcttt agcatcatcc gacatggtga cctgatattc
    38221 tttcattaag cattttcctt caattgagat agaaattctc tgacatcctt gcggttgcca
    38281 gttttcgcat cttcaaagct gaagataagc ttatcataaa acttctcctg actcatgtaa
    38341 tcaacattaa ctcgttgagg cgcttcaggt agagaaacat caaatgggat acccccagtc
    38401 aaaataatct gattcaaaaa catatcaatc gcagttgaca taggaatacc taagcgtttc
    38461 aaaatatcat ctgccgcact ttttactgaa tcatcaactc gtaaattcaa agttcccgtt
    38521 ttagccatgg ttatcctcct tttttgtaac gacattgtat cacgttttta gagttgactc
    38581 aactaaaaac tcaatatccc tcgctcatca tagacgctag cttcatcacc ttggcggcga
    38641 atgcaacggt caagccccag gataagacct acaataccgt caatcttctc aacagatttt
    38701 tccttatctg gcttgatgtt gcctccaggg gcttgtcgca tcaccacgtt ttgtcccatc
    38761 catttaagga ctggatgacc accatgttag attttccctt ccatcatgag tttatagagt
    38821 tccttggacg gtggactcat atccttataa ctctgctcaa aaggcaccat ggtcaagccg
    38881 acaccgcaat tccaaggtat cttctagtaa ccataagaga gaagacaggg attgtaaaat
    38941 caaccactgt gcaaaatact gcgttcacta cccagtcgaa tcagctcaaa aaacaatacg
    39001 ggcagttctt gttaacagaa tctaataact gttgtgcatg cccaggctgt gatagaccac
    39061 tcattctaac cagtggcaac ttagcagcag aaaattacga ggtttcagcc attgaaaaag
    39121 ataaggacgc tgaaccactg aatctgatag ccctctgccc agattgtttt ttaacctatc
    39181 aagcagatag tcgcaaaaaa attgtaacag ctctaaaaaa tgttaaaaag attctagtct
    39241 ctgcacataa cagccaacaa gcgatttctg atatgaagtt agacagtgga attgtttcag
    39301 ttttgactag tctcaataaa ctaaaatgtg atgaatatga tatctcctat gactcgaagc
    39361 aattgactga taagatatca cctgagaaca atcgtacgct ttatcaattg gttaaaaacc
    39421 cagttattga taactactta accattcaaa aaatcatcgt aaatttggac aaacaaggaa
    39481 aaattgatta cgaggaaatc caatatcaaa cgcgatcgat gtataaaaag ttaaaagcag
    39541 ccaagcataa taatctggct attttcaata ctatttcgga aaaactccat aaagctacac
    39601 tacaggacat ctacttctgt cagacgattg tctcttactt tatccaaaaa tgcgaggtac
    39661 ttgaataatg caattaccaa ataaacttta ctcctatcaa aaaagcaccc ttgcttattt
    39721 gcctagagtg ctaaatgaaa tcaaaagtgg aaactcaaac gtcaaagata tctttcacgc
    39781 tatctcagaa gagttggatg atcctacaga tttcttatct ataatggatt gcttgtatgc
    39841 attgaacgct attgaaatgt ctaatgaagg agaagtaaaa ttatgcttat agaaatgtgg
    39901 tctccagtat ttaagaatca cggagaaatt cgggaatcaa tctgcttcca ctatgggtta
    39961 aacgtgatta tggggatgga tttagctgat aactctatcg gcaaatcctc ctcactatta
    40021 gccattgatt tcatctttgg aggtaatagc tatctaaaat caattgcggt taaaaaatta
    40081 ggtgatcatc ctatctattt ctgctttcaa tttgagaaaa agttttattt ttcaagagat
    40141 acggccaacc cagatatcat tctagtgtgt gacaagagct actctccaac cggtgaaaca
    40201 atggacctag gaatttttct taacaaactt aagaaacgat atcatttaga ttctccagag
    40261 ctatcattcc gattagctat gagtggcttc tttaggattg caggaaaaag taatcaaaat
    40321 accgatttcc ctttacaagt ttattcgagc caaaaatctt ctgaatctat tactactctc
    40381 atccaactgt ttaatttgta tgataacatt gcacgataca aagaacgtct gaaagataag
    40441 agcgaccagt taacaacttt tcgtaatgct cgaaagtata ccttcatctc caacctggtt
    40501 ggcggtaaaa agcaatttga agcaaatgtc tcagaaataa aaagattgga atatgattta
    40561 gcacatctcc aagacactca tcaagataaa attgactctg atgatattga gaaaaatcaa
    40621 caaaaactcc agcttagaaa tactaagctg gagttagaaa gcagtcttcg ggacaagcaa
    40681 agacgtctta agctattgga catcagtatc gaatttggct tatatcctac tgaatctgac
    40741 ttaacagagc ttcaacaata cttcccagat actaatctca aaaaattata tgaagttgaa
    40801 gcttaccaca aaaaattgga aactatttta gattccgaat tctcaactga acgtgaatcc
    40861 ctaatagctg agatcgacga attagagagt caattaacaa ctctaaacca agaacttcaa
    40921 gaactaggaa acatcccaaa tctttcaagt gagtacttag aaagctactc taaactaaca
    40981 gctacaatca atgcactaaa agaacaaaac gaggcctact taaaggagtc tggtctatcc
    41041 aaagaaaaat cagaagcgga cgctgacttg aaacgcagta cagaagatat ccttctagat
    41101 ctagaagtaa aaatcaacag taagatgcgt gaattcaata acattctata tccagatatt
    41161 cgcaaagctc ctcaaattaa cctcaatgct cacaatagct actccttcta tacaccagat
    41221 gatgatggta caggaactaa gtttaaaggg atgattgtat tcgacttagt aatgctctac
    41281 cttactaatc tgccagcact cacacacgat tcattactct tgagtaatgt tagctaccaa
    41341 gcgactgaag cacttttgaa gctgtatgac cagtcaaggt cattgaacaa acaagtcttt
    41401 ttagccttcg ataaagccag ctcttattct ccagatgcta atcaactctt gtcagaaaat
    41461 acggtattga gactctctag taacggaaat gaactctacg gtatttcatg gaacaaagga
    41521 gaaaactcag atgagattta gttacaataa attatggaaa cttcttattg ataaaggttg
    41581 gaccaaaaca aagctcaggc aagaagctgg gattagttct tccacgatcg caaaattggg
    41641 aaaaggggaa aatatcacta ctgatatttt attggaaatt tgtattgcac ttgattgtaa
    41701 gattgaagat atagtagaaa ttgtagataa taatatctag aaataaaaaa agcactaagt
    41761 tg
//
LOCUS       DATWVB010000014        41501 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.014, whole genome shotgun sequence.
ACCESSION   DATWVB010000014 DATWVB010000000
VERSION     DATWVB010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41501
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.014"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..227)
                     /locus_tag="VCX65_000824"
     CDS             complement(<1..227)
                     /locus_tag="VCX65_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEP5053297.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKKILVDSVCLEDKIKHLINDPKC"
     gene            complement(296..367)
                     /gene="shp3"
                     /locus_tag="VCX65_000825"
     CDS             complement(296..367)
                     /gene="shp3"
                     /locus_tag="VCX65_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEP5053298.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            447..1298
                     /gene="rgg3"
                     /locus_tag="VCX65_000826"
     CDS             447..1298
                     /gene="rgg3"
                     /locus_tag="VCX65_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HEP5053299.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     SLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(1551..5090)
                     /gene="smc"
                     /locus_tag="VCX65_000827"
     CDS             complement(1551..5090)
                     /gene="smc"
                     /locus_tag="VCX65_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEP5053300.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFYKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKRVQELERDYQLKQERLFDLLNQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEIALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLVRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGTNRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKSALTCDIDDIKENKDLVR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAINQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIRKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(5091..5783)
                     /locus_tag="VCX65_000828"
     CDS             complement(5091..5783)
                     /locus_tag="VCX65_000828"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEP5053301.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVRD
                     YKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGVVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(6216..7025)
                     /locus_tag="VCX65_000829"
     CDS             complement(6216..7025)
                     /locus_tag="VCX65_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEP5053302.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(7029..8381)
                     /gene="vicK"
                     /locus_tag="VCX65_000830"
     CDS             complement(7029..8381)
                     /gene="vicK"
                     /locus_tag="VCX65_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEP5053303.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWIEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(8374..9084)
                     /locus_tag="VCX65_000831"
     CDS             complement(8374..9084)
                     /locus_tag="VCX65_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5053304.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(9246..10280)
                     /locus_tag="VCX65_000832"
     CDS             complement(9246..10280)
                     /locus_tag="VCX65_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEP5053305.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     PIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFILDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISRHDP
                     QFRRDTLKGFRSPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(10336..11583)
                     /locus_tag="VCX65_000833"
     CDS             complement(10336..11583)
                     /locus_tag="VCX65_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEP5053306.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDSELLKKADFAVL
                     SSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLKDNGKINREVLLNKIPKQWLS"
     gene            complement(11540..12688)
                     /locus_tag="VCX65_000834"
     CDS             complement(11540..12688)
                     /locus_tag="VCX65_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEP5053307.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNAVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFT
                     KEYLNHWTLRSHQKASYCQEQALLADLILDLPGASDQGIRPRLSSKVLSKVPPILGED
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVIKASQVLLEKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGRYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(13083..13232)
                     /locus_tag="VCX65_000835"
     CDS             complement(13083..13232)
                     /locus_tag="VCX65_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HEP5053308.1"
                     /translation="MQLLDNVYGTLRSFAFMRPVKSSNDTSLADALQADTDMAFILVR
                     GINYQ"
     gene            complement(13318..14103)
                     /locus_tag="VCX65_000836"
     CDS             complement(13318..14103)
                     /locus_tag="VCX65_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053309.1"
                     /translation="MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFVIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLDAYESAGS"
     gene            complement(14105..14923)
                     /locus_tag="VCX65_000837"
     CDS             complement(14105..14923)
                     /locus_tag="VCX65_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEP5053310.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLMVLSGIKVMAGLSTLQVLASSCLYLVSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKVVYIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(14925..15917)
                     /locus_tag="VCX65_000838"
     CDS             complement(14925..15917)
                     /locus_tag="VCX65_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP5053311.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEKTTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQSFGKMKSLSFELKPGQEQVVSQFMGLPDIT
                     VERHELSLDIQYDSSRYQTADIIQKTMADFAVRDLKMTDVDIEDIVRRFYRKEL"
     gene            complement(16058..18001)
                     /gene="thrS"
                     /locus_tag="VCX65_000839"
     CDS             complement(16058..18001)
                     /gene="thrS"
                     /locus_tag="VCX65_000839"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEP5053312.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTRKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTE
                     SVEEFVENILADIARKSCPDAQA"
     gene            complement(18423..19757)
                     /locus_tag="VCX65_000840"
     CDS             complement(18423..19757)
                     /locus_tag="VCX65_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEP5053313.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLS
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(19759..20757)
                     /locus_tag="VCX65_000841"
     CDS             complement(19759..20757)
                     /locus_tag="VCX65_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEP5053314.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADSKKEAAFRRYFDIKEG
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(20888..21889)
                     /gene="ccpA"
                     /locus_tag="VCX65_000842"
     CDS             complement(20888..21889)
                     /gene="ccpA"
                     /locus_tag="VCX65_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEP5053315.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            22063..23148
                     /locus_tag="VCX65_000843"
     CDS             22063..23148
                     /locus_tag="VCX65_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEP5053316.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYVEFD
                     HLNVNKFHGLQTIFSGQFNNLTPYVQGMRLVKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            23197..23862
                     /locus_tag="VCX65_000844"
     CDS             23197..23862
                     /locus_tag="VCX65_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEP5053317.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SVGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            23873..24250
                     /locus_tag="VCX65_000845"
     CDS             23873..24250
                     /locus_tag="VCX65_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEP5053318.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            24395..25321
                     /locus_tag="VCX65_000846"
     CDS             24395..25321
                     /locus_tag="VCX65_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEP5053319.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPVMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            25532..26215
                     /locus_tag="VCX65_000847"
     CDS             25532..26215
                     /locus_tag="VCX65_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEP5053320.1"
                     /translation="MEWIKLIGIVIIVLGFILKFDAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQALTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDAEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            26215..27141
                     /locus_tag="VCX65_000848"
     CDS             26215..27141
                     /locus_tag="VCX65_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEP5053321.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIISHIALMYLLAYY"
     gene            27191..27838
                     /gene="pcp"
                     /locus_tag="VCX65_000849"
     CDS             27191..27838
                     /gene="pcp"
                     /locus_tag="VCX65_000849"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEP5053322.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(27955..28674)
                     /locus_tag="VCX65_000850"
     CDS             complement(27955..28674)
                     /locus_tag="VCX65_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HEP5053323.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(28680..29147)
                     /gene="smpB"
                     /locus_tag="VCX65_000851"
     CDS             complement(28680..29147)
                     /gene="smpB"
                     /locus_tag="VCX65_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEP5053324.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            complement(29150..31483)
                     /gene="rnr"
                     /locus_tag="VCX65_000852"
     CDS             complement(29150..31483)
                     /gene="rnr"
                     /locus_tag="VCX65_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEP5053325.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSALDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNVDRLTQSALMEINSQGHVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVALHRILEAMRSKRGALNFDTQEAKVIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKAEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYSQPSQEKRDHFTQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVASVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGTK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(31577..31813)
                     /gene="secG"
                     /locus_tag="VCX65_000853"
     CDS             complement(31577..31813)
                     /gene="secG"
                     /locus_tag="VCX65_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEP5053326.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(31859..32005)
                     /gene="rpmG"
                     /locus_tag="VCX65_000854"
     CDS             complement(31859..32005)
                     /gene="rpmG"
                     /locus_tag="VCX65_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEP5053327.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(32002..33195)
                     /locus_tag="VCX65_000855"
     CDS             complement(32002..33195)
                     /locus_tag="VCX65_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEP5053328.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPKELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPIRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVAPILSLYIRHLGQTHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(33317..34819)
                     /locus_tag="VCX65_000856"
     CDS             complement(33317..34819)
                     /locus_tag="VCX65_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HEP5053329.1"
                     /translation="MTTMTIAKGSQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISEMGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DHASDYSSHYGNIAKQSIGTIQRSLLTLEQEGAHQFFGEPALDVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYELLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLAQLGNRIQHALRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSEI
                     ESQQLVQSSPFASKYSQSIDRESAYEKLAAKVLEDNRLAQEAIATAKREKEAKEAIKA
                     QAATKKASRRSVGRPRKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR"
     gene            complement(35009..35602)
                     /locus_tag="VCX65_000857"
     CDS             complement(35009..35602)
                     /locus_tag="VCX65_000857"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEP5053330.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLA
                     QSQAIFFMDIPILMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNSGDIAALIKQVQSALLSLANPR"
     gene            complement(35599..36426)
                     /gene="mutM"
                     /locus_tag="VCX65_000858"
     CDS             complement(35599..36426)
                     /gene="mutM"
                     /locus_tag="VCX65_000858"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEP5053331.1"
                     /translation="MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPGTASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP"
     gene            complement(36598..37464)
                     /gene="rgg2"
                     /locus_tag="VCX65_000859"
     CDS             complement(36598..37464)
                     /gene="rgg2"
                     /locus_tag="VCX65_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HEP5053332.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            37553..37621
                     /gene="shp2"
                     /locus_tag="VCX65_000860"
     CDS             37553..37621
                     /gene="shp2"
                     /locus_tag="VCX65_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HEP5053333.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            38535..38804
                     /gene="stcA"
                     /locus_tag="VCX65_000861"
     CDS             38535..38804
                     /gene="stcA"
                     /locus_tag="VCX65_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HEP5053334.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIERKRTAMTIGHS
                     KQTPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQY"
     gene            complement(39152..39550)
                     /locus_tag="VCX65_000862"
     CDS             complement(39152..39550)
                     /locus_tag="VCX65_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEP5053335.1"
                     /translation="MHRLPNRLIPEEDNNKLSRVAKEVVTEPRLNNPFLLPKKVLSLE
                     DDAAILNHLEEDRNVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTG
                     ITYGDDTLADLTHHLLHSDGVIPSLNDKSA"
     gene            complement(39647..40717)
                     /locus_tag="VCX65_000863"
     CDS             complement(39647..40717)
                     /locus_tag="VCX65_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053336.1"
                     /translation="MMMLRDVKVKMSSLLVGCAATLLVSLSSTVAADSVHSSDRRFGV
                     GYKEETTSQFSSDQPSQVVLYRGEANTVRFTYTNQMYLMKDIRIALDGSGKSLTAQTV
                     PGMGHVYEGFQTSARGIFTMSGVPESTVPVANPNVQTKYTRYFKVIDDMHNTMYKGTV
                     FLVQPQAWKYTMKSVDQLPVDDLNHIGVAGIERMTTLIKNAGALLTTGSSGAFPDNIK
                     VSINPRGGQATIIYGDGSTDIIPSAVLWEKGSVKEPTEADQSVGTPTPGIPGKFKRDQ
                     SLNEHEAMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNEDEKEKPASDVKVRPAEVG
                     SWLEPATALPSVEMSAEDRLKS"
     gene            complement(40968..41369)
                     /locus_tag="VCX65_000864"
     CDS             complement(40968..41369)
                     /locus_tag="VCX65_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053337.1"
                     /translation="MRNILRFLGIVIISAVILFSIGSFYDLPLMKNIQLICWSFILDL
                     FVFVYKQRQTTEVLTWYQVVKQFWLFIKCTILIPTLIAFIIIIGCLTSISEVSIYFYL
                     HLTVVCYTIGMILSLGRLIFPNHSIFNKLKK"
BASE COUNT        12543 a         8807 c         7241 g        12910 t
ORIGIN      
        1 atacattttg gatcatttat cagatgtttg attttatctt ctaaacacac tgagtctacc
       61 aaaatttttt tatgtttata ttcatccaga actcctatgt tgtgatttag atattcaaat
      121 aattcatctg atatagaatg ttcaactgga ttaccaagca atgcagaata cataaatttc
      181 atcctcctac gtttaattag tttactacta acataaagta caagcattac acagagctaa
      241 ccattaccta taagtcttta gagtatctaa agacttaggt gtacacctaa gtaacttacc
      301 caccaacaat aatgataata tccattgcta aaattaaaat cggcaaaaat tttgaaattt
      361 tcttcataag cggacttcct ttcagttttt atttattgta caataaaaaa aaacggaatt
      421 gatttttgtt gggaaagtgg gaaaatatga aatcaaaact tggtgccaca cttagaaaag
      481 ttcgaaaagg aaagcaaatt agtctgtgct tcgtggcaga tgaacacctt tcaaaatcac
      541 aaatctctcg ttttgagcgc ggggagtcag agatatcgtg tatccgactg atcaatattc
      601 tagacaaatt acacattact ttggatgagt ttcttatttt acatgatgaa gactatacca
      661 attccgaaac atttgctaac ctggtacagt atattcgtaa gcaatattca tcacaaaata
      721 tcaataatat agcatgttta ctttccgaca cttctgatta cactctgaat tcttttgaga
      781 aaacaatggt aaagtccatt ttacacacaa tggattcaag catcattcca tcagatgatg
      841 aattacttca actaacagat tatctcttta aagttgaaaa atggggctac tatgaaatcc
      901 ttttgttggg taactgtgta cgaacaatta actacaactc ctacttccta ttgacaaagg
      961 agatgttaaa taattacatt tactcttcac ggaacaaaac taataaacga attgtcactc
     1021 agcttgctat aaattgtttc attcttagta tcaataagga ggaattttct aattgctcct
     1081 atttaattga tgagataaaa tcattattag ataatgaatt aaacttctat gaacagacag
     1141 tttttctcta tgcaacaggt tactttgaat ttaagcgcca attagaaact ggagttgaaa
     1201 agatgaaaca agccatacaa gttcttgata ttttaaatga agacaagtta aaattacatt
     1261 acgctgacca ttttgataaa ctagtcaaca aagattaagt gaaatcattc tttacctttt
     1321 aacgaaatgc caatcaagag tgtctcaata aaaaatcatc tactctgaca acttttctct
     1381 tttacctatc gacagctaaa aagccttgga aactgctatt tccaaggctt tctttgtact
     1441 ctattgtatc aattagctta ttccgatttc tgttgctatt agtttaatca tgaaatctcc
     1501 taacttatga ccgaacatcc aaaaaaacag aaggaactcc cttctgtttt ttaattggtc
     1561 atctcttgag cttcttttaa ttttacagat acaattttag agacccccga ttcctgcatg
     1621 gtaattccat aaatactatc tgctgcagcc attgttcctt tacgatgggt cacgacaata
     1681 aattgactat ctttgtcaaa gcgattgagg aaatccccaa agcgcttaac atttgcttca
     1741 tcaagagccg cttctacctc atctaaaatc acaaacggaa tcgttttaac acgtataata
     1801 gcaaacaata aagccagtgc tgacaaagct ttctctccgc ctgacatcaa gttaagagat
     1861 tggattttct taccaggagg ctgcacagaa atctctatac cagcagacaa gagatctgtt
     1921 tccgttaaaa ccaaatcagc agaaccccca ccaaacatct gagtaaaggt ttccttaaaa
     1981 ctttttcgaa ttgcctcaaa agtcactttg aaacgagcct tcacttcgct atccatacta
     2041 ttaatagtct ctagcaaaag atttttagct tttgtcagat ctgtcttttg acttgttaaa
     2101 aaagtcaaac gctcatgcac ttcctcatac tgattaatag catcactatt aattggtcct
     2161 agtgcacgaa tagtcttttg taaatggtgt aatttttctt tggcactttc taagtgatca
     2221 atactatttg ttacctcctt tgcgtctgct agtgtcattt gaaaatcttc tgataaactt
     2281 ttagcatagg ctcgtaagcg attagccact tgctctaaat gtgtctctaa cttggtttga
     2341 cgacgaataa atgtgtcatt tttttcgctt tctttggtta ttttttctgc tgtttcttct
     2401 aagcgggcct catagtcctc tatttcaaat cttaattgga ctaaacgttt ttgagcacca
     2461 gacttatgct ctgtggcatc ttgtaactgt ttttgccact ggggtagtct ttgaatgctg
     2521 tcttgactta cgttgttgtt tagtatgctt tcaagtttga gaatattttg ctggcattgc
     2581 ttcagctgag ttcttagacg agattgatta gcttgctcaa atttcttttc attaagtaaa
     2641 tctctttctt gcaaacgagc ttgagataaa gcttggtgaa tgttttgtgt tttttgccta
     2701 accaaatctt tgttttcttt gatatcatca atatcacaag ttaaggcact ttttttctta
     2761 gcaatagctg ttaatgcttc ttcaatacga gcttgctctg ccaataaaga ttcatcagaa
     2821 tgagtcgtct gactttgatc aagggcagct aacaaagcct ttgaatcttc ttgtttttct
     2881 tgcaattgct gataagccat ttgagctctt tgttcagcta agcgtgcctg gtcaccggct
     2941 aatttcaatt gtgtcagttc ttcttttttt gctatcaaat cgctttgcaa ggcagctact
     3001 tctttttcag ttatttttaa ttgctcaact aatcgcgtta attcctcact gatttgttct
     3061 aactctggtt tgataaaagt tgtattgctt tgtctattag ttcctcctga aaaagaacca
     3121 cctggtcgta attctgttcc atcaagagta acaattctta ccttatatcc taataagcgc
     3181 gctgcaatat tagcttgatc aatagtttca aagatagcag tactagataa aaggttttgg
     3241 ataatagctg aaagactatc atcatagcga accaatgatt ctgcagttcc cagataacct
     3301 tcacaagtcg ctaattgacg atgatagtgt tctgataatg atctagcctt tatagtagtt
     3361 aaaggtaaaa aagttgctcg tccttggcga ttttttttca aataagcaat tgctcttttt
     3421 gctgcagctt cgtctgttac aataatatgc tgactattag cacctaatgc aatttcaaga
     3481 gctgtttggt aatcagaatc aaaagaaagg tgttcactga ctgcacctat gatccctcca
     3541 agcttttttt gtgattgaag gacagctcgt actcccgcat agaattgact atgacttttt
     3601 tgaatagatt ctaagctagc cttacgagct tcttttcctt ttttttgatt caacaagtca
     3661 aatagtcttt cttgcttcag ttggtaatct ctttctaatt cctgaacgcg tttatcacct
     3721 tcttgataat tttggagcaa catttcgact tgctcttttt gagctttata atgagcttga
     3781 gctttttgag actcgtcatt aagttgatca agcttagtaa caagcagctg atattcttga
     3841 gccttatgtt gacgagcctg tttttctttg tctaaatggg cttttaaagc tgtcagctga
     3901 tttgataagg ccgcctcttt ttgcatcaat aatacaaact cttctcttag agtttccatt
     3961 aattggtcgg gatcacttga aaaacgctct aatgcattgc tcaattcgtt taactgttgt
     4021 ttgacatcac aaagttgttg atcaatatgc aataattgtt ctgtacgctg cttttcttct
     4081 gcttgaaaac catccaattg ttcttgtaac tgttcgaggt gttttttggc ttctgccttt
     4141 ttctctgctt cttggccact ttctagctta accaattcaa tttgcttttc caagtcagct
     4201 attagcttgg ttaattctaa taatgttgtt tgggtttgat ctgactcttg actaagaacc
     4261 tgcttttttt gcttgaattt ttggtaatct tcttccatag attgacgctt agcgtaataa
     4321 gatgctaagt cttgttgtaa agcagctaaa gcttcagtat ctttagtctg tctttcttga
     4381 gctatatcaa tatctttgac tagaatatct agttgtagtt gcttacgatt ggcatcaagt
     4441 tctaaaaatt gtttagctac tttagcttgc ttttcaagtg gggccaactg cgtgtctagc
     4501 tcataaataa tatcctctag acggtctaaa ttatcttgag tttgatttaa tttaatctga
     4561 gtttcttttt tacgtgtttt atattttaaa acaccagctg cttcttcaaa aatggcgcgc
     4621 ctttcttcag gtttactatt gaaaatttcc tctacgcgac cttgagaaat aatggagaaa
     4681 gaatcacgac caagccctgt atccataaac aaatcatgaa tatcacggag ccttaccttg
     4741 cgaccatcaa tcagatagtc actatctcca tttcggtaaa tatgcctttc gacacggatt
     4801 tctttcttgg cagtttttat aaaatgatcg gaattatcaa gaacaaccgc taccttagca
     4861 tagtttagag gattacggtt ttgtgtccca gcaaaaatga catctggcat cttgccccca
     4921 cgcagatttt tagcacttga ttctcctaaa gcccaacgta aactttctgt aatattactt
     4981 ttacctgaac catttggtcc tacgactgca gttactccct tataaaattc aattttagtc
     5041 ttgtccgcaa aggacttgaa cccttccaac tcaatttctt ttaaaaacat ctaaacctca
     5101 ctaagttggg caagggcatt tttagcagca tcttgctccg ctaatttttt agacttacct
     5161 aaacctttac taaggacaac accattaaca actatcgata cctcaaattg tttagcgtgg
     5221 gcaggtcctt tctcactaat gacttgataa tcaatagcca catcaccttt tgtttgcaaa
     5281 aactcttgaa gacaagtttt atagtctcta accctttcaa aattcccttt ttccacctga
     5341 gggatcatga cttgtttcaa gaagcgacgt actgcatcaa tccccttatc taataaaaga
     5401 gcacctaaaa aggcttcaaa taagtctcct aaaatagtat cacgacggcg accacctgac
     5461 ttttcctcac cttttcctag tttgatataa gcgtcaaaag aacaaaatcg tgaaaaacct
     5521 gccaagcttt cctcacgtac aatcatggaa cgtaacttag acatatctcc ttctgtcttt
     5581 ttaggatact ttgcaaataa atactctgaa ataatcaatt gtagaacagc gtctcctaaa
     5641 aattccaagc gttcattatg tgaaacgttt aggagacgat gctcgttagc gtaagaggtg
     5701 tgggtaaaag ctgtttctag taaagtcaaa tcattaaatt gaatatcaaa agatgttgag
     5761 agtaactctt caagctgttt cataaaaaat ccctttcata tttgtcagta gaccttattt
     5821 agtataccaa aaatccacct agaaaaccga ctctaagtgg atttttcgtg atttattaaa
     5881 catcttaaat acccgtcaaa ggaaactttc tcatacaatc aaaagactct acactatctg
     5941 aggggaattt cccactacag atagtataga gctattttgt ttttagtctg aacaactaaa
     6001 aaactacctt atctttataa tcctcaacac ctttgataaa tagatcagac aagccaaaac
     6061 tacaggctaa tttaagtcta ttgatgctct aaaggatgac caatgagagt tcattgaact
     6121 cagaagacaa tacgctttaa gacatcaaaa aaatagccct gactggtata tcaccaatca
     6181 gcgctacttt gcatattctc ttttagtttc ttatctcaaa tatcagttaa tggacaagca
     6241 gtatctggag aggtatcatg gaccgtaaag tctgtaccta ctgctaaatc tgccatagcc
     6301 agttgattga ccatcgtcat atgcgctaac tctttgatgt tattttcttt actcagatga
     6361 cctaggtata tttttttggt attgtacccc aggcttctaa tcatggctcc cgctccatct
     6421 tcatttgata aatgtcctaa atcagataaa atacgctgct tcaagctcca aggataagag
     6481 cctgatctca aaatttcaat atcatgattg gattcaatca agtagccatc tgcattttca
     6541 ataatacctg tcatcctatc actgacatat cctgtatctg tcaacatcac aaaagactta
     6601 ttatctttca taatccgata aaattgagga tcaatagcgt catggctgac tccaaaactt
     6661 tcgatatcaa catctccaaa ggtcaaaact ttatcccttt ggaaaatatg tttttgtgag
     6721 gcatcaagct tacctagcat attgcactca tccatcagct gccatgtttt ttcattagca
     6781 tagatatcca aatggtattt gcgggccata acgcctacac ccttaatatg gtcagagtgc
     6841 tcatgggtaa tcaaaatagc atccaaatcc tcaggtttgc ggtcaatttc agcaagaaga
     6901 ctggtaattt tcttaccagt aagccctgca tcaatcaata agcgtttttt aggtgtttct
     6961 aaataaaaac aatttcctgt ggacccagat gctaaaatac tatatttaaa accactctca
     7021 ttcattgatt agtctacatc ttcctcccat tcttcataga tggctgcatc tttttcataa
     7081 ggcaagacaa tagtaaaggt cgatccttta ccatagtcac tcttagccca gataaagcca
     7141 tggtgctgct tgatgatttc tttagcaatg gcaaggccta gaccggtccc tccttgggca
     7201 cgacttcttg ccttgtctac acgatagaac cgatcaaaaa taagaggcaa atctgtttta
     7261 gggataccta gtccttggtc tgaaatggaa ataattaatt gggtatctgt tgttttcata
     7321 cggactgtga tttttccacc atctggagaa tacttaatgg cattgttcaa aatattctcg
     7381 ataacctgtg tcattttatc attatcaatt tcaatccaga cagaggtaat agggtaatct
     7441 cttacaattt catagacttt tcctgtacct gtatgctgat ttttaaccaa atcaaatctg
     7501 tttaaaatag aagttataaa agcagtaaaa ttagtcatct ctactgctaa ttgggttact
     7561 tgattatcaa tccgagacag gtttaaaaga tctgaaatca tacgcatcat ccgattagtt
     7621 tcatcaagag aaacttttat gaaacttgga gcaatatctt ctttaagtgc accttcatca
     7681 agagcctcca agtaggattt aaccgaagtt aaaggggtcc ttaattcatg acttacatta
     7741 gagacaaaaa gacggcgttc acgttcttct ttttcttgtt ctgtggtgtc atggagcacc
     7801 acaaccaagc ccgaaataaa accactctct ctcctattca acgcaaagcg caagcgtaat
     7861 gagacaaact cacccatatc atttcggcta ttaacagtta ccactggtgt tttagatacc
     7921 aaatcacggt aggtatatga agtatcacct tctaacaaat ctgtaatgtt tttctttagt
     7981 gcctcttctt tacttaaatt taattgcttg cgagctgtct cgttaatcat gatgatttta
     8041 ccagaccggt ctgtagcaag tacaccatct gacatataag ccaaaatact tgccaagcga
     8101 tttttttctt gggcaagatt ttcatgcgtc aagcgaaaaa catctgatag gtcatttaac
     8161 tggtctgaaa gctccattaa ctcaatgtct gctttttcgt cgattatatc agtatagcga
     8221 ccattaatca agtctcggat tttatggctc atcatccgaa taatacgtgc atttcggtaa
     8281 tcacgcaccg caagatggat aaagtaaaaa gcaacaaaaa caagtaagat aaggatcgct
     8341 aattcaaatg tggataagtt tccaatgata tctctagtca taagatttca tgtagtaccc
     8401 aacaccacgt cttgttaaaa tatactcagg acgacttggt gtgtcttcaa ttttttcacg
     8461 gagacgacga acagtcacat caaccgtgcg cacatcgcca aaataatcat atccccaaac
     8521 aatttccaat aagtgttctc gtgtcatcac ctgacccata tggttagcta gatgatgcaa
     8581 tagttcaaat tcacgatggg tcaactctac ctcttgacca tgttttttag caacaaacgc
     8641 atctggtaaa atctgtaaat taccaatggt tagttcctgt gtacctgaag aagcattttc
     8701 ttctgcaaca gccgtttcaa tagtttcggt acgacgcaga tgagccttga cacgtgccag
     8761 caattcccga ttagaaaagg gcttggtcac gtaatcatca gccccaattt caagtccaat
     8821 aaccttgtca aactcactat ctttagccga caacataata atcgggacat gactggtttt
     8881 acgaatttcc ttggctactt caagaccgtc caactcaggg agcatcaaat caagaataat
     8941 taaatctggc ttttcttctt caaaaattgt taccgcttcg cgtccatcaa aagctgtaac
     9001 aatgtcataa ccttcttttg tcaaattaaa cttaataatg tcagaaatcg gtttttcatc
     9061 atccacaata agtatttttt tcatgtctat acctcagaaa gttcttgtaa ttgatattac
     9121 aatttgtgat ttttgtggtt aataaaaaat cacaaaacta tatttttcta aattatttct
     9181 acctgattat accaaaaatt cagcctaatt gacaatgacg actaccgtta caaatagagt
     9241 actttctaaa accaaccctt tataggatga atttgacgtt tgaattgctt agcagatttt
     9301 ttgactctgg caaaactact cttgttgtgg taagcaaaaa gtcctttggc attaaaataa
     9361 gagaacataa agtcatcttt ttgagctcta aaccactgac gaaatactct ttttggcgat
     9421 cgaaatcctt taagggtgtc ccttctaaac tgaggatcgt gacggctaat cggatcaaca
     9481 tctaaatccc aatgtctagg accatctgtg ccatagttaa aagatgcacc attgacaatt
     9541 cctttttcgg tcactacttc tgcatcaact tcattaagaa aaaagcctgt gctatctaga
     9601 ataaattcgg tatgaaacca aagaagtact tttatattat aggaaacttc ttgacttgga
     9661 aaaatgactt tattatcttc aaatcttagt ttattatgta acctggcaga atccatcaag
     9721 gtataatctg gtgcttgccg ccacaaacaa ggcccttttt tagacctcaa aaaaagggcc
     9781 agagcttggg cgtctgtcat ctcaatcatt ttataatggt ttctgataga ttgagcttgt
     9841 tgactagaga tgacataacg aaattgatgc aaacgctttt caagctcacc tgcttggctt
     9901 agtgttttgc caggaaaagc ttgatcaact aagctagcca actctttcca aaacatatga
     9961 tctggcaata gagatggatg gaatcgggtg agtagcgttt gagtttcatg caactgacca
    10021 cttagctcaa atggcatctc taccaaatca agaagaaacg ttagtaactg cttagctgat
    10081 tggttttctt tttcaatagg ccatattacc cagaaagttg gagaaccaag tcgattatca
    10141 atgataggct ctttagctat agcacgaaat gcttggtttg ataaacctgc gttttgatag
    10201 catttcaagg cctgatagcg atctaagata gcttgtttca tggccttctc ctcatctttt
    10261 ttgaccatat tataacacat ctaaagctga atcgtcactt gtatctcact ataagcaaaa
    10321 cgaaacctga agtggttaac taagccactg tttgggtatt ttatttaaaa gaacttctcg
    10381 attaatttta ccattatctt ttaaaggcaa acaatcaatc acaagatagt acttgggaag
    10441 ttgtccagag tttaaataaa gagctaaaaa gtctttaata ggtgctaggc aatccttctt
    10501 agtcaaaact aatactaata ttagggtttc gttttctcct tttcctatct ttaaagcgtg
    10561 cgcttctttg acgtttggcg cttggtgagc gagttcaact aggctaggca ggtggcattt
    10621 cactcctcgt tgattaaccc agtcatcttg tcgcccttct aaaattaaac ccgctgggct
    10681 catttttcct aagtctgaga cactgtatgg ttgtgacatt ccttctacac tataaggagt
    10741 ctctacaaaa atttccttat ctttgaaact gatagacaca tcaggaaagg gctgtcctac
    10801 caaaccatta attttgacag cagctctgcc attacaccac gttataaaag ataattcact
    10861 agccccgtag aaaatgacaa tttcaagctg aggaaatttt ttgtaataat gtcttagtaa
    10921 ttcttgtgat atcatttgcg aagaggtcaa taagtgagtc gcagtcatgt tgttcttagt
    10981 caaataaggt agcaagcgat ttaggtaggt cggtaaaagg taaaggtgac tcaccttttt
    11041 tgcttgccat aagcttaacc acgttttcaa agacagcttt tggcttaaaa ccagacatcc
    11101 cccggcccat agttgagcta atgctaagtt aagattgcca gtaaaactaa aactaccatg
    11161 taagaataga caactattac cagtcatacc aaacacctta ttttgataat caaaaagtct
    11221 cgtccaagtt gatagacaac gccaaaataa ttttgctttg ccagttgttc ccgaactcaa
    11281 aacagcaaaa tcagcttttt taagaagctc actatcgacg tgttttattt gctgctgaaa
    11341 tgtacctgag atattagggt gtaaaatgat aggacaactg ccttctttta atcctcgtaa
    11401 aaaagagagt aactgattaa gatagcgact atgactgatg atatatggta cactgtcttt
    11461 tattgtctga tcctttatta aaaccgcttg ccatagctct tgataagtca agcttatctg
    11521 atcggctacg atagcttttt tatttgggca ttgctttgcc caatattcta gctttgtcag
    11581 catgactaaa ctccttatga tattttagta aaacagcaaa cccttggcca ccagctgctg
    11641 ctatagcagc tattccatag cgtccatttt taatctctaa agccctcatt aagtgcaata
    11701 ttataatggc tgctgaggca ccatagggat gaccataagc taatgcacca ccaaatatat
    11761 tatagcggtc caataaatct ggataatggg tttcaaatag accatcaata acggcaaagg
    11821 cttcgttcca ttcaatcgct gtcatatctg ccatccctag accatgtttt tccaaaagga
    11881 cttgactagc cttaatcacc attaaagggc tacgctgtgg gtctcctgct acttctacca
    11941 catcaatcag tttaaaagct gaaggctgac tacttagctg taaaaaggca gcagcatcat
    12001 gggttaggca ggcattggct gcactaatca cgtgatcttc tcctaagata gggggtacct
    12061 ttgacaacac cttacttgac aagcgcggtc gaataccttg atcactggct cctggcaggt
    12121 ctagaataag atcagctaac agggcttgct cctggcaata actagccttt tgatgacttc
    12181 tcaatgtcca gtgattcaaa tactcctttg taaagccatg ctctcttgcc actcgttctg
    12241 ccccttcaat catcgcaaaa gggctgatac tatctggaga aaactgagct accttgtagg
    12301 ctccttggcg ccaatcagct gaagcatata ccgattcagg ttgtaaggag ctgctttcaa
    12361 tccctcccac taaaaggttg cttgccatac ctgccttgat tttagcataa cccacggaaa
    12421 gagctgcacc agctgatgca cactgcatat caaccgtcaa agcagagaca gattctccta
    12481 aatgagaata cagggtcatc aggcgcccaa tattaccacc cgttccgacg gcattgccac
    12541 aaatcacttg gtcaatggga actggatact tattttgtaa agcattgatg agctttgctc
    12601 caaggatttc tggttgttct ttagcaaatt gtttccctac taaaccgata ggggttctaa
    12661 ggcctgcagc aatataaaca tccgtcatta tattgacctc ctttattttc gatgtcctta
    12721 aatggttatt atataattat ttctgatggt tttctttttt gaactaataa ctgctaaaaa
    12781 tacacctaaa ttaatttaga gaatctcttt agtctcgcta gtgtgccatc aataaaatct
    12841 ataaaattct ctaacgtcat tgaaatgtca agtcccacaa ctattgtcgt agaagtcact
    12901 tactttgttg ctttaacatt caaactgtaa cctttgtttt tgatacaggg tgactttatt
    12961 atactggaaa accattccta agaaaagaaa atcttatata gaataaagaa ttagacacca
    13021 taaaaaagct aagctgtgac acttaacttt tttatggtat tgacaaacct tgtctttact
    13081 atttattgat agttaatgcc tctaactaaa ataaaagcca tgtctgtatc agcctgcaag
    13141 gcatctgcta agctggtatc gttactagat ttgacaggtc tcataaaggc aaaagatctc
    13201 aaagttccat aaacgttatc tagcaattgc atgcaaccac ttgaaatata tctgcttatg
    13261 ttattttacc gcccttaatt tagaccaatc tgctgatgat ggttccaaac aatgcctcta
    13321 ggaacctgca ctttcataag catctaggcc ccatttccaa agcttaagcg acaaggccaa
    13381 aaccagtaac gacaccacta ccaagcctcc aatattaaag agcaggtgct gacctgttaa
    13441 aaaataagaa gcagggtaat aagctgtaaa agcaaaggga atgacaaaac tgattaacca
    13501 ccgcaaaaag gaatggtaaa tggacatagg gtacttggaa aagtcattaa acatgtaaaa
    13561 aatataaata actgccccag actgcttggt ccaaaaagaa atgctggcgg tcgcaatttt
    13621 taaagaggtg taaatcaagg tcgcaaaagg aataaccaaa ataaacaaaa gcaccttagg
    13681 aagagtccat acgatactac cagccgtggt cactaataag ataaccccaa ccaataattc
    13741 acccagggca tccacttgaa atgtctcaac caaaacatga aacaaaggac tgattggtct
    13801 ggtgaggtac ttgtcaaatt ctcctttgcg gacaagccgt tgccctaaag cccaaagatt
    13861 gtcaaaaaag aggtgatcaa ttccctttgg aatcaaagaa aagccataaa taaaggcaat
    13921 ttgttcaaac gtccagcctt ctaaagaagg gatatgttgg aaaagtaccg ataaaaagag
    13981 cagattaagt ccctgagtga gaaaaacacc tagcactccc accacaaaat caaccttgta
    14041 ttccataatt tgtttgaggt attgtttgat aaaaatagcg tgcatacgtc tcaattttgc
    14101 catctcaccc tccttgaatc gttaaatggt actgaacctt tttccagatg acttgcgata
    14161 agactaccat caccagtaac caaaagattt gcaaacttag ggccaccatt atctgactaa
    14221 ggctgtattt cccaatgaca atcataactg gcgtgtaaac caaagaggaa aacggtagaa
    14281 aactaagcac tatataaacc actttaggaa aaaaagccaa tggaatcaaa ctgcctgaca
    14341 taaaggcaac caaggcattt ttcaataaat tagaccccca aaggttttta aagacaaatg
    14401 ctgaaaagcc aaaacaaatg ttgaaataaa aattgattaa aaaagctaat aaaaggctaa
    14461 ctaaatacag acaactgctg gctaggactt gcaaggtaga cagccccgcc atgactttaa
    14521 taccagataa gaccattaaa aaaggaaagc cgacactcat tagcacaatc cagcgaaaac
    14581 caatttccat aaagaggtaa gaggctgcaa aatgaactgg tcgaagcagg cgcatgatga
    14641 tagaaccatc tttcacttct tcgccaatca taaaggagct gtctgatttg gtcagtaaag
    14701 tggtcacaaa actcatgata atgtaaaagg tcatgtcaga cagagtaaaa ccattgatta
    14761 aggattgctt agacgaatca aaaacagcct tccagaggta ataagccaca aaagccccca
    14821 tgacatctcc aatacgatac aaaaagaaat taacgcgata ggttattaat tcctgaattc
    14881 ctgcactgag aaagggtcta taacgtttcc aaaatgacca catcttaaag ctcctttcgg
    14941 tagaaacgac gaacaatatc ctcaatatct acatcagtca tcttcaaatc cctgaccgca
    15001 aaatcagcca tggttttttg aataatgtcc gctgtttgat agcgcgaact gtcatattga
    15061 atgtctaaac taagctcatg ccgttccact gtgatgtcag gtaagcccat aaactgtgag
    15121 accacctgct cctgccctgg cttcaactca aaagacagac tcttcatttt tccaaagctt
    15181 tgctttaatt gggtcaccgt tccatcaaag atttcttgcc ctttatcaat catgataatc
    15241 cgatcacaga gctgttcaat atcactcaaa tcatgggtcg tcagtaaaat agttgtcttt
    15301 tcttcttgat taatttgagt aatggcacgc cgaatgttgt ccttcacaga aacatcaagt
    15361 ccaatcgttg gttcatctaa aaacaatact ttaggattat gcaacaagga agcagcaata
    15421 tcagctcgca tccgctgacc gagtgataag gtccggacag gatccttaat aaactcattc
    15481 aggtccaaaa cctcatttaa aaaatccatg cgcttgcgaa aggctttttc aggcacatcg
    15541 taaatttctt ttaaaacgac ataggtctct tgcaaggcca aatcccacca tagttgtgtt
    15601 cgttgaccaa aaacagctcc aatgtctctc acataatctt gacgattatc ttgtggaatc
    15661 tttccgttaa tgcgacagta acctgatgta ggctttaaaa tacctgttaa catcttaatc
    15721 gttgttgatt ttcctgcacc attggctcca ataaaaccta aaatttgccc tttgggtacc
    15781 tcaaaagata agtccttaac cgcctcaaag atttctcttt ggggatgaac aaaggacttc
    15841 aaggctccct ttaatcctgg ctctttaatg gttttggaaa aatttttttg aaggtgggac
    15901 acttctatca tcaccattta ccattcctcg tttctgttat cgtcttatca ccgttactaa
    15961 acaatttatt ataacaccat gaaaaagact gtgcaaccgt ttgcttaatt ttttaagaaa
    16021 gaaaaagaag cccataagga cctctttttg ccattgatta agcttgtgca tctggacatg
    16081 acttgcgagc aatgtctgcc aagatgtttt ccacaaattc ttccacagat tcagtgtgag
    16141 tcgccttact accatagcgg cgaacattga ctgatttgtc ttccatttct ttgtccccaa
    16201 caattaattg gtaaggaatt ttgctggttt gagacgcacg aatcttgtac tgcatttttt
    16261 cattgcggtc atcgacatct gcacgaacac cacggtcacg aagggttttt gctacttccc
    16321 aagcatagtc aatgtgggct tcatttgaaa ttggaatcac ggttacttgg tgaggtgcca
    16381 accaagttgg gaaagcaccc ttgtaagttt caataaggat agcagtgaaa cgttccatag
    16441 ttgagataac accacggtga atcatgactg ggcggtgttc ttcgccatct gcaccaatgt
    16501 atttaaggtc aaagcgttct ggcaacaaga agtccaactg aatggttgat agggtttctt
    16561 cgttaccaag agctgttttc acctgaatat caagcttagg cccataaaag gctgcttcac
    16621 cttctgcttc aaagtaatct acacccatct catcaagtgc agctttaagc atactttgag
    16681 cattttccca catctcatca ttgtcataat atttacgagt atcgttaggg tctcggtatg
    16741 acaaacgaaa acgataatca gtcaagttga agtcagcata aacatcaatg attaattgaa
    16801 gggcacgttg aaattcttcc tggatttgct ctggtgttac gaaaatgtgg ccatcattca
    16861 aggtcatttc acgtacccgt tgaagtcctg atagggcacc tgatttttcg taacggtgca
    16921 tcatgccaag ctcggcaata cgaataggca attcacgata agaacgcaca tgatttttat
    16981 acacttgaat gtggtgtggg cagttcattg gacgaagaac aaactcctca ccatctccca
    17041 tatccattac agggaacata tcttcttgat aatgatccca atgacctgat gtcttgtaca
    17101 attctacaga agcaagtggt ggtgtgtaaa cgtgttggta gcctgatgct aattctttat
    17161 ctgtgatgta gcgctcaagt gtacgacgaa tagtcgctcc atctggtaac caaaacggca
    17221 agccttgacc aacttcttgg ctaatcatga acaagtcaag ctctttacca agcttacggt
    17281 gatcacgttc tttggcttct tctagacgag tcaagtaagc tttgaggtct tttttatcaa
    17341 accaagctgt tccatagata cgttgcatca tgttattgtc gctgttacca cgccagtaag
    17401 cacccgccac atttagcaag tggaagactt ggatacggcc tgttgatggc acatgagggc
    17461 cacggcaaag atccacaaat tcaccttgac ggtaaaccgt caagccagca ccagcatgct
    17521 cattaatcaa ttctaccttg taaggatcat ctttgaacaa ttccaaagct tcttctttag
    17581 tcacttcttc acggatacat gggtaatttt ctgtcacgat tttttgcatt tcagcttcga
    17641 tacgtggcaa atcttcgttt gaaatttggc cttcagcatt atctgtatca tagtaaaagc
    17701 cttctgcaat ggcagggccc acacccaaat gaagatttgg gaacaagcgt tttgcagctt
    17761 gggcaaataa atgggctgca gagtggcgaa gcacctcata agcatctttg tggtcaggtg
    17821 tcacgatttc aatactgcca tcttcttcaa tggcacgagt ggtgtcaatg agttgatcat
    17881 tgaacttacc agctaaagct tttttagcca atgatttgct gatggactca gcaatgtcaa
    17941 acgttgttac accagattca aattcacgca cggcgccatc tggaaaagta atcttaatca
    18001 tttgctttct cctttaagtc agttaagatt tccactaaaa catggatagt aagacaaatt
    18061 agggacaaga ggttagtgaa tagctcaata ccaccacgta gaagaacaat accttattca
    18121 cgaatctacc ctccctagtc cttaaaaaca aggctaatcc cctccaaaac aaaaaaactg
    18181 accgcatccc aaaggacgca atcagcgtgg ttccacctta atttatgcag ggcaaaaaac
    18241 atgccttgca cctctagtgg cgataagggg gccacccttt tatgtttgca taaaaaccag
    18301 gaaggagtat cagattagct atccttgtgc tctttccacc aaccagcact cgcttaaaag
    18361 attctgtcca atctaacttg tcttcaagat aattatagca agttttcaaa aatttacaag
    18421 tcttaatcca gaaaatcttt gatagcatgg accagcttga taggagcctt gactactttt
    18481 actgaggtga tagctgtgac cttagcagca cgtttaggca agtgaatagc accttgcact
    18541 aattttagag aactactttt accagaatga ttaagataaa gactcagctt ttgagcttct
    18601 ttgctatttc tagcaattaa cgtatctaaa tagaacgtgt aaatagattt tccaaagtgc
    18661 tgtgctgaga tttcataacg tttttttgct aataaccgtt tatccataac tggtgttttt
    18721 agtatggcat caataatagc atcagttaaa tctgtttcag cgtaataaag agtgccaaac
    18781 attttatcag tcaccacatc atctaaataa ggattgccat gagcaataat aggagtgcca
    18841 ctagccaaac tttcaatata ggtcaagccc tgagtctcac tggtcgatgc tgagataaag
    18901 aaatcacaag ccttatagta cagagcaacc ttatcatgag gcaccatgcc tgtaaaggtc
    18961 acgtgtttgt caacctctaa ctgcatcgcc aagtgtttca aatcttgcaa ataggggcca
    19021 tctcctacaa taataagctt tatcttggca ttttcagcca aaatagctgg catctgattg
    19081 atgatagctt gaatattttt ttcataagaa atccgtgaca aactcaataa catggtttca
    19141 tcaccagcaa tgcccaattc tgcttttaag ttggttactt cttctgctgt gatgtcatca
    19201 cgaatatatt tttccaaagg aatgcctgtt gggataaccc gcttagggat agtaacttcg
    19261 taaccttcta gaagattgag gacaatccta cttgggcaga taaccccatc caaatccttc
    19321 aaatagcccc taagaagagg tttgaccata cttggtcgaa tgatttttcc gttggcaata
    19381 taactcacgt agtcctcata ttgggtatgg taagtatgga caacaggaat tcgcaaagct
    19441 ttgcctatca ttttccctaa caagcctaag ctaaactcag tttgcgtatg aataatatca
    19501 agattatagt gttttgcaat tttgtatgac gaaatgaggc cacgataaac cacacgtcta
    19561 tccgtaaatg acacaaaagg aacacttggc agtcgaataa tggtcgggtc ttcaaagcgt
    19621 ttgacatctc tatcagtagt ggtgaaaata taaacttcgt gaccttcttt ttctagctct
    19681 tcttttaacg tacgaatact agtagcgact cctgaaactt gtggaaaata ggtatctgtg
    19741 aatagaccta cacgcatctt ataactccat tactttttta tagacatcta ctaaggcatg
    19801 gccaaccgtt tctaggcgac gactctgggc aaccttgtaa ccagcttcaa ctttgttgct
    19861 ggcaccagaa aagacttttt tcagagcttc tataaaacct ggtatatcgg ttgctaattc
    19921 cgcactactt tgatcaaccc atccgtagta aactggtata tcacgtaaaa caaggtgctg
    19981 acgactggcc aaggcttcta agacaacaat gccttctgtt tcttcacgac ttggaaagaa
    20041 aaaggcatct gcaccagtca tggcaccttc ataaacatcc cctttaatgt atcctgggaa
    20101 aataagattt ttcgggtggt taccattgac catttggcga acttgagcag gaatgaccca
    20161 tttgttggtc tcgccaaacc agataaaacg aacatctggc atagcttggg caactttgac
    20221 aaagtcatca attcctttcc tcagaaaaaa taatcctgct cccataacca ctttttcacc
    20281 ctctttaatg tcaaagtagc gacgaaaagc tgcttccttt ttagaatctg ctccgtactg
    20341 ctccaaatca atcccatttg acactgcaaa aataggtgac ttcactccat aactctcaat
    20401 caaagactta gaatataggg taggggtaat gatagcatct gccttattgt aaaagtgaca
    20461 aaggtatttt ttaaaccaag gagataatag atttgaaaaa ataaaagaat ttctaaaatc
    20521 ttcttctgta gaatgcccat gcatgataac cttcttacca gctttttgtg cttttatcat
    20581 cagcagccaa ctttttaaac cataggtatt gagatgaacc aaatcataag tttctcttgg
    20641 attagtcgta aaatgttgac caacaagtga caaggcttta gcctgatgct taatcgctcg
    20701 accaattcct gattttctta gataattttc tgcttctaaa tacaataaga ctttcataag
    20761 ttctattata gctcatttta tagtattttt cactaagaca tgcaaaaatc agccctaagg
    20821 ctgattttag tattgaagaa acagtctatt gtgatacttt ttgttagatg gtgctcataa
    20881 gtcacagtta cttagttgtc ccacgttttt taataccatg attcaaaaga atttcttttt
    20941 cttccaactc ttctttgttc atgattttag tcaacatccg catgctaaca gcacctaagt
    21001 cataaacagg ttgactgata gaactcaaat tgggacgagt gtattgaacc actggtgaat
    21061 cgttgctggt gatgatttca aagtcctctg gtacgcgttt acctgcttca aacaagccgt
    21121 ttaaaaggcc tgctgccaat tcatcttcag ccacataagc cgctgttgct cctgagttaa
    21181 tgacgcgctg cgccaattca aatccttctt tataagaata gttcgcttca aaaacaagac
    21241 cttctttgaa gtcaagctta ttgtgcttca acccttcttt gtaacctgct aagcgcactt
    21301 taccattgat atcatcaatg agtggtcctg acacaaaagc gatacactta tgattttcag
    21361 ctaaaatatc aacaacgttt gacaccgcag ctctatagtc aatgttgacg cttggtaatt
    21421 gatgatcaag atctacagtt cctgccaaaa caactggagt acgagagcgt gaaaactcgg
    21481 cccggatttt ttctgtcaag tgatgcccca taaaaataat accatccact tgcttggcaa
    21541 aaagggtatt gacaacatta acctccttat catcatcttc atcactggag gcaagcacaa
    21601 tattatattt gtacatagcg gcgatatcgt caataccctt agctaagata gaaaaataac
    21661 tatttgcaat atttggaatc acaacgccaa cggttgttgt ctttttgctg gcgagaccac
    21721 gcgcgacagc attgggacga tagtcaaggc gatcaataac ttctaaaact ttcttacgtg
    21781 tattttcctt aacattttta ttgccattaa caacacgact aacggttgcc attgaaacac
    21841 cagcttcacg ggcaacatca taaattgtaa tggtatcatc tgtattcatt ttttatcttc
    21901 ctttctattt gaaaatgacg ctttcaaaaa gtattttagc atgatttgta accactttca
    21961 agtgttatag gttaattttt gaaaaagttt tcaaaaatta actcgaagct tgatttttta
    22021 agcttttttt gaaaaaatag taagtagaaa gaaggttagc ctatgacaaa attagaccaa
    22081 atacgtttgt atcttgacca aaagggagct gaattggcga ttttctcaga tcctgttacg
    22141 attaactatt taactggatt cttctgtgac ccacatgaaa gacaactgtt cttgtttgtc
    22201 taccatgatt tagctcctgt gctttttgta cctgcccttg aggtggccag agctagccag
    22261 gccatatcat ttcctgtgtt tggttatgtt gattctgaaa atccttggga aaagatcaag
    22321 gccgttttac caaatacagc agccaaaacc atttatgttg aatttgacca ccttaacgtc
    22381 aataagttcc atggcttgca gactattttt tcaggacaat ttaacaatct aaccccttat
    22441 gtccaaggca tgcgcctcgt caaatcagct gatgaaatca ataaaatgat gattgccggg
    22501 cagttcgctg ataaggctgt tcaagttggt tttgacaata tttccttaga tgctaccgaa
    22561 acagacgtca tcgctcaaat tgagtttgaa atgaaaaaac aaggcattca taaaatgagt
    22621 tttgacacta tggtcttaac tggaaataat gcagccaatc cccatggcat tcctggaaca
    22681 aataacattg aaaacaatgc ccttcttctt tttgacttag gtgtcgagac cttaggctac
    22741 accagtgata tgaccagaac tgtggctgtt ggtcagccag accaatttaa aatcgatatc
    22801 tacaatctct gcctagaggc acaactagcg gctattgact ttatcaaacc aggtgtaaca
    22861 gctgctcaag tagatgctgc tgctcgtcaa gtgattgaaa aggctggata tggtgagtac
    22921 ttcaaccacc gcttgggaca tggtattggc atggatgtcc acgaatttcc ctccatcatg
    22981 gctggcaatg acttggtcct tgaagaaggc atgtgcttct ctgttgaacc tggtatttac
    23041 attccaggaa aggtcggtgt gcgcatcgaa gactgtggcc atgtcactaa aaatggcttt
    23101 gaagtcttta cccatactcc aaaagagttg ctttattttg aaggctaagc ccctatcatc
    23161 tggttaaaca aaccctcgcg aaaggaaggt attcgtatgg atcaaaccat tcatcaccaa
    23221 atacagcaag cactacactt tagaacagcc gttcgtgttt ataaggaaga aaagatttct
    23281 gatgaggatt tagcccttat ccttgatgct gcttggttaa gtccttcttc tgttggctta
    23341 gaaggctggc gctttgtcgt tttagacaac aagcctatta aagaagaaat caagcccttt
    23401 gcctgggggg cccagtatca actggagaca gctagtcact ttattctttt aatagccgaa
    23461 aaacatgcaa gatacgatag ccctgctatc aaaaatagcc ttttacggcg tggtatcaaa
    23521 gaaggtgatg gtctcaacag ccgcctaaaa ctctatgaat ctttccaaaa agaggacatg
    23581 gatatggcag ataatcctcg ggcactcttt gattggacag ctaaacaaac ctatatcgct
    23641 cttggtaata tgatgatgac agctgctctt ttgggcattg atacttgccc tattgaaggc
    23701 tttcattatg ataaggtcaa tcatatccta gctaagcata atgtgattga tttagaaaaa
    23761 gaaggcattg ctagcatgtt atccctaggc tatcgcctgc gagatcccaa acatgctcaa
    23821 gttcgtaagc ctaaagaaga agtgatttca gtcgttaaat aaggagatta aaatgaaagc
    23881 attacatacc tgtatccgcg tcaaagacct tgaccagtcg gttgcttttt acacaagcgc
    23941 cttccctttt aaggaaaact atcgtaaaga ttttccagat agtcaattta ctcttgttta
    24001 tctggcttta gaaggagaaa gttatgaatt agaattaacc tacaattatg gtcatggcga
    24061 ctacgactta ggaaatggct atggtcatat tgcccttggc tctgaacatt ttgaagcaga
    24121 ccataaaaaa catcgacaag caggttttcc agttaccgat atcaaagaac tggctgacaa
    24181 atctgcccgc tattatttca ttcaggatcc agatggctac aaaattgaag tcattgattt
    24241 aaacaactaa tactattaac aacagaagct ttaaagcttc tgttgtttta ttttttaacc
    24301 tgacgattgg gacaatctca ttattaacag agttttgaaa tatctcagct tttgtgttac
    24361 aattgcccta aaattccatt tgaaagaaaa gtctatgaca ctactatcta tcattgtccc
    24421 ctgctttaat gaagaagcaa acattctccc ttattttgaa gaaatgcatc aactagaaac
    24481 gtccatgacc aaccaacttg cttttgaata catttttatt gatgatggtt ctaaggataa
    24541 caccttgggt attttgcgtg agctagctgc tcgctttcca aatgtgcatt atctgtcttt
    24601 ttcacgccat tttggcaagg aagctggact cttagctgga ctaaaagaag ccaaaggcaa
    24661 ttacattact gtgatggatg tggatctgca agatccaccc gaacttttgc cagttatgta
    24721 cgctaagcta aaagagggtt atgacatcgt tggcaccagg cgccaaaata gacaaggaga
    24781 accactaatt cgttcaatgt gttcgaatct attttatgga ctgatcaaac acttatcaga
    24841 tactgaaatg gtcaatggag ttcgggatta tcggttaatg accagacaag tcgttgatag
    24901 cattcttgag ttgggagagg ttaatcgttt ttcaaaaggg atcttttcgt gggttggtta
    24961 tcgtatcacc tatcttagtt ttgaaaatca aaaacgcaaa tatggaaaaa gtcgttggca
    25021 tttttgggag ttgctccgat attctttaga tggctttatc aacttttcag aaatgccgtt
    25081 aaccattgct acctggacag ggactttcag ctttttgatt tctattttcg ccatcttatt
    25141 tatcattatc agaaagatac tctttggtga tcctgtctct ggttgggcca gcactgtctc
    25201 tattatttta ttcatgggag gcattcagct cttttgcatg ggtattattg gaaaatatat
    25261 ttcaaaaata ttccttgaaa ctaaaaaaag gcctctctat attatcaaag aaaaacatta
    25321 aattaaaaca tttttctcat caatcgtttc ctactccttc tgtgcgcgaa gctttctttt
    25381 taagcccgtt ataccaaatg ataatgacct ttccaaaata gtatcacttt ccttaacact
    25441 ttaagtagaa aaggaactat taggttgagc ctttttgcaa atcctagcga ctaatgttat
    25501 aatcgtcata ctattgaaaa aggagttctt tatggagtgg attaaattaa tcggtattgt
    25561 gattatcgta ttagggttta ttttaaaatt tgatgctatc gctaccgtag ttgttgcagg
    25621 acttgttacc gcgctggttt caggaatttc gtttattgat tttttagata ttttaggaaa
    25681 agaatttacc aatcaacgtt tgctaaccat tttcttcatc actttaccgc ttatcggctt
    25741 gtcagaaact tatgggctga aacaccgagc tactcagttg attcaacgtg ttcaagccct
    25801 taccgtcggc cgtttattga ctctctacct tattattcga gaattagcag gtctcttttc
    25861 gattcgacta gggggacatc cacagttcgt tcgccccttg attcaaccta tgggagaagc
    25921 tgctgctaaa gccaacattg gagaagagtt gaccgatgca gaaaaagatg acatcaaagc
    25981 tatggcagct gccaatgaaa actttggcaa tttctttgcc caaaatacct ttgttggcgc
    26041 aggaggtgtc ctacttatcg ctggaacttt agaacagctt ggctatgatg gtaaccaagc
    26101 taaaattgca ttttcttcta ttttaattgc tattatctct attattatag ttgctattta
    26161 caattacctc tttgagaaaa aaatggaacg tcaacatcag aaaggagata actaatggct
    26221 aacattgcaa accttgtttt agaaacgata tatatcctta tcggcttgca actgtttcac
    26281 acagcctact gcacctttaa agataaaacc aaccctgtct attttgggac agctctgttc
    26341 tggggattgc tgggtgttac cttcgttggc ggtgcctttt tgcctaataa agttatcggt
    26401 tttatcgtga ttgtcctagc tcttttaacc ttgtttaagc aagttcgtat tggaacatta
    26461 ccagccttta atgaacaaaa agctgaagaa agtgctcacc gcattggtaa ctggattttc
    26521 ttaccagtta tgttaatggc tatgatttct ctacttcttg ccttgatcct tcctgatttc
    26581 agtaaaagtg ccattgggat tgctggtatc ttagccacta ttgctatttt aataatcact
    26641 aagcaaaaac catctgctct tttagctgaa aataatcgga tgaaccaaca agtgtccaca
    26701 agcggtattt tgccacagct cttaggagct ttaggagcta tttttgcagc tgctggtgtt
    26761 ggtgatgtga ttgcttctct cattcgggag attgtacctg ctgatagccg cttctttggt
    26821 gttctcgctt atgtgcttgg catggttatt tttactatga ttatgggaaa cgcttttgct
    26881 gcctttaccg ttattacaac cggtatcggt gttccttttg tttttgcttt aggagctgac
    26941 cctattattg ccggtgcttt agctatgact gctggttttt gtggtacctt attaacacca
    27001 atggcagcaa actttaatgc cttgcctgtt gctttgatgg agatcaaaga tcgaaatgca
    27061 gttatcaaaa agcaagctcc tatcgccctt gttttaatta ttagtcacat tgccttaatg
    27121 tatttacttg cttattatta acttttttgc taagttagta gcgtcagtta ttcattgaaa
    27181 ggacattatt atgaaaattc ttgtaacagg ctttgatccc tttggcggcg aagctattaa
    27241 tcctgccctt gaagctatca agaaattgcc agcaaccatt catggagcag aaatcaaatg
    27301 tattgaagtt ccaacggttt ttcaaaaatc tgccgatgtg ctccagcagc atatcgaaag
    27361 ctttcaacct gatgcagtcc tttgtattgg gcaagctggt ggccggactg gactaacgcc
    27421 agaacgcgtt gccattaatc aagacgatgc tcgcattcct gataacgaag ggaatcagcc
    27481 tattgataca cctattcgtg cagatggtaa agcagcttat ttttcaacct tgccaatcaa
    27541 agcgatggtt gctgccattc atcaggctgg gcttcctgct tctgtttcta atacagctgg
    27601 tacctttgtt tgcaatcatt tgatgtatca agccctttac ttagtggata aatattgtcc
    27661 aaatgccaaa gctgggttta tgcatattcc ctttatgatg gaacaggttg ttgataaacc
    27721 taatacagct gccatgaacc tcgatgatat tacaagagga attgaggctg ctatttttgc
    27781 cattgtcgat ttcaaagatc gttccgattt aaaacgtgta ggaggcgcta ctcactgacc
    27841 gtgacgctac taaacctatt ttaaaaaaac agagatatga actaactctg ttttttttgt
    27901 gctaaaaatg aaagacctag ggaaactttt catcggtctt tctcaattgt catcttaatc
    27961 taatactact tctaacatca gcgggtatag tttgccagta attaagaaac gttgttgatc
    28021 taaatgagca atcccattca aaacattaag gtcagggtaa tgggacttat caagatttaa
    28081 ggcttttaac aaaggactaa tatcataggt ggctaccacc tttccagaat caggttggag
    28141 tttgacaata gtattggttt gccaaatatt ggcatagaga taaccatcta catactctaa
    28201 ttcgttaagc attgagatgg ggacactttc tatagcaact agtacggtat ccaataaagc
    28261 aaaatctttg gggtctcgct tttgcaaaaa agcatttcca ctagtcatcc aaagacactg
    28321 gttttcctta tcataggcta atccccagcc atctccttca aatggatagg cccctaaaca
    28381 attgcaggta gccttatcaa acttgtaggc tacaccctct ttataggtta gtaaccaaaa
    28441 ataatcctca acaactgtta gcccttctgc aaaaactgta tctggaaaag ctattttttc
    28501 tgaaaagatc tcttgagtaa ggtcatacac ccctactttt gagaaaccat aacgaccggc
    28561 actaagtaat atatgattgt tgttgagttg ttctaatccc tgcgtgtata agttgctatc
    28621 ataagaataa gttcgtaaca aacgaacttg tcctttagtt atcataatac tcattcacct
    28681 taccttgcat tgtagtgttt catttgtttt ttaatatctc tttcctgatc acggcgttta
    28741 atggtttcgc gtttgtcata ctcgtgtttc cctttagcta gaccaatcag aactttagca
    28801 aagccatcct tgaggtaaac tttgagagga accaaagtca taccagatcc tttaagttca
    28861 tttgctagat gcgtaatctc acgttttttg agcaacagtt tgcgggtccg ttcaggatca
    28921 gcgttccaaa tattaccttg ttcaaaaggt gcaatatgca cgttgaccaa ccacgcttcc
    28981 ccattcttaa tttgggcaaa gccatctttc agttgaatac gagctgcacg aacactttta
    29041 atctcagttc ccgttaagac aatccctgct tcaacggttt caacaatgtg ataatcatgt
    29101 ctagcctttt tattttgcgc cagtatatga ccttcacctt ttgccatagt taactccttt
    29161 tacgactctt cttttttgct tgttctttgt aaaatggttt tttagaccct tttttagttt
    29221 tacccttggt ttttgccttg gctacttctt taggttcttt tttctttgtc cctttagatg
    29281 attttgagga tttacggcga tctcgtcgac tagctttatc cgacatcttg attttttcaa
    29341 ccacatcaaa gtcgctaggt aaatactcaa agtcaatgtc accagtttcc ttgtcagcct
    29401 taaccaattt cacacgaata ggttgaccaa ctttaaagac tttacctgat ttttcacctt
    29461 gaaggcttag cgttctttca ttaaagtgat agtattccgg taagctagtg atatgaacca
    29521 aaccttcaat cgtatttggc aattctacaa aaaaaccaaa tttaacgaca ctggccacga
    29581 taccgtcaaa ttcttcaccc acatactctg ccatatactc agcttttttc atggcttcaa
    29641 ccacgcgttc agcatcaata gcacgacgct ctaactgtga agaagatgtt gctaattctg
    29701 gaatgatctg agtaaaatgg tcgcgctttt cttgactagg ttgactgtac tcacgaacca
    29761 tgcggtgaac caacaagtca gggtaacgac gaatcggact ggtaaagtga gtgtaatatt
    29821 ctgcggccaa accgtaatgc ccatgattat gttcagaata tcttgcctgt tgcatagagc
    29881 gtaagagcat catgttaagc acttctgctc ctggttgacc ttcgactttt gccataaagg
    29941 cttgcaaggc ttcctgagaa atcttgttgg ctgttccttg aatgtgaata ccaaaggtgc
    30001 tagcgtaatc aataaattgt tgaagttttt cggcctttgg ttcttcgtga atacggtaga
    30061 taaacggtaa cttagctttt gcaaaatgtt ctgccacaca ctcattggct gctagcataa
    30121 aggactcaat catccgctct gcaattcccc tttgacgaag caccacatca accggcattc
    30181 ctttgtcatt aacaataact ttagcttctt gcgtatcaaa attcaaggcg cctcgttttg
    30241 accgcatagc ttccaaaatc ctatgcaaag ccaccatgag ggtcacatca tcagcaatgc
    30301 tagcgaattc ttggagcgct tcttcatctc ctgcaatcat gtcattgacc gtactatacg
    30361 tcattcggta agttgtctta atcactgatt gacagatttg ataattgacc acatgccctt
    30421 gagaattaat ttccatcaag gctgactggg tcaaacgatc aacgttaggg ttcaaagagc
    30481 agatgccatt tgacaaacgc tctggtaaca tcggaaccac acgatcggtg acatagacag
    30541 aagtgccacg ggcgatagct tccttatcaa gggcagatcc ttctgtcaca taatatgaga
    30601 catccgcaat atgtacccca agttcatagt taccgttatc caatagctta atatggatag
    30661 catcatctaa gtctttggcg tccgcaccat caatagtaat ggtggtttct tgacgcaaat
    30721 ccacacggcc tattaaatct ttagcagttg gtgcttctga aatagcattg gcctcagcta
    30781 aaacttctgc tggaaattct gacacgatat ccatcgattc aaggacttct aggacatcaa
    30841 ttccaacgtc tccttgatgg cctacgatat cacgcacact ggctacaaaa taatcgtgcc
    30901 cgcgtgtcgg gtatttatca atatcaacct tgatgatttc agtgccttta agcacaacag
    30961 gttctttttt gatatagatt ttttgttgaa tcttttggtt tttggacctg atataaccag
    31021 catattttgg tttgtcatca tctaaaataa aggttccaac agctgttttt aaagaacggt
    31081 caacaatagc aacgacctta gcttcagccg ctgtgccttt gagacggtct gctggctttt
    31141 taaccactac ttcgacagta tcaccatcaa tagcataccc aacatcatta cgaccgataa
    31201 acatgtcatc ttcattctca tccacatgta agaaaccaaa gcctgcttta ttggcacgaa
    31261 aaacaccctg aacagtaggt tcttttttct tttcacgctc ttttctaaga gccagactgc
    31321 catcatctga aaaccgtaac aggctctgac tttccatttt ggaaatggtt ttaataaggc
    31381 tgggaaaatg cttagctcca gccatctcca aggccgcagc caagtcgttc acattggact
    31441 tgccatgctc cttgaggtaa gtcataattc tttctttcat catacctaat ttctatttct
    31501 gttttgtttg ttggaggata tcaatccgtt tcgctgataa aaaaatgagc tagactaact
    31561 ctgtcaagct cactccttat ttacttgata aaatggcaag cacaagtgca atcgctagcc
    31621 aaaaaaatac tagaactgct gtgaatcgtt gcatgaatgc ttcaaagcca cgagcttttg
    31681 tacgttcaaa caaggcttct gaaccgctgc tatcaaaaac attgctactt gggttttttt
    31741 gaggttgcat aaaaatagca atcacaagca ataccgacag tactagcaat atcgtaagta
    31801 gtaagttgta catgttattt cctccactat tgtcatgacc attctaacac aattcttatc
    31861 aagtttcaac atgcagggtc acttttctct ccttggggca gtatttggga acttttattt
    31921 tttccggatg actgctttta tttttactgg ttagataatt gttactgcca cactcactac
    31981 attctaaatt aatttttact ctcacacaat atccttaact ttaatatatt ttcgaaatat
    32041 aatcaaactc catattaaat taacaaacac aatcaaacta gtcacataaa aaacagaacg
    32101 gtagcctaac actacagcca catttgatcc gataaaaggg ccaatgactt gaccaaggtt
    32161 actaaacatt tgattatagg caaatactct agaaatacct tcttttggtg ttaacttagt
    32221 tagtaaagag ttaatacttg gcatcaaagc gcccacacca aacccataag caaagcgtag
    32281 tactcctaat tgaaaactgg tctgcgctaa ggcactgcta aaatacatga taaagctata
    32341 acacaaagcg gctaacaata accgatgatt gccaaaacga tctcctaatt ttcctaagta
    32401 agaactgcta aataagctag aaaaccccat ggccgaaact accaggcctg aagtaaacat
    32461 taagttgtga gtttgaccaa gatgacgaat atacaatgat aaaatggggg ccactgattg
    32521 agctgaaatt tgaataatca tactagtcac aaacaaacca agcataatct ggggactttt
    32581 tacctgtttt aaaatgactt ttgtaggtat catctcaaag cgcctaatcg gcttaaactc
    32641 ttctttaaca taaacagctg tcattaaaga acataaaaat aatatcacac caactaataa
    32701 gaaaacttgt cgaattccta atagctctgc caaaatcccc cctagtaaag gaccaattaa
    32761 agcgcctgct gtcactcctg ttgctaatgt gcctaaagca taacctgact cctcttttgg
    32821 ggcttggctg gcaatcaagg cagtggcatt tggcacatag cccgcaaaga cacctgttaa
    32881 taatctcaaa atgagtaacc aaaacacatt aggaataata gctaaaccac ccatggtaaa
    32941 ggtcatgaca aaacttgctc gcagcatcat aggttttcgg ccataacgat cagccaactt
    33001 cccccaaaca ggagcaaata aagctgaagc aagtgccgtc acagcaaccg ccagaccagc
    33061 atagtattct actaattctt tcggagtacc taaattttcc acatacagag ccataaaagg
    33121 cataacaagt gaaaagcttg ccccagtaaa gaagttacca agccaagcca cttttagatt
    33181 ttgccgccag ttcactgtcg ttaccgcttt atcactaata gatcatcatc ttctttccat
    33241 cgggcctttg attattataa cacatttctg ccaaaaacag tgtcccataa tagtgctaag
    33301 tctcatctga tagccttcat cgtttacgta agctacccag taaacctctg accagttctc
    33361 gcccaattgt tctaaccgtc gtactaataa acgcatctgt tgctttttcg acgactgttt
    33421 ttcgtggacg cccaacagaa cggcgactag cttttttggt agctgcttgc gccttgatgg
    33481 cttctttagc ttctttttcg cgttttgctg tcgctatcgc ttcttgggcc agtcggttgt
    33541 cttctaaaac cttagcagct aatttttcat aagcagattc acggtcaatg gactgactat
    33601 atttactggc aaaaggtgaa gactgcacaa gctgctgact ttctatctct gacaaaacag
    33661 caaagctact cttaggcggc atgatatagg cacgttcaac gatggatggt tgtcccttat
    33721 cattcaaaac agaaatcaag gcctcaccga cttctagttc tgtaatcacc cttgccacat
    33781 ctaagtcagg attttgtcgg aaagtatccg cagcgacacg aaccgccttt tgttctttcg
    33841 gtgtataagc gcgcaaggca tgctgaatac gatttccaag ctgagccaaa accgtttctg
    33901 gcaaatcaag cgggttttga gtcacaaaga aaatcccaac tccctttgaa cgaataagtc
    33961 gcacaatctg ttcaactttt tccaaaaaga ccttaggagc gtccttgaac aataggtgag
    34021 cttcatcaaa aaagaaaacc atcttaggtt tgtccaaatc cccaacttct ggcaataatt
    34081 cgtacaactc agacaagagc caaagtaaga aggttgtgta aagggtagga gattgaaaaa
    34141 gcttagtcgc tgacaaaatg ttaatggctc cataacccga agcaacatct aattgcatca
    34201 aatcagccac atctaaagca ggctctccaa aaaattggtg ggccccttct tgttctaatg
    34261 tcaagagact tctttggata gtcccgatag attgcttggc gatattaccg taatggctgg
    34321 agtagtctga ggcatggtca ccaacttctt ttaagatagc ctgcaagtct ttcaaatcaa
    34381 tcaaaagcca acctttctcg tcggcgattt taaagacgat gtttaagaca cctgtctggg
    34441 tatcattaag attcaataaa cgcgacaaca tcatcggtcc catttcagaa attgttgtcc
    34501 gtaagggttg accgttttga ccaaaaacat cccacattct tacaggaaag gcctgaggct
    34561 ggtaatcact taccccgatt gtggctaaac gcgcagccaa tttatcagtc acctctcctg
    34621 ctttagtaag attagacagg tctcctttga tatctgccaa aaagactggc acaccagcta
    34681 aacttaattg ctctgctagc acttttaagg tcacagtttt acctgttcca gtcgctccag
    34741 caatcaaacc gtgacgattt agcatcccta attgtaaggc tatcggttga ctgccttttg
    34801 caattgtcat tgtagtcata ggcttcctct tttttgatga tcatacttgt cgatatgtgt
    34861 ttacccataa gttaaagtgt ttagaagggt ctcactctta atactattat aacatataac
    34921 ccttgatgcg ctaatttaaa agggaccagc tagttttaga cagaaatagc ttgattttga
    34981 cagctatgat acgaatctct cagcttagct acctcggatt ggctaatgac aacaacgcag
    35041 attgtacttg ctttattaag gctgcaatat ccccactatt atcaatcact agactggcat
    35101 agggcttttt ttcctctatt ggtaactgac tggctattcg ctgccttgct tttcctttgt
    35161 ctaaacgatt tctagccatt aagcgctgca attgtgtctg agcatctaca taaaccagcc
    35221 aaatcgcatc aaaccagtct tggtagccca attccattaa aatgggaata tccatgaaaa
    35281 aaatggcttg gctctgtgct aagtggtcac gcttagccgc caattcttcc ttaatgattt
    35341 gattttgaat ggctgaggat gttgccatat tatctgggtt tgaaaaaagc atttctgaca
    35401 gctttgtgcg atctaactca ccatctgctt ttaaaatctg attcccaaaa gcttctctaa
    35461 gagcctcgta aagacgaccg cctttttctt gcaagtcatg gaccacttga tccgcatcaa
    35521 tcacctgata accagctttt ctaatgacct taaccacagt cgattttcct gatgcaatgc
    35581 ctcctgtgat gccaataatc atggtctttt tttctggcat tttggacaaa tgtgcgtccc
    35641 ccttcctcca acttttaatt tgacaatagc ctgtccacaa cgaggacacg gtttcccagt
    35701 ttgaccataa acctgcaaat agtcctgcat ggtgccatca gctcccaaag cattacggta
    35761 agtacggacg gtcgaaccgc ccttttcaat tcctaaagct aggattcgta tggtttcatc
    35821 atgcagccgt tttatctccg ccttattcaa cctagaagac gcagttcctg gatgaacctt
    35881 agcagcccaa agtacctcgt ccacataaat attccctaaa ccagcaacca aggtctggtc
    35941 taacagatgt ggttttatgg gtttttggga ggatagcaga gcagcctcaa aggtttttaa
    36001 cttaaaggtc tctttctttg gttcagggcc tagttttcgt ttggcaaaaa acgctgataa
    36061 ttgagatttt gctatcaaat caaaggttcc aaatttacgc acatcttggt aaaccaaggt
    36121 cgaaccattt ttcaattcaa aaaagacatg aaagtgtttg ttatcaggga cctcatctgg
    36181 aaaaagcaaa tatttgcctt ccatccgcaa atgtgatacc aacactaatt gccccaaatc
    36241 aattaataaa tattttcccc gacggccaac tgactgaatg atttgaccag gtagggtcag
    36301 ggcaaacgtc tctaagtcgg ttttaaccat ctttggcact ttaagcgtaa cagccacaat
    36361 ttcttggcca agcactaaag tctcaagccc tcgtcggacc gtttcaactt ctggtaattc
    36421 tggcataatc cgttatttaa aggacagcta gaccctttgc tcctacaaag aataaactca
    36481 gtataaaaaa gtcactcaat agactcaggt ctaggctatt gactgcgttt caaaaaacac
    36541 agctgtcctt ctcctttctt atttcttatt ttacgaacac atctgataga aagcaactca
    36601 taaatctgcc tcagaccagt cctcatcccc cttacctccc agcactattt ggcggtaatg
    36661 ttccttataa ctataataca atgagtcctc tccaagatac ttaaaaatct gcaaggcctg
    36721 ccgcatgtcc tcttctccag acatttcttc ctgctttaat ttataatacc catgcacata
    36781 taagaaaaca gtcttttcat aaaaattgag ctcgtctcgc agcaaaagat caattttgtt
    36841 aatcaaatag cgactatgtt caaagcaaga atggtcaata ctgataatga gacaattaat
    36901 ggataactga gtcactaaca ttttattggt tttattttgt tccgaataag caaaagatgc
    36961 taccatttcc ttagtcaata aaaatagggt attgtaattc atgaagcgcg agcaattccc
    37021 cagaagaatg atttcataat atccccactg ttccacttta aataaataat ctgtgaggcg
    37081 agtcaattct tcttgactag gtgcaattga ggagtcaata gaaaaaagaa tagctttaat
    37141 catcgttcgt tcataatctt tatgggcata atccttcaac agtttggtca atttaaccac
    37201 gtttttctca gcataacatt ttctcgcctg acttaagagc gtgaaaaaat gcgtatgcgt
    37261 cttggaatga gccgaaacaa attcgtcaat cgtaatattc agtttatcca aaagattaag
    37321 caagcgactg caggtgattt ctgattcccc tcgttcaaat cttgaaattt gtgacttgga
    37381 caggtattca tctgctaaaa aagaaatgct aacctgctta cccttacgta atcgccttaa
    37441 ggtttttccg agttcttttt ccatttttcc cactttcaca acaaaaaatt aaaatctgct
    37501 aaatccatta tataatacaa gtacaaaata gaaaatcaga aaggagacag tcatgaaaaa
    37561 agttaataaa gctttgcttt ttacattgat catggatatc ctgattatcg ttggtggata
    37621 acctttcgct taaaaacaat ccacttttgg gaaaccctta tatttagttt gtaacaggaa
    37681 aactaataaa tattaaaaag agtgttagcg acctagcggc agctttactc ttaagtgcgt
    37741 ttgctgccat tgacagcaag gtcaaagcta atgaaacagc aggagcatac cgttatgatg
    37801 tgtctgaaca aaacacttac tatcaaacta tcagctccat taaccagcaa cgacctggtg
    37861 ccactctcga cgaatgaggt gattattatg gaacccttac ttcatttact tcccaaaatc
    37921 gtaccagtac ttatacactt ggtagacaaa gccaacgtat catggttaac agtgatatta
    37981 cagttaccta tactcttaaa gacaatttgg tagcccttca taaggaatat aaaacctttg
    38041 tcaaaaaaat attacagata aaccgatcac cagtgactac gacaaggcta aggttattta
    38101 taaccattta ctcaacgaat acacttacgc cacaaaataa cttagcacca atcacaaaac
    38161 cgtaagcagc atcaacaatc atactcctaa agctctttat cgtggcaagt gtggtgtttg
    38221 tcaagcttat gccgtcatgt ttaaagatat ggcagaagct gcaggcttat cagcttggta
    38281 tgtgataaaa aaggattgaa tgagcaccat gcttgaaaca tcgttaccat tcatggtgtt
    38341 aattcctacg ttgatgctac ctggaatgat tcagcataca ccacaaggta tttccttgct
    38401 ggaaaagacg tgatgaatac tgagtaccgt ttagatagcc agtacaacca cttggctaat
    38461 actattttaa ctaccagcta ccaaaaaggc taaactaaca acaactacat ttttcaacta
    38521 gaaaggccta aacaatgacc aaaaaacagt tttatcttat cttagctatt agcatactgt
    38581 gttttattct tgccgtcagc cctaaaccac caattcctaa acacactatt gaaaggaaaa
    38641 ggactgcgat gaccataggc cactcaaaac aaacccctca caaaaaagaa gcccttaaac
    38701 acaaaaaaaa caaaaataag gctctatttc ttccaagtgg ggacagcgct atcaaatctg
    38761 ttattagcat gacagttaga ctcctgttag atgaccaata ttagctctcc taaaatcagt
    38821 ggacactacc atttcggtag tgttcttttt taagctaatc tcatcaccac gctttcttca
    38881 agctaaaaaa ctgatcatga aagagcaacc ccatcaccct aacagcccac tttgcccgca
    38941 ctttcttaaa aagttaggag aaaacgatat accaattatt ttctgatccc agctccctat
    39001 cattaacaag atgtgtagca cggacctaca tacaggtaag ctagagtcat tctcgctact
    39061 tcggacaaaa agaggccggt agttccctga cctcttcttt atttatcttg taacactcct
    39121 cttcttagcg agacttacta gcacataatt cttaagcact cttatcattt agactaggaa
    39181 taacaccatc tgaatgaagc aaatgatgcg tcagatctgc cagagtatca tctccataag
    39241 taatccctgt ttggtgctgt ttctgatgaa aatcagatga ctccttaact ttagcagtca
    39301 cctgctggtc acttggatga aaattaattt ctctcttggc ttcagccgca actggctcga
    39361 ggaacaactt attgacatta cggtcttcct ccaaatgatt aaggatagca gcatcatctt
    39421 ctaacgaaag aaccttcttg ggtaacaaaa aggggttatt tagccttggc tcagtaacga
    39481 cttccttggc tactcgtgat agtttattat tgtcttcctc aggtatcaaa cggttaggca
    39541 atcgatgcaa ttcttccggc tatgaggcgc tcacagctac ttcagaagaa acctccaagc
    39601 cctttcctgt ttgcctgtct aactaaagca accggcaaat tattaactaa ctttttaacc
    39661 tgtcctcagc gctcatttca acactaggaa gagctgtcgc tggttctagc cagctaccaa
    39721 cttctgctgg tcttacctta acatcgctgg caggcttctc cttctcatct tcattaggtc
    39781 taaaaggctc aaaccgccct gttgattttt catctatgac ctttatattg tcttttacta
    39841 catgagacag tggttcgaca tttaccatag cttcatgctc gttaaggctc tggtctcgtt
    39901 tgaatttacc aggaatacca ggagtcggtg ttccgacaga ttgatcggct tcagtaggct
    39961 cttttacgga gcctttttcc cataacaccg ctgatggaat gatatccgta gagccatctc
    40021 cgtaaataat cgtggcctga ccacctcttg gattaataga taccttaata ttgtctggga
    40081 aagccccact acttcctgtg gttaaaaggg cacccgcatt tttaatgaga gttgtcattc
    40141 gttcaatacc agcaacgcca atatggttca agtcatctac tggtaactga tcaacagatt
    40201 tcatggtgta tttccaagct tgcggttgaa caagaaaaac agttccttta tacattgtgt
    40261 tatgcatatc atcaatgact ttgaaatacc ttgtatattt ggtttgtaca ttagggttag
    40321 caacgggaac agtgctttca ggaactcctg acatcgtaaa aatccctcta gcagaagttt
    40381 gaaagccctc ataaacatga cccataccag gaacagtctg agcggtcaaa gacttaccag
    40441 aaccatccaa agcaatgcga atatctttca tcagatacat ctgattggtg taggtaaacc
    40501 taaccgtgtt agcctcacct cgatacaaaa ccacttggga gggctgatcc gaagaaaact
    40561 gagaggttgt ttcttcctta tagccaactc caaaacgtct atcagacgaa tggactgaat
    40621 ctgccgcaac tgtactactc aaactgacta gtaaagtagc cgcacaacca actaataaac
    40681 tgctcatttt aactttaaca tctcttaaca tcatcatgtt cctttcatta ttttttattt
    40741 aggaattcgt catactatat tttctcatat tagtctaaca aaaaacccgt aattctatat
    40801 aaatcatata aaatgacgag ctttggcaaa gatgagtata gcaggatgga aaacagattg
    40861 tttctgaaac ttcaaaggta tcttcttgtc acgaactatt ctttaattga atcggttaca
    40921 ctaaactagt cccattattt aaaaacaaac tttaaatatg attcatttca ctttttaagt
    40981 ttattaaata tagagtgatt aggaaaaata agacgaccta atgataaaat cattcctatt
    41041 gtatagcaaa caacagtaag gtgtaaataa aagtaaattg atacctctga tatactcgtc
    41101 aaacatccta ttattataat aaaagcaatt aaggtaggaa taagaattgt acacttaata
    41161 aataaccaaa attgcttaac aacttgatac catgtgagca cttctgtcgt ttgtctttgt
    41221 ttgtagacaa aaacgaataa atcaaggata aaactccaac agataagttg tatatttttc
    41281 attaatggta aatcgtagaa actacctata ctaaatagaa tcactgcaga aataataaca
    41341 atacctaaaa atcttaatat attacgcata tcttcacctc ctctactcta tcggtagcaa
    41401 atataaccga acaaattatt attcctgtta tcagagacag ttataacttt tttaaccaat
    41461 tttcaatacg tattttgctt ttaactcttt agtctctaaa g
//
LOCUS       DATWVB010000015        38224 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.015, whole genome shotgun sequence.
ACCESSION   DATWVB010000015 DATWVB010000000
VERSION     DATWVB010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38224
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.015"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(661..1137)
                     /locus_tag="VCX65_000865"
     CDS             complement(661..1137)
                     /locus_tag="VCX65_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEP5053338.1"
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKT
                     WAIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
     gene            complement(1157..2053)
                     /gene="era"
                     /locus_tag="VCX65_000866"
     CDS             complement(1157..2053)
                     /gene="era"
                     /locus_tag="VCX65_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEP5053339.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            complement(2173..2580)
                     /locus_tag="VCX65_000867"
     CDS             complement(2173..2580)
                     /locus_tag="VCX65_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEP5053340.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            complement(2561..3058)
                     /gene="ybeY"
                     /locus_tag="VCX65_000868"
     CDS             complement(2561..3058)
                     /gene="ybeY"
                     /locus_tag="VCX65_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEP5053341.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDFAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(3217..3792)
                     /locus_tag="VCX65_000869"
     CDS             complement(3217..3792)
                     /locus_tag="VCX65_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEP5053342.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARLIIVGQAPGIV
                     AQETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            complement(3838..4890)
                     /locus_tag="VCX65_000870"
     CDS             complement(3838..4890)
                     /locus_tag="VCX65_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEP5053343.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYETSSEEMKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            complement(5049..6821)
                     /locus_tag="VCX65_000871"
     CDS             complement(5049..6821)
                     /locus_tag="VCX65_000871"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEP5053344.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELVHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWIYWATMFAFEKWHSAVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKDNETTVWIYGLYSNSEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLM"
     gene            complement(7136..8317)
                     /locus_tag="VCX65_000872"
     CDS             complement(7136..8317)
                     /locus_tag="VCX65_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEP5053345.1"
                     /translation="MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTQIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATTL
                     TVQAPASSPASVSHVPSSEPLPQASATSQSTIPMAPSATPSDVPTTPLASAKPDSFVT
                     ASSELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEDSTSANRP
                     VPNESASEEASSAAPAQAPAEKEETSQMLTAPAAQKAVADTTSVATSNGLSYAPNHAY
                     NPMNAGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPVSSTLGDQV
                     AQYAIDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFN
                     A"
     gene            complement(8473..8688)
                     /locus_tag="VCX65_000873"
     CDS             complement(8473..8688)
                     /locus_tag="VCX65_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEP5053346.1"
                     /translation="MRKSFYSWLMTQRNPKSNAPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            complement(8685..9194)
                     /gene="msrA"
                     /locus_tag="VCX65_000874"
     CDS             complement(8685..9194)
                     /gene="msrA"
                     /locus_tag="VCX65_000874"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEP5053347.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPEEISYKELVELYWVQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPRRYAQSSAIR
                     HQFLEENWS"
     gene            complement(9267..10124)
                     /locus_tag="VCX65_000875"
     CDS             complement(9267..10124)
                     /locus_tag="VCX65_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEP5053348.1"
                     /translation="MNDLLATVITGLIKEENANDYFIQKEGFTFTLSKAEGERQIGDM
                     VTGFAYTDIKQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYIRLDVDKKDRIWGLPAEPEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKATFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            complement(10233..10790)
                     /gene="frr"
                     /locus_tag="VCX65_000876"
     CDS             complement(10233..10790)
                     /gene="frr"
                     /locus_tag="VCX65_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEP5053349.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAIKEIDRMTAEKEKELLSV"
     gene            complement(10819..11547)
                     /locus_tag="VCX65_000877"
     CDS             complement(10819..11547)
                     /locus_tag="VCX65_000877"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEP5053350.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            complement(11869..12558)
                     /gene="rplA"
                     /locus_tag="VCX65_000878"
     CDS             complement(11869..12558)
                     /gene="rplA"
                     /locus_tag="VCX65_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEP5053351.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            complement(12664..13089)
                     /gene="rplK"
                     /locus_tag="VCX65_000879"
     CDS             complement(12664..13089)
                     /gene="rplK"
                     /locus_tag="VCX65_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEP5053352.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            complement(13556..14836)
                     /locus_tag="VCX65_000880"
     CDS             complement(13556..14836)
                     /locus_tag="VCX65_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISLre2 family transposase"
                     /protein_id="HEP5053353.1"
                     /translation="MRFDENIFVAERNRQCELAFLKQVAAYDKQVASMMRVNGYRRID
                     APERTVLFTFGEMTFSRSRWRKGENTRYPVDEWLGLKPYMRYSPDLIHHMAEHASKLS
                     YREVCRTIETAYGLSVTKDAVLKAVKLAERLLIEKEHYRFLQQVEHPQKIQAERIYLE
                     GDGVMVKTTSGGDERHNTDLAHFLIHTGSRKSGKNRYILQNKHEIINANYDKAREELL
                     DYLYNHFEITDKTILITNSDNGKGYTKRVFQEVKKALGIKYHEHFWDSYHLNKQLKDF
                     FKPYPYVLQDLAFKAIQTHKKSLLETVFDTVETLIETEEESVNYYAFRQKLFRNFRDT
                     RPSQLRGLTSRGIGAMESQHRKVTYRMKHRGMYWSVTGACTMAKIILLERINKLGDLF
                     FGDWRKQYQKYRGRGLGAGHLVNHYPHDAVVIRR"
     gene            complement(15128..15427)
                     /locus_tag="VCX65_000881"
     CDS             complement(15128..15427)
                     /locus_tag="VCX65_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017766841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053354.1"
                     /translation="MANDQNLIPINQRTKSEQRKIQRQGGLASGQVRRQRADLKRAFE
                     TLLTSRVNNEQMKDVLVGLGYDPTNEMALALVVLQRALNGDIKAFSKIQDVIDRD"
     gene            complement(15439..16689)
                     /locus_tag="VCX65_000882"
     CDS             complement(15439..16689)
                     /locus_tag="VCX65_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEP5053355.1"
                     /translation="MQIETLLLSDITPYESNAKKHPKYQIDQIKESIKTFGNNDPIAI
                     DENNVIIEGHGRYLALKSLGYDQVPVIRLKHLSDDQKRAYILAHNKITLNTDFDMQVL
                     KQELTSIMAIDMAQFGFSINLLASPLKGDGEPDFTEDPDSVMEKIGIGSLYQLGRHRL
                     MCGDATKPEHLNRLLEGTKADLYLTDPPYNVAYQGKTSEALTIQNDQMASSDFQAFLT
                     DSFQVVDSHLKAGAAFYIWHADSERLSFSNAISAVGWLEKQCLIWVKDSFVLGRQDYH
                     WQHEPCLYGWKPGAKHYFVSDFSLSTVLASSLEDKSKEELIDLIRAYQEVQTTSILRI
                     KRPQANQDHPTMKPVALLERLIRSSSRQGEVVLDTFAGSGTTLMVCEQLNRINYSMEL
                     DPKYVQRILKRFERETGMKPKQIF"
     gene            complement(16701..18344)
                     /locus_tag="VCX65_000883"
     CDS             complement(16701..18344)
                     /locus_tag="VCX65_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEP5053356.1"
                     /translation="MVVTKVFQIKQTKNLKRAIDYITRDDATLIKVEQHDKDDAFDYT
                     LTADGEVHKKLISGHHLIDPGDRDAIYDDFILLKQSVDELYDNATLSDLKNDNRVLAH
                     HIVQSFSPDDKLTPEEVNEIGRKTALEFTGGDYQFVVATHMDKGFLHNHIIFNTTNEV
                     TLKKFRWQKNTARNLFQISNKHAELYGAQILKPKLRTSYTDYSAWRRQNNFSYEIKQR
                     LNFLLKHSVSVEDFQQKAKALDLHIDFSGKFTKYRLLVPLDGKLQEKNTRDRTLSKKR
                     IYSFEQIQKCVAMNEVVYTVDHIKEKYEEEQAKKAEDFEMKVRIEPWQISEITTQSIH
                     LPVAFGLEQKGTVSIPARLLDQNEDGSFTAYFKKKDYFYFINPDKSTDNRFIQGSTLV
                     KQLSLNSGEVILTKNWEMTELERLVEEFNFLSANKVTNSKQFQEMQERFLEQLEKTDQ
                     TLAQLDSKVAYLNKVLGALSDYQDGLVPSEVTMAILEKAKVAKHTDRNLIRKEIKELQ
                     IEREALQEARDRIVKDYDFANEMEQSYDHKHHQSKGHQR"
     gene            complement(18307..18690)
                     /gene="mobC"
                     /locus_tag="VCX65_000884"
     CDS             complement(18307..18690)
                     /gene="mobC"
                     /locus_tag="VCX65_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEP5053357.1"
                     /translation="MEQKKRKRTIQFILRTKQKEADDLRRRVTLSGKKTFQAYALKML
                     LEGKIETYDYSELRQLRIAVNRIGQNINQLVRYVNTFKEFDQELFTALQEEVKELQQM
                     IVQEFKTKEVAKQHGSDQSLSDQTD"
     gene            complement(19032..19331)
                     /locus_tag="VCX65_000885"
     CDS             complement(19032..19331)
                     /locus_tag="VCX65_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053358.1"
                     /translation="MITEEMMTTTEMILMTYLFEIDEWLKDKKVIQQQQAQLTKEELV
                     TVIKNDLIMLQADQATDYEKELQTTLKTLEALSEAQFQKMKLDLLSWEPTVKHVD"
     gene            complement(19383..22619)
                     /locus_tag="VCX65_000886"
     CDS             complement(19383..22619)
                     /locus_tag="VCX65_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEP5053359.1"
                     /translation="MTNTRDLLSQRFEAQRQKLIAIDIVAVASSLGLNLKQGSGGHLY
                     WDEHDSFHIYPQTNTFRWWSRSMGTNTIDLVQVIQEELTGKKPSFRETVSFLETGQFE
                     SVTVTPVVREPFKHYLAPYEHHDFDLGRQYLKEERGLSDETIDFALASGSMSSATLKK
                     GDYFEPVIIFKSFAEDGRMIGGSLQGIVENKVQHPERGRLKQIMKHSDGLAGFHLDIG
                     KPKRLVFSEAPIDLLSYYELHKESLQNVRLVAMDGVKKGVISRYTADLLTDGQYSQTM
                     PRESIRGAIDAINQTTRILKNNPNLITITVDNDEAGRNFIKELQEDGIPITVDLPPRK
                     EHQSKMDWNNYLKQKKGLLKMPQTEGTQKAPEKVLEHEKMDRSQISSGSLEDDPQGSA
                     KPVSKRDTFEQAVTSHPTFSYPLLQFSTEEAFVSNVRDGYHIASDEDIRNLNYYAPSL
                     QQTANWYRDTLADRQVTYMLKGENEIKALQVSFAKDKFAHLTGIRPIGKGLSAEKLLD
                     DFAEGRGSYPNLTLSNGFNDKIQVLPMIQELSQSKSFVFTDLEEVQKMRNLKASHAIQ
                     SNNRSLVVALKTIDDVTFPSSLLRGKKNLTDDLIQKAKENEVLGVLSEKDGNISVLSV
                     NDKYIQDGGQVLKDMIINGEFEPLQMVTMQRNVPYDNAYPKDSDGDGLTDDEEIALGT
                     NPFSSDSDGDGTPDNVEKANGTDPTNASDNEVTRQQEANKRDFTLSEMIKAKNTAALN
                     QHLQDGIKQYFNSDTYKQYLEGMAHFNNYSPRNIQLIMSQFPEASMVASFQEWRKRNG
                     SVKKGEKAIYIQAPVSVMKKDENGKPILNPETGEKETVTYFKPVPVFDIKQVSPQEGK
                     ELNLPKAMGTIPEQLDKDYYQNVYRSLRDISQNNNKVPIRFRELGREDGFYSPQTNEI
                     VIKKGMSYERTLSTLIHEMAHSELHNKQSLTERFDGKLTRSTKELQAESIAYVVSNHL
                     GFDTSQESFPYLASWSREKDGLANLTAQLEIVQEEAKSLMERIDQQLSQYQTVTLNKE
                     TQQLTKQEMKKQSHPFYQSLAAAKTSRTQVTTHEKEASVKKDNRPTMP"
     gene            complement(22621..22986)
                     /locus_tag="VCX65_000887"
     CDS             complement(22621..22986)
                     /locus_tag="VCX65_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053360.1"
                     /translation="MTPQTLRRLDVKKQFIETIEPFAHRQTLKPKAVNSSKTTMSIQR
                     YNHWGTKIQLRIGYSKVLIRIFSNGKINLTHYDLFFDHEETLEITDAFDNGVYTQDEV
                     DGFIKQAKTFIKQALKGEV"
     gene            complement(23028..25073)
                     /locus_tag="VCX65_000888"
     CDS             complement(23028..25073)
                     /locus_tag="VCX65_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEP5053361.1"
                     /translation="MELKRKRLLPYLLLSLLLAYLTHRAYVLYCMAPQADMTNLFAPY
                     TYVFEKITEPPYFYWNTSPLALLSALVGFFVGLLFYLKIRLDGNYRHGEESGSACFAT
                     AQELKGFQDEEPRNNMIFSREAQMGLFNKRLPFERQLNKNVLVAGLPGDGKTYTYVKP
                     NLMQMNSSFIVTDPKGLLVREVGTLLKENGYQIKIFDLVNLTNSDMFNPFRYMRSELD
                     IDRITEAIVEGTKKGDREGEDFWNQAKLLLNRALLGYLYFDSQVRHYEPNLSMVADLL
                     RNLKRPNEKELSAVEKMFKQLEEKLPGNYACRQWELFNSNFEAETRTSVLAIVATQYS
                     IFDHDAVTNLIKTDTMEMDTWNTEKTAVFVAISETNKAYSFLASTFFTVVFDQLTHSA
                     DAIIQGQKKGYELKDLLHVQFYFDEFANCGKIPHFNEVLASIRSREMSIKIIIQAISQ
                     LDSLYGVPARKSMINNCATLLFLGTNDEDTMKYFSMRAGKQTITQTSYSEQRGQRRTG
                     TTSRQAHQRDLMTPDEIARIGVDEALVFISKQNVFRDKKAMVSNHPMKDRLANHYQDK
                     TWYHYKRFMEEGAEFIDAVMTGQIPEDHVWAPDMSGYQAFLVENGFDNTRQSAPETSA
                     RDQVPITNPEMPSESLSQTPKTSTKLVDMDTGEIFELPPEDREGFGEVSFDDQRVEI"
     gene            complement(25073..25564)
                     /locus_tag="VCX65_000889"
     CDS             complement(25073..25564)
                     /locus_tag="VCX65_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3801 domain-containing protein"
                     /protein_id="HEP5053362.1"
                     /translation="MDQERVMEKGSRVTLETGKHLLQFLAYAVSQGAKTYKEHKQSGE
                     MSWKDFNQLPRTKDHIDFEEAEVNLEKLRKELKKSGVNFHFKKNGDGTKQVWFEAINQ
                     QVIQEALRKINQEIVSNPKEALDKYMKKPDELTPKQQIEKLKKTSKKSTEAVKTKKKG
                     KGI"
     gene            complement(25586..26368)
                     /locus_tag="VCX65_000890"
     CDS             complement(25586..26368)
                     /locus_tag="VCX65_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053363.1"
                     /translation="MFRIQNQSDGKEQEFQNLAALLYALEGEEKRCLQLNMRATFYLF
                     HLDKNEEVLESMELTIPAQEDKEVQELIGEFGRKGDAKKPFWKRSESKQQPQAINSSN
                     SNDSQSKTGVSKLVKGLMWLLPMVLSVVSIYLSLETLQLVKTQPQVTPKVETVVINQK
                     ADVFCRYFISSYFSQSLNLEDYLSEKLSKEDLKINKATPVSVLLENQEIKGNTTLVTY
                     VVNIKEAQDHVSSKRLTLAVRADKKAQYGYLVIKKPRLTAYP"
     gene            complement(26368..26640)
                     /locus_tag="VCX65_000891"
     CDS             complement(26368..26640)
                     /locus_tag="VCX65_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017794861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053364.1"
                     /translation="MTNEEYINQTSSSKSRRQKSTQERLDDKIKQLEKAQESQDALQK
                     KIKTLKDDITILEGKRQQEIMAEYGIDLHGLEAILATYKEERGGEG"
     gene            complement(26663..27265)
                     /locus_tag="VCX65_000892"
     CDS             complement(26663..27265)
                     /locus_tag="VCX65_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053365.1"
                     /translation="MIDTVKVTYFKRAIGIVCLILIFCIGFGFGQMGKNSQDSSETKV
                     STINKSDDKRLNESLVKKFLIAYYTKKDLEENRQRYKEYMTEGLYNATVSEENKAQSQ
                     TYKGYIINYAFESAQIYIDHINHQVICKVTYTNDLLKEKNNAEGAQKGVVNHTTIQLD
                     YAKVNGNFLVNHMSTLLLTDSSDLTESEAAYGAITPSETD"
     gene            complement(27289..29985)
                     /locus_tag="VCX65_000893"
     CDS             complement(27289..29985)
                     /locus_tag="VCX65_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP5053366.1"
                     /translation="MTEEKQDLRSRVVRKRQIKASVHRHNQASARKAQKAAKGELQVA
                     TKELKEAREAYQKAQTDFRAGIIDDEALKKAQEKLKQAKAKYKDAKKVKKKVRKTNPT
                     LSQKARQTGRRITKRKGQEILEMGFEQDDTLSDLVRAKHQIRQTQAMAKQAGRATGKG
                     IKLTYRGAKGTVKLGAKGTKYAYHQTRKGSVKATQETVKVASKTAQTLVATSKALVSA
                     ITPIIANPITWVVTGVISLLLLIVILVSSVFSSNVVQQNEFTLNQSWLHISKVDRQKS
                     SDKVDYYTDIDSILLYMNYRYGGEWEPDAKWDDGFGGKVTGALGFNHFSDALDDIWKE
                     ENQDIDHLKTMAELYTNGKEWIKFSKDDLEEYKEILDSQAETGKFLAYQELSNPFYSS
                     NDDKADSEYLTVTKRYGYTDKATIDPTTTLQAKASQKLYAVMDGKIAVTTKDLKGEKT
                     KTTNLIIEDKEARFIYYDVSNSRVKTGDKVETGQELATISGSTQKIAYAKRYGEVDDK
                     DAAWLKNIRDREVSYGYMIQTKKDKKEVWVLTNPGFYFPFVKYAETTIVTQTPSEMSG
                     RAKQFYDLVKKYLPQATDNGIAAIVGCFGVESGINPKRAEGDYLSPPVGASDSSWDDE
                     SWLTLGGPAIYGGGYPNILHRGLGLGQWTDTSDGANRNTLLRAYAKRKGKKWYSLELQ
                     VQFMLEGDNPYYINIFKQIATGHSDLNSLTAEFLAKWEGVPGNKLAQRQAIAKQALSW
                     FKYPNIVGGGTLASSYNFPEEYRSRFPNPPTQRAMTTQAGNGYPVGQCTWYSYNRLVE
                     LGSITDLSGSYGYLGNGQNWVASLVAKGWRYSPTPIKGAVVSTAGGFDGTFPQWGHVG
                     IVEVVNPDGSFLVSELNYGGIQHKIHYRVCRPAPFYSFATPK"
     gene            complement(30025..32373)
                     /locus_tag="VCX65_000894"
     CDS             complement(30025..32373)
                     /locus_tag="VCX65_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEP5053367.1"
                     /translation="MTLTKTEKERAKQLQRALKASTQNTIQYTSLFEDGLMHIVDETY
                     SKSWQLGDTNYITGSEDEKLDIIEYYVDALNGLDSENTYQLTILNRPVPTTLLDQITY
                     DLEGDERDIFRKEYNNIIRSRFAKDQNNFKVEKFVTVSTRAKDRKQAYRKLNDVDTHF
                     TTQFQLVDVLLKSLDGTERLNIFADLLRGNPYLDVDYKDVRISGLSTKSFIAPGRLWF
                     KPDQFMMDKKYCKILFARTFPAFLNDRLIKSLTDIGIELAISIHAQPYDVAEAVKKVN
                     IAEAGVKMDMVKSQVSAAQKGISSNLAVSSVAQDTADEAEKWKAEINDNDQKMFSGVF
                     LIMVKADSAEELADYTSRIKQAGRKHVIEFEETYYHQEEALNSMLPIGKTYIDVKRRF
                     MRDMTTTNIATQIPFTNTDLQSQSPLANYYGQNQISNNIISLDRQRDLYTSSGVILGS
                     SGSGKSVFVKINEVIPAILRFPNDRVIIVDPEEEYVDIGHAFGAQVIDIYPGTKTHFN
                     LMDIPDLDKLRDEDKDFVGQKASLIMGLFENILQEVTDDDVSLIDRVTRLCYEQITDR
                     TPTLKDWHDILLEQPEEEAQSLALKSESYTKGSQDIFAYETNVDLNNQVVIFNLKKLS
                     GKLKPFAMMVIQDYIWQHVVDHKDEFVTRVYFDEMQNQFETDDQAAFFSKMYARIRKY
                     GSIPTGITQNVETLLSRKEGRNLLYNSEFLVLLKQKKTTIPYLLKTINLTDALVRYIE
                     KPKAIGTGLIIAGTTTVPFENPIPEDTELFRLVATDAYRKME"
     gene            complement(32354..32713)
                     /locus_tag="VCX65_000895"
     CDS             complement(32354..32713)
                     /locus_tag="VCX65_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEP5053368.1"
                     /translation="MNKLGSEFFKAIDQFERGVIGGATWRQVVMVLGIVLGVGFATVI
                     SLLQLPIILFYLSLVLTVPPAFIYGIKKDEHIKEVITFRLKVQERAYQTEYESEEIHG
                     AFIPQKGVQEWNDPNEN"
     gene            complement(32761..33339)
                     /locus_tag="VCX65_000896"
     CDS             complement(32761..33339)
                     /locus_tag="VCX65_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053369.1"
                     /translation="MISTYDRQLRTLKRENKALKKQLAYFEEFNQNNRQLLYCQTVKG
                     IYMLASVSYSLDHLKRINRLEFKVNDTFKHRRKDRLNFLNVEAYYHDKDRDKSGTLNY
                     LLIRDFLMVPPNKGYGSFLLREALFHISQLFGEKVRIIGKLSHVDERDPENHARRDYV
                     YQKFGFERRDHRIQMTTIPLEILTKEREKYNK"
     gene            complement(33323..33781)
                     /locus_tag="VCX65_000897"
     CDS             complement(33323..33781)
                     /locus_tag="VCX65_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053370.1"
                     /translation="MINQGQEYQYFKDKISHLESEVSRLSSYEYEHRLLRDVIADCLL
                     QGQLTVSELPQAIRLIQGDDLFYTYAWRFVEATGDCQAGITILKILQDDLNYFFAIGK
                     LSQKQYSQWLEKWLSFLERGRIAFKGEKDFERYFQDQTEANRSLFNDFNL"
     gene            complement(33800..34069)
                     /locus_tag="VCX65_000898"
     CDS             complement(33800..34069)
                     /locus_tag="VCX65_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053371.1"
                     /translation="MNLEKLKQRRDELIRDNEWMDGLIKEKEDELWELKVRSIAASEL
                     ARSAMQSAMRTAGIVDSFYGPSTQSSDNQTNKSVEADHNKSCFLC"
     gene            complement(34106..34858)
                     /locus_tag="VCX65_000899"
     CDS             complement(34106..34858)
                     /locus_tag="VCX65_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053372.1"
                     /translation="MKDILSELTKELGSYNSSVNRSMTAVNKSLMAIGYILVSILFLL
                     ELLSWYRFIRNQGGEMTWKLFLEVAVKYFIAYFLVSQSGAILNAILWFTNGVTKLIGV
                     DLSGDNMFEFVWLKKGNLGVRILVNGLAAIAGVGAMISIKVMVLLRFIELYFYKAIAP
                     VIVAFWMGDDTRYIAKNFLKTFGAIALQSAVIVLLLAIWQGLNIDAVIKISKDSWVGA
                     FAAGFSYIGKCIVFLILLFGSQRKAKQLLQVS"
     gene            complement(34909..35478)
                     /locus_tag="VCX65_000900"
     CDS             complement(34909..35478)
                     /locus_tag="VCX65_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017794872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053373.1"
                     /translation="MAESFDYVAFARDFEKRHGRPPTAEELEQGIDPWEGIVTFHTPE
                     ETQAEIERINASYKPSLWERLKTGLSFVIRNFFRALLILIQTPVYLTLFFFNLIKSTI
                     GVFVIWFISKFVLGWLVGIIAGLIYGFDLYKNPFPSPIKDIVDFSFGVNFFEDAVPNF
                     FPHPVADAWIIGITIVFLALVMTFSKSEA"
     gene            complement(35583..35810)
                     /locus_tag="VCX65_000901"
     CDS             complement(35583..35810)
                     /locus_tag="VCX65_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053374.1"
                     /translation="METAVRVVTAMGAILAIVGLGWVLTGAFDYFAGRKNGSPQMMDQ
                     GFTSMISGGALAVIAAGVAAAIVAAMRAISF"
     gene            complement(36108..38114)
                     /locus_tag="VCX65_000902"
     CDS             complement(36108..38114)
                     /locus_tag="VCX65_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP5053375.1"
                     /translation="MVTPKVEQEKPVPEAPQKPTDGVPNLEKEKPVPPTPVKPEAVKP
                     VLEPEKPVPEAPQKPTDDVPNLEKEKPVPPTPVEPEAIKPDLKSFTPEIYNPIKSVVK
                     PHVTVPEKVVYEVMVHPVQVKQTPTNVKSVTNSDQVNIDGQLVPKGSTVTWELVNTSL
                     KAGRQDITSYELTDPLPDGFELDVTATQALSPEWVITTDEAGKVSLKASQSLLAHFNA
                     KRDQDVEVPKVSLVGRLLNDAGTYHNTFKTVVTTPTGSYTVISNTPVIYTPGNDPKTP
                     RNPGGDNPTPHDNLIQPTKTIVDDKGQSIDGKSVLPNSTLTYVAKQDFDQYKGMTAAK
                     ESVMKGFIYVDDYKDEAIDGHSLVVNSIKAANGDDVTNLLEMRHVLSQDTLDDKLKAL
                     IKASGISPVGEFYMWVAKDPAAFYKAYVQKGLDITYNLSFKLKQEFKKGDITNQTYQI
                     DFGNGYYGNIVVNHLSELTVHKDVLDKEGGQSINAGTVKVGDEVTYRLEGWVVPTNRG
                     YDLTEYKFVDQLQHTHDLYQKDKVLATVDMTLSDGSVITKGTDLAKYTETVYNKETGH
                     YELAFKQDFLAKVVRSSEFGADAFVVVKRIKAGDVANEYTLYVNGNPVKSNKVTTHTP
                     EQPQPVTPKAPALPSTGEQGVSVLTVLGAALLSLLGYVGLKKRQ"
BASE COUNT        10589 a         8097 c         7044 g        12494 t
ORIGIN      
        1 ttttaggata tatgatatct atctatatta actattacct caagagatac tttctaaaaa
       61 ctcaaattat tagtgggaaa aacttagatt ataaatacaa atgtcaggtt tattttatca
      121 taaatcatac ttttttaaat ctgagcaagt atatgacctt ctaaacgaaa tacgtatgcg
      181 ttatcctcat gctcatatta ttctaatcgg aaatcatatt aattacgagg aaatatttaa
      241 aaatcattat cgagtttttg gtgttattga cacaacaagt cataaatcat taaagtccat
      301 tcgagatcaa attcaacttt acttagacga actttacaat tcgaataatg gataggcact
      361 tcatcaattc ttttaggaaa tgattcttgt caccccttcc aagtctattg ccacagttag
      421 gttcaacttg cctaagtcat gcatggctag gtggcaattc gtcataactc taaaacaaat
      481 gtttgatgtc tgctagtatc aattggaaag aaaatcctgt taacatttaa caaaattatt
      541 cagacttaat cagaaaaatt ggaagcaaaa aaagagagca taagctctcg aaacatcgtc
      601 tttcaaaaat ttttttaaca agccaatctc caaaaatact ccaactgtcc tagagagttc
      661 ttaatgcccc atagcaaagc tatcactaaa atattcctct aacatcaggc gatgtttggc
      721 tgagacactc tctaactctg ctatctcctc atgagagaaa aactgtaact tgagcgtttc
      781 ctcattatga aagttatcaa tagccatatc agaaacagcc gttagttcat agataaagac
      841 aatagtctga acagcatcac cgttgggata aacttcctca aaatgagtgt aaacattcag
      901 taagcgaaca gcttcaacct caattccggt ttcctctaag aactcacgtt tgcaagtctc
      961 taaagagctc tcacccagtt ccatagtacc accaggaata gcccaggttt tcttatcacc
     1021 acgcaactgc atcagcacct tgccgtcatc attggtcaaa atcccaccag caaagttaag
     1081 aataatctta tcatgcccaa ctttggagcg gatataagaa atgtagtctt gtggcatatg
     1141 atctcgcttt actatgttag tattctttct cattatagcc aaaatcagct aaatcaagct
     1201 ttttatcccg ccagtttttc ttgactttga cccacgtttc taagtagacc ttgtcaccta
     1261 acatgagttc aatatcacgg cgcgccattt ttccgatttt tttgagcatg gctccttgtt
     1321 ttccaatgat gatgcctttt tggctatcgc gctccaccat aatggttgca cggatatgca
     1381 ctttatcagt ctcttcatct cgcttcatgg attcgacaac aacagctacg gaatgtggaa
     1441 cctcttgttg cgtcaaatgc agtaccttct cacgaaccat ttctgacaca aggaaacgtt
     1501 ctggatgatc agtaatctga tcttctggaa aatattggaa accttcttca agattatcag
     1561 ttaataactt gattagggtt ggcacattat taccttctag ggcagaaatt gggaccactt
     1621 ctttaaaatc catttggcta cggaagtcat caatctgttc caaaagttgg tctggatgaa
     1681 ccttatcaat tttgttgata actaaaataa caggaatctt agctgctttt agccgctcga
     1741 taatcatgtc gtcaccctta ccacgctttt catcggcagg aaccatgaaa agaaccgtct
     1801 caacttcacg taaagtacta taagcagatt caaccataaa atcaccaagg gcggtctttg
     1861 gtttatgaat acctggcgta tcaataaaga caatttgttc tgtttctgtg gtgtaaatgc
     1921 ccataatttt attacgggtg gtctgagcct tgtcactcat gatggcaatt ttttgcccca
     1981 tgacgtgatt taaaaaggtg gatttgccaa catttggacg accaagaatg gctacaaagc
     2041 ctgatttaaa catagataat tacgggcctt aacggtaggg cttcagatca agcttgtcac
     2101 taagcttaac cgtcttgtcc tttccttatt ctcctatgcc atcatcacat aggatagccc
     2161 attcctttct ttttaatgaa cgaaaatatt ccaaatttta ggaataaaaa taataagtcc
     2221 tgtcaagaca gcatagccag aaatcatcaa aacagcacct gctgccatat ccttggcatt
     2281 tttagctagc atagaaaagt gatagtcact agccaaatca actacatttt caatagcaga
     2341 attgacaatt tctaaggtaa tgaccaaaaa aatggctaga agtaaaaata accattcgat
     2401 ggctgaaatg ctaaaaaata aaccagcaac acaagctaaa caggcagaca aaaggtgact
     2461 tctgagattg cgttcttcct taaaagctgt gaaaacccct gtcaaggcaa actccaggct
     2521 tgaggtaatg gttctgtttt tccatttccg tttggtggta ttattgtcgt gtaaggccat
     2581 aagcagtcaa aatctcttcc tgtaaggtaa acatctcttt ttcttcttca agggtgtagt
     2641 gatcataccc attaatatgt aagaatccat gaacagctaa aaatcccatt tcacgctcaa
     2701 aagagtgccc atattcttgg gactgctcac gcgccttgtc aatagaaata aacaattcgc
     2761 caatataagc atcaaactct gccatcatct ctgccaaact aggatcagca gcaaaatcct
     2821 cttgactaaa taaaataggc gtttctggct tatattctag agaaatcaca tctgttggac
     2881 gatcagtatc tcggtattct aagttgagtt catgacttct ttcattggtc acaaaggtca
     2941 cagacatttc tttttcttct ttgcccgtct tttgagcagc aaaattgagc aaatcaagtg
     3001 tttgctccat aatctcttgc gaaacttgtc ccgtttcgtc aatcatctcg atatacataa
     3061 ggttaattgt tagggaaggg ctgcccacct catttggtat gttgggcacc cattattatc
     3121 tgacagataa tttcccttat cctttcaatc agcatttgtt atttacccat tataccacaa
     3181 gcccctaaaa aatgggaatg ctaggtaaat cagggcctat ttggttagaa ttgcctccac
     3241 acgtttttgc aagataggta ataaatcctg ctcaaaccag gggttcttag ctaaccacaa
     3301 ttggtttctt ggagaaggat gaacaagtgg aaaatagtct ggcaagtaat cctcaaagtg
     3361 acggactgtt tcagttaagg ttttgtaagc cttgttacca aggtaaaagt cctgagcata
     3421 gcgaccaacc aaaatcgtca attcaacttc tggcatcaat gctcttaatg gcgggtgcca
     3481 cttagccgca aaaccttctc taggtggtaa gtcaccggat tttcccttac caggataata
     3541 gaaatccata gggataatgc caaacaatcc tgagtggtaa aaggtgtcat tgtccacacc
     3601 tagccagtct cgtaagcgga tgccactacg atcattccag taaagtttgg tttcttgagc
     3661 tactattcca ggagcttggc caacaataat aagcctagct gtttgaggag catcatataa
     3721 aggaaaaata cctctttcgg tataggagag attagcctca tctgccataa tagctttggt
     3781 taaatcatcc atagaatcct ccttaaaaag gccatattaa acatcatcgt aaaaatctta
     3841 gtgctcttga ccaatcacag ggtattttgt caagcctggc tggtaatcag cttcaacgtc
     3901 actagcctta ggttttagta agtccttcat ctcctctgag gacgtttcat aagccttgat
     3961 aatatcagcc acaacaggat gtcggacaac atccttagca gagaaataga caaaatcaat
     4021 ctgtttaatg ccttgtaatt tctgagtagc atcaatcaaa ccagacttga catttcgagg
     4081 gaggtcaatc tgactcgtat ctccattgac aatcatttta gaattaaaac caagacgggt
     4141 caaaaacatc ttcatttgca tgatggtcgt gttttgagcc tcatctaaga taacaaaagc
     4201 gtcatccaga gtacgacccc gcatataagc taacggagca atctcaatca catctcgttc
     4261 catcaggcgt gtggtttgtt ccttgcctaa aatgtgataa agggcatcgt aaacaggtct
     4321 gaggtaagga tccacctttt ctttcaaatc gcctggtaaa aaacctaggc tttcaccagc
     4381 ttctaccgca ggacgcgtca aaataatacg ctttacctgt cctcttttca gagcagtgac
     4441 tgcaagcgta acagctaaga aggttttccc tgtccctgca ggtcctacac caaaaaccac
     4501 atcatgacgt ttgacactat caacataggt tttttgacct aatgttttga ctcgtattgc
     4561 cttaccatag ttatctttaa tgatttcttc ttcataaagc gccataaatt ggtcaatctg
     4621 atgagattct gccatagata aagctgtcac cacatctgat gtgttgacca ccatgccacg
     4681 acccactaga accagtaggg ctttgatggt caatcgagcc aattccacag cttcttcatc
     4741 atcaccaatc acttggactc gctcggttct tgcgtgaaca ataactccta aatgagcttc
     4801 tattagcttc aaatgacgct cgttgctacc aaaaagagct aaaacatcat caggatgggt
     4861 taaggtaatg tcaatagaat actcttgcaa atagagtccc tctttctttc atctttattg
     4921 cttacattat aacaaatttt aaattcttat gtgacgttca cgtcagactt ttcctttatc
     4981 acttttctat aaatcatcaa aaaagctgat aagcctaaac ttatcagctt taactactct
     5041 aaggcatgtt acataagatt agcatctttg agcaattctt cgataaaggt atccttgatt
     5101 tttttatgtc cgattttctc aatcagtgca ggaattggca aatccatatc cttgattgcc
     5161 tttttatcat taaggtaata aaaggctttg agcaattcac gaatatcata ggctgaatta
     5221 aagacttctg gaatgcctcg ttccacattc aagaagctat acactgcttc catggcagta
     5281 cgaatagaat actcagtcgt aaagaccgta tctcgagatg gagattccgc aaagttacca
     5341 ataaaggcca agttgactga accatctggg ataactttcg gacggtctcc tttgacacgt
     5401 ggcataaagt aactcgtaat ataaggcatg taaacaggaa ctgtattgat atagtcctga
     5461 ctcgctaagt ccttgatttt atcaacaggt accccaaggt ggtacaacca ttcttctgtg
     5521 atttcttgac ctgtacactc ctcaattttc ttgtggacgt aattgccctc actattggaa
     5581 taaagaccgt aaatccagac agtggtttca ttatcttttt gttctttaaa atgaggttga
     5641 cggtgaatgg caaagctcat catccagtta gaatctgtaa tagtgatgat gccgccagtg
     5701 ttcactttgc catcgtgcaa atcacggtgg gtcaaacgtt caatataagg ctcgatagct
     5761 gggtgtttta tggttgctgt ggcagacaca aaccagcttt cagcaggcaa gtcctggtaa
     5821 aacactttag gatgaccaaa atcatctgat tgagcagcta gattttccca taaattccaa
     5881 gaaccaccta acgctttggt tggcttagcc acttcgtgat gactaccgta tgtgctactt
     5941 tcagtaatag aaccattggt cacaaaaacc aaatcatcag gtgttagctc aatcgcctta
     6001 gcctccccag acaccgtcat atggatggtt tttgctacct ttttaccagc tgtttgttcc
     6061 acctgaatat cagtgacttt tgtgtcaaat tggatgtcaa cgtcgtgtga ttctaggtaa
     6121 gcaataatcg gtttgaccat agaatcatat tggttatatt tgttgaactt gagagaggtg
     6181 aaatctggca aaccatcaat atggtggata aacctcatcg catagcgccg catttctaca
     6241 gcagaatgcc atttttcaaa agcaaacatg gttgcccaat agatccaaaa attactctta
     6301 aagaaatctt ctgagaagaa ctcttcaatg gtttgatctc ctagagattc ttctgtcttc
     6361 atgattaaat ggactaattc ttttgactgt ttaccgagcg tatactggcc gtcatcatcc
     6421 acacgatttc ctctcttgtg aatcaaacga cagttggatg agttaggatc atccttatcc
     6481 aaccaataaa attcatccaa ataagacgca ccaggaattt ccagtgaggg aatagaccga
     6541 tacatgtccc acatacactc aaaatgattt tccatctcac gaccaccacg ggtcacaaaa
     6601 ccaagatgag gcttttcaat accatctaaa gaaccacctg ctaaaggcaa ttcctcaaac
     6661 agatgaatgc gttccccagc catatgccca tcgcgaataa ggaaaacagc tgctgctaaa
     6721 ccagctaaac cagtaccaac aatataagcc gatttctgat ctaccccttc aggttttcga
     6781 ggtgtcgcaa aagcttcgta attaccacta gtataataca tttcaagacc tccttgaata
     6841 gtcaagcaaa gtgatatcat cactccaaag gtaagggcag attgctcagt tgtcacgaaa
     6901 taataggtat tcttctacct ttatcatgat catatcaggt taattatcta tattttaccc
     6961 ctaaacccat atttgcgcta ataaaaacca tctcttttag acataacgtt aaaactgtct
     7021 aaagggcgag aaaaacaaca ggtattaaaa gcgtatctca gcctcttata gggcttactc
     7081 tgtcagaatt gtcaaaaaac tcacgcctaa acgtgagttt ttttgatagc atgaattaag
     7141 cattaaagga gacatgaaca tgatcataat ggttttctgt aatactgccg cgatctggca
     7201 tggggttcca tgtgtaggct ggtccgtaaa tacttgcaaa tggcgcatag aatcgctgtt
     7261 tccaaataac gtatgaaata ccacgctctg ccatatggtc aatggcatat tgagcaactt
     7321 gatcaccaag cgtagagcta accggtacca taaagtcaat ggctaatcct ttaccatgat
     7381 ctcctggatc tcctggacgg taaccactaa atgacgtaat accaaaggca gaagccactt
     7441 cttctttgaa ggctgctgtt tgtggttgaa gccctgcatt cattggattg taggcatggt
     7501 ttggagcgta agaaaggccg tttgaggttg caacacttgt ggtgtcagct acagcttttt
     7561 gtgctgctgg cgcagttaac atctgagagg tttcttcttt ttctgctgga gcttgtgctg
     7621 gggccgcaga agaagcttct tctgaagcac tctcgttagg tacaggccta ttagctgaag
     7681 ttgaatcttc tgagatgtct gtcttaggtt cgacttcagt cgtttcagct gctttaggag
     7741 ttggaactgc ttcttgtggt acttctggct gcttttgtga ttcgctagac aactcagtcg
     7801 aaacatcatt cgttgatgat gtgagctcag atgacgctgt cacaaaacta tctggctttg
     7861 cagatgctaa tggtgtcgtt gggacatcag atggtgtcgc agatggtgcc ataggaatag
     7921 tcgattgaga ggtggcagat gcttggggta atggctcact gctaggtaca tgactaacgc
     7981 tagctggact agaagcaggc gcttgaaccg tcaaagtcgt tgcctgaccg tgttggttgt
     8041 agtttgctgt taggatcgtg tctggaaaaa ttaagtcaat attagcaata tgattaatat
     8101 ctcctaagac atgcacatca atccccattg cttcagcaat tgtgcttaaa gtgtcaccgt
     8161 attttactgt ataagtaaaa acattatcaa ctaggacgag ttcagacttg atttgtgtaa
     8221 ccgatcgtgg tgtccactct tgtgcctgcg ctgtcgccaa aggtgctaac gacaaagcga
     8281 cacttgtcac aaataaactc tttttagtaa taatcatctc tgcttccttt ttattttttt
     8341 ctaagctata tcatagcata tttttaagaa aaaaagtagc ttgtcatttt tttgaaagaa
     8401 agtgatgtca ttttgtaata ataacgtgat aacccttcaa aagagtcgat atgactcttt
     8461 cttatccacg tattaatgtg ctagataatc ttcccagatt tcatcaaatt gacctaaatt
     8521 aaaggaaaaa ctagcttgat cttctagata ccgactaatg agttcaaaat cattggtatg
     8581 ctttggaaaa gtggtgtcat caaacaccaa atctgctaaa atcgccacag gtgcatttga
     8641 tttagggtta cgttgtgtca tcagccagct gtaaaatgat tttctcatga ccaattctcc
     8701 tctaaaaact gatgacgaat agcactgctt tgtgcatacc gcctgggatt ctttttataa
     8761 aatccttggt gataatcctc tgcgagataa aatggctctg ctggttcaat agtggtgaca
     8821 atgggttggt caaaacgtcc tgaagcttgc aagtttgctt ttgattgctc tgcaatttct
     8881 ttttgtcttt ctgttgtgta gtaaatgaca ggacggtagt tgtccccacg atcttcaaat
     8941 tgcccaaagg cgtctgttgg atccgtctgc acccaataca attcaactaa ttccttatag
     9001 ctgatctctt cagggtcaaa aataatttca acagcttctg tatgtcctgt tgttttggca
     9061 caaacttgtt catagctagg atttgggaga tgcccacctg tgtagccact tctgactgac
     9121 aaaatacctg cttgctcctc aaaaggttgc accatacacc agaaacaacc tcctgcaaaa
     9181 atggctcttt ccattctcta tatccccttt ttcttcactt aatggtcttc attgtaacaa
     9241 aaaactttgc cagtggcaaa gcatttttat cctattaatt cagttcctgt ggcgtcttgt
     9301 ttgatgcgtt tagctttcat caatccaccc aaggcttttt taaactggcc ttttgaaata
     9361 ccaaaggttg ctttaatctc ttctggactt gatttgtcat ttaaggtcat gaagccacca
     9421 ttggcttcaa gataagtgac aatcatctga gcgtcattct ccaacatctc aaaagaacgt
     9481 ggtttcaacg acaagtttag ggtacgatcg acctctctaa acccaatcac acgggcatct
     9541 aaaacctgac ctaagcgcgg ttctgcgtag cgttcacttg ggtgaataaa gcctaacatg
     9601 ttgttttcag gcaggtaaac aaacgttcct gttaatttta ggcggtaaac aattgctggc
     9661 caatgttgat tttgcatatt attgtatgca gggctagcca tcttttgaaa gacctcaggc
     9721 tctgctggaa gtccccaaat acggtctttt ttatccacat ccaaacgaat gtaaagttta
     9781 tccccttttt taggccatag ttctttcatt tcaggcaaca cgtccaaaga aaccacaatt
     9841 tctttatttg gaattcctgt atcgacaaaa acgcctaggt cacgacgaac ctctgtcact
     9901 tccccccagc cataacttgt ccgtgttgaa cggatctctt tggttgtgag acgtgccttt
     9961 tgctttatgt ctgtataggc aaagcctgtg accatatcac caatctggcg ttctccttct
    10021 gctttagaca aggtaaaggt aaacccctct ttttggataa aatagtcatt agcgttttct
    10081 tctttaataa gcccagtaat gactgttgct agtaaatcat tcatatcttt tttctttctt
    10141 taaaaaaata gggacaaatc aaaaccaaac gcttctgaaa tggtcaccta tctttttgtg
    10201 tctatagtcg tctatttttc gtagaaatcc tgttacactg agagcaattc tttttctttt
    10261 tcagccgtca tgcggtcaat ttctttgata gcatcatcgg ttactttttg gatatctttc
    10321 tcaagtgttt ttaactcatc ttcagtgatt tcttttgctt tttcttgctt tttagcatca
    10381 tccatagcat cacggcggat attacggatt gcaattttag cattttcacc aacttttttc
    10441 acttctttgg ctaattcttt acgtgtttct tcggtcaaag ctggaataac caaacgaatg
    10501 acagagccat cgttagcagg tgtaatgcct aaatctgatg cgttaagagc gcgctcgata
    10561 tctttgatag aagatttatc aaaaggcgag atcaataaga cacgcgcttc tggcacagtg
    10621 attgaagcca attgatttaa tggcgtcggt gccccgtaat aatcaacttg gatacggtct
    10681 aaaagactag cgttggcacg acccgcacga atgctggcat attcacgtga taaagactga
    10741 tgggattgtg caaaacgttc ttttgcagtt tcaataattg catttgccat gataattact
    10801 ctctttcttt tctaactttt agtcacaaac tttatttgat acagtagttc caatatgttc
    10861 tccaaagaca acacgttgaa tattgccagc ttcattcata ttgaaaacca ccagatcaat
    10921 atcgttgtcc atcgataagg tcgatgccgt tgcatccatg attttgagac cacgtttgat
    10981 cacttcacca tgtgttaatt catcaaattt aaccgcatta gcatcttttt taggatcagc
    11041 attatagacc ccatccacac cattttttgc cattaaaata gcatctgctt caatctcagc
    11101 agcacgcagt gccgcggtgg tgtctgttga aaaataaggc gagccaatac cagctccaaa
    11161 aacaacaatc cgattttttt ctagatggcg caaggcacgt ccgcgaatat aaggttctgc
    11221 tacattttgc ataggaatag ctgtttgcac acgggtatca acaccataat gttgaagact
    11281 atcagccatg actagggcat tcatcaccgt tccaagcatg ccagtgtaat cagcctgaac
    11341 acggtccatt ccagcgtctg ctgcaggctc tccacgccag agattgcctc caccaataac
    11401 aagagcgatc tgtactcccg acacatgaac ttcggcaatt tcttttgcaa tagcctgaac
    11461 agttggaatg tcaatgccaa ctcctttttc acctgctaat gcttcaccag ataacttaat
    11521 taatatacgt tgatatttag gttccactac tatgttctcc ttagtttgtc cttactattt
    11581 taccacaaac cctcaattat gaatagggaa aggacatttt agaggctaat aaatgtcaat
    11641 taaaatccct tttttaacac caccgatact tcctttatca ttttttgtga gctcatgatg
    11701 tgttaacacc acatctcatt aagagaatca actcctttca tggtattatc gcctacactt
    11761 ttttgtttgc attccatttt aaaccataaa aaagacaaac ctctagtgaa gatttgtctt
    11821 cagaaatttg tctttttgct atgattaggc gatgccctaa tttttttctt aaagtgagtt
    11881 aggatcaacc ttgataccaa caccttgtgt tgatgtgatt gagacgtttg ccatgtaagt
    11941 tcctttagct gttgcaggtt tagctttagc cattacatcg tggaaggctt tgaagttttc
    12001 aaccaatttg tcagcatcaa atgaaacttt accaataaga gcttgtacgt tacctgcttt
    12061 gtcagcacgg taagtgattt taccaccttt agactcttca acggctttag caacatccat
    12121 cgttactgta ccagttttag ggtttggcat caagttacga ggtccaagga cacgtccaag
    12181 acgacctacg atagccatca tgtctggcgt tgcgataaca acgtcaaagt caagccatcc
    12241 accattgatt tttgcaacaa ggtcgtcttc acctacgaag tctgcaccag ctgcttttgc
    12301 ttcttcagct tttgcaccac gtgcaaaaac aagaacacgt tgtgttttac cagttccgtt
    12361 tggcaatacc attgcgccac ggatttgttg gtctgcttta cgaacgtcaa tgttcaagtt
    12421 gtaagcaact tcaacagacg catcaaattt tgcgaagttc gtttctttta ctaatgctac
    12481 agcttcttct acactgtacg cttttgtgct atctactttt tcaagtgcag cacgcatttg
    12541 tttgcttttt ttagccattt taaaattctc cttgtaatgt ggtcatatcg atttgattta
    12601 aaatctccca cgtcactcat ctcttatgat gaagtcgtgc gggtaatagg ggttcttgac
    12661 tgactagtca gtaacagtga atcccataga acgagcagta ccttcgatca tacgcattgc
    12721 agcttcaatg tttgcagcgt tcaaatctgg catcttagtt tcagcaattt cttgtacttg
    12781 tgcacgagta actgtcgcaa ccttagtagt gttaggtgta cctgatcctt tttcaacacc
    12841 tgcagctttt ttcaaaagaa cagcagctgg tggtgtttta gtgatgaaat caaatgattt
    12901 gtcttcataa actgagataa caactgggat gatcatacca gcttgatcag ctgtacgagc
    12961 gttaaattct ttagtgaagc ccatgatgtt gatacctgct tgaccaagag ctggtccaac
    13021 tggtggagct ggtgtagctt taccagcagg gatttgaagt tttacaagtt tttcgacttt
    13081 tttagccatt ttaaaaatcc tcctgttgtg gttttggcgg taattgagat ttttacctcc
    13141 cacagatatg caatattgca taccctacca ttatagctta ttgccaaaat aaatcaagtc
    13201 tttttgttaa aatagtatgt gtctaaattt ctgggaaagt ccaactaacc cttataacct
    13261 aagaaaactc taggttcttt tattccaaaa aagactgaaa caaaggtttt ctctgcttca
    13321 gtcttgacga tattgttgat gacatgatac aatactgttt gactgattaa gcaaagtcct
    13381 tttttgtctt aatcggtggt gtagaagttt gcgcttctgc accttttttc gttttatctt
    13441 actattattg taccacagac aacccagtaa tgcaagggtt tcggggcata aacacaccaa
    13501 aaaagcctct aaaatttaat gttttagcgg ttgctatagg atagattttt tgtagtcatc
    13561 gtctgatcac cactgcatca tgaggataat ggttaaccaa atggccagca cctaagcccc
    13621 tgcctcgata cttctggtac tgctttcgcc agtcgccaaa gaagaggtca cctagtttat
    13681 ttattcgttc caataagata attttagcca tagtacaagc gcctgttact gaccaataca
    13741 tcccacgatg tttcatacgg tacgtcactt tgcgatgctg gctttccatg gcacctatac
    13801 cacgagaggt tagccctcgt aattgtgatg gcctagtatc cctaaaattt ctaaagagtt
    13861 tctgcctaaa agcataatag ttaacagatt cttcctcagt ttctatcagt gtttctactg
    13921 tatcaaagac agtttctaat aatgactttt tatgagtttg aatagcttta aaagctaaat
    13981 cctgtaggac ataaggatag ggcttgaaaa aatctttcaa ctgcttattg agatggtagc
    14041 tgtcccaaaa atgttcatga tacttaatgc caagtgcttt cttaacctct tgaaaaacac
    14101 gtttggtata gcctttaccg ttatctgaat tcgtaatgag gatggtctta tccgttatct
    14161 caaagtgatt gtagagatag tctaatagct cctctcttgc tttatcatag ttagcgttaa
    14221 taatttcatg cttattttgt agaatatagc gatttttacc actctttctt gatcccgtat
    14281 ggattaaaaa atgagccaaa tctgtattat gacgttcatc tcctcctgat gttgttttga
    14341 ccatgacacc atccccttcc aagtagattc tttctgcttg gattttttgt gggtgctcta
    14401 cttgctgtaa gaaacgatag tgttctttct ctattaagag tcgttctgct agtttgacag
    14461 cttttaagac ggcatctttt gtcactgata agccataagc tgtctcaata gtacgacaaa
    14521 cttcccgata agataattta gaagcatgtt cagccatgtg atgaatcaag tcaggagaat
    14581 aacgcatata aggttttaat cccagccatt catcaacagg atagcgtgtg ttttcccctt
    14641 ttcgccaacg acttcttgag aaggtcattt ctccaaaagt gaaaaggact gttcgttctg
    14701 gggcatcaat tctacgataa ccattgacac gcatcattga tgcgacttgc ttgtcataag
    14761 ctgccacttg ctttaaaaag gctagttcac attgtctatt gcgttctgct acgaagatgt
    14821 tttcatcaaa tctcataagt ctattgtatc taaaactaac ctgtttgaaa atccaaactt
    14881 aaacaataga atccttaagc caatctatgg tatactacta gtgttgagag gtcaactttc
    14941 ttattagaca ttagtattta aaatacatct ccctctcaac atcatcgtca cactaagtgt
    15001 gacgattttc gcgttctcgc cataaaagag agcttatgtt ataatgacgt gagctattaa
    15061 ttctttttct cattgcttta acactaatag ctcagctggt cactctcgtt taggggtgac
    15121 tttttgctta gtctctatca atcacatctt gaattttgga gaaagcctta atatcaccgt
    15181 tcaaggctct ttgaagcacc actaaagcta gggccatctc attggttgga tcataaccta
    15241 aaccaacaag cacgtctttc atctgctcat tattgactct ggaagttaaa agggtttcaa
    15301 aggcacgctt taaatccgct cgttggcgtc tgacttggcc tgaagctaaa ccgccttgtc
    15361 gttgaatttt tctttgttcg ctctttgttc gttgattgat tgggattaaa ttctggtcat
    15421 tagccacccc actacctcct agaaaatttg tttaggtttc attcctgttt cacgttcaaa
    15481 gcgttttaaa atgcgttgca cgtatttggg atctagttcc attgaataat tgatacggtt
    15541 tagttgctca cacaccatga gagttgttcc acttcccgca aaagtgtcta aaactacctc
    15601 gccttgccga ctagacgacc tgatcaaccg ttccagtaaa gctactggtt tcatagtggg
    15661 atggtcttga ttggcttgtg gacgcttgat tcttaaaata gatgttgttt ggacctcttg
    15721 gtaggctcta atcagatcaa tcaattcttc cttactctta tcctccaaag aagatgctaa
    15781 gaccgttgat agactaaagt cactgacaaa gtaatgctta gcacctggct tccagccata
    15841 cagacagggt tcatgttgcc aatggtaatc ttgccgccct aacacaaaac tatctttgac
    15901 ccagatgaga cattgttttt caagccaacc tacagctgaa atggcattag aaaaggagag
    15961 tcgttcacta tctgcatgcc aaatgtaaaa agctgcccct gcttttaaat gggaatcaac
    16021 tacttgaaag gaatcagtca aaaaagcttg aaaatccgat gatgccatct ggtcgttttg
    16081 aatggtcaat gcttcactag tttttccttg gtaagccaca ttataaggcg gatctgtcag
    16141 atagaggtct gcttttgttc cttctaacaa cctatttaga tgttccggct tagtagcatc
    16201 gccacacatc aatcgatgcc tacctaattg atacaggctt cctattccta ttttttccat
    16261 gacactatca ggatcctctg taaaatcagg ctccccatct ccctttaaag gagaagctag
    16321 aagattaata gaaaaaccaa actgagccat atcaatagcc atgatactcg tcagttcctg
    16381 tttgagaact tgcatgtcaa aatctgtatt tagagtgatt ttattatgag ccaaaatata
    16441 ggctcttttt tgatcgtcag ataaatgttt caaccgaatg acgggcacct gatcatatcc
    16501 caacgatttt aaagcaagat aacgaccatg tccttcaata atgacattgt tctcatcaat
    16561 agcaatagga tcgttattgc caaaagtttt aatagattct ttgatttgat caatttggta
    16621 tttaggatgt tttttggcat tactctcata tggggtaata tctgacaata ataatgtttc
    16681 aatttgcata atgactcctt ttatcgttga tgaccttttg attgatgatg cttatgatca
    16741 taactttgtt ccatctcatt cgcaaaatca tagtctttta caatacgatc tctggcttct
    16801 tgaagtgcct cacgctctat ttgtaattct ttgatttcct ttcggataag attgcgatcc
    16861 gtatgtttag ccactttagc tttttctaga attgccatcg ttacttcaga tggcaccaag
    16921 ccatcttgat aatctgacaa ggcccctaag actttgttta aataagccac cttactatct
    16981 aactgcgcca atgtttgatc cgttttttct aattgttcta agaagcgttc ttgcatctcc
    17041 tgaaactgtt tagaattagt taccttgtta gccgacaaaa agttaaactc ttcaaccagt
    17101 ctttctaact ctgtcatttc ccaattttta gtgagaatca cttccccact attcaaagac
    17161 aattgtttta ccaaagtgct cccttggatg aagcgattat ctgttgactt gtctggattg
    17221 ataaaataga aatagtcttt tttcttaaag taggctgtga agcttccatc ttcattctgg
    17281 tctaacagtc gagctggaat cgaaactgtt cctttctgtt ctaagccaaa agcaaccgga
    17341 agatggatag actgtgtggt gatctcagaa atttgccaag gctcaattct taccttcatt
    17401 tcaaaatctt ctgccttttt agcttgttcc tcctcatact tttctttgat atggtctacc
    17461 gtgtaaacca cttcattcat cgcaacacac ttttggattt gttcaaagga gtaaatcctt
    17521 ttctttgata aggtgcgatc tcttgtattc ttttcctgca acttgccatc taaaggaacc
    17581 aacaagcgat atttggtaaa cttcccagaa aagtcaatgt gaagatcaag ggctttcgct
    17641 ttctgttgaa aatcctctac tgaaacggag tgctttaaga gaaaatttaa acgctgttta
    17701 atctcgtaac taaaattgtt ttgacgtcgc caagccgaat agtctgtata ggacgttctt
    17761 aattttggtt ttagaatttg agcaccatac aactctgcat gcttatttga aatttgaaat
    17821 aagttgcggg ctgtattttt ttgccaacga aactttttca atgttacctc attggttgta
    17881 ttgaaaataa tgtgattatg taagaacccc ttatccatat gtgtcgctac gacaaattgg
    17941 taatcaccgc cagtaaattc caaggctgtt ttccggccaa tctcgttaac ctcttcaggt
    18001 gttagtttgt catctgggga aaaggattgt acgatgtgat gtgccaagac ccggttatca
    18061 tttttcaaat cggacaaggt agcattatcg tacaattcat cgacagactg tttcaataaa
    18121 atgaaatcat cataaatggc atcacggtct cctgggtcaa tgaggtgatg gcctgaaatc
    18181 aatttcttgt gaacctcacc atctgccgtt agcgtataat caaaagcatc atccttatca
    18241 tgttgctcaa ctttgataag cgtcgcatca tcacgtgtga tataatcaat agcccgtttt
    18301 aagtttttag tctgtttgat ctgaaagact ttggtcacta ccatgttgtt tggcaacctc
    18361 ctttgtttta aattcttgaa caatcatctg ttggagttct ttgacttctt cttgtaaagc
    18421 tgtaaatagc tcctggtcaa attccttaaa ggtgttcacg taacgaacca gctggttgat
    18481 attttgacca atacgattga ccgcaattcg tagttgacgc aattcggaat aatcataggt
    18541 ttcaattttc ccctcaagta acatcttcaa agcgtaagct tgaaaggttt tctttcctga
    18601 caaggtaacc cggcgacgta agtcatctgc ttctttttgt tttgtccgta aaataaattg
    18661 tattgttcgt tttctcttct tttgttccat cttcttttcc tcatttctac ttattcgtcc
    18721 ttactaggga cttgacagtt ttcccagagt ccagtaggct tgttctctgg caagattagc
    18781 atgtggctat ccacatgcgg aaataaaaag ggcgacaagc ctatttgcgg gtatcccaca
    18841 attagacttt tgcctttttc agttttgggg aaatccccaa tccccttttt tgcacgacat
    18901 gcactttgta atgttgcact tttttccgat cctgcatttt gatcaatggc acgactttta
    18961 agagtgtcag ttttgaaaat gcacacagta aaaaacggac aatcgttaca ttgtccgttt
    19021 tttatgttgt gtcaatcgac gtgttttacg gttggctccc aagacaacag gtctaatttc
    19081 attttttgaa attgggcttc agacaatgct tctagggtct taagtgttgt ctggagttcc
    19141 ttctcataat ctgtggcttg gtcagcttga agcattatca aatcgttttt aatgaccgtt
    19201 acgagttcct cttttgtcag ttgtgcctgt tgttgctgga tgactttctt gtctttgagc
    19261 cactcgtcta tctcaaataa gtaggtcatt agaatcatct cagttgtcgt catcatctct
    19321 tcggttatca tatctttgtc ctcctgatag tgtcattgct ttctgtgatg acctacgttg
    19381 cactacggca tcgtaggtcg attgtctttt tttacgcttg cttccttttc gtgagtggtg
    19441 acttgtgttc ttgatgtttt agcggctgct aaactttggt aaaagggatg agactgcttt
    19501 ttcatttctt gtttagtcaa ttgttgggtt tctttattca gtgttactgt ttgatattga
    19561 cttaactgtt gatcaatccg ttccattaag cttttggctt cttcttgaac gatttccaat
    19621 tgtgccgtta agttggcaag cccatctttt tctcttgacc aggacgctaa atagggaaat
    19681 gactcttgac tggtatcaaa tcctagatgg ttcgacacaa cgtaagcaat ggactctgcc
    19741 tgtagttctt tggtacttct tgttagttta ccatcaaagc gttccgtcaa actttgttta
    19801 ttgtgtaatt ccgaatgagc catttcatga atcagcgtcg ataaagttcg ttcatacgac
    19861 atccccttct taataacgat ttcatttgtt tgtggactat agaacccatc ttctcgtcca
    19921 agttctctaa atcgaatggg aaccttattg ttattctgag aaatatctct taagctacga
    19981 tagacatttt ggtagtagtc tttatccaat tgttctggaa tagttcccat agctttagga
    20041 agattgagtt cttttccttc ttggggagag acctgtttaa tgtcaaagac agggacaggt
    20101 ttaaagtaag tgacggtctc cttttctccc gtttcaggat taaggatagg tttcccattc
    20161 tcatcttttt tcataacaga aacaggggct tggatataga tggccttctc acctttttta
    20221 accgaaccat ttcgcttcct ccattcttgg aaagacgcaa ccatcgatgc ttctggaaat
    20281 tgtgacataa tcaattgaat atttcgtggc gagtagttat tgaagtgggc catcccttcc
    20341 aggtattgct tataggtatc actattaaaa tactgtttta tgccgtcttg taagtgttga
    20401 ttcagcgctg cggtattttt ggctttaatc atttctgaca aggtgaagtc acgtttattg
    20461 gcttcttgtt gccttgtcac ctcattatca gaagcattgg ttgggtctgt tccatttgcc
    20521 ttttcaacat tatctggagt cccatcacca tcactatcag aactaaaggg attggtgcct
    20581 agagcgattt cttcatcatc ggttaagcca tcgccgtcag aatccttagg ataggcatta
    20641 tcgtaaggaa cattccgttg cattgtcacc atttgaaggg gttcgaattc gccatttatg
    20701 atcatatctt ttaagacttg tccgccatct tggatatact tatcgttaac ggacaacacc
    20761 gagatgttcc catctttctc actgagtaca cctagaactt cattttcttt cgctttttga
    20821 atcagatcat cagttaggtt cttttttcct cttaagaggg acgaaggaaa ggtgacatca
    20881 tcaatagttt ttaaagcgac gactaaactc ctattattgg attgaatcgc atgactggcc
    20941 tttaagtttc tcattttttg aacttcctct aaatctgtaa agacaaaaga cttggattga
    21001 gatagttctt gaatcattgg caagacttgt atcttgtcat taaaaccatt tgataaggtc
    21061 agattaggat aggaacctcg accttccgca aaatcatcta acagtttttc agctgacaac
    21121 ccttttccaa tcggacgaat accggttaag tgggcaaatt tatctttagc aaaactgacc
    21181 tgaagcgcct tgatttcgtt ctcccctttt aacatatagg tcacttggcg gtctgccagg
    21241 gtatcccgat accagttagc tgtttgttgt aggcttgggg catagtaatt gagattccga
    21301 atatcctcgt cacttgcgat gtggtagccg tctctaacgt ttgacacaaa ggcttcttct
    21361 gtgctaaact gtagtaaagg ataggagaaa gtcgggtggc tggtaacagc ttgctcaaag
    21421 gtatcccttt tggatacagg tttggcactg ccttgagggt cgtcctctaa agagcccgaa
    21481 ctaatttggc tcctatccat tttttcatgc tccagaactt tttctggggc tttttgtgtg
    21541 ccttctgttt gtggcatttt tagtaatcct ttcttttgct tcagataatt attccaatcc
    21601 attttactct ggtgttcttt ccgtggtggg aggtctacgg taattggaat gccatcttcc
    21661 tgtaactcct taataaagtt tcggcctgcc tcgtcattat caacggtaat tgtaatcaga
    21721 ttgggattgt ttttaaggat tctggtcgtt tggttaatgg catctatcgc tcctctaatc
    21781 gactctctgg gcatggtttg agaatactga ccatctgtca ataaatcagc cgtatagcga
    21841 ctaatcaccc cttttttaac cccatccata gccactaagc ggacattctg taaactctcc
    21901 ttatgtagtt cataataaga gagaaggtca ataggagctt ccgaaaacac gagacgttta
    21961 ggttttccaa tgtccaaatg aaaacctgct agaccgtctg aatgcttcat gatttgttta
    22021 agacggccac gttcaggatg ctggacttta ttttcaacga tcccctgaag gctaccgccg
    22081 atcattcggc cgtcttccgc aaaactttta aagataataa caggttcaaa ataatcaccc
    22141 tttttcaacg tcgcagagct catactacct gatgccaaag caaaatcaat ggtctcatca
    22201 gatagccctc gttcttcttt aagatactgt cgccctaagt caaaatcgtg atgttcataa
    22261 ggagcgaggt agtgcttaaa gggttctcta acgactggtg ttaccgtaac cgattcaaat
    22321 tgccctgttt ctaaaaagct gacagtttct cgaaagctag gtttctttcc tgttagctct
    22381 tcttggatga cttggactaa atcaatggta ttggtgccca tgcttcttga ccaccaacga
    22441 aaggtgttag tttgggggta aatatgaaaa ctatcatgtt catcccaata gagatgccca
    22501 cctgaacctt gtttcaagtt aagtcctagt gagctcgcaa cggccacaat atctatagcg
    22561 atgagtttct gacgttgcgc ttcaaaacgc tgagataata aatctcttgt atttgtcata
    22621 tcagacctcc cccttaaggg cttgcttaat aaaggttttt gcttgtttga taaagccatc
    22681 tacctcatct tgcgtgtaaa caccattgtc aaaggcatct gttatctcca gagtttcttc
    22741 atggtcaaaa aagagatcat aatgggtgag attgattttc ccattggaga agatacggat
    22801 gagtacctta ctatagccaa ttcgtaactg aattttagta ccccaatggt tatagcgttg
    22861 aattgacatt gtggttttag atgaattcac ggctttgggc tttagggttt gacggtgggc
    22921 aaagggttct attgtttcaa taaactgttt tttaacgtct aatcgacgta aagtttgagg
    22981 tgtcatatct taatcctttc tattaatacg aaatgagtga catcatacta gatttccact
    23041 cgttggtcat caaaagaaac ctctccgaaa ccttcacggt cttcaggggg aagttcaaaa
    23101 atttctccag tatccatatc cactagtttc gtagaggttt ttggtgtctg agagaggctt
    23161 tctgaaggca tttcaggatt agttataggg acttggtcac gagctgacgt ctcaggagct
    23221 gattgacgtg tgttgtcaaa gccgttttct actaagaagg cttggtagcc agacatatca
    23281 ggagcccaaa catggtcttc tggaatttgt ccagtcatga ctgcatcaat aaattccgca
    23341 ccttcttcca taaagcgttt atagtgatac caggtcttat cttgataatg attagcgagc
    23401 ctatccttca taggatgatt tgataccatg gctttcttat ctcgaaagac attttgcttg
    23461 gagataaaaa ctaaggcctc atcgacacca atacgagcta tttcatctgg ggtcatgaga
    23521 tcccgttgat gcgcttgtct actggttgtc cctgttcttc gctgtccccg ttgttccgaa
    23581 taactggtct gggtaatggt ttgtttacct gcccgcatcg aaaaatactt catggtatct
    23641 tcatcattgg ttcctaaaaa taaaagcgtt gcacagttat taatcatcga ttttctagca
    23701 ggcacaccat ataggctgtc tagttgacta atggcttgaa tgatgatttt tatagacatc
    23761 tcacggctac gaatagaggc taggacttcg ttaaagtgtg gaatcttacc acaattggca
    23821 aattcatcga agtagaattg cacgtgtaat aaatctttca gttcatagcc tttcttctga
    23881 ccttggataa tagcatctgc actatgagtc aattggtcaa aaacaaccgt aaagaatgtg
    23941 gaagccaaga agctataagc cttattagtt tctgagatgg ccacaaagac cgctgtcttt
    24001 tcagtattcc aggtatccat ttccatggtg tcagtcttaa tgagattcgt taccgcatca
    24061 tgatcaaaaa tggagtactg agtggccaca atagctaaga cactagtcct ggtttctgcc
    24121 tcaaagttac tgttaaagag ttcccactgt cgacaggcat agttacctgg taatttttct
    24181 tccaattgct taaacatctt ctcaactgca ctgagttcct tttcattggg gcgtttcaaa
    24241 tttctaagta aatctgccac cattgataag ttcggttcat aatgtctcac ctgactatca
    24301 aaataaagat agccaagtaa agcacggttc aaaagaagct tggcctgatt ccagaagtcc
    24361 tctccttctc gatctccctt ttttgtccct tcgacaatgg cttctgtaat gcgatcaata
    24421 tccaattctg atctcatata cctaaagggg ttaaacatat ccgaattggt taagttaacc
    24481 agatcaaaga ttttgatttg atagccattt tcttttaaca gcgttcctac ttctcggaca
    24541 agcaaccctt tagggtccgt tacgataaaa gaggaattca tttgcatgag gtttggcttt
    24601 acataggtgt aggtttttcc atctccaggc agaccagcta ctaagacatt tttattgagt
    24661 tgtcgctcaa acggcaagcg cttattgaag agtcccattt gagcttctct cgagaaaatc
    24721 atattatttc ttggttcttc atcttgaaat cctttgagtt cttgagccgt cgcaaagcaa
    24781 gcagaccctg attcttctcc atgccgataa ttaccatcta atctaatctt tagatagaaa
    24841 agtaagccaa caaaaaagcc cactagagca gaaagaagtg ctagtgggct agtattccaa
    24901 tagaagtaag gtggttccgt tatcttttca aaaacatagg tatagggagc aaaaagattg
    24961 gtcatatctg cctgtggtgc catacagtaa aggacataag cacgatgtgt caggtaggct
    25021 agaagcaaac tgagcagaag atagggaagc aatcgtttac gttttagttc catcagatgc
    25081 cctttccttt cttcttggtt tttactgctt ccgttgattt cttagaggtt ttcttgagtt
    25141 tttcaatctg ttgtttaggg gttaattcat caggcttctt catgtattta tctagtgctt
    25201 cttttggatt agacacaatt tcctgattga tttttctgag agcttcttga atgacctgtt
    25261 gattaatagc ttcaaaccag acttgcttgg tgccatctcc attcttttta aagtgaaagt
    25321 taacccctga ctttttgagt tcttttctta atttttcaag attaacctca gcctcttcaa
    25381 agtcgatatg atcttttgtt cggggtaact gattgaaatc cttccaggac atctcccctg
    25441 attgtttgtg ctctttataa gtcttagctc cttggctaac agcataagcc aaaaactgaa
    25501 gtaaatgttt tcctgtctcc aaggtaaccc gtgagccttt ttccataact cgttcttgat
    25561 ccatttgttt cgtctccttt cttcattagg ggtaagcggt tagtcttggc tttttgataa
    25621 caagatagcc atactgagcc ttcttatcag ccctaacagc tagtgttagg cgcttacttg
    25681 atacatgatc ttgtgcctct ttgatattaa cgacataagt aacaagagtt gtattccctt
    25741 ttatttcctg attttctagc aaaacactaa ctggtgttgc tttgtttatt ttaagatctt
    25801 ctttggacag cttctctgat aagtaatcct ctagattaag actttgagag aagtaactgc
    25861 taatgaaata gcgacaaaag acatctgcct tttgattgat cactaccgtc tctactttgg
    25921 gagtcacctg cggttgtgtc ttaactaact gcaaggtctc caaggacaag tagatactca
    25981 ctaccgatag taccatcggc agcaaccaca tcagcccttt tactaacttg gagacgcccg
    26041 ttttagattg ggagtcattg gaatttgaac tattaatagc ttgtggttgt tgttttgatt
    26101 cggaacgttt ccagaatggc ttcttagcgt ccccctttcg tccaaattct ccgattaatt
    26161 cctgaacctc tttgtcttct tgagctggga tggttagttc cattgattcc aggacttctt
    26221 catttttatc caaatgaaac agataaaatg tagctctcat gtttaactgt aggcaccgtt
    26281 tttcctctcc ttctagtgca tatagaagag ctgccaggtt ttgaaattcc tgttccttcc
    26341 catcagattg attctgaatc cgaaacatta cccctcacct ccacgttctt ctttgtaagt
    26401 ggctaaaata gcttctaagc cgtgtaaatc aataccatat tcggccatga tttcttgttg
    26461 ccgtttgcct tctaagatgg taatatcatc ttttagcgtt ttgattttct tttgaagagc
    26521 gtcttgactt tcttgagctt tttctagctg ttttatctta tcatctaaac gttcctgagt
    26581 ggatttctga cgacggcttt ttgatgaact ggtttgatta atatattctt catttgtcat
    26641 gtttttatct cctttacttt atttagtctg tttctgaagg cgtaattgct ccataagctg
    26701 cttcgctttc tgttaagtca gatgaatctg ttaatagtaa ggtactcatg tgattcacta
    26761 aaaagttacc attaactttt gcataatcta attgaatggt tgtatgattg acaactcctt
    26821 tttgtgcccc ttctgcatta ttcttttcct ttaagagatc atttgtataa gtgaccttgc
    26881 aaatgacttg atgattgatg tgatcaatat agatttgtgc tgattcaaag gcataattaa
    26941 taatataacc tttatacgtt tgactctgag ccttattttc ttctgagact gtcgcattat
    27001 aaagcccttc ggtcatatat tctttatacc gctgacgatt ttcttctaaa tctttcttcg
    27061 tataataagc aattagaaac ttcttgacta atgattcatt cagtcgctta tcatcagact
    27121 tatttatcgt tgatactttt gtttctgaac tatcttgact atttttaccc atctggccaa
    27181 atccaaatcc tatacagaat attagaataa gacaaacgat tccaatcgct cgtttaaaat
    27241 aggttacttt tactgtatca atcatgatta cttctccttc ttgttttatt atttaggtgt
    27301 cgcaaagcta taaaaaggag ctgggcgaca gactcggtag tgaattttat gttgaatccc
    27361 cccataattg agttcagaca ctaaaaatga gccatctggg ttaaccactt ctacaatccc
    27421 aacatgaccc cattgtggaa atgtgccatc aaaaccgccc gccgttgaaa caacagctcc
    27481 cttgatagga gttggactat atcgccagcc tttagcaacc aaagatgcca cccaattttg
    27541 gccattacct aaatagccat aagaacctga taaatcggta atactaccta gctccactag
    27601 acgattgtag ctataccaag tacactgtcc tacaggataa ccattaccag cctgtgtcgt
    27661 catcgctctt tgggttggtg ggttaggaaa cctagagcga tactcttctg ggaagttata
    27721 cgatgaagca agcgtacctc cacctacaat attagggtat ttaaaccaag aaagtgcttg
    27781 cttggcaata gcttgtctct gagctaattt attaccaggt acaccttccc atttggctaa
    27841 gaactccgct gttaaactat tcagatcact atgcccagtc gcaatctgtt taaagatgtt
    27901 aatgtagtaa ggattatccc cttccaacat aaattgaact tgtaactcta gactatacca
    27961 ctttttacct ttacgtttag cataggctcg taataacgta ttacgattcg caccgtcaga
    28021 ggtatctgtc cattgtccta aaccgagtcc tcgatgaagg atattcggat agccaccgcc
    28081 ataaatggcc gggccaccta acgttaacca ggactcgtca tcccaagaag agtcagaagc
    28141 gcctactggc gggctgaggt agtccccttc agctcgctta gggttaatac cagactctac
    28201 tccaaagcaa cctacaatag ctgcaatccc attatcggtt gcctggggca aatatttttt
    28261 aaccaaatca tagaattgct tggctcgacc actcatttca gatggggttt gagtcacaat
    28321 agttgtttct gcatacttca caaagggaaa ataaaagcct gggttggtga gtacccaaac
    28381 ttctttctta tccttctttg tttgtatcat atagccgtaa gaaacctctc tatccctaat
    28441 attttttaac catgcggcat ctttatcatc tacttccccg tagcgcttag catacgctat
    28501 tttttgtgta cttcctgata ttgtagctaa ttcttgacct gtttcaacct tatctcctgt
    28561 tttgactcga ctatttgaga catcataata gataaagcgg gcctccttat cttcaataat
    28621 gaggttagtg gttttcgttt tttcaccctt taagtctttt gtggtaacag ctattttacc
    28681 atccataacc gcatacaact tttgactggc ttttgcttga agtgtcgtcg ttggatcaat
    28741 ggtagcttta tcggtatagc catagcgttt tgtcacagtc aagtattctg aatctgcttt
    28801 gtcatcatta gatgaataga aggggttaga aagttcttga taagctaaga atttgcccgt
    28861 ttcggcttga ctatctagaa tctccttata ttcctcaaga tcatcttttg agaacttgat
    28921 ccactctttc ccattggtat agagttcagc catggttttt aggtgatcaa tatcttggtt
    28981 ttcttccttc caaatatcat ctagggcatc tgagaagtga ttgaaaccta aggcacctgt
    29041 gactttccca ccaaagccat cgtcccactt agcatctggt tcccactctc caccatagcg
    29101 gtaattcata tagagtaaga tggaatcaat atcggtatag taatccacct tatcagaaga
    29161 cttctgacgg tctacctttg aaatatgaag ccaggattga ttgagagtaa attcattttg
    29221 ttggaccaca ttactcgaaa agaccgaaga taccaggata acgattaaca aaagcaagct
    29281 gatgactcca gtcacaaccc aggttatcgg attagcaata atgggcgtaa tggcgctcac
    29341 taatgctttt gaagtagcca caagagtttg agcggtttta gaagccactt taaccgtttc
    29401 ttgagtagct tttacgcttc cttttcgtgt ttgatgatag gcgtacttag ttcctttagc
    29461 tcctagtttt accgttccct tggcaccacg ataggtcaat ttgatacctt taccggttgc
    29521 acgtcctgct tgtttagcca tcgcttgggt ttgacgaatc tgatgcttag ctctcaccaa
    29581 atcagataaa gtatcatctt gttcgaaccc catttctagg atttcttgac cttttcgttt
    29641 agtgatacgc ctacctgtct gtctggcttt ttgactaaga gttggattgg ttttgcgtac
    29701 tttctttttg acttttttag catccttgta cttagcttta gcttgtttta gcttctcctg
    29761 agctttttta agcgcttcgt cgtctattat tccagcccta aagtctgttt gtgctttttg
    29821 ataggcttct ctagcttctt ttaactcttt agtggctact tgaagctctc ctttcgctgc
    29881 tttttgagcc tttctagcgg aagcctggtt atgcctgtgg acacttgctt taatctgacg
    29941 ttttcttaca actcgacttc taaggtcttg tttttcttct gtcacggttg cctcctttca
    30001 tatttattaa tgtcctaatt attcttactc catttttcga taagcatctg ttgcgactaa
    30061 gcggaataat tctgtatcct caggaatagg attttcaaat gggacagttg ttgtacctgc
    30121 aataattaag cccgttccaa tcgcttttgg cttttcaata tagcgaacga gagcatcggt
    30181 tagattaatg gtttttagta agtagggaat ggtcgttttc ttttgtttta agagcacgag
    30241 gaactcacta ttatatagta agttgcgacc ttctttccga gaaagcaacg tttccacatt
    30301 ctgcgtaatc cctgttggaa ttgacccgta tttacggata cgtgcataca ttttagaaaa
    30361 gaaagccgcc tggtcatctg tttcaaattg attctgcatc tcatcaaagt aaactctagt
    30421 cacaaactca tctttgtgat caacgacgtg ttgccaaata taatcctgaa tgaccatcat
    30481 ggcaaagggt tttaatttcc cagatagttt tttcaagtta aagataacaa cttggttatt
    30541 gagatctaca ttcgtttcat aagcaaaaat atcttgagat cctttggtat aggattctga
    30601 ttttagagcg agactttgcg cttcctcttc aggctgttcc aagagaatat catgccaatc
    30661 ctttagggtt ggggtgcgat cggtaatctg ttcataacaa aggcgagtga cacggtcaat
    30721 aagtgacaca tcatcgtcag tcacttcttg aaggatattt tcaaagagtc ccatgataag
    30781 agatgctttt tgccctacaa aatctttatc ttcatctcga agcttatcca gatcaggaat
    30841 atccatgaga ttaaaatgag ttttcgttcc tggatagata tcaataacct gagcaccaaa
    30901 ggcatggcca atgtccacgt actcttcctc gggatcgact atgatgaccc gatcgtttgg
    30961 aaagcgtaaa atagctggaa tgacttcgtt tattttaaca aaaacagact tccctgaccc
    31021 agaagaccca agaataacac ctgaagacgt atataaatcc cgttgtcggt caagagaaat
    31081 aatattatta gaaatttgat tttgaccata gtaattagct agtggacttt gagattgtaa
    31141 gtctgtatta gtgaatggaa tttgggtagc tatattggtt gtggtcatat ctcgcataaa
    31201 gcgacgtttc acatcgatat aagtctttcc aatcggtagc atactattga gcgcttcctc
    31261 ttggtgataa taagtttcct caaattctat cacgtgtttg cgtccagcct gtttgatgcg
    31321 acttgtgtag tctgccaatt cttcagcact atcagctttt accataatca aaaaaacgcc
    31381 agaaaacatt ttctgatcgt tgtcattgat ttctgctttc catttttcag cttcatctgc
    31441 cgtatcttga gcaacactag aaactgctaa gttacttgaa atcccttttt gagcggcaga
    31501 cacttgcgat ttaaccatat ccattttaac accagcttca gctatattga cttttttcac
    31561 cgcttcagca acgtcataag gctgggcatg aatggaaata gctaattcaa tcccaatgtc
    31621 tgttaaggat ttaatgagtc ggtcattaag gaaggctggg aaagttctgg caaagagaat
    31681 cttacaatat ttcttatcca tcataaactg atcaggttta aaccaaagac gaccaggagc
    31741 gatgaaggat ttagtgctca gacctgaaat tctcacatcc ttatagtcca catcgagata
    31801 aggattccct ctcagtaaat ccgcaaagat attgagcctt tctgtcccat ctaacgactt
    31861 gagaaggaca tcaactaatt gaaactgtgt tgtaaaatga gtatcaacat catttaactt
    31921 acggtaagct tgtttccgat ctttagccct tgtcgagacc gtcacaaatt tttccacttt
    31981 aaagttattt tgatcttttg caaagcgaga acggataata ttattgtatt ctttccgaaa
    32041 gatatctcgt tcatcacctt ctaagtcata ggtaatctga tccagtaagg ttgtagggac
    32101 aggacgatta agaatcgtca actgataggt attttcacta tctagaccat ttaaagcatc
    32161 aacatagtat tcaataatat ctagtttttc gtcttcacta cctgtgatgt aattagtatc
    32221 gcctaattgc caagacttgg aataggtttc atcaacaatg tgcatgagtc catcttcaaa
    32281 gagagaggtg tactgaattg tattttgtgt actagccttc agagctctct gtaattgttt
    32341 tgctcgttct ttttcagttt tcgttagggt cattccattc ttggacaccc ttttggggaa
    32401 taaacgcacc atgaatttcc tcactttcat attcggtttg gtaggccctt tcttgcacct
    32461 tgagcctaaa ggtaatcact tctttgatgt gttcatcttt tttgatgcca tagataaaag
    32521 ccggtggtac ggttaaaact agcgaaaggt aaaagagaat gattggcagc tgcaacaatg
    32581 agataactgt cgcaaatcca acccccaaga caattcctaa taccatcacg acttggcgcc
    32641 aggttgcgcc accaataacc cctcgttcaa attgatctat agctttaaaa aattcagatc
    32701 ctaatttgtt catctggtct cctttcttgc atgaaaaaaa cagtttaaag aaactgcttt
    32761 ttacttattg tacttttctc tctccttagt aagaatctct aagggaattg tagtcatttg
    32821 aatacggtgg tctcgtcgct caaaaccaaa cttttgatag acataatctc gtcgagcatg
    32881 attttcggga tctcgctcat caacatgtga taacttgcct attatcctca ccttttctcc
    32941 aaataattga ctaatatgga ataaggcctc tcgtaacaga aaactgccat aacctttatt
    33001 agggggcacc ataagaaaat ctctaatcaa taaatagttt agcgtcccag acttatccct
    33061 gtctttatca tggtaataag cttccacgtt taaaaaattc aatcggtctt tacgacgatg
    33121 tttaaacgta tcatttactt taaactccag acgattaatc cgttttagat gatcaagcga
    33181 ataagacaca ctcgcaagca tatagatgcc tttgacagtt tgacaataga gtagctgtcg
    33241 attattctga ttgaactctt caaagtaggc taattgcttt ttcaaagctt tattttctct
    33301 ttttagagtt cttaactgcc tatcataagt tgaaatcatt gaataagctt cgattagctt
    33361 ctgtttggtc ttgaaaatag cgctcaaagt ctttctctcc tttaaaagct attctaccac
    33421 gttctaaaaa acttagccac ttctccagcc actgtgaata ctgtttttgg gacagtttcc
    33481 caattgcaaa gaaatagttc aaatcatctt gaagtatttt taagatggtg atacctgctt
    33541 ggcaatctcc cgtagcttcc acaaaccgcc aagcataggt gtaaaaaaga tcatcgcctt
    33601 gtattaagcg aatagcttgt ggcaattcac ttactgttaa ctgcccttgt aagagacaat
    33661 cagctataac atctcttaga agccgatgtt cgtattcata agaagataat cgactcactt
    33721 cactttctaa atgactaatt ttatctttga aatattggta ttcttgacct tgattaatca
    33781 tttctatcgc ttttcctttc tagcataaaa aacagctctt attatgatcc gcttctactg
    33841 atttgttagt ttgattatct gatgattgag tagatggccc ataaaaagag tcaacaattc
    33901 cagcagtgcg catagctgat tgcatagcag agcgagcgag ttctgaagca gcgatacttc
    33961 tgactttcag ctcccacagc tcatcttctt tttccttgat gagaccgtcc atccattcat
    34021 tatctcggat aagttcgtct cgtctttgtt ttagtttttc taaattcatt aggctatcct
    34081 ttcatatatt atagagattg gtctatcacg acacctgtaa taactgctta gctttgcgct
    34141 gagaaccaaa caacaatatc aaaaagacaa tacacttgcc tatgtaacta aatcctgctg
    34201 caaaagcacc tacccatgaa tctttagata ttttaattac agcatctata ttgagtcctt
    34261 gccatatagc tagtaataaa acaattactg cactttgaag agcaatcgcc ccaaaagttt
    34321 tgaggaaatt tttggcaata tacctagtat catctcccat ccaaaaagca acgataactg
    34381 gagcaattgc tttatagaaa tatagttcaa taaaacgaag taataccata acttttatag
    34441 agatcattgc tccaacacca gctatagcag ctagtccatt tactagaata cggacaccta
    34501 gattcccttt ttttaaccat acaaactcaa acatgttgtc accactcaag tctactccaa
    34561 tcagtttggt cacaccgttc gtaaaccata aaatggcatt gagaatcgcc cctgattgag
    34621 aaactaggaa ataagcaatg aaatatttaa cagccacttc taagaatagt ttccacgtca
    34681 tctctcctcc ttggttacga ataaagcgat accaagataa cagctcaagc aaaaataaaa
    34741 tggataccaa aatgtatcca atggccatga gggatttatt aacggcagtc atggatctat
    34801 tgacggagga attatagctc cctagttcct tggttagttc tgaaagtata tctttcatcg
    34861 ttctcctttc ttgaaaaaaa taaaagaacc tcgaaaggtt cttgagtatt aagcttctga
    34921 ttttgaaaaa gtcatgacta aagctaagaa aacgatggta atgccaataa tccaggcatc
    34981 agcgacagga tgtgggaaga aattgggaac agcatcctca aagaagttaa caccaaaact
    35041 gaaatcaact atatctttga ttggactagg aaatggattt ttatataagt caaaaccata
    35101 aattaatcca gcaataatac cgaccaacca tcctaataca aattttgata taaaccaaat
    35161 aacaaaaaca ccaatcgttg atttaatcag attaaagaag aagagagtca aatagactgg
    35221 tgtttgaata agaatgagga gagctctaaa gaaatttcgt atcacaaagc tgagccctgt
    35281 ttttaagcgt tcccataagc ttggtttgta ggaagcattg atacgctcaa tctcagcttg
    35341 tgtttcttca ggtgtatgaa acgtgacaat cccttcccaa ggatcaatcc cttgttcaag
    35401 ttcttcagct gttggtggac gaccgtgacg tttctcaaag tctctggcaa atgccacata
    35461 atcaaagctt tcagccatct tcttcccttt ctctcgtttt actttattat ctttattata
    35521 ccatatttta ggttaatgga tgacccattt tcgtttcttt agccacattt tctaaactag
    35581 ttttaaaatg aaatagctcg catagcagct acaatcgcag ctgccacacc agccgcaatt
    35641 accgccaagg cacctcctga aatcatagaa gtaaacccct gatccatcat ctgaggactt
    35701 ccatttttac gccctgcaaa ataatcaaaa gcgcctgtca ggacccatcc gagtccgaca
    35761 atcgcaagta ttgcacccat agcggtgaca acacgtacag ctgtttccat atgttgatac
    35821 cttctttctt caaaaaaaat caagactaga gggttctagc cttgatcaaa cgaggaaacc
    35881 ttctgtctta tcttttttag gtttcctctc tgcctagttt tttgactttt cggtcactac
    35941 tctagtgata aaccaaggtc tatccactca ccctaacaag taaccaatag taaacttttt
    36001 cggctagttt tttgaaggga aaggagatcc ccctaatagt tacttgctag agagaatgga
    36061 tagacccaaa gtaatctact ttgatggctt atccattaac ttggttacta ttgacgcttt
    36121 ttaagcccta cataacctaa gagtgagagt aaggctgccc caagcactgt taggacagat
    36181 accccttgct cacctgtaga tggtaaagct ggtgctttag gagttacagg ttgaggttgt
    36241 tctggcgtat gagtggtgac tttattagac ttcacaggat taccgttgac atacaaggta
    36301 tactcatttg ccacatcacc tgctttgatg cgtttaacaa ccacaaaagc atctgcacca
    36361 aattcgctag aacgaacgac cttagctaag aagtcttgct tgaacgctaa ttcatagtga
    36421 cctgtttcct tattgtaaac tgtctcagta tatttcgcta agtcagtacc tttagtgata
    36481 acactaccat ctgataaagt catatcaact gtcgcaagga ccttgtcttt ctggtagagg
    36541 tcatgagtat gctgaagctg gtccacaaat ttatattctg tcaggtcata gccacggtta
    36601 gtcggaacaa cccaaccttc caagcgatag gtgacctcat caccaacttt aacagtgcca
    36661 gcattgattg attgaccacc ttctttatcc aaaacatcct tatgaacagt tagttcagac
    36721 aggtggttta ccacgatatt accgtagtat ccgtttccaa aatcaatttg gtaggtttgg
    36781 ttagtaatgt cacctttctt gaattcctgt ttaagtttaa aggacaagtt gtaggtaata
    36841 tctagtcctt tttgaacata agctttgtaa aaggctgctg ggtctttagc tacccacatg
    36901 tagaattcac cgactggaga aatgcctgat gccttgatca gtgcttttag cttatcgtca
    36961 agcgtatctt gagataacac atgacgcatc tctaagagat tggttacatc atctccatta
    37021 gcggccttaa tggaattcac aacgagtgaa tgaccatcga tagcttcatc cttgtaatca
    37081 tcgacataga taaagccttt catgacactt tctttggcag ctgtcatccc tttgtactga
    37141 tcaaaatctt gcttagccac gtaagtcagc gtgctgtttg gcaagacaga cttcccatca
    37201 atggactgac ccttgtcgtc cacaatggtt ttagttggct gaatcagatt atcatgcggt
    37261 gttggattat ctcctcctgg gttacgaggt gttttcggat cgttccctgg tgtataaatc
    37321 actggtgtgt tagagattac cgtgtagcta ccagttggag tagtgaccac cgtcttaaag
    37381 gtattgtgat aagtccccgc atcattcagt aaacgaccaa ccagtgatac cttagggact
    37441 tctacatctt ggtcacgttt agcattgaag tgagccaaaa gggattgaga agccttaaga
    37501 ctaaccttgc ctgcttcatc cgttgttatc acccattcag gagaaagggc ttgtgtggcg
    37561 gtaacatcta actcaaaacc atctggtagt ggatcagtta gttcatagct tgtgatgtcc
    37621 tgacgaccag ctttgagaga agtattaaca agctcccacg ttaccgttga tccttttggt
    37681 accagttgtc catcgatatt aacctgatca ctattagtaa cagacttaac atttgttggt
    37741 gtttgtttca cttgaacagg atgaaccata acctcataga cgaccttttc aggaacggtg
    37801 acatggggtt tcacaactga tttaatcgga ttataaatct ctggcgtaaa gctcttgaga
    37861 tctggcttaa ttgcttcagg ttcaactggt gttggtggta ctggtttttc cttctctaag
    37921 tttggaacat catctgttgg cttttgagga gcctctggta ctggtttttc tggttctaaa
    37981 acaggtttaa ctgcctctgg tttaactggg gttggaggaa ccggcttttc tttctctaag
    38041 tttggaacac catctgttgg cttttgagga gcctctggta ctggtttttc ttgctcaact
    38101 tttggtgtaa ccatatcagg ctccactggc ttttctggta cttcaatatg tggcacagca
    38161 tcattgttgt tagtataaga aactaaagca gaaccatgtg tgtcgtgtac ccagtcatca
    38221 tgca
//
LOCUS       DATWVB010000016        31829 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.016, whole genome shotgun sequence.
ACCESSION   DATWVB010000016 DATWVB010000000
VERSION     DATWVB010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31829
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.016"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            47..119
                     /locus_tag="VCX65_000903"
     tRNA            47..119
                     /locus_tag="VCX65_000903"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:80..82,aa:Phe,seq:gaa)
     gene            139..219
                     /locus_tag="VCX65_000904"
     tRNA            139..219
                     /locus_tag="VCX65_000904"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:173..175,aa:Tyr,seq:gta)
     gene            226..296
                     /locus_tag="VCX65_000905"
     tRNA            226..296
                     /locus_tag="VCX65_000905"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:258..260,aa:Trp,seq:cca)
     gene            308..380
                     /locus_tag="VCX65_000906"
     tRNA            308..380
                     /locus_tag="VCX65_000906"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:341..343,aa:His,seq:gtg)
     gene            389..460
                     /locus_tag="VCX65_000907"
     tRNA            389..460
                     /locus_tag="VCX65_000907"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Gln,seq:ttg)
     gene            480..563
                     /locus_tag="VCX65_000908"
     tRNA            480..563
                     /locus_tag="VCX65_000908"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:514..516,aa:Leu,seq:caa)
     gene            823..1008
                     /locus_tag="VCX65_000909"
     CDS             823..1008
                     /locus_tag="VCX65_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053376.1"
                     /translation="MSFEIFTLIIGWKLVGYRVMECGSSFKQGDYRLVVHICLLNVRD
                     EMLSQQGHEDKADWPEP"
     gene            1646..1954
                     /locus_tag="VCX65_000910"
     CDS             1646..1954
                     /locus_tag="VCX65_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEP5053377.1"
                     /translation="MKHRFQVKRGVSVYLEKRIPMCAGMGGGSSDAVTIRALNQLWLL
                     TLSRKDMMDIGIPIGSDVPYCLLSGRAQVTGKGEVVCRILGLLSSWVVLVKPDFGIST
                     "
     gene            2009..2221
                     /locus_tag="VCX65_000911"
     CDS             2009..2221
                     /locus_tag="VCX65_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEP5053378.1"
                     /translation="MVAAIEAGNYNDGILTEMNNLLEDIFIAKRPFIQKIKEKTLQAG
                     AATTLMTGSGPTVFALCQTEKQTIIV"
     gene            2331..2774
                     /locus_tag="VCX65_000912"
     CDS             2331..2774
                     /locus_tag="VCX65_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEP5053379.1"
                     /translation="MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2778..3497
                     /locus_tag="VCX65_000913"
     CDS             2778..3497
                     /locus_tag="VCX65_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEP5053380.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEVETDDEKGGHGHA"
     gene            3490..4305
                     /locus_tag="VCX65_000914"
     CDS             3490..4305
                     /locus_tag="VCX65_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEP5053381.1"
                     /translation="MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVLGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4345..4728)
                     /locus_tag="VCX65_000915"
     CDS             complement(4345..4728)
                     /locus_tag="VCX65_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEP5053382.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMDEGTHFHLHLIPRL
                     TNDSFWESITINQENWDLTPFLKHL"
     gene            complement(4779..6035)
                     /locus_tag="VCX65_000916"
     CDS             complement(4779..6035)
                     /locus_tag="VCX65_000916"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEP5053383.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLFLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            6127..8439
                     /locus_tag="VCX65_000917"
     CDS             6127..8439
                     /locus_tag="VCX65_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP5053384.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQEHKGVVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLYNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTIRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADSNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8703..12269
                     /gene="rpoB"
                     /locus_tag="VCX65_000918"
     CDS             8703..12269
                     /gene="rpoB"
                     /locus_tag="VCX65_000918"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEP5053385.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12360..16001
                     /gene="rpoC"
                     /locus_tag="VCX65_000919"
     CDS             12360..16001
                     /gene="rpoC"
                     /locus_tag="VCX65_000919"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020904830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEP5053386.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDRLDINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAVFTAEAE"
     gene            16153..16518
                     /locus_tag="VCX65_000920"
     CDS             16153..16518
                     /locus_tag="VCX65_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEP5053387.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            16611..17549
                     /gene="tadA"
                     /locus_tag="VCX65_000921"
     CDS             16611..17549
                     /gene="tadA"
                     /locus_tag="VCX65_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEP5053388.1"
                     /translation="MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYVRLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            17533..18519
                     /locus_tag="VCX65_000922"
     CDS             17533..18519
                     /locus_tag="VCX65_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEP5053389.1"
                     /translation="MKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRSQLLQLDYV
                     LKMEESLLKGQDLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRR
                     KTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILL
                     FGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDI
                     MAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELE
                     IYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF"
     gene            18521..18847
                     /locus_tag="VCX65_000923"
     CDS             18521..18847
                     /locus_tag="VCX65_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEP5053390.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18822..19250
                     /locus_tag="VCX65_000924"
     CDS             18822..19250
                     /locus_tag="VCX65_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEP5053391.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19255..19491
                     /locus_tag="VCX65_000925"
     CDS             19255..19491
                     /locus_tag="VCX65_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEP5053392.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEITLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            19484..19918
                     /locus_tag="VCX65_000926"
     CDS             19484..19918
                     /locus_tag="VCX65_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEP5053393.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD"
     gene            19902..20228
                     /locus_tag="VCX65_000927"
     CDS             19902..20228
                     /locus_tag="VCX65_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEP5053394.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVFFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20326..21279
                     /locus_tag="VCX65_000928"
     CDS             20326..21279
                     /locus_tag="VCX65_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP5053395.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN"
     gene            21338..22534
                     /locus_tag="VCX65_000929"
     CDS             21338..22534
                     /locus_tag="VCX65_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEP5053396.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGEISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22721..23029
                     /locus_tag="VCX65_000930"
     CDS             22721..23029
                     /locus_tag="VCX65_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053397.1"
                     /translation="MYVFIEPNDLKDYLITVYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLTIRDLVSYKLALIFAYLYLIIRSLVAKKMEALGKITTNSQKPPFDTSQVLC
                     "
     gene            complement(23112..23882)
                     /locus_tag="VCX65_000931"
     CDS             complement(23112..23882)
                     /locus_tag="VCX65_000931"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEP5053398.1"
                     /translation="MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLT
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRNLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTTTVSSAIDKTIDKAKSL"
     gene            complement(23930..24997)
                     /gene="pepA"
                     /locus_tag="VCX65_000932"
     CDS             complement(23930..24997)
                     /gene="pepA"
                     /locus_tag="VCX65_000932"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEP5053399.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPNIENIVFDGGFTDKAEAESFGITPGDI
                     IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEDAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKRY"
     gene            25453..25746
                     /locus_tag="VCX65_000933"
     CDS             25453..25746
                     /locus_tag="VCX65_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEP5053400.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRQRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG"
     gene            25743..26060
                     /locus_tag="VCX65_000934"
     CDS             25743..26060
                     /locus_tag="VCX65_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEP5053401.1"
                     /translation="MIRPTSYESLAALIEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFICVNRDQFIEVAQKWNIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            26078..26704
                     /locus_tag="VCX65_000935"
     CDS             26078..26704
                     /locus_tag="VCX65_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEP5053402.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEVSSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQIV
                     EMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELVLPNAPQKRGIIELDESAVVGEAFDPAKHWKG"
     gene            26856..27251
                     /locus_tag="VCX65_000936"
     CDS             26856..27251
                     /locus_tag="VCX65_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEP5053403.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISIVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(27512..28153)
                     /locus_tag="VCX65_000937"
     CDS             complement(27512..28153)
                     /locus_tag="VCX65_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEP5053404.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(28173..29150)
                     /gene="dusB"
                     /locus_tag="VCX65_000938"
     CDS             complement(28173..29150)
                     /gene="dusB"
                     /locus_tag="VCX65_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEP5053405.1"
                     /translation="MTKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELPDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFKTVR"
     gene            complement(29137..30009)
                     /gene="hslO"
                     /locus_tag="VCX65_000939"
     CDS             complement(29137..30009)
                     /gene="hslO"
                     /locus_tag="VCX65_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEP5053406.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIY
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNENDLEALINDKA"
     gene            complement(30156..31649)
                     /gene="rofA"
                     /locus_tag="VCX65_000940"
     CDS             complement(30156..31649)
                     /gene="rofA"
                     /locus_tag="VCX65_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HEP5053407.1"
                     /translation="MIEKYLESSIESKCQLIILFFKTSYLPITEVAEKTGLTFLQLNH
                     YCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSHDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRDLNHKHFHLFCHYIEQSLRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT"
BASE COUNT         9517 a         5739 c         6915 g         9658 t
ORIGIN      
        1 cgtaggttca aatcctgctc ccgcaataca taagtatgta gttgttggct cggtagctca
       61 gttggtagag caatggattg aagctccatg tgtcggcggt tcgattccgt ctcgcgccat
      121 taaaatttaa tattttacgg aaagatagcg aagaggctaa acgcggcgga ctgtaaatcc
      181 gctccttcgg gttcgggggt tcgaatccct ctctttccat cctaaacggg catagtttaa
      241 aggtagaact aaggtctcca aaaccttcag tgtgggttcg attcctactg cccgtgttag
      301 aaatatggcg ggtgtggtga agtggttaac acatcagatt gtggctctga cattcgtggg
      361 ttcgattccc atcactcgcc tattttattg gggtatagcc aagcggtaag gcaagggact
      421 ttgactccct catgcgttgg ttcgaatcca gctaccccag tttaaatttt atatttaaag
      481 ccggcgtggc ggaattggca gacgcgctgg actcaaaatc cagtgtccgc aaggacgtgc
      541 cggttcgacc ccggccgccg gtatacttga aaaacaaggt ttacaaacct tgttttttgt
      601 tttgatctta agctgtagct acgtagtaca atctcttata ttactgataa ggtctattta
      661 atgcgcaaga tttgtggtat gatgaatatg attgagtatt gatgctttat gggattaccg
      721 gtaaggtttt gaaaaaggtt tgtcactact aggtgctttt ttagctatag aaagacagtt
      781 atggattgat gtattgtaac taatgttgga ggttaatggt ggttgagttt tgagatattt
      841 acactgataa tcgggtggaa actggttggg tatcgggtaa tggagtgtgg ttcttcgttt
      901 aagcaaggag attatcgttt ggtggttcat atttgcttgt taaatgttag ggatgagatg
      961 ctgagtcagc aaggccatga agataaagct gactggccag agccttgaga tgtgacgttt
     1021 ggtggaagtc ctttttggtg agatggcaca gcatatagta atattagatc ctgaggaaga
     1081 attgggactt tcattaggct tgactggggt atgacctcac tttacaattc atttcgatga
     1141 tgggtttgat gatacgtttt tagttcagga ctttgtagag ttggagaatt tggttcttta
     1201 tgaggaagaa gtgcaggtaa ttcgttgaga cagtcgtgaa gatattttag gtatgattga
     1261 tgaaggtttg ttcattcctt atctgaagta taaaataaat ttgtgctttg agatggttgg
     1321 ccaatataaa gtccatcaat cttagaagta ataatttttg aattttttct gaggtttgtg
     1381 tatatttgat agtgtactga tgtaagaagt aaggagtact atgatggcaa tcaatgagag
     1441 agcttctgta aaaatcaagt taggccttga tactaagaat aagcgatgag atggttacca
     1501 cgatttatcg atggtcatga tgagtattga tctgtgtgac tatgtgacgg ttgaccatat
     1561 agatgacaat aagattgtct ttgcctcaaa ctgtccgaaa atacctatta actaagataa
     1621 tgatgtttat aagatagttc agctaatgaa acatcgattt caagttaaaa gaggagtttc
     1681 cgtttacttg gaaaagcgga ttcccatgtg tgctggtatg ggaggaggtt ctagcgatgc
     1741 tgttactatc agagcattaa atcagttatg gctccttact cttagccgaa aagatatgat
     1801 ggatattggt ataccgattg gtagtgatgt gccttattgc ttgctttcag gtcgtgccca
     1861 agtcactggt aaaggtgaag tggtttgtcg cattttgggg ctgttatcgt cttgggtggt
     1921 tttggttaaa ccagattttg gtatctcgac ttgaacattt tttctagata ttaattgtaa
     1981 aatcatttca agagtgtcta ctactcattt ggttgcggcg attgaagcgg gtaactataa
     2041 tgatgggata ttgactgaaa tgaacaattt gctggaagat attttcattg ccaagcgacc
     2101 ctttattcaa aaaataaaag agaaaacact gcaagctggt gctgctacta ctttgatgac
     2161 aggaagtgga ccgactgttt ttgctttgtg ccagaccgaa aaacaaacta taatagttta
     2221 aaaggacttt gcaaggaagt ttttaaggtg agaatgttgt aatattttgt tgggattgct
     2281 tctttggaag cttcatgtta taattaactg gttaatgaaa gaggagattt atggggactt
     2341 tagaaaaaaa acttgataac ttagtaaata ctattttatt aaaagcagaa aatcagcatg
     2401 agttattatt tggagcttgt caaagtgacg ttaagcttac taatacgcaa gaacatattt
     2461 taatgttact atctcagcaa cgtctcacta atacagattt ggctaaggca ttaaatatta
     2521 gtcaggcggc agtaactaag gctatcaaga gtttggtcaa acaagacatg ctagcaggaa
     2581 ctaaggatac ggttgatgct agggtgactt attttgaatt aaccgagtta gctaagccta
     2641 ttgcgtcaga acatacccat catcatgatg aaaccttaaa tgtttacaac cgtttattac
     2701 aaaaattctc cgcgaaagaa ttagagattg tagataagtt tgtaacagtt tttgctgagg
     2761 aattagaagg gtaatccatg agatacatat cagtgaaaaa tctctccttt caatatgaaa
     2821 gtgagccagt tttagaaggg atcacttatc atttagatag tggagaattt gtcaccatga
     2881 ccggtgaaaa tggcgctgca aagtcaacct taataaaagc aaccttagga attttacaac
     2941 caaaggctgg acgagttact attgctaaaa aaaataaaga cggtaaacaa ttaaggattg
     3001 cttacttgcc gcagcaagta gctagcttta acgctggttt tccatccacc gtttacgagt
     3061 ttgtcaaatc aggtcgctac ccacgtagtg gttggtttag acatttgaac aaacacgatg
     3121 aagagcatgt gcaagcaagc ttagaagcag tcggcatgtg ggaaaaccgt cataagagaa
     3181 ttggtagttt atcaggtggt caaaaacaac gtgtggttat tgcccgtatg tttgcttctg
     3241 accctgatat ttttgtgcta gacgagccaa caacgggaat ggatagcggt actactgata
     3301 ccttttatga actgatgcac cacagtgcac atcaacacgg gaaatccgtt ctgatgatta
     3361 cccatgaccc agaagaagtg aaggcttatg ctgatcggaa cattcattta gtcagaaacc
     3421 aaaaacttcc ttggcgttgt ttcaacattc atgaagttga aacagatgac gaaaaaggag
     3481 gtcatggtca tgcttgatat tttatcctat gatttcatgc aacgggcggt aatggcggta
     3541 gttgccatta gtatttttgc tccgatttta ggtattttcc ttattttacg tcgtcaaagt
     3601 ttgatgagcg atacccttag tcatgtttct ttggctgggg tagcgcttgg ggtagtcctt
     3661 ggtatttcac caaccatcac tactattatt gttgtggttt tagctgctat tttgttagaa
     3721 tacctgcgtg tagtttacaa acactacatg gagatttcaa cggcgatttt gatgtcactt
     3781 ggcttggccc tatctctgat tattatgagt aagtcgcata gttcatcaag catgagttta
     3841 gaacaatacc tttttggatc gatcatcacg attagtatgg aacaagttgt cgccttgttt
     3901 gctattgctg cgattatttt aatcttgacc gttctcttca ttagaccgat gtacattctg
     3961 acctttgatg aagatactgc ttttgtagat ggtttgcccg ttcgcttgat gtctgttcta
     4021 ttcaatatcg tcactggggt tgctattgct ttgaccattc cagcagcagg agcacttttg
     4081 gtttctacca ttatggtctt gccagcaagt atcgcaatga gattgggtaa aaactttaaa
     4141 acagttatct tactgggaat tgtcatcggt tttagcggta tgttatctgg tattttctta
     4201 tcttatttct ttgaaacgcc agctagtgcc actattacca tgattttcat tagtattttc
     4261 ctcttagtta gtctaggtgg aatgcttaaa aaacggttat tttaataaga aaaatcctca
     4321 catgtttaac atgtgaggat ttatttataa atgctttaaa aagggggtaa ggtcccaatt
     4381 ttcttgatta atggtgatgc tctcccaaaa gctatcatta gttaaacgag gaatcaaatg
     4441 aaggtgaaaa tgagtcccct catccatcaa ctccttgtca ttgctgacgc tagtgacgcc
     4501 tgaaatggga aggtgctgct ctagcttagc aactagagcg gcttgtaagt cgatgagatc
     4561 atagcgcact tcctttggta gttgtgtcag actagtgtaa tggtctttgg aaatcagtaa
     4621 aaggtgcccc ttttggatag gatcaatatc aaaaacaacc ttgaaatatt gactttgagt
     4681 cagtagctga tttgctttga gctgatggca aaagatacat tctgtcatag gtacatctcc
     4741 ttatgaaaaa acgagccaga gctcgtttaa tcggttatct agtaagtgag aacagcgtat
     4801 tttttcttac cgcggcgaat aacggttaat tgatcatcaa ttttatcatc attacttaat
     4861 tggtaatcta aatcttgaac gcggtctccg ttaatgtaga ttgctccatt ttgcacgtct
     4921 tcacgcgctt ggcgttttga tggggaaata cctgcggtga caagcatgtc aacaaggtta
     4981 aggctgtctt ctgattgaac gtgataattt ggtacattgc tcaatccttg ttttaattca
     5041 ttagcagaaa gatttttgat gtttccagca aataactgct cggtaatgtt aagagcttgt
     5101 ttataagctt cttcgccatg aaccaaggta accacttcgc gtgccaaggt tttttgagcg
     5161 agacgctcgt gacgagcggc attaaattga gtttcaattt ctgcaatctc atctagaaat
     5221 aagaaggtga agattttcaa gaaacgcact gcatcatcat ccatgacatt taaccagaat
     5281 tggtacatct cgtaaggaga cgtcttatcg gcatcaagcc agacggcatt accttctgat
     5341 ttaccgaatt ttttcccggt tgagtcagtg atgagtggta cagtcatgac gtgcccagtt
     5401 ttatcagcct ttttgcggag taattcagta ccagctgtca tattgcccca ctggtcagag
     5461 ccgccaattt gtaaggttac attatgcttg tcattgagtt cgtagaagtc gtagccctgc
     5521 atgatttggt aagcaaactc agtgtaagaa atgcctgttt caatgcgttt tttaacagag
     5581 tctttactca tcatgtagtt aacggtgaag tatttaccga catcacggag gaagtcaata
     5641 aagctgattt gcgagaacca gtcatagttg ttgacaagct ctgctttatt atcaccattt
     5701 tcaaaatcaa ggaaagtaga caactgccct ttaatcttgt cactccactc caaaactgtt
     5761 tctttggttt gaaggctgcg ctctgcatct ttaaaggaag gatcaccaat taaacctgtg
     5821 gcaccaccca caagagcgta aggtttgtgc cctgctagtt gcaagcgacg agatgttaag
     5881 atagccacta gatggcccag atgaaggctg tcagcggttg gatcataacc ggtataatag
     5941 gatacttgcc cttctgttaa tgctttgaca agggcttgtt catcagtcgt ttgaaagacc
     6001 aagccacgag ctttgagttc ttcaaaaata ttcataggct ttctccattt tcattatagt
     6061 ttcgaatcat tatatcaaaa aacgctactg ctatgcaagc tttatcaaag tttggtataa
     6121 tgataaatga ggtattttat ggtgaaatgg aacacgaaac aaaagcgtat aagtcatcaa
     6181 agattaggtc tcttggattt ggggccggtg ctattacgta cgttgagact actgtctaac
     6241 tttttttata ttgttatctt cctttttgga atgatgggat ttggtatggc atttgggtat
     6301 ttggctagtc agattgaatc tgttaaggta ccaagtaaag aaagtttagt caaacaagtt
     6361 gaatcattaa cgatgatttc gcaaatgaac tattctgata atagtttaat ttctacttta
     6421 gatacggatt tacttcgaac accagtagct aatgatgcga tttcagagaa tatcaaaaaa
     6481 gctattgtat caacagaaga cgaacatttt caagaacata aaggtgtcgt gccaaaagct
     6541 gtttttcggg caacattggc ttctgtattg ggatttggag aagctagtgg aggttcgacc
     6601 ttaacacagc aattggtcaa acaacaagtt ttgggagacg atcccacatt taagcgcaag
     6661 tctaaggaga tcgtttacgc tcttgcctta gagcgttata tgtccaaaga caatatctta
     6721 tgtgattatc ttaatgtttc accttttggt cgtaataaca agggccaaaa tattgctggt
     6781 gttgaagaag ctgcgcgtgg catttttggc gtttctgcca aagatttaac ggtgccacag
     6841 gcagcatttt tggcggggct tccgcagagt cctattgttt actctcctta tttgtcaacg
     6901 ggacaactga agtcagaaaa ggacatggct tatggcatca agcgtcagca aaatgttctc
     6961 tataacatgt accgtacagg tgttctgtct aaaaaagaat acgaggacta taaggcttat
     7021 ccgattcaaa aggattttat tcaaccggga agcgcaatag taaataatca cgattacctt
     7081 tattacacgg tgttagcgga tgctaaaaaa gccatgtata gctatttgat taagcgagat
     7141 aaggtgtcta gtcgtgactt gaaaaatgac gagactaagg ctgcttatga agagagagcc
     7201 ttaacagaat tgcaacaggg tggctatacc atcaccacaa ccattaataa gcctatttac
     7261 aatgcgatgc agacagcggc agctcagttt ggtggcctgt tagatgatgg cactggtaca
     7321 gttcaaatgg gaaatgtctt gacagacaat gcgactggtg ctgtgttagg ttttgttggt
     7381 ggtagagatt atgctctgaa tcaaaataat catgctttca atacaattag atcgccaggt
     7441 tctagcatta aaccgataat cgcttatggt cctgctattg atcaaggttt aatggggagt
     7501 gctagcgttt tgtctaatta cccaacaact tactcgagtg gccaaaaaat catgcatgct
     7561 gatagtgaag gaacagccat gatgccactt caagaggccc taaatacttc ttggaacatc
     7621 ccagcttttt ggacacagaa attactgcgt gaaaaaggtg tcgatgtcga aaattatatg
     7681 acaaaaatgg gttataagat tgcagactac tcgattgaaa gtttacctct agggggcggt
     7741 attgaagtct cggttgctca acaaaccaat gcttaccaaa tgctttcaaa caatggctta
     7801 tatcaaaagc aatatattgt agataagatc actgctagcg atggtacagt cgtttacaaa
     7861 catgaaaata agccaattcg tattttttct gcagcaacag ctacgatttt acaagaattg
     7921 ttgagaggtc cgattacttc aggcgctacg actactttca agaaccgttt ggcggctatt
     7981 aatccgtggc ttgctaatgc tgattggatt ggtaagaccg gaacaactga gaattatacg
     8041 gatgtttggc tagtcctgtc tactccaaaa gttaccttag gcggttgggc aggacatgat
     8101 gacaatacct cattagcgcc attaacagga tataacaata attctaatta ccttgcctat
     8161 ttagctaatg ccattaatca ggccgattcc aatgttattg gagtagggca acgtttcaac
     8221 ttagatccag gagtcattaa ggcgaatgtc ttgaagtcaa caggtttaca accaggaact
     8281 gttaatgtca atggacatac tttttctgtt ggtggagaaa tgaccaccag tctatggtcc
     8341 caaaaaggac cgggggctat gacttaccga tttgctattg gtggcacgga tgccgattat
     8401 caaaaagctt gggggaactt tgggttcaga aaaaattagg ttgccattta tcgataaaaa
     8461 gggtataata gcaataacta tttgtcgtcc aatctagctg aaatattgtc cagttaggaa
     8521 gaacagcagt taaatcacac tgataaagtc agatttagct gctctttttg tgtctatttt
     8581 tagaaaagat agggtttgta acctatattt aaatattcta aaaattaaca tttagggcaa
     8641 atgataactt agttgcgatt tgctgaaaca gcaaagctta aatagaagaa ggagctaaaa
     8701 acttggcagg acatgaagtt cgatacggaa aacaccgtac acgtcgtagc ttttcaagaa
     8761 tcaaagaagt tcttgattta ccaaatttga ttgaaattca aactgactca ttccaagatt
     8821 tcctcgattc aggtttgaaa gaagtatttg aagatgtact tcctatttca aactttacgg
     8881 atactatgga acttgaattt gttggttacg aatttaaaga acctaaatat acccttgaag
     8941 aagctcgtat ccacgatgca agttattctg caccaatctt tgttaccttc cgtttggtca
     9001 ataaagaaac tggtgagatt aaaactcaag aagtcttctt tggtgatttc ccaatcatga
     9061 cggaaatggg tacctttatt atcaatggtg gtgaacgtat catcgtttct cagttggtgc
     9121 gttctccagg tgtttatttc aacgataaag ttgataaaaa cggtaaagtt ggttacggat
     9181 caacagtgat tcctaaccgt ggggcttggt tggaattaga gactgactca aaagacattg
     9241 cctacactcg tattgaccgt acgcgtaaga ttccattcac aaccttggtt cgtgcccttg
     9301 gtttctcagg tgatgatgaa attgttgata tctttggtga aagcgacctt gttcgtaata
     9361 ccattgaaaa agacattcac aaaaatccaa gtgattctcg tacagacgaa gcccttaaag
     9421 aaatttacga gcgtcttcgt ccaggtgagc caaaaactgc agatagctct cgtagtctct
     9481 tgattgcgcg tttctttgat gcacgtcgtt acgatttggc tgcggttggt cgttacaaag
     9541 tgaacaaaaa acttaatatc aagactcgtc ttttgaacca aatcattgct gaaaaccttg
     9601 tggatgctga aactggcgaa attttggtag aagctggaac tgagatgact cgtagcgtca
     9661 tcgaatccat cgaagaacac cttgacggtg atttgaacaa gtttgtttac acaccaaatg
     9721 attacgctgt ggttactgaa cctgttgttc ttcaaaagtt caaggttgtg tcaccaattg
     9781 atcctgatcg tgtagtaact attgttggta atgccaatcc agatgataag gttcgtgcat
     9841 tgacacctgc tgatattttg gcagaaatgt catacttctt gaaccttgct gaaggtcttg
     9901 gaaaagttga cgatattgac cacttaggta accgtcgtat ccgtgccgtt ggtgaattgc
     9961 ttgccaacca attccgcatc ggtcttgctc gtatggagcg taacgttcgt gagcgtatgt
    10021 ctgttcaaga caacgatgtg ttaacaccac aacaaatcat caatatccgt cctgtcacag
    10081 cagctgtcaa agaattcttc ggttcgtctc agttgtcaca gttcatggac caacacaacc
    10141 cattgtcaga gttgtctcac aaacgtcgtt tatctgcctt aggacctggt ggtttgacac
    10201 gtgaccgtgc tggttatgag gttcgtgacg tgcattacac gcactatggc cgtatgtgtc
    10261 cgattgaaac acctgaagga ccaaatattg gtttgattaa caacttgtct tcatttggac
    10321 atcttaataa atatggtttc attcaaacac cttaccgtaa ggttgaccgt gcgactggta
    10381 gggtaactaa cgagattgtt tggttgactg ccgacgaaga agacgaatac acagttgcac
    10441 aggccaattc gaaactaaac gaagatggca cttttgctga agaaatcgtt atgggtcgtc
    10501 accaaggtaa taaccaagaa ttttctgcaa gtgttgttga tttcgttgac gtttccccta
    10561 aacaggtagt tgctgttgcg acagcatgta ttcctttctt ggaaaatgat gactccaacc
    10621 gtgctctcat gggtgccaac atgcaacgtc aggctgtgcc attgattgat ccaaaagcac
    10681 catatgttgg tactggtatg gaatatcaag ctgcccatga ctcaggcgct gcggtgattg
    10741 ctcagcacaa tggtaaagtt gtcttttctg atgctgaaaa agtggaaatc cgtcgtcaag
    10801 atggctcact tgatgtttac cacattacca aattccgtcg ttcaaactca ggaacagcct
    10861 ataaccaacg cacccttgtt aaagtaggag acattgttga aaaaggtgat ttcatcgctg
    10921 atggaccttc tatggaaaat ggtgaaatgg ctcttggaca aaacccagtc gttgcttaca
    10981 tgacttggga aggttataac tttgaggacg ctgttatcat gagtgagcgc cttgtgaaag
    11041 aagatgtcta cacatctgtt cacttggaag aattcgaatc tgaaacgcgt gatacaaaac
    11101 ttggccctga agaaatcact cgggaaatcc caaatgttgg tgaagaagcc ctcaaagacc
    11161 ttgacgaaat gggaattatc cgtatcggtg ctgaggttaa agaaggcgac atcttagtag
    11221 gtaaagtcac acctaaaggt gaaaaagacc tctctgctga agaacgttta cttcacgcca
    11281 tctttgggga taaatcgcgt gaagtgcgtg atacctcact tcgtgtccct cacggtggtg
    11341 atggtatcgt tcgtgatgtg aaaatcttta cacgcgctaa cggcgatgaa ttgcaatcag
    11401 gtgttaatat gcttgtgcgt gtttacatcg ctcaaaaacg taaaatcaag gtcggagata
    11461 aaatggccgg tcgtcacgga aacaagggtg tcgtttcacg tattgtacca gttgaagaca
    11521 tgccatacct tccagacgga acaccagttg acatcatgtt gaaccctctt ggggtgccat
    11581 cacggatgaa tattggtcag gttatggaac ttcaccttgg tatggctgct cgtaatcttg
    11641 gcattcacat tgcaacacct gtctttgacg gggcttcatc agaagacctt tgggacactg
    11701 ttcgtgaagc tggtatggat agcgatgcta agacggtcct ttatgatggt cgcaccggtg
    11761 aaccatttga caaccgtgta tccgttggtg tcatgtatat gatcaaactt caccacatgg
    11821 ttgatgataa acttcatgcc cgttctgtag gaccatactc acttgttacc caacagccac
    11881 ttggtggtaa agctcaattt ggtggacaac gttttggtga gatggaggtt tgggcccttg
    11941 aagcttatgg tgcatcaaat gttcttcaag aaatcttgac ctacaagtca gatgacgtca
    12001 caggacgttt gaaagcctat gaagcgatta ctaaaggtaa accaattcca aaaccaggtg
    12061 taccagaatc cttccgtgtt cttgtaaaag aattgcaatc gcttggtctt gatatgcgtg
    12121 tgcttgacga ggatgataat gaagtggaac ttcgtgatct tgatgaaggt gaagacgatg
    12181 acattatgca tgttgacgat ctcgagaagg cacgtgaaaa acaagctcaa gaaacccaag
    12241 aagtttctga aacaactgac gaaaaataag caatcaattc ttattaaata attatttact
    12301 ggtctggggc aaaggcccca ggaactggta aagtcatcaa aggcagaaag gtaaaactag
    12361 tggttgacgt aaatcgtttt aaaagtatgc aaatcacatt agcctcacca agtaaggtcc
    12421 gttcatggtc ttatggtgaa gttaaaaaac ctgaaacaat caactaccgt acattaaaac
    12481 cagaacgtga aggactcttt gacgaagtca tctttggtcc aacaaaagac tgggaatgtg
    12541 cgtgtggtaa gtacaaacgt atccgttata aagggatcgt ttgtgaccgc tgtggggttg
    12601 aggtaactcg tgctaaagta cgtcgtgaac gtatgggtca cattgagtta aaagctcctg
    12661 tatcacatat ctggtatttc aaagggattc catctcgtat gggattgact cttgatatga
    12721 gtcctcgtgc ccttgaagaa gtgatctatt ttgcggctta tgtggtcatt gatccaaaag
    12781 atacaccgct tgaaccaaaa tcattattaa cagaacgtga ataccgtgaa aaactacaag
    12841 agtatggtca tgggtcattt gtcgctaaga tgggtgctga agccattcaa gatctcttga
    12901 aacgtgtgga cttggcagct gaaatcgctg aattaaaaga agagttgaaa tctgcttctg
    12961 gtcaaaaacg gattaaagca gttcgtcgtt tagacgtcct tgatgccttt aacaaatctg
    13021 gaaataaacc agaatggatg gttcttaaca tcctgccggt tattccacca gatcttcgtc
    13081 cgatggttca attggatggt ggccgttttg cggcatcaga cttgaatgac ttgtaccgtc
    13141 gtgtgattaa ccgtaataac cgtttggcac gtttgttaga acttaatgcc cctggcatca
    13201 ttgttcaaaa tgaaaaacga atgcttcaag aagccgttga tgctttgatt gataatggtc
    13261 gtcgtggtcg tccaatcact ggaccaggaa gtcgtccatt gaaatcattg agccacatgc
    13321 ttaaaggtaa acaagggcgt ttccgtcaaa acttgcttgg taaacgtgta gacttctctg
    13381 gacgttccgt tatcgctgtt ggtccaaccc ttaaaatgta tcaatgtggt gtcccacgtg
    13441 aaatggctat cgagcttttt aaaccatttg taatgcgcga aattgttgcc aaagaatatg
    13501 ctggtaacgt taaagccgct aaacgtatgg ttgaacgtgg cgacgaacgc atctgggata
    13561 tcttagaaga agttatcaaa gaacacccag tcctacttaa ccgcgcaccg acccttcaca
    13621 gacttggtat tcaggctttt gaaccggttc ttattgacgg taaggcactt cgtcttcacc
    13681 cacttgtgtg tgaggcctac aatgccgact tcgatggaga ccaaatggcc atccacgtgc
    13741 cactttcaga agaagcacaa gctgaagctc gtcttttgat gcttgctgca gagcacatct
    13801 tgaaccctaa agatggtaaa ccagttgtta ctccatctca ggatatggtt cttggtaact
    13861 actatcttac gatggaagat gctggtcgtg aaggcgaagg tatgattttc aaggataaag
    13921 acgaagctgt gatggcatat cgtaatggtt atgctcatct tcatagtcgt gtgggtatcg
    13981 ctgttgacag catgccaaac aaaccttgga aagacagtca aagacataaa atcatggtga
    14041 caactgttgg taagattctc tttaacgata tcatgccaga ggaccttcct tacctccaag
    14101 agccaaacaa tgccaacttg acagaaggaa cacctgataa atacttcctt gaacctggtc
    14161 aagacatcca agaagtgatt gatcgcttag acatcaatgt gccatttaag aagaaaaacc
    14221 tcggtaacat cattgcggaa accttcaaac gtttccgtac aacagaaaca tcagccttcc
    14281 ttgaccgctt gaaagacctt ggttactacc attcaaccct tgccggtttg acagtgggta
    14341 tcgctgacat cccagttatc gataacaaag cagaaatcat tgatgctgct caccatcgtg
    14401 ttgaagaaat taacaaagcc ttccgtcgtg gtttgatgac agatgatgac cgttatgttg
    14461 ccgttacaac aacatggcgt gaagctaaag aagcccttga aaaacgtcta attgaaacac
    14521 aagatcctaa gaacccaatc gttatgatga tggactcagg agctcgtggt aacatctcta
    14581 acttctcaca gcttgctggt atgcgtggtt tgatggctgc tcctaacgga cgcatcatgg
    14641 aacttcctat cttgtcaaac ttccgtgaag gtttgagcgt tttggaaatg ttcttctcaa
    14701 cccacggtgc acgtaaaggg atgaccgata cggcccttaa aacagccgac tcaggttatc
    14761 ttactcgtcg tttggttgac gttgcccaag atgttatcat tcgtgaggac gattgtggca
    14821 ctgatcgtgg tcttcttatc cgtgctatta cagatggtaa agaagttacc gaaacgcttg
    14881 aagagcgtct tcaaggtcgt tacacacgta aatcagtcaa acaccctgaa actggtgaag
    14941 tcttgattgg tgctgaccaa ttaatcactg aagacatggc tcgtaagatt gttgatgcag
    15001 gtgttgaaga agtgaccatt cgttctgtct ttacctgtgc gactcgtcat ggtgtctgcc
    15061 gtcactgtta tggtatcaac ttggcaactg gtgatgctgt tgaagtgggt gaagcagttg
    15121 gtactattgc tgcccaatct atcggtgagc ctggtactca gcttaccatg cgtaccttcc
    15181 acacgggtgg tgtagcctca aataccgata tcacacaggg tcttcctcgt attcaagaga
    15241 tctttgaagc acgtaatcct aaaggggaag cggtcattac tgaagtgaaa gggaatgtcg
    15301 tcgagattga agaagatgcg tcaactcgta ccaagaaagt ctacgttcaa ggaaaaactg
    15361 gcatgggcga atatgtcgta ccatttacag cacgtatgaa agttgaagtt ggcgacgaag
    15421 ttaatcgtgg agctgccctt acagaagggt caattcaacc gaaacgtctc cttgaagtgc
    15481 gtgatacctt gtcagttgaa acgtaccttc ttgcagaagt acaaaaagtt taccgtagcc
    15541 aaggggtaga aatcggagac aaacacgttg aggtaatggt tcgccaaatg cttcgtaaag
    15601 ttcgtgtcat ggatccaggt gatacagacc tccttccagg tacacttatg gatatttctg
    15661 atttcacaga tgctaacaaa gatattgtta tctctggtgg tattcctgcg acatctcgtc
    15721 ctgttcttat gggtattact aaggcttccc ttgaaaccaa ttccttctta tcagctgcat
    15781 ccttccaaga aacaactcgt gttcttacag atgctgctat ccgtggtaag aaagaccact
    15841 tacttggtct taaagaaaat gttatcattg gtaaaatcat tccagctggt actggtatgg
    15901 cgcgctaccg taacattgaa ccacaagcga tgaatgagat tgaagtgatt gatcatacag
    15961 aagtctcagc agaagccgtt tttacagcag aagcagaata atctcatgaa agagtcctta
    16021 ggggctcttt tttgtctgag tttgttggca gtaaaaagca ttgacaatca gtcttagtcc
    16081 caatgagcag atgtttttca aaatacttat gatttagcta taataatgca taagaggaat
    16141 aggtaatgtg ttatgtatca agtaattaaa atgtatggtg attgggagcc ttggtggttc
    16201 atcgatggat ggcaagacga tattatagat gagcaacaat ttagtgactg gcaagaagcg
    16261 cttgattatt ttaatcaaga atggcagcgc atgaaagcta tttttcctag ttatcatagt
    16321 caaaagaatt tgttagctac tttttgggaa aaagaagata aaagatggtg cgaggactgt
    16381 gacgaagatt tacagcagtt tcattctctt ttactcctta aaaataaaga tattgtacca
    16441 agcaataatt atatccctga atttgaacaa cgaaatgatt caccacaggt agcttatctt
    16501 tgcaagttaa acctttaagt gtttgttaaa aacaaaataa gttaaaagaa aatatcactt
    16561 cttctgatat tttctttttt tgtttacgaa taaatgagta aggaggaatt atggtacaag
    16621 cattagcaaa agctattcta gcaaaagctg aacaggttca ggcacaagat atttatattt
    16681 tgccaagagc agatcaatat gatctttttt tacgaatagg agatgaaagg agattagttg
    16741 atgtttatca gagcgatcgg atggctcctc ttattagtca ctttaaattc gttgcaggaa
    16801 tgatagttgg tgaaaagaga cgttgtcagg tgggttcatg tgattataag cttagtaaag
    16861 ataagcagtt atctttgcgc ttatctagcg tgggtgatta tcgcgggcaa gaaagcttag
    16921 tgattcgtct gcttcatcat caaaataaaa gtgtacatta ttggtttgat ggattgacaa
    16981 aagtagccaa tcaggttggc ggtagagggt tgtatttatt tgcaggacca gttgggtctg
    17041 ggaagacaac cttgatgtac cagctgattt cgagttatca tcaagaagca caggttatta
    17101 gtatagaaga tcctgtagaa attaaaaatc accagatttt acaattacaa gtgaatgatg
    17161 atattggtat gacttatgac aatttgatca aactgtcttt acgccatcga ccagatattt
    17221 tagttattgg tgagattcga gatagtcaaa cagcaagagc cgttattagg gctagtctaa
    17281 caggtgccat ggttttttca acggttcacg ctaaaagtat ctcgggtgtt tatgtaagat
    17341 tgttagaact tggtgtaacg aaagcagaac tgtctaattg cttagcatta attgcttacc
    17401 aaaggttact taatggagga gcattgattg actctactca aaacgaattt gaatattatt
    17461 cctcatcgaa ctggaatcaa caaattgatc agcttcttga ggcaggacat ctcaatccca
    17521 agcaagctaa gcttgaaaaa attatctagt aaacatcagc ataaattcat tcaattacta
    17581 gctaatcttt tatctacagg atttagcttc gcagaggtta ttgctttttt aaaaagaagc
    17641 cagttgcttc agctagatta tgttcttaaa atggaagagt ctttattaaa aggacaagac
    17701 ttagcagata tgttgtcggg tttaggtttt tcagatgcta ttcttactca aattagttta
    17761 gctgatagac acggtaatat tgaaacaaca ttagtagcga ttcaacatta cttgaaccaa
    17821 atggcaagga tcagacgaaa aactgttgaa gttatcacct atcctcttat tcttttactt
    17881 tttctttttg tgatgatgct agggttgaga cgctatttag tccctcaatt agaaactcaa
    17941 aatcagataa cttactttct taaccatttt cctgccttct ttataggttt ttgctcaggt
    18001 cttattttgt tgttcgggat ggtatggcta cgatggcgat ctcaaagccg cttgaaactc
    18061 tatagtcggc taagccgtta tcctttttta ggtaaactgt taaaacaata cttaactagt
    18121 tattatgcta gagaatgggg tacgttaata ggtcaaggtc ttgatttgat gactatttta
    18181 gacattatgg ccattgagaa atcctcacta atgaaagaat tagctgagga catcagaatg
    18241 agtctgcttg aagggcaagc ctttcacatt aaagtagcta cctacccttt ttttaaaaaa
    18301 gaattaagtt taatgattga atacggtgaa atcaaatcga aactgggggc tgagttggaa
    18361 atctatgccc aggaaagctg ggaacaattt tttagtcagc tttatcaagt gacacaactt
    18421 attcaaccag ctattttttt agtagttgct gtgacaatcg tcatgattta tgcggcaatc
    18481 ctattaccaa tttaccaaaa tatgggaggt attttttaag atgattaatc aatggaacaa
    18541 cttacgacac aagaagctaa aaggatttac tcttctagaa atgttattgg tgattcttgt
    18601 catcagtgtt ttgatgctat tatttgtgcc taatttaagc aagcaaaaag acagggttac
    18661 agaaacaggt aatgccgctg ttgttaaatt agtggagaat caagcagaac tatatgaatt
    18721 atctcaaggc tcaaaaccaa gtttgagcca gttaaaggca gatggtagta tcactgagaa
    18781 acaagaaaaa gcttatcaag actattatga caaacataaa aatgaaaaag cccgtcttag
    18841 caattaaagc ttttactttg cttgaaactt tactaagttt gtcagtgatg agtttcatta
    18901 tattgggatt gtctgtacca gtgacaaaaa gctatcaaaa agtagaagag catctgtttt
    18961 ttagccattt tgaacatttg tatcgacatc agcaaaagtt agccatatta cagcaaaaac
    19021 agcgcgtctt ggatatttct tcaacaaaaa ttgttacaga aggtaatagc ctaacagttc
    19081 ctaaatcaat aacagtgaat catccttatc ggttagttat tgatcagatg ggaggcaacc
    19141 attccttagc taaaattatt tttgacatga ctgatcgacg ctttaaatac caattttatc
    19201 tagggagtgg gaattatcaa aaaacaagtc aaagcttaca tagcccttga aagtatgatc
    19261 gcaacaggca tcctctttag tattgtcatt ctcgtcttaa gcagtttaca gcagagtcag
    19321 gctgctctaa cgtactatcg aaagcagcaa gaaaagctta atctagcctt gatggcagta
    19381 caaactagaa ctaaagagat aacattgaat ggttgtcata ttactatttt acgtacggat
    19441 agatacatta gtattcacga tgacgaagga gaagtgatga agattgagta aacaattaag
    19501 taacataaaa gcttttaccc ttctagaggc gttaatagcc ttactcgtga tatcagggtc
    19561 tttattggtt tatcaaggtt tgacccaaac cctccttaaa cgtagccatt atctagcccg
    19621 tcatgatcaa gacaattggc tcttattttc tcatcaattg cgagaggagt taagtggagc
    19681 aagattttac aaagtagctg ataataaact atacgttgaa aaaggaaaga aagtactagc
    19741 ttttggccaa tttaaaagtc atgattttcg aaaatcagct agtaatggaa aagggtatca
    19801 acccatgtta tttggaatat cacgtagtca tattcacata gagcagtcac agatttgcat
    19861 tactttaaag tggaaaagtg ggttagaaag gactttttat tatgcctttc aagactaatc
    19921 tcaaagcagg catccttttg tatgctatgt ttatggctag tatttttttg ctggttttac
    19981 aggtttacct ttctcaagtg acagctctac acaaggaata ccaagctcaa actgactatg
    20041 ttaaagcccg actgatagca gaaatagttt atcaagatca tagatataaa gcttctaatc
    20101 ctgtcttttt taaaggtggt caagtcattt gtcgagagcg aaaagagaga tggatgttaa
    20161 ttgttaagtt agatcagcaa cgacagtatc agtttgaata ccttaaaccc aaacaatata
    20221 gtcaataaat agtattgttg tcataaatcc ataaaatgat ccaatatata gtaattaaag
    20281 gtgacacttc ttttcatttc aagtgtaatt tggtatgata aggttatgac ttttgaaaaa
    20341 attgaagaag cttatcagct gctcttagag aactgtcaac taattgaaaa tgatctaaaa
    20401 acacatatat acgatgccat tgttgaacaa aactcctttt atttaggggc tgagggagct
    20461 agtcctcaag ttgctcaaaa tagtgataaa ctgaaagcct tgtgcctgac aaaagaagaa
    20521 tggcgtaagg cctaccagtt tctttttatt aaggcagctc agacggagca actccaagcc
    20581 aaccatcagt tcacaccaga tgctattggc ttcattctgc tgtatctttt ggaacaattg
    20641 agtgataaag atagcttaga ggtacttgag attggaagtg gaacagggaa cctagcccaa
    20701 acccttctca acaacacgag caagagcctt gattatgtag ggattgaact tgatgatctc
    20761 ttgattgatc tgtcagccag tattgctgag ataatggatt cttcagctca ttttattcaa
    20821 gaagatgcgg taaggcctca attactaaaa gaaagtgaca ttgtcatcag tgacttacca
    20881 gttggttatt atcctaacga tgatattgcc aaacggtaca aggtggctag ttcagataag
    20941 catacctatg cccatcattt attaatggaa cagtctttaa aatacttgaa aaaagacggt
    21001 tttgcgattt ttctggcacc agtcaattta ttgacgagcc ctcagagcca gttattgaaa
    21061 cagtggttaa aagattatgc tcaggtggtg accttgatta cgctaccaga ttctattttt
    21121 ggtcatccct caaatgccaa gtccattatt gtcttacaaa aacaaacaga ccacccaatg
    21181 gaaacctttg tctatccaat tcgggatttg aagcttgcag agaatattca tgattttatg
    21241 gaaaatttca aaaaatggaa actgagtaat gtcaattaat tgattttttg ttataataaa
    21301 aaaacatcac agaaaacgat ttcaagagag gttaaaaatg tcaaagacaa ttgcaattaa
    21361 tgcaggtagt tctagtttaa aatggcaact ttatcagatg ccagaagaag aagtgttagc
    21421 acaaggaatt attgagcgta tcggtctcaa ggattctatt tcaacagtta agtacgatgg
    21481 caaaaaagaa gagcaaattc ttgatattca cgatcataca gaagctgtta aaatcttatt
    21541 gaacgatttg attcactttg gaatcattgc agcttatgat gaaattacag gagttggaca
    21601 ccgtgttgtt gctggtggtg aacttttcaa agaatccgtt gtggttaatg acaaagttct
    21661 tgaacagatt gaagaattat ccgttttagc tccacttcac aatcctggag cggcggcagg
    21721 gattcgtgcc ttccgtgata ttttgccaga tattaccagt gtttgtgtgt ttgacacgtc
    21781 atttcacact agcatggcaa agcatactta cctttaccca attcctcaaa aatattatac
    21841 ggactacaag gttcgtaaat atggggcgca tgggacaagt cataaatatg tagcgcaaga
    21901 agctgctaaa atgcttggtc gtccattaga agaattaaaa ctaattactg ctcatattgg
    21961 aaatggtgtc tcaattacag ctaattacca cggtaaatca gttgatacct cgatgggctt
    22021 tacaccactt gctggtccta tgatgggaac acgttctggt gacattgacc cagctatcat
    22081 tccttattta attgagcaag acccagaatt aaaagacgct gctgacgttg tgaatatgtt
    22141 aaacaaaaaa tcaggtctta gtggggtgtc aggcatttct agtgatatgc gtgatatcga
    22201 ggctggttta caagaagata atccagatgc tgttttagct tacaatatct ttattgatcg
    22261 cattaaaaaa tgcattggtc aatatttcgc tgttttgaat ggagcagatg ctttggtctt
    22321 tacagctggt atgggtgaaa atgcaccatt gatgcgtcaa gatgttattg gtggcttaac
    22381 atggttcgga atggacattg atcctgagaa aaatgttttt ggataccgtg gtgaaatttc
    22441 aactcctgag tcaaaagtga aggttcttgt tatctcaaca gacgaggaat tgtgcatcgc
    22501 gcgtgacgtt gagcgtttga aaaatacaaa ataaaagaga ctaagttttc atagattaac
    22561 caagtaaggc aacactttac ttggtttttt atgaggttta tctgttagtt atggtgccta
    22621 ggtattagtt ctgatcagtc tccttgcttt ttgtaatctt gtgctaggcg atttggatgt
    22681 cagccttatt tagaagtttt taattgcttc aacgcttttc ttgtatgtgt ttatagagcc
    22741 caatgatcta aaagactatt tgataacggt ttatgatgag cgtaatcgtg cgattcgaaa
    22801 acagacacaa gtttactgct tttacctgat gattgttcta tttgttgcct tattcttttt
    22861 cttcccttgc ttaaccattc gagaccttgt ttcttataag ctagctttga tttttgctta
    22921 cctttacttg attatcagaa gtctggtggc taagaaaatg gaggcactag ggaaaataac
    22981 aactaatagt caaaaacctc cgtttgatac gagtcaggtt ctttgttaga tgacttgtct
    23041 aacggttgag tttcctgtct ggtcaacgga ggtgtttgta ttgttgtctg atttgtattg
    23101 gggcacttat tttacaagct tttagcctta tcgatggttt tgtcaatggc agagctgaca
    23161 gtagttgtga ggccaaggcg ttctaactcc attagaccag caatagttgt gccaccgggg
    23221 ctacaaatag cgtcaatgaa atcgtgcgga ctttgagaac tggtcttgag attgctggcg
    23281 ctagccaaga ctgtttgagt aacaatctcc agcgcctttg ctttaggcat gccattcttg
    23341 acgccagcct tagccaaagc ctcaataaag agataaatat aggcaggact tgaccctgct
    23401 aaagcggtaa aggtgtcaaa atccttttca ctaatatcaa atgtgctacc aaagctatct
    23461 gttaagtttc gaacacgtgc ttgtaattcc tgggacacca aagcatttcc cgttaaagcg
    23521 gtactgcttt ggagaatttg tgcattcata tttggcatga tacgtagcag cggaaggtct
    23581 tgtcctacga atgttgctag tcgttgaagg gaaatgcctg ctgccataga tataataggc
    23641 tgtttgaagt gaagcggttt gagtaccgtt tcaaatagtt gaggcttgat gcctaaaata
    23701 acaagatcaa cctggtcaat aaggtcttgg tgggacatag cataaggcag tgttaactgc
    23761 tctgcaattt ccttggaccg ttctaaagat gatcctgaaa tgataagttc atggggtgtt
    23821 tgtttaaggc ctttgatgat agcgctagcc attttgccaa caccaataat gccaattttc
    23881 attctgttgc tccttgtggg atattacggt taatcaggct aacgctagtt tagtaacgtt
    23941 taatcaagtc aacggttgag cgatccagtt ttttgataat ggcttgtaag aaggcttggg
    24001 cttctacgaa atcatccata gcgtagaggg tttgatgaga gtgaatgtag cgtgcacaga
    24061 ctccgatggt tgttgatggg acaccaccat tttgaaggtg tgcagcacct gcatctgtgc
    24121 ctcccttgcc acaatagtat tggaaattga caccagcgtc ctcagcagta gtcagtaaga
    24181 agtcgcgcat atctttgagc atgacatggc ctgggtcgta aaagcgcaat aaggtaccat
    24241 ctccgattgt tccaggattg ccataaatat caccagcagg cgaacaatct actgcgaaaa
    24301 agagttcagg gtcgaacttg gtggttgaga cgtgggctcc gcgcagacca acttcttctt
    24361 gaacgttagc acctgcaatt agggtgttgt taaggtcttg tccttttaac gcttcaagca
    24421 tttctgttat catgagaacg ccatagcgat tgtcccaagc ttttgaaata atattttttt
    24481 gattggctgt taggatcgtt tcagattgag ggacaataat atcacccggt gtaatgccaa
    24541 agctttcagc ttctgcctta tccgtaaagc caccatcaaa cacaatattt tcgatatttg
    24601 gtagactagc agagccattt gccccacgta aaaaatgggg aggtaccgat cctgaaataa
    24661 ggggaataac ttggccagtg cgtgtgtaaa gggtaaaccg ttgtgaactg acaacaagtg
    24721 ggttccaacc accgatacca accacgcgta gcgttccgtc aactttgata tcactgacca
    24781 taaaaccgac ttcgtccatg tgcgcagcta ctaaaatacg gggggctttt tcagctttac
    24841 tatctctgat accaaaaatg ccaccaagcc cgtctgtttc aacacggtca accagcgggg
    24901 ttattttggt gcgtaggtag tcacgaacgc tatgttcata gcccgcaatg ccatccagtt
    24961 cggtaacttc tttgattttt gagaataagt ctgtcatttt tcatctccat ttaaaaggtt
    25021 tcagaccagt tcaacgcggt catctcctta tattctacca ctttttaagt aagaatgggt
    25081 ttcacagaaa agaaaaatcc cagagactag agatctctgg aagaagtgtt tgtcttttgg
    25141 cgataacctg tttttttagg cagcaaggaa atcattaaaa tgataaagca caagctggtt
    25201 aataagaata gtagggcgct taggatgcga aaagactctt cactagcgaa aagtaaggat
    25261 aatggagtca taaggagaac cttccatttt aggttaatca gtatttttta tagcgtggtt
    25321 aaattaataa taaaccacac ctaatcaatg tacttttagt ttagttgttt ttactatttt
    25381 tgtcaataca taacagtaga aatctttagt tttcttattt cagatcgtcc aatttgatct
    25441 ttttatgata aaatgaggga tatgagtaaa aagaaaatag gtatgatttc aggtatcttt
    25501 ggatttagtt tagctattgg cctgggaata gttatcaaag attattgcca agacaggcag
    25561 cgccgacaaa tgacaaggga tttacgcacc tttttttcac ctttaggaca aatcgaagtt
    25621 ttatatatca atccttgtca ggtcaaacaa gattatattt caggtggggt tgttatgtca
    25681 aacggcaaac agtaccaatt cacctatcac agtcgacaaa ttagttttga ggaggacaag
    25741 ggatgatcag accgacttct tatgagtcat tagcggctct tattgaaaaa gaagataagc
    25801 tggtgttatt ttttacggca gactggtgtc cagactgtca atttatttat cctattatgc
    25861 cagaaattga agcagaactt acagatatga cttttatttg tgttaatcgt gatcagttta
    25921 tagaggtagc acaaaagtgg aatatttttg gtattcctag ttttgtcgtg attgaaaaag
    25981 gtcaggaagt agggcgtctg gttaacaaaa tgagaaagac aaaaactgag attatgcatt
    26041 ttttagctgc ttatcaataa gaaaagagga agaataaatg atttttgcat acaataaaga
    26101 acaagttggc gatgtcttga tggttatctt acaagacacc aaagatatca aacgtcaagt
    26161 agaacgaaaa ggcaaagtag cccgtgtttt tgcagaagaa agcggcaaaa cccttgcttg
    26221 gaatatcttt gaagtgtcaa gcttgattac tattgaaggc aatggacaga tttttttgac
    26281 agacgaggac cttgcaagat taaatgcaga gcttgccaag gaaggatttt cagaaaggct
    26341 tgaaccgact gtgggacctg tttttgtggt tggtcaaatt gttgagatgg tggctcatcc
    26401 agatagcgac catcttaata tttgtcaagt ggctattggt gaagatcaaa cggttcaaat
    26461 cgtagcgggc gcaccaaatg ctgcgcttgg tttaaaaacg attgttgcct taccaggtgc
    26521 tataatgcca aatggtagtc tgattttccc aggaaaattg cgtggtgaag aaagttatgg
    26581 tatgatgtgc tctcctcgtg agttggtctt gccaaatgca ccgcaaaaac gtggcattat
    26641 tgaacttgat gagtcagctg tggtaggaga agcttttgac ccagccaaac attggaaagg
    26701 ttagaaaaac cagctgaaat aagactgtat ttaactaaat gaccagaaaa aaaggattag
    26761 gagcccttaa tccttttttc ttatgttttc aaaaacgttt aaaatgaaac ttattttacc
    26821 acaattttta cgaataataa gataaggagg tcagtatgta taataaagtg atagcaatcg
    26881 gtcgtttggt agctaaacca gaattggtaa aaaccgctac ggataagcat gtagcacgtc
    26941 tctctttagc tgttaatcga agatttaaaa atgcttcggg agagcgagaa gcggatttta
    27001 tttcaattgt tgtttgggga aagttagcag aaactctggt ttcttatgct agcaaaggta
    27061 gtttgatgtc tattgatggc gaacttagga cccgcaagta tgataaagat gggcaagtgc
    27121 attatgtgac agaagttctc tgccaatcat ttcaactgct tgaaagtcgt gctcagcgcg
    27181 ctatgagaga aaataatgtt actaatgatc tagttgattt agtcttagaa gaagatactc
    27241 ttcccttttg atagaggcta atgcttctca tcagggttca gctgattact gaaatatatg
    27301 atgaggtgat atccgagcaa caaaagtgtg actagatact tctgataaaa ataaaaaaaa
    27361 caccttacga gtatgaacaa agtttcaagt gctagatgtt ggaactttgt tcatcatagg
    27421 aatagtaggg tgttttttag tgtattactt ctttttgttg ctagtgttaa ggtttacttg
    27481 cttacaagcg gttatcaggc cactagaact cttataataa atggagctct ttgagtttgg
    27541 tgtcaatcat ttttaagaca gtcgccaaat cttgtgggtt ttgaacgaaa tcaagggaat
    27601 tgccatcaat tttcattttt ggagagacct tgtagtcttc gtaccaggtt gggtattcac
    27661 cgtggacttg atggtaatat tgctcaagac taggattgcc gtcgacctgc tcaaaacttc
    27721 ggccacgttt ttcaatgcgc tcaagcattt tgtcaaaaga cacatcaatg tagatgagaa
    27781 gatcagggcg ttttttaggc atgccttcta gttcttctaa catgttggcg agaagttcct
    27841 gatagatgtc aagttctgtc ttagtgacat tgccattttt gtagttaagt tttaagaaga
    27901 gttcgtcttc aaaaatagag cggtcaagaa tgttgttatc ggcttgataa gcttctttga
    27961 tggacttaaa ccgtttattc aaaaaataaa tttgaagtaa aaatgcgtac tttttagggt
    28021 cttggtagta gaggtctagc acggggttat tatcaacagc ttcataaaaa acgtcagttc
    28081 ctaagtgctc tccaagtgca gcagcaagcg agctcttgcc ggccccaatt gttccagcta
    28141 gtacaatcaa catgcgtctc cttctaatat cattagcgta ctgttttgaa gatggcttca
    28201 acctcagcta gagtctcagc gcgtgaaaca gcaccacgaa ctttggcagc acctgctgtt
    28261 ccgcgaagat agtgtggcgc taagccccga aattcccgaa cagcaatggt ttcacctttg
    28321 aggttaatca ggcgtttgag gtggtctttg gcgatgtcta attttttggc aaagggaaga
    28381 tctggcaatt cttgaccagt ttcaaagaaa tgattgattt gggtaaaaag ataaggattg
    28441 ttcatggctg cgcggccaat catcacggca tctacaccga tttcttcaat cataaatttg
    28501 gcgtcttgca ccgaacgcac gtccccattt ccaataaagg gaatcttagt gatagcctta
    28561 gaaactcggg ctaatgtctc atggtcgcag gttcctgtat acatttgttc acgggtacga
    28621 ccgtgcatgg caagagcaga tacacctgcc gactcagcgg caagggcatt ctcaacggca
    28681 agtgaactat ccgcccaacc tgtacgcatt ttgacagtca gtggaatatc taaaacagac
    28741 gtgacttcct tgacaatgtg gtaaatctta tcagggtcac ggagccactt ggcaccagcc
    28801 tcgtttttga caactttatt aacagggcag cccatattaa tatcaacaat atcggccttg
    28861 gtattggttt gaatgaaatc agctgcacgt ttcaaccctt ctgcgtcacc accaaataat
    28921 tgaatggaca tagggtgctc attctcgtca atatggagca tgtgaagggt cttttcgttg
    28981 ttgtagagca gccctttttc ggaaatcatt tccataacca ccaaaccagc accaaattct
    29041 ttggcgatgg tacgaaaggc agaattggtc acgccagcca taggggcaag tacagtgcgg
    29101 tgggggattt ccacatcacc aatcctaaag gaagaattaa gctttgtcat tgatgagggc
    29161 ctccaaatca ttttcattaa attggtactt ggtaccacaa aattggcaaa caatctcagc
    29221 acccttatct tcgtcaatca tggcctgtaa atctgctttt ggcaaagtca ttagggctgc
    29281 ttcaaaacgt tctctagaac agtcacactg aaaactcaga ggttcttcag aaagacgctt
    29341 gtaaggttca tctccataga tggcctccaa aagggcatcc acatgatttt tggaagctag
    29401 taggtgagaa atggcaggca tttcttgcag gcgtttttca tagcgagcaa tctcttcttc
    29461 agaagctcct ggtagcacct gcaccataaa gccaccagca accttgacct tatcattttc
    29521 atctaaaagc acattaagtc cgattgcaga tggtgtttgc tctgattcgg ttaagtagta
    29581 ggcaaaatcc tcaccaattt ccccagtaat aagaggcgtt gttgaggtgt aagggttacc
    29641 tgtgccataa tcaataatcg tcacaaaatg accattcccc ataaaaggcc caacaaggac
    29701 ttcacctgtt gcggtctttt taatatcgac accagtattt tgaatgtaac ctttcacatg
    29761 tcctttggta tctgccacag agataatgtg tccaaaagaa gaatcaccaa tcactttgac
    29821 ggtgatttta ctatcgcctt tttgattagc cgccaaaatc tggttggcga tcaaggtacg
    29881 gccaagcgca acagtagacg atgacagcgt gttgtgtttt tcttgagcta atgcaaccgt
    29941 ctcagtgcta tcaaggacat aagccctaaa agcccctgat tgtgctattg atttaattat
    30001 tttatccata acttagatta tagcataaag tgtaaaactt gtattgacag gattgcttga
    30061 aaaatcaata cagatagaca gtaaaaaatc ccagagaatg actcgggatt aagttaaggt
    30121 gtggtctaaa gtcgcgcaat gtggtgacat ggtgcttatg ttaattgctt ggttaaatca
    30181 gcttggaatt tttcctcttt aacttgatac atcaattctt ggatagacag aatcgattca
    30241 tcaaaagata tttcagcaac agcaattcct tttgtaagtt catggtgaac aaaaggaatc
    30301 agttgactgt gagtgatgac caaatctggc tttaaatcag gaatttgata aacattatct
    30361 tgcaatagat aataggaatg aaaatcaatg cttttatccg agaaatacct tggaaaagaa
    30421 tccgttagga gatgagcatt gataaaatta ctggctacga aaacaacaac taaaggaggt
    30481 tggatatttc ttagactttg ctcgatatag tgacaaaaaa gatgaaaatg cttatggttc
    30541 aagtcacgct taccaggaag tttggccatc cactcttcga caattaactt taaggacgta
    30601 tagagttttt ggtttccttt atagtacgga gaaacgaata agttggtctc aggaataaaa
    30661 tgttgcagat taaacaagaa tgattttgaa aaaaacataa gagcttttac taaactagcc
    30721 ttttgctctt ttaggttagg taaaagagtg atgataggat ttaaaagcag gcgaaaagta
    30781 tcattttctt caaaaagttg acaacattgt ctgatatgct caggtgtcca ttgtaagctc
    30841 gcaaaagaat tattagcggt gatataaatt aaatagaggt agtccaaatc tcctgctgaa
    30901 aagtttagtt ggcagtaagt ttcgataata tcatggctac tttttttcaa agaatcatag
    30961 acaaaaagtt tttttaattg ttgaaaaatt ctggtttggg gaatagttac cgaaaattga
    31021 tgccgcttcc acgataaagc caataaaatg tcatagaaag aaaacgattc cgataaccaa
    31081 ggagaggttt taaggtgggt ggaactatgg gataaaaagc tatgaatagt gtttttgtct
    31141 tgctgcgtca agtcataaac tttaatgcca aacttactat atagcagagc gatgaggtaa
    31201 cggatgcgat attcctcacc gacaatcttg ttcttagaga gttttaattc aaagtttctt
    31261 aataaaggaa tcaatgcttc gcgcatccga taagctgagg agtttgataa aaaatgactt
    31321 cttgcaaaat ccgtaagggg acgagagtgg gaaccatttt ttattaaaaa cgctagtaat
    31381 tgtaagacat tagatgatgc atagagttgg taaagataag tttctttaaa aggatgtgta
    31441 aattggcaag atatcatcct tttttggatg gtcatagaca gactaccagg gaaaaaggca
    31501 ttcagttcct cacaataatg gtttagttgt aaaaaggtta agccagtttt ttctgctacc
    31561 tcagttattg gcaaataaga tgtcttaaaa aacaagataa ttaactgaca ttttgattcg
    31621 attgatgatt ccaagtattt ttctatcaag gaaagggacc tctcttccta aacttagaaa
    31681 gccaaataag tctttgataa gtgtattctc ctatttcaat tctatctaag ctaaaaatag
    31741 aaatcaaatc taatggtttt tggtgaaaag tcgaaacctt ttgaaatagc tttaaagcaa
    31801 tattttctca aaaaatcatt ttcaaaaac
//
LOCUS       DATWVB010000017        28747 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.017, whole genome shotgun sequence.
ACCESSION   DATWVB010000017 DATWVB010000000
VERSION     DATWVB010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28747
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.017"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1141
                     /locus_tag="VCX65_000941"
     CDS             <1..1141
                     /locus_tag="VCX65_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEP5053408.1"
                     /translation="FVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNRPIGTAYIS
                     KQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQEGDGFGGV
                     TIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDTETAHLYGE
                     LAQETFSILENGIAYQVFLNEGLMTGVFLDQHDVRRALVDGLAMGKSLLNLFSYTAAF
                     SVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYFKYAKRKKL
                     IFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAANMTVSQFK
                     KQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            1138..1824
                     /locus_tag="VCX65_000942"
     CDS             1138..1824
                     /locus_tag="VCX65_000942"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEP5053409.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            1918..3084
                     /gene="aroC"
                     /locus_tag="VCX65_000943"
     CDS             1918..3084
                     /gene="aroC"
                     /locus_tag="VCX65_000943"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEP5053410.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            3145..3486
                     /locus_tag="VCX65_000944"
     CDS             3145..3486
                     /locus_tag="VCX65_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEP5053411.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASASELFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            3708..5060
                     /gene="gorA"
                     /locus_tag="VCX65_000945"
     CDS             3708..5060
                     /gene="gorA"
                     /locus_tag="VCX65_000945"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEP5053412.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKDKAFDFKQLKANRQAYIDRIHASYERG
                     FEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKAIVDVLVEEM
                     AVGGPCLHPHSEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFGLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(5148..6416)
                     /locus_tag="VCX65_000946"
     CDS             complement(5148..6416)
                     /locus_tag="VCX65_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEP5053413.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(6446..6886)
                     /locus_tag="VCX65_000947"
     CDS             complement(6446..6886)
                     /locus_tag="VCX65_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053414.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITITRALQPVPDKTSNDTPKESSNTIVKIIEKESSQGNQNHTGTSETTDDNKTTLP
                     SSSTTPSHNETTPTAPETPSATEGTQLPNATGAEDANTGLPTNS"
     gene            7121..8263
                     /locus_tag="VCX65_000948"
     CDS             7121..8263
                     /locus_tag="VCX65_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP5053415.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKTAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKALS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            8275..9489
                     /gene="thiI"
                     /locus_tag="VCX65_000949"
     CDS             8275..9489
                     /gene="thiI"
                     /locus_tag="VCX65_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEP5053416.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAIAVR
                     SDRDRTHVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            9527..10819
                     /locus_tag="VCX65_000950"
     CDS             9527..10819
                     /locus_tag="VCX65_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEP5053417.1"
                     /translation="MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTM
                     ATVVALIVALLLFGLIYDLLGVQKNKLAAQKSAQPKVKTARVVANGDILIHDILYMSA
                     RKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKN
                     TGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIKI
                     AILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQMGTEYA
                     LEPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRL
                     ETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTM
                     VLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW"
     misc_feature    10924..10998
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            11033..11347
                     /gene="rplU"
                     /locus_tag="VCX65_000951"
     CDS             11033..11347
                     /gene="rplU"
                     /locus_tag="VCX65_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEP5053418.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            11359..11685
                     /locus_tag="VCX65_000952"
     CDS             11359..11685
                     /locus_tag="VCX65_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEP5053419.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            11713..12006
                     /gene="rpmA"
                     /locus_tag="VCX65_000953"
     CDS             11713..12006
                     /gene="rpmA"
                     /locus_tag="VCX65_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEP5053420.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            12364..13278
                     /locus_tag="VCX65_000954"
     CDS             12364..13278
                     /locus_tag="VCX65_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP5053421.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLSDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            13275..13733
                     /locus_tag="VCX65_000955"
     CDS             13275..13733
                     /locus_tag="VCX65_000955"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEP5053422.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN"
     gene            13723..14613
                     /locus_tag="VCX65_000956"
     CDS             13723..14613
                     /locus_tag="VCX65_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEP5053423.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDTLAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
     gene            15008..15529
                     /gene="pyrR"
                     /locus_tag="VCX65_000957"
     CDS             15008..15529
                     /gene="pyrR"
                     /locus_tag="VCX65_000957"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEP5053424.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDIKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
     gene            15545..16804
                     /locus_tag="VCX65_000958"
     CDS             15545..16804
                     /locus_tag="VCX65_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEP5053425.1"
                     /translation="MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKVIGNDWIDKILPPILVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPLLLGLLVGYVVALLVGVLTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            16865..17800
                     /locus_tag="VCX65_000959"
     CDS             16865..17800
                     /locus_tag="VCX65_000959"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEP5053426.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            17844..18926
                     /gene="carA"
                     /locus_tag="VCX65_000960"
     CDS             17844..18926
                     /gene="carA"
                     /locus_tag="VCX65_000960"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEP5053427.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            19172..22348
                     /gene="carB"
                     /locus_tag="VCX65_000961"
     CDS             19172..22348
                     /gene="carB"
                     /locus_tag="VCX65_000961"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEP5053428.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPTLDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQDLQMHVEHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            22555..23826
                     /locus_tag="VCX65_000962"
     CDS             22555..23826
                     /locus_tag="VCX65_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEP5053429.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNTLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGAAYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            23826..24536
                     /locus_tag="VCX65_000963"
     CDS             23826..24536
                     /locus_tag="VCX65_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053430.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            24548..25768
                     /locus_tag="VCX65_000964"
     CDS             24548..25768
                     /locus_tag="VCX65_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053431.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGEGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            26022..27755
                     /locus_tag="VCX65_000965"
     CDS             26022..27755
                     /locus_tag="VCX65_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEP5053432.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHVLLWMK
                     LFAINGLTLVVVSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTSHSKTVIAHR
                     GLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIRNL
                     TLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLETY
                     HRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFSYR
                     SYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIKDLKQDNSYF
                     SRLVRIISSLY"
     gene            27882..28154
                     /gene="rpsP"
                     /locus_tag="VCX65_000966"
     CDS             27882..28154
                     /gene="rpsP"
                     /locus_tag="VCX65_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEP5053433.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            28164..28403
                     /locus_tag="VCX65_000967"
     CDS             28164..28403
                     /locus_tag="VCX65_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEP5053434.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
BASE COUNT         9023 a         4790 c         6063 g         8871 t
ORIGIN      
        1 ttttgtcgaa aagaagctga cagcaggggt acaattatta gatgaaaaag atttttctaa
       61 tataaaggaa aaaaatcagt tggttcaact ggtgaccaag tccaatcgtc ccattggaac
      121 agcatatatc tctaagcaaa ataaaggaat tggttggtat ctaggaccag aaaaaatcga
      181 cttgtctatc tcttattttg ttagtctatt ttcagttgct aaggccaaaa gacaagattt
      241 tgctcaatcg gacgagacca atgcttatcg cctttttaat caagaaggag acggttttgg
      301 tggagtaaca attgatcttt ataaagattt tgcagtcttt tcatggtaca atgcctttgt
      361 ctatgacaaa aaagaaatga ttatggaggc ttttcaacag gtttttcctg aagtcaaagg
      421 agcttatgaa aagtgtcgct ttaaaggtcc agatactgaa actgctcatc tgtatggtga
      481 gctggcacaa gaaacctttt cgattttaga aaatggcata gcctatcaag tcttcttgaa
      541 tgagggctta atgacaggtg tttttctaga ccagcatgat gttagaagag cactagtaga
      601 tggtttagct atgggcaagt cccttcttaa cctattttcc tatacggctg ccttttctgt
      661 agcagctgct atgggtggtg ctatcgagac cacttctgtg gacttggcta aacgatcgag
      721 agaattatca ctagctcatt ttgagcataa ccagttaaac ttagcctcac atcattttgt
      781 ggtgatggat gtttttgaat acttcaaata tgccaaacgg aaaaaattaa tctttgatgt
      841 gattgtgatt gacccaccaa gctttgctag aaataaaaaa caaactttct ctgtgagcag
      901 ggactaccac aaattaatca cagaggcctt ggacatattg agtcctaagg gaactattat
      961 agcttcaaca aatgctgcta atatgactgt tagccagttc aaaaagcaaa ttatcaaagg
     1021 atttggaagt cgtcgtcctg agtctatgac tctccagcag cttccgagtg actttactat
     1081 caataaagca gatgaaagaa gtaactattt aaaggtattt actataaagg tacgagaatg
     1141 agaattgtag caccagtcat gccaagacat tttgacgagg ctcaagccat tgatatttct
     1201 aaatatgaag atgttaattt aattgaatgg cgagcagact ttcttcctaa ggatgagatt
     1261 gtcgcagtag caccagctat ttttgaaaaa tttgccggaa aagaaattat ctttaccctt
     1321 cggaccgttc aagaaggggg gaatattacc ctttcaagtc aggagtatgt tgatattatc
     1381 aaagaaatca atgctattta taatccagac tatattgact ttgagtattt tacgcacaag
     1441 tcagtatttc aagaaatgct tgattttcca aatcttattt tgtcttatca caactttgaa
     1501 gagactcctg aaaatttaat ggaagctttt tcagaaatga ccaagttggc accgcgtgtg
     1561 gttaaaattg ctgtgatgcc ccagagtgaa caagatgttc tagatttgat gaactatacc
     1621 agaggcttta agacgctcaa tcctgagcaa gaatttgcaa ctatatctat ggggaaatta
     1681 ggaagattgt ctcgttttgc gggagatgtc attggctctt cctggacata cgtttcatta
     1741 gatcatgtta gcggtccagg tcaagtgact ctcaatgata tgaaacgtat tattgaggtc
     1801 ttagaaatgg atatctctaa ctagtgaatg gtctaaaaat attatttcta caatagttaa
     1861 gaaatgatgt ttttagatta atgtttttaa aataagtgga accaaaaagg agaaaaattg
     1921 cgttatttaa cagcaggaga atctcatggg ccatccttaa cagctattat tgaaggtata
     1981 ccagcaggat taactcttca tccagcggat attgatcacg aattacagcg acgtcaagga
     2041 ggttatggcc gtggtgccag aatgtctatt gagactgatc gggttcaaat atcctcagga
     2101 gttcgtcatg gcaaaacaac aggggccccc attaccttaa cggtaattaa taaggaccac
     2161 caaaaatggc tagatgtcat ggctgtagga gacattgaag agactctcaa gttaaagcgt
     2221 cgtgttaagc atcctagacc aggacatgcg gatttggtag gaggtattaa atatcatttt
     2281 aacgatttaa gagatgcttt agagcgttcc tcggctagag aaacaacgat gagagtggct
     2341 gtaggcgctg ttgctaaacg tatcttagct gaacttggaa ttgatatgtt acatcatatc
     2401 ttaatatttg gtggtataac gatcacaata ccttctaagc tctcttttag agagttgcaa
     2461 gaaagggctc tccattcaga gttatctatt gttaatccaa agcaagaaga agaaattaaa
     2521 acgtatattg ataagataaa aaaagaaggg gatactattg gtggtattat cgaaacgata
     2581 gttcaagggg tgccagcagg tcttggatct tatgtccaat gggataaaaa attagatgcc
     2641 aagctggctc aagcagttct ttccattaat gcttttaaag gggtggaatt tggagttggg
     2701 tttgatatgg gattccaaaa gggctctcag gtaatggatg aaatcacctg gacacctacc
     2761 caaggctatg gtcgtcaaac aaaccactta ggtggctttg aaggtggcat gaccacagga
     2821 caacctcttg ttgttaaagg ggttatgaag cccattccta ctttgtataa accactcatg
     2881 tcggtagata ttgatagtca tgaaccttat aaagcaacgg tggaacgctc tgatccgacg
     2941 gccttaccag ctgcaggggt tatcatggaa aatgtggtgg cgacggtgct tgccaaagag
     3001 attttagaga ctttttcttc tactaccatg tctgaattgc aaaaagcttt ttcggactat
     3061 cgtgcctacg tcaagcaatt ttagatagcg agatactggc ttttatggta tcatacaggt
     3121 attaatgaac aaaaggagac tgtcatgtca caagaaattt atgactatgc taatcaactt
     3181 gaaagagcag ttcgtgctct gccagaatac caaaaagtgt tagaagtaaa agaggccatt
     3241 caagcagacg ctagtgctag cgaactgttt gatgagtttg tcgctatgca agaaaaaatc
     3301 caagggatga tgcaatcagg ccaaatgcca acggctgaag aacaaacaag cattcaggaa
     3361 cttagccaaa agattgaagc taatgaccag ctaaaagctt attttgaagc gcagcaggcc
     3421 ttatctgttt acatgagtga tattgagcgt attgtatttg ctccgttgaa agatttagtc
     3481 aagtaagcca attaagatag gaaaaaaaac agattgctgg cagctcgtca ggatctgttt
     3541 tttagtgttt attttctttg tatcagaaag ttgagcctct ttcttatttg tgatatagtc
     3601 aaataaattg accaaaatag caggccagta gtggctttaa tgaaggcaag ttgtctgcta
     3661 actggctatg ctaaaacatc agtattagaa agtaaaaggt tataaaaatg gttattcctt
     3721 atgattatat tgttattggt ggagggagtg caggtattgc ttctgcgaac agggcagcca
     3781 tgcatggggc caaagtattg ttagctgaag gtaaagagat tgggggaacc tgtgttaacc
     3841 taggctgcgt tcctaaaaaa gtcatgtggt atggcgctca agtagcagat attttaggga
     3901 cttacgctaa ggattatgga tttgacttta aagacaaagc atttgatttt aaacaattga
     3961 aagcaaatcg tcaagcttat attgatcgga ttcatgcttc ttatgagcga ggctttgagc
     4021 agaatggtgt tgaccgtatt tatgattatg ctgttttcaa agatgctcat acggtagaaa
     4081 ttgcagggca gctttatacc gcaccgcata ttttgattgc cacaggagga catcctgttt
     4141 ttccagatat tgagggggca caatacggta tcagctcgga cggctttttt gccttagatg
     4201 aggtaccaaa acgtacggct gtggttgggg caggctatat tgctgtggaa cttgccggtg
     4261 ttttgcatgc tttggggtcg aagacggatt tgtttatccg tcacgatcga cctttaagaa
     4321 gttttgacaa agccattgtg gatgttttag ttgaggaaat ggcagttggt ggtccttgct
     4381 tacaccctca ttcagaagtg gcaaaggttg tcaaaaatac tgatgagtcc ttgacccttt
     4441 acctcaaaga tggccaagaa gttgaggttg accagctcat ttgggctatc ggtcgcaagc
     4501 ctaatctaga aggttttggt cttgacaaaa ctggagtgac gttaaatgat aaaggttata
     4561 ttgagacaga tgcctatgaa aacacgtctg tcaaaggtat ttatgccgtg ggagatgtta
     4621 atgggaaact ggctttaact ccagttgctg tggcagctgg acgtcgccta tcagagcgtc
     4681 ttttcaatgg caaaacagac gagaaattgg actaccaaaa cgttgctact gtgattttta
     4741 gtcaccctgt tattggctct gttggcttgt cagaagaagc agcagtcaaa cagtatgggc
     4801 aagaagcagt taaaacatat caatcacgtt ttacgtctat gtttactgct atcactaacc
     4861 atcgccaacc ttgtctgatg aagttggtaa cagtcggaga taccgaaaaa atagttggtc
     4921 ttcacggaat cggctatggg gttgatgaaa tgattcaggg ctttgcagta gccatcaaaa
     4981 tgggagcaac caaggcggat tttgataaca ccgttgctat tcacccaact ggctcagaag
     5041 aatttgtcac catgcgctaa aaaatgtagc ctaaggcaat aaaaaatgat gttaacagtt
     5101 tttgaggaaa gtcttctaaa ctgctagcat cgttttttgt taggtgatta ggggaatatg
     5161 tttttaaaga tatttgcgtt gctcagacaa tattgcctta cctcggagat aaaataaagt
     5221 gaccctgtaa caacaaagag ttcatcagat gttacggaac cttgtaacca gtctctgtaa
     5281 tcttttacct gtgggtattt atcaggataa tcctctaaaa gatttgcttc agggaaatca
     5341 aaagtcgtga cagatacttc aaaagtatct agttgagcca gcaagtcggc taaaggctta
     5401 cgtttgagac ctgcaaagag aatatgaata ggacgtttgg gaaattcttc ttgcagtaga
     5461 gactttaatt tagcaatgga atctggattg tgagcgccgt ctaatagaag attaggttga
     5521 ataaattcgg accggccagg ccaagttgtt gcctcaattc ctttttgaat cgtttttgga
     5581 gatattttag gaaaggattt tctaagtaat tgagctgtca taatggctaa acaggcattc
     5641 gctttttgat gttgacctaa tagtttgaga cggagtttgg ttaaattcaa gttatcgtgt
     5701 tgaaaggaaa acgtcttttc tgaaggattg agcaaaaaat cttttcctaa ttgatataag
     5761 cgtgaaccgg ctttttgggt aacttgttga aagacttgac tagcctcctg ctcaagttga
     5821 ccgataataa cgggttcttt agctttgata acttctgctt tttggtgagc aatttctgct
     5881 aggctataac ctaaacgttc ttggtgatca aaactaatag aagggcatac gacggccaga
     5941 gcatgaaaaa cattggttgc gtcggttttc ccaccaatcc ctgcctcaat aatggcaata
     6001 tcaacaggtt taagattggc aaagtagcaa aacattatga gagtcactaa ctcaaactcg
     6061 gtaggtctat cccaatttgt ttcaagggac attttagtga gaatgggtct aatcacgctc
     6121 acacattgcg ccaattctag gtctgaaatg ggctggccat taaggcaaat ccgatcgtga
     6181 aaagagataa taaaaggaga tgtaaaggtt ccgacctgat aaccagaagt tgacaggata
     6241 tgctgtaagt aggctgtcac agagcccttg ccgttagttc caacaacgtg aatagcaggg
     6301 aatttgtctt gtggccggcc taatgcctca agtaaccaag ccattctggc caaatcggtc
     6361 ttgcgaccat tagccttaaa ggtatgaatc caggaaatgc tatcataggt agtcattact
     6421 atttcttgtc cttctaacaa tgcttttaag agttcgtagg gagaccagta ttagcatcct
     6481 cagctccagt tgcattagga agttgcgtcc cttcagtggc tgatggtgtc tcaggagctg
     6541 taggagttgt ctcgttgtga gaaggtgtgg tagaagatga cggaagagtt gtcttattat
     6601 catctgtggt ttctgaagta cctgtatggt tttgattacc ctgagaagac tctttttcaa
     6661 taatcttgac aatggtatta ctcgattctt tgggtgtatc attagaggtc ttatctggta
     6721 caggctgcag tgctcttgta atggtaatgg ttgccacaat gatactcaaa atactaccaa
     6781 taagtgcaat ggatttttgg aaagctgtaa aacctgtttt aatatgctcg gtagggacac
     6841 ctcctgattt acgaggtttt tgttgacggg aataacgtga tgacatattt ttctccttta
     6901 aaatcatcgt aatgccaaga ttaaggagga ggaaatagaa gtcctagctc ctctttaaca
     6961 cttcatctat cagtataatc tagaaaaaaa gtgaagtcaa cggtttacct tatgtctagg
     7021 acaaggaagt cctttgggct tattgtaata cgaatattct tgatttcatt ttagctattt
     7081 tgtgatagaa taaagtattg agtaaaaatg aaggtgacac atgatttatt ttgataatgc
     7141 agccacaacc ataccttatg gagaggctct taaaacttac caagaagtag caacaaaaat
     7201 atatggcaat ccctcaagtc tgcaccaatt agggacaaat gcgtctcgca ttttagaagc
     7261 ttcccgtaaa cagattgctg gtttgttggg tgttaagtca gaagaaatct tttttacgtc
     7321 tggtgggact gaaagtgcta attgggctat taagggaatt gcttttgaaa aaactgcttt
     7381 tggcaaacat attattatct cagccattga acaccctgcc gtgagtgaaa gtgtcaaatg
     7441 gcttctcaca caaggattcg aagtttctta tgctccagtg acaacacagg gagttgttga
     7501 tgtgaatgct ttagctgagc tgattagacc agacaccatc ttaatctcga ttatggctgt
     7561 taataatgaa atgggagcta tccaaccgat tagagccatt tcaaacctat tggctaacca
     7621 accaacgatc acctttcacg ttgatgctgt tcaagccatt ggtaaaatac cactctgtga
     7681 ttatatgact aatcgtgtgg atttggcttc tttttcaggg cacaaatttc atagtgttcg
     7741 tggtgttggc ttcctttata aaaaagcagg caagcgactc aatcctctct tgtcaggcgg
     7801 cggccaagag caggagttac gttcaaccac tgaaaatgtt gcaggaattg ctagcatggc
     7861 caaagcatta agaatagtca ctgaaaaaca agtgagcgtc ttacctaaac taacagcgat
     7921 gcgagatgtg atttacaaag ctttgtccgc ttacccagat gtgacagtat tttcagctca
     7981 agaaggcttt gcgcccaata ttttgacctt tgggattaga ggggttcgag gagaagttat
     8041 tgtccacgcc tttgaaaaat atgagattta tatttcgacc acaagtgcat gttcgtccaa
     8101 agcaggtaag ccagcaggaa gcctagtggc tatggggatt cctgtaaaaa ctgcccagac
     8161 agccgttcgt attagtctag acgatgacaa cgatatggga caagtagagc agtttttgac
     8221 catattcaaa cagatttatg ataaaacaca gaaagttagg taagattagg taagatggac
     8281 tattcagaaa ttatggttcg ccatggtgaa ctgtcaacta aagggaagaa tcgcatgcga
     8341 ttcattaaca aacttaaaaa caatattcaa gacgtactgg ctcctttccc agccattgct
     8401 gtccgttcag atcgtgatag gacccatgtg tctctaaatg gcacagatta tcagcctatt
     8461 gtagaagctt taaagctggt gtttggtgtt caagctctat ctcctgttta taaacttgaa
     8521 aaaagtgtcc ctcttttggt aacagctgtt caagatatca tgacttctct ttatcgtgat
     8581 ggactgacgt ttaagattgc cactaagcgt agtgatcacg cgtttgaatt ggatagtcgt
     8641 gagcttaaca gtcttcttgg tggagctgtt tttgaggttt taccaaatat ccaagcccag
     8701 atgaaacatc ccgatgtgac tctcaaagtc gaaattcgtg atgaagcagc ttacatttct
     8761 tatgaagaga ttaagggagc aggcgggtta ccagtaggaa cgtcagggaa agggatgctg
     8821 atgttatcgg gcggtattga ttcaccagta gctgggtatt tagcccttaa acgtggcctc
     8881 gatattgaag ttgttcattt tgctagccct ccgtacacca gtccaggtgc cttggctaaa
     8941 gcccaagacc ttactcgtcg gttaactcgt tttggtggaa atatccaatt tatcgaggtt
     9001 ccttttacag aaattcaaga agaaattaaa aataaggcac cagaggctta ccttatgaca
     9061 ttaacccgcc gctttatgat gcgcatcaca gatgccattc gtgagcaacg taagggtctt
     9121 gttattgtta acggtgagag cctaggtcag gttgctagtc aaacccttga aagcatgcag
     9181 gccattaatg cggtaacatc aaccccaatt attagaccag tcgtgacaat ggataaactt
     9241 gaaattatcg agatggctca ggcgattgat acttttgaca tttctattca accgttcgaa
     9301 gattgctgta ctatttttgc accagaccgt cctaaaacca accctaaact aggtaatgct
     9361 gaaaaatatg aagaacgctt tgatattgat ggtcttgtcc agcgtgctgt gtcaggaatt
     9421 gttgtcacag aaatcacacc tgaaatcgtc aatgatgagg ttgaaaatct cattgatgct
     9481 ttactttaaa agaaaagatc aagtgtaaat cttttagtag tcagtaatga tactattgaa
     9541 aagcctctat aagggctttt ttgctgcaat gaaggaggaa aattttgagg caagatgtta
     9601 taatagagaa aaaggagggt gtgtcttgat taaaactatg caatacaaaa aaacgatggc
     9661 aacagttgtt gctcttatcg tcgcactttt gctatttggc ttgatttatg atttacttgg
     9721 ggttcaaaaa aataagctag cagctcaaaa atctgctcag ccaaaggtca aaacagcgcg
     9781 tgttgtagct aatggcgaca ttttaattca tgatattctc tacatgagtg ctagaaaagc
     9841 tgacgatacc tatgatttca ctccttattt tgaatatgtt aaggactgga ttagcggtgc
     9901 tgacttagct attggagatt atgaagggac cattagccca gattatccct tagcaggcta
     9961 tcccttattc aatgctccag aagagattgc aggtgctctg aaaaatactg gctatgatgt
    10021 agtcgattta gcccataatc atatcttaga ttcccaatta gacggtgccc ttaacactaa
    10081 aaaggttttt catcaattag gtatagacag tattggcatc tatgacaagg atcgttcaaa
    10141 agaatccttc ttaattaaaa atgtcaatgg tatcaaaatt gcaattttag gttattctta
    10201 tggttataac ggcatggagg ccacacttag ccaagaagac tatgagaaac acatgtctga
    10261 tttagatgaa gctaagataa aaaaagaact tcagctagct gaaaaaaagg ctgacgtgac
    10321 cattgtcatg ccacaaatgg gaacagaata tgccttagaa ccgacagcag agcaaaaaga
    10381 actttaccac aaaatgattg attggggagc tgacgtcgtc ctaggaggcc atccgcatgt
    10441 tattgaacct tcagagacag ttataaaagg taggcaaaag aaattcatta tttactctat
    10501 gggaaatttt atttcaaatc agcggcttga aaccgtagat gatatctgga ctgagcgtgg
    10561 cctattgatg gaccttactt ttgagaaaaa agataacaaa acaaaaatta aaacagttga
    10621 ggcccatcca accatggttt tagccaaagg taaaggcatt gtgggtaaag aaggttttga
    10681 actatacaat tatcgaacaa tggttttaga agattttatc aaaggtggaa aataccacga
    10741 caagattgat gaggaaacca aagcaaaagt agcacttgct tatcaggaaa ttaatgattt
    10801 agttaacctg aaatggtaat gtttggtggt ttagcatcta acgataaaaa atagagatta
    10861 aacttaattt ttccttgata aaaagcagtt atggtgctaa aatagtaacg ttgactaaat
    10921 gcacatcctg tgcaaccgcg cgaaaatcgt tgtcaagtag accaagtctc acgattccag
    10981 gcgagtcttc acagagggaa acctcaaaca aaaattttat aggaggtgca tcatgagcac
    11041 atacgcaatc atcaaaactg gtggaaaaca agttaaagtt gaagtaggtc aagcaatcta
    11101 cgttgagaaa attgacgctg aagctggcgc agaagtcact tttaacgaag ttgttcttgt
    11161 aggtggtgac aaaactgtag ttggtactcc agttgttgaa ggagctactg tcgttggaac
    11221 tgttgaaaaa caaggaaaac aaaagaaagt tgtaacattc aaatacaaac ctaaaaaagg
    11281 tagccaccgt aaacaaggtc atcgtcaacc ttacactaaa gttgtcatca acgcaatcaa
    11341 cgcttaattt actagcttat gattaaagca atttttactc gccaaaaaaa tggtcaactg
    11401 agcagtgtta cactgacagg tcatgctggt agtggtaaac atggctttga tattgtttgt
    11461 gcctctgtta gtactctagc cattaacttt gttaattctc ttgaggtgtt agcagattgc
    11521 caagcattag tagatcttaa tgatgttgaa ggtgggtata tggctattac aataccacca
    11581 catgacaaca aggaggaagt tcaattatta tttgaatctt ttcttctagg aatgactagt
    11641 ttggcgaagg attcttcgaa atttgtcaac actcaggtca tctaaattta atttaagaga
    11701 ggaaacaaca ttatgttaaa aatgaatctt gctaacttgc aacttttcgc ccacaaaaaa
    11761 ggtggaggtt ctacatcaaa cggacgtgac tcacaagcta aacgccttgg tgctaaagct
    11821 gctgacggtc aaactgtttc aggtggatca atcctttacc gtcaacgtgg aactcatatc
    11881 tacccaggtg taaacgtagg ccgtggtgga gatgacacac tttttgctaa agttgaaggt
    11941 gttgtacgtt tcgaacgtaa aggacgtgat aaaaaacaag tttctgttta cccagtagct
    12001 aaataattgt ttaacatcgc attatataag gctttccagg tgtctggaaa gccgattttt
    12061 ttattttggt actcatgttg ctatccatat tttaaaaatc aatgtaggaa gagagcttgt
    12121 cagcagtttt atcttttgag gatttagtaa catgagcgta gatgttcatg gtagtttgga
    12181 tagtttcatg accaagtgta ttggattttc attgtttgtt tctatcctac taaagattgt
    12241 agttgcttat ttagagcaat agttctaatt gtaaaaagtc agcataataa aacaatgtca
    12301 taagatgttg ttataacggg ctttatggta taattaagga tactcatttt aggaaggaaa
    12361 gcaatgaata ttcaacaatt acgctatgtg gtagccatcg ctaataatgg aacttttcga
    12421 gaagctgcct ctaaattgtt tgtcagtcag cctagcttat cagtttctat caaagattta
    12481 gaggcggaat tagggtttca aatttttaat cggactactt caggaacagt cttgacaagt
    12541 caaggactag ttttttatga gaaagcttta gaagtagtca aatcttttga ttcttttgaa
    12601 aaaacctttt ctcaagctga tctggatcaa aatgaatttt ctattgctag ccaacattat
    12661 gactttttgc cacctcttat tacagctttt tcgcaacaat acgatggtca tcgtgtcttt
    12721 cgtatctttg aatcaacaac tattcaaatt ttagatgagg ttgctcaagg aaacagtgaa
    12781 attggtatta tttacttgaa tgtagacaat caaaaaggtc tctttcagcg gatggataag
    12841 ctgggcttgg aatatgtttc tctaattcct ttcactactc atatttatct ttcaaaaacg
    12901 catccattgg ctaatcgcga agcgctttat ttgagcgata ttcaaggatt acctgcggta
    12961 aggtttaccc aagaaaggga cgagtatttg tattattctg aaaattttgt ggatactagt
    13021 gaatgccctc gtatttataa tgtgtcagat agggcaacct tgaacggtat tttagagaga
    13081 accaatgcct ttgcgacagg atcaggtttt ctcgatcatc ggagtgttaa tgggattaaa
    13141 gtgatacctc tagctgatca tattgacaat caaatgattt atgtcaaacg aaaagataaa
    13201 aacctttctg ttgctggggc cacttttgtg actattttaa aagactattt tgataaaaga
    13261 aggaaggcct taacatgaaa aaacgattgt ttgtgcttag cttgatcctc cttgtagctt
    13321 tggatcaact tagtaaattt tggattgttt ctcatatagc gcttggagaa gtgaaaccct
    13381 ttatcccagg tatcgtcagc ttgacttact tgcaaaacaa tggggccgcc ttttccatat
    13441 tgcaggacca gcaatggttc tttgttgtca taacggtttt agttatcggt tatgctattt
    13501 attaccttgc tactcatccc catttaaata tctggaaaca attagctctc ttgcttatta
    13561 tttctggtgg aatcgggaat tttattgatc gtttgcgttt agcttacgtg attgatatgg
    13621 ttcatttaga ctttgtggat tttgccattt ttaatgtggc agattcatac cttaccgttg
    13681 gtgtcatatt attagtgata tgtttatgga aagaagagga ttatggaaat taatgtgata
    13741 acatcggggc aacgcttgga taaggcacta gctgatttaa gtcccctgtc acgtggtcaa
    13801 gccaatgacc aaattaagca aggccttgtt ttagttaatg gtcagcaaaa aaaggctaaa
    13861 tatacggttc aagcaggaga tgtgatttgt tttgaactcc ctaaagaaga agtcttagag
    13921 taccaagctc agaatattcc cttggacatt atctatgaag atgatactct cgccattatt
    13981 aacaagccac agggaatggt agttcaccct tcggcgggac acccttcagg aacaatggtt
    14041 aatgccttga tgtatcatat caaggatttg tcctcaatca atggtgtggt tcgtccagga
    14101 attgttcatc ggattgataa ggacacctca ggtctcttaa tggtagctaa aacagatgca
    14161 gctcatcaag ccttggcaga agaattaaag gctaaaaaat ctctcagaaa atacctcgcc
    14221 attgtccatg gaaacctacc gaatgatcgc gggatgattg aagctcctat aggtcgtagc
    14281 gaaaaggacc gtaaaaaaca ggctgttaca gcaaaaggca aagaagcagt gacacgtttt
    14341 acagtgctag aacgttttgg cgattacagt ctagtggaat tacaactgga aactggtcga
    14401 acgcaccaaa ttcgtgttca tatggcctat attggtcatc ctgttgctgg ggacccttta
    14461 tatggaccac gtaagacact atcaggtcat ggccaatttc ttcatgcaaa aacattggga
    14521 ttaacgcatc ctatgacagg aaaagaaatg atatttactg ttgaagctcc cgaaattttt
    14581 caaaaggtgt taaagctgct aagaaaaaaa taaacagcga ggagtagcca ttatttttag
    14641 tcttatatct ttgtgtaaag tttttaacat tataaaaaat actaaaaagc atttacgata
    14701 agccaggaaa tatgagaagt cttttatgtt attgggatat gcaacatatc tgttagagat
    14761 ctttatttaa actcttaaag aaaagagata ttccaaatag atgctaggta ttgtcttttt
    14821 tacttgtttt tcttttcttt ttttgctata ctgattgaaa taaaatattc ctttaaaaca
    14881 gtcctgtgag gctgtcaagg agacggatta aaaacatgca ctatgatact taattgtgct
    14941 atattttgct gaatctcctt gtttccaagg agatcttttt atttgaattt ttagaggagg
    15001 tttcaacatg aaaactaagg aaattgttga tgacgtgacc atgaaacgcg ccattacccg
    15061 tattacttat gaaattattg aacgtaataa acaattagac aatgtggttt tggcaggcat
    15121 caaaacgaga ggtgtttttc tagctcgtcg cattcaagaa agactgcatc aattagaagg
    15181 gttggattta ccaattggtg agttagacat caagcctttt agagatgaca tgagagttga
    15241 ggaagacaca actctgatgt cagtagatat tacaggcaag gatgtgattt tgattgatga
    15301 tgtgctttat actggtcgta ccatccgcgc ggccatcgat aacttagtga gtttaggtcg
    15361 accagcccgt gttagtctag ctgttttggt ggatcgtggc catcgggaat taccgattcg
    15421 cgcggattac gttgggaaaa atattccaac aagcagtgta gaagaaattg ttgttgaggt
    15481 tgtcgaagtt gatggccgtg atcgtgttag cattattgac ccaacataag aaggaggttt
    15541 tactgtgaaa gatgtcattt atgatgtgga agaagtgcca aaggcaggta tgttagttgg
    15601 tttgtccttt cagcatttat ttgccatgtt tggggcgacg gttcttgttc ctattttagt
    15661 tggaattgac ccgtctgtgg ccctcctatc gagtggttta ggaacacttg cacatttatc
    15721 ggtaaccaaa tttaaaattc cagcctacat gggctcaagt tttgcttata tagcagctat
    15781 gcagttactg atgaagacaa atggtattgg tgctgtagct caaggggcta tgacaggagg
    15841 tctcgtttac ctgattgtag ctttgattgt taaagttatt ggcaatgatt ggattgataa
    15901 gattttacca ccgattttag ttggtccgat tgttatggtc attggtctaa gtctagcttc
    15961 tacagctgtt aatgatgtca tgttaaaaaa tgggaactat aatctgactt atcttgttat
    16021 tgggttagtc accttattat cagttatttt tttcaatatt tatggtaagg gaattgttgc
    16081 tattgtaccg cttttattag ggctattagt tggttatgtt gtagcccttt tagtgggtgt
    16141 tctcaccggt caagaaattg ttgattttac caatgtggct caggccaaat ggtttagtat
    16201 cccatcagtg gaaattcctt tcttaaccta cggggttaaa ttctacccaa gtgccatttt
    16261 aactatggca cccattgcct ttgttacaat gacagaacat tttggacaca ttatggtctt
    16321 aaatagtttg acaaaaagag attatttcaa ggatccagga cttgaaaaga ctttaactgg
    16381 tgatggtttt gcgcaaatca ttgctggctt cttaggggca cctccggtca cttcttatgg
    16441 tgaaaacatc ggtgtaatgg ctctgaataa aatattctcg gtctatgtta ttgcaggtgc
    16501 cgcagtgatt gccgctctcc tcagttttat cggtaaggta tcagccttaa ttcaatctat
    16561 tccaacacca gttattggag gtatatcagt tgccttgttt ggtgtaatag cttctagcgg
    16621 tttgaaaatc ttgattgaat ccaaagttga tatggataat aagaaaaact tattgattgc
    16681 cagtgtcatt ttggtctctg ggattggagg attgatgctt caagtaaatg gtcttcaaat
    16741 ttcaggtgtc gctttctcaa cacttcttgg catcatctta tatcaggtac ttcctgaaaa
    16801 ataggaagaa ttgttgttag accacttaca tagtcatcag tcgttagtga taaaggggat
    16861 aatcatgtca gttgtaaata atcgcgttgc acttaccaat ttagtttcaa tggaagcatt
    16921 aaccaccgaa gaagttttag gtcttatcaa ccgtggttca gaatataagg ctggtaaggt
    16981 tgttatttcg gatcatcaaa aggatcttgt tgccaattta ttctttgaaa actccacccg
    17041 aacccataag tcttttgaag tggctgagaa gaaactcggc ttgacagttc ttgatttcaa
    17101 tgctgatgca agtgcggtta acaagggaga aagtttgtat gatactgtgt taaccatgag
    17161 tgcacttgga acagacatct gtgtgattcg tcacccagaa gatgattatt acaaggaatt
    17221 agtagaaagt ccaactatta cagcttccat tgtcaatgga ggagatggtt ctggacaaca
    17281 cccgagtcaa tgtttacttg acttattaac catctatgaa gaatttggac gctttgaagg
    17341 cttaaagatt gcgatcgctg gtgacttaac tcactctagg gtggcaaagt ccaacatgca
    17401 aatcctcaaa agattaggag cagagcttta tttctatgga cctgaagaat ggtattcaga
    17461 agcctttaat gcttacggca cttatattgc tattgaccag attattaagg aattggatgt
    17521 tcttatgttg ctgcgtgtac agcacgaacg tcatgacggc catcagagtt tttcaaaaga
    17581 aggttaccat caagcgtttg gattgacaca ggaacgttac caacaattaa aagattctgc
    17641 tattattatg catccagctc cagttaatcg ggatgtggaa attgcagata gtttggtgga
    17701 agctcctaaa gcgagaattg tatctcagat ggctaatggt gtctttgttc gcatggctat
    17761 tattgaagcc attttgaatg gtagaaataa aaactcatga tgaaagatta aagcatgttt
    17821 agaaggtagg aaaaggtagg aaaatgacaa aacgattact tattttagaa gacggcacta
    17881 tttttgaagg agaacccttt ggtgctgata ttgatgtgac tggtgaaatt gtctttaata
    17941 caggaatgac aggctaccaa gaatccatca ctgaccaatc ctacaatggg caaattttaa
    18001 cctttaccta tcctttgatt ggaaattatg ggattaatcg agatgactat gagtccattt
    18061 cacccacctg taaaggggtt gttgtgtctg aagtcagtcg gttggcaagt aattggcgca
    18121 agcaaatgac gctagatgcg ttcttgaaaa taaaagggat tccagggatt tcgggaattg
    18181 atacgagagc tttgaccaaa attattcggc aacacggtac catgaaagct acgatggcag
    18241 atgatggaga tagtatccag catttaaaag atcaactgcg tgcaacagtc ttaccgacta
    18301 acaccattga acaagtgtca actaaaacag cttatcctgc accagggatc gggaaaaata
    18361 ttgtattggt tgattttggt ttaaaacatt ctattttaag agaattttct aaaagacaat
    18421 gtaatatcac cgttgtccct ttcaacatca ctgcagaaga agtgctccaa ctaaatccgg
    18481 atggtttgat gctatctaat ggcccaggaa acccagaaga tttgccagag gctttagaca
    18541 tgattcgtgg ggtacaaggt aagattccta tttttggtat ttgtatggga catcaactct
    18601 ttagtctagc aaatggtgcc aagacttgta aaatgacctt tggtcatcgt ggctttaacc
    18661 atgccgttag agaaattgca acgggaagaa ttgattttac cagtcaaaac catggttatg
    18721 ccgttgaacg tagtagtcta cctgatactt taatggttac gcatgaagac attaacgata
    18781 agacggtcga aggagtgaaa catagagatt ttccagcttt ttcagtccaa tttcaccctg
    18841 atgcggctcc aggacctcat gatgccagct acttatttga cgaatttttg gaaatgattg
    18901 attcttggag atgtacgagt aaatagtaaa tcagttgcaa tttcacgact atatcacctc
    18961 ttgttactct atttattaac atttacagtt gatttagtac cctatcaaaa atattattta
    19021 atgttgctct gtgaggcaac aaatagagaa aggaaggcaa ggagaacaca agtaaataat
    19081 ttagtaaaaa gttaggtttt caaagagata aagctcttat tgagaagtgc tgactttacc
    19141 gcttcttgtg gtattcttgg tatcattaat tatgccaaaa cgaaaagata ttcaaaaaat
    19201 catggttatc gggtctggcc cgattattat tggacaagct gctgaatttg attatgcagg
    19261 gactcaggcc tgtttggctc taaaagaaga aggctataag gtcatacttg ttaattcaaa
    19321 tcctgcaacg attatgacag ataaagaaat cgctgataag gtatatattg agcctttgac
    19381 tcttgaattt gttaatcgta tcattcgaaa agaaaggcca gatgccatac tgccaacctt
    19441 aggtggtcaa acgggcctca atatggcaat ggcattatct aaagctggta ttcttgatga
    19501 tttagagatt gaattgttag gtactaagtt atctgcgatt gatcaggcag aagacagaga
    19561 ccttttcaaa caattaatgc aagaactaga ccaacccatt ccagaatcta caattgttaa
    19621 aacagttgat gaagctgtta catttgctag agatatcggt tatccagtca ttgtgcgccc
    19681 agcttttact cttggtggaa ctggtggagg aatatgtagt agtgaagaag aactttgtga
    19741 aattactgaa aacggcctaa agttatcacc ggtcacacag tgtttgattg aacgctcaat
    19801 tgctggcttc aaagaaattg aatacgaagt aatgcgagat agtgctgata acgcgctggt
    19861 tgtttgtaat atggaaaact ttgatcccgt agggattcac acaggagatt ctattgtatt
    19921 tgcaccaaca cagacccttt ctgatattga aaatcaaatg ttacgtgatg ctagtttaaa
    19981 aataattcga gctctgaaaa ttgaaggtgg ctgtaacgtc cagttagcac tagatcctta
    20041 tagtttcaaa tattatgtta ttgaagtaaa tcctagagtg tctcgttcct ctgcccttgc
    20101 ttcaaaagca acaggttatc ccattgccaa attggctgca aagattgctg ttggcctaac
    20161 acttgatgaa atgattaacc ctatcacagg cactacttac gctatgtttg aacctaccct
    20221 tgattacgtt gttgctaaaa ttccgcgttt tccgtttgat aaatttgaac atggtgaacg
    20281 ccaactggga actcaaatga aagcaacagg tgaagtcatg gctattggcc gtaatttgga
    20341 agagtcctta ctaaaagcct gtcgttcttt agaaattggt gtttgccata atgagatgac
    20401 aagtttaagt aacattagtg atgaagagtt agtgactaaa gtgattaaag ctcaagatga
    20461 tcgacttttt tacttgtcag aagcaatacg acgaggttat agtatcgaag aacttgagag
    20521 cttgaccaag attgatttat ttttcttgga taaattactt catattgttg aaatagagca
    20581 agatctacaa atgcatgttg agcatttgga aagcctcaaa aaagcaaagc gttatggatt
    20641 ttcagatcaa aaaattgcag aaatttggca aaaggatgaa agtgatatca gagcgatgag
    20701 acattctcat agcctgtatc ctgtctataa aatggtagat acttgtgcag ctgaatttga
    20761 tgctaaaacc ccttattttt attcaacata tgagttggaa aatgaatctg ttcagtcgaa
    20821 taaagaatca attttagttt taggttcagg ccctattcgt attggtcaag gggttgaatt
    20881 tgactacgca acggttcatt ctgttaaagc catccaaaaa gctggctatg aagccattat
    20941 catgaattca aatccggaga ctgtatctac agatttttcg gtatcagata aattatattt
    21001 tgaaccgtta acctttgaag acgtcatgaa tgtgatagat ttagagcagc ctaagggagt
    21061 aatagttcag tttggaggac aaactgctat taacttagca caagcacttt ctgaggcggg
    21121 tgttacaata ttaggaacac aagtagagga tttggatagg gctgaagaca gagatttatt
    21181 tgaaaaggcg ttgaaagagc ttggaatccc acaaccacaa ggtcaaacgg caactaatga
    21241 agaagaagca ttagaggcag ctaaaaaaat tggttttcca gtcttagtta gaccttctta
    21301 cgtacttggc ggccgggcta tggaaattgt tgaaaacaaa gaagatctta gagaatatat
    21361 aagaacagcg gttaaagcaa gtcctgaaca tcctatctta gtggactctt atattttcgg
    21421 taaggagtgt gaagtggatg ccatttcaga tggaaaatca gtcttaattc ctggtattat
    21481 ggagcacatc gaaagagcag gtgttcattc aggagattca atggcagttt atccgccaca
    21541 gcaattatct aagcaaattc aagaaacaat agctgagtat actaaacgtt tagccattgg
    21601 gttaaattgt attggtatga tgaatgttca atttgttatt aaaaatgaac aagtctatgt
    21661 tattgaagtg aatccacgcg ctagtcgtac cgtgcctttc ttatcaaaag taacaggtat
    21721 tccgatggct cagattgcta ctaagttgat tttaggtcaa acattaaagg atctaggata
    21781 tgaagatggt ctttatcccc aaagtcaact ggtgcatatc aaagcgcctg tgttttcatt
    21841 tacaaagttg gcacaggttg atagtctttt aggtcctgaa atgaaatcaa ctggagaagt
    21901 aatgggttcg gatactagtc ttgaaaaagc actttataaa gcgtttgaag ccaataattc
    21961 tcatttatca gaatttggtc aaattgtctt tactatagca gatgatagta aggcagaagc
    22021 tctaagtcta gcaagacgat ttaaggcgat tggctatcaa attatggcta ctcaaggtac
    22081 agcagcttac tttgctgagc aaggcttaag cgcgtgttta gttggaaaaa ttggtgatgc
    22141 tgccaatgac atcccgacac tcgtgcgaca tggtcacgtt caggcaattg ttaatacagt
    22201 tggaattaaa cgcacagctg ataaagacgg acagatgatt agaagttcag ctattgaaca
    22261 aggagttcct ttatttacag ctttagatac tgcaaaagct atgttaacgg ttttagaaag
    22321 cagatgtttt aacatcgaag cgatataaaa attaaaaaat catttttaag aaaacttaaa
    22381 aatgattttt ttagattata atgacaaaag tttcagtaag ctattaattt gtcatagcat
    22441 ataagtcatt atcttgtggc ttgttttcga ctaagggtta agaatttctt gacaacaata
    22501 taaaaaggtc atatacttgt cttatacaaa tagtacaaaa aggggaggat agaaatgtct
    22561 aaaagaggaa aaattaaaat aacaacgaaa acaaagctta ttacagctag tgttataacg
    22621 ctagtattaa ttataactgg agtagtcttg tggaaacaac aacaaaatac gctaacagct
    22681 gatatcgcta aagaacctta ctctactgtt agtgtaactg aagggagtat tgcttcttcg
    22741 actttactct caggtactgt aaaggcttta tcagaggaat atatttattt cgatgctaat
    22801 aaaggaaatg atgcaactgt tacagttaaa gtaggtgatc aggtaacgca gggccagcaa
    22861 ttagttcaat ataatacaac aacagctcag tcagcttatg atactgctgt taggagtctt
    22921 aacaagattg gccgacaaat taatcatctt aaaacatacg gagttcctgc tgttagtaca
    22981 gaaactaata aagatgaagc taccggtgaa gagacgacaa caacagttca accatcagct
    23041 cagcaaaatg ctaattataa acagcagctg caagatttaa atgatgctta tgcagatgca
    23101 caagcagaag taaataaagc gcagatagcg ttaaatgata cagtagttat cagtagtgtc
    23161 tctggaactg ttgtggaagt aaataatgat attgatcctt cttcaaagaa cagtcaaaca
    23221 cttgttcacg tagcaaccga aggacagctt caggtgaaag gaacattgac agagtatgat
    23281 ttagcaaacg ttaaggttgg tcaatctgta aaaattaagt ctaaagttta ttctaatcaa
    23341 gaatggactg gaaaaatatc atatgtttca aactatccaa ctgagtctaa tgcaggttca
    23401 acaacgccag caggtagcac tggagcggga agttctacag gagctgccta tgattacaag
    23461 attgatatta taagtcctct caaccagctt aaacaaggtt tcactgtttc tgttgaggtt
    23521 gttaatgaag ctaaacaggc cttagttcct ttaacggctg ttattaagaa agataaaaaa
    23581 cactatgttt ggacttatga tgatgctact ggcaaagcca aaaaagtaga ggtgacactt
    23641 ggaaacgcag atgcacaaca acaagaaatt cataaaggag tagctgttgg tgacattgtt
    23701 attgccaatc cagataaaaa tatcaaaccg gataaaaaac tagaaggggt tatttcaata
    23761 ggtaccaaca caaaaccgga aaaagattct caatcaaaga ataaaaaatc aggggtggat
    23821 aaatagtgtc gcatgaaaaa aaacaattaa tgcaattatc aaatattgtg aagagctatc
    23881 aaaatgggga tcaagttctt aaagttttga aaggtattaa tttaacagta tatgagggtg
    23941 aatttttagc tattatgggt ccgtctggct cgggaaaatc aacactaatg aatattattg
    24001 gtttattaga tcggccaaca tccggagatt acacattaca taatactaaa atagaaatcc
    24061 ttaatgatcg tgaattagca aaagtacgaa acgatgaaat cggctttgtc tttcaacaat
    24121 tctttctgtt agctaaatta actgcattac aaaatgttga gttgcctctt atttatgctg
    24181 gtgtaaacgt ctcaaaaaga cgtgaacagg ctaagcaatt tcttgaaaaa gtaggacttg
    24241 gacgacgtat caaacatcta ccgtcagaac tgtcaggagg tcaaaagcaa agggtggcta
    24301 tcgcacgagc tttagtaaat gacccatcta ttattttagc ggatgaacca acaggtgcac
    24361 tagatactaa aacaggtcag caaattatgg aactcttgac agagttaaac aaagaaggta
    24421 aaacaattat tatggttact catgaaccag aaattgctga ttttgcaact cggaaaatta
    24481 ttattcgtga tggtgatatc acaacggata ctacagctag tgttgttatt gactaggagg
    24541 aaaaataatg gaaaattgga aattcgctct tagctcaatt tgggggcata agatgcgctc
    24601 aatcctgaca atgttgggaa ttatcatcgg tgtagcagca gttgtgatta ttatggggtt
    24661 gggaaatgct atgaaaaata gtgtaacaag cacattttct agcaagcaaa aagatattca
    24721 actctatttt caagaaaaag gagaagaaga agacctgtat gccggattgc acacgcatga
    24781 aaataatcac gaagtgaagc cagagtggtt agaacaaatt gttaaagata tcgatggtat
    24841 tgattcttat tactttacca attctgctac ttctactatt tcgtatgaaa aaaagaaagt
    24901 agacaatgct tcgatcatag gggtaagtaa agattatttt aacataaaaa actatgatat
    24961 cgtagctggt cgtacactaa cagataatga ttattctaat ttttcgcgta tcattctttt
    25021 agatacagta ttagccgatg acctatttgg cgaaggtaat tataagtcag ctttaaataa
    25081 agtggtaagt ttatctgata aagattattt agttattggt gtttataaaa ctgatcagac
    25141 gccagtttct tttgatggat tatcaggcgg cgctgtcatg gcaaatactc aggtagcttc
    25201 agagtttggc accaaagaaa taggatctat ctacattcat gtgaacgata ttcaaaacag
    25261 tatgaactta ggaaatcaag cagctgatat gctaaccaac atatcgcata ttaaagatgg
    25321 acagtacgct gttcctgata atagcaaaat cgttgaagaa atcaatagtc agttcagtat
    25381 catgacaaca gtcataggtt caattgcagc gatctctctt ttagtgggag gaattggtgt
    25441 tatgaatatt atgttggtat ctgtcacaga gcgaactaga gaaattggtt tacgtaaagc
    25501 acttggtgca acacgcctga aaattttatc acaatttttg attgaatccg ttgttctaac
    25561 agttcttgga ggcttgatag gattattatt agctcaatta agtgtagggg ctttaggaaa
    25621 tgcgatgaca ttaaaaggag cttgtatttc tcttgatgtg gccttaatag cagttttatt
    25681 ttctgcctca ataggtgtct tttttggaat gttgccagct aataaagcta gtaagttaga
    25741 tccaattgag gcattacgtt atgaatagaa tagttcgtat caattaatct atagacgctg
    25801 actagtttaa cgtctgatta tatctagttt ttgtattagc acagtagtta tatcattgaa
    25861 gtgttagtgc attttttgag gtgataatat ctagcaaagc tatcattggt atgatgatgt
    25921 ggatagcgta taagtgatac atctcttatt tctagctgaa cttcggttcg gctaggaagt
    25981 tgtcaggcaa tgagttgttt aaaataaagg agattagttc aatgacattt ttatctgatt
    26041 tgatatcatt aatgacaaaa atcagattat cttgggtaat aaaggcgggt atttttcaat
    26101 tattatttgt aacgattgct aatattgtct tatcagaatt tttctatttt atattagacg
    26161 ttactggtca atatcattta gataaagaca atgttgtgac ttttttaaaa aatcctatag
    26221 cacttgcttt attaggtgcc tatttatttt tattagctgc ttttattcac cttgagtttt
    26281 ttgctctata tcgaattatt gcggatcaag aaattagttt ctatcttttt agaaaacagt
    26341 tttcttatta cctaaggggg ctttggaaaa cattttctgg ttaccaatta ttactttttt
    26401 tgctttatat cctattgact attccagtct tacatattgg tttatcttct gtgattactc
    26461 aaaagcttta tcttccagaa tttattgttg gggaattatc aaagataact agcacaaagt
    26521 acttgcttta tggcagtctt attcttgtat tttaccttaa cctaagatta gtatattttt
    26581 taccattgat agcaatcaac catcgtacgg ttgctcaagc atggagagag agttggcaaa
    26641 agactaaaaa gaaacatgta ttgttatgga tgaaactttt tgcaatcaat ggtcttacgc
    26701 ttgtagtcgt atcgctagct atttccatga ttcttatttt tgttgatatg tttaatccta
    26761 aggggaataa tattattgtt cagctgggag ctttgacctt tacatgggag ctcatttttt
    26821 ttactactat tttttttaaa ctctgttcag caatgatttt aaaagaggca attgaaccac
    26881 aaaagcaata tgatgagcca agaagaagta ataaggcata tgttgtaatc tttatcgtgg
    26941 tgacagtagg ttttgcttat caatctcttg aacgtttaac tttttttgac acatctcact
    27001 ctaagacagt tatcgcgcat agaggacttg tatcagcagg tgtagaaaat tctctggaag
    27061 cccttgaagg tgctaagaaa gcaggaagtg attatgtaga actggatcta atcttgacta
    27121 aggataatca ctttgtggtg tctcatgata atcgattgaa gcgtttagct ggagtaaata
    27181 agacgattcg caacttaacc ttaaaagaag ttgaacatct aacgagtcat caaggacatt
    27241 tttcagggcg ttttgtttct tttgacactt tttatcaaaa ggctaagaag ttgaatatgc
    27301 cattacttat tgaactcaag ccaattggta cagaacctgg aaattatgtc gatttgtttt
    27361 tagaaactta tcatcgactt ggtataagca aagataataa agtcatgtct ttagatttag
    27421 aagtaataga agctatcaag aaaaaaaatc catcaattac gactggttat atcataccaa
    27481 ttcaatttgg cttttttgga gatgaatttg ttgatttcta tgtcattgaa gacttttctt
    27541 atcggtctta tttgtcgtcc caagcttttt ggaataataa agaaatttac gtttggacta
    27601 ttaatgatcc caagcgcata gagcattatc tcctaaagcc tattcaggga attattacag
    27661 atcaaccagc tttaactaat caattgatta aagacttaaa acaagataat tcttatttta
    27721 gtcgattagt cagaattatt agtagtcttt attaaaggtt taaagaaagt gtcaagaaaa
    27781 aaacttgaca ctttctttaa actgagttat actgtttaac ataggaattt agcgtagctg
    27841 tatttcttat acattactaa aagaaaagag actatttaaa aatggcagta aaaatccgtt
    27901 taactcgtat gggttctaag aaaaaacctt tctaccgtat taatgttgca gattcacgtg
    27961 caccacgtga tggtcgtttt atcgaaacag ttggaacata caacccatta gtggctgaaa
    28021 atcaaattac tattaaagag gatcgtgttc ttgagtggtt atctaaagga gcgcagcctt
    28081 ctgataccgt tcgtaacatc ttgtctaaag ctggtgttat ggctaagttc cacgaccaaa
    28141 aattctctaa ataataacag cctatggata ccattgaaaa tcttattatc gctattgtga
    28201 aacctttgat ttcacaacca gataatctta ccattaaaat tgaagatact cctgactttt
    28261 tagagtatca tcttgacttg gatgctcaag acatcggtcg tgttatcggc aaaaaaggtc
    28321 gaactattac tgcgataaga tcgattgtct actcggttcc aacactagga aaaaaagttc
    28381 gcttagttat tgatgagaaa taatcactaa cttgagatgg attgaaaagc ttgttgactt
    28441 aaagtcaaca agctttttga atagcaaaaa tcttaatatt tctgaaatga aaagattaga
    28501 tttttctgtc tttaactaaa aagaagttaa agaatggctt agctgattgc ctttataaga
    28561 gattatactg gtttttgata gctgctgtca tgtaaaatag ctacaattca tcttacgaga
    28621 ttgaccttag cattgccagt gcagtcttta ttttctaacc tgctgtttgt tgtatgttta
    28681 tagtttccta aaaaatgctc tctcagtttt ttgggggaca ttcctaaaat taagtatact
    28741 taatttt
//
LOCUS       DATWVB010000018        27733 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.018, whole genome shotgun sequence.
ACCESSION   DATWVB010000018 DATWVB010000000
VERSION     DATWVB010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27733
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.018"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            284..1036
                     /locus_tag="VCX65_000968"
     CDS             284..1036
                     /locus_tag="VCX65_000968"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEP5053435.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            1092..2165
                     /locus_tag="VCX65_000969"
     CDS             1092..2165
                     /locus_tag="VCX65_000969"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEP5053436.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSLERVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPE
                     AIIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(2600..2905)
                     /locus_tag="VCX65_000970"
     CDS             complement(2600..2905)
                     /locus_tag="VCX65_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEP5053437.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKAHHLEAKTDCKLLQVLLD"
     gene            complement(2907..3245)
                     /locus_tag="VCX65_000971"
     CDS             complement(2907..3245)
                     /locus_tag="VCX65_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEP5053438.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAAIPHALYAVEAFQ
                     MLLVVVKPEA"
     gene            complement(3298..4053)
                     /locus_tag="VCX65_000972"
     CDS             complement(3298..4053)
                     /locus_tag="VCX65_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEP5053439.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVTVEGLTRHITVSQANALSLPF
                     PDNHFDIVINEAMLTMLNAKAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            complement(4305..5183)
                     /locus_tag="VCX65_000973"
     CDS             complement(4305..5183)
                     /locus_tag="VCX65_000973"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEP5053440.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEIRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            complement(5321..8827)
                     /locus_tag="VCX65_000974"
     CDS             complement(5321..8827)
                     /locus_tag="VCX65_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEP5053441.1"
                     /translation="MVYRQKSSEIVTRTITKPSRATSNVKQEIDMTPDSKEQTVTGYQ
                     YHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSNWQVIHLPHDFSLTQPYTRNGEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFALNQSIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFMANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENASYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWIAAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYDKLHEEHSDWLLYGSET
                     ASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNVTDYGRKAFHTYSTPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQVEGPAHLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKVSQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVSTPHILITSYQHY
                     LSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLATSQKRLTYCYQYDTVQAIGA
                     ISLQNHTDTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLVVT
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            complement(8757..10241)
                     /locus_tag="VCX65_000975"
     CDS             complement(8757..10241)
                     /locus_tag="VCX65_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5053442.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFDVVSTARSGQEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTNHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDWLDAQQAESIRQETYHDSLLTLWLTDELSEKEFHQLSQD
                     LPEHALTGFTVLYVECSEWIEEMEAYFKQEEQPCYLKKEEDKKIYLAILLGRAQQAKA
                     FTSNLQKQFSENIQQIILGETVDDWENVYESYNQVRQSLFYNSQMSQPTDKGNSKLEM
                     PESRLQFFAFNKALMIGDEPTILAKLEAIFHEMKALNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHNSQSIDRILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            complement(10241..11965)
                     /locus_tag="VCX65_000976"
     CDS             complement(10241..11965)
                     /locus_tag="VCX65_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP5053443.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQLQNDITLRVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADRVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRHDNALSIKALDETDHLLIQVLDN
                     GRGISQERLADMEKRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDV"
     gene            complement(11955..12560)
                     /locus_tag="VCX65_000977"
     CDS             complement(11955..12560)
                     /locus_tag="VCX65_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEP5053444.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTITYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     TLMTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            complement(12866..14311)
                     /locus_tag="VCX65_000978"
     CDS             complement(12866..14311)
                     /locus_tag="VCX65_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP5053445.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKTQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            complement(14392..15318)
                     /locus_tag="VCX65_000979"
     CDS             complement(14392..15318)
                     /locus_tag="VCX65_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEP5053446.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            complement(15328..16278)
                     /locus_tag="VCX65_000980"
     CDS             complement(15328..16278)
                     /locus_tag="VCX65_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP5053447.1"
                     /translation="MTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIVFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLVGSG
                     ADPIKWYSNPTWWPLILLFMSGWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            16474..17352
                     /locus_tag="VCX65_000981"
     CDS             16474..17352
                     /locus_tag="VCX65_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEP5053448.1"
                     /translation="MSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAISSPGAINKEKGVIEGASAIPYIHHFKIQEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVLGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALAEQGDHLALKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            complement(17963..19405)
                     /locus_tag="VCX65_000982"
     CDS             complement(17963..19405)
                     /locus_tag="VCX65_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEP5053449.1"
                     /translation="MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYD
                     YVGPDTASDAYHQIESDLALLASLGHNSYRTSIQWTRLIDDFEQVTINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRQGPAELSDGR
                     IGTILNLTPAYPASQSEADMAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDVIPVISPSWSPEWYYDAYLMPGRRMN
                     VDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIRF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(19430..21124)
                     /locus_tag="VCX65_000983"
     CDS             complement(19430..21124)
                     /locus_tag="VCX65_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HEP5053450.1"
                     /translation="MTIYHALKDYQEVMTRGDYLVFDMPLTCRFIGRFFRFENQKALL
                     AELATSKYFQWIEEGQAELTVKHFFNRQLDKDAFTLKVSEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFAMRGIIEGFYGTPWTREERLDCLRFIGRKRM
                     NTYMYAPKDDDYQRKLWRDLYPEDWVTYFKELLAVAKEEGIDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQSDYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSNSWLETLTDYTGDAELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKDVSTLSAWVDELVERVNTLRKLDKPAFQQAIVPWFERVAKDQDFWQAI
                     LEQGPHLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            complement(21175..22215)
                     /locus_tag="VCX65_000984"
     CDS             complement(21175..22215)
                     /locus_tag="VCX65_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP5053451.1"
                     /translation="MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAEKQVTSPEANKDLLLILPFTSDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQKITQVG
                     LYIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            22348..23634
                     /locus_tag="VCX65_000985"
     CDS             22348..23634
                     /locus_tag="VCX65_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEP5053452.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFTNTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANGKGHQTDRTQMNPWIWERKYEIDSLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNEPVATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCAKDDPIYLATRRTILSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSITP"
     gene            23649..26354
                     /locus_tag="VCX65_000986"
     CDS             23649..26354
                     /locus_tag="VCX65_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEP5053453.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDP
                     DFHSFHLDGQTIILDDYLQVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLSDLANDLPDNL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYP
                     HDQLRYAWKTLTQNHPHDSICGCSVDSVHREMINRFEKAYEVGHYLAKEAAQQIAGAV
                     NTSDFPTDSQPFLLFNTSGHSKTSVTELTLTWKKYYFGQRFPKEVYQEAQEYLAGLSQ
                     SFQVIDVSGNTISEADILDTSIAFDYDLPKRTFREPYFAIKVRLRLPITLPAMSWKAL
                     ALQLGNETAPSATVPLYDDSNQCLENEFLKVMIQTDGRLTITDKQSGVSYQDLLRFED
                     CGDIGNEYISRQPTHDQPFYADQGTTKLNIISNTAQVAELEIQQTFAIPISADKLLQA
                     EMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNE
                     YEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWR
                     AQEGQVPILVEQTSHHKGSLRAEHSYVTGADDQVALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(26455..>27733)
                     /gene="rocA"
                     /locus_tag="VCX65_000987"
     CDS             complement(26455..>27733)
                     /gene="rocA"
                     /locus_tag="VCX65_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HEP5053454.1"
                     /translation="SFVSAIPLRLKNIFYLSLSMVLFQVVFWAFFPDHFILDVVMLAQ
                     FLFFALIALYYGKSIKAKFLMFYAFFPLVSISLVKRFIVFFVMPLFGMPYSVVKHNTL
                     LIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQSHRASKLLVFTNSSMALYYLCVQGID
                     VMSPSLSGLATTTARSIIVLFYFILFLTLLIHLERYVKQNSIEAIVQQKEYRELINYS
                     QHLGLLYQDIQELRQLLTTVSSRLKIGIEQNDISIVRLTYEGILNAEKNNAKDDRLDL
                     TCLDKLQVEAIRHIVLAKLIEAKNKKLKVEVSIPNCIATFFLEVVDFTKLLSFLLDNA
                     IEMSLETKQPCLSIAFLDQNHKLVIVIQSSTKQGQNDSQSVFATPALKKRDDWQFDLR
                     NVTTILNRYDYLTISSQIHDGILTQLIEIAKPD"
BASE COUNT         8306 a         6047 c         5334 g         8046 t
ORIGIN      
        1 ttaaaaacta taagaaaatt tctaattatt cccggtggtg gcatctataa aaaatactgt
       61 cctaataaga tttggggcag tattttttta tagctagcaa gcctttttta ataaaaatga
      121 ctaagaacat agacaatcta gggtttactt gctatttcat cttgtttatg gtatcatttc
      181 acaggctaag ggtgcttcat ggataacaac gagattttgt attcctaaat aagacgttat
      241 cccatagagc acgccataca gaattagtaa aggaatcaaa cgaatgattg acattatgtc
      301 tgactttcaa aataagactt gttctaagaa taattttatt gttggacctt gttccattga
      361 atcttatgat cacattagat tagcagcttc aagtgccaaa aaacttggtt acaactattt
      421 tagaggaggc gcctataaac caagaacatc tgctgcttct tttcaaggcc ttggcctgca
      481 aggaattcgt tacttgcatg aggtttgtca ggaatttggc ttactatcgg tcagtgaaat
      541 catgtccgag cgccaattag aagaagccta tgactatctc gatgtcattc aggttggtgc
      601 ccgcaacatg caaaattttg aatttttaaa aaccttgtca cacatcgata agcctatttt
      661 gtttaaacga ggcttgatgg ctactatcga ggaatatttg ggcgcccttt cctacttaca
      721 agacactgga aaatctaaca ttatcttatg cgaacgtggc gttcgtggct acgatgtgga
      781 gactagaaat atgcttgata ttatggcagt ccctattatt caacaaaaga cagatttacc
      841 gattattgtg gacgtgtctc attcgacagg cagacgagat ttactcttac ctgctgctaa
      901 gatagcgaag gctgtcggtg ccaatggcat catgatggag gttcatcctg atcccgacca
      961 tgcgctgtca gatgctgccc agcaaattga ttataagcaa ttagaacagt tggggcagga
     1021 actttggcaa gattaagctc taaatatcac tgcgttatct ctgttaccta gtactgatga
     1081 aaggagtgct tatgccacaa acacttcatg tccattctcg ggtcaaggat tatgatatcc
     1141 tgtttaccga ccatgtttta aaaaccttag cagattgcct tggtgagcgc aagcagcgta
     1201 aactcttgtt tatcaccgat caaacggtct accacttgta tcagactctc tttgaagaat
     1261 ttgctcagca atacaacgct tttgtccatg tctgccctcc gggaggtcaa tccaaatcct
     1321 tggaacgtgt cagtgctatc tacgaccagc tcatcgctga aaatttttcc aaaaaagata
     1381 tgattgttac tattggtggt ggtgttgttg gggatctggg tggttttgtc gctgcaacct
     1441 attaccgtgg tattccctac attcaaatcc caacgacttt acttagtcag gtggatagca
     1501 gtatcggggg caaagttgga gtccatttta aaggtctaac caatatgatt ggcagcattt
     1561 accctccaga agctatcatt atttcaacca cctttttgga gaccttaccg caacgggaat
     1621 tctcctgcgg catcagtgag atgctcaaaa tcggcttcat tcatgataga ccgctttttc
     1681 agcagttacg tgattttcaa aaagaaaccg ataagcaggg acttgaacgt ctgatttacc
     1741 aatccatttc caataaaaaa cggattgttg aacaagatga atttgaaaat ggtttgcgca
     1801 tgtctttaaa ttttgggcat accttgggcc acgcgattga atcgctctgt caccatgatt
     1861 tttaccatca cggtgaagcc attgctatcg gtatggtggt tgatgctaaa ctggctgttt
     1921 ccaaaggact cttgccaaaa gaggacttgg atagcctcct tcaagttttt gaacgttacc
     1981 agttaccaac aacacttgaa agagctgatg tctctgcgac atccctcttt gacgtcttta
     2041 aaacagataa gaagaattct gagcaacata ttatctttat attacccaca gaaaccggtt
     2101 ttaccaccct agccattaac aaagacgatc accaatttgt cgagaagctc gacagtttat
     2161 tataaatagt gactccactc tagctagtta agcttgctaa gagaataacg gtatcctgga
     2221 actcctaaaa catgttacta caagacaagt cttgataaca atataacttt tagctaagaa
     2281 taactaacag caacatcaaa aagaggattt atggaactat aggagaacgg tatcactcgt
     2341 aaaaagatct ttcttttgcc tgtcgttcaa ttatttcgtc taaaaagcct taatgagaaa
     2401 cctataagga gataggaaac tcattaaggt tttttagtga attctaaaat aaaccaagct
     2461 aaagggctta atctggagat gagaaggcca agctttaaaa ttcgtattgt catcgctttg
     2521 aatacgtaaa aagagaagat gagcgtcatc ttctcttttg cttttccata ggccacccaa
     2581 tacagttgac aataagccct taatctaaaa gcacttgtaa tagtttacaa tcggttttag
     2641 cttctaaatg atgggctttt tgggcaggta tggctatgag actttcttga gttaggacct
     2701 gtttttgatc ctctaaatcg aaaatgagct gaccttctaa aacaagtatt actttatctc
     2761 ttggactagt ctcttgacta atgctttctc cttgggccat ggcatataaa acaatagatt
     2821 gagataatcc cagtagacgg ctcaaggatc ggctagccac ctgatgatca tgatattgca
     2881 ccagttgaga gagattttca atcatgttaa gcctccggtt ttactactac taaaagcatt
     2941 tgaaaggctt ctactgcata taaggcatga ggaatagcag ctggcatcac aatggtttga
     3001 ccttcagcaa cccggtaggt ctcttgatca atggtgattt ctgctaagcc acttaagata
     3061 gtaaccatgg catctcctgg tgatgagtgt cgcccaattt cttggccctt atctaaggaa
     3121 aaaactgtta ttcctaggtc ttgcctttgg actagtgttc tacttaacat ttgatcttgc
     3181 tcaatcatta cttcttgcgt caaatcaaga accttcgcgt gctcaatatt attgatataa
     3241 gacatcttcg aactcctcta tggtctgttt agttgtatgg acaggttggt ctaaggttta
     3301 ttttacactt tttacagcaa tatagcagag atttttgcct gttctggtaa aaaaacgacg
     3361 catctttaaa aactgttgtc tgttctcttt cttaaggcct cgtctcataa tgttcagggt
     3421 gttcataaga ccttcatcct taatcattcc acgaggtgtc atcaaagaca ttttcccatg
     3481 gtgataagtc acttgagaaa aaccgtgttc ttgatataag gcttgccaac ctgttagtga
     3541 caagggagca acattgacat gaatcgtttg acgtaactcg tcaagtactt gtcttgtttt
     3601 tggatcttca taagctacgt catgtgtcaa aagtcgcccg cctggtttta acacacgcca
     3661 atattcattg agtgccttct ccttggcttt ggcgttcaac atggttaaca tggcttcatt
     3721 aatcacaata tcaaaatggt tatctggaaa tggtagtgat aaagcattgg cttgggatac
     3781 tgtaatgtga cgggttaacc cctcaacagt aaccctttct tgtgcttctt tgacaacctt
     3841 ggggtttaag tcaacggcat caatctgaca accgaaggtt ttggctaact ctattgctgt
     3901 cgtgcagcga ttgcaggcaa cctctaaaac gtgacaatcc tgagagaatt gtccttgttc
     3961 aatcaaccag tttgtcgcct caacaccgcc aggtcttaag cgtttttttc ctagacgtgc
     4021 taaaaagtca tgcccaactt cctttgttac cattgctatt ctcctttatt cattgaactt
     4081 ttccttttat aagagcttct tttctaaaaa aacggtaggt tatctggcag acctcaaagg
     4141 aactatgact tgtatcacgt tagggataag gctcttcaaa taagcttttt actcttaaaa
     4201 acagctctcg caaaaagaat tttagcagcc catgatgact gctccatctc ttattaatat
     4261 atcataatta agcttactta aaaagttctt taaaaaaggt tgagttactc atcacctaaa
     4321 agaggtttaa tagcgtcaac tggcatgtct tgaccagtga ttaatttaaa agcttctgct
     4381 ccttgataaa gcaccatccc tagcccatta atgacttttt gggcgccatg ttgacgggca
     4441 aaggctagta acttggtttc tgctgggctg tacacgatgt caaagaccac caagtctggg
     4501 cgaatgagct cggggtcggt aatcaaactt agattttcta aaggcttcat tcctacactt
     4561 gtagcatcaa taaatagatg agattccctg atggcctcct taaaggcagt ctgatcttcc
     4621 aagtcttgaa gggttacttt agtccttgtt agctggttca gttttgtcac aagcttttga
     4681 acgctactta gacgtgtagc ttgtcggtta aacaaacgaa tctctttggc gccgtcaaaa
     4741 gcgagctgga cagcgatagc tttcccagcc ccaccaactc ctgctagggt aatgattttg
     4801 ttctttaccg acactccttc gtcagccaag gctctgagcg ctcctatgcc gtctgtaata
     4861 tgccccacga gatgtccttt accatcctta ttgacaaccg tattgactgc accgaccaac
     4921 tcagcagctg gggacaagtc atccaataag ggtaaaatag cttctttatt tggcatagac
     4981 acattggagc cacgaattcc taaggcacga atcccttgca cggcatctgc taattgctct
     5041 gtccctactt caaaagcaag gtaggcataa tccagcccca gtttagcata ggcttcattg
     5101 tgcattttgg gagacaaact atgacgaata ggagtagcaa gcaaagagac cagcagggtg
     5161 tggcctgata aacgttctga catttagaaa tctcactttc catttcaacc ttgtaaaggc
     5221 gcctttcacg taataaagga cgcctatttg ttttttatta taccttattt tacaaaattt
     5281 atcagacctg gtgccaaaga agtcttcttt tacttatgct tcatgctaaa tcccaaaggc
     5341 caatttgaat actgtcttca gttaggtcag gtccttcaat gacttcaagg gtcactacta
     5401 gatacaaaac agtcaaaata tcatcgaaga aaataacctc ttctaactgg ctcaagtggc
     5461 tatcagctag catcaaggtt tcttgcttaa tagagctctg actaccataa ctgattgcca
     5521 cagaaacact aagagatgtg tctgtgtgat tttgcaagct aatggctcct atggcttgca
     5581 ccgtatcata ttggtagcaa taagttagcc ttttttgact tgtggccagg gattgcttgg
     5641 cgactaaact gagatcctgg tgccgtcttt tgctagcttg tgctaggtta agccttgcct
     5701 caaccggtat tgattgccca aaacaagaaa catagcccgt gacaagaata ggcttggcaa
     5761 agattttctc ttttaggtac catgtcattg gaaaagcttt tttcacaaaa gaaccttggg
     5821 catctttgac ttggagccac tgaggcaaga agatatcgtc gcctttttta aaatcaaatg
     5881 cctgagaaca aacctgcaag ggcagagata aatagtgctg gtaactggtg ataagaatgt
     5941 gaggtgtgct aaccttacct gctttttgct gggtgtcttt gttctccaaa acagaaagga
     6001 attgtgtggt ctttagacaa gattgaccaa tttcttgttg acttgtcagt cggctctttt
     6061 taaactgata tttctctaaa ggtagtgtca ctaagtgttc tttgggggca cggcaggcta
     6121 cttgtgtctg aaaaacactg ctaagttgct gcgagacttt tgccgtgacc ttaatgtgtc
     6181 ccgcctctcc agtgagggct aaaatggcta ataattttcc cccatatgcc tggcgtagag
     6241 gctcctgata aggggtgtgg tcagtcggat tcccattatc aagagccaac aaatgggctg
     6301 gtccttctac ttgaaccttt agccaatctt gagcatggct gaccaattca cctcggctat
     6361 ccaagagtga taaatccaga taaagcaatt cccaaggagc gtcaataggt gcttcaaagg
     6421 ctttccaaga tagctttgcc actgaaccat aggttctaac ctgagaacgt ccactggttt
     6481 ttggaatgct tttaccagaa atgtcgtagg ccactgccct tagcaaccct ttttgatagg
     6541 gcactcgcca agtcaggtaa agattctcgt gaggattctt agcagcgtca gctccttggt
     6601 aaagctgata agtgtgtccc gttggcgtgc tataagtatg aaatgccttc cttccataat
     6661 ctgttacgtt gccctgctca tcttcaaaca tcagttgaac actggcagca ttgctataaa
     6721 ccacaacctc caccaatccc tgctcatcga aacaaagctg gtccttctgc cagactggta
     6781 acaggtgcaa ggtggtctgc ccctgcgccc actgactttg gtaaaaataa tagctatctt
     6841 ttggaaagcc tgccgtgtct aaaatgccaa agtaggcatt tttaggagaa ggccaaaggc
     6901 ctacaacacc gctgtcgatc ttgttccagg gtgtaggttc tcctaaataa tcaaagcctg
     6961 tccaaacgca ttcgccagca acaaaatcac gggtaatggt atcataccaa gcctggctag
     7021 cgaatgcacc ccaatcgacc ttagcatgat cataagaggt taggtgataa ccggagtcaa
     7081 gaactttttt tgtctcttta taataagccc tgctggtaat ggctgaggct gtttcagaac
     7141 catacaacag ccaatcagag tgctcctcat gaagcttatc atagtctttt ccattagcat
     7201 agtttaaccc aatgagtccc tggggatggt ctaattgact aagaagagtt gccatttgcg
     7261 acacttcctc atgccagcaa aagtcagctt cttttaattt attgtcccca aaggtaatgg
     7321 gacgtgaggt gtcaatagca gcaatccatt ggcacatttg tcttgttagc tctgggtaat
     7381 gactgacatc ggctgaaaaa ccttccatca attcattccc aatcgaccac atcaacactg
     7441 acgggtcatt cttggcagac cagaccatgg cctcaatact atactgggcc cagctcgttt
     7501 caggtgacct cactctttga agatagcttg cattttcagt tccgatggtc tgatggaaat
     7561 agtttgaaaa gtcattaaca tttccatttt tggcataggt ccaggtgtca aaggcttctt
     7621 caatcacaaa aaagccgaga cgattggcta gttgcctaag tttgggacta cttgggttat
     7681 gggtgctacg aatggtatta gcccccatgt ctttcaacag gactaattgt ctggctaggg
     7741 catcttcgta agcacaagct cctaggcctc cttggtcatg atgcaaacaa actcccttta
     7801 atttgacagc tctgccattc acaaaaagcc cctgattggc cataaaagtc agctgacgaa
     7861 aaccagtttc aaggcaaaag caatcaatga cctgaccttg atagtaaaga gtgagttcta
     7921 aatcgtagag gtgaggatta tctggtgacc acaattggag ttcttccaaa gacagtgtaa
     7981 gaccatactg tctttggaaa gccaaatcag ctagaggcac ttctgtttct tgataaagga
     8041 gtttcttgtc ttttgagcaa tgtgattgtt cccataaaca gaggctcaat tggtagtggc
     8101 aagtctgaat agactgattg agggcaaagc gtaaatcaac tttctgttgc cctttctcct
     8161 gcacagcagt atcagccaag gtcattgcta cctggtctgc cacaaaatga agctggggaa
     8221 gaacagacaa actcacttca cgataaagac cactgcctga ataccaacga gaactgggaa
     8281 ccttgttttc aacccggaca gccagaagat tttcagctcc aaaagtcaca acatcagaga
     8341 tatcataagt aaattcctga tagccattta agtgtttgcc aatgaattgc ccgttaacat
     8401 aaatttccgt ttccatatag gaaccctcaa aagtaatggc aacatgacaa ccagctaaaa
     8461 cctcatctaa cacgagataa tgccgatacc aaccgacacc acctaattta taagcacttt
     8521 cagcttcacc atttcttgtg taaggctgcg taagactgaa atcatgtggt aaatgaatca
     8581 cctgccagtt cgaatcatca aaagaagggt cctgagcaca cgccacatct gccataagaa
     8641 aacgccagcc ttgattaaag ggctgctttc ttccttcttg atcaatatag tggtattggt
     8701 agccagtcac tgtctgctcc ttgctatctg gtgtcatatc aatctcctgt ttgacgttac
     8761 tggtcgccct tgatggcttg gtaattgtcc ttgtaacgat ctctgaactc ttttggcgat
     8821 aaaccattca actttttaaa catcttgata aaataatgat tggtattgta acctgtttca
     8881 taagcaattt cattgatgga ttggttggtg taaagcaata actgttgcgc tttttgaatc
     8941 ctaacatgat ttaagtactg ggtaaaacta cgctcggttt catttttaaa gcattgccct
     9001 aaataaaccc cattgacatg taacctatca gcgatagctt taagggttaa ttcttgatgg
     9061 tattccttgc gaatgcaatc aatggtttca ctaactaaat ctgaataacg tttttcaggg
     9121 gaattgttct gattggtgac atccaacact ttttttagtt ccctcaaaat gcgatcaatg
     9181 gattggctgt tatgaatagt ttttaccatg gacagataag tcattttatc taaaatggga
     9241 aattgacggt aaatgtcaga gaacaacaag aacgacacat gcttcacatc ctctggtgag
     9301 aagttcaagg ccttcatttc atgaaaaatg gcttctaatt tggccaagat ggttggctca
     9361 tcaccaatca tcaatgcttt gttaaaggca aaaaattgca accgagattc tggcatctca
     9421 agcttactgt tgcctttgtc agttggttgt gacatttggc tattgtaaaa aagactctgg
     9481 cgcacctgat tgtagctctc ataaacattt tcccagtcat caaccgtttc tcctaggatg
     9541 atttgttgga tgttctctga aaattgcttt tgtagattac tggtaaaggc tttggcttgc
     9601 tgggctctcc caagtaaaat cgccaagtaa atcttcttgt cttcttcttt tttgaggtaa
     9661 cagggttgtt cttcttgctt aaaataagcc tccatctctt ctatccactc ggaacactcc
     9721 acatacagca cggtaaatcc tgttagggca tgctcgggga gatcctggct aagttgatga
     9781 aattcttttt cactaagttc atctgttaac cacagtgtca gaaggctgtc atgataggtt
     9841 tcttgccgga ttgattcagc ctgctgggca tccaaccagt ctttaaattg tttcatttta
     9901 gcctgcaatt ctgccttatc cacaggtttt agcaaatacc ccttggtttc taattccata
     9961 gccttttgca cataggagaa ttcttgataa ccagataaaa tcaaggtttg tagctgagga
    10021 tgattagttt tagctgcttc tattaaatcc agtcctgtca ttccaggcat ggtaacatct
    10081 gaaatcatga catccactgg gtactgagtc aaataggcta aggcttcctg gcctgatctt
    10141 gctgttgaaa cgacgtcaaa accaagagcc tgccaatcaa taatcatggt taatccttgt
    10201 agaatcatgt attcatcgtc aactaataat accttataca ttaaacatcc tttctaatcc
    10261 taatttgaat gataaagcca ccatttggct ccttagccat ggaccaagaa accctgtctc
    10321 gaaaatgatg gaaaagacgg aggtaaacat tttgcaaacc aatagagcta ttgcctgttg
    10381 tttggtgctc ttgaagcctt ttttccatat ctgctaagcg ctcttgacta ataccacgtc
    10441 cattatcaag cacctgaatc aagagatgat ccgtctcatc taatgccttg atgcttagtg
    10501 cattgtcatg gcgactataa tcaatcccat gcacaaaata attttcaacg agaggttgaa
    10561 tgacaaattt aggaatggct aaatcagcaa tactctcatc aatttttaca tgataagcga
    10621 agctatctgg ataccgcatt tggtagaggt aaatgtactt ttcacaaaaa gccagttctt
    10681 cttttaaggt ggtcatctta tcttggctaa tattgttgcg aagcaaactc gcaaaggcat
    10741 aaatgacatc tgctaattct tcttgttgac aactaagggc gtacatccga atatactcta
    10801 acgtgttgta taaaaaatga gggttgattt gagactgcag agctctcatt tgggcatctc
    10861 gttgctctac ctctaacaca taaacttcgt caatataagc tttaatgctg gccaacatct
    10921 gattaatggc ttctgagata tgatacagtt ccaattccat gtggctgttg tcgatggtta
    10981 aagacaaatc gcctgctgca accatttcaa cagtatccgt aatttcagaa acctgctgga
    11041 tataatttcg gaaaacccta aagagcaact gcaataacag ccaagctaag agtagagaaa
    11101 caaggccata cacaaaaact gtcctgacag cttccgctaa taaataggat tttctgacag
    11161 ccacataagc taagaggtct cccgagcgat tgtactgcat ccgataagcc ttgctgagat
    11221 tactaagatc agctgcccga tctgccttga tagccttttt aacctcagcc tctaaatgag
    11281 gaaatctccg acctccttga tggaagagtt tgcggccata gtaatcaaaa gcaaaagtag
    11341 ctaaatagtg atcctgctgt gtctctacca aagtcggtgg tttgtcaaag gtcaggtaaa
    11401 gacgacctgt cacatctcct gattctggat ttcgaatgga gcgaactaaa acatttccgg
    11461 ttactttttc aggcttgcta taaagcaaac gacccgtctt aatgacccta tcggcgtaca
    11521 gataagcact actgtcctct agcagtaggg tcatagaagt cacatcaggg tacaagtcaa
    11581 aaagacgcct cacctcttca gaaaatagga ccgtgtcttt tcctttttcc cagtcttcaa
    11641 aaacgtttga aaaatattgg tttggggtta acgtcatata ttgatagagg ttatggtaat
    11701 cttctgaacg gccaaccaac tggtctaaaa cccgtagggt aatatcgttt tgtaactgca
    11761 atctacctag agtctcctcc agtcgcatct gcgcctcagc atccaccctt ttataagtac
    11821 tactaataga ataactgctc aagccaatag ctgctaaagt gaaaaaactt acaattagca
    11881 ggctatataa tttcatcagt cgattaatca aaaaaccctg cttaaagtgg ttagtcacat
    11941 accttcccaa tgttttaaca ctcatcaatc actccatcta ctagtcgacg attagcctta
    12001 gtgacaaagt ccaagcaaaa gactagagct ccgaaggtta aaaagagata aaggcctttg
    12061 tattgccaag tcattaaggt aattcccagc aaaacactca gcatgagtaa aaaggatttg
    12121 aaacttaaaa agacgctgat aaaggctaat ttcatattat tccaaaggtt aatctcatag
    12181 ctcactgcat aaaaaaccat gtaaagatag gtaatggtta gccaaaccat ggctattaca
    12241 atcaagaaag acacggtaaa ccaaaacaag gatggaaact gtactgccca atgcaaatta
    12301 aaggttaaaa aaaggaaagt cagggcaaaa agaccaaatc ttagattagc ttctttgaaa
    12361 taagatttcc aaagttgaac agcccttttc aaagaatagt ggttttcttc ttgaggtgtt
    12421 tttaaaaata gggtgacaat ggtttgccag gctggcccca ccccaaacac aatcagtcca
    12481 gctaaggaca agagatgaaa aatgagggtc aattggatca ttttccaaat taaaaagcag
    12541 gttttttcaa tgccattcat atgatagtcc tctttttctt gttaacactt atagcggttt
    12601 caaggaccag cagctacgag actagtttta gcacccccag taagatgctg gtattagttt
    12661 tactctgatt aatagtttag actcttctaa tatagcacac tttataggct tttggaaacc
    12721 gctttactaa gagtagtaac attatttaca ttaatttttc tccctttata acttccactt
    12781 atttgatgat ccgttttttc cactcatcag aagaaaagag ctgagatttc ccagccctca
    12841 acttataatc aagaaaatga atgccttact tgtctttagc tacaaagtcg tccaattgtt
    12901 tttgaacttc tttttgcacc ttgtcccaac cagcaccttt gaggtctgca agaagttttg
    12961 gaagggcttc gtcaggatcc actgtaccag tattgatact tgctttatat cggttcatga
    13021 catttgaaat atttgataat tccgttttga taacttttgt gtcaacagtg aaaccaagga
    13081 ttggagattc tttagcatcc ttgattgatt ggtcacgttt agcaatcatg tcgtcagtaa
    13141 cagattcttg agtgtaaagg attttattgt taccagtatt ccaagcaccc atgtgcattt
    13201 ttggttgata gccatcgagc agtttgattt tcttgtcgcc aattttttcc caagctttgc
    13261 cttcgacacc ataaacaagc ccatttaaca attcgggatc gctattaaga agagaaagga
    13321 cttcaactgc tttttctttg tttttagata cgcttgatac cacaaagttt gccatttgtg
    13381 cttgtgatgt ggtttttagc ggtttagtca atggacgaga cacgatgtct tttcctgcag
    13441 cattggtcaa gatagtatcg ccatagtcca taggaccttg ggtttcttca cgcataaacc
    13501 aagtgtttcc ttcaagggga taaccttctg tattggtcgc tgcatctgtt ggaatcaaac
    13561 cttctttata ccatttgtgc atcaagcgga gattgttttt aaaggactca tcttcatact
    13621 gattaatgat ggttggcttg ccttcatcaa ttttcacagc aaagggttgg gttttggtta
    13681 atgggtagtc atagtcacct gacatactaa agacttgacc aatagcaaaa gctgctgtat
    13741 ttggttcttt ttcgtggaat tgtttcaaga cattttcagc atctgcatag gacttaatgt
    13801 ttgaaatgtc aaggccatat ttgtccacta gttctttatt gaaagaaagc atctgttggg
    13861 cataaacgtt ggcatctact gggaaggcat agagtttacc gtcaatagta tttcctttaa
    13921 tataggctgg gtctaagttt ttatacgttt tcttagcgta ttttggcatt aacgttgtca
    13981 aatcagcaaa agcacctttt tgtgcattga ccacataatt attggcaaaa gcaatgtcat
    14041 agttttcacc agaggcaatg atggtactca ttttatcatc ccagtccccc caaccgatgt
    14101 attgaaggtc aaccgttgca cctgtttttt ctttgatgcg cttgttagca attgtcatca
    14161 attcatcgaa gttatcaggt ttgtcaccaa cttggtacat caataatttg acatcactat
    14221 cctttgatgc tgacttgctt tcgcaggctg ctaaactaga cgctgcaagc acagttccag
    14281 tcacacacac gattttttgc cactttttca taagtgaagc ctcctaaaaa atgttttctt
    14341 ttgttactaa tgattagata aaatctggtc ttgtgaccag ttccttaagt cctattcctt
    14401 caccccacca atggtcaaac caccgacaaa gtacttttgg aagaatgggt aagtcaaggc
    14461 aatcggcaag gttgcaataa ccacgatagc catacgaact gattcttttg gcagcgatgc
    14521 taagctatct gccatttgtg cactcatgcc agcattttgt gccaaggcct gtaggttgct
    14581 ctgaattttc atcagtaagt actgcattgg gtagaggttt tcactttgca cataaagcaa
    14641 ggcgttaaac caatcattcc aataagttaa ggcagaaaat aaactgatgg tagcaatccc
    14701 tggaacagcc aaagggagaa caattttcat aaaaatcatc cattcactag ccccatccat
    14761 acgagccgac tcaataatgc tatctggaac tgtcttttta aagaacgttc tcatgaccaa
    14821 gatgccaaat gggcccagag ccattggtaa aatcaaagcc caaaccgtat ccttcaaatg
    14881 aaggagatta ctgaccacca agtaattagc aaccatccct ggtgcaaaga gcatggtgat
    14941 aagtgcataa acagtaaaaa aacgtctgta tgggaaataa ggtcttgaaa tcgcataagc
    15001 ataggttgat gtcatggtcg tgttaataaa ggttcccacc actgtaataa acacggatat
    15061 cccaaatgac ctcatgattc tatgggacat ggctccttga aaaatatact ggtaagcctt
    15121 agttgaccag acatctggaa aaaaactata cccatgatta atcaagtaac tttcatcagt
    15181 gaaggaaata ataatcacga agataaaagg aatgatacaa gagatggcaa acagaccaat
    15241 cagaatatta aagatagcat tggtttttcg atcaaaggtt ctaacattaa ccttttcgac
    15301 ttttttcttt ttctccatgt tttcctccta aaacaaggct gcatcaggat ccatgcgacg
    15361 aacaatcgca ttagtgacta acaagatgct ggtcccaact actgactgat aaaggctagc
    15421 tgccgatgcc atcccaatat ctcctgtagc agtcaaggca ttgtagacat aggtatctaa
    15481 cacactggtc acgtcataaa gtgggcctga attcttggga ataacgtaga aaagtccgaa
    15541 atcagattta aaaatattac caatattaat gatcaataag atagacatca ttggcaataa
    15601 ttgtggaatg gtgatgttcc taatttgttg ccatttgctt gcaccatcca ccatagcagc
    15661 ttcataataa gtatcagaaa tccctttgac tgaagcatag tagataatgc tattgtagcc
    15721 tagccctttc cagccactca taaagagtaa aatcaagggc caccaagtgg gattggaata
    15781 ccacttaatt ggatctgctc cactgccaac caagagctga ttaatgaaac ctttatctgt
    15841 atttaaaaag gcagaaacaa agtattcaat aaccacccat gataagaaat aaggcaacaa
    15901 ggacatggtg tgatagacct taaccgttcg cttatttcgt aactcactca tgataatggc
    15961 aaaaacaatc gcaaagaaaa cattaaaaag taagaaaatc acattgtaag cgatggtatt
    16021 tctggtaatc aaccaagcat ctttggaagc aaagagatat ttgaaattag ccaaaccaac
    16081 ccaagggctc tccttcaaac tttccataaa gccccctgct gaataatgaa aatctttaaa
    16141 agcaaccaca ttggctaaaa ctggaatata aaagaaaaag atgaaccaga tgaaacctgg
    16201 taataccatt aataataagg cccggtattt aatcacattt ttccaaaagg atgtcttttt
    16261 gttggtttgt cttgtcattt cccaacctcc ctttgtgtta atcacgttat agttacagta
    16321 tatcaagcgc tttcattatt ttaaagcaac aaattatagg tatgataaca caaagtatag
    16381 aatcacttag aaagcctttt cattgttgct taaatctgtc atactaagat gagacatgat
    16441 cgtctattct actataataa aggagaacac ctcatgagct tgttatgtat tgatatagga
    16501 ggcacttccc ttaaatttgc cctctgtcac aatggccaat taagccagca aagcagcttt
    16561 cccactccct ctagtctgga aaagttttac caattactcg accaagaagt tgctcgttac
    16621 tctgcttacc atttctcagg tattgccatc agttcacctg gggcaatcaa taaagaaaag
    16681 ggggttatcg aaggcgccag cgctattccc tacattcacc attttaaaat acaagaggcc
    16741 ttagaagaac ggctacatta ccctatttct atcgaaaatg atgccaattg tgccgcctta
    16801 gctgaagcta ccttaggggc aggaaaaggc gctagtagcc tagccatgct cgttcttggt
    16861 actggagttg gaggaagctt ggtcattgat ggcaagattt accatggtgc ccacttattt
    16921 gggggcgaat ttggtttcat gatcatgaac gaccgctacc aaacctttag tcagttaggg
    16981 acagtggtaa atatggccaa gcgctatagt gcaatcgtca ataacggaaa agattatact
    17041 ggcaaagctg tccttgccct cgcagaacaa ggagaccacc tagcactcaa agaaaggcag
    17101 gtctttctcc aaagtttagc catcggtatt tttaacattc aacacgcctt tgatcctcaa
    17161 ctgattttaa tcgggggtgg tgtttcccaa gctgactttc tactgtcagc gattgaagct
    17221 gaactagaca aactctacca agccgtcgaa atctccgacc ttagacccca attagctatt
    17281 tgtcacttta aaaacgaagc caatcttctt ggagctgcca ttgattttta ccaagaacac
    17341 aaggaggcct aaccatggac cgctaaatcc ctcttatccc ctattgtccc taatcgcctc
    17401 tgacatctac aaagacatcc taaaaggatt gctgattagc tacaacgata ctcgctttct
    17461 gcctaaatga ctctctgctg atgaacacag cctgatgcct ggtccctttg ttgatgtcat
    17521 tgttgctgac gcttctgtta aaggcattgg tcatcagtta atactcgagc tattagaagc
    17581 tatgctagtt atcgccaata agcaaagcct cacttaataa ctcactcata tagtcccctt
    17641 atcgtggaca gtgacataac aaacagtcac tagaaaccat gaggggcttt tatctggtcc
    17701 aaaaatatga aagaaaatcc taaaatacca agatgaaaaa caagcatcct tagccaagat
    17761 actctaaaga attgaagagc caaattaccc aagatggata gatgatgcca aaccagacag
    17821 aacgcttata tctagttcgg caaataccaa caccttccaa agaaatacaa gagcctcgat
    17881 cctcttaaca tgaggaaaaa ggcccttgtt taatcattgg taacatcatt attcacttgt
    17941 ctcaaaggag acgttcacac gttcaatcac tgaggtgaga agcagagcct ccaaactcct
    18001 ccattacttc taatgaaatc aagcggttat gagtagctac ttttttaaac caataagctg
    18061 aagctttagg tcgtcgcact tgggtatgga tattattttc cacaaggcca tagcggtttt
    18121 tataggcatt gagccaagac cagccatcaa ttggcgtcca tacatggtat ccaaaacaat
    18181 tcgagcctgc ttctattcct ttgtggaggt aggtcaaatg ttctttcaaa aatcggatgc
    18241 gataatcatc ttgaatctga ccagtttcat cacggtaacg gtcttctcct gaaatcccta
    18301 caccattttc agataagaac caaggaatat tgtcgtaatg gtctcgcatc ttgatggcaa
    18361 tatcatagac agcctcagga tagatttccc accccttatc cacgttcatg cggcggccag
    18421 gcatcaggta ggcgtcataa taccattcag gactccaaga tgggctaatc actggaatga
    18481 catccggagc cttcacgcgc ttagggtggt aaaaattcaa tcccaaataa tccactctat
    18541 tctcagcaat aagagccaat tcttctggcg ttgactgcca caaaacccca tcttttttca
    18601 ataccgcaac caattcttct gggaatttcc catgaacagc agcttccata aacaagtcat
    18661 tgttccaaag ttctgcaaaa tgcgcagcag ccatgtccgc ttctgattga ctagctgggt
    18721 aggctggcgt cagattgaga atggttccaa tacgcccatc actaagttct gctggacctt
    18781 gcctgtaagc ttgaataacc ttggctgtgg ctagggctag gttataggcg acctggactg
    18841 cttttttccc atccacgata gcagggtaat gaaattgcat taaataagag ccttccacaa
    18901 cgaccatagg ttcattgtgg acaaaccaat ccttaacccg atcaccaaac tgctcaaaac
    18961 aaaccttgct aaaggcgaca aataagtcca cgacatgctt tgattcccag ccaccatagg
    19021 cttgatagag ggcaatgggc aggtcaaaat gatgcaaatt aatgacagga cgaataccat
    19081 tggccaagca agcatcaatc actcgattat aataagcaag gccatcagga ttaatcgtca
    19141 cttgctcaaa gtcatcaatc aaacgcgtcc actgaatgga ggtgcggtag gaattgtgac
    19201 ctagtgaagc taacaaggcc aaatcagatt caatctgatg ataggcatcc gaagccgtat
    19261 caggtcccac gtaatcgtaa aacaagtcag gctcctcttc ataccaataa tcaaagagat
    19321 tgcggtgctg tttagcaaat cgcccctcac tttgagggcc tgaagtggct cctccccacc
    19381 aaaactcttt tggaaatgct aacatatcat tcctttctag ctcgtatgac taagcataat
    19441 cttcaggtct tgcttgggta acttgacctt gattagctgt tagtttatct tgctgttgat
    19501 agtagatgcg atagtagcga cttggaatgt cacttccaat acggtgttta tcttcttgta
    19561 agtcagcata gagtgtttcc aaatgaggcc cctgctctaa aatggcctgc caaaaatctt
    19621 ggtctttggc cacacgttca aaccaaggaa caatagcttg ttgaaacgct ggcttatcta
    19681 gctttctcaa cgtattgaca cgttctacca attcatctac ccaagctgat aacgttgata
    19741 catccttagc caggagagct tcttccactt caaaaggaag gtccctgtgc agatgacgat
    19801 tgccattatg ccaagcaaat gcctgtaaag ctaaggctaa ttcagcatct cctgtatagt
    19861 ctgttaaggt ttctagccaa gagttactag gctgataacg gttagcatcc cacagataat
    19921 ggctcatgtc tgtcaaggtc agcttagata attcccaact aatcataggg ttagaaacaa
    19981 tccccttgac ctgatagtct gattggcata aaaatggtga gcgattagca aaaggggtta
    20041 aaaagagacg ttctggatct ttttgataat cattaacagg aatattgtcc caaataatga
    20101 taggccgctg atatactgct gccatggttt cgatatctgc ttgcgagatt tgactcgcta
    20161 gcgtgcttgg gcctgtccag aaaaaggcga cttctttagg aatcctttct gacagctctt
    20221 gcaaatagat agaatcatgg tggttgtcgt attctgtcgg acagatcacc aattctggcg
    20281 ccgcatgttg ttggtttaaa aagtgatgaa cctcagttgc caagtgggcc tgggcatagg
    20341 cagtcttttt gaatcgtctc tcaacagcat ctacaatttg gtagtcaata tcatccagca
    20401 aaagcccaaa atgacaaaca cctaacgcta gaagttgttg caatttttga tagagcaact
    20461 gatagtcagc ttccttggta taatcaaaat caagtcccgg actaatcata taccaaaaat
    20521 caatcccttc ttccttggct actgcaagta gctctttgaa ataagtcacc caatcctcag
    20581 gataaagatc gcgccacagt tttcgctggt aatcatcatc tttcggagca tacatgtaag
    20641 tattcatcct tttacgtcca atgaaacgca ggcaatctaa ccgctcttct cgtgtccacg
    20701 gtgttccgta aaagccttca attatccccc gcatagcaaa agaaggacta tgcttgacag
    20761 atacaatcgg taaataaagt ttatcccctt tgaaagtcat cactttaagc aaagcttctt
    20821 gggcgtaacg aaaacctcta aggttttggc tttcaataat aatttcctta tcttctgaaa
    20881 ccttcagggt aaaggcatcc ttatccagct gacggttaaa gaaatgttta acggtcaact
    20941 ctgcttggcc ttcttcaatc cactgaaaat actttgacgt tgccaattct gccagtaggg
    21001 ctttttgatt ttcaaaacgg aaaaaacggc caataaagcg gcatgtcaac ggcatgtcaa
    21061 agacaagata gtctcctctt gtcatgactt cttgataatc ctttaaggcg tgataaatgg
    21121 tcatttctgg tctcctttac ctgagctaac cagctcatgc tagtaacgtc ttttttagtg
    21181 actactttct ctgataaata cttgaacagg taactggcaa gacaccactg cttggtctgg
    21241 ctcatgaata atctgcaaca agactttagc tgcttcttgc cccatttggt aaaaatcttg
    21301 agctgctgtg cttaatttgg gactcaacaa acgggaggct tgactattat caaagcctac
    21361 aatagcgact tgatcaggaa tatataagcc tacctgtgtg attttttgaa tcagctgaat
    21421 agccaaccaa tcgttttcca cgacaagccc ccttttagtg gctgtcgtct ccgataaggt
    21481 tttcaccaga cggtccaaat aagcatctgt tgtttcagtc tctgtcttag gaaaataatg
    21541 ggattttaga gacgattctg ccattgccgc taagtaaccc aaataacggt ctctaacgga
    21601 tgatacttct ccaaaagagc ctgttgccac aaaactaatc tggtcacagc cttgctcaat
    21661 caagtgctga gtcaattgac aggcaccgcc tttattatcc gctacaacag acggaaactg
    21721 aaaaagatct agagatttat ccaacaagac tagaggaatg tgatgatggt cgcagtaaaa
    21781 caggaaatca atactgtgat tgacatcttc aggataataa ataatcccag catagtctga
    21841 cagggtgtct aaccttactg tactggccaa ttgaaccatg agacggtaac ctgtttcagc
    21901 aatggaggtc ataattccct tagcataatc tcccaattca taatcagaag taaaaggaag
    21961 aatcaacaat aaatccttat tcgcttcagg ggacgtcact tgcttttcag ctacgaagct
    22021 tcctttccca cgacttctcg taatcaagcc ttcttgctcc agttctacaa gcgctcgctt
    22081 agaagtaata cggctaaccg agaactgttc tgacaattct ttttcagtag gtaggcggtc
    22141 accaatttgc aaacgacctg atgctatctg ctctttaatg aaatgatata tctttttgta
    22201 taataatttt gtcattcttt actcccgtta tcagtatagc atgtcaaaaa agagttgtaa
    22261 accttttcaa aaacttatag acaaagttta acttatcatt tataatgaaa ccgaagataa
    22321 atgatatatc attttggagg atatgatatg acacgaccaa tcccaactag cgtcagccaa
    22381 tttatggcca aggtggaaag cctttgtgga gaccaacacc ctgattgggc tcttaatttc
    22441 aaaaccagct ttaccaatac cttagagaca accctaaaaa cctacgaaga tggcactagc
    22501 tttctcttga caggagatat tcctgccatg tggttacgtg attccactgc gcaaatgaaa
    22561 ccttacctct tcctcgccaa ggaagatgaa gaaattagaa agattattgc cggtttggtc
    22621 aaacgccaat tccgctacat ttgtatcgat ccctatgcca atgccttcaa cgaagaagct
    22681 aacggaaaag gacaccaaac agatcgtacc caaatgaacc cttggatttg ggaacgcaaa
    22741 tatgagattg attccctctg ctaccctatt cagctagctt acttgctcta tcgtgaaaca
    22801 ggaagcaccg atcagtttaa tgacgatttt catcgtgggg tagaactcat tcttgaccta
    22861 tggacagttg agcaagacca cgcccagtct ccttacttgt ttgaacgcga tacttggcgc
    22921 aaagaagata ccctaacaca tgctggaaaa ggaagtcctg tcgcaccaac agggatgacc
    22981 tggtcaggct ttagaccaag tgatgatgct tgtcaatatg gttacctcat tccttcaaat
    23041 atgtttgcag tggttgtgct ttcctatcta gaagatttat ataacaacct ttttcacaat
    23101 gaaccagtag ctactcgtgc caagcagctg aaagaagcta ttcaatcggg tattgcagac
    23161 catgcccttg ttcaaaacag caagggagaa accatttacg cttatgaagt ggatggtctg
    23221 ggacagtttt ccatcatgga tgatgctaat attccaagcc tccttgctgc accttacctt
    23281 ggtttttgcg ctaaagatga ccctatctat ctggcaacgc gccgcaccat tctcagccaa
    23341 gaaaatcctt attattatca gggaaatgca gcagcaggca tcggttcttc ccatacacca
    23401 gaaaattata tctggcatat cgcccttgcc ttacaaggat tgaccgctct tgaccaagac
    23461 agtaaaaaag agatgcttga tttgcttgtg gcaacagatg ctggtaccca cttaatgcac
    23521 gagggtttcg atgtcaatga tccttatcaa tacactcgtg agtggttctc ttgggctaac
    23581 atgatgtttt gtgaactact tcttgactat cttggcttta gcattactcc ttagaaagtg
    23641 aggccactat ggcaactaaa aaagtacata ttatttcaca cagtcactgg gatcgcgagt
    23701 ggtacatggc ttacgaacaa caccacatgc gtctgattaa cttaatagat gacctgttag
    23761 aagtttttca aacggatcct gattttcata gttttcattt ggatgggcaa accattatcc
    23821 tagatgatta tttgcaagta cgccccgaac gagaacctga gattagacaa gccattgctt
    23881 cgggaaaact ccgtatcgga cctttctata tcttacagga cgattttttg accagcagtg
    23941 aatccaatgt gcgcaatatg ctgattggta aggaagattg tgacagatgg ggcgctagtg
    24001 tgccacttgg ttattttcct gatacctttg gaaatatggg acaaacacca cagctgatgt
    24061 taaaagccgg cctacaagct gctgcctttg gtcgtggcat tcgtccaact ggatttaaca
    24121 atcaagtaga taccagtgaa aaatacagct cacaattctc tgaaatcagt tggcaaggcc
    24181 cagataacag tcgtattctt ggactcctct tcgccaactg gtacagcaat ggcaatgaga
    24241 tcccgacaac agaagctgag gcgcgtcttt tttgggataa aaaacttgct gacgccgaac
    24301 gctttgcctc aaccaagcac cttctgatga tgaacgggtg tgatcatcaa cccgtacaac
    24361 ttgatgtcac caaggcaatc gccttagcca accaactcta tcctgattac gaatttgtgc
    24421 attcctgctt tgaagattac ttgtctgatc tcgcaaatga tttaccagat aacctttcaa
    24481 ccgtccaagg agagattacc agtcaagaga cagatggctg gtatacccta gctaacacgg
    24541 cttctgctcg catttacctc aaacaggcta ataccagagt ctctcgtcaa ctcgaaaaca
    24601 tcaccgaacc cttagcagca atggcttatg aggtgacaag tacctaccct cacgaccaac
    24661 tgcgttacgc ttggaaaacc ctcacgcaaa atcaccctca tgattctatc tgtggttgta
    24721 gtgttgatag tgttcatcgg gaaatgataa accgttttga aaaagcctat gaagtcggac
    24781 actatttagc aaaagaagct gcccagcaaa ttgctggcgc agttaacacg agtgactttc
    24841 caacagatag ccaacctttc ctcttattta ataccagtgg ccattccaaa acaagtgtta
    24901 ctgagctcac cctgacctgg aaaaaatatt attttggcca acgctttcct aaagaggttt
    24961 accaagaagc tcaagagtat ttggcaggac tctcccaatc tttccaagtc attgatgtat
    25021 caggaaacac tatctcagaa gcagacattt tggacacaag catcgccttt gactacgatt
    25081 tgcccaagag aaccttccga gaaccttatt tcgccatcaa agtgagatta cggctaccaa
    25141 taactctccc tgccatgtct tggaaagcct tagcattaca actaggaaac gagacagctc
    25201 cttcagcaac ggtcccactc tacgacgata gtaatcagtg ccttgaaaat gagtttctaa
    25261 aagttatgat acaaaccgat ggccgtctaa ccatcaccga taaacagtca ggggtgagct
    25321 atcaagatct cctacggttt gaagattgtg gcgatattgg aaatgaatac atttcccgcc
    25381 aaccaactca tgaccaacct ttctatgcgg accaagggac caccaagctt aacatcatta
    25441 gcaacaccgc tcaagttgct gaacttgaaa tccagcaaac ctttgccatt cctatctccg
    25501 cagataagct cttacaggct gagatggaag ctgtcattga catcacagaa cgccaagcaa
    25561 gacgttcaca agaaaaggct gagctaacct taacaaccct tatccgtatg gagaaaaaca
    25621 atcctcgcct ccaatttacc acacgttttg ataaccaaat gacaaatcat cgcttgcgcg
    25681 tcctattccc aacgcacctt aaaacagacc atcatctagc tgacagtatt tttgaaactg
    25741 tcaaacgtcc aaatcatcca gatgccacct tttggaagaa tccaagtaac ccacagcacc
    25801 aagaatgctt tgtgagtctc tttgatggtg aaaatggagt cactattggt aactatggcc
    25861 tcaacgaata tgagatctta ccagatacca acaccattgc catcactctc ttacgttctg
    25921 ttggtgaaat gggcgactgg gggtatttcc ctactcctga agcccaatgc ctcggcaaac
    25981 acagcctatc ttatagtttt gaaagcatca ctaagcaaac acaatttgcc agctattggc
    26041 gggcacaaga aggccaagtt cctatcctag tcgaacaaac cagccatcat aagggaagct
    26101 taagagcaga gcatagctat gtcactgggg cagacgatca agtcgctcta acggctttca
    26161 aacgtcgctt agcagacaat gcccttatca cgcgcagcta caatctttca aacgataaaa
    26221 cttgtgactt tagcctaagc ctgccaaact acaatgctaa ggtcactaat ttgttagaaa
    26281 aagacagcaa gcaaagcaca cccagccaac ttggcaaagc tgaaatttta actctagctt
    26341 ggaagaaaca ataaactatt atcattagta atagattaac atattcaaaa agagtctggg
    26401 actattgtct cagactctta agttgatttt gagtgattat taataccttt aacatcagtc
    26461 aggcttagct atttctatta actgggttaa aatgccatca tgaatctgcg agctaattgt
    26521 gagatagtca taacgattta aaatggtcgt gacattcctt aagtcaaatt gccagtcatc
    26581 tctttttttc aaagccggtg tagcaaacac gctttgacta tcattttgtc cttgtttagt
    26641 actgctttga atgactatga caagtttatg gttttgatcc agaaatgcta ttgataagca
    26701 aggttgcttt gtctccaaac tcatttctat agcattatct aacaaaaatg acaatagctt
    26761 agtgaaatct actacttcta gaaaaaacgt tgcaatacaa ttaggaatcg atacctcaac
    26821 cttaagcttc ttattttttg cctcaattaa tttagctaaa acaatatgtc tgattgcttc
    26881 aacttgtaat ttatctaaac aagttaaatc aagtctgtca tctttagcat tattcttttc
    26941 agcattcaag ataccttcat aagtaagtct cacaatagag atatcatttt gttcgattcc
    27001 aatcttaaga cgactggaca cggtagttaa tagctgccta agctcttgaa tatcttgata
    27061 cagcaatcca aggtgctgac tataattaat cagctcacga tattcttttt gttgcacaat
    27121 tgcctcaata gagttttgtt ttacataacg ctctaaatga attaataaag taagaaacaa
    27181 aatgaaataa aagagcacta tgattgaacg agcagtcgtt gtagcaagtc ctgataaaga
    27241 aggcgacatc acatctatcc cttggacaca caagtaatat agagccatcg aagagttagt
    27301 aaacactaat agtttactag ctctatgtga ttgaaaatat tggcgccagg ttgaaaaatc
    27361 gaaatgaaaa acttgaatgc agcgataaat caaaaaaata ctaaagcaag taatgctgta
    27421 aatcagtagt gtattatgtt taacaactga ataaggcata ccaaacaatg gcataacaaa
    27481 aaatacaata aatcgcttaa ccaaactaat agacactagt ggaaaaaagg cataaaacat
    27541 taaaaactta gcttttattg atttaccata gtatagggct ataagcgcaa agaaaagaaa
    27601 ctgagccaac atcacaacat caagaatgaa atggtctgga aagaaagccc aaaaaactac
    27661 ttgaaacaaa accatactaa gtgataaata aaaaatattt ttcaggcgaa gcggaattgc
    27721 acttacaaag cta
//
LOCUS       DATWVB010000019        26742 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.019, whole genome shotgun sequence.
ACCESSION   DATWVB010000019 DATWVB010000000
VERSION     DATWVB010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26742
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.019"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            523..741
                     /locus_tag="VCX65_000988"
     CDS             523..741
                     /locus_tag="VCX65_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5053455.1"
                     /translation="MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADV
                     LVQFSKLYNVSIDYLLGQTDYPYRFHNK"
     gene            complement(812..955)
                     /locus_tag="VCX65_000989"
     CDS             complement(812..955)
                     /locus_tag="VCX65_000989"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053456.1"
                     /translation="MGISPTGLLRWQPERSEVSLSLFVVMADREPLYFIANNYRSYHG
                     VSH"
     gene            1042..1262
                     /locus_tag="VCX65_000990"
                     /pseudo
     CDS             1042..1262
                     /locus_tag="VCX65_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903600.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            1964..2347
                     /locus_tag="VCX65_000991"
     CDS             1964..2347
                     /locus_tag="VCX65_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEP5053457.1"
                     /translation="MKVHTTLEKDENGNWYRKDQTKTPAGERLIELDDVTIVVLENWR
                     RNQVVNTDTDFIISRFGEPFCKSTICRVIKHKAQEVGVPVITGKGLRHSHASYLINVL
                     KKDILYVAKCMGHADKSTTLNTYSH"
     gene            2610..3845
                     /locus_tag="VCX65_000992"
     CDS             2610..3845
                     /locus_tag="VCX65_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEP5053458.1"
                     /translation="MIKRWVILFFMVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSELHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDNRYPGSALEEENTLSAQDVAVVTMHLLEDFPEILEITKQTEVNFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRVITVILNADGSDKN
                     QNTRFEQANRLLDYVDRTYCRRKILKKGSLVLERSLPIQDGQVKELPVSVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(3961..4923)
                     /locus_tag="VCX65_000993"
     CDS             complement(3961..4923)
                     /locus_tag="VCX65_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEP5053459.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSQFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMFPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEIGSAANLTLKQMKEMKQFGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            5256..6533
                     /locus_tag="VCX65_000994"
     CDS             5256..6533
                     /locus_tag="VCX65_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEP5053460.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYP
                     RLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTGFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRQYWKKHIEKNVLLTH"
     gene            6568..7152
                     /gene="folE"
                     /locus_tag="VCX65_000995"
     CDS             6568..7152
                     /gene="folE"
                     /locus_tag="VCX65_000995"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEP5053461.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            7161..7961
                     /gene="folP"
                     /locus_tag="VCX65_000996"
     CDS             7161..7961
                     /gene="folP"
                     /locus_tag="VCX65_000996"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEP5053462.1"
                     /translation="MKIGKFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWVDPGFGFAKSVQQNTELLKGLDRVCHLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            7968..8327
                     /gene="folB"
                     /locus_tag="VCX65_000997"
     CDS             7968..8327
                     /gene="folB"
                     /locus_tag="VCX65_000997"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEP5053463.1"
                     /translation="MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            8324..8824
                     /gene="folK"
                     /locus_tag="VCX65_000998"
     CDS             8324..8824
                     /gene="folK"
                     /locus_tag="VCX65_000998"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEP5053464.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEFYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            8974..9861
                     /gene="murB"
                     /locus_tag="VCX65_000999"
     CDS             8974..9861
                     /gene="murB"
                     /locus_tag="VCX65_000999"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEP5053465.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTSSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHAGFMINVVDGTAKDYEDLIAYVIETV
                     ENHSGVRLEPEVRIIGENL"
     gene            9907..11061
                     /locus_tag="VCX65_001000"
     CDS             9907..11061
                     /locus_tag="VCX65_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053466.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWVFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL"
     gene            11045..11839
                     /locus_tag="VCX65_001001"
     CDS             11045..11839
                     /locus_tag="VCX65_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053467.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            11836..12612
                     /locus_tag="VCX65_001002"
     CDS             11836..12612
                     /locus_tag="VCX65_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053468.1"
                     /translation="MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            12605..13678
                     /locus_tag="VCX65_001003"
     CDS             12605..13678
                     /locus_tag="VCX65_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEP5053469.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDDIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(13733..14398)
                     /locus_tag="VCX65_001004"
     CDS             complement(13733..14398)
                     /locus_tag="VCX65_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEP5053470.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKWRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQLLEKGLSEST
                     FQWIIENIKAFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(14379..15920)
                     /locus_tag="VCX65_001005"
     CDS             complement(14379..15920)
                     /locus_tag="VCX65_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP5053471.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTRPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLFLCLLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKTGILQLCNQAGQELIARKCQLGKPTGNSFNHLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSVTKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGWQH
                     ERFNH"
     gene            16081..17412
                     /locus_tag="VCX65_001006"
     CDS             16081..17412
                     /locus_tag="VCX65_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEP5053472.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLPVYLVLATLILITG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHPSYSGQGQLVKIGHSEDMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTGFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKEVVATLSWQYFIVVISVVLTVVSVGFFVSRFLNMNPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            17444..18610
                     /locus_tag="VCX65_001007"
     CDS             17444..18610
                     /locus_tag="VCX65_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEP5053473.1"
                     /translation="MKNQLGQLALEQAKTFGGKLEVQPKVDITNKHDLSIAYTPGVAG
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALAPTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLQKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEADQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYPDEALEAGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPGDALSTTNIIPDAFKEGVAEIVAKSVRSVVLKS"
     gene            complement(18692..19630)
                     /locus_tag="VCX65_001008"
     CDS             complement(18692..19630)
                     /locus_tag="VCX65_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent alcohol dehydrogenase"
                     /protein_id="HEP5053474.1"
                     /translation="MKAATYLSTGNLQLIDKPKPVIIKPTYRPVGKNHSICGTDLHIL
                     GGDVPACKEGTILGPEGIGIVKEIGDAVTNFKIGDKVIISCVTSCHTCYYCKRGLSSH
                     CEDGGWILGHLINGTQAEYVHIPHADGSLYHAPDTIDDEALVMLSDILPTSYEIGVLP
                     SHVKPGDNVCIVGAGPVGLAALLTVQLFSPANIIMVDLSQNRLEAAKTFGATHTICSG
                     SSEEVKAIIDDITNGRGVDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFNL
                     DELWIKNITLNTGLVNANTTEMLLNVLKVIIDNDIS"
     gene            19866..20597
                     /gene="aphA"
                     /locus_tag="VCX65_001009"
     CDS             19866..20597
                     /gene="aphA"
                     /locus_tag="VCX65_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HEP5053475.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            20775..22307
                     /locus_tag="VCX65_001010"
     CDS             20775..22307
                     /locus_tag="VCX65_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEP5053476.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVMVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGNWLHLPAYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            22470..23084
                     /locus_tag="VCX65_001011"
     CDS             22470..23084
                     /locus_tag="VCX65_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEP5053477.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     IEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIQAYI"
     gene            23243..24391
                     /locus_tag="VCX65_001012"
     CDS             23243..24391
                     /locus_tag="VCX65_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEP5053478.1"
                     /translation="MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYK
                     TSLPFFYGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITW
                     IISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYS
                     QQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTG
                     KYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGVLVAFTA
                     LIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAM
                     WVLMAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQAIQKKQVS"
     gene            24440..25120
                     /gene="radC"
                     /locus_tag="VCX65_001013"
     CDS             24440..25120
                     /gene="radC"
                     /locus_tag="VCX65_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEP5053479.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIFEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(25122..25817)
                     /locus_tag="VCX65_001014"
     CDS             complement(25122..25817)
                     /locus_tag="VCX65_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEP5053480.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVDPKYYQEEKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTIAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(25827..26471)
                     /locus_tag="VCX65_001015"
     CDS             complement(25827..26471)
                     /locus_tag="VCX65_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEP5053481.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
BASE COUNT         8180 a         4448 c         5525 g         8589 t
ORIGIN      
        1 tacttatttt gaatagttta atttatatca tttttgccta tgtaacctat ctgatcaatc
       61 atattattag ctatatattt agtacaggtg tggcattagg tatttcaatg gtaggtgtta
      121 ttgttgcagc tttttgtgaa acgagccttg gtgataaggt atggtttctt attccatggg
      181 catggctttt aagaatatca gatactctat ataaccaaca gaaaatggca attgttccac
      241 ttattgttat attttttgtt tcatgcacag tagctttact tcatatacga atatttaaaa
      301 gttggaatca agactgtttg acaagtagtt aaatacatct attttgttta cctaacaata
      361 aatatgattt ttaagttata aatactatct aacttgttta actaaaaaat gactataaaa
      421 tttcaatggt ttactagctt atatttaata gacttgtcca aataggacaa ttaaacattt
      481 tttaatcaaa tctcctttat actgatattc ggagaatgtt agatgtatcc gcgtattagg
      541 aatttgagag aagataacga tttcactcaa aagtttgttg caaatttact ttccttctct
      601 catgcaaatt atgcaaaaat tgagagagga gaggttgcct taatggcaga tgttcttgtg
      661 cagttttcta aactctataa cgtcagtatt gattatttat tagggcaaac agattatccg
      721 tatcgttttc ataataaata aaagtctcgc cttgatttgt tcattgacaa ctgaataaac
      781 cgaggtggga ctttcttgtt tgtcgagcaa tttagtgaga tacgccgtga taggagcgat
      841 aattattagc tataaaatag agtggttctc tatctgccat gaccacaaat agggacaatg
      901 atacttctga acgttcaggc tgccagcgta aaaggccagt gggtgagatt cccatgagtg
      961 atttaaccag tcatacccac ggaggttgta atttttttga aaggagtgga ggtgtgaaaa
     1021 tagtaacata taaaaagctt gatgaatatt ggttttctcg aacatactgc aagaaatatt
     1081 attagagaag caaaaagaat agctataaaa aagttgaaga agctcgcgaa cttgaacaaa
     1141 atgcggtaca attaagtaaa tcgccctttg acaatagaag acttggtatt gctcctaaag
     1201 atattgtaga agagttagta ggtgttctac tctctgaaga aagtttagaa agtgagaatt
     1261 aaagatgact ataaaaaatc aaaaaaagta caaaggtgtt tattgtgata agaatgggaa
     1321 gatattttat caagctgatc ttggtgtaga tccagtaaca ggtaaacgag ttcaaaagaa
     1381 agccagaaag aattagtatg gaaagccatt tggtacaatg aaagaagcgt atgatgaact
     1441 ggttcggatt aggtatgagt tcagtaataa tcttagtatt gaaaatgaca atatatcgtt
     1501 tgaaaactat atgaatacta tttacctaag agcatataag caaaaggttc aggctgtaac
     1561 ttatgaaata gccttaccac atcataagtt atttattcag tattttggtt ctaaactttt
     1621 aaagggaata acagcttgag attgtgaatc ttttagttta catattattg aaaattatgc
     1681 aaagaattta tggtcgcgat tcaaagcttg catggggtat gctgaaaggt tagactatat
     1741 ttcaaaagtg ccatgtaagg ctttggataa tcctaaaggg aaacatcccg acactccatt
     1801 ttggacttat attgagtttc agaattttat aaaatcgttt gatttgcaag attatgaaga
     1861 gctacaaaga tttacaacta tttggctata ttatatgaca ggtgttcgtg taagtgaagg
     1921 tttatcatta tgatgggaaa atatcgattt cgaacaaaaa ttcttgaaag ttcatacaac
     1981 cttggaaaag gatgaaaatg gaaattggta tcgtaaagac caaacaaaaa cgccagcagg
     2041 agaacgtctt attgagttag atgatgtgac aatagtagta ttggaaaatt ggagaagaaa
     2101 tcaagtagtc aatactgaca cagatttcat tatttcacgg tttggtgaac cattttgtaa
     2161 atcaacgatt tgtcgagtta ttaagcacaa agctcaagaa gtaggagtac cagtgataac
     2221 gggaaaaggc ttgcgacata gtcatgcttc ctatcttatt aatgttttga aaaaagacat
     2281 tctgtacgtt gcaaagtgta tgggacatgc tgataagtct acaactttga atacatatag
     2341 tcactgattt aacgcattag ataaaacagt atctgaagaa ataacccaaa atgtaataag
     2401 ttcaggatta gattccattt tataccaaaa ttcctgccaa acaactaatt gatataacga
     2461 agcttattat atcgcccata taacaggatg tgttattgtt acagggtact tgctttatga
     2521 gcttgtttaa gctactaaag gtgggtgcca ctatacttcc ttccaaattt ctgagaattt
     2581 ttgctataat agtaactatg aaagatataa tgataaaaag gtgggttatc ctttttttta
     2641 tggtattaac ttgttcaggg tttggtaaaa cagttctcgc agctgatttt caagtgggag
     2701 cagaacatgc gattgtcgta gaggcagact ctgggagagt tctgtatgag aaagacgcta
     2761 agacgccaga tgctattgcc tctttgacca aattggtgac ggcttatctg gttttagata
     2821 aggttaaatc aggccagctg caattatcag atcaagttaa tctctcagat tatgcctttg
     2881 agttaacaaa agataggtct ttaagtaatg taccttttga caaaaaaact tattcagttc
     2941 aagacctgtt gacagctact ttggtagcaa gctcaaatag cgctgctatt gcgttagccg
     3001 aaaaagtggc gggctcagag cttcattttg taaatcaaat gagagaacag ctatctcatt
     3061 gggggattac ttctggtaaa atcctcaacg cctcaggtct gccaaatgag gtgttaaagg
     3121 acaatcgtta tcctggttct gcgttggaag aagaaaatac cttgagtgct caagatgttg
     3181 cagttgtgac gatgcatttg ttagaagatt ttcctgagat tttagagatc accaaacaaa
     3241 cagaagttaa ttttgctggc aattctatta aaagttttaa tcaactctta ccaggtatgg
     3301 ctaagggtag agcaggagtg gatggtttaa agactgggac aacagacttg gcaggtcatt
     3361 gtcttgtggt aacttctatt gaaaatggta tgcgagtgat taccgttatt ctaaatgccg
     3421 atggatctga taaaaaccaa aacacgcgat ttgagcaagc aaatcgtttg ttggactatg
     3481 tggatagaac ttattgtcgt cgtaagattc ttaaaaaagg aagtcttgtc ttggagcgat
     3541 cgctccctat tcaagatggc caagtaaaag aactaccggt atctgttgcc gaagatgtaa
     3601 ccatcatttt gcaacagggt gaacaagtcc ccaaacctaa acaatttatg atatcagaga
     3661 cttctttact agcaccgatt actaaaggtg aagtggttgc ttatttgacg tctccacgaa
     3721 taacagatca gtcagtgagg tatttaaagg aacctaagcg tattcctctt aaagctagcc
     3781 aatctcttaa aaaagcctct gacttacagc tgtggtggcg agattttctt gaaaaaagac
     3841 gttaaagata agaataaaat aattttaaaa caatcaaaaa agacagttat gaaagaattt
     3901 tttcataact gtctttttag tttacagtga gtatgatttg gaatgataaa aaaattgatg
     3961 ttatggttcc attgtttgta aaagattttc cggactcatg tttgggagga tacgaatccg
     4021 gttaagagaa agaagtccat tagccgcgct agctattcct tcgttagtgg taacacctaa
     4081 tttatagtta agtctagctg caatttgtaa ggtagtgtca ttatatctac cagatggata
     4141 agcaatggca atagtgtttt ggtttaattg cttatcaaga tagtcctttg aatctttcat
     4201 ttcagttgtt tgaacatcag gactagcctg ctctaaatca ggatgattca ctgtatgatc
     4261 ttggaaagac ataccgaatt gtttcatttc tttcatctgc ttaagagtca gattggcagc
     4321 gcttcctatt tcggttagtc ctgtaataac attattggta gctttagcat catatttttt
     4381 taagattggg taagcaacgt tgtagaaatc aatcatactg tcatcaaatg ttagccatac
     4441 aactttttta gcaggcaatt cattatttga aagagcgcgg tagacctctt caggactcaa
     4501 aaaatagtag ccctcgtctt tcattttttg aagttgttga tcaaagagat ctgggttgac
     4561 aatcaaatta gcattggccg tctcttcagg gaacattaca tgaatagcat gatacattaa
     4621 aatggggatc ttgacaggtg tttcttgctt ggtccaagtt aatttagaat gggccttttt
     4681 ttgagatttt gaggaatcga aatgagtctt cttaagtttt gtcgtttctt tttttgccgt
     4741 ctttttgtga tgaaaaagac ttattttagg tacaaattga gagacatctg acaagccgaa
     4801 tttgttagac ccttggtata aatagaaaat gagggtcaaa ccaagaatgc aggcaaataa
     4861 tagtataagg ttaatgagag tgaaggcttt tcttttttgg cgccgtttat gtctattgtt
     4921 cattacttgc tccttttttt gatataagta cctctattgt aacatttttt agagaaaaga
     4981 aggcttgaag tcagcctttt ttcttgtttt ttggaagaac gtgtattaag gagtaaaaaa
     5041 attgttgtca cagataacac tttaggaggt agcaaagact atgtggggct ggtattctta
     5101 tcacgtaaaa aaagcaatga agataaaagt gtagtgtact ttagaagtta tttgagtgtt
     5161 tggtgaggat aataaaaaaa aagggtacta ctctaggtta tctgctgtca ctttttttta
     5221 tatatggtat actaaagata gatgtgaggt atgaaatgac ttatgaagag actctagaat
     5281 ggattcatga tcacttagtt ttcggcatca agccaggctt aaaacgtatg ctttgggttc
     5341 ttggacagtt aggaaatccc caaaaaaatg tcaagggagt gcatatcgtt ggaactaacg
     5401 gaaaaggttc cacggtcaat catttacaac acatctttac gacagctggt tatgaagtgg
     5461 ggacctttac ctctccttat attatggatt tcaaagaacg tattagcata aatggtcgaa
     5521 tgatttcaga aaaagatttg gttattgctg ctaatcgtat tcgtcctttg acagagcgtc
     5581 tagttcaaga gactgatttt ggagaggtaa ctgaatttga agtgattact ttgatcatgt
     5641 tcctctattt tggagacatg catcctgtag atattgctat tattgaagca ggccttggcg
     5701 gtctttatga ttcgaccaat gtttttcaag caatggttgt ggtctgtccc tcaattggtt
     5761 tagatcacca agctattttg ggagagactt acgctgatat tgccgcccaa aaagctggtg
     5821 ttttagaagg gggcgagacc cttgtttttg ccgttgaaaa cccgtcagct cgagaggttt
     5881 ttttaacaaa agctgagcag gttggtgctt caatctggga atggcaagag cagtttcaaa
     5941 tggctgagaa cgcatctggc tatcgtttta ctagtccttt aggagttatt tcagatattc
     6001 acatcgctat gccaggacac caccaagtgt ctaatgcagc tttagctatt atgacttgct
     6061 taaccttgaa agaccgctat cctaggctaa cttcagatca tataagggaa ggtctggcaa
     6121 atagtttgtg gctaggccgt accgaattat tagcaccaaa tctaatgatt gatggggctc
     6181 ataacaatga aagcgttgct gctttggtag ccgtcttaaa aaataactac aatgataaaa
     6241 agcttcatat tttgtttggt gcgatcgaca ccaagcctat tgcggatatg ttggttgctc
     6301 ttgagcaaat aggtgacttg caggttactg gctttcatta ccctaacgcc tatccattgg
     6361 aaaaataccc agaacgtttt ggtagggttg ctgatttcaa agatttcttg gccctgcgta
     6421 agcatgccaa agcagatgac tttttcgtga ttacagggtc gctatatttt atttcagaaa
     6481 ttagacagta ttggaaaaaa catattgaaa aaaacgttct tttaacccat taaaaaagag
     6541 aaaatgaaaa ggaaaaggaa aaaactaatg aaaagggaaa gactaatgtc tattaataag
     6601 gaaaaagcag aagcagccat ttatcagttt ttagaggcta ttggtgaaaa tccaaatcgg
     6661 gaaggtcttc ttgacacgcc taaacgggtt gctaaaatgt atgcggagat gtttttggga
     6721 ctgggaaaag atcctaaaga ggagtttacg gctgtcttta aagaacaaca tgaggatgtg
     6781 gtgattgtca aagacattag tttttattct atatgtgaac accacttagt tcctttttat
     6841 ggcaaggctc atatcgctta cttgccaagt gatggtcgag taacaggttt gagtaaatta
     6901 gcgcgagcag ttgaagtagc tagtaaacga cctcaactcc aagagcgttt gacctctcaa
     6961 atagcggatg ctttagttga agccctcaat cctaaaggga ctttagttat ggtagaagca
     7021 gagcacatgt gcatgaccat gcgaggcatc aaaaagccag gtagtaaaac cattaccacc
     7081 actgccagag gcttatataa ggaaagtcgt gctgagaggc aagaagttat ttctctaatg
     7141 acaaaagatt aggagaactt atgaaaattg gaaagtttgt gattgagggc aatgcggcta
     7201 tcatggggat tttaaatgtg actccagatt ctttttcaga tggggggtct tacactactg
     7261 tgcaaaaagc attagatcac gttgagcaaa tgattgctga tggggctaaa atcatcgacg
     7321 ttggtggaga atcaacacgt ccaggttgcc aatttgtaag cgctaccgat gaaattgacc
     7381 gggtggttcc tgtgatcaag gccatcaaag aaaactatga tattctaatc agcattgata
     7441 cctataaaac cgaaacagct agagcagctt tagaggcggg tgccgatatt ctcaatgatg
     7501 tttgggcagg tttgtacgac ggtcaaatgt ttgccttagc agccgagtac gatgcgccta
     7561 tcatcttgat gcataaccaa gacgaagaag tttatcaaga ggtaacacaa gacgtttgtg
     7621 attttctagg caatagagca caagcagctc ttgatgctgg cgtgccaaaa aacaatattt
     7681 gggttgatcc aggatttgga tttgccaaat ctgttcaaca gaatacggag ttattaaaag
     7741 gattggaccg cgtctgtcat ttgggctatc ctgtcttgtt tggtatttcg agaaagcgtg
     7801 tcgtagatgc cttgttaggc ggaaacacca aagctaaaga gcgagacgga gcgacagcag
     7861 ccttgtctgc ttatgccctt ggaaaaggct gtcagattgt acgcgtacac gatgtcaagg
     7921 ctaatcaaga cattgtggct gtgttgagcc agttgatgtg aggacttatg gataaaatcg
     7981 tattagaagg ttgccgtttt tatggctacc atggagcctt taaagaagaa cagacccttg
     8041 ggcaaatttt tctggttgat ttagaattgt cagtcgattt gcaagcagct tctttgtcag
     8101 accaattaac agatacggtc cattacggga tggtgtttga tagtgtccgt cagttagtgg
     8161 aaggggaaaa gtttattttg attgaacgtt tagcaggtgc gatttgtgaa cagcttttta
     8221 acgaatttcc gcctattgaa gccatcaaag tggccattaa aaaggaaaac ccaccgattg
     8281 caggccacta taaggcagtt ggtattgaat tggagagaca gagatgacca ttgtttattt
     8341 aagtttaggc accaatatgg gggaccgagc agcttacttg caaaaagctc ttgaggcttt
     8401 agctgactta cctcaaacac ggttgcttgc tcaatcatcc atttatgaaa cgactgcttg
     8461 gggcaagaca ggccaggctg attttctcaa tatggcctgt caattagata cacaattaac
     8521 cgcggctgat ttcttaaaag aaacacaagc tattgagcaa tctcttggtc gtgtgaggca
     8581 tgaaaaatgg ggatcaagaa ctattgacat tgatatcttg ctatttggag aagagtttta
     8641 tgacacaaag gaattgaaag tgccacaccc ttatatgact gagcgtgctt ttgttttaat
     8701 ccccttattg gaattgcagc cagatttaaa attgcctcct aatcataagt ttttaaggga
     8761 ttatcttgca gctttagatc aatcagatat cacgctcttt tcagctcaac agacagagtt
     8821 ctagactctg ttttcggagt aatgcctgct ataagccaat ccataaagtt ttgccaaatt
     8881 catcgttatt ttttctaaaa tttgatataa tagtatcggc tttatgccga tttttttacg
     8941 cgtataagaa gtgataaaag aaagaagata actatgataa ctgaacttca tgggattgat
     9001 attcgagaga atgaacccct aaaacattac acttacacta aggtaggtgg cccagcagat
     9061 ttcttggctt ttcctagaaa tcactacgag ctatcacgca tcgttgctta tgccaacaaa
     9121 gaaaatatgc cttggcttgt tttgggaaat gccagcaatc tcattgtgcg agatggtggt
     9181 attcgtggct ttgtcatcat gtttgataag ctaaatgcag tgcacttaaa tggttatacc
     9241 ttagaagccg aagctggtgc caatctgatt gaaacaacga agattgccaa attccatagt
     9301 ttaacagggt ttgaatttgc atgtggcatt cctggaagca ttgggggtgc tgtttttatg
     9361 aatgcgggtg cctatggtgg ggaaatatca catattttct tatccgctaa ggtgcttacc
     9421 tcaagtggag agatcaaaac catttcagct agggatatgg cttttggtta ccgtcactct
     9481 gccattcaag aaacaggtga cattgtcatt tctgctaagt ttgctcttaa accgggtaat
     9541 tatgatacga tcagccaaga aatgaatcgg ttaaatcacc ttcgccaact aaaacaacct
     9601 ttagaatttc catcttgtgg atctgtgttt aagcgcccgc caggacactt tgcaggtcaa
     9661 ttaatcatgg aagcaaatct taaagggcat cggattggtg gtgtggaagt ttccgaaaaa
     9721 cacgctggtt ttatgattaa tgtggtagat ggcacagcta aagattatga agatttgatt
     9781 gcttatgtca ttgagacagt tgaaaaccat tctggtgtca ggcttgaacc agaagttcgg
     9841 attattgggg aaaacctgta accattattg ataattaaag aaagtaccgt ggaggattta
     9901 tgacaattga ctaagccaat tatcacattt aacaatgttt caaaaacatt tgaggacagt
     9961 ggaacacagg ttctaaagaa cattaacttt gaccttgaag aaggaaaatt ttacaccctg
    10021 cttggagctt ctggctctgg aaaatcaact attttaaata ttatggcggg cctactagat
    10081 gccagcagcg gagacattta tttagatggg gaacgtatta atgatttgcc gattaataaa
    10141 cgtgacattc ataccgtttt ccaaaattat gccctcttcc ctcatatgac tgtttttgag
    10201 aatgttgcct ttgctttgaa gctgaagaaa gtggacaaga aagagattgc taagcgcgtg
    10261 aaagaaacct tgaaaatggt tcaattagaa gggtatgaaa atcgttctat ccagaagtta
    10321 tctggtggtc aacgtcaacg tgttgccatt gcgcgtgcga ttatcaatca accgcgtgtg
    10381 gtcttacttg acgaaccact ctcagccctt gatttgaaat taagaacaga gatgcaatat
    10441 gaattacgtg aattgcaaca acgtctaggc attacctttg tttttgttac tcacgatcaa
    10501 gaagaagcct tggccatgag tgattgggtt tttgtcatga atgaaggtga aattgttcag
    10561 tcgggaacac cagtggatat ttatgatgag ccaattaatc attttgttgc taattttatt
    10621 ggagaatcta atattattaa cggtaccatg attgaagact atcttgtctc ctttaacggg
    10681 aaagaatttg aatctgtgga cggtgggatg cgccctaatg agcctgttga agtggttatt
    10741 cgtcctgaag atcttcaaat tactttgcca gaagaaggga aattacaagt taaggttgat
    10801 acccaattat tccgcggggt tcactacgaa attattgcct atgatgaatt gggtaatgaa
    10861 tggatgattc attctacccg caaagctatc gagggagaag ttatcggatt agactttacc
    10921 cctgaagatc ttcatatcat gcgtcttaat gagactgaag aggaatttga tgcccgtatt
    10981 gaagaatatg tggaaatgga tgagcctgaa gatggattga ttaatgccat tgaggaggag
    11041 cgtaatgaag aaaacctcta gtcttttttc gattccttac ttcttatgga ttctcttctt
    11101 tgttgtggca ccagtcactc tcttgtttta caagtccttt tttgacatag aagggcgcgt
    11161 gaccttagcc aattatgaaa ccttttttag ctcttggacc tatttgagaa tgagtgtgaa
    11221 ttctatttta tacgctggta ttatcacact cgtcacgctc ttgatttcat atcctacggc
    11281 tctcttttta acgcgcctaa agcacaagca gttgtggctt atgctcatta ttttgccaac
    11341 ttgggtaaac ttattgctaa aagcctatgc ctttatggga atctttggtc aacaaggagg
    11401 aattaacagc tttttaacct ttatggggat tggcccgcag caaatccttt tcacggattt
    11461 ctccttcatt tttgtagcct cttacattga gctccctttt atgatgttac cgatttttaa
    11521 cgctttggat gatattgacc ataatgtcat taatgccagt cgcgacctag gagctagtga
    11581 atttcaggcc ttctcaaaag ttatttttcc cctttcttta aatggggtta gggcaggtgt
    11641 tcagtctgtc tttatcccaa gtttgagtct ctttatgtta acccgtttga ttggtggaaa
    11701 ccgcgtgatt acacttggta cagccattga acaacatttt ttgaccaccc aaaactgggg
    11761 aatgggatca accataggtg tggtgttaat cttaaccatg gttgctatta tgtggctcac
    11821 aaaggagaaa agtaaatgaa aaaatttgcc aatctttatt tagcgagtgt ctttgtttta
    11881 ctctacattc ctatttttta tttgattttc tattctttca acaaaggtgg ggatatgaat
    11941 ggttttacag gatttaccct tgagcattac caaaccatgt ttgaggatag tcgtctcatg
    12001 acaatcttac tgcaaacctt tgttcttgct tttagtagcg ctctactagc aacgattatt
    12061 gggacctttg gagctatctt tatccaccat gttagaggta agtaccaaaa tgccatgcta
    12121 tcagccaata atgtcttgat ggtatcacca gatgtcatga ttggggcttc ctttttaatt
    12181 ctttttacat cattgaagtt tcagctgggc atgtcttcag ttttattaag tcatattgct
    12241 ttttcgattc ctattgtggt tttgatggta ttgccgcgct tgaaagagat gaatcaagac
    12301 atggtcaacg ccgcttatga tttgggagct aattatttcc aaatgctcaa agaagtcatg
    12361 ctgccatact taacaccagg gattattgca ggttatttta tggcctttac ctattcctta
    12421 gatgattttg cagtgacttt ctttttgact ggaaatggtt ttactacttt atctgttgag
    12481 atttattcgc gggctcgtca gggaatttcc ttggatatca atgctttgtc aaccatcgtt
    12541 ttctttttct ccatcctctt agtgatcggt tattattata tgtcacagga caaggaggaa
    12601 aaacatgcgt aaactttatt cctttctagc aggagttttg ggtgttattg ttattttaac
    12661 aagcctttct ttcatcttgc agaaaaaatc gggttctggt agtcaatcgg ataaattagt
    12721 tatttataac tggggagatt acattgatcc agctttgctc aaaaaattca ccaaagaaac
    12781 gggcattgaa gtgcagtatg aaactttcga ttctaatgaa gccatgtaca ctaaaatcaa
    12841 gcagggcgga accacttacg acattgctgt tcctagtgat tacaccattg ataaaatgat
    12901 caaagaaaac ctactcaata agcttgataa gtcaaaatta gttggcatgg ataatatcgg
    12961 taaagaattt ttagggaaaa gctttgaccc acaaaacgac tattctttgc cttatttctg
    13021 gggaaccgtt gggattgttt ataatgatca attagttgat aaggcaccta tgcactggga
    13081 agatctgtgg cgtccagaat ataaaaatag tattatgctg attgatggag cgcgtgaaat
    13141 gctaggggtt ggtttaacaa cttttggtta tagtgtgaat tctaaaaatc tagagcagtt
    13201 gcaggcagcc gagagaaaac tgcagcagtt gacgccgaat gttaaagcta ttgtagcaga
    13261 tgagatgaaa ggctacatga ttcaaggtga cgctgctatt ggaattacct tttctggtga
    13321 agccagtgag atgttagata gtaacgaaca ccttcactac atcgtgcctt cagaagggtc
    13381 taacctttgg tttgataatt tggtactacc aaaaaccatg aaacacgaaa aagaagcgta
    13441 tgcttttttg aactttatca atcgtcctga aaatgctgcg caaaatgctg catatattgg
    13501 ttatgcgaca ccaaataaaa aagctaaggc cttacttcca gatgagataa aaaatgatcc
    13561 tgctttttat ccaacagatg acattatcaa aaaattggaa gtttatgaca atttagggtc
    13621 aagatggttg gggatttata atgatttata cctccaattt aaaatgtatc gcaaataagc
    13681 actcaaaaag gctggtattt ctccagcctt tttaatgtat cgacagatga cgtcaccagt
    13741 acacgcgata gggacgacca accttggtaa aaatttgttg gctgttcagt tgcttatttt
    13801 cttctaaata agcaatgtat ttacggacag agacatggga taagtgacaa gcggaagcta
    13861 attcttggat agtaaaaggt tgatcaaagg ctttgatatt ttctataatc cactggaaag
    13921 tggattcaga taagcctttt tctaacaatt gtttgttttt agtgtctttt ttgctagtca
    13981 aacatttcag ttggtcaatt tgggcctgct ctagttgctg attggccaaa tgttctcgat
    14041 gcgtaacaaa ctgttggatg ctttcttgaa agcgttcaaa ggtaaagggc ttgatgaggt
    14101 agtcgataat tcctaaatga aaaccatctc ggataatatt cccatcattt gcggctgaaa
    14161 taataatgac ttcgcaagga atatgctgag cacgccattt ctccaaaaat tgaatcccat
    14221 tgccatctgt aatatgaata tccagtaaaa tgaggtcaat tgcgtaatca gtaagtatgc
    14281 tttgaacagc tttcatagag tcgctggata taatgcgatc aaaaagattt agtttttcga
    14341 ggtaattgcg atggataaaa tccaccatag gatcatcttc aatgattaaa acgttcatgt
    14401 tgccatccta cataaggtgt tgtcactgag aactgtaact cggttacggt ttgatgttga
    14461 tggaattggg aatttgtatc ggtcaagagc tgttgaaaat aaggtaagtc aaaaataggc
    14521 tgtacccgct ccaaatcaat ccaattgtct gtcaaggtgt aatggctgat taaatgattc
    14581 tgatcatgtt gaatactcaa aacgagtgat ttgggtctca gtgtggttag aagattagta
    14641 tggataaagc ggtaaatcat caaaccatta ttaagttgat tcttggtaac agaatgagga
    14701 atctcgctta aaacatcaat cttgagatgg acatttaatt cttggtattt ctcttgctct
    14761 ccaatgagaa aactagctag aagaggctcc ttaacaagga cagataagct agtgagaatt
    14821 tcattttcgg gctccaaaat actgtctaaa taaattttca attggtcata ataagcaata
    14881 tctactaagc cataaataac atgcaattga ttcatgaatt tatgagtttg ggcttgtaga
    14941 gcagaagcat aggcggtggt ataggctagc tgatccaagg tatcaatagc cttaactgct
    15001 tctcgcatga aaataatgtg gcctcggtga tcgtttttga cacagatggg tgaaatggct
    15061 aacaagtagt cttcctcacc ataccgaaag agttgttcat gcccctcttg caaactaagt
    15121 tttggaaaat caggaaagag gtgattgaaa ctgttgccag taggttttcc caactggcat
    15181 tttcgagcga ttaactcttg tccagcctga ttgcataatt gtaaaatacc agttttatct
    15241 accacaaata cggcggcttc gatttgatcc aacatggcat tacgctcttc aaagagctgg
    15301 taaatttcac ttggttctaa ctggtgcagt tgacgcttga gtcgaaaaga aataaaactg
    15361 gtgaccagta aactaataag aagacaaagg aataaagaca gggtataatt gcgttttgac
    15421 gttaaagcca catcatttag ggtagttagt ttaatgccaa ccgcaatagc accaatctgt
    15481 ttgtcaccgt caaacacagg tactagatag cgaagtgact ttcctaaagt gcccttggcg
    15541 gtagagataa ccttttttcc tgctagaaca gcctcctcat cacctccttg aaaaggtttt
    15601 ccgatatttt tcgggttagg acgggtgagt cgaatccctt tcatgttcat cacgaccaca
    15661 taatcaaggt tatagatgga ggcaatggag ttggtatagg ctgttgtttt agcatttggt
    15721 tggttgttta ggagtaattc tttaattgct tgatgacttg ctaacatttt tccagttgac
    15781 gttagcaaat gggtttcctg atttttgatg gattggtgcg tatcatgtag cataatcccg
    15841 taaaataggg aggttgtgac aacaatcata gataccaaaa tcaacgataa actggcccat
    15901 aaacgtagtg gttttttcat aaggtctcct ctttattgag tataacacga taagaaatga
    15961 cctgctagct taaattaatt aaataacttg aaaaaattaa agtagttaaa caacttaaat
    16021 aaactatgct tttgacatgt tctcttttat actagtctta tcactaaagg aggttgtttc
    16081 atggaaacaa taagcaagaa aatgcctcaa aaagacttgt ctgagcattc aaaagcatgg
    16141 caaaataggc gaataggctc cgttcccttg cctgtttatc tggttttagc taccttaatt
    16201 ttgatcacag gctggctcca acaattgcct gttaatatgc tgggtggctt tgctgttatt
    16261 ttaacccttg gttggctact aggaaccatt ggagcgacca ttccaggcct caaacatttt
    16321 ggtggcccag ctattttatc actcttagtc ccttcgattt tggttttttt taatctcctc
    16381 aaccccaatg tcttagaagc gacgaatgtc ttgatgaagc aagccaattt tctttatttt
    16441 tatattgcct gtctggtctg cggtagtatt ttaggcatga atcgaaaaat cttgattcaa
    16501 ggtctttttc ggatgattat tcccatgtta cttggaatgg tttgtgcaat gggtgtaggg
    16561 actttggttg gcgtcatttt aggattagac tggcaacata ccctctttta tgttgtgacg
    16621 ccagtccttg ctggaggaat tggtgaaggt attttaccct tatctcttgg ttacagtgcc
    16681 attacaggag tcggaagtga gcaattagtg gctcaactga ttccagccac cattattggg
    16741 aatttctttg ctatcttgtg cacggctttg ctcaatcgtt ttggagagaa gcacccaagt
    16801 tattctggtc aagggcaact ggttaaaatt ggtcacagcg aagacatgtc tgatgcccta
    16861 aaagacaatt ctggagccct agatgttaaa ttaatggggg caggcgtttt aacagcttgt
    16921 tcacttttta ttgctggtgg cttgttacag catttaacag gttttccagg accggtgttg
    16981 atgattattc tggcagcctt cttgaaatac ctgaatgtta ttccccaaga aacccaaaat
    17041 ggtgccaagc aactttataa atttatttcc agcaacttta cttttccgtt aatggcaggg
    17101 cttggactgc tttatatccc cttaaaagag gttgtggcaa cccttagctg gcaatatttt
    17161 attgtggtga ttagtgtggt gttaacggtt gtcagtgtcg gtttctttgt ctctcgcttc
    17221 cttaacatga accctgttga agcagctatt atttcagctt gtcaaagtgg tatgggtgga
    17281 acaggggacg tggctatttt gagtacggct gaccgcatga atctaatgcc gtttgcccaa
    17341 gtcgctactc gtctaggtgg ggctattacc gttatcacca tgacagctat tttaagaatt
    17401 atttttagtt aatccaaacc aataaaaaag agaggtattt cctatgaaaa atcaattagg
    17461 tcaacttgcc cttgaacaag ctaaaacgtt cggaggtaaa ttggaagttc aaccaaaagt
    17521 tgacattaca aataaacatg atttgagcat tgcctataca ccaggtgtag ctggtgtgtc
    17581 atctgccatc gcaaaagata aaacattagc atatgactta accaccaaga aaaatacagt
    17641 agccgttatc agtgatggta ctgcggttct tggtctgggg gatattggcc ctgaagcagc
    17701 catgccagtt atggaaggaa aagcagccct ttttaaagca tttgcaggtg tcgatgctat
    17761 tccgattgta ttagatacca aagatactga agaaattatt agtattgtca aggcgcttgc
    17821 accaaccttt ggtggtatta atttagagga tattagtgcg ccccgctgtt ttgaaattga
    17881 gcaacgctta attaaggaat gtcatattcc tgttttccat gacgatcagc atggaacagc
    17941 tattgtggtg ttagcagcca tctttaatag tttgaaactt cttcaaaaat cccttgatga
    18001 ggtatccatc gtggtgaacg gtggtggatc tgcgggatta tccattaccc gtaaattatt
    18061 agcagcaggt gctacgaaag tgacagtagt ggataaattt ggcattatca atgaacaaga
    18121 ggcagatcag ttagcaccac accatttgga tatagcgaaa gtcactaatc gtgagtttaa
    18181 atcaggtacc ttagaagatg ctcttgaagg agcagatatc ttcattggcg tatcagcacc
    18241 aggagtctta aaagcagagt ggattagtaa aatggcagcg cgcccagtaa tttttgccat
    18301 ggccaaccct attccagaga tttaccctga tgaagccctt gaagcggggg cttacattgt
    18361 aggtactggc cgtagtgatt ttcctaacca gattaataat gtccttgcct ttccaggtat
    18421 ttttagggga gcattagatg cacgggcaaa aaccattact gttgagatgc aaattgctgc
    18481 cgcaaaaggt attgccagtc ttgttccagg tgacgctttg agcactacta atattattcc
    18541 agatgccttt aaagaaggag ttgctgagat tgtcgctaaa agcgtcaggt cggtagtcct
    18601 taaatcatag aatatatgaa aaaaagagaa agttatactt taaatcacaa aataagtaga
    18661 agcatatttc tagcttctac ttattttgtg attagctaat atcattatca ataataactt
    18721 tcaagacatt tagtagcatt tcagttgtat tggcattaac aagtccagtg tttaaggtga
    18781 tatttttaat ccataattca tccaggttga aatcaactgg tttcccatga accccaacgt
    18841 tagcaatatg cccacctact gatataattt tttggcaaat atcaaatgtc gcgggataac
    18901 caacacactc catggaaata tcgacaccac gtccattggt tatatcgtca atgatagcct
    18961 tgacttcttc actacttcct gaacaaatcg tgtgtgtggc tccaaacgtt ttagctgctt
    19021 caaggcgatt ttgagataag tcgaccataa taatattggc tggagagaaa agttgaacgg
    19081 ttagtagggc tgcgagtcct actggaccgg caccaacaat acaaacatta tctccaggct
    19141 tgacatgtga tggcaagaca ccaatttcat atgaagttgg taaaatatca gaaagcatga
    19201 ccagtgcctc atcatcaatc gtatcaggag catgatagag actaccatct gcatgtggga
    19261 tatggacata ttctgcttgt gttccattaa ttaaatggcc aagaatccaa ccgccatctt
    19321 cacaatgtga cgaaaggcct cgtttacaat aataacaggt atgacatgat gtgacgcaag
    19381 aaataatcac tttatctccg attttaaagt tagtgaccgc atcaccgatc tccttaacaa
    19441 ttccaattcc ttcaggacca aggattgttc cttctttaca tgcgggaaca tccccaccta
    19501 agatatgcaa atcagttcca caaatagagt ggtttttacc aactggacga tatgtaggct
    19561 ttataatgac tggttttggt ttgtctatga gctgtagatt tccggttgaa aggtaagttg
    19621 ctgctttcat atttaactct ttataaggtt gagaggtaat caaccaattc atttttacac
    19681 agatattata atagtttaag aaagggtttt caatattttt taaatcgatt atgataattt
    19741 tttagatcat ctttgttgaa taacttcatc cttattcaga acttaaaggg cactattata
    19801 agaatttgaa accgctttac ttaaaccgtg tatttttgta caataatgat taaggaggtt
    19861 tttagatgaa aaaagaattt accagtatcc tgtttacagt tagtttttgt ggaatcatag
    19921 cattgcctgt cgaagctagt ggccctaaag ttccttatac acaagaaggt ataacggcca
    19981 tttcaaatca ggcaacagta aaattgattt ctattgctga tatcgcgagc agtttagaag
    20041 gacaaaaacc tataacggtt agttttgata tcgatgatac tttgttattt actagccaat
    20101 attttcagta cggcaaagaa tatataactc caggctcatt tgattttttg cataagcaaa
    20161 aattttggga cttagtcgct aaacggggag atcaggattc tattccaaaa gagtatgcaa
    20221 agcaactaat cgcaatgcat caaaaacgag gagataaaat tgtctttatt actggccgaa
    20281 ctcgaggatc gatgtataaa aaaggtgaga ttgataaaac agctaagtca ctggctaaag
    20341 attttaagtt agacaagcca atagctatca attatacagg agataaagct gtgaagccgt
    20401 atcagtatga taaaacatat tatataaaga aaaacggctc acaaattcat tacggagata
    20461 gtgatgaaga tataaatgct gccaaagagg caggtgcaag acctattcgc attttaagag
    20521 ctcctaattc aaccaatctt cctttgccaa aagctggagg atacggagaa gaggttttag
    20581 aaaattcggc ttattagtca aatatttgtg taagaaagga agtaacagta atttctttca
    20641 tcaccccact gagtaaccaa tagcccagtg ggttttttgg gttacagaaa tcagttctaa
    20701 aaaagaatca ctggtaactt aaggttgtct ttgatacaat ggtaacagtg tatttaaaag
    20761 aaagagagga taacatggaa aaccataaaa atgaattcac cttttccaac aaatcaatta
    20821 ttgcctatgt ttggcgtggt gttatggttg gtattattgc tggtgttatt gttagtttat
    20881 tccggttgtt aattgaagtg acagctgact gggtgattga atggtaccga tacgctcata
    20941 tcaattcgct gttgctactt cctatactaa gtgtcagttt gttagctgtt ctttttgtag
    21001 gttttttagt aaagtctgat tctgatataa aaggatcagg gatcccccat gtcgaaggag
    21061 aactaaaggg gctaatgtcc ccagattggt ggagtgtcct ttggaaaaaa tttttaggag
    21121 gaatcatggc tatttctatg ggatttatgc tcggtcgtga gggtccttcg attcagttag
    21181 gtgctatgtc agccaaagga ttagctaagt ttttaaaatc gagtcgtttg gaaaagcgag
    21241 tgctaattgc cagcggagca gcagcagggc tatcagcagc ttttaatgct ccaatagcag
    21301 gcctcttgtt tgttgttgaa gaaatttacc atcatttttc gcgtttaatt tggattacag
    21361 cgctagtggc tagcttagtg gctaatttta tttctctgaa tatttttgga ttgaaaccag
    21421 tcttagcaat gtcagaggcg atgccttttt tagggctaaa tcaatattgg ttgttgcttt
    21481 tacttggatt atttctaggc tgcttaggct atttatatga gatagttatc cttaatttta
    21541 ataaacttta tgttatttta gggaattggt tacatctgcc agcttatttt tacggtatta
    21601 ttatggtttt tctaatttta ccgattggct attatttacc acagttactt ggaggagggc
    21661 atggtttaat actttcttta tccaatcaac aattgccttt gatgactatc ttcttttatt
    21721 ttattattcg atttattgtt agtatgttta gttatggaag tggcttacct ggaggtattt
    21781 ttttacccat tttaacttta ggtgctttgg caggcctatt atttgggcaa atagcttctc
    21841 aattaggttt attgaaccaa tcttttcttt ctcttttttt gatattaggg atggcagggt
    21901 attttgcggc aatttcaaaa gcaccactga caggcatgat tttggtaact gaaatggtag
    21961 gtgatttgaa acccttaatg gccatagctg tagttacttt tgtctcctat ttagtgatgg
    22021 atttgttaaa tggacagcca atttacgaag ctatgctaga taagatggca atgaagcatc
    22081 caactaatct tgttgaacca acattaattg aattgactgt tggtgataag attgcaggga
    22141 aatatgttaa agagttaaag cttccagaaa atgtcttaat tacaacccaa attcaccatc
    22201 aaaaatctca agttgtgtca ggtaacacgc gccttttgtc aggagcaact atctttttgg
    22261 tcgttaatga agctgataca ggttttgtcc gtgaggtatt gatgtaggta ttaatttatc
    22321 acaattcgga aagttcgagc ttgtctttta gactaagtct tcgaacgttt tactgctaga
    22381 gtttcatctg aaccaaagtg aaacgctttt gatgaagtca agtaggcttt ttgttatact
    22441 aacaataaag ataagctaag gaggctgaga tgttagaaat tgtttcagaa gagctacgtc
    22501 actatcaaga acaaaaattg attgagtacc gtaacaaaaa tcagttagcc ccaaaaggag
    22561 gcattgtatt tgcaggtgat tctctcattg aattttttcc tttaaaaaaa gcttttggtt
    22621 catgtttgcc tattattaat cgaggtattg ctgggataga tagtcagtgg ttattgcgcc
    22681 atttttctgt ccaaattact gatttagagc ctaaacatat ttttttatta attggttgta
    22741 atgatatcgg gcttggatat gataaatgtc atattgtcaa gactattgta gagcttatta
    22801 gccagattcg tagtcattgt gtctacagtc agatttatct cttatcttta ttaccagttt
    22861 ccaacaatcc ccgatatcag aagactgtca aaataagaac aaatgctatg attgatgcta
    22921 ttaataaaga tttagcaatg attccaacta tagaatttat taatcttaat acttgtctta
    22981 aagacgaaaa aggtggttta tcagatgaga atactctaga tggtttacat cttaattttc
    23041 cagcttatgc taaactagct gaaattattc aagcttatat ctagcaaata aatgtactaa
    23101 tagcgatgag gcaagaagtc agatagcaga tggttcatca atcaattaag aaaaaagtta
    23161 tcaagatacc attaaaaata gttgctcaaa gttctttcaa atcaaaagat tatgatatcg
    23221 ctatgttgag ttttagtgta taatgataat taaaggagtt accatgaaat ttgaaaaaaa
    23281 acaagtcttc tatttagtcc ttacgtttat cttatgctat gggatcctag caaactggcg
    23341 aaatggaacg gctatcgtca cgactattta caaaacaagc cttccttttt tttatggagc
    23401 agcaggtgcc tatattgtta atattgtaat gagcgcttac gaaaaggtat atgtttatat
    23461 ctttaaagac tggtcacatg tcttaaaagt aaaacggggt atttgtttac tgttagcgta
    23521 tttgacattt tttattttaa ttacttggat tatttccatt gtcattccag acttaattac
    23581 aagtattagt actctaacaa aatttgatac tataacgata caagaagttg ttaacaatct
    23641 tgagcacaat aaactgttag cacgtactat tcagtatatt ggtggcgatg gcaaacttac
    23701 agagacgatt gctaactata gtcaacagtt attaaagcaa tttcttactg ttttgacaaa
    23761 tattttaaca tctgtcacgg ttattgcttc tgcaattatt aatcttttta ttagttttgt
    23821 tttttcgtta tacgttttag caagtaaaga agatctttgt cgtcagggaa atactttagt
    23881 agatacttat actggtaagt acgctaaacg cattcattac ttgttagagt tgttgcatca
    23941 gcgttttcac ggattttttg ttagtcagac cttagaagct atgattttag gttcgctgac
    24001 tgctagtggc atgtttatat taagattacc atttgcaggg actattggcg ttttagtagc
    24061 ttttacagca ttgattccag ttataggtgc ttcaattgga gcagctattg gatttatttt
    24121 aattatgact cagtccatgt cacaggccat tatttttatc atttttttaa ttattttgca
    24181 gcagattgaa ggtaatttta tttatccgaa agtagttggt ggatcgattg gattaccggc
    24241 tatgtgggta ttaatggcaa ttacaatagg cgcttcttta aagggaatag ttggtatgat
    24301 tattgcagtt cctttagcag cgacacttta tcaagtgatt aaagataata ttcaaaaaag
    24361 acaagctatt caaaaaaaac aagtttccta aaaggaactt gtttttttgt cgaataaaaa
    24421 gatggaggta atatgataaa tgtattctat aaaatgtgat gataataaag ccatgccaag
    24481 agaacgtttg atgcgactag gagcagagtc tctaagtaat caagaattat tagcaatttt
    24541 attacgaaca ggtaataaag aaaagcatgt cttagagctg tcatcctatc ttttatcgca
    24601 tttagacagt ctggcagatt ttaaaaagat gtctttgcaa gaattacaac atttggcagg
    24661 tataggaaaa gttaaagcga ttgaaattaa agctatgatt gagttggttt cccgaatttt
    24721 agcgaccgat aagacattaa ctgatagcgt attaaccagt gttcaggtcg ctgaaaaaat
    24781 gatggcagct ttaggagata aaaaacaaga gcatttagtc gtattgtatt tagataatca
    24841 aaatcgtatt tttgaagaaa aaactatttt tattgggact gtccgacgtt cacttgcaga
    24901 accaagagaa attttatact atgcctgtaa aaatatggcg actagtctca ttgttattca
    24961 taatcatcct tcaggaaata ttgaacctag ttctaacgat tattgcttta ctgaaaaaat
    25021 aaaacgatca tgtgaagatt taggcattat ctgtctagat cacattatcg ttagctataa
    25081 agattattat agttttcgag aaaaatcaac ccttttttaa atcagaagtc attgacgaat
    25141 aagcggaaca attgtagatc ttcatctcga acaccttgga gaagttcagg atgccactga
    25201 acacctaaaa aaggaatggc atcgttggtt gatatgactg cttcgatggt accatcacgt
    25261 ggatctctag cgattacttt taaatcctta gcaatagttt ttaaactttg gcgatgaaaa
    25321 gaattaatta atgtcttatg accgtaaata ggatataaga tagagtctgg ctcaataatc
    25381 atttcgtgtg ataagaaatc agaaggcgct tcttgccaat gtgagtcaat gtgttggtta
    25441 agatttcctc ctaaggcaac attcattaac tgtgtaccac gacaaatccc taagattggt
    25501 ttttttaatg ttatagcctc cttgatgata gctagctcaa atgtgtctcg ctctggtgaa
    25561 aaatcatcat caaaagcagc cttctcttct tgataatatt ttgggtcaac gttttgccca
    25621 ccaattaaaa tgattttatc aaccatagat acataagttt tagcggcggc ttcatcacca
    25681 atgggtaaaa gaagcggcag ccccccagat tgagtgactg cctgtacaaa tccagtaggt
    25741 gcatatgacc atgggagatt atccaaagcc atatttagtc tttgatttgc agttattcca
    25801 ataatcggtt tggtcattat acctccttaa tctagatgat tttgattcat aaaatagagt
    25861 agtgtctgga gctcactggt caaatcgaca gattgaacaa taactccttt aggaacttgt
    25921 aggtgaacag gagcaaaact caagattcct ttgattcctg cttcaataag ttgatcagta
    25981 acttcttgag catgaatgct gggaaccgtt aagatagccg tttcaatgtc agtgtttgca
    26041 atccgttctt tgacggatga gataccatgg actggaatat tatcagctgt tttagtacca
    26101 acaagagcgt tatcatcggt atcaaaaccc atggcaattt gcatcttatt acgatcatgg
    26161 aagcggtaat gtaatagagc acgccctata ttaccgcatc caactaagat aacgtttgtt
    26221 gtagagtgat cattaagcaa gtcagcaaaa aaattcatca atttggtaac atcatagcca
    26281 aacccacgac gccccaattc tccaaaataa gaaaagtcac ggcgtacagt agcagagtca
    26341 attcccattg catctgcaat ttgtttagaa ctggcttttt caacttggtc agcatggaat
    26401 cgtttaaaaa tacggtaata aagtgataag cgctttgcag tcgcttttgg aatagatttg
    26461 tcaataacca ctattttact ccttgtagat ttctcgttaa atatgtctgt ctttattgta
    26521 acaaaaagat tgtgaaaaat gcaacatttt gattgttttt gtatgagtta aaaaagctaa
    26581 aattagtttt agcactatat aatagtattc attaggaaag taagttatga cagtcaaaat
    26641 gaacaacatg aattaatagc aatagaagcg aaatcattta ttgacattgt gatatgacta
    26701 aaaaaacaaa atttaaagtt gattagacga ctgttttgct aa
//
LOCUS       DATWVB010000020        25798 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.020, whole genome shotgun sequence.
ACCESSION   DATWVB010000020 DATWVB010000000
VERSION     DATWVB010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25798
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.020"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            178..1461
                     /locus_tag="VCX65_001016"
     CDS             178..1461
                     /locus_tag="VCX65_001016"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEP5053482.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            1673..2248
                     /locus_tag="VCX65_001017"
     CDS             1673..2248
                     /locus_tag="VCX65_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEP5053483.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            2505..4109
                     /locus_tag="VCX65_001018"
     CDS             2505..4109
                     /locus_tag="VCX65_001018"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEP5053484.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRNVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
     gene            4277..5203
                     /locus_tag="VCX65_001019"
     CDS             4277..5203
                     /locus_tag="VCX65_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEP5053485.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLIKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
     gene            5257..5342
                     /locus_tag="VCX65_001020"
     tRNA            5257..5342
                     /locus_tag="VCX65_001020"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5291..5293,aa:Leu,seq:aag)
     gene            5549..6430
                     /locus_tag="VCX65_001021"
     CDS             5549..6430
                     /locus_tag="VCX65_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEP5053486.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            6812..7000
                     /locus_tag="VCX65_001022"
     CDS             6812..7000
                     /locus_tag="VCX65_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEP5053487.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            7152..7517
                     /locus_tag="VCX65_001023"
     CDS             7152..7517
                     /locus_tag="VCX65_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP5053488.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            7517..9181
                     /locus_tag="VCX65_001024"
     CDS             7517..9181
                     /locus_tag="VCX65_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEP5053489.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKA
                     EVKEFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            9418..10308
                     /locus_tag="VCX65_001025"
     CDS             9418..10308
                     /locus_tag="VCX65_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEP5053490.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHVRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFATKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            10538..11392
                     /locus_tag="VCX65_001026"
     CDS             10538..11392
                     /locus_tag="VCX65_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEP5053491.1"
                     /translation="MKSKKVVSVISLTLSLFLVIGCAKVDNNKSVNCKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            11585..12781
                     /locus_tag="VCX65_001027"
     CDS             11585..12781
                     /locus_tag="VCX65_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEP5053492.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            13044..13595
                     /locus_tag="VCX65_001028"
     CDS             13044..13595
                     /locus_tag="VCX65_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEP5053493.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKKHSDVR"
     gene            13662..14033
                     /locus_tag="VCX65_001029"
     CDS             13662..14033
                     /locus_tag="VCX65_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEP5053494.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            14071..15417
                     /gene="glnA"
                     /locus_tag="VCX65_001030"
     CDS             14071..15417
                     /gene="glnA"
                     /locus_tag="VCX65_001030"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEP5053495.1"
                     /translation="MAITVADIRHEVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDETDKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPIEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFISQWEIDHYIHNY"
     gene            complement(15645..17327)
                     /locus_tag="VCX65_001031"
     CDS             complement(15645..17327)
                     /locus_tag="VCX65_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEP5053496.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PNGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(17329..17559)
                     /locus_tag="VCX65_001032"
     CDS             complement(17329..17559)
                     /locus_tag="VCX65_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEP5053497.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            17843..18541
                     /gene="tsaB"
                     /locus_tag="VCX65_001033"
     CDS             17843..18541
                     /gene="tsaB"
                     /locus_tag="VCX65_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEP5053498.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHAPLEVIIEQLVEEGQLIFVGE
                     TAPFAEQIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            18513..18968
                     /gene="rimI"
                     /locus_tag="VCX65_001034"
     CDS             18513..18968
                     /gene="rimI"
                     /locus_tag="VCX65_001034"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEP5053499.1"
                     /translation="MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIR
                     RDQTDYFLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQGLGLASQLMTHLDSIESD
                     IFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHDR"
     gene            18958..19986
                     /gene="tsaD"
                     /locus_tag="VCX65_001035"
     CDS             18958..19986
                     /gene="tsaD"
                     /locus_tag="VCX65_001035"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEP5053500.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGNELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(20157..20426)
                     /gene="rpsN"
                     /locus_tag="VCX65_001036"
     CDS             complement(20157..20426)
                     /gene="rpsN"
                     /locus_tag="VCX65_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEP5053501.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(20647..21405)
                     /locus_tag="VCX65_001037"
     CDS             complement(20647..21405)
                     /locus_tag="VCX65_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP5053502.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSCQSDTH"
     gene            21645..22424
                     /gene="udp"
                     /locus_tag="VCX65_001038"
     CDS             21645..22424
                     /gene="udp"
                     /locus_tag="VCX65_001038"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HEP5053503.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            22445..23647
                     /locus_tag="VCX65_001039"
     CDS             22445..23647
                     /locus_tag="VCX65_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEP5053504.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            23677..24348
                     /gene="deoC"
                     /locus_tag="VCX65_001040"
     CDS             23677..24348
                     /gene="deoC"
                     /locus_tag="VCX65_001040"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEP5053505.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEAT
                     KTDSY"
     gene            complement(24443..25612)
                     /locus_tag="VCX65_001041"
     CDS             complement(24443..25612)
                     /locus_tag="VCX65_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEP5053506.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDDLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSTDQTFTCQKLIV
                     TTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNALKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
BASE COUNT         8180 a         4293 c         5458 g         7867 t
ORIGIN      
        1 ttagtaagcg aaaaagtcta acattaacct ttataaattg aaaataactg ttagtagact
       61 aatgacaggt agatactctt aatagcgcgt ttgatttcac gcataaaaag ctttaaaaac
      121 gctttaaatt atgataaaat gaactgtatc gaaattattt taaggagaaa tgacttaatg
      181 tctacatcat ttgaaaacaa agctacaaat cgtggcgtga ttacatttac aattagtcaa
      241 gataaaataa aaccagctct tgataaagct tttaataaaa tcaaaaaaga cttaaatgca
      301 ccaggtttcc gtaaaggaca catgcctcgt ccagtcttca accaaaaatt tggtgaagaa
      361 gttctttatg aagatgcttt gaatattgta ttgccagaag cttatgaagc agctgtgacg
      421 gaacttggtc ttgatgtggt tgcacaacca aaaatcgatg ttgtgtcaat ggaaaaaggg
      481 aaagagtgga cactttctgc tgaagttgtg acaaaacctg aagtgaaact tggtgattac
      541 aaaaaccttg ttgtagaagt tgatgcttca aaagaagttt cagatgaaga cgtggatgct
      601 aaaattgagc gcgaacgtca aaaccttgcg gaactcatta ttaaagacgg tgaagcagct
      661 caaggtgaca ctgttgtgat tgactttgtt ggttcagttg atggtgttga gtttgatggc
      721 ggtaaaggag ataacttctc tcttgaactt ggttcaggac aatttatccc aggttttgaa
      781 gatcaactag ttggtgctaa agctggcgat gaagtagaag ttaatgtcac attcccagaa
      841 tcttaccaag cagaagatct tgcaggtaaa gccgctaaat ttatgacaac tattcacgaa
      901 gtcaaaacaa aagaagtacc agagcttgat gatgagcttg caaaagatat tgatgaagat
      961 gttgacacac ttgaagactt aaaagtaaaa tatcgtaaag aacttgaagc agctcaagaa
     1021 actgcttatg atgatgctgt tgaaggagct gcgattgaat tagcagttgc aaatgctgaa
     1081 attgttgatt tacccgaaga aatgattcat gaagaagtca accgttcagt gaatgaattt
     1141 atgggcaaca tgcaacgtca aggaatctca cctgaaatgt acttccaatt gactggtaca
     1201 actcaagaag atttacataa ccaatattca gctgaagctg acaagcgtgt taaaacaaac
     1261 cttgttattg aagcaattgc taaagcagaa ggttttgaag caacagatag tgaaattgaa
     1321 caagaaatta atgaccttgc aacagaatat aacatgccag ctgaccaagt tcgttctctt
     1381 ctttcagcag atatgttgaa acatgatatt gcaatgaaaa aagcagttga agtgattaca
     1441 agcacagcaa gcgttaagta atcttattaa ggaacaaaac gtacaagccg gattagaacg
     1501 tctttctagt ctggtttttc tttttctaaa gataaggaat tagttaaacg ttattttaat
     1561 gaattagctt taaagatttg tcaagaagaa gtgatatgag ttgataaaag ttttgacgaa
     1621 ttactttttt tagcgtaaaa tggtagagaa tgataaaata aggagaactg ccttgaaatt
     1681 agacgtattt gcaggacaag aaaaaagcga gctttccatg attgaagtgg cgcgtgccat
     1741 tttggaagaa cgcggtcgcg acaatgagat gtactttagc gatttagtca atgagattca
     1801 aaattactta ggaaaatctg atgcaggtat tcgtcatgca ttaccatttt tctatactga
     1861 cttaaatacg gatggctcat ttattcctct aggtgaaaac aaatggggac ttcgttcgtg
     1921 gtatgctatt gatgaaattg atgaagaaat tattactcta gaagaagatg aagatggcgc
     1981 acaaaaacgt aagaaaaaac gcgttaatgc tttcatggat ggagatgaag acgctattga
     2041 ttatagagat gatgatccag aagatgaaga tttcacagaa gaatcagctg aggttgaata
     2101 tgatgaagaa gatccagatg atgaaaaatc agaagtggag tcatatgatt cagaattgaa
     2161 tgaaattatc cctgaagatg attttgaaga agttgatatc aatgaagaag acgaagaaga
     2221 tgaagaagat gaagaaccag ttctctaatg tctttagttc agaaataaaa atgtgattat
     2281 catttgacaa attgtctatt atagtttata ttattattcg ggcacctctt tatgaggtca
     2341 ggcaaaagct ctctagttaa tagggggcta tttttgtttt ctagaataat gccagtttgc
     2401 ctctatattt agaaaactaa ggtgatacct aaccaatgtg gaaccaacta atagggaatt
     2461 aacaagaaag caatgctttt attcagctta tataaaggag tactatgacg aaatacattt
     2521 ttgtaactgg tggtgttgta tcatcaattg gcaaaggaat tgttgcggca agtcttggcc
     2581 gattgttaaa aaatcgtgga cttaaggtga cgattcaaaa atttgatcct tatattaata
     2641 ttgatccagg gacgatgagc ccctatcagc atggagaagt atatgtgaca gatgacggtg
     2701 ctgaaaccga cttggatttg ggtcactatg aacgttttat tgatatcaat cttaataaat
     2761 attccaatgt tacaacaggt aaaatttata gtgaagtcct tcgtaaagaa cgtaaaggtg
     2821 agtaccttgg agcgactgtt caggtgattc ctcatatcac agatgccctt aaagaaaaaa
     2881 tcaaacgcgc agcttcaaca acggactctg atgtaattat tactgaggtc ggggggactg
     2941 ttggcgatat tgaaagttta ccgttcttag aagctcttcg tcagatgaaa gctgatgttg
     3001 gttctgaaaa tgtgatgtat attcacacca ccttgttgcc atatttaaag gcagcgggtg
     3061 aaatgaaaac taagccaacg caacattccg ttaaagaatt gcgtggttta gggattcaac
     3121 cgaatatgtt ggttattcgt acggaagagc cagttgagca ggggattaaa aataaattgg
     3181 ctcagttctg tgatgtgaat tcagaagctg ttatcgagtc acgtaatgta gaacacttgt
     3241 atcaaattcc attgaacttg caagcccaat caatggatca gattgtttgt gatcatttga
     3301 aattgaatgc gccacaagct gatatgactg agtggtcagc tatggttgac aaggtgatga
     3361 atttaagaaa aacaacaaaa attgccttgg ttggtaaata tgtggaattg ccagatgcct
     3421 acttatctgt tgtggaagcc ttgaaacatt ctggttatgc caatgatacc gcaattgacc
     3481 taaaatgggt caatgctaac gatgtgacgg tggataatgc agctgacttg ttgggagatg
     3541 cggatgggat tattgtacca ggtggttttg gtcaacgtgg tacagaaggc aagatccaag
     3601 cgattcgcta tgcccgcgag aatgatgtgc caatgcttgg tatctgtctt ggcatgcaac
     3661 tgacttgtgt tgaatttgct cgccatgtcc tcaatatgga aggtgcaaac tcttttgaat
     3721 tagagccaag tactaaatac cccatcattg atatcatgcg tgatcaaatt gatattgaag
     3781 atatgggagg tacgcttcgt ctgggattgt acccatgtaa attgaaacca ggttcaaaag
     3841 cagcaatggc ttacaataat caagaggtgg tgcaacgtcg tcatcgtcac cgttatgagt
     3901 tcaacaacaa attccgtcca gaatttgaag cagctggttt tgttttctca ggggtatcac
     3961 ctgacaaccg cttagttgaa attgtagaat tgaaagagaa aaaattcttt gtagcagctc
     4021 aataccaccc agaattgcaa agccgtccaa atcgtcctga ggagctatac accgcttttg
     4081 ttacagctgc tattaaaaat agcaattagt ggttttaagg gtaagtttgt ggcattctac
     4141 ttggctggca gatactgata aagattacta gctattagag ggatcttttc tataaaaata
     4201 gcattagaaa aagaaaaacg tgatattttt aggttagcac tttctttttc agtcattttt
     4261 ttgtaaaata cttggtatga aaactattcg aatagcaaag tatttaggaa ttctattcct
     4321 tttgataact cttattagcg taggtgctag tttttatttc tttcatgttg cacaaataag
     4381 agaagagaaa tcgtttatta ataataagaa acggagtaca aataatccat tatacccagc
     4441 tgaacagtct tttgacgctt taccttacga aaaacgtcaa ctaacaaatc gtgggttaaa
     4501 acaagtgggg tggtacttac cagctgctca aaaaacaaaa aagacagcta ttgttgttca
     4561 tggttttacg aatgacaaag aagatatgaa gccatatgcc atgctttttc atgatttggg
     4621 ctataatgtc ttaatgccag acaatgaggc ccatggggaa agtgaaggga acttgattgg
     4681 ttatggctgg aatgaccgcc ttaatgtcat ggcttggaca gaccaactga ttaaggaaaa
     4741 ccctgaaagc caaatcacac tctttggctt atctatgggt gctgcaacag taatgatggc
     4801 aagtggtgag cgattgcctg cgcaagtcac ctccctcatc gaagattgcg gttataccag
     4861 tgtttgggac gaattgaagt ttcaggccaa ggctatgtac aacttgcctg cctttccttt
     4921 actctatgaa gtctctgcct tatctaagat tcgagcaggt tttagttacg gagaagcgag
     4981 ctcagtgaaa cagctggcta aaaataaacg tccaacttta tttatccacg gtgataagga
     5041 tgattttgtt cctacaaaaa tggtttatga caattataag gccacgaaag gtcctaagga
     5101 aatcttgatt gttaaagggg caaaacacgc caaatccttt gaaacaaacc cagaacaata
     5161 ccagaaaaaa attgccgctt ttttgaaaaa agttgagaaa taagtattga cagttaaact
     5221 cacagttgct ataataattt atgttactga tgagtagcgg ggatggcgga attggcagac
     5281 gcgcaggact aaggatcctg tgaccgcttt aggtcgtgtg ggttcaagtc ccactctccg
     5341 cataatgtaa gaggtgaatc attgattcgt ctcttttttt tggttaaatg aaggataaga
     5401 aggcatagat ttactggaga aaacttttga taatctgctt ttggaaaacg ctttaagctt
     5461 gtgaaagact agaaatttat ggaaaattgt gctagaatga acaatgtaaa cggggagtta
     5521 tcccgaaaaa taagaggagg ccttacaaat ggcaatcgtt tcagcagaaa aatttgtcca
     5581 agcagctcgt gaaaacggat atgctgttgg tggatttaac acaaacaact tagagtggac
     5641 tcaagcaatc ttgcgtgcag cagaagctaa acaagctcca gttcttatcc aaacatcaat
     5701 gggtgcagca aaatacatgg gtggttataa agtatgtcaa tctcttatta ctaaccttgt
     5761 tgagtcaatg ggtatcactg ttcctgttgc tatccacctt gatcatggtc actacgaaga
     5821 tgctcttgag tgtatcgaag taggttacac ttcaatcatg tttgacggtt cacaccttcc
     5881 agttgaagaa aaccttgcta aaactgcaga agttgttaaa attgcacatg ctaaaggcgt
     5941 ttcagttgaa gctgaagttg gtacaatcgg tggtgaagaa gacggtatca tcggtaaagg
     6001 tgagctcgct ccaatcgaag atgctaaagc aatggttgaa actggaattg acttcttggc
     6061 agctggtatc ggtaacatcc acggtccata cccagaaaac tgggaaggtc ttgctcttga
     6121 ccacttagaa aaattaacag cagctgtacc aggtttccca atcgtattgc acggtggttc
     6181 tggtattcct gacgatcaaa tcaaagaagc aatccgtctt ggtgttgcta aagttaacgt
     6241 taacactgaa agtcaaatcg ctttctctaa cgcaactcgt gaatttgctc gtaactacga
     6301 agctaacgaa gcagaatatg atggtaaaaa attatttgac ccacgtaaat tcttggctcc
     6361 aggtatgaaa gctgttcaag gtgctgttga agaacgtatc gatgttttcg gatcagctaa
     6421 caaagcataa tttagagtat taaataccct aaagccctct tgagggcttt tttagataca
     6481 attgacaccc taaaatggat accagtttct gtgaaacaat ctttgattgt gaacaaacaa
     6541 agcataattt agagtattaa aatctggacc ctgctatcta tggtaagtct ttttgttatt
     6601 gttaaagagg ttaagcggaa tgttaatatg ttttagctaa aaaatgtagt gaaaaatgag
     6661 tacgtagact attgtaatag taattccgta aaattgttga aaaagaaaat gggaaatacc
     6721 ttgtcaaatt aagcacccta tgatagaata gataggtatg tggtgctagc acatccgtaa
     6781 acatattcta cgtaggagga aacagatcaa aatggctaaa gtatgttatt ttacaggacg
     6841 taaaaccgtt tctggaaaca accgttcaca cgcgatgaac caaacgaaac gtacagttaa
     6901 accaaacctt caaaaagtta cgatccttgt tgatggtaaa cctaaaaaag tttgggcttc
     6961 tgctcgtgcg cttaaatctg gtaaagtaga acgcatctaa tagaaataag ccttagggct
     7021 ttttttatta gcttatttct atccataagc tagtcagggt aataaacgct atcgttaact
     7081 attctatctc ttttacatta cttctaaaat atgataaaat aggatgataa aaactttttg
     7141 aggtagtaac tatgactgta aaaattaata caaaagatgg tctaatcgag ctatccgacg
     7201 atgtgattgc aactgtcgtg ggaggatcag caacggaaat ttttggtgtt gttggaatgg
     7261 ccagcaaaag tgcaataaaa gacaattttc aatcactact tcgcaaagaa aactacgcta
     7321 agggtgttgt agtaaaatca acagatctgg gtatttctgt tgatgtctac actgtgatga
     7381 gttatggtgt gaaaatcagt gaagtctcta aaaatatcca agaacgcgtg aaatttaacc
     7441 ttgaaagtca gcttggtctc actgctgata tggtcaatgt ttacgtgcaa aatattaagg
     7501 ttgtaggaga aaattagtgt caaatattac aacaagctta ttccaagaaa tggtccaagc
     7561 ggcagcgact cgccttggca aacaagcaga atatgttaat tccttaaatg tttttcctgt
     7621 tccagatggt gatacaggaa caaacatgag tatgactatg gacaatggtg ccaaggaagt
     7681 tgctgataaa cctgcgtcaa ctgtgggaga agttggacaa atgttatcaa aaggtctttt
     7741 gatgggagcg cgtggaaatt ctggagttat tacttcacaa ctttttcgtg gttttggtca
     7801 aagtattaag ggaaaagatg agctgacagg taaagatttg gcacaagcct ttcaagtggg
     7861 tgtagaagtt gcctacaaag cagtgatgaa acctgttgaa gggacaatct tgacagtatc
     7921 tcgtggagca gcaaccgctg ccttaaaaaa agcggatctt acagacgacg ccgtggaagt
     7981 catgcaagct gctttagacg gtgccaaagg tgcccttgct aagacacctg atttattacc
     8041 agtccttaaa gaagttggtg tggttgattc aggcggtcaa ggtcttgtct ttatctatga
     8101 aggtttccta tctgctttga atggcgacta tgtgacttca gcagacttta aagcgactcc
     8161 tgctaacatg tctgaaatga ttaatgctga gcatcacaaa tccgttgttg gtcatgtggc
     8221 tactgaagac attacctacg gttattgtac tgaaatcatg gttgccctta aacaaggccc
     8281 aacctatgtg aaagaattca actatgatga gtttcaaggc taccttagtg gccttggtga
     8341 ctcgctgtta gtggtcaatg atgatgagat tgttaaagtt cacgtccata ctgaagaccc
     8401 cggacttgtg atgcaagaag gtcttaaata tggttcgctc atcaagatta aagtggacaa
     8461 tatgcgtaac cagcatgaag cacaggttca aaagactgat gtcgaaaaaa acaaggctga
     8521 agtaaaagaa tttggcttga ttgcagtagt agctggagaa ggtttatctg aaattttcaa
     8581 ggcgcaaggt gttgattacg tgatttctgg tggtcaaacc atgaatccat ctacagaaga
     8641 tattgttaaa gctattgaag cagttaatgc caaacaagtc attatcttgc caaacaataa
     8701 aaatatcttt atggctgccc aatctgctgc agaagtggtg gatatcccgg ctgctgttgt
     8761 tgcaacacgt actgttccgc aaggatttac cagcttgttg gcctttgatc cttcaaaatc
     8821 tttagaggac aatgtagcag atatgtcaac tagtctttct gacgtggtca gtggaagcgt
     8881 tactttggca gtccgtgaca ccaccattga tggtttagaa atccatgaaa atgatttctt
     8941 gggaatggtt gatggtaaaa tcatcgtttc aaacccagac atggaagcaa ctctaaaagc
     9001 tgcctttgaa aagatgattg acgaagatag cgagattgtg actatctttg ttggtgaaga
     9061 aggtgatcaa gacttagcag aagaacttgc tgggtattta ggagagactt acgaagatgt
     9121 ggaagttgag atccatcaag gagatcagcc tgtttaccca tatctcatga gtgtagaata
     9181 atagaataca ataaaaaaag aggagttagg caaaggtctg actctttttg tctatattga
     9241 tgtcgtaatg agtggtttta gtgatggtaa gcccctaaaa aatgagggta atccatcaca
     9301 aagctaatgg ttacgattta gtttgacaaa acctagaaaa acattataat tgtattataa
     9361 caataagtca agaactgaaa acggttcagt tctaagatat gacaaggagg agattttatg
     9421 ttaggaccat ttatctttat tgcttttggg gttattgtaa tcctagctat tgttgccagt
     9481 accctttatg ttgttcgtca acaatctgtt gccatcgtgg aacgttttgg taggtaccaa
     9541 aaaacagcca cgagtggtat tcatgtccgc cttccgtttg ggattgacaa aattgctgcg
     9601 cgtgtgcagc tgcgtctttt acagtcagaa atcatcgttg aaaccaaaac caaggacaat
     9661 gtgtttgtaa ctttgaatgt tgccactcag tatcgtgtta acgaacaaaa tgtaacagat
     9721 gcttactaca aattaatgaa acctgaatct caaatcaagt cttatattga agatgccttg
     9781 cggtcatccg tgccgaagtt gaccttagac gaattgtttg agaaaaaaga tgaaattgcc
     9841 ttggaagtac aacatcaagt ggcagaagaa atgtcaacct atggatatat tattgtcaaa
     9901 accttgatta ccaaggtgga gcctgatgct gaagtcaaac agtcaatgaa tgaaatcaat
     9961 gcggctcaac gcaaacgtgt agctgctcaa gagttggcaa acgcagataa aattaaaatt
    10021 gtgacagcag cagaagcaga ggctgaaaaa gatcgattgc acggggtagg gattgcccaa
    10081 cagcgtaagg ccattgtgga tggtttggcg gagtctattc aagagcttaa agaagcgaat
    10141 atttccttaa acgaagaaca aatcatgtcc attttgttga ccaaccaata cctggatacc
    10201 ctcaatacct ttgcgacaaa aggaaaccaa accctttttc taccaaatac accaagtggg
    10261 gtagaggata tccgtacaca agttttatct gcccttaaaa caaaataacg tgtaaaagct
    10321 tggctaaaaa gttgctcaat actggattta gcagaaggct atcatacctt gtgaagtggc
    10381 aaacgacgaa atgaatacat tacttttatt ggagaaatga aagtaaaaaa agcctttttc
    10441 atgattaaca acatagtatt gattaaatgt taagttgtat tgacttttaa attaaataag
    10501 tttaaaatca acttaataag caaaaaggag attttcaatg aaatccaaaa aagttgttag
    10561 tgttatatca cttaccttat cccttttttt ggtgataggt tgtgctaaag ttgataacaa
    10621 caaatcagtt aattgtaagc ctgctactaa acaaacctat aatagctata gtgatgacca
    10681 attaagatcg cgtgaaaata ccatgtctgt tttatggtac cagcgagctg cggaaactca
    10741 agcgctttat ttacaggggt atcagttagc aacggatcgc ttaaaagaac aactcaataa
    10801 accaacggat aaaccttatt caattgtatt agatattgac gaaacagttc ttgataatag
    10861 cccttatcaa gctaaaaatg ttttggaagg aacaggattt acacctgaaa gctgggatta
    10921 ttgggtacaa aagaaagaag caaaaccggt tgctggtgct aaagactttt tgcaatttgc
    10981 agaccaaaat ggtgttcaaa tttactacat ttcagacaga tcaactactc aagtagatgc
    11041 tacaatggaa aatctccaaa aagaaggtat tccagtacaa ggtcgtgatc atcttctatt
    11101 cttagaaaaa ggcgtaaaat caaaggagag tcgtcgtcaa aaggtcaaag aaacaactaa
    11161 tgtaacgatg ctatttggtg ataatcttct agattttgct gatttttcaa aaaaatctca
    11221 agaagataga acagctttat tatcagattt gcaagaagag tttggaagac gctttatcat
    11281 tttccctaat cctatgtatg gttcatggga aggtgccatt tataaaggtg aaaagctgga
    11341 tgtgcttaag caactagagg aacgccgtaa aagtttaaaa agctttaaat aaagtaattg
    11401 aaaaagaggt gcaaaagaaa atgtaacctc tttttaagta ctattatttt ctgaaaatag
    11461 ggttaatgac tgaaaaaaat gttgattttg tgaaatgatt attttattat tttcatattt
    11521 tatctttatg ctaggaattg tggtataatg gaggagtata aaaaatatta aggagtctat
    11581 tcacatggct aaattgactg ttaaagacgt tgatttgaaa ggtaaaaaag tcctcgttcg
    11641 tgttgacttt aatgtgcctt tgaaagatgg cgttatcact aacgacaacc gtatcactgc
    11701 ggctcttcca acaatcaagt atatcatcga acaaggtggt cgtgctatcc tcttctctca
    11761 ccttggacgt gttaaagaag aagctgacaa agaaggaaaa tcacttgcac cggtagctgc
    11821 tgatttagct gctaaacttg gtcaagatgt tgtattccca ggtgttactc gtggttcaaa
    11881 attagaagaa gcaatcaatg ctttggaaga tggacaagtt cttttggttg aaaacactcg
    11941 ttttgaagat gttgacggta agaaagaatc taagaatgac gaagaacttg gtaaatactg
    12001 ggcttcactt ggagatggaa tcttcgttaa cgatgcattt ggtacagcac accgtgctca
    12061 cgcatcaaac gtaggtattt cagcaaacgt tgaaaaagct gtagctggtt tccttcttga
    12121 aaacgaaatt gcttacatcc aagaagcagt tgaaactcca gaacgtccat tcgtagctat
    12181 tcttggtggc tcaaaagttt ctgataagat tggtgttatc gaaaatcttc ttgaaaaagc
    12241 tgataaagtt cttatcggtg gtggtatgac ttacacattc tacaaagctc aaggtatcga
    12301 aatcggtaac tcacttgtag aagaagacaa attggatgtt gctaaagacc tccttgaaaa
    12361 atcaaatggt aaattgatct tgccagttga ctcgaaagaa gcaaacgcat ttgctggtta
    12421 cactgaagtt cgcgacactg aaggtgaagc agtttcagaa ggcttccttg gtcttgacat
    12481 cggtcctaaa tcaatcgcta aatttgatga agcacttact ggtgctaaaa cagttgtttg
    12541 gaacggacct atgggtgtct ttgaaaaccc tgacttccaa gctggtacaa tcggtgtcat
    12601 ggacgctatc gttaaacaac caggcgttaa atccatcatc ggtggtggtg attcagcagc
    12661 agctgctatc aaccttggcc gtgctgacaa attctcatgg atcagtaccg gcggaggcgc
    12721 tagcatggaa cttctcgagg gtaaagtatt accaggtttg gcagcattga ctgaaaaata
    12781 atagtcatta taatatatag taaagggcat gctgatgcat gtcttttttt agttgatcat
    12841 gtacagttat tgaactttcc ctaacttcac ttatcattta ctagttttta gatatagtgg
    12901 tatttggctg acactgcaat tttcaaaagt ttatgacgat ttcatatcaa ttggtttata
    12961 aaagatatcc taatcataaa taaaacgttt accaaaaggg ttttatggat tgatatgtta
    13021 aaatagatag tgaagggata ggtatgaaaa cgttaagaaa attattatct aattacaagt
    13081 ttgatattaa aaagtttaaa ttgggaatga gaacattgaa aacaggctta tcggtctttt
    13141 tagttttatt ggtttttcat ttatttggtt ggaaagggct tcaaattggt gctctaactg
    13201 ctgtatttag tttaagagaa gactttgata aaagcgtgca ctttggcttt tctagaatta
    13261 ttggtaatag tataggtggc ctactctcct tagtattttt tgcattcaat gagatatttc
    13321 atcaagcttt ttgggttact ttattaattg ttcctatttg taccatgtta tgtatcatgg
    13381 ttaatgttgc atgtaataat aaatcaggta ttattggggc agtggctgct cttttgatta
    13441 ttacactgtc tattccaaca ggacaaacgt ttatttatgt gacttcgcgg gtatttgaaa
    13501 cattttgtgg cgtctttgta gctattttag ttaatactga tgttgaactt attaaaaata
    13561 aatggtttaa caaaaaacac agtgatgtta gataatataa catatatact tgacaggtta
    13621 tttttttcag cctataataa ggaagatgaa aggagtttgt catgaaagaa aaagaactta
    13681 gacgctcaat ggctgttttt cctattggaa cggtgatgac attaacagat ctctctgcga
    13741 gacaaattcg ctattatgaa gatcaaggtt taattaagcc tgaacgaacg caagggaatc
    13801 ggcgtatgtt ttccttaaat gacatggacc gacttttgga aattaaagat tttttgtctg
    13861 agggattaaa tattgcagct attaaacgcg aatatgtcga gcgtcaaggt aagttaatgc
    13921 aaaaacaaaa agctctaaca gatgcagatg tcagacggat cttacatgat gaaatgctga
    13981 cacaaagcgg tttttctact ccctcacagc atattggtaa ttttcgtatt taagatatga
    14041 attgtataaa atttaaagga gacctattta atggcaatca cagtagctga cattcgtcat
    14101 gaagtcaaag aaaaaaatgt aacgtttctt cgcttgatgt tcactgatat catgggcgtt
    14161 atgaaaaatg tggagattcc tgcaacgaaa gaacagttag acaaagtatt gtctaacaag
    14221 gttatgtttg atggttcatc tatcgaaggt tttgtacgga tcaatgagtc agatatgtac
    14281 ctttaccccg atttagacac ttggattgtt tttccctggg gagatgaaaa tggagcagtt
    14341 gcaggtttaa tttgtgatat ttatacagca gaaggaaagc cttttgcagg agatcctaga
    14401 ggaaatttaa aaagagccct gaaacacatg aacgagatcg gctacaaatc atttaatctt
    14461 gggccagaac cagaattttt cctttttaag atggatgata aaggtaatcc gacacttgaa
    14521 gttaacgata atggtggtta ttttgattta gcgccaattg acttagcaga caacacgcgc
    14581 cgtgaaattg tgaatatttt aacgaaaatg ggttttgaag tggaagctag tcatcatgaa
    14641 gtggctgttg gtcaacatga gattgatttt aaatatgcag atgttttgaa agcttgtgat
    14701 aatattcaaa tttttaagct agttgtaaaa acgattgccc gtgaacatgg actttatgct
    14761 acttttatgg ctaaaccaaa atttggaata gctggatcag ggatgcactg taacatgtct
    14821 ttgtttgata accaaggtaa taatgctttt tatgatgaaa ctgataagcg aggaatgcag
    14881 ctatcagaag atgcttatta tttcttggga ggactaatga agcatgctta taactacact
    14941 gctatcacta accctacagt gaattcttac aaacgattag ttccgggtta tgaggcacct
    15001 gtttatgtcg cttgggctgg aagtaatcgt tcaccgctta tccgtgttcc agcatcacgt
    15061 ggtatgggaa cgcgtttgga gttacgttcg gttgatccga cagctaatcc ttatttagcc
    15121 ttggctgttc tcttggaagc tggattagat ggtatcatta acaaaattga agctccagaa
    15181 cccattgaag ctaacattta taccatgaca atggaagaac gaaatgaagc aggcattatt
    15241 gatttgccat caacgcttca taatgcctta aaagctcttc aaaaagatga tgtggtacaa
    15301 aaggcactag gttaccatat ctacactaat ttcttagaag caaaacgaat tgaatggtct
    15361 tcctatgcaa cttttatttc tcaatgggaa attgaccatt atattcataa ttattagact
    15421 tatcaggacc tgctcaagtt gagtgggtct tttggatgag ctattgtatt tgagctagca
    15481 agctattatt agctgatcgg acaccaattg attttccatt atagaaaact aaaaaccagt
    15541 ccatgttcta tgaggactgg tttttagttt gataattatc tgaactagaa ctgatatgtt
    15601 aaagatatag acagatagta ttaagaaatg agtcttattt gattttagtg cttatcaggt
    15661 gttaagacca tcggaattat aattggttca cgctcagtct tttcatacaa gaatggacga
    15721 agagcattga cgatagcacc gttaactgat tggatgctag catccttatt ttttaaagca
    15781 atacggatag cgttaaagag cacacgttgg ctttcgcgga tcaagtcacc tgactcacgc
    15841 atataaatga aaccacggct cagaatatct ggtccagcta aaatcatttg tgtgttaaaa
    15901 tcaacagttg caacagctaa gacaacacca tcttctgaca aatcacggcg gtctcgtaaa
    15961 acggctgctc caatatcccc gatgccatta ccatccacgt agatgtcttg ggcattaaag
    16021 tgaccagcaa tacgcgcact gtcactggtt aaagctagaa cgtctccatt ttccataata
    16081 aagatatttt cttttggaat accaatatcc atcgccagtc ctgcatgaac tttttgcatg
    16141 cgatactcac catgtactgg catgaaatat tttggtttaa tcaaactaag catgagcttt
    16201 tgttcttgct gtcctccatg accagaagta tgaatattat tgacttttcc atgaataaca
    16261 tcaacaccag cttcttggat ggtattgatt aatttattga cacttgtggt attaccaggg
    16321 attggacttg atgagaaaat cacagtatca ccaggctgta aagttacttg acgatgagtg
    16381 ccattagcga tacgagcaag tgctgccata gactcacctt gactacctgt acacataatt
    16441 aaaacttcac tagcatgaag atttttaagt tcgcttggct caatgaaggt accatttgga
    16501 actttaatat agccaagttc aataccgtta acaattgctt tttccataga acgaccaaaa
    16561 acggcaattt tacgtcccgt tttaacagca gcttctgcag cctgttgcaa acggtagatg
    16621 tttgaagcga aggaagcaaa aataatacga ccatgaatac cttcgataat ttttaaaatg
    16681 gattggccaa caactttttc agagttagta aaggttggga tttcagcatt agttgagtct
    16741 gataataagc aaaggacacc ttcttcacca agcgctgcca tacgttgtaa atctgcagga
    16801 tctcctactg gcgtgaagtc aaatttaaaa tcaccagtac agataatctt accttgaggg
    16861 gtgtggataa caataccgac cggttctgga atggaatgag tagtcttgaa gaaagtgacg
    16921 ctcatgtttt taaaagttaa ctcggtgttg tgattgattt cgtaaacagt tgcttcacgc
    16981 caaagaccat gttcttccaa tttaccacgg ataagagcaa gtgctaaagg tcctgcgtag
    17041 atagggatat tagcctgttt gagaagaaat ggaataccac caatgtggtc ttcgtgacca
    17101 tgtgtaataa caagagcttt tacccggtct aagttatcga caatgtaaga atagtctgga
    17161 ataacgtaat caattcccaa aagatcatct tctgggaatt tgataccggc atcaacgata
    17221 atgatctcgt cttgatactc aataccataa gtattcttcc caatctctcc cagaccacca
    17281 atggcaaaca ccccaacttc attaggtttt aaactgatat ttgtcatctt agaactccgt
    17341 taattcaaaa acaccggtct ctttttcgta atcgaggtgt ttgtcagaaa gtagctcgat
    17401 aaattccacg ttataatagg tgttatcttc aacgagacga cgagccttga tacggccatc
    17461 gagttcatca gtagcatcaa tattaagata gagtgcttta gtactttcac gacgtgggct
    17521 ttgatccttt gtttcttgat agaaaacttt ataaatcatt tgttttttat tcctttcgtt
    17581 atgaatcaat tatccaaaca ataataaata ggtcaaaagg taggtgttcc attttgacgg
    17641 ttttatatgt tgtcattatt gtgtagtaga ttaattcctg attctgtgca attattataa
    17701 ttataccata aacttagctt ttagtaaaaa atttaggtac atttatggta tagtctaaat
    17761 caaattaaga gtcagccttt ttgtttatga ttcttaattt gtgttataat tgatactaga
    17821 acttgcagta gaaaggcata aaatgaagac acttgcattt gatacctcaa ataaaacctt
    17881 gtcccttgct atacttgatg atgagacact tctagcagat atgaccctta acattcagaa
    17941 aaatcatagt gttagcctta tgcctgctat tgattttttg atgacttgta ctgatcttaa
    18001 acctcaagat ttagaaagaa tagtggttgc aaaaggccct ggatcttaca caggtttacg
    18061 agtggcagtt gctactgcaa aaacgttagc gtacagttta aatattgcat tggtcgggat
    18121 ttccagtcta tatgctttgg ctgcgtctac ttgtaaacag tatccaaata ctttggtggt
    18181 gccattgatt gatgctagaa ggcaaaatgc gtatgtaggt tattatcggc aaggaaaatc
    18241 agtgatgcca caagcccatg ctccactaga agttattata gaacaattag tagaagaagg
    18301 gcagctgatt tttgttgggg agactgctcc ttttgctgag caaattcaaa agaaactacc
    18361 tcaggcgata ctacttccaa ccctgccttc tgcttacgaa tgtggtcttt tggggcaaag
    18421 tttggcacca gaaaatgtag acgcctttgt ccctcaatat ctcaagagag tggaagctga
    18481 agaaaactgg ctcaaagata atgagataaa agatgatagt cactacgtta agcgaatcta
    18541 atatgaaaac agttgaagaa caagcaaaaa atatttatca gcttttggaa atggtttatg
    18601 gcacgtctcc ttggacttta gaacaagtat taatcgatat acggcgggat caaacagatt
    18661 atttcctact atatgatcat gataaattgc taggtttttt agctattcaa gatttagctg
    18721 gtgaagttga aatgactcaa attgctatac tacctagtca tcaaggactt gggctagcgt
    18781 ctcaattgat gacgcattta gatagcattg aaagtgacat ctttttagag gttagagaat
    18841 ctaatcatag agcacagggt ttatatcaga agtttggttt taaatttatt ggcaaaagac
    18901 cagactacta tagaaatcct atagaaacag ctttattgat gaaacgggaa ggaaaacatg
    18961 acagataggt atattttagc agttgagagt tcttgtgatg agaccagtgt agcgatttta
    19021 aaaaacgaaa gtaccctctt aagtaatgtc attgcaagtc aggttgagag ccacaaacgc
    19081 tttggtggtg tggtgccaga agtagctagt agacaccatg tcgaagtgat tacgacttgc
    19141 tttgaggatg ctttgcaaga agctggcatc agtgcttcag atttatcagc agttgcggta
    19201 acttatggcc ctggacttgt tggagccttg ttagttggat tagcagctgc gaaggctttt
    19261 gcttgggcaa atcatttacc tttgattccg gttaatcata tggcaggtca cttaatggca
    19321 gcgcgtgaac aaaagccttt agtttatcct ttaatagcac tattggtttc aggaggacac
    19381 acagaattgg tttatgtccc agagccaggg gattatcata ttattggcga gacgcgtgac
    19441 gacgctgttg gtgaggctta tgataaagtt gggcgtgtga tgggcttaac ctatccggca
    19501 ggacgtgaaa ttgatcagtt ggctcataaa ggtcaagata cttatcattt ccctcgtgct
    19561 atgataacag aagaccactt agaattttct ttttcaggac tcaagtccgc ttttatcaat
    19621 cttcatcata atgctaagca aaaaggcaat gaactgattc tagaagattt gtgtgcatct
    19681 tttcaagcag ctgttctaga tattttattg gccaaaacaa aaaaagctct gagcagatac
    19741 cctgcaaaga tgcttgtagt ggctggtggt gtagcggcaa atcaaggatt acgagataga
    19801 ttagcacaag aaattacaca tatagaagtt gtgattccta aactaagact ctgtggagat
    19861 aacgcgggta tgattgcttt agcagcagct attgagtatg acaaacagca ttttgctaat
    19921 atgagcctaa acgcgaagcc tagtttagct tttgaccagt ttccagacag ttttgtaata
    19981 aactagtcac acttgctagt tagtaagatt tataatggat aagaatctcc ctttgaaaaa
    20041 acaacccggt atcttggcat accgggttgt catgatgata agtaattggc ttctatggtt
    20101 actaataatt cagataatta cctgcaaaat aattgtctgc ctaaggtgaa gtaagcttac
    20161 cagctagctt tagtgacgcc aggaagctgt cctttgtgag ctaagtcacg gaaattgata
    20221 cggctaacac caaacttacg catgtaagca tgaggacggc cgtcaatttt gtcgcggttc
    20281 ttcaagcggt ttggatttga atcacgaggc aatttgcgca gtgattcata atcgcccttc
    20341 gcttttaagt cacgacgaag gtcagcgtac tgttcaatca gttggagctg cttttggtat
    20401 ttagcaattt ttgacttttt tgccattgct ttctccttct taatatttaa taacctcaga
    20461 gtcgttatca gcgctctgaa tccacttaac tggtatttaa ctggttaagt ggatatataa
    20521 tcattataca ataaataaaa gcaaaagcaa ataaaaaaaa ttaactagtt atctttttta
    20581 gccataatat caaaaaactc cacatctaag tgtgggagtc aggtattaat aactgtttaa
    20641 aggtgtttaa tgagtgtcgc tttggcaact ttgagattga acttttaagt caaataaatc
    20701 agcaggaacg tagtgtttgg ttgagaccaa gatgtcttta ccattgtaga gagtttcttg
    20761 gattaaaata aaagcactat tttctgatag agtatactta gttgctgtgt aattgccagt
    20821 cttggtatag ccgatttgat tgcaggaatg agaagcttta ccagattcat agattttctc
    20881 ttctaagaaa gtaagaaggg gctcttcttg attgagattt atagcatatt tagaaataac
    20941 ttcaataggg ataaaagata aactataagc aatagcttta ttttggctat gataccagcg
    21001 atcaacaata atcacaacag gagtttcttg ttttagggat gctgtaatgg caacagtggg
    21061 cacttcaatc cgatattcca attcaacctt tgtgatgtca gatgataggc ttgcatatat
    21121 ggggtgttga agatattcga aaccttggtg atatttagtt tcaggagtct tgagtataaa
    21181 atttcccttt cctctgatat tttttatgag atgatcctct tggaggaggg ctagggattt
    21241 acgcagtgtc atccgactga cattgagctg tctagcaagt tcaggttctg atggcagttg
    21301 catgccagga ctatatgtac catcttgaat aagttgaaaa atagtattat atacttgcac
    21361 atgtttaagt tttttgagtt ttttggttaa gtcgttagta gacatatcac ttacctcatt
    21421 aataatcttt agtggagttt aacttgtcta aaaactattt tagcactaac agtattcctt
    21481 gattagaatt gtacccatct atagtgttag tatctcacac tcaggtactt tttgtcaaaa
    21541 aagagatgaa aaacacctta aaaaagcgtt tacaaaatag agtgtgtgtg atactataca
    21601 agtgtatcaa aaattagaca agtaaaatac aggaggtttt taacatgcaa aattattcag
    21661 gtgaagtcgg attgcaatat cacctacaga ttcgtccagg tgatgtaggt cgttatgtta
    21721 tcatgccagg tgatccaaaa cgttgtgcaa aaattgcaga acattttgat aatgcagttc
    21781 ttgtagcaga cagccgtgaa tatgttacgt atacaggtac attaaacggt gaaaaagtta
    21841 gtgttacttc aactggtatt ggtggtccat cagcgtctat tgcgatggaa gaattgaaac
    21901 tctgtggcgc tgataccttt atccgtgttg gaacatgtgg tggtattgac cttgatgtta
    21961 aaggcggaga catcgttatt gcaactggag ctatccgtat ggaagggacc agtaaagaat
    22021 atgctccgat tgaatttcct gctgtagctg acttggaagt gacaaatgct ctagttaatg
    22081 cagctaaaaa gcttggttat acaagtcacg caggagtagt tcaatgtaaa gatgcatttt
    22141 acgggcaaca tgagccagaa cgtatgccag ttagttatga attattaaat aaatgggaag
    22201 catggaaacg tctgggaaca aaagcgtctg aaatggaatc tgcagctctt tttgtagcag
    22261 caagtcatct aggagttcgt tgtggatcag atttccttgt tgttggtaat caagaacgca
    22321 acgctttggg tatggataac ccaatggctc atgatacaga agcagctatt caagttgctg
    22381 ttgaagcact ccgcacactt attgaaaatg ataaatcaca ataagcgagg ttttggaagt
    22441 catcatgcaa tttatttata gtattattgg tattttattg gtattaggaa ttgtgtatgc
    22501 aatttctttc aatcgtaaga gtgtttctct aagtttaatt ggaaaagctc ttatcgttca
    22561 attcattatt gcgctaatct tagtacgtat cccactaggc caacaaattg ttagtgttgt
    22621 ttcaactgga gttactagcg taatcaactg tggtcaagct ggtttaaatt ttgtgtttgg
    22681 gtcattagca gatagtggcg caaaaactgg ttttattttc gctattcaaa cgcttggtaa
    22741 tattgttttc ttatctgcct tagttagtct actttattat gtaggaatcc ttggatttgt
    22801 agtaaaatgg ataggtaagg gcgttggtaa aattatgaaa tcctcagagg ttgagagttt
    22861 tgttgccgta gctaatatgt ttcttggtca aacagacagt ccaattttgg ttagcaaata
    22921 cctaggtcgt atgactgata gtgagataat ggttgtgttg gtatcaggta tgggaagtat
    22981 gtcagtttct attcttggtg gctatattgc attaggcatt ccaatggaat atctcttgat
    23041 tgcttcaaca atggttccta ttggcagtat tctcattgct aaaatcttat tgcctcaaac
    23101 agaacctgtt caaaaaattg atgacattaa gatggataat aaaggtaata acgccaatgt
    23161 gattgatgca atcgctgagg gtgcaagcac aggtgcacaa atggctttct caattggggc
    23221 tagtttgatt gcctttgttg gtttagtttc tttgattaat atgatgttaa gtggattggg
    23281 aattcgctta gaacaaatct tctcatatgt ttttgctcca tttggttttc ttatgggatt
    23341 tgaccacaaa aacattcttc tagaaggaaa ccttcttgga agtaagttga ttttaaatga
    23401 gtttgtttcg ttccaacaat tgggtcacct aatcaaatct ttagattatc gtacagcatt
    23461 ggtagcaact atttcactct gtggttttgc taatttatca agtttaggta tttgtgtttc
    23521 aggtattgct gttctttgcc cggagaaacg tagcacccta gctcgacttg ttttccgtgc
    23581 aatgattggt ggtattgctg taagtatgct tagcgccttt atcgtcggta ttgtaactct
    23641 attctaaacg ttgacaaaag aaagaaggat agtaacgtgg aagtaaaaga tattttaaaa
    23701 acggtagacc atactttgct agcaacaaca gcaacgtggc cagaaatcca aacaatttta
    23761 gatgatgcca tggcttatga aacagcttca gcatgtattc cagcttctta cgtcaaaaaa
    23821 gcagcagaat acgtttcagg taaattagct atttgtactg ttattgggtt cccaaatggc
    23881 tatagtacaa ctgcagcgaa ggtttttgaa tgtcaagatg ctattcaaaa tggtgctgat
    23941 gaaattgaca tggtcattaa tttgacagac gttaaaaatg gggattttga tactgttgaa
    24001 gaagaaattc gtcaaatcaa agccgcatgt caagaccata tcttaaaagt tatcgttgag
    24061 acatgtcaat taactaaaga agaacttatc gaactttgtg gagttgtcac acgttcaggt
    24121 gcagacttta ttaaaacctc tactggtttt tcgacagcag gtgctacatt tgaagatgtt
    24181 gaagtgatgg caaaatatgt cggcgaaggt gttaaaatta aggcagcagg tggaatctca
    24241 tcattggaag atgctaaaac atttattgct ttaggagctt cacgcttggg tactagccgt
    24301 atcatcaaga ttgttaagaa cgaagctaca aaaaccgata gctattaact taatcatacc
    24361 gatttagctt gagactaaaa caaaaaactc atataatagg agttaaaaag cctactatct
    24421 tagtgataat aggctttttt agctatgaag acttccctgc gatccatcct gaacaaagag
    24481 ctgaggtaat attaaaccct ccggtgtgag cattaatatc taagacctct ccagcgaaat
    24541 acaggccagg aactttcttg ctttccaagg ttttagggtt gatttctttt aaatctacgc
    24601 ctcctttggt cacaaatgat ttagccaaag acatttttcc tgtaatgggt atctggaggt
    24661 gtttgagttt atcaagcaat tccttttctt gttttggaga gagttgtttg accttttcgg
    24721 ggtaatcttc tgataaaaaa tcagctactc gttcaggcag taggccttta agagcatttt
    24781 tgatgttttt atcacgttga tcactcagat aagcggttaa gtcatctgtt gataagtgtg
    24841 gcaaaaagtc cagctctgca atttctccac ctttcacaaa agaggacaga cgaagagctg
    24901 caggtcctga aaggccaaag tgggtgaaga gtaagtcgtg tgtgatgacg tgtttgtcat
    24961 aactaagagt aacgtcgtct agggaaatac cttgcaagac tttgtgagga aaatcagtta
    25021 acagagggct ctcagcagct tctaaatcag tcacggtcag tttaaaatgc cgtgcaatat
    25081 catgtccaaa acctgttgaa cccgttgaag ggtaggactt gcctcctgtg gtcacaatca
    25141 atttttggca ggtgaaagtc tggtctgtag atttgaggta gaagaggtca tcttgttttt
    25201 taacggaaac cacttcagtg ctggttagca cctgaccccc aagagccttg atttttttct
    25261 ccagagcatc aatgattgtc cttgatttat ctgttgtggg gaacatccgt ccatggtctt
    25321 cttctttgag tttgacgccg ttttcctcga aaaaggcaat gatgtcatgg ttgtcaaact
    25381 gggaaaaaac actatataaa aagcggccat tcccaggaat gcctgccata aggtcatcaa
    25441 ggttaccact attagtgaca ttacagcgtc caccaccggt tcccgctaat tttttaccta
    25501 agcggcgatt tttttcaatt aagagagttt tatagccata gtagctgctg gagatggcgg
    25561 ccatcatacc agcagggcca cctccaataa taatcgtatc gtattgagtc atagccttat
    25621 tttagcataa aagcgggggg tttaatagtc aggtaaatga actaacctgg cataccgttt
    25681 ttttacgtat ctaaacaatg cctccatgac atcaaaaagc tagaaaaata gtccagatga
    25741 ttaaaattat ctttttatga aaacggttgc ttttttattt aattcatgct attgtatt
//
LOCUS       DATWVB010000021        25345 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.021, whole genome shotgun sequence.
ACCESSION   DATWVB010000021 DATWVB010000000
VERSION     DATWVB010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25345
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.021"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(292..669)
                     /locus_tag="VCX65_001042"
     CDS             complement(292..669)
                     /locus_tag="VCX65_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEP5053507.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGEDFQEAYEMAVEVLG
                     FALEDYTDYPKASAVSDLKEQYPDSDIALIGIDMVAYMKKYHSKKVRKNVTIPEWLND
                     AAEDKNLNFSQVLTEALELKLQA"
     gene            complement(721..906)
                     /locus_tag="VCX65_001043"
     CDS             complement(721..906)
                     /locus_tag="VCX65_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEP5053508.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPMHNK
                     DLGKGLEDTILKQAGLK"
     gene            969..1436
                     /locus_tag="VCX65_001044"
     CDS             969..1436
                     /locus_tag="VCX65_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEP5053509.1"
                     /translation="MRIKYTKGGDGKLSKLTLKQKRFADEYIISGNAMESAIKAGYSH
                     NYSKAQSHKLLENVGIKEYLDERFEKMDSKTIADQKEVLQYLSSVMRGEQQEKTLISI
                     GELGQEIVDIDVGAKDRLKAAELLGKRYRLFTDKIEAEVQGTVVFVNEDDIPD"
     gene            1414..2721
                     /locus_tag="VCX65_001045"
     CDS             1414..2721
                     /locus_tag="VCX65_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEP5053510.1"
                     /translation="MKTTYQTKPKLEIKVDLPKTIGIGYGAFWRSKNFYRVVKGSRGS
                     KKSKTTALNFIVRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNQLKVTHLFKFNES
                     LPEITVKATGQKILFRGLDDELKITSITVDVGLLCWAWFEEAYQIETEDKFSTVVESI
                     RGSLDAPDFFKQITVTFNPWSERHWLKRVFFDEETKRADTFSGTTTFRVNEWLDDVDK
                     RRYEDLYKTNPRRARIVCDGEWGVAEGLVFDNFEVVDFDVEKTIQRVKETSAGMDFGF
                     TQDPTTLICVAVDLVNKELWLYNEHYQKAMLTDHIVKMIRDKNMHKSYIAADSAEKRL
                     IAEIKSKGVSGIVASLKGKGSIMQGVQFMQGFKIYIHPSCEHTIEEFNTYTFKQDKEG
                     NWLNEPIDKNNHVIDAIRYALEKYHIRSNESNQFEVLRAGFGY"
     gene            2733..4235
                     /locus_tag="VCX65_001046"
     CDS             2733..4235
                     /locus_tag="VCX65_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP5053511.1"
                     /translation="MYTESFRDSTGKTKTLEFRFHREARMRYQAESLESLLTEKYKLL
                     REMIEHHDKVQKPRIQELLDYAEGNNHTISEIGRRKDDDMADVRAVHNYGKYISTLKQ
                     GYLVGNPIRVEYIDGTEQQQDLLKDLSVKNNFHQLNRRLVKDLSKVGRAFELIYRSMD
                     DKTEVVRLDPREVFVIYQNNLEQSSLAGVRYYNKNQLDGTTKIVELYTDNKILKFEYD
                     GDLTLIREASSHAFGSVPITEYLNTDDGMGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIFGRVSFPHDVQTAEQRIEFVKVMRKARLLNLEPPVDQDGREGSVDAKYLYKQY
                     DVQGTEAYKNRIVSDIHKFTNTPDMTDSKFAGQQSGEALKWKVFGLDQERVDMQALFE
                     QSLKRRYKLIARVSQLLKEIDDFDISKLKITFTPNLPKSLQEKIEAFKALGGELSQET
                     AMAITDIVEDAKKEISLINSESKSRSQLAQKLEETSRLTDRELAHDHQKE"
     gene            4216..5778
                     /locus_tag="VCX65_001047"
     CDS             4216..5778
                     /locus_tag="VCX65_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEP5053512.1"
                     /translation="MTTRKSKYWRDRIKKEMDAKEADDISLEQSMKQLHDYHFRNIEK
                     EIESFYQRYADKEKIDLSEARKRASELDISAYQKKAKELIAKAEKLRKEGRTVTKADF
                     THQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKKFLDEGYRKEVEFQA
                     GLLGLSVASQANVKNLADAVINANFKGAKWSDNIWDRQDKLRSIISQSVQSAILKGKN
                     GLTIARDIRREFDVSASYAKRLAITEHARVQMEVGRLSMAENGFAMFDILPEPKACDV
                     CKDIAKHGPYHLDKWRIGENSPPFHPYCRCAVVGLDKKQEEKVNDKSEKFENITPNLM
                     PLFSKFASKITDLQRKIVYSADLADTGYIRTPHAFDINNTLRNKGYNYLNVDDKLITD
                     TLDSVISINSTPKNIKVYRFDDFELLGSINEQNNNIFDSGNFMDKLNQGGLSYTNDGY
                     TSASYDVKKNVMGYRPIKTEIKVPKGSHVYLTDNEEESEIILPRGTKYDIINAKINEY
                     EEIEITMEIRKE"
     gene            5782..5967
                     /locus_tag="VCX65_001048"
     CDS             5782..5967
                     /locus_tag="VCX65_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053513.1"
                     /translation="MDFSDFLNKKQKEWDESHPIPDFSAMSDEELLYQPMSEALVSER
                     FAKELSKEVRKRNLLSK"
     gene            6037..6351
                     /locus_tag="VCX65_001049"
     CDS             6037..6351
                     /locus_tag="VCX65_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053514.1"
                     /translation="MNRESKPGMESVKIGGLTYSVEKASDLQGKDGNWGLIHYKTQQI
                     KLDDSLTEQLEDQTLIHEIVHGILVEAGYTNHEEDQANRIGLILYQVLQDNDFSWLYK
                     GE"
     gene            6354..6620
                     /locus_tag="VCX65_001050"
     CDS             6354..6620
                     /locus_tag="VCX65_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053515.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAIQAKALRNQNKQIAELRAIIQ
                     QNVQAINREFVTAKNTILDNQLAIKLIGDDVGHIKQNYKRKWRK"
     gene            6764..7297
                     /locus_tag="VCX65_001051"
     CDS             6764..7297
                     /locus_tag="VCX65_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEP5053516.1"
                     /translation="MAEETQVVEMVEEQVVPEAKQPQDEKKYTDADVDAIIDKKFAKW
                     KSEQEAEKSEAKKMAKMNEKEKADYEKQKLLDELQELKNDKTRNELTAVARQMFAESE
                     INVNDDVLGLVVTLDAEQTKANVTTLANAFAKVIADDRKALVRQTTPSTGGGLRKQTN
                     YGANLASKAAQQSTKLF"
     gene            7307..7687
                     /locus_tag="VCX65_001052"
     CDS             7307..7687
                     /locus_tag="VCX65_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEP5053517.1"
                     /translation="MNKRKVTTSKEILHNLDYEAISVTLDSKKIGKEVVPAGTVLAGV
                     SGSVFEDRKQKVKAVDNSAVESEDNICGILLTDVDLTNGDAVGSCIYRGTINADKLAD
                     SSIAGKYEVLEEELPHIVFIKGGK"
     gene            7690..8772
                     /locus_tag="VCX65_001053"
     CDS             7690..8772
                     /locus_tag="VCX65_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEP5053518.1"
                     /translation="MALIHEIITSENIKGFYNAKNENVGNTLGENAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMTVELLDEEMPFFKEAMVVKEADRQQLSLLAQ
                     TKNQELIDTALAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPDTKWEQVDTATPLKDIEKAIEVMAERGFVPEAIIMNSKTLSLIKNASNTLD
                     VVKPMAPDGAAVTKGDLETYIADELGLKILLKDGMFVGDDGKAKKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLLGGEATDAEVSIVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIINATESEEETKKENSFEM"
     gene            8782..9024
                     /locus_tag="VCX65_001054"
     CDS             8782..9024
                     /locus_tag="VCX65_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053519.1"
                     /translation="MPRVIRAFKDKVTKVVYEVGDIYSGDRVEFLTEGGVLEPSVDFD
                     KLKVSEIKSKLDELSIEYDAKLKKSELLKLLKQTIG"
     gene            9038..9391
                     /locus_tag="VCX65_001055"
     CDS             9038..9391
                     /locus_tag="VCX65_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEP5053520.1"
                     /translation="MDAVNTSSVISNVKLDLGILDSQQDDLLNMLLKRVTDHFKAKYG
                     AVEIDSAFSFVLEDCLIARFNRRGAERAKSESVEGHTTTYYDFLDEFEPYDAMIMAKL
                     NLIKDKSRKGGLYFL"
     gene            9388..9696
                     /locus_tag="VCX65_001056"
     CDS             9388..9696
                     /locus_tag="VCX65_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053521.1"
                     /translation="MRYADRVTFVKTTDEQYNPDLGEYTHTEVISITKPCFVMDMGME
                     KSVQIFGDYQKDRKVIYLKQPYTKAFDYCEYEGKRYKAQANKLGAIVFYLEGDDSIGG
                     "
     gene            9677..10042
                     /locus_tag="VCX65_001057"
     CDS             9677..10042
                     /locus_tag="VCX65_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEP5053522.1"
                     /translation="MILLVADISLKVVGTAGLKKKLELIVKKDAVKKIVRDNGTQLQR
                     KMINKAVFTKGYSTGATRRSITMQIGDGGLSVKVKPGTHYAGYLERGTRLMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            10039..10428
                     /locus_tag="VCX65_001058"
     CDS             10039..10428
                     /locus_tag="VCX65_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEP5053523.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVELMLSVWGVQKKRKQVSDMASAIFSQAMSVARTDGFCWSFNIRQ
                     SSIQMLDDTTTVTPLKRAIVTLRFNLR"
     gene            10483..11106
                     /locus_tag="VCX65_001059"
     CDS             10483..11106
                     /locus_tag="VCX65_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEP5053524.1"
                     /translation="MSKAQEQTKQLEAKQGIHSILLFRLLKEASSEVATKLAFQTEHE
                     VGKSRDVDGQKTKDGIIQSVGALEYDFKATSILAKGDELAAKLEKAMEDGELVEIWDI
                     DSEEISKNGDSDNKLAKVWGINKNGTNGGNGKCLATYYQGYISSFSAKKNAEENIVIE
                     MEFAINGVGKKGFATLTDAQKAAVQYAFKDTTKSNSEETKKENSFEM"
     gene            11160..11513
                     /locus_tag="VCX65_001060"
     CDS             11160..11513
                     /locus_tag="VCX65_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEP5053525.1"
                     /translation="MQLEIKGKTHNVKFGTRFVAEMDKNHIAERQGFKFGAGLQSSVP
                     FLIDHSVVTLAEVIYTGTITEPPRPSLNDIYDYIDEVEDIEKLFDDVLDELRQSNASK
                     LFMAQVEKDLAEAKA"
     gene            11588..11884
                     /locus_tag="VCX65_001061"
     CDS             11588..11884
                     /locus_tag="VCX65_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053526.1"
                     /translation="MTDINEIGRLTLYEYDLLMTGKALAAVDESHKAHKQAWINHQVT
                     ATKLVGGKKNKKEVPVYKKFKDFFDYEEEIRKITQEIDEGYDKKGMDLLLKANL"
     gene            11899..15534
                     /locus_tag="VCX65_001062"
     CDS             11899..15534
                     /locus_tag="VCX65_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEP5053527.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLQSAIRSIEGLEKRSTGFSSVSQ
                     KASSMFKSMLGANLAGQAISAMTRTVSSGLGSMLGEMNSSAKAWKTFDANLADIGFGK
                     KQILAAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKSMGKNLDELVADIQAGRVK
                     TSDFLEAVKKAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKVDFSKFASNLGKFLEGINIDKIVSNISSAISSVTSKVKEFWDGFKQTGAI
                     SAFSGALQSVWEALKNVASAMSGGNWKTFGATVGGTVKHVSNFAKAVSDVLGKMDPGR
                     LRSWIATFAAVAGGFKLFEKLTGQSVIGSFLDKIGSKFGLFGNKAKEGTDKASNGARR
                     SGGIISQIFSGLGNIVKSAGTAISTAAKGIGAGIKTALSGIPPIISSLGTAISTVAQG
                     IGTGLAIAFKGLGSAIAMVPPTTWLALGAAILMVGAAFALAGTQADGISQILRTVGDV
                     VVQILQQVTDSLATLLPIIANAIGSMLPIVAGAISQIVGAVAGGLSQLVIAVSTGASL
                     VIGAFTGLLGGISGVINSISAVIQSLTGVITAVFNGIATVISSVGSAIKDVLTGLGTA
                     FEGFGNGVKSALEGVGAVIESFGSAVRNVLDGVANILDSMGTAALNAGRGVKEMAKGI
                     KMLVDLSLGDLVATLAAVASGLGKMASSAGEMTTLGSAMSKVANGMTRLATSATIAIT
                     GLTVFATTMATIKTAVATLPPVLTMAASGFTTFTTQAVAAVTGLAAINAPITMFKAQL
                     MTITPALAQAGAGFAAFVAQSSTFSTGLASAGPTIAAFNANLMSLSATTGALVASIAG
                     LSAVLSVVSAGFSQIGASATATVGQIQAFASSTTVVSSAFASMQSMIQSAMAAIVSSI
                     ITSFNQAASQMQSILSRMLSQARTFGSQLEQQMRQSGQRSGQNLARGLSSQQSAVINA
                     ISSMVNAAVSRANAGAGPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARA
                     KAMIHSPSRLFAKRVGQYIPQGVAMGIDKNADVVDDSVGGLFDSINSFDFNIADRLAS
                     IGAKFQGVIKSESSQSLSQQQEFVHTAQPAYINFSLGGNEYEAFVSDITNQQAKIEKI
                     RLKRSSW"
     gene            15566..16345
                     /locus_tag="VCX65_001063"
     CDS             15566..16345
                     /locus_tag="VCX65_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEP5053528.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDVVDLEHQTTSVLGRNGEYFHNATVEVRKLEIKAKITGKDNQSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDVPEEVSNEQIIGLTFICYNPFKMSDVKTKKGTS
                     IQNGGLFQTKPIITLNLSSPTKEIKLLHVESQKYIRLTGTYTTDEIKIDMATGKITQN
                     GRNILGDLDMINSRYFELLPGNNTLQCANAAITAEFREVYL"
     gene            16342..18396
                     /locus_tag="VCX65_001064"
     CDS             16342..18396
                     /locus_tag="VCX65_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP5053529.1"
                     /translation="MIYLFDKLERLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     VEPFVYFGFFNYDPNQKEDVFKLFKVIDYNLEDSKFYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGITNVRTLSYYYISPRAALIKIVEAFNCEFNVRY
                     TFINNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     HEEAEPKDVEGHLPQEERRQGYGRRIEFTDVVWSVEKGDPIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKTELLKATWEELQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNRESRSRKEAVQNMI
                     DESLETITDLGMTFQEFLQGIEKRIETGKKEMEDNWRKVNLEFDNFKKKVEQEGLQFN
                     TLKEQIKEVDERTDKELEEFRATLKNLALPEEAIKKITEAIKVDDIPSLKQNFDDLKN
                     KVSETSETARLNAEIIGTDGKTRYNKNLLVGDPNRVKTYDQDYIEVEANDGGFKRGET
                     YTISFSQTCELLKKVAITLTQINNKGVKLVLTPTKAKMDAQTFEVTKDKQSIEVYPLS
                     YTGVLTGDWYKSKSVEINASEAQELALEMAYKEIADAKGATIIGKQSDKPKIILDGRR
                     DR"
     gene            18393..19607
                     /locus_tag="VCX65_001065"
     CDS             18393..19607
                     /locus_tag="VCX65_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053530.1"
                     /translation="MTSVETIPIKIVFDRKDASEWQSTNPVIDEGELVVELDTHKLKV
                     GDGKTSYNDLPYYEGPQGESITKVQLSENGDLSVWIGDKETKLGNIKGQKGDKGTSIT
                     DITKDGETLTIKLSDDTQKIFNIPNGQKGDRGKGVESARIDESGHLKLKIEEESELDL
                     GNVKGESGPKGDSITITNHKRVSDGTQVSFSDGTQIVVPKGDTGDVNGINLEDYVKKS
                     ELKNVGSADVKAINDFLGLSQKVFTSSYSYTDSLLKSYAKPSYSASWYVNESTVSTKN
                     GDKVLITIHNTTTQADNYLEVAVTYVGANYVTATSTGRLLTTPGEVKVVTKKQAEKDY
                     AAKKHKHEISDIAGLNERLSGYLRQADIQSQLNNIGKLKDTQTGQYLEVKVVDKGQVP
                     SNTSGMIVFERS"
     gene            19594..19923
                     /locus_tag="VCX65_001066"
     CDS             19594..19923
                     /locus_tag="VCX65_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053531.1"
                     /translation="MRGHNLLKDLNNIIINNKTIDRIICNNTIVYQRSWDLLFDGLLT
                     SAGKKLDIYPFYKIVINNAFFVKTPTTKNNTIFLAGHKILALQDSHFCFFRALEKSFF
                     VKIYGKN"
     gene            19934..21829
                     /locus_tag="VCX65_001067"
     CDS             19934..21829
                     /locus_tag="VCX65_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEP5053532.1"
                     /translation="MSRDPTLLIDESNLTIGSDGRAYYTFTADGDTKSVKIANNKCIG
                     TTRFNQLMIERGGKPTNYVAPVVVEGTGNPTGLFKDLKEISLELTDTKNSKLWSKIKL
                     NNQGMIEEYYNGTIKSEIIKTAEGTQQRISSETDKKLALINETVSGIRREYQDADRQL
                     SSSYQAGIEGLKATMANDKIGLQAEIQTTAQGLYQRYDNEIRKLSAKITTTSSGTTEA
                     YESKLDGLRAEFTHSNQGMRVELESKISGLQSTQQATARQISQEISNREGAVSRVQQG
                     LDSYQRRLQNAEGSYSSLQQTVSGLQSDVNSPNSKLNSRISQLASQIDQRVTRADVTS
                     IINQSGDSIKLAIQRAGGIDAKMSAKEIVSAINLNGYGVRISGERIALDGNTTVNGAF
                     GAKIGEFIKLKADQIIGGTIDANKINVINLNASSIVGLDANFIKARIEYAITSLLEGK
                     VIKARNGAMTIDLQSGQINHYTNESAMRRIDSSTASQFIKMTKSGFISEIGNMQAAMT
                     VIGSNSDGSENHENKTFGGIRIWNGKSSYQSTSFVELVGNRVAIYGNKNRSPWLFDST
                     TSGYAYLIPQNESGIKHAIGRADRKIDQIHVGDIYVQGERVAMMLKDLANRIGYIGTG
                     GWANRIG"
     gene            21843..22004
                     /locus_tag="VCX65_001068"
     CDS             21843..22004
                     /locus_tag="VCX65_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053533.1"
                     /translation="MQEKLLGKIINDLTLKVANLTLENAQLKAQHEIELEELNAQLDE
                     ATAPKEEGK"
     gene            22007..22624
                     /locus_tag="VCX65_001069"
     CDS             22007..22624
                     /locus_tag="VCX65_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053534.1"
                     /translation="MRNWKVTGNYPQWDGTGAVIDTQVIITDDRGAVIAEKIKKDLRT
                     ANDAEIIEAALEEFKKTAYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHMLTSGGKIDPDIYKGMLELIEPAKKGEYQAYDVFTVVDSTKEED
                     GEAGEGNLVFVHVNEPFTYEAQTLKDLESEDKVTVIKYADLVKQD"
     gene            22635..22931
                     /locus_tag="VCX65_001070"
     CDS             22635..22931
                     /locus_tag="VCX65_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053535.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANEFAMAQLKD
                     SIKELAYELKNLDREREITKKIIDRHEERLGRVEDEVIINKERIITLFKKGEEK"
     gene            22928..23113
                     /locus_tag="VCX65_001071"
     CDS             22928..23113
                     /locus_tag="VCX65_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053536.1"
                     /translation="MNNWFKKVAIKTIKTMAQTAVGLIGSSMLITDINWPTMLSAVLL
                     SGLTCILMNVSQIKEEE"
     gene            23225..24559
                     /locus_tag="VCX65_001072"
     CDS             23225..24559
                     /locus_tag="VCX65_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEP5053537.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLRTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            complement(24635..25342)
                     /gene="speC"
                     /locus_tag="VCX65_001073"
     CDS             complement(24635..25342)
                     /gene="speC"
                     /locus_tag="VCX65_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021733756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeC"
                     /protein_id="HEP5053538.1"
                     /translation="MKKINIIKIVFIITVILISTISPIIKSDSKKDISNVKSDLLYAY
                     TITPYDYKDCRVNFSTTHTLNIDTQKYRGKDYYISSEMSYEASQKFKRDDHVDVFGLF
                     YILNSHTGEYIYGGITPAQNNKVNHKLLGNLFISGESQQNLNNKIILEKDIVTFQEID
                     FKIRKYLMDNYKIYDATSPYVSGRIEIGTKDGKHEQIDLFDSPNEGTRSDIFAKYKDN
                     RIINMKNFSHFDIYLEK"
BASE COUNT         8586 a         4367 c         5585 g         6807 t
ORIGIN      
        1 tctattcttt agtaagactg atactgattt aatttcaatt ttagtagttt caagttggtt
       61 gagctcaaca gtaatgatgt tcctaagttc gttctttgtg ctaagaacat taattttgtt
      121 agttgaaact tataataatt tcaaaaataa ataggtcatc acattgtggt gacttttttg
      181 ttatggtcca cgacatggtt acttattagt tacaaacgtt gaaattacaa tgtttcgata
      241 ggtcaacgtc gtggtttttt attatgtaaa aaagaaccac aacagtggct cttatgcttg
      301 taattttaat tcaagcgctt cagtaagaac ttgagaaaag ttgaggtttt tatcttctgc
      361 tgcgtcgttt aaccattcag ggatagtcac gtttttgcgg acttttttgg agtgatattt
      421 tttcatatag gcaaccatat cgatgccaat taaagcaatg tcggaatcag gatactgttc
      481 ttttaaatca gaaacggcgc tagcctttgg atagtcagta tagtcttcaa gggcaaaacc
      541 taagacttcg acagccattt cataagcctc ttgaaagtct tcaccttgag taattgcttc
      601 aggtacatct ggaaatgtaa ccatgatata gtctgtgtct tgtgtaaatg tagctggata
      661 aattaacata atgatcctcc tttgattact gtgagataag cacaccatct ggcaagcgga
      721 ttattttaaa cccgcctgct ttagaatggt atcttcaaga ccttttccga ggtctttatt
      781 gtgcattgga acaatggttt gatgtccgtt attgtctcgg aattttttgt gacttccgtt
      841 ttgactgact tcgtagaacc cattcttttt tagcagtttt atcatctgct ttggggtcat
      901 tggcatattg cttacctcac tttctatact tatattatac acataaacaa tgtagatgtc
      961 aatgcaaaat acgcataaaa tacacaaaag gcggtgatgg aaaattgagt aaattaacac
     1021 taaaacagaa gcggtttgca gatgaataca tcatctcagg gaatgctatg gagtcagcta
     1081 taaaggctgg gtatagccat aattattcca aagcacagtc gcacaagcta ttggaaaatg
     1141 ttggaattaa agagtatctt gatgaacgat ttgaaaaaat ggattccaag acaatagcag
     1201 accaaaaaga ggtattgcaa tatctttctt cggtcatgag aggtgagcag caagaaaaaa
     1261 cactcatcag cattggagag cttgggcaag aaatagttga tattgatgta ggagcaaaag
     1321 acaggttgaa agcagctgaa ttgcttggta agcggtacag attgtttacc gataagatag
     1381 aggctgaggt gcaaggaacg gtggtgtttg tcaatgaaga cgacatacca gactaagcca
     1441 aagctagaaa tcaaagttga tttacctaaa actatcggta taggttatgg cgctttttgg
     1501 cgctctaaaa atttttatcg agtagttaaa ggcagccgtg gatctaaaaa atctaaaacg
     1561 actgctttaa attttatcgt cagactgctg aagtaccctt gggctaactt attggtcatc
     1621 cgtagatact caaacactaa caaacaatct acttataccg attttaaatg ggcgtgtaat
     1681 caattaaagg ttacacacct ttttaagttt aatgagagct tgccagagat aaccgtcaag
     1741 gcaacaggac aaaaaatctt attccgtggt cttgatgatg aactcaagat aacatctatt
     1801 actgttgatg tcggtttgct ctgttgggca tggttcgagg aggcttatca aattgagacc
     1861 gaagataagt tttcaacagt tgtcgaatca atccgcggta gtttagatgc tcctgatttt
     1921 tttaaacaaa taacagtcac gttcaacccg tggtcagaaa gacattggct taagcgtgtc
     1981 ttttttgacg aagaaactaa acgggccgat acattttctg ggactacaac atttagagta
     2041 aacgaatggc ttgatgatgt cgataaaaga cgctacgaag atttgtacaa gactaatcca
     2101 aggcgggcta gaatcgtctg tgatggtgaa tggggcgttg ctgaaggtct tgtttttgat
     2161 aactttgaag tcgtagattt tgatgttgaa aaaacaattc aacgtgtcaa agagacttca
     2221 gctggtatgg actttggttt tactcaagac cctacaactc ttatatgtgt tgcagttgac
     2281 ctcgtaaaca aagaattatg gctttacaat gaacattatc aaaaagctat gttgacagat
     2341 catattgtca aaatgataag agataaaaat atgcataaat cttatatcgc agctgatagc
     2401 gctgaaaaac gtctaatagc agagataaaa agcaaaggtg tatctggtat tgttgccagt
     2461 cttaagggta aagggtctat tatgcaagga gttcagttta tgcaaggttt taaaatatac
     2521 atccaccctt cttgtgaaca cacaatagaa gagtttaata cttacacttt taagcaagac
     2581 aaagaaggta attggttaaa cgaaccgata gataagaata accacgttat tgatgcgatt
     2641 agatatgcgc ttgaaaaata ccatatcaga agcaacgagt caaatcagtt tgaagttctt
     2701 agggctggtt ttggttacta gaaaggaaaa taatgtacac agaatcattt agagatagta
     2761 cgggaaagac taaaacatta gagtttaggt tccaccgtga agctcgcatg aggtatcaag
     2821 cggaaagtct agaaagcttg ttaaccgaaa aatataagct actccgtgaa atgattgaac
     2881 accacgataa agtccaaaaa ccacgcatac aagagcttct agattatgca gagggaaata
     2941 accacaccat cagcgaaata ggccgtagga aagacgatga catggctgat gttcgtgctg
     3001 tgcataacta tggtaagtat atttcaacgc tcaaacaggg ctatttggtg ggtaatccta
     3061 ttcgtgtaga gtatattgat ggtaccgagc agcagcaaga cctattaaag gacctatctg
     3121 ttaaaaacaa tttccaccag ctgaaccgca gattagtaaa agacctatcc aaggttggtc
     3181 gagcgtttga attgatttat cgcagcatgg atgacaagac agaggtcgtt agactagatc
     3241 cacgggaagt atttgttatc tatcaaaata acctagagca atcaagctta gctggtgtgc
     3301 ggtactataa caaaaatcaa ttagatggta ctacaaaaat tgtcgagctt tacaccgata
     3361 ataaaatcct gaagtttgaa tatgatggtg atttaacact gattagggag gcttcgtctc
     3421 atgcgtttgg ttcggtacca atcacggagt atctcaacac agatgacggc atgggcgact
     3481 acgagacaga gttgtcttta atcgacttgt atgatgcagc tcagtctgat acagctaact
     3541 acatgcaaga tttgtcagac gcaattctag ccattttcgg acgtgtgtca tttccgcatg
     3601 atgttcagac agccgaacag cgtatcgaat ttgtgaaagt gatgcgtaaa gctagattgc
     3661 ttaacctcga gcctcctgtc gaccaagacg ggcgtgaggg atctgtagat gccaaatatc
     3721 tatataaaca atatgacgta caaggaaccg aagcctataa aaatcgtatt gtgtccgaca
     3781 tccataaatt taccaatacg ccagacatga cagacagtaa gtttgccggt caacaatccg
     3841 gagaggcgtt gaagtggaaa gtgtttggtc ttgatcagga gcgtgtcgac atgcaagctt
     3901 tatttgagca atctcttaaa cgtaggtaca aactaatcgc tcgtgtaagc caactgctta
     3961 aagagattga tgactttgac atcagcaagc ttaaaatcac atttacgcca aacctaccta
     4021 agtcgctaca agaaaagatt gaagccttta aagcattggg tggagagttg tcgcaagaga
     4081 cagctatggc tattacagac atcgtggaag atgctaagaa agaaattagc cttatcaata
     4141 gcgagtcgaa atcacgtagt caactagcgc agaagttaga agaaaccagt agattgactg
     4201 atagggagtt agctcatgac caccagaaag agtaaatact ggcgtgaccg tatcaagaaa
     4261 gaaatggatg ctaaagaggc agacgatatc tctcttgagc aatccatgaa gcaattgcac
     4321 gattatcatt tcaggaatat cgaaaaagaa attgagtcgt tttatcaacg ttatgctgac
     4381 aaagagaaaa tagacctttc agaagcccgt aagagagctt ctgagcttga tatttctgct
     4441 taccagaaga aagctaagga acttattgca aaggctgaga agctacgaaa agagggtaga
     4501 acggtaacaa aagccgactt cactcatcaa gaaaatgcag acatggctat ttacaactta
     4561 gccatgaaaa ccaacgcttt agaattgttg cgcttgaata tcgacttgga gatgcaagaa
     4621 cttgccaacg gcgaacacaa gctaaccaag aaatttcttg acgaaggtta ccgtaaagag
     4681 gttgagttcc aagctgggct attaggatta tcagttgcta gccaagcgaa tgtgaaaaac
     4741 ttagctgatg ccgttattaa tgctaatttc aagggagcaa aatggtcaga taacatttgg
     4801 gacagacaag ataagttacg tagcatcata tctcaaagcg tccaaagtgc tatcctaaaa
     4861 ggtaaaaatg gcttaactat tgcaagagat attagacgag agtttgatgt gtcagcatct
     4921 tacgcaaagc gactagcgat aacggagcat gcaagggttc agatggaagt tggtagatta
     4981 tccatggcgg agaatggctt tgctatgttt gatatattgc ctgagcctaa agcatgtgat
     5041 gtttgcaagg atatagctaa gcatggtcca tatcaccttg acaagtggag aataggggaa
     5101 aactctccgc cgtttcatcc gtattgtcgt tgtgcagttg taggattgga taagaaacaa
     5161 gaagaaaaag tgaatgataa atctgaaaaa tttgaaaaca taacaccgaa tctcatgcca
     5221 ttatttagta agtttgcaag taaaataaca gatttgcaac gtaaaatagt gtactctgct
     5281 gatttagcag ataccgggta cattagaaca ccgcatgcgt ttgatataaa caataccttg
     5341 cgaaataaag gctacaatta tctaaacgtt gatgataaac taattaccga cacattggat
     5401 agtgtcatct cgataaattc aactcccaaa aatataaaag tataccgatt tgatgatttt
     5461 gagttattag gttcaatcaa cgaacaaaac aataatattt ttgattcagg taattttatg
     5521 gataaattaa accagggagg attatcatac accaacgatg gatatacttc tgcaagttat
     5581 gatgttaaaa aaaacgtgat gggatatcgt cctattaaga ctgaaataaa agtacctaaa
     5641 ggaagccacg tttatcttac agataatgag gaagaaagtg aaattatact accacgaggg
     5701 acaaagtatg atataattaa tgcgaagata aatgaatatg aagaaataga aatcactatg
     5761 gaaataagaa aggagtaagc gatggatttt tctgattttt tgaataaaaa acaaaaagag
     5821 tgggatgaat ctcatccaat tcctgacttt agtgcaatga gtgatgaaga attgctttat
     5881 cagccaatga gtgaagcttt agtgtctgaa agatttgcta aagagttatc taaagaggtt
     5941 agaaagcgta atttattatc aaaataaaaa catattatta tagacggaag actgtggtcg
     6001 cccgtctttt tttgtaccca aaaacaggag gaaaacatga atcgtgaaag taaaccaggt
     6061 atggaaagcg taaaaatcgg agggttgaca tactctgttg aaaaggcatc ggacctgcaa
     6121 ggcaaagatg gcaattgggg tcttatacac tacaaaacac aacaaattaa actagatgac
     6181 tcattaaccg agcagctcga agatcaaaca cttatccacg aaattgttca tggaatttta
     6241 gttgaggcag gctatactaa tcacgaagag gaccaagcta atcgcattgg tctgattttg
     6301 tatcaagtat tgcaggataa tgattttagc tggttgtaca aaggggaata aatatgaata
     6361 aacgcatcaa gaaaaaacgt aagttagaaa cagcagttgt gatgcttgtt gcagaaaatg
     6421 ctatacaagc aaaagctctt agaaatcaaa acaaacaaat tgcagagctg agagcgatta
     6481 tacaacaaaa cgtccaagca ataaatagag agtttgtaac tgctaaaaac acgattttag
     6541 ataaccaatt agctattaag ttaattggtg atgatgttgg tcacatcaag caaaattata
     6601 agcggaagtg gcgaaaataa attttaaact ggtcgaattc gaccccttta gaatcaaact
     6661 aagtcgtagg aatacggttt ttttattatg tccaagcatt gacgacgata aaagctatgg
     6721 aattaataat cggggacgat ttaaaacata ggaggtgcca atcatggcag aagaaacaca
     6781 agtagttgag atggttgaag agcaagtggt acctgaagca aaacaaccgc aagacgaaaa
     6841 aaagtataca gatgcagatg tggacgctat catcgacaaa aagtttgcga aatggaagtc
     6901 agaacaagaa gctgagaaat cggaagccaa gaaaatggct aagatgaacg agaaagagaa
     6961 agcagactac gaaaagcaga agctgttaga cgaattgcaa gaactaaaaa acgataagac
     7021 acgcaatgag ttaacagcag tagctcgtca aatgtttgca gaatctgaaa tcaacgtcaa
     7081 cgatgacgta cttggtttag ttgtgacttt ggacgcagaa caaacaaaag caaatgtaac
     7141 aacgctagca aacgcatttg ctaaagttat cgctgatgac cgcaaggctc ttgtacgcca
     7201 gaccactccg tcaacaggcg gtggattgag gaaacaaacc aattacggtg ctaacttggc
     7261 tagtaaggca gcacaacaaa gcaccaagct tttttaggag gaaattatga acaaacgtaa
     7321 agtaacaaca tctaaagaga ttctacacaa tctcgactat gaagctattt cagtaacttt
     7381 ggattcaaaa aaaatcggca aggaagttgt tccagctggg acagtgttag caggtgtttc
     7441 aggatcagta tttgaagacc gcaaacagaa agttaaagcg gtcgataaca gtgccgtaga
     7501 aagtgaggat aacatctgcg ggattttgct tacagatgtc gatttaacaa atggcgatgc
     7561 agtcggttcc tgtatttatc gtgggactat caatgcagac aagcttgctg attcatctat
     7621 tgcgggaaaa tatgaagtgt tggaagaaga actaccgcac attgtcttta tcaagggagg
     7681 taaataaaca tggcattgat tcacgaaatt atcacatcgg aaaatatcaa aggtttttac
     7741 aatgctaaaa acgaaaatgt cggaaacacg ctaggggaaa acgcatttcc cccaaaacaa
     7801 caattaggac tcaaactttc gtttattaaa ggtgcagcag gcaaacctgt cacacttaaa
     7861 gcggcagcct ttgatacaaa agtgccacta cgtgaccgta tgactgttga attactcgac
     7921 gaagaaatgc cattcttcaa agaggctatg gttgtcaagg aagcagaccg tcaacaactc
     7981 agtttgttag ctcaaactaa aaatcaagag cttattgaca cagcgctagc agcgatttac
     8041 aacgataaag taacacttat tgcaggtgca aaagcacgtc tagaagcaat gcgtatggaa
     8101 gtattgtcta aaggtaaaat ccatgttgca tcaaacggtg tcatgaaaga ttttgattat
     8161 gggttagatt cttcgcaaac aactaagcca gatacaaaat gggaacaagt agataccgct
     8221 acaccactta aagacatcga aaaagctatc gaagtaatgg cagaacgtgg ctttgtgcca
     8281 gaagctatca tcatgaactc taagacactt agcctgatta aaaatgcaag taacacttta
     8341 gacgttgtaa agcctatggc gccagatggg gcagctgtta ctaaaggtga tttggaaact
     8401 tatattgctg atgaattagg tcttaaaatt ttgcttaagg atggaatgtt tgtcggagac
     8461 gacggtaaag ctaaaaaata cttcccagat ggatttgcaa ctttagttcc taacggcaat
     8521 cttggttaca cagtatttgg tactactcca gagcaatcag atttgcttgg tggtgaggca
     8581 acagatgctg aggtctctat tgttgaaaca ggtattgcaa ttaccactac taagacaact
     8641 gacccagtga acgtccaaac aaaagtttct atgattgctt tgccatcgtt tgaacgcttg
     8701 gaagaagtac aaatcattaa tgcaacagaa tccgaagaag aaactaaaaa agaaaacagc
     8761 tttgaaatgt aggaggtcaa tatgcctaga gtaattagag catttaaaga taaagtaaca
     8821 aaagtagtct acgaagtcgg cgatatttac tcgggcgacc gagtagagtt tttgacagag
     8881 ggtggtgttt tagaaccgtc cgtagacttt gacaagctga aagtgagtga gattaaaagc
     8941 aaacttgacg agttaagcat tgagtatgat gctaaactta aaaaatccga gctattgaag
     9001 cttttaaagc aaacaatcgg atagtttgga ggtgtttatg gatgcagtaa acacaagtag
     9061 cgttataagc aatgtaaagc ttgatttagg catcttagac agtcaacagg acgatttact
     9121 taacatgttg ctaaaacgcg ttacagacca ttttaaagct aaatatggcg ctgtcgaaat
     9181 agacagcgct tttagttttg ttttagaaga ttgtttaatt gctagattta accgtagagg
     9241 tgccgagagg gcaaaaagcg agagtgtgga aggtcatacg acaacatact acgacttttt
     9301 ggatgagttt gaaccttacg atgccatgat tatggcaaag cttaatttaa tcaaagacaa
     9361 atctcgtaaa gggggactgt actttttatg agatatgcag atagagttac atttgttaaa
     9421 acgacggatg agcaatacaa tcccgattta ggtgagtata cgcacacaga ggtcataagt
     9481 atcacaaaac cttgttttgt gatggacatg ggcatggaaa agtccgtaca gatttttgga
     9541 gattatcaaa aggatcgtaa agttatctac ctgaagcagc cttatacaaa agcatttgat
     9601 tattgcgagt atgagggcaa gagatacaaa gcgcaggcaa ataagcttgg cgctattgtt
     9661 ttttatctgg aaggagatga ttctattggt ggctgatata tctttaaaag tagttggaac
     9721 agctggttta aaaaagaaac ttgagcttat tgtcaaaaaa gatgccgtca agaagattgt
     9781 cagagacaat gggacgcagc ttcaaaggaa aatgattaat aaagcggtat ttacaaaagg
     9841 ctattcaaca ggtgcaacta gacgttctat taccatgcaa atcggcgatg gtggattgag
     9901 tgtcaaggtt aaaccaggaa ctcattatgc cggctacctt gaaagaggaa ctcgccttat
     9961 gagcaaacaa ccgtttgttt tgccagctct aaaagagcaa aaagtaaaat ttagaaaaga
    10021 tttggaggcg cttgtcaaat gattaaaact agagatcagt ctatttttga cgaaatgttt
    10081 aaacgcatcc agtctttagg ttttaaggtt tacgattata aaccgatgac ggaagttcca
    10141 tatccatttg tggaaatgga atctactgat gcggaatata ttccaaataa agatgacatt
    10201 aaaggttctg ttgaacttat gttgtctgtt tggggggtgc agaaaaaacg gaagcaggtg
    10261 tctgacatgg catctgctat tttttcgcaa gctatgtccg tagctcgtac cgatggattc
    10321 tgttggtcgt ttaatattag gcagtcgtct atacagatgt tagatgatac aacaactgtg
    10381 acacctctta aacgagcgat tgtcacactt agatttaatt tgagatagga ggtagtaatg
    10441 tcagaaccta gcaaagcaac aacacaggag gagaaagaag taatgtcaaa agcacaagaa
    10501 caaacaaaac aattagaagc aaaacaagga attcattcaa tcttgttatt tcgtttgttg
    10561 aaagaagcat ctagtgaggt agcaactaaa cttgcttttc aaacagagca tgaagtaggt
    10621 aaaagccgtg acgtagatgg acaaaaaact aaagatggta ttatccagtc cgtgggggct
    10681 ttggagtacg actttaaagc aacatctatt ttagccaaag gtgacgaact agcagctaaa
    10741 ctagaaaaag ccatggagga tggtgagctt gtagaaattt gggatattga ttcagaagaa
    10801 ataagcaaaa acggcgacag cgacaataag cttgcaaaag tttggggtat taataaaaat
    10861 ggaacaaacg gaggaaacgg taaatgccta gcgacttatt accaagggta catttcaagc
    10921 ttcagcgcta agaaaaacgc agaagaaaat attgtaattg aaatggagtt tgccatcaat
    10981 ggtgttggta aaaaagggtt cgctacatta acagatgccc aaaaagcagc tgtacagtac
    11041 gcatttaaag atacaacaaa atccaacagc gaagaaacta aaaaagaaaa cagctttgag
    11101 atgtaacggt taggttggat ttagtatcca accttttatt tttaaaggag aaaagaataa
    11161 tgcaattgga aattaaaggt aaaactcata acgtaaaatt tggtacacga tttgttgccg
    11221 agatggacaa aaatcatata gcagaacgtc agggatttaa atttggagct ggtctacaat
    11281 ctagcgttcc gtttttaatc gaccacagcg ttgttactct tgcggaagta atttatacag
    11341 gtacaatcac cgaaccacca cgtcctagtt tgaatgatat ttacgactat attgacgaag
    11401 ttgaagatat tgaaaagctt tttgatgatg ttttagacga actacgtcaa tcaaacgcat
    11461 caaagttgtt tatggctcag gtggaaaaag acctggcgga agccaaagcg taacaaatat
    11521 aaaaaagagt tattcttctc aagaaagctt tgagacgatt gtgcttaatt gcattagata
    11581 ccttggcatg actgacatca atgaaatcgg gcgattaact ttgtatgaat atgatttatt
    11641 aatgacaggc aaagcactag cggctgttga tgaatcacat aaagctcaca aacaagcttg
    11701 gataaaccac caagttacgg caacaaagct tgttggtggc aagaaaaata aaaaagaagt
    11761 ccctgtttat aaaaaattca aggacttttt tgattatgag gaagaaatcc gaaaaatcac
    11821 tcaagaaatt gatgaaggtt acgacaagaa aggtatggat ttacttctca aagctaacct
    11881 ttaaggaaag gaggttaaat gggagaatct tattctgttg aagcggtttt gacagctgtt
    11941 gataaaacct ttggcaaaac attacaatcg gcaatccgtt caatcgaagg cttggaaaag
    12001 cgttcaaccg gtttttcatc ggtgtctcaa aaagctagtt ccatgtttaa atccatgtta
    12061 ggagcgaatt tagccggaca agctatctcg gcaatgacaa ggacagtgtc atcaggcctt
    12121 ggctctatgc ttggcgagat gaatagttca gcgaaagcgt ggaaaacttt tgacgccaat
    12181 ttagcggaca ttggatttgg aaaaaaacaa attttggcag ctaaaacggc gatgcaagac
    12241 tatgcaacta aaacaatcta ctcggcatca gatatggcta gcacgtatgc acagttagca
    12301 gcggttggcg tgaaagatac cggaaagctc gtaaaagctt ttggcggttt agctgcatct
    12361 gctgaaaatc cgaagcaggc catgaagtct atcagtcaac aaatgacgca agcagtagga
    12421 agaccaacag ttgcatggca agactttagg ataatgctgg aacaggcgcc tgcagggatg
    12481 gctaaagtcg ctaaatctat gggtaaaaat cttgatgaac tcgtcgccga tatccaggcg
    12541 ggtagggtta aaaccagcga ttttttggaa gcggtaaaaa aagcaggcaa tgataagagt
    12601 ttccaaaaga tggcaactga gttcaaaact gttgaccaag ccatcgacgg tatgcgagaa
    12661 ggcttatcca acaaattgca accagcgttt gaaaaagtga accaatttgg aattagagcg
    12721 atcgaagcaa tcggtaaaca actcgataaa gttgattttt ctaagtttgc tagtaatctt
    12781 gggaaattcc ttgaaggaat taatatcgat aaaattgtat ctaatatttc atcggcgatt
    12841 tcatctgtca cttcaaaggt taaagaattt tgggacggtt tcaaacaaac tggagcaatt
    12901 agtgcttttt caggagcttt gcagagcgtt tgggaagctt taaaaaatgt cgctagcgcc
    12961 atgagcggag gaaattggaa gacttttgga gcaacagttg gagggactgt taaacacgtc
    13021 tctaacttcg ctaaagctgt ttccgatgtt ttaggaaaga tggaccctgg cagactaaga
    13081 agttggatag ctaccttcgc cgcagtagct ggaggcttta aattattcga aaaattaacg
    13141 gggcaaagcg tcattggttc ttttttggat aaaattggca gcaaatttgg cctctttgga
    13201 aacaaagcca aagaaggaac agacaaagcc tctaacggcg ctagaagaag cggtggcatt
    13261 attagccaaa tcttcagcgg cttgggtaat atcgttaagt ctgctggtac agccatatca
    13321 acagctgcaa aaggtatcgg agctggtatt aaaactgctt tgtctggaat cccccctatc
    13381 attagttctc taggaaccgc aatatcaaca gttgcgcaag gtataggcac tgggctagca
    13441 atcgcattta aaggccttgg ttctgctatt gccatggtgc cgcctaccac atggctagct
    13501 ttaggagcgg caattttaat ggttggtgct gcttttgcct tggcaggaac tcaagctgat
    13561 ggcattagtc aaattttaag aaccgttggc gatgttgttg tgcaaatctt acaacaggtc
    13621 actgatagtc tagccacttt actacctatt atcgcaaacg ctattggctc tatgttgcca
    13681 attgtagctg gagctatctc tcagattgta ggcgcagtag cgggcggatt atctcagctc
    13741 gttatagccg tttcaacagg ggcatctctc gttatagggg ctttcacagg acttcttggt
    13801 ggtatttctg gggttattaa ctccattagc gctgttatcc aatcgctaac tggtgtgatt
    13861 accgcagtat tcaatggcat agctactgtt atttcatctg tcggttcggc tatcaaagat
    13921 gtattgacgg gtctaggaac cgcttttgaa ggatttggaa atggtgtaaa atcagctcta
    13981 gaaggtgttg gggcagtaat tgaatcgttt ggtagtgcag ttaggaatgt ccttgacggt
    14041 gttgcaaata tccttgattc tatgggtact gcggcactta atgcaggccg tggcgtaaaa
    14101 gagatggcta aaggcattaa aatgcttgtt gatttatccc ttggagattt ggttgctaca
    14161 ttagcagctg tggcaagcgg tctagggaag atggctagct cagctggcga aatgacaaca
    14221 ttaggttctg ctatgagcaa ggtagccaat ggtatgacac gtctagcaac aagtgctacg
    14281 atagcaatta ctggattaac agtctttgcc accaccatgg caactattaa gacagcagtt
    14341 gcaactctac cgccagtcct aacgatggca gcgagtgggt ttaccacatt tactactcag
    14401 gcggtggcag cagtgactgg attggctgca attaatgctc caatcactat gtttaaagct
    14461 caactaatga caataacacc agctctagca caagctggcg ctggctttgc cgcgtttgtt
    14521 gctcaatcat caacatttag tacaggttta gcatctgccg gtcctacaat agcagcgttc
    14581 aatgctaatt tgatgagctt atctgcaaca acaggagcgc tagttgcatc aatagctggt
    14641 ttatcagctg tgctttctgt tgtatcagct ggctttagcc aaataggggc ttctgcgaca
    14701 gcaactgttg gtcaaataca agcttttgct tctagtacaa cagttgtttc gtcagcattt
    14761 gctagcatgc aatctatgat tcaatctgcc atggctgcaa tagtaagcag cattataaca
    14821 tcatttaatc aagcggcctc tcaaatgcaa tcaatcttat ctcgaatgct atctcaggct
    14881 aggacatttg ggtctcaact agagcaacaa atgagacaat cgggacagcg ttcaggacaa
    14941 aatcttgctc ggggactatc ttctcaacaa agtgctgtta ttaatgctat ttctagcatg
    15001 gttaatgctg cggtatcaag agccaacgcg ggagctggtc ctatgcgtca agctggagcg
    15061 tacatcggac aagggcttgc gcaaggaatg tattcagcgc taggagctgt aacagctgca
    15121 gcaaacgccc ttgtagcaca agccgagaga gcagcaagag ccaaggcgat gattcattcg
    15181 ccgtcaaggt tgtttgcaaa acgagttggt caatatatcc cgcaaggggt agctatgggt
    15241 atcgacaaaa acgctgatgt cgttgacgac tctgttggcg ggttatttga tagcatcaat
    15301 agctttgatt ttaatatcgc agatagactg gctagcattg gagctaaatt ccaaggtgtt
    15361 atcaaatcag agagttcaca atcgttatcg cagcaacaag agttcgtaca tacagctcaa
    15421 ccagcgtata taaactttag tttaggtgga aacgaatacg aagcatttgt aagtgacatc
    15481 actaatcaac aagcaaaaat tgaaaaaatc agactaaaga gaagcagctg gtagttgttt
    15541 ctcttagttt tttgaaagga gtaaaatgta cgaatttaac gatactatca gaggtactcc
    15601 gaaagttact tttaatttaa agacaacaat tggtgaaaag gtattagaag aagaactcaa
    15661 taatgattta ggtaccttta ggacattgac tgtttctggt cgtgatgtgg tggacttaga
    15721 gcatcaaaca acaagtgttt tagggcgaaa tggtgagtat ttccacaatg ccacagtcga
    15781 agtcagaaaa ctagaaataa aagctaaaat cactggaaaa gataaccagt caatgcgttt
    15841 gcaatatgaa aaattaaaca gattaattgt tagtcacaat caagtttttt tatcattttc
    15901 agacgaacct gacagaaatt atctaggcat ctttaaatct aaagatgtcc cagaagaagt
    15961 ttctaacgag cagattatag gactaacatt catctgctac aatccgttta aaatgtctga
    16021 tgtaaaaact aaaaaaggaa catctatcca aaatggtggg ttatttcaaa caaagcctat
    16081 catcactctc aacctatcat caccaacaaa agaaattaaa ttgttgcatg tcgaaagcca
    16141 gaagtatatc agattgactg gaacttatac cactgacgaa atcaagattg atatggccac
    16201 gggtaaaatt acccagaacg gtcgcaacat ccttggagat ttagatatga ttaatagtag
    16261 gtattttgag ctattacctg gtaataatac attacagtgt gccaatgccg ccataaccgc
    16321 agagtttaga gaggtttatc tatgatatac ctgtttgata aacttgagcg attggtcgct
    16381 actgttggta ctgatgactt gctctcatgg cactttaagg tcaaaaacaa tgattgggac
    16441 caggctagtt ttgaagtgcc agttgattat gacgtagagc catttgtcta ctttggtttt
    16501 tttaactacg accctaatca aaaagaagat gtctttaagc tctttaaagt cattgattac
    16561 aacctagaag atagcaagtt ttacaaaggc ttagacaaag ctgagagtga tcttgatacc
    16621 attgccatta tcaaagataa gcgctttaga caatcgtccg cagatgcttg tattgatggt
    16681 gctttagagg gtacgggtta tcaagttggc aaagttgagg gaataacaaa tgttagaaca
    16741 cttagttatt actacatcag tccacgagcg gctctgatta agattgtgga agcttttaac
    16801 tgcgagttca atgtcaggta tacctttatt aataacaaaa tcactagtcg ttatatcgac
    16861 ctcaaaaagc gctttggaaa gccaacaggc aagcaatttg aacatggcaa caacctgtta
    16921 aaagtcgtct acgaggaatc aacagatgac attgtgactt gtctgattgg cagaggtaag
    16981 ggtgaggaaa tccaacacga agaagctgag cctaaagatg tcgagggaca cttgccacag
    17041 gaagaaaggc ggcaaggcta cggtcgaaga atcgaattta ctgatgttgt ctggtcggtc
    17101 gaaaaaggcg acccgataga caaaccagct ggtcaaaact ttgtagcact agatagtgca
    17161 agggaagaat acggcttgtc tcaaaatggt gagctaaaac accgctgggg tgtctttgtc
    17221 aatgaggaaa tcgaggataa gacagaactc ttaaaagcaa cttgggaaga attgcagcgt
    17281 ttgtcaatcc ctatcagaat ttacaaggca gaaatcttag acattggtcc agagacgtgg
    17341 aaaggcgact cagtagccat tatctatgat gaggtaaaaa tagcttttga aactcgggtt
    17401 gatgagattg atattgacaa gcttaatttt aacaggtcag tcgtaacact tggtgattac
    17461 agcgttgtcc aaaatcgtga gtcacggtct cgtaaagagg ctgtccaaaa catgatagat
    17521 gaatctttag agactatcac agacttagga atgacatttc aggaattttt gcaaggcatc
    17581 gaaaaacgca tcgagactgg caaaaaggag atggaagaca attggcgaaa agttaacctt
    17641 gaattcgata actttaaaaa gaaggttgag caagaaggct tgcaattcaa caccttgaaa
    17701 gaacaaatca aagaagttga tgaacgcacc gacaaagagc tagaggaatt ccgagccacc
    17761 ctcaaaaacc tagcgttacc agaggaagcg attaaaaaaa tcacagaggc tatcaaagtt
    17821 gatgacatcc cgtctcttaa gcaaaacttt gatgacttaa aaaacaaggt cagcgagaca
    17881 agcgagacgg cacgtctaaa tgccgagatt atcggtacag acggtaagac ccgctataac
    17941 aaaaatttat tggttggcga ccctaaccgt gtaaaaacct atgaccaaga ctatatcgag
    18001 gtagaagcta atgatggcgg ctttaagcgt ggcgagacct acacgattag ctttagtcaa
    18061 acgtgtgagc tactcaaaaa agtagctatc acattgacgc aaattaacaa caagggagtt
    18121 aagttagtac tgacaccaac caaagcaaaa atggatgcac agacgtttga ggtcactaaa
    18181 gataaacagt ctatagaggt ttatcctttg agctatacag gcgttttaac aggtgattgg
    18241 tataaatcta agtctgtgga gataaacgcc tcagaggcgc aggaattagc tcttgagatg
    18301 gcttataaag agattgcaga tgccaaaggt gcaactatta tcggcaaaca gtccgataaa
    18361 ccaaaaatta ttttagatgg gaggagggac agatgacatc agtcgaaaca ataccaataa
    18421 aaattgtctt tgaccgaaaa gacgcttcag aatggcagtc aactaaccct gtcattgacg
    18481 aaggtgaact agtcgtcgag ctagacaccc ataagctaaa ggtcggagat ggtaaaacaa
    18541 gctacaatga cttgccttac tatgaaggtc cgcaaggaga atccataaca aaagtacaac
    18601 tatccgaaaa tggtgacttg tctgtgtgga ttggcgacaa agagactaag cttggcaaca
    18661 tcaaaggtca aaaaggggac aaagggacaa gtataaccga catcaccaaa gatggtgaga
    18721 cactcactat caaactatca gacgacactc aaaaaatctt taatatcccc aatggccaaa
    18781 aaggggatag aggtaagggc gtagagagcg ctaggattga cgaatccggt catttaaaat
    18841 taaaaattga agaggaatca gagttagatc ttggaaacgt taaaggtgag tcaggaccta
    18901 aaggtgatag tattactatc acaaatcaca agcgtgtttc agatggaacg caggtatctt
    18961 tcagcgacgg gacacaaatt gttgtcccaa aaggggatac tggtgatgtc aacggcatca
    19021 atctggaaga ttatgtcaaa aaatctgaac ttaaaaacgt cggttctgca gatgttaaag
    19081 ctattaatga ctttttaggg ctatctcaaa aggtgtttac aagcagctat agttatacag
    19141 atagcttact aaaaagttat gcaaaaccca gctattcggc gagttggtat gtcaacgaat
    19201 ctacagtttc taccaaaaat ggtgacaaag tattgattac aatacataac actaccaccc
    19261 aagcagacaa ttatttggag gtagcggtga cttatgttgg tgctaactac gtgactgcta
    19321 cctcaacagg tcgcttactg actactcctg gtgaagtcaa agtagtgaca aaaaagcaag
    19381 cggaaaaaga ttatgctgct aaaaaacata agcatgagat tagtgacata gctggtctta
    19441 atgagcgctt gtctggctat ctcagacaag ctgatataca gtcacagctt aataatatcg
    19501 gtaagctaaa agacacgcaa accggacaat atcttgaggt taaagtggtt gataaaggac
    19561 aggtgcctag caataccagt ggcatgatcg tgtttgagag gtcataattt gttaaaagat
    19621 ttaaataata tcattattaa taacaaaacg attgatcgta ttatttgtaa taatacgatt
    19681 gtctatcagc gttcgtggga tctgcttttt gacggtttgc tgacaagcgc tgggaaaaaa
    19741 ttggatattt atccttttta taaaatcgta atcaataatg cattttttgt taaaaccccc
    19801 acaacaaaaa acaatacgat ttttttagca gggcataaaa tactagcatt acaagatagt
    19861 catttttgtt tttttagagc attagaaaaa agtttttttg tcaaaattta cggtaaaaat
    19921 taggaggtaa catttgagta gagacccaac acttttaata gacgagtcaa atttaacaat
    19981 cggctcagat ggacgtgctt attatacatt tacggctgat ggtgacacaa aaagcgttaa
    20041 aatagccaat aacaaatgta tcggtacaac tcgctttaac cagctcatga ttgagcgagg
    20101 gggtaaacca actaactacg tggcgcccgt ggttgtcgag gggacaggta atccgactgg
    20161 actatttaaa gacctcaaag agattagcct cgagttaaca gatactaaaa actccaaact
    20221 ttggtcaaaa atcaagctta ataatcaagg gatgattgaa gagtattaca acggtacaat
    20281 aaaatctgag attatcaaaa ccgcagaggg cacgcagcaa cgtattagta gcgagaccga
    20341 taaaaaactt gcgcttatca acgagacagt ctcaggcatt agacgtgagt accaagatgc
    20401 agatagacag ctatcgtcaa gctaccaagc tggtattgag gggctaaaag ccacaatggc
    20461 caatgataaa atcggtttac aagctgagat acaaacaacc gctcaaggct tgtatcaaag
    20521 gtatgataac gagatacgca agctgtccgc taaaataacc actacctcgt caggcactac
    20581 agaggcctat gaaagcaagc tcgatggctt acgagctgag tttactcata gtaatcaagg
    20641 tatgcgcgta gagctggagt caaaaatcag tgggttgcaa tcaacgcaac aagcaactgc
    20701 caggcaaatc tcacaagaga taagtaaccg tgaaggtgct gtcagtcgtg tacaacaggg
    20761 cctagacagt tatcagcggc gattacaaaa tgctgaaggg agttacagca gcttacaaca
    20821 aactgttagt ggtttacagt ctgatgttaa tagtccaaac agtaagctta attctcggat
    20881 tagccaatta gctagtcaaa ttgaccaacg agtcacaaga gccgatgtga caagcatcat
    20941 taaccagtct ggggacagta tcaagttagc catacagaga gctggtggga ttgatgctaa
    21001 gatgtccgca aaagagattg tctcagccat aaacctcaat ggctacggtg tcagaatttc
    21061 tggtgagcgt attgctttag acggcaatac cacggttaac ggggcttttg gcgcaaaaat
    21121 tggtgagttt atcaagctaa aagccgacca gattatcggt gggacaatcg atgcaaacaa
    21181 aatcaatgtg attaatctca acgctagcag tattgttggt ttagacgcta attttattaa
    21241 agcaaggatt gagtatgcga tcacaagttt gcttgagggt aaagttatta aggctcgtaa
    21301 tggtgcgatg acaatagact tgcaaagcgg tcaaatcaac cattacacaa atgagtcagc
    21361 catgagacgt atcgatagca gtacagctag tcagtttata aagatgacaa agtcaggctt
    21421 tatatctgag ataggtaaca tgcaagctgc aatgacggtt ataggctcta atagcgatgg
    21481 gtcagaaaac catgaaaata aaaccttcgg aggcataaga atttggaacg ggaagtcatc
    21541 ttatcaatcg acaagttttg ttgaattagt cggtaaccgt gtagcaatct atggaaataa
    21601 aaatcgtagt ccatggctct ttgactcaac aacgtcagga tatgcttacc tcattccaca
    21661 gaatgaaagt ggtataaagc atgccatagg gagagctgat cgtaagatag accaaatcca
    21721 cgttggagat atctatgtgc aaggcgaacg tgtcgctatg atgttaaaag atttagcgaa
    21781 taggattggc tatataggta caggtggctg ggctaaccgc ataggataaa ttaggagaaa
    21841 caatgcaaga aaaattatta ggaaaaatta ttaacgattt aacacttaaa gtcgctaatt
    21901 taacgctgga aaatgctcaa ttaaaagcac agcatgaaat cgaattggaa gaattaaacg
    21961 cacaattgga tgaagcaaca gcaccgaagg aagaaggtaa ataaacatga gaaattggaa
    22021 agtaacagga aactacccac agtgggacgg tacaggagca gtcattgata cgcaggtaat
    22081 tattacagat gacaggggtg cagtcatcgc agagaagatc aaaaaagatt tgagaacagc
    22141 taatgatgca gaaattatcg aggctgcttt agaggagttt aaaaagactg cttacgtcga
    22201 aatcgctatg ggcgaagccg tgcaaaaagt agacgacctt gaaaaaatct cacaggaaac
    22261 tgctaagact gccaaaactg ctcaaacagc tgctggacta gctaaggtgt ccgcagagcg
    22321 cacgcaaaag atgattaact tacaaacgat ccacatgtta acgagcggcg gcaagattga
    22381 tcctgacatt tataaaggca tgcttgagct aatcgagcca gccaaaaaag gtgagtatca
    22441 agcgtatgat gtctttacgg tggtcgacag tactaaagag gaagacggtg aagcaggcga
    22501 agggaaccta gtcttcgtac acgttaacga gccgtttact tatgaggcgc aaactcttaa
    22561 agatttggaa tcagaggata aagtcacagt cattaaatat gcggatttgg ttaaacaaga
    22621 ttagaggtgg ttagatgata gattttgtac aaattggtgc tttttgtggc gctgctttgt
    22681 ctatcttggg tgtttgggga tttatcgtca atccctttaa aaaagccatg gaagctaatg
    22741 agtttgccat ggctcaactc aaggactcaa ttaaggagtt agcttatgag cttaaaaatc
    22801 ttgatcgtga acgtgagatt accaaaaaaa ttatcgacag acacgaggag cgtttaggtc
    22861 gcgtagaaga cgaagttatt atcaacaagg agcgtattat tacgctattt aaaaaaggag
    22921 aagaaaaatg aataactggt ttaaaaaagt agcaattaaa acaattaaaa caatggcaca
    22981 aacggccgtt ggtcttatcg ggtcaagcat gttgattacg gatattaact ggccaacaat
    23041 gttgtcagca gtgctgttgt caggactaac atgtatcctg atgaatgtgt cacaaatcaa
    23101 ggaagaggaa taggtcatgc gagcaatcac acgattagca ttagttatag caatcgcaat
    23161 actgtatgtg ccattatctg tggttgcttt gattttttat ccatttttag ataaggaggg
    23221 ataaatggct acatatcagg aatataaaag tcgttcaaat ggcaatgctt acgatattga
    23281 tggatcgctt ggtgcgcaat gttgggatgg ctacgcagac tactgtaagt atctaggact
    23341 gccatacgca aactgtacaa atacaggata tgcaagggat atatgggaac aacgtcacaa
    23401 aaatggtatt ttaaactact ttgacgaagt agagactatg caagctggag atgtcgcaat
    23461 ttttatggta gttgcaggtg ttacaccgta tagccatgtg gctatttttg atagtgatgc
    23521 aggtagtgga tacggatggt ttttaggtca aaaccagggt ggagcaaacg gagcatataa
    23581 tttagtaaaa ataccatatt caacgactta tcctactgca tttagaccaa aagtttttaa
    23641 aaatgcagtt actgttatag gtaatatagg actaaataaa ggcgattatt ttattgatgt
    23701 atcagcttat caacaagcag acttaaccgc tacttgtcag caagctggca ctactaaaac
    23761 gattatcaaa gtatccgagt cactcgcttg gctgtctgat aggcatcagc aacaagctaa
    23821 tactagtgac cctattggtt attatcactt tggacgattt ggaggagata gcaacttagc
    23881 gcaacgagaa gcagatttat ttctgtccaa tttaccaacc aaaaaagtct cttacttagt
    23941 cattgattat gaagactctg caagtgccga caaagaagct aacactaatg cagttattgc
    24001 gtttatggat aaaattgcaa acgctggata taagcctgtt tattacagct ataaaccatt
    24061 tacgcttaat aatattgatt atcagcaaat tatcgctaag tacccaaaca gcatttggat
    24121 agctggttat ccagactacg aagtacgaac agagccactt tgggagttct tcccttcaat
    24181 ggatggtgtg cgctggtggc agttcacaag tgtaggagta gcaggtggtt tagataaaaa
    24241 tattgtatta ttagcagatg atagtagcaa agtggatata cctaagattg acaaaccaca
    24301 aagccagctt acttttaatc aaaagctaga tactaatact aaattagaca actcgaatgt
    24361 accttactac gaagcaaccc ttagaacaga ctattatgta gagtctaagc caaacgcaag
    24421 tagcgctgat aaagaattta tcaaggcagg aactcgtgta agagtctatg aaaaagtgaa
    24481 tggatggtca cgtattaacg cttctcagtc tgaccagtgg gtcgaagata agtatttatc
    24541 taatgcaaca caagtataaa ataggaggta aagctccttt agataagaca aaaccgctca
    24601 gataatttct gggcggtttt ttgtgtatga tgaattattt ttcaagataa atatcgaaat
    24661 gactaaagtt cttcatattg ataattctat tatctttata ttttgcaaaa atatctgatc
    24721 tagtcccttc atttggtgag tcaaataagt ctatttgctc atgtttccca tcttttgtgc
    24781 caatttcgat tctgccgctt acataaggag aagtagcgtc ataaatttta taattatcca
    24841 taaggtattt tctgatttta aagtcaattt cctggaaagt tacgatatct ttttctagaa
    24901 taattttgtt atttaagttc tgttgagatt ctcccgaaat aaatagattt cccaataatt
    24961 tatgatttac tttattattt tgagcaggcg taattcctcc atagatgtac tcaccggtgt
    25021 gagaattaag aatataaaat aatccaaaaa catctacatg atcatctcgt ttaaattttt
    25081 gagaggcctc ataagacatt tcggaactaa tataatagtc tttccctcta tatttttgag
    25141 tatcaatgtt taatgtgtgt gtcgttgaaa aatttaccct gcaatcttta taatcataag
    25201 gagttatagt gtatgcataa agtaaatcac ttttaacatt cgaaatgtct ttcttagagt
    25261 cacttttgat gataggtgaa atagtagaaa tcagtatgac tgtaattatg aaaactattt
    25321 tgatgatgtt aatctttttc atttt
//
LOCUS       DATWVB010000022        24624 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.022, whole genome shotgun sequence.
ACCESSION   DATWVB010000022 DATWVB010000000
VERSION     DATWVB010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24624
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.022"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(158..2422)
                     /gene="glgP"
                     /locus_tag="VCX65_001074"
     CDS             complement(158..2422)
                     /gene="glgP"
                     /locus_tag="VCX65_001074"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEP5053539.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(2457..3950)
                     /gene="malQ"
                     /locus_tag="VCX65_001075"
     CDS             complement(2457..3950)
                     /gene="malQ"
                     /locus_tag="VCX65_001075"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEP5053540.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEAADLCDITFGTNPEAVDYA
                     QLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKEYFNNKALQDW
                     DDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSALKTYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNGWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            complement(4066..5085)
                     /locus_tag="VCX65_001076"
     CDS             complement(4066..5085)
                     /locus_tag="VCX65_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP5053541.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESV
                     RDISH"
     gene            5328..6575
                     /locus_tag="VCX65_001077"
     CDS             5328..6575
                     /locus_tag="VCX65_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP5053542.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQILFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFN
                     GKIKESDYLTKLQQFDKDIAATK"
     gene            6849..8210
                     /locus_tag="VCX65_001078"
     CDS             6849..8210
                     /locus_tag="VCX65_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP5053543.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPNFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINAKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            8210..9046
                     /locus_tag="VCX65_001079"
     CDS             8210..9046
                     /locus_tag="VCX65_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP5053544.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            9204..10001
                     /locus_tag="VCX65_001080"
     CDS             9204..10001
                     /locus_tag="VCX65_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP5053545.1"
                     /translation="MTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHI
                     SNLLNYTPNQAARALVTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDYQLV
                     CLNEDSIEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYAA
                     LKDQANQFFKDEPYTLLSLPITNRERYEHVSAFFPSLHIVNDLRELTYFEKENLLLID
                     ESLDQFFVNSSQKLYCPRFSPKKGQVILEAIEWAKKRQPDKKHNLLV"
     gene            complement(10117..10932)
                     /locus_tag="VCX65_001081"
     CDS             complement(10117..10932)
                     /locus_tag="VCX65_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEP5053546.1"
                     /translation="MPDKKQFPISYISHCLSARAMFASRAQFTWWQNLLIIVFLNALI
                     MIPVTLHYANMTTYPLERIVTKSLSPITDKTYQALTQGKIEKDTFQGQSLIRRDGELV
                     LAVLPTKVDLEQLASESTRQIIVTKKEWRFVTPDGKELRAHVRGQQQSLADLTTVKAV
                     KDFVNQQWYDSNKASVLGFLLLTFVLMVCVGTLIVIGLGAFFLTLTKRSRLFMIRNFS
                     EGLGLMVNCLAWPSLLAIALSFFIQDPVLIMNCQVFGTLLMLTWVFYKTQFRD"
     gene            complement(10954..11814)
                     /locus_tag="VCX65_001082"
     CDS             complement(10954..11814)
                     /locus_tag="VCX65_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP5053547.1"
                     /translation="MRKTYVSISMKRKRFFTQLLTYLYLISLVIVILFPILVTVSSAF
                     RPGNTTAFSFHFDGPWTLSNFKTLFQDTLYLRWYWNTLIVAFFTMLIQVTVITLTGYA
                     YSRYNFFGRKKSLIFFLVVQMVPTMAALTAYFVMAWLFNALNQYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVLPLVRPMIAVQSLWAFMGPFGDF
                     MLAKFLLRAQENYTVAVGLQSFITNDARNPKVTLFAAGAILIAVPISVLFFFLQKNFV
                     SGLTSGGTKG"
     gene            complement(11811..13118)
                     /locus_tag="VCX65_001083"
     CDS             complement(11811..13118)
                     /locus_tag="VCX65_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP5053548.1"
                     /translation="MVDNQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLEL
                     LEIVVLGIPALTGFYSLGSVPMQDHSLFMLIKGAMQLITLVLFGIFHLVAMRDAKLVA
                     HQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
                     RHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIWTLAATSLQIVIGIATAVI
                     ANQSFIRGKRLFGVIFLLPWAVPAFISIMSFGNFFNDSIGAMNVQVLPFIEKFLPFVD
                     FGIVSWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQAIPADLYEAATVDGATVLQK
                     FRHITMPMIFAVAAPTFISQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYK
                     LTTQTSPQFSMASAVTLIISVIVISVSLITFKKFKAFDMEERS"
     gene            complement(13193..15328)
                     /locus_tag="VCX65_001084"
     CDS             complement(13193..15328)
                     /locus_tag="VCX65_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclomaltodextrin glucanotransferase"
                     /protein_id="HEP5053549.1"
                     /translation="MRELHIKTYKLLTKSAVLLGLISFPLTVSAADNASVTNKADFST
                     DTIYQIVTDRFNDGNTSNNGKTDVFDKNDLKKYHGGDWQGIIAKIKDGYLTDMGISAI
                     WISSPVENIDSIDPSNGSAAYHGYWAKDFFKTNQHFGTEADFQQLVKVAHQHHIKVVI
                     DFAPNHTSTAEKEGTTFKEDGALYKNGKLVGKFSDDKDKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNINPKVDQYMKEAIDKWLDLGVDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFVFGEWFSGHTDDDYDMTTFANNSGMGLLDFRFANAIRQLYTGFSTFTMRDFYKVL
                     ENRDQVTNEVTDQVTFIDNHDMERFATKVANNQTAVNQAYALLLTSRGVPNIYYGTEQ
                     YATGDKDPNNRGDMPSFNKESQAYKVISKLAPLRKQNQALAYGTTEQRWISDHVLVFE
                     RKFGNHVALVAINRDQTNGYTITNAKTALPQNSYKDKLEGLLGGQELIVGADGTISSF
                     ELGAGQVAVWTYEGEDKTPQLGDVDASVGIAGNKITISGQGFGNSKGQVTFGEISAEI
                     LSWSDTLITLKVPTVPANYYNISVTTADKQTSNSYQAFEVLTDKQIPVRLLINDFKTV
                     PGEQLYLMGDVFEMGANDAKNAVGPLFNNTQTIAKYPNWFFDTHLPINKEIAVKLVKK
                     DSIGNVLWTSPETYSIKTGHEAQTITIKK"
     gene            complement(15354..17057)
                     /locus_tag="VCX65_001085"
     CDS             complement(15354..17057)
                     /locus_tag="VCX65_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEP5053550.1"
                     /translation="MNVAGMLHIPDSRYCFAISQKELVIRLRVAKEDRGITVNLVHGP
                     KYGYHEFQEELEMSVAYTDHTHAYYETTLTLDDVRLAYIFKIEEEGQTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQVIPWTKDAVFYQIFVDRFNRGDWEKGDSYVNMGW
                     LEKPTPKSFAGGDLKGITEKLDYLKDLGITVIYLTPIFQSISNHKYDISDYYAIDPQF
                     GTKYDLQELIDLAHQMGIKIILDAVFNHASSDAVEFQDVLRYGKESKFFDWFMTHDEH
                     PSMDLVNYETFAGCNYMPKWNTSNRDVQDYLIEIGRYWIKEFCIDGWRLDVSDEVSHD
                     FWRRFRQAVKAEKADAILIGENWHDAYPYLAGDQYDGIMNYAFTKACLDYFAFETMTS
                     KQLAEKLSNILMRNTWQVNRMNLNLLDSHDTHRFFTQVKGSKDKLLAALALLFIFMGI
                     PCLYYGTEVAMEGGYDPDSRRGFPWDDAERDKDFFSKVKAIIALRQQPALQEGAISID
                     YDEDCLILKRSLGEQSISLVLNNGESAYSIKEGGQILTSNGVTKNKKQLLQDGYIVFS
                     N"
     gene            complement(17223..18482)
                     /locus_tag="VCX65_001086"
     CDS             complement(17223..18482)
                     /locus_tag="VCX65_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP5053551.1"
                     /translation="MSWNWKKASVLGTLSLASVLPLTACVSGGGKGVKETDGKTIVVS
                     VDEGYVDYIKSIKGEFEKEHKVTVKVKKEGMMDTLDKLSTDGPTGASPDVFLAPFDRV
                     GGLGTEGQISEVTLGNSKEFDDTVKKLVTIDGKTYGAPDVIETLVTYYNKDLVPQAPK
                     SFTELEVLQKDSKFAFASEPGKSVGFLAKWTDFYYGYGLIAGYGGYIFGDKGTKPSDL
                     GLGNDGTVEGLNYAKQWYGTWPQGMQDTKKAGDFITEQFISKKAGVIIDGPWAASSFK
                     DAGVNFGVMEIPTLTNGKKYQPFAGGKAWVISNYSKGKTTAQKFLDYVTNAENQKRFY
                     DKTQEIPANLTARNYASKEGNELTKAVISQFESAQPMPNIPEMAEVWEPGANMFFNVA
                     SGKEEASKAAKEAAKTIKEAIEQKYAE"
     gene            complement(19091..20074)
                     /locus_tag="VCX65_001087"
     CDS             complement(19091..20074)
                     /locus_tag="VCX65_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEP5053552.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGIQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTALQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDCEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEPT"
     gene            complement(20105..21355)
                     /gene="dltD"
                     /locus_tag="VCX65_001088"
     CDS             complement(20105..21355)
                     /gene="dltD"
                     /locus_tag="VCX65_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEP5053553.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(21348..21587)
                     /gene="dltC"
                     /locus_tag="VCX65_001089"
     CDS             complement(21348..21587)
                     /gene="dltC"
                     /locus_tag="VCX65_001089"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEP5053554.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(21605..22861)
                     /gene="dltB"
                     /locus_tag="VCX65_001090"
     CDS             complement(21605..22861)
                     /gene="dltB"
                     /locus_tag="VCX65_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEP5053555.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(22858..24396)
                     /gene="dltA"
                     /locus_tag="VCX65_001091"
     CDS             complement(22858..24396)
                     /gene="dltA"
                     /locus_tag="VCX65_001091"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEP5053556.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGEHRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELASGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(24408..24551)
                     /locus_tag="VCX65_001092"
     CDS             complement(24408..24551)
                     /locus_tag="VCX65_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEP5053557.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
BASE COUNT         7815 a         4963 c         4157 g         7689 t
ORIGIN      
        1 taattgcctt catagatcga taaacagact tgttttacgc ttaatgtaat aattaatcta
       61 agtctgaaga aaaatcataa gacagcagaa actactgtct tatgatttag tttaagcatg
      121 ttacggtacc gctaccccac attgcaatta ttatttttta tcgtgaatgc caaatatctt
      181 cgttatactg ctcaatggta cggtcagatg agaagaatcc agcttttgcg atgttatgga
      241 ccacttttgt catccataaa tcttggtctt catagtctgc taacattttt tctttcactt
      301 caatgtactc ttcaaggtca atcaaagtca tgaaccagtc ttttgaaatc aattctttat
      361 aaagacgatc aagacgttct tcgttgccaa atgctagcaa ttctggactg ataataaagt
      421 tcactgctgc tttaatagca ggatggttat catagtaatc ttttgctaca taagaagcag
      481 tcgcataaag gttgatgatg gtgtcagaat ctttaccaaa ggtgtagata ttctccatgc
      541 ctgcaagctc agcgatttct acgttagcac cgtccattgt accaagtgtt aaagcaccgt
      601 taagcatgaa tttcatatta ccagttccag aagcttcttt ggatgctagt gaaatttgct
      661 cagaaatatc agttgctgga atcaagtgct ctgctactgt cacgttgtaa ttttcaacta
      721 gatgcacatt aaggtatggg cttacttcag ggtcattgtt aatcaattca gacaagcaaa
      781 ggatcaagtg aatgatgtct tgagcaatga tgtaagcagg cgctgcttta cctccaaaga
      841 taacagtgat tttacgtttt ggaaggttgc cttttttaat ttccaaatat ttgtgaatca
      901 cgtaaagagc attcatctgt tgacgtttgt actcgtggaa acgtttgatt tgggtatcaa
      961 taatagaatg ttcatcaagc tcaatgcctt tattgtcttt aaggtaacgt ttaagagcta
     1021 atttgttgtt gaatttgatt tcagccaatt tagcatgaac agctttgtca tctgcaaagg
     1081 ccatcaattt ttctaatttt gttgcgtcag tcaagtactc atcgccaata agttctttaa
     1141 tgtaatcagc caagtcttgg ttagcaaatt ctagccaacg acggaaagta atcccgttgg
     1201 ttttgttgtt gaatttttct gggtaaaggt catagaaagc ttttaattcg ctgtttttca
     1261 agatttctgt gtggagtgct gctaccccat tgacacttgt tgcaaaatga atatccatat
     1321 gggccatgtg cacacgacct gattcgtcaa taatttgaac agctggatca gacacttctg
     1381 aacgaacaag agcatccaat ttttcaatga tggttaccaa gtgtggcact acttcgttta
     1441 agtaagcagt tggccatttt tcaagggctt ctgcaagaat agtgtggtta gtgtaaccaa
     1501 ccatattttt cacaacagct accgcttcat caaagtcaaa gccatgtttt tcagtcaaga
     1561 gacgaattaa ttctgggatg accattgatg gatgcgtgtc attgatttgc acgtaagcgt
     1621 agtctgcaag gtcatgaagg tttgaaccac gttcgatagc ttcatcaatg attaattgcg
     1681 ctgcatttga caccataaag tactgttggt aaatacggag caattcccca tttttgtcag
     1741 aatcgtctgg gtagaggaac aaggtcaagt ttttagcaat ttgcgtttta tcaaatgaaa
     1801 taccgtcttt gattaacccg taatcaacgc cctcgatatc aaacaagtta aggtagtttt
     1861 tagtgtcgcg tttgtaaccc aaaacatcaa tacgatcaag acgagatttc aaggtgaagt
     1921 tcttaaaagg cacatcgtaa gaaatgtctg ttggaaccaa ccatgagtca tcttcaatcc
     1981 agaagtttgg ctcagcttct tgctcattgt gtttgaagac ttgcttaaac aacccacaat
     2041 gatagtttaa accaacccct tcaccattaa tcccaagaga tgaaatagag tcaatgaaac
     2101 atgaagcaag gcgtcctaaa ccaccattac ctagtgatgg ttctaattca acatcttcga
     2161 cttctgcgat agatttgcca gcagctgcca attcttcttt gatatcttta taaattccta
     2221 ggttaatcag gttgtttgat agtaatttac caatcaaaaa ttccgctgag atatagtaaa
     2281 ctttgcgttt ggcagtattt ttagctttgt ggctagcttc ttctttgaca aagtttaata
     2341 atgatagata aatctcttca ttgctagcct gcgtaagtga ttttcctagt ttagtttcaa
     2401 catattctgt aaagcgtgtc atgtcttcct cttttcaata atgtaacatt taaatattat
     2461 cttgcgcgac cataaagatc tgttaaataa ataaggtaat ctttgtgatc ttggttcaat
     2521 tcaccgtcaa gcatacgcca ttgccaatta cctccaattg tatttggcat attcatacga
     2581 ctcttaccat ctttatctaa taaatcttgg atgcaaagaa tggctgtatc acaaacagaa
     2641 gcaaagattg ttcttagcat ggcttttgta atactttcat ctgcatgttt gtgaagatag
     2701 ttatttacaa agtgtacttg ttcttcacta agattgtcat accatccgtt aaccacctcg
     2761 ttatcatgag tccctgtgta agcgacacaa ttacggtcat agtaatgtgg taaatctata
     2821 ctttgactcg ttatatcaaa taaaccaaat tctaatatct tcatgccagg aaagcctgtt
     2881 gatgctaata gctgctctgc tttttcatca atataaccaa ggttttctgc gatgataggg
     2941 agctctccta aggcctcacg aaccgcagaa aataatgcta tacctggggc tgaggcccaa
     3001 tggccatttc tagcagtttt atcaccagca ggaatttccc aaaaatctga gaagccttta
     3061 aaatgatcga ttcttagctg atcatatagt ttgaaacttt cttgaatacg ataaatccac
     3121 catgcaaaat tagacttttc atgagcagac caattgtagg ttggatttcc ccacagctga
     3181 ccatcttcac taaagccatc tgctggtaca cctgcaataa acaatggctt tttatcacta
     3241 tctactttaa atagctcagg catcgtccaa acttctacac tgtccgcaga aacataaata
     3301 ggcatatcac caataatttc tatcccttta tggttagcgt aagttttcaa ggctgaccat
     3361 tgttggtaaa agaagtattg acagacttta tgataggtaa tcttttttgc aagcaactca
     3421 cggtaattat taagtgagtc ttcttggcgt ttaatgacag tttcgtcgtc ccaatcttgt
     3481 aaggctttat tgttaaaata ttcttttaaa gccataaatt cagcaaaatc agttaaccag
     3541 ctagaagctg tttcaaaagc ttctaattta cacacatttt cttgttcagc aacaaaagct
     3601 ctcactgctt tttctaaaag tggacgccta acttgaaaaa gctgagcata gtctactgct
     3661 tcaggatttg tgccgaatgt aatatcacac aaatctgctg cttctaaaag ttcatcatct
     3721 actagcaatt caaaatcaat gaaatgtgtg ttcccagcaa tagctgaaaa tgactgataa
     3781 ggagaatctc caaaactcgt cgttgttaaa ggcagaattt gccaataggt ttgtttcgtc
     3841 tctgctagaa aatcaacaaa ttcaaaagct gattttccaa aagtgcctat cccaaatttc
     3901 ccaggcaggg aactaatatg cattaagata ccgcttgcac gtttgttcat gatttttctc
     3961 cttgtgaaat ctattcatga tgagattata acgcaagcgc ttgcgtaagt caaccagttt
     4021 cctaaaaaaa gtaacattcc ttaaaaatgc tacttttttt tgctcttaat gactaatatc
     4081 acggacgctt tctctttgtt ttaaactaaa aggaacaaaa atagtctgac taagattctg
     4141 ttcattggaa ttgataatat caagtaattg cttaaaagac atttttccaa gattttcaac
     4201 atttatatca aatgtcgtta aataagggtg aattaattta gcgtaattag aattattaaa
     4261 agtgataatt gacatatcat ctggcacttt tatatcataa aaagataata actgtaccat
     4321 acgaatagcc agaacatcac caacaacaac caaggcagtt gctttaaagg aagatatagt
     4381 ttccatcaat atttctacgc taacaggatc cttacgatca aataacagca ttggcttcgt
     4441 ttttaaagat cgcttaaaac aacccttcaa atagccaaga taacgctcag aagttacttc
     4501 tgatagtaaa tcatctgtta taaataatat gttgtgatgg cctttttgat aaaggtgttc
     4561 tactgctgtt ttagccatta gctgattatc attatcaata taagtggttt tattagtgtc
     4621 accttgtgga gcacctacaa tgacaaatgg taagttattt gtcatcaaat attttttgac
     4681 aggatcatct tgatcagaat aaagaataat aaaaccatca actcgttttt gaagatgcat
     4741 cagtttcact tgctctatca ggtcatcaag agatatacct gtagcaatcg acacagtaaa
     4801 atgagattct ttagcttcgt tagtaatagt cgacaaaatt tccataaaga aaggttcact
     4861 taatctatcg ctagttgtaa taggaggaaa aacaagtcct atattgtgtg tcaaaccact
     4921 cgctagaatc tgtgctgcga catttggaac atatcccaaa tctgccatcg cttttctaac
     4981 cttctctttt gttttcatag aaatagatcg attatctttt aataccctac tcaccgtcga
     5041 agggttaaca cctgcctttt gagcgacatc ttttattgtt accatattaa cctcgttact
     5101 atatttacca aagataaacc ttatcatggg tttgtcatgt atttcgtttc cattatacaa
     5161 ttatctttca aaaaatcaac ttcaatcaag attcccttgt cattttaact caaattctct
     5221 aaactatttt taaaaaaaac gacctttttt taaaaaaagg cttgactttt tctgcaagcg
     5281 gttgcataat attaagtgta agaaatatac cttaggagga aatagctatg aaatcatggc
     5341 aaaaagttat cgtcggcgga gcaagtttga cacttgcaag taccttgtta gtgggatgtg
     5401 gatcaggttc aaaagataaa aaggaagctg gcgctgactc aaagactatt aaactttggg
     5461 taccgactgg ctctaaaaaa tcatatgcag ataccattgc aaaatttgaa aaagattctg
     5521 gttacaccgt taaagtggtt gaatcagaag atccaaaagc acaagaaaaa atcaaaaaag
     5581 atgcctcaac tgctgccgat gtcttttcac ttcctcatga tcaacttggt caacttgtag
     5641 aatctggtac tattcaagaa gttccagaaa agtacaataa agaaattgct gctacttcta
     5701 ctgatcaggc gctcgtcggt gcacagtaca aagggaaaac atatgctttc ccatttggta
     5761 ttgaatcaca aattcttttc tacaataaat caaaattagc tgctgaagac gttacttcat
     5821 atgatacaat tactacaaaa gcaacttttg gtggtacctt taaacaagct aacacttacg
     5881 ctactggtcc attattcatg tcagttggta acactttatt tggggaaaac ggtgaagatg
     5941 taaaaggtac taactggggc aatgaaaaag gcgctgctgt tcttaaatgg atcgcagacc
     6001 aagcttcaaa taaaggtttt gttagcttag atgctaacaa cgttatgtct aaatttggtg
     6061 acggttcagt agcttctttt gaatcaggac cgtgggacta tgaagctgct caaaaagcta
     6121 tcggtaaaga aaaccttggt gttgctattt atccaaaagt aactattgga ggcgaaacgg
     6181 ttcaacaaaa agcattcttg ggtgtaaaac tttacgcagt caaccaagca ccagctaaag
     6241 gtgatacaaa acgtatcgca gctagctaca aattggcatc ctacttgact aatgctgaaa
     6301 gccaagaaaa ccaattcaag actcgtaaca ttgtcccagc caacaaagaa gttcaatctt
     6361 cagaagctgt tcaatcaaac gaacttgcta aaaccgttat cactatgggt tcttcttcag
     6421 actacactgt cgtaatgcca aaacttagcc aaatgggcac attctggact gaaagtgctg
     6481 ctattcttag tgatgccttc aacggtaaaa tcaaagaaag cgactacctt actaagttgc
     6541 aacaattcga caaagatatc gctgcaacaa aataatatga tctcatgtca tcactgctat
     6601 actaaaacaa gcacaaggta agtacttcta aaaagttctt tccacttacc ttatgaagag
     6661 tggaactagg ctccatcaca ttttattcaa gcttagtctc actcttactt gtttttgttt
     6721 tactagtagc ttagtgctac ttaaattttt aactctttaa aagtttacgt aacacttagc
     6781 tatttcatcc taacaagaga ttgaatctga actaccactc tagtatccta aaataaagga
     6841 gaatctatat gactcagtca aacttgacac caaatatatc tgtaatagaa gctttaaaaa
     6901 gaggcagttg ggatattaaa ctttcgagta ttatcatggg atttgccaac tttgctaaca
     6961 aacagtttat caaaggaatc ttatttttaa taagtgaact tatctttcta gtagcttttg
     7021 tctcccaaat catccctgct atccgtggcc ttgtcactct tggtactcaa actcagggaa
     7081 tgactacaaa aactattgat gggattaaca tccaagttgc tgttgatggc gataactcta
     7141 tgctaatgct tatttttggt ttagcatcac tcattttctg cctagtcttt gcttacattt
     7201 actggtgtaa tctcaaaagt gctcgtaacc tttatctttt caaacaaaaa ggtcagaaga
     7261 taccaaactt caaagaagat cttgccacac ttacaaatgg tcgctttcat atgactttaa
     7321 tggctatccc actgattggt gtgcttttat tcaccattct tcctttgatt tacatgatct
     7381 gtttggcctt taccaatttt gatcataatc acttgcctcc aaaatcttta tttgattggg
     7441 tgggacttgc taactttgga aatgttttaa gcggccgtat ggcaggaacc ttttttccta
     7501 tcttctcatg gactttgatt tgggctgttt ttgccacagt aactaatttc ttctttggta
     7561 ttattcttgc tttgttaatc aatgccaaag gattaaagtg gaaaaaaatg tggcgaacca
     7621 tctttgttat caccattgca gttccacaat tcatctcatt attgattatg cggaacttac
     7681 tcaatgacga aggcccacta aatgctcttc tcaataaaat cggcttgatt aatggctcac
     7741 tgccattttt atctgatcct ctttgggcaa aattctcaat catttttgtc aacatgtgga
     7801 tcggtattcc atttaccatg ttgattgcga ctggtattat catgaacctt ccaagtgaac
     7861 aaattgaggc tgctgaaatt gatggcgcta gcaaattcca agtcttcaag tctatcacat
     7921 tccctcaaat tctcttgatc atgacaccaa acttgattca acaatttatc ggaaatatca
     7981 ataactttaa cgtcatttac ctccttactg gtggtggtcc aacaaattca gaatactatc
     8041 aggcaggaac aacagacttg ctggtcactt ggctctataa attaaccgtc acagctgctg
     8101 actacaattt agcttctgtt atcggtatct taatctttac agtttcagct atctttagct
     8161 tacttgctta tacaaggaca gcatcctaca aggaaggagc ggctaaataa tgaaaaacaa
     8221 acgtcgattt caacttggac ttgtttatgc tactttaatc atcctctcaa tcatttggct
     8281 cttcccaatc gcttgggtta ttcttactag cttccgtagc gaaggaactg cttacgtcaa
     8341 ttattttatt cctaagactt ttacattaaa tcactacatt aatcttttta ctaatgaaac
     8401 ctttcctttt ggaaaatggt ttatgaatac tcttattgta gccactttta catgtattat
     8461 ttcaaccttc ataactgttg ccatagccta ctctcttagc cgaattaagt ttaagtttcg
     8521 caatggcttt ttaaaactag cccttatttt aaatatgttc cctggtttca tgagcatgat
     8581 tgccatctac tatatcttaa aggccttagg tttgacgcaa accctaacag cacttgtcct
     8641 tgtttattcc tcaggtgcag cccttggttt ttacattgca aaaggatttt ttgataccat
     8701 tccttattca cttgatgaat cagctatgat tgatggcgct actcgtatgg atattttctt
     8761 taaaataacc cttcctttag caaaaccaat cattgtctat actgcccttc ttgcttttat
     8821 ggggccttgg attgacttta tctttgcaca agttatctta ggtgatgcta caagtaaata
     8881 taccgttgct attggactat tttcaatgct tcagccagat accattaaca actggtttat
     8941 ggccttcact gctggttctg tcttaattgc cgtcccaatc actctcctct tcatgtttat
     9001 gcaaaaatac tatgttgaag gcatcacagg tggttctgtt aaataagtta caacatacca
     9061 aaccttctaa gggcaagccc tttaggaggt ttttgataaa taaggccgta gataatcata
     9121 ttagtcctca catttatctt cagatcagcc aaatgtatta atgattcctt gacttttacc
     9181 atgaattcgg atataacaaa atgatgacat ctaaaattac cattaaagat attgcacgag
     9241 aagccggggt ttctgtggcg accgtatctt acgtgttaaa ccagcgcaat gatcaaaaaa
     9301 tcagcgaaga aacccgcaat aaagtgctac atattagtaa ccttcttaac tatacaccta
     9361 atcaggcagc cagggcatta gtcacacaac aatcaaacag tgttgtcctg tattacaaat
     9421 atgcagatag cattttagct agggctgaac aactgcatac cattagcttt ctatcccgcc
     9481 tattgcatga gcaggactat cagctggttt gcctaaatga agatagcatt gaaaaatttg
     9541 actgggcaga ccttattctg accttggacg ttgataatga taccttttac aaaattggaa
     9601 agcttaattt caaaccctta attgccattg atagctttgt taatgatccc ctcttctttc
     9661 aaattaatac agattatgct gctctcaaag atcaggctaa tcagtttttt aaggatgaac
     9721 cttataccct gctttccttg cctatcacta atcgtgagcg atatgagcat gtttctgcct
     9781 tctttccaag tttgcacatt gtaaacgacc taagagagct aacctacttt gaaaaggaaa
     9841 atcttttact cattgatgag agtttggatc aattctttgt gaactcttcg caaaaactct
     9901 actgcccacg tttttcccca aaaaaagggc aagttatctt agaggccatc gaatgggcca
     9961 aaaaacgcca gcctgataaa aaacataacc ttctggtgta acgcctgaga attaacctat
    10021 cttgactaat tccttgtaac tcaaaacctt gcctctttag ataaagaagc aaggtttttt
    10081 gatgtctaat ctaataacag ggcctgactt gtctcatcaa tctctaaact gtgttttgta
    10141 gaacacccag gtcagcatta ataaggtacc aaatacttgg caattcataa tcagtactgg
    10201 atcctgaata aagaaactaa gagcaatcgc cagtagactc ggccaagcca aacaattaac
    10261 catcaatcca agtccttcag agaagtttcg aatcataaat agccgtgatc gtttagtcag
    10321 agtcaaaaag aaagcgccta gaccaatcac aataagggta cccacacaca ccatgagaac
    10381 aaacgtcagc aaaagaaaac caagtacact ggctttatta ctgtcatacc attgctgatt
    10441 gacaaagtcc ttcactgctt taactgttgt caggtcagcg agtgactgct gctggcctct
    10501 aacgtgagca cggagttcct tgccatcagg ggtaacaaaa cgccattctt tttttgtcac
    10561 aataatttgt ctggttgatt ctgatgccaa ttgctctaaa tcgacctttg tcggtaaaac
    10621 agccaaaacc aattcaccat ctcgtcgaat cagagattga ccctgaaacg tatctttctc
    10681 aatctttcct tgggtcaatg cttgataggt tttgtctgtg ataggcgaca aactcttagt
    10741 tacaatccgt tccaagggat acgttgtcat gttagcatag tgtaacgtaa ctggaatcat
    10801 tattaaggcg ttcaaaaaaa caataataag aagattttgc caccaagtaa actgagctcg
    10861 gctggcaaac attgccctag cagaaaggca atgtgaaatg taagaaatag gaaattgttt
    10921 tttatctggc attaaacatt actccttgtc aggttaccct ttggtaccac cacttgttaa
    10981 accggaaacg aaatttttct gtaggaagaa aaagagaact gaaataggca ctgcaatcag
    11041 aatagctccc gcagcaaata aggttacctt gggatttcta gcatcattcg taataaacga
    11101 ttgaagacca actgctaccg tataattttc ttgcgccctt aaaaggaatt tagccaacat
    11161 gaagtctccg aaaggaccca taaaagccca taaggattgt actgcaatca ttggtcgcac
    11221 aagaggaagg acaatttggt agaaggtcct aaagtgtcca gaaccatcta acttagcaga
    11281 ttcgtccaag tcataaggta ccgtgtcaaa ataacccttc atcaaccagg cattcatagg
    11341 aataccacca ccgacgtaaa tcaaaatcaa gaaccagtat tggtttaagg cattaaagag
    11401 ccacgccata acaaagtaag ccgttaaagc cgccatggta ggaaccatct gtacgactag
    11461 gaaaaagatt aaactttttt tgcgtccaaa gaaattgtaa cggctatacg cataacctgt
    11521 caaagtgatg actgttactt gtatgagcat ggtgaagaat gccacgatca aggtattcca
    11581 ataccatctt aagtataagg tatcttgaaa gagtgtttta aagttagaca aggtccatgg
    11641 cccatcaaaa tgaaaactaa aggctgtggt atttcctggt ctaaaagctg aactgaccgt
    11701 cactagtatt gggaataaaa tcacgatcac taaggagatt agatagagat aagtcaataa
    11761 ttgggtgaag aaacgtttgc gtttcatgga tattgaaaca taggtctttc tcatgatctc
    11821 tcctccatat caaaagcttt aaatttctta aaggtaatca acgataccga aatcactatt
    11881 acagagatga ttaaggtcac tgccgacgcc atcgaaaact gaggcgaggt ttgtgtggtc
    11941 aacttgtaaa tccaagaaat cagaatatca gttgtcccag ctccgccccc cacagtacca
    12001 gggcccccat tattaaacag ataaataata gagaaattat tgaagttaaa ggtgtactga
    12061 gagataaagg ttggtgctgc aaccgcaaaa atcattggca tggtgatatg gcggaatttc
    12121 tgtaagactg tcgcaccatc aacggttgct gcttcgtata aatcagctgg aattgcctgt
    12181 aaaatacctg ataccaaaat atagatatag ggaaatccta gccaaccttg caccataata
    12241 acagccactt ttgtccagaa ggggtctgtc ttccaggaca caattccgaa gtcaacgaaa
    12301 ggaaggaatt tctcgatgaa aggaagaacc tgaacattca tggccccaat ggaatcatta
    12361 aagaaattac caaaactcat aatagagata aatgctggaa cagcccatgg taacaagaat
    12421 atcacaccaa agagacgttt tcctctgata aaggattgat tagcaataac agccgttgca
    12481 attccaataa caatttgaag acttgtcgct gctaatgtcc agatcagcgt ccatgacaaa
    12541 acagatgtaa atgctgtttt gaaggtgctt aattctaaga tattaagaaa attcttcaac
    12601 cctacccaat ccaataaacg atacggagga atatgcctaa aatcgtaatt ggtaaaagca
    12661 atcagcaagg tcactaaaac tggaaaaata atagcgaaag ccattgctaa ataagccgga
    12721 atgatgagca agtaaggaaa tcctttttca taaatcgctt caagggtctc tttagccgtc
    12781 accggaacct tcttgccttc attcatttga tgtgcaacta atttagcatc tctcatagca
    12841 accaaatgaa aaataccaaa taagactaga gtaattaatt gcatggcccc cttaattaac
    12901 ataaataagg agtgatcttg cattggaaca cttccaagac tgtaaaaacc tgttaaagca
    12961 ggaattccta gaactacaat ttctagtagt tctaggaaga aaacaactaa taagactccc
    13021 cctttaacga tttgtttatt gtatagttgt cccaaacctg ggataacaga tagccacatg
    13081 gctttattag gcttctgttg tctttggtta tctaccattt tttattcctc ttctcataaa
    13141 tgatttaagg ttatactcct tatcatacta acttcctttt aagctgacta atttattttt
    13201 ttatagtaat ggtttgtgct tcatgacctg tctttatact ataagtctca ggacttgtcc
    13261 ataaaacatt cccaatacta tcttttttaa caagtttgac tgctatttct ttattgattg
    13321 gtagatgagt atcaaagaac cagtttgggt acttggcaat ggtctgagtg ttattaaata
    13381 gaggaccaac agcattctta gcgtcatttg cccccatctc aaaaacatca cccatgagat
    13441 atagttgttc ccctggtact gtcttaaaat cattgatgag taaacgaaca ggaatttgtt
    13501 tatcagtcaa tacttcaaag gcttggtaac tattgctggt ttgcttatcg gcagttgtca
    13561 ctgaaatgtt ataataattt gctggaaccg tcggtacttt taaggtgata agggtatctg
    13621 accaagaaag gatctcagca gagatttctc caaaagtcac ttgaccttta gaattaccaa
    13681 aaccttgacc tgaaatagta atcttatttc cagcaatacc cactgaagca tcgacatctc
    13741 caagttgtgg tgtcttgtcc tctccttcat aagtccatac agcgacttgc cccgctccaa
    13801 gttcaaagct actaatagtg ccatctgctc caactattaa ttcttgaccg ccaagaagac
    13861 cttctaattt gtccttgtag ctattttggg gcaaggctgt tttagcatta gtaattgtat
    13921 aaccattcgt ttgatctcta ttaatagcca ctagtgcgac atgattacca aatttacgct
    13981 caaataccaa aacatgatca ctaatccaac gttgttcagt tgttccataa gctaaagctt
    14041 gattttgttt tcttaaagga gctagcttac taatcacttt ataggcttgt gactctttat
    14101 taaaacttgg catatcacca cgattattag gatctttatc acctgttgca tactgctctg
    14161 taccataata aatattaggc acacctctag atgttaaaag caaagcatag gcttgattaa
    14221 cagcagtttg attattagcc acttttgttg cgaagcgttc catatcatga ttatcaataa
    14281 aggtcacctg gtctgtcact tcattagtca cctgatctct attttcaaga accttgtaaa
    14341 aatctcgcat ggtaaacgtt gaaaaacctg tatacaactg tctaatagca ttggcaaatc
    14401 taaaatctaa aagccccatc ccactattgt tagcaaatgt cgtcatatca taatcatcgt
    14461 cggtatgtcc cgagaaccat tccccgaaaa caaagacatt atgtttttca tagatatgac
    14521 tcaaccaatt tttttgccaa ccttgtgaca tatgtttaac agcgtcaact cggataccat
    14581 caacacccag gtctaaccat ttatcaatag cttctttcat gtactggtca actttcggat
    14641 taatgttatt taaatcagct agtccgtaca ttgaatgata aatagaattt tcataagtac
    14701 taaaatcggt ccaagattca tgattaaaaa tcttgtcttt atcatctgaa aatttaccaa
    14761 ctaatttacc gtttttatat aaagcgccat cttctttgaa agttgtgcct tctttttcgg
    14821 ctgtagacgt atgattagga gcaaaatcaa taactacctt aatatggtgt tgatgagcta
    14881 ctttgactag ttgttgaaag tctgcttcag tgccaaaatg ctggtttgtt ttaaagaagt
    14941 ccttagccca atacccatga tatgcagcac ttccattaga aggatcaata ctgtcgatat
    15001 tttcaacagg agaagaaatc caaatggcag aaatccccat atctgtcagg taaccatcct
    15061 taatcttggc gatgattcct tgccaatcac ctccatggta ttttttaagg tcatttttat
    15121 caaaaacatc agtcttacca ttattagagg tattaccatc gttaaaacga tctgttacaa
    15181 tctgataaat cgtatctgtt gaaaaatctg ctttgttggt gacagaagca ttatcggcag
    15241 cagaaacagt tagtggaaat gaaattaagc caagtaaaac agcacttttc gttaataact
    15301 tataagtttt gatatgtaat tctctcatcg ctttttcctt ttcaaataac cttttagtta
    15361 ctaaacacaa tatatccatc ctggagtaat tgttttttgt ttttagttac cccattgctt
    15421 gtcaaaatct gtcctccttc cttaatagaa taagcactct caccattgtt aagaacaagt
    15481 gaaatgcttt gctcacctaa gctgcgtttc agaatgaggc agtcttcgtc ataatcaatg
    15541 ctaatagctc cttcttgaag agctggctgt tggcgaagag caataatcgc ttttactttg
    15601 ctaaagaaat ccttgtcccg ctcagcatca tcccaaggaa aaccgcgacg cgaatcaggg
    15661 tcgtaacccc cttccattgc cacttctgtc ccataataca agcaaggaat gcccataaag
    15721 ataaagagca atgctaaagc agctaacaat ttatctttgg aacccttaac ttgagtgaag
    15781 aaacgatgcg tatcatgaga atccaaaaga ttcaagttca tgcgattgac ttgccaagtg
    15841 tttcgcatca aaatgttgct taatttctca gccaattgtt ttgatgtcat ggtttcaaaa
    15901 gcaaagtaat ccaaacaggc tttggtgaaa gcataattca ttatcccatc atactgatcc
    15961 cctgccaaat aaggataggc atcatgccag ttctccccaa ttaaaatggc atctgctttt
    16021 tccgctttaa ccgcctgacg gaaacgtcgc caaaaatcat gagatacttc atcagaaaca
    16081 tctaggcgcc aaccatcgat acaaaattct ttaatccagt atcgcccaat ctcaatcaga
    16141 tagtcttgca cgtctctatt tgaggtattc catttgggca tatagttaca tccagcaaag
    16201 gtttcatagt ttactaggtc catggatggg tgttcatcat gagtcataaa ccaatcaaaa
    16261 aacttagact ctttaccgta tctcaagaca tcctgaaatt ccacggcatc actgctggca
    16321 tggttaaaga cagcgtctag aataatcttg attcccattt ggtgagctaa atcaatcaat
    16381 tcttgcaaat catatttagt tccaaattgt ggatcaatag cgtagtaatc actaatatca
    16441 tatttgtgat tactaatgga ttgaaaaatt ggcgttaaat agatgacagt aatccctaaa
    16501 tctttgaggt aatctaattt ttctgtaatt ccctttaaat ctccaccagc aaaactttta
    16561 ggagtcggtt tttctaacca acccatgttg acataactgt cacctttttc ccaatcccca
    16621 cggttaaagc gatcaacaaa gatttgataa aaaaccgcgt cttttgtcca aggaatgact
    16681 tgatgaacat caacagcatt gatataaggc atttggaaga aattataaaa cccatttgaa
    16741 aaatcgtaac tagtagttaa cccatcttca ctaaaataat aggtttgacc ttcttcttca
    16801 attttaaaaa tgtaggccaa cctcacatcg tctaatgtta aagtagtttc ataataagca
    16861 tgcgtatggt ctgtataggc aactgacatt tccaattctt cttggaattc atgataacca
    16921 tatttaggcc cgtggaccaa attaacagta atacctctat cttctttggc cacgcgtaat
    16981 cggatgacaa gttccttttg agatatggca aagcaatacc tcgaatcagg aatatggagc
    17041 attccggcaa cattcatttc tacctccatt aataaagtat tgacgattac ttctttttct
    17101 ttaaaacgaa aaaatagcag agcgactcat acttctatat ttttagtatc tgtttcatct
    17161 tcatcaaact aacagaaata gaagctgggc gtacttcttt atcccagcct cccttctttg
    17221 ccttattcag cgtatttttg ttcaatagct tccttaatag tttttgctgc ttcttttgca
    17281 gctttagatg cttcttcctt accagaagcc acgttaaaga acatatttgc acctggttcc
    17341 caaacttcag ccatttctgg aatatttggc attggttgtg cgctctcaaa ctgactaatc
    17401 acagctttcg ttaactcatt accctcttta gaagcatagt tacgtgctgt taagttagct
    17461 ggaatttctt gtgttttatc atagaaacgt ttttggtttt cagcattggt cacataatca
    17521 aggaattttt gagcagtcgt ttttccttta gaatagtttg aaataaccca agctttacca
    17581 cctgcgaacg gttggtattt tttaccattt gtcaaagtag gaatttccat taccccaaag
    17641 ttaacaccag catctttaaa ggagctagct gcccatggac catcaataat gacaccagct
    17701 tttttagaaa taaattgttc agtgataaaa tcaccagctt ttttagtgtc ttgcattcct
    17761 tgaggccaag tgccatacca ctgtttcgcg tagtttaacc cttcaacagt tccgtcgtta
    17821 cctaggccta aatcacttgg tttggttcct ttatcaccaa agatataacc gccataaccg
    17881 gcaattaaac cataaccata atagaagtct gtccatttcg ccaagaaacc tacagatttt
    17941 cctggttcag aggcaaaagc aaacttagaa tctttttgta agacttctaa ttcagtaaag
    18001 cttttaggtg cttgaggcac taaatcctta ttataataag ttaccaaagt ttcaattacg
    18061 tctggtgcac cataagtttt accatcaatg gttactaatt tcttaaccgt atcatcaaac
    18121 tctttgctgt ttcctaaagt aacctcagag atttgacctt cagttcctaa gccacctaca
    18181 cggtcaaaag gtgctaaaaa gacatctggt gaagctcctg ttggaccatc cgttgatagc
    18241 ttatcaagag tatccatcat accttctttt ttgactttaa cggtgacttt atgctctttt
    18301 tcaaactcac ccttaatact cttaatgtaa tcaacatatc cctcatcaac agagactaca
    18361 atagtctttc cgtctgtttc cttaacgcct ttaccaccac cacttacgca agcagttagg
    18421 ggtagcactg aagctaagga taaagttcca agcacagatg cttttttcca attccatgac
    18481 ataacatgtt cctcccgaaa tggttttttc ttaaacacaa atcaaatcat ctatctactc
    18541 tcatcatatt agcaaataaa agataacata aggcatttaa aattaataac agtaatagtt
    18601 tcgaaactta aacgtttaag ttaagtttat cgtaatcgct ttcatttgtc aataactttt
    18661 ttacttttct tttaagagca tatcagtagt ttttctgcta attgaaaaca aggcatttac
    18721 tgtcacacaa gtctgtcctt tcttttttct acaactttat ttcgtcagcg taaataaaac
    18781 aaaagctcta taatctcttg aatgggtaaa cccactgtag agattataga gctttttgaa
    18841 tatcaaaaaa gtcccataaa atttataatg aaaagcaacc aaactctcat tagaaagact
    18901 cttatggaac atatcaatca taccttacaa cacatcggaa ttaaagacaa aaatatcact
    18961 ctaaacaatg ttttgaagga tgaatctcct actgagctcg ttactactta ccagaaaggt
    19021 agataggaaa tcctgatgaa gagtgtgtcc aagggattat caattaggtc ttagattaca
    19081 aaatagtaat tcaggtaggc tctactgttt tcaacactag ttctgcaatt tgttttcgag
    19141 cttgcttagc ttctcttatt ggaaaaataa catacgcatg aatcattttt tctgcaataa
    19201 tcagctgatt agcaattcgt tgtcttgtta attgatcatg taaagacata atgtctgggt
    19261 aaaaaatttc ttttgtccca acaaaggtcg ttatttcagg caaatcctca caatcaccat
    19321 acaaaggact gacataagga agttgcatat taccttgacc acctgcccat agttcaccta
    19381 tatcacgaag acgacgagca tctaggtaag cttcttctgc ttcaaaatcc ttgtaggctt
    19441 gatttttaaa actaacatct aaccaaggag atataagaat taattgcttt ggctgtagtg
    19501 ctgttttagt atctcgtata tacttagcaa acgccaaagc catcccccca ccagaagaat
    19561 caccaatgac actaacttga ctcggtccat tagacaagca aaattgctgg taagcttcaa
    19621 ctaatttagg atagacatct tgataagtag catacggtac tttaggaaag ttaggaaaaa
    19681 caaccttggc attagtcagc tgtataagat gcttaaccgt cttaaaatga agtttttcgg
    19741 gtcgtcgtaa atagacactg ccataaagat aataaataac aggctgatga ctttgctttt
    19801 gatcattaat aataaaaact tgtatcccgt tcacatcgta ttcttgagtt gaaaaaccta
    19861 ctatctcttc aggattatct agatgataag ggatattacg attacgctgc gtctcaaccc
    19921 ccttataatt atcaactttt ttagataact tatactttct ataagcaaac attttctcaa
    19981 ccaaccaact tgaaaaggag cgcttttgac catattcaac tatcaaaata cctagtatca
    20041 ctccaaaaaa aatcaccaca gcaataatga ccacttatta tcctcgtttt ctaatattat
    20101 tttactattg caagtctttc ctatttgccc aaattttact ataaaaataa gggttcattt
    20161 tatagttggg cactggctgc ttcgtttcta gaaatggttg cactttctta tcaaaagcta
    20221 accagccatt ccaaccgaga tggatggtat cttgcataaa gtaggactca ccaccatctt
    20281 ttgagaagtc agcaatgcga tgaaatcctt gtgactttaa ctggaatttt attttacgaa
    20341 ctgccgcttg atacttatct tgatttaagc cggtataatc cgcccaagct ttattaacag
    20401 gagttataac aaagagtaca tctgtttttc gtttagcaaa ttctgataat aaaagctgaa
    20461 aatcattgta ttctggtgac gccaggtaac tataattaac ttggaaattc ttataaagat
    20521 tgtatttagg tgctattcgt ttacgataaa atgtattttt aatcccaaaa cggttgttgg
    20581 ttgttgctaa ttggcctctc ttagttgcta acgcattcaa ttgtttatac gaaaatactt
    20641 taggtaatcc cttaacgcga ggcaaaattc ttttttcata gttagtagat ttgcctaaaa
    20701 aactaaaaag ggactcttct ctcaatgcta cttgatgttg acatttcaaa atagctctgt
    20761 ctaaccgact aagagactta cccttactta cttttttcaa taagtttgat ttagacacac
    20821 cagggttaag ctcaagcaaa cgctttgctg caaactgtga ttctttatca gttctagctt
    20881 ttagtaaaaa ttcaatcact tgagtgttag acaagtacat ctgaaccgca ctaggattaa
    20941 tcccttgagc agtaaaccat tgaggagata ctacaaagat ggcttttttc ttttgcattt
    21001 cattggtaat ttgttgcata ccataataat gcgacaaaga tgctgatcct ctcttaccaa
    21061 ttaaaaatgg tctatagctc cgcttgtagc gctctgcaag caccgaaggg tgcatactat
    21121 ccattcgact ccattcgcta gaaccaaaaa aaggcacaaa acgacaagtc tcatctgata
    21181 aagcttgtct tttaatcaaa ccatttttaa aagaactatc tgtgatcgca acggcatttg
    21241 ctttttcctg agctatggaa tgatcaagtt gtgtaggaaa actaaaaata gtaatcacta
    21301 ctaaaacaaa ggcaataaga agaggaccta gaattaacca gagtctctta agcatgttgc
    21361 aattcctcta caccttgaac aatcttagtt actgtgttcc aatcatcacg accaaattct
    21421 gaaataggta ctttaatatt gaacgttgac tctaactcaa caatcaattc gactgtccca
    21481 agactatcca acacacctgc atcaaacaag tcttcgtcca tcatctctga aacatcttcc
    21541 ataaacaaac ggtcaaacaa ttcaattaca gtttcttcaa tagacatttt tatacttcct
    21601 tttattaatg tagtggtctg ttaaaccaaa ggtcatttaa aaaaccagag aataacagaa
    21661 gtgaaaacat gacaacgtgg aaagttacca cgatacataa gacatggaat gccctgcttt
    21721 gaaagagggg tgataagcct tttttcttac ggtgacggtt gatttctttt ttcttacgaa
    21781 tccaagcatc attaataata agtcctatac catggaaaag cccataagcg atataatacc
    21841 aggttaagcc atgccaaaat cccatgacta gcatattaac cagataggca acacctgaag
    21901 tgacatttcg gtttttaaag gttttatgct taatcaatag atgaaccaat cgcataaaca
    21961 cataatctct aaaccagaag gacaaactca tgtgccatct attccaaaaa tctttcaagc
    22021 ttgcagataa gaaaggcatg ttaaagtttt ctggtgttcg aatacccaat aggtaggaaa
    22081 taccaatcgc aaacatcgaa taaccagcaa agtcaaaaaa gagattcaag ccatacacgt
    22141 acataaccag aatagtttcc ttattaaagt agccaccaac catcaaagcc ttattttcaa
    22201 ggagaggaag taagatgcca cccaaacaat aggaaatgat atgcttgtat aggaaaccta
    22261 acatgagata catgactgcc ttattgagca ttgcaaaata atcatcacgt tcaggaagtt
    22321 tatgataatc ttcctgaaaa cgtctgaagc gatcaatggg gccacttgag aaagtgggga
    22381 agaaaatcat gaagcgaata aaatccggta aacgaacctc ttggagagtc ccgtcacgca
    22441 tctcaataat cattccaata cttttaaagg tcaaatatga aatccctaga aaactaaaga
    22501 gtgtttgaga agaaggacct gttaggggag caactttgac ccagataagg gggaataagg
    22561 ccatcgcaat agctaagtaa aacactcctg cactattagc tttctcacgg tatttctggt
    22621 aagcaaaaac actgatgatt tgccacaaaa gataaaagag aaaagcaact aattgttgat
    22681 aatgatctcc tccaaacata aagagaataa ataccaaact taccaaggtt tcataagtgc
    22741 ttaagcgctt ttgtttaaaa atcccaatga tgactggtaa gaaagccaaa ataagataga
    22801 caaagtaaat ggggttaccg taaggttcca tgtagggaat gtggctaaaa aacatcatca
    22861 tcggttattg acctcattaa tcaaagtttt aatatctatc ttaccatttg gagttaatgg
    22921 tagactgtct cgataaagaa acttagaagg catcatataa ctcatcatat gatccttaac
    22981 agaggctttg atagctttgg ttaactccaa ttccctatca aaacgctctt taaccccatc
    23041 tttgacaacg atataggcca agagattttg aaccttatgt tctttattgt accttggaac
    23101 agccacagcc gatgctacca ttggtgattg attcaactgt tgggaaacat cttctagttc
    23161 aatacgataa ccagcatatt taatctgaaa atccaaacgc ccaccataca gcaaaatatt
    23221 atcttctgtc agtgagccaa tgtcccctgt atgataagca ggctgtcctt taaaagtaaa
    23281 gaaagcttct gcggttttct caggattgtt gaggtaacct tttgacacag caggccctgt
    23341 aacaataatt tcaccctgct cccctgaagc taactcctta ccatcttcat caataatata
    23401 ggtcggagaa tctggtttgg ggtagccaat cggcaagcgg gtataattat ccaccatttc
    23461 tctggtaatt tcaatagcgg ataaggctac agtcgcttct gttggtccat aggcattgat
    23521 gatcttggca ctcgggaaac gttcaaagag ttttcgagcc gtagaaacgg ttaattcttc
    23581 gccatcaaaa taaaaatgcg ttaaagctgg catcttagcc tggcaaaaat catcgctaag
    23641 catggccata tcagcaaatg aaggagtcga tgtccaaatg ccaactggaa gttgcgcaat
    23701 cgttgtaaat aactgtttaa agtctgccac caattctttt ggaagtgcaa ataaggttcc
    23761 acctaaagcc aaggtaggtg cccagtacat gacagaaagg tcaaaggaat agggtggctg
    23821 cgccagcatt tgtggctgtt taggtacatc aaatgctgca tcttcgatca tccagttggt
    23881 aaagctcaaa agattgtcat gtgaaatttg cacccctttt ggttggcccg ttgttccaga
    23941 ggtgaaaata atgtaataat tatcatctcc tttaacagaa tgtgttcgct catagggcat
    24001 ttctgctaat tttgctgact caatctctga tagtgagaca agggaaatcc cttcaatagt
    24061 aagagggaat tcctcaatag caatgattaa actgggcttt gcaatctcaa taatcgctaa
    24121 aatacgttct ggtgctgaat gcacatctac tgggatatag gcatgaccag atttggttaa
    24181 agctacaaaa gtagctaaca tatcataagt ttgcgcccca aaaaccaaaa ctggagattt
    24241 tgccagtaaa gctaagctat ctataaatgc agcaatgcta tcagaatctc ttttgagttg
    24301 tccgtaagtg cggtgttccc ctaaacaatc ataaactggg aaatcagcct gtgtctgagc
    24361 aaactgctca atactgtcaa tcatatcctt aatcatcagt caatctccta aaattcatta
    24421 taaataaagt tactttgacc atgtcctaga taaccaaaga aatagaccag caacattaaa
    24481 atcagataaa ataaaattgt cttgccaata aaaacagcaa ttcctctcat tcttgatttg
    24541 ttttttatca tactttacct tcttgtatta gtgaaataat gtcctaaaaa attctactcg
    24601 aaaaaaccta acttgacaag ctaa
//
LOCUS       DATWVB010000023        23548 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.023, whole genome shotgun sequence.
ACCESSION   DATWVB010000023 DATWVB010000000
VERSION     DATWVB010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23548
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.023"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            162..1397
                     /gene="arcA"
                     /locus_tag="VCX65_001093"
     CDS             162..1397
                     /gene="arcA"
                     /locus_tag="VCX65_001093"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEP5053558.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            1497..1925
                     /locus_tag="VCX65_001094"
     CDS             1497..1925
                     /locus_tag="VCX65_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP5053559.1"
                     /translation="MTDKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIV
                     TLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQSYGPKCLEDG
                     EYCQSLAKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNN"
     gene            1965..2978
                     /gene="argF"
                     /locus_tag="VCX65_001095"
     CDS             1965..2978
                     /gene="argF"
                     /locus_tag="VCX65_001095"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEP5053560.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMNLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            3148..4641
                     /locus_tag="VCX65_001096"
     CDS             3148..4641
                     /locus_tag="VCX65_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEP5053561.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGFFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            4658..5989
                     /locus_tag="VCX65_001097"
     CDS             4658..5989
                     /locus_tag="VCX65_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEP5053562.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFHTYIDPEGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTDPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYKG
                     NKLEALQKELDKLGFEYVVKEGELTVYGLAQHTKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            6009..6959
                     /gene="arcC"
                     /locus_tag="VCX65_001098"
     CDS             6009..6959
                     /gene="arcC"
                     /locus_tag="VCX65_001098"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEP5053563.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALISTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKSLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYINFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            7272..8264
                     /locus_tag="VCX65_001099"
     CDS             7272..8264
                     /locus_tag="VCX65_001099"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEP5053564.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKKHIGEVQTSVWPQEVRDSYDNIL"
     gene            8387..8926
                     /gene="rsmD"
                     /locus_tag="VCX65_001100"
     CDS             8387..8926
                     /gene="rsmD"
                     /locus_tag="VCX65_001100"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEP5053565.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            8916..9407
                     /gene="coaD"
                     /locus_tag="VCX65_001101"
     CDS             8916..9407
                     /gene="coaD"
                     /locus_tag="VCX65_001101"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEP5053566.1"
                     /translation="MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            9394..10431
                     /locus_tag="VCX65_001102"
     CDS             9394..10431
                     /locus_tag="VCX65_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEP5053567.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDTDFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            10846..11823
                     /locus_tag="VCX65_001103"
     CDS             10846..11823
                     /locus_tag="VCX65_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP5053568.1"
                     /translation="MVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARHKIKAAIAKLH
                     YTPNVLAQSLKTKKNQLVGLLLPDISNPFFPRLARGAEEYLKEKGYRVMLGNISDSEA
                     LEEEYVHVLLQSNAAGIITTHDFTKRYPTLAIPVVVVDCVDQETQYGVFSDNRAGGLL
                     AAQTVWQAGAKEVLLIRGPLDNAENINERFEASFSYLQKQDVTMYVCDSQNFDFESIQ
                     LEASYNLKCYPTIDSIIAPSDIHAIAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYP
                     SLSTIHQSSYLMGRYAAELVYTIASQLTVKANRIKLPVHYVERETIRKR"
     gene            12247..12891
                     /locus_tag="VCX65_001104"
     CDS             12247..12891
                     /locus_tag="VCX65_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HEP5053569.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPK
                     SKSKRVSKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            12895..13974
                     /gene="rlmN"
                     /locus_tag="VCX65_001105"
     CDS             12895..13974
                     /gene="rlmN"
                     /locus_tag="VCX65_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEP5053570.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(14056..14682)
                     /locus_tag="VCX65_001106"
     CDS             complement(14056..14682)
                     /locus_tag="VCX65_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEP5053571.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQLQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            14910..15437
                     /locus_tag="VCX65_001107"
     CDS             14910..15437
                     /locus_tag="VCX65_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEP5053572.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLCQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            15579..15782
                     /locus_tag="VCX65_001108"
     CDS             15579..15782
                     /locus_tag="VCX65_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEP5053573.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            15787..16758
                     /locus_tag="VCX65_001109"
     CDS             15787..16758
                     /locus_tag="VCX65_001109"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEP5053574.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIIASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            16768..17157
                     /locus_tag="VCX65_001110"
     CDS             16768..17157
                     /locus_tag="VCX65_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEP5053575.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRAKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            17340..19181
                     /gene="typA"
                     /locus_tag="VCX65_001111"
     CDS             17340..19181
                     /gene="typA"
                     /locus_tag="VCX65_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEP5053576.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            19303..19554
                     /locus_tag="VCX65_001112"
     CDS             19303..19554
                     /locus_tag="VCX65_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEP5053577.1"
                     /translation="MFYLIMAVSIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
     gene            19910..21268
                     /locus_tag="VCX65_001113"
     CDS             19910..21268
                     /locus_tag="VCX65_001113"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEP5053578.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
                     DA"
     gene            21268..22350
                     /locus_tag="VCX65_001114"
     CDS             21268..22350
                     /locus_tag="VCX65_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEP5053579.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISSAIKEK"
     gene            22351..23499
                     /locus_tag="VCX65_001115"
     CDS             22351..23499
                     /locus_tag="VCX65_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEP5053580.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKPKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLT
                     SPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMYDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQAPPSPETVLEQAHG"
BASE COUNT         7510 a         4165 c         4917 g         6956 t
ORIGIN      
        1 taaaaataaa aataacgccc cgaaaatgta agcgattact caaaatagct gtgagaaata
       61 ccctattttt atctttttta aggagtacac taggaatata agcaagagtt aagaatcttg
      121 acggtgaatt cacaaaaacc aattagaaag aggtaattct tatgactgct caaacaccaa
      181 ttcatgttta ttctgaaatt ggaaaattaa aaaaagtgtt gctccacaga cccggtaaag
      241 aaattgaaaa tcttatgcca gactacttgg aacgcttgtt gtttgatgat attccattct
      301 tagaggatgc ccaaaaagaa catgatgctt ttgcccaagc tttgcgtgac gaaggtattg
      361 aagtcttgta ccttgagacc ttagctgcag aatctcttgt cactccagaa attcgcgaag
      421 ctttcatcga tgaataccta agtgaagcta atatccgtgg aagagctact aaaaaagcca
      481 ttcgtgaatt gttgatggct atcgaagaca atcaagaatt gattgaaaaa accatggcag
      541 gagttcaaaa atctgaactt ccagagatcc cagcatctga aaaaggcttg actgacttgg
      601 ttgaatccaa ttacccattt gcgatcgacc caatgccaaa cctttatttc acacgggacc
      661 cattcgcaac tatcggtaca ggtgtttctc ttaaccacat gttctcagaa acacgtaacc
      721 gtgaaaccct ttatggtaaa tacattttca ctcatcaccc aatttatggg ggtggcaaag
      781 tgcctatggt ttatgaccgt aatgaaacca ctcgcattga aggtggggac gaacttgttc
      841 tttcaaaaga tgtgcttgcg gttggtattt ctcaacgtac agatgctgct tctattgaaa
      901 aattgttggt taacatcttt aaacaaaacc ttggcttcaa gaaagtattg gcctttgaat
      961 ttgcaaataa ccgtaaattc atgcacttag acactgtctt taccatggtt gactatgaca
     1021 aatttaccat tcacccagaa attgaaggcg accttcgtgt ttactctgtc acttacgaca
     1081 atgaagaact tcatatcgtt gaagaaaaag gtgatttagc agaacttctt gctgctaacc
     1141 ttggtgttga aaaagttgac cttatccgtt gtggtggtga caacttagta gcagcaggtc
     1201 gtgaacaatg gaacgatggt tctaacaccc ttactatcgc accaggtgtg gttgtggttt
     1261 ataaccgtaa caccattacc aatgctattc ttgaatctaa aggcttgaaa ttgatcaaga
     1321 ttcacggaag tgaattggtt cgcggtcgtg gtggacctcg ttgtatgtca atgccatttg
     1381 aacgtgaaga tatttaataa gctatggtaa aggtggttat aggtcagaag cctttttaaa
     1441 gggcagctag tgtttatctt cgcttctgtg tctttgtcct tcaatgaaat tttgtcatga
     1501 cagataaatt tgatgccaat gacgaaacaa gaacggttta tgcagtcgtt tatgacaatg
     1561 accagcccgt ttcaacagga caatttttag ctgaaacgaa aatagaagca cgattgacac
     1621 gcattgtaac cttagcagat tattgtggtt gcggttatgg tgccaaagtc actgaagcgc
     1681 tagaaactta taccagacga gaaggctttt accaactaac cattcacagt gaactgacag
     1741 cacaaacctt ttatgaaaac ctaggttatc agtcctatgg tcccaagtgt ttagaagatg
     1801 gtgagtattg tcagtccctt gcaaaaacca ttcttaaatg ggagaagaat atggacatag
     1861 caatgctaat tgcgattgtt ggtggtctat taggctgcta tctctatctc acaaaaaata
     1921 attaatcaaa acagattaca gttaacactc gaaggagaca atagatgaca caagtatttc
     1981 aaggacgtag cttcctagca gaaaaagatt ttacacgcgc tgaattagaa taccttattg
     2041 atttttcagc acatttgaaa gatttgaaaa aacgtggtgt gcctcatcac tacttagaag
     2101 gtaaaaacat tgccctcttg tttgaaaaaa catcaactcg tacgcgtgca gcttttacaa
     2161 cagcagccat tgacctaggt gctcacccag aatacctcgg tgccaatgac atccaacttg
     2221 gtaaaaaaga atcaacagaa gacactgcta aagtattggg tcgtatgttt gatgggattg
     2281 aattccgtgg ctttagccaa cgcatggttg aagaattggc agaattctca ggtgtgccag
     2341 tttggaatgg tttgactgat gaatggcacc caacccaaat gcttgctgac tatttaacag
     2401 tgaaagaaaa ctttggcaaa cttgaaggcc ttacccttgt ttactgtggt gacgggcgta
     2461 ataacgttgc caattccctt cttgtgactg gtgctatcct tggtgttaat gttcatatct
     2521 tctcaccaaa agaacttttc ccagaagaag agattgtgac attggctgaa ggctatgcta
     2581 aagaaagtgg cgctcgtatc cttatcacag aagatgctga cgaagctgtt aaaggcgcag
     2641 acgtgcttta cacagatgtt tgggtatcaa tgggtgaaga agacaaattc aaagaacgtg
     2701 ttgaattgct tcaaccatat caagtcaaca tgaaccttgt tcaaaaagca ggaaatgaca
     2761 agcttatctt cttgcactgc ttgccagctt tccatgacac aaataccgtt tatggtaaag
     2821 acgttgctga aaaattcggc gtgaaagaaa tggaagtcac tgatgaagtc ttccgcagca
     2881 aatacgctcg tcattttgac caagctgaaa accgcatgca cactatcaaa gcggttatgg
     2941 cagcaaccct tggtaacctc tttattccaa aagtgtaata aggactggta ctccttaact
     3001 catttcacat atcaatgtga cccctttaat ttaacaattt aactacttaa aaacgtactt
     3061 taactacatg acaagtcgtt ctggttttcg cgtccttgac cggaactaga acggcttatt
     3121 tttatgaaaa ggtaagaggt aatcattatg acagaagaaa aaaaacgggg ttttagaatt
     3181 ccttcttctt acaccgttct ttttatcatt atagccatca tggcagtgtt aacttggttt
     3241 attccagctg gcgcctacga aaccgctaag ggcggtggtg ttatttcagg aacctacaaa
     3301 acagtagcat ccaatcctca aggatttttt gacatcttga tggctcccgt tcgaggcatg
     3361 ttaggtgttg aaggcactga tggtgctatt caagtgtctt tctttatctt aatggttggg
     3421 ggctttttag gagttgtcaa caaaacaggt gctcttgaca cagggattgc gtcagtggtt
     3481 cgtaaaaaca aaggtagaga aaaaatgctg attgctattt taatcccttt gtttgctcta
     3541 ggtggaacga cctatggtat gggggaagaa accatggcct tttacccact tttaattcct
     3601 gttatgattg cggttggttt tgacagtatt gttgctgtag ccattatttt gattggttct
     3661 caaattgggt gtctagcctc cactattaac ccatttgcaa ctggtgtagc agctgatgct
     3721 gctggtgtca gcattgcaga tggaatgatt tggcgtgtta tccaatgggt tattcttgtc
     3781 ggcatgtcta tttggtttgt ttacaattac gctagtaaga ttgaagaaga cccaagtaaa
     3841 tcattggttg cagacaagga agaagagcat aaggaactct tccagttgca aaattctgga
     3901 gaagacttaa acaagcgcca acgaaacgtt ttgaccattt ttactttgac ctttgtcatt
     3961 atgattctta gtttgattcc gtgggaagat tttggcatca aattctttac caatatcaat
     4021 acttggttaa ccacaatgcc tatcttaggg ggagttattg ggaaaaccat gggagcattt
     4081 ggtacttggt atttcccaga aatcaccatg ctctttatca tgatgggtgt cttagttgct
     4141 attgtttatc gtatgagtga agaagacttt tttagctctt ttttgactgg tgcaggtgaa
     4201 tttttaggtg ttgccatgat ctgtgctatt gcacgcggta ttcaagttat catgaatggt
     4261 ggtatgatta cagccactat cttacactta ggtgaaacaa gtctttctgg tttatcttct
     4321 caagtttttg tgatattagc ttatattttc tacctcccaa tgtccttctt gattccatca
     4381 acatcaggac ttgctggggc tacaatgggg attatggcac cgcttggaca attctcaaat
     4441 gtccctgctc accttgttat tacagccttc cagtcagctt ctggaatctt aaacatgatt
     4501 tctccaactt cagcaatcgt tatgggagca cttgcgcttg gtcgcgttga ccttggtact
     4561 tggtggaaat tcattggtaa atttattgta atggtgatgc ttgtaagcgt gctattactt
     4621 gtagttgcaa cattctttta acagatagga ggttcctatg gaatcctata tcacacctaa
     4681 acatcaagag gcctgtgtag ctgccattaa acagatcgtt tcttaccctt ctgtttgtca
     4741 tgaaggagaa aatggcacac cttttggaca ggccattcaa gatgttctcg aagcaacctt
     4801 agacttatgt caaggtcttg gttttcatac ttatattgat cctgaaggtt actatggcta
     4861 tgctgagtta ggtgaccaaa aagaggtctt ggctattctt tgccatttgg acgttgttcc
     4921 agaaggagat cgtcagttat ggaagacaga tccttttgac tgtgttgagg cagacggctg
     4981 tttatttggt cgaggcactc aagacgataa agggcctact atgatggcgc tatttgccac
     5041 caaagccttg atagatgcag gtgttacctt taataaacgc attcgtttta ttttcggaac
     5101 agatgaagaa actttgtggc ggtgtatgaa tcgctacaat gatgtagaag aacaggctac
     5161 ctttgggttt gctcctgatt caagtttccc tttaacctat gccgaaaaag gcctacttca
     5221 ggcaaaatta gtggggaaag gttctgataa actgtcactt gaaatcggac aagcctacaa
     5281 tgttgttcct gcaagagctt cttataaagg caataagctt gaggctttac aaaaagaact
     5341 agataagctt ggctttgagt acgtcgtcaa agagggagaa ttaacggttt atggtctcgc
     5401 ccaacatact aaagatgctc ccgatggcat caacgctatg attaggcttg ccaaggcttt
     5461 agtggtcctt gaacctaaca aaacccttga ttttcttgct aatgtcattg atgaagatgg
     5521 cagagcactt aatatttttg gcagaatcga agatgaacct tcaggcaaat taagctttaa
     5581 tgccgcaggg cttaccttaa ccaaagacaa agcagaaatt cgcctagata ttcggattcc
     5641 agttttggca gataaggaaa aattagtcca acaattaagc caaaaagcac aagaatacgg
     5701 cctaacctat gaagaatttg attatttggc cccattatat gtgccattag acagtgaatt
     5761 ggtaacaacc ttgttatctg tctatcggaa aaaaacaggt gatcaaagcc ctgcccaatc
     5821 atcaggaggg gcaacctttg ctagaacaat gaagaattgt gttgcctttg gtgccctttt
     5881 ccctgatgct gttcaaacgg aacaccaaga aaatgaacat attgttttag cggatgctta
     5941 ccgcgctatg gatatttatg cggaagctat ttaccgacta acgcgataac aagatatgag
     6001 gagtaattat gacgaaacaa aaaatcgtag tcgcacttgg aggaaatgct attctttcaa
     6061 cagatgcgtc agcaaaagca caacaagaag ccttgatttc cacatcaaaa tcattggtta
     6121 aattaattaa agaaggtcat gaagtcatcg tgacccacgg caatggccca caagttggta
     6181 atctcttatt acaacaagca gcggcagatt ctgaaaagaa tccggctatg cctttggaca
     6241 cttgtgttgc catgacagaa ggtagcatcg gtttttggtt agttaatgcc cttgataatg
     6301 aattgcaagc ccaaggtatt caaaaagaag tggcagctgt tgtcactcaa gtgatcgtgg
     6361 atgccaaaga cccagctttt gaaaacccaa caaaaccaat tggtccattt cttaccgaag
     6421 aagatgccaa aaaacaaatg gcggagtctg gtgcaagttt caaagaagat gcaggtcgtg
     6481 gctggcgtaa ggttgtgcca tcaccaaaac cagttggtat taaagaagcc aatgtcatca
     6541 gaagtctcgt tgattctggc gttgttgtgg ttagtgctgg tggtggcggt gtgcctgttg
     6601 tggaagatgc aactagcaag tccttgactg gtgtggaagc tgttattgac aaggactttg
     6661 ctagccaaac cctttcagaa ttggtggatg cagacctctt tatcgttttg acaggagttg
     6721 acaatgttta catcaacttc aacaaacctg accaagccaa attggaagaa gtgactgtct
     6781 ctcaaatgaa agaatacatc acacaagacc aatttgcacc aggtagtatg ttaccaaaag
     6841 tggaagctgc cattgctttt gttgaaaaca aaccaaatgc taaagccatt atcacatcgc
     6901 tagaaaatat tgacaatgta ctatcagcaa acgctggaac acaaattatc gcagggtaat
     6961 caagaggatt tttagttctg tttaaaagac tcatttaatg gtattttctg aagagtacga
     7021 ctgacataaa gagttgatac tgtttttaaa ggaaaagagt gtgccataat aaaaaacaat
     7081 agtagtatta gaaaaggcta attttattga gaattagcct tttcttttag ctttgatagg
     7141 tgtataataa ccatactatt ttttattttt caaaatatta gaataaacaa aagtggacaa
     7201 cgtataaaga gaactgctaa gtcgttgagt tcattagtcc caaaaagatt accaaaaatg
     7261 aaggaggagc tatgaagaaa agttttattc atcaacaaga ggagatttcc tttgttaaga
     7321 atacgttcac tcagtatttg attgctaagt tagatgttgt tgaagtgcaa ggacccattt
     7381 taagtcgggt cggggacggt atgcaagata atttgtccgg tactgaaaat ccagtatctg
     7441 tcaatgtctt gaaaattcct aatgcaacct ttgaagttgt gcattcatta gcaaaatgga
     7501 aacgtcacac cttagcccgt tttgggttta atgaaggtga aggccttgtt gttaatatga
     7561 aggctctccg acctgatgag gattcacttg accaaaccca ttctgtctat gttgaccaat
     7621 gggactggga aaaagtcatc cctgatggca aacgtaatct cgcttacctc aaagaaaccg
     7681 ttgaaaccat ttacaaggtc attcggttaa ctgaattagc tgtagaagct cgttatgata
     7741 ttgaggctgt tttacctaag aaaataacct tcattcatac cgaagaattg gtagctaaat
     7801 accctgattt gacgcccaaa gaacgtgaaa atgccattac taaagaattt ggagcagtct
     7861 ttttaattgg tattggcggg gttttacctg acggtaaacc acacgatggc cgcgctcctg
     7921 actatgatga ctggacaaca gaaactgaaa atggctatca tgggcttaat ggtgatattt
     7981 tggtttggaa tgaccaactt ggttcagcct ttgaattatc ctcaatgggg atccgtgtgg
     8041 atgaagaggc cctaaaacgt caggtggaaa tgactggtga ccaagaccgc ttagcctttg
     8101 attggcacaa atctttgttg aatggacttt tccctctaac gattggtgga ggaatcggtc
     8161 aatcacgtat ggtcatgttt ttgttgcgta aaaaacatat tggagaagtt cagacctctg
     8221 tttggcccca agaagttcgt gatagctacg ataatatttt ataagtaatc acatcatttt
     8281 gctaagtttt ccacttgtat aagagacttt aaataaatga tcagaaatat tgaaaaaaga
     8341 aatcattttt aaggtttaga gctagaaatt tgctataata aatattatga gagttgtatc
     8401 aggtgaattt ggtgggcgtc ctttaaagac gctcgatgga aagataacac gccctacttc
     8461 agacaaagtt agaggtgcga tttttaatat gataggacct tactttaatg gtggtcgtgt
     8521 tttagatttg tttgcaggtt caggtggatt agccattgag gctgtttctc gtgggatgtc
     8581 tgctgcagtt ttggttgaga agaatcgtaa agcgcaagct attattcaag acaatattat
     8641 aatgactaaa gctgagaatc ggtttacctt gttaaaaatg gaagctgagc gagctattga
     8701 ttgcttgact ggtcgatttg acttagtctt tttagaccct ccttatgcca aagaaacaat
     8761 tgtggcaact attgaagctt tagcagctaa aaacttattg agtgaacagg ttatggttgt
     8821 ctgtgagaca gataaaacag tcttgttgcc aaaagagatt gcaacgttag gtatttggaa
     8881 agaaaaaatt tatggaatta gtaaggtaac agtttatgtt aactaaaata ggactttata
     8941 cagggtcatt tgatcctgtt acaaacggtc atctcgatat tgttaaacgg gcaagtggcc
     9001 tatttgatca aatatatgtt gggatttttg ataatcctac caaaaaaagc tattttaaac
     9061 tagaagttcg taaagcaatg cttactcaag ctctggctga ttttacaaat gtaattgtag
     9121 taacttcgca cgaacgttta gctattgatg tagctaaaga attacgagta actcacttga
     9181 ttagaggctt gcgaaatgca actgactttg agtatgaaga aaatttggaa tattttaatc
     9241 accttttagc tccaaatatt gagaccgtct atttgatatc aagaaataaa tggcaggccc
     9301 ttagctctag tcgtgtgaga gagctaattc attttcagtc ttccttagaa ggtttggttc
     9361 ctcagtcagt tattgctcaa gtggagaaaa tgaatgaaaa gacttaaaaa aatcaaatgg
     9421 tggttagtgg gtctgctagc tttaatctct ttgttgctag cgttattttt tccgctacct
     9481 tattatattg aaatgcctgg aggcgcttac gatattcgga ctgtcttaca agtcaatggc
     9541 aaagaagaca aacgaaaagg agcttaccag tttgttgcag tgggcattag tcgtgccagc
     9601 ctcgcgcagc tattatatgc ttggctgaca ccgtttactg aaattagtac agcagaagat
     9661 acaacaggcg gatacagcga tactgatttc cttcgaatta atcaatttta catggaaaca
     9721 tcacaaaatg cagctattta tcaagcttta tccttagctg gaaaaccagt tacattagat
     9781 tataaaggcg tatatgtttt agacgtaaac aacgaatcta cttttaaagg aacgttacac
     9841 ttagcagata ctgtaacagg tgtaaatggt aaacagttta ctagttcagc agaacttatt
     9901 gactatgttt ctcacctaaa actaggggat gaagttacgg ttcagtttac gagtgataat
     9961 aagcctaaaa aaggagttgg ccgtattatc aaactgaaaa atgggaaaaa tgggattggc
    10021 attgccttga ctgatcatac aagtgtcaat tcagaagaca cagtgatctt tagtactaaa
    10081 ggagtaggag gacctagtgc tggtctaatg tttactcttg atatatatga tcaaataact
    10141 aaagaagatt tacgcaaggg ccgtacaatt gcaggtacag gaactattgg caaggatggc
    10201 gaagtaggag atattggtgg tgcaggtctt aaagtagttg cagcagctga agctggtgca
    10261 gatatatttt ttgttccgaa taatcctgtt gataaggaaa ttaaaaaagt taatccaaat
    10321 gctataagta attacgaaga agccaaacgg gcagccaaac gactaaagac caaaatgaag
    10381 attgttcctg ttacgactgt tcaagaggca ctggtttatc ttcgcaaata aaataactat
    10441 gaatgtatta tattcaatta tattcacgct attaactcat aaaaaaacgg ttgaaccaga
    10501 tagacagatc cttgaccagt cttttgggtt caatcatttt ttacataaaa catatctaac
    10561 ttgacagcgt aaaaaagatg ttataaaagt ctagtggtaa aaaggcaata gagaattgag
    10621 taaactttag tcgattatct ggaaatagag catactaaaa acacctagtg aaaattgatt
    10681 tttttcacta gctcatccaa gaacttgcgc agataatcat gagtccattc catgactcta
    10741 ttattctgga aagccttgca atagacaagc taacgttata acaactaaat taaaaacttg
    10801 agattgaaaa atccccataa acttatttta caaggaggta aggctatggt aaccattaaa
    10861 caagttgctg aagaagcagg tgtttctaga tcaacagtct ccaggtatat ttctcaaaaa
    10921 ggatatgtat ctgatgatgc aaggcataaa atcaaagcag cgatagcaaa attacattac
    10981 actccaaatg tcttggcgca gtcattgaag acgaaaaaaa atcaactagt cggtttatta
    11041 ttaccagaca tttccaatcc tttttttccg aggttagcaa gaggagcaga agaatattta
    11101 aaagaaaagg ggtatcgggt tatgctagga aatatttcag acagcgaagc tcttgaagaa
    11161 gaatacgtcc atgtccttct tcaaagcaat gctgctggca ttattactac ccatgacttt
    11221 acaaagcggt atcctactct tgctattcca gttgtagtgg tagattgtgt tgaccaagag
    11281 acccagtacg gtgtcttttc agataatagg gcagggggct tattggcggc tcagactgtc
    11341 tggcaagcag gggcgaaaga agttctgtta ataagaggtc cgctggataa tgctgaaaac
    11401 attaatgagc ggtttgaagc tagtttttct taccttcaaa aacaagacgt gactatgtat
    11461 gtgtgtgata gtcagaattt tgattttgaa agtattcagc tagaagctag ttacaacctc
    11521 aagtgttacc caacaataga tagtattata gcaccttctg atatccatgc tattgcttat
    11581 attcatgaac tgcattctca aggtaaaaag attcctcaag atgttcaaat aataggttat
    11641 gatgacattt taatgagtca atttatttat ccttctttat cgactattca tcaatcctct
    11701 tatttgatgg gccgttatgc cgccgaatta gtttatacta ttgctagtca attaactgtg
    11761 aaagcaaatc ggattaaatt gcctgttcac tacgttgagc gagaaacaat aaggaaaaga
    11821 taagtaataa tattagtcca gattttagca ggtatgatga agatttattg ggatttacct
    11881 tctactttaa aagatgttat ctgtcattac tttcatcgct atcagtcaaa acgcattctt
    11941 atgcaactct taaccttaag cttaatgtct ttttgataac atagaggaat gttacacgat
    12001 gatgacgcaa taaagcctaa atatagtaat tgtcgtgatt ttatagctag tgagtaatga
    12061 gatagcaagt ctctcattta cttacaaaag tcaaaaaata gtgtataatg gttgagttac
    12121 agataacact gcaaaaaaga taacaagtgt ccataattat ctaagactat aaaggcgata
    12181 tagacagata taaaaaagat gacgaatcag ttatcactgg acaattaacc gatttagtta
    12241 caactaatgg atttttcaga aaggtgtcaa atgaaaaaag aaatttcgcc agaaatgtac
    12301 aactataata aatttccagg tcccaaattt attcattttg aagagcaagt taaggctgaa
    12361 ggcattgatt tgttactctt agaagatgtt aagaacgctt ttgatacgac tagctttggt
    12421 caacgttata cagaagttct cctaaagtat gactatattg ttggcgattg gggaaatgaa
    12481 cagcttcgtc ttaaagggtt ttataaggat agtgatgata tcaagaaaac gaatcgcatc
    12541 tcacgtttag aagattatat taaagaattt tgcaattttg gttgtgctta ttttgtttta
    12601 gaaaatcttc atccacaaga tattaaattt gaagaggagc gccaaccaag acgaaagaaa
    12661 tcacctaaat caaaatcaaa tcgtcgcaag ccaaactatt caaatcagca gcccgcaaca
    12721 cctaagagta aatcgaagcg ggtatcaaaa gaaaagcaac ctgaaaacca agcgtttacc
    12781 agtcaaaaac gtcgaagtaa tactaagcat aaagaaaagt caaaacgtaa tcagactagt
    12841 caacttaata ccaaaattag tcattttatc atcagaaaga aagataaata atccatgaaa
    12901 ccatcgattt atagcttaac acgcgatgaa ctgatcgcgt gggcagttga acgcggccaa
    12961 aaacagttta gagctactca aatttgggat tggctctata aaaaaagagt tcaatctttt
    13021 gaggagatga cgaatatttc taaagatttt gtttctattt taaatgatag tttctgtgtc
    13081 aatcctttaa aacagcgagt tgtacaagag tcagctgatg gtacagtaaa atatttattt
    13141 gaactgcccg atggtatgtt aattgaaaca gttttaatgc gtcaacatta tggtcattct
    13201 gtttgtgtga cgactcaagt tggctgtaac attggctgta ctttctgtgc tagtggattg
    13261 atcaaaaagc aacgtgatct aaacagtggg gaaattacag ctcaaatcat gttagtccaa
    13321 aaatattttg acgatagaaa gcaaggtgag cgggttagcc atgttgtcgt aatgggcatt
    13381 ggtgaacctt ttgataatta caaaaatgtc atgtgctttc ttcgcgtcat caacgatgat
    13441 aatggcttag caattggtgc ccgtcatatt acagtctcta cctcagggtt agctcacaag
    13501 attcgggatt ttgcaaacga gggagtacag gttaatttag cagtctcgtt gcatgcacca
    13561 aataatgatt tacgttcaag tattatgcga gtaaatcgct cttttccgct ggaaaagctc
    13621 ttttcagcta tagaatacta tattgaaaaa acgaatcgtc gtgtcacttt tgaatacatt
    13681 atgctaaatg aagttaacga tagcattaag caagctcaag aattagcaga cttaactaaa
    13741 actattcgta agttatctta tgttaacttg attccgtata atcctgtttc agaacatgat
    13801 cagtatagta gaagtcctaa agagcgagtt ctagcgtttt atgatgtgct aaagaaaaat
    13861 ggagttaact gtgtggtgcg tcaagagcac ggaacagata ttgatgcagc ctgtggccag
    13921 ttacgttcta aaacgatgaa aaaagatcgc gaaaaggtta cagcgacaaa ataaagccca
    13981 aaaaatatct ttgattgaca atgcttgatg acaaaatatt cctagtcact aaaatgacta
    14041 ggttttttat ctggcctaaa aatgctctag aagcacaatc caaaataatc caaaactaag
    14101 ataaggaata aaaggtatgc gcttgatgcc taatagtaag caagcagtaa tacctgctaa
    14161 actagcaagt tgaattagcc aaatcaacga cgttagatcc aatactaaag ctaagctagc
    14221 aaggtagaaa aaatcgcctg ctccaattga aaaaggtctt aaatgagcta ataaacctag
    14281 tagcagtaat atcaatgata aataattgat cgaataaaac aggagtagac ttacaaagct
    14341 aaaaagccac aagataaaag ggtattcttg agaacgccaa tcaaataaac taaataataa
    14401 agaaaagagt aacaagtaac agtaactagc actaacccaa tgtaccatac tagcccataa
    14461 gataattatt agacttatct ctaagctaaa gaagattttt tggctagtta taaaatggtt
    14521 ttggagctgc cgaaaaacgc gtttggcaaa agttagttgg tcacaaacaa tgacagtctg
    14581 tttacttagc tgttcttgac cattatcagg aaaataaagt agtaaacagt aaaaaagatg
    14641 ggtcaataag atgcccgaac atatactaaa aaaagctatc atacttattt attcgaaaag
    14701 aaatcaaata cttgcaatct ttccttaatc attgtagaat atagatataa aacgataatg
    14761 attctaatta agtgtctaat catccaatta ggattattcc gttattgtcg aataggatta
    14821 ggtccttaac cctttcttat gtttatcacg ttagggttag ttccccctcc attcttgccc
    14881 tttaagctga aaagtaagga gatgttatta tgacaaacac actcgttgaa aatatttatg
    14941 cttcagtaac tcacaatatt tctaaaaaag aagcatcaaa aaatgaaaaa actaaagctg
    15001 ttttaaacca agctgtcgct gacttatctg tggctgcatc tattgtgcac caagtacact
    15061 ggtatatgcg tggtccaggt ttcttgtacc ttcacccaaa aatggatgaa ttacttgata
    15121 gcttgaatgc taatttagat gaaatgagcg agcgtttgat cactattggc ggagcgcctt
    15181 attctaccct agctgagttt tctaaacact ctaaattgga cgaagcaaaa ggtacttacg
    15241 ataaaacagt tgctcagcat ttagcaagat tggtcgaagt ttacctttac ctcagcagcc
    15301 tttgccaagt tggtttggat attaccgatg aagaaggcga tgctggaaca aacgatttgt
    15361 ttacagcagc taagacagag gctgaaaaaa ccatttggat gctccaagca gagcgtggac
    15421 aaggcccagc actctaatgg attatgcctt aggataaaag aagtcaatga taaaattggc
    15481 ttctttttta tggaatcatc gattcatttt cagaaacata gaaagcgatt ccatacttgt
    15541 cttgaaattt gccgtagaat ttgctaaaat ctacttatat gaaaacacta tatgatgtgc
    15601 aacaattgct aaaaaacttt ggcatttttg tttaccttgg caaacgtctc tatgatattg
    15661 aaatgatgaa gattgaactt cagcgtctct atgatagcgg cttattggat aagagggatt
    15721 acttaaatgc ggagttaatt ttgcgacgtg agcatagatt agaattggaa aaagaaggat
    15781 agacaaatga gtcaaaaatt actggggatt gatttaggtg gtaccaccat taaatttgga
    15841 attttaacag cagcaggaga agtccaagaa aaatgggcaa ttgagactaa tattttagaa
    15901 ggaggcaaac atattgtccc tgatatcatc gcttccatca aacatcgctt agacttgtat
    15961 ggtctaagca gtgctgattt tgtgggaatt ggtatgggat caccaggagc ggttgaccgt
    16021 gatactaata cagttactgg ggcattcaac cttaattgga aagaaaccca agaagtcggt
    16081 tccgttgttg aaaaagaatt gggcattcct tttgccattg acaatgatgc caatgtggct
    16141 gcccttggtg aacgttgggt aggtgctggt gaaaataacc cagatgtcgt cttcatgaca
    16201 cttggaacag gtgtcggtgg aggcattatt gctgatggta acttgattca tggtgttgca
    16261 ggagcaggtg gtgaaatcgg ccacatgatt gttgagccag aaaatggctt tgcttgtact
    16321 tgtggctcac acggctgttt ggaaacagta gcttcagcaa caggagttgt caaagtggca
    16381 cgtttattgg cagaagctta tgaaggggat tcagccatca aagcagctat tgacaatggt
    16441 gaaggtgtta ccagcaaaga tatttttatg gcggctgaag caggggattc ctttgctgat
    16501 tctgttgtgg aaaaggttgg ttactacctt ggccttgctt cagcaaatat ttccaatatc
    16561 ttgaatccag actcagtggt tatcggtggg ggtgtgtcgg cagcaggaga atttctacgc
    16621 tcacgtattg aaaaatactt tgtgaccttc actttcccac aagtgaggta ttcaactaaa
    16681 attaagattg cagagcttgg caatgatgct ggaattatcg gtgcagctag ccttgctcga
    16741 caatttatca caaaatagga gggggatatg tctccaatca cacttatctt atggttactt
    16801 cttgtcggca ttgttggtta ttatacatgg aactatttct cttttcgaaa aatggcaaag
    16861 caggttgata acgagacttt taaagacgtg atgcgtcaag gtcaattgat tgatttacga
    16921 gagccagcgg cttttagagc taagcatatt ttaggagctc gaaattttcc agcgcaacaa
    16981 tttgatgctg ctatcaaagg tcttcgcaag gacaaacctg ttcttattta cgaaaatatg
    17041 cgtccccagt accgtgtgcc tgcggtcaaa aaacttaaaa aagctggctt tgaagacgtt
    17101 tatgtcttaa aagacggtat tgattattgg gatggcaaag ttaaacaaac aacctagtta
    17161 agagtaacgt ggagttaagg ggaataaagg tagtcactgt ctcaaaaacc ttaaatcctt
    17221 tttttgctgt atccagactt gctgaaagtc tgaaaacatt tacaattgat taaaaccagt
    17281 tttttaaaac attttgtgtt atacttatct agttaaaata tatttactta gaggaacaaa
    17341 tgactaactt aagaaacgat atccgtaacg tagcgattat tgcccacgtt gaccacggaa
    17401 aaacaacact tgtagatgaa ttattaaaac aatcccatac tcttgatgag cgtaaagagc
    17461 ttcaagagcg tgccatggat tccaatgacc ttgaaaaaga acgtgggatt acaatccttg
    17521 cgaaaaatac ggcagtagcc tataacgatg ttcgtattaa catcatggat accccaggac
    17581 acgcggactt cggtggtgaa gttgaacgta tcatgaaaat ggttgacggg gttgttcttg
    17641 ttgtggatgc ctacgaagga acaatgcccc agacgcgttt cgtattgaaa aaagcacttg
    17701 agcaaaacct tatcccgatc gttgtggtga acaagattga caaaccttca gctcgtccag
    17761 cagaagttgt agatgaagtg cttgaattat tcatcgaact tggtgccgat gatgagcaat
    17821 tggaattccc agttgtttac gcatcagcta ttaatggaac atcatcatta tcagatgacc
    17881 ctgctgacca agagcatact atggcaccga tctttgatac gattattgat catattccag
    17941 cgccagttga taattcagat gagcctttgc aattccaagt gtcacttttg gactacaacg
    18001 atttcgtagg tcgtatcggt atcggtcgtg ttttccgtgg tactgttaaa gtgggtgacc
    18061 aagtaactct ttcaaaactt gatggtacca ctaaaaactt ccgtgttaca aaactgtttg
    18121 gtttcttcgg tttggaacgt cgtgaaattc aagaagctaa agcaggtgac ttgattgctg
    18181 tttcaggtat ggaagatatc tttgttggag aaaccattac accaactgac tgtgtggaag
    18241 ctctgccaat tcttcgtatt gatgagccaa cacttcagat gactttcttg gtcaataact
    18301 ctccttttgc aggtcgtgaa ggtaaatgga tcacgtcacg taaggttgaa gaacgtcttt
    18361 tagcagaatt gcaaacagac gtgtcacttc gtgttgaccc aacagattcg ccagataaat
    18421 ggacggtttc agggcgtgga gaattgcatt tatctatcct cattgaaacc atgcgccgtg
    18481 aaggctatga acttcaagta tcacgtccag aagttatcat caaagaaatt gatggtgtca
    18541 aatgtgaacc gtttgagcgt gttcaaattg atacaccaga agaatatcag ggtgcaatca
    18601 tccagtctct ttcagaacgt aaaggggata tgcttgatat gcagatggtt ggtaatggtc
    18661 aaacgcgttt gattttcttg attcctgcac gtggtttgat tggttattca acagagtttc
    18721 tttcaatgac acgtggatat ggtatcatga atcatacttt tgatcagtat ctaccggttg
    18781 ttcaaggaga aatcggtggc cgtcatcgtg gtgccttggt ttctattgaa aatgggaaag
    18841 caacgacata ttcaatcatg cgtattgaag aacgtggaac tatctttgtc aacccaggta
    18901 cagaagttta cgaagggatg attgttggtg aaaactcacg tgataacgac cttggtgtta
    18961 acattacaac agctaagcaa atgacaaatg tccgttcagc gactaaagat caaactgcag
    19021 ttatcaagac gcctcgtatc ctaacgcttg aagaatcatt agagttcttg aatgacgacg
    19081 aatacatgga agtaacgcca gaatctatcc gcttgcgtaa acaaatcttg aataaagctg
    19141 cgcgtgataa agctaataaa aagaaaaaat cagccgaata gcttttgaag ttaaactaac
    19201 taaataaaat agcaaaaaga tatttaagaa aagtcatttt ttaaaggtct ttttgcgttt
    19261 acaagttcct atggaatata aaccaaaata aaggaggacg gaatgtttta ccttattatg
    19321 gctgtctcga ttatatctta ttatctatac atggctccta aaagtgtccg taacaccctt
    19381 gggatgattg gtttagttgg cttggttgct ctgcttattg ttttagcggg cttgagtttt
    19441 atcaaaatca tgcaaacccc tcctgaattt tttattggga tgggaatggt ggcattgggc
    19501 tattttgctt taaaagatgt gcgtaaaatg accaaaaaac cgagagttaa ataaaaatac
    19561 ttaaagattg atgattttgg tttttatacg ataaaaggac tgatttgttt tagacaatat
    19621 cagtcctttt ttaatagttc attttttctg aaagaaagct tttagccgat tttcattgag
    19681 tgtgcaacta aaaaaagatg cttggtagtg acagttaaga cctctgacta gtattttatc
    19741 ttactttact taaaaaaacg taccaataat ctcacaaata tgggcatgat gtttgtatat
    19801 tggaaacgga ttctaattct aaactcaaga acggtatttt taaaatgttg aaaaagcatc
    19861 taaataaagg taaaatagaa atcaaataga atggatagtg tgagcttaga tgaaagtgat
    19921 aagtaatttt caaaataaaa aaatattaat attggggtta gccaaatcgg gcgaagcagc
    19981 agcaaaatta ttgaccaaac ttggtgcttt agtgactgtt aatgatagta aaccatttga
    20041 ccaaaatcca gcggcacaag ccttgttgga agaggggatt aaggtcattt gtggtagcca
    20101 cccagtagaa ttattagatg aggactttga gtacatggtt aaaaaccctg ggattcctta
    20161 tgataatcct atggttaaac gcgcccttgc aaaggaaatt cccatcttga ctgaagtaga
    20221 attggcttat ttcgtatctg aagcgcctat tatcgggatt acaggatcaa acgggaagac
    20281 aaccacaacg acaatgattg ccgatgtttt gaatgctggc gggcaatctg cactcttatc
    20341 tggaaacatt ggttatcctg cttcaaaagt tgttcaaaaa gcaattgctg gtgatacttt
    20401 ggtgatggaa ttgtcctctt ttcaattagt gggagtgaat gcttttcgcc ctcatattgc
    20461 tgtcatcact aatttaatgc cgactcacct ggactatcat ggcagttttg aggattatgt
    20521 tgctgctaaa tggatgattc aagctcagat gacagaatca gactacctta ttttaaatgc
    20581 taatcaagag atttcagcaa ctctagctaa gaccaccaaa gcaacagtga ttcctttttc
    20641 aactcaaaaa gtggttgatg gagcttatct gaaggatgga atactctatt ttaaagaaca
    20701 agcgattata gctgccactg acttaggtgt cccaggtagc cacaacattg aaaatgccct
    20761 agcaactatt gcagttgcca agttatctgg tattgctgat gatattattg cccagtgcct
    20821 ttcacatttt ggaggcgtta aacatcgttt gcaacgggtt ggtcaaatca aagatattac
    20881 cttctacaat gacagtaagt caaccaatat tttagccact caaaaggctt tatcaggttt
    20941 tgataacagt cgcttgattt tgattgctgg cggtctagat cgtggcaatg aatttgacga
    21001 tttggtgcca gaccttttag gacttaagca gatgattatt ttgggagaat ccgcagagcg
    21061 tatgaagcga gctgctaaca aagcagaggt ctcttatctt gaagctagaa atgtggcaga
    21121 agcaacagag cttgctttta agctggccca aacaggcgat actatcttgc ttagcccagc
    21181 caatgctagc tgggatatgt atcctaattt tgaggttcgc ggggatgaat ttttggcaac
    21241 ctttgattgt ttaagaggag atgcctaatg cctaagaaga ttttatttac aggtggtgga
    21301 actgtaggtc atgtcacctt gaacctcatt ctcataccaa aatttatcaa ggacggttgg
    21361 gaagtacatt atattggtga taaaaatggc attgaacata cagaaattga aaagtcaggc
    21421 cttgacgtga cctttcatgc tatcgcgaca ggcaagctta gacgctattt ttcatggcaa
    21481 aatctagctg atgtttttaa ggttgcactt ggcctcctac agtctctctt tattgttgcc
    21541 aagcttcgcc ctcaagccct tttttccaaa ggtggttttg tctcagtacc gccagttgtg
    21601 gctgctaaat tgcttggtaa accagtcttt attcatgaat cagatcggtc aatgggacta
    21661 gcaaacaaga ttgcctacaa atttgcaact accatgtata ccacttttga gcaggaagac
    21721 cagttgtcta aagttaaaca ccttggagcg gtgacaaagg ttttcaaaga tgccaaccaa
    21781 atgcctgaat caactcagtt agaggcggtg aaagagtatt ttagtagaga cctaaaaacc
    21841 ctcttgttta ttggtggttc ggcaggggcg catgtgttta atcagtttat tagtgatcat
    21901 ccagaattga agcaacgtta taatatcatc aatattacag gagaccctca ccttaatgaa
    21961 ttgagttctc atctgtatcg agtagattat gttaccgatc tctaccaacc tttgatggcg
    22021 atggctgacc ttgtagtgac aagagggggc tctaatacac tttttgagct actggcaatg
    22081 gctaagctac acctcatcgt tcctcttggt aaagaagcta gccgtggcga tcagttagaa
    22141 aatgccactt attttgagaa gaggggctac gctaaacaat tacaggaacc tgatttaact
    22201 ttgcataatt ttgatcaggc aatggctgat ttgtttgaac atcaggctga ttatgaggct
    22261 actatgttgg caactaagga gattcagtca ccggacttct tttatgacct tttgagagct
    22321 gatattagct ccgcgattaa ggagaagtaa atggcaaaag ataaagagaa acaaagtgat
    22381 gacaagctcg ttttgacaga gtggcaaaag cgtaacattg aatttttaaa gaaaaagaag
    22441 cagcaagctg aggaagaaaa aaaactcaaa gagaaattat tgagtgataa aaaagcgcag
    22501 cagcaagctc aaaatgcttc tgaagcagtt gagcttaaaa ctgatgagaa aactgatagt
    22561 caggaaattg agtcagaaac gacgtcaaaa cctaaaaaac ccaaaaaagt tagacaaccc
    22621 aaggaaaaaa gcgcgacaca aatcgctttt caaaaatcct tgcctgttct tttgggggcg
    22681 ctcttactta tggcggtgtc tatttttatg atcactcctt atagcaaaaa gaaagagttt
    22741 tctgtaagag gaaaccatca aacgaacctt gacgaattaa tcaaagctag caaagtcaaa
    22801 gcatctgact attggttaac gttgttaact tcgcctggtc agtatgaacg accgattctt
    22861 cgtactattc catgggtgaa atctgtacat ctctcttacc aatttcctaa tcactttcta
    22921 tttaacgtta ttgaatttga aatcatcgct tatgcacaag tcgaaaacgg ttttcagcct
    22981 attttggaga atggaaaacg tgtggacaag gtcagggcat cagaactacc gaaatctttc
    23041 ttgattctta atttaaaaga tgagaaagcg atccaacagt tagttaagca attaacgaca
    23101 ttacctaaaa aattagtcaa gaatatcaag tcagtgtctc ttgcaaattc caaaacgaca
    23161 gcggatttac tacttattga aatgtatgac ggtaatgtag ttagagtacc gcagtcacaa
    23221 ctcacattga aacttcccta ttatcaaaaa ttgaaaaaaa accttgaaaa tgatagtata
    23281 gtggatatgg aagttggaat ttacactaca acacaggaga ttgaaaatca acctgaagtt
    23341 cctcttacgc cagaacaaaa cgcagctgat aaagaaggag ataagcctgg tgagcatcag
    23401 gaacagacag acaatgattc agaaacgcca gcaaatcaga gtagtcctca gcaagcacca
    23461 ccatccccag aaacggtcct cgaacaggcc catggctagc taatatctaa gttgaaaaag
    23521 caatgaaaac gttagaaatt caacgatt
//
LOCUS       DATWVB010000024        22691 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.024, whole genome shotgun sequence.
ACCESSION   DATWVB010000024 DATWVB010000000
VERSION     DATWVB010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22691
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.024"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(29..367)
                     /gene="cadX"
                     /locus_tag="VCX65_001116"
     CDS             complement(29..367)
                     /gene="cadX"
                     /locus_tag="VCX65_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HEP5053581.1"
                     /translation="MKKDSICQVGVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQ
                     INIIFYLLAVEELCVCDIACLLNLSMASASHHLRKLANQNILDTRREGKIIYYFIKDE
                     EIRDFFNQLG"
     gene            complement(379..993)
                     /locus_tag="VCX65_001117"
     CDS             complement(379..993)
                     /locus_tag="VCX65_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEP5053582.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKEGLSK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGETLEKYSRWFIAVVYLGLGMYILIENNSFDMLWAVLG"
     gene            complement(1286..1435)
                     /gene="rpmG"
                     /locus_tag="VCX65_001118"
     CDS             complement(1286..1435)
                     /gene="rpmG"
                     /locus_tag="VCX65_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEP5053583.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            complement(1451..1633)
                     /gene="rpmF"
                     /locus_tag="VCX65_001119"
     CDS             complement(1451..1633)
                     /gene="rpmF"
                     /locus_tag="VCX65_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEP5053584.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            1853..3133
                     /locus_tag="VCX65_001120"
     CDS             1853..3133
                     /locus_tag="VCX65_001120"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEP5053585.1"
                     /translation="MKLQKPKGTQDILPEDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRSAYRQTLIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGITLPIETEMDVYLA
                     VLGDSANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFANISEQLLS"
     gene            3471..5219
                     /gene="aspS"
                     /locus_tag="VCX65_001121"
     CDS             3471..5219
                     /gene="aspS"
                     /locus_tag="VCX65_001121"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEP5053586.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVNGIDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLIAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKGNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            5212..6153
                     /locus_tag="VCX65_001122"
     CDS             5212..6153
                     /locus_tag="VCX65_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP5053587.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIVTSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            6173..7051
                     /locus_tag="VCX65_001123"
     CDS             6173..7051
                     /locus_tag="VCX65_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP5053588.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVTGVLSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGFVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     EELGRGVTYLTGEGAYSGRRKKVIYVALGPRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            7094..7966
                     /locus_tag="VCX65_001124"
     CDS             7094..7966
                     /locus_tag="VCX65_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP5053589.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(7993..8301)
                     /locus_tag="VCX65_001125"
     CDS             complement(7993..8301)
                     /locus_tag="VCX65_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEP5053590.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQAIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKASHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(8389..10080)
                     /locus_tag="VCX65_001126"
     CDS             complement(8389..10080)
                     /locus_tag="VCX65_001126"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEP5053591.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKTKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHSVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            10371..10808
                     /gene="argR"
                     /locus_tag="VCX65_001127"
     CDS             10371..10808
                     /gene="argR"
                     /locus_tag="VCX65_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEP5053592.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            10805..11157
                     /locus_tag="VCX65_001128"
                     /pseudo
     CDS             10805..11157
                     /locus_tag="VCX65_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623648.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
     gene            11144..13699
                     /gene="mutS"
                     /locus_tag="VCX65_001129"
     CDS             11144..13699
                     /gene="mutS"
                     /locus_tag="VCX65_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEP5053593.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNL
                     KIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKILATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIISVPS
                     QVESSSAVRQGQLSLFGDEEKAHEIRQALEAIDVMNMTPLQAMTTLYELKKLL"
     gene            13828..15810
                     /gene="mutL"
                     /locus_tag="VCX65_001130"
     CDS             13828..15810
                     /gene="mutL"
                     /locus_tag="VCX65_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEP5053594.1"
                     /translation="MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTT
                     KKMLAISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQFRGLYYDPQKNDFFVKESAVSEKIPETDFYFGAV
                     DNSVKVEKAELLPHSEEVIGPSSVKHASRPQNTFIETDHPNLDLKNRQKLSQMLTRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            15821..17041
                     /locus_tag="VCX65_001131"
     CDS             15821..17041
                     /locus_tag="VCX65_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP5053595.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFVGILLVEIASNFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHGKGLLASFQNYRQVFHDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVP
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALL
                     GIYFTVVSAKMKKV"
     gene            17043..17639
                     /gene="ruvA"
                     /locus_tag="VCX65_001132"
     CDS             17043..17639
                     /gene="ruvA"
                     /locus_tag="VCX65_001132"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEP5053596.1"
                     /translation="MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
                     LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            17649..18209
                     /locus_tag="VCX65_001133"
     CDS             17649..18209
                     /locus_tag="VCX65_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEP5053597.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVAAFTSEEMADALENPSIIRHKLKLAATVNNAIA
                     VQKIQEEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            18278..19549
                     /locus_tag="VCX65_001134"
     CDS             18278..19549
                     /locus_tag="VCX65_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEP5053598.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
                     VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            19638..20774
                     /gene="recA"
                     /locus_tag="VCX65_001135"
     CDS             19638..20774
                     /gene="recA"
                     /locus_tag="VCX65_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEP5053599.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDRKVRVKFGLLEESEEESAMVVASEEIDDLALDLDNGIEIED"
     gene            21065..21463
                     /gene="spx"
                     /locus_tag="VCX65_001136"
     CDS             21065..21463
                     /gene="spx"
                     /locus_tag="VCX65_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEP5053600.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
     gene            21577..21846
                     /locus_tag="VCX65_001137"
     CDS             21577..21846
                     /locus_tag="VCX65_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEP5053601.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            21843..22262
                     /gene="ruvX"
                     /locus_tag="VCX65_001138"
     CDS             21843..22262
                     /gene="ruvX"
                     /locus_tag="VCX65_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEP5053602.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            22274..22579
                     /locus_tag="VCX65_001139"
     CDS             22274..22579
                     /locus_tag="VCX65_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEP5053603.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
BASE COUNT         6868 a         3852 c         4909 g         7062 t
ORIGIN      
        1 gaaaagtaga aagtagtaaa aatagttgtt atcctagttg attaaaaaaa tctctgattt
       61 cctcatcttt tataaaataa tatataattt tcccctctct tctagtgtcc aagatgtttt
      121 gattggctag tttacgaaga tggtgggagg cagatgccat actgagattt aataaacagg
      181 ctatatcgca gacacagagt tcttcgacgg caaggagata aaagatgata tttatctgtt
      241 tattatcggt aaattttgat aaaatacgaa gtgatttttg gactttttcc ttttcaaggt
      301 agttcgttgc ggttgtaaca ttttgttgat ttataacacc tacttgacag atactatctt
      361 ttttcataat tttttctcct agcctaacac agcccatagc atgtcaaagc tgttgttttc
      421 aatcaggata tacatcccca atcctaaata gacaacggca ataaaccatc tgctatattt
      481 ttccaaagtt tctccaacag aagggacttg tgccaatttt tgggcagaaa aaaccaagag
      541 ataaatcatg actagaaagg taagtaaagc cactatcaaa ttcgctaaat ttaaggtagt
      601 aaaatatggg acaaagacac caatattgtc agcaccacaa cttgcaaaag taatcatagc
      661 gactagaaaa atcaggtttt tattatcttt gctcaaacct tctttggcaa tagcttctcc
      721 atcagaatct cctaaaagca aaactttgag gcctaggaaa attggaatca aaccgagcaa
      781 acctaaaatc tctttactag gaatataatc taagacaaat gcaaaaagca aacttagcaa
      841 tattagacta acagagccta gaaattgtcc taaatagatg ttaatgatgt cttttctgct
      901 ttttcttttg gcaaaaaata acattaggat aataagtaag tctacggctg tcccagaata
      961 caggattatt gaagtaacaa cattttgaat cataaaacac ctcattcaaa tatatttttg
     1021 aatgaatttt aacattaaac tttgtagatg tcaatttcag ctacaccaaa atatagataa
     1081 gaagttagtg taccaaatat aaaaaagccc tgccatccaa atgataacag ggcttaactt
     1141 caatatccaa atgatatatt catctaaaaa aggtagagta aaaggtagag ttcttattga
     1201 tttatattac aatgtaatga acttcaaaaa ttcaaaaatc gcttaaaatc aacgttttga
     1261 cgtctaatga cgtgtagtga accccttact taacctctgt aaatgtaacg tgtttacgta
     1321 attttggtga gtattttttc aattgaagac ggtctggagt gttacgtttg ttttttgaag
     1381 taaggtacaa gcgttcacca gattctttat gttcaagtgt aatatttacg cgcatggtat
     1441 ctcccttcta ttatttagct tcgttagctt tagcgatttt acgtcctttg tagtatcctt
     1501 taagggatac acggtgagaa cgtgagtaat ctccagtagt ttcgtcgaat tgtacagatg
     1561 gagctgtcaa tttgtagtgt gtacgacgtt tgtttttctt cgcttttgac gtgtgacgtg
     1621 caggtactgc cattttctta ttcttccttt cgatgtgtaa gttttgattt tcatcaactt
     1681 cactatgata acatatcttt tttgtaaagt aaagttactt gacaaaactt tttattttta
     1741 caatttcatg gtgaaaatac tatcaaacta aagcaaatga tatatgcttg tttaaaatat
     1801 aagaaaaaat ggtagaatgt ttaaagagaa aactaatcaa agaggtaaac ttatgaaact
     1861 tcaaaaacca aaaggaaccc aggatattct tcctgaggat gctgcgaaat ggcagtatgt
     1921 ggaatctgtt gcgcgtgata cgtttagcca atacaattat ggagaaattc gtactcctat
     1981 gtttgaacac tacgaggtaa tctcgcggtc tgtgggtgat acgactgata ttgtgacgaa
     2041 ggaaatgtat gatttctatg ataaaggaga tcgtcacatt accttgcgac cagagggtac
     2101 agctccagtg gtacgttctt atgttgaaaa taaattgttt gcgccagagg tccaaaaacc
     2161 tgtcaaactt tattatatcg gttccatgtt ccgctacgaa cgccctcaag ctggtcgttt
     2221 acgtgaattt caccaaattg gagtagaatg tttcggtgct gctaatccag caacagatgt
     2281 tgaaaccatt gcgatggcct atcacctctt tgaaaaattg ggtattaagg atgtcaccct
     2341 tcatttaaat agtttgggga gccctgagag tcgttcagct tatcgtcaaa ccttgattga
     2401 ctacttaaca ccaatgcgtg atcaattatc taaagatagt caacgtcgct tggatgaaaa
     2461 cccactgcgc gtgcttgatt ctaaagaaaa agaagataaa ctagccgttg aaaaggcgcc
     2521 ttctattttg gattacttag atgaggaaag tcaggcgcac tttgaggcgg tcaaagatat
     2581 gcttgaagca cttgacattc cttatgtgat tgacaccaat atggtacgtg gccttgatta
     2641 ctataaccac actatttttg aattcatcac gtctgtggag ggctctgact taaccatctg
     2701 tgcgggtgga cgttatgata gtttggtagg ttattttggt ggaccagaaa cccctggctt
     2761 tggctttggt cttggtttag aacgtctctt gatgattatt gaaaagcagg gcattacctt
     2821 gccaattgag acagagatgg atgtttacct tgctgtgtta ggtgatagtg ctaatagcaa
     2881 agctttagaa ttggttcaag ccattcgccg tcaagggttt acagctgaac gagattacct
     2941 tggccgtaag attaaggctc agtttaaatc agccgatacc tttaaagcaa aattggtaat
     3001 gactttagga gaaagtgaag ttgaagcagg caaagctgtg attaagaata atcgtagtcg
     3061 tcaagaagtg gaagtcagtt ttgaagatat gatgacaaac tttgcaaaca tctcagagca
     3121 attattgtct taatgatttt attgtcgtca taagcttttg ttgatatgat tgtttagaag
     3181 ataatcacta aaacaggtgt aacttccctt tttagaaggg agttgcacct gtttgttttc
     3241 tgtaagggga ttgattagct ttcttagtat tctgtgagga cacctgatat gtcaaaatgc
     3301 tgacgactca gtattcttgc tttatcttta gaaaaactct ttttaaatgg gtggggtttt
     3361 taagggcttt ttgctataat agtagggaat gaattaattg atttatatag tgaaaggaat
     3421 tggaaacgag caggtttcac aggattctgt ttgttttagg gaatttattt atgaaacgta
     3481 gcatgtatgc agggcgtgtt cgcgaagaac acattggaac gacaatcaca ttgaaaggat
     3541 gggtcagtcg tcgtcgtgac ttgggtggtc tcatctttat tgatttacgt gaccgtgagg
     3601 gtgtgatgca attagtcatt aaccctgagg aagtttccag tgatgtgatg gcaactgctg
     3661 aacgcctacg tagtgaatat gtgattgaag tggaaggttt tgttgaagct cgacaacaag
     3721 ccaatgataa gttggcgaca ggaatggttg agttaaaagt atctgctttg accattttaa
     3781 acacagctaa aacgacgcct tttgaaatta aagatgacgt tgaagtaagt gatgacacgc
     3841 gtttacgtta ccgttactta gatttacgac gtccagaaat gttagaaaac ttcaagctac
     3901 gtgcaaaagt gactcattct atccgtaatt accttgatga ccttgagttt attgatgtcg
     3961 agacacctat gttgacaaaa tcaactccag aaggtgcgcg tgactatctg gtaccaagtc
     4021 gtgttagcca agggcatttc tatgctttgc cacaaagtcc gcaaattacc aaacagttat
     4081 tgatgaatgc tggctttgat cgctattatc aaattgtgaa atgtttccgc gatgaagatc
     4141 tacgtggtga ccgtcaacct gagtttacac aagttgactt ggaaacgtca ttcctttctg
     4201 aacaagagat tcaagacatc gttgaaggca tgattgctaa agtgatgaaa gagacaaaag
     4261 aaatagatgt aaccctacca ttcccacgta tgagctacga tgtagcaatg aatagctacg
     4321 gctctgataa accagacaca cgttttgaga tgcttttaca agacttgaca gtaactgtca
     4381 atggaattga cttcaaggtt ttctcagaag caccagctgt caaggcgatt gtggtgaagg
     4441 gaaatgcaga tcgatactct cgtaaagata ttgacaaatt aactgagttt gccaaacaat
     4501 ttggtgctaa aggccttgcc tgggttaagg tgacagatgg tcaattggca ggcccagtag
     4561 ccaagttctt gatagctatt gagacagagt tgtcaagcca attaaaactt gctgagaatg
     4621 atttggtttt atttgtagcg gatactcttg aggttgctaa taatacatta ggtgcgcttc
     4681 gtaatcgtat tgccaaggac cttgacatga ttgatcagtc gcagtttaat ttcctttggg
     4741 tggttgattg gccaatgttt gagtggtcag aagaagaagg acgttatatg tcagctcatc
     4801 accccttcac tcttccaacg ccagaatctg ctcatgagtt agagggtgat ttggctaagg
     4861 tacgggcaat tgcttatgac atcgttttaa atggttacga gcttggtggt ggtagcctgc
     4921 gtatcaatca aaaagagatg caagagcgca tgttcaaggc tcttggcttt accgctgatg
     4981 aagctaacga ccaatttggt ttcttactag aagcgatgga ctacggcttt cctcctcatg
     5041 gtggcttggc aattggtctt gaccgttttg tcatgttgct tgctggaaaa ggcaatattc
     5101 gagaagttat tgccttccct aaaaataaca aagcctctga tccaatgacg caagcaccta
     5161 gtcttgtttc tgaaaaccaa ttagaagaac tcagtcttca aatagaaagt catgattaag
     5221 aaaacaacct ataagaaaaa agttaaatat gtcattagta gaggggccaa gaaagttggc
     5281 ctactccacg ctctaagaag tatttcaaga gaaaaatatg cagagaagat ttcggcttct
     5341 ctgctttatg gcattctctc tagtattgct gtgaattttt tcttccagcc tgggcatgtt
     5401 tattcaagtg gagcaactgg tctagcacag gttttttcag ctcttagtca tcgtctttta
     5461 ggctatgatt ttcccatcgc ctttgcgttt tatttgatta atattccttt gcttatttta
     5521 gcttggtata aaattgggca tcaatttacc atttttacct ttatcacagt cagcatgagt
     5581 tctttcttta ttcaaatcat gcctcaagtg acgctgacga ctgatcctct tatcaatgct
     5641 atttttggtg gtttggttat gggaatggga attggtacag gtctcaaatc acgtatctct
     5701 agtgggggga ctgatattgt cagtttgacc cttagaaaac gaacaggcaa ggatgtgggc
     5761 agtctctcat tgatggttaa tggtgcaatt ttagcctttg cagggatttt atttggctgg
     5821 cagtacgccc tttattctat ggtctctatc tttgtatcaa gtcgtgttac ggatgccatt
     5881 ttcaccaagc aaaagaaaat gcaggcaact attgttacca gccatccaga gcgtgtgatt
     5941 catatgatcc ataaacgtct gcatcgcggg gtgaccagta tcaacgacgc agaagggact
     6001 tacaagcatg aacaaaaagc agttttgatt accattttga catgtgaaga atacccagaa
     6061 ttcaaatggc tgatgttaaa aacagaccca caagcctttg tttcagtggc tgagaatgtt
     6121 agaattatcg gtcgttttgt ggaagatgat taagaaaaac acaggaggtg tcatgtcaat
     6181 tgaccaacgt ttacagttaa agaaattttg ctttattatt ttaggagctg ctatctacgc
     6241 ctttgctttt gtttattttt acatggctaa tcgcattgca gccaatggtt tagctggtct
     6301 caccctagtt ggtaaggcac tttttgagat tgatccttct ttgataggct atttgattaa
     6361 tttgcctttg gtcttgctgg gagctagatg ttttgggaaa agagccatgg tttacacagt
     6421 aacgggtgtt ttatcacttt acttttttgt gtggctgttt caacgctttc ctttggtcgt
     6481 tgacttggac catgacaatt tagtcgtttc cttgatggct ggaattattg gtggtctagg
     6541 tggcggtttt gtgtttcgca atggtggaac catcggtgga gcagatatta ttgctaagtt
     6601 attagaagac aagttaggac tacagctgaa tcaagctctt ttaggcattg atctttttgt
     6661 catgattgtc tctttgactt atatttccct gccgcaaatg atgtatgctc tgattgctag
     6721 ctttatgtat ggtcaaattg ttcgcttggt acaacaaggt ggttattcag cccgtggcat
     6781 ttttatcgtt tcagaacaag cggagaaaat tgcccggttc atcatggaag aattgggaag
     6841 gggagttact tatctaacag gtgaaggagc ctactctggt cgccgtaaaa aagtgattta
     6901 tgtggctttg gggccaagag atattaggga attaaaagct tttttaactc aggttgatcc
     6961 taatgccttt atcacttatt ttgatgttaa tgaagttaat agcccagaat ttttaactat
     7021 taaaagcaaa taccataaaa agagaaaata aatgagcatt agagttgcct gcgaagaata
     7081 gtgaggataa aggatggcac atcacgataa attgactaaa ctactaaaac tgtttttgat
     7141 tgccctaggt gtagccattt ataccttcgg ttttgttaat tttaacatgg ctaatgcttt
     7201 ggctgaaggt ggtgtggcag gaataacctt gattttacac gcgcattttg ggattaatcc
     7261 tgcttactct tctctcttat ttaatcttcc actttttatt ttaggggcaa agatttttgg
     7321 gaagcgttct ttggctctaa ccatctatgg aacagttctg atgtccgctt ttatctggat
     7381 gtggcaaaaa gttcctatcg aacttggctt ggaaaatgac atgatgttgg tggctgtagt
     7441 ggcaggtctc ttttcaggga ttgggagtgg cattgttttt cgctatggtg caaccacagg
     7501 tggaacggat attattggtc gcattgcaga agaaaaattt ggagctaagc taggtcaaac
     7561 tttgcttttg gtggatgctc ttgtattgac agcttcgttg acttatgtgg atttaaaaca
     7621 catgctttat actttggtgg caagctttgt ttttagccaa atgattagtg tggttcaaaa
     7681 tggtggttac actatccgtg gaatgattat tattaccaag cattcagagg ctgccgctca
     7741 agctatccta accgaaatca atcgtggagt gacttacttg aaaggtcaag gagcttactc
     7801 tggtaatgat tacaatatca tgtatgtgac cttgaaccca actgaagttc gggaagtcaa
     7861 acgtatttta gctggtttgg atccagatgc ctttatctcc attattgatg tggacgaagt
     7921 tattagctct gattttaaaa ttcgccgaag aaattatgat aaataaaaat acaggtcaaa
     7981 cagcctgtat ttttattttg gtcccccact taagaaacta ccaagcataa tagctgatat
     8041 agcagttccc ttgtaatggc tagcttttgt ttttaccaag cgactaagat caaatatgct
     8101 tttaggagca tcaaattgat gtgttaagat gtattgattg ataagtgagt caatttttgt
     8161 agctaggagt gagctcatcc cctctttttc aagttgactg gcgagctcga agatcgcttg
     8221 acgaaaataa tcatcggctt gtattacttg ttcgctataa actttactaa gagcatctaa
     8281 tatttctttt tctgatggca tggcattctc ctgtaacata ttgtgctatt attataatat
     8341 aaaaaactaa gactgtcata aatgtgacag ccttagtaat gttattactt acatttcatt
     8401 tggtgcgtca acaccgagta agcgaagcgc ttctttaaga acagtagcag ttgcatagca
     8461 gagagctaag cggttatcac gttctgagtt gtcgtcaaga atgcgagtgt gagcataata
     8521 tttgttaaag ctttgggcta agttaatagc aaatttagcc ataatagaag gctcaaagtt
     8581 atctgatgtt cgcttgataa tgcgtgggaa atcttggata agtttgataa tttcccagct
     8641 ttcagcatca gctaaactgt aagtggtggt tgcagatggc gtaaagtcag ctttacgtag
     8701 aatagattgg atacgagcat gagcatattg aacgtaaggt ccagtttctc cttcaaagga
     8761 aaccatggct tcaaggtcaa agtcataccc attcatacga tctgttttga gatcgtaaaa
     8821 cttgatggca ccgacaccaa cagagtgtgc aacggcttct ttgtcagcaa ggtttggatt
     8881 tttcgcttca atttgagaag ctgcacggtt aatggcttca gcaaccgtag gttcaagaag
     8941 aataacatta cctttacgtg ttgataattt agcaccgcct tttgtgacaa gtccaaaagc
     9001 aacgtgtgtc atatcatctg accaatcgta acccatttct tttagcactg cttttaattg
     9061 tttgaagtga gcagcttgct cattaccaac aacataaacg gatttagcaa agtcataagt
     9121 gcgtttacgg taaagtgcgg cagctaggtc acgggtaatg taaagagtag cgccatctga
     9181 ttttttgatc aaggcagggt gttcaatgcc atatttttca agattaacaa cttgggcacc
     9241 tttagattct acaagaaggt ttttagcttc taataagtca agaacctcat ccattttgtc
     9301 attatagaag gcctcaccgt tgtaactatc gaaggtgaca tgtaattggt cataaagtcg
     9361 gttgaactca agtaaacttt catcacggaa ccattgccat aattcagtag cttctttgtc
     9421 gccatcttcc aatttacgga accattcacg agcttcttca tcaacggtgg gatcagtttc
     9481 agcttcagca ttgatacgaa cgtaaagttt taagagttca tcaataggat gtgcctgaac
     9541 agcagcttca tctccccatt ttttgtaggc aacaatgagc ataccaaatt gtttacccca
     9601 gtcaccaagg tgattgattt ttacaggttt atagcccatt ttggcaaaaa tgtgagcgag
     9661 actatcacca ataactgttg agcggaggtg accgattgaa aatggcttag cgatgtttgg
     9721 gcttgacatg tcaatagcaa catttcgccc ttgaccttcg tcttgctgag catagtctga
     9781 acctgctgta atcacttgtt caaggacctg tgaggaaatc ttagttttat caaggaaaaa
     9841 gttgatgtaa gggccgacag ctacgacttt ttcaaattgg ctctcatcaa tctgttcagc
     9901 taactcgcta gcaatcattt gaggggcttt gcgaaggact tttgctaaac taaaggctgg
     9961 aaaggcaagg tctcccatgt cagaattttt tggggtttca agcaagttaa aaatagcatc
    10021 ttgttctaat tctggaacaa ctttagctat ttcacttgcg attagagttt tagtatccat
    10081 acagcgtctc ctaaaaattg tttgtcaccc tattctaaca tatttcttta aaataaacga
    10141 ggagaggatt gataaattat actgaaactt tcaaggaaat gaattgcttg aggttgttgt
    10201 ttttctgaaa atgttataaa aagagaaatg aggtttcttt tcaacagttt tcaagtgaaa
    10261 ttctagttga atttgctaaa aaattgctga aaatagctgg gcgaagatga aataatacac
    10321 tttttttgtt ataatttgag aggataatta tacaattgga gtgatatatc atgaataaaa
    10381 tggagcgtca acagcagatt aagcgaatca ttcaagcaga gcatattggc acacaagaag
    10441 atattaaaaa tcaccttcaa aaagaaggca ttgtggtcac ccaagcaact ctatctcggg
    10501 acttaagaga aattggcctt ttgaaattga gagatgaaca aggcaaactc tattatagtt
    10561 tgtctgaacc cgttgcaaca ccatttagtc ctgaggtgcg tttttatgtt ttgaaagttg
    10621 atcgagcagg ttttatgctg gttctccata ccaatttagg agaggctgat gttctagcta
    10681 atttgattga caatgatgcc attgaagata ttctaggaac cattgctggt gcggatacct
    10741 tgcttgtgat ttgcagagac gaagagattg ctaaacgctt tgaaaaagat ttggctgcag
    10801 gcctatgact agctattaag agtctttgac acaattgatt cttgctatcc atgaattcta
    10861 gtatcgttgc ttataaagaa gtgcagcaat agctgtctaa gctccgtgat tttaaaaagt
    10921 aagcttatca gatgaaacgc tatcaacaag atgccctgct tttcaaaaaa aatagataaa
    10981 gaaaaggctg cgacagtatc tgcaagcagg gcaaaagaac tagaagatag gctcagtcat
    11041 cagccattaa ttgatgatta tcgagaaaag atgcaagatg caagtgatgt gattcagtat
    11101 atcaccaaac gtatagaaga tcagttaaac aaggagttaa caaatggcaa aaactaacat
    11161 ttctcctgga atgcaacagt atctggacat caaaaaagat tatccagatg cttttttgct
    11221 ttttaggatg ggtgactttt atgaattatt ttacgaggac gctgtcaaag cagcacaact
    11281 cttagaaatt ggtttgacca gtcgcaacaa gaatgcggaa aatccaattc ctatggcagg
    11341 cgtgccacat cattctgccc aacaatacat tgatgtgtta attgagttgg gttacaaggt
    11401 tgctgtcgca gaacaaatgg aagacccaaa gcaagctgtt ggggtggtga agcgtgaggt
    11461 cgttcaagtc ataactcctg gaacggttgt ggattcagct aagccagata gcgccaataa
    11521 ctttttggta gctgttgact ttgatggttg ccgttatgga ttggcttata tggatgtgtc
    11581 cacaggtgaa ttttgcgtga cagatttggc ggactttacg agtgttcgta gcgaaatcca
    11641 aaacctcaag gcaaaagaag tcttactagg ttttgattta tctgaagaag aacagacgat
    11701 tttggtcaag cagatgaatt tgctgctttc ttatgaagaa acggtctatg aagataaatc
    11761 tttaattgac ggccaattga caacggtaga actgacagcg gcaggaaaac tcttgcaata
    11821 cgttcacaaa acacaaatgc gagaactcag ccacttgcaa gcattggttc actatgagat
    11881 caaggattat ttgcagatgt cgtatgccac taagtcaagt ttagatttgg tagaaaatgc
    11941 taggactaat aaaaaacatg gaagtctcta ttggctgtta gatgaaacca agacagctat
    12001 ggggatgagg cttttgcgct catggattga tcgacctttg gtttctaaag aagctatttt
    12061 agagcgtcaa gaaattattc aagtttttct gaatgctttt attgagcgaa ccgatttaag
    12121 caatagttta aaaggtgttt acgacatcga acgcttatct agtcgcgtgt cttttggtaa
    12181 ggcaaatccg aaagatttac ttcaattggg gcatacctta gcccaagtgc cttatatcaa
    12241 agctatctta gagtcttttg acagtccttg tgttgacaaa cttgtcaatg atattgacag
    12301 tttgcctgag ttggaatact tgattagaac agccattgat ccagatgcac cagcaactat
    12361 tagtgaaggc agtattattc gtactggttt tgatgagcgc ttggaccatt atcgtaaagt
    12421 gatgcgagaa ggaacaggtt ggattgcgga tattgaggct aaagagcgtc aagcaagcgg
    12481 cattaataac ctaaaaattg attacaataa aaaagatggt tattattttc acgttacgaa
    12541 ttcaaatctt agcttagttc ccgagcattt tttcagaaag gcaactttaa aaaattctga
    12601 gcgttatgga acagcagaat tggctaagat tgaaggtcag atgttagagg ctagggaaga
    12661 gtcatctagt ttagaatacg atatttttat gtgtattcga gctcaagttg aaacctatat
    12721 taatcgttta cagaaactgg ctaaaatttt ggcaacggta gatgttttgc aaagtttagc
    12781 agtcgttgct gaaaccaatc attatatccg gccgcagttc aatgataatc atgtgattac
    12841 aattcaagaa ggtcgtcacg cggttgttga aaaggttatg ggagtgcagg aatacattcc
    12901 caatagtatc tcttttgacc aacagaccag tattcagctg attacaggtc caaatatgag
    12961 tggtaagtcg acttatatga gacagctggc cttaacggtt atcatggccc agatgggttc
    13021 atttgtggct gctgaccatg ttgatttacc tttatttgat gcgattttta cgcgtattgg
    13081 ggctgctgat gatttgattt ctgggcaatc aacctttatg gtggagatga tggaagcaaa
    13141 ccaagcaatc aaacgcgcaa gtgacaactc tcttattcta tttgatgaac tgggacgagg
    13201 tacggcaact tatgatggta tggctttagc ccaggcaatt attgaatata tccatgatag
    13261 agttggtgct aagaccatat ttgcaacgca ttatcatgaa ttgacagact tgtcaactaa
    13321 gttgacaagt ctagtcaatg ttcatgtagc aacgcttgaa aaagatggcg atgttacctt
    13381 ccttcataag attgctgagg gaccggcgga taaatcttac ggtattcatg tggcaaaaat
    13441 agcaggactg ccaaaatccc tattaaagag agcagacgaa gttctgaccc gtttagaaac
    13501 acagtcacga tctactgaga taatatcagt cccttcacaa gttgagtcaa gcagcgctgt
    13561 tagacagggg caattatccc tttttggtga tgaagagaaa gctcatgaga ttaggcaagc
    13621 actggaagct attgatgtca tgaacatgac cccgcttcaa gcaatgacaa ccctttacga
    13681 attgaaaaag ttgttatagt ctttcagctg aaaatgaaaa agatgctttc tatattgaag
    13741 gcatcttttt gttctgtcaa aaacggtccg aggccttcgg ctatttatta agtgtgttat
    13801 aatagtccat aagaatgcga ggaaattatg acaaacatta ttgaattacc ggaagttctc
    13861 gccaaccaaa ttgcagctgg tgaagttgta gaaaggccag cgagtgttgt caaggaattg
    13921 gttgagaatg ctattgatgc taaaagtagc cagattaccg ttgaaattga agagtctggc
    13981 cttaagatga tacaggttac agacaacggt gagggaatgt ctcatgaaga tttaccttta
    14041 agtctgcgtc gccacgctac tagtaaaatt aagagtcaga gtgatttgtt tagaattaga
    14101 acacttggct tccgtggaga ggctttaccg tctgttgcct ctatcagtaa aatcacgata
    14161 aaaacagcaa caaaagaagt cactcacggt tctcttctta tagctactgg tggggaaatt
    14221 gagacacttg aagcgatctc aactcctact ggaaccaaaa ttaaggttga aaaccttttt
    14281 tacaacacgc ctgctcgtct caaatatatg aaaagtttac aggcagaatt agctcacatt
    14341 gtagatgtgg tcaaccggtt gagtttggca catccagaag ttgctttcac actgattagt
    14401 gatggtcgcc aattaactca gacatcagga actggcgatt tacgccaagc aattgcaggg
    14461 atctatggtt tgaatactac caaaaaaatg ctggctatct ctaatgctga tttggatttt
    14521 gaagtttccg gctatgttag cttgccagag ttgacacgcg ccaaccgtaa ttacatgacg
    14581 attttggtta atgggcgtta catcaagaat ttcttgctta atcgagcaat tcttgatggt
    14641 tacggttcta agctcatggt tggacgtttc ccaattgttg tgattgatat tcagattgat
    14701 ccctatttgg ccgatgtcaa tgttcatccc acaaaacaag aggttcgtat ttcaaaagag
    14761 cgtgagttga tggctttaat tagtacggcg atttctgaaa gtcttaagga acaagatttg
    14821 attccagatg ctctggaaaa cttagccaaa tcaagcacac gacatttctc taaaccagag
    14881 caaacacaac ttcctttaca gtttagggga ctttattatg atcctcaaaa gaatgacttt
    14941 tttgtcaaag agtcggctgt ctcggaaaaa atacctgaaa ctgattttta tttcggcgct
    15001 gttgacaaca gtgtaaaggt tgaaaaagca gagctgttac cccactcaga agaagttata
    15061 ggaccttctt cggttaaaca cgcaagtcgt ccccagaata cctttatcga gactgatcat
    15121 cctaatcttg acttaaaaaa cagacaaaag ttatctcaaa tgctaacccg tttggaaaat
    15181 gaagagcaat cagtgtttcc cgaattggat tattttggtc agatgcacgg aacttatctc
    15241 tttgctcaag gtaaagatgg cttatttatt atcgatcagc atgctgctca agagcgggtt
    15301 aaatacgaat attatcgtga taagataggt gaggttgaca gtagtttaca gcaattgttg
    15361 gtgccctatt tgtttgagtt ttctggttct gatttcatta acttacagga gaaaatggca
    15421 ctcttaaatg aagttggtat cttcttagaa gtttatgggc acaatacttt cattttgagg
    15481 gagcatccta tctggatgaa agaagaagag attgcatctg gtgtctatga aatgtgtgac
    15541 atgttacttc taaccaatga ggtatctatt aaaacttacc gagcagagtt agctattatg
    15601 atgagttgta aacgatctat caaggcaaat catagcttgg atgattattc agcaagaaat
    15661 ctgctactgc aattggccca atgtcaaaat ccttataact gccctcatgg tagacccgta
    15721 ttgattaatt ttagtaaggc agatatggaa aaaatgttcc gtcgtatcca agaaaatcac
    15781 actagcctgc gagagctagg aaaatattag agaggatgag atgcaagagt ttttaaatct
    15841 tcctaagcag attcagctga ggcaactggt acgctttgtg accattacct taggcagtag
    15901 tatttttccc tttatggcca tgtattatac gacttacttt ggtacgtttt ggacaggcct
    15961 cttaatgatg attaccagtt tgatgggatt tgttggaact ttatacggtg ggcatctgtc
    16021 agatgctctt ggtcgcaaaa aagtcattat gattgggtca gtaggaacaa cactaggctg
    16081 gtttctgact attttagcta atttgcctaa tgcagctatt ccttggttaa cctttgtggg
    16141 tattttattg gtagagattg cttctaattt ttatggtcct gcctatgaag ctatgttaat
    16201 tgatttgact gatgagagta atcgtcgatt tgtttacacc atcaattatt ggtttatcaa
    16261 tattgccgtc atgtttggtg cagggctatc tgggcttttt tatgaccatc attttttagc
    16321 cttgttagta gccttattac tcgttaatgt actttgtttt ggcgttgctt actactattt
    16381 tgatgagact agaccagaaa cacacgcttt tgaccatggt aaaggattac tggcgagttt
    16441 tcagaactac cgtcaggtgt ttcatgatcg tgcctttgtc ttgtttacct taggtgccat
    16501 cttttctggt agtatttgga tgcagatgga taactatgtg ccagtccatt tgaaactgta
    16561 ttttcagcca acggctgtgt taggtttcca agtaactagt tctaaaatgt tatcattaat
    16621 ggttttaact aatacattgc tgattgtcct tttcatgaca gtagtaaata aattaacgga
    16681 aaaatggaaa ctattacctc agcttgtggt tggttcttta ctatttactc tagggatgct
    16741 cttggcattt acctttacgc agttctatgc tatttggcta tcagttgttt tgttaacttt
    16801 tggggaaatg ataaatgttc ctgctagtca agtcctacgt gctgatatga tggatcattc
    16861 ccaaatagga tcttatacag gttttgtgtc aatggcacaa cccctaggtg ctattttggc
    16921 tagtctacta gtatctgtca gccattttac aggtccttta ggtgtgcaat gcttatttgt
    16981 agtcattgct ttgctaggga tttattttac ggttgtttct gcaaaaatga aaaaggtgta
    17041 gtatgtacga ttatattaaa ggtcaattga ccaaaattac ggcaaaatac attgtcgttg
    17101 aaacaaatgg actaggctat attatcaatg tagccaatcc ttatagcttt acagatagtg
    17161 tcaaccaact ggtaactatt tacctgcatc aagtgattcg tgaggatgct cacttgttgt
    17221 ttgggtttca tacggaagac gaaaaagatg tttttctgaa attaatttct gtatctggca
    17281 ttggccccac aacagctctt gctattgtgg cagttgatga taatgaggga cttgtgaatg
    17341 ccattgataa cagtgacatt aagtacctaa tgaaatttcc taaaattggt aaaaaaacag
    17401 cgcagcaaat ggttcttgac ttagctggca aatttgtgga ggctccacaa gagactggta
    17461 ataccaaagc gcgcagcaat aaagcaggca atactcaact ggacgaagcg attgaagccc
    17521 tccttgccct cggttataag gcagcggaat tgaagaaaat tcgtgccttc tttgaaggaa
    17581 cctctgaaac ggccgaacaa tacatcaaat cagcccttaa actattaatg aaaggctagg
    17641 tgtttcacat gaaacgttgt tcatgggttc ctaaggataa ccagctttac tgtgattacc
    17701 acgatttaga atggggtcaa cccctacatg atgatagaga tttttttgaa ttactctgcc
    17761 ttgaaagtta ccagtcaggc ttatcctggc tgactgtttt gaaaaaacgc caagctttca
    17821 gaactgtttt tcatcattac gacattgcat cggttgcagc ctttacctcg gaggaaatgg
    17881 ctgacgcttt agagaatcca tccatcattc gccacaagct aaagctagca gcaactgtca
    17941 acaatgctat cgcagtacag aaaattcaag aagagtttgg tagtttttca acttatctct
    18001 ggaattttgt tgggggaaag ccaattaaca accttgtcaa tcaagagaat cttgttcctg
    18061 ctcaaacaga attatctatt cgcttagcta aggatttaaa gaaaagagga tttaaatttt
    18121 tagggcctac aacggtttat tcttttatgc aagcatcggg tctggtaaat gaccatgaag
    18181 aggcttgtgt tttcaataga atcttctaat tcttcgtgaa ttggaagatt ttttgataaa
    18241 atgagatcag attacgaata gataagtagg tggggaaatg aaagctgaac tgattgcagt
    18301 aggtaccgaa attttgactg gtcaaattgt gaataccaat gctcaatttc tgtcggaaaa
    18361 aatggcagag ctaggtattg atgtctattt tcaaacggct gttggggaca acgaggagcg
    18421 tttactttca gtgattacaa ctgctagtca gcgtagtgac ttggtaattt tatgtggtgg
    18481 ccttggtcca acgaaagatg atttaaccaa acaaacttta gcaaagtacc ttaggaaaga
    18541 cttggtttat gatgagcaag cttgtcagaa actagatgac ttttttgcta agcgcaagcc
    18601 ttcatcacgg acaccaaata atgagcgaca ggcacaagtg attgaagggt caatcccttt
    18661 gccaaataaa actggtcttg cggttggtgg gttcatcaca gtcgatggta ttagttatgt
    18721 tgtcttaccg ggtcctccaa gtgaattgaa gccgatggta aatgaagaat tggtaccact
    18781 tctgtcaaaa caatacagta cattgtattc aaaggtacta cgcttttttg gtattgggga
    18841 aagtcagttg gtaacagtct tgtcagattt tattgagaat caaactgatc caaccattgc
    18901 tccgtatgct aagactggcg aagtgactct tcgcttatca acaaaaactg aaaaccaagc
    18961 tctggcagat aaaaagttag gtcagctaga agcgcagcta ctatcccgaa aaactcttga
    19021 aggtcaaccc ttagctgatg tcttttatgg ctatggggag gataattcct tagcgcgtga
    19081 gacatttgag ctcttagtaa aatatgataa gacaattaca gcagcagaaa gtctaaccgc
    19141 gggattattt cagtcaactt tggcgagttt tccaggagct tctcaagtat tcaatggagg
    19201 ctttgtgact tatagcatgg aagaaaaagc gaaaatgcta ggccttcctt tagaggagtt
    19261 gaaatcgcat ggcgttgtta gtgcttatac agccgagggg atggcggagc aagcaaggtt
    19321 attgactggt gctgatattg gggtaagttt aacaggtgtt gccggaccag atatgttgga
    19381 ggaacagcct gcaggtacag ttttcattgg ccttgccact caaaataagg tagaatcaat
    19441 aaaggttttg attagcgggc gaagtcgttt ggatgtgcgc tatatcgcta ctttacatgc
    19501 ctttaatatg gtccgtaaaa ctttattaaa acttgagaat ttgctataat gttatttagt
    19561 agctatagta ggatatggtt tacgattatg tagattaatc ctgctgacga tggtttgtta
    19621 aaaaagagga gaaagtattg gcaaaaaaat taaaaaagaa tgaagaaatc actaagaagt
    19681 ttggtgacga acgtcgcaaa gcccttgatg atgctttgaa aaatattgaa aaagattttg
    19741 gtaagggcgc agtgatgcga ttaggagaac gtgcagagca aaaagttcag gttatgagtt
    19801 caggaagtct agctcttgat attgcgcttg gagctggtgg ttatcctaaa ggacgtatca
    19861 tcgaaatcta tggtccagag tcttccggta aaacgactgt ggctttacat gctgtagcac
    19921 aagctcaaaa agaaggtgga atcgcagcct ttatcgatgc cgagcatgcg cttgatccag
    19981 cttatgctgc tgcgcttggg gttaatattg atgaactcct cttgtctcaa ccagattctg
    20041 gagaacaagg acttgaaatt gcaggtaaat tgattgattc tggtgcggtt gatctggttg
    20101 ttgtcgattc agtagcagct ttagtgccac gtgctgaaat tgatggtgat attggcgata
    20161 gccatgtcgg attgcaagca cgtatgatga gtcaggctat gcgtaaatta tcagcttcta
    20221 ttaataaaac aaaaactatc gctatcttta ttaaccaatt gcgtgaaaaa gttggtgtca
    20281 tgtttggaaa tcctgaaaca acaccaggtg gtcgagcttt gaaattctat gcttctgttc
    20341 ggttggatgt gcgtggaaca actcaaatta aaggaactgg tgaccaaaaa gatagcagca
    20401 ttggtaagga gaccaaaatc aaggttgtta aaaacaaggt cgctccgcca tttaaggtag
    20461 cagaagttga aatcatgtat ggggaaggta tttctcgtac aggggagctt gtgaaaattg
    20521 cttctgattt ggacattatc caaaaagcag gtgcttggtt ctcttataat ggtgagaaga
    20581 ttggccaagg ttctgaaaat gctaagcgtt atttggccga tcatccagaa ttgtttgatg
    20641 aaatcgaccg taaagtacgt gttaaatttg gtttgcttga agaaagcgaa gaagaatctg
    20701 ctatggtagt agcatcagaa gaaatcgatg atcttgcttt agatttagat aatggtattg
    20761 aaattgaaga ttaaaaagag cccttcaggg ctttttaaaa tgtattttta aaggttagta
    20821 ggactactat tcataggtgt gtgggtgaat agaaaccatc atttaaaaag atgtgagaga
    20881 gcagaactta ggttaactga tataaaatta aaataactaa taattcaagg gaatacaggt
    20941 gaaaaacctt attttaccaa gataatatct ttaaaattaa aaaaataggt ccaaagacct
    21001 atatttatag ataagaaact gtgctacaat aaagctatca cgaaatagaa agtgagtcag
    21061 caacatgatt aaaatttaca cgatttcaag ttgtacgagc tgcaagaaag ccaaaacttg
    21121 gctaaatgcc cataagcttg cttataaaga acagaactta ggaaaagaac cgctaactaa
    21181 agaagaaatt ttagcaattt tatcaaaaac cgaaaatgga gtggagagca ttgtttcatc
    21241 taaaaatcgt tatgccaaag ctctcgattg cgatattgaa gaactaagtg ttagtgaggt
    21301 tattgatttg attcaagata acccgcgcat ccttaaaagt cccattttga ttgatgataa
    21361 acgtctgcaa gtaggctaca aagaagacga tattcgtgct tttttacctc gctctattcg
    21421 taatattgaa aatactgaag cacgattacg tgctgcactc taaaagctct tgtagagctt
    21481 ttttttaaat accttcttcg cttgaaattc ttgtttattt aatagaaata agctataata
    21541 aagcatagca cttaatttta gaaagaaggt gtaagtatgg gatttacaga tgaaacagtc
    21601 cgctttaagt tggatgatgg cgacaaacga caaattagtg aaacattaac agcagtctat
    21661 cattcacttg atgaaaaggg ttataatcca attaatcaaa ttgttggtta tgtcttgagt
    21721 ggggacccag cttatgttcc tcgttataat gatgctcgaa atcagattcg taaatatgaa
    21781 cgtgatgaaa ttgtagaaga acttgttcgc tactatttac aaggaaatgg aattgatgtt
    21841 aaatgagaat aatgggactt gatgttggct cgaaaacggt tggtgtagct attagtgatc
    21901 ctcttggctt tacagcccaa ggacttgaaa ttatcaagat tgatgaggaa aaagcagaat
    21961 ttggctttac acgtttagaa gagcttgtta agcagtacca agttgaacag tttgttattg
    22021 gattgccaaa aaatatgaat aacaccaatg gtccacgtgt tgatgcaagt ataacttatg
    22081 gaaaccacat agagcacctc tttggacttc cagtccatta tcaagatgaa cgattgacga
    22141 ctgttgaggc agagcgtatg cttattgagc aagctgacat tagtcgtggt aagcgaaaaa
    22201 aagtcattga taaattagct gcacaactca ttttacagaa ctatttaaat cggaattttt
    22261 aaggagataa aaaatgacac ataatcatga aaatgaccac caacacgaag ttatcacact
    22321 tgtggatgaa caaggaaatg aaaccttgtt tgaaatttta ttaacaattg acggtcgtga
    22381 agagtttggt aaaaattatg ttctcttggt tccagcggga tctgaagaag atgagtctgg
    22441 tgaaattgaa atccaagcct attcatttac tgaaaatgaa gatggtactg aaggggattt
    22501 acaaccgatt cctgaggatt cagatgctga atgggatatg attgaagagg tatttaatag
    22561 ttttctagat gagaactaaa ttgttagtga cactatgtta aaaagtagcc gtgagggcta
    22621 tttttttaat gttattttcg aataaataag caggaggtga taatgataaa agaattaaat
    22681 gataaattta t
//
LOCUS       DATWVB010000025        22501 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.025, whole genome shotgun sequence.
ACCESSION   DATWVB010000025 DATWVB010000000
VERSION     DATWVB010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22501
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.025"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(153..2168)
                     /gene="recG"
                     /locus_tag="VCX65_001140"
     CDS             complement(153..2168)
                     /gene="recG"
                     /locus_tag="VCX65_001140"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEP5053604.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENRSETNGLPILYSKHAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSIIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     YKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAQNIRKKEVYD"
     gene            complement(2543..3997)
                     /locus_tag="VCX65_001141"
     CDS             complement(2543..3997)
                     /locus_tag="VCX65_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053605.1"
                     /translation="MERLGGADLDYCYHNHHDTAMISAEQLVFTYHDQKNPACQVSTC
                     QIASGQFIVLCGPSGSGKSTFLKLLNGIIPDYYAGKYEGRLDVADCQADRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQDLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAAGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            complement(3934..4614)
                     /locus_tag="VCX65_001142"
     CDS             complement(3934..4614)
                     /locus_tag="VCX65_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEP5053606.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWHFPEVWLLTLAVMCRFIPMIRQECCVIHRSLTIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            complement(4611..5204)
                     /locus_tag="VCX65_001143"
     CDS             complement(4611..5204)
                     /locus_tag="VCX65_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEP5053607.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPIVLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSAFAHYLLKKHFIKSGLLS"
     gene            complement(5201..6871)
                     /locus_tag="VCX65_001144"
     CDS             complement(5201..6871)
                     /locus_tag="VCX65_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053608.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLSVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQDISDESIWNLA
                     ETCGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACADHLFCVKNGSLKEVNKK"
     gene            complement(6864..8627)
                     /locus_tag="VCX65_001145"
     CDS             complement(6864..8627)
                     /locus_tag="VCX65_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEP5053609.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLLLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQAIERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDIQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLLQETINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLNTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            complement(8624..9460)
                     /locus_tag="VCX65_001146"
     CDS             complement(8624..9460)
                     /locus_tag="VCX65_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053610.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDLQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNDIRTQRRDRNK
                     NR"
     gene            complement(9457..10479)
                     /locus_tag="VCX65_001147"
     CDS             complement(9457..10479)
                     /locus_tag="VCX65_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEP5053611.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYGAIVKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            complement(10481..11365)
                     /gene="isdE"
                     /locus_tag="VCX65_001148"
     CDS             complement(10481..11365)
                     /gene="isdE"
                     /locus_tag="VCX65_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEP5053612.1"
                     /translation="MIKRCKGIGLALMAFFLVACVNQHHKTAKESEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSANPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHS"
     gene            complement(11349..12224)
                     /locus_tag="VCX65_001149"
     CDS             complement(11349..12224)
                     /locus_tag="VCX65_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEP5053613.1"
                     /translation="MTKVVIKQLLQVIVVFMISLSTMTGVVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQEVKDNQKPVDTKLGESQDESHTGAMITQNK
                     PKANSSNNKSLSDKKILPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKRKKNDKTM"
     gene            complement(12421..16248)
                     /gene="shr"
                     /locus_tag="VCX65_001150"
     CDS             complement(12421..16248)
                     /gene="shr"
                     /locus_tag="VCX65_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEP5053614.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKINANLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKTVPQN
                     QGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDVTITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLKKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     IEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVDEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVEKGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVSYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            complement(16738..18249)
                     /locus_tag="VCX65_001151"
     CDS             complement(16738..18249)
                     /locus_tag="VCX65_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP5053615.1"
                     /translation="MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSNNKA
                     EAENQVDDKSTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEARTPIQSLSPY
                     VSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYD
                     STRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQ
                     ASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSG
                     KRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSY
                     AWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGAD
                     GTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN"
     gene            complement(18336..19436)
                     /locus_tag="VCX65_001152"
     CDS             complement(18336..19436)
                     /locus_tag="VCX65_001152"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEP5053616.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANAIT
                     VTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKAVNLLIDSLKELGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            complement(19433..19789)
                     /locus_tag="VCX65_001153"
     CDS             complement(19433..19789)
                     /locus_tag="VCX65_001153"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEP5053617.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLSYLAGRWAGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            complement(19905..22424)
                     /gene="secA"
                     /locus_tag="VCX65_001154"
     CDS             complement(19905..22424)
                     /gene="secA"
                     /locus_tag="VCX65_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEP5053618.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMVSLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
BASE COUNT         6933 a         4673 c         3851 g         7044 t
ORIGIN      
        1 aagttatact gaaaatgggt taatactgct tcacatagca gtctcatcgt aaagcataag
       61 taaaaaaggc cagaaatagt gacctcttta tactttataa cagtttatct caaaactaac
      121 taaatatttg taaaacaacg acttgtttta agttaatcat aaacttcttt ttttctaata
      181 ttttgtgcca ctaattgcca ctgtttttca tatatccagt taggatcaga aacaatcgct
      241 gcagaaactt tgcgtgcttc ttctaaaata ggataatcct caacgatatc agctacttga
      301 aattctggaa ttccagactg acgagtacca aagatttcac cagaaccacg catttttaaa
      361 tccgactcag ctaaaacgaa accatctgtc gtttctgtca tgattgtcat tcgttttttc
      421 cccgaatcag ttttgggatt agccactaaa acagcgtatg attgtttata tccacgacca
      481 acacgcccac gaagttgatg taactgactt aatccaaaac gatcggcatc cataataatc
      541 atgatcgttg catttgggac atttacccct acttcaataa ctgttgtgga tactaaaata
      601 tgactttttt tatccttgaa atcttgcatt atagcatctt tttcatcatt tttcatacgt
      661 ccatgtacaa gagcaacctt agcaattcct tcaaaataag tagataattc agcatgcaat
      721 gctactgcat tctttaaatc taaagcttct gattcttcaa tcaacggtga aatgacatac
      781 acttgagcat ctttttgcaa ttcacctttt acccattcca acacagtacc tagctgctcg
      841 tgtttcaccc agcgtgtcat aataggttta cgaccggcag gtaattcatc aataatagaa
      901 acatccattt ctccaaaagc tgtgattgct agagttcggg gaattggggt ggctgtcatc
      961 attaaaacat caggattttc tcccttttca cggaaaattc tacgctgttt aacaccaaaa
     1021 cgatgttgct cgtctgtaat gacaagcccc agtttatggt actgtaccga gtcttggata
     1081 agagcatgag ttcctacaat catatcaacc gagccatttg caatagctgc taaaaccgta
     1141 cgcttgacag ctgctttcat acccgaagtt aatatagcga ttgataaatc tggaaataac
     1201 tcttgcagac taatgtagtg ttgttcagct aggatttccg ttggaaccat caaagccgat
     1261 tgaaaacctg ctgtataagc tgcatacatt gatagaccag caatgactgt ctttcctgat
     1321 cctacatctc cttgcaataa acgattcata tgagctcccg atgacatatc agataatatg
     1381 tcatctaaag agcgcttttg agcatttgtt agaataaagg gtaaagagga aatctttgtc
     1441 tccatagcat gtttactata aagaataggc aaaccatttg tttcagatct attttcggct
     1501 ttcaaaactt gaaggttcat ttgaaagtaa aataattctt caaatttaat ccgacggagc
     1561 gcttgcttat actctgtgat atcttttggg aaatgcatag ctaaacaagc ctgactacga
     1621 cccatcaatc ggtatttttc caataaagta gctggtaaat tttccttcaa ttccaaatgc
     1681 gcatcgattt caaaagctga cttaatagct ttaatcaaag tagactgtga aattccctga
     1741 gctacgcgat aaacaggttg catgtcatct tcaacttgag ctaaaacctt catcccagta
     1801 atagccgatt tagtggcatc ccatttacca aaaacagcta cctcttgacc aagttctatt
     1861 ttatcagcta aatagggttg attaaaaaaa ctaacattta agacagcttc cccttgacgc
     1921 aatttgaaac ttaaacggtt acgtttaaaa ccataatatt gtacattagc tggagtaacg
     1981 actaagcctg taatgactgc tttttcacca tccactaaat caaaaacaga ttttgattta
     2041 aaatcttcat agcgaaacgg ataataaagc agtaaatctt ctactgtata aatatctaat
     2101 ttctgaaatt tttctgctga ttttggtcca aatcccttta agttggacat aggagctgtt
     2161 aatatcatta tctttttccc ttcacaaaaa ctcttgtcag attgaagaca aagtttgtcg
     2221 tgatactttc cttaggtggt gcttacggca gcgacgttct ttggaattcc atgcctttat
     2281 ttttgagcct gaggtctcaa aaatcccgag tggcgtcaat ctcgtattga cgccactctt
     2341 ttaccacagc aaaaagcatc tgttttggct cactttatat gtaaaaatcg gaaaccgaat
     2401 gtcaaatcag cagagctatg catgcttttt gagcataaaa ctggagttgt ctacgttctg
     2461 actcttgtat ctattataca agagttccta tttattttca gataaaagcc ttttagtact
     2521 tttaaacagt tctaggggct cgttaaggta gcatttgata aatggtatcg cagacactac
     2581 ttagaagttc ttcatcatgt gaaatgagga tgacaacctt atgttgggtc ttcagctgca
     2641 tgagaagatt agctaaagcc ttcatttgta acaaatcaag tccgctactt ggctcatcaa
     2701 aaattaagat atctttatca gccaaaagac tagcggcaat catcactctt tgttgctcac
     2761 ctcctgacaa actagctgga tgacgttcta aaagagtcgt taaagataac cgctctatta
     2821 cttctgtcgt ccgtggatgt cgttcatggc ccaagttgac ttcctttgaa accgattctg
     2881 caaatagttg caaagaaact tcttgtaaga caatactagt ctttgataaa cgttgcttgg
     2941 cagataaagg tatgccttga aacttaatag ttgctttttt atcgtctaag ataccagcta
     3001 tataataaac taattgcgat tttccaagcc cgtttgatcc tgtaatgcca gaaatacttc
     3061 ctgcagcaaa actaagctgt tcaatacatc taagtatttt gcttcccgct ctaactgtta
     3121 gatgctcaat acacaggcta tcatctgggc gataatgttg actctcaatc ttaccagcta
     3181 acacaggttt taggtcagac aagtctaagc gacgtagtcc catatcttgc cgttgttcat
     3241 ctgtcaaggc tagcaaatct tgtgttgtta acttatctgt taatctacca tttttaaagt
     3301 agaaaaagtt atctgccaaa tccatcaagt aatgtaagcg atgctcggct acaataatgg
     3361 tttttcctgc tgcttttaat tgggtaagat aggctttaac agcagctatg cctgcactat
     3421 ctaagttagc agttggctca tcaaaaagca taatattagt accttgcata atggccgttg
     3481 caatagcaac tctttgtttt tgccctcctg acaatccaaa catatccttg ttaaggagct
     3541 ctgcaaaagc aaaatcttct gctaaagtcc aaagacgctt catgataacc tttgcatcta
     3601 aaccttgatt ttcacaggga aagaccagtt cgtgttggac ttcgcgatag aaaaactgac
     3661 tggctggatt ttgaaaaaca gaggccacag atctagaaaa tgtttcaaca ctgtctctgt
     3721 ctgcttggca atcagccaca tctagtctac cttcatattt tccagcataa taatcaggaa
     3781 ttatgccatt aagaagtttt aaaaaggtag atttacctga accagaaggt ccacacaaaa
     3841 caatgaattg tccagaggca atttgacaag tcgatacctg acaagctgga tttttttgat
     3901 catgataggt aaaaacaagt tgttctgctg aaatcattgc agtatcgtga tgattatgat
     3961 aacagtaatc caaatctgca ccccccaatc tttccatgtt aagtgtgagc taaagcattc
     4021 actggtgcct ttgttgactg ctagcccttt agttagacta gcgatagtta gttcttggct
     4081 acttcttatc aaagataaaa gcaatggaac cattaaatac tccaagtatt gtttaggtct
     4141 gatcaaaata gaccattttg ttaaaataat ccccctgatt gttaaagagc gatgaataac
     4201 acaacattct tgtctaatca ttggtatgaa acggcacata acggctaagg tcaatagcca
     4261 gacttctggg aaatgccatt tgcgtaatcc atgaaccaat tcgtagatgg tagttgtctt
     4321 aatagtaatt aaacctgcta gtaaagaagg gaaaactaac cttcctgcta ttgagacaaa
     4381 actcaataag tgatcaagat aagaagggaa aatagatagc gggattacag atagaccgat
     4441 cattaacaga taaacaaccg ccaacttgaa tgctagcttt ttcttattta aagcagacaa
     4501 aagtaataag agaaaaataa caattataaa ttctaaaaag ccatcaacac ggaaaaagaa
     4561 gcaggcattg gcaagtacca acaaaagcag tttggtgcga acatcaagcc tcatgataac
     4621 aatcctgatt tgataaaatg tttctttagt aaataatgtg caaaagctga ccctaataag
     4681 gctcctgcaa gaacaattcc tacaaaccaa ataacatgcc ctaaactaaa atcatacata
     4741 atgcgattga cataggtcat acttttaccg cgggctaaca aactttcaac ataggcatct
     4801 ttcaacaacc acatcagcac aatagggcca ctattgacaa aagcaaaaac catataagat
     4861 aggtcattaa aaaaccttga cttgtatttt cctaaagaag caataatatc cgctattaaa
     4921 ccgaaaataa tgctgggaaa catcgcggca aaaaagtgac cactaaggaa gaaaaaacct
     4981 cccatcatca atcctaataa tgttattggc ccaaatgttt gcaatttagc aatcaaaaga
     5041 aaataaattg ttccccccag taaagctgca aaggcagggg catataacat atttcctgag
     5101 cgatcaaaaa agatgttaat aaacgtgcct agaccaacac aaataaagta gagcgcggca
     5161 aatgcgcctg ttatcataat atcttttatt gttaactgtt tcatttttta ttcacctctt
     5221 ttagggaacc attttttacg caaaatagat gatcagcaca agctagggtt gatggcctgt
     5281 gagaaattaa gaagaccaat ccttgacaat gtgttttaat taaatcaagc aagatagctt
     5341 catttagaga atctaaattt gacgtgggtt catcaaaaat atagcaactc gcatctttca
     5401 ataaagctcg catcaactct aaacgttgac cttctccagc tgaaaagtca gaaggactct
     5461 tgataatcgt atccaaacct tccttacaag ctaacagtct gtctttcata ccacaagtct
     5521 cagctaaatt ccaaatggac tcatctgaaa tatcttgacg gccaaaggta agattttcac
     5581 ggatagactg ttggaaaagc tgcgctgttt gtggcacata agcaatagta tcttgtaatt
     5641 tagcagcatt tagtaagcaa ctattcctat cattaagaaa aatatctcct gtcttccaat
     5701 tataccattt cataattaat ttcaccaaag ttgatttacc agatcctgat tcgcctttaa
     5761 tgccaataat ccccttttct tgaaaggtaa ctgataaatc cttaaaaacc agctcttggc
     5821 gctttggata agcaaaactg aggtcctcaa aagaaacact ccttaaacga tctatctgtt
     5881 ttgtgccttc gtctactatg acattttcgt ctagaaggtc aaaaatattt cgagccgcat
     5941 tcatagcacg cttaaagcct aatggcaaac gtcctagttc taaaaaagga gaaaacgaag
     6001 cagtgaaagc aataaaagtt aataagcctt tatcaaatga taagctgtca tggcatatcc
     6061 catcaaaaac catataagaa aatgctaaga tcattaagcc aagccaaaaa aaagtcaatg
     6121 ccatttgcaa aaattgggct tgcgctacgt tacgatcaag agcatttaca tgattacttt
     6181 tttttattaa tcgttcaaat tgctcgtcta atacctgaaa ttgcaaaaga tctttgactg
     6241 atcgtaaact ctctaaaaaa taagacaggt aatcttttcg accttcattt tggcttttta
     6301 gtaaaacctg taaaatatta gcaaaataaa tgggtataac aatggctaaa caagcatagg
     6361 ttgccaaagc taataaggct aactgccaac tactttgaca aaagtaccag aacattaaac
     6421 ctgcagacaa tattgctgta caaataggtg cgattgtgtg ggcaaaaaaa acttctaatg
     6481 cctcaatatc ttctccaatc attttaagca aataaccact gtcttgacta tccaagcaag
     6541 ctggagaaag agctcttagt ttcttaaaga tcaagttcct aaaagctgct aaactatgaa
     6601 aagcaacaaa atgaccaaaa taatgctctc cataacgaac aaaacctctt aaaaaggcta
     6661 gagcaatcaa aagatataaa gctaatattg gaatcacttc ttgtctaata gctagtagtc
     6721 ctaaataagc tattccagtt ggaatactta ccgtgatgac aaaacccata acagcaaagc
     6781 caacagccaa gataatccaa ggtagcagag ttttcattag ggttaataaa cgccaaacca
     6841 ggcttaaggt agatctgtta ggtttagcca taaatacttg cctccagtct tgcttgagta
     6901 tcaactaggt gacgataagt tggttggtcc cgataaaggt cgcaaggttt gcctaaacaa
     6961 gcaggctgcc ctgtgtttaa aaagagtact tggttagctc ctttcagtcg agacatctta
     7021 tgagtaatca caataactat tgctgtctta gctaatctcg ttattaaatt gtcaataata
     7081 cgttcatttt ctgcatctag actagatgtt gcctcatcaa agatataaag agacctctta
     7141 cttaatagag ctcttgcgca aatcacctgt tgcttttggc ctggtgataa caggttacca
     7201 ttttcaccaa ctattgtgtc aagaccatct ggtagccagt tgatgaagct taacaaacca
     7261 tgttgatcta tccaatctaa gatttctttt ttagagagat ttgctgctaa ccttaaatta
     7321 tcgtaaatgc tacggttcaa taaggtagat tggtccgata cataaagaac ctgctggttg
     7381 atagtttctt gcaacaaatt gtcactgtct aaaccgtcaa ataaaatatg cccagtcgtt
     7441 gcagactggc gtttcaagag gagttgagct agacttgttt ttccttgtcc tgacaccccc
     7501 gcgatagctg ttagttggcc cttcgttaat gtcatggtaa ccccactaag cactgttttt
     7561 ttctcataag ctaaagaaat attttggatg tcaatctggt taaagtttat tgctgtttta
     7621 ctcttgttat ctttccttgc tggaacacta tccaagaaac taaagatacg gtcagccatt
     7681 ttggtattca tcatgaccaa gtgcatgcca taaccctgct cacgaatcgg tgtaaaaaat
     7741 tctgtagcaa tcaagagaaa aaagaggaaa ttaaaaaagg ataactggcc tgttgccaaa
     7801 gcttgaacgg ctaaaaaacc tgacaaacca attcccagat acataactgc atccatataa
     7861 ccaactgctt gtaactgaaa gccaagcaaa gacatggtag cctttcgaaa ctgttctgcc
     7921 ttacccgaaa attcttgctc gtaacgttct attgcttgat aagaatacag tgtattaaga
     7981 ccttttaagt catccataaa taaattacca acatccatat aagaagacca ataatgactc
     8041 ataatttgct tagaccgctt ttgcatagca acgattgaaa gtggaatcag aagcagaact
     8101 cctaaaaaga caaggcctgc caatggataa attaaaaaaa ctagtatcat aatagttgtg
     8161 cagttccact tggttctcat agacaaagac aaatagtaac cataataagt atccaaacta
     8221 tcaatcccct gtgaagccaa cgttaaaata tcagcatcac tggcatgagc atcaaattgc
     8281 ccgtctaaat caataaaagc ctcaaagaaa gattgtttga gtgaatctct agcaaattgt
     8341 gaagcgatcc cttgcagttg cttgcctaat atagcaagaa caaagcctac cacatttaaa
     8401 agtaggagta aacctgccaa gcgtcctaag gcaatagcat gacccaaaat aaaggtcgaa
     8461 aacgttttgg caatgaggta aaaactgatc atcctcatca caaattgtaa ccaagataaa
     8521 aaggctgaca cataaagcaa ataccttttt ggtgcaattc gttcacgtaa tcgttttaac
     8581 agtcttttcc tttttcccct tgatattgta tcttctgttt ccatcatctg ttcttgttcc
     8641 tatctctcct ttgagttcta atatcattgg tttcattgac caatgaagtg aggacaaact
     8701 gttgaccatt tctctcaaca aagggcaatt caacaccaaa gacatctctg ataaactgtt
     8761 gatcaaggag gtctcttggt tgcccttggg cataaagtcg cccatctttc agtccaataa
     8821 gatggtctga aagagacaag gcctgattga tgtcatgtaa tactaacaca atcgttaggc
     8881 ctagctcttg gttgatttta gtaatcagct tgagaatgtc aagctggtac ttaatatcca
     8941 aataagtcgt tggctcatct aaaaaaataa tatctgtatc ctgggcaagg gccatggcaa
     9001 tccaaaccct ctgctgttca ccaccagaaa ggtgttggag gtcacgataa acataatcac
     9061 tcaaagccgt tacttctaag gcccaagcaa ggcgttcctc atcttctttg gtagtagttt
     9121 taaaaaaaga acgacgggca agcctagcca tggctaccaa ttcacccact aacaaacctt
     9181 cgaccacttg atggtattgg tgtaccactg ccactttttt cgcaaaagcc ttgagagaaa
     9241 tcgttgctaa ttcttcctgc tcaagccaaa cctgcccttg ttttaacgga aggtttttgg
     9301 ttaataattg taataaggtt gacttgccac tgccatttgc ccccataata gtggtaattt
     9361 tcccttttgg aatgctaaag gtcaggtcat ctaaaacaag tttttcctca taagcaaagg
     9421 aaaggttttg cacctgaata tgactgctgt tcttactcat ataatatcag acctccttag
     9481 caggtaaata aagtaaggcc cgcctacaat actcattata atcgcagggc taatttccaa
     9541 tgggtaagca agacttcttc ctaaagtatc ggctagcaaa aagacaaagg ctccaagcaa
     9601 agctgaaaaa ggaattaaga tttggtgctt acttccaacc agcaagcggc tcatatgagg
     9661 gacaatcaag cctaggaaag aaaccactcc aacgatcgaa gtggctaccg aagccaataa
     9721 aacagcaacc aaggaaattc ccaaccgtaa cgctgtagca tcgattccta aatgacgaat
     9781 cacctgatca tctaaaagaa gaaggttaca ggtttttgac aataacaaag ctagtaacaa
     9841 gccaatgaat gtataaggga ataaaacccc tacatcagcc catgtttttt gactaatatg
     9901 acctgctaaa agagcattga ccatgggact agctgaggtg aaaaagctgg ttaaagcagt
     9961 tgataacccc ataaataaag cattaatagc aatccctgtt agaataagcc gaataggatt
    10021 aagccccttc ttccatgcta aaccataaat cagcaggaaa gacactccgc ctcctaaaaa
    10081 ggatacgatt ggaccataca gcagcaactg cggtagaagt aaactagaga ctaaaaccat
    10141 aaaactagca ccactacaaa tccctataat agcagggtct gaaataggat ttttcaacac
    10201 tgcttgaaaa agaactcccg aaaccgctat ccctgctcct gctaataaag caatgacaat
    10261 tcttggaaag cgcaaatcat aaatcaaagc cacttggggg tcataagcca caaacagtcc
    10321 cttgacaatt gccccataag aaaccgccaa accaccaagg gataaggcaa taaccgccaa
    10381 aaacaggaga ctgagaatta aaagaactag ataaagacca cttctgaaac gttttttagc
    10441 cagtagggat tgatcccttt gtaaatctga tgctgtcatg ttacgaatga tctcccacgt
    10501 ggtcaaaaag ctgtgttaag gtgtccaagg cttctgggta gttcaattta gcactcatgc
    10561 caaacagggt attgtccaaa tcatagactt tcccttcctt gactgccgta aaatgtttcc
    10621 aaatatcatt ttcagcaaat tctttgtcaa acatcacttt taccttgtct ggaatggcat
    10681 gagctgttcg taaaatcaag tcaggctcct tagccagcat gtcttcagga ttagctgata
    10741 gaaattcttt ctcatctgac tgataaacat tctcaccacc tgccaagtcc aaaagattcc
    10801 ctacataaga ttggtttgtc gccaccaaat aactacctgg caagcccata agaataagca
    10861 ctttaggctt tttcttcccc ttacgtttag cttggaaagc acgataatag tcctggtatt
    10921 gctggcgcaa ttcttttgct tcttgttgac gttggaaaag gttccctaaa tcatcaatgg
    10981 actggtacat gccctcaaca ctccgtaagt tcaaaaaacc atactcagta tccaattttt
    11041 gatacttggg ttccaaatct tcttgtaaag aattgggact caaaatccaa gttggtttca
    11101 aagaagcaat caactctata tcaggattca tgggtaaacc cacacgctta acagcatcat
    11161 agcgtttagg aagggtatat aatttactat cacaaacccc aacgaggtct aaatttaaac
    11221 ggtcacagat gtcaaccaca gcaaccgaag tggctacaat tctctgctgt tcagactctt
    11281 tagccgtttt atggtgctga ttcacacaag ctaccaaaaa gaaggccatt aaggctagac
    11341 caattccttt acatcgtttt atcatttttt ttcctctttt tccaaaccca tacagcaaac
    11401 cctcctaaca tcagaaaaaa agttggaaag tagtaaatca tgattgataa gtctttttta
    11461 gaccgaaact tatcttcttt ttttaactct aaagaagtcg ttaagcccat cttagaagga
    11521 agaatttttt tatctgatag actcttgtta tttgatgagt tggctttagg cttattctga
    11581 gttatcatag cacctgtgtg agactcatct tgactttctc ctagttttgt atcaacaggc
    11641 ttttgattgt cttttacttc ttgattttga gaattgtctg tttcagtaac aagctgggcc
    11701 aacatattac ctgaatactt ttgtattaac tctgaagctg acaggtaaaa gaccacttct
    11761 ctgcccatag gttcaacaaa catgcttcct cgaatgatac tatttacagt aggcaaacta
    11821 atagcaatat ctagtgttgt cccattggta tcagtacctt tttgggtgat attgtaatca
    11881 actgcctgaa agcttccagt tcctccaggt tgtatccaga actgataatt gcccgaataa
    11941 tcagctaagc tcatacgaaa agtaagaacg atctttccag catcagatac ttctagcatg
    12001 gcatcactat agacagtccc ttcaaccata ccttgaccaa tatcaaagga atgctcacct
    12061 ccgctatctt ctatctgccc agatatcgga tgacgataat ttctctgaat aatacatcca
    12121 taaatttgac ctttatctgc atacacaaca cctgtcattg tcgataaact tatcatgaac
    12181 actactatta cctgcaacaa ttgctttatt actacctttg tcatatgctc ctcttgtcta
    12241 tcttttctta aacatcttat ttcatttttt aaatgattcc cattttataa catctccaaa
    12301 tgtgaaaaac acacctatct tgcgactact tcaacctgta tcaggagtcc tgtcggaaat
    12361 aggtatgttt ttagctcttg ctgactagct tttttgttat ttcacttggt actaagtttc
    12421 ttatttaaat aatgtctttc gaccaataat gaatcccaga gctacgatca taaagctaga
    12481 tagacctgca attaagtgat aacgagagct actttcttca ccatttgatt gttgattgga
    12541 acgatgtttc ttatcagatt ttttagtctt agtatctttt gccgttttac cttcaattga
    12601 tgtttgatgg tcacgcacta actgtttcaa tttctctgcc ttatcagtat catctgtctt
    12661 agaagtttct tgagttgatt ggccggttgc ttttttagcc aggagatcag ttaagttagc
    12721 aataccagta gctgctgaag gaggacttgt aggtgttttt tcttgttgac gattttgagg
    12781 tcctttcaac tgatctgttg aagttagatg gctattttct tgtggattat tagtttcttt
    12841 gacaaccttt gccttctctg tcgtaaggct tgcccagtct aaacgcataa aaacggtttg
    12901 aaggccagac ccttttgaaa tggcatccat gataggcaca aagacctgta atggcacaag
    12961 tccgtctttc ttcgcttgtt caatcaattt catacgcagc acttttggat agttttttcc
    13021 ataacgatct gccaatggta ggccagttac atccgtgaaa taagacacaa cctctgcctt
    13081 ttttgttcga ccaactggtt taccagctaa atctctttgg taaccatcta cgaaatagct
    13141 caattcacca aggtagccta acattttacc aacctttatc cctctaaact caacttctaa
    13201 ataggaaaca ccttttttaa ctaccaaagt cactcgatga ttaatagcct tgtttgacat
    13261 ggactcagat gctaagtcag tttttaacat gctggcattt aaatagtaaa taccatcacg
    13321 caattgtttt tgatttaatg ctctaaggcc tttctcaact aaatcttttt gatgtgaatg
    13381 tggtcctttc gccacaagga tatcattaga tgtcaaatag atatgttctt tttgagtagc
    13441 aaatttcttt gttattaaag ctttgcgaat ccgatatgta cctggatctt ttaaagaaaa
    13501 ctctcccgtt aagtcatctt tcggatcatt tgagagaagc ttttcgtcaa ccgtcacata
    13561 ctgtccgttg gaagcttttt tttgcaactg aatcacaata ctccaatcga cttgcatatc
    13621 attaagtaaa gagacagtat ctgaaccttt ttcttgtaac aattgttgat attcttcaat
    13681 agacactagt tctttatcaa tggcagaatt tgttttttgc tcccaataat acaaatctaa
    13741 aagactgaaa gcttgatgat attttatttt ttcgccatct aaggaagctt caagttttgc
    13801 aatatgtttt tgtggagtca gtttgtgttg tccgataaga gctcttactt ttggactcac
    13861 actttttatc tgattgaact tcacatctaa attaagcgtt tcaacatctg gaaatactga
    13921 ttcttcaacc tgagtaagca agttattgaa aaaatcaagt tttgttaatt ggttattctg
    13981 tttaaatata ccatttggaa gatttgaaat ttcattagtt gataaatcga gtacagataa
    14041 tttaggaaga tttttaaatg aaatattatc aatacgagta atatgatttc tacttgccac
    14101 aatagtgctt aaggcgcgca atttttctat tgtttttggc agtagtgcta aattattttg
    14161 agataagtcg ataaagttaa gtgatgttag aggctctagc gctttttcag gtatctcctc
    14221 aagactattt tctgcgaaac ctaatgaagt caggcgagac aatccttcaa atgggttatc
    14281 acaaagtcgg ccaatacgat tcttggaaag atcaagttgc tccaggtgat gaagcgactg
    14341 gaatagtcct ccttcaagag agtgaataaa gttacttgat aagtagagtt ctcttaattg
    14401 agcgttgctt ttaaatgtat ctttgtctag ataagttaaa tgattacttc ttaagttaag
    14461 aaatcgaagt tgcttcattt gactaaataa ctcttttgga atttccgtaa tttggtttcc
    14521 atccagatgt agttctgtaa tatttttagc atgtttcaat aaagaaatat cagttaactc
    14581 gtaatggtct agacgcaact cgcctcgaat ctgttctaat tccgtttttg ataatttacc
    14641 atcgccgtct aaatctttgc caagtttaac taaaactttt tcaagacgtt cagtcccaac
    14701 ccctttttct ttatcatcag tttctacctg ataaccactc cagcctttgg taacggtctt
    14761 actaaaggtc atgtcaagtt tggtgtattt gtcatagtgg tttaaatcac tttcttgacc
    14821 tcccatggct gataccaaaa cagcaccttt gtgtaattta tccaaatcat caataggcat
    14881 ggtaaattcg cttcgaatat agctaccatt gatatctttt tggccaactt gtttacgcac
    14941 tgctgctggg taggtccctt tgctttcaat agaaaagtca atcaaaaatt gtcctaaagc
    15001 agtattaagc atggaaattt ccattgtacc atctgcttta accactaatt tggctctttt
    15061 atcaaaagca ccttgaagca tggaggactc ttctgagttt tctttattag ctttaaagtt
    15121 tagcgtatag gttccttctg tgagattgtt aatagaaacc tcacctgctt gataagactc
    15181 gatggtatct tttaacagtc gatgagtatc ggcgagtagc ttactatctt tgatttcttt
    15241 gtaagaatcc ttgatgactt gaagtttctc agccagatct ttgaccgcgt ctttgttgct
    15301 ttctttagca ataatcgcat ccgcttcttt gatagctttt ttcaaagtgg tgacatccaa
    15361 ctttgttgat tgtctgtctt cagcagtcac atgttgtttt tgtttggcag atacaaaatg
    15421 gatttgacca tctttcttgg taacggtaat ggtaacgtct tcaaatcctt ttgaggatat
    15481 cacgattgta ttttctccat ctttgaaagc ttttgttcca agatgaagcc ctgtcatatt
    15541 cgagacccag ccattagtat cttttacaga atctgaaata agatctttat aaactgtacc
    15601 attgactgta acctttgtga tttgctgagt caatgctttt atctgtttgt tatcagaata
    15661 acgatcaatt tctggaaata aaattgcacc atcttcttga ctcaattttg ttattaatga
    15721 caagttagca gtatttttcc cagatttaac aactttttgt gtgccttggt tttgtggcac
    15781 tgttttatca ctgagcacat ctttttttaa tgaatcctga tgatctgttg ttcctaattt
    15841 ttgagctgaa ataaaggtca ctttatcgcc ctttttaata aaggtaatta ggatatcacc
    15901 atctttttta ttaacaatag tcaattcatg cttaccgtct ttaataaggt tagcattgat
    15961 cttaatccct tggtagttaa tatcaaaggt tcgctcgcct tccaggcttt tttcatagac
    16021 atcattatca acaataacct tttcaatatg tttataatac tcttttccag ctgattgact
    16081 agcgtaaggg cctatctctt caactaaaag tcgattatcc tgagttaaag ctactgttgt
    16141 cacgagttgt gactgaacta aaggctcttg tgattttaca gtttgagtag cctgaatgag
    16201 aacaagggca gatattgcca caaacgcaca tttgctgatt tttttcattt tcaatcaact
    16261 ttctaaaaat ttttatgaat aagctaactt ttttattaac tgaacttaat ctatcacttt
    16321 gtgattattt tgtcaagatt gtttccaatg gtccaattgt ctgttaaaaa gctccactat
    16381 gtgagccaag acactagcaa taagcctgga ttgataatga tgatatctct gataaaagaa
    16441 ttcctctaca acaatattac tgagataaag ctagccttag gatagttatt actagggctg
    16501 attcaatcat tacttcattc acaaaacatg taacacgtta taagctccat aattgtgtta
    16561 ggagacaaca tgagatgtca ctactgcata ttcatcacaa taaaaaaaga caatagccct
    16621 aatcgtgcta ttgtctcaaa atcatttatt tacttgaaac tttatcgtgt tacaccaaca
    16681 gtttaaaagg cctaactccc gctaagaaaa ttaagcctta agaaaagtca ttagttatta
    16741 gtttttactc ttgccaataa catatgttag ctgttcagcc tgctgagctg taaaggtacg
    16801 ataagaaatc ttacctaagc cgatacagtt agactctgaa ataagaatag acccatcttt
    16861 tctaacatct tctacaattg atacgtggcc ataagtgcca tcagcgcctg cttgccctgg
    16921 tgcaaatgaa atagcataac ctacttttgg agtctttgac agggcatacc ctgctttata
    16981 cttccaatct ccaccatttc ccataaaagg atcaaattgg taacccaatt ctttggcgcg
    17041 attatacaca taccaagtgc attgtcccca agcataactc gaagcttgat aacccaagac
    17101 atcataactc ttagagagct tataacctgc tggcacagat gcaaaactag ctgatgactg
    17161 cactttcaat tcggctggaa tggctggtgt gccaccatgg tcatcaatcc acttatccag
    17221 gtcttccata atttgtgcgc gacgtttacc actaccagta gtatcagtaa aataaacacc
    17281 cccgtcactt gcaaagttta attgacctcg tgaaaactta gccgctttta aatcttgaag
    17341 tgcaaaattg ctatttttgt ttttaataat ggtatcttgt gtcattttga caatagcact
    17401 atcatcatta aacttacttg cttgagtcgg atctagatca aaagctgcat agccaaacat
    17461 attagctcca agcaaagtcg caatcccttg agttcctaaa gaactctcag acatcgcaat
    17521 agctacgata gctcgaacat ccagcccact tttcttttcc cattgcaata gcttctcacc
    17581 attaatacgt gtgctgtcat aggcaatgcc tgttgatttt aagtaactat caatctggtc
    17641 agctttaata ccataacggc gagataaaag atgatgggta taggcatttt taccactcca
    17701 atgctctaca tatgccgcgt atgtgttgac agaagggata tctatctcac tcaaatctaa
    17761 atctgatacg taaggggaca acgactgaat aggagttctt gcctctggca gctgtctcga
    17821 caatgaagaa gcaggtgccg tatcaacttt agatggtgat ggtttgggct gatcagtcgg
    17881 ttttggctgg tcagttggtt tcgaatgatc agttgattta tcatctacct ggttttctgc
    17941 ttctgccttg ttgttcgaag agcctacagc agactgacta gaatcgcttc tttttttatc
    18001 atccgcgtta acaagactat tagagtttgt ttctgcagaa gcatcaaggg gaccttggtc
    18061 agttttatct gatgttgtag gtgctgcatt tttattattt tcctcttttg aagaagaatc
    18121 actggtttca tttgtagttg ctttatgcgt ctcaagcatt acatcttgag ccaacactgt
    18181 catgctttct gctgtcgggg ctaagagact tagtagcatg gcaactctta atagtttgtt
    18241 tttattcata tattaattag tcacttcttt ctaatgtcct cactttatta taacattaaa
    18301 gataagcaca atgcaattat ttttacgtga ttttcttaat atatccgagg aatacggtca
    18361 cttaaaaggc atagaacttc ataattgatt gtattacggt aatttgcgat atctgttgta
    18421 gaaatatttt tttgctgatt gctgccaatc aaagtgactt ttgttcctaa aggatatgct
    18481 ttgggaagtc gtatggtcag ttgatccatc gatacacgcc ctataatttc acagaattgt
    18541 ccatcaacta acaccgaaaa gccttgcatg ttcctggtcc agccatctgc ataaccgatt
    18601 gggacggtcc ctacatattc agactttttg gcagtataag tagctccata accgactgta
    18661 tcaccagctg aaatcatctt gacatgcact aagctagatt ctagagataa agcctcttgc
    18721 agtggaaatg gtaagcttag atcagaacca cttggattca aaccataact aacaattcct
    18781 aaacgaacag cattaaaaat ggtatcacta tgccagatac ttgtggctga attactagca
    18841 tgtactaaac gaggcttatc ctcaagtcca gctatcagct ttttaaaaaa ctgtaactgc
    18901 tggttaaatt tagtatcatc tgcctcatca gctgtggcaa aatgagtgaa aataccttct
    18961 acatcagcac ccaactcttt tagactatca atcaataaat tgactgcttt tgaagaacga
    19021 agcccgatcc gccccatacc agaatcaact tttacatgaa cttttaagcc ttgacattct
    19081 tttttctcca gtctagctaa agctatccag tctaaactag cgattgtaac agtaatagca
    19141 ttagcaactg ctaactctaa ttcatttggc aggaggactc caagaattaa aatctcttta
    19201 tcaatgcctg cttgacgtaa ttgcaaagcc tcatcaagat ttgacacaca gtacccatcc
    19261 acttgaggta ggagtgcttt tgacacctgg acagcaccat gaccataagc atcagccttg
    19321 acaactgcat acgtttttac ccctagtgga atatgctttt gaacactggc aacattctcc
    19381 ttaatagctt gtaagttgac ccttgcaact gttgggcgat ggaaacttga aatcattttt
    19441 tatcctccaa aataacacta gcctgtacat aattgccact atgtgagatg ctaataaaac
    19501 tatttccttt aaacggagat tttgtcagaa tgggacatcc tctaacatca tttaaaatct
    19561 caatatcttg aaaggttaac cgcccaatac ctgtccctat agccttagca aaagcctctt
    19621 tgcctgccca acgacccgcc aaatagctga gtcgacgttt ataaggaaaa ctctcaaaaa
    19681 tagccaattc ctgctcagtt aaaatttttt gagcaaagcg aggatttctt tgataaactt
    19741 tttcaatagc tgaaatctct tgtaagtcta ttccatgtcc aacaatcatt actttccacc
    19801 aaaccttatt tcatcttaat gttagaagat ttaaacagtg agaagctgag aattattctc
    19861 agcttctttc tatataccta actttgtcct gttgtgtctc gttcttatga gaaggattta
    19921 cgaccgtgac aatttttgaa ttttttgcct gaaccacatg gacaagcttc gttacgctcc
    19981 actttgggta aatcatcggt gttagctgac tgctgcgatt ggatgttttg aggtgctgct
    20041 gttgtggcac gttgacttgc acgttcacgt tcttgttcgt gaatttgtgc tttcatcatg
    20101 gtacgtgtta catcaaactc gatagcacca atcatatctt ggaacatctt gaaaccttct
    20161 gcttggtatt ccaccacagg gttattttga gcataccccc gaagtccaac agcattacga
    20221 agttgatcta aggcatcaat gtgttcagtc catttgttat ccacaatcat caaaatgagt
    20281 actttttgga attcaataat agcttcttga tcacgaagtt ttgatagttg ctggtcgtag
    20341 atagcaagcg ctctttgata aagcttctct ttgatttgat catcttttaa accacgtaac
    20401 tctttagcac taatagactc ttctggtacc agcgaggtcc tagcaaaagt tacaatagca
    20461 tctatagcat ctttacgatt gctacgtgca tgagcatcta cagcacggtc gatagtacgc
    20521 ttgatcatag ctttaatttc tgggccaaga tctcgattag cagttatgac atcacgacgg
    20581 ttagcataga taatttcacg ctgttcacgc atcacatcat catattgtaa gacctgttta
    20641 cgggtatcgt agttatttcc ttcaacccgt ttttgagcag attccacttg acgccctaac
    20701 atacctgatt taataacagt gtcttcttca tctaatttca tccgatccaa aaaggctttt
    20761 atacgatcag agccgaaacg tctcatcaaa tcatcttcta atgaaagata gaattgggat
    20821 tcacctggat ctccttgacg acctgaacgt ccacgaagct ggttatcgat acgacggctt
    20881 tcatgacgct ctgtaccaat gacacataac ccaccaagtt cacgaacacc ttcaccaagc
    20941 ttgatatcag taccacgacc agccatgtta gttgcgattg taacagcacc acgttgccca
    21001 gcattcataa tgatttgagc ttctttaaag tgatttttag cattcaaaac ctcatgagga
    21061 atccctgctt caaccagctt gcgtgaaatc aaatcactag tttcaacagc aaccgtacct
    21121 acaaggatag gttgtccttt tgcatgacgc gttttaacgt cttccacaac tgctctaaac
    21181 tttgattcta aggtcgggta aagcaaatca gtgtgatcaa tacgggcaat tggacgattg
    21241 gttggaattg gaataatacg catgttataa acttcgcgaa attcttcttc ctcggtcttc
    21301 gcagtaccag tcatacctgc caattttttg tacatacgaa acatattttg gtaggtgatt
    21361 gaggcgctgg tttttgattc ttcctgaata cgaacgcctt cttttgcctc aatagcttgg
    21421 tgcaagccgt ctgagaagcg acgcccttcc atcgtacgac ctgtaaattg gtcaacaata
    21481 agaatctcac catcctcgct gaccacataa tcgatatcta acaacataat atagtttgca
    21541 cgaagggcgt tgtctataaa gtgagtcaag gctacatttt caatatcgta aagattgctc
    21601 aagttaaaat aactctcagc tttatcaata cctgaatcgc ttaatccaat cgttttagtg
    21661 ggcacatcaa taacataatc cactgacgtc agagttttta caaacatgtc agcacgaata
    21721 tacaattgat tggtttcaga gctaacagca ccagagacaa ttaaaggtgt ccttgcctcg
    21781 tcaattaaga ctgagtccac ttcatcaacc aaggcaaaat tgagtgggcg ttgtaccatg
    21841 tcttcctggc gaacaaccat gttgtcacga aggtaatcaa aaccgacttc agagttggtt
    21901 gaataagtaa tatcacaatt ataagcttca cgtttttcag caggagactt agcagctagg
    21961 ttgatcccaa ctgaaagacc taaccagcta tacacttcac ccatttcggt agcgtcacgc
    22021 gttgaaagat actcattaac agtaataacg tgaacaccct caccagcaat agcattgaga
    22081 taaactggca tggtggctgt aagagttttt ccttcaccag tacgcatttc agggacatcc
    22141 ccgttatgaa gaacaattcc tcccataatt tgaacacgat aagggaacaa gcccaacaca
    22201 cgttttgctg cttcacgaac aactgcgaaa gcctcaggta atagttgttc gagggtctca
    22261 cctttttgat agcgttcttt aaattcaagt gtttttcctt gtagatctct atccgacaat
    22321 gacaccattt ggtctgcgta ggattctact ttttttgcaa ttttttctaa ttttcttagt
    22381 tcgcctttgt cattttcgat aactttgcgt agaatattgg ccattctctt tcctttcgat
    22441 catctaatca tttcatttta acataaatat gtaggcagtt caagaaaggt tggtaaagtt
    22501 a
//
LOCUS       DATWVB010000026        21603 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.026, whole genome shotgun sequence.
ACCESSION   DATWVB010000026 DATWVB010000000
VERSION     DATWVB010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21603
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.026"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            79..333
                     /locus_tag="VCX65_001155"
     CDS             79..333
                     /locus_tag="VCX65_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEP5053619.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            354..749
                     /locus_tag="VCX65_001156"
     CDS             354..749
                     /locus_tag="VCX65_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEP5053620.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            1035..1354
                     /locus_tag="VCX65_001157"
                     /pseudo
     CDS             1035..1354
                     /locus_tag="VCX65_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351072.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            1351..1914
                     /locus_tag="VCX65_001158"
     CDS             1351..1914
                     /locus_tag="VCX65_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEP5053621.1"
                     /translation="MNLIIIGAQASGKMTIEQEVARQTGMNLFHNHDSIDFVLRFMPW
                     SQESTALIERMRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     FVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHY
                     QKINNTHLTAAETAQLIIQKMTHIKEN"
     gene            1916..4564
                     /locus_tag="VCX65_001159"
     CDS             1916..4564
                     /locus_tag="VCX65_001159"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEP5053622.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDNRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIV
                     RLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVERLKDLIRAVRNAR
                     AEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVIQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            4718..7126
                     /locus_tag="VCX65_001160"
     CDS             4718..7126
                     /locus_tag="VCX65_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HEP5053623.1"
                     /translation="MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFL
                     IGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
                     EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKK
                     LCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDT
                     VNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKR
                     DSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTG
                     DLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANL
                     RRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEID
                     HRICYGGNLGELAEIVELTIEEKQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVL
                     AIFNTKKTVHNCYTMLKDITDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICIST
                     QLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLT
                     EIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLN
                     IYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVPYGEAEKKLAYLEELGMSHFLS
                     AEDYQTIKSLLKELQPFTVNVRENDPLFETTKSYLNGQILVLTSEYYDTERGVKYDSA
                     SFYF"
     gene            7259..7987
                     /gene="cas5c"
                     /locus_tag="VCX65_001161"
     CDS             7259..7987
                     /gene="cas5c"
                     /locus_tag="VCX65_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEP5053624.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            7987..9882
                     /gene="cas8c"
                     /locus_tag="VCX65_001162"
     CDS             7987..9882
                     /gene="cas8c"
                     /locus_tag="VCX65_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEP5053625.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQNNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKTLHQSYISFVEANREKLGI
                     CNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLENKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSEFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            9887..10735
                     /gene="cas7c"
                     /locus_tag="VCX65_001163"
     CDS             9887..10735
                     /gene="cas7c"
                     /locus_tag="VCX65_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEP5053626.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKSIFVQANERIEDDFRSLERRFSQHFTAKTPDKEIEEKANALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYHQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTV
                     EILEGL"
     gene            10737..11411
                     /gene="cas4"
                     /locus_tag="VCX65_001164"
     CDS             10737..11411
                     /gene="cas4"
                     /locus_tag="VCX65_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEP5053627.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQV
                     LHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMQEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            11408..12433
                     /gene="cas1c"
                     /locus_tag="VCX65_001165"
     CDS             11408..12433
                     /gene="cas1c"
                     /locus_tag="VCX65_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEP5053628.1"
                     /translation="MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGI
                     VCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREE
                     SLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGCASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVK
                     ENGSILMTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLE
                     SYPPFMV"
     gene            12444..12737
                     /gene="cas2"
                     /locus_tag="VCX65_001166"
     CDS             12444..12737
                     /gene="cas2"
                     /locus_tag="VCX65_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEP5053629.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   12885..13047
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=12886..12916
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaa"
     gene            13208..13918
                     /gene="ccdA2"
                     /locus_tag="VCX65_001167"
     CDS             13208..13918
                     /gene="ccdA2"
                     /locus_tag="VCX65_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEP5053630.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHIFLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            13931..14554
                     /locus_tag="VCX65_001168"
     CDS             13931..14554
                     /locus_tag="VCX65_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEP5053631.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMVKKEITQDKMSMAVKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFTKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            14597..15703
                     /gene="msrB"
                     /locus_tag="VCX65_001169"
     CDS             14597..15703
                     /gene="msrB"
                     /locus_tag="VCX65_001169"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEP5053632.1"
                     /translation="MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKVDPNAPVDQKVIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVTYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE"
     gene            15791..16531
                     /locus_tag="VCX65_001170"
     CDS             15791..16531
                     /locus_tag="VCX65_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEP5053633.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLQQKLDLSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKDLGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            16528..18261
                     /locus_tag="VCX65_001171"
     CDS             16528..18261
                     /locus_tag="VCX65_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP5053634.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQAMPVLTPARQLSLSS
                     KKEWVVSVTQEVVDRAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTNLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGK
                     GIEDSSLTNSQSLLARGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLTLPKMH
                     ELMADDTQENE"
     gene            18334..19413
                     /locus_tag="VCX65_001172"
     CDS             18334..19413
                     /locus_tag="VCX65_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEP5053635.1"
                     /translation="MSLASDYFSRQTPIVEKLMAYGFEKRNNGYFYNERFMEEEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVEGKWYAMIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKAFPQLLQQEGIYPAYHMSKKNWISIILDDKVTDDKLWTLVTQ
                     SRQLVNPNGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYI
                     TAPVKSIRYVCQVLETNIPNEGYRKNPNIDKLMRLRKRQQYKDGLLSFDLMKKHGVAA
                     VRGPRRLSPQLIAFLKEKEYFKENN"
     gene            19427..20143
                     /locus_tag="VCX65_001173"
     CDS             19427..20143
                     /locus_tag="VCX65_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEP5053636.1"
                     /translation="MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALDFIEGSAKMYLHA
                     ITSVHVLDKDNPHVPLFTEN"
     gene            complement(20309..20782)
                     /locus_tag="VCX65_001174"
     CDS             complement(20309..20782)
                     /locus_tag="VCX65_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEP5053637.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATICGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            20924..>21603
                     /locus_tag="VCX65_001175"
     CDS             20924..>21603
                     /locus_tag="VCX65_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEP5053638.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDK
                     DYFLQYTK"
BASE COUNT         6782 a         3854 c         4691 g         6276 t
ORIGIN      
        1 cagttattaa taacatggca caagaggcct gccttatggt ataatggtaa agatgatttc
       61 agaaagagga agctaagcat gtcttatgaa aaagaatttt taaaagattt tgaagactgg
      121 gttaaaactc agattcaagt caatcagcta gccatggcaa ccagtcaaga agttgcccaa
      181 gaagatggcg atgaaagggc taaagatgcc tttattcgtt atgaaagtaa gttagacgcc
      241 tacgaatttt tactaggtaa atttgacaat tataaaaatg gtaaagcctt tcacgatatt
      301 ccagatgagt tatttggagc aaggcattat taaggacaag gagacacgaa atagtggcaa
      361 aacaaaaaaa tcgtaaaaaa gcattgaagt tagaaatgaa gcgtaatggc ttgttaaaaa
      421 aagcaggtca agtttttgat aaggcagttg aaagtgttga aacagccgtg gataaaacca
      481 tttctgctgg taaaaatctt gtggaaaaag gcagccaaac ggttgaaaac ctgacagcaa
      541 gcaaggaaag acttactctt gatgagtttg cagggcagcc agttgtagct ggtatccgct
      601 ctgaccttgt cgaaacccta tatgcagaag gcatccattc agcgcaagct tttaaggagt
      661 ggacagaaaa agacctcctt gctcttaagg gcattggccc agcaacggtt aaaaaattgg
      721 tcgaaaatgg cgcaagcttt aaaaaatagt catcttctcg ttgcttaatg gctataaatt
      781 tgttagaata ttagcaatca gaggtgcatt gagttggtct gttacagaga gcggtggtgt
      841 tgagaaatcc gcacagatgt caaggctggt agctgaggat aagaaatcag atatgaaaag
      901 tagcagatcc attttatggt ctgaaacagt ggtggtaccg cggaaatcgt aacacgaaat
      961 tcgtccctgt ccagtgtaag ctggataggg attatttggt ttcatttgaa agaagatgat
     1021 ggcttattgt taaaatgttg ttagaagtat acaatagaaa aactttgccc aaagtggaaa
     1081 cagaacggct gctattacgt caacgaaaag gggacaaggc attattccag aagcggcttc
     1141 agctctgatt gaaattggtt ttaccttact tgatttgcat aaaattgagc tgggttgcta
     1201 cgactacaac aagcaaagtc aggcagtggc tcgcaaatta ggctttacct tagaagccaa
     1261 tgtccgtgag cgtaaggacg ttcaaggtcg ccgctgtggc ggcatgcgtt ttgggttact
     1321 gagaagtgag tgggaggagc agaaacaaaa atgaacctta tcatcattgg tgctcaagcg
     1381 tcgggcaaga tgaccattga gcaagaagtt gccaggcaga caggcatgaa tttgtttcat
     1441 aatcacgatt ctattgattt tgttttacgg tttatgcctt ggtctcaaga gagcactgcc
     1501 ttgattgaac gtatgcgttt tgcttttttt gaaacctttg ctaagacagg tcaagacatg
     1561 atttttacta ttgtaattga cttcaatgat ccaaatgatg tagcaatgct tgaaaagatt
     1621 caggctgttt ttcagtctta tgaccaagag gttctctttg tcgaattaaa aacagatata
     1681 gaggaacgtc ttaaacgcaa tcgcacagaa aatcgtctca aacataaacc tcttaaacgc
     1741 aacatcgagt ggtcagaaca agatattcaa tccacgatgg catatgctgt ttttaatcca
     1801 gaagaaccac ccaaaacgct cacgcattac caaaaaatca ataataccca tctcaccgct
     1861 gctgaaacag cgcagcttat tatccaaaaa atgactcata tcaaggagaa ctaagatgac
     1921 agaactatca cctaaataca atcctgccga ggttgaggca ggtcgctatc aaaaatggct
     1981 tgatgcagat gtttttaagc catcaggaga ccaaaaagca aaaccgtatt ctatcgtgat
     2041 tccaccgcca aatgtgactg gtaagttgca cttaggacac gcctgggata cgacgcttca
     2101 agatattatc attcgtcaaa aacgcatgca gggctttgat acgctttggc ttccagggat
     2161 ggaccatgca ggaattgcga cacaggctaa ggtagaggag cgtctgcgcg agcaggggat
     2221 ttctcgttac gaccttggtc gtgacaaatt cctagacaag gtctgggagt ggaaagacga
     2281 atatgccact acgattaaag agcagtgggg caaaatgggg ctttctgtgg actacagccg
     2341 tgagcgcttc acccttgatg agggcttgtc aaaagcagtt cgcaaggttt ttgttgacct
     2401 ctacaaaaaa ggctggattt accgtggtga attcatcatc aactgggatc ctgctgccag
     2461 aactgccctt tctgacatcg aggttatcca caaggatgtt gagggagctt tctatcacat
     2521 gaactatatg ttggaagatg gctcacgcgc ccttcaagtg gcaacaacgc gaccagaaac
     2581 catgtttgga gacgttgccg ttgccgtaaa cccagaagat cctcgttaca aagatttgat
     2641 tggcaaaaat gttattttac caatcgtgaa taaattgatt ccaatcgtgg gtgacgagca
     2701 tgctgaccct gaatttggga ctggagttgt gaaaatcacg cctgcccatg atcctaacga
     2761 tttcgaggtt ggtcaacgcc ataatctacc acaagtgaat gtcatgaacg atgacggtac
     2821 catgaatgag ttagctggcg actttgcagg catggaccgt tttgaagctc gtcaagctac
     2881 cgttgctaaa cttgaagaac ttggtgccct agtaaacatc gaaaaacgtg ttcactcagt
     2941 aggtcactca gaacgttctg gtgcagtcgt tgagcctcgt ctatccaccc aatggtttgt
     3001 aaaaatggat gagcttgcta aacaagctat ggacaaccaa gaaacagata accgagtaga
     3061 tttctaccca ccacgcttta atgatacctt ccttcaatgg atggaaaatg tccatgactg
     3121 ggtaatctcg cgtcagcttt ggtgggggca ccaaattcct gcttggtaca atgcagaagg
     3181 tgagatttac gttggcgaag aagcaccaga aggtgatggc tggactcaag atgaagatgt
     3241 tcttgacact tggttctcat ctgctttatg gccgttctca actatggggt ggcctgacac
     3301 agatgtagaa gatttcaaac gttatttccc aacctcaacc ttagtaacag gttatgacat
     3361 cattttcttc tgggtgtcac gtatgatttt ccaatcgctt gaatttaccg ggcgtcagcc
     3421 attccaaaat gtcctgattc acggtcttat tcgtgacgaa gaaggacgca aaatgtctaa
     3481 atcattgggg aacgggattg atccgatgga tgtcattgag aaatatggtg ccgatagctt
     3541 acgttggttc ctctcaaacg gctctgcccc aggacaagac gtgcgtttct catacgaaaa
     3601 aatggacgcc tcttggaatt tcattaataa aatttggaat atttctcgct atatcctcat
     3661 gaataatgaa gggttgacct tggaagaagc tgaaagtaat gtggctaagg tagctgcctc
     3721 agaagctgga aatgtgactg accaatggat tctccacaat ctcaatgaaa ccatcgctaa
     3781 agtgacagaa aactttgaca agtttgagtt tggtgtggca ggacacattc tttacaactt
     3841 catctgggaa gaatttgcca actggtatgt ggaattgacc aaggaagtgc tatatagcga
     3901 caacgaagct gaaaaagtta tcacgcgctc tgtccttctt tatactttgg acaagattgt
     3961 acgtctcctt cacccaatca tgccatttgt aacagaagaa atttacgctc aatatgccca
     4021 aggttctatt gtgacggtgg actatcctgt ggttcgccca gcttttgaaa atgaagctgc
     4081 gcataaaggt gtggaaaggt tgaaagacct gattcgtgca gttcgtaatg cgcgcgctga
     4141 agttaacgtg gcaccatcaa aaccaatcac cattttggtg aagacagcag atagtgagtt
     4201 ggaagacttc ttcaccagca acgtgaacta catcaaacgt ttcaccaatc ctgaaaaatt
     4261 agaaatcagc tcagccattg ctgcgccaga gctggctatg accagtatca tcacaggtgc
     4321 tgaaatctac ttgccactag cagatttgct taacgtggaa gaagaactcg ctcgcctaga
     4381 taaagaactg gctaaatggc aaaaagaatt ggacatggtc ggcaaaaaac tcggaaacga
     4441 acgctttgta gccaacgcca aaccagaagt catccaaaaa gaaaaagaca aacaagccga
     4501 ctaccaagcc aaatacgacg caacccaaga acggattgca gagatgaaga aaattaaatc
     4561 atagtgttta gaacgcagtt gaaaaactgt gttcttttct tactaataga gatattagat
     4621 tgaagtttaa ttatgagaaa aacgctttct ttatttaaag agttatgtta caatactatt
     4681 acaatcatcg tacaaatagt gttattttga ggggcatatg agaatgattt tagcacacta
     4741 tgactgtaaa aaagataaaa agcaatcttt agatgagcat ttatggcatg tggcctgttc
     4801 tagtcgacag gaagcatcta taattggtca aggagatgtg ctttttttaa ttggtcttta
     4861 ccacgacctg ggcaaagctg atcgaacctt tcaagataaa ttattaaata atccaaatcg
     4921 gcatgttgat cactcttatg caggggcaaa atacttatgt tctattattg ggcctcatct
     4981 aaaaaaccga ggggttgata aaaatgagag aatgacattc aacgaaatgg tggggtatgt
     5041 catctctgct catcatggga tgtatgattt atgctactat tttgacgatg ctgaatatta
     5101 tggctttaat aagtttaaaa atcgtatcaa tagagactta gatggttatc actatcatga
     5161 agatattaaa gggtacgctc taaaattaga aaaaaaatta tgtgattatg gctacaaaga
     5221 tttaagggag cttattgata aagcttttga taattaccaa caagccatgt cttccttaaa
     5281 ctggcaagat aagagtgagt gggattatta tcagtcttgt atggtgagac tttacttgtc
     5341 actcttaaaa aacgctgata ttttggacac agtaaatgcc tatggcctta agataagtcc
     5401 tatggataaa acagagcgat cctttctaaa acactcctat ttagcggcca ttgaacaaaa
     5461 atatgctagc tttggacagc caaacaatca gttgaacact attcggacag aaatcgctga
     5521 gcgtgttaaa gaaagaggta aacgagattc caaggggatt tatcgcttag atttaccgac
     5581 aggagctggc aagactaatc ttagtatgcg ttatgcgttt caccaattag ttcatcacga
     5641 caaatcaagg tttttttaca taacgccctt tctttcggtt cttgaacaaa atgcttccga
     5701 aattagaaaa gttacaggtg accttggcgt cctagaacac cattccaatg tggtgaaaca
     5761 ggctaatgaa gatgatgatg acaaggacag tttattgtca gcttatctta gtgatagctg
     5821 ggacagtcaa gtagtcttga cttctatggt tcaatttttc caaacacttt tcaaaacaaa
     5881 atcagctaat ctgagacgtt tttcaagttt gattaatagt gttgtgattc tagatgaagt
     5941 tcaatccctg cctattgaag tcaccacttt gtttaattta acgatgaatt ttttaaataa
     6001 agttatggat acaaccatcg ttctttgcac agcaacacaa cctgcttatg attcttcaga
     6061 gattgaccat cgtatctgtt atggagggaa cttgggagaa ttagctgaaa tcgttgagtt
     6121 aacgattgaa gaaaaacaga ttttttcaag gacagagctt agaaaatttg atgatagtga
     6181 tcagaaagtt cacttgactg atgttattaa tcttattcta ggtgaggaaa actcagttct
     6241 tgctattttt aatacgaaaa aaacggttca taactgctat actatgctaa aagacattac
     6301 tgatagaccg gtctatcagc tttcgacaaa tatgtgtgcg cagcatagac ttgacttgat
     6361 tgctaagatc aaaacggagt tacaaaataa tatccctatt atttgtatta gcacgcaatt
     6421 aattgaagca ggtgtagatg ttgattttca tcgcgtcatt cgttcctact cagggattga
     6481 ttctattgtt caggctgctg gacggtgtaa ccgagaaggc aaacgagata aagggcaagt
     6541 cactcttgtc aatctgacca atgaagagga aaatatttct aggctgacag aaataaaagc
     6601 taaaaaagaa gccacagaat ctattcttca taagattggg tctccaattg atatctcaac
     6661 tttaaaccgt gacttttttg agtattatta tgccaataat cagggactga tggattatcc
     6721 tttggaagac aacctatcaa tctacgacta tttaagcctt aatatttatc agacggcaaa
     6781 taaaaagttc aaaggtaagt taaaacaagc ttttaaaaca gcaggagcca aaatgaacct
     6841 catcaataat gatatgatag gaattctcgt accttatggc gaagctgaga aaaaattggc
     6901 ttatttagaa gaattgggta tgtctcactt tttatcagca gaagattatc aaacgataaa
     6961 atcattacta aaagagttac aaccttttac ggttaatgtc cgcgagaacg atcctctctt
     7021 tgagacaaca aaatcttatc taaatggtca gattctggtt ttgacgtcgg agtattatga
     7081 cacggaaaga ggagttaaat acgattcagc tagcttttac ttctaactca aaacgaaagc
     7141 agattaacaa aaggttgtta gaggaccttg ttaacctgcc aatcatcatt aataattatt
     7201 atcaatttag actatttaat aaaattagat tacaaaaaaa cagaaggagg aaagtagctt
     7261 gtacagatct agagacttct acgtgagagt aagtggtcag cgagctcttt ttacaaatcc
     7321 agccacaaaa gggggatcgg aacgctcatc ctattcggtt ccgactagac aggcactgaa
     7381 tggtatcgtt gatgccatct attataagcc gacctttact aatatcgtca cagaggttaa
     7441 ggttattaac cagattcaaa ccgaattaca gggtgtcagg gctctgttac atgattatag
     7501 tgcagattta agttatgtat cctatttgag tgatgttgtt tatctgatca agtttcattt
     7561 tgtttggaat gaagatagaa aagatttgaa ctcagataga cttccagcta aacatgaagc
     7621 cattatggag cgttctattc gtaaaggggg acgtcgagat gtgtttttgg gtacaagaga
     7681 atgtttaggg cttgtagatg atatcagcca agaagagtat gagactactg tgtcgtatta
     7741 taatggtgtc aatatcgact tgggaatcat gttccattcc tttgcctatc cgaaggacaa
     7801 aaagacacca ttaaaatcat actttacaaa gactgtgatg aaaaatggag tcattacgtt
     7861 taaagcacag tctgaatgcg atattgttaa cacgctttct agttatgctt ttaaagcacc
     7921 agaggagata aaatcggtta acgatgaatg catggagtat gatgccatgg agaaaggaga
     7981 aaactgatgg atttttttac ttctctcttg aagacttatg aaaaagcaga gctagcagac
     8041 ttggttgatc accaaaaaag aagtaatgag ccggttttac tgccgattta tcatacgagt
     8101 ttaaagtcaa atggcaaaaa tatcatttca gtgaaacttg acaaagatgg ccagtttcac
     8161 aaggcagaat ttatggcaga taagcaaatg attatttttc ctgtaacggc tgattctgtt
     8221 gctaggtcag gtagtcatcc tgcaccgcat cccctagtcg ataaatttgc ttattatagt
     8281 gctgaaatgg ggcagtctca gtatgattct tttcataagc aacttaataa ctggattgat
     8341 tattgtgagg agggtgacgt caagaggttt ttaaccattg ttcagcaatt tattttgaaa
     8401 ccagaatttc tgacactgat tctcgattct ttaattggtc ctgattatca aaataatcaa
     8461 ttaaaagtca cattttgtga tgccactgga aaagaaaaat taattgattt atcagcttgc
     8521 tttttagaat tttcaattga tcagttccag ggctttaaaa atgaatcggt ttcgacattt
     8581 aaaactttac accaatccta tatttctttt gttgaagcca atcgtgaaaa gcttggtatt
     8641 tgtaatatta gtggacgaga ggaacagctt accgataagc atagaggttt gatggggaat
     8701 gctaaaatca tctctgttag taataaaaga gaagcttata aaggacgttt tagagaacgt
     8761 gaagatgttt ttagtgttgg ctatgaaact tccgaaaaga ttcatttaat gctcaagtac
     8821 cttttagaaa ataaaaatac cagtacttgg ttagggtctt ctcaatattt aatcaactgg
     8881 tttagtgatg atttaacaaa tgatagtcgg ttggatatcg tatcaccaat ctttgatgac
     8941 ggacttgaag aagatgatga tgacgatacg cctcctgtta taacattagc aactgaagac
     9001 aataaaagaa ttggtaaatc attcatcaag ggacaaaaat tatttgctaa tgatgccact
     9061 tactacgttg ctattttgaa taaaaccagc aatgggcgga ttgctttaaa atattttcgt
     9121 cagcttcaag cgtcccaatt actcaccaat cttaacaagt ggcaggaaac atacagttgg
     9181 gagtcgcgat ctgagtttgg aaaaagtcgc ttaagaaccc ctacttttca tgacatcctt
     9241 aatgtgtcct acggggttga tagggatcgc ttccttgaat tagataatga taacttcaaa
     9301 agtgatcaaa ttcaaaagtt agtggcaagt ttgattgatg gtaaaccgat gccacagtcc
     9361 attgtcaaaa agttaggtaa caatgttaaa gaacgacatc gttaccgtaa gcactggtat
     9421 caagttgagc aggtctgctt agcaatttta cacaaacaaa atggggagga attttcaccg
     9481 atgctagatc ataccaatca aaatcgttcc tatctttttg gacgattatt agcaattttt
     9541 gaattaatcg agaccttgcg ttatggcttg gatggaaaca ataacgaccg tattaccaat
     9601 gctgaacgtt attggacagc ctatactgga caaccaacaa aattgatgat gttattggaa
     9661 aataaaatta agccttacga agaaccattg aaattaaatc gtcgtggcag ttggatgaaa
     9721 ttagaaaaag aaaaagaaga gattttagaa ctgttaaatc ctctgttaga aacagaaaca
     9781 atggaaaaac ccttagatta ccgctttatt tttgggtatt atgctgagaa aaactattac
     9841 tatacaaaac aaaacactga agtaacagaa agtgaggagt aaaaagatgt tggaacacaa
     9901 aattgatttt atggtaactc ttgaagtgaa agaagcaaat gcaaatggtg atcccttaaa
     9961 tggaaacatg cctcgtacag atgccaaagg atatggtgtg atgagtgatg tctccatcaa
    10021 acgtaagatt cgtaatcgtt tgcaagatat ggggaagtct atttttgtgc aagctaatga
    10081 acgtattgaa gatgactttc gttcactaga aagacgcttt tcacaacatt ttacagctaa
    10141 gacacctgac aaagaaattg aagaaaaagc aaatgcatta tggtttgatg ttcgtgcttt
    10201 tggacaagtt tttacttatc tgaaaaaatc aattggggtg cgtggaccag tttccatcag
    10261 tatggctaag tccttggagc caattgtcat ttccagcctt caaattacgc gtagtaccaa
    10321 tggtatggaa gctaagaata atagtggccg ctcttctgat acgatgggga caaaacattt
    10381 tgtagattat ggtgtgtatg tacttaaagg ttctatcaat gcttattttg ctgaaaagac
    10441 tggtttttct caggaagatg ctgaggctat taaagaagtt ttggttagct tgtttgaaaa
    10501 tgatgcgtcg tctgcacgtc cggaaggctc tatgcgagtt tgtgaagtct tttggtttac
    10561 gcattcaagc aaactgggga atgtttcaag tgcgcgtgtc tttgacttgt tagagtatca
    10621 tcaatcaata gaagaaaaaa gcacttatga cgcttatcag attcatctaa atcaagaaaa
    10681 attggctaaa tatgaagcga aagggttaac ggttgaaatc ctagaaggac tctagtatgg
    10741 tctatgccga agatgattat ttaatgctat caggtattca gcatttccaa ttttgtaaac
    10801 gtcaatgggc gttgatccat attgagcaac aatggcttga taatgaagcg acagcgcatg
    10861 gacaggtttt acatactaaa gcagataacc cttacattaa agaaaaacga aaagagcttt
    10921 tggtctcacg tgctatgccc atttcttctg cagaacttgg actttcagga attatggatg
    10981 ttgtggaatt ttataaagat gatcaaggtg tgtctttgag gggaaaacgt gggaaatggt
    11041 taccaaaagt tgtggaatac aagcgcggaa aacctaaaaa agataccaga gatattgtcc
    11101 agttggtggc tcagaccatg tgtttagaag aaacgctaga ctgcgacatt aacgaaggtt
    11161 gtctttatta ccatagtgtc aatcaaagag tgattgttcc tatgacatca gctttgcgtc
    11221 aagaagtgaa ggaattagcc gcagagatgc aagaggttta tcagagtcaa atgctaccta
    11281 aagcagctta ttttaaaaac tgtcagcttt gttctttagt cgatatttgt aagcccaggt
    11341 tgagtaaaaa aacaaggagt gtgtcgcgtt acatcaatga ggctatgacc agtgaggaga
    11401 tggacctatg aaaaagttgc taaatacctt gtatttgacg caagaagatt tttatgtcac
    11461 taaagagggc gataacattg ttatcaagca agaaggtaag gttctcaaac ggtttccgtt
    11521 tcggattatt gacggtattg tctgtttttc ttatttgggt gtgtcgcctg ctttggtgaa
    11581 gttatgtacg gagaatcaga ttaatttatc gtttcataca ccacaagggc gtttttgtgg
    11641 tcgctatatt ggttcaacca atgggaatgt gttgttgcgt agagaacatt atcgtttatc
    11701 tgatcgtgag gaatctttgg aatacgcaaa gcggtttatt ttggctaaaa tttccaactc
    11761 aaggaaatac ttgctacgct ttaaacgaga tcatcgtcaa cagattgata ccaagctttt
    11821 tgaggctgtt aatgacgaat tgatatgggc tttagagatg gttcaggcag cagataataa
    11881 agactcttta agagggattg aaggccaagc tgctaatcag tattttcgca tatttaatga
    11941 cctggtgttg acggacaaaa aaacgtttta cttccaaggt cggagtaaac gaccaccctt
    12001 agattgtgtt aatgccctct tgtcttttgg ttacagttta ctgacctttg aatgtcaatc
    12061 tgccttggaa gctgtcggat tagacagtta cgttggtttc tttcacacgg atcgtcctgg
    12121 gtgtgctagt ttagcgcttg atttagttga agagttccgc tcatatattg tagatcgttt
    12181 tgtcttttca ttaattaata aaggacaact tcagaaaaaa cactttgagg ttaaagaaaa
    12241 tggtagtatt ttaatgacgg aaaatggcag agctattttt attgatttgt ggcagaagcg
    12301 taagcatact gaggtagaac atccttttac aaaagagaaa gtaaaactta tgttattacc
    12361 ctatgtacaa gcgcagcttt tagctaaggc catacgagga gatttagaaa gctatccacc
    12421 ttttatggtt taggagatgt tatatgatgg ttttagtcac ttatgatgta aatacggaaa
    12481 cacctgctgg tagaaaaaga ttgcgtcatg ttgccaaact ctgtgtggac tatgggcaac
    12541 gtgttcaaaa ttctgttttt gaatgttctg tgacacccgc agaatttgtg gatataaagc
    12601 accgcttaac acaaatcatt gatgagaaaa ctgatagtat tcgcttttat ttattgggga
    12661 aaaattggca gaggcgtgtg gaaacacttg gtcgctcaga cagctatgac ccagataaag
    12721 gtgtcttatt attgtaaaaa tctcttgtgc gaagctagct ttcacagaaa caccttgctt
    12781 gctcgcgcaa aaataactta aaaaagaagc gaaatggaga taaaaaggct taaaacacct
    12841 ctatgtgtgc catccgtttc tctataaact gtgtcatttg gcgcagtctc acccttcatg
    12901 ggtgagtgga ttgaaataaa taattacatg actagccaat acacccacat agtctcaccc
    12961 ttcatgggtg agtggattga aatttcatga gcttctttac tctcaaagta agagtggtct
    13021 cacccttcat gggtgagtgg attgaaagat gaacccgacc tctcttttaa tgaggtcggg
    13081 tttttacatg cctttagtca accatttatc tgatagcgta tcaaattcaa gtttttgcat
    13141 gttctagtct atggtttgcg ccactagctt tcggtaaact aagggtaact taagagagga
    13201 gttatttatg acactatcac ttgtattaat ggtatcggtt tttggggcag gcttgttatc
    13261 ctttttctct ccgtgtatct ttccggtcct tcctgtttat ttaggcattt tactggatgc
    13321 agatgattca aagacgatta ctatatttgg taaaaaactc tattggtatg gcattgtcaa
    13381 aaccttagcc tttatttttg gtctatctac tatttttgtg attttaggtt acggggctgg
    13441 ttttttagga aatatccttt atgcggtatg gtttcggtac ttactgggag ccttggtcat
    13501 tatcttgggg attcatcaga tgggcctcat taccattaag agcttacaat ttcaaaaatc
    13561 actgactttc cataataaca agaatcgcaa cggtttgttc aatgcattta tccttggttt
    13621 aacctttagc tttggttgga cgccttgtgt gggacctgtt ttgagttctg ttctagcttt
    13681 ggtggcttca gggggaaatg gtgcctggca aggtggcgtt ttgatgatta tttatactct
    13741 tggattgggc attcctttcc tactcatctc ttttgcgtca ggcattgttt tgaaacagtt
    13801 taacaagctc aaaccccaca tatttttact gaaaaaagta ggaggcgttc tgattatagt
    13861 catgggaatc ttgcttatga caggaacctt aaataactta gcacaacttt ttggataaag
    13921 gagaaacaca atgaaaaaag gactattagt aacaactggt ttggcttgtc tcgggctact
    13981 aactgcttgc tcaacccaag acaatatggt taaaaaggaa ataactcagg acaagatgag
    14041 catggcagtt aaaaagaaag ataagatgtc aacatcaaag gacaagtcca tgatggcaga
    14101 taaatcatct gataagaaaa tgaccaatga tggtcctatg gcgcctgatt tcgaactcaa
    14161 aggcatcgat ggtaaaacct atcgcttatc agaattcaaa ggtaaaaaag tttatttgaa
    14221 attttgggcc tcttggtgtt caatctgttt atcaaccttg gcagataccg aagacctggc
    14281 taaaatgtca gataaagact atgtggtctt aaccgtcgtc tcgccaggtc atcaaggaga
    14341 aaaatcagaa gcagacttta caaaatggtt ccaaggaaca gactataagg acttaccagt
    14401 cttgttagat ccggatggca agctattgga agcttacggc gtcagatctt acccaacaga
    14461 agttttcatt ggaagtgatg gtgttcttgc taaaaaacac attggttatg ccaaaaaatc
    14521 agacatcaaa aagaccctta aaggtataca ttaggaagga ccagctgata ggcattagaa
    14581 aaaaggagtt gagtttatgg aacacaaatg gaaattatgg ctatttatcg ttggagtggt
    14641 cttgttaata ggcggagctt ctgttctcat tcagaaaggt caagccaagg cttttagtca
    14701 aggcaagcct caactaccag ctaaaaaagt caaatccact aaagtagatc ccaatgcccc
    14761 tgttgatcaa aaagtgattt acctggctgg aggctgtttc tggggcgttg aagaatattt
    14821 ttcacaagtg gatggcgttc tagatgcggt gtcaggctat gccaatggta gaggcgatac
    14881 caccaactac cagttaattc atcagactgg tcatgcagaa accgttgaag tgacctatga
    14941 tgcgaaccgt attagcttga aagaattatt actgcatttt ttccgaatta ttgacccaac
    15001 cagtcttaat aagcaaggaa atgatcgcgg tagtcaatac cgaactggga tttactatac
    15061 tgacaaagca gatttagcta ttattgatga ggtcttcaaa gaaaaagcca aggattacaa
    15121 gaaaaaaata gtggttgaaa aagcaccatt gaaacacttt attaaggcag aagactacca
    15181 ccaagattac ctcaagaaaa atccaaatgg ctactgccat attgacatca accaagcgac
    15241 ttatcctgtg attgatgaaa gcaagtaccc aaaaccaagt gccactgaga tcaaagcaaa
    15301 actatctgca gacgaatacc gagtgacgca aaaaaacgaa actgaaaaag ccttttctaa
    15361 tcgctactgg gattcttttg atgcaggaat ttacgtagac gttgtgacag gagaaccgct
    15421 tttctcttca aaagacaaat ttgaatcagg ttgtggttgg ccaagtttta gccgccccat
    15481 cagcccagac gttgtccgct acaaggaaga taagagtttc aatatgacga gaacagaagt
    15541 gcgcagccgt tcagggaatt ctcatctggg gcatgtcttt actgacggac ctaaagacca
    15601 aggcggcctt cgttactgca tcaatagctt gtctattacc tttattccaa aagctgatat
    15661 ggaagctaag ggctatggtt atttattatc atctgtagaa tagggttagg cctaaaaatc
    15721 tgatataata gaagaaagac tagtatgaga gggccatgca aggcccttta taaagataag
    15781 gagacaccgt gtgtactcat tgttaattgt agaagacgaa taccttgtgc gccagggtat
    15841 tcgttctttg gttgatttta gccagttcaa gattgatagg gtcaacgaag cagaaaatgg
    15901 ccagttggct tgggacttgt ttcagaaaga gccttatgat attgttttga cggatatcaa
    15961 tatgcccaaa ttaaatggga ttcaactagc agaactcatt aaacaggaat ccccccaaac
    16021 tcatctggta tttttgacgg gctacgatga ttttaactat gccttatctg ctttgaagtt
    16081 aggggcagat gattacttgc tcaaaccctt ttccaaggcc gatgtggaag atatgttagg
    16141 aaagctccag caaaaattag acctttccaa gaaaacagaa accatccagg aattggttga
    16201 gcagcctcaa aaagaagtat cagcaatagc aatggctatt catgagcgat tggcagattc
    16261 tgatttgacc ctaaaaagct tggctcagca gcttggtttt agccctaatt accttagcgt
    16321 cttgattaaa aaagatttag ggatgccctt tcaagattat ctggtacaag aacggttgaa
    16381 aaaagccaag cttctcttgt taaccagtaa tcttaaaatc tatgaaattg cagagcaggt
    16441 cggttttgag gacatgaatt atttttctca gcgctttaag caactggtag gcgttacccc
    16501 aagtcagtat aaaaaaggag gccaggcatg aagcgttatc ccctactggt ccagttgatt
    16561 tcgtatgttt ttgtgatcgt aattgccctc attaccacgc ttggtttgct ttattaccag
    16621 acgagttctc gtaatatcag gcaactaatt gaacgtgata cccggcagag cattcggcaa
    16681 agttcccaat ttattgacgc ttacatcaag cctcttaaag aaacaacttc ggtgctggcg
    16741 aaaaatacgg aaattcaagc ctttgctagt caaattcatc aagaaaatga caaacaggtt
    16801 cttcagctca tgaagatggt tcttgcgacc aattccgatt tacaagcagc tgttctggtg
    16861 actaaggatg gtcgaacggt gtctaccaat tctcagttga ccatgaaaac ctctagtgac
    16921 atgatggcag aaccctggta taaagcagcc atagaccgtc aggccatgcc agtcttgacc
    16981 ccagctcggc aattatccct ttcttctaaa aaagaatggg tagtttctgt gacccaagag
    17041 gtagtagata gggctgggca taatttaggt gtgctaagac ttgatattgc atacccgacc
    17101 attaaagcgt ctttagatca gcttcagcta ggccgccaag gctttgcctt tattgtgaat
    17161 gataagcatg aatttgttta ccatcccaaa aagagtgttt acagttcttc taaggagatg
    17221 gctgcgatga agccttattt agcgattcag aatggttaca ctaaggacaa gacatctttt
    17281 gtttaccaaa aactcattcc taacagtcaa tggactttag tgggagtggc gtcactggat
    17341 cagttgcacc gggtgcagcg ccaaattttt tggtcctttc ttggaacagg gcttctagcc
    17401 tgtctgattt gtggctttgc aactgtctta gccttacgca gatggattcg tcccattcaa
    17461 caattgcagc aagttattct tgctattcaa aaaggagatc gtcagttacg tgcccaagaa
    17521 acgggttctc cagaattgac aaaccttgcc caacagttta atgcgctctt agatcaaatt
    17581 gatagcttga tggttgccgt tgcggataag gaaaaggcga ttgggcagta taggttacaa
    17641 gccttggcta gtcagattaa cccgcatttt ctctataaca ccttggacac tattatttgg
    17701 atggcagaat ttaatgacag caagcgcgtg gtagaagtga ccaagtctct agctaagtat
    17761 tttcgtttgg cccttaatca ggggaacgaa tacattcgtt tggcagatga actggatcac
    17821 gttagccaat acctctttat tcaaaaacag cgctatggag acaagctaag ttatgaagtg
    17881 caaggcttag atgtctacgc agactttgtt attcctaagc ttatcttaca gcccttagta
    17941 gaaaatgcta tctaccatgg catcaaagaa gtcgatcgca aaggcatgat caaggttacg
    18001 gtatctgata cagctcagca tctggtgttg actgtttggg ataatggtaa aggcattgaa
    18061 gactcttcac tgaccaatag tcagagcttg ttggctaggg gaggtgtggg ccttaaaaat
    18121 gttgaccagc ggttaaaact tcactatggt gaaggctacc acatgaccat tcatagccag
    18181 tcagaccagt tcactgaaat acaattaacc cttcctaaaa tgcatgaatt aatggcagac
    18241 gacacacagg aaaatgagta aggttacagg aagtgcatgt cagccatttc cctaagttag
    18301 ggtattggag ataagaacct tagaaaggat atcatgagtt tagcatctga ctattttagc
    18361 cgacagaccc ccatagttga aaagctaatg gcttacggtt ttgaaaaacg aaataatggt
    18421 tacttctata acgaacggtt tatggaagaa gaatttgagg cgcagcttag gattgatgag
    18481 gctggcaata tctgggatcg ggttattgat tgtgacttgg aggaggatta tttgccttta
    18541 caacaagcag cctggcaagg aacctatact gggcaggtta gagcagccta tttggaactc
    18601 ttggagcgct tatcagtagc ctgttttgaa gtcactcctt ttcagtcaat gcaagctaat
    18661 agacttgcta agcatatcac caaagaatgg tctgacccaa tggactatcc ttttgaaaag
    18721 cacccagacc ttgcaaccta tcgggtagag ggcaaatggt atgctatgat tttttctctc
    18781 ttggctgata aattagacca gataccagag agattagtag gacagacatg tgaagtgatg
    18841 actgtcaaag ttaatcccaa ggctttccct cagttactgc agcaagaagg catttaccca
    18901 gcgtatcaca tgtcaaagaa aaactggatt agtattattt tggatgataa ggtaacagat
    18961 gataagcttt ggacgttagt aactcaaagt cgtcaactag tcaacccaaa cggtctttct
    19021 aatcctaatg gtcctgatta ttgggttatt ccagctaatt tgaaatacta tgatattgat
    19081 gcagaatttg cagccaatga tgtgatttta tggacccaaa aagctggtat tgccgtggga
    19141 gactatgtgc tgatttatat aacagcccca gtcaaatcca ttcgctatgt ctgccaagtt
    19201 ctagaaacca atatacctaa cgaaggctat cgtaaaaatc ctaacattga caaactcatg
    19261 cgtctccgaa aacgccaaca gtacaaggat ggtctcttgt cttttgacct tatgaaaaaa
    19321 catggcgtag ctgcagtgag agggccaaga cgattaagcc ctcaattaat tgcattttta
    19381 aaggaaaaag agtattttaa agagaacaac taaaggagaa taagagatgg ttgaatttgt
    19441 agcagatcaa agtttttggg aactttttcc agatgccaaa ctaggtgtcg tcttattaaa
    19501 ggatgttcag aatcaagcag agtcaccaga agatgtcaaa cagctcttag cagacagcca
    19561 tgagttagca aaagcttatt taacagcaga caattttagt gataatcagg tggttcaagt
    19621 ctaccgcaag gcctatcaac actttaaaac caaaaaagga gctcgctcta gcattgaagc
    19681 ccttctcaag cgggtgtcaa atggtcaaag cattccgtcg atcaatccgc tagtggatat
    19741 ttataatgca gctagtctac gttttggttt acctgttgga gccgaagata gtgacagttt
    19801 tatcggagat ttgcgtctga cgataacaga cggtggtgac gacttttact tgattgggga
    19861 tgctgacaat aacccaacct tgccaaatga gctgtgttat aaagatgata ttggagcggt
    19921 ttgtcgttgc cttaactggc gagatggcga acgcaccatg gtgacagaac acaccaaaaa
    19981 tgcatttttg attatcgaag ctcttgatca agaaggtcaa aatagattgc aagaagctct
    20041 tgacttcatt gaaggcagcg caaaaatgta ccttcatgca atcacctctg tgcatgtgtt
    20101 ggataaagac aatccacacg tgccactttt tacggaaaac tagattagta ggatgaactg
    20161 tgtaaaatag aaggttaaca aaaaagcgag taaacgaatg tcctgtcatt taggtttttg
    20221 tttactcgct ttttgatgag attttactgc tgtcctagca aaaggtgagg atgaggtcgt
    20281 atatcacata gaggttttct gttaagcctt atttgttact aaagaagaat ggtggtgtgt
    20341 aatgactaag ggtctcgtaa caagccttgg cttgctcatt gtcttcacag acaatcaagc
    20401 aagtatcatc accacagatc gttgctacaa tttctggaat ttgcatggca tctaaaatgg
    20461 agccaaagga ttgggctagt ccaggtaacg tttttaaaat aatttgatgt tgaactatct
    20521 ttaacatgac caaagcgtct tccatgtaaa aacgaagacg atgttcccag cgggtttgtg
    20581 aaatggctaa cgcttcatag tgtgtgtcgt ttccggaagt tactttgacc aggttcaatt
    20641 ccttcatgtc acgtgatagg gtagcctgag tgatcgtgat gccatttttt tgcaaccgtt
    20701 cttgtaattc ttgctgtgta tgtatagttg tctcagagat gagggaacgt atgagttggt
    20761 gacgcgtctc tttcttattc attgttataa tcttccttta acgtaattga taacaatccg
    20821 agtatagcaa aaagaggaga aggtgtaaag tttttgatga accgcttaca aaatggcttt
    20881 tttatggtaa aataaagatg atgtttagaa aaaggagatt tgtgtgattc gaagagaaga
    20941 ttatcaatac cttagaaaac taaacgattt tcgctacttt tctattgaac aatttgacaa
    21001 aattgtaggg cagatggaat tccgaaaagc taaaaaggac catatccttt tttttgaggg
    21061 agataaaaga gataagcttt ttctagtgac ctctggttat ttcaaggtgg agcagtccga
    21121 tcaatcagga accttcatgt atacggattt catcagacac ggtaccattt ttccttacgg
    21181 tggcctcttt acagatgatt attaccattt ttcagtggta gccatgacag acgtgactta
    21241 tttttacttt ccagtcgatt tatttgaaga ttattcgctt gaaaatcgtc tacaaatgaa
    21301 acacttatat agtaagatgt ctaaactgct cgagttacat gagttgaggg ttcgaaattt
    21361 gattacatca agtgctagtt ctcgtgtgat tcagtctctg gcgattttgc tggttgaaat
    21421 gggtaaagac agtgatacct taccttttca attaacaaca acagatattg ctcaaataag
    21481 tgggacgaca agagaaactg ttagccatgt gcttagggat ttgaagaagc aagaattgat
    21541 taccataaaa ggtaagtatt tgacttatct agataaagac tattttttac aatacacaaa
    21601 gtg
//
LOCUS       DATWVB010000027        21191 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.027, whole genome shotgun sequence.
ACCESSION   DATWVB010000027 DATWVB010000000
VERSION     DATWVB010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21191
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.027"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(525..911)
                     /gene="rplQ"
                     /locus_tag="VCX65_001176"
     CDS             complement(525..911)
                     /gene="rplQ"
                     /locus_tag="VCX65_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEP5053639.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(926..1864)
                     /locus_tag="VCX65_001177"
     CDS             complement(926..1864)
                     /locus_tag="VCX65_001177"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEP5053640.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1910..2293)
                     /gene="rpsK"
                     /locus_tag="VCX65_001178"
     CDS             complement(1910..2293)
                     /gene="rpsK"
                     /locus_tag="VCX65_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEP5053641.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2311..2676)
                     /gene="rpsM"
                     /locus_tag="VCX65_001179"
     CDS             complement(2311..2676)
                     /gene="rpsM"
                     /locus_tag="VCX65_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEP5053642.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2694..2810)
                     /gene="rpmJ"
                     /locus_tag="VCX65_001180"
     CDS             complement(2694..2810)
                     /gene="rpmJ"
                     /locus_tag="VCX65_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEP5053643.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2836..3054)
                     /gene="infA"
                     /locus_tag="VCX65_001181"
     CDS             complement(2836..3054)
                     /gene="infA"
                     /locus_tag="VCX65_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEP5053644.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3172..3810)
                     /locus_tag="VCX65_001182"
     CDS             complement(3172..3810)
                     /locus_tag="VCX65_001182"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEP5053645.1"
                     /translation="MNLLIIGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3960..5264)
                     /gene="secY"
                     /locus_tag="VCX65_001183"
     CDS             complement(3960..5264)
                     /gene="secY"
                     /locus_tag="VCX65_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEP5053646.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5281..5721)
                     /gene="rplO"
                     /locus_tag="VCX65_001184"
     CDS             complement(5281..5721)
                     /gene="rplO"
                     /locus_tag="VCX65_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEP5053647.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKYAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5936..6118)
                     /gene="rpmD"
                     /locus_tag="VCX65_001185"
     CDS             complement(5936..6118)
                     /gene="rpmD"
                     /locus_tag="VCX65_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEP5053648.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(6133..6627)
                     /gene="rpsE"
                     /locus_tag="VCX65_001186"
     CDS             complement(6133..6627)
                     /gene="rpsE"
                     /locus_tag="VCX65_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEP5053649.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6646..7002)
                     /gene="rplR"
                     /locus_tag="VCX65_001187"
     CDS             complement(6646..7002)
                     /gene="rplR"
                     /locus_tag="VCX65_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEP5053650.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7107..7643)
                     /gene="rplF"
                     /locus_tag="VCX65_001188"
     CDS             complement(7107..7643)
                     /gene="rplF"
                     /locus_tag="VCX65_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEP5053651.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7846..8244)
                     /gene="rpsH"
                     /locus_tag="VCX65_001189"
     CDS             complement(7846..8244)
                     /gene="rpsH"
                     /locus_tag="VCX65_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEP5053652.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8395..8580)
                     /locus_tag="VCX65_001190"
     CDS             complement(8395..8580)
                     /locus_tag="VCX65_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEP5053653.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8596..9138)
                     /gene="rplE"
                     /locus_tag="VCX65_001191"
     CDS             complement(8596..9138)
                     /gene="rplE"
                     /locus_tag="VCX65_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEP5053654.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9162..9467)
                     /gene="rplX"
                     /locus_tag="VCX65_001192"
     CDS             complement(9162..9467)
                     /gene="rplX"
                     /locus_tag="VCX65_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEP5053655.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9546..9914)
                     /gene="rplN"
                     /locus_tag="VCX65_001193"
     CDS             complement(9546..9914)
                     /gene="rplN"
                     /locus_tag="VCX65_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEP5053656.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9939..10199)
                     /gene="rpsQ"
                     /locus_tag="VCX65_001194"
     CDS             complement(9939..10199)
                     /gene="rpsQ"
                     /locus_tag="VCX65_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEP5053657.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            complement(10225..10431)
                     /locus_tag="VCX65_001195"
     CDS             complement(10225..10431)
                     /locus_tag="VCX65_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEP5053658.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10441..10854)
                     /gene="rplP"
                     /locus_tag="VCX65_001196"
     CDS             complement(10441..10854)
                     /gene="rplP"
                     /locus_tag="VCX65_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEP5053659.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10858..11511)
                     /gene="rpsC"
                     /locus_tag="VCX65_001197"
     CDS             complement(10858..11511)
                     /gene="rpsC"
                     /locus_tag="VCX65_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEP5053660.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11524..11868)
                     /gene="rplV"
                     /locus_tag="VCX65_001198"
     CDS             complement(11524..11868)
                     /gene="rplV"
                     /locus_tag="VCX65_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEP5053661.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11884..12162)
                     /gene="rpsS"
                     /locus_tag="VCX65_001199"
     CDS             complement(11884..12162)
                     /gene="rpsS"
                     /locus_tag="VCX65_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEP5053662.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VCX65_001200"
     CDS             complement(12302..13135)
                     /gene="rplB"
                     /locus_tag="VCX65_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEP5053663.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13153..13449)
                     /locus_tag="VCX65_001201"
     CDS             complement(13153..13449)
                     /locus_tag="VCX65_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEP5053664.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VCX65_001202"
     CDS             complement(13449..14072)
                     /gene="rplD"
                     /locus_tag="VCX65_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEP5053665.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VCX65_001203"
     CDS             complement(14096..14722)
                     /gene="rplC"
                     /locus_tag="VCX65_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEP5053666.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14970..15278)
                     /gene="rpsJ"
                     /locus_tag="VCX65_001204"
     CDS             complement(14970..15278)
                     /gene="rpsJ"
                     /locus_tag="VCX65_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEP5053667.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15477..16766)
                     /locus_tag="VCX65_001205"
     CDS             complement(15477..16766)
                     /locus_tag="VCX65_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEP5053668.1"
                     /translation="MIYNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGV
                     SIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLL
                     SVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQV
                     SLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPL
                     DKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMA
                     TATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDA
                     QRSAMVVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTIGMWVIRIGLGYVIGV
                     VWQYGLIGVWMATVLDNTSRWFILSKQFKKYQEITFH"
     gene            complement(17154..18170)
                     /gene="adhP"
                     /locus_tag="VCX65_001206"
     CDS             complement(17154..18170)
                     /gene="adhP"
                     /locus_tag="VCX65_001206"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEP5053669.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNVGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVAPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18422..21064)
                     /gene="adhE"
                     /locus_tag="VCX65_001207"
                     /gene_synonym="adhC"
     CDS             complement(18422..21064)
                     /gene="adhE"
                     /locus_tag="VCX65_001207"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEP5053670.1"
                     /translation="MTEGHNTVETTSVSVTINALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKIADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
BASE COUNT         6106 a         4490 c         3823 g         6772 t
ORIGIN      
        1 aattttgttg gaaacggctt aaagtgacag attgtaaaag taaaaaagat attttcacct
       61 ccaaattaaa agaggatttt aaaatactta ttaataaaat attgaatagg ggataaaact
      121 aacaatatag tttgagcatc tgtttgcgat gcaagttttt ttcggacatt taaacgaggg
      181 gattacaccg tttatttgcc catgagaggt ctttaaacac ctgcataagg ttttcttatt
      241 ctgatgacct tattgtctct gagaaaactt tataaacgca tcagaagagg cttctgtgtt
      301 attgttttac tcagcttaaa agcgggagtg tcacctcata atacaacaaa acgcctgctt
      361 ataaaaagtt tctatagctt agataccttt cataaacaag cgtcacatat taacaatatg
      421 atgagtgttc ccgctaggaa aaatcctagc ggtagaccag agctagacta agaataatct
      481 ctcgattact ccatcatcat aacactcaac aaaattgata aaaattaaac taattcaata
      541 attgccattg gagcagcatc tccacggcgt ggttctgttt taagaatacg agtgtatcca
      601 ccgttacgtt ctgcataacg aggtgcaatt tctgagaaaa gtttttgaag agctgtcgtt
      661 gatgtgtatt tatcggtagc ttcatcataa ttttctgatg cgatttcgtt acgaacgtat
      721 gcagctgctt ggcgacgagc atgaagatca ccacgtttac caagagtaat cattttttca
      781 actgttttac ggatttcttt tgcacgtgct tctgtcgtta caattgattc gttgatcaaa
      841 agatctgtcg tcaaatcacg aagcattgct ttacgttgtg agctagtgcg tcctagttta
      901 cggtaagcca ttttgtcctc ctatattatt tatcgttttt tagtccgaga cctaagtcag
      961 caagtttaac cttaacttct tcaaggctct tacgtccaag attacggact ttcatcattt
     1021 caggctcaga tttttctgtt aagtcgaaga cagtgttaat gcctgcacgt tttaaacagt
     1081 tatatgagcg tacggataaa tcaagctcct cgatggtgcg gtcaagtacc ttttcatcgt
     1141 tcactttttc agtttctttc attacttcgg tagcttttgc aacctctgtt aaatcagtaa
     1201 acaggtttaa gtgttcgatc aaaactcgag cagatagacc taaagcatct tcaggaataa
     1261 ttgttccgtt tgtcatgatt tcaatcgtta atttatcaaa gccatcattg ctacctacac
     1321 gggcaggttc aacttgataa ttaacttttt taactggcgt atagattgaa tctactgcca
     1381 atgtacccac aggtgcatca tcttttttgt ttccttctgc tggcacataa ccacgttttt
     1441 tagcaacagt cattgttgca cgtagagaat gtccttcagc gattgtaaaa agataatgat
     1501 ccgggttaac aagttcgata tcactgtcag taagaatatc accagctgtt acctctgctg
     1561 gtccttctac ttcaagttcg ataatctttt cgtcttcgac gtatgatttc acagcaagtc
     1621 ccttaacatt aaggataatt tgcatgacat cttcacgtac acctgggatt gtatcaaatt
     1681 cgtgtagtac tccatcaatt ttaattgatg ttactgctgc acctggaagt gaagacaaga
     1741 gtacacgacg aagagaatta cctagagttg ttccgtagcc acgttcaagt ggttcgatga
     1801 caaatctacc gtaatcttta ttttcatcaa tttttgttat tattggtttt tcaaactcaa
     1861 tcattttttc acccctcgaa acgaaacttg tgtactattt gttatatgat tatacacgac
     1921 gacgttttgg aggacgagca ccattatgtg gcacaggggt cacatcacga attgcagtta
     1981 cttcaagacc tgcagctgct agagcacgaa tagctgattc acgacctgaa ccaggacctt
     2041 ttacagtcac ttcaacagtt tttagtccgt gttcttgtgc agattttgca gcagcttctg
     2101 cagccatttg agcagcaaat ggagtagatt tacgagaacc tttgaaacca agagcaccag
     2161 ctgatgacca tgcaagagca ttaccatgca catctgtaat cataacaata gtgttattaa
     2221 atgtagcgtg aatgtgtgca acaccagatt cgatgttctt tttcacacga cgtttacgtg
     2281 ttggtttagc caattgtttt acctcctatt ttattttttc ttacctgcaa tcgcaacagc
     2341 tttcccttta cgagtgcgag cattgttttt agtattttgt ccacggacag gaagtccacg
     2401 acgatgacgg attccacggt atgaaccgat ttccatcaaa cgtttaatgt tcatgtttac
     2461 ttcacgtcga aggtcacctt caactttgat tgcatccact tcacgacgga tagcatcttc
     2521 ttgatctgat gttaaatctt taacacggat atcttcagaa atacctgcag ctgctaagat
     2581 ttttttagat gttgcaagac caattccgta aacataagta agtgaaatta ctacgcgttt
     2641 atcatttgga atatcaactc cagcaatacg agccattttt tctcctttct attttatcct
     2701 tgacgttgtt tgtgttttgg atttgtcgga caaattacca taacacgacc attacggcga
     2761 ataactttac agtattcgca aattggttta accgatggtc ttaccttcat gttttaatcc
     2821 ctccaattat ttcgattatt taaagcggta tgtgatgcgt ccacgtgtca agtcataagg
     2881 actcatttct actgtaacac ggtcacctac taaaatacga atgtaatttt tgcggatttt
     2941 tcctgataca gttgctagaa tttgatgtcc attttccaat tcaacagtaa acattgcatt
     3001 tggcatcgtt tctactactt tgccttcaat ttcaatcacg tcttcttttg ccacgcaaaa
     3061 gtacccccta aatttcgatt tgatgtcctc tgagcacaga ggtaacaatt ataagtcaga
     3121 ctaaactagt atatcattac taatctactt atgcaagtag attagtataa tttatttgag
     3181 ttctagcaac gctttttcaa catctgcaaa aacgtctgtt atttcttgat taccttcaat
     3241 atctgtaaca agaccaagct tacgatagtg ttcaagaata ggttctcctt gagccatatt
     3301 gacgtccaaa cgacgtttaa cagtttcagg cttatcatct tcacgttgat agtaatcttc
     3361 ttctttataa tctactggtg ggttgaacac tttatggaac gtttcaccag ttttacgatt
     3421 gataatacga ccactcaaac gctctacaag acatgatgga tccactttaa tattaataac
     3481 accatctaag cggagtccta gttcttcaag tgttgcatct aaggcgtgtg cttgttcaat
     3541 agtacgtgga tacccatcaa gcaaaaaacc tttttctgcg atatcatcct cagctaagcg
     3601 ctcttttaca atcccgtttg tgacttcatc aggaaccaat tcacctttat caatataact
     3661 tttagctaaa cgtcccattt cggtttgatt agccattgcg gcgcggaaca tatcccctgt
     3721 tgagatgtga gcaacaccaa attcttcaac aatcttagct gcttgggtcc ctttaccagc
     3781 tcccggcaaa cctatgatta aaagattcat cttttcctcc tcttttaaaa taaatacata
     3841 gtaggaaatt attttccttg gtttttgttt tcaaatggca acaagaaatc gtttgatgat
     3901 aaccaagtct tattgtcatt taaaaacaaa atagaaggtt gacaatgtca acctgtattc
     3961 tattctgctg tattcataaa tccgacatat tttctcttta gaagataccc ctcaagctgt
     4021 ttcatacctt cgataccagt tgaaatcaaa atgagcaaac tagttccacc taaagcaata
     4081 ctagaagaaa ggttgagagc ttgttgtgct gctattggcg ctaaagagat aaatgctaag
     4141 aagatagctc ctacggttgc tagttttttt agcaatgcgg acataaattg ttctgtctca
     4201 cgtccagggc gaacacttgg tatatatgag gaattcttct gaagattttc tgctgtcttc
     4261 tcaggattaa cttgtacaaa ggtatagaag aatgagaaca atataatcaa caaggcgtaa
     4321 actatcattc cgactggagt ttgataatta aaaatttctt gcaaacggtt taaccacggt
     4381 aaatctctac cattttggac aaaaggaata atcgtacttg ggatagttgt aatcgagcta
     4441 gcaaagataa cgggaataac gccggctgga tttactttta atggaagata tgaacttgta
     4501 ggtgcacctt gcattagctt tgtgtattgg attggaattt tatattccgc ttgttggaca
     4561 tatgttgtaa agaaaacaat agcaagaaca gctatgatta aaatcccaac aatgagataa
     4621 gacgagtgta aatcacttgc cttaacattt acaaaatagt cttcacgaat tgttgcaatt
     4681 gcacttggaa tagacgaaat aatacccgca aagataatca ttgatacgcc attaccaaat
     4741 cctttatcgg tgatttgttc tccaagccag gtaacaataa cgctacctgt tgtcagtaat
     4801 gccccgatca gtaaatatgt tttgatgtct ggtgtcttaa caagtgcaac gttcgacaaa
     4861 gtattaaacc ctgcagtgat accaatggat tgggcaaaag ccaaaacaag tgaaatatag
     4921 cgcgtcgctt gatttaattt acgacgtcca acctcacctt gtttgcccca ctcaacaaac
     4981 ttaggtaaaa tatccatctg caataactga acaacgatag aagcagtaat atatgggcta
     5041 acccccattg aaaatactga gaaatttctc atcgcattac cactaactaa gtttaacata
     5101 tttaagaaag ggagttcact taattgctct aagctcttgg catttacacc aggtacggta
     5161 atatgtgtcc caattcggaa tacaagaatg ataaatatag taaagaaaat tttattccgt
     5221 acagtcttta tctttaacgc gtcttttagt atttttaaga acataatgag tatcccctca
     5281 ttagatgact tcgattgaac cacctttagc aataatagct gcttcagcag attttgagaa
     5341 cttagctgct tttacagtca attttttagt caattcaccg ttaccaagca ctttaacgcc
     5401 tgatttttca gctcggacaa taccagcata ttttaaaata gccggagtca cttctgtacc
     5461 atcatcaaaa acattcagtt gatcaagatt cacaagtgca tattctttag tattaatatt
     5521 tgtaaagcca cgttttggaa tacgacggaa caatggtgtt tgtccacctt caaaacctaa
     5581 acgtacaccg ccaccgctac gagctttttg acctttttga ccgcgaccag atgttttacc
     5641 attacctgat gatgtcccac gaccaacacg gttacgtact ttacgtgagc cttcagcagc
     5701 ttttaattca tgaagtttca ttttttctcc tttttttgta aaatgctagc gcctctatga
     5761 gggaaaagga ctccctatag aaactcgcct atacattaat gatacttaag ttatccaaaa
     5821 taacttaata cagatacgca ctaaccgact actgtttgtt gccaaaaaag caaactacaa
     5881 gagtcggttt tgtgctcgtt tttaattatg aaatcagaga tttcacagtt ataacttatt
     5941 taacatcttc aacggtaacc aagtgagaaa tagctgtcac cataccacgg atagcagcat
     6001 tatcttcttt gactactgaa gagtttaatt taccaagtcc aagagcaaca acagttttac
     6061 gttgttctgg cttacgtccg ataggagact tagtcaaagt aattttaatt tgagccatga
     6121 tgatcccctt tcttatgcta agtcagaaac tgagatgcca cgaagtgcgg caacttcttc
     6181 tgcacgttta agttgtttca atccttcaac agttgcacga acaatgttga ttggagtgtt
     6241 tgaaccaaga gattttgaag taatatcagc aacacctgct aattcgatga cggcacgaac
     6301 tgcaccacca gcagcaactc cagaaccttc tacagctggt ttcaataata ctttagctcc
     6361 accgaagtta gtgtaaactt cgtgagggat tgttgtacca accattggta cttcgatcat
     6421 gtttttctta gcagcttcaa ctgctttacg gatagcttct ggaacttctt gagctttacc
     6481 agtaccaaat ccaacacgac catttccatc accaacaact acaagagctg caaagcgaag
     6541 acgacgtcca cctttaacaa cttttgtaac gcggttaatc gcaacaacgc gttcttcaag
     6601 ttcaactgca ttatctttaa atgccattat tttgtgtcct ccctattaga atttcaatcc
     6661 gttttcacga gctgcatcag ccaaggcttt aacacgtccg tgatagagat atccaccgcg
     6721 gtcaaacacc acttcagaaa tacctttagc cactgcacgt tcagcaacaa gtttgccgac
     6781 tacaacggct tgttctgttt ttgttccttt agaaacgtct ttatcaagag ttgatgcact
     6841 tgcgagcgtt acacccgcta cgtcatcaat aacttgagcg tagatgcctg tattagaacg
     6901 gaatacgttc aaacgtgggc gatcagcagt tccagagagt ttaccgcgga cgcgacggtg
     6961 gcgtttttgg cggattttgt ttttatctgg tttcgaaatc acaattttca cctcttaatt
     7021 ttaatcaatt tgtctcattg acaagttgtc gattgaactt atcgagcatg ttaaggtgca
     7081 atacttccca tacccgacta agaacattat ttacctgttt taccttcttt aaggcgtacg
     7141 tattcaccaa cgtaacggat ccctttgcct ttgtaaggct ctggtgaacg caagctacgg
     7201 atgtaagcag ctgtttgacc aacaacttct ttgttgattc cttcaactga gattgaagtt
     7261 gggttagcaa cagtgaaagt aattccttct ggagcttcaa cttcgtcttg gtgagactta
     7321 cctactgaaa ggacaagttt agtaccttga agttgagcac ggtaaccgac acccttcatt
     7381 tcaagatctt ttttgaaacc ttcagaaaca cctacaacca tgttattcaa gttagcacgg
     7441 gttgtcccat ggattgtttt catttctttt gagtcgttag gacgtacaac tgtgatttca
     7501 gtcccttcaa ctttgatttc aatatttttg ttgaactcac gagtgagttc gcctttaggg
     7561 cctttaacag taataacatt gttgttattt gttaattcaa cgcctgcagg catagtaatt
     7621 actttattac caatacgtga catgtttatt ttctcctgtt aaattgtcaa gccgcatagc
     7681 gactagtttt cacgggggtt tgatagaatg atatacttca atttatattt caaaattgaa
     7741 cacgagctgt ggtctgtgtg aaaaagataa atcttccttg agtgtaaaca cgctacgtca
     7801 gatttcctat tttcactttg tccacgacgc tcttagtatc ttaaattacc aaacgtaagc
     7861 gatcacttct ccaccaacat tcttttggcg agcttctttg tcagtcaaaa gaccttctga
     7921 tgttgaaatg attgcaattc caagtccgtt aagaacttta ggcatgtcat cacgttttgc
     7981 gtaaacgcga agacctggtt ttgaaatacg ttttaagtta gtgataacac gctcaccatt
     8041 ttttccgtat tttaagaaca cacgaatgat gccttgttta tcatcttcga taacttcaac
     8101 attttttaca aaaccttcac gtttaagaat ctcagcaatc ccttttttaa tgtttgaagc
     8161 aggtacttct aacacttcgt gttttacttg attagcatta cggatacgtg ttaaaaagtc
     8221 tgcaattggg tcagtcataa ccatttttta tattctcctc ttactagcag tttgatgcta
     8281 tcacttacta gttaatgttg tccttaaagg actttggtat cagcttatgc tcacaccgtt
     8341 ttaattaagc acaagactta atctgaagaa caaattaagt tttgtgtcat atttttacca
     8401 agaagctttg acaacacctg gaatttgacc tttgtaagcc aattcacgga agcaaacacg
     8461 acaaagttta aacttgcggt aaactgaatg tggacgtcca catttttcac agcgagtata
     8521 agcttgtgta gagtgttttg caggacgttt gttcttagca atcatagatt ttttagccaa
     8581 tttatttacc ccctattatt ttgcaaaagg cattccaagg cccttaagca attcacgtga
     8641 ttcttcgtca gtatttgcag tagtgacgat tacaatatca agaccacgta ctttatcaac
     8701 atcatcaaag ctgatttctg ggaagataag ttgttctttc acaccgagag tgtagtttcc
     8761 acgtccatca aacgattttg tcggaacgcc atggaagtca cgtacacgag gaagtgaaac
     8821 gctaaccaat ttgtctagga attcgtacat acgttcgcca cggagggtaa cttttgcacc
     8881 gatcgctaca ccttcacgaa gacggaagcc agcgattgat ttcttagctt tagtaataag
     8941 tggtttttga cctgagataa gtgctaattc agctgcagct ttctctaggt tttttgcgtt
     9001 ggatacagca tcaccaacac ccatattgag aacaattttc tcaacttttg gcacagccat
     9061 aactgatgtg taattgaatt tctctgtcaa cgcaggaatt acttcgttag tatatttttc
     9121 ttttaaacga tttgccatta tgcttctcct ttccttcgtg attaatcaag cacttcgcct
     9181 gattttttgc tgtaacgtac ttttttaccg tcaacaactt tataaccaac acgtccagct
     9241 acaccatttt tatctaatac ttgaacatta gagacatgga taggtgcttc tttttcgacg
     9301 atagctcctt gaggattttc agtgttaggt ttttggtgtt ttttaatcat tccaacacct
     9361 tcaacaataa ctttgttaac ttttgggagt gctttaagaa ctacagcttc agtgcctttg
     9421 tccttgccag caattacgcg aactttgtcg ccttttttta caaacattct ggtttctcct
     9481 attatttctt acgccccgat gggcacccta ggaaaaccta ggggactacg tttgttaatc
     9541 tgagattaaa gtacttctgg tgcaagtgat acgatcttca tgtagccacc ctcacgcaat
     9601 tcgcgtgcaa ctgggccaaa gatacgagtt ccgcgaggag ttttatcatc acggatgatt
     9661 acagcagcat tgtcgtcaaa tttgatgtat gaaccgtctg gacggcgtgc accagttttt
     9721 gtacgaacga taacagcttt aaccacatca ccttttttaa ctgctccacc aggagtagct
     9781 tgttttacag aagcaacgat tacgtcaccg atgttagcga atttacgtcc tgaaccacca
     9841 agtactttga tagtcaagat ctcacgagca ccgctattat cagcaacttt caagcgagtt
     9901 tcttgttgaa tcatttcaat tttctccttt tagtttgatt agataataac agctttttcc
     9961 actacttcca caagacggaa acgttttgta gctgaaagtg ggcgagtttc catgatacga
    10021 acgatatcgc cttctttagc aacgttgttt tcatcatgtg ctttatattt tttagaatag
    10081 ttgatacgtt taccatagac tgggtggtta cgtttagttt caactacaac tgtgattgtt
    10141 ttgtccatct tgtcagacac tacgcgtccg taaagagttt tacgttgatt acgttccatt
    10201 tagaatttct cctttcccaa tctattattt catttctgat tgcacagttt taacacgtgc
    10261 aatttgtttc ttaacttcgt caaggcgagc agtcttttca agttgacctg ctgcagcttg
    10321 gaaacgaaga tcaaacaatt cttttttgag ttcgttttct ttcttagcaa gttcttcttg
    10381 agacaatcca cgaagctctt taacaaaatc tttaatttct tgaagtttca tgtcttctcc
    10441 ttattctgct tcacgtttta cgaatttgca cttaactggt aatttgtggc tagcaagacg
    10501 taatgcttcg cgagcaattt cttcagaaac accagcaatt tcaaacatca ctttaccacg
    10561 tttaactggt gctacccaac cttcaggtgc ccctttacca gaacccatac gtacaccgat
    10621 agcttttgca gtgtatgatt tgtgtgggaa gattttaatc caaactttac caccacgttt
    10681 catgtaacga gtcatcgcaa tacgggcagc ttcgatttga cggtttgtaa tccagtggct
    10741 agttgtggct tgaagtccgt attcaccgaa tgaaacttct ttaccacctt tagcctcacc
    10801 gcgcattttt ccacggaatt cgcgacggtg tttaacacgt ttaggtacta acatttgtta
    10861 tttgcctcct ttagtgtttt tacgagctgg aagaacttct ccacggtaaa tccaaacttt
    10921 aacgccaagt ttaccataag ttgtgtcagc ttcttcccaa gcatagtcga tatcagcgcg
    10981 aagcgtgtga agtggaacag ttccttctga ataaccttca gcacgagcga tatcagcacc
    11041 gttcaaacga ccagaaactt gagttttaat ccctttagct cctgcacgca ttgtacgttg
    11101 gattgcttgt ttttgagcac gacggaaagc aacacgttgc tcaagttgac gagcaatgtt
    11161 ttcaccaaca aggtgagcat ctaaatcagg ttgtttgatt tcgatgatgt tgatgtgtac
    11221 ttgttttcca gttaatttgt taagttgacc acgaagagcg tcaacgtttg cgccaccttt
    11281 accgataacc atacctggtt tagcagtgtg aagtgaaaca ataactttgt ttactgcacg
    11341 ttcaatttca atagttgaaa ctgatgcgtc agctaattct ttattaatga atttacggat
    11401 tgcaagatct tcatgaaggt aatccgcgta ttctttttca gcataccatt tcgcatccca
    11461 gtcacggatg attccgacac gcataccaat tggatgtact ttttgaccca cgattttacc
    11521 tccttatttt tctgatacaa ctacagttac gtgagttgta cgtttgttga ttggtgaagc
    11581 tgaacctttc gcacgtggac ggaaacgttt cattgttggt ccttcgttag cgaatgtttc
    11641 agatactacc aagtttgctt tttccaaacc aaagttgttt tctgcgttag caattgctga
    11701 gttaagagtt ttctcaataa cacgagctgc tttgtttgga gtgaatttta agattgcgat
    11761 tgcgtcagca actttcttac cacggataag atcaagtact aaacgtgttt tacgaggtga
    11821 aacacgcact gtacgagcca ttgctttagc tgaagtaatt tctgccattg tgtcctcccc
    11881 ctattaacga cgtgttttct tgtcgtcagc tgcgtgacct ttgtaagtac gcgttggtgc
    11941 aaattcacca agtttgtgac ctaccatgtc ttcttggatg taaacaggta catgtttacg
    12001 tccgtcataa actgcgattg tatatccgat gaaacttggg aaaatcgttg aacgacgtga
    12061 ccaagttttg attacttttt tcttttcgtc gtttgcttga gcttcaactt ttttcatcaa
    12121 atgctcatcg acgaaaggtc cttttttaag actacgtccc attttgtagt tttctccttt
    12181 aaataatgta ccacagcggc ttgagttcaa gagcaagact ccaaaactct accgagttgg
    12241 cggaataaat agcaaagcta ttgtaacgct atttcagcaa gttttaagca acttactaag
    12301 attatttttc gttacgacga cgaacgataa gtttgtctga tttagctttc ttgttacgag
    12361 ttttaagacc aagcgctggt ttaccccatg gagttgatgg cgctttacgt ccaactggtg
    12421 ctttaccttc accaccaccg tgtgggtgat cgttagggtt cattacagaa ccacgaactg
    12481 ttgggcggat acctttccaa cggctacgtc ctgccttacc aatgttaaca agtgattgtt
    12541 gttcgttacc aacagtaccg atagttgcac ggcatgtacc aagaatcata cgaacttcgc
    12601 ctgattgaag acgaacaaga acgtatttac cttcttgacc aagtacttga gcagaagctc
    12661 cagctgcacg aacaagttct ccacctttac caggtttcaa ctcaatattg tgaacaactg
    12721 taccgacagg aatgtttgct aatggaagtg cgttaccaac tttgatatct gcatctggac
    12781 cagaaacaat acgttgacct acttcaagac ctttaggtgc aatgatgtaa gctttcacac
    12841 cgtcagtgta atgtacaagt gcgatgtttg cagtacggtt tggatcatat tcgattgttt
    12901 taacaactgc ttcaacgcca tctttgttac gtttgaagtc gatcaaacgg taatgacgtt
    12961 tgtgtccacc accttggtga cgaactgtga tgcgaccatt gttgttacga ccagctttgc
    13021 tcttaagaga aacaagcaat gatttctcag gcgtgcttgt tgtgatttcc gcgaaatcca
    13081 aagaagtcat gttacgacgg ccatttgtcg ttggtttata aactttaata cccacgttat
    13141 ttcctcctta gattattcag cttcagctgc gaacaactcg attgctttag aatcagctgt
    13201 aagagtgatg atagcttttt tagtttttga agtgaaacct gtgtaacgac caacgcgttt
    13261 tgcttttggt ttaacgttaa cagtgtttac acttgcaact ttaactccgt caaaagcagc
    13321 ttcaacagct tgtttgatca aaagtttgtg tgcacgagta tcaacttcga aagtgtattt
    13381 gcctgcttca agagcaatca ttgacttctc agtgataact ggttttttga ttacgtcgta
    13441 caaattcatt atgcaagaac ctcctcaatt gtagagattg cttctttagt aacaagaagt
    13501 ttgtctgcgt tcacgatatc aagaacactt gcagttgctg cagttgcaac agttacgttt
    13561 ggaaggttac gtgcagaaag tgctgcaaat tcatttcctt cttcaacaag aacaagtact
    13621 tttgtatcaa tgctaagagc tgaaagcact tttgcaaatt cagcagtttt tggtgctgca
    13681 aatgaaaggc cttctacagc tacaaattta tcttcagcaa cttttgctga gtaaactgat
    13741 ttcaacgcaa ggcgacgaac tttttgtgga agtttgtatc cgtatgaacg gggagttggt
    13801 ccaaagacaa caccaccacc acgccattgt ggtgagcgga tagaaccttg acgagcgcgt
    13861 ccagttcctt tttgacgcca tggtttacgt ccaccacctg atactgctga acggttttta
    13921 accgcatgag taccttggcg aaggctagcg cgttggctaa ttacaacatc aaaaacaact
    13981 gattcgtttg gttcgatacc gaagatagcg tcgtttaatt caactgagct aacttcttta
    14041 ccagtttggt caaatagttt tacgtttgcc attttaactg ttttctcctt tcttattatt
    14101 tagcagcttt aactgctgac ttgatagtga taagagattt cttagcacct ggtacgttac
    14161 ctttaataag gataacgttc ttttctggga taacttgtac aatttcaagg ttttgaactg
    14221 ttacacggtt accacccata cgtcctgcca agcgtttgtt tttgaaaacg cggttaggcg
    14281 caacaggtcc catagaacct gggcgacgat ggtaacgaga accgtgagcc ataggaccac
    14341 gtgattgacc atggcgtttg ataacacctt ggaaaccttt accttttgat gtccctgtga
    14401 cgtcaacaac atcaccagct tcaaattgtt ctacagataa ttctgcacca acttctaagc
    14461 cttcaatgtt tttgaattca cgaatgaagc gcttaggagc tgtgtttgct tttgcaacat
    14521 ggcctttggc aggtttgtta ctcaagactt cacgtttgtc atcaaaacca acctgaactg
    14581 cttcataacc gtctgtttca acagttttaa cttgaagcac aacgtttgga gttgcttcaa
    14641 tgacagtaac agggatgaat tcgcctgatt cagtgaagat ttgagtcatt cccacttttt
    14701 tccctaagat tccttttgtc atgagaaaat atttcctttt cttaataata tttcaaaaag
    14761 ttttttatga gcgttttttg tgctcaaaaa agttttttac gagcgttttt tgtgctcata
    14821 gcaagataca aagagcgtca aactcaaaat aaaaatagaa aatctaacac aaaaacttct
    14881 gtttcgagga agatttatct ttttcatgta gagtttagct cgtgttcaag ttccatcaaa
    14941 cactaactgt acttgcaaaa tctcaccgat taaagtttga tttctacgtt gacaccactt
    15001 ggaagatcaa gtttcatcaa agcatcaaca gttttttgtg ttggattgat gatgtctacc
    15061 aaacgtttgt gtgtacgcat ttcaaattgt tcgcgagaat ctttgtattt gtgagtcgca
    15121 cgaataattg tgtaaagact gcgttcagtt ggaagtggaa ctggtccagc aactgtagca
    15181 cctgtacgtg ttgcagtttc aacgattttt tctgccgctg tatcaagtgt acggtgttcg
    15241 tacgctttca aacggatacg gatttttttg tttgccatct tttctcctct cgtctattta
    15301 cgataatagg ctagctcctc aagaaaaccg acacctgttg cgtggcaatg caaccgagcg
    15361 tgtcgcaacc tcttgtatca ttgctaaagc tgtattttta cagcaccaca atataataac
    15421 agaatcattt agtcattgca agctttttag ggcatttttt caaaaaaact accttcctaa
    15481 tgaaaggtaa tttcttggta ctttttaaat tgtttagaga gaataaacca ccgactggta
    15541 ttatctaaca ctgtcgccat ccagacccct atgagtccat attgccaaac cacaccaatc
    15601 acataaccaa ggccaatgcg aatcacccac attcctatgg ttgttgcata gaagggaagc
    15661 tttgcttttc ccaaaccctg ccagacggct gtataaacta aagtgcctgc cgttgcggga
    15721 gctcctagta aagaaaaaag taaaacaacc atggcggacc tttgagcatc agtattctga
    15781 gtaaatagcg gcaagagact aggacctagc agataggtca aggctcccat aaccagcatc
    15841 atgagggtgg ataaaataaa agcttctcta ataatatacc ttatctcagt caccttaccg
    15901 ccccccagtt gcctggccac tagaataatt gttgccgttg ccatggctaa gccaggcatg
    15961 taattaaact gagtcaaggt ttctccaata gcattacctg ccaaggccgt tgtcccaaaa
    16021 cgaacaacaa tgccaataat taggacatct cctgctctca tcatcaaacg ttcaccagca
    16081 gcaggtagtg ataaatcaaa aataattttg tccaaaggtc tcatcaatcg tttcgcaacc
    16141 tgtttaatag gaataaactg acaaagtaaa aacacaccca ctaaacgaga taaaaccgtc
    16201 gcccaagcaa caccaagaag accaaatccc catacataga tagacaaggc agaaaaaatg
    16261 gcattgagta cgtttattaa taagctcact tgcataggaa tcttaggata cccttgagct
    16321 cgaacaatag ctcctaagct agttaaaagt cctagactaa caatcatacc gccgacaatg
    16381 gatagatatt gccctccaac caatgttaca gaagcttcag ctcctagcca ttctaacacc
    16441 tgatgatgtc caacaactga taacaaccct aagccgaccg aaaggaggag tgttacttgc
    16501 aagacacctg ccatatagtt taattgtttg ttctgattat tttctccaat acttcgagca
    16561 atcagactag atacagcggc tcccagcgcg ataaagaggg actgataaat actgataatg
    16621 ttgttagcta tggagacacc agagactgct acaagtccaa tttgagccac caggtaatta
    16681 tcaaccattc ccattaacat ctgtaaaata ttttctatca tagaaggcag agctaaagag
    16741 aaaatttttc ttctattata tatcatttat gtcccctaat aaaaaattct tgatcaaacg
    16801 atttttttaa acacagtcac tggactcatt cagttatttt gttccattaa tgaattcata
    16861 aagtctacct taatagcaga gtcccaagat acacgacact tagtgttaca gtaacaattg
    16921 accacatgcc aatccttaac atttacctaa cgtttataac taagaagacg aagaacaaaa
    16981 ggactccaaa cgaatttttt ctattatata atatattctt catttagcaa ctttcaatgt
    17041 atcaaaatag cactctcgag tcaaaaatgt tttctgatac tcgagagtgc tattttattt
    17101 ggaatcaagt ttaagcaact taggcttatc tcatatttaa tacatttgta tgtttagctg
    17161 atgaaatcta agaccttgcg cccttggatt aaaccacgtt ccatttcatc aaagacttct
    17221 ggagcagtgt caactggaac tttttcgaca accggagcaa ccagaccttc tgcaccaaag
    17281 gcaaaggctt cttccaagtc tttacgtgtc cctacaagtg atccgaccac tttgatacca
    17341 tctaaaacag tttttacgat agacagttcc atgtattctg atggaagacc tacggctaca
    17401 actgttccac cggcacggac actatcaatt gcttggttaa aagcaacttt agaaacagcc
    17461 gttaccacaa caccatgtgc tccaccggtt ttttcttgaa tatagcctgg aacatcttca
    17521 atttctttgc cgttaactaa aatatctgcg ccaacttctt tagctaactc aagtttatca
    17581 ttattaatgt ccactgcgac aacatgtgca ttaaagactt ttttagcgta ttgaacagcc
    17641 agatttccaa ggccacctgc cccaaagata acaatccatt ggcctggagc agcacctgcc
    17701 tctttaatag ctttataagt tgttacacca gcacaagtaa tggaagaagc ttgagccggg
    17761 tctaaacctt ctggaacttt aactgcataa tcagctgtta ctactgcata ttcactcatt
    17821 cctccatcaa cactgtatcc agcattttta acactgcgac aaagtgtctc acgtcctgta
    17881 gtacagtatt cgcaatgacc acatccttca aagaaccatg caatagagac acgatcacca
    17941 acctttaagg atgttacgcc ttctccaatt tcttctacta taccaatacc ttcgtgcccc
    18001 aaaatacgtc ctggtacctg accaaaatcg ccatgtgcaa cgtgtaaatc agtatgacaa
    18061 acgccacagt attctacttt aacaagcgct tcaccatgac caacatttgg aagatcatgc
    18121 tcaacaactt cgacacctgt actagcttga ttaacaacta cggctttcat atcagtcctc
    18181 catctaataa cgacttattt gtaatcggtt acaaataaat tgtacatctt ttcacaatta
    18241 aagtcaacag aaacctgaaa agtttctgaa acttaactgg ttaatcttat agctgtttgc
    18301 ctatctgcaa aatacttaac tacattttct gacactggat ataaatgata tatttagaaa
    18361 ataaaatgat ttcttatgac tttaatcata agaaatcatt tcctggtatc aacattaaaa
    18421 atcacttacg tcgtcctgga cgttcagcat aaccatagta agcatcttca ataatttctt
    18481 gcatgtgatc aaccattgga agacgtgggt tagcaggtga acattggtct tcataagcaa
    18541 ggtaagccaa ttcacgagaa tgttctttcc attcattttc gtcgatacct tgagctttga
    18601 agttcatttg aataccaact cggcaaccca gatcataaac agctttcgca taagattcca
    18661 ctgcttcttc tggtgtagaa gctggaagcc ctaacaattt cgcaatgtct tggtattttt
    18721 catccgcacg gtagtaatta tacttaggcc atgtcgccgt tttagctgga cgagttccat
    18781 tatagcggat aacatacggc aaaagaattg catttgtacg tccgtgtacg gtatggaatt
    18841 gtgcgccaat tttatgcgcc attgagtgag aaatacctaa gaatgcattg gcgaaagcca
    18901 tacctgccat agttgacgca ttgtgcatct tttcacgtgc ttcaaaatcg gctattttaa
    18961 ctgatttttc aagattatca aaaacaattt taatggcttg aagagctaaa ccatccgtaa
    19021 agtcattggc catttgtgac acgtaagctt cggttgcgtg tgtcaaaacg tccataccag
    19081 tatcagcagc aataaagcct ggaacagtca ataccaaagc tgggtcaaca atggctacag
    19141 ttggtgttaa tgagtaatca gcgattggat atttacgatt atttgctttg tcagagataa
    19201 cggcaaatgg tgtcacctct gaacctgttc cagaagttgt tgggatagca acaaattttg
    19261 ttttcttacc aagttctggg aatttgaacg cacgtttgcg gatatccatg aatttttgaa
    19321 cgaggtcatg gaaatcaact tctggttgct cgtagaagag ccacataact ttggctgcat
    19381 ccataggaga tcccccgcca agggcaataa tggtgtctgg tttgaaggta cgcattaatt
    19441 cagtaccttt cataacagtt gtaatgtctg gatctggttc tacttcagca aagatctgat
    19501 aaacaacttt attgcgacga agatcaagtt gttcaatgat acgatccaag aaaccaagct
    19561 caaccatagc gtgatctgta acaatcatga cacgttcaac gtcacgacat ttttgcaaat
    19621 attgaattga atcacgttcg aagtatgttt ttgaaggaac tttaaaccat tgcatattat
    19681 ttctacgtct tcctactttt ttgatgttca agagatttat agcactaaca ttatcaccaa
    19741 ctgcgttacg tccatacgaa ccacaaccaa gagtcaatga tggcaagaaa gcattgtaaa
    19801 catccccgat accaccaaat gtagaaggtg aattccagat gacgcggata gcacggattc
    19861 tagttccaaa ttcttttgcc aactctgcat ctgctgtatg aatggcagct gagtgaccga
    19921 gtccattaaa ttcaaccatt tgacgagctt tttcaacacc gtcttcacgt gattcagatt
    19981 tcaaaacagc aatgactgga gataattttt cacgtgttaa aggctcattt tctgaaactt
    20041 ctttacattc tgcagcaaga atattggttc cttctggaac agtaaatcca gcttgttctg
    20101 caatccaagt agctggtttt cctacaatat ttggatttaa ttttgcacca gcacagtttt
    20161 tgctatttgc tttggcacca aaacagaatt cttcaagaag ggctttttct tttttattta
    20221 caaaataagt atggtaagat ttgaattctg ctacaaaatc gtcgtagatt tctttatcga
    20281 tgataacagc ttgttcagag gcacagacca taccattatc aaatgattta gacatcacaa
    20341 tatcatgagc ggcttgacgg atattagctg atttttcaac ataagctgga acgttaccag
    20401 cacctacccc aagggcaggt ttcccacatg agtatgccgc tttaaccatc gcatttccac
    20461 ctgtcgcaag gatagtggca atgccgtcat gattcatcaa agcatttgtt gcttcaagtg
    20521 atggtgtttc aacccactgc acacaatttt caggagcacc agcggcaata gcagcatcac
    20581 gaacaatacg agcggcatgt gctgatgatt cttgtgctga tgggtgaaag gcaaaaataa
    20641 ttggattacg tgtttttaac gagatcaaag atttaaagat agctgttgaa gttgggttag
    20701 ttgtgggtgt aatcccacag ataacaccca ccggctcagc aattaatgtc aaacctgtca
    20761 catcatcttc ttcaataatt cctactgttt tttgatggcg catgttatta accacatgct
    20821 cacaagcaaa tagatttttt gttgctttat cttcaaagac accgcgacct gtttcttcat
    20881 aagcatgttt agcaagttca ccgtgagcat ccaaggcagc aacagaagct ttggctacga
    20941 tataatcaac ttgttcttgg tcaagcttac gcatctcttc aagagcagct aaaccttttt
    21001 gaacaagagc attaattgtc acagaaacag aggttgtttc aacagtatta tgtccttcag
    21061 tcatttgaga ctcctttatc ttgttaaaag tttcacaatt ttgtttacaa aattattata
    21121 gcactttttg aaattttgta aatcatttca caataaattt gtgaagtttt tttcaaatta
    21181 tttctgaaat c
//
LOCUS       DATWVB010000028        20733 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.028, whole genome shotgun sequence.
ACCESSION   DATWVB010000028 DATWVB010000000
VERSION     DATWVB010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20733
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.028"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(119..1255)
                     /gene="dnaJ"
                     /locus_tag="VCX65_001208"
     CDS             complement(119..1255)
                     /gene="dnaJ"
                     /locus_tag="VCX65_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEP5053671.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            complement(1536..3362)
                     /gene="dnaK"
                     /locus_tag="VCX65_001209"
     CDS             complement(1536..3362)
                     /gene="dnaK"
                     /locus_tag="VCX65_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEP5053672.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAVAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            complement(3543..4115)
                     /gene="grpE"
                     /locus_tag="VCX65_001210"
     CDS             complement(3543..4115)
                     /gene="grpE"
                     /locus_tag="VCX65_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEP5053673.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(4118..5152)
                     /gene="hrcA"
                     /locus_tag="VCX65_001211"
     CDS             complement(4118..5152)
                     /gene="hrcA"
                     /locus_tag="VCX65_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEP5053674.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFKLE
                     DMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            complement(5287..5856)
                     /locus_tag="VCX65_001212"
     CDS             complement(5287..5856)
                     /locus_tag="VCX65_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEP5053675.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQAA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            complement(5853..6596)
                     /locus_tag="VCX65_001213"
     CDS             complement(5853..6596)
                     /locus_tag="VCX65_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEP5053676.1"
                     /translation="MKHNHFKLLLQTLVVLLFVGGIYLFIKPEKQATKTPSSQQASSQ
                     KVVKNSKESTGLPKVSPKDWELILVNRDHMTEELSPELVDINGISVDKRIEQATSDFL
                     AAAQAIDPQEHLISGYRSVAYQAELYQSYIKKEMANDPTLTQEAAEALVQTYLQPPGA
                     SEHHTGLAIDMSTVDTLNASDPSVSKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMAQHNLTLEEYIAALKEKR"
     gene            complement(6586..7293)
                     /locus_tag="VCX65_001214"
     CDS             complement(6586..7293)
                     /locus_tag="VCX65_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEP5053677.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEFEDGQFTIKTIGDM
                     SYRYRGREIIEAMSDEA"
     gene            complement(7685..7924)
                     /locus_tag="VCX65_001215"
     CDS             complement(7685..7924)
                     /locus_tag="VCX65_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEP5053678.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            complement(8143..8358)
                     /locus_tag="VCX65_001216"
     CDS             complement(8143..8358)
                     /locus_tag="VCX65_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053679.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTVYKKTIIYAKI
                     RLTGIALEPSGVSDVYLMNYHVCLHYY"
     gene            complement(8355..9794)
                     /gene="gatB"
                     /locus_tag="VCX65_001217"
     CDS             complement(8355..9794)
                     /gene="gatB"
                     /locus_tag="VCX65_001217"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEP5053680.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKALSDFFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIRLTPDNLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLRD"
     gene            complement(9794..11260)
                     /gene="gatA"
                     /locus_tag="VCX65_001218"
     CDS             complement(9794..11260)
                     /gene="gatA"
                     /locus_tag="VCX65_001218"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEP5053681.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFI
                     TVSEEAALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            complement(11260..11562)
                     /gene="gatC"
                     /locus_tag="VCX65_001219"
     CDS             complement(11260..11562)
                     /gene="gatC"
                     /locus_tag="VCX65_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEP5053682.1"
                     /translation="MKISEEEVRHVAKLSKLSFLESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDIAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            complement(11794..12112)
                     /locus_tag="VCX65_001220"
                     /pseudo
     CDS             complement(11794..12112)
                     /locus_tag="VCX65_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991537.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dikinase"
     gene            complement(12556..13110)
                     /locus_tag="VCX65_001221"
     CDS             complement(12556..13110)
                     /locus_tag="VCX65_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEP5053683.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDPWHPESKLFAAHNIKGTTGRHLYGPLAEVYSYMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            complement(13257..14039)
                     /gene="codY"
                     /locus_tag="VCX65_001222"
     CDS             complement(13257..14039)
                     /gene="codY"
                     /locus_tag="VCX65_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEP5053684.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASIIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            complement(14257..15471)
                     /locus_tag="VCX65_001223"
     CDS             complement(14257..15471)
                     /locus_tag="VCX65_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEP5053685.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISISLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            15702..16154
                     /locus_tag="VCX65_001224"
     CDS             15702..16154
                     /locus_tag="VCX65_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEP5053686.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDDFEKQAQIAGITNIKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            complement(16277..17665)
                     /locus_tag="VCX65_001225"
     CDS             complement(16277..17665)
                     /locus_tag="VCX65_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP5053687.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDIEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            17737..18702
                     /locus_tag="VCX65_001226"
     CDS             17737..18702
                     /locus_tag="VCX65_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEP5053688.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQDIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVVLVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(19051..19755)
                     /locus_tag="VCX65_001227"
     CDS             complement(19051..19755)
                     /locus_tag="VCX65_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053689.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYLLGNVFLFSKRELK"
     gene            complement(19768..20670)
                     /locus_tag="VCX65_001228"
     CDS             complement(19768..20670)
                     /locus_tag="VCX65_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053690.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
BASE COUNT         6303 a         4386 c         3586 g         6458 t
ORIGIN      
        1 ccattttgac aagagaaaaa aacgatatct ataaaagaaa acgttttctc taactgtttt
       61 gacgtaaaaa aacgtataac ttcgggaaaa ttatcctgag attatacgtt tgacatcttt
      121 aaatatcctc taaggcatct ttcactttat caaaaaaacc ttttttcttt ggatgtaaca
      181 ttttttcacc actcgcttct gcaaatgctt gcaaggcttc cctttgagcg tcattgagtt
      241 tggttggggt cacaatatta acggtaacat gttgatcccc ttgacctcca ccacggagtt
      301 ttggtgctcc tttgcctttg aggcggaagg ttttacctgt ttgtgtccca gcagggatag
      361 ccatctcaac atcgccatga accgttggaa tttcaacagt atctcctaag gctgcttgag
      421 taaaagaaat atctaagttg tagtaaatag tggaaccatt gcgttcaaat tgcttacttg
      481 gtaagacatt caaaataaca aataaatcac cataaggtcc gccattaaag ccagcttctc
      541 cttgaccttg taaacggatt tgctgaccag tctctacacc agctggaatc ttaacagaca
      601 ctttatgagc ttgcttttca tgaccagtac cgtgacaggt ttgacagggt tctttaattt
      661 ccttaccact accatgacaa atatcgcagg tgacttgtcg acgcatcata ccaagtggtg
      721 tttgggtgtc aattgtcatt acacctgaac catggcactt acgacaagtt actggagcgg
      781 taccaggttt tgcacctgag cctaaacaag tgccgcaggt tgcttcgcga ttatagctaa
      841 cttctttttc aacaccaaat acagcctctt caaaagataa attaacacga tattgcaaat
      901 cgtcaccttg acgaggggca tttgggtttc ggcttccacc gccaccaaag aagcttgaga
      961 agatatcttc aaaaccacca aagccacctc cgtcaaaacc accaaagccg cctgctccgc
     1021 caccaaagcc gccttgagca cctgcagcgc cgtattgatc ataagcagca cgcttttgtg
     1081 aatcacttaa ggtttcgtaa gcttcttgaa catccttata cttttgctcc gctccagctt
     1141 ctttattgat atctggatga tatttcttag acatttttcg ataagctttt ttgatatcgt
     1201 cctgagaagc gtccttagaa acccccagac gatcgtaata ttctgtattg ttcataatgt
     1261 aagataccaa gccgtaaaac gactcaatga aaaataggaa atccgacaaa gatactctcg
     1321 tatctaggag gtatttctct tttttcgcag agtcgtaggc gtgttcgaat ccgcaaaaga
     1381 gtctttacac gctttagcct gtgttcgaat aatcgaactt gtattccttt cttaaaatat
     1441 tttgacgtca gcatttttac attttattta gccaaaaaca gaggtttggt acaacctctg
     1501 aattcggata ttaatgttac tagataacta aatcattact tttctgtaaa ttcgccatct
     1561 acaacatcat cattatttgc tgaatcatta gcttgtgcac cttctgcacc ttgtgctgct
     1621 tgttgagctg ctacagcttg ctcgtacatt ttaacagcca aagcttgcgc tttttcattt
     1681 aatgcttcaa gtttagcttt catgtcgtca aggttgccag attcttgcgc agcttttaac
     1741 tcgtcaagag ctgattgcgc tgcatcgcgt tctgtatcaa agcctttacc ttcagtttct
     1801 ttgattgttt tttcagtagc aaagatagct tggtcaactt cgtttttaag gtcaacttct
     1861 tctttacgtt tcgcatcggc ttcggcatta gcttcagcgt ctttcatcat gcgatcaatt
     1921 tcttcttcag aaagtccgtc gtttgatttg ataacgatgt gttgttcctt ttgcgtacca
     1981 aggtctttag cttttacaga aacaataccg tttttatcga tatcaaatgt tacttcaatt
     2041 tgtgggattc cacgaggtgc agctgggata tcagtcaatt ggaagcgacc aagagtcttg
     2101 ttatctgctg ccattgggcg ttcaccttga agaacatgga tatcaacagc tggttggttg
     2161 tctgctgctg ttgagaagac ttgtgattta gatgttggga tagtggtgtt gcggtcgatc
     2221 aatttggtga agacaccacc cattgtttca ataccaagtg acaatggtgt tacgtcaaga
     2281 aggacaacgt ctttcacatc cccagtgata acaccacctt ggatagcagc acccatagca
     2341 accacttcat cagggtttac agatttattt ggttctttac cagtttcagc ttttacagct
     2401 tcgacaactg ctgggatacg agttgatcca ccaacaagga taacttcatc aatttctgac
     2461 aatgacaatc ctgcatctga aagggcttga cgaactggag ttttcgtacg ttctacaagg
     2521 tcgcgagtga gatcgtcaaa tttagcacga gataagctca tctccaagtg aagaggaccg
     2581 gcagaaccag cagtgatgaa cggtaatgaa atttgtgttt gtgtcacacc tgaaagatct
     2641 tttttagctt tttcagcagc atctttcaag cgttgaagtg ccatcttatc ttgtgataag
     2701 tcaatgccat tttctttctt aaattcagcc actaagaaat caataatttt ttggtcaaag
     2761 tcgtcaccac caagtttgtt atcacctgct gttgcaagaa cgtcgaagac accatcacct
     2821 aattcaagga ttgatacgtc aaatgtacca ccaccaaggt caaaaactaa gattttttca
     2881 tccttgtcag tcttgtccat accataagca agtgcggctg ctgttggttc gttaacgata
     2941 cgttctactt caagacctgc aattttacca gcgtctttag ttgcctgacg ttgtgcatcg
     3001 ttgaagtaag ctggaacagt aataactgct ttttctactt tttctccaag atagtcttca
     3061 gcataacctt taaggtattg aagaatcatt gctgaaattt cttgaggagt atattcttta
     3121 ccatttgcag aaactttttc agaagttccc attttagatt taatagagat tactgtttct
     3181 gggtttgtca ctgcttgacg ttttgcagca tcacccacga taatttcacc atttttgaat
     3241 gatactactg aaggagttgt acgattgcct tctgggttag caatgatttt tgattcagtc
     3301 ccttcaagaa ctgctactgc tgagtttgtt gtacctaagt caataccaat aattttagac
     3361 atgttaatac ctcttatttt ataatacttt attacttttt atttcaattt atcttagtaa
     3421 gcactcgaat tattttactt ccaattctaa gcaatcacta tagtttaatc agcaagcgaa
     3481 ataacttcta acttgctatc tagtttactg tcattacgga caaaaacgaa aactcattta
     3541 ccttagttat agacaactac catcgctggt cttagcagac gctcgtgcaa tttatatccc
     3601 ttttgaaaga cttctgcaat gctatcggct ggatgttcat catcggctgg gagggtctga
     3661 actgccatat gaaagttgtg gtcaaatgag tcaacttcta cttcttctac gccttcttcc
     3721 tttagtgctt gaataaggct atcacgagtc atttctaaac cttttttaac atcatctgtc
     3781 aacccttcaa cagccaaggc acgttctaga ttgtcaagcg atggtaagat tgcttttgcc
     3841 agatcctgag aacgatagcg ttgaagttgt tgacgttctt cactagagcg acgctgtata
     3901 ttctgcattt ctgcatgagc tcgcaagtat ttattttcaa actcatcagc acgttcgttt
     3961 gcaagttcta actctgattt ttcaggagtt tcttcaataa cttcctcaac tgtctcttca
     4021 gtttcagtgg cttccacttc ttcttgtaaa tcgtcttttt taatttcttc tgacactgag
     4081 tgcctccttt taaataactt attgaatact gccattatca gtggacttca taatggttag
     4141 aatttaggta tcgataataa tcacctaatt tagcagccaa tacctttcca ataatgttta
     4201 ccaaactaac agacctacga taatccatat caataggacc aatcaaactc aggagtccaa
     4261 acccacggta aggaatcaaa aatttgtgag tcaaaactga cacatctgca agtgcggctt
     4321 cttgactatc tgccacttgg acagaagcca tctcaccttc tttcagactt tgcctcaaag
     4381 aaattgctac ttgctgttca ttatccaaaa actgatacgt tgatagatct gaatacgtta
     4441 aagaatttac cttaccagca acaaataccg tttccaaaaa cagctctgaa aaaacataat
     4501 caaatagttg taaaacatta tccgtagtca caaaatactt ttgaacgatc tgaggaattt
     4561 ctgtcctcaa cttataatga atatctatga cactactatc cagcaagcgc tcctctacga
     4621 tagctttaaa tgctatcaag tcacgtgtca aaaagtttct tggaatagca aactgcactg
     4681 tcactggctt agattcatct aaagtcatga ctgctagagc atcatggttg ctaagctgaa
     4741 caacatcaaa ccctgttaaa cgttgacgag ctggctccac atctaaaata acggatgtat
     4801 agcccgtcat ctccgctaaa atgtgactag ctttttgaag catgtcttct aatttgaatg
     4861 cttcaaaatc aaaagttttt atgacatgat aaatatcttg ctcatcaata ctatctagcc
     4921 tgagggagtg ctctacaaaa tacttaaagc cagctggact tggcatccgt ccactagaag
     4981 tgtgcgcttt ttccaacaat cccaacttct ctagttttgc catatcatta cgaatagtgg
     5041 cgctactaga atcaatcgtt ctctgtaaag ctttagaccc tactggttca tgagtttgtg
     5101 taaatagctc aacgattaaa ttcaaaatat cattttgacg ttgtgtaatc acaaaccaac
     5161 cactcccttt cgtttagcac tctatttagt agactgctaa tttataattc tattatactc
     5221 tttatgggac acatgtcaag aaaaaaactc aaaaaaatta gcactctttt ataaagagtg
     5281 ctaatttcag tcatagtttg ttaaatcgtt actttcaatg acctgaatca gtcgcctagc
     5341 ataggtttta tcagtataat gcaaatactt ttgtaaactt ttagctggtg ctttataccc
     5401 tttttctgta gcaagattac gatacaaacg cttatcgact tcttttccct gccgaagcat
     5461 tcgtaaataa tctctaattg cactagcgtc atctttataa atagcatatc tcacgttttg
     5521 gttggtttgt ttaggggact ttagggtaat ggccgcttgt cctggagttg ctttcttgct
     5581 aaaaagatta tgatacttag acgctagtaa tgtttttcca tcatgggttt ccaaaagaat
     5641 ttgagcaatc aaaatagatg gtctaatgcc ataatatttt gccaatggtt taacttcttt
     5701 acccattttt gtaataaatt gtttttggct gtagttcacc cttacttctt tatctgcact
     5761 agctatcctt tggctactca gtaagggaca aacaatcagc aataaaaagc aagctagaag
     5821 cgttaaaaaa tacggaaact ttagtcgttt tctcatcgtt tctcctttaa agcagcaatg
     5881 tactcttcca acgttaggtt gtgctgagcc atataacgag cagacgcctt gcctacatag
     5941 cggtaatgcc aatcctcata atcaacccct gtactagtct tttttccttc tggaaagcgc
     6001 aagacaaacc cataatcagg tgcaattttt tgaactgctt tagataccga tgggtcactg
     6061 gcatttaaag tatctacagt gctcatgtca atagcaagac cagtgtgatg ttcactagcc
     6121 cctggcggct gtaaataggt ttgcaccaaa gcctccgcag cttcttgtgt caatgttgga
     6181 tcgttagcca tctctttttt aatataagat tggtaaagct ctgcttggta agctacggag
     6241 cgatagcctg aaataaggtg ctcttgtggg tcaatagcct gagctgccgc taaaaaatca
     6301 ctagtggctt gctcaatgcg tttatccaca gaaataccat taatgtcaac taattctggg
     6361 ctcaattcct cagtcatatg gtcccgattc actaaaatca attcccaatc ttttggagag
     6421 actttaggaa gccctgtgga ctctttgcta tttttgacca ctttttgact gcttgcctgt
     6481 tgacttgaag gcgtcttggt ggcctgcttc tctggcttaa taaagaggta aatacctccg
     6541 acaaagagca gaacaaccag tgtttgcaat aataatttaa aatgattatg cttcatctga
     6601 cattgcttct attatttcac ggccacggta gcgataactc atatctccaa tggttttgat
     6661 ggtaaattgc ccatcttcaa attcgacaac agtgacactg ccgttatcaa tatattgttt
     6721 ctcacggtca ggatcgatta gccacataaa tgttccaata gtcatcccat ggctaaccac
     6781 aagagcattt ccgccgccag cattttgaat agacaaagca atagcttcaa acccctccca
     6841 aatgcgctta cgaagaactt cccatggttc tgcccaatta gcggtatcta cttccacgat
     6901 gctttctgcc agttcagaat agggaacatc acgtaggtta tcacgatttt caaaggcttt
     6961 tgttcttgga aggacaccta gaaataattc tgaatcataa gtcccttcta gactcccaaa
     7021 acaccactca cgaatacgat tatctttagt ataaggcaaa aattcgtttt ctgattctct
     7081 taaaataatt tctattgtct gcatggttcg acctgaatca cttgaaaacg cagccttaaa
     7141 tggtatagtt gcatctttta aacctaagcc aagttctcga ataccttctt ctcctttttt
     7201 tgtaagaggt gtgtcactcc aaccctgagc gcgaccaatg gtattaaaca tcgtttttcc
     7261 atgtctggca atatacaacc ttgtttttgt catttcaacc tcctaaactg tcttattaat
     7321 tattatagca tttaaagaaa acacttgcaa aacacttcct gatagctatt tgagatcaaa
     7381 tagaccactg acttattgtc tattttatta aaaataatgc tattgctaca attcaaatca
     7441 tcacataaat ttccaaacga ttacatttgt gcgtttcgct caaatatata taacaacaga
     7501 cccacactac aactaaactg acattacaaa atgatgtcaa aacagtaaca aaatctaact
     7561 atttgtcaag aaaatgatat taaattttca cacaactatc ttataatgag gatgcaacca
     7621 ataaaaagat aagacatttt atgttgcaaa aaaggctgct tggaaacttc catgcagcct
     7681 ttttttaata cctttttcca aaaatagctg aaacaagtac aattacaatt gccgctccca
     7741 aaatggacgg gaaaatagcc atacctgcca actgaattcc ccaatcccca aaaagccttt
     7801 gcccaacagc tgaccctatg agacctgcga taatattagt aaaacaaccc atggactggc
     7861 ttttttcagt cattttacct gctatcatgc cgataaaggc acctacaatt aaagaccata
     7921 tcatcgttaa cacctccttt cttgtaaaat ccttttagaa gaactgctat ccattaaatg
     7981 ttcttaactt tagttgattc ctttaccttc ttctttagta aatgtttccg tgcctgagta
     8041 aaatagaaaa aacaattcct tctattaagg tagatagacc gagaacgact agaagtcttc
     8101 acacactaaa taacttaaca aactttatca cacagctaat cgctaataat agtgtagaca
     8161 aacgtgatag ttcattaaat acacgtcaga aactcctgaa ggttctaaag caatacctgt
     8221 cagtcttatt ttagcataga tgatggtctt tttatagacg gtcactaaca tgacatacaa
     8281 aaaggcagcc tgtgaaagac cgaccgcctt tttttcagag acaaaatact ttaacttatt
     8341 gctatcagca actatcaatc tcgcaatttt tgcaattctt gtgccaataa ttgttgagcg
     8401 acttgtggat tagcttgacc tttggttgcc ttcatcaaga agcctgtgaa agccttatca
     8461 gcattacgtt tgcctgattt gaaatcagcc actgcagctt cattatcagc aaagacttgg
     8521 tgaataattg gtaccaaaac agcgggatca gaaatctgaa caagtcctgc cttttcgacg
     8581 taggcgcgag ctgagccacc gtttttagcc aaatgcacaa agaccttctt agccatttta
     8641 gaagagattg taccatcagc aataatagca atcatttcca ctaagttgtc aggcgtcaat
     8701 ctaatttctt caatggtttt gccttctgca tttaagaatt gggcaacttc cccttgcaac
     8761 cagttagaga cttgcttggc atcgccacca agacttactg cagtttcaaa gaaatctgac
     8821 aaggctttgg tagctgttag ttggctagca tcataagctg agaggccaag ttcctcttcg
     8881 tatttagcac gacgctgagc tgggaattga ggtaattgag cacgcatctc gtcaatccaa
     8941 gcatcatcaa tctcatataa tggcaggtct ggttctggga aataacgata gtccgctgcc
     9001 ccttctttga cccgcatcaa aatagtcccc ttattcgctt cgtcatagcg gcgcgtttct
     9061 tggcgtatca caccacctga acgcaagagt ttggcttgac gttccacctc aaattcaagc
     9121 cctttacgga catttgagaa ggagttcaag tttttcaatt cggtctttgt tccaaattgt
     9181 tcttgcccgt aaggacgaag agaaatattg gcatccacac gcatggagcc ttcttccatc
     9241 ttgacatcag aaatacccgt atactggatg atttctttca gagctgtcaa ataagcatag
     9301 gcttcttcag gagaacgcat gtcggcttct gacacaatct caatcaaagg aactccttgg
     9361 cggttaaggt ccacataaga ataaccatct gtgccatgag tgtttttacc agcatcttct
     9421 tccaagtgtg cgcgttcaat acgaattttc ttagtcgagc cgtcttccaa tttaatctca
     9481 atccatccgt tgtagccaat cggctcgtca aactgtgaaa tttggtaagc tttaggattg
     9541 tctgggtaga aataattttt gcggtcgaaa tgcatctctt tatggatgtc catattgagg
     9601 gcaagcgcag cttttatgcc cgcatcaatc acccctttgt tcatgactgg taagacccct
     9661 gggaaagacc aatcaatcac attcgtgttg gcatttgggt cctcaccaaa gtgagctgac
     9721 gaaggtgaga aaattttgga attggtattt aattccacat ggacttcaag cccaataatg
     9781 gtttcaaaat tcattacttg tcacctccaa aaataatcgg ttgttgcttg tgataatctg
     9841 tcaccgcttc aaaggctgct gccgcctgat agatggtttc ttcagcgtat ttcggaccaa
     9901 ttaattgaag ccctactggc aagccatcga cgaatcctgc tggaatggaa attcctggca
     9961 gaccagccaa gttaactgga atggtcaata agtcggccaa atacatggca acaggatcgt
    10021 ggttgagtgt gtctaagcca aaagcaaccg tcggtgttgt tgggcctaaa ataagatcat
    10081 aatccgcaaa gaccttgtca aaatcttcaa taatcaaggt acgcacttga ccggcctttt
    10141 tgaaataagc gtcataataa cctgatgaca aactaaaggt cccaagcatg atacgacgtt
    10201 taacctcatc accaaagcct tggctacgag tgttaacata gatttcatcc aagtttttag
    10261 catcgtcagc acggaaacca tagcgaatgc catcaaaacg ttgtaagttt gaggacgctt
    10321 ctgacgaagc aataatgtaa tagacagcca caccatattt gctatgtgga agactaactt
    10381 cctcaacagt agctcctaag gcttcaaatt gtttagctgc cgcaagaacc gtttccttaa
    10441 tctcaggatc aatcccttcg ccaagatact ctttaggaag ggcaatcttc atgcctttaa
    10501 tgtcacgacc aatcttagat gtgtagtctg caatgcggac aggcgctgaa gtggcatcct
    10561 tgacatcgct acttgcaatc acatttaata attgggcgtt ttctttaact gtcggagcaa
    10621 aaggtccaat ctgatcaagt gaacttccaa aagcaatgag accatagcga gaaacagtgc
    10681 cataggttgg tttcaaaccg acaacaccat taaatgcagc tggctgccga atagaaccac
    10741 cagtgtctga accaagagat aaacggactt gtcctgaagc gactgctgtt gccgaaccac
    10801 ctgatgagcc accaggtact tttgtgtggt cccaagcatt tttcgttttc ttgaaataag
    10861 aggtttctgt tgaaccaccc atggcaaatt cgtccatgtt ggtttttcca atgacaatca
    10921 tgtctttagc gtaggcattt gctactgatg tggcatcaaa aatcggctcg tagttataca
    10981 acatttttga agcggctgtg gttaggatgc ccttggttga gatattatcc ttaacagcta
    11041 gtggaatacc cgacatgagg ttatcagcat caataccttt ggcatcaatt gccgcagctt
    11101 gtttaagagc agcttcttct gaaacagtga taaacgaccc gacagcctcc tcacgagact
    11161 tgatgtcttc aagtgttttt tgagtcaatt cggttgcgga aatctcctta gctacaagga
    11221 ggtcatgcaa ctcttcaatg gttttatgat taaaagacat taggcatctc ctccgtcatc
    11281 caaaatagca ggtaccttga taaagtgatt ttctttttca ggaacatttt taaagagcaa
    11341 ggcacggtct gttccttcct cagcaatatc ttgacgcatc acatttttct tatctgccat
    11401 ggttgttgta atggcgacac cttcggtgtc aacttcgttc agcaattcaa ccatatcaac
    11461 gattttggat aaggtcgttg caaaggttgt tgtctcactt tctaagaatg ataattttga
    11521 tagcttcgcg acatggcgaa cttcttcttc agaaattttc atgatttctc ccatccaaga
    11581 tgatcagaag tattccaatt ccaaagaaca gctctgctat tctccaaagg tagcggaaaa
    11641 actcctcaca tcgtttttac atagtctcaa ttattatatc acaattgcgc ccatttacca
    11701 taggtgacta atgcaattct agaaagctat acagcaaaaa acttcctgac taaggtcaga
    11761 aaaccttagt caggaagtgt gacaaactaa actctatttg tcttgggtaa gactgtggcc
    11821 tgaagctttg atggcagcct gagcagccgc caagcgagta agcggcactc taaatggcga
    11881 acaagaaacg taggtcaggc cttggctgtg gtaaaagtca atggaagcag gatcgccacc
    11941 atgttcccca caaataccaa gtttcaactc aggcttaacc gaacgggcta aagagacggc
    12001 caatcccttt ctgatcaaag gtctggaacg gctccttatc aaaaataccc ctgtcaacgt
    12061 attcttccaa gtattttcct acaacatcac agaaaaagta acgttctttc aagtcggtaa
    12121 tatgtttacg aaggtagtaa aggggtgctt tattctaatt taccaaatcc tcaacgattg
    12181 tgacaacatg tgatgtgata agcctaagat aaaaatggta cagactctag cattcaagag
    12241 tttgaagctt tatttatatt ctaatgctga aaagactaga gtttgtctaa tggctgtgag
    12301 acgatcctct aaaccaccaa ctcaaatcat ttctcaaaca gctaaaatcc tgtctccttc
    12361 aaaaaaacat gtgttctatc tgacacagtc caaagtttag ttgcctttta gacagcacaa
    12421 gaatcatcag gactaattct gaccagcatg tcacatacct catctaccta acccatacat
    12481 acggtaaaac cacatagagc aatgattacg gttaccaaac tcttagtcac tgaatcaata
    12541 gtttggtagg ctcttttagt aatcgttaat aagcttagca ccaagaacct gctcaaagtg
    12601 agccaaagac cactcataag attcttttgt aaggctagcg acagccgatt taacaatctc
    12661 taattgataa ccaagatgat aagcgtcaat agcagtatgt aagacacaga tatcagataa
    12721 aactcctgtt aacactaatt gagtgatacc tctttctcgt agtctaatat ctaaatcagt
    12781 ccccgaaaaa gctgaataat aacgcttatc aatccaaaaa actctgggat gttgcttcat
    12841 ataactgtaa acttcagcta gtggaccata aagatggcgt ccagtagttc ctttgatatt
    12901 atgtgctgca aataacttac tctcaggatg ccaaggatca ttttgatcat gacaatcaat
    12961 agcaaaaaaa atatagtctc cttgatcaaa tgccgtttta gttacctctg ctattttagt
    13021 ggcaatagcc tgagcagatt tacctgcact taatttacca tcatctgcta caaaatcatt
    13081 tgtgtaatca attgaaatca atgctctcat cactctctcc taaacaggga aacctctccc
    13141 cttatctctt atatatggca ttgtatcagt ttttattaca ggtatcaaga catctatttg
    13201 catctaccat taacagcaaa aaacatctct tttcaagaga tgttgtcttt ttctatttaa
    13261 aattctttta atttagcaaa aataccttcg ttgataactt tgaggtatgt ccctttcata
    13321 ccaagagaac gactttcaat aatccctgca ctttctaatt tacgcagagc attgacaata
    13381 acagaacggg taataccaat acgatcagca ataatagaag ctgtcaatcg tccttcgtta
    13441 ccatctaact ctccaagaat tgctgcaaca gctttcattt ctgaataaga aagcgtatta
    13501 attgccatgt tgaccgctgt ttgtttacgg atggtgtctt ctaagttttc tgtctgaaga
    13561 tttaatagtt gaatccccac aacagtactt gagatctcaa ccaaaatcaa atcatcatca
    13621 ctaaactcat tgtcattacg ccagataatg agtgatccaa ggcgcatccc tccaccataa
    13681 atcggcgcaa tagtcgttag acctcctgga taagtgtctt tagactcaac agggaatata
    13741 gtcaattcat tttcgacaga aaggttagct tctgtatcgt aaactcggct agcagccttt
    13801 acataagtat ctggaaattg tttagcttca aaaaattcct caacacgatc agtgttagtt
    13861 ttatatttca tggcataacc aagcagtgtg ccgccgccat tgataataca agcattgcag
    13921 tcaatgatat ctgctaggcg agatgccatt gtgttatacg gtaattctgt ttctaggcta
    13981 tctacggaac gctgcaaaat agatgtgatt ttacgagttt tttctaataa gttaggcatt
    14041 tttttccttt tcctttgaat tatttgcgct ttcattataa caaagctaac tcgcttttgc
    14101 aaggaattat cagaaaattt tctattctta ctacaattcc aactattgat gccttattat
    14161 cacttcattt aaaggagata agcactagct tgttagagca taggatcaca ttcttttaag
    14221 aaacgctatt tttattaatc aaagatgagc attgcattaa cgtctatact ggtataagac
    14281 acgtgtaatc ttttcttgga catcttctaa ttcttctaca cttggtaggt aaacaatacg
    14341 gaagtgatct ggatctttcc agttaaaacc acgtccatgt accaacatca ctttttcttg
    14401 ctttaataac tgtaagacaa attcttcatc atcatcaata cgatacatct gacgatcaat
    14461 tttcggaaat aaataaagac ctgcttcagg tttaactgcc gataagccag ggatagcatt
    14521 aatagcttca taaataaaat tacgttgctc aaaaatacgc cctcctggca gtaacagtgc
    14581 atcaactgat tgatgacctc ctaaggaagt ttgaacaact tgttgggcta aaacattgga
    14641 gcataaccgc atattggcaa gcatgtttaa cccttcaatg taacctttaa catggtcttt
    14701 aggacctgat aagaccatcc atccaacacg aaaaccagca atacgatgag atttggaaag
    14761 accattcata gatacacaaa aaacatcagg tgccaaactt gcaatagcaa tatgctcttt
    14821 accatccatc accaaacgat catagatttc atcggcaaaa ataatcagct ggtgttctct
    14881 tgccaaagca acgatgtctt ctaaaatctc cttaggataa agggctcctg ttgggttatt
    14941 aggattgatg accacaatag ctttggtgcg actcgtgatt tttgatttga tatcagcaat
    15001 atcaggatac caaccagctt cttcatcaca aagataatgg accgcttttc ctccaccaag
    15061 actcacacaa gccgtccata aaggataatc cggcattggt actaaaactt catcgccatt
    15121 atctagcaaa gcttgaaggg atatggatat caactctgac acgccatttc ccaaataaat
    15181 atcttcaatg tcaacatctg ggaagccctt gagttggcaa tactgcatga tagccttacg
    15241 cgctgaaaaa atccctttac tgtcagaata gccctcactt agcctcgcgt tgacaattaa
    15301 atcacgaatc acttcatctg gtgcttcaaa accaaaagca gcaggattgc cagtatttaa
    15361 acgcagaatt ttttcaccac tcgcaatcat gcgattagct tcatccaaaa caggccctcg
    15421 aatatcatag gcaacatgtt ctaattttga tgatttttca ataattttca tagtctcata
    15481 cacctcgtat tccatattat aaaccaaaat acttaaaata gaaagaattt atccatcaaa
    15541 gcttaggaca gctaatcgtt ttaacacagg tcttatgaga cgataataca gtctttagtt
    15601 tagcaaaaat aatggatcgc tttcaaaatg actcaaaaaa gagtataatg aaaaaaagaa
    15661 taaaagctat tcttgtcaaa ctgttaaagg aggacagttc tatgtcacta aaatataaac
    15721 gtatcctcgt tgctattgat ggctcttatg agtctgaatt agctttcaat aaaggcgtta
    15781 acgtagcact acgtaacgac gctaccttac tactagtaca cgttattgat acccgtgcct
    15841 tgcaaagcgt agctactttt gatacttaca tctatgaaaa attagaacaa gaagctaagg
    15901 atgttttaga tgattttgaa aaacaagcac agatagcagg aattacaaac atcaaacaaa
    15961 ttattgaatt tggcaacccc aaaaacttac tagctcacga tattccagat cgtgagaacg
    16021 ctgatttaat tatggtagga gctactggtc ttaatacctt tgaacgcctc cttattggct
    16081 catcttctga gtacattatg cgacacgcta agattgactt acttgtagtc cgagatagca
    16141 ctaaaacact ctagtctatt acaattttca aacaccaaaa aacaagcagc atctacaacg
    16201 aaattgcttg tttttttgtg ctgagctaag tctagtcaat atctttttat ttcttgatat
    16261 ttaaaagagt aaacctctat ttatcgaatc gttgtagtga tttttgtaat tgtttgtcta
    16321 actctttttt tatggctact tcaggtgcgt gacgctcttg ccaatagtca ggtttttgaa
    16381 ttttatgggt aacggggtca aagtgtgcct tgccatctgg aaaaatttta gccatatttg
    16441 cttcatgtac tgcttcaaat ataggttgtg gatctactcc catcagtaca aaagaaccat
    16501 aagtaaaata aagcaaatcc gctaaggcat caacttgccc aatcaggggc gtttcaacat
    16561 gttttttagc ttgtacctta ttagctgctt ggtcaacagc accatgcaaa tcgaaaatag
    16621 cctgtgtaaa ttgttgttgg tctcccttgc ttgctgcgta aagaaactca acaatttctt
    16681 ctactttaaa gcctgaccta taaccagctt ctgaaatggt ataactacgc ggtgtttcaa
    16741 tagtatctga gtccatcaga cgatgaaaat ctttgacttt attaaaattt tcatcacggc
    16801 ttttaaagct cttctctata tcaaaatgga tgagaccgta gtgagctaag gctttggaaa
    16861 tcccatcatt attattagag tcggtagtga aatgggctcc atcttttacc acagtttcag
    16921 catttcccat agcaataccg ataccaactc ctgataacat ttcaaggtca ttatctgaat
    16981 ctccaaaagc catcacttca gacaagtcaa atccaaacat ctctcccaaa cgttcaattc
    17041 cttttatttt tgattgatca acagagatca gatccaagga ataaggacta cttcttgtaa
    17101 tttttatatg agggaacttc tcttgtattt tcttagtttc agcttgtgac gctaccagaa
    17161 caacctgata aataggctcc cgcataatag ttactaaatt tctaaaactc tgaggcttga
    17221 ttcggcgaat caaatgctta aaactaccct caactgttct tgcccaactt ttgggcacaa
    17281 aactactaat gacttgtcca aatgggctag tccccatatc aataatacgc gatcctgcta
    17341 atccagaagc tgttccaaga gaaatttctc gctttttttc gttggcatag cgaatcactt
    17401 tgtaaatcat cgactttggc aattgattct gatataagac cttatctctt gttaagatat
    17461 attgcccatt gtaagtaacg gcaaaatcta atccaaaatt ttctagaaaa ggttgtacaa
    17521 atcccggtcc acgaccagtt gctaaaccga ccataatgcc ttgttttttg agttgttgga
    17581 tggctttttg cgttgttttt tggatatttt tacgatcatt gagaagggtc ccatcaatat
    17641 caaaaaagac tgcttttact gtcaaaacct tcttttgcct cctgtgttta tgatagaata
    17701 gattatatca taaataaaag gaagtttgac aatcaaatga aaaaaatcct agtcttacac
    17761 actggtggaa ccatttctat gcaagctgat aactctggta gggttgttcc aaatcaagat
    17821 aatcctatga cgaaaataca tgctgcagcc caagatattc agcttaccgt tagtgatttt
    17881 ctaaatcttc cgagtcctca catcacgcct caccacatgt tatctattta tcatcatatt
    17941 caagaaagaa ctgatgtctt tgatggtata gtcatcacac atggaacaga taccttagaa
    18001 gaaacagctt attttttaga taccatggca ttgcctacta atatacctgt tgtcctaaca
    18061 ggtgctatga ggtcttctaa tgaagttggt agtgatggca tatataatta ccttaccgca
    18121 cttagagttg caagtagtga taaagctaaa gaaaaagggg tacttgttgt tatgaacgat
    18181 gaaatccatg ctgctaaata tgttactaaa acacatacaa ccaatatttc aactttccaa
    18241 acacccacac acggaccgct tggtatcatc atgaaaaatg acctactttt tttcaaaact
    18301 gctgaacctc gtattcgttt tgacttgaga tgcatttctg gaaccatccc cattatcaaa
    18361 gcatacgcag gtatgggcga tggtagtatc ttgagtctat taactccagg tagcattcaa
    18421 ggtctagtta tcgaagctct aggggcagga aatgtcccac cattagcagt tggggagatc
    18481 gagcacttaa ttactttagg tattcctgtc gttcttgttt cccgttgttt caatggtatg
    18541 gcagaacctg tctatgctta tgaaggtggt ggtgcgatgc tacaagaagc aggtgttatg
    18601 tttgtaaaag aattgaatgc tccaaaagcc cgtctaaagt tattaattgc tctcaacgcc
    18661 ggacttactg gtcaagagct aaaagattat attgaaggat aatctagctt cctttagaaa
    18721 tgtcccacta aaacatatta gtgggacatt tctagtactt taagctttaa attaggacat
    18781 ctcctaaatg tctagaataa acaactatgt ttcaaactat gagattgtgc actcataatc
    18841 atttctataa cagtttgaga ccagtattcc aataaatcca actcttagca atcagatacc
    18901 gggtaaacaa gtctttattt tgtctcatta agtatgagct tacttgaata ataacaaaac
    18961 tacttgctta tcctttttta gtaatgatga agacgacctt tttctaagaa cttctttgtc
    19021 ttttaaaata aacaaagcac atattaccct ttattttagt tctcgtttgg aaaaaagaaa
    19081 gacattgcct aaaagataac aaagagttaa accaaaggcc actaatatgc tagtactaga
    19141 aaggtgttta tcaccaagag acaaggatag gtgtttaaac atcaaaactg ggctaatatc
    19201 taacttaaaa aaatggtttg ctaaagtagc agatacttta tcaaaaagaa ggacataaag
    19261 tatataagct gtgattgact gataagtttt acgaagtata ttaaacaaaa attgacacaa
    19321 agcaataata gcaatataaa aaggcagttg tttaatcatc cgatctatga ctattccata
    19381 gtatgcttga ccagtaaata aatgaaatgc taaagcacta agaagataag ttaaactaat
    19441 aaataaaaga gataagccaa aactaactag cagtttatag attataatta aagtacgatt
    19501 ttgttgtttg accacaacat tattaatcgt acggtagtta tagtcatcac taaaaaagat
    19561 acgggctggt gttaaaaaga aaagcgtcac aaaatcagta ataatattaa tgatttgtat
    19621 catgatgact tggttaggtg tcttgcgaaa actataggct acaccaacag caatgacaac
    19681 aagtagcata caagaaaata gagctaaacg ctcttggcgt atccgaaata aatctgcttt
    19741 aagataggaa atcataaaaa cctctttcta aattaatggt gatgctgcat ctttacctaa
    19801 caaatcgagg taataatgtt caaagctcac ttgatgatga taaatgtcaa aaatctcaac
    19861 aggcagatct agaacaattt tgataagctc cattactgat aaagttggtt ttattagtag
    19921 catctgacca tcagtctcaa ctctaagccc caattctaaa agtctatttt ttaccagctg
    19981 atcatcgctt gtatgaaggg caatttgtac ttttacttga gctttaagct ctgctttgtc
    20041 catactctta ataactttgc ctttatgcat aatcacgtaa cgatcaacaa ctaagtctaa
    20101 ttctgataaa atatgactgg aaatcaaaat cgtaatacca tagcaatctc ttaggttcaa
    20161 aataatctga cgcatttctt tgattcctgc tggatcaaga ccattaatgg gttcatccaa
    20221 gattaaaaat tctggaaaat ccagtatcga aagaccaata gccaaacgtt ggcgcatccc
    20281 taaagaataa tctttcacct ttttcttttt gctcactttt tctaacccaa taagttccaa
    20341 aacctcatgt atgcgctctt ttgcatcagc taatctcaat tgcaacgctg catagtaaag
    20401 attatcatga gctgtcatat tgggataaag tgtcggtgac tcaataattg atcccattcg
    20461 atagggttgt aactgtttga tttgccctga atcttttcca attaggccag ataaaatacg
    20521 cattaacgtt gtctttccag caccattttg acccacaagg ccgcaaattt ctcctttgta
    20581 aatatcaaaa gagatatcac ttaaaacctg atttttacca taggatttat ttacttgctc
    20641 aatacttagt aacattgatt gctgtgtcat tttccgctcc ttttttgtac ttatcgatta
    20701 atacaatatc ttacacataa taacatctgt aaa
//
LOCUS       DATWVB010000029        20381 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.029, whole genome shotgun sequence.
ACCESSION   DATWVB010000029 DATWVB010000000
VERSION     DATWVB010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20381
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.029"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            542..931
                     /locus_tag="VCX65_001229"
     CDS             542..931
                     /locus_tag="VCX65_001229"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEP5053691.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFAPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            1025..2077
                     /locus_tag="VCX65_001230"
     CDS             1025..2077
                     /locus_tag="VCX65_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEP5053692.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            2216..3748
                     /locus_tag="VCX65_001231"
     CDS             2216..3748
                     /locus_tag="VCX65_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053693.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVAERVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNKEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVVHDGKIQGIVLPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            3741..4805
                     /locus_tag="VCX65_001232"
     CDS             3741..4805
                     /locus_tag="VCX65_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053694.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            4807..5763
                     /locus_tag="VCX65_001233"
     CDS             4807..5763
                     /locus_tag="VCX65_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053695.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(5981..7699)
                     /locus_tag="VCX65_001234"
     CDS             complement(5981..7699)
                     /locus_tag="VCX65_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEP5053696.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKHGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDESKSSGLIQVIGEDVDMEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVDADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
     gene            complement(7875..8444)
                     /locus_tag="VCX65_001235"
     CDS             complement(7875..8444)
                     /locus_tag="VCX65_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP5053697.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(8502..9047)
                     /gene="coaC"
                     /locus_tag="VCX65_001236"
     CDS             complement(8502..9047)
                     /gene="coaC"
                     /locus_tag="VCX65_001236"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEP5053698.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     IVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(9040..9732)
                     /gene="coaB"
                     /locus_tag="VCX65_001237"
     CDS             complement(9040..9732)
                     /gene="coaB"
                     /locus_tag="VCX65_001237"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEP5053699.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKPLPNKLLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            9913..10764
                     /locus_tag="VCX65_001238"
     CDS             9913..10764
                     /locus_tag="VCX65_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEP5053700.1"
                     /translation="MKGRIVITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKTEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKDFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            10761..11960
                     /locus_tag="VCX65_001239"
     CDS             10761..11960
                     /locus_tag="VCX65_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEP5053701.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     VSYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVINQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNIAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            11957..12955
                     /locus_tag="VCX65_001240"
     CDS             11957..12955
                     /locus_tag="VCX65_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEP5053702.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEEAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            12997..13329
                     /locus_tag="VCX65_001241"
     CDS             12997..13329
                     /locus_tag="VCX65_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEP5053703.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            13322..14134
                     /locus_tag="VCX65_001242"
     CDS             13322..14134
                     /locus_tag="VCX65_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HEP5053704.1"
                     /translation="MPSSFDLLGEMIDLLQTEQLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAQIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKALYDTYLQKENNCE"
     gene            14127..15008
                     /locus_tag="VCX65_001243"
     CDS             14127..15008
                     /locus_tag="VCX65_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HEP5053705.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGPRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILETKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            15055..16074
                     /locus_tag="VCX65_001244"
     CDS             15055..16074
                     /locus_tag="VCX65_001244"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEP5053706.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KRTYQPAIEALHHLGATEVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     DLIFS"
     gene            16202..17872
                     /locus_tag="VCX65_001245"
     CDS             16202..17872
                     /locus_tag="VCX65_001245"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEP5053707.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLLLVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFTEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            17957..19534
                     /gene="cls"
                     /locus_tag="VCX65_001246"
     CDS             17957..19534
                     /gene="cls"
                     /locus_tag="VCX65_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEP5053708.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGHWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMTSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLTQRP
                     WYQKLIGLLVRTIAPLL"
     gene            19874..20212
                     /locus_tag="VCX65_001247"
     CDS             19874..20212
                     /locus_tag="VCX65_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053709.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
BASE COUNT         6245 a         3457 c         4230 g         6449 t
ORIGIN      
        1 taaccttttt taatgtattt taactgaaaa aggctttcat aattttaaaa aaatgttaaa
       61 ataggtgtat aacaactgat taccaagaga ttattatcat tatcttctaa ggtgtcattg
      121 ttatggtgac aatcaaccat acgctactaa agataggtag cgttcgatca caggttgatc
      181 aagtgattga tacagatatt tataatttta caaatatctg tatcaatcca tgttgaatag
      241 tctatgcttc taaggtgtcg acgttaatgt actgacggga ccgttatagt ctttcttttt
      301 ggagaaacgt cggatgccag tgaactagtt gaagttaaag atgttaattc aaacagtgct
      361 gaagagattg atatcgtttt gaacggtcgt ttacttcaaa gcaaagaaat taccagtcta
      421 tcggagatga tataagtgct aaagttagat cacgttaatt atctatcaag tcgggtgcat
      481 atttcgttaa agtatctaca ggggtttcaa tagatgtagc tattatgaaa ggtgatgtta
      541 aatggggact actgatttag taagttgtgc tgtacaagct agtgagtatg cttatgtccc
      601 ttactctcat tttccagtag gagcagcttt aaaaacaaaa gatggaacga tctatactgg
      661 ctgtaatatt gaaaatgtta gttttggtct gacaaattgt ggagagcgaa cagctatatt
      721 taaagccata tctgatggtc ataaagaatt ggttgaaatt gctatttatg gagaaactat
      781 gcaacctgta tctccttgtg gggcttgtcg tcaggtaatg gcagaatttt ttgctccttc
      841 ttctttagtc actttaattg ctaaaaatgg tcaaactgtt gaaatgactg ttggagattt
      901 actcccctat tcttttacag atttaatata atctgcttta atttctgtta tctagccgtc
      961 ttggctttat atttactttc agcaacttat ttgctagaaa tcttttttag gagggttcat
     1021 attcatgaac aagaaattta ttggtcttgg tttagcgtca gtggctgtgc tgagtttagc
     1081 tgcttgtggt aatcgtggtg cttctaaagg tggggcatca ggaaaaactg atttaaaagt
     1141 tgcaatggtt accgatactg gtggtgtaga tgacaaatca ttcaatcaat cagcatggga
     1201 aggcctgcaa tcttggggta aagaaatggg ccttcaaaaa ggaacaggtt tcgattattt
     1261 tcaatctaca agtgaatctg agtatgcaac taatctcgat acagcagttt caggagggta
     1321 tcaactgatt tatggtatcg gctttgcatt gaaagatgct attgctaaag cagctggaga
     1381 taatgaagga gttaagtttg ttattatcga tgatattatc gaaggaaaag ataatgtagc
     1441 cagtgttacc tttgctgacc atgaagctgc ttatcttgca ggaattgcag ctgcaaaaac
     1501 aacaaaaaca aaaacagttg gtttcgtggg cggtatggaa ggaactgtca taactcgatt
     1561 tgaaaaaggt tttgaagcag gagttaagtc tgttgacgat acaatccaag ttaaagttga
     1621 ttatgctgga tcatttggtg acgctgcaaa aggaaaaaca atcgcagcag ctcagtatgc
     1681 agcaggtgct gatgttattt accaggcagc aggaggcact ggagcaggtg tatttaatga
     1741 agcaaaagct attaatgaaa aacgtagtga agctgataaa gtttgggtta ttggtgttga
     1801 ccgtgatcaa aaagacgaag gaaaatacac ttctaaagat ggcaaagaag caaactttgt
     1861 acttgcatca tcaatcaaag aagttggtaa agctgttcag ttaatcaaca agcaagtagc
     1921 agataaaaaa ttccctggag gaaaaacaac tgtctatggt ctaaaagatg gcggtgttga
     1981 aatcgcaact acaaatgttt caaaagaagc tgttaaagct attaaagaag cgaaagcaaa
     2041 aattaaatct ggtgacatta aagttcctga aaaatagtgt ttaagaacaa gaagcgcgac
     2101 ctttgtcggt cgctcttttt aaactgagat aatttttatc tcagtaaagt ttgtgatagg
     2161 tgatagatca taggctttac tgaaataaaa gattgcattg aaaggaaatg atcctatgac
     2221 acagcatgtc attgaaatga gagaaatcac gaaaaaattt ggtgattttg ttgcaaatga
     2281 ccacattaac ttaaatgtca gaaaaggtga gattcatgcc ttattgggtg aaaatggggc
     2341 aggtaaatca actttgatga atatgctagc tggtctctta gagcctacta gtggagaaat
     2401 tgtcattaat gacaagccag ttcaaattga ttcgccatct aaatcagcta agcttggtat
     2461 cggaatggta catcaacatt tcatgttagt agaagccttc acggttgctg agaatattat
     2521 tttaggaaat gaagtagtaa aaaatgggtg cttagatctt aaccaagcat cgaaagatat
     2581 taaggtacta tccgaaaaat atggccttgc aatcaatcca tcagctaaag tttctgatat
     2641 ttcagtagga gcacaacaac gtgttgagat tttgaaaacc ttgtatcgtg gtgcagatat
     2701 tcttatcttt gatgagccaa ctgccgtttt aacacctgca gaaattaaag aattgatgac
     2761 tatcatgaag aatctcgtga aagaaggaaa atcaattatt ttaattaccc ataaactgga
     2821 cgagattcgt gctgtcgccg agcgtgtcac agttattcgt cgtggtaaga gtatcgaaac
     2881 agttgatgtg gcaggagcaa cttcacaaga tttagctgag atgatggtgg gacgctcggt
     2941 ttcctttaca actagcaaaa aagctgctga accaaaagat gtggtcttat ccatcaaaaa
     3001 tcttgaagta gatgaaaata gagggattcc agcagttaag gggctatctc tagatgtccg
     3061 agctggtgaa attgtaggga ttgctggaat tgacggaaat ggtcaatctg agttaattca
     3121 agctattaca ggtttacgta aagtcaaatc tggaagtatt atgattaaaa acaaagaagt
     3181 cactcatttg tcttcacgca aaattactga gttatcagtg ggtcacgtgc cagaagatcg
     3241 tcatcgagat ggtttgatac tagatctttc tttagctgaa aatacagcct tacaaaccta
     3301 ttacaaacaa cctctaagtc aaaatggaat cttaaattat actaaaatta atgactatgc
     3361 tcgtcaatta atgaaagaat ttgatgttcg cggagccaat gagctagtac cagctagagg
     3421 attttctggt ggtaaccaac aaaaggccat tattgctcgt gaagtggacc gtgatccaga
     3481 tttacttatt gttagccaac caacacgtgg tcttgacgta ggagctattg aatatatcca
     3541 taagcgtttg attaaagaac gtgataaagg taaagctgtc ctcgttgtta gttttgaact
     3601 tgatgaaata ttgaatttat ctgatcgaat tgctgttgtt catgatggta aaattcaagg
     3661 tatcgtattg ccagaaaata ccaataaaca agaattgggt attttaatgg caggtggttc
     3721 aattcataag gaggaaggtc atgtctaaaa atgcgcaaaa aattgctgta ccattgattt
     3781 ctgtcttgct aggattttta cttggcgcta ttattatggt tatctttggt tatgatccta
     3841 tctgggggta tgaaggttta ttccaaattg cctttggtag tgttaaaaat attggagaaa
     3901 tattccgttc aatggggcca ttgattttaa tagcgcttgg ctttactgtt gctagccgtg
     3961 caggcttctt taacgttggt ttgtctggac aggctttagc tggatggatt tcagcaggtt
     4021 ggtttgcact cttaaatcca gatatgcctc gtccattatt gattcttatg acagctctta
     4081 tcggaatgat tgctggtggt attgctggag ctattccagg gatacttcgt gcttatcttg
     4141 gtacaagtga agttatcgtt acgattatga tgaactacat cattttatat gtcggaaatg
     4201 ctattgttca acgtggttat cctgagagtg tcaaacaaag tattgattca actattcaag
     4261 ttagtgataa tgctagttat caaacgcatt ggttatcagc cctaactaat aactctcgta
     4321 ttaatattgg tattttcttt gccattattg ccattgccct aatctggttc ttgcttaaca
     4381 aaactacttt aggttttgag attcgttcag ttggtctcaa cccacatgct tcagaatacg
     4441 cagggatgtc atcaaaacgt actatcattt tatcaatgat tatctctgga gctcttgcag
     4501 gtcttggagg agtagttgaa ggtctaggaa cctttgaaaa tgtttttgta caaggatctt
     4561 ctttagcagt tggttttgac ggtatggcag ttagcttatt agcagcaaat tcaccgcttg
     4621 gaatattttt ctcatcattc ctatttggtg tcttaaatat tggtgctcca ggaatgaata
     4681 ttgcaggcat tccaccagaa cttgttaaag tagtaactgc atcaatcatt ttctttgttg
     4741 gttcacatta cctcattgaa cgttacatta ttcgccctaa aaaattagtg aaaggtggta
     4801 aataagatga gtttagtaac aattttcgcc ttattggtgt catctatgct tatttatgca
     4861 acaccactca ttttcacaag tattggagga actttctcag agcgctcagg cgttgttaat
     4921 gttggtttag aaggtatcat ggtcatggga gcgttctctg ggattgtttt caacttagag
     4981 tttgctgaaa catttggaaa agcaacgcct tggatagccg ttttagtcgg tggtattgtt
     5041 ggtttgattt tttctttgat tcacgctgta gcaaccatca actttcgagc tgaccacatt
     5101 gtcagtggta cagtgttgaa cttgttagca ccttcttttg ctgtcttctt ggttaaagct
     5161 atgtacggta agggacaaac agacaacatt caacaatctt ttgggaagtt tgatttccca
     5221 ggtttatcac aaattcctgt gattggtgat attttcttta aaaatactag ccttattggt
     5281 tacttcgcca ttgctttttc gttctttgct tggtttttgc tttataaaac caggtttggt
     5341 ctgcgtttac gatcagttgg ggaacaccct caggcagctg acacacttgg tattaacgtc
     5401 tatttgatga aatactatgg tgtgatgatc tcaggttttc ttggtggaat aggtggagct
     5461 gtttatgctc agtcaatctc cgttaacttt gctgtaacaa ctatcttagg tcctggattt
     5521 attgctttgg cagctatgat ctttggtaaa tggaatccag ttggcgccat gctatctagt
     5581 cttttctttg gcttatcgca aagtttagcc gttattggtg ctcaattacc attactagaa
     5641 aagattccaa cggtttactt acagattgca ccttatatgg taacgattat tattttagct
     5701 gctttctttg gtcaagcagt tgcaccaaaa gctgatggaa tcaactatat taaatctaaa
     5761 taacgttata ttagtagtaa gcctcttagt gaggtttaac agcactccta aagcaagata
     5821 gttaggtcta gctttaaggg tgcttttttg ggacttaccg caagcgtttg gattgccagt
     5881 caccatcaca atagaagcaa gaatagacta aaaagaacta agtcagcggc ttagttcttt
     5941 ttgcttgtct ttcgttttta ctgatagctc ttaagttgtt ttagccaaca aaggtattga
     6001 tttctgtttc aatgttagca attttttctt gagcgatgtc aagagtatca cctattgtgg
     6061 caatatagaa cttgattttt ggttcagttc ctgaagggcg aactgcaatc catgaatcat
     6121 cagctaacgt gtacttcaaa acattacttg gaggagttgt taagttagat attgttccat
     6181 catttttagt agcggtttgt ttttggaaat cttctaataa tacaatatca gtattgttaa
     6241 attgttttgg accattttca cggaatttgt ccataatctt cttaatttca gcagctccat
     6301 ccacacctga aagtgttact gaaatcgttt tttcagcaaa atagccatat tctttgtaaa
     6361 tttcatcaat accatctgca agtgttaaac cacgcgaacg gtaataagct gcgatctcag
     6421 caaccaaaag aactgcttga atagcatctt tatcacggac aaatggttta ataagatatc
     6481 cgaagctttc ttcaaaacca aacatatagg tgtggttatg tttttcttca aactcttgaa
     6541 ttttctcagc gatgaatttg aatccagtta aaacgttaaa cattgtagcg ccataacttt
     6601 cggcaatttt tgttactaat tctgttgata cgattgattt agcgagagca gcattttctg
     6661 gaagtgttcc tgctgtttta tgagcttcca ggatgtattt cgcaataatc gctccaattt
     6721 gatttccaga aaggttttta taagaaccat ctggttggcg aatttcaacg cctaggcggt
     6781 ctgcatcagg atcagtagct actaagacat ctgcatcaac ttctcgtccg agttcttcag
     6841 caagagcaaa ggcagcttgg ctttcagggt taggcgattt aacagtagaa aagtctggat
     6901 ctgccttagc ttgtgattcg actacaacaa cagattcaaa accggcttga gcaagggcac
     6961 ggcgtgtcaa catctcacca gttccgtgga gaggagtata gacaattttc atgtcttttc
     7021 caaagttatt gattaaatct tgattgatat taacatcttt aacctctcta agatattcca
     7081 tatcaacatc ttcaccgata acttgaataa gacctgatga tttgctttca tctaaatcag
     7141 caagttcaac tgcaaatgga ttttcaatag cacggataaa gtctgttagt gcatcagcat
     7201 cagctggtgg tagttgacct ccgtcttgtc catagacttt ataaccattg aaaggtgctg
     7261 gattgtggct tgcagtaacc ataataccag cataggcatt taaatggcga acagcaaaag
     7321 agagttctgg tgttggacga agagcttcaa atacgtaaga tttaatccca tgctgtgcca
     7381 agacctgtgc agactcaaaa gcaaattctg gagagaagtg gcgcgaatca taagcgatgg
     7441 ctacaccatg ttttttagct tcctctccct tagtttcgat taattttgct aatccttcgg
     7501 ttgcttgacg gacaacataa atattaatac gatttgtacc agcaccaata taaccacgca
     7561 taccagcagt accaaattct aagtttgtgt aaaaagcatc ttcttttgtt ttttcatcca
     7621 ttgatagtaa ttcttgacga agatagtcag gaagctgctc aaaatctaac catttttgaa
     7681 aattttctgt gtaagtcatt gaaatactcc ttcaatattt ataaacgctt tcattatatc
     7741 attttgaagg aaaaaaaaca ctaattattt gcagctgttt acaaaacttt ttccatattt
     7801 tcaagtagct aatgtaagaa agttaaaata accaagtttt taaaagagaa aaactcggtt
     7861 attgtgaaag ctaattacct ttttagtctt gatagtgttg gaataagtac aaaggtaata
     7921 atagctgaga tgatcatctc aacaatagcg tttgatgaga tgatggctgt tagtagtgct
     7981 ttaatatttc catcaaaaac tgtcgcgaaa aaaataaata tcccagataa tacaaatata
     8041 gtatttgtta gagaaccaat gataccggat actattaaac caaactgatt aggaatcaat
     8101 ttatagcaat aataaggggt aataccaatc aaaatacgtg ggataatagc aattattaaa
     8161 gaagcgaaag ttccatgatc gacaaaaggt gaaaagagat aatttgtagg cagtagaatg
     8221 atggtatttg taatgacact tataatcccc attaatcctc ctaaaatagc acctatcctt
     8281 gggccatata agacagaagc aataataact gggatatgga caagcgttgg tttgattgga
     8341 ataggccaaa tattaaagac aagactgctc acaaaatgaa tgactaacat gatggcaaaa
     8401 aagatagcaa tacgagaaat atctgctgat ttacggtgat tcattttact ctccaaaaaa
     8461 tataatactt aattctaaaa aggtgatcag aaaaacgact gttaaagttt ccaaatcgta
     8521 tcaatagtag ctaagataac atcaatatca gccaaagcac caggtccttt atctccacag
     8581 gctaataagc tagattttgg aggaatttct gtaaacccta ttgtcgataa gcgtttaata
     8641 ttttcttggg taatagggtt ttgatacatt ttggtattca tggctggggc tattaatttt
     8701 ggtgtggtag ctggtagggc aagagcaaca cttgttacaa tattatcagc gaatccatat
     8761 gctagatgag caatagtatt agcagaggca ggtgcaacaa taaataaatc tgtgcgtttt
     8821 gctaattcga tatggttgat aacttttggg tcatgctcat ccataacatc taaatgaata
     8881 gcattttttg ataacacttg cagggttaat ggtgtaataa attgtgtagc agcctgagtc
     8941 attatgatgt gaacatcata gccaatttta gttaattgac tcgtaagatc tgctgcttta
     9001 taggcagata tactaccaga aacagctaag gtaatatgtt tagtcatgtt tggtcatcct
     9061 ttcatataat aagtcagcaa ttgcctcttt ggtatctgca gatgcaactt cgttattgga
     9121 tatcaaaaga gccttgtgca tacctgtttg gatatcaact aaatcattgg cgagaatata
     9181 atcagcatgg tttttagcta gacttgctct ggctacttta attaactctt cttgaggcac
     9241 attaactaga agtttaaagc cgactagttt aatattagga ttccactgtt taacataaga
     9301 gataactttg ggtgtttttt tcaaaaaaag aacctgataa tcagatgcag atgagatttt
     9361 cggctcactg ttatgttcac atagaaaaca attaaggtta tcagcttgag agacttgttc
     9421 caaatcagtc atgtagactg gagtatagtc agaaacagcc atactatgaa ttagaatgtc
     9481 atggtgagga acctgatctt tgagggcagc cattaagtcg ttaactgttt ccacttcaat
     9541 aatccttagg agcttatttg gcaggggttt agtggctgtt ttagtagtga ctagggtaac
     9601 gtcatgatga tattgtaaaa atcgctctgt gattaatttt ccaagttgcc cagttgagtg
     9661 attagtgata cctcgtactg catctatagg ttcagttgtt ccacctgatg ttattattaa
     9721 tttcatagtc atattttatc aaaaaaggag ctgatagtaa acggaagata atgacgccag
     9781 acattgtctt gcgtttgtat taatatggaa tagtaataga tttctagtaa ttaaaacgaa
     9841 gttctggaaa gcaagacact atagtagcta aaatctaaat tttaaggtaa aatagagcaa
     9901 gcggtttcaa gtgtgaaagg aagaattgtg ataactatta gagatttagc gtcactgccg
     9961 atttttgttt acggtgatgg aaataaaaaa gttccaggag ctttgagtcc ttttgtgtgg
    10021 acagaggtgt ttttaaaaac tatcaatcaa gaacctaatc aactgatctt acatatttgg
    10081 ccgatgacaa gaacagttat attagggatg ttagatagac agcttcccta ctttgagctg
    10141 gctaaaacag agattggcaa taatggttat gttcctgtta ctcgtaatat tggcggtttg
    10201 gctgttgtcg ctgatgatgg gattttgaat ttttcgcttg ttattccaga ccatttttcg
    10261 gaatctatca gtattagtaa tgcttattta ataatggttg atgtcattag agagagtttt
    10321 tcggattatt atcagcgtat tgaatatcac gaaattaaaa attcttattg ccctggtaat
    10381 tttgatctta gtattgcagg ccgcaagttt gcaggtatcg cccagcgtcg tatcaaaaag
    10441 ggaattgttg tgtctattta cttgagcgtt tgtggggatc aagcagcgcg tggtcaactc
    10501 atcaaggatt tttatgaggc cggaacacaa ggagaagtta ccaaggttaa ttaccctcaa
    10561 attgatccag aatgcatggc aactctttca gaactccttg agacgccttt tacagtggca
    10621 gaagtccttg aacgtcttcg attgaccttg cgacagcttg gcttttccct cacggaaaaa
    10681 agtccagatc aagccttact gactaatttt gatgctgtct atgaacggat gcagctagaa
    10741 gtcgtcagaa aggaaggcaa atgaaagaaa gatttagtcc tttatttgag cctttgactt
    10801 tgccaaatgg gagtcaattg gataatcgct ttgttttgtc tcctatggtg accaactcat
    10861 ccacaaaaga cggttatgtc acccaagatg atgtatccta tgctttgaga cgagcagctt
    10921 ctgcccctct acaaattaca ggagcggcct atgtggatcc ttatggtcaa ttgtttgaat
    10981 atggttttag tgttacaaaa gatgccgata tttctggctt gaaagagcta gctcaagcga
    11041 tgaaggcaaa gggagctaaa gctgtcttac aactgaccca cgctggccgg tttgctagcc
    11101 atgccttgac taaatatggc tttgtctatg ggcctagtta catgcagttg agatctcccc
    11161 aacctcatga agtcaaacct ttaacaggtc agcaaataga ggaattgatt gcagcttacg
    11221 ctcaggccac tcggcgggca attcaagcag gctttgatgg cgtggaagta tcttcggcgc
    11281 agcgcttatt gattcaaacg ttcttttcga ctttttcgaa caagaggaca gatagttatg
    11341 gttgtcaaac actttttaat cgctctaagt taactttagc tgttttgcaa gctgttcaac
    11401 aggtgattaa tcaagaagct cctgatgggt ttatttttgg atttcgtgct acaccagaag
    11461 aaactagggg aaatgatatt ggttatagta ttgacgagtt tttgcagttg atggattggg
    11521 tacttaatat tgcaaaactt gattatttag cgatagcaag ttggggccgt catgtatttc
    11581 gaaatactgt tcgttctcct ggcccttatt atggaaggcg agttaatcag gtagttagag
    11641 attatttaag aaataagcta cctgttatgg ctacaggggg aatgaacaca cctgacaaag
    11701 ctattgaagc actagctcat gctgatttta ttggagtatc tacacctttt gtcgtggatc
    11761 cagaatttgc tcataaaatc aaagaagggt gtgaagagag tattcattta aggattcgac
    11821 ctgctgattt gaaaagttta gcgattcctc aggcttcttt caaagatatt gtacctttga
    11881 tggactacgg ggaatcattg cctaaagaat caagaacttt atttcgtagt cttactcaca
    11941 attataagga gattaaatga aagtcagtat tcttgattat ggggtgattg ataaagaaaa
    12001 aacaccccaa gaagctttat tagaaacgcg ctgcttagca caagtagccg acaaacttgg
    12061 ttttcatcgt ttttgggtag cagagcatca taatatttat gcctttgcaa taagcagtcc
    12121 agagctgttg atgatgcatt tagcagatca taccaaacag attcggatag gttcaggagg
    12181 tattatgcct ctacattata gtagctttaa gattgcagaa tggataatga ctttagaggc
    12241 cttgcaccct aatcggattg atttaggtat tggcaactct ttaggaacta cgttagttca
    12301 aagagctcta tcaagtatcc attgcaaaga cagctatagt caggttgtca cagaattata
    12361 ccagtatctt aatcctgatc atttgtcacc actaccgatt tttgttaacc ctaggggtaa
    12421 tacttaccct cagatttgga cgctaagcaa tagtttggag acagcagaac tggctggtca
    12481 attaggttta ggctatacct ttggtatttt cccctatata ccaaaagatc ctataacaga
    12541 agctaaaaga gtatcggcac attatagaaa ggcttttagg ccttcaaagc tattaaaaat
    12601 ccccaagtta atattagcag tttttattgt cctttctgat accgacgagg aagcagaagc
    12661 tttggctaaa ccgttggaca tttggatgct tggtcagcaa gattttaatg aatttaagac
    12721 ctaccctgat gttgaggagg ctagaaacta tcacttaaca gagaaacaaa gagaagccat
    12781 tgcagcaaat cgtagtcgca tggttattgg atcacctcac acagtcaaga aacaattgga
    12841 taggctgata gaagcttgtc aagctgacga attattagcc atccccttag ttcctgaatt
    12901 tgccaataga caacgaacct tagagctgct agcagactta tacgtgacca tttaacctta
    12961 ccaaaaacaa ttccctaaac tgaaaggaaa gaaacaatga aaaaaattgc aaattactta
    13021 ttaattgaga aaacagatga ccgctatacc attagcatga caccagaatt acaagacgat
    13081 attggtacta ttggttacgc tgaatttacg gataacgacc accttgccgt tgatgacatt
    13141 atcttaaatc tagaggcttc taagaccgtc atgtctgtct tgtcaccatt ggctggggca
    13201 gttgttgagc gcaatgaggc agccacacta acaccaaccc ttttgaattc agaaaaagct
    13261 gaggaaaatt ggattgttgt gctaacagat gttgatcaag cagcttttga tgccttagaa
    13321 gatgcctagt tcatttgatt tattagggga aatgattgat ctgttgcaaa cagagcagct
    13381 tactagttct tgggcctgtc ccttgcctaa tgctttaaca aagcgacaag acttgtggcg
    13441 ggcgctcatt aaccagcgcc ctgctttgcc tttatcaaaa gattacttga atctggaaga
    13501 tgcttatcta gatgattggc gtgcttcttt tgttcctgta tcagtcaagg actgccaaaa
    13561 aactaattat accagtcttt ttctttacca tggggatatt aggtaccttg ctgtggatgc
    13621 tattgtcaat gctgctaata gtgagttatt gggatgtttt atccctaacc atggctgtat
    13681 tgataatgcg attcatacgt ttgccggaag tcgtttacgc ttagcttgtc aggcaatcat
    13741 gactgaacaa ggccgtaagg aagccattgg ccaagcaaag cttaccagtg cttatcatct
    13801 accagcctct tatattattc ataccgtagg gccaagaatt accaaaggac gacacgtttc
    13861 tccgattcga gctgatttgt tagcacgttg ttatcgttct agtcttgatt tggcggttaa
    13921 agcaggattg actagcctag ctttttgctc tatttcaaca ggagaatttg gctttcctaa
    13981 aaaagaagcc gctcagattg ccattaagac agttttaaaa tggcaagcag aacatccaga
    14041 atctaagact ttaactatca tttttaatac ctttacatca gaagacaagg ccttatacga
    14101 cacttatttg caaaaggaga ataactgtga gtaattggac aacctatcct cagaaaaatc
    14161 tcacccaggc agaacaactg gcccaattaa tcaaagaagc agatgcactt gtagttggta
    14221 ttggagctgg catgtctgca gctgatggtt ttacttatat cgggccgcgt tttgagacgg
    14281 cattcccaga ttttattgct aagtatcagt ttttggatat gctgcaagct agcctttttg
    14341 attttgaaga ttggcaagaa tattgggctt ttcaaagtcg ctttgtcgct ttgaattatc
    14401 ttgatcagcc cgtaggccag tcttatcttg atttaaaaga gattttggaa accaaagact
    14461 atcatattat tactactaat gctgataatg ctttttgggt ggctggttat gatcctcata
    14521 acatttttca cattcaagga gaatatggtt tgtggcaatg tagccagcac tgccatcagc
    14581 aaacttataa ggacgatacg gtcatccgtc aaatgatcgc agagcaaaaa aacatgaaag
    14641 tcccaggtca actgattcct cattgccctg aatgtgaggc gccttttgaa atcaataagc
    14701 gtaatgaaga aaaaggaatg gttgaagatg ctgactttca tgcccaaaaa gcacgttatg
    14761 aggctttttt atcagaacat aaagagggta aagtgcttta tctagaaatt ggtgtgggac
    14821 atacgacgcc tcagtttatc aaacacccct tttggaaacg tgtctcagaa aaccctaatg
    14881 ccttattcgt taccttgaat cacaaacatt accgcatccc tctgtcaata aggcgacaaa
    14941 gcctagaact gacagaacac attgcacaat tgattagcgc cacaaaaacc atttaccaaa
    15001 aatcgtaacc aaagccaata gacggttaat taagagatat agaaggagac taacatgtac
    15061 cttattgaac cgattcgtaa cggtaaacgt atcaccgatg gagctgttgc tctagccatg
    15121 caagtttatg ttcaagaaaa tctattttta gatgatgata ttttatttcc ctactattgt
    15181 gatcccaaag ttgaaattgg aaaattccag aatgcggttg tagaaactaa tcaagagtat
    15241 ttaaaagagc atcatatccc tgttgttcgc cgagatactg gcggtggtgc cgtttatgta
    15301 gattctggtg ctgttaatat ttgctacttg attaatgata atggtatttt tggtgatttt
    15361 aaaagaacct atcagcccgc tattgaagcc cttcatcatt tgggagcaac agaggttgaa
    15421 atgtctggac ggaatgactt ggttattgat gggaaaaagg tatctggcgc tgcgatgact
    15481 attgctaatg gccgtgttta tggggggtat tcccttttgc tagatgtgga ctttgaagcc
    15541 atggaaaaag cattaaaacc taatcgcaaa aaaattgaat caaaaggcat caggtcagtt
    15601 cgtagtcgcg ttggaaacat cagagaacat ttagcaccac aataccaagg tattacgatt
    15661 gaagagttca aagatttaat ggtttgccaa ttgttacaga ttgagacgat tagccaagct
    15721 aagcgttatg atttaacgga aaaagactgg caacaaattg atgctttaac agagcgtaaa
    15781 tatcacaatt gggaatggaa ttatggcaac gcgcctcaat accgttacca tagagatggc
    15841 cgttttaccg gtggaacagt agatattcat ttagatatta aaaaaggcta tattgcagct
    15901 tgtcgcattt acggagattt ttttggcaag gcagacattg cagaacttga aggtcacttg
    15961 ataggaacac gaatggaaaa agaggatgtc ttagctaccc tcaatgcaat tgatttagcc
    16021 ccttatttag gtgcgattac agcagaagaa ttaggagatt tgatattttc ttgataaaaa
    16081 agatacctca gaccggtaaa gtgcgattaa aaacgaacaa taattgtttt aattcaaata
    16141 aatgtatgta tgatatgaat tgtgatataa tgacgtcatt acgtaaaatt gaggagtcat
    16201 catgaaatca gatatcgaaa ttgcccaaag tgtcgcccta caaccaatca ctgacattgt
    16261 taaaaaggtt ggaatagacg gcgatgacat tgagctttat ggcaaatata aggctaaatt
    16321 gtcttttgag aaaatgaaag ctgtcgaagc taatgagcct ggaaaattac tcttggtaac
    16381 tgctattaac cctactccag cgggagaagg aaaatcaacc atgtctattg gactggcaga
    16441 tgccttaaat caaatgggaa aaaaaaccat gcttgcctta cgtgaaccct cccttggtcc
    16501 tgttatgggg attaaaggcg gggcagcagg tggtggttat gcccaagtat tgcctatgga
    16561 agacattaat cttcacttta ctggtgacat gcatgccatt acaaccgcta ataatgcatt
    16621 atctgctttg attgacaatc atttgcagca aggaaacgat ttaggaattg atcctcgccg
    16681 cattatttgg aagcgcgtgt tggaccttaa tgatcgtgct cttcgtcagg taattgttgg
    16741 cttaggcagt ccagtgaatg gtgtgccacg cgaagatggg tttgatatca cagtagcttc
    16801 tgaaatcatg gcaattttat gtttggcaac tgacttgaaa gatctaaaga aacgtcttgc
    16861 tgatatcgtc gtggcttata cctatgatcg taagcctgtc tatgtgcgtg acttgaaggt
    16921 tgaaggagca ttgacattaa ttctaaaaga tgctatcaag ccaaacttgg tgcagactat
    16981 ttatggaaca ccagctctta ttcatggggg gccatttgct aatattgctc atggttgtaa
    17041 ttctgtcctt gctacctcaa cagctttgcg attagcagat tacactgtta ccgaagcagg
    17101 attcggggcc gacctaggag ctgaaaaatt cctaaatatc aaagtaccta atcttcctaa
    17161 agcaccagat gctatcgtca ttgttgcaac cttgcgcgcc cttaaaatgc atggaggtgt
    17221 cgccaaatca gatttagccg ctgaaaattg tgaggctgtt cgcttaggat ttgccaactt
    17281 aaaacgtcac gtggaaaaca tgcgccaatt caaagttcca gttgtggtgg ctatcaatga
    17341 atttgtagca gataccgagg ctgaaattgc taccttaaaa gcgctttgtg aagagattaa
    17401 ggttccagta gaattagcca gtgtttgggc aaatggagct gagggaggct tagcattagc
    17461 taaaacagtg gttcgtgtga ttgatcaaga agctgctgac tacaaacgtc tctattcaga
    17521 tgaggatact ttggaagaaa aagtgatcaa tatcgttacc cagatttatg gtggcaaagc
    17581 tgttcaattt ggccccaagg ccaaaacaca attgaagcag ttcacagaat tcggttggga
    17641 taaattgcct gtttgtatgg ctaagaccca atacagtttt tcagataacc catccttgct
    17701 tggagcgcca accgattttg atattaccat tcgtgaattt gttcctaaaa caggggcagg
    17761 ttttattgtt ggtttaacag gtgatgtgat gaccatgcct ggtttgccta aagttccagc
    17821 tgccatggca atggacgtag cagaaaatgg cacagccctc ggtctctttt aggaaaaatt
    17881 gctcgaataa ttcgagcaag cgctcctttc ttcccgcttt actgtgatat aataaggtaa
    17941 ctgagatttt ggagggatga ttatcaaaaa gaaagcaaaa gtaaaatatt tgctccataa
    18001 agggaaacat ggatttttaa gaggaatttt tagtagaaca acaatcattg tattattaat
    18061 tattttgcaa ttagttttct tatttcaatc ttatgcctgg atggagcagt accgtgtttg
    18121 gataacgatt cttgaaagtg tctttgctat tactattgtt ttatatttag ttaatagtga
    18181 tatggatgct atttcaagaa tgacgtggtt aattttgatt atgattgctc cattactagg
    18241 gtcactgttt ttaatttata caaaattgga ttggggttac agagggctaa aacaaagaat
    18301 aaatcatctt gtagatctgt ctgcacctta ccttagcgat gatgacgcta tattagaggt
    18361 attaaaggat agcacatcaa ccacatatca tttagtacag tacttagaaa gaagtcgtgg
    18421 caactttccg atttataata atacaagggt aacttacttc ccaacaggtg aaactttttt
    18481 tgatagttta aaagaacagt tattcttagc taaaaagtac atttttcttg aattttttat
    18541 tattgcagaa ggccaaatgt ggggagaaat ccttagtatt ctagaaaaaa aagtcagtga
    18601 aggtgtagaa gttagggtgt tgtttgatgg catgaacgaa ctatcaacgc tatcatcaga
    18661 ttacgccaag agattagaac aaatagggat taaagctaaa tcatttttac cgatttcacc
    18721 ctttatctct acctattaca attatcgaga tcaccgaaaa attgtcgtta ttgatgggga
    18781 ggtatcattc actggaggta ttaatctagc agatgagtac attaatgaag tagagcgttt
    18841 tggccactgg aaagatgctg gtttaatgct tgagggtgaa gcaacagaca gctttttaat
    18901 tttgttttta caaatgtggt ctatcacaga aaaagaactg attattgatc cttatctttc
    18961 agatcattct ttaaaacttc cttcagatgg ctatgttatt ccctacggtg attccccgct
    19021 tgatactgat aaaataggta aaaatgttta tatagacatt ttaaatcatg ctaaagagta
    19081 cgtttatatc atgacacctt accttatttt agatagcgag atggaacacg ctttacgatt
    19141 tgcatcagaa cgtggagtag atatccgaat tattatgcca ggagtgccag ataagggggt
    19201 accatatgcc ttagctaaaa cctattataa agctttgatg acttctggag taaaaattta
    19261 cgagtatcaa ccagggttcg ttcattcaaa ggtatttatc tctgataata caaaagcagt
    19321 tgtcggaaca attaacttag actatcgtag cctttatcat cattttgaat gcgcgactta
    19381 tttatatcgt gtgtcagtta ttgctgatat tgtgaatgac tttaatgaag ctcaaaagca
    19441 atcactattg atgacatcag atcatttgac gcaacgtcct tggtatcaaa aattgatagg
    19501 attattagta cgaacaattg cccctctctt gtaattttcg taaaatatgt tataatatct
    19561 gtatgcgatg agtcgattgt gactgcaaag tcacttttgc gcaggggagg tcattaaggc
    19621 gggaagccga ctttgataat ctgtgtgaac cattttatca caatcttatt tattaagaat
    19681 gccccttgga ttgagatatt ctcaatcctt tttttaattt tattatctta gttaaaattc
    19741 agaatgtatc agtgattact gtgtttcaaa ataagaaagt agtttttcgg gtatgagtgc
    19801 tatgacttga caaatgctaa taacatttgc ataatgtaag tagagatgaa aacttatgaa
    19861 aagagatgat cttatgcaaa ttattaagcg tgatggccac gttgctgatt ttgatccaga
    19921 taaaatttat caagcaatta ttaaagcagc aaggacggtc tatgttattg atgacacgtg
    19981 gcgacaaaac ttaacacatg tcactaaaaa agtagttatt gatttagaag aagcacatgt
    20041 agaacgtcct actatcaata tggtccaatc ccttgtggag aatcgtttga tggatgctgg
    20101 atatattacc attgcagaac attacatttc ttatcgtctt cagcgagatt tagagcgcaa
    20161 tggctatggt gataagattg tggttcactt gcgttttgaa caaataaaat aaaaacgctt
    20221 ctaatggcat tttagtgtct ttgaggggat aaggtttaaa tacctaacag ataaaaatct
    20281 gttaggtatt tttttgctac tattaggtgt attctatatc acatagaact taagcattca
    20341 agctttaatt taactttctg tttatttttt gctacatttt g
//
LOCUS       DATWVB010000030        19565 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.030, whole genome shotgun sequence.
ACCESSION   DATWVB010000030 DATWVB010000000
VERSION     DATWVB010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19565
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.030"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..407)
                     /gene="speG"
                     /locus_tag="VCX65_001248"
     CDS             complement(<1..407)
                     /gene="speG"
                     /locus_tag="VCX65_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
                     /protein_id="HEP5053710.1"
                     /translation="MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPC
                     DYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSLGITDQFIKGDKVDVFGLPYNFS
                     PPYVDNIYGGIVKHSNQGNKSLQFVGILNQDGK"
     gene            complement(509..606)
                     /gene="ffs"
                     /locus_tag="VCX65_001249"
     ncRNA           complement(509..606)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VCX65_001249"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            806..2038
                     /locus_tag="VCX65_001250"
     CDS             806..2038
                     /locus_tag="VCX65_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEP5053711.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNVYQDLQAIGNDIVANTPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQAQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDYLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILASLENQLLNRQEQLCLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            complement(2652..3167)
                     /locus_tag="VCX65_001251"
     CDS             complement(2652..3167)
                     /locus_tag="VCX65_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEP5053712.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(3167..3946)
                     /locus_tag="VCX65_001252"
     CDS             complement(3167..3946)
                     /locus_tag="VCX65_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEP5053713.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFA
                     KLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PEGIDPDNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            complement(4089..4625)
                     /locus_tag="VCX65_001253"
     CDS             complement(4089..4625)
                     /locus_tag="VCX65_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEP5053714.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLAAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTK"
     gene            complement(4629..4940)
                     /locus_tag="VCX65_001254"
     CDS             complement(4629..4940)
                     /locus_tag="VCX65_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053715.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCAFCQTYYACYHCHDQ
                     LTDHAFVPTGHQETSPVICGHCRKLLSLAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            complement(5157..6299)
                     /gene="tgt"
                     /locus_tag="VCX65_001255"
     CDS             complement(5157..6299)
                     /gene="tgt"
                     /locus_tag="VCX65_001255"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEP5053716.1"
                     /translation="MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            6518..7381
                     /locus_tag="VCX65_001256"
     CDS             6518..7381
                     /locus_tag="VCX65_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEP5053717.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGVILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGGSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDKVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKK
                     PTPMMYDDQKD"
     gene            7467..8809
                     /locus_tag="VCX65_001257"
     CDS             join(7467..7917,7917..8809)
                     /locus_tag="VCX65_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP5053718.1"
                     /translation="MKFNQETKVKIYELRQMGESIKSISKKFDMAESDLKYMIRLIDR
                     YGVTIVQKCKNNYYSPELKQEIINEVLIDGQSQKQTSLDYALPTSSMLSRWIAQYKKN
                     GYTILEKPRGRPSKMGRKRKKNLEEMTEVERLQKELEYLRAENAVLKKPERIPLEGRS
                     KAQRATEIIQALRNQFPLEMLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDE
                     HKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMSLAARIRRKRKYSSYKGEVGKKADN
                     LIKRHFEGSKPYEKCYTDVTELALPEGKLYLLPVLDGYNSEIIDFTLSRSPNLKQVQT
                     MLEKTFPADSYSGTILHSDQGWQYQHQSYHDFLESKGILPSTSRKGNSPDNGMMDSFF
                     GILKSEMFYGLETTYQSLDKLEEAITDYIFCYNNKRIKAKLKGFSPVQYRTKSFQ"
     gene            complement(8858..9589)
                     /locus_tag="VCX65_001258"
     CDS             complement(8858..9589)
                     /locus_tag="VCX65_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEP5053719.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRL
                     DKDTRGLLLLTNNGQLAHDLLSPKKHVTKEYLAKVVGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQRTSLVKITIQEGKFHQVKRMVAACGKGVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYCQSSL"
     gene            9704..10069
                     /locus_tag="VCX65_001259"
     CDS             9704..10069
                     /locus_tag="VCX65_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEP5053720.1"
                     /translation="MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            complement(10189..11409)
                     /locus_tag="VCX65_001260"
     CDS             complement(10189..11409)
                     /locus_tag="VCX65_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP5053721.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLSL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLCFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     SIGQLKAERYQQLR"
     gene            11783..13267
                     /locus_tag="VCX65_001261"
     CDS             11783..13267
                     /locus_tag="VCX65_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEP5053722.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLKKNGIASYLHYPIKSYPTDINHIISSEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCISQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            complement(13372..13773)
                     /locus_tag="VCX65_001262"
     CDS             complement(13372..13773)
                     /locus_tag="VCX65_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEP5053723.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKTSLTMFVTGRRHNG"
     gene            complement(13858..14639)
                     /locus_tag="VCX65_001263"
                     /pseudo
     CDS             complement(13858..14639)
                     /locus_tag="VCX65_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            complement(14791..16470)
                     /locus_tag="VCX65_001264"
     CDS             complement(14791..16470)
                     /locus_tag="VCX65_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEP5053724.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRKQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGLSKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGAGMFGNKCTKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFRKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKIIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLITAL
                     ISEIQVYEEKQPNGQWLKSITFKLPIIDDDLNISLDNNEQVECVSLLEKRS"
     gene            complement(16567..16728)
                     /locus_tag="VCX65_001265"
     CDS             complement(16567..16728)
                     /locus_tag="VCX65_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053725.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     KAKTQIETD"
     gene            complement(17426..18154)
                     /locus_tag="VCX65_001266"
     CDS             complement(17426..18154)
                     /locus_tag="VCX65_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEP5053726.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTEIMINKLSRYMESSGKTYQNHYATILNWY
                     DKDKDKLRQKSLNKKMNYDVGESL"
     gene            complement(18280..18807)
                     /locus_tag="VCX65_001267"
     CDS             complement(18280..18807)
                     /locus_tag="VCX65_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEP5053727.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKAAKESINLEKEIRKKMNDTLE
                     KANGNLKSLMGDEIKIKDLYKKGQLENISIDQSNLKDLKKELNKLGVSFSVMKNKESQ
                     NYEVFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKNKTKEKVKRKV
                     KEKVKPNKKDMTREI"
     gene            complement(18991..19164)
                     /locus_tag="VCX65_001268"
     CDS             complement(18991..19164)
                     /locus_tag="VCX65_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004829396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053728.1"
                     /translation="MNKRQELIDELIKADQDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHTNC"
     gene            complement(19238..19495)
                     /locus_tag="VCX65_001269"
     CDS             complement(19238..19495)
                     /locus_tag="VCX65_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053729.1"
                     /translation="MVNLEEINKEKDKIKDEYQEINHIKYSVDFVNKELGIDLSIEID
                     KLIKQGEKPSVIAQIKKFQDQVNKDNEYRESMKNKKMDQER"
BASE COUNT         5789 a         4000 c         3338 g         6438 t
ORIGIN      
        1 tctttcccat cttgatttaa aattcctaca aactgtaatg atttatttcc ttgattcgaa
       61 tgttttacaa taccaccata aatattatct acataaggtg gggaaaaatt ataagggaga
      121 ccaaaaacat cgaccttatc cccttttata aactgatcag taatgcctaa agatacaata
      181 gaatcaacat aaagaataca ttccgatctt ttttgtttag tattaatatg tatgctattt
      241 gtagtaacaa atgcaatttc tacattttca taatcgcatg gggtaatatt ataggcaaac
      301 cttaaacttc tttttaaatc ttttaaattt tcatctgcat aagctaattg acttccatag
      361 ctaaaaacac atgataatat gataattgtc aaaatgtttg ttttcattta aaacttttta
      421 tgtcctgttt tatacctctt aacctaaata aaaatatcaa tcggtttcaa caactgatga
      481 cactatagaa ggaggagatt actttagtaa agtcaacaaa aaagagcaca cacccgaaaa
      541 tcgcttaggg ctgctggatt cctcccctga cccacttcac gcacaagtgt tgctccgcct
      601 attattatat catattacgg acagtttgca agttttccaa ctaagtaaaa tcactttcaa
      661 gtgagcatag cttcattttg ggacaagatg gactgaatac ctagaaaaat catgaccctt
      721 tccaaacacg attttgcttt ttgaaaatct ttccctctcc ccattccagc tattctctat
      781 gttataataa gattattaga ttagaatggg agttatgatg aaacaaaaga ttaaaatctt
      841 aacagtaatt ggccttatga cagttggtat gtctgcgtgt cacaacacta gcaaaccttc
      901 taataccgat tctgtttttt ctttaaccgg aaaaaagcgc caacaaatcg tcaaacaagt
      961 aagacaacgg tattatttcc aacaattatc caaaaccgaa caagaaaatt acctcacttt
     1021 atacgatagt ctagcacaat ttcgtgaaat catcagtttg acgccggctt ctaaaaaaag
     1081 cttaattaaa acgattgacg cctttgtgat ggataatccc gaattttact ggattacatc
     1141 tgccgattat cgatttgagt tttctgatca aacggtcttt gtcacctttc ctatcccaga
     1201 agatgccaag aacgtttacc aagacttgca agcaatcggt aatgatatcg tcgcaaacac
     1261 gccatcaaag gatcgctatg agcaggtcaa atatttttat gaggtcatca ttcgagacac
     1321 agactacaat aaaaaagcct ttgaagccta tcaatcaggc agtcaagccc aggtcgcttc
     1381 taatcaagac attaaaagtg tttttattga tcatttatct gtttgtaatg gctatgccca
     1441 agcctttcag tttctttgtc aaaaagctgg cattccagtc gcctatatcc gtggaactgg
     1501 tacatctcag caacctcagc aatcttttgc acatgcatgg aatgctgttc aaattaataa
     1561 cacttattat ggcgttgatg tcacttgggg tgaccctgtt tttgataacc atctctcaca
     1621 tcaaaagcaa ggaactatca attacagttt tctatgcctg ccagattatc taatggcctt
     1681 atcacatcag ccaagcaaag acattgcttt taatactaaa gaacgttttg aaaatgtttg
     1741 gactatacct tcttgtacag atgattcttt gctttattct aaacgtcatc aaagctatat
     1801 ctcaacgttt gacagtgacg ccatccttgc aagccttgaa aatcagttgt taaatagaca
     1861 agagcaacta tgtctacaat ttgctcatca agatgattat caacagatgg taactgattt
     1921 aacgacgaat caaacaggtt atcataacct tttcaatcag tattggaata attatacggg
     1981 ctttacctat ggactcttac cagagactct tagtatttca tttgctagta ggaactaggt
     2041 ttagacacat gaaacacaaa gttaagatga ttatctttgt caaacattac aagaaattga
     2101 tatactgaca caattgaagg cgattattat tctaaccgtc ttcaatagat ataacctttt
     2161 cagattgagc acatctaatg cttgtaacat tagcaacagt gatgagctct tttttaatgc
     2221 tttagcaaaa tatatcagct aagacaaaag attaaataac tcaagccatg cctataagtc
     2281 acttgttttt aatccctgtg tcagtgtcaa tctacgccac agataactga cagctctgag
     2341 ccttagaagt ctgagctgga taagtttact aaaaacaaaa ataaggtgag ccattactat
     2401 ctgtttttag atagtaaatc tttttaagaa tgactaactc atctagtcat cacgtgtttt
     2461 atttttcgat tgttttcacc tcgattgggt ctgaaaaaga gcgcttctag tacttggaaa
     2521 cgcccttttg tatattctat cttcgtatgt tgaatctaac aaccattgga aaaatggtct
     2581 aacgtttcac tcattatttt gacaggttac ccttcaccaa aaatgcatgt gataacaagc
     2641 tccttaaaac tctaatcaaa gggatctgac tgttccttga tcaaatgctt agctattttt
     2701 ttgcgctctc gcccttggcg gaaaaaggtt tgcatgatat tagcacagtc tgctgctagc
     2761 aggcctcgtt caacttgtac gcggtggttt aagcgctcat ctgtcaaaat ctggtaaagg
     2821 ctgtctgctc caccaaattt ttgattgctg gctccataaa taacatgcgg aatccttgct
     2881 agcccaatgg caccactaca catcacacaa ggctcgatgg tcacaaagag tgtggtgtct
     2941 aataaacgcc agttgccttc atgagcgtta gcctcgttaa tggccatcat ttcagcgtgc
     3001 ataatggctt ggttactctc ttcacgcgca ttgtgcccac gaccaataat ctcaccatcc
     3061 ttgacaatga cacagccaat ggggatttca gctttctgta aggatttttc ggcttctttt
     3121 aaagcctctt gcatgaaata agtttgctct tctaaactat atggcatcaa gaaagactcc
     3181 ccaagttcca agatttgtgt ggtaaggcaa ggtcaacagg aatattacct gcataggctt
     3241 gtgtttcttg cctcaacact tccaagtgat tgtcaggatc aataccttct ggaggaaccg
     3301 gtggcatgtg ggtcaagaca agcttcttaa cacctgcctg gctagccatt agtcctgctt
     3361 ccttactggt caaatgggcc atatgatttt cattgccttc gtataagtaa acatctgcta
     3421 agaaaaggtc tgcttctttt gcgaagtctg ccaatccttc aaaataacca ctgtctccag
     3481 taaagacaag tacctgacca gtcgctcttt ctacaattcg aaaggcataa cacacaactg
     3541 gatgaactgt tttaagaaag gtaatgtcaa aaggaccaat ctgttcaact ccagtgacat
     3601 cataggctct accttctgaa acatcaggaa tgcttaactt agcaaattcg tgtcggtcct
     3661 catcatgccc ataaatgggc aatactttag gctgccacag gtgtttagga taaagttgaa
     3721 aataatggcg caacacgcct aaatcggcca cgtggtctgg atggtaatgg ctaataatca
     3781 ctgcatccaa atcgagagga ctgatttctt tttccagctc attgagcgct cgactaccag
     3841 catccatcaa taactgaaag ccgtcatgtc ctgtgaccaa ataagaggtt gtgcctgcat
     3901 cttgataggg ataggctccc caagacccta aggtggttaa tttcatctca aacccttctt
     3961 tcttgcttta actcttatta taacaaaaat tagtgtcaaa gaggattgag acccaccaaa
     4021 aacaggtcct agcagataaa tctgccaaga cctgttcaac acaacttaac tatttgatga
     4081 ttagattact attttgtatt caaaaaacta tctttgtatt taacagcgat aatggtcgca
     4141 atgattgctt tgatggtatc tcctggaata aagaccaagt ttgacaaaag cgatgtcaca
     4201 agagacatgc cagtgtaggc tgccaaccag atagcaccca gaacatcaac cagtacaact
     4261 cctgagatta aaagagctag gaatgccaat ggcgtgcttt ttgagaacca gttgcggtaa
     4321 agtaatgaaa agacaatagg cacaagaagg taggcaataa catagccagc agatggcccc
     4381 atcaatactg gaatggttgt tcgtgagcct gagaaaacag gtaagaaaag gccaatcact
     4441 aaaaataaga aaacagataa ggttcccttt ttaccaccca gcatcaatcc agccaacatg
     4501 acacctaagt tttgtaaaac aatagggact gggataaagc ctagcgggat agcaggaata
     4561 aagcctaaaa taataatcaa agtggtcatc atagccacct taacaagttc tttggttgta
     4621 aacatctgtt acgactcctt taaaaaatag atatccttgt gcctatgaca ggctggatta
     4681 aagggacttt gacaataagg acagcatcca caaccatact cagctaggct caagagcttt
     4741 cgacaatgcc cacaaataac aggagatgtt tcttgatgtc ctgttggcac aaaggcatga
     4801 tctgttaact ggtcatggca atggtagcaa gcataataag tctgacaaaa agcacatttg
     4861 agcccaacaa tatcaagcgg ggtatgataa tgtaggcacc gatactcttg gtcaaggtca
     4921 attccaaaac agtccgtcat atctcatcct cttgtaacag tttaatcaaa agcatatgat
     4981 ttgtcaactc tatttttaca aaagggtaac tgttttctga aaaagaacac gtaaaacaag
     5041 aacttccctt taaagaggga cctatcagtt gaaagcaata ggacatccgt ctatacaaaa
     5101 aaactgaaac caaagacgat agatcgccct cagttccagg atcatagcat ttttaattag
     5161 aaattacggt ttgatttatt ataaccatac cgttcaagaa aatcttggcg gaattcaagt
     5221 aagttatcgt ccataatagc ctgacgtact tttttcatca agttaaccaa gaaataaagg
     5281 ttgtggtagc ttgtcaaacg aataccaaaa gtttcgtccg cttttagcaa gtgacgaatg
     5341 taggcacggc tatagttttg acaagtgtag cagtcacagt catgatcaag tggggtaaaa
     5401 tcttcagcga atttggcatt tttaatcaca agacgcccct cactagtcat gcaagttccg
     5461 ttacgggcga tacgcgttgg caagacacag tcaaacatat ctacaccacg aatcacacca
     5521 tcaatcaagc tatctggtgc tcccactccc atcaggtaac gaggtttatt ttctggtaag
     5581 aggggagtcg taaagtcaag gacggcattc atttcttcat ggctctcccc aacagctaaa
     5641 ccaccaatag aataacctgg gaaatccata gccaccaaat ctgccgcaga ctgacgacga
     5701 aggtcctcaa atccagctcc ttgtacaatt ccaaataatc cttggtcatg aggacgacga
     5761 tgggctttta agccacgttc tgcccaacgg ctagtacgtt caatggattt tttcacgtaa
     5821 tcataaggtt ggtaaaattg cgggcactcg tcaaaactca tcatgatgtc tgagccaagg
     5881 ttattctgaa tggaaatggc tttttcgggt gatagaaaca tttttgagcc attcaagtga
     5941 tttttgaaag tcactccttc ttcagtgatg tttcgtgaat cggctaaaga gtaaacttga
     6001 aaaccacccg aatcggttaa gattggctga tcccagttca taaacttgtg cagaccacca
     6061 gagcgagcaa tcaactcatc tcctggacgc aaccaaaggt gataagtgtt tgataaaata
     6121 atccctgatc caattgcttt taactcttct ggagactgtg ttttaacagt agcctgagtt
     6181 cccactggca taaacattgg tgtcggaaag gtcccgtgag gggtgataat ttcgcccaag
     6241 cgtgcaccgg tgtgcttttc tgttttgata aggcgatact taatcggata atctgtcatg
     6301 tgctttcttc cttgctatca agataaacag tcttgagctt ttttgatctg cctgagtttc
     6361 catcataatg aagggcttca agatgacatg ttgttctagc gcctatcatt ttatcaaaaa
     6421 atccataatt tgtcatgctt tcccaaaaaa gtatagtcaa aataatggtt agctgtctca
     6481 ttttgtttta tggtataatg aaataaagga gtctgttatg tcaattaaag caatcaaagg
     6541 ccaggctaga gacacgttaa aaaatctctc tggcaagtat ttactatttt taattccaac
     6601 ccttctcttt atgtttcatt tcggtattga gattcatcaa ggttacgtcc tatctagtgg
     6661 tattgaagtc tcgctagcgg ctagttattt cccattacta ctaggagtta tccttagcct
     6721 tttcatttta tcagcatcct ttacaatgat tgatgttgtt aggcattttc gtcagaaagt
     6781 ttcttttgcc gaatcaacaa cagccttctc aaaagaattc tttgggaacc tgctggtttt
     6841 agcgatcact aagtggctat tctttctcat ctggtcacta atttggtttt ttggcctctt
     6901 tattttcctt tccggacttt cagcgttttt ggtcaatgct aaatcaggtg gctcaacagt
     6961 catttcactg atctttttac tatttggagc agttttgtcc ttaattggtt ttggtattta
     7021 tatcaaccgt tattacgctt atagtctatc agaatacctt ctctacgata aggttaaaga
     7081 ggggacttat ctaggagcta tagccgtcat tgaaacaagt gtagctatga tgaaaggtta
     7141 taaatggaag ctttttttct tacaacttag cttcaccggt tggtttctac tgaatattgt
     7201 tacttttggg ttacttaata tctatctttt accatatttt acaacagcca atgtcatttt
     7261 ttatgatcaa ctcaagaaac gtttcaaaga caaagatgac ccaattgaag gagaacattt
     7321 aagccttcat cagcttaata aaaagcctac tcctatgatg tatgacgatc aaaaagacta
     7381 aataaatcct ccatccataa aaatagccct tgaactgcac cccaaaagtt agacacaaaa
     7441 tctaacgatt ggggtgctat ttttttatga aatttaatca agaaacgaaa gttaagattt
     7501 atgagttacg gcaaatggga gagtccatta aatccatatc aaaaaagttt gatatggcag
     7561 aatccgatct caaatatatg attcgcttga ttgataggta tggggtaacc attgttcaaa
     7621 aatgtaagaa taattattat tctccagaac tgaagcaaga gataataaat gaagtcctga
     7681 ttgacggcca atctcagaaa caaacatcct tagattatgc tttaccaact tctagtatgc
     7741 tctcaaggtg gatagcgcaa tacaagaaaa acggttatac tattcttgaa aaaccaagag
     7801 ggagaccgag taagatgggg cgtaaacgta agaaaaattt ggaagagatg acagaggttg
     7861 aacgtcttca gaaggaatta gaatacctta gagcggagaa tgctgtgcta aaaaagctga
     7921 gagaataccg cttgagggac gaagtaaagc tcaaagagca acagaaatca ttcaagcatt
     7981 aaggaatcaa tttcccttag agatgctact tgagatcctt gatttatcac gctccaccta
     8041 ttactatcaa gtgaagcgac tagctcaagg agataaggat atagaactaa agcatgtgat
     8101 tcgagagatt tatgatgagc ataaaggtaa ttacggttat cgtcgtattc atatggagtt
     8161 gcgtaaccga ggatttgtgg tcaatcataa gaaggttcaa cgtctcatga aagtcatgag
     8221 cctagcagcc cgcattcgtc ggaagcgcaa gtattcttct tacaaaggag aggttggtaa
     8281 gaaggctgat aatctgatta aacgtcactt cgaaggctct aaaccttacg aaaaatgtta
     8341 cactgatgtg acggagttgg ccttacctga aggaaaactc tacttattac ctgttcttga
     8401 cggctataac agtgagatta ttgatttcac tctgtctcgg tctcctaact tgaaacaggt
     8461 tcaaaccatg cttgagaaga cttttccagc ggattcatac agcggaacta ttcttcatag
     8521 tgaccagggg tggcaatacc aacaccagtc ctaccatgat tttttagagt ctaaaggtat
     8581 tttgccatcc acgtcccgca aagggaatag cccggataac ggcatgatgg attccttctt
     8641 tggcattctc aaatctgaaa tgttttatgg actcgagaca acttatcaat cacttgataa
     8701 gcttgaagaa gctattacag attacatttt ttgctacaac aacaaacgaa ttaaagcaaa
     8761 actaaaagga tttagtcctg tccaatacag aactaaatcc tttcaataat tatttgtcca
     8821 actttttggg gtcagtactg acaggggagg tttcttttta tagtgagctc tgacaataag
     8881 gtgccaggct ttgcaattcc tcaggcgtca ggcgcctaaa ctccccttct gcaaggctag
     8941 ggtctagttt taatggtccc atgctgagac gctgcaagtc aagcactccc tttccacagg
     9001 ctgctaccat gcgtttcacc tgatggaatt ttccttcttg tatggtaatt ttaaccaaac
     9061 ttgttcgctg ctgtaaatca ctagcaagca cttctaaatg agcaggtagg cactggtgat
     9121 cctttaagga aatacctcta gcaaaataat ctttatcagc ttcagtcatg atgcctacta
     9181 ctttagccaa gtactctttc gtaacatgtt ttttagggga taaaaggtca tgggctagtt
     9241 gtccattatt ggtcaagagc aaaagtccac gggtatcctt atctaaccta cccacaggaa
     9301 aaactgcttt ttgcctagcc gtgtcatcta acaactccat aacagtagcc tgctgtctgt
     9361 cctgggttgc tgacacatac cctgacggct tgtttaacag gtaataaaca aaggattcat
     9421 agaccaaggg cgtgccttga tacgtcacca aatccttgta ttcatcaatg tgtgctttgg
     9481 cagaggtttc aaccttttga ttgacgaaaa tagccttctt ttttaagaga agtttgactt
     9541 ggctcctagt tccaacacca gttgccacta aaaatttatc taagcgcatc ataacccttt
     9601 caaagaaaat tcattattaa gtataacata aaaaaacagt agtttcatga ctgtaagcgc
     9661 ttaatatatt ataataggct tatagaaacg aggagattaa cttatgacta tttattctca
     9721 cacttatgaa acccgtccca atcattcggc taaagccatg ggctcaggaa cgctgaatgt
     9781 cctagctact cctgctcttg ttgcttttat ggaaaatgct tcttacttat ttgcccaaga
     9841 acagctcgac agtgacttta caacggttgg cagcgagata gctatccaac atttggcagc
     9901 ttcagccatt ggagatcctg ttacaatcat cattacagcc cttaaagaag aaggccgaaa
     9961 atacgatttc cgcttggaag cttttgtggg agaacaactc attggaaaag cctgtcatac
    10021 tagagttagg gtgaacagta aacattttat ggccaaagta gcggagtaaa acaaaagaaa
    10081 agaaccaaaa aggtaagcaa tccctaagtg cttacctttt tggttatctc aatcaataaa
    10141 atagctttgt gagtgaaagt aactcaaata ctaacaccca tctctttgct aacgcaattg
    10201 ttggtagcgt tctgctttta actgaccaat agaccacata gctccaaaac taatcacata
    10261 cagagaagct aggaaaatca tgaccattga aatacctgag gcatctaaaa tactaccaat
    10321 agcaacggac gaaaatcctc ctagagcacg gccaacattc aaaataacat tattagccgt
    10381 ggatcgaatg tgatggggat aaagtctggt aatcatagcc ccgtagccag caaacatccc
    10441 attgacaaaa aaaccgacaa tagcacctcc aataaccata ctcgccatgg aattggcaaa
    10501 ttgaaaaagg taaacacaaa tagatgatgc taataaaaag agggaataaa tcagacgtgg
    10561 accaaagcaa tctaaaagct gaccaaaaca cagcatcccc aaacacatgc cgacaatagt
    10621 agccaccatc cacaaggacg aactttttac tgaaaggttt aagcttgttt gaataatggt
    10681 tggcaaccaa ttcatcattc caaaatagcc cgcaatctgc acagtcgtca ttaccattaa
    10741 agcaagggtt tgagctgtta aggattttgt tttgaatagt tcattgattt taattggttg
    10801 actgcattct tcctcctctt gcccataatg atcccaaatt ttttggtcat ctatggctaa
    10861 agtcatccaa atcaccaaga gaatcggaag taatccaaag agaaaaaggc cacgccagcc
    10921 tagacttgga gccagccacc ctgctaaaag agccgaacta atggagccaa gctggccagc
    10981 aataccattt aaagaagaca tccgacccat tttttctggt ggtacaatcc ctgccattat
    11041 ggcaatggct acaccgtact cacctccaac tcctatgcca gcaataaatc gcatcaggta
    11101 caggtagggc aaagactggg taaaataaat taatcctgtt gctactgaaa acagtaaaat
    11161 cgtccattta aagaccttaa acttgtggtg cctatcagcc agcaacccga ataagaggcc
    11221 tcccaccaac attcctaaat tggtaatggt cgcaatccag ccaccctgag tgccactaag
    11281 actcaagtct gtcataatgg aagacatgga aaaggcaaga aacatgacat tcaagtcatc
    11341 cgttcctgaa gctgcaatag ctgccactaa agctcgctta tttgtggtgt ccaatgataa
    11401 tgttgacata attgtctcct tcttaatagt agctcactga ctaccttaat taattgaata
    11461 ccctttgtcc aaaggtcaaa aaaagacttg gaaacaagtc cgcaagtcca tcaaagttca
    11521 ctaaataata agagatgaca aaaaaactct ctttaatgtt aagactttca tgcttcacgg
    11581 aacatgttta aagtagtatt taattgttac tagtatagta aagctcattt taattgtcaa
    11641 gttcttttga acatagcgga tacatttttc ttctaagaac caagcctaag tttttttaaa
    11701 aagtcacaaa atgaggtatc cctgcaaaaa accttttctt tcttggaatt tctttgttat
    11761 aatgctttac agaggtgaaa aaatgaaaac tattgctttt gattctaaca agtatttaaa
    11821 cttgcaaaga gatcatattt tagaacgtat cagccaattt gatggcaaac tttacatgga
    11881 atttggtggt aaaatgttag aagattacca tgctgcccgt gtacttcctg gctatgaacc
    11941 tgacaataag attaaattac tcaaagagct caaagaacaa gtcgaaattg taattgccat
    12001 taacgctaat aacattgaac attctaaagc gcgtggtgat ttaggcattt cttatgacca
    12061 agaagtcttt cgcttaattg acaaatttaa cacgttagat atttacgtag gttctgtcgt
    12121 tattacccaa tacaataacc aacccgctgc agatgccttt cgcaagcaac tcaaaaaaaa
    12181 tggcattgct tcttacctgc attatcctat caagagctac ccgacagata ttaatcatat
    12241 tatctcatct gaggggatgg ggaaaaatga ttacatcaaa acgagtcgta accttatcgt
    12301 tgttacagca ccaggccctg ggtctggaaa attagccact tgtatatccc aaatgtatca
    12361 cgaccaaatc aatggggtta agtctggcta tgctaaattt gaaaccttcc cagtttggaa
    12421 tcttcctctt catcaccctg tcaatctggc ttatgaggca gccacggcag acctagatga
    12481 tgtgaatatg attgacccct tccatttgga aacttatggc aaaacggccg ttaattacaa
    12541 ccgtgatatc gaggtctttc ctgtcttaaa tcggaccttc gagcgtattt tgagcaagtc
    12601 tccttatgcc tcaccaaccg atatgggtgt taacatggtt ggtttttcta tcgtcaatga
    12661 agaagctgct atcgaagctt ctaaacaaga aatcatccgt cgttattacc aaaccctcgt
    12721 ggattttaag gcagagcggg tcacagaatc tgctgtcaaa aaaattgagc tcttgatgaa
    12781 tgatatcggt gtcacccctg acgatcgtca cgttactgta gctgctcatc aaaaagcaga
    12841 gcaaacaggc caacctgccc ttgctctcca actaccaaat gggcaaattg tgacaggtaa
    12901 aacatctgaa ctctttggac caactgcagc tgttatcatc aatgcgatta aaaccttggc
    12961 aaagattgat aaaaccactc atttgattga acccgaatac gtgaaaccta ttcaagggct
    13021 caaagtgaac cacttaggca gtcacaatcc gcggcttcat tccaatgaaa ttctgattgc
    13081 gttagccatt actgctatga ctagtgaaga agctaatcta gccatgaaag aactcggcaa
    13141 tttgaaaggt agcgaagccc attctaccgt tatcttaacc gaagaagata aaaatgtact
    13201 ccgaaaactt ggggtaaata ttacttttga ccctgtttac caacatcaca aactttaccg
    13261 taaataaact ataaccaccc gtctaacggg tgatttatgg tatctctcaa taaaggaaaa
    13321 aagtcccaat tctcagagag ttgggacttt tttcctttat tgattcatta atcacccgtt
    13381 atgacgtcgg ccagtcacaa acatggtcaa gcttgttttt gttagaagag ctcctgtttg
    13441 gttatgaatc gtcacatcaa ccacctgcgt ggttcgacct ccatgaacca atcgaccttc
    13501 aaccatcagc ttgtctccct tgtgccctgc ttttaaatag ttagcattgg cctgtaaggt
    13561 gacagattct acgccagtag ttctagcaac caaaccacct acttgatcac atagagtgaa
    13621 aagataacca ccatgagcat tcccatagta attcaaagcc gtctcagtca cttcagtact
    13681 taaaataagg tgtccttttt cagcaagttc aatttggtaa ttatcaaaaa tactaataac
    13741 atttaaggtc atctcttgtg ttaaatctga cattgttttt ctcttttcta agcttagtct
    13801 aaaagcaata caagcctcat tatactacaa ataggaacag aaggcagagc tcatgtttca
    13861 aaaatcagta gcctttccat ccttttctag cgtattgaac acttccaagc ataaatgaag
    13921 cgcaaaacta aaggaatcag cgccccggtt gcgttgatcg taaacctcta catctgctag
    13981 agtatctgct gtaaataaga gttgtcccca aaggatgcct cttaattgag ctactgctgc
    14041 taaggcagaa catcccatct caacaaccga acacccttct tcctggcgat aagccacttt
    14101 ttctttggtt tctcggtaaa aaccatctgt tgaccaggtg atgacctctt gataagctaa
    14161 cccctgtgct gaaagcgttt tctctatcgg tctaagcatc ttaggatcaa tatcaatata
    14221 acaagatggt gccacgtaat gataacttgt tccttcatct cgcaaagcct taactggcac
    14281 taaaaaacgg ttttctgcga taggaaccaa aacgccacag gttcctgtac tgatcatttc
    14341 tttaacccca taaccaatca gccagtccat gaattgcgcc gcaggagctg agccaacggg
    14401 agcttgagct aggcaaatgt cttggccttt ataaggtatc tgataaacag ggtaaacctt
    14461 tgtggctgaa atgaattctg ctactttttt accttgatgg tctaaagcaa aagcttcaat
    14521 ctcgtcttct aagaaagcat agacacactt agctgtagac cttcatgtgt aggtataatg
    14581 acggctgatg gattactatc acattctaaa aggggaatct cgtgtttggt aataggcatt
    14641 cgtttctcct tatttttgtc atgtggaggc agctgcctta ctccttgatt agcaacacta
    14701 cgcactcgac gtgatgggtc tgcgggagtc aaaaggtcca gtggaccttt tgagcgtctc
    14761 accttgaaat aacagagtga ggcggactct ttaactccgt ttctcaagta aacttacaca
    14821 ctcaacttgt tcattattat ccaaacttat attcaagtca tcgtctataa ttgggagctt
    14881 gaaagtaatt gattttagcc attgtccgtt aggttgtttt tcttcataaa cttgaatttc
    14941 agaaatcaaa gctgtaatta actgtctacg ctctacatca ttcatgactt tatagagttt
    15001 atcaaaatag atcagaacct tatatatgtt atctcctgtg agtttttcag cttcaatagt
    15061 ctgtttcttt gctttcgcat caattagtga tgattctaat tcatctattt tgtcatacat
    15121 acgatatagt ctatcatcta aatcctgttt ccttctctta tagtgcttat cttcaacatc
    15181 taaattatct atttcctcaa ttatcttaaa ctttgtagaa tgactcttcc tcaattcctt
    15241 ttggtaatta tctatttctt tttctatttc agaggtgtcc accttcatgt tgattttttc
    15301 ttgcatcata gaagcaaatt tcggattact tacaatcttg acaatcacct ctgcaacagc
    15361 atcatctaac aattcttctc taatttgctt acggaatgta cacttatgac ctcttatcat
    15421 ctgcctatgt ttacaaccat agtaataaaa atctttatac tttgtgccat ctttcttttt
    15481 cttggtacac ttgtttccaa acattcccgc tccacatata gggcatttta caattccaga
    15541 aagcaagtgc gtgcgtgtat cttttccttt attcacatgc tcatatttct ttgcttgaga
    15601 ttttagctta acctgagcag cttgccaaac ttcgtcggaa actatagctt catgtatacc
    15661 ttcagatatt agatattcat cttgttcaac ctgcttatat tcatttcttg taccatgaac
    15721 tttttctaaa gttcttcttc caaatgctat tttcccatta tatacaggat tctttaatat
    15781 ctttcttata agtcctgcat caaacaaagg attctttcca ttctgtcttg ggatttttct
    15841 aattccatga ttctctaagt atttagatag cccattggct cctatcgtag tatttacata
    15901 ctggtcgaaa atcgttctta tggcaactgc ctcttcctca tttataaaca gcttgccatc
    15961 ttcaagttta tatccatacg gagcaaagcc accattccat tttccttccc ttgctttttg
    16021 aatgcgacct tccattgttt gaatacggat gttttctctt tctatttcag ccacagctga
    16081 taaaacagaa atcattagtt tcccagcatc tttagatgaa tcaatgccat cttcaacgca
    16141 gataagatta actccataat cctgcattat ctgaagtgta gaaagaacat cagcggcatt
    16201 tcttgcaaat cttgataact taaacacaag aacaaaagac actccatctt ttccagattt
    16261 tatatcttcc atcattcgat tgaactgttt tctaccttca atagacttgc cagacttccc
    16321 ggcatcttca tactctccga caatttcata atcgttgtaa atagcaaaag ctttcattcg
    16381 tgatttttgt gcctctaacg aatacccctc tatctgtatt gacgtagata ctcgtgtata
    16441 gaggtatact tttatttttt cttttgacat agcattaacc tcattataac tttctatatc
    16501 atatataaac tttgattttt gaatttaagt ttggactatc atttcaagta tattataaca
    16561 cttttattag tccgtctcaa tttgtgtttt tgccttgtca aaactatttt tcatctcttg
    16621 attttttgct ggcgttggat cgggcagatt atctaaatct aaagcaccag catattttgc
    16681 aatcagattt gctattaaat cagccaatcc attccagtca ttgtccaata tatacctcct
    16741 ctctataaag ttttatatct aataattatt tgtttaatta agttttacga cattgacaag
    16801 tgctttggat tagcaacata ggaatctcac ctccgcctct attccggatg agccggcttc
    16861 aaccttagaa gtatcattat cctcattttc ttcatagcgg atagggtatc cctccctata
    16921 ttcaaactct tacttatcgc tctctttctt cttccttttt ttgcttagca gtacttgttt
    16981 tgccgaatta ttcagcagaa agatcttgac ggataggtta ttacgctcca aaaataatta
    17041 acgtcttgtc ttggtctatt caattgttaa ggttcaaaat ttatcgagag ttattaatct
    17101 ttttaaaatt tgaccatcag agaaaattta tcttgatgta acaaaattct ataaattacc
    17161 ctcttatact taacagtgaa aagaagtctt tcttggtaac taattttgaa tagaatttac
    17221 ttatgtaaaa aggtccaatt cccactgcat gagtagcagt gaaaattaga ccctcttggt
    17281 aactgtcatc taaaaatctt ctagcatttc tttaattttc taatcgcctt ttaagtgtca
    17341 tatttacatt tttattatct ctggcatact tttgatacct ttttagactt aaagtcttta
    17401 atagtggctt tccacctctt tttatctata aagattctcc tacatcataa ttcatttttt
    17461 tatttaaact tttctgtctt agtttgtctt tatctttgtc ataccaattt aggattgtcg
    17521 catagtggtt ttgataggtc ttaccactgc tttccatgta tcttgatagt ttatttatca
    17581 ttatttctgt gtgtgagttt agtttttctt taagattttt atattcttct ttgcttaacc
    17641 ttacattttt gaattctcca taaaaaatgg gggtggactt tttatctatc tctccctctc
    17701 tctctttatc tatctctata tctttctcta tctctatctc ttgtcggaca tgggttggac
    17761 tcattaagga caatgtcctc tgtttatttt gtctgtatct tctttttttc tctgcccatg
    17821 ctgtttctga tccgattaag tttggtattt cagttaaata gtattcatca ttttctgtta
    17881 caacttctag taagccttga ttgattaaat aatttactgt gaccattaca tcatcgtctg
    17941 tttcatctat ggttagtgct aactctttta taaaatcact ttctactccg tcataataga
    18001 gtttgccctc atcttttaga cttagtaata aaagttttag gtagattatc gtgtaggtat
    18061 ctcctcccga tattctcctt agtcttttta tccttttgtc tgtgaaaaat tcttctttta
    18121 gttttatcca ataatatctt ttgtttgttg ccatatctgc tcctttcttg attttcgata
    18181 atcgaaattc ttgatttccg attttcggaa ttctggactt ctgcttttcg taagtcttgt
    18241 tattatggtt atttaagggt gtaacttttt gttactccct tagatttctc tggtcatatc
    18301 ttttttgttt ggttttactt tttcttttac tttccttttt actttctctt tcgtcttatt
    18361 cttgttcttg gataggtctt tgtatttctt tatttgtttt aggatacttt ctttttcttt
    18421 tttattttct ttggctatga cttgcttaaa ggcatattcc attactttta tgtctttggc
    18481 ttggaaaaat acttcatagt tttggctttc tttgtttttc attactgaaa agcttactcc
    18541 aagtttgttt agttcttttt ttaagtcttt gaggttgctt tgatctatgc ttatgttttc
    18601 tagttgtcct tttttgtaga ggtcttttat ttttatttca tcgcccataa gactttttag
    18661 gtttccattt gctttttcta aagtatcatt catctttttt cttatttctt tttctaagtt
    18721 gattgattct tttgctgcct ttattgtgta tgatattatg gtttgtgctg cttgacctgc
    18781 ttctttgctt atttcttcgt ttatcatgtt ttctctcctt tgtttgaatt aaaaaaaggg
    18841 aagtataggt tttaattttt ctatacttcc ctttgcttgt ttttaattta ttgtttttgg
    18901 tggtggaatg ctttattttg atgttttcat atcttgttta ggtgtttgta ccttttatac
    18961 ttttaaatag cttacaatac ctttccacct tcagcagttt gtgtgtgttc ttttgtctga
    19021 tagatagttt ttcatgttgg aatatataat ctgtatttct tcattgttca ttgcttttat
    19081 ttcttctgtg cttttgtagg ttttgtatgt tccatcttga tctgctttta tgagttcatc
    19141 tattagctct tgccttttat tcatctctat tacctcctag aacggtcttt attttcttgg
    19201 tcatattata gcttggataa gatattttta ccaggtctta tctttcttga tccattttct
    19261 tgtttttcat actttctctg tattcattat ctttattgac ttggtcttgg aattttttaa
    19321 tctgtgctat tacacttggt ttttctcctt gttttattag cttatctatt tctatggata
    19381 agtctatgcc aagttcttta tttacaaaat ctactgaata ttttatatga ttaatttcct
    19441 ggtattcatc ttttatcttg tctttttctt tatttatttc ttcaagattt accattaaaa
    19501 gatttttttc ttcattccat tttttaggac ttagtttttc cttatctgat aggagttttt
    19561 ttaat
//
LOCUS       DATWVB010000031        19159 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.031, whole genome shotgun sequence.
ACCESSION   DATWVB010000031 DATWVB010000000
VERSION     DATWVB010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19159
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.031"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(643..1077)
                     /locus_tag="VCX65_001270"
     CDS             complement(643..1077)
                     /locus_tag="VCX65_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEP5053730.1"
                     /translation="MTFFPEINIQKTKSNAKRKLREYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLAPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGVLLVEQGVFS"
     gene            complement(1526..2005)
                     /locus_tag="VCX65_001271"
     CDS             complement(1526..2005)
                     /locus_tag="VCX65_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEP5053731.1"
                     /translation="MNIEEAIKKIRELEAFNYFDFKGNLIRRIDVLGIIDQLKIIVQQ
                     CVADWYEKHKDNLEYDLYLYQMSIYDEKVEEDDFYYWMQKSKNPVRTLINMHQFGYEI
                     EQEQLYTVDLPNGQPLVRGKNTLYFSQNLTAENAKLTESEIRKDFEWAWQFAKEVTE"
     gene            complement(2010..2642)
                     /locus_tag="VCX65_001272"
     CDS             complement(2010..2642)
                     /locus_tag="VCX65_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEP5053732.1"
                     /translation="MIKIDEIHRILGIDEVYKAPKRLTDILFDKDSREDIFRQFLKYE
                     TDVSYDWFMQYFEEEQADRKNKKQDFTPKSVSTLLSKIISGNQYYEVAVGTGGILIQA
                     WQEQRLNDSPFTYRPSKYWYHVEELSDKAVPFLLFNMSIRGINGVVVHGDSLTRQVKN
                     IYFLQNTKDDMLSFSDINVMPRTQDIEQEFNVKEWIGDAIVHVESKLNAR"
     gene            complement(2644..2928)
                     /locus_tag="VCX65_001273"
     CDS             complement(2644..2928)
                     /locus_tag="VCX65_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053733.1"
                     /translation="MTIDEALQNLRDNFNKIMNVLKNDWKALLFLAIAIFGMMVTVSY
                     FSYRDARQYYESQITGLRTQLSRTQKQLKRASEDRARQTKRIAEFTHNGG"
     gene            complement(2925..3095)
                     /locus_tag="VCX65_001274"
     CDS             complement(2925..3095)
                     /locus_tag="VCX65_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053734.1"
                     /translation="MKRYIEVKDEWKSATDHLNDFIDKNKYAKVTVVGYQVVQLSPYG
                     RDLTYILAEVEE"
     gene            complement(3092..3328)
                     /locus_tag="VCX65_001275"
     CDS             complement(3092..3328)
                     /locus_tag="VCX65_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEP5053735.1"
                     /translation="MIEELVHKPKHYNHGEIDLIESWYKTYPWDQFVAIMESHIDKYI
                     KRHRYKGNATQDLEKALEYTKRLIEYWLIESVEE"
     gene            complement(3570..3926)
                     /locus_tag="VCX65_001276"
     CDS             complement(3570..3926)
                     /locus_tag="VCX65_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053736.1"
                     /translation="MTLVDDFYKQMEPSIKAFLDDNITIADKEEADRVYRSVKYYKKL
                     NRLPPPDVLEWFQRIYTTKEMIMLIKQSYRLKQKKTDEDDKIYEKWMFKNYGDVKLVK
                     KIKRTDALERARRMGL"
     gene            complement(3910..4260)
                     /locus_tag="VCX65_001277"
     CDS             complement(3910..4260)
                     /locus_tag="VCX65_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEP5053737.1"
                     /translation="MNQRNEKSATSLSEHDIQNLIRMELSQAGHMVFRANVGKVKTAD
                     GRFFDTGLPKGFCDLFGFKPNGQIFFIEVKNETGRIRPEQKKFMEVMASRGALVGVAR
                     SVEDALNIVNDTSR"
     gene            complement(4214..5083)
                     /locus_tag="VCX65_001278"
     CDS             complement(4214..5083)
                     /locus_tag="VCX65_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEP5053738.1"
                     /translation="MYHTTALSFLKKGYQVIPLRKDTGTPMIKFKDIQITEEVIKNTN
                     WFNCDYALLMRGIWCIDIDTHDMDEKLAKELYIMIKKMGIDLLSVLSTDKYDNGLDGY
                     SSIIRHEYKNELISNFKNTFAELTASGGMHILFKKRDGINYTQKIGVMPGVDIKANDN
                     NFVKIFPSDGREVLQAVKTLPYYDGKFEEEAFKPKQEGITTYFGGSVTYTSNGSHEGR
                     EAYERVATGTSYNRNNDLFKGACWAFENGIDIDDLTSIIGTVKGRDVFTREEFELTIE
                     SAKRKVSYVTIRT"
     gene            complement(5352..6905)
                     /locus_tag="VCX65_001279"
     CDS             complement(5352..6905)
                     /locus_tag="VCX65_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage resistance protein"
                     /protein_id="HEP5053739.1"
                     /translation="MTSNEFIEALSKLTTETDWGDPIFGESVLKAELRKHLFKIVPID
                     HNGYIHKLFYSEMVKDEDVMYFVSDGRKTYRFLFGDTILKTDKQGNEYLTYSVENNFP
                     PFAKLVIDYILGAYTFFENKLYDIRYKQFKLIDDFTLQTKYGFKDSGHILEILQGIHK
                     TLNIQPINYIEPYQIACKDFIIDLENSEIINQPPLQNVSYFKYYEVDYKTAINSKSIA
                     EEYLEYVIADSNSLNNAILQSYFIAQVACGVRPKTNFFISKSGVRTGKGLRHIALSGL
                     FNKIDVELDTLKSNGFEALQAWAMFSGGEMALATEQGDIQGNAMERVLKIIATEKTHV
                     ARAIGQNQSMVNLTSVLCIDTNRTVALSDEMNGRKVLIQFKDRPKTETDYERESIFRK
                     YWLAFTDCDKNPKIDGCIGFLLNSLERFQKIGKWYQWKDVEVFNDIDLDEFQVALINA
                     LQEVDFVQRTDNKEVIDLSLQVYGKSNHALSKAISEIGVRSRSKKVNGKTVRGYEIEN
                     KTRFDKYIL"
     gene            complement(6923..7405)
                     /locus_tag="VCX65_001280"
     CDS             complement(6923..7405)
                     /locus_tag="VCX65_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF669 domain-containing protein"
                     /protein_id="HEP5053740.1"
                     /translation="MAGFTTDFSEVKEHAEFKEQPYEMIVYDAYEAVNERNGKKRVVI
                     DYVVRNDIKQEMQNYHLWDEQYPNSQTGKYHIGILMGKAKALGIKEGQHYDSFEAFLN
                     DFKGRTAKVTVKLDEYNGNKYPKVRYANQSDVPNSYHVWKEKATGFTQAEIEEDDLPF
                     "
     gene            complement(7410..8813)
                     /locus_tag="VCX65_001281"
     CDS             complement(7410..8813)
                     /locus_tag="VCX65_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP5053741.1"
                     /translation="MNEARRHILKHNVMIVSPPGSGKSVVISDIAKSATQKNGHVLFL
                     VHRKELIDQITNSFKFHGIDMNKVDLMTVGKAKNRLDKLTKPTLIITDEGHHGKASTY
                     QIIYEYFSDVPRIGFTATPWRLSGDGFTDTYDVMVLGKTVEWLINNNKLAPYDYYSVL
                     SIDTAKLKVQNGDYSNKSIDESFGKKIFGDVVQEYIKKANGQKAILYAHSVEASQAFA
                     KEFQSMGINAIHADAKTPKAKRDKIMKDFRDGKIQVICNVDLISEGFDVPDCTVTILC
                     RPTKSLVLFLQQSMRSMRYQPNKKAIILDHVGNWNIHGLPDTPHHWENYFRGGWKKKS
                     NKTNTVHAKECSVCSALWPLSQQLCELCNHDFGLKEKQEKERIEAELELIKRERFRIK
                     QLANKKFGKDLKTNWEIAQARVKDAGKGKPLYKLIYFYLKTDWVETNVNELAEVTGKS
                     EKEIYSAYNWLKKKLRG"
     gene            complement(8849..9532)
                     /locus_tag="VCX65_001282"
     CDS             complement(8849..9532)
                     /locus_tag="VCX65_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEP5053742.1"
                     /translation="MKITKATEITKTHNWRILIYGKPGNGKTYLTNYLKGKTLILDMD
                     HSSKTIAGNENIDIIQFDRTHPSDFMTEFLTELPELIKEYDNLVIDNITSWQSDWFIE
                     QGRKSKNGITNELQQYNMWTNYYLRVLTTIYSQPTNIFVTAWESTQDLTLESGQIITQ
                     YVPDIRKQVLSQTLGLTDVVGRIQVNPKTGGHGILLQGSDGLYAKNRLDNRTVCKAEE
                     LFNFEGSDA"
     gene            complement(9529..9813)
                     /locus_tag="VCX65_001283"
     CDS             complement(9529..9813)
                     /locus_tag="VCX65_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053743.1"
                     /translation="MRIYVNKKGKPSVEFEFEDRRGGMFDTRLMLKESPLKEEFKADM
                     YKAIDDVLKKYEDIFDTPIFKELIIGKEEDIRKMIDYDDKFTELFGGIRH"
     gene            complement(9810..10004)
                     /locus_tag="VCX65_001284"
     CDS             complement(9810..10004)
                     /locus_tag="VCX65_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053744.1"
                     /translation="MEGMKKYINGQIKLIDTIEECVKEKWPEFDDKKVHKISLAIYQG
                     WSLTDINSTLEAIEMDLDRK"
     gene            complement(10004..10333)
                     /locus_tag="VCX65_001285"
     CDS             complement(10004..10333)
                     /locus_tag="VCX65_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053745.1"
                     /translation="MKTKIEIMRDFFKENPESTQRQASEKLGFTENTVKQYIWRDAKR
                     GYCIKDEEGRVTYLNIEDELSLINEWKSEIRRELIEQLLSANRHETSSEQIRMNAKTI
                     NQILGEI"
     gene            complement(10414..10551)
                     /locus_tag="VCX65_001286"
     CDS             complement(10414..10551)
                     /locus_tag="VCX65_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053746.1"
                     /translation="MKLLDFIFAKPKKQEPIKHDTLRASSEKQWAEFDAYMRKQYGRQ
                     A"
     gene            complement(10548..10844)
                     /locus_tag="VCX65_001287"
     CDS             complement(10548..10844)
                     /locus_tag="VCX65_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053747.1"
                     /translation="MAIEIFGPEFRKKLLEDLIALNMEAIKIAQTKNAKSIEWITMKR
                     LEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGETT"
     gene            complement(10923..11108)
                     /locus_tag="VCX65_001288"
     CDS             complement(10923..11108)
                     /locus_tag="VCX65_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5053748.1"
                     /translation="MWGKIEALLIEKKMTKYELSQKAGLNQNCLIDLKKGRKKSLKFD
                     DVVKIADVLGVSLDEFR"
     gene            11275..11514
                     /locus_tag="VCX65_001289"
     CDS             11275..11514
                     /locus_tag="VCX65_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053749.1"
                     /translation="MDTKEFMKVVSKHINQNFNVDNQLVEFVVAELNQMNAPITQKQA
                     QHIVNILEYVSKSTSKSTIAAMTNALLELGVLKGD"
     gene            11664..11873
                     /locus_tag="VCX65_001290"
     CDS             11664..11873
                     /locus_tag="VCX65_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053750.1"
                     /translation="MNLEELTPLLNSIDDFETVILHSLVGDFVIDHWIEPNRKNETLI
                     FMHNDQTTELKLSAILGTSTIPKSL"
     gene            12132..12641
                     /locus_tag="VCX65_001291"
     CDS             12132..12641
                     /locus_tag="VCX65_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053751.1"
                     /translation="MELFNTIIGVIALIVAVIALVHSIYYNMVKIKLSDCYISRVDKG
                     YDWMYDFSISNLSNVSVIIKKIELYNKDGKLISDNGFNPFQKYEADMQNEADDYYGLS
                     MPNYYMPLDYQWESSPFKSDTEVYPSSRENFSYYLDEKPVKIKITTDKRIHQFRKYQL
                     FFPHFDNNS"
     gene            complement(12749..12976)
                     /locus_tag="VCX65_001292"
     CDS             complement(12749..12976)
                     /locus_tag="VCX65_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEP5053752.1"
                     /translation="MTKKQRLKQEHLKPKKRLREERLKREYTKMYMADLIGLKNRKGY
                     SEKEDGLQPFKDYEMAIISQKFNVSESELFF"
     gene            13050..13436
                     /locus_tag="VCX65_001293"
     CDS             13050..13436
                     /locus_tag="VCX65_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053753.1"
                     /translation="MFDYFKLYIIVLETFVETKPDDAYSLFDNLSLNSEFVKFSKDLD
                     KNIVISGTLEVIDNLLDDCLIKGKRRPTKDITFYFFDGVTTTGYLYLQSLKDNNFSSR
                     LKNVLKEEGIPLTPTSITRTIAKLTL"
     gene            complement(13425..13634)
                     /locus_tag="VCX65_001294"
     CDS             complement(13425..13634)
                     /locus_tag="VCX65_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053754.1"
                     /translation="MRPKKYPYSQKNYPAPKLHNVIETDNQFLIDDKRIHYVIEDSVK
                     TKTLGDGYVEVTLSIIAKSFTKSQG"
     gene            13688..14287
                     /locus_tag="VCX65_001295"
     CDS             13688..14287
                     /locus_tag="VCX65_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053755.1"
                     /translation="MDLLKNTNFLIPLISAIVSVSSIFISNWLGYRSQIRKLKFDEEK
                     EIYLTLYVPLIKWMNSQSFNNKSYYWLVAFPRYTTNAQDFLTGLLLKNFEKLPVSVAM
                     RYSEYTLNSATSLHFYRNTEYDYDYETFAKKASELFDLIIEQLLTEGTILSQKLSLPN
                     LSKSTLENFLADKKNYIGPRFLSLETHNKPLRPERPLPF"
     gene            complement(14317..14475)
                     /locus_tag="VCX65_001296"
     CDS             complement(14317..14475)
                     /locus_tag="VCX65_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053756.1"
                     /translation="MNWKKLMFGDLEYTFASRDGKEKTSIEFEGGLLPALLVLGGITW
                     LAAWFITK"
     gene            14534..14749
                     /locus_tag="VCX65_001297"
     CDS             14534..14749
                     /locus_tag="VCX65_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053757.1"
                     /translation="MKISNSKDLALAIVASSSPTLSIEDKIKLYEDSVEAIKKHNLPF
                     VEAEKQEQINNGKVIAEALERGESLFG"
     gene            complement(14735..14884)
                     /locus_tag="VCX65_001298"
     CDS             complement(14735..14884)
                     /locus_tag="VCX65_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053758.1"
                     /translation="MRERNEKFIGVLKDMHMQILRDFTNEEDPLTRCELAKGFLEIGD
                     YLSKQ"
     gene            15242..15985
                     /locus_tag="VCX65_001299"
     CDS             15242..15985
                     /locus_tag="VCX65_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP5053759.1"
                     /translation="MNILGNSIKEIRKSKKMTQKELAKLTGFKQNTISNHENGNRQLD
                     EVDIRKYAKALKIEPQQLFDYSSSPTNPQVELIPSTLQKINSTSSQLEHSRQIIVLDT
                     AETLLEQQKEIKNNEDTIAELFSYNYYDHAASAGTGQYLNDVQVEKIELPVDYDADFV
                     IPVYGDSMEPKYHSGDYVFVKLSVELTDGDIGVFEYYGDAYIKQLLINAEGAFLHSLN
                     QCGDYPDIPIDRDSDFRIIGEVMGSYRER"
     gene            15998..16807
                     /locus_tag="VCX65_001300"
     CDS             15998..16807
                     /locus_tag="VCX65_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HEP5053760.1"
                     /translation="MDSKALNKQNLSRSKKILLNISDNPKNPKFYKLSRQELERAKIF
                     KTENLIKSQKYQRYKRGTIVFIHFGVNIGNEFSDSHFGIVLNKKDHPNNGKLTILPLT
                     SKNSKESLSINKEIFTSIMDDAEKTVQTVQNVLNLTTEVERIHHSLPVPPAFFQIKKE
                     NKYHDIWMKYYNRHDPKGIHVPVANITVRKWIQSDLDKINFLKKRYANYDKVSYAKLD
                     SITSVSKLKIAKPINDLDPVGKITLSKEIMDNIDKALARQLLSGQWGKLDN"
     gene            17057..18145
                     /locus_tag="VCX65_001301"
     CDS             17057..18145
                     /locus_tag="VCX65_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEP5053761.1"
                     /translation="MKIKSYKKENGETAYKFLLYAGYVNGKRKYIRREGFKTKQAARE
                     TLISLQAELDKPKSSMTFGVLTKQWLNEYEKTVQGSTYLKTERNINKHILPKLDKVKI
                     GDINPLLIQRLTEEWCNDLKYGGKILGLVRNILNLAVRYGYINNNPALPITPPKIKRR
                     RKMNNNFYTLDQLKQFLELVEKTDNIEKIALFRLLAFTGIRKGELLALTWDDLNGNTL
                     SINKAVTRTQVGLEIDVTKTKSSDRLISLDDETLEILQELHETFPTSTLMFQSESGGI
                     MTPSLPRKWLLQIIKGTDLPQITIHGFRHTHASLLFESGLSLKQVQHRLGHGDLQTTM
                     NVYTHITQSAIDDIGTKFNQFVTNKQLD"
     gene            18508..19128
                     /locus_tag="VCX65_001302"
     CDS             18508..19128
                     /locus_tag="VCX65_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEP5053762.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
BASE COUNT         5756 a         3723 c         3021 g         6659 t
ORIGIN      
        1 tttaaattag attctttaga agaacttaat ttaaagaaac ttgcttttgc gggtttgttt
       61 tccatattta atctccatat tttttatcac ttcaataata caacgaaaaa agcccttaca
      121 caataggtat aataggcttt tttaataaaa atatggagtt tgcattaaat gcaacaggaa
      181 cagtcggaat cgaaccgaca catcttcttc tggctcttcg caaagagttt tcggacttag
      241 ctaacgtccc gaagcaaggc gctacctcca ccgttttcca atcacggttc atgttcctaa
      301 caggctttgc acgaatcgaa cgtgcataaa cgaccattaa gcctactaac cacaagcaag
      361 gttgcgaccc ttgttttact tgcggttaat cataaaaccc cacacatcag atcgtgtcta
      421 cctttaaatg ggtgtggggt cgcgtctccc ctgacgctga tagagacggc aggattcgaa
      481 cctgcacgtc ccacatacca taaaataaca agtttgatcg tagttaaagt tggcgactaa
      541 ataaaatagt cagtgattaa aaggttatct cttcttgtta ttttgatagt actataataa
      601 catgtaaaaa tatgtataaa ctatcttatt actgtataaa aactagctaa aaactccttg
      661 ctcaacaagc aacacaccct ctctgtacag ctctgcaaaa gctaacaaag caatgtcaag
      721 tgtatcatag taaaagctct ctgacataca caattctgta taaataacct tatctgcctt
      781 tttataaggc gctaaatatt tgtcatacaa aatcctgcgt ctctctggct ctagtatcat
      841 actgacggct tgctcaatcg catccagctc ttgttctgct gacacacggt ttagcgctag
      901 tctctcaact ggtttactag ggaccccatg cggttgcctt ggctcaaatg agtaagtagc
      961 tgtaactttt tgagtatcta cgtcattagc tatccttcgc cagcgtggat actctcttag
     1021 ttttcgctta gcgtttgatt tagttttttg tatattaatt tctggaaaaa acgtcatgaa
     1081 agcccccgat gtggtataat ttatttaagc ttaaatttaa ccaagggggc gttccgtgtg
     1141 gacgtctttt tgttttgtgg agaaaagccc tctctttcct ttgttttttg acacaggcgc
     1201 acgatgtcgt gttaaagcat tagcgacgcc ttggataatc acggatgacc gataacccgc
     1261 tttagatttg ttttggtgta aggaggttct cgtttctatt ttttaatttc ggtccacccc
     1321 cacagagcca tcgcaggctc ttgagcgctt gcgtggggtt ataattttgt cagcgatacc
     1381 catttaaact gtggaaactg ttctgcttgt ttgcgggtgc atttagtagc ctgatgtgga
     1441 ttatcaacat aagatatata cctgcaagtt ttatataaat aatacttatg ccatttttcg
     1501 ctatataaca ctcctaactc ttcagtcatt cagtcacctc tttcgcaaat tgccaagccc
     1561 actcgaagtc ttttcggatt tctgattcag tgagttttgc attttcggct gttagatttt
     1621 gactaaaata caaagtgttt ttaccgcgta ctaaaggctg accgtttggc aaatcaactg
     1681 tatacagctg ctcttgctcg atttcatagc caaattggtg catattaata agagtacgaa
     1741 ctggattctt tgatttttgc atccaataat aaaaatcatc ttcttcaact ttttcatcat
     1801 agattgacat ttgatataaa tataaatcat attccaaatt atctttatgc ttttcgtacc
     1861 aatctgcaac acattgttgt actataattt ttagttggtc gatgatacct aatacatcaa
     1921 ttcttctaat taaattacct ttaaagtcga aataattaaa cgcctctagt tctcttatct
     1981 ttttaatagc ttcttcaatg ttcattttgt tacctcgcat ttaacttact ctctacatgc
     2041 actatcgcat caccaatcca ctctttgaca ttaaattctt gctcaatatc ttgagtcctt
     2101 ggcataacgt taatatcact aaaactcagc atgtcgtctt ttgtattttg caaaaaataa
     2161 atgtttttaa cttgtcttgt taaagagtca ccatgcacca ccacaccatt tatccctctt
     2221 atagacatat taaagagtag aaacggtact gctttgtccg ataactcttc tacgtgatac
     2281 cagtatttac tcggacgata agtaaatgga ctgtcattta atcgttgttc ttgccatgct
     2341 tggataagta tcccacccgt cccgactgct acctcgtagt attgattacc acttattatt
     2401 ttagataata gtgtactaac cgatttaggc gtaaagtctt gctttttatt tttgcggtca
     2461 gcttgttctt cctcaaaata ttgcataaac cagtcgtaag atacatctgt ttcatatttc
     2521 aaaaactgtc taaatatatc ctcacgacta tctttatcaa agagtatgtc cgtaagtcgt
     2581 ttgggtgctt tataaacttc gtcgatgcct agtatgcgat gtatctcatc gatcttaatc
     2641 atgttaccct ccgttgtgcg taaattccgc aattcgcttt gtctgtctag ctctatcttc
     2701 gctagcacgt ttaagctgct tttgtgtcct gcttagctgt gtacgtagtc ctgtgatttg
     2761 cgactcgtaa tattgtcgtg cgtcgcgata gctaaaatac gacacggtta ccatcatccc
     2821 aaatattgcg attgcaagaa acaatagtgc tttccaatcg ttttttagga cattcattat
     2881 tttattaaag ttatcacgta aattttgcaa cgcttcatct attgtcattc ttccacctct
     2941 gccaaaatat aagtcaaatc tcttccgtaa ggagaaagtt gtacgacttg ataaccaaca
     3001 actgtcactt ttgcgtactt gtttttgtcg ataaaatcgt tcaggtggtc tgttgcactt
     3061 ttccattcgt ccttaacttc aatatatctc ttcattcttc cacgctttcg attaaccaat
     3121 attcaatgag acgctttgta tattcgagtg ctttttctaa atcctgagtc gcattgcctt
     3181 tgtatctatg tcgtttaatg tatttatcaa tgtgactttc catgattgcg acaaactggt
     3241 cccatgggta cgtcttatac cacgactcaa tcaaatcaat ttctccgtga ttataatgct
     3301 ttggtttatg tactaattct tctatcatca ctccacctct ctcaaaaaat ttataatcaa
     3361 tttacactcg ctctcatttg gcaatattct gcgttctaag agcgctttta attgccaagt
     3421 ataaatgcct atcttatctg ctaaaacgtc atcagacatc tttattttgc atctgtgagc
     3481 tattaacagc tctgatatat cgtaaggcaa cagattatcg taagatctag gtgtatattt
     3541 aatatcgtta tgccactgtc tgtgtctttt catagaccca ttctccgagc tctttctagt
     3601 gcgtccgtgc gtttgatttt tttaacgagc ttaacgtcac cgtagttttt aaacatccac
     3661 ttttcgtaaa tcttgtcatc ctcatctgtc tttttttgtt taaggcggta agactgcttg
     3721 attaacatta tcatttcctt tgtcgtgtaa attcgttgga accactccaa tacatcaggt
     3781 ggcggcaatc tgtttagttt tttatagtat ttgacagatc tatagactct gtcagcttct
     3841 tctttgtctg cgatggtaat gttatcgtct aaaaacgctt taattgacgg ctccatttgt
     3901 ttgtaaaaat catctactag tgtcattgac tatgtttaag gcatcttcca ctgaccgagc
     3961 cactcctaca agcgctcctc tagatgccat gacctccata aattttttct gttctggtct
     4021 tatccgacct gtttcatttt taacttcgat aaaaaatatt tgtccgtttg gtttaaatcc
     4081 aaacaaatca caaaaacctt ttggtaaacc tgtatcaaaa aatctaccat ctgctgtttt
     4141 cacctttccg acatttgctc gaaataccat atgccccgct tgtgataatt ccattcggat
     4201 aaggttttgg atatcatgtt ctgatagtga cgtagctgac ttttcgtttc gctgattcaa
     4261 tcgttaattc aaactcctct ctcgtaaata cgtctctgcc tttaaccgtc ccaataattg
     4321 atgttaaatc atcaatatcg ataccatttt caaacgccca acacgctcct ttaaacaaat
     4381 cattattcct gttatatgat gttccagttg ctacacgttc ataagcctct cggccttcgt
     4441 gacttccgtt tgatgtatat gtgacagaac ctccaaaata ggttgttata ccttcttgtt
     4501 ttggtttaaa tgcttcctct tcaaattttc catcataata aggtaatgtt ttaactgctt
     4561 gtaaaacttc acgtccgtca gatgggaata ttttgacaaa attattatca ttcgctttta
     4621 tgtcaacacc aggcattact cctatttttt gcgtgtaatt aataccatcg cgttttttaa
     4681 agagtatgtg cataccacca cttgcagtta attctgcgaa tgtattttta aaattactga
     4741 ttaattcgtt tttatactca tgcctaataa ttgacgaata accatctagt ccattgtcat
     4801 acttatcagt cgataataca gataataaat caatccccat cttttttatc attatgtata
     4861 actctttagc taacttctcg tccatgtcat gagtatcaat atcaatacac caaatgccac
     4921 gcattaataa agcataatca caattaaacc agtttgtatt tttgatcact tcttccgtta
     4981 tttggatatc tttaaactta atcattggcg ttccagtatc ttttctaagc ggtataacct
     5041 gatatccttt ttttaagaat gaaagtgctg ttgtgtggta cataaggtaa cgcaccccct
     5101 tttttactac gtaacctcta aaacgttgat atagatagca ttagagaagg atggttacgc
     5161 agtaacgcaa aatcacccta ccctacccct atatataaat aaataattaa taaatcatta
     5221 attagactta ttgtttgtta ctgcgtaacc tttcttaaat aaatgctgaa atcgattggt
     5281 actaaagaga ttgagtaggt tacgcaacat ggaaaattct gcgtaacttt gcgtgaccat
     5341 gcgttacctt tttaaaggat atatttatca aaacgtgttt tattttcgat ttcataccct
     5401 ctgactgttt tcccgttaac tttcttcgac ctgctacgta caccaatttc agatatggct
     5461 ttacttaatg catgattgct ttttccgtaa acttgtaatg ataagtcaat aacttctttg
     5521 ttatcagttc gctgtacaaa atcaacttct tgtaatgcat ttattaaagc aacttgaaat
     5581 tcgtctaaat cgatatcatt aaatacttca acatctttcc attgatacca tttaccaatt
     5641 ttttggaaac gctcgagtga atttagcaga aaaccgatac atccatcgat ttttggattt
     5701 ttatcacagt cagtaaatgc tagccaatat ttcctgaata tgctctctct ttcataatca
     5761 gtttcagttt ttggtctatc tttaaactga attaaaacct ttcgtccatt catttcatcc
     5821 gacagcgcaa cagtacggtt ggtgtcaata cacagaacac tcgttaaatt aaccattgac
     5881 tgattttgcc caattgctcg tgcaacgtgt gttttctctg ttgcaataat tttaagtaca
     5941 cgctccattg cattgccttg aatatctccc tgttccgtcg ctagagccat ttctccaccc
     6001 gagaacatcg cccacgcctg taacgcttca aatccattac tttttaatgt atctagctca
     6061 acatcaatct tattgaatag accagataaa gctatatgcc ttaacccttt accagtcctt
     6121 actccagatt ttgagatgaa gaagttggtt ttaggtctaa caccacacgc tacttgggcg
     6181 ataaaataag attgtagtat tgcattgttt aacgaattgc tatctgcaat aacgtactca
     6241 agatattctt ctgcaataga cttactgttt attgctgttt tgtagtctac ttcgtaatac
     6301 ttaaaataag atacgttttg caaaggcggt tggttaatga tttcagaatt ttcaaggtcg
     6361 attatgaaat ccttgcaagc aatctgatat ggttcaatat aattgattgg ttggatgttt
     6421 aatgttttgt ggataccttg tagtatctct aaaatgtgac cagagtcttt gaaaccatac
     6481 ttagtctgaa gtgtaaaatc atcaatcaat ttaaattgct tatatcgaat gtcataaagt
     6541 ttattctcaa aaaacgtgta agcacctaga atgtagtcga taactagttt tgcaaatggt
     6601 ggaaaattat tttcaacgga gtatgtgaga tattcattgc cttgtttatc agtctttaga
     6661 attgtatctc caaataaaaa gcgataagtt tttcgtccat ctgacacaaa atacatgaca
     6721 tcttcatctt taaccatttc tgaataaaac agtttgtgga tatacccatt gtgatcaatt
     6781 gggacaattt taaataagtg ttttcgtaat tcagctttaa gcactgactc gccgaagatt
     6841 gggtctcccc aatcggtttc ggttgtcaat tttgataaag cttcaataaa ttcatttgat
     6901 gtcatttatc ccccagtcta aattagaacg gtagatcgtc ttcttcaatc tccgcttgtg
     6961 taaatccagt tgctttttct ttccatacgt ggtagctgtt aggcacatcg ctttgatttg
     7021 cgtaacgaac tttcgggtat ttatttccgt tatattcgtc aagtttaacg gttacttttg
     7081 cagtgcgtcc tttgaagtcg tttaaaaacg cttcaaaact atcgtagtgt tgcccctctt
     7141 tgataccaag tgcttttgct ttacccatta agatgccgat atgatacttc ccagtttgtg
     7201 agttgggata ttgctcatcc cataagtggt agttttgcat ttcttgcttg atatcgtttc
     7261 gaacaacgta gtcaataaca acacgttttt tgccgttacg ttcatttact gcttcatatg
     7321 catcatagac aatcatttcg tatggttgtt ctttgaattc tgcgtgttct ttaacttctg
     7381 aaaaatctgt tgtaaatcct gccatgtttt tatcctctta atttcttttt tagccaattg
     7441 taggcgctat atatttcttt ttctgacttg cctgttactt cggcaagttc attaacgttt
     7501 gtttctaccc aatcagtttt taagtagaaa tagataagtt tatataatgg ttttccttta
     7561 ccagcgtctt taactctagc ttgggcaatt tcccagtttg tttttaaatc tttaccaaac
     7621 ttcttattag caagttgttt gattctaaac cgctcacgtt ttatgagttc aagttctgcc
     7681 tctatgcgtt ctttctcttg tttttctttc aatccaaaat catgattgca taattcacag
     7741 agctgttgac taagtggcca caaagccgaa cacacagaac attcttttgc gtgtaccgtg
     7801 ttagttttat tcgacttctt cttccaccct cctcggaaat aattctccca atgatgcggt
     7861 gtgtcaggta agccgtgaat attccaattt cctacgtgat ctaaaatgat ggctttttta
     7921 ttaggttgat atctcatcga ccgcatagat tgttgcaaaa ataatactaa tgattttgta
     7981 ggtctacaaa gaatagttac tgtacaatct gggacatcga aaccttctga tatcaaatca
     8041 acgttacaga taacttgtat cttaccgtca cggaaatctt tcatgatttt atcccgtttg
     8101 gctttaggcg tttttgcatc tgcgtgtatt gcattaattc ccatagattg gaattcttta
     8161 gcaaatgcct gcgatgcttc taccgagtga gcgtataaaa tagctttctg accgttcgct
     8221 ttttttatat attcttgaac tacatcacca aaaatctttt taccaaatga ttcgtcaatc
     8281 gatttattgg agtaatctcc gttttgtact tttaatttcg cagtatcaat tgatagaaca
     8341 ctgtaataat catatggtgc aagtttatta ttattgataa gccactcgac cgttttacca
     8401 agaaccataa catcgtaagt gtctgtaaaa ccgtcgcctg atagacgcca aggtgtggca
     8461 gtaaaaccaa tcctcggcac gtctgaaaag tattcataga ttatttggta ggtactagct
     8521 ttcccatgat gaccctcatc tgtgataatt aaggttggtt ttgttaattt atccaagcgg
     8581 tttttagctt taccaactgt cattaaatcc actttattca tgtcaattcc atggaattta
     8641 aaactattag tgatttggtc aattaattct ttgcgatgga ccaagaataa aacgtgtccg
     8701 tttttttgag tcgctgactt agcaatatca gaaatgacta ctgacttacc acttccaggt
     8761 ggactaacaa tcatcacatt atgctttaaa atatgtcttc ttgcctcatt tataagttct
     8821 gtttgatatt cgtgtaaatg gtataccgtt acgcatcact cccttcgaaa ttaaacaact
     8881 cttccgcctt acaaacggtc ctattatcaa gcctattttt tgcatatagt ccgtcgctgc
     8941 cctgcaacaa aattccatgc ccgcccgttt ttggatttac ttgaatacgt ccgacaacat
     9001 cggttaaacc tagcgtttgg cttaggactt gtttgcggat atctggcacg tattgcgtga
     9061 taatttgtcc gctctcgagc gttaaatctt gcgttgattc ccaagcagtc acaaaaatat
     9121 tagtaggttg gctgtaaatg gtagtcaata ctcgtaaata gtaattggtc cacatgttgt
     9181 attgttgcaa ttcgtttgtg attccatttt tggatttacg accttgttcg ataaaccagt
     9241 ctgattgcca acttgttata ttatcaatga ctaaattgtc atattctttg ataagttctg
     9301 gtagttctgt caagaattcg gtcataaagt cgctagggtg cgtcctgtca aattggataa
     9361 tatcaatgtt ttcgtttccg gcaatcgttt tagacgaatg gtccatgtct aaaatcagtg
     9421 tcttgccttt taaataatta gttaagtaag ttttcccgtt tccgggttta ccatagatta
     9481 atatgcgcca attatgggtt tttgtaattt ctgtcgcttt agtaatcttc aatgtctaat
     9541 ccctccaaaa agttcggtaa atttatcatc gtaatcaatc atttttctaa tatcttcttc
     9601 tttcccaatt attaattctt taaaaatagg agtatcaaaa atgtcttcgt atttttttaa
     9661 aacatcatca attgccttgt acatatcggc tttaaattct tctttgagtg gtgattcttt
     9721 taacattaat cttgtatcaa acatgccacc gcgtcgatct tcaaactcaa attcaacaga
     9781 tggtttacct tttttgttta cataaattct cattttctat ccaagtccat ttctatcgct
     9841 tcgagtgtgc tattaatatc tgtaagggac catccttggt aaatagctaa agatatctta
     9901 tgtacttttt tatcatcaaa ttcaggccat ttttctttga cacattcttc aatagtatca
     9961 attagtttaa tctgaccatt gatatacttt ttcatacctt ccattaaatt tctcctaaaa
    10021 tctgattgat tgttttagcg ttcatacgaa tttgttcgct tgacgtttca tgtcgattag
    10081 ctgatagtaa ctgttcaatc aattctcttc taatttcact tttccattca ttaataagcg
    10141 ataattcatc ttcaatgttt agataagtta cacgaccttc ttcgtcttta atacagtagc
    10201 cacgcttagc atctctccaa atatattgtt taactgtatt ttccgtaaat ccaagctttt
    10261 ctgaggcttg ccgttgagtt gattcaggat tttctttaaa aaaatcacgc atgatttcaa
    10321 tttttgtttt catttaaaat gacctccata tcctctaaat acttgctatc atcaccattt
    10381 gtgcggtagt ttcgcatggc tatcaatatc tgattaagct tgtcgtccat actgtttcct
    10441 catataggca tcaaattcgg cccactgctt ttcagatgat gctctaagcg tgtcgtgctt
    10501 aatcggttcc tgtttttttg gttttgcaaa aataaaatct aataatttca tgttgtttct
    10561 cctttttcat atccactggt ccgtaaaaat ctattaacat ctgctaggtc atatagtact
    10621 ttcccgtttt ctgatgacct tttaaagtta aatttccctt gttctctcca ctgggtcaat
    10681 ttagttcgcc cccatccagt ttctttttct agccgcttca tggttatcca ttcaatagac
    10741 ttggcgtttt tggtctgcgc tatttttatc gcttccatat ttagagcgat taaatcttca
    10801 agcagttttt ttctaaactc aggtccaaat atttcaatgg ccatagtttt tccctctctc
    10861 ttatgttata attaagtaaa ttaaaatttg ttttgagtcc gattgccgtc ggactttttt
    10921 tgttatctaa attcgtctaa gctgacacct aagacatcgg caattttaac gacatcatca
    10981 aatttcaatg atttttttct tcctttcttt agatcaatca agcaattttg gttcaatcca
    11041 gccttttgtg acagttcata tttggtcatt tttttctcaa ttaatagagc ttcgatttta
    11101 ccccacataa ttcctcctaa gcacaacatg tagttgttga taacttttta tatacaatat
    11161 attgattttt caatatagtc ttgatataat attcgtatga ttcaacaaga tctctcgaga
    11221 gacctctact cttctaatct tgtttagtca aataagcaag aaaggagatt aattatggat
    11281 acaaaagaat ttatgaaagt tgtctcaaaa catatcaacc aaaatttcaa tgttgacaac
    11341 caattagttg aatttgtcgt tgcggaactt aatcaaatga atgcacctat tacacaaaag
    11401 caagctcagc atatcgttaa tattttggag tatgtctcta agtcaacctc taaatctact
    11461 atcgcagcta tgacaaatgc attgttagag cttggcgtac ttaagggaga ttgatgcaat
    11521 caactttacc ggtttttatc agttcagggt ctatcttatg ataggctctc tttttctctc
    11581 cgctatacgg atatcgtttt ggtctcatgt gcttcctttc tgttgtataa tgtagttatc
    11641 ctattaggaa ggagggtaac taaatgaatt tagaagaatt aactcctcta ttgaatagta
    11701 ttgatgattt tgaaactgtt attttacata gtcttgtcgg agactttgtt attgatcatt
    11761 ggattgagcc taatcgcaaa aatgaaactc tcattttcat gcacaatgac caaacaacag
    11821 aattaaaatt atcagctatt ctcggaactt ccactattcc taagtccctc tagcaaattg
    11881 cggacttttt cggaacgttt acctgcatat tttgattttc cgagtctcca acttagtagg
    11941 cgatgttcct cttctgataa gtaacctgct ctttgtagca ggttttttgc tatcttccat
    12001 ggaatcacta catctacttc atccatgttt attaccattt cttcaagttc ttctagtttg
    12061 ttttctattt cgttcatatg tgtcctttct attttggtat aattaaaata aaaacgattg
    12121 gaagaataaa aatggaatta tttaatacaa ttatcggcgt cattgcgcta attgttgctg
    12181 tgattgctct tgttcactct atctactaca acatggttaa gataaaatta tctgattgtt
    12241 acatttcaag agtagataaa ggttacgatt ggatgtatga ttttagtatc agtaacttat
    12301 cgaatgtttc agtcattatt aaaaaaattg aactttacaa caaagatgga aaactaataa
    12361 gcgataatgg cttcaatccc tttcaaaaat acgaagctga catgcagaat gaagctgatg
    12421 attattatgg attgtcaatg ccgaattatt atatgccatt agattaccaa tgggagtcat
    12481 cgccatttaa gtcagatact gaagtatatc catctagtcg agaaaatttc tcttactatt
    12541 tagatgaaaa gccagttaaa atcaaaatca caactgataa gcgtattcat caattccgaa
    12601 aatatcagtt attctttccc cattttgaca ataatagtta agatagcgat attcgttaat
    12661 aaaattaaga taagtgctgc cgttaggagc atttttcttt tatcctttct agtgttgtac
    12721 actttatctc gttttgagat atttttgttt aaaaaaataa ttcactctct gaaacattaa
    12781 atttttgaga aatgatagcc atttcataat ctttaaaagg ctgtaaacca tcttctttct
    12841 cagagtaacc ttttctattt tttaaaccaa ttaaatcagc catatacatt tttgtgtact
    12901 cacgttttaa acgttcttct cttaaacgct ttttaggttt gagatgttcc tgttttaaac
    12961 gttgtttttt cgtcattccc ccacctcctt tctatctgtt tttagttcct ccaatctgct
    13021 ataatatggg cagaaaggag gtgaatgtga tgtttgacta tttcaaactt tatataattg
    13081 tcttggaaac cttcgtggaa accaaaccag acgacgctta tagcttattt gataatctaa
    13141 gtcttaacag tgaatttgta aaattctcta aagacttaga taaaaacatt gtaatatcag
    13201 gcactttaga agtaattgat aatttacttg atgattgctt gataaaagga aaacgtcgcc
    13261 caacaaaaga tattactttc tattttttcg atggcgtaac aacaactggt tacttatatc
    13321 ttcaaagtct taaagataat aatttttcga gccgtttaaa gaatgtcctt aaagaagaag
    13381 gtatccctct tacaccaact tctatcacaa ggactatcgc caaactaacc ttgtgatttt
    13441 gtaaaactct tggcaattat ggaaagtgtt acttcaacat agccatcgcc aagggttttt
    13501 gtctttacag aatcttcaat aacataatga atccttttat catctattaa gaactgatta
    13561 tcggtttcaa tgacgttatg aagcttcggc gctggataat ttttttggct atacggatat
    13621 tttttggggc gcatctattc cacccccttt ctgtggtata atttaaataa aatgattgga
    13681 gaaaatcatg gatttattga aaaataccaa ttttttaatt ccgttaattt cagcaatagt
    13741 ctctgtttct tctattttta taagcaattg gcttggttat agaagtcaaa tcaggaaatt
    13801 aaaatttgat gaagaaaaag aaatatacct aaccctctat gtaccgttaa taaaatggat
    13861 gaattcgcaa tcattcaata acaaaagtta ttattggcta gtggcgttcc ctagatatac
    13921 aacaaatgca caagattttc tgacaggctt gttgttaaaa aattttgaaa aattaccagt
    13981 atcagttgct atgagatact ctgaatacac cctaaattct gcaacctctt tacattttta
    14041 tcgtaacacc gaatacgatt atgattatga aacatttgcc aaaaaagcat ctgaattatt
    14101 tgatctcatt attgaacaat tgctaacaga agggacaata ttatcccaaa agctaagctt
    14161 accaaactta tccaaatcca ctttagagaa ctttttggcg gacaagaaaa actatatcgg
    14221 tcccagattt ttatcactag aaacccataa caaaccccta agacctgaaa gaccactgcc
    14281 attttaactc ccccctttcc gccccttgtg ggctttttat tttgtaataa accaagctgc
    14341 taaccaagtg ataccaccta acaccaacag cgctggcaat aagccacctt caaattcgat
    14401 gcttgttttt tctttgccgt cacgactggc aaacgtgtat tctaaatcgc caaacattag
    14461 ttttttccaa ttcattttgt gcctcctaaa aatgttataa tcaacttatc ctagcggaaa
    14521 ggaggataag ctaatgaaaa tttctaattc aaaagattta gctctcgcta ttgtcgcttc
    14581 ttctagccct actttgtcta tcgaagataa aatcaaactt tacgaagact ctgtggaagc
    14641 tattaagaaa cataatttac ctttcgttga agccgaaaag caggaacaaa tcaataatgg
    14701 taaagttata gccgaagctc ttgagcgtgg cgagtcattg tttggataaa tagtcaccaa
    14761 tttcgaggaa ccctttagca agctcgcacc ttgttaaggg gtcttcttcg tttgtgaagt
    14821 ctcgcaaaat ttgcatatgc atatctttta gcactccgat gaacttttca tttcgttctc
    14881 tcataacctc tcctttcatt cttgcggaga tacagccaat gtgctaaact aaacttaccc
    14941 cgttaggggg agagggcttc ttagccctct aattatcctc accactctat tgagtagtga
    15001 atcttaagct taaaccaaag aatcttgatt tcgacttcta gttctttgtg tttaggcttt
    15061 ttgtttagcc tagacttcat cagctgtacc tactttcatt tttgcttaat cccttaagct
    15121 tgattatagt atatctcaaa acgagatatt ttgtcaacta ttttttatct ctttttgaga
    15181 tttttttatt tacttttttg tttcttgatg ttatatttat agtagagaaa ggaaaaatat
    15241 tatgaatatt ctcggaaatt ctatcaaaga aattcgaaaa tccaaaaaaa tgacccaaaa
    15301 agagttagca aaactaactg gatttaaaca aaatacaatt tctaatcacg aaaatggtaa
    15361 tagacaactt gacgaagtag atattcgaaa atatgctaaa gcactgaaaa tagagccaca
    15421 acagcttttt gactattcct cttctcccac aaacccccaa gttgaactca tcccatctac
    15481 cctacaaaaa ataaactcta cttcttctca attagaacac agtagacaga taattgtttt
    15541 agatacagct gagactttat tggaacaaca gaaagaaatt aaaaacaacg aagatactat
    15601 tgccgaatta ttttcttaca actactacga ccacgcagct tcagctggta caggtcagta
    15661 tctaaatgat gtacaagtag aaaaaattga gttaccagtc gattatgacg cagactttgt
    15721 tatccctgtt tatggtgatt ccatggaacc gaagtatcac tctggggatt atgtatttgt
    15781 taagctatcc gtagagctta cagatggcga tataggcgtc tttgaatact atggtgacgc
    15841 ttatatcaaa cagttgctta taaacgctga aggggcgttt ttacacagtt taaatcaatg
    15901 cggtgattat ccagatatac cgatagatag agatagcgac tttaggatta ttggtgaagt
    15961 tatggggagt tatagggaga gataggcagg agcagaaatg gatagtaaag cattgaataa
    16021 acaaaattta agccgtagca agaaaattct gttgaatatc tctgataatc cgaaaaatcc
    16081 caaattttac aaattatcaa gacaagaact cgagcgcgct aaaattttta aaacagaaaa
    16141 cttaattaaa tctcaaaaat atcagagata caaacgagga actatcgtct ttattcattt
    16201 tggagtaaat atcggcaatg aattttccga ttcgcacttt gggattgtgc tgaataaaaa
    16261 agatcatccc aataacggaa agctaactat cttaccgcta acatcaaaaa actctaaaga
    16321 gagtctgtca attaacaaag agatttttac gagcataatg gatgatgccg aaaaaacagt
    16381 tcaaacagtt caaaatgtgc taaacctaac aactgaagta gaacggatac accactcgtt
    16441 accagttccc ccagcgtttt ttcagattaa aaaagaaaat aaatatcatg atatatggat
    16501 gaaatattac aataggcatg accctaaagg gattcatgtg cccgtagcaa acattaccgt
    16561 ccgaaaatgg atacaatcag acttagacaa aattaacttc ctcaaaaaaa gatatgcaaa
    16621 ttatgacaag gtgtcctacg ccaagctgga ctcaatcact tctgtcagta aactaaaaat
    16681 cgctaaacca attaacgatc ttgaccctgt cggaaaaata acattgtcta aagaaatcat
    16741 ggacaacatt gataaagctc tcgcaaggca gttattatct ggccagtggg ggaaacttga
    16801 caattaaata tcactatgtt agaattaagg tgtaatcttg gtagcctcgc taccactgaa
    16861 acattatttt ggagtgtcca actccactgt gagcgcctgt tttcgaataa gcgctctttt
    16921 ttgttttaaa aaaataaaaa agccccacgc tctcaaagtt tggcgactct gagcgtgagg
    16981 caagacagta taagaaacaa ccattaaaaa ggtcattttc ttgtacctat tttatcaaat
    17041 tgaaagatgg tatgcaatga aaattaaatc atataaaaag gaaaatggtg aaactgctta
    17101 taaatttctt ttgtatgccg gttatgttaa tggaaagaga aaatatatta ggcgagaagg
    17161 tttcaaaact aagcaggctg caagggaaac cttaattagt ttgcaagctg aacttgataa
    17221 acctaaatca agtatgacgt ttggtgtgtt aactaaacaa tggctaaacg aatatgaaaa
    17281 aactgtccag ggcagtacct acttaaaaac agaaagaaat attaataaac atattttgcc
    17341 aaaacttgat aaagtgaaga ttggagacat caacccacta cttatccagc ggcttactga
    17401 agaatggtgc aacgatttaa aatatggagg aaaaattctt gggcttgtta ggaatatctt
    17461 aaatctagct gttagatacg gatatatcaa taacaatcca gctttgccaa ttacacctcc
    17521 aaaaataaaa aggagaagaa aaatgaataa taatttttat acacttgatc aacttaaaca
    17581 attccttgaa ctagttgaaa aaactgacaa cattgaaaaa atagccttgt ttagattatt
    17641 agcatttact ggaatacgaa aaggggagct tctggcacta acttgggatg atttgaatgg
    17701 taatactcta tcaattaata aagctgtcac acgtactcaa gttggactag aaatagatgt
    17761 tacgaagaca aaatcgagcg atagattaat cagcttagat gatgaaactt tggaaatttt
    17821 acaagaactt catgaaactt ttcctacttc tactcttatg ttccaatctg aatcaggtgg
    17881 aattatgacg ccaagtttac cacgaaaatg gctattgcaa attatcaaag ggacagactt
    17941 accacaaatc acaattcatg gtttcaggca cactcatgca agcttacttt tcgaatcagg
    18001 tctatccttg aaacaggtgc aacataggtt agggcatgga gatttacaga caactatgaa
    18061 cgtatatact cacatcacgc aatcggcaat tgatgacatt ggaactaaat tcaatcaatt
    18121 tgttactaac aagcaactag attgacaact aattctcaac aaacgttaat ttaacaacat
    18181 ccaagtaact cccaccagct ccatcaatgc ttaccgtaag taatcataac ttactaaaac
    18241 cttgttacat caaggttttt tctttttgtc ttgttcatga gtttccgtta tccctatagc
    18301 cataccatca cgcttaccga tactccatca ataccactca aaaccttgtc atatcagatc
    18361 tttttgacca tttttttcat gaatatctaa aaaaaagaat caaaatagta ctaaattccc
    18421 catagcgcat gcgctatggg gaatcatagc tatatcttgt ttataattta tgatataata
    18481 cagcaaaaat agtttaggaa ataacatatg acaaaaaaac acttactaac acttcttctc
    18541 atctcttttt ttactagctt tttggtagct tgttcaacaa cgaaagataa agagcctcaa
    18601 ccgtctgatt cagaaatcat tactccccga ctacaccaag ccgctcatca agataaacgc
    18661 gctaactttg aaaaaattaa acttgcgact gttgattcct catttacagg agggacaagc
    18721 cttgaagaac ttatttcact ctttggagag cctagccaac atgatccaaa aacagcaggc
    18781 gaagtaacaa tcgacgctta tacttggcag tttgatcaag ttactctcac tgttaatctt
    18841 tatcaaaata gtagtattgt taaaaccatc tctaatttta cctttgcaag agagttaggc
    18901 ttatcgcaaa aggaatacca acaattacaa aaaggaatgt cttatgaaga cgttaaaaag
    18961 atcttaacag aacctgataa ttatagccaa gcgtcatcta gtgatcatca aactttgcaa
    19021 gcgatttggg ttagtggctt aaagacagat acaagcggag ctaatatttc tctcgttttt
    19081 gaaaataatc agttaacaga aatgtctcag gtaggacttg aagaataaaa aatgagtaat
    19141 atattttgct aaaaagatt
//
LOCUS       DATWVB010000032        18935 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.032, whole genome shotgun sequence.
ACCESSION   DATWVB010000032 DATWVB010000000
VERSION     DATWVB010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18935
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.032"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            178..2010
                     /gene="lepA"
                     /locus_tag="VCX65_001303"
     CDS             178..2010
                     /gene="lepA"
                     /locus_tag="VCX65_001303"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEP5053763.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK"
     gene            2197..3498
                     /locus_tag="VCX65_001304"
     CDS             2197..3498
                     /locus_tag="VCX65_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP5053764.1"
                     /translation="MNKTKQNKTKQNKTKQNKTKHSLLCRYGLTSAAALLLTFGGASA
                     VKADEQEEKAKVRTELIQELAQGLGGIEKKNFPTLGDEDLDHTYMTKLLTYLQEREQA
                     ENSWRKRLLKGIQDHALDGQDGRNGERGEQGPTGPTGPAGPRGLQGLQGERGEQGPTG
                     LAGKAGEAGAKGETGPAGPQGPRGEQGPQGLPGKDGEAGAQGPAGPMGPAGERGEKGE
                     PGTQGAKGDRGETGPVGPRGERGEAGPAGKDGERGPVGPAGKDGQNGQDGLPGKDGKD
                     GQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQDGKDGLPGKDGKDGLPGKDGQPGKPA
                     PKTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQNPSNRGLNKPQTQGGNQLAKTPAA
                     HDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVAKRQENN"
     gene            3684..4121
                     /gene="msrB"
                     /locus_tag="VCX65_001305"
     CDS             3684..4121
                     /gene="msrB"
                     /locus_tag="VCX65_001305"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEP5053765.1"
                     /translation="METSDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET"
     gene            4251..5270
                     /locus_tag="VCX65_001306"
     CDS             4251..5270
                     /locus_tag="VCX65_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEP5053766.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLL
                     ALFYHHRDKAKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNDGFATFAGTAVNDTSSVTATATAWDALHHSNTLDDATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSFGVS
                     ADVFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            5477..5902
                     /locus_tag="VCX65_001307"
     CDS             5477..5902
                     /locus_tag="VCX65_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP5053767.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDNFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDDIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            5921..6412
                     /locus_tag="VCX65_001308"
     CDS             5921..6412
                     /locus_tag="VCX65_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEP5053768.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            6429..7238
                     /locus_tag="VCX65_001309"
     CDS             6429..7238
                     /locus_tag="VCX65_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEP5053769.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            7235..8062
                     /locus_tag="VCX65_001310"
     CDS             7235..8062
                     /locus_tag="VCX65_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEP5053770.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            8198..9847
                     /locus_tag="VCX65_001311"
     CDS             8198..9847
                     /locus_tag="VCX65_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP5053771.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            9851..10639
                     /locus_tag="VCX65_001312"
     CDS             9851..10639
                     /locus_tag="VCX65_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5053772.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            10633..11679
                     /locus_tag="VCX65_001313"
     CDS             10633..11679
                     /locus_tag="VCX65_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP5053773.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNIAMYIFSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDV
                     YESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAK
                     QFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKIL
                     NTYNRLHEALERGK"
     gene            11792..13189
                     /locus_tag="VCX65_001314"
     CDS             11792..13189
                     /locus_tag="VCX65_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HEP5053774.1"
                     /translation="MAYQTIYPYTNEVLHTFDNMTDQDLADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEF
                     LMSTPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGVKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNSNTKV"
     gene            13291..15087
                     /gene="uvrC"
                     /locus_tag="VCX65_001315"
     CDS             13291..15087
                     /gene="uvrC"
                     /locus_tag="VCX65_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEP5053775.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFL
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNL
                     FPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLKIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            15272..15874
                     /locus_tag="VCX65_001316"
     CDS             15272..15874
                     /locus_tag="VCX65_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEP5053776.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            15999..17408
                     /gene="pepV"
                     /locus_tag="VCX65_001317"
     CDS             15999..17408
                     /gene="pepV"
                     /locus_tag="VCX65_001317"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEP5053777.1"
                     /translation="MTTIDFKAEVDKRKEAMLADLVDLLRINSERDDRSADDQHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNKGAFVLHRFQGGLREN
                     MVPESATAVITAPHDLDVLEAALEQFLSEYGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGINGATLLAKFLNQFTFEGAAKDYLHVAGEVLHEDFAAEKLGLAYTDDRMGALSMNA
                     GVFNFDSQSADNTIALNFRYPKGTDAATLKSGLEKLPGLTKVSLSEHEHTPHYVPMDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(17476..18852)
                     /gene="mnmE"
                     /locus_tag="VCX65_001318"
     CDS             complement(17476..18852)
                     /gene="mnmE"
                     /locus_tag="VCX65_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEP5053778.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQGSNRI
                     ILLNKTDLEQKIELEQLPADLISISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
BASE COUNT         5803 a         3491 c         4063 g         5578 t
ORIGIN      
        1 agaggctaag cagatgattg atttaaaaag gaatcttttc aaaattgatg tccgggcaca
       61 aaaggatgaa gagaaagttt tcatgcgtac ggcgtggata atccgtaaga aaagataggc
      121 aaaggcctac cttttttgtt ataatagaag gaaagactaa atgtatagga aaatagaatg
      181 aacagtcaag atttaaaaaa acgtcaggag aagattcgta atttctccat tattgcacat
      241 attgaccatg gcaaatctac tctcgctgac cgtattttgg aaaagacaga gacggtttcg
      301 tctcgtgaaa tgcaggctca gttattggac tccatggatt tggagcgtga gcgtgggatt
      361 accatcaagt taaacgccat tgagcttaat tacacggcta aagatgggga aacctacatt
      421 ttccacctta ttgatacccc agggcatgtg gactttactt atgaagtatc gcgttcgttg
      481 gcagcctgtg agggagcgat tctagttgtg gatgcagcgc agggcattga agcacagacc
      541 cttgccaatg tttacctagc ccttgataat gatttggaaa ttttaccggt tatcaataaa
      601 attgacttgc ctgctgctga ccctgagaga gtccgccatg aagtagaaga tgtcattgga
      661 cttgatgctt ctgaggctgt tctggcgtca gccaaggctg gtattgggat cgaagagatt
      721 cttgagcaaa ttgttgagaa ggttcctgct cctacgggtg atgtggatgc gcctttacag
      781 gccttgattt ttgactctgt gtatgatgct taccgagggg taattttgca ggttcggatt
      841 gtgaacggta ttgtcaagcc tggcgataaa atccagatga tgtcgaatgg aaaaaccttt
      901 gatgttacag aagttgggat tttcactcct aaggcagttg gacgagattt ccttgcgacg
      961 ggagatgttg gttatgttgc ggcctctatc aaaacggtag cagatacccg tgtgggcgat
     1021 acggtgactt tagctaataa ccctgctaag gaagccttgc atggctacaa gcagatgaac
     1081 ccgatggtct ttgcagggat ttatccgatt gaatcaaata aatacaatga cttgcgtgaa
     1141 gcgcttgaaa aattacaact gaacgatgcc agtttacagt ttgaacccga aacgtcacaa
     1201 gcgcttggct ttggttttcg atgcggtttt ttaggcttgc ttcacatgga tgtgattcaa
     1261 gaacgtttgg aacgtgaatt taacattgat ttgatcatga cagcaccgtc cgtggtgtat
     1321 cacgttcaca caacagatga ggacatgatt gaagtgtcta acccttcaga atttccagat
     1381 ccaacacggg tggcttttat tgaagagcct tatgttaaag cgcaaatcat ggtgccacaa
     1441 gagttcgtag gggctgttat ggaattatcg cagcgcaagc gtggtgattt tgtgaccatg
     1501 gattacattg atgataaccg tgtcaatgtg atctaccaaa tcccgctggc tgaaattgtc
     1561 tttgatttct ttgataaatt gaaatcctca acgcgaggct atgcgagttt tgattatgac
     1621 atgtcagaat accgcaggtc acaattggtg aaaatggaca ttcttttgaa cggtgataag
     1681 gtcgatgcgc tcagctttat tgttcataaa gaatttgctt atgaacgcgg gaaaattatt
     1741 gttgagaaat tgaaaaaaat cattccacgt caacagtttg aagtgcctat tcaagccgct
     1801 attggtcaaa aaattgttgc gcgttcagac atcaaggccc ttcgtaaaaa cgttttagcg
     1861 aagtgttatg gtggtgacgt gtctcgtaaa cgtaaattgc tcgaaaaaca aaaggctggt
     1921 aaaaaacgga tgaaggctat tggttctgtt gaagtccctc aagaagcctt cttgagtgtt
     1981 ctttcaatgg atgacgatgc caagaaataa ccaagcctaa tcgcttagtc ttcagaggag
     2041 aactcttgtg ggtctacatg accaaaaaat ggttatctta tacaaaaaga actttacaat
     2101 catttgcaca taatgttata ataatattat agtgttatct cattattagg tgcgcctgca
     2161 tttaatctta ttaaacagaa agaggaaaca aaaactgtga acaaaacaaa acaaaacaaa
     2221 acaaaacaaa acaaaacaaa acaaaacaaa acaaaacata gccttctttg tcgctatggc
     2281 ttaacctcag cggctgctct tttgctgacc tttggaggtg caagtgcagt taaggcggat
     2341 gaacaagaag agaaagctaa agttagaact gaattaattc aagagttagc tcagggacta
     2401 gggggtattg agaaaaaaaa ttttccaact ctaggtgatg aagatttaga tcatacttat
     2461 atgacaaagc tattaacata cctacaggaa cgagaacaag ctgagaatag ttggcgaaaa
     2521 agactactaa agggtataca agatcatgcc cttgatggac aagacggtcg aaacggtgaa
     2581 agaggggaac aaggaccaac aggtccaacc ggacctgctg gtccacgagg tctacaaggt
     2641 ctacaaggtg aaagagggga acaaggacca acaggtctcg ctggtaaagc cggtgaagct
     2701 ggagccaaag gcgaaaccgg ccccgctggt ccacagggtc cacgtggtga acaaggcccg
     2761 caaggtcttc caggtaaaga tggtgaagct ggtgctcaag gcccagcagg tccaatgggt
     2821 cctgctggtg agcgaggtga aaaaggagaa cctggtaccc aaggcgctaa aggtgatcgc
     2881 ggtgaaaccg gtccagtagg tccacgtggt gagcgaggcg aagccggtcc cgctggaaaa
     2941 gatggtgaac gtggtccagt aggtccagct ggtaaggacg gccaaaacgg ccaagatggt
     3001 cttccaggta aagacggtaa ggacggccaa aacggtaaag atggtcttcc aggtaaagac
     3061 ggtaaggacg gccaaaacgg taaagatggt cttccaggta aagacggtaa ggacggtcaa
     3121 gatggtaaag acggcctccc aggtaaagac ggtaaagatg gcctcccagg taaggacggt
     3181 caaccaggta aaccggctcc taaaacacca gaggtccctc aaaaaccaga taccgcacca
     3241 catacaccaa aaacccctca gatccctggc caatcaaaag acgtgacacc tgcccctcaa
     3301 aacccttcta atagaggtct aaacaaacca caaacacaag gtggtaatca gctcgcaaaa
     3361 acaccagcag ctcacgacac acacagacaa ttgccagcaa caggcgaaac aaccaatcca
     3421 ttctttacag cagctgctgt agctatcatg acgacagctg gagttgtagc tgttgcaaaa
     3481 cgtcaagaaa acaactaatc ctctttttgc tacctaactg atggaaagta aaactcagag
     3541 agaacctcaa ggttctctct tttttgaatc aagatagtag ctctaggtat aacgtcttgt
     3601 ctgaggtgct gtgaacaaat cagttaccac tcacctcttt ttttggtaaa atgtaagcac
     3661 taagacatca aaaggagttt tccatggaaa catcagatga gttaaaacaa cgcattggtg
     3721 atctttctta cgaggtcacc cagcatgcag caacagaatc tccctttaca ggcgaatatg
     3781 ataatttttt tgagaagggt atctatgtcg atattgttag tggtgaggtc ttattttcat
     3841 cactggataa atttaattct ggctgtggtt ggcctgcctt ttcaaaaccc attgaaaatc
     3901 gtatggtcac aaaccacgat gactcttctt atgggatgag acgagttgag gttaaaagcc
     3961 gtgaagcagg atcgcatttg gggcatgtct ttagtgacgg ccccaaagaa gctggaggct
     4021 tgcgttactg tatcaattca gcagctctta aattcattcc ttatgagcag atggaaaaag
     4081 aaggctatgc ccagtggctc acattgtttg atgagacata accgggtttc aaaatgactg
     4141 aaaaagaagc gtcagtgatt cccacaagca ctggattggt gaggcgtacg ggtcaatttt
     4201 acaagccttt gtaaaaggtc tataataggg aatgaaaaaa ggaggttagt atgtcaactc
     4261 acttaagaaa acttccaggg ctgttacttt gcttgttgtt agctcttcca gcctggtatt
     4321 tagggcgctt atttcccatt attggagcac ctgtttttgc tattctttta ggaatgttgt
     4381 tagccttgtt ttatcaccat cgtgacaagg ctaaagaggg aattagtttt acatccaagt
     4441 atattttaca aacagcagtt gttttgcttg gttttggatt aaacctaacc caagttatgg
     4501 cagtgggcat gcagtcttta ccgattatca tttcaactat tgcgacagct cttttggtag
     4561 cttatggctc acagaaatgg ctgcgcttag atgtcaatac agccaccttg gtgggtgtag
     4621 ggtcttccat ttgtgggggg tctgctattg cagcgacggc tcctgtcatt aaggcaaagg
     4681 atgatgaggt tgctaaggca atttcagtca tttttctctt taatatgtta gcagctttgc
     4741 tatttccaag tttaggacaa ttactgggct tatctaatga tggttttgct acttttgctg
     4801 ggacagctgt taacgacacc tcttccgtga ctgcaacggc cacggcctgg gatgcccttc
     4861 accattccaa tacactagat gacgcaacca ttgtcaaatt gactcgcacc ttggctattc
     4921 ttccaattac tttaggttta tccctttacc gagcgaaaaa agagcacgac atcgttacag
     4981 aagaaaactt tagccttagg aagtcattcc ctcgtttcat cctcttcttt ttattagctt
     5041 ccctcatcac gacattgatg accagctttg gtgtttctgc cgatgttttc cattccctaa
     5101 aaaccttatc aaaattcttt atcgtgatgg ctatggcggc tatcggttta aatacaaacc
     5161 tggttaaatt aatcaagacg ggcggtcagg ctatcctttt aggagctatt tgctgggtag
     5221 ctatcaccct tgtcagttta gccatgcaat taagtttggg catttggtaa tcagacacga
     5281 gaaatcagtt tgactgattt ctttttttgt atcttatttg tgtagaattg tctacatttt
     5341 aaagagaata gtgcatttta aaaacgtttt catttgataa aataaaccta tcgttaaacc
     5401 agttcagtaa agacaactgg ttgagataag caattaccgt ttattcagcg gtttttgtta
     5461 atagaggagg ataggaatga aacgaaaatt tctcattggg agtcacggca gactagccag
     5521 tggtttgcaa agctctattg acattttagc aggtatggga caggcacttg aaaccattga
     5581 tgcttatgtt gatgatagtg actacactag ccagattgat aactttatcg ctggggtagc
     5641 agcagatgag cagggcctta tttttacaga tttgttaggc ggcagtgtga atcagaaaat
     5701 ggtaaccgct gtaatgaaca gtggcaaaga caatatcttt ttaatcacaa acagtaactt
     5761 agccacttta ttgtcgttgg tgtttttaaa accaggcgaa gcgcttacta aagatgatat
     5821 tgtaaccgtt atcaatgaat cgcaagttca gttagtggat ttggtccctg agacaaattc
     5881 agaagatgac ttttttgatt aatatctagg aggaagacaa atgattactc aaattcgtgt
     5941 tgacgaccgt ttgattcacg ggcaagtggc agttgtatgg accaaagagt taaatgcgcc
     6001 acttttagta gtggctaatg atgaagctgc aaagaatgaa atcacacaaa tgacgcttaa
     6061 aatggctgtg ccaaacggca tgaaactgct tattcgttca gttgaagact cgattaagct
     6121 ctttaatgat ccacgcgcca aagacaagcg tatttttgtg attgtcaatt ctgttaaaga
     6181 tgcttgtgcc attgctaaag aagttccaga cttagaagct gttaatgtgg ctaacgtggg
     6241 gcgttttgac aaatcagacc cagcaagcaa agtcaaagtg acaccaagtc ttttacttaa
     6301 cccagaagaa atggcagccg caaaggaatt agtcagttta ccagaacttg atgtctttaa
     6361 ccaagtctta ccatcaaata ccaaggtcca tttgagccaa ttagtcaact aaagagaggt
     6421 aaaaaagtat gttagtacca gcaacaatgg cagctttagc tgtattgatt tgttttgggg
     6481 gaaattattt aaccggtcaa agcatgatgg aaagacccct agtagttgga ctggtcacag
     6541 gtcttctttt aggagatatg aaggtcggta tcttaatggg ggcctctcta gaagctcttt
     6601 tcctaggaaa tgtgaatatt gggggtgtta ttgcagctga gcctgtaaca gcgactgcca
     6661 tggcaacaac ctttaccatt atttcacata ttgaccaaaa agcagccatg accctagctg
     6721 ttccaattgg aatgttggca gcctttgtgg ttatgttttt gaaaaacgtc ttcatgaata
     6781 tctttgctcc aatggttgat aaagctgcag cagctaacca tcaaggtaaa ctagtgatgc
     6841 tccactatgg cacttggatt atctattact tgatcattgc ctctatttct ttcattggta
     6901 ttttagtagg tagtggacct gttaatgcct ttgtggaaca cattcctcaa aatctcatga
     6961 atggcttgag tgctgcggga ggccttcttc cagctgtcgg ttttgccatg ctgatgaaat
     7021 tattgtggac caacaaatta gctgtttttt acctattggg ctttgtctta acagcttatt
     7081 tgaaattacc agcggttgca gttgctgccc taggagcagt tatttgcgtc attagttccc
     7141 aacgtgatct agaattagac gcaattacta gaggtgcaat tagtaaacaa acaacctttg
     7201 actctaaaga atcagaagag gaggacttct tcgcatgaca tcacaagata atttgactaa
     7261 agaagaccgt aaaatgcttc gctcagtctt ttggcgctca tggacgatga atgctagtcg
     7321 tactggggca acacaatacc acgcagtagg ggttatttac actttactac cagtcatcaa
     7381 tcgtttttat aagactgata aggataaagc agaggcactg gtccgtcata caacatggtt
     7441 caatgccacc atgcacatca ataactttat catgggtctt gtggcatcga tggaaaagaa
     7501 aaacagtgaa gatcctgatt ttgatgctag tgctatcacc gctgttaagg cttcgttgat
     7561 gggacctata tctggagttg gagattcctt cttctgggga attttaaggg ttattgcggc
     7621 aggtatcggg atttccttgg caagtgcagg ctcagccatg ggagctgttg tcttcttact
     7681 cttgtacaat attcctgctt ttattattca ctactatagc ctttatggtg gttattctgt
     7741 aggtgcagga tttatcaaaa aactttacga atctggtggt ataaaaatcg tcactaaaac
     7801 ctcaagcatg cttgggttaa tgatggtagg ctcaatgacg gcttcaaatg taaaatttaa
     7861 aacgattctt acagttgctg cgaaaggtgc caaagaagca gcttctattc aagattacct
     7921 tgaccaattg tttattggta ttgtaccatt aatggtaaca ctagcagctt tttggcttct
     7981 acgaaagaaa gtgaatatca actggattat gtttggtatc atgttccttg gcattatcct
     8041 tggactttta ggtatttgct aataatctcc tagcaataaa ggtaagtaag acaagttttc
     8101 ttgttttgct tacctttttc cttttaagat gatgagactt gttttgatga aaaacgtagt
     8161 agcattaaga aatttgttat aatgaaagga gcttaagatg cgaggtgaac aggtggaaga
     8221 acattttaaa aaacaattac aagatgatat ttctagacat ttttcgtacc aatcgttaat
     8281 gttatcattg ttgctaattg gtctttttat tattttttca ttagcgccac aacaattagg
     8341 cctctatcgt gatatcaatg ccactgcaac ccgttatcac cgtttgatta gcaaacaaga
     8401 agccttgctt gatgacttag ggaaaaatag cttactacct tttttaaata aaaacctcag
     8461 cactgctgat ttaagcaagc actattttca tttgcgccat agcagccaaa cgtcaccaga
     8521 acttttacta ttttcaccta gtcaagacct tttatttgct agtaacccac atttaggaaa
     8581 tgtttttagt aaatctgttt atattcaaga agtcttgaga gcagctcatc ctccaaaaac
     8641 cttgtttaaa gttgctatgg atagtgaaga tggtcactac ttgatgatca ttaagccaat
     8701 gattgatcaa aaccaactaa agggatatgc ttttttagtg atgagtggca aagattttct
     8761 tcatcctaca aaaacactga cgtcagagtt ggtcattgct gataagctgg acaatacgtt
     8821 tacgttttcc aatcgtgagt ttatagcatc tagtctagat aagatcaaca gtcagtattt
     8881 acaccattat tttgtttttc aagataatcg agcctttatc acaagaaagg ttgccttaca
     8941 aggaggtctt tggctttaca tgtataggcc cttgattcca atggtatcgg tgatgttatt
     9001 ttcacttatt tcatcagctg ttatctttgt gatcttgcaa cgtaaatcaa gtggtttagc
     9061 taaccgaatt gcagctaaaa attcaagagc aatcaatcaa atggttagag atatgagtgc
     9121 gatctctcgg caagaaaaaa gacgtattga ccttgagagt caagatgaat ttcaatattt
     9181 atctgatcaa atcaatcaaa tggtagagcg attgcaacag ttacatgata aaacgttaga
     9241 tttggaaact caaaaattat tatttgaaaa acggatgtta gaagctcaat tcaatccgca
     9301 tttcctctac aatacgctag aaaccatttt gattacgagc cattatgatt ctgccctaac
     9361 agaaaaaatt gttatccaat tgacaaaatt gttgcggtat agtctcacgg attctagcaa
     9421 acctgtcttg ctcaaagatg atttaagtgt catcgagtct tatttagtga ttaatcaggt
     9481 gcggtttgaa gaattgcaat atagcattaa cctatcccca gaccttgata gtcttgcagt
     9541 gcctaaattg ttcttgttac ctttgataga aaatgccatc aaatatggct tgaaagaacg
     9601 acacgatgtc aagattaaca ttgcttgtta ttatcaagat gaccatatta ttttttctgt
     9661 gcgagataat ggttcgggaa ttgatgctca tcaccaaaaa gtgattcgag agcaattgga
     9721 agctggagag tcacaccatg ggttaattaa ctcttatcgt cgacttaagt atcatttttc
     9781 agaagtatcc ttggtttttg atcaaggtga taaacagttt aatgttagct accatgttaa
     9841 ggagtagtct atgtacaaat tagtcattat tgaagatgaa catattatta ggaaatggtt
     9901 gcgatacgct attgattata aagctttaga tattttggtc attggcgagg ctaaagatgg
     9961 caaagaagga gctgttttaa tcaaagagag tcaaccagat atcgttttaa ctgatattaa
    10021 catgcccatc atgacagctt ttgacatgtt tgaagcaaca aaagatcaaa cttacgccaa
    10081 aattatttta tctggctatg ccgattttcc aaatgcaaga tctgctatac actacggtgt
    10141 acttgaattt ttaacaaaac cgattgaaaa agcagctctt tgggaatgtc ttcaaaccat
    10201 tattgctaaa atagaaaagc aaaaggggtc taatcaaaaa acagatgctt gcgtctatat
    10261 tcccttaccc cagatgactg atcagattcc tgaagtagtc aaagatattt tggagtgggt
    10321 acatgctcat tttcaagaca agatcagcac gagccgccta gctcatgact tagggtatag
    10381 tgagagttat atctatcaaa atatcaaaaa gcatcttcag atgcctttaa gtgattacat
    10441 taatcaatat cggattaatc aggcaattca attgatgcaa caagaaccag atttaatggt
    10501 atatgaaata gcacaagctg taggtattta tgactatcgc tattttgata gggtttttaa
    10561 aaagtatcta ggacaaactg taaaggcttt taaagaagag cattttatga aggataccga
    10621 taggagtaag ccatgttaaa actcaaacgc aaatggctat taagcttttt gttagtaata
    10681 attattctag caatcgttaa cattgcaatg tatatattct catcgtcaaa aaaagatagt
    10741 gctaaagaat tagttatctt gactcctaat agccaaacta ttttaacagg gactattcca
    10801 gcctttgagg aaaagtatgg ggttaaagta agattaatcc aaggtgggac gggccaactt
    10861 attgatcaat taggtcgaaa agataagcca ttaaacgctg atattttctt tggtggcaat
    10921 tacactcaat ttgaaagcca taaagattta tttgaatcct atgtttctcc gcaggtttct
    10981 actgtcattt cagattacca attgcctagt catcgtgcaa ccccatatac gatcaatggc
    11041 agtgtactga ttgttaataa cgaattagca agaggacttc atattaccag ttatgaggat
    11101 ttgctacaac cagctttaaa aggcaaaatt gcttttgctg acccaaatag ctcatctagc
    11161 gctttttcac aattaacaaa catcttactg gctaaaggag gctatacgag ctcagaagct
    11221 tgggagtatg tgaaacgttt attactgtct atgaattcta tcagagcaac aagttcttca
    11281 gatgtttacg aatctgttgc agaaggtaaa atgattgttg gtttgaccta tgaagaccct
    11341 tgcatcaatc tgcaaaaaag cggtgcaaac gtttcgattg tttatccgga tgaggggaca
    11401 gtatttgttc cgtcatcagt cgctattatc aaaaaagcaa aggcaatgaa agaagctaag
    11461 caatttatta attttatttt atcatcagat gtacaaaatg cctttgggca gtcaactagt
    11521 aatagaccta tccgacgaga tgctcaaacg agtcatgaaa tgaaaccatt agatgaaatt
    11581 attactttaa aagaagatta cggatatgtt actagacata agaaaaaaat attgaatacc
    11641 tataatcgac tacatgaagc attagaaaga ggaaagtaga ctctaggctt gttgttgcta
    11701 tactagtagt gttacaaaat agcgtagtca ttttttgaaa tcgatttcat aatctggtag
    11761 actaagatta tcacgaaaag gagataatat aatggcttat caaactattt acccttatac
    11821 aaatgaagtc cttcatacat ttgataatat gaccgatcaa gatttggcag atgtccttga
    11881 aagagctcac cttctctata aaaaatggcg caaggaagat catttagaag aacgtaaagc
    11941 ccagcttcat caagtggcta atattcttcg ccgtgaccgc gataaatatg ctgaaatcat
    12001 gaccaaagac atgggaaaac tgttcacaga agcccaaggt gaagtagatc tttgtgccga
    12061 tattgctgat tactacgctg ataaggcaga tgaatttttg atgtctacgc cactagaaac
    12121 agattcaggt caagcttact atttgaaaca atcaactggt gttattctag ctgttgaacc
    12181 ttggaatttc ccttactatc aaatcatgcg ggtctttgcg ccaaacttta ttgttggaaa
    12241 cccaatggtt ttaaaacacg cttctatttg cccacgatct gcccaatcct ttgaagaatt
    12301 agttcttgaa gctggtgctg aagcaggtag tattaccaat ttgtttattt cttatgacca
    12361 agtatcacaa gtgattgctg ataaacgtgt ggttggtgtc tgcttgacag gttccgaacg
    12421 tggaggagct agcattgcag aagaagctgg taaaaacttg aaaaaaacaa cccttgaatt
    12481 gggtggcgat gatgccttta ttatccttga tgacgcggat tgggatcaat tagagaaggt
    12541 gctttacttc tctcgtctct acaatgcagg tcaagtatgt acctcatcga aacgttttat
    12601 cgtgcttgac aaagactatg accgtttcaa agagttatta acaaaagtct tcaaaacagc
    12661 taaatggggt gatccaatgg atcccgaaac gacgttggcg ccattatcat cagctcaagc
    12721 taaagcagat gttcttgacc aaattaagtt ggccttggat catggtgcgg agttggttta
    12781 tggtggtgaa gcgattgatc atccaggtca ttttgtcatg ccaaccatta ttgctggcct
    12841 cacaaaagac aaccctattt actatcaaga aatctttggc ccagtcggtg aaatctacaa
    12901 agtgtcttct gaagaagaag cgattgaagt ggcgaatgat tctaactatg gccttggagg
    12961 tactatcttt agtagcaatc aagaacatgc gaaagccgta gctgctaaaa ttgaaactgg
    13021 tatgtctttt atcaactcag gctggacaag tcttccggaa ctcccatttg gtggggttaa
    13081 acattcaggc tatggccgtg aattgagtga gcttggcttt acatcttttg tgaatgaaca
    13141 ccttatctat attccgaata aaacgaataa tagcaatact aaagtttgat ctagattgtt
    13201 aaagaagagt gtaacgcctt aataaacaat caaggcgtta cactcttctt ttttaaagtc
    13261 aaaattttaa aaatttgata aactaataac atgaacgaac tgattaaaca taaactagaa
    13321 ctcttaccag acagccctgg ctgttactta cataaagata aagaaggaac tattatctat
    13381 gtcggtaagg ctaagaattt gaaaaaacgc gtccggtcct attttcgtgg gagccatgat
    13441 accaaaacag agttactagt atctgagatt gtagatttcg aatatattgt aacagagtca
    13501 gataccgaag cgcttttgtt ggaaattaac ttgattcaaa aaaatatgcc taagtacaac
    13561 atcaagttaa aagatgataa atcttatccc tttctcaaaa tcacaaatga gtcttttcct
    13621 cggttagtga ttacaagata tattaagaaa aatgatggat tgtactttgg gccctaccca
    13681 gattcttaca ctgctaatga agttaaaaag ttattagata ggatttttcc atttaaaaag
    13741 tgtaaaaatc ctatcaataa ggtctgtttt tattaccatt taggccagtg ctgtgctcat
    13801 accatttgtc atacagacaa ggcctattgg gatcgtttaa ttgatgatgt taagcacttt
    13861 ttaaatggta aagatgacaa aattattgaa gatcttcgtt ctaagatgtt agcagcttct
    13921 gaagaaatgg catttgaacg tgccgctgaa tatcgagatt tgatttcagg tattgccacc
    13981 atgcgcacca agcagcgggt gatgagcaag gatttgcaag atagagatat ctttggctat
    14041 tatgttgata agggatggat gtgtgtccaa gttttctttg tgcgtcaagg gaaattaatt
    14101 cagcgtgatg ttaacctttt tccctattat aacgatgcag aagaagattt cttaacttat
    14161 atggggcaat tttaccaaga taaacagcat ttcatcccta aagaagtctt tattccagaa
    14221 gctattgatg aagaactggt agccgctatt gtgccaacca aaatcatcaa acccaaacgc
    14281 ggtgaaaaaa aacaactggt agctttggct actaagaatg ctcgtgttag tctgcaacaa
    14341 aaatttgatt tattagaaaa agatatcaaa aaaacgagtg gtgctatcga aaatttaggt
    14401 cagttactta agattgacaa gcctgtgcgc attgaagcct ttgataattc taacattcaa
    14461 gggacaagtc cagttgcggc tatggttgtt tttgttgatg gcaaacctag taagaaagat
    14521 tatcgtaaat ttaagattaa aacagtggtg ggaccagatg attatgccag tatgagagaa
    14581 gtgctttttc gaaggtacag tcgggtgaaa aaggagggac tgcaagctcc taacttgatt
    14641 attgttgatg gaggcgttgg acaagtcaat gtggccaaag atgtgataga aaaacaactt
    14701 ggactcacta ttcctgttgc gggacttcaa aaaaacgata agcaccagac ccatgatttg
    14761 ctttttggaa acccacttga agttgtaccg ttgccgcgcc gttctgaaga gtttttctta
    14821 ctgcatcgga ttcaagacga agtgcatcgc tttgcagtta catttcatag acaagtgcga
    14881 cgtaaaaatt ctttttcatc aacattagat catatttcag ggcttggccc aaagcgaaaa
    14941 cagttattac taagacactt taaaaccata acagcgattg catcagctac ctctgaggag
    15001 attcaagctt taggtatacc taaaacagta gttgaagcaa tacagcaaca gataacagac
    15061 aataaaaatg atagatcgtc tccttaaata agtgttatgt tttcagtact gatgaggtaa
    15121 aaaggcgcta cttgttacgc acgacatttc agttcgttat tttgaaactt tcagaaagtt
    15181 gcgaagtgta gtgagtttat gattttaaaa actattttat ggtaaaataa aatggtatta
    15241 aaaaaaacag atttagatag gaagttttga aatgaaattt ctagagttaa acaaaaaacg
    15301 ccatgccatt aagaccttta atgaccagcc agttgactac gaggatttgc gaacagccat
    15361 tgagattgca accttagcac ctagtgccaa taacattcaa ccttggaaat ttgtagtcgt
    15421 tcaagagaaa aaagctgagt tagcaaaagg gttacctcta gcaaataaag tgcaggttga
    15481 acaggctcaa tatgtagtgg cgctattttc agacactgat ttagctttac gttctcgtaa
    15541 aattgcccgt atcggtgtca aatcgttacc agacgactta attggttatt atatggagac
    15601 tttgccacca cgttttgctg cctttaatga ggttcaaacc ggtgagtact tagctattaa
    15661 tgcaggcatt gtggctatga acttggtgtt atccttgacg gatcaaaaga ttgcttccaa
    15721 tattatcctt ggttttgata agtcaacgac caatgaaatt ttagacatcg atccgcgttt
    15781 tcgtccagaa ttattgatta ctgttggcta tagtgacgag aaaccagaac caagttatcg
    15841 tttgcctgtt gatgaagtca tcgaaagaag atagagtcag gacaattagt taaatgtaat
    15901 gtccagatgc gctacggagc gaccgctatt gttagactga tactattttg gcttatttta
    15961 agttaaacat tatccctaaa acgaataagg agagtataat gacaaccatt gattttaaag
    16021 cagaagttga caaacgtaaa gaagctatgc tagcagattt agttgaccta ttacgcatta
    16081 attcagaacg cgatgacaga tcggccgatg atcagcatcc ctttgggcca ggtccagtta
    16141 aggctttgga gcatttcctc gcaatggctg agcgtgatgg ctacaaaacg cgtaatattg
    16201 ataactatgc aggtgacttt gaatttggtc aaggtgatga agtactagga atctttggcc
    16261 accttgatgt tgtgccagct ggtagcggtt gggatacaga cccttatgag ccagtgatta
    16321 aagacgatcg catctatgcg cgtgggtctt cggatgataa gggaccaacc atggcgtgct
    16381 actacgctct gaaaatcatt aaagaattgg gtcttcctgt gtctaaaaaa gttcgtttca
    16441 ttgttggtac cgatgaagaa tctggctggg gggatatgga ttattacttt gctcataatg
    16501 gcttgaaaaa tccagatttt ggtttctcac cagatgctga atttccaatt atcaatggtg
    16561 agaaaggaaa tatcaccgaa tacctccatt tcgctggtga caacaagggc gcttttgtgc
    16621 ttcatcgctt ccaaggtggg ttgcgtgaaa acatggtacc agaatctgcc acagctgtca
    16681 ttacggcacc gcatgacctt gatgtgctag aagcagcctt ggagcaattt ttatcagaat
    16741 atggtgttaa aggctctatg aaggctactg atggtaaaat tgaagtaact attattggga
    16801 agtctgctca cgggtcaact ccagaagctg gaatcaatgg tgccaccttg ctggctaaat
    16861 tcctgaatca atttaccttt gaaggggctg ctaaagatta tttacatgtg gcaggtgaag
    16921 tgcttcatga agactttgcg gcagaaaaac taggccttgc ttataccgac gaccgtatgg
    16981 gagccttgag catgaatgca ggtgtcttta actttgatag tcaatcagct gacaatacca
    17041 tcgccttgaa tttccgttat ccaaaaggga ctgatgcggc aaccttaaaa tcaggattgg
    17101 aaaaattacc aggtttaact aaggtaagcc tttctgagca tgaacataca cctcattatg
    17161 tgccaatgga tgatgaattg gtagcaacct tgcttgctgt ttacgaaaaa caaacaggtc
    17221 ttaaaggcta cgaacaagtt atcggcggag gaacctttgg tcgtttgcta gaacgtggtg
    17281 tggcctttgg agcaatgttc ccaggtgatg aaaacactat gcaccaagct aatgaatata
    17341 tgcctttaga aaatatttat cgctcagcag ctatttatgc tgaagcaatc tacgaattaa
    17401 ttaaataaga tgtttatgac agcaaaaaga gctggaacag tgttccagct cttttgtgat
    17461 gattagagac tgttgttatt taccaagaca gaattgacta aagagttggg taatgagctc
    17521 atcaggagca gcatcccctg tgatttctcc gagaatttcc caagttctgg ttaaatcaac
    17581 ctgtagtaaa tcaactggca tgccaagcgc caagccgtca ttgacagctt ctaaactctg
    17641 gactgccttt tcaatcaaag aaatgtggcg ggcatttgac aggtaagtgg catcttgttc
    17701 tactagtcca gcattatcaa agaagagctg gttgatacga tcttcgatca gattaatgtt
    17761 ctggttggtt aacaccgaaa tagaaataag gtccgctggc aactgttcca attcaatctt
    17821 ttgttccaaa tctgttttat tcagcaatat aatgcggtta ctgccctgac tgagatttaa
    17881 caaagcccgg tcttggtcag tcagtttttc agaagcattc agcacaagaa gaacaaggtc
    17941 agcttcttga agagcttttt tagaccgttc aactccgatt tgttcgacca gatcatctgt
    18001 ctcacgaata ccggccgtat cgacaagttt tagaggaact cccttgatat taacgtattc
    18061 ttcaatgaca tctcgggtgg ttcctgcaat atcagtcaca atagccttgt cttctcgcaa
    18121 caaattatta agtaagcttg acttaccgac gtttggacga ccaataatag ctgttgataa
    18181 gccctcacgc agaattttac cgcgtttagc tgttcgaagg agattttcca aaaggctttg
    18241 gaattcttgt gttttttcac gtagcagagc agtggtcatt tcttccacat cgtcgtattc
    18301 agggtagtca atattaactt cgacttgagc taaggtgttg agaatttctt gtcgggtgtc
    18361 attgataagc tgggaaaggg agccatccag ttgcttgact gcaatcgtca tagccttgtc
    18421 tgttttggca cgaataatgt ccatgacagc ctcagcttga gtcaaatcaa cacgaccatt
    18481 taagaaggca cgtttggtga attcgccagg ctctgccatt ctagcgcctt ggcgaatcaa
    18541 tagttgcaag atttcatttg tcacagcaat accaccgtgc gtattgattt caaccacatt
    18601 ttcacgggta aaggttttgg gggctagcat gactgacacc ataacttcat cgataatagt
    18661 tcctgtctta ggatcaatga tatggccata gttaatggtg tgtgaggcga cttgctctaa
    18721 gttctttccc ttaaaaacag attgtgcaat ggcaagcgca tctgtcccgg atagacgaac
    18781 aatgccaata gctccttcac caagaggggt tgaaatggcg gtaattgtat caaattcttt
    18841 agttatactc atgccctcta ttttaaatca agtcctagta gaaagcaagg tattattttg
    18901 tatagaaaat aggactagca ccattttgag tttag
//
LOCUS       DATWVB010000033        17909 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.033, whole genome shotgun sequence.
ACCESSION   DATWVB010000033 DATWVB010000000
VERSION     DATWVB010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17909
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.033"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(311..1756)
                     /locus_tag="VCX65_001319"
     CDS             complement(311..1756)
                     /locus_tag="VCX65_001319"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEP5053779.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            complement(1939..2649)
                     /locus_tag="VCX65_001320"
     CDS             complement(1939..2649)
                     /locus_tag="VCX65_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEP5053780.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            complement(2780..3277)
                     /locus_tag="VCX65_001321"
     CDS             complement(2780..3277)
                     /locus_tag="VCX65_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEP5053781.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVRKDMAKLRASSLIPDDVVINGAVYDVATGKM
                     TQVME"
     gene            complement(3466..4827)
                     /gene="radA"
                     /locus_tag="VCX65_001322"
     CDS             complement(3466..4827)
                     /gene="radA"
                     /locus_tag="VCX65_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEP5053782.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKA
                     VFS"
     gene            complement(4908..5354)
                     /locus_tag="VCX65_001323"
     CDS             complement(4908..5354)
                     /locus_tag="VCX65_001323"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEP5053783.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            complement(5464..6231)
                     /locus_tag="VCX65_001324"
     CDS             complement(5464..6231)
                     /locus_tag="VCX65_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEP5053784.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWAKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            complement(6349..8133)
                     /locus_tag="VCX65_001325"
     CDS             complement(6349..8133)
                     /locus_tag="VCX65_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053785.1"
                     /translation="MKTARFFWFYFKCYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLVQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTVTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAIVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            complement(8136..9842)
                     /locus_tag="VCX65_001326"
     CDS             complement(8136..9842)
                     /locus_tag="VCX65_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053786.1"
                     /translation="MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPILFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIESGQMVGIVGATGSGKSTLAQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            complement(9835..10284)
                     /locus_tag="VCX65_001327"
     CDS             complement(9835..10284)
                     /locus_tag="VCX65_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP5053787.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            10582..11598
                     /locus_tag="VCX65_001328"
     CDS             10582..11598
                     /locus_tag="VCX65_001328"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEP5053788.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     HNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            11631..12530
                     /gene="galU"
                     /locus_tag="VCX65_001329"
     CDS             11631..12530
                     /gene="galU"
                     /locus_tag="VCX65_001329"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEP5053789.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(12629..13300)
                     /locus_tag="VCX65_001330"
     CDS             complement(12629..13300)
                     /locus_tag="VCX65_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEP5053790.1"
                     /translation="MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVL
                     SGVMGNAFTFWLSPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGIVGGVLLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVL
                     VLGFL"
     gene            13988..15496
                     /locus_tag="VCX65_001331"
     CDS             13988..15496
                     /locus_tag="VCX65_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP5053791.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKVLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIGNFITSTIPSYKVELSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLFGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            complement(15845..17194)
                     /locus_tag="VCX65_001332"
     CDS             complement(15845..17194)
                     /locus_tag="VCX65_001332"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEP5053792.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKEEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKLEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
     gene            complement(17650..>17909)
                     /gene="speG"
                     /locus_tag="VCX65_001333"
     CDS             complement(17650..>17909)
                     /gene="speG"
                     /locus_tag="VCX65_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
                     /protein_id="HEP5053793.1"
                     /translation="QFTLQEFDFKIRKFLMEKYNIYDSESRYTSGSLFLATKDSKHYE
                     VDLFNKDDKLLSRDSFFKRYKDNKIFNSEEISHFDIYLKTH"
BASE COUNT         5458 a         3801 c         3198 g         5452 t
ORIGIN      
        1 tgaatactaa actagtctct ttcagcatat accaaaaaaa tattgtacac taattgattc
       61 ataaaaacca tttctttaaa tcacactaat caaaacctca ccgtttgctg tcattatcac
      121 gtaagcatct caccacctct ctttcaaatc caatctccaa aatagaaata aactatacta
      181 ttttttactt taccaaggta gcaagctcag ataacgataa aaaagactga agaacttaat
      241 cttcaatctt tcgttgtcgt gactttttaa ctccttaaag cgtttaaaaa taaaggtgaa
      301 cgatacagcc ttatagcatg tttttgatgt gctcaatgga tttatcacgt cccaataaat
      361 aaatcgtatt tggtaattct gggccatgca tttcaccaga tactgcaata cgaataggca
      421 taaagaggtt tttccctttg attcctgttt ctttttgaac agccttaatt tgtgggaaaa
      481 tattttctgg tttgaagtct tcatctgaca tagcttccaa cttagccttg aaagcttgca
      541 agactgtcga aactgtttca cctgccatca cttctttttc ggcttctgtt aattcaggga
      601 aatcagaaaa gaaaaggtca gtcaatggaa taatctcatc tgcagatttt aattgaggtt
      661 tgtataattc tactagcttc tcagcttttt ctgtcaaacg gcctgcctct tcaaggaaag
      721 gtttgcagag ggcataaact gtttcaaaat ccgcatgttt aagatactca ttgctcatcc
      781 aatccatttt cttctggtca aaggcagctg gcgacttgct aaggcgattt tcatcaaaaa
      841 gggcaatcag ttgctcacga gagaagattt cctcttctcc gccaggattc cagccaagaa
      901 gggcgatgaa gttaaagaca gcttcaggca tataaccttt tttgcggtaa tcttcaatga
      961 attggagggt attggtgtcg cgttttgata attttttacc cgtttcagaa ttgatgataa
     1021 gagtcatatg accaaactct ggcgcttccc agccaagagc ttcatagacc atcaattgtt
     1081 ttggcgtatt ggcaatatgg tcatcgccac ggataacgtg agaaatttgc atatcatgat
     1141 catcaacaac aacggcaaag ttataagttg ggtagccatc tttcttttga ataacccagt
     1201 caccaccgat gttaccacct tcaaactcga tatcaccttt aaccatgtca gtccatttgt
     1261 aaataccgga ctcattaaca gcaagacgga ctgttggaac gatacctgct gcttcacgct
     1321 cagcaatgta cttagctttt tcgtcagctg acataccaat aaattcattg atatagcgag
     1381 gcgtttcgcc agctgcttct tggcgttcac gctctgctgc caattcttcc tcagtcacgt
     1441 aagacttata ggcttttcct tcagctaaca attgatcaat atattgttga taaagtgcta
     1501 gacgttcaga ctggcggtaa ttttcatgcg tttctgggct ttcatcccaa tccattccta
     1561 accattttag gttttcaagt tgagaacgtt caccatcttc aacatgacgt ttacggtcag
     1621 tatcttcaat acgaatgata aaagtacctc cgtgacgacg ggcataaagg taattaaata
     1681 gggctgtgcg ggcattcccg atatgtaaaa gccctgttgg acttggtgca taacgcacac
     1741 gaattggttt agacatgctt cttctcctgt tacatatatc actcagaaac ctgtggcacg
     1801 aaaaacaagc aacaaatgat gatttgagct tgccaagacc ttttcagact tcttctaaaa
     1861 tctttcttat tatagcatat tttacttgct taggcgaaaa aaaatcagcc ctaaaaagct
     1921 gattttatgt tattttgact aatttgaact agttggtaga taacgtttaa gagtcccagc
     1981 aaattgctca aggttaagac tttggatata aatctcacca tgacctctaa aggtattaac
     2041 aactccttca cctgtaccaa ttgactgcat aaagccattt tctaaatgaa tatcataatc
     2101 aagttctctg ctccatgcta caacatgggc attatcaata gtcattgtgc caccatcaag
     2161 tgtgattttc ttgatagatc caaacgagtt agcaagtaag gtaccaaggc cttcagttgt
     2221 catgacaaaa agtccgcctt gaccaccaaa aagtgctttt ccaatatttt gacgttccat
     2281 tttgtactgt gctgaaccat ctagggctag aaaggcacca tcatttagac gatattgttt
     2341 ttcacctagt tctaaagcaa caatctgtcc tggtgtattg ggtgctaatg ctaatttacc
     2401 atctccattt gacatagctt gtgtaatgaa cattgattca ccagaaacca tggaacggcc
     2461 gatggctcca actaattttc ctaaaccaga tcccttacca tttaatttgg tattcaaggt
     2521 tacattctca gtatgataaa ccatacttcc ttgttgtaag taaactgatc ccccatgttc
     2581 cagatcaatc tcaactagtg gaaattgcat gttttgatca atcgtaaatc tcattctatt
     2641 gtcgaccatc ttactctcct tgtttgtatg aataacttga tacaattatt ataacgcttc
     2701 cctatttctt tgtctaatat tttcaataat ttttaaaaat aaaaaagagc tgaattcagc
     2761 tctacaactt ggctactaac tattccatta cttgtgtcat ctttccagta gccacatcgt
     2821 agacggcacc gttaataacg acatcatcag ggataagaga ggaggctctt agcttagcca
     2881 tatccttgcg gacactgtct tccacatctt ggaagggaag gaaatcttgc cctgaaacat
     2941 ccacacctaa gtgctcatga atatgcttgg caaagccttc attagtaaaa gtctgcgcgc
     3001 cacaatctgt atggtggaga accacaatct ctcgcgttcc catttgctgc tgagaaataa
     3061 ccagcgaccg aatcatgtct tcggtgacac gtccgccagc attccttaaa atatgagcat
     3121 ctcctagagc cagccccaga gcttgggcca catgtagccg tgaatccata caagtcacaa
     3181 tcgctacttt agtcttgggt tttaagggca gatgagctgt cccatgcaag gccacataag
     3241 cctgattggc agccataaaa tgttcaaaat aagacatcaa taaactcctt ttgagaaaca
     3301 gcagagctat ttttgctgtt agtttgtctt atcttaacat cttttatgga aaatagctgg
     3361 attaacctct tagacggtcg gtatcgttcg aaaagttaaa aaaacaaatg attgggatac
     3421 tttcttgaca aatttcctcc tcatttgctc ttagtttctg atcctctagc taaaaactgc
     3481 ctttaaaacc tgaccaaccg tagtcactcc aacaacctca ataccttgag ggatatcaat
     3541 gccttgcaag gcatttttag gagcatagac cttggtaaag ccaagctttg ctgcttcatt
     3601 aatccgttgc tcaatacggg tcactcgccg aatctcacct gttaacccga tctcgcctaa
     3661 gaaagcttct tgagggctgg ttggtttttc cttataactg gatgcgatag ccacagcgac
     3721 tgccaaatca atggcaggtt cgtctagttt gacaccacca gccgacttga ggtaggcatc
     3781 ttgattttgt aagagtaaac cacaacgctt ttctaaaact gccattatta ggcttacgcg
     3841 attgaaatca agtcccgtag tggttcgtct ggcattgcca aaaacggttg gtgtcactaa
     3901 agattgcacc tctgctaaga taggacgact tccttccatc gttacaacga cagccgatcc
     3961 tgttgcccca tctaagcgtt cctctaaaaa gacttgacta ggatttaaga cctctaccaa
     4021 gccgccagac tgcatttcaa agatgccaat ctcgttagtg gagccaaagc ggtttttcac
     4081 agcccgaaga atgcgaaagg tgtgatgcct ttccccttca aagtagagaa cggtatccac
     4141 catgtgttct aacatacgag gcccagccaa ggttccttcc ttggtgacat gacccacaat
     4201 aaaggttgca atgttgttcg tctttgcaag ctgcatcaat tctgcagtga cttctctcac
     4261 ctgactgact gatccttgaa cacctgtaat atcagggctc atgatggtct gaatggagtc
     4321 aataattaaa aaatctggtt taatattttc aatttctgtg cgaatagctt gcatattggt
     4381 ttcggcatag aggtaaaatt cattgtcaat atcacccaga cgctcactcc gcagtttaat
     4441 ctgctctgct gattcttccc cagacgcata gagaaccgtt cccttattag cgagctgcgt
     4501 agatacctgc aagagtaagg tggattttcc aatacctgga tcaccaccaa ttaaaatcaa
     4561 gcttccagga accacacccc ctccaagaac tctattaaat tcagacatgt cagtctgtgt
     4621 tctgtgataa ctaatattat ccacatcttt tagtttaacc ggtctggact tttctccagc
     4681 tagactaaca cgggcatttt tgacttcttt gacctctact tcttccacaa aagaagacca
     4741 ggccgagcaa tttggacagc gccctaaata ctttggcgac tggtagccac actcctgaca
     4801 gataaaggtt gcttttttct ttgccatagt aatctccctc ccctagacaa gacaaaccca
     4861 ctcttaaaga ataggtctac tgtcataagc atttttgtta aatcgcttta ctgccctgtc
     4921 gaaccaaaac cacctgttcg ttcacctctg gcttggtcac catcagcaat taaaaaaggc
     4981 ataaaaaccc cctgaacgat cctctcaccc acagctaatg tcacagggtg atctgtaatg
     5041 ttttgcattt gtgcaaaaat atgtccttca ttagcctcat ttccataata atctgcatca
     5101 atcacaccta ctgaattaat caggataatc cctttttttc gtggatttga cgaacgatca
     5161 tagaggtaaa gcacctcacc atcttgcatg taggccttaa cccctgttgg taccaactta
     5221 atctcccctg gggcaatggt tacagcctca gcaacagaca ggtcataacc agctgcatga
     5281 gtcgtctcac gttttggtag taaatcagga ttagtaaagc ttgaaacaag ctcgaaacca
     5341 cgaatttttg tcattatgat aggtatatcc tttcaagtca atcatatcct cttattatag
     5401 actattcgta aaagaatagc aaaaaggcgg tcaactttaa acggaccact tttaatcatg
     5461 ccatcacatc tcatccccac gataactaaa gcggatgtgg gtgaaatcat tatccaaatc
     5521 cttgtctgcc ataaaagctt tggcatcttt tttcacttga accaagtcaa taccttgcat
     5581 tttggcagca tagacacagc cacaatagca ttggcggtaa atgtcatact cctcacacat
     5641 ttcaacggat ctgcgataac cgttgttttt cttgaaatca cttggcaggt atttggtggt
     5701 gtaaaccttt tgcacatcga tgcccacatc attaatggtt tgcgaatttt tatgaggact
     5761 gatggttagg gcactggcaa agtagtcaaa acctagttcc actgcttttt gagcggtctt
     5821 gtctagtcgg taatcaaaac agacacggca acggtcccca ccttctggtt cttcttctaa
     5881 acctcgcact tgtcgaacgt actcattggg gacatagtcc gcttcgagaa actgcacggt
     5941 gttgcctgtt ttagcgttga actcggagac aaactgttgt gtcacatagg ctctgcgatg
     6001 gtattcgtcc ttagggtgaa tattagaatt ggcaaagtaa accgtaatgt cagcaaactg
     6061 cgtcaggtat tctagggtgt aagtggagca tggggcgcag cagacatgca ttaaaatact
     6121 gggacgcacg gattccttag cccaaacctt ggccatctgt tgcatgaccc tgtcataatt
     6181 tatcttttga ttgggattca tgttagcgag aatctcttgt aaatcaatca ttgtggctac
     6241 tttctaattg ttttttctct tgcttgctat tataccatat caggaaagaa agcttgactg
     6301 ctttattgtt caccaaaaaa ctccgctaag acgcggagct gataccatct attcaaagac
     6361 aaattgattg tgatacaatt cggcataaaa gcctttttga tgcaatagct catgatgatt
     6421 tccttgctca atgaccttac catctttcaa cacaataatg tgatcggcat ttaaaatggt
     6481 tttgaggcgg tgagcaatga caaagctggt tcgacctgcc acgatagctt ccatggcccg
     6541 ttgaatttta ctttcggtaa ctgtatcaac atttgaagtg gcctcatcca aaatcaacac
     6601 ttcagggtca gtcagtagtg tcctagcaat agaaatcaac tgcttttgac ctgttgaaaa
     6661 gacattgtca tcatctgaga cataggtatt gtaccctttt ggtaaggaca tgataaagtc
     6721 atgaatatgg gtcgcacgcg cagcagtttc aaccatgtct tgactaatgg tctgatcacc
     6781 aaaacgaata ttatccgtaa tggttcctga aaaaagaact gactcttgca acacaatccc
     6841 taccttttga cgaagactat ccaaatcgta gtcacgaata tcacggccat caaaggtaat
     6901 cgaacctgca tccacatcgt agaaacggtt aatcaagttc ataatagtgg tctttccaga
     6961 acctgtcggt ccaaccacgg caatcatttt gcccttgggt gcaacgattg acacatctga
     7021 taaaactttt tgcccaggaa gatacccaaa atcgacgtgg ttaattgcca ctgcttcttt
     7081 taagctggtg aacgctggtg cattttgtgg acgaacttct tcggtttcat caaacatttc
     7141 ttgaatacga tgagcaccgg taaaggccag ctgcaattct ccccaactag acgcgatttg
     7201 catcatgggt tggtaatatt gctgggaata ttgtacaaaa gtaaccacta aaccaagcgc
     7261 tgccgctgct ggcatagatt tgtcactgag gacaattgtt gaaccgacaa aaatcacgat
     7321 agccgtgtta ataaggctca ttccattcat gactggaaat aattgtcctg agaacagacg
     7381 gcgtttgaag gtggcttgtc gaaccctttc gttatgtttt aaaaaggctg tcaccgtatc
     7441 ttcttggaca ccttgtacaa taatagcctt ttgtcctgaa atggtttcat ccataaaagc
     7501 atttaaagca ctgacttctt gctgttggat attggtgtat tttcttgcca aacggatgtt
     7561 aatcactaaa aaaatgagag caactggggt tgatgcgatg gttaacaaag ctaaacggct
     7621 atcttgccta aacatcatcc agaccaggcc gatgtaaagg gcaatattag tcaccacttg
     7681 aaccaaggat tggttcagcg agttttgaat attatccaaa tcactcgtga aacgagaaag
     7741 aatctcccca tctttatggc ggtcaaaaaa ggcgacggtt aaacgttcta atttaccaaa
     7801 caagcccttg cgcatgcggt tggtcgaatg tgagacaaca cgtgtgagta agaaactata
     7861 tattagatta gctaaaacag taaagaaata agtcatcaaa agcttaaaca tcacggcatt
     7921 aaaagctgat aaatcagggc taaaatgtgt ctgaccactc atcttagcaa cgtaataagc
     7981 ctgaccgatt tttcccaact cagtcaagga ctcccctaag aagacaggag cttttacttg
     8041 taaataagtt gctaagataa cggcaacagc aatgacagta aacgagaaac gatagcattt
     8101 aaaataaaac cagaaaaaac gtgctgtttt catcactact cctcccttcc tttttgtgtc
     8161 tcataaattt cacgataaat cgcattatta gccaccaact ctgcgtgtgt tccttctcca
     8221 attaactgtc cttggtcaag gactaagatc ttatctgcct taactaccga tgaaattttt
     8281 tgagcaacaa taactgtagt tgtaccttct aatttatgac ttaaggcttc ttgaacgcgt
     8341 ttttcagatt ttgcatcaag agctgaagtg gaatcgtcta atataagaat tttgggatga
     8401 ttaatgacac cacgtgcaat agacagacgt tgcttttgtc cgccagacaa gttactacct
     8461 cgctcttcaa cttggctctc ataacggcta tccatacgat caataaattc ttttgcttgc
     8521 gcgatttgag cggctttttg catagcatca atatcagctt ttgctgagcc ttggcgaagg
     8581 ttatcagcta tcgttcctga aaagagaata gccttttgca acacgatgga aaccgattgg
     8641 cgcagggttg tttgacttag ggttttaatc ggctttcctc ctaacaaaat ttggccatct
     8701 tgaggatcaa ataagcgagg gatgagctgt gcaagcgttg atttcccaga tcctgttgca
     8761 ccaacgatgc cgaccatttg cccagattca atagcaaaag aaatgtgctt caaggttggc
     8821 tcatcatcat taggatatgt aaaactaaca tcgtcaaata caatgcttcc tgagatggtt
     8881 tcttcctttt cattttcaaa tgtcatggca ggttctgtag acaatatttg cctaattcta
     8941 gccatagaaa caaaagcacg actaacttgc atccccatgg aaccaaccac aataattgaa
     9001 aacataattt gcatcatata agtcatgaaa gaggcaatat tcccaatcac tgttggatct
     9061 gtttcgacca tggtcgaaac aacatttata gaaacataaa ctgccaaata agacaccaac
     9121 attaaagccg gctgcattag tgaaaaacca taaccaatag ataaatttaa cgccaaaaga
     9181 tcattggacg tttctttaaa tttagtgtat tgttgttgtt cttgtacaaa tgatttaacc
     9241 acgcgaacgc cacggagatt ttccttagcg atgcgattaa tcttatccat taaccgttga
     9301 aatttaccaa aacgaggacc catttgacgc atcaccaaac ccatgatgag ggcaattaag
     9361 ataaccatta caacaatgac ccaccataat tgagggaatg tctgaactgc cataataaac
     9421 gcgccaataa aaaggatcgg caaacgaaag agaatttgaa acatcatcat gactaaactt
     9481 tggatttgat tgatatcatt agttagccta accacaagat taccagcatt aaaagcttca
     9541 atattggcat atgaaaagtc ttggattttt cgaaaggtct tctccctcat atcagcagat
     9601 acaccttgag ctattttagc agctaaaacc gtattaatcg ctccagacat taaccctaaa
     9661 agggcaataa taagtaatgg tttcccaacc tcataaattt tctcttgatt attttgaatc
     9721 acagcgctta gcacagattt aagataatgt ggttgcaaga gactacttgc aacaacccca
     9781 ataaccataa aaaatgagcc taaagcatac catttataac gtaagattgc gtctttaagc
     9841 atcgttgtct cctttataag ttagcatatt ttgcttgagc tgttcaatta cttttttcgc
     9901 tgtcagcaac tcttcttttg taatttcttt taaaaaatag tgctcgatat ccttacgaca
     9961 ctcccgcaac aaaggcaatt tatctctacc aacctgcgct aacactactt gcttataacg
    10021 cttatccact tgggaaggca tcacattgat aaacccattt ttgaccatac gtttcactaa
    10081 atgactagca actgactttg agatacgaag ttgtttttca atatctttga caaatatttc
    10141 ttgattttgg tgtttagcta aaaaaacaag aacataacct tgaggacctg ctagatgttc
    10201 tacatcatat ttttttgcaa tctcatcact aatttgttcg atttgatgta tcaattcacg
    10261 taaatcacct atcacttgtg acatctcttc cctccttatt ttctttaata gtttctatga
    10321 taagtatttt agttctctag ataactattg tcaattaaaa tatctttatt tttaaaaata
    10381 agtttccgaa cttaaataac taaaaagaac agggcaaagc catgacaaca gctcacctga
    10441 tgaagcttat taaacaacat tattaatata gctagctctc ttgggaacgc cttattagcc
    10501 aagaccatat accttttcta atagagctaa tcaaggtgtt atgttataat agagtgacta
    10561 gctcttgaag gagaatttag aatgacaaaa caaaaagtag ctattttagg acctggttct
    10621 tggggaactg ccctttctca ggttcttaat gacaatggcc atgacgtccg tttatgggga
    10681 aatattcctg atcaaattga agagataaat accaagcata ccaatagaca ctacttcaaa
    10741 gacattgtgt tagacaaaaa cattacggca actcttgatt taggtcaagc cctatcagat
    10801 gttgatgcgg tgctttttgt tgtgccaact aaagtaacac gattagttgc tagacaagtt
    10861 gccgccattt tagatcataa agtagtggtc atgcatgcct caaaaggtct agaaccagag
    10921 acccacgaac gtttatcaac tatcctagaa gaagaaattc cagctcattt tcgtagtgaa
    10981 gtggtcgttg tatcaggtcc tagtcatgct gaagaaacta tcgttcgcga tattactctc
    11041 atcacggcag cctcaaaaga tattgaagct gcaaagtatg ttcagtccct ctttagtaac
    11101 cactacttcc gactttatac caataccgac gtcatcggag ttgaaacagc tggtgccctc
    11161 aaaaacatta ttgctgttgg agcaggagct ctccatggac ttgggtatgg agataatgcc
    11221 aaagcagcgg taattactcg tgggttagct gaaatcaccc gtctaggcgt caagcttggt
    11281 gctgacccgt taacctacag tgggttatct ggtgttggtg atctaattgt aacaggtact
    11341 tctgtccatt cacgtaactg gcgggctgga gctgcccttg gacgtggtga aaaattagaa
    11401 gatattgaac acaacatggg tatggttatc gaaggcatcg caacaactaa ggtagcctat
    11461 gaaattgccc aagacctcgg agtttacatg ccaattacaa cagctattta taagtccatc
    11521 tacgagggcg ctgatatcaa agaaagcatc ctcggcatga tgtcaaatga atttcgttct
    11581 gaaaatgaat ggcattaagc cattcgtcac taaaataaga ggaggtgctg atgaccaaag
    11641 tcagaaaagc tattattccc gcagcaggtt taggcacacg ttttttacct gcaaccaagg
    11701 cccttgccaa ggagatgcta cctattgttg ataaaccaac tattcaattt atcgttgaag
    11761 aagctctaaa atcaggtatc gaagaaattc ttatcgttac tggaaaatcc aaacgctcca
    11821 tagaagatca ttttgattct aattttgaat tagaatataa tttacaggct aaaggaaaaa
    11881 tcgaacttct aaagttagta gacgagacca cttctattaa ccttcacttt attcgacaga
    11941 gtcatccaag aggattagga gacgcagttc ttcaagcaaa gacctttgtt ggcaatgaac
    12001 cttttgttgt catgctaggt gatgatctga tggatattac aaatccaaat gtaaaaccat
    12061 taaccaaaca attgatcgat gactatgaag aaactcatgc tgcaactatt gccgtcatga
    12121 gggttcctca cgaggatgtc tctaactacg gtatcattgc tcctcaagca aaagcagtaa
    12181 aaggactcta tagtgtggat acttttgttg aaaaaccaca acctcaagat gcacctagtg
    12241 atttggcaat tattggacgt tacttgctca caccagaaat ttttagtatt ttagaaaaac
    12301 aagaacctgg tgcaggcaat gaagttcaac tgactgatgc tattgatacc ctcaataaga
    12361 cacagcgtgt ctttgctcgt gagtttaaag ggaaacgcta tgatgttggc gataaatttg
    12421 ggtttatgaa aacttctttg gattatgccc tgaaacaccc tcaagtcaaa gatgacttga
    12481 aagcctacat catccaactg ggcaaagcac tagagaaaac aaaaccataa aaataaggag
    12541 ggaaaatccc tccttatttt tatggttttt gagtcgtttc atcctactag ccatctgaga
    12601 agtaacagtg ctaaccactc acttattttt ataaaaaccc aagcactaac acaccaacca
    12661 aaataatacc atagctcact aaagccaaca ttcgcttggt tttcttcact gttatcactc
    12721 tcatcttagt tggaaatact atactcagta acacaccacc cacgataccg ccaatatggc
    12781 ctgccatact cacgtttggc ataaaaagat tcatcagtaa attgactaca attaacgtct
    12841 ggtatgactt gcccaaatct ttcaacgctt ggttcttacc caaaaaactc aatactacaa
    12901 tagcagcaaa aagtccaaat aacgacgtcg atgctcctgc agctactgtt tcaggactca
    12961 accaaaaagt aaaggcattg cccataacac ctgataaaac ataaagtaat aaaaaacggc
    13021 gtgaacccca gaggtcttcg acaatttgac caacaaaata tagtgttaac ccattgacaa
    13081 aaaaatgacc aaagccgata tgaataaata tcggagtcac caatcgccac aactgatctg
    13141 gcattgcttt tactagtaat ccaaacatac ctccaacttg ataaatagct tgagcaccag
    13201 ttgctaaatg tccatatacc acttgcattg ctataaaaat taagcctgtt aaccctaaaa
    13261 ggaaaatagt aataggatat cgttttaata accgtgtcat ctaagataaa cctcctaaac
    13321 agcaatatca taaatcgttt gatttggcaa tcgtattggc ccgctgataa gcttgattgc
    13381 taacaacatc cactaataaa gcttgatcat tttgacgttt taagtctaca tccatagttc
    13441 gtaaagacta gaagagttct ttgagaatct cttttttcat catcttctta tcataccata
    13501 aattaggaaa aaggttcaag actgacaaga aattagctct ctcaaaaaag attaaaaata
    13561 aaggcattct aaagaatcat ttaagaaaac tttaaggtta ctatcgtaga atgaaaacat
    13621 cctaaaaagc ggtttaccta aaccgttggg agaataggtt ttccccttgt tttccctttt
    13681 cataaatctc ctgggcacct atcctcgtag gtgccctccc ttgtttaaac ctgaccagtt
    13741 aaccggctgg ttaggttttt aaatttaaaa agtcaacagc aaaaatatga tatcacccgc
    13801 gtgttcttag ctctctcaat tatgggctaa aaacacgcat caatcaatct attgatgaag
    13861 tttgctgctt tttgatgatc tttattgtga ctatactggt aatcctattg attttagttg
    13921 acttttacgg tagattcgct acaatatata ggattataca atttaattta aggagagaaa
    13981 aattacattg ttagattatt atttggaatc cgatattatt gaccagaaaa tcctactggc
    14041 tattttgttg acagaaaaag aactgacgat ggcagcagct tgttctcaaa caactttgac
    14101 tgctttaaaa ataaagcagt atcttcgaca atttaacgcc ttatttaaag ggtacttacg
    14161 tattgagctt attaaatctc gtatttattg tgaggtatta aatgataagc gagaagcatt
    14221 tttttatgat atttttgcct tatcagatac tctaaaagtg ttgacattct tattactaga
    14281 taatcccaaa cacaaatcaa tcgctgttta tacacgaaaa caagggatat cccagtcaaa
    14341 agcttatcgt cttattcata aattaaaaca ttatttacaa gacattggtt taaatattgt
    14401 agacaatact gttatcggag atgaacttaa aatacggtat ttgattgctc ttttacataa
    14461 agagtacggc attatattat atgatataca acctgcagac attgaaacga ttcatgcttt
    14521 tatctttgca gcacaaaaaa acttacaacc ttctgccttt ttagatagac gcttcttgtt
    14581 ttttgatgtg ctgttgatgt tgacttggaa gcgccatcgc tatcctgttc atttgcctca
    14641 tttagctctt tttgaacatc tcaaatcctt gcctattttt gacaatatca aaaccattgc
    14701 cgtggatgag ctagcacctc gaactcgtgt cacattttcg tctgatgatt ttgactatct
    14761 ctttttaatt tatttaacga ctgataactc cttcttgagt gggtactgga caagtcatca
    14821 gcgacaacaa ctttaccatt taatcaccaa agatcccgat tatcatttac taatccatcg
    14881 tcttcaggca ctagttggaa aatattccga tattcatgag catatcccta acttaattcc
    14941 ttttttcaaa agaactctct acaatttaca aactttaatt acctttgatg gttattattt
    15001 tgatcaatat caaggcaaca tgctactact agataagctt gaaaccgtta tcaaagattg
    15061 gctttatgac acaggccgtc aaggcagtat tagttctggt cacttacact tgatgtgttt
    15121 ataccttgag cagatcttgg aaagctctat tgctccaatc aatattactg ttattgagag
    15181 ccaagaaact gttggtaacg ttataggtaa tttcatcacc tcaactatcc cttcttacaa
    15241 agttgaactg tcacgggtca atatcttatc tgataatatt tatccctatg ataaacctgt
    15301 agatctggtt gtgaccagtc agaagctctt gcctttctta aaagaactcg gtgtttttcc
    15361 caaagagacc cgcttgtttg gtttgagttt ggactgtatc caacagcagc gcgaagattt
    15421 aatcaaaacc atcttagcct tgcaccagaa ccactaccaa aaacgtttag aagaactttg
    15481 gagagttcct tcttaatttt ttgacagtcc ctcctagata cttttacagt ctaggggggt
    15541 ctttaaggtt gtcacttgca accttgataa gctctctttt taaccattgc tatttgctta
    15601 gaaacagaac tggaactgtt ttagcggttc aactcctctt gtaggatctt cttccctttt
    15661 ttgaaggttt tatctgaaat ttggcataat aaagtgcgct cccatgttct ggaagcgcac
    15721 tttattatcg cttttactta accttgtatc cacttgatga tggaagtgcc gccccaattc
    15781 ttagattgct tggctaactt ttaagctctt gtacaaggaa gaagtctttt tgactatctg
    15841 ttgattagag gcgagcatta agctctgctg ataatgcttc aaaacctggt tttccaagaa
    15901 gcgcaaacat attacgtttg taagcttcaa cacctggttg atcaaatggg ttaacagcat
    15961 tcatgtagcc tgaaacagcg atggcaagct caaagaagta aatagtgtaa ccaagggtaa
    16021 actcgtcttg agctggaaga gtgacaaaca tgtttggcac gccaccatct gtgtgggcaa
    16081 gaagcacacc atctgtggct ttcttattaa caaaatcaac gtctttacct tgaaggtaac
    16141 caagaccatc taggtcttct gctaattcag gaatgataac atttttacga gggttatcaa
    16201 cacgaataac tgtttcaaag aggttacggt aaccttcttg gataaattga ccaagtgagt
    16261 gaaggtctgt tgagaagtta gctgaagttg ggtaaatccc tttttgatct tttccttctg
    16321 attcaccagc taattgtttc caccattcgc caaagtactg aagagatggc tcgtagttag
    16381 ccaagatttc agtgatgtag cctttacggt aaagcacatt acgaacagca gcgtattggt
    16441 aagcaatgtt ttcagagatt ttgtctgaag aaaggtcttt acgagcagca tttgcccctt
    16501 ccataagagc agtaatatct gcacctgatg cagcaattgg aagcaaacca acagcagtca
    16561 agactgagaa acgaccacca acattatctg gcaccacaaa tgtttcccag ttgttagcgt
    16621 cagcttctaa cttaacagca cccttaactt tgtctgtggt agcgtagata cgtttgttag
    16681 cttcttcttg gccatatttt ttaaccaaaa gttctttgaa cacgcgaaaa gcaatagctg
    16741 gctcagtggt tgtacctgat ttagagatca cgtttactga gaattctttg tcttgaacgt
    16801 actctacaag gtcagctaag taagttgatg aaatagagtt tccagcgtaa agaatttgtg
    16861 gggctttgcg ctctttggca gtttgcaagt tagcaaaatg atgatttaaa aaatcaatcg
    16921 ctgctttggc accaaggtat gacccaccga taccgatcac cacaagaact tcgctgtctg
    16981 ccttaatctt ttcagcagca gtcaagatac gtgcaaattc ctctttgtca tagttttctg
    17041 gaagatcaag ccagcccaag aaatctgaac ctggtccagt tccttcacgc aataacttgt
    17101 cagcttctgt gacttggcct tgtaaaaaat caatttcatg ttgtcccgca aatgactcga
    17161 ggacttttga ataatcaaat gtaatatgtg acatgagttt cgctccctta aaattttaag
    17221 tttcattagt atgataacct tttctatcta atatttcaat ggtttttagt ggttttcacc
    17281 tgtgaaaaag ctaggttttt tgaaaaggtt ttcgtttttt cagacataaa aaatgtgtca
    17341 atgcaagcat attctcatca tagtggtttt ttaagagaaa ataggatttc atatttccta
    17401 aaaatatcat gaaaaaaggc cctgaggccg ctttaccgta ataacttatt ttaaggattt
    17461 tatcatttca acacgggtaa taaccccatc atgcatatga tcaatgcata aagccacacc
    17521 tacaaaggca attgaagccc caatcacctg taaatacttt ctcatgctat cttcttaaca
    17581 ttacttactc tcattatcta aaaatggcaa tcatttgaat acttaaaaag caaagggggg
    17641 agaatagcac tagtgcgttt ttaagtagat atcaaaatga ctaatttctt cactattaaa
    17701 aatcttatta tctttatacc ttttaaagaa actgtctcga cttaaaagct tatcatcctt
    17761 attaaataaa tcaacttcat aatgtttact atctttagta gcaaggaaaa ggctccccga
    17821 tgtataacgc gattccgaat catagatatt gtatttttcc attagaaatt ttcttatttt
    17881 aaaatcaaat tcctgtaaag taaactgtt
//
LOCUS       DATWVB010000034        16029 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.034, whole genome shotgun sequence.
ACCESSION   DATWVB010000034 DATWVB010000000
VERSION     DATWVB010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16029
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.034"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            16..807
                     /locus_tag="VCX65_001334"
     CDS             16..807
                     /locus_tag="VCX65_001334"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEP5053794.1"
                     /translation="MQFKHIIFDVVDDLATLTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGLDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
     gene            884..1318
                     /locus_tag="VCX65_001335"
     CDS             884..1318
                     /locus_tag="VCX65_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP5053795.1"
                     /translation="MEYDKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            1319..2293
                     /locus_tag="VCX65_001336"
     CDS             1319..2293
                     /locus_tag="VCX65_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEP5053796.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVKI"
     gene            2354..2578
                     /locus_tag="VCX65_001337"
     CDS             2354..2578
                     /locus_tag="VCX65_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEP5053797.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            2780..3751
                     /gene="fabK"
                     /locus_tag="VCX65_001338"
     CDS             2780..3751
                     /gene="fabK"
                     /locus_tag="VCX65_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEP5053798.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            3776..4714
                     /gene="fabD"
                     /locus_tag="VCX65_001339"
     CDS             3776..4714
                     /gene="fabD"
                     /locus_tag="VCX65_001339"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEP5053799.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            4704..5438
                     /gene="fabG"
                     /locus_tag="VCX65_001340"
     CDS             4704..5438
                     /gene="fabG"
                     /locus_tag="VCX65_001340"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEP5053800.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPMKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            5453..6685
                     /gene="fabF"
                     /locus_tag="VCX65_001341"
     CDS             5453..6685
                     /gene="fabF"
                     /locus_tag="VCX65_001341"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEP5053801.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMVDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            6687..7187
                     /locus_tag="VCX65_001342"
     CDS             6687..7187
                     /locus_tag="VCX65_001342"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEP5053802.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNSTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            7184..7606
                     /gene="fabZ"
                     /locus_tag="VCX65_001343"
     CDS             7184..7606
                     /gene="fabZ"
                     /locus_tag="VCX65_001343"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEP5053803.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            7638..9002
                     /locus_tag="VCX65_001344"
     CDS             7638..9002
                     /locus_tag="VCX65_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEP5053804.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAH
                     GNIIHLGERDCSLQRNNQKVLEESPSIAIGNTLRHEMGQAAVRAAEAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAISQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            9011..9877
                     /locus_tag="VCX65_001345"
     CDS             9011..9877
                     /locus_tag="VCX65_001345"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEP5053805.1"
                     /translation="MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            9874..10644
                     /locus_tag="VCX65_001346"
     CDS             9874..10644
                     /locus_tag="VCX65_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEP5053806.1"
                     /translation="MTDVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(10877..12154)
                     /gene="serS"
                     /locus_tag="VCX65_001347"
     CDS             complement(10877..12154)
                     /gene="serS"
                     /locus_tag="VCX65_001347"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEP5053807.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRALLVQ
                     SEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRSYMGGETVISPK"
     gene            complement(12546..12905)
                     /locus_tag="VCX65_001348"
     CDS             complement(12546..12905)
                     /locus_tag="VCX65_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEP5053808.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGIGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            complement(13019..13930)
                     /locus_tag="VCX65_001349"
     CDS             complement(13019..13930)
                     /locus_tag="VCX65_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEP5053809.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            complement(13947..14756)
                     /locus_tag="VCX65_001350"
     CDS             complement(13947..14756)
                     /locus_tag="VCX65_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEP5053810.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAATEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGVIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            complement(14845..15837)
                     /gene="manX"
                     /locus_tag="VCX65_001351"
     CDS             complement(14845..15837)
                     /gene="manX"
                     /locus_tag="VCX65_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEP5053811.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
BASE COUNT         4864 a         2891 c         3606 g         4668 t
ORIGIN      
        1 gaaaagagga ttgttatgca gtttaaacac atcatctttg atgttgtaga tgatcttgcg
       61 acattgactt taaaccgtcc agaggtttca aacggtttta atattccaat ttgtcaagag
      121 attctggtag cattagcaga agttaaacgc gatacatctg tgcgtttttt attaattaaa
      181 gccgttggaa aagtgttttc agttggtggt gacctagttg aaatgcaaga agctgttgca
      241 aaagataatg tgcagtcgct agtcaagatt gctgaactgg tacaagaaat ttcttttgca
      301 atcaagcatt tgccaaaacc agtcatcctt tgcgccgatg gagctgtagc tggagcggct
      361 tttaatatag ctttagctgt tgacttttgt atcgctagta ctcaaacaaa atttatccaa
      421 gcttttgtaa atgttggact agcaccggat gccggtggtt tatttctatt gactcgtgca
      481 gtaggactta atcgtgcaac tcaccttgtg atgacaggtg aaggaattac tgctgataaa
      541 ggtctcgatt atgggtttgt ctaccgtacg gcagaatctg ataaactaga caaagtttgt
      601 cttcaacttt taaagcgatt gagacgtggc tcttcaaatt cttatgctgg aatgaaatca
      661 ttggtctggc aaagcttttt cacaggatgg gaagattatg ctaaggcaga gcttgctatt
      721 caagaggagc tagctttcaa ggaagatttt aaagaaggtg tcatagcttt tggagaaagg
      781 cgccgaccaa attttcaagg taagtaagac agctgttgct tgcaaaatac tttgaccttt
      841 gatataattt gattgtcaaa gtttattgct aggaggtgtt tacttggaat atgacaaaat
      901 taaccaatac ttagttgata ttttcaaccg gattttggtt attgaagaaa tgagcttaaa
      961 gacgagtcag tttaatgatg tctctttaaa agagatgcac actattgaaa ttatcggcaa
     1021 atatgatcag gtgactccaa gtgatatcgc cagagaatta atggtaacgt tagggacagt
     1081 aacgactagc ttaaataaat tagaagcaaa aggttatatc gcaagaacgc gatcacgctc
     1141 agataggcga gttgtttacc tgtcattaac aaaaaggggt cgacttttgg accgcctcca
     1201 tgcaaagttc cataaaaata tggttggaca tgtcattgct gatatgagtg atgaagagat
     1261 gcaggcattg gtgcgtggac tagggaatct acatcaattt ttggaggatt tggtttaaat
     1321 gattttttct aaaatcagtc aggtagccca ctatgttcca cagcagttag tgactaataa
     1381 tgatttagct agcataatgg acactagtca tgagtggatc ttttctcgaa caggaatagc
     1441 agaacgccat atttctagag atgaaatgac tagtgaccta gctattcagg ttgctgatca
     1501 gcttttaact cagtctgggt taaaagctga tgctattgat tttattattg ttgcaactat
     1561 cagccctgat gccactatgc catcaacagc tgcgaaagtt caagcagcta ttgcggctac
     1621 aagtgctttt gcttttgata tgactgctgc ttgtagtggc tttgtctttg ccttggctat
     1681 ggcagataag cttattgcat caggtgccta ccaaaacgga atggtaatag gtgcagagac
     1741 tttatctaag ttagtaaact ggcaggatcg agcgacagcc gttctttttg gagacggagc
     1801 tggtggcgtg ctactggaag ccagtaaaga taaacatgtt ttagcggaaa cattacacac
     1861 agatggtgcg agatgtcaga gtttaatttc aggagaaact agtctttcat ctccgtactc
     1921 aattggcaaa aaagccatag cgactattca gatggatgga cgtgccatat ttgattttgc
     1981 gattagggat gtgtcaaaaa gcatcctcac actaatggcg caatcagata ttacaaaaga
     2041 tgacatagac tattgtttat tgcatcaagc taatcgtcgt atacttgata aaatagcacg
     2101 caagattgat gttcctcggg aaaaattcct tgaaaacatg atgcgttatg gtaatactag
     2161 tgctgctagt atcccaattc tcttgtcaga ggctgttcaa aagggacaga ttaggttaga
     2221 tggtacccaa aaaatcttac tttccggttt tggtggaggt ttgacatggg gaagtctaat
     2281 tgttaaaatc tagttattca tgtgcctagc acatttataa aaacaaattt atatttttta
     2341 aggagaaata aacatggcag tatttgaaaa agtacaagaa attattgttg aagaacttgg
     2401 taaggagaca gaagaagtaa cgctagaaac tacatttgat gatttagatg cagattcact
     2461 tgatgttttc caagttattt cagaaattga agatgctttt gatattcaaa ttgaaacaga
     2521 agaaggatta aatactgttg gtgaccttgt tgcttacgtt gaggaaaagt caaaataagg
     2581 ataaaagtga caagtaacat cagaagtcta tgaaaagctt actgctgtta tgttcatgtt
     2641 catcactaaa aaaaacaata agtattaatc aaaccattag ggtgggatta gactcttttt
     2701 aggatctagc tcgctctttc ttcttactat aatagtttga ttatcaaatt attctcctta
     2761 ttttttatag aaagttatta tgaaaacacg tattacagaa ttacttaata ttgattaccc
     2821 catttttcaa ggaggaatgg cttgggttgc tgatggtgat ttagcaggtg cagtttctaa
     2881 tgctggtggt ttaggcatta taggtggtgg caatgctccc aaagaagtcg ttaaagctaa
     2941 tattgatcgt gtcaaagcta ttactgatag accttttggg gttaatatca tgcttttatc
     3001 tccttttgct gatgatatcg ttgatctggt cattgaagaa ggtgttaaag tagtaacaac
     3061 aggcgcagga aatccaggaa agtatatgga aagactgcac caggcgggta taatcgttgt
     3121 tcctgttgtc ccaagcgttg cgctagccaa acgtatggaa aagcttgggg tagatgcagt
     3181 gattgctgag ggtatggaag ctggaggaca tattggcaag ttaacgacta tgtctttagt
     3241 aagacaagtt gttgaagcgg tttcgattcc tgtcattgcg gcaggtggta tagctgatgg
     3301 tcatggtgca gcagcagcat ttatgttagg agcagaggct gttcaaattg gaactcgctt
     3361 tgttgttgct aaagaatcca atgcccacca aaattttaaa gataaaatct tagcagcaaa
     3421 agatattgat acggtgattt ctgcgcaggt tgtgggccac cctgtccgct ctattaaaaa
     3481 taaattgacc tcagcttacg ctaaagcaga aaaagcattt ttaattggtc aaaaaacagc
     3541 tactgatatt gaagaaatgg gagcaggatc gcttcgacat gctgttattg aaggcgatgt
     3601 agtcaatgga tctgttatgg ctggccaaat tgcagggctt gtgagaaaag aagaaagctg
     3661 tgaaacgatt ttaaaagata tttattatgg tgcagctcgt gttattcaaa atgaagctaa
     3721 gcgctggcaa tctgtttcaa tagaaaagta gataaacaca tgaaggataa tgataatgac
     3781 aaagacagcc tttttatttg ccggtcaagg tgcccaaaaa ttagggatgg caagggattt
     3841 ttatgataac tttgctattg taagaaaaac ctttgatcaa gctagtcaag tattgggata
     3901 cgatttgcgc cgtttgattg atagtgacga gttaaaactt aatcaaacta gctatacgca
     3961 accagctatt ttgacatcat caattgctat ttaccgtgtt ctgggcttac atcacgttaa
     4021 accggatatg gtagctggtc tttccttagg agagtactca gctttggtag catcaggggc
     4081 actctctttt gaagataccc tatccttagt agctaagaga ggccgcttga tggaggaagc
     4141 agcaccacaa ggatctggaa agatggttgc cgttatgaat acagacgtgc aagtcatcga
     4201 agaagtctgt caaatagctg ctaaacatgg agtggttgct ccagcaaact ataatactcc
     4261 tagtcaaatt gtaattggtg gtcagacaga tgctgtgaac gtggcagttg aacttttaaa
     4321 ggaaagggga gttaagcgtt taatcccttt aaacgtgtca ggtcctttcc acactgcttt
     4381 gttagaacca gctagccgct tgttggctaa agagttggaa agatacaact tcagtgactt
     4441 caagattcct ttggttggta ataccgaagc taatattatg gaaaaagatc gtatcccaga
     4501 actattagcc cgtcaagtca tggagcctgt tcgtttttat gacagtgttg cgactttagt
     4561 agaaagtggc ataacacaat tcattgaggt aggaccaggt aaggttttga caggttttgt
     4621 gaagaaaatt gataaaaatt tactatgtac tagtgttgaa aacatggtaa gcttacgttt
     4681 atttttagat agagaggata ttcatggaaa ttaaaggaaa aaatatattt atcacaggct
     4741 caacgagagg tatcggttta gcaatggctc atcaattcgc cagtttagga gctaatattg
     4801 tcttaaatgg tcgctctgct atctctgagg agcttgttgc tagttttact gactatggtg
     4861 ttacagttgt taccatctct ggggatgttt cagaagcatc agaagctaaa cgtatggtca
     4921 atgaagctat cgaaagttta ggttcgattg atgttttagt taacaatgct ggcattacta
     4981 atgataaatt gatgcttaaa atgacggaag aggattttga gcgcgtcttg aaaatcaatt
     5041 tgaccggtgc ttttaacatg actcaatcag tgttaaaacc aatgatcaag gcccgccaag
     5101 gagcaattat taatgtctct agtgtggttg gtttaacagg caatattggg caagcaaact
     5161 atgctgcttc taaggcagga atgattggtt ttaccaagtc tgttgcccgt gaagttgctg
     5221 ctcgtaacat ttgcgtgaat gctattgctc caggatttat cgagtccgac atgacaggtg
     5281 tccttcctga aaaaatgcaa gagcaaatct taagtcaaat cccaatgaaa cgtattggaa
     5341 aagctcaaga agttgctcac ttagcaagct tcttggtgga acaagattat attacgggac
     5401 aagttatcgc tattgatggc ggtatgacaa tgcaataagg agacgtagtg aaatgacatt
     5461 taaaagagta gtggtaacag gttatggtct aacatctcca atcgggcatg atcctgaaac
     5521 gttttggaac aatctgaaag ctggccaaat tggtattggt cctattacta aatttgacac
     5581 gactgattat gcagtcaaga atgctgctga aattcaggat tttccatttg acaaatactt
     5641 tgtgaaaaaa gatttgaacc gtttcgatag atattctctt tatgctcttt acgcagcgaa
     5701 agaggctatt aatcatgctg atttaaatat tgagatggtt gattccgatc gatttggcgt
     5761 tattgttgct tcaggtattg gtggaattgc ggagattgaa gagcaggtga ttcgcttaca
     5821 tgaaaaaggg ccaaaacgtg tgaagccaat gacgttgcca aaagcgctac caaatatggc
     5881 tgcaggaaat gtcgccatgt ctttaaaagc tcaaggagta tgtaaatcaa ttaatactgc
     5941 ctgcgcttct tcaaatgatg cgattgggga tgcctttcgt gccattaaat ttgggactca
     6001 agatgtgatg atagttggtg ggtcagaggc ggccataacc aagtttgcca ttgctggctt
     6061 ccaaagttta acagctctct caacaactga agatccaagc agaagctcta ttccatttga
     6121 taaagaccga aatggtttta tcatgggaga aggatcagga atgcttgttt tagaaagcct
     6181 agaacatgcg caagaacgcg gggcgacaat cttagcagaa attgtgggtt atggaaatac
     6241 ctgcgatgcc taccatatga catctccaaa tcctgaggga ttaggagctc gtaaagccat
     6301 ccacttagcc ttacaagaag ctggtattga agccagtgct attaattatg tcaatgcgca
     6361 cggaacttca actccagcta atgaaaaagg agagagtcaa gcaattgtag ccgttcttgg
     6421 taaggatgtt ccggtgtctt caacaaaatc gtttacgggt caccttcttg gagcagcagg
     6481 cgctattgaa gctattgcca ctatcgaggc tatgcgtcat aactatgttc cgatgacggc
     6541 tgggacacaa gctttatcag aggatatcga agcaaatgtc atctttggag aaggaaaaga
     6601 aacagctatc aactatgcca tttcaaatac ttttggattt ggtggtcata atgctgtatt
     6661 agctttcaaa tgttgggagg agtaggttga atattcaaga aatcaaagat ttgatggctc
     6721 agtttgatac ctcaagccta cgtgaatttt tattcaaaac aaatgaaggt gagctaatct
     6781 ttagtaaaaa cgaacaacac ctcaatgcat cgacatcaaa tcaagaacat gctgtgcctg
     6841 taccacaggt acaacttgtt ccgaattcaa ctgcttcgga agcgtccagt ccagcatcag
     6901 ttaaggatgt tcctgtagag gagcaaccac aagcagaatc ttttgtagca gaaggtgata
     6961 ttgttgaaag tcctttagtc ggtgtagcct atcttgcagc tagccctgac aagccaccat
     7021 ttgtggcagt cggagatact gtaaaaaaag gacaaaccct tgtgattatc gaagccatga
     7081 aggtgatgaa cgaagtgcca gcgccatgtg atggtgtgat tacagaaatt ttggtatcaa
     7141 atgaagatgt cattgaattt ggacaaggat tggtgcggat caaatgatgg atattagaga
     7201 aattcaagcg gctttgcctc atcgctaccc aatgttattg gttgatcgtg tgttagaagt
     7261 gtcggacgac catatcgttg ccattaaaaa tgtgactatt aatgaacctt tctttaacgg
     7321 gcattttcct cactatcctg tgatgccagg tgttctgatt atggaagctt tggctcaaac
     7381 agctggtgtc ttagaattgt caaaagaaga aaataaaggc aagttggtct tttacgctgg
     7441 aatggataaa gtgaagttca aaaaacaagt cgtccctggt gatcaacttg tgatgacagc
     7501 aacctttatc aagcgtcgcg gtaccattgc tgtcgttgaa gccagggcag aagttgatgg
     7561 caagctagca gcaagtggaa cattaacctt tgcctgtggg caatgagaat gattgttctg
     7621 cggaggaaga aacccttatg tttaaaaaaa tcttaattgc taatcgtggt gaaattgcag
     7681 tgcgtatcat tcgtgctgca cgagaattag ggatttccac agttgcagtt tattcggaag
     7741 cggataagga agctctgcac acgatattgg cggacgaggc tatctgtatt ggtcctgccc
     7801 gttccaagga atcctatctt aatatgaatt ccgtcttgtc agcagctatt gtgacaggag
     7861 cccaagcgat tcacccaggg tttggctttt taagtgaaaa ctcaaagttt gcgaccatgt
     7921 gtgaagagat gaatattaaa tttatcggtc catccgcatc ggttatggat aaaatgggtg
     7981 ataaaatcaa tgctcgttct gaaatgatta aggcaggagt gcccgttatt ccagggtcag
     8041 atggtgaagt ttataacgct caagaagcct tagctattgc caataagatt ggttatcctg
     8101 tcatgctaaa agcatcggca ggtggtggag gtaaagggat tcgtaaagtg gagacagaag
     8161 cagatttgga ggcggctttc aatgctgcca gtcaagaagc tttgggagct ttcggaaatg
     8221 gcgccatgta tttggaaaaa gtaatttacc cagctagaca tattgaggtg caaattttag
     8281 gagacgctca cggtaacatc attcacttgg gagaacggga ttgctccttg caacggaata
     8341 atcaaaaagt cttggaagaa agtccatcca ttgctattgg caataccctc agacacgaaa
     8401 tggggcaagc agcggttaga gcagctgaag ctgtagccta tgaaaatgcg ggaaccattg
     8461 agtttttgtt ggacgaagac agcgagaaat tctatttcat ggaaatgaat acccgtatcc
     8521 aagttgagca tcctgtcacc gaatttgtga caggagtgga tattgtcaaa gagcaaatca
     8581 aaattgcagc aggtcagcct ttggcgatta gtcaagaaga catcactatc acgggacatg
     8641 ctattgaatg tcgtatcaat gctgaaaata ctgcttttaa ctttgcaccg agtccaggaa
     8701 agattacaga cttgtatatg ccaagtggtg gtgtaggact acgagttgat tcagcagttt
     8761 acaatggcta tgccattcct ccttattatg acagcatgat tgctaaaatc atcgttcatg
     8821 gaagcaatcg atttgacgct ttgatgaaaa tgcaacgtgc cttagttgaa ttggaaattg
     8881 aaggcattat caccaataca gacttccagc tcgatttgat ttcagataag cgagtgattg
     8941 caggagatta tgatacctct ttcttgatgg aaacgttcct gccacattac aataaagatt
     9001 aggagaaaat atggctttat ttcgtaaaaa agataaatac atccgtatta ctcccaataa
     9061 ttccctcaaa ggatctgtca gccataatgt cccagaagtt ccagatgaac tctttgcgaa
     9121 atgcccagct tgtaagcaca tgatttataa gaaagatttg ggattggcaa agatttgccc
     9181 aacctgttct tacaatttta ggatttctgc ccaagagcgg ctgaccttaa cagttgatga
     9241 aggctctttc caggaattat ttacaagtat tgaaaccaag gatccgttac gctttccagg
     9301 ttatcaggaa aaattacaaa aagccaagga aacaactggt ctgcatgaag ctgttttgac
     9361 agggaaagct atggttaaag gacaacaaat tgctcttgct attatggatt ctcactttat
     9421 tatggctagt atgggaactg ttgttgggga aaaaattacc cgattgtttg aattggctat
     9481 cgaagaaaac ctgccggtgg tgatttttac ggcttcagga ggcgcccgta tgcaagaggg
     9541 gatcatgagc cttatgcaaa tggccaaggt ctctgcagct gtgaaaagac attctaatgc
     9601 aggcctcttt tacctcacta ttttgacaga tccaactact ggtggggtaa cagctagttt
     9661 tgccatggaa ggggatatta ttttggcaga acctcaatcc ttggttggct ttgcaggtcg
     9721 tcgtgtcatt gagaccacag ttcgtgaaaa cttgccagat gatttccaaa aagcagaatt
     9781 tttacaagac catggttttg tggatgctat tgtgaaacga acagagttgc gagacaagat
     9841 tgcccactta gtagcatttc atggaggtgg ccaatgacag atgtatcaag aattttaaaa
     9901 gaagcgcgtg atcaagggcg tttaacaact ttggattacg ccaaccttat tttcgatgac
     9961 tttatggaac tgcatggcga tcgccatttt tcagatgatg gtgctattgt aggtggctta
    10021 gcttatttgg cgggacaacc tgttacggtc attggtattc aaaaaggtaa gaatttacag
    10081 gataatttgg caaggaattt tggccagccc aatccagaag gttatcgtaa agctttgcgc
    10141 cttatgaaac aggcagaaaa atttggacga ccagttgtta cgtttatcaa tactgcagga
    10201 gcctatccag gtgtcggtgc ggaagaacga ggacagggtg aggccattgc taaaaatttg
    10261 atggaaatga gtgatctcaa ggttcccatt atcgccatca ttattggtga aggaggctct
    10321 ggtggtgcat tagccttagc ggttgccgat caggtctgga tgctagaaaa caccatgtat
    10381 gcagtcctta gtccagaagg ctttgcttct attttatgga aagatggttc aagagcgaca
    10441 gaggctgctg aattgatgaa aattaccgca ggcgaattgt atcaaatggg catagtagac
    10501 cgtattattc cagaacatgg ttatttttca agtgaaatcg ttgacatcat caaagctaac
    10561 ctcatcgaac aaataaccag tttgcaagct aagccattag accaattatt agatgagcgt
    10621 taccaacgct ttcgtaaata ttaacaacat ccttttggag tctccctacg tgtttatcaa
    10681 gctaagggag gcctttccaa aagggttttt aactagtctt gtaaataagg aaatgggtat
    10741 actaataaga cttttgataa actagtgtga aaaaaagtgt tgttaaaggg gcaatgtagt
    10801 gagtttcaag tgatgtggtg gctctttaaa atagtaaacc ccagaaatca ctttaatgat
    10861 ctctggggtg agtttattat ttaggtgaaa tgacggtttc gccacccatg taagagcgga
    10921 gtacttcagg gatggtaaca gaaccatctt cattttggta gttttctaaa atggctgcta
    10981 cggtacgacc gacagcaagt cctgacccat taagggtgtg aagaagtttg accttaccgt
    11041 cagcttcatc acggtaacgg atttgagcac gtcgtgcttg gaaatcttca gtatttgaac
    11101 atgatgaaat ttcacggtag gtgttttgtg caggaatcca gacttcaagg tcataggttt
    11161 tagcagctga gaagcccatg tctccagtac aaagggaaat gacgcgatat ggcaaaccaa
    11221 gtttttgaag aatattttca gcattagcag tcattttttc tagttcttgg taagattctt
    11281 ctggtttagc aaatttaacc atttcaactt tgtggaattg gtgtaggcgg ataaggccac
    11341 gtgtgtcacg acccgcagaa cccgcttcag aacgaaaaga tgggctcatt gcagtaaagt
    11401 aaattggcaa ttctttgccg tctaggattt ccccacggta ataattggtc aaaggcactt
    11461 cagcagttgg aatcaggaca aagttggtat ctgctaattc aaaggtgtcc tctttgaact
    11521 ttggatattg tcctgtacca aacatggaat cgtggttaac catgtaaggt gtgatgattt
    11581 cttgataacc ttctttgata tgttcatcca gcatgaagtt ataaagagca cgctccaaac
    11641 gagcaccaag atttttatag aataagaaac gagcaccagt tacctttgcc ccacgttccc
    11701 agtctaaaat atcaagatct tcgcctagat cccaatgagc cttaacttcg aagtcaaagt
    11761 cacgaggcgt tccccaacgg cgaatttcga cattgtcttc ttcgtcagct ccaacaggga
    11821 cagaatcgtg aggagtatta ggtaaaacag tgatgatgtc agtaacttgc tggtcgatag
    11881 ctactagttg attgtcaata gttttgatat ctgcagagac tttttgcata tcagcaattt
    11941 gttgagtggc atcttctttt tgacgttttg cttgggcgat ggctgcagaa gcaatattac
    12001 gctctgcttt taattcttct gattgcacta atagagcacg acgtttttca tcaagttctt
    12061 taagatgggt cagggtgtct tcagaaacac cgcggttttt taatttggca gcgacagtgt
    12121 caaaatcggt acggatacgt ttaagatcta gcatacagaa gctcctttaa gatagttatt
    12181 agtagctgtc agtgaaacaa ggctaagtaa gacagttgga tcttgtgatt ctctgacgat
    12241 agaaaaagca cagcttatga agatgctgga gcgctttggc gcggttccat ccagcttcac
    12301 aatctgtgca cttaatctct attttattga tgacacggta gaatttcata tcattttccc
    12361 tatctgttca cagcatccac agactctctg aatgaaaaaa aggtattact tatccgttag
    12421 gactattata acaaaaaaca agaaaaagta aactcaaatg agggaatctt ttccactaaa
    12481 tagcaattta gagctactat tctttgcttt cttgaaatga taaatcagca ctgctcatta
    12541 tttttttaat gtcgaaaaaa tttgttaata aaggtttgca tcaaggttgg taatgtaatc
    12601 actttctcat taccaatatg ttgacgagtg atttttaaga tttttccaga gtctccagaa
    12661 gcaaataaaa acttgccttg gtccgtaaaa atttcaaagt ggcggctaac tttttttctt
    12721 gaaacattag ccccgatgtg attgatagct gtccaaggaa tttgaatata atcattcaca
    12781 tttttatcgt tgtaaaattc aagggccttg tcaccgagta aaatatgacc aactttgcct
    12841 cctattccaa ggtaggagac agcttttgtc ttgtattcga cactagtgtt taaagattga
    12901 gccatttaag ttcctttcat tgcgtagttg tagttattat accatatttt aagtgggatt
    12961 ttcctgacat aaagcataaa aaagaagcct gagttcatct cagacttcca ttggttgatt
    13021 acataatacc tgcaaggtga gcaaggatac caaatgcaaa caagccgatg atgattgcga
    13081 ttggagaaac ttttttcttc aataaccaca tgcaaaggaa tgtaaggagt aatccagcta
    13141 aacctgggat aagagagtcc aattgtcctt gaagggtttg agcttggact ttatcaaggc
    13201 tcataccgcc aatagcgttg gcaaggatag ttttcaactc agcaccttta acagcgccat
    13261 ctgggaagac cacataggca ccatctgaca attgttttcc aggaaggtcg atagtaaagt
    13321 tgatagatac ccaacgttga acaagcactg caaggataaa cattccaagg attgaagcac
    13381 ctttagtaat gtcttggagg ataccgcctg acatgtcttt agtaatttca gaaccagctt
    13441 tgtaaccaaa ttcttgagta taccataaga aggccatacg gataaggttc catccaaaga
    13501 agaacagaag tggaccaacg atgttacctg ttgaagccaa agaagcacca agtgccccaa
    13561 ggataggacg aaccgtaaac cagaatactg ggtcaccgat accagcaaga ggtcccatca
    13621 taccgatttt aaccccttgg atagccttgt catcaattgg cgtaccattt gcgcgttctt
    13681 cttcaagggc aagtgttaca ccaatgattg gagctgcaac gtatgggtga gtgttaaaga
    13741 attccatgtg gcgctcaaga gcagctgcac ggtcttcagg agacgtatac aattttttaa
    13801 gagcagggat aagtgcataa gcccagccca tgttttgcat acgttcgtag ttccaagaac
    13861 cttgtaagaa ttgtgaacgc caccaaacac gttgacggtc tgatttagtt aatttaattt
    13921 gttcagtcat ttgttcttac ccctttctag tagtcttcta agatgtcgcc gattggatca
    13981 gctgaacctg ctgcattacc accgttacca ccttttttag aaagattaag gtagatgaag
    14041 gcaattgcta caccgataac acccatagcg ataagggtta attggctgat agctgcaaga
    14101 gcaaaaccta gggcgaagaa tggccatact tcacgagtag ccatcatgtt gataaccata
    14161 gcataaccta cagcaacaac catcgcacca ccgatttgca taccttcgtt caaccagttt
    14221 ggcatagcat tcaaaacaga ttgtacggct gaagtaggaa cagcaacaag aagagctgct
    14281 gggacagcga tacgcaatcc ttgaagaaga agggcaataa agtggaagcg ttcaatacct
    14341 gcgaaattac cttcagtggc agctttgtca ccagcgtgta caagggcagt tgacaaagta
    14401 cgaacgatca ttgtaaggaa aagaccagca acagcaagtg ggatagctgt tgagtaagca
    14461 aaggtaattc ctttttgagt aaagtcgcca cttttgacca tgatgatagc agctgcaaca
    14521 gaggcaaggg cagcatcagg ggcaacggca gcaccgatgt ttgcccaacc aagagcaagc
    14581 atttgaagtg taccaccaag gatgacacca gcttcaaggt gtccagttac aagtccaatc
    14641 aaagtacagg caacaagtgg ttggtgcatt tgaaattggt cgaggatacc ttcaagacca
    14701 gcgaagaagg caatgataac gactaaaatt gcagaaataa tcgaaatatc tgacatgttg
    14761 taatcctttc aaagtatagt aaacgaggac tttttgctaa taagttagct agtcatcgtt
    14821 ttaaaacctt atagcgtttg aaacttattt aatgttagct ttttggataa gctcaaataa
    14881 gtttttctta gaatcgttag gaactttacg gacgtcgaat gtaacaccta ggtcgcgtaa
    14941 tttttcaaaa gtagcaacgt cttctttgtc cattgataaa acgttgttaa ccattgtttt
    15001 accagttgag tgagccattg aaccaacgtt caattcgttg atttcaacac caccttcaac
    15061 cgcgcgaagg gcatcttgag gggtttggaa aagaataagt gcgtgtgtgt taccaaaacg
    15121 aggatcttta gaagcttcaa tcaatttgct aattggaaca acgttagctt tgacaccacc
    15181 aggtgcagcc tgtttgatca attgtttgcg aaggtcatct tgagcaacct catcagaagc
    15241 aacaatgata cggtcagcct tagaagctgg agtccatgct gttgcaactt gaccgtgtaa
    15301 aagacgagtg tcaacacgag caagattgat ctttaattta ccatctccga tgacagttcc
    15361 agcaggaata gctccttgaa gtgcgttaac aactttttca gttgcagcag tttcttcaac
    15421 tgggttaagg tcttcaggaa gggctttgat accgtcctta gattccttaa tgatgtttgc
    15481 agcaacttgt tcaacacctg caccagcatc cataagacgt tcagtgtaag cttgaataag
    15541 cataggcaag ttgagaccag tgatgatcgc cattttgcgg tcaggatttt cacctgccac
    15601 acgactagct tggttaaatg gagaaccact ccaaaggtca gctagcacaa ggatttcatc
    15661 atcagcatca aattgttgga tagcattgtt gaagtgtcca tacaaatcat ctggtccttc
    15721 gtttggcatg aaagtaacaa cttgaacttt ctcttgttca ccaaaaatca tagaaccaga
    15781 ttgatgaata ccttcagcaa atttaccatg gctggcaata ataataccga tacccattct
    15841 tgttcttcct cctttaaaat atttttcgtt gaaatgaaga agaataatct ccttccaaaa
    15901 ctaaattttg gcaattcttt ttcacttaaa cgaaattcaa gaacgtttct attttaaaac
    15961 gttttcacta aaaaatcaag ccctttcgga aaaatagtac aaaacatgaa aaaattttca
    16021 gaatttagg
//
LOCUS       DATWVB010000035        15608 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.035, whole genome shotgun sequence.
ACCESSION   DATWVB010000035 DATWVB010000000
VERSION     DATWVB010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15608
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.035"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(102..2093)
                     /gene="uvrB"
                     /locus_tag="VCX65_001352"
     CDS             complement(102..2093)
                     /gene="uvrB"
                     /locus_tag="VCX65_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEP5053812.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIIYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
     gene            2285..4459
                     /locus_tag="VCX65_001353"
     CDS             2285..4459
                     /locus_tag="VCX65_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEP5053813.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPIKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATITDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDIVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            4459..5199
                     /locus_tag="VCX65_001354"
     CDS             4459..5199
                     /locus_tag="VCX65_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP5053814.1"
                     /translation="MTELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVVVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEAAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(5347..5499)
                     /locus_tag="VCX65_001355"
     CDS             complement(5347..5499)
                     /locus_tag="VCX65_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053815.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
     gene            complement(5496..6875)
                     /locus_tag="VCX65_001356"
     CDS             complement(5496..6875)
                     /locus_tag="VCX65_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEP5053816.1"
                     /translation="MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGASSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     TAIFIFSKREEHKTIAKLSAPMGIFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
                     NKEKASDLA"
     gene            complement(7053..7502)
                     /locus_tag="VCX65_001357"
     CDS             complement(7053..7502)
                     /locus_tag="VCX65_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEP5053817.1"
                     /translation="MIISAEGDVSVHHCFEAMLISLQEDYRQNTLRQLSRDDIKAGIN
                     YVKHYGKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYRLEALGENRTRITYSYD
                     YHPLDIFQKANYFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            complement(7499..7834)
                     /locus_tag="VCX65_001358"
     CDS             complement(7499..7834)
                     /locus_tag="VCX65_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEP5053818.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            complement(7837..8148)
                     /locus_tag="VCX65_001359"
     CDS             complement(7837..8148)
                     /locus_tag="VCX65_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP5053819.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EVAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            complement(8171..10165)
                     /locus_tag="VCX65_001360"
     CDS             complement(8171..10165)
                     /locus_tag="VCX65_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEP5053820.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVM
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LAKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            complement(10271..11365)
                     /locus_tag="VCX65_001361"
     CDS             complement(10271..11365)
                     /locus_tag="VCX65_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEP5053821.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAEQSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFITAQSASEGPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEKIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVREDYLSLLDDLRPWQEFCLEIDPS"
     gene            complement(11374..12774)
                     /locus_tag="VCX65_001362"
     CDS             complement(11374..12774)
                     /locus_tag="VCX65_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEP5053822.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSDAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEVIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            12999..13694
                     /locus_tag="VCX65_001363"
     CDS             12999..13694
                     /locus_tag="VCX65_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEP5053823.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILVTLIFYGILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVVICFATFLINDSYTFYSWL
                     MLQRYQEKKVKKG"
     gene            complement(13699..13857)
                     /locus_tag="VCX65_001364"
     CDS             complement(13699..13857)
                     /locus_tag="VCX65_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053824.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(13926..15239)
                     /gene="obgE"
                     /locus_tag="VCX65_001365"
     CDS             complement(13926..15239)
                     /gene="obgE"
                     /locus_tag="VCX65_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEP5053825.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVNEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATA
                     ELLAKTDEFLLYDESDLVDEEAYYGFAEAEKEFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD"
     gene            complement(15296..15424)
                     /locus_tag="VCX65_001366"
     CDS             complement(15296..15424)
                     /locus_tag="VCX65_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEP5053826.1"
                     /translation="MAFGENGPRKKTTFEKVTMVVVILMVLVTVGGLIASALSVLM"
BASE COUNT         4701 a         3333 c         2796 g         4778 t
ORIGIN      
        1 tctttacttt aaaaagttaa cttaaaattg tcctaataaa aagaattatt tgactttaac
       61 ttatatatgt taataagtat aatataagct ttattcaaaa cctagtccat taatttaagt
      121 tctaaaatca agtctcgcat ttgagctgcc aattcgaaat caagtaattc agctgcctct
      181 tgcatttgtt tttgcagagc attgatcgct tcttttcgtt ctcctcttga catactttca
      241 taatccatct cttctttcga tatatcattg tggcttgttt tacttatact aataaggcct
      301 ctgatgtctt tttttatagt ttgtggaacg atgccgtgcg ctttgttata tgctatttga
      361 atctcacgac gacgagccgt ttcgtcaata gcccgctgca tagaatctgt catcttgtcc
      421 gcatacataa tgacatgacc atctacgttt cgagctgctc taccgatggt ctgaatcaag
      481 ccgcgttcat tacggaggaa accctcttta tcagcatcca aaatggctac aagactaact
      541 tctggcacat caatcccttc acggagcaga ttgattccaa tcaagacatc aaaaacacca
      601 agtcgtaaat cacgaataat ttctgtccgc tctaaggttt taatatcact gtgcatatac
      661 ttgaccttga cacccatctc ttttagataa tcagtcaaat cttctgccat ttttttagtt
      721 aaggttgtga tgaacgtccg ttcatcgcgc gctacgcgct ggttaatttc tcccaacaaa
      781 tcatccattt gccccatact tggccttaca tcaatttcag gatcaagtag cccagtcgga
      841 cgaataattt gctcaataat tgtattagtc tgtgacattt cgtattcacc aggcgttgct
      901 gaaacataga taatttggtg cacatgactt tcaaattcct cgcgtcttaa gggacgatta
      961 tcaagagctg atggcaatcg aaaaccatag tcaactagca tttgttttct ggcttggtca
     1021 ccattataca tgcctttgat ttgtcccatt gtcatgtgac tttcatcaat cataattaaa
     1081 aaatcttctg ggaagaaatc taacaaggta taaggaggtt ctcctggtga cctgccatcc
     1141 atatgacggg aatagttttc gactccgcta gtatagccca tttcacgtaa catttcaata
     1201 tcatattccg ttctttggcg taatcgctgt gcttctagta gtttaccttc agattcaaat
     1261 aactgtaact gctctgctaa ctctgcttga attttggcta ttgattgctc catatgctca
     1321 tcatttgtta caaagtgagt agctggaaat aaaaccaaat ggtcaacttc tccaatagtt
     1381 ttcccagtta aactttcgat ttcacatata cgatcaatct catccccgaa aaattccacc
     1441 cgaaaagcat gttcatccct ggatgctgga aagacctcaa caacatcgcc acgtacacga
     1501 aaacagccgc gttgaaaatc aatatcatta cgctcaaatt gaatatctac taattgattt
     1561 agcaaagtgt cacgtgatat ctcctgacct ggacgtaggc tgactgctga atctgcgtac
     1621 tcttttggcg aacctagtcc ataaatacaa gatacagaag ctaccactat gacatcgtta
     1681 cgctcaagta aagaagaggt ggctgaatgg cgaagtttat cgatttcatc attgactgaa
     1741 ctatcttttt cgatataggt gtcgcttgat gggacatatg cttcaggttg gtagtaatca
     1801 taataggaaa caaagtattc cacagcattg tctggaaaaa attctttaaa ttcaccatat
     1861 aattgtcctg ctaaggtttt attgtgagct atcactaagg taggtttatt tactttacta
     1921 attacttggc tcatggtgta tgtttttccc gttcctgtag cacctaggag aatctgagct
     1981 ttttctccgc cctcaatatt atcaactagg ctttcaatag cttgtggctg atcaccagac
     2041 ggtttatact ttgattttag tttaaatggt ttatcatcac gtttatcaat cattttatac
     2101 cctctaatag tcttatctct tatagactat tttaacatag ataagccaga atcacctcca
     2161 ataagcgtaa aaaacatgtc atttacatgt tatgttttat gacatataaa taacaaattt
     2221 cttgcttaat gttcaacatt ttgttataat taaccatatt ttttagtttt ataaggagat
     2281 tagtatgacg cacaaaataa aagtattgct gcttgcgata atgtctattt ttttgacatg
     2341 caatattgca agtgctgaaa ctattgctat tgtttcagat acagcttatg ccccatttga
     2401 atttaaagac tcagatcaaa tttacaaagg aattgacgtt gatattatta atgaagtagc
     2461 caaacgtcaa tcttgggatt tcagtatgag tttcccgggt tttgatgcag ctgtaaatgc
     2521 tgtacaatct ggtcaagcga gtgctctaat ggccggtaca accattacga atgctcgtaa
     2581 gaaagtcttt catttctcag agccatatta cgataccaaa attgtcattg cgacacgtaa
     2641 agccaatgcc atcaaaaaat acagtgactt aaaaggaaaa acggtcggtg ttaaaaatgg
     2701 aacagcggct caagcctttt tgaataacta taaaaaaaag tatgattata ctgttaaaac
     2761 atttgacaca ggtgatctta tgtataatag tttatctgct ggttctattg ccgctgttat
     2821 ggatgatgaa gcggttatcc aatacgcaat cagccaaaac caagatattg ctattaacat
     2881 gaaaggagag cccattggaa gctttgggtt tgctgtcaaa aagggaagcg gatatgatta
     2941 tctagttaat gatttcaata cagctcttaa agctatgaaa gctgatggta cctaccaagc
     3001 tatcatgacc aagtggttag gcacagatga taaagctacc accagtcagg caacgggaaa
     3061 tccatctgcc aaagctacac ctataaagga cagttataaa attgtctctg attcgtcttt
     3121 tgcacctttt gaatttcaaa atggtaaggg caaatacgtt ggtattgaca tagaattaat
     3181 caaagctatt gctaaacaac aaggtttcaa aattgaaatc gctaatccag gtttcgatgc
     3241 tgccttaaat gctgtgcaat ctagccaagc agatggggtc attgctggtg caactattac
     3301 tgacgctcgt aaagctatct ttgatttttc tgatccttat tatacttcta atatcatttt
     3361 agctgttaaa gctggaaaaa acatcaagaa ctatgaagac ttagacagaa aaacagtcgg
     3421 tgctaaaaac ggcacttcat cttactcttg gttaaaagaa aacgctccta aatatggtta
     3481 taatgtcaag gcatttgatg atggttctag catgtatgat agcttaaatt caggttctgt
     3541 agatgctatc atggatgatg aggcggttct taaatacgct atttctcaag gtcgtcgctt
     3601 tgaaacacct cttgagggca tttctactgg tgaagttggt tttgctgtca agaaaggaac
     3661 taatccagaa ttaatcgaaa tgttcaacaa tggcttagct gctctcaaaa aatctggtca
     3721 gtatgatgac attatagata aataccttga ctctaagaaa gctgcaactc cttctgaaaa
     3781 aggtgctgat gagtctacta tttcaggcct attatcaaat aactacaaac aactattggc
     3841 aggacttgga accacgctca gtttaaccct tatttcattt gctattgcta taattatcgg
     3901 gatcatcttt gggatgatgg ccgtgtcacc aactaaatca cttcgactca tttcaacggt
     3961 ctttgtagac attgttcgag ggattccttt gatgattgtg gctgccttca ttttctgggg
     4021 agtaccaaac cttatcgaga gtatgaccgg ccaccagtca ccgattaatg atttcttagc
     4081 tgctacaatt gcactgtcac ttaatggcgg agcctatatt gctgaaattg ttcgcggtgg
     4141 tatcgaagct gttccagcag ggcaaatgga agctagtcga agtcttggtt tgtcttacgg
     4201 aaccacgatg agaaaagtaa ttctcccaca agctgtgaaa ctaatgttac ctaactttat
     4261 caatcagttt gttatttcat tgaaggatac aacaatcgtc tcagcaattg gtttagtgga
     4321 actcttccaa acaggtaaaa tcattattgc tagaaattac cagtcgttcc gtatgtatgc
     4381 tattttagca attatttacc ttatcatgat tacactctta acaagacttg caaaacgttt
     4441 agaaaagagg cttaactaat gacagaatta aaaattgatg ttcaagattt acacaaatct
     4501 tatggtcaaa atgaagtctt aaaaggaatt gatgccaaat tctacgaagg tgatgtcgtt
     4561 tgtatcattg gtccttctgg ttctgggaaa tcaacctttc tacgtaccct caaccttcta
     4621 gagacgatta ccagtggtaa ggtcgtggtg gacggttttg aattatcaga tcctaagact
     4681 aatattgaca aggcacgtga aaatatcggg atggtattcc aacacttcaa ccttttccct
     4741 cacatgactg ttcttgagaa tattatcttt gctcctgttg aattaggtaa agagtctaaa
     4801 gaagctgcta aaaagcacgg catggcactt ctagaaaaag tcggactttc tgataaggcc
     4861 gacgccttcc caggaagttt atccggcggg caaaaacagc gtgtcgccat cgccagaagt
     4921 ttagcaatga acccagatat tatgctcttt gatgaaccaa cttctgctct tgaccccgaa
     4981 atggttgggg acgttttgaa cgttatgaaa gacttggcag aacaaggcat gaccatgttg
     5041 attgttactc acgaaatggg gtttgctcgt caagtagcta accgcgttat ctttacagat
     5101 ggtggtcaat ttttggaaga tggaactcct gaagaaattt ttgaccatcc taagcaccct
     5161 cgtctcattg aatttttaga caaggtctta aacgtctaat agagcagaca ccatactaac
     5221 ttccaaaaaa taataaggca aggaaacagg tttccttgcc ttttttggtt actgttatta
     5281 ttcaaaccag caaaataggg atactcttat gactctctac ttcataagag tgtcccctat
     5341 gcttttttat gggcgtttat gtttagtgag gtaataacct aatcccgtaa gagctagtcc
     5401 cgtcactatg tgtaagtatt tgttaccaac catcggacta atggcaatga gaaaaaagcc
     5461 aacagccatt aaaaaagttg ctccattttt ttctgtcatg caaggtcact cgctttttct
     5521 ttattggcca aaatgacaaa tggtgcccag ataaggaagg caacaaagag gttaaacagt
     5581 gaaaccaaac ctgccataat attacctcca gtagctaggt aagcataaag tccaacaggg
     5641 gtaatccaag gtactgataa gaataccggt ggaatcaaac ctattgcagt agcaaaataa
     5701 gctatgctag cacaaattgg tggcacaatt agccatggaa tcacaaaggt tggattcaaa
     5761 acaattggca tcccaaatgt aattggttcg ttgatattga aaatacccat tggtgcggac
     5821 aatttggcaa tggttttatg ctcttctcgt tttgagaata tgaagatagc agtaatcaat
     5881 gccaaggtta ctcctgaacc acccatttga gcataagcat caaaggaccc gcgtgtccaa
     5941 aggtatggta aattagcagc gctatgcgct gtattgtaag cagctgtatt ttctgttaaa
     6001 gctaccatat aaataccatc catcactggg gctaagacat tatgaccatg caagccgaag
     6061 aaccagagca gttgaactaa gaaggttaac aagataactg aaccaatacc ctgtgataag
     6121 cctagcaatg gtaattggat ataggttgaa atgacatcac ttagggaaga acctgttaat
     6181 gcgaagatga ggtaggcgaa aattgccgaa gcgtaaatcg caactgttcc tggaataatg
     6241 gcagcaaagg ctttattaac cgcaggtggt acattatctg gtaaggtaat ggtaatatta
     6301 cgtttggtca aagccgcata cacaaaactt gataaaaagc caataattaa agctgtgaac
     6361 aagcctgtgg caccgacata ctttagagct attgctcccc attgactagt ttcaatactt
     6421 gaagctccac ccgcagtaac gactgaaagc cccatttctt tcaaattgct aattaggtta
     6481 gcagaggcat tttcaagtgg tgtcgaaatg gttaaagtct gaggtagggt ggcaataaat
     6541 gagccaaaag aaatcaatcc tcccgccaat ggattaatct tatgcataac agctaaattg
     6601 taaccgaaag caaaggcaaa aaagagcgcc atgataccaa ttgtcccaaa ataaacatag
     6661 ccattgatgt cgataacagg ttgcatagct tttgcaaacc ctgtccatcc catattgttt
     6721 ggaatatcgc gtaaaaaaac gttcaataag acagcaactg aacctgccat ggtaataggc
     6781 atcattgaaa taaaggaatc acgaatagct actaaatgcc gttgtgaccc aatttttcct
     6841 gaaatctcca taaacttatc agaaaaatgc gacataaatc ttctcctctt tttatttttt
     6901 taatgtaaca aaggtaacct taaaagcagc ggtgtctgcc taacacaatt atctcaaaat
     6961 catccttgtt aaacgtgatg cttaaagata accggtaatc ggctcttatc caaatgaacc
     7021 cttctctctc attcaaggtc tatgaataat cttcacaaag acgatggttg ctgcaactgt
     7081 ttagcatatt ggataagggc tgctaactgg gcttgagatt ggcgttctag gctttttttg
     7141 aacagtttgc caacaataaa ataatttgct ttttgaaaaa tatctagagg atgatagtca
     7201 taagaatagg taattctagt ccgattctcc cccagagcct ctaatcgata agccaattcc
     7261 tttatcccat gattggaact aaaacaagca gtatataatt gcggagcttc tagggccgta
     7321 ataagcaccc tcactgtacg ctctttgtat ttaccataat gtttaacata gtttatcccc
     7381 gctttgatat catctcttga caactgtctc aaggtatttt gtcgataatc ttcttggagc
     7441 gatatcagca tggcttcaaa acaatgatgg acggaaacat ctccttctgc tgaaatgatc
     7501 atgactcacc tctttgtatt gctgacattt tgtcgtaaac ggtaaccaat tccttggcta
     7561 aatcaataaa ggctaaggca gtcatcatgt gatcttgccc atgcaccatc aataaagaca
     7621 attcaaccgc atcaccagct gcttcttggg acagcaaatg tgtctgcgat ttatgggcaa
     7681 tatttaacga gtttgtcgct tcttgaagta agtgctgagc ctcctcaaac tgcccatctc
     7741 gtgctgcatg aatagcctct acggccttgc ccttggcttc gcctccatac atgattaagc
     7801 ccataatagc ttctaagttg gatggttccg tcatgcctac tcctccatca tcgctagggc
     7861 tgtttcaagg actttttcac cgttcataag accataatca gccatgttaa tggcatctac
     7921 tttaatatct ggttcaaact tatctttaaa atcctttagt aagaatttga cttgtggacc
     7981 taacaagaga acgtcaatgc tattagcagc cacttcgttg tcagcttcac tcacaggaac
     8041 tgcccaaata gaaacttcaa ggtcacgcgc ttgggctgct ttttgcatct tagtcaccaa
     8101 catactagtt gacataccgg cattacaaac taacataata gatttcataa ggtttctcct
     8161 tttaatcgtt ttaatcatga ataagtgggg taaacactgt catgaatttg gaataatttg
     8221 gttcttctag taacgcttgc tgaagctcca cctgattgac aaaagatgcc aaacctggtg
     8281 atacatattt taacctatga ttatgccctt tagacgggga taatagaaag acaaaatgaa
     8341 cagcttgatg cgccttgtcc cactcaagag gctctcggca aatagccact actacctgtt
     8401 cagaataagt catgggatta gcaggatgcg gaaaggcaag cacttctcca tagatgactg
     8461 ggctgtaatt ttccctcagt accatttgat gataaaagtc ctctacaaac gtttctgttc
     8521 ccgcctcgtc aagacaagca atcatccgta aaagcaagtc ttcctttgag attttctcgt
     8581 ctaaataaag aaaacgatta gggctaaaaa cacctgttag aagctgctct gcttttgcta
     8641 aactcatctg tgacggtaaa ctgacctctt tcttgatacc ttcttgttct ccaataaatt
     8701 gtcgaatagt ttcaatatcc tgatttgaca aaaaaacact gacagtaatc actggtgtta
     8761 aaaacatcag attggcaagg ctgatagagg aaataatcaa atcaacggtt ttcagtcgct
     8821 cttcggttat ttcatagtaa ctgataacat cgacaatacg caaacgtcct tcaaattcct
     8881 tttccaagcg atttttcaac atcatggcac taccataacc tgtggcacaa actactagaa
     8941 ccctcaattt atgacggttt gaataacgct caatggccgc cattaaatgc aaactaatat
     9001 aagcccattc atcatctgag acatcattct tttgacatac aagcaaatcc gaaaaggtct
     9061 gcttggtaag ggtaaatatt tcaggatact ggcttttaat ttcctcagtt aaaggattag
     9121 tcagctgaat atggttttca agacgtgtgg tcaagggcat catgtgggct aataaacctt
     9181 gaaataaatt ggtatctgtt tctaaagtca tgcctgtcaa ttgactaatc ttggcaatac
     9241 atgcttttaa atggtcctgc aacttttcat cggtattatc atcttgccaa tgcttaccaa
     9301 cagaatgttt gacctttaga tgcagtgcaa tataattagc ctcctcttta ggaaaacgta
     9361 tccccatcac ttcttccact cgatacaaaa tgcgcagagc tacttgatac tcatcagact
     9421 gacgaatagc tattggaatg gaaaacagtt ctaatggaca ccccgatcga atacgctgaa
     9481 ccattagggc aatatgcaag actagattat tcatgacaaa atcagaaagt ttcaacttag
     9541 catcccgaca ttcatccaag acaataatca tgatttctgc aaaattaata ccttcaagaa
     9601 aggtattacc taccatggtg gacaaggtgt tatcaaaact agtaacaaaa aaataatcca
     9661 tgataaaatg cctaatgtcc tcttctttac ctcttatttg aatatgttgg tgagttattt
     9721 caagctctaa ctggtaaggt attatgcgct ccttaatgcc tgctaaaaca tgttttaaag
     9781 ttgtccgact gatatacaat tcttgacaaa gctcttcaaa atcctgaacg gcatcttcaa
     9841 aaaagaattt atgaagcaca taatcttctc gatcaaccga ttcttccact tgagtcacat
     9901 ctgctaaacg ttttttagac gtcacacttt cttgccaaaa gatgtcaaat gccatagagt
     9961 ggtcaatttc taagcagtaa cctcgacctt gtttagaaat gatgtgagct ccgtgttcag
    10021 gaaggctact gatcagttct ttgaggtatt tcctaaccgt acggtcactc ataccaataa
    10081 cctcagccag agttgcacta gagacaaact gctctttgtg atggattaga aatgttatga
    10141 tggccagttc tttttttgat aacattagtc ctccttacta ctttagaaaa cgctctctac
    10201 cctcttttag tgtaccaaat atttcctgaa aaaggtgacc atcattttcc gcattgattg
    10261 tgaaaagaat ctatgatggg tcaatctcca aacaaaattc ctgccaaggt cgcaaatcat
    10321 ctaacaaact aagatagtcc tctctgacct cagcaaccac attagctttt gaactaaccg
    10381 taaaattttt caaagcaatt tgcagttctc ccttatatcg atgatagcgg tcattgtcaa
    10441 taataatgct acctcgtttg acctccttag attggtctct tggagcaatc gattcctgag
    10501 cataaactag acgtggcatg gttgatcgaa tcacataatc agatacatcg ccacgataac
    10561 aatgcggata gccaatgatt ttctcctcaa cttctgtcaa atcgatgata ggcctaacct
    10621 tgatcgttgt gactggtctt gctaaagcct gagtacatgc tgccaattct tcttccgaaa
    10681 tgaattggtt agatatgagg atattatcaa tggttcctat cgctttcatt aattctactt
    10741 gcaggccaat gggcaagtgc ctatggtctt ccactgtcgg caagccttct gccagtagcc
    10801 aagggccttc agatgctgac tgagcggtaa taaaagcagc cgtttcaata tcatgctcat
    10861 gataaaaacg tgacatatcc ttaaaatgtt gccatgacaa accggtaaat tcatgtggat
    10921 aaaaattatg gcaaccaata atattgctct gttctgcatc tgtcgctagc aatgacatca
    10981 ataattgttt atcagtgctc atattaagtt caattttaag cccaaaggga tttcttgtta
    11041 aagttacaat ctctgctaga gggagagcct cgtctaagcg taagcccgct aacccgaagg
    11101 catgagctcg ttcaataagc tgatctgacc aaccagcttg gctaataaag cttggactaa
    11161 cgtcagcaat tactcgaatg cctaattgat ttgcataagc aatgagctct gcgtagcaat
    11221 gaaacatctg gtgatcagct ggtgccagct gtaagagact cataaacaag cgcttggctc
    11281 catagctatg acataagtca atataagctt tactcttggt aacatcatac cgctcagggt
    11341 atagagaaaa tcctaaatca accatattgc ctcctattta tcaaaaccat ttgactcgct
    11401 caacgcctta aaccagtaac ctgatttttt tatggttcgc ttttgactct ctaaatccaa
    11461 agctaccaaa ccatatcggt ttttataagc atttaaccaa gaccagcaat caataaaagt
    11521 ccacaagagg tagcctttgc agttggctcc ttctcccaaa gccttatgaa gctggataag
    11581 atgatcctcg ataaaggtga tgcggtagtc atcttgtatc tggccatctg ctaaaaaagc
    11641 ttcttcacct tcgacaccca taccattttc cgtgactagc cattcgatgt taccatagtg
    11701 ttcttttaaa ttaagggcaa tatcataaag tcctggttca taaatttccc aaccccggtg
    11761 aggattgact tttttaccag gcatatcata aggttcaaaa taaatatcta agataagggg
    11821 gtccccctct tgctgtgact tactaggtgc ctgaacccgc aaaggctgat aataattaac
    11881 tcccaaaaaa tcaacagtat tgtttttgat aacctctaat tcatcagcac tatattgagg
    11941 taataaatca gcttcctcta aaatggaaac taactctgct gggtaaacac ccaaaactga
    12001 tggatctagg aaggatttgg tttggaaaag ctctgcgatt ctagcagcct tgacatcttc
    12061 aggagcatca ctccgaggat aagcaggtgt catgttaagc acaatactaa tcttgtggtc
    12121 gggatgaagc ttatgacaag ctttaaccgc cagtgaactg gccagttgtg tgttgtaagc
    12181 cacttgaact gctgccttgg catctacttt acaagggtag tgataataac ctaaatagcc
    12241 acattcgact ggaacaatcg gttcattaaa ggtaatccaa gtgtttacta aatcaccaaa
    12301 aagctcaaaa caggtttttg cgtaggtttc ataagcccaa acagtagctt tgttttccca
    12361 gccacctttt tcttgcaagg cataggggag gtcaaaatga tagaggttaa caatcaattt
    12421 aataccttga gcaataatgt cttgaaatac ttctcggtaa aatgtcaccg cctttggatt
    12481 aacctccccg actccttctg gaatcaatcg agaccactgg attgaggtcc gaaaaatcgt
    12541 gtggcctgtt tctttcaaaa gggcaatgtc acccttatag ttttcataaa aggttgaggt
    12601 tttttctgga ccaatttggt gatgaaactt agctgactca atactaaacc agtaatccca
    12661 gttgctaggt cctttgccat ctccaggaac cgttccttcg ctttgaggcc cagatgtgga
    12721 acttccccat aaaaagccat ctggaaattg ataacggtgt tttctttgtt tcatatcctt
    12781 tgtcctttct ttgctcactt ctctttttat tataagaaga aaaacaggtg atgtaaacgc
    12841 tttaaaaaat ctgttttttc cttatcatca cggaaaataa gtgatttaaa gcttgacata
    12901 ttttattatc ttaaagagcc tatctaacct gccctgctac ttcttatcaa aaccaagccc
    12961 ctattgacag atgccttagc ctatgtttga ataggggtat ggcttattta aactacttta
    13021 caaaaaccga gtgggcactt tggttaagct ctgtcttggc cattttaatt agcgcccttt
    13081 tattcggtaa gcaagctccc ttagctttaa tagcttcttt gattggtgtg acctctctca
    13141 tttttagtgc taaagctaat cctattggtc aagggctcgt cattattttt tccattatct
    13201 atgcctatct ttcattacga aacagttact atggagagtt aatgacctat cttttcatga
    13261 ccctccctat gactattttt tcacttttta cttggttaaa ccatcctttt gaagggaaaa
    13321 aatcacaagt gactatttca cgattaacac ccactgatcg aagatgtctt ttcgttttta
    13381 ctatactggt cactcttatt ttctacggca tcttggcttc tattcaaaca gcctatttac
    13441 ttgtctccac tttatcgatt gccacttctt tctcagccgt ttatctcagc tataagcgaa
    13501 gcccttattt tgctttggct tatggactca atgatctagt cctcattctc ttatggatgc
    13561 atgctgctca aacagatgcc agccaatatg ctgtggtcat ctgctttgcc acctttctta
    13621 ttaatgatag ttacactttt tatagttggc taatgctcca acgttaccaa gaaaaaaagg
    13681 tcaaaaaagg atgagggcct aagcctcatc ctttttcaat ttttcacgtt ctaagcgcaa
    13741 acgtctattg ggatttaaaa gattaaacaa ttcttctaat ttctcagcat tccaaacatc
    13801 tgctgccgat acaaaatttc catccttatc cttaaaggat atcggtttat cacccataat
    13861 cagaaacctc catcttaaag ataaaacaca aggctgctat ggcaatgcca tttctaaaga
    13921 ccacattaat ccacaaattc aaattcaaat ttgccaatac gaacaagatc cccgtctttt
    13981 gctccacgtt cacgaagggc ttcgtcaacc cccataccgc gcaattgacg ggcaaatttc
    14041 atgatggatt cgtcacgttc catattggtc atgacaaaga gacgttctaa cttctcacca
    14101 gacaagaccc aagtagcgtc atcgtcacgt gtgatctcaa attctttctc agcctcagca
    14161 aaaccatagt aagcttcctc gtccaccaga tcagattcat catacaataa gaattcatcc
    14221 gtcttagcaa gtaattctgc cgttgcttct aacaagttct ctaagccttg atgtgctagg
    14281 cttgaaatag ggaaaatcat tggcaaatca tcaaactcgt catattgggc agccaatttt
    14341 ttcttgaagg ctttcaagtt ttcttgagcc tctggcatgt ccattttatt agccacaata
    14401 atctgtgggc gctccatcaa tcgcaaatta taggtttcca gctcgttatt aatagaaaca
    14461 taatcttcgt aaggatcacg accctcacta gcagacatgt caatcacatg aagaataacc
    14521 cgtgtccgct cgatatgacg gaggaattga gttcccaaac caaccccttg gctagcacct
    14581 tcaatcaaac ctggcagatc tgccatagca aagctatcac ctgactttgt acgaaccatt
    14641 ccaagattag gaacaatagt ggtaaaatga taggcaccaa ttttcggttt agctgatgac
    14701 acaacactta acaaggttga tttcccaaca gatgggaatc cgaccaagcc aacgtcagct
    14761 aagattttga gttctaactc taactgacgt tcctcacctg gctcaccatt ttcagcaatc
    14821 tctggcgcag gattacgagg agttgcaaaa cggatattcc cacggccacc acgaccaccc
    14881 ttagcaatga ccacttcttg accatgttct actaagtctg taattacttt tccagtttca
    14941 gcatcacgaa ccgttgtccc ttgaggaaca aaaacaatca aatcttctgc accacggccg
    15001 tgcatgcctt tggtcatacc tttttcacca gatttcgcct tgaatttacg attatagcgg
    15061 aaatccatca aggtacgcaa accttcgttc actcggaaga taactgagcc acctttaccg
    15121 ccgtctcctc cccaaggacc gccatttggg acgtactttt cacgacgaaa agctaccata
    15181 ccatcgccac cacggcctgc ttggacactg atttttgccg tatctaaaaa catactcata
    15241 ctttttttat tctctaactt tcttttactt taaaaaaacg cctttcagcg tttccttaca
    15301 ttaatactga tagggcactc gcaataagcc cgccaacagt tacaagaacc attaggataa
    15361 caacgaccat tgtcactttt tcaaaggttg tttttttgcg aggtccattt tctccaaatg
    15421 ccacgttaaa tacctcatct attgattttt cttcttatat cttaacatga aagatcgttt
    15481 taggcaaata ccagatgaat atttacgcta tgtaggctat tactgagtat tgtatcttgt
    15541 gaatttcata tgaatatgat acattagcat ttgcaaaata atgttacaga taaaaacctc
    15601 ctcgtctg
//
LOCUS       DATWVB010000036        15347 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.036, whole genome shotgun sequence.
ACCESSION   DATWVB010000036 DATWVB010000000
VERSION     DATWVB010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15347
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.036"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            85..333
                     /locus_tag="VCX65_001367"
     CDS             85..333
                     /locus_tag="VCX65_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEP5053827.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN"
     gene            370..981
                     /gene="amaP"
                     /locus_tag="VCX65_001368"
     CDS             370..981
                     /gene="amaP"
                     /locus_tag="VCX65_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEP5053828.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFKIIVKGRLASRVAVADQIS
                     GVKEGIEKGLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            992..1180
                     /locus_tag="VCX65_001369"
     CDS             992..1180
                     /locus_tag="VCX65_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEP5053829.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1193..1732
                     /locus_tag="VCX65_001370"
     CDS             1193..1732
                     /locus_tag="VCX65_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP5053830.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1773..1973
                     /locus_tag="VCX65_001371"
     CDS             1773..1973
                     /locus_tag="VCX65_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEP5053831.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKVK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            1984..2472
                     /locus_tag="VCX65_001372"
     CDS             1984..2472
                     /locus_tag="VCX65_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP5053832.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTNAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            2635..3276
                     /locus_tag="VCX65_001373"
     CDS             2635..3276
                     /locus_tag="VCX65_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP5053833.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICSQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(3419..3961)
                     /locus_tag="VCX65_001374"
     CDS             complement(3419..3961)
                     /locus_tag="VCX65_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP5053834.1"
                     /translation="MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            4079..4780
                     /locus_tag="VCX65_001375"
     CDS             4079..4780
                     /locus_tag="VCX65_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053835.1"
                     /translation="MAFIELKQVSKSYQVGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            4795..7431
                     /locus_tag="VCX65_001376"
     CDS             4795..7431
                     /locus_tag="VCX65_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEP5053836.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWSKRETDLVLSSSLAKNYQIGDELAVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSNLRLTNAFS
                     KDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRVALAKETVKLAASEENL
                     TFLEGSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSATSLSPYFNLLDS
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSNTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNANHIKSVQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            7523..8119
                     /locus_tag="VCX65_001377"
     CDS             7523..8119
                     /locus_tag="VCX65_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEP5053837.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLVNL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDAADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            8130..9086
                     /locus_tag="VCX65_001378"
     CDS             8130..9086
                     /locus_tag="VCX65_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEP5053838.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            9183..10523
                     /locus_tag="VCX65_001379"
     CDS             9183..10523
                     /locus_tag="VCX65_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEP5053839.1"
                     /translation="MNEIKCPHCHTLFTINESEYSQLLEQVRGQAFDEELQKRLINEM
                     ALLEEKAKHQLHEVVAKKETAITSLTNQLEQIEKEQAYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVVSLTNQLDKLALEKDATFQSKLATIEKERDGIKNQL
                     ALQAKESELSLASVRSDYEAQLKAANERVEFYKNFKAQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFVKDNQLSSRGSKGDYIYREVDANGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKDCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAALNSLHYKQELALIKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVRRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFAALKDQ"
     gene            10639..11523
                     /gene="truB"
                     /locus_tag="VCX65_001380"
     CDS             10639..11523
                     /gene="truB"
                     /locus_tag="VCX65_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEP5053840.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARTGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACSKGTYVRTLAVDLGRALWVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            11552..12484
                     /locus_tag="VCX65_001381"
     CDS             11552..12484
                     /locus_tag="VCX65_001381"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEP5053841.1"
                     /translation="MEIEYIKDYRDINQEDDTVLVLGYFDGLHRGHKALFEKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNCTDSDYLTRNFEGQVYTIKEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            12527..12931
                     /locus_tag="VCX65_001382"
     CDS             12527..12931
                     /locus_tag="VCX65_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEP5053842.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDVDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            12933..13211
                     /locus_tag="VCX65_001383"
     CDS             12933..13211
                     /locus_tag="VCX65_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEP5053843.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            13201..13989
                     /locus_tag="VCX65_001384"
     CDS             13201..13989
                     /locus_tag="VCX65_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEP5053844.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAVTLEDQ"
     gene            13992..15302
                     /locus_tag="VCX65_001385"
     CDS             13992..15302
                     /locus_tag="VCX65_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEP5053845.1"
                     /translation="MMSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAA
                     PGGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALTMLKPGGELI
                     YSTCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLTKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFRPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
BASE COUNT         4938 a         2534 c         3189 g         4686 t
ORIGIN      
        1 attaaaagac tattgcttga agaataacag ctgttattct tccttggaca aaaggtacag
       61 gagtatctaa aaaggagaat tatcatggga cttatttgga ctttaatcgt cggtgcgctt
      121 attggtgtga ttgctggagc acttactaaa aaaggcggtt caatgggctg gattgcaaac
      181 atcgctgctg gtctagttgg ttcttccgtt ggtcaagctt tacttggttc atggggccct
      241 tctttagcag gaatgtcttt gatcccgtca gttattggtg ccgttatcgt tgttatgatc
      301 acttcttttg tactaaacaa aactaacaac tagtttcctc tttatttagt aagtacttac
      361 aaatagagaa tgttaagtag aaaagaggtc tgtatgtcaa aattgttaaa gattagttat
      421 tgtcttgtcg gacttgttct attgtctgtt tttggatggg tagttggaat aaccggaggc
      481 tatatatatt taccttatag ttatcgttgg ctaagttggg gtatggatag ttttcccaat
      541 ctcttagatt cagctttatc ctattattac ttctggacag cccttgtatt atttgttata
      601 acatttcttg ccttattagt tattatttta tacccaagaa tttatactga ggtccagtta
      661 cgccataaaa ataaaaaagg aacactttta ttaaaaaaat cggctattga aagttatgtt
      721 gcgaccgcta ttcaaactgc aggtttgatg ccaaacccaa cagtcacagc taaattatat
      781 aagcggaagt ttaagattat cgttaaagga cgtttagctt ctcgtgtagc agtggcagat
      841 caaattagtg gcgtgaaaga agggatcgaa aaaggtttaa ccgagttctt cggtattaat
      901 tatcctgtta atttcaaagt ttatgttaaa gatattgctg attctgatcg taaacatatt
      961 accagaaatc gtgtagaata ggagatctat catggaattt tatgaaaaat tcaagtaccc
     1021 tattattggt ggcttggtgg ggctaattat tgccatattg ctcatggctt ttggtttatt
     1081 caaaacgcta ctagcaatta ttttcattat tttaggaata tatggtggcc tgtatgccaa
     1141 aaaaacaggt attattgatc aatttcttaa tcgcaaataa aggagactta ttatgactga
     1201 aacttatatt aaaaacacat ctaaagactt aacttcagca attcgtggtc aattaacata
     1261 tgatgataaa gtaattgaaa aaattgttgg tttagcactt gaaaatgttg atgggttact
     1321 gggtgtaaat ggtggttttt ttgctaacct aaaagataaa ttagtaaaca ccgaatctgt
     1381 acgtgatggc gtgaacgtgg aagttggaaa aaaacaagtt gccgttgatc ttgatattgt
     1441 cgctgaatat caaaagcatg tgccgactat ttatgactct attaaatcga tcgttgaaga
     1501 agaagtgaag agaatgaccg atctggatgt gattgaagtt aatgttaaag tagtcgacat
     1561 taaaacaaaa gaacaatttg aagctgaaaa agtaagttta caagacaaag tttcagacat
     1621 ggcacgttca acatctgaat ttacgagtca tcaagttgag aatgttaaag cttcagtgga
     1681 taacggtgtt gaaaaacttc aagatcaaaa agctgagcca cgtgtaaaat aatcatatgt
     1741 cgtcaattag gtaagctaaa ggagggttta ttgtgtcaga tgaaaaatat aatgcgaaat
     1801 tagatcaagc tggtggcaag ttaaaagaag gatttggtaa gatttctgga gataaatctt
     1861 tagaaactga aggtaaagta gataaagtta ctggaaaagt taaagaggtt attgcagacg
     1921 ccaaagatac tgtaaaagga ttagctaaag gcttagataa taaagataaa taaaggggac
     1981 atgatggaaa aaactcaaat taaaagcact cttacttatg acgataaggt catcgaaaaa
     2041 attgtcggtc atgctttgga aaacgttggc ggattactag ctgtaacagg tggatttttc
     2101 tcaaatatta aaaataattt ggtgaattct gagtctgtaa ctgatggtgt ttcagttgaa
     2161 gttggtagca aggaagtagc agttgattta gcaatcattg tagaatacgg taaagatatt
     2221 cctgctattg cagaatctat taaagctatt gtttctcaaa acgttgatag tatgacacat
     2281 ttgaaagttg ttgaagtcaa tgtgaacgtt gttgatattc gtactaagga agaacatgaa
     2341 gctgctagcg ttactgttca agatcgtgtc actaatgcag cttcaagtac ttcacaattt
     2401 gtatcagaac aaacggaaaa attaaaagat actatctctg atactgtaaa tagtgatgag
     2461 gcagctaaat aagcaatcgt ctaggaagta ttattgacta gtggtgataa gtttgagctg
     2521 gtatttacca gctctttttg tcacggttaa aaagacacgg actattgtca tctctctaaa
     2581 aatatgattt aattagatag aaatttttca aattgttaga aaggagtaaa ttaagtgata
     2641 agtcctaaaa aagagataac aagttcaaaa tatcaaaaaa ttgctatttc agtagctcag
     2701 cgtatcgcaa atggcgaata tgaagtgggc gaaaagttaa agtcaagaac tactatcgcc
     2761 tcgacattta atgtatcacc agaaacggct cgtaaaggcc tgaatatttt agctgacttg
     2821 aaaattttga ctttaaaaca tggtagtgga gctattgtgc tgtcaaaaga aagagctatt
     2881 gagtttataa atcaatacga atcaacccat tccatcgctg ttttaaaaga aaaaatacgt
     2941 gagactatta atgatcaggg aaaagcaatg gaaaaaatgg ctgttttggt caatgatttt
     3001 ttaatgcaaa gtcaatctgt tagtaagcaa tacccattag caccttatga gattatttgt
     3061 agtcaagatt cggaacattt tggcaaatct attggtgtgt taaatatctg gcaccagaca
     3121 ggagcaacta tcgtcgctat tgaacatgct ggtcagttta tcgtttcacc aggtccttat
     3181 tctgttattg aaaaaggcga tcatatttat ttcgttggtg atgagtcagt catttcacga
     3241 atgaagacct tttttaattt acgaaaagga ttataagttt gagggcccac ctcaaacttt
     3301 ttttgttgct gttgagcatt attaaaagag gcagatcatc atggtttgtc tttccaaaat
     3361 atctgtttag acagttgttt tggattggga gcatgatttc agactctttt gatgtttttt
     3421 aattgtctag agtaactgct ttaagaataa tatcggcaac ctcttcagtg gtttcttgat
     3481 agccattagc aatccaatag ctgataatgc tctcaatact ggcaaggtaa acttctaaag
     3541 catagggata aggaatatgg tattgattgg tcacaatgtc ttggaaacca gtaatagtag
     3601 tcaaaaattg gtaacagaaa tccttgatga gttgcggaaa tttgaggtaa gaaatagtag
     3661 cgagtgcggt tataaattct ctatgttcta taaggtagga caaggtttga ttgaggactt
     3721 gtcgagtgtc tgtgtagatt tcagcctgat ttaacaaacg gtacaaatca tccagagtgt
     3781 catttttgaa atgattcatc atgtcaaatt tatcagtgta gtggaggtag aaggttcctc
     3841 tattgatacc agccttttta gtaaggtcag agacagtaag agtttcaaaa gattgttcag
     3901 ttagtaaggt ggttaaggcg gtctttacat aagctttggt ttcagtatgt cttttggtca
     3961 ttctcaggtg ctccttaaat caacagttgc gtcagatttg ttcttgttaa atacttatgg
     4021 ccattatata ataaggctat aattaaatca acactatgtt caaataatgg aggggcagat
     4081 ggcttttatt gaattaaaac aggtttcaaa atcttatcag gtaggagaga cgactgtttt
     4141 tgccaaccac gaagtgtctt ttgagattaa taaaggagaa ctagtggtta ttttgggagc
     4201 atccggagct ggtaaatcga cagtcctcaa tattttgggg ggcatggaca cagtagatgc
     4261 aggtcaagta attattgatg gcaaagacat tgctcattac acgtctaagg ccttaactca
     4321 gtatcgtcgg aatgctattg gtttcgtttt tcaattttat aatttggttc ctaatttgac
     4381 agctaaagaa aatgttgaat tagcagttga aattgtagca gatgctttag atcctgtgac
     4441 cattttaaag gaagtaggac tcagtcatcg tctggatcat tttcctgctc agctctcagg
     4501 tggtgaacag caacgggttt cgatagcacg tgccttagct aaaaacccta aattgcttct
     4561 ttgtgatgaa cctacaggtg cccttgacta ccaaacagga aagcaaattc taaccctctt
     4621 acaggatatg gcacgaacta aggggaccac ggtagttatt gtaacccaca atgctgctat
     4681 tgctccgata gctgatcgtg tcatttttat gcatgatgca caggttacca agacagtcat
     4741 taataaggaa cctgcaagca ttgagacaat tgattattaa gaggaaggtg tcgtatgata
     4801 aagaaaacct tatggaagga tattttgaga gctatcaaga atagtaaagg gcgattcatt
     4861 tccttatttt tcctaatggc cttaggctcc tttgctttag ttggacttaa agtcaccggt
     4921 ccagatatgg aacgaacagc cagccgttac ctcgaaagac accaggtgat ggacctaacg
     4981 gtactggctt ctcatcaatt ttcccaagcc gataaacaag agttagatac gttaaaaggg
     5041 gctcatttag aatatggtca tttacttgat gtcagtctaa ctagcaacca gaaatctctt
     5101 aggctctata gcgtgccaaa gaaagtgtct aagccagtct tggttaaagg gagttggtca
     5161 aagcgagaga cagatttggt tttatcctcc tcacttgcta aaaactatca gattggagat
     5221 gaactagcag tcacctcacc tatggaaggt ttgctgacga caacccattt tcaagtggtt
     5281 ggttttgcga attcttcaga agtttggtcc aagtccaatt taggaagttc ctcaaccgga
     5341 gatggaagtc tctacgctta tgcttttgtt aatccaaacg tttttaaaag tgcctttaac
     5401 ctgctgcgca tccgttttag taatcttcgt ctgacaaacg ctttttccaa agactatcaa
     5461 aaaagggtaa cccaaaacca agctcatttg gataatctac ttaaagataa tggccagaag
     5521 cgttatgatg acctccaaaa tcagtatgac cttgccttaa aaaatggcag agtagcactt
     5581 gcaaaggaaa cagtgaaact agctgcgagt gaggagaact taactttttt agaaggctct
     5641 gctttacaag aagctaagca tcagattgaa caaggcaaac aagcattagc caaggaggaa
     5701 aagcagttag agcaggtgca ggctacaaaa gataagctag aaaaacccag ttacctgact
     5761 tataatcgct cgaccctacc aggaggagaa ggatatcata cttatgcaac ttcaacgacc
     5821 tccatttcaa atgttggaaa tatttttcct gttgttcttt atctcgtagc tgctctagta
     5881 gcctttacca ccatgacacg ttatgttgat gaagaaagaa caagctctgg tctattaaaa
     5941 gccattggtt attctaacaa ggatatcagt ttaaagtttc ttatctatgg gcttttagcc
     6001 agttttttag ggacaacttt aggtattatt gggggaactt acctcttatc tgccttgatt
     6061 tcagagatct taacaggagc tttgactatt ggaaagactc acctttatag ttattggttt
     6121 tataatggca tagcttactt gctggctatg ttatctgctg ttttacccgc ctacttaatt
     6181 gtcaaaaagg aattattcct caatgcagct cagttattgc tgcccaaacc tcctagtaag
     6241 ggggcaaaaa tctggttgga acaccttact tttgtctgga aagccctgtc ctttactcac
     6301 aaggtgacca tacgtaatat ttttcgctat aaacaaagaa tgctgatgac cattgtaggc
     6361 gttgcaggct cagtagccct tttatttgca ggcttaggga ttcagtcgtc attagccaaa
     6421 gtagttgagc atcaatttgg tgatttaacg acttatgata ttttggctgt cggttcggcc
     6481 aaagcgacag cgacagagca aactgactta gctagctatc ttaaacaaga acctattaca
     6541 gggtaccaaa aggtatctta tgccagctta acccttcctg taaagggatt acctgataag
     6601 caaagtattt ccattttatc aagttcagct acttctctta gcccctattt taatctgctg
     6661 gatagtcagg agcaaaagaa ggttcccatt ccaacctctg gtgttttgat ttctgagaaa
     6721 ttagcctcct attacaaggt aaaaccaggt gatcagttgg tattgactga tcggaaagga
     6781 cagtcttata aagtgacgat taaacaggtt attgacatga cagttggcca ttacctgata
     6841 atgtctaata cctattttaa gaatcatttt aaaggattgg aggctgctcc tgcctatctg
     6901 attaaggtaa aagacaaaga tagcaagcac ataaaggaga cagccagtga cttgttaacc
     6961 ttaaaagcga ttagagcagt ttcacaaaac gccaatcata ttaaatctgt tcagctagta
     7021 gtcacctctc ttaatcaggt catgaccctc cttgtcttct tgtctatttt attagcaatc
     7081 gttatccttt ataacttaac gactattaat attgctgagc gtattcgaga attatccact
     7141 attaaagttc tgggatttta cgatcaggag gtcaccttat atatttatcg agaaactatt
     7201 tcgctatccc tagtaggcat tcttttaggt atctatttag gaaaaggcct gcatacttat
     7261 atcatgacaa tgatttcaac tggggatatt caatttggtg taaaggttga tgcttatgtt
     7321 tatctagtgc caattctagt aatccttagc ttgttagcgg tattaggtat ctgggttaat
     7381 cgccatttaa aaaaggttga tatgttagaa gctttgaaat ccatagattg attggtgaaa
     7441 agacagatat agacagcact tgaaaagtta atcatattat gatagtatct aaatactata
     7501 atttaataga aagatactat gtatggaaaa tagcattgag gcctatctag cagatagcag
     7561 agaaaaggta acattaggta cagttgttga ttgttttaaa ggaaaagcag tctcaagtaa
     7621 ggttgtgcca ggtgatgtgg gattggttaa tttatctgac atgggcacct tagggattca
     7681 atatcaccaa ttaagaactt tccagatgga tcgtaggcag ctcttgcgtt accttttgga
     7741 agacggagat gtcttaatcg cctctaaggg aaccctaaaa aaagtctgtg tttttcataa
     7801 gcaaaatcga gatgtggtgg catcatcaaa tatcactgtc ttacgccctc aaaaactgtt
     7861 aaggggctac tatatcaagt tctttttgga ctcacctatt ggtcaagcgc tcttggacgc
     7921 agcggaccat ggcaaagatg tgatcaatct ctcaacgaaa gaattgttgg atattccaat
     7981 tcccgttatt cctttagtga aacaggacta tttgattaat cactacttga gaggattaac
     8041 agattatcat cgtaaactca atcgagcaga acaggagtgg gaatatattc agaatgaaat
     8101 tcaaaaagga ttaggttagg agtcttgtca tgggttcagt tgaacgtaca ttaaaaatga
     8161 ccttggctac cattgttgcc attttaattg cttaccaact tcatctggat tatgcaatgt
     8221 cagcggggat cattgccctg ttaagtgttt tagacacccg taagtccagt ttggtggtcg
     8281 ctaggaatcg cttgctatct tttttcctgg cttttgggat tgcgatgatg tgctttagct
     8341 tgtttggttt tacgacagta ggttttatgt gttatttgtt aattattatt cctttgctct
     8401 atcactttca gatagaggca ggactggttc ctataacagt acttgtgaca catttgattg
     8461 ctaaaaagag tattgcatta cctattttat cgaatgagtt tatgctcttt tttgtaggga
     8521 ctagtgtcgc tttactattt aatgcttata tgggtccaca agatcagcaa attcggtact
     8581 atcaccaaaa agttgaatcg gatctgaaag gtatcttata ccgttttgaa agttttctac
     8641 tggaaggaaa aggtcaaaat gaagggctct tgatcaaaaa ccttgataaa atattagatg
     8701 aagctctaaa actagtttat cgagaaaggc ataatcaact atttcagcag accaattatc
     8761 aagttcatta ttttgagatg cgacgacaac aaaatagact attgggacaa atggctatca
     8821 acgtaaacac gttaatgaga caaagtaagg aaagtattct tttgtcacat ctttttcacg
     8881 aaactgcttg tcagctaagc gaacaaaatc cggctttaac cttgattgat gatatcgaac
     8941 aattgcttga aacctttcgt catggtgatc ttcctcaaac tcgggaggaa tttgagcgac
     9001 gtgcggtttt atttcagctc ttacaagact tggaacgttt tatcttatta aaggtagagt
     9061 tttatcagga ttatcaaaat gactaaatct ctattgcaca cttcttatct atgacagctt
     9121 gggacttaac ttcctgagct tttttgctat aataaaaaca agaatctcag aatggagaca
     9181 agatgaacga aataaaatgc cctcattgtc ataccctatt tactatcaat gagtcagagt
     9241 atagtcaatt attggaacaa gtcagagggc aagcctttga tgaagaattg caaaaacggt
     9301 taatcaatga gatggccttg ctggaagaaa aagcgaagca tcaattgcat gaggttgtcg
     9361 caaaaaaaga aacagctatt accagcttga caaaccaatt agagcaaatt gaaaaagaac
     9421 aagcctacct cagacaagaa gaactggcta aaaaagacca gcttattgct tctttagaag
     9481 cgaaacttga taaattagcc tcacaaaatg ctttggaact ggccaatcaa ttagctgaga
     9541 aggacaaaga agtggttagt ttgaccaatc agctggacaa attagcactt gaaaaagatg
     9601 ccacgttcca gtcaaagctt gctacaatcg aaaaagaacg cgatggaatc aaaaaccaat
     9661 tggcgcttca agctaaagaa agtgaattgt cgttggcttc ggtgcgcagc gactacgaag
     9721 cacagttaaa agcggctaac gagcgagttg aattttataa aaatttcaaa gcgcagcaat
     9781 ctaccaaggc tatcggagag agtctagaac tctatgctga aacagagttt aacaaagtaa
     9841 gaagctatgc ttttcccaat gctagctttg tcaaagataa ccaattgtct agtcgtgggt
     9901 caaaagggga ctatatttac cgagaggttg atgccaatgg tgtagaaatc ctctctatca
     9961 tgtttgaaat gaagaacgag gcagacacca ccaaaacaaa acataaaaat agtgattttt
    10021 tcaaggagtt agataaagac cgtcgcgaaa aagattgtga gtatgctgtt ttggtaagca
    10081 tgttagaagc tgataatgat tactacaata cagggattgt tgatgtcagt catgagtatc
    10141 aaaagatgta tgtggttcgt cctcaactct ttattcagtt gatagggatt ctgcgaaatg
    10201 cagccctgaa tagtttacat tataagcaag agttggcctt gattaaggaa caaaatattg
    10261 acatcactca cttcgaagag gatttggatc aatttaagaa tgcctttgct aagaactatc
    10321 agtctgccag caacaacttt aaaaaggcta ttgacgagat tgataaatcg attaaacgca
    10381 tggaggaagt gagacgcttt ttaaccacta gtgaaaatca gttacgctta gctaataata
    10441 aattagagga tgtttcagtt aaaaaactga cccgccaaaa cccaaccatg cgagagaaat
    10501 ttgcagccct caaggaccag taagcctgaa agtgagtctt tccctgctaa aattggttaa
    10561 gcgtttattt tggcaaaact gatgataaag cggtagaata gaatcagtaa caattactaa
    10621 ttagagagaa aaatagacat gataaatgga atcattaatt taaaaaaaga agccggcatg
    10681 acctctcatg acgcagtttt taaattacgg aagttattac aagaaaaaaa gattggacat
    10741 ggggggacct tagatcctga tgtggtcggt gttctaccaa ttgcagttgg taaggctact
    10801 cgtgtgatcg aatacatgac agaagctggt aaagtttatg aaggacaagt gactctcggt
    10861 tactcaacaa cgactgagga tgctagtgga gaggtagttg cgagatcttc tttgccagct
    10921 gtgctaacag aagaactcgt tgatcaaacg atgacgactt ttcttgggaa aatcacacag
    10981 accccaccta tgtattcagc cgtaaaggtt aatggccgta aattatacga gtatgcgcgt
    11041 actggtgaaa gtgtggaacg tcctagaaga gaagtgacca tttctctgtt tgaacgcacc
    11101 agccctttga attttactga agacggtctt tgccgattct cttttaaagt tgcttgtagc
    11161 aaggggactt atgtgcggac cttagcagtt gatttaggtc gagctctatg ggtagagagt
    11221 catatgtcct tcttgcagcg atcagcttca gcaggattaa ccctcgagac tgcctatact
    11281 ttgggagaaa ttgctgatat ggtttctaaa caagagatgt cttttttgtt accgatcgag
    11341 tatggcgttg ctgatcttcc taaaatggtt attgatgata ctgaattgac tgaaatttca
    11401 tttggtcgcc gtcttagtct ccctagtcaa gagccactgt tagctgcttt tcatggcgaa
    11461 aaagtaattg ctattttaga aaaaagagat caagaataca aacccaaaaa agttcttatt
    11521 taaatagttt gagtaagtag aatggataat tatggaaatt gaatatatca aagattatcg
    11581 tgatattaac caagaagatg atacagtctt ggtattggga tattttgatg gattacaccg
    11641 tggtcataaa gccttatttg aaaaagcaag agaggttgca aataaagaag ggttaaaagt
    11701 agtcgttttt acgtttacag agtctccgaa attggctttt tcgcgttttt ctcctgagtt
    11761 attgcttcat attacttatc caaagaagcg ttatgaaaaa tttgccgatt acggtgtaaa
    11821 taaattatat ttggttgatt ttacttctaa attctctaag gtctcatctg atcattttat
    11881 aactcattat attaaaaacc tgaaagcaaa gcatattgtt gtcggttttg actataagtt
    11941 tgggcataat tgtacagata gtgattattt aaccagaaat tttgaaggac aagtttatac
    12001 cattaaggaa ataaaagaag atcatcgaaa aatttctgct acatggataa ggaagcttat
    12061 tcaagaaggt aatgtagtta aagcaaacca cttgttaggc tatgacttat cgacaagggg
    12121 gagagtcgtt cacggggatg cgcgtggccg tactattggt ttcccaacag ccaatctagc
    12181 tccaattgac aacacatact taccagctga tggagtctat gttacaaatg ttattgttgc
    12241 taataaaatc tatcgctcta tgacgagttt aggtaaaaat gtgacatttg gggggaaaga
    12301 gttgcgtcta gaagttaaca tttttgactt tgacgaagag atctatggag aaattattga
    12361 gattgtttgg ttagataaga ttcgagacat ggaaaaattc gagggaatcg aagatttgac
    12421 tgatagattg gaatatgata aacgaacagc attaaattgg aaaaaagata gcaaattatc
    12481 ttaaattttt gtataataag gtaagtaaat ttgatagagg aaaaatatgg ttaccttatt
    12541 tttatcacct agctgtacca gttgtcgtaa agcaagggca tggttagtaa aacacgaagt
    12601 tgactttcaa gagcataata ttattacaag tccattaagc cgtgatgaat taatgtcaat
    12661 cctctctttt acagagaatg gaacggagga tattatttca acacgttcaa aggtttttca
    12721 aaaacttgat gttgatgtag aagagctttc aatttcagat ttaattgatt taattgctaa
    12781 aaatccaagt cttcttcgtc gccctattat catggatcaa aaacgcatgc aaattggttt
    12841 taatgaagat gaaattagag cgtttttatc gagagattat cgcaagcaag aactacgtca
    12901 agcaacgata aaagcagaaa ttgaggggtg atatgtcagg taattattat tatccacttg
    12961 acttaagttg gagcactgaa gaaatatcct cagtgcttca ttttttgaat aaagtggagt
    13021 tagcatatga aaaaaaagta gatgcaaaac aactcctaga tagttataag acttataaaa
    13081 ccattgtcaa aagtaaagct caggaaaagc aaatcgaccg tgattttcaa aaagttagtg
    13141 gttattcgac ctatcaagtt gttaaaaaag cgaaggcaat tgagaaagga ttcttttccc
    13201 ttggaaacta aatacgcatt tgcaaggcaa atcattaaag aagcagggct ttttatcaag
    13261 tcaaaaatgt cagagcagct agatattcag gtgaaaacac aatttgatga tctggttacc
    13321 aatgttgatc aagaaactca acagttactg atggatcgta ttcatcagac ctatccttgt
    13381 gatgccattt tagctgaaga aaatgacgtt cgtcacccca ttaatcaagg aaatgtttgg
    13441 gtcatcgatc ccattgatgg aacggttaac tttattgtgc agggatcaca gtttgcagtg
    13501 atgattgcct attatgaaca aggaattggc caatttgggc ttatttatga tgtgatggca
    13561 gatcaattac tagctggtgg tggtgatttt gaagttactt taaacggtga taagcttcca
    13621 gcttaccaag aaaaaccttt agagcgtagc ttaattggct gcaatgcagg catgtttgcc
    13681 agaaatgatc gtaaccttgc tcatctaatt gcaaagactt taggtgtaag ggtttatggt
    13741 ggtgcaggta tctgcatggt taaggtcatg aagcaggaat tactggccta tttttcattt
    13801 atccaaccat gggattacgc agcagcaaaa gtactaggcg ataaactggg ttatgtttta
    13861 ctaactattg acggatatga gcctgatttt caaacacgtc aaaaaatcat gtttgttcct
    13921 aaatgccaac tcactaggat agcgtctttt ctaacaaagg actctgccgt cacacttgaa
    13981 gatcaataga aatgatgtca ttaccaaaag aatttattaa cacttatcaa gcaatactag
    14041 gcaaagaatt agaagatttc ttggcaagtt ttaaccaaga gccggtcaat gcttttcgga
    14101 ttaacccctt aaagaatcaa ctaaaaacct ttgaacaccc cattccaaat accttatggg
    14161 gatattatgg taaactatct ggcaagtctc cagagcatgt gtcggggttg gtttattccc
    14221 aagaaccagc ggctcaaatg gtggcacaag tagcggctcc tcaaaagggg agtcgtgttt
    14281 tagacttggc agctgcacca ggaggaaaat caactcattt attagcttat ttagacaata
    14341 caggtctttt agtcagcaat gaaatttcta agaagcgcag caaggtttta gttgaaaata
    14401 tcgaacgttt tggcgctaga aatgttgtgg tgactaatga atccgcagat cgtttagcca
    14461 aggtattttc tcattatttt gatactatcg tctttgatgg accatgttct ggtgaaggaa
    14521 tgtttcgcaa ggaccctgat gctattcaat attggcatca cgggtatccc gcagaatgcg
    14581 ccaagttgca aaaatctatt ttagaagacg ccttaaccat gttaaaacca ggaggagaat
    14641 tgatatactc cacctgtact tgggctcctg aagaaaatga agatgttgtg cagtggctct
    14701 tagagactta taccttttta gaattggtcg atgttccaaa actaaatgga atggttagtg
    14761 gtatcggact tccagagact gctagaatgt accctcatcg ttatcaaggg gaagggcaat
    14821 ttgtggccaa gctaaaagat aagcgtcaag aaggacaaag cactaaacta aaagcaccta
    14881 aatccaactt gaccaaagac cagttacgtc tttggaaaat gtttgaaaaa gaccatctaa
    14941 accttaccct atcaggaaca ctacaaacct ttggtgatta cctatacctc ttgccagatg
    15001 gtcttcctgc tttagatggc cttaaaattg ctcggaacgg tttagaatta ggcgtcttca
    15061 agaagaaacg ctttgaaccc tcttacgcct tgggattagc tttaaagcct gatgaggtcc
    15121 gatcatctat tgagcttaga gaggaagact ttagacctta tgtgtcaggt aacgtcatta
    15181 ctttgcccca atcttatcca acaggctggt accaattact cattaatggc aatggtctag
    15241 gatttgccaa ggtcgttgac aagaccatca aaaataattt ccctaaaggg ttaagatttt
    15301 agcgtaaaaa ataatattaa aaagttaaat atttaaagaa aaaatgc
//
LOCUS       DATWVB010000037        15180 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.037, whole genome shotgun sequence.
ACCESSION   DATWVB010000037 DATWVB010000000
VERSION     DATWVB010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15180
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.037"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            83..787
                     /locus_tag="VCX65_001386"
     CDS             83..787
                     /locus_tag="VCX65_001386"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEP5053846.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVIAGSFSK
                     RFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            911..4636
                     /locus_tag="VCX65_001387"
     CDS             911..4636
                     /locus_tag="VCX65_001387"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEP5053847.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIESLPGQFDQRAVSSQE
                     ALLLFGSDSQVKVNTAQLYLVNKDIAEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFETYKADDFTAYKVEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRAGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNDETIVDLERRFLDTNGVRVVVDAKVVDKDLTV
                     PEARITSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNAYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKILSPEFKAAGENIYYIPGQAISEDIDFDLIKANFSQFEAIQTQHKIT
                     AASAVKYGGVLESFALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQTDVLEEVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGASVNLVPFVTLNEVAIAESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK"
     gene            4797..6251
                     /locus_tag="VCX65_001388"
     CDS             4797..6251
                     /locus_tag="VCX65_001388"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEP5053848.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNSSFMGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDRGIQCDRYTDETQLAICSMEYVYFARPDSTIHGVNVHTARKNMGK
                     RLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHAADEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            6279..7301
                     /locus_tag="VCX65_001389"
     CDS             6279..7301
                     /locus_tag="VCX65_001389"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEP5053849.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVREPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNNPVKFEEVVSGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQLIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVRAALPLIKEELINGIGHITGGGFIENVPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     DSVVIK"
     gene            7469..8023
                     /gene="purN"
                     /locus_tag="VCX65_001390"
     CDS             7469..8023
                     /gene="purN"
                     /locus_tag="VCX65_001390"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEP5053850.1"
                     /translation="MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKAAYEQAIVDLLDKHEIDLVCLTGYMKIVGETLLLAYEGRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            8207..9754
                     /gene="purH"
                     /locus_tag="VCX65_001391"
     CDS             8207..9754
                     /gene="purH"
                     /locus_tag="VCX65_001391"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEP5053851.1"
                     /translation="MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVVLKHM
                     NPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(9812..10936)
                     /locus_tag="VCX65_001392"
     CDS             complement(9812..10936)
                     /locus_tag="VCX65_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEP5053852.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIKVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFTVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
     gene            11189..12454
                     /gene="purD"
                     /locus_tag="VCX65_001393"
     CDS             11189..12454
                     /gene="purD"
                     /locus_tag="VCX65_001393"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEP5053853.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGVPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFVNGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVRPVLEGMVAEGRPYLGVLYVGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVA
                     SEGYPLDYEKGVPLPEKTDGDIITYYAGAKFVENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDTTGLFYRNDIGSKAIRE"
     gene            12732..13223
                     /gene="purE"
                     /locus_tag="VCX65_001394"
     CDS             12732..13223
                     /gene="purE"
                     /locus_tag="VCX65_001394"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEP5053854.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            13210..14283
                     /gene="purK"
                     /locus_tag="VCX65_001395"
     CDS             13210..14283
                     /gene="purK"
                     /locus_tag="VCX65_001395"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEP5053855.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGYKVITLDPASDCPASRV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENIDADGLDAVVSACQLPQGTDLLRISQNR
                     IFEKDFLANKAGVTVAPYKVVTSSLDLGGLDFTKTYVLKTATGGYDGHGQKVIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGEDVTVFPVQENIHCNNILSKTIVPA
                     RISDQLADKAKKMAVQIAKKLQLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPTIHLHAPAVMLNVLGQHVQQAIDYVAQNPSAHLHMYGKLE
                     AKHNRKMGHVTVFSDLPDEVEEF"
     gene            14285..>15180
                     /locus_tag="VCX65_001396"
     CDS             14285..>15180
                     /locus_tag="VCX65_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053856.1"
                     /translation="MYLKYIFKIKDRNLVSDYESLVRNLTINLQKLVIKDRTALIGDK
                     QLPITIYYRGENEKFPTGIVKVESDSVEGLELFDKTIKEIVGNESRFGKFTCIYDGIS
                     TYYSTEIYSELHEIERRTQEFLREAFFLSDKSGELKEYQATIKKMDSSDFSFSKLINE
                     IFKASDITDTFIDHVRACVEFGTVPNGDLLPKSFWDSLDDSLLDDKEQGLEINNLLNE
                     IRSTRNTIAHCKEFKKKDYINCIEQVKKLKQALDKIIASIESTDISKMSREVSRINNS
                     LQADNDYIKQKYFIEYDIFEKD"
BASE COUNT         4400 a         2927 c         3536 g         4317 t
ORIGIN      
        1 ttataaacgt aaataatatc ttgaatattt ttatagagta tgttactctt aaatgaaaac
       61 agaaagaaag gcgaataatc aagtgactaa ccagcttatt tataaaggaa aagcgaaaga
      121 tatttatagt acaaaagatg aaaatgtgat tagaacggtc tataaagacc aagctactat
      181 gttgaatgga gctcgtaagg agactattga tggcaaggga gcactaaata atcagatttc
      241 atctcttatt tttgagaaat taaataaggc tggtgtggtg acacattata ttgagcaaat
      301 ttcaaaaaac gaacaattga ataaaaaagt tgatattatt ccacttgagg tggtgttacg
      361 gaatgtgata gcaggctcat tttcaaaacg ttttggagtg gaagaaggac gtgttcttga
      421 aacgccaatt gtggaatttt actacaaaaa tgatgatctg aatgatcctt ttatcaatga
      481 tgagcatgtg aagtttttgg gtattgttaa tgatgaggag attgcttatc tgaaaggaga
      541 gactcgccgt attaatgaac tcttgaaagg ttggtttgct cagattgggc ttaacttgat
      601 tgacttcaag ttggagttcg gatttgatca agaaggtaca attatcttag cagatgaatt
      661 ttcgcctgat aactgtcgcc tatgggataa gaatggtaac catatggaca aggatgtttt
      721 tagaagagac cttggcaacc tgacggatgt ctatcaagtt gtacttgaga agttgatagc
      781 attgtaacta gaagaggaag gaattgaatc cgttcgggaa actccgaaaa aaagatggaa
      841 cttactgaaa tctcaatttc agatgtcctc ctattttcca gtcgctccct tgtcggactt
      901 ggtatcttat atgaataaac gtatttttgt tgagaaaaag gctgactttg gtattaaatc
      961 ggctagcctt gtgaaagagt tgacgcataa tctacaactg acttctttga aggctttgcg
     1021 tattgtgcag gtctatgatg tcttcaattt ggctgaggat ttgctggcgc gtgctgagaa
     1081 gcatattttc tctgagcagg tgacagactg tcttttgacg gaaactgaaa tcactgcgga
     1141 gcttgataag gttgccttct ttgccattga gtcgcttcct ggtcaatttg accaacgtgc
     1201 tgttagttcg caagaagctt tgctattatt tggaagtgac agtcaggtta aggtcaatac
     1261 agcccagctt tacttggtca ataaggatat tgcagaagca gagcttgaag ccgttaagaa
     1321 ctatcttttg aaccctgttg attcgcgttt caaggacatt actttgccgc ttgaagagca
     1381 ggctttctct gtgtctgata agacgatccc taatcttgat ttcttcgaga cttataaggc
     1441 tgacgatttt acggcttata aggtagagca gggcttggct atggaggtcg atgatcttct
     1501 cttcatccaa gattatttca aatcaatcgg gcgtgtgcca actgagactg agttgaaagt
     1561 tttggatacg tattggtcag accactgtcg tcacacaacc tttgaaactg aattgaagaa
     1621 cattgatttt tcagcttcta aattccaaaa acaattgcag acaacttatg acaaatatat
     1681 cgccatgcgt gatgagcttg gtcgttctga aaagccacaa acacttatgg atatggcgac
     1741 tatttttggt cgttatgagc gtgccaacgg tcgtctggac gatatggaag tctcagatga
     1801 aatcaatgcc tgctcagttg agattgaagt agatgttgat ggtgtgaaag agccttggct
     1861 cctcatgttt aagaatgaga cacacaatca cccaacagaa attgagccat tcggtggagc
     1921 ggcgacttgt atcggtggtg ctattcgtga cccattgtca ggacgttcat acgtttatca
     1981 ggctatgcgt atttcaggcg caggcgatat cacgactccg attgcggaaa cacgtgctgg
     2041 taaattgcca caacaggtta tttctaagac tgcggcgcac ggctattctt catatggtaa
     2101 ccaaattgga cttgcgacaa cttatgtgcg tgagtacttc caccctggct tcgtagccaa
     2161 acgtatggag cttggagctg tggttggtgc tgcacctaag gaaaatgtgg ttcgtgaaaa
     2221 accagaagca ggtgatgtgg taatcttgct tggtggtaaa acagggcgtg acggtgtcgg
     2281 cggtgcgaca ggttcatcta aggttcaaac ggttgaatct gtggaaacag caggagcaga
     2341 ggtacaaaaa gggaatgcca tcgaagagcg taagattcaa cgtcttttcc gtgctggcaa
     2401 tgtcactcgt ctgatcaaga aatcaaatga cttcggtgca ggtggtgtct gtgttgccat
     2461 cggtgaattg gctgacggtc ttgaaatcga tttggacaag gtgcctctta aataccaagg
     2521 tcttaatggt actgaaattg caatctcaga atctcaagag cgtatgtcag tcgttgttcg
     2581 tccaagtgat gtggatgcct tcatcgcagc ctgcaacaag gaaaatatcg atgcagtcgt
     2641 agttgcgact gtgactgaaa aaccaaatct tgtcatgact tggaatgatg aaacaattgt
     2701 tgatttggaa cgccgtttcc ttgataccaa tggtgtccgt gtcgttgttg atgctaaagt
     2761 cgttgacaag gacttgacag ttccagaagc acgcataaca tcagcagaga cacttgaagc
     2821 agatacgctt aaggtcttgt ctgacctcaa ccatgctagt caaaaaggtc tccaaaccat
     2881 ctttgactca tctgttggtc gttcaaccgt taaccaccca atcggtggtc gttaccaaat
     2941 cacaccgaca gaaagttctg ttcaaaaatt gccagttcaa catggtgtga caacaactgc
     3001 atctgttatg gctcaaggtt acaatgctta tattgcagag tggtcacctt atcacggtgc
     3061 tgcctatgct gttattgaag cgacagctcg cttggtagca acaggtgctg actggtctcg
     3121 tgcacgtttc tcttaccaag agtatttcga gcgtatggat aaacaggcag agcgttttgg
     3181 tcagccagta tcagctcttc ttggttctat tgaggctcag attcaacttg gcttgccatc
     3241 aatcggtggt aaggactcta tgtctggtac tttcgaagac ttgacagtac caccaacctt
     3301 ggtagctttc ggtgtgacaa cagcggacag ccgcaagatt ctctctcctg agtttaaagc
     3361 ggctggtgag aatatctact acattccagg tcaagctatt tcagaagata ttgattttga
     3421 ccttatcaag gctaacttca gtcagtttga agctattcaa actcaacata agattacagc
     3481 tgcctcagcc gttaaatacg gtggtgtcct agaaagtttt gctctcatga cttttggtaa
     3541 ccgtatcggt gcttctgttg aaattgcaga gcttgacagc agcttgacag ctcaactcgg
     3601 aggttttgtc tttacatcag ctgaggaaat tgctgacgcg gtgaaaattg gtcaaactca
     3661 ggcagacttt acagtcactg tcaatggaaa tgaccttgct ggcgctagcc ttctagcagc
     3721 cttcgaaggc aaattggaag aggtttaccc aacagaattt gaacagacag atgttcttga
     3781 agaagttcct gctgtggtat cagatactgt tatcaaggct aaggaaacaa ttgaaaaacc
     3841 agtggtttac attccagtct tccctggtac caactcagag tacgattcag ctaaggcctt
     3901 tgaacaggtt ggagctagtg tcaacttggt accatttgta accttgaatg aggttgctat
     3961 tgctgagtca gttgacacta tggttgctaa tattgctaag gcaaatatca tcttctttgc
     4021 tggaggtttc tcagcagcgg atgaaccaga tgggtctgct aagtttatcg tcaatatctt
     4081 gcttaacgag aaggtccgcg cagctattga cagcttcatc gaaaaaggtg gccttatcat
     4141 cggtatctgt aatggtttcc aagcccttgt taaatcaggt cttcttccat acggaaactt
     4201 cgaggaagct ggtgagacaa gtccaactct cttctataac gatgctaatc agcatgttgc
     4261 caagatggtt gagactcgta tcgcaaatac caactcacct tggttggcag gagttgaggt
     4321 cggcgatatt catgccattc cagtttcaca tggtgaaggt aaatttgttg tcagcgcttc
     4381 tgaatttgca gagctaagag acaatggtca aatctggagc caatatgtgg actttgacgg
     4441 acaaccatct atggattcta aatacaatcc aaacggctct gtcaatgcca tcgaagggat
     4501 taccagcaag aatggtcaaa tcatcggtaa gatgggacac tcagaacgct gggaagacgg
     4561 actcttccaa aatattcctg gtaacaaaga ccaaaccctc tttgcaagtg ctgtaaaata
     4621 ctttacaggg aagtaaaaag gttcagtgaa cctttttagc cctcgccttg aattagtgaa
     4681 gggcaaggtt agaaagaatc tcgcttaatt tttgagaaat agtaaacacg ggcgataagt
     4741 tgtgcgaaaa actttctatt ttcgctttac ttgacagcct ttgtatcgag gtaaaaatga
     4801 catacgaagt aaaatctcta aatgaagaat gtggagtctt tggtatctgg ggacatcctc
     4861 aggcagctca agtcacttac tttgggcttc atagccttca acatcgcggt caagaaggag
     4921 ctggtattgt ttcaaatgac aatgggaaac tctatggtta tcgaaatgtt gggctccttt
     4981 ctgaagtttt taagaatcaa tctgaattag ataatttaac tgggaatgcg gctattggac
     5041 atgttcggta tgctactgca ggttctgcag atattcgcaa tattcagcct tttctttata
     5101 aatttcatga cgggcaattt gctttatgcc ataatggtaa tttgacaaat gctatttcct
     5161 taaggaaaga attagaaaag caaggtgcaa ttttcaatgc ctcctcagat actgaaattt
     5221 tgatgcactt gattcgtcga agccataact caagtttcat gggaaaggta aaagaagctc
     5281 taaatacagt aaagggtggc tttgcctatc tactgatgac agaaaataaa ctcattgctg
     5341 ctcttgaccc taatgccttt cgtcctttgt caattggaca aatgcaaaat ggtgcctggg
     5401 ttatttccag tgagacctgt gcttttgagg tggtaggcgc aaaatgggtt agagatgttg
     5461 aacctggcga agttattctt atagacgatc gtggtattca atgtgatcgt tatactgatg
     5521 aaacgcaact ggcaatttgt tcgatggaat atgtctattt tgcaaggccg gattcaacta
     5581 tacatggtgt taatgttcat acggctcgaa aaaatatggg aaagcgtctt gcacaagaat
     5641 ttaaacagga tgctgatatt gtaattggtg tcccaaattc gtccttatcg gctgctatgg
     5701 gctttgctga agaatccgga ttaccaaatg agatgggtct tgtaaaaaat cagtatacgc
     5761 agcgaacctt tattcaaccg acacaagaat taagggaaca aggtgttcga atgaaactat
     5821 cagcggtatc tggtgttgtc aaaggaaagc gcgttgttat gattgatgac tcaattgtaa
     5881 gaggaacgac ttctagaagg attgtcggat tattaagaga agcaggagct agtgaagtac
     5941 atgttgctat agctagtcca gaattaaagt atccttgttt ttatggtatt gatattcaaa
     6001 caagacgaga attaatttca gcaaatcacg ctgctgacga agtgtgtgat attattggcg
     6061 cagatagtct gacctatctc tcactagatg ggttgattga atcaattgga ctcgaaacaa
     6121 aagcaccaaa tggtggttta tgcgtagctt actttgatgg acattatcca acaccgcttt
     6181 atgattatga agaagaatac ctcagaagtt tagaagaaaa aacaagtttt tatattcaaa
     6241 aagtgaaata agctctgcta attatataag gagaaaacat gtctgaaaaa aatgcttatg
     6301 caaaatctgg tgttgatgtt gaagctggtt atgaagtggt tgaaagaata aaaaaacacg
     6361 ttgctcgtac agaacgtgcg ggagtcatgg gagctctagg tggctttggt gggatgtttg
     6421 acttgagtaa aacaggagtt agagagcctg ttttggtctc agggacagac ggtgttggca
     6481 caaaactcat gcttgctatc aagtacgaca agcacgacac aatcggtcaa gactgtgttg
     6541 ccatgtgtgt caatgatatt attgcagcag gtgctgagcc cctttacttc cttgactacg
     6601 tagcgacagg aaaaaataat ccagtcaaat ttgaagaagt tgtttctggc gttgcagaag
     6661 gttgtgttca agcaggagca gcactcattg gaggtgagac cgctgaaatg cctgggatgt
     6721 atggcgaaga tgattatgac cttgctggct ttgctgttgg tgtggctgaa aaatctcagc
     6781 tcatcgacgg ttcaaaagta aaggaaggcg atattctttt gggacttgct tcaagtggta
     6841 tccattcaaa cggttattct ttggtacgtc gtgtctttgc tgactatact ggtaaagagc
     6901 tgcttccaga acttgaagga aaacaactta aggatgtcct tcttgagcca actcgtattt
     6961 atgttagagc agctctgcca ttaatcaagg aagaactaat caacggtatc ggccacatca
     7021 caggtggtgg ctttatcgag aatgttcctc gtatgtttgc agatgatttg gctgcggaaa
     7081 tcgatgagga caaggtgcca gtgcttccga ttttcaaggc gcttgaaaaa tatggtgaca
     7141 tcaagcacga agaaatgttt gaaatcttca atatgggtgt cggtcttatg ctagctgtta
     7201 gtcctgaaaa tgttaaccgc gtcaaagagc tcttggatga accagtttat gaaatcggtc
     7261 gtatcatcaa gaaagcagac gatagtgtgg tgattaaata agtcactaaa ttttataaga
     7321 aaggagtgtt tagttagttt gcctaactga acacgggatt aaatttctag gaaaaaagat
     7381 aaaatgactt agacgcaagc gtcgttgttc gttttcctat ttttctacga aatttttcgg
     7441 caagccgaat catccctttg tatcgaatat gaaaatcgct gtttttgctt ctggtaatgg
     7501 ttccaacttt caggtcatag cagagcagtt tccagttagt tttgtctttt cagatcatcg
     7561 tgatgcctat gttttagagc gtgctcagaa tttagccatt ccaagcttcg cttttgaact
     7621 caaggagttt gagaataagg cggcttacga gcaagccatc gttgatttgt tggacaaaca
     7681 cgagattgat ttggtctgtc taacgggcta tatgaagatt gttggagaaa ccttactctt
     7741 ggcctatgag gggcgtatta tcaatattca cccagcctac ctgcctgaat ttccaggtgc
     7801 ccacggtatc gaggatgctt gggaagctgg tgttgaccag tctggcgtga ccatccactg
     7861 ggttgactct ggtgtggata ccggtcaggt catccaacaa gtgcgcgtgc cacgcctagc
     7921 agacgatagc ctagaaagct ttgaaacccg tatccatgaa accgaatatc aactctaccc
     7981 agctgtctta gatagcttgg gagtggagag gaaagtaatc tagcctttat cttaaaattt
     8041 taggtaaagt taggaaagat agtaaagaag aattaacgtt ccaaaaagaa aggaattgaa
     8101 cccgtctgga aggcacagaa aaaagataaa catctcctag gcgcaagcgt cttcgtcgag
     8161 tttcctattt ttccttggcc ttctagtcgg acttggtatc ttaaatatga ctaaacgtgc
     8221 tttaatctca gtgtctgaca agtcaggaat tgttgacttt gcaaaagaat tgaaaaactt
     8281 gggttgggat attatctcaa ctggtgggac taaggttgcc cttgataatg ctggcgttga
     8341 gaccattgcc atcgacgatg tgactggatt cccagagatg atggacggtc gtgttaagac
     8401 cctccaccca aacattcacg gtgggctttt ggctcgtcgc gacgctgaca gccaccttca
     8461 ggctgctaag gacaacaata tcgagctgat tgacctcgtg gttgtcaacc tctatccctt
     8521 caaggagact atccttcgtc cagatataac ctatgatttg gcggtggaaa acatcgacat
     8581 cggcggtcca tcaatgcttc gctcagccgc taaaaatcac gctagcgtga ccgttgtggt
     8641 tgacccagcg gattatgcga ctgttttggg agaattggct gacgctggtc agacgacatt
     8701 tgaaacgcgt caacgcttgg cagctaaggt ctttcgtcac acagcagcct acgacgcttt
     8761 gattgctgag tacttcacaa ctcaagtggg agaggctaag cctgaaaaat taaccatcac
     8821 ttacgacctt aaacaggcta tgcgttacgg agaaaatcca caacaagacg ctgatttcta
     8881 tcaaaaagcc ttgccaacag actactcaat tgcttctgct aaacagctca acggaaaaga
     8941 attgtccttc aataatatcc gtgatgccga tgcagcaatc cgtattatcc gtgatttcaa
     9001 agatcgtcca actgttgttg tcctcaaaca catgaaccca tgtggtatcg gacaggctga
     9061 tgatattgag acagcttggg attacgctta tgaagctgac ccagtttcaa tctttggtgg
     9121 aattgtcgtc cttaaccgtg aagttgacgc agcgacagct aagaagatgc accctatctt
     9181 cttggaaatc atcatcgcac catcatactc agaagaagcg ctagctattc tcacaaataa
     9241 aaagaaaaac ttgcgaatcc ttgagttgcc gtttgatgcc caagctgcca gcgaagtgga
     9301 agctgagtac actggcgtag ttggtggact tttggtgcaa aaccaagacg ttgtggctga
     9361 aaatccatct gactggcaag tggtgacaga ccgccaacca acagaacaag aggcgactgc
     9421 ccttgagttt gcctggaagg ctatcaagta tgttaagtct aacgggatta ttattactaa
     9481 cgatcacatg acgcttggac tcggtgcagg tcaaaccaac cgtgtcggct cagtcaagat
     9541 tgctatcgag caggctaaag accaccttga cggtgccgtt ctagcatcag atgccttctt
     9601 cccatttgcg gacaacattg aagaaatcgc tgccgcaggg atcaaagcaa tcatccaacc
     9661 aggtggttca gttcgtgacc aagactctat tgacgccgca aacaaacatg gcttgaccat
     9721 gatcttcaca ggtgtgagac attttaggca ttaataaaaa aatgtggtct aattaaaacc
     9781 acatttttta ttaaaagaaa atataagtta actataattt gttagcttta tcagcattta
     9841 cccatgttcc acgagatccg atttgaacat aaataccatt acttggttga tcaattttta
     9901 atactttata actaccagtg acggtaaaat attcacccac acggagaatt tgatctccta
     9961 aaacttttcc ttggttatct gtttcatcta atggtgtggg atcaatccag tttagtggag
    10021 ttgggtctcc tccggctaat tctttattaa cgatcaaatt attaacaagc tgatctacac
    10081 gaaaaacgcc agggaaggta acagtatcac cgaccttaat ggaaggtttt gtattgtcat
    10141 tttgaaccac agactgtgcg ggctctttaa tgggaatata gcgtcggttt ccagaaaaac
    10201 tgaggtagct aagccatgta taacctccag cagtcacgac tttatcgtaa taaacagatt
    10261 gacctgcttc atagtaagca agatcagggc tatcgatact ggtttgtcct ttgactggta
    10321 atctggttgt aaagtgataa gttccagagg ggtcaaatga agcttgagaa atgtgtttta
    10381 gttgtcttgg gtaggaatga cttgtctgag atgataagtc tttaaaatgg atataaccac
    10441 ttacctgaga ttttggaatt tgacgcttat ggtatctttc agggccttgt ccagcgttgt
    10501 aattatactc ttcgatagtg acagtgtctc cacggatatc agctacccat gctacatgac
    10561 cgtaagcagc atttgactga taagcgtttt tatcaaacca agcgatagcc cctatgcttg
    10621 gtgtcttatt cacaggataa ccctgatttt tcgcgatatg tccccacgtg caggcattac
    10681 cgtagccttt aggtaactga aaaccattag cagagcttaa acgaaaagct gcaaaagaag
    10741 tgcattggcg gatatacatg ttccacgaat cgattccatt gccttttttc cacttactcg
    10801 gatagttatc gcctaaaaca gctgcatgaa caagattttc ctgttgcgaa ataagtgtag
    10861 atggcatagt aggtactaga ccattaaaac ctaaaaggat tactcctgag accaaaaaac
    10921 gatgaaattt tttcattaat tacctcctgt aacttattat tcgaaagcaa gaaacaaaaa
    10981 atgttatttt tagatgatta ttttgaaaat tggctttact tgatattaaa taactgtttg
    11041 attggctaat agagtgttcc ttatttcaag aattgtggtc tactatcaca tttttacaat
    11101 gtttcaatta ttgataacta atacattatg taaaaaagcg aacgtttatg atataatatc
    11161 taattataat acgaaagagg tggatgtttt gaaattactt gttgttggtt caggtggtcg
    11221 tgaacatgcg attgctaaga agttgttagc gtctaagggt gtggatcagg tttttgtggc
    11281 acctggtaat gatggtatga ccttggatgg tctggacttg gtgaatatag tagtttccga
    11341 acattccagg ttgattgcct ttgctaagga gaatgagatt tcttgggcct ttattggtcc
    11401 tgatgatgcg ctagcagctg gtatcgttga tgatttcaac agtgctggac tcagagcttt
    11461 cggtccaaca aaggcagcag cggagctaga gtggtcaaaa gactttgcca aggaaatcat
    11521 ggtcaaatac aatgtcccaa cagcagccta tggcacattt tcagactttg aaaaagccaa
    11581 agcctacatc gaagagcagg gcgtacctat cgtggtcaag gctgatggct tggcgctagg
    11641 taagggtgtg gtcgtggctg aaaccgttga gcaggcggta gaggcggcgc aagagatgct
    11701 tctggacaat aagtttggcg attcaggagc gcgtgtggtt atcgaggaat tcttggatgg
    11761 cgaggagttt tccctctttg cctttgttaa tggtgataag ttctacatca tgccgacagc
    11821 tcaggatcac aagcgtgcct ttgacggaga caaggggcca aacactggtg gtatgggtgc
    11881 ctatgcgcca gttcctcatc tacctcagag cgtggtagac acagcggttg agacgatcgt
    11941 taggcctgtc cttgagggca tggttgccga agggcgtcct tatctaggtg tcctctatgt
    12001 ggggcttatc ctgacagctg atggacctaa ggttatcgag ttcaactcac gtttcggtga
    12061 ccctgaaact cagattatcc tccctcgcct gacttccgat ttcgctcaga atattgacga
    12121 tatcatgatg ggcattgagc cttacatcac ttggcagaag gacggtgtga ctttgggtgt
    12181 tgtcgttgcc tcagaaggct atccactcga ttatgagaaa ggtgtgccac tgcctgaaaa
    12241 gaccgacggc gatatcatca cctactatgc cggagctaag tttgtggaaa atagcgagct
    12301 acttctctca aacggaggac gtgtctatat gcttgtcacc acagaagaca gcgtcaaagc
    12361 agggcaggac aaaatctata cccagctagc ccaacaagac acaacaggtc tcttctaccg
    12421 aaatgacatc ggaagcaaag ctataagaga ataagactaa ccattcaaat attagcgtca
    12481 gcaatcaacg accgaaggtc gctccaaaaa gaaagaagaa aggaactgaa cacgggacta
    12541 atttcctagg aaaaaaataa aactacctgg acacaagcgt catcgttagt tttctgcgtc
    12601 gtaggcgtct gatgctaaag cacctagtcg ccctgacgtg ggttcgtctt cgaaatcaaa
    12661 gatttcggac ttaccgcata tttttctacg gaaattttcg acaagtcgaa acgccccttt
    12721 gtatcttaat tatgaaaact ccaattattt ctattatcat gggctccaaa tctgactggg
    12781 caaccatgca aaaaacggct gaagttctag acaactttgg cattgcttac gagaagaaag
    12841 tcgtctctgc ccaccgtacg ccagacctca tgttcaagca tgctgaggaa gcacgtggtc
    12901 gtggcatcaa aatcatcatc gcaggagcag gtggggcagc tcacttgcct ggtatggtgg
    12961 cagctaaaac aaccctgcct gttatcggtg tgcctgtcaa atcacgtgcc ctttcaggtt
    13021 tggattcact ctattcgatt gtgcagatgc ctggcggtgt gcctgtggca accatggcta
    13081 tcggagaagc gggagcgact aacgctgccc tgacagccct ccgtattctc tccatcgagg
    13141 atcaaaatct ggctgatgcg ctagctcatt tccatgagga acaaggaaaa atcgcagagg
    13201 agtcaagtgg tgaactcatt taagaccatt gggattatcg gtggtggtca gctggggcag
    13261 atgatggcca ttgcggctat ctatatgggc tacaaggtca tcacgctgga tcctgctagc
    13321 gactgccctg cctcccgcgt tagcgaggta attgtggcgc cttacgatga tgttgaggct
    13381 ttgggacaat tggctgcgcg ttgcgatgta ttgacttatg agtttgagaa tattgatgcg
    13441 gacggtttgg atgccgttgt gtcagcttgt cagctaccgc aggggaccga tctgctccgc
    13501 atttcccaaa accgtatctt tgaaaaagac tttctggcaa ataaggctgg tgtgactgtt
    13561 gctccctata aggtggtgac gtctagcctt gacctagggg gacttgattt taccaagacc
    13621 tatgtcctca agacagcgac aggtggttat gacggtcatg ggcaaaaggt tatccgctca
    13681 gcagaagatt tgccagaggc gcagcaatta gctaactcag ctcagtgtgt cttggaagag
    13741 tttgtcaact ttgaccttga aatctcagtc atcgtgtctg gaaatggaga ggatgtgacg
    13801 gtctttcccg ttcaggaaaa tatccactgc aacaatatcc tgtcaaaaac tatcgtgcca
    13861 gctcgtatct cagatcaact ggctgataag gctaagaaaa tggcggtgca gattgccaag
    13921 aaactccagc tgtcaggaac tctctgtgtg gaaatgtttg cgaccgcaga tgatatcatt
    13981 gtcaatgaaa ttgccccacg tccccacaac tcagggcact actcaatcga ggcttgcgac
    14041 ttttcacagt ttgacaccca cattttgggc gtgctaggag cgccgctccc aaccatccac
    14101 ctccatgctc cagccgtcat gctcaatgtc ctcggacaac acgtccagca ggcaattgac
    14161 tatgttgccc aaaaccctag cgcccacctc cacatgtatg gtaaactaga agcgaaacat
    14221 aaccgcaaaa tgggacatgt gacggtgttt agtgatttgc ctgatgaggt ggaggagttt
    14281 taggatgtat ctaaagtata tatttaaaat aaaggatagg aatttagtat cggattatga
    14341 atctttagtt cgaaatttga caatcaatct tcaaaaacta gttattaaag atagaactgc
    14401 attaataggg gataaacaac ttccaattac gatatattat cgtggggaga atgaaaagtt
    14461 tcctacggga atagtaaaag ttgaatcaga ctcagttgaa ggattagagt tatttgataa
    14521 aacgataaag gaaatagttg ggaatgaaag tagatttgga aagttcacat gtatatacga
    14581 tggaataagt acatattatt caacagaaat ttattctgaa cttcatgaaa ttgagcgtcg
    14641 aacacaagag tttttaaggg aagcattttt tctgagcgat aaaagtgggg aattgaaaga
    14701 atatcaggca actatcaaaa aaatggatag tagtgatttc tcattcagca aattaattaa
    14761 tgaaattttt aaagcaagcg atataactga tacatttatt gaccatgtta gagcgtgtgt
    14821 tgaatttgga acagttccaa atggagattt attaccaaaa agtttttggg atagtttaga
    14881 tgactcttta ctagatgata aagagcaagg tttagagatt aataatttat taaatgagat
    14941 tcgttcaaca agaaatacaa tagctcactg taaagagttt aaaaagaagg attatattaa
    15001 ttgtatagaa caagttaaaa aattaaagca agcattggat aaaataatag cctctataga
    15061 gtctacagat atttctaaaa tgtcacgaga agtgtcacgc ataaataact ccttacaagc
    15121 cgataatgac tacatcaaac aaaaatattt tatagaatat gatatttttg aaaaggatat
//
LOCUS       DATWVB010000038        14692 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.038, whole genome shotgun sequence.
ACCESSION   DATWVB010000038 DATWVB010000000
VERSION     DATWVB010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14692
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.038"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(80..841)
                     /locus_tag="VCX65_001397"
     CDS             complement(80..841)
                     /locus_tag="VCX65_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP5053857.1"
                     /translation="MTKEKMMSFMTIASIALLGSGVVCANDVADPVAGTTDAVVVPVS
                     PQPTTPIEHTGTDTTNKIVDSTKPSEDKVADSTDQLIPPVKSDLETSEDKVTDPTETK
                     PSKEKTEEPVKSNDSEVIPEQPKSEEVKKAEENTGASTTETPKPVTKPVIETPIVTNT
                     GYTVLGTQDGNVWVQTETGNVLKPAIAIGAVKQKDGTVALKTRDGKLEVLPSTGETKT
                     ILAILGGLAILGAIWVGWKENIKKYLTFLKKKSKK"
     gene            complement(866..1423)
                     /locus_tag="VCX65_001398"
     CDS             complement(866..1423)
                     /locus_tag="VCX65_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053858.1"
                     /translation="MKIRKVIIVMLAVALSLGFYRLYHRQKPSQLIEANQEILVKPIT
                     PNKSKIKVKRNVAKEAKATLEMPEERVNEKEAKQVKSAIVIPIDYLASISSQDDIKVT
                     YDNKLSITNPAMAASIKTMLLAGYHFDLDSLTVYQSNSDNVYQFTILLVTHQQDQLSL
                     VGNYVTGTGQFEFVSLHGTPKNVMF"
     gene            complement(1423..2775)
                     /locus_tag="VCX65_001399"
     CDS             complement(1423..2775)
                     /locus_tag="VCX65_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP5053859.1"
                     /translation="MSIPFFIVVIVTIIFSSSQGDCQVTPDLSTQFVTSSDSASQTDW
                     TKKGSIANVTAGKVFHAWVSKGLSGASAAGIVGWVNSEGGFAMIGRAEGHYGNDLRTN
                     SIAFGVKPIGLSYYTTEAGGGIYQFTPYTKYAPLGDPKWENADAMNEFVAKAILAGDW
                     NASMDLTGGNHTFKQMAQMTDPKQATLVWQAYERGSTAHINPFQKQADAQKAYELFGG
                     VKYSYNEIVFHKSFDIFGPLKPGEGESKEVVLSLCESGSYSKGAFGKDRTGKVNYTSY
                     NAWRPEQLPADLKPYALDPRSVGLNYRQAVGWYAIASTGGQCTDLSASLMYALWSKNG
                     SHPTQKAGNGNMVVANWVRTFGGSSDKSPTSGAVFSSAGTSSAGHTGVVSHVFENGDI
                     LIVEQNYASYSGDDGGFGKYSWNYRYVTTAELKNEGYTFYNPAKLGYQIMKSVGTVGK
                     "
     gene            2916..3059
                     /locus_tag="VCX65_001400"
     CDS             2916..3059
                     /locus_tag="VCX65_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEP5053860.1"
                     /translation="MGNSSKSNRKEELDLSTFEVLTLMFIAGNFVIALVKLVLELVKS
                     TKK"
     gene            complement(3227..3796)
                     /locus_tag="VCX65_001401"
     CDS             complement(3227..3796)
                     /locus_tag="VCX65_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053861.1"
                     /translation="MGKHSPMNFSKPSQMTESIDHDVHYDLPGVNEEMESPFQSESDY
                     QSQNSSIIVETPEMDDMIYQSSQKKNISIGNNYSSDKKSLENSFDSPIIPERSEPETD
                     AKERFNPQAEYQRLKAKRQKPLGNRKKSKLEAELGQFTDDASYYKAHGGTAFKRGFNA
                     SKSKELRLKQNLERKATILAELDKLRGHV"
     gene            complement(4370..5542)
                     /locus_tag="VCX65_001402"
                     /pseudo
     CDS             complement(4370..5542)
                     /locus_tag="VCX65_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5557..8058)
                     /locus_tag="VCX65_001403"
     CDS             complement(5557..8058)
                     /locus_tag="VCX65_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEP5053862.1"
                     /translation="MVKKLEYPINSIHSNLALRKDKVVIAYYRIPNTPITITDSDKKD
                     SHKDKVAQVIKKLAKYKHFDISLVPKDYLLEEKMSDFIGDLADDVKDLGIDTLSYTVD
                     TLTAEIEIPYQFDWVIGVNLGRDTMSATLKELAVKQLDLIADNVASLLGYTVELDKEW
                     YKEYQDEELLLYGLLSSLKAKRLSEEDLFYYQRMQYLRYIPHAKNEVIANRTLLNVTD
                     TLVKPLSGGFLKLESPYGSSFITILPVGKFNTIFNGFHLGELVQRMSFPVELRFKAEF
                     INKTKLSGTMGRSNTRYDQIMKEAYSTNTVQQDDILMGSYSLKDLMKKVGNKEEIIEY
                     GCFLVVSGSSIKQLRQRRHAVLSYFADMQVNVHEASHDTPYLFQTLLYGQNLQKTTRK
                     WNHLVTSRGFSEMMLFTNTQSGNRIGWYIGRVDNRLSAWDNIGEAIMGSKNLVLFNAT
                     VANKEDVAGKVTKNPHIIITGATGQGKSYLAQMIFLHTAQQNVRVLYIDPKRELRKHY
                     LQVVSDPEYAKQFPLRKHQIEQINFVTLDSAMKENHGVLDPIVILDKEDASSTAKNIL
                     LYLLRNATEVKIVQTTALTEAISEVISRRENGEVVGFNQVIETLCQSDNQDIVDVGHY
                     FKAIIKNSILELAFSDGNVKGLSYEERVTVLEVADLSLPKDGSDHISDHESNSIALMF
                     ALGAFCKHFGERTNEETVEIFDEAWILMQSSEGKAVIKSMRRVGRSKYNVLMLVSQSV
                     HDAENDDDTTGFGTIFAFYEKSEREAILTHVGLEVNEKNLEWIDNMISGQCLYYDVYG
                     NLNMMSVHNIHPDIDPLLKPMKQSVSSHLENKYAS"
     gene            complement(8079..8489)
                     /locus_tag="VCX65_001404"
     CDS             complement(8079..8489)
                     /locus_tag="VCX65_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP5053863.1"
                     /translation="MEEEKYFDYSRGLNAPYWIQEIKTSKGKLLWYFSTPMQLSFFIV
                     FFLILVLMLTVFSAPMQLLNQLTHSISLLLYWFVPYRLSKFYTEYEPQGKKMHTYLWD
                     YLVYLIDYGFNKKAIYQGERVEVLEEIVFEKTNI"
     gene            complement(8492..8761)
                     /locus_tag="VCX65_001405"
     CDS             complement(8492..8761)
                     /locus_tag="VCX65_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053864.1"
                     /translation="MKVSKVAQVVLTGGGPNVSGLKQFFQGDGIYLISVICAFLVIKN
                     WKNADWLKVGSVLSIYAIVVSLFKGQEILAFLGGMLRWFGIETGL"
     gene            complement(8780..9730)
                     /locus_tag="VCX65_001406"
     CDS             complement(8780..9730)
                     /locus_tag="VCX65_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP5053865.1"
                     /translation="MDYLVKIKKFLLRYTKKEKGGKQPKPKEVKQKTANIIVYGILGL
                     LFIVGFFGSLRAIGLSNQVNSLKATVLSSKQQNGKDTKEILDIPRVQYYMNNFVYTYI
                     NYSDDTATKRKEELDNYYSFSTANLVDDVKKERKLQTQRLVSVEQEEDYHIALMRIGY
                     EVDSKSYQMTLAIPFRMANGLLAIVSPPYTLAEDLFQGKSKSFERKTVDQVKSLPKQE
                     MLSIQKFLPVFFDKYALSNEIDLKLLMKHPELMGGNYRVKSLDANNARYYQDKSNQVV
                     QLMVTFEDMVTGGTRSENFTLYLIKSDNGWYVDKLYHYFK"
     gene            complement(9731..10210)
                     /locus_tag="VCX65_001407"
     CDS             complement(9731..10210)
                     /locus_tag="VCX65_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053866.1"
                     /translation="MIAIIRTHEKGRSQFLCELDIMQFTENQVRDHMIERGIKDDAFF
                     ICGFSDWNVDRIMSLSEVYLLKRCIVGLYDGDDYIVQYLLKKGLSVPAIVTKFYVFLS
                     KDEKEAMGYVLKNVSFDSLIDFWQRSVTWANALNAYIQSGILLNTSKGFYVLKTEGG"
     gene            complement(10218..10699)
                     /locus_tag="VCX65_001408"
                     /pseudo
     CDS             complement(10218..10699)
                     /locus_tag="VCX65_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000383283.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
     gene            complement(10752..11024)
                     /locus_tag="VCX65_001409"
     CDS             complement(10752..11024)
                     /locus_tag="VCX65_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053867.1"
                     /translation="MSNTRSEADKKLLVVTQELSELLISHQYDQSWEKAGELNSLLKK
                     REELTLPGYMVDMIQQHLKSYYYQNNMINKAHKSMSAIGHKLQEFH"
     gene            complement(11157..11362)
                     /locus_tag="VCX65_001410"
                     /pseudo
     CDS             complement(11157..11362)
                     /locus_tag="VCX65_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057932.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(11413..11790)
                     /locus_tag="VCX65_001411"
     CDS             complement(11413..11790)
                     /locus_tag="VCX65_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053868.1"
                     /translation="MFLENEFNYFISTRNNLELVIDSLVLMIPDREFYYPEIQTGELR
                     DYQIDIYDLIKIGYVGVYEIQKDYEDKLRELADFKRKLLKFGLLMQPLEKQKEIVIRL
                     AAKYHLEKRILMKKEMFRDEEVD"
     gene            complement(11791..13032)
                     /locus_tag="VCX65_001412"
     CDS             complement(11791..13032)
                     /locus_tag="VCX65_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEP5053869.1"
                     /translation="MNPMYLKKFRKKSGLKQKEFAKCIGISQAMLSQYESGKKKLSLE
                     KFQEMKTHFGYLTDNDSSRLQVTIDYVRITLKSVRDLEFFCRNFLHCRFKEFSSVESK
                     LMNYNHIWKRGDIWIFDYADKHDTGNYQITLQLSGQGCRQLELLMEQENFAWLDWLIY
                     LRRSYRDEMNVTRFDLAIDELYLGKDRENEHFLLSDMIAKYYHHELAFESLRTWNYIG
                     GGALNFNDMEEIEQNRQGISLYFGSRQSEMYFNFYEKRYELAKLEGISVEESLEIFEI
                     WNRYEIRLSQSKANAVVDEFISGIPLGEIARGLINSKIQVYDGKNKYGAFMADQKWQM
                     MFGGVEPLTFVTRPESYNIERTIRWLIHQVSDSLAMVSEYDSMIDGDNLQMIINSGEV
                     NERGEKILETIRYNLGLDKGA"
     gene            complement(13344..>14692)
                     /locus_tag="VCX65_001413"
     CDS             complement(13344..>14692)
                     /locus_tag="VCX65_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEP5053870.1"
                     /translation="KQGKFDLSVSFEMAGNKFQKRFKDIGGELEDTFFMDFMEKTDDP
                     RFKIYKLAYSAFLARITVNDVVWEKDKGIKLMNGYYWDFINDPHLLVAGGTGGGKTVL
                     LRSILKCLATIGVADICDPKRADFVTMADLPAFRGRIVFEKVDIIAKFENAITIMYAR
                     YDFIRKEMKRLGHKDMGKFYDYGLEPYFFICDEYNALMSSLSYQERDIVENAFTQYIL
                     LGRQVGCNAIIAMQKPSADDLPTKIRSNMMHHISVGRLDDGGYMMLFGDENRNKEFRY
                     IKFLSGHRVYGRGYSAVFGEVAREFYAPLLTKKFSFYDEFAKISRHDNPFDPLENTLV
                     SKDIISDESLRKFVEKTSDNELPKGSIGFDFEEEMEEINHMSIGDLAKKTGFSFGKIK
                     NLIDMIEKDGYMTFNREDERVVLTDSDAVILNSLLTQKDKFDGSWKELLLNYFKGE"
BASE COUNT         4695 a         3085 c         2003 g         4909 t
ORIGIN      
        1 ctatgaaata atatactagt cttttcaatt tcgctccttt caacaaaact aaagccatga
       61 aattaatcat ggctttatct tattttttac ttttcttttt caaaaacgtt aaatactttt
      121 tgatattttc tttccaacct acccagatag ctcctaaaat agctaaacct cccaaaatgg
      181 ctaagattgt tttagtctct ccagttgatg gtaagacttc taacttccca tctcttgttt
      241 ttaaggcaac tgtaccatct ttttgcttta cagcaccaat tgctatcgca ggtttcagta
      301 cattaccagt ttctgtttga acccaaacat tgccatcttg cgttcccaaa accgtgtagc
      361 ctgtattcgt aacaattggt gtctcaataa caggtttcgt cacaggttta ggagtttcag
      421 ttgtactagc acctgtattt tcttcagctt ttttcacctc ttctgactta ggttgttctg
      481 gaatcacttc tgaatcattg gacttaacag gctcttccgt cttctctttg cttggcttag
      541 tctccgttgg atctgttact ttatcctcgc ttgtttctaa atctgattta actggaggga
      601 ttagctgatc agtactatct gccaccttgt cctcgcttgg cttagtcgag tcaacaattt
      661 tattggtagt atctgttcct gtatgctcaa tcggtgtcgt tggttgaggt gagactggta
      721 ccaccactgc atccgttgtt cctgctactg gatctgctac atcattagca caaaccaccc
      781 cacttccaag caaagcaata cttgcaatcg tcataaaact catcattttt tcttttgtca
      841 tcttattttt cctcttttcg tttaattaaa acatgacatt ttttggagtg ccatgtaaac
      901 tcacaaattc aaactgaccc gtaccagtaa cataattacc aacaagactt aattgatctt
      961 gctgatgagt cactaataaa atcgtaaatt gatacacatt atcagaattg ctctgataaa
     1021 ccgtcaagct atctaaatca aagtgatacc ctgctaaaag catcgtttta atgcttgctg
     1081 ccattgctgg attagtaatg gacaacttat tatcataagt aaccttaata tcatcttgac
     1141 ttgatatact agctaaataa tcaatcggta ttacaatagc tgatttcacc tgtttagctt
     1201 ctttttcgtt aacacgctcc tcaggcatct ctaaagtggc cttggcttct ttggcaacat
     1261 ttctcttaac cttaatttta cttttattcg gtgtaattgg ttttacaagt atttcttgat
     1321 tagcttctat taactgagat ggcttttgac gatgatacaa ccgataaaat cctaatgaaa
     1381 gagctactgc cagcataaca ataataactt ttcttatctt cattatttac ctaccgttcc
     1441 tactgatttc ataatctgat aaccgagttt cgcaggattg taaaaagtat atccttcatt
     1501 ttttaattct gcagtagtga catagcgata gttccaagag tatttcccaa agccaccatc
     1561 atcacccgaa taagatgcat aattttgttc cacaattaaa atatccccat tttcaaaaac
     1621 atggctgaca acacctgtat ggccagcaga actagtccct gcagaggaaa atacagctcc
     1681 tgaagttggt gatttatcag atgaaccgcc aaaagtccta acccaattag caacaaccat
     1741 attaccatta cctgcctttt gtgttggatg gctaccattt tttgaccaca aagcatacat
     1801 caaactcgca gaaagatcgg tacattgacc ccctgtcgaa gcaatcgcat accagccaac
     1861 cgcttgtcga taattcaagc caactgatct gggatcgagc gcataaggtt ttaaatctgc
     1921 aggcaattgt tctggtcgcc aagcattgta ggaagtatag ttgactttgc ctgtacgatc
     1981 tttcccaaaa gcccccttag agtaagaacc tgattcgcat aatgataaaa cgacttcttt
     2041 tgattcccct tcccccggct ttagtggacc aaaaatgtca aaagatttat gaaatactat
     2101 ttcattataa ctatatttaa ctccaccgaa taactcatac gctttttgag catctgcttg
     2161 cttttgaaat ggattaatat gggcagtact accacgttca taagcttgcc aaactagcgt
     2221 agcctgtttc ggatcggtca tctgggccat ttgcttaaag gtatgatttc ctcctgtcaa
     2281 atccattgaa gcattccaat caccagctag aatggctttt gcaacaaatt cgttcatggc
     2341 atccgcattc tcccacttag gatcacctaa aggggcatat ttggtataag gggtaaattg
     2401 ataaatacct ccacctgctt ctgtcgtata gtaactcaaa ccaattggtt tcactccaaa
     2461 agctatagaa ttagttcgta aatcattacc ataatgtcct tctgctcgac ctatcatggc
     2521 aaaaccacct tcggaattaa cccaacctac aattcctgcg gcagaagcgc ctgacaagcc
     2581 tttcgatacc caagcgtgaa agactttacc tgctgtgaca ttcgcaattg agcctttctt
     2641 tgtccaatcg gtttgtgaag cagaatcact tgaggtaaca aattgtgttg ataaatcagg
     2701 agttacttga caatcacctt gactgctgct aaatatgatc gtaacgataa ctacaataaa
     2761 aaaaggaatg ctcataagca ctcctagaca tccaagtttc ttcttgataa cattccctcc
     2821 ttcttaaact ggtcagacag agatacggta tgttataata aaaaggcaga aaagttaaga
     2881 cggtggctct tatttctgaa aggtaggtgg tgcccatggg caattcatca aaatccaaca
     2941 gaaaggagga gctagatttg tctacctttg aggtcttaac actcatgttt atagcaggta
     3001 acttcgttat cgctctcgtg aagttagtcc ttgaactggt aaaatcgaca aaaaaataac
     3061 cgtctcaact ttggcgagtt aacggttatt ttttaacggt tattttctgc caccgtctta
     3121 aacggttctg cattgggtag ttgtttccgc aactgccctt ttctattttc attataactc
     3181 ttatctccaa attaagcaac tatttgataa catcacaata cttcctttaa acatgtcctc
     3241 taagtttatc taattcagct aaaatagtcg cctttctttc taaattttgt tttaaccgta
     3301 actcttttga tttactggcg ttaaatcctc ttttaaaggc agtccctcca tgtgctttat
     3361 aatagctggc atcatcagta aactgaccta attctgcttc taatttagat tttttccgat
     3421 ttcctaaagg tttttgtcgc ttagctttta gacgttgata ttctgcttga ggattaaatc
     3481 tctctttagc gtccgtttct ggttcagacc tttcaggaat aattggagaa tcaaatgaat
     3541 tttccaaaga ttttttatca gaggaataat tatttccaat agaaatattt ttcttctgac
     3601 tgctttgata aatcatatca tccatttctg gagtttcaac gataattgaa gagttttgag
     3661 attgataatc actttctgac tgaaatggac tttccatctc ctcattaaca cctggtaaat
     3721 cataatgaac atcatgatca attgattcag tcatctgact tggtttagaa aaattcattg
     3781 gggaatgttt acccaagggt tctgaattat ctaatgaagc tccaaaagat tggctgtata
     3841 agttgtctct ttcaaaatca cttacttgag agagattgta atcagaagaa aagttactct
     3901 cttgattatc gaaaacacct tgttctgctt gatgtccaga ggtaggatta ccattatcag
     3961 aaacatgcgg gacactattt gtggaaaatt cttgatctcc tgcaaaatct cctaattctg
     4021 aaaactgatg gtcgaaatta gtttcattag aaaggtcact ataattagaa gtgtcatctc
     4081 ctttgaaacg gtttttaatg gcactaagat tatccttagc atgtacaagg ctaccaacac
     4141 cataaccagc tcccatcatc gcaagattag aaatatcatg cgccttatca tagatatttt
     4201 ggggtgtaac tcctaaacta ttcgcttttt gagcaaccat atttcctgct tgtgtgactg
     4261 cttgtgcagc gtctgctcct acaattaaac ttaatacctt ttctttatgt ttccaaattt
     4321 gccaaaaaat aaccccctga acaacaatag taataaacaa cataaataaa atagattgtc
     4381 ccttaaggtt actgctgctt aacaaatgat tgtctgtaaa tcgagactta ataaatgtcg
     4441 caatcaatga ctgtatataa aagactatta aagttaaaaa acctgttaga gctggaaagg
     4501 aaacacctcc aagcattagc ttaagcatat taaaagcaat atgttgcatt ttaggtaaaa
     4561 aggacaccaa taaagccagt gggaataaaa acattaacaa tatgaccaca atatctgcta
     4621 aaaaagcaat taattgtatc aataataaag gtatagctaa tatcactgct tcaaaaattt
     4681 tcaaaataac ataaatagac ttgatccaaa tatagtcact aacagctgac atccacctgt
     4741 tttgttcttc tcctttcaaa gctccgtcac caagtttatt tgtatactct aatatttgtt
     4801 gactttttgg tattacaaac tgatttgact tatcatattt tcccagaatt ttgctattat
     4861 ctaactcctc ttcttttcct gatttattat tatgaaactt accatttaac tggccagtat
     4921 ttacaaaaag ataagctgta taagacgttt tcataacata attatcagct accgaagcct
     4981 catgagaaat gatttgcttc tcatcttctg gactcactac cgatagatta gttactgcat
     5041 cactaaaaga actagctacc gaatgaacca tatccaacac atagacaccg cccgaagttg
     5101 actgcaccgt cccaaagtaa ccgaacgcta ataacataac cgcaaacaaa tgaagtaatc
     5161 gtcttgaaaa atcacctttt gaaaaaataa aagctagaaa aatggaaaaa gcggataagg
     5221 caattaagag ataaagtaat gaattcgtaa aatctgcgga tttagagagg ttatcccaca
     5281 aaactttgga actatcaaac acagtctgac gataagtatt atacaagcta aagttttcaa
     5341 aaaatcgtag aataatggaa aagaaaccaa caatcaagtt aagtagaaaa aagggaaaat
     5401 taacaaaaat atctgtcaaa gttacttgta accccgtctc aagaccttct gtactttcca
     5461 tgtaagcctt taatgcaaaa atatccacat ccttgacttt ctgaaaggta gaagctatta
     5521 atccatcatc aatcttatcc atttggcctc tcctttctac gaagcgtatt tattttctaa
     5581 gtggcttgaa acagactgtt tcattggttt taataaggga tcaatatctg gatgaatgtt
     5641 atggacagac atcatattga ggttgccata aacatcataa taaaggcatt gtcctgaaat
     5701 catgttatca atccactcca ggttcttttc gttcacttcc aaaccaacat gagttaaaat
     5761 agcttcccgt tctgattttt cgtaaaaagc gaaaatagta ccaaaaccag tcgtatcgtc
     5821 atcattttcg gcatcatgta ctgattgaga cactaacatt aaaacattgt acttagaacg
     5881 accaacgcgg cgcatagact tgataacggc cttaccttct gatgactgca tcagaatcca
     5941 agcctcatca aaaatttcaa cagtttcctc attggttcgt tccccaaagt gcttacaaaa
     6001 agcacctaaa gcaaacatta aagcgattga attactttca tgatcagata tatgatctga
     6061 accatcttta ggtaacgata agtccgcaac ttctaaaact gtcacacgct cttcatatga
     6121 taatccttta acattaccat ccgaaaaagc caattccaaa atagaattct taataatagc
     6181 tttaaaataa tgtcctacat ctacaatatc ctgattatct gattgacata atgtctcaat
     6241 gacttgatta aagccaacga cttccccatt ttcacgtctt gagattactt cactaatggc
     6301 ctctgtcaaa gcagtagttt gtacaatctt aacttctgtc gcatttctta acagataaag
     6361 caatatattt ttagcagtag acgaggcatc ttctttatcc aagataacga taggatctaa
     6421 aaccccatgg ttttccttca tcgcactatc caatgtcaca aaattaattt gctcaatctg
     6481 atgttttctc agtggaaatt gtttcgcata ctcgggatca gacaccactt gtaaatagtg
     6541 tttccttaac tctctcttag gatcaatata aagcactcta acattttgtt gcgcagtatg
     6601 taaaaaaatc atctgtgcaa ggtaggactt cccctgacct gtcgcacctg taatgataat
     6661 atgaggattt ttagttactt taccagcaac atcctcctta ttcgcaaccg ttgcattaaa
     6721 caaaactaag ttcttcgagc ccataatcgc ttcaccaata ttatcccaag cagataaacg
     6781 attatcgact cgaccaatat accagccaat cctgttacct gactgggtat ttgtaaataa
     6841 catcatttca ctaaacccac gactggtcac taagtgattc catttacgtg ttgtcttctg
     6901 taaattttga ccataaagta acgtttggaa taaataaggt gtatcatgac tagcttcatg
     6961 tacattgact tgcatatccg caaagtaact taaaacagca tgcctacgtt gccttaattg
     7021 tttgatacta gacccagaaa ccaccaaaaa acaaccgtat tcaatgattt cttctttatt
     7081 tccaactttc ttcatcaagt cttttaatga atatgagccc attagaatat catcttgttg
     7141 cactgtattc gtggagtagg cttctttcat aatttgatca taacgtgtat tcgagcgtcc
     7201 cattgttcca cttaacttag ttttattaat aaattctgct ttaaatcgta actcaacagg
     7261 aaaactcatc cgctgtacga gttcacctaa gtggaaccca ttgaagatag tattaaactt
     7321 cccaactggt agaatcgtta taaatgaact accatacgga ctttctaact ttaaaaaacc
     7381 tcccgacagg ggcttaacta aagtatctgt tacgttcaac aatgttctat tggcaataac
     7441 ttcattttta gcatgtggga tatagcgtaa gtattgcatg cgttgataat aaaataaatc
     7501 ttcttcagat aatctcttag ctttcagtga tgataacaaa ccatacagca ataattcttc
     7561 atcttggtac tctttatacc actccttatc aagttccaca gtgtatccca acaaagaggc
     7621 gacattatct gcaattaaat ccaattgctt taccgcaagt tcttttagtg tagcactcat
     7681 tgtatcccta cctaaattaa caccaataac ccaatcaaat tgataaggta tttcaatctc
     7741 agctgtcaac gtgtcaacag tgtaactcaa tgtatctata cctaaatcct taacatcatc
     7801 tgccaagtca ccaataaaat cagacatttt ttcctctaaa aggtaatctt ttggtaccag
     7861 tgaaatatca aaatgcttgt atttagctaa ttttttgata acctgtgcta ccttgtcttt
     7921 atgactatct tttttatcac tatcagtaat agtgattggc gtatttggaa tccgatagta
     7981 ggcaataacc actttatctt ttcgcaaagc taaattactg tgaatgctat taattggata
     8041 ttccaacttt tttaccatct gatctccttt cttaatcttt aaatgtttgt tttctcaaat
     8101 acaatttctt ctagtacctc tactctttct ccctgataaa tagctttttt attaaaacca
     8161 taatctatta aatagacaag ataatcccaa agataagtat gcatcttttt accttgtggc
     8221 tcatactccg tataaaattt tgaaagtcga tatgggacaa accagtacag taacagagaa
     8281 atagaatgcg ttagctgatt tagcagttgc ataggagccg aaaagactgt caacatcaat
     8341 actaaaatca aaaagaaaac aataaaaaag gaaagctgca ttggtgttga gaaataccac
     8401 aataactttc cttttgacgt ttttatttct tgaatccagt aaggggcgtt taggccccta
     8461 ctgtaatcaa aatatttttc ttcttccatt tttataaacc tgtctcaata ccgaaccagc
     8521 gaagcatccc tcctaaaaag gcaagaattt cttgcccttt aaacagagaa accacaatcg
     8581 cataaattga cagtactgag ccaactttta gccaatctgc atttttccaa tttttaatca
     8641 ctaaaaaagc acagataaca ctaataagat aaatcccatc tccctgaaaa aattgtttta
     8701 gtcctgaaac attaggtcct cctcctgtta aaacaacttg agctactttt gatactttca
     8761 ttaattaaac ctcgcttttt tatttaaaat aatggtacaa cttgtcaaca taccaaccat
     8821 tatctgactt aatcagatac agcgtgaaat tctctgaccg tgtacctcct gttaccatat
     8881 cttcaaaggt aaccattaat tgcacaactt gatttgattt atcttgataa taccgagcat
     8941 tgttagcgtc taaagatttg actcgatagt ttccacccat cagttcagga tgcttcatta
     9001 gtaacttcag atctatttca ttacttaaag catacttatc aaaaaataca ggtaaaaatt
     9061 tttgtattga taacatttct tgcttcggta aactcttgac ttgatccaca gtttttcttt
     9121 caaaactttt tgatttccct tggaaaagat cctccgctaa ggtatatgga ggacttacta
     9181 ttgccaataa tccattagcc atacgaaatg ggatagccaa cgtcatctga taagatttac
     9241 tatctacctc atagcctatt ctcattaaag caatatgata atcctcttct tgttctacac
     9301 taaccagtcg ttgagtctga agcttacgct cctttttaac atcatcaaca agattagctg
     9361 ttgaaaaaga ataataatta tctaattctt ctttacgttt tgtagccgta tcatcagaat
     9421 agttgatgta agtatacaca aaattgttca tgtaatactg cactctagga atgtctaaga
     9481 tttcctttgt atcttttccg ttttgttgct tgcttgataa aaccgtagct tttaaactat
     9541 ttacttgatt tgacaaacca attgccctta atgagccaaa aaatcctaca ataaataata
     9601 atcctaaaat tccatagaca ataatattgg ctgtcttttg ttttacttcc tttggtttag
     9661 gctgctttcc tcctttttct ttctttgtat atctcaatag aaactttttt attttcacta
     9721 aataatccat ctaacctcct tctgttttta acacataaaa tcctttggat gtatttaaca
     9781 atattccact ttgtatgtaa gcgtttaaag catttgccca agttactgac cgttgccaaa
     9841 aatcaatcaa tgaatcaaat gatacatttt tcaaaacata tcccattgct tctttttcat
     9901 cttttgacaa aaagacataa aactttgtca ctatggctgg cactgacaag cctttcttta
     9961 acaaatattg aacaatgtaa tcatcgccat cataaagacc aacaatacat ctctttaaaa
    10021 ggtaaacttc cgaaagtgac ataatcctat caacattcca atcagaaaaa ccacaaatga
    10081 aaaaggcatc atccttgata cctctttcta tcatgtgatc tcttacttga ttttccgtaa
    10141 actgcatgat gtctaactca cataaaaatt gacttctacc tttttcatga gttcttataa
    10201 ttgcaatcat tatctactta ccctgatatt tcgacatatc cgtagtctga aaaaccacct
    10261 tggctttcta agtcaatatc tcgaccataa gcttcacaat caaaatagag ttccatattt
    10321 tctttaccaa caccttctga acctaattca ttaaaccagt attcgcctaa ttctcgtcta
    10381 gttgtgacat caggcagtaa acaacaatca ccaaaattaa aatcataatc tacaaagtct
    10441 gaggcagtat aacctgttac ctgatgcact gcttgaacaa gttcactatc aacattctct
    10501 accagttcaa caaattatta atcatctcaa tagaatcatg ttcttttagt aactgacaat
    10561 ccgaatctgc aataatatac tctaaatcat cttcttcacg aagccccaaa gctaacttaa
    10621 gctcactcat ttccacagga aaacaaacta acgtagctct accagttttt atatctctaa
    10681 caattgcact aacatccatt tttgacactc cttaattaaa aaaggagcaa gccattgact
    10741 tgctctcatc cttaatgaaa ttcttgtagt ttatgaccaa tcgctgacat agacttatga
    10801 gccttattaa tcatattatt ttggtagtag tatgatttca aatgttgttg aatcatgtcg
    10861 accatataac ctggtaaggt caattcttca cgttttttaa gtaagctatt taactctcca
    10921 gctttttccc atgactggtc atactgatga ctaatcagca gttctgatag ctcctgagta
    10981 accactaaca actttttatc tgcttctgaa cgtgtatttg acatttttct tttcctcttt
    11041 ttcttttttt atactcaata ccaataaatc aacatatgat agttggacac ctaattttca
    11101 tcattttccc tcataaaaaa gaacctctta aggttcatga atctaaaact aactgtttaa
    11161 gcatctgaaa tacctaataa ataatttgga gtagtattta atagtttaga tagctcaatt
    11221 agttttgaaa acttggttct cgctttccgt tctcccaatt tgaatatgct cctctattaa
    11281 taccaattct atcagcaagc tcttgttgtg ttaatttatt aagctgtcgt tgttttctta
    11341 aacgatctcc aagtttttcc atttacctta ccccttatga tttataagtt ggattttaaa
    11401 tgatcccaga aattaatcaa cttcttcatc tctaaacatt tcctttttca tcagaattct
    11461 cttttccaaa tgatatttag cagctaaacg aataactatc tctttttgct tttctaaagg
    11521 ttgcataagc aaaccaaact ttaaaagttt ccgtttaaaa tcagcaagtt cccttaactt
    11581 atcttcgtag tctttttgaa tttcataaac accaacataa ccaatcttaa tcaaatcata
    11641 aatgtctatc tgataatctc taagctcacc tgtttgaatc tcaggataat aaaattcacg
    11701 atcaggaatc attaatacca aagaatcaat gaccagctct aaattatttc tcgttgatat
    11761 aaaataatta aattcatttt ctaaaaacat ctacgccccc ttatctaaac ctagattata
    11821 tcgaatagtt tctaatattt tttcacctcg ttcattcact tcaccagaat taatgatcat
    11881 ttgtagatta tccccatcaa tcatactgtc atattcacta accatagcta gagaatcaga
    11941 tacttgatga atcaaccagc gaatagtacg ttcaatatta taagattctg gtctcgtgac
    12001 aaatgttaga ggttcaacac ctccaaacat catctgccac ttttgatcag ccataaatgc
    12061 accatactta ttttttccat cataaacttg aattttacta ttaatcaatc ctctcgcaat
    12121 ttctcctaat ggaataccag aaataaattc atctaccact gcattcgcct tagattgaga
    12181 taatcggatt tcataccgat tccatatttc aaatatttct aaagattctt caacagagat
    12241 gccctctaat ttagctaatt catacctttt ctcataaaag ttaaaataca tttcagactg
    12301 tcgactacca aaatataacg aaataccttg acgattctgt tcaatttctt ccatatcatt
    12361 aaaatttaaa gcaccaccac caatataatt ccatgttcgc aaactttcaa aagctaactc
    12421 atgatgataa tatttggcaa tcatatccga taaaagaaag tgttcatttt ctctatcctt
    12481 acccagatac aattcatcaa tagctaagtc aaaacgtgta acattcattt catctcgata
    12541 agaacgtctt aagtagatta gccaatctaa ccaagcaaaa ttttcttgtt ccataagtaa
    12601 ttctaattgt ctacatcctt gaccagatag ctgtaatgtt atttgatagt ttcctgtatc
    12661 atgtttatct gcataatcaa atatccaaat atctccacgt ttccaaatat ggttataatt
    12721 catcaactta gattcaactg atgaaaattc tttaaatcga caatgtaaaa aattccgaca
    12781 aaaaaattcc aaatctctaa cgctttttaa cgtaatcctg acatagtcaa ttgtcacttg
    12841 taatcttgaa ctatcattat cagtcaaata accaaaatgt gttttcattt cttgaaattt
    12901 ttcaagagat aattttttct taccagattc atattgagat aacatagctt gactaatacc
    12961 tatacatttt gcaaattctt tctgctttaa gcctgatttc ttcctaaatt tctttaaata
    13021 cattggattc atctattttc tccctaaata ttatcaattt ttagctattt tttgataaaa
    13081 tataacctgt ttttgctcgt tttataacct atttttgaaa cttgaaaatc cttgatacat
    13141 atggggtttc gggggtttta cttcgtagat ttttcaaatc ttacccccct attagaaatc
    13201 gggggtttta aaattgataa atccctctgt aaagccctag tgtgtgcgct gtgtccggcg
    13261 tgtccgtttc cgctacgcta cactacgcct acagctacac tagggcttta cagaaggata
    13321 tttaaaaaaa tacccttcat ctactattca cccttaaaat aattcaacaa caactctttc
    13381 caactgccat caaacttatc tttttgagtg agtaaactat tcaatataac tgcatcagaa
    13441 tcagtcaata ctactctttc atcttcacga ttaaaagtca tgtaaccatc tttttcaatc
    13501 atatcaatta aattttttat tttaccaaat gaaaaacctg ttttcttagc taaatcacca
    13561 atactcatat gattaatttc ctccatttcc tcttcaaaat caaagccaat acttccttta
    13621 ggtaactcat tgtcagacgt tttttctaca aattttctca atgattcatc tgaaataata
    13681 tccttggaaa ccaaagtatt ttcaagcgga tcaaatggat tatcatgacg tgagattttc
    13741 gcaaattcat cataaaatga aaatttctta gttagcaaag gagcataaaa ctctctcgct
    13801 acctcgccaa aaacagcaga atagccacga ccatacacac ggtgacctga tagaaattta
    13861 atatacctga actctttatt ccgattttca tccccaaaaa gcatcatata accaccatca
    13921 tcaaggcgac caacagaaat atggtgcatc atatttgacc tgatttttgt tggtaaatca
    13981 tctgcggatg gcttttgcat ggcaataatc gcattacagc ctacttgacg gccaagtaga
    14041 atatactgtg taaaggcatt ctcaacaatg tctctttcct gatacgataa cgaagacatc
    14101 aaggcattat attcatcaca aataaaaaaa tatggttcta atccgtaatc ataaaatttc
    14161 cccatatctt tatgccctaa acgtttcatt tccttacgaa taaagtcata gcgtgcatac
    14221 atgattgtaa ttgcattctc aaatttagca ataatatcta ctttttcaaa aacaattctt
    14281 cctcgaaaag caggtaaatc agccattgtc acaaaatcag ctcgcttagg atcacatata
    14341 tccgcaacgc caatagttgc aagacatttt aaaattgatc taagcaaaac agtcttaccg
    14401 ccaccagtcc cacccgcaac aagcaaatga ggatcattga taaaatccca ataataacca
    14461 ttcatcagct taatgccttt atccttttcc catacaacat cattaaccgt tatacgagcc
    14521 agaaaggcgg aataagctaa tttataaatc ttaaacctag gatcatcagt tttttccata
    14581 aaatccataa aaaaagtatc ttcaagttca cctccaatat ctttgaaacg cttttgaaat
    14641 ttgtttcctg ccatttcaaa ggagacactt aaatcaaact taccttgttt ta
//
LOCUS       DATWVB010000039        14553 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.039, whole genome shotgun sequence.
ACCESSION   DATWVB010000039 DATWVB010000000
VERSION     DATWVB010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14553
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.039"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            57..1727
                     /gene="sfbI"
                     /locus_tag="VCX65_001414"
     CDS             57..1727
                     /gene="sfbI"
                     /locus_tag="VCX65_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein SfbI"
                     /protein_id="HEP5053871.1"
                     /translation="MNNKIFLNKEAGFLAHTKRKRRFAVTLVGVFFMLLACAGAIGFG
                     QVAYAADEKTVPNFKSPDPDYPWYGYDAYTGAFLRYHDLRVNLNGSRSYQVYCFNIKK
                     NYPRPFTSSDKKWYKRLEGTAETFKVHAMAPRVGGEELTKKLRSVMYNGYPNDGNNIM
                     KGLEPSNAIEVTQYAVWYYSDKSQYEIETLWKSEAKEGKISESQVTLMREALRKLISS
                     DEDLVKQVPSNFKLSTFESSDKSYQNLLSAEFVPDDPPKPGDTSEHNPKTPELDGSPI
                     PEDPKHPDDNLEPTLPPVMLDGEEVPEVPSESLEPALPPLMPELDGEEVPEVPSESLE
                     PALPPLMPELDGQEVPEKPSVDLPIEVPRYEFNNKDQSPLAGESGETEYITEVYGNQQ
                     NPVDIDKKLPNETGFSGNMVETEDTKEPEVLMGGQSESVEFTKDTQTGMSGQTTPQVE
                     TEDTKEPGVLMGGQSESVEFTKDTQTGMSGFSETVTIVEDTRPKLVFHFDNNEPKVEE
                     NREKPTKNITPILPATGDIGNVLAFLGILILSVLSIFSLLKNKQNNKV"
     gene            2015..2863
                     /locus_tag="VCX65_001415"
     CDS             2015..2863
                     /locus_tag="VCX65_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEP5053872.1"
                     /translation="MTERLKNLGILLLFLLGTAIFLYPTLSSQWNAYRDRQLLSTYHK
                     QVTQKKPSEMEEVWQKAKAYNARLGIQPVPDAFSFRDGIHDKNYESLLQIENNDIMGY
                     VEVPSIKVTLPIYHYTTDEVLTKGAGHLVGSALPVGGDGTHTVISAHRGLPSAEMFTN
                     LNLVKRGDTFYFRVLNKVLAYKVDQILTVEPDQVTSLSGVMGKDYATLVTCTPYGVNT
                     KRLLVRGHRIAYHYKKYQQAKKAMKLVDKSRMWTEVVCAAFGVVIAIILVFMYSKMTD
                     KKVIKN"
     gene            3149..5392
                     /locus_tag="VCX65_001416"
     CDS             3149..5392
                     /locus_tag="VCX65_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus ancillary protein 1"
                     /protein_id="HEP5053873.1"
                     /translation="MNNKKLQKKQDAPRVSNRKPKQLTVTLVGVFLMLLVLIGFEGKV
                     RAAHELVEVPVPIFHNPDPQSDYQWYGYEAYTGGYPKYDLFKTYYHDLRVNLHGSKSY
                     QVYCFNVHKHYPRSSQSFDRKWYKKLDGTAENFDSLAMEPRVRKEELTKKLLAVMYNA
                     YPNDANGIMKDLEPLNAIKVTQEAVWYYSDSAQINPDESFKTEAQSNGINDQQLGLMR
                     KALKELIDPNLGSKYSNKTPSGYRLNVFESHDKTFQNLLSAEYVPDTPPKPGEEPPAK
                     TEKTSVIIRKYAEGDYSKLLEGATLRLTGEDIPDFQEKVFQSNGTGEKIELSNGTYTL
                     TETSSPDGYKIAEPIKFRVVNKKVFIVQKDGSQVENPNKEVGSPYTIEAYNDFDEFGL
                     LSTQNYAKFYYGKNYDGSSQIVYCFNANLKSPPDSEDHGATINPDFTTGDIRYSHIAG
                     SDLIKYANTARDEDPQLFLKHVKKVIENGYHKKGQAIPYNGLTEAQFRAATQLAIYYF
                     TDSVDLTKDRLKDFHGFGDMNDQTLGVAKKIVEYALSDEDSKLTNLDFFVPNNSKYQS
                     LIGTEYHPDDLVDVIRMEDKKQEVIPVIHSLTVKKTVVGELGDKTKGFQFELELKDKT
                     GQPIVDALKTNNQDLVAKDGKYSFNLKHGDTIRIEGLPTGYSYTLKETEAKDYIVTVD
                     NKVSQEAQSASENVTADKEVTFENRKDLVPPTGFTTDGGTYLWLLLLVPFGLLVWFFG
                     RKGLKND"
     gene            5385..5906
                     /gene="lepB"
                     /locus_tag="VCX65_001417"
     CDS             5385..5906
                     /gene="lepB"
                     /locus_tag="VCX65_001417"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEP5053874.1"
                     /translation="MTNYLNRLNENPLFKAFIRLVLKISIIGFLGYILFQYVFGVMIV
                     NTNQMSPAVSAGDGVLYYRLTDRYHINDVVVYEVDNTLKVGRIAAQAGDEVNFTQEGG
                     LLINGHPPEKEVPYLTYPHSSGPNFPYKVPTGTYFILNDYREERLDSRYYGALPINQI
                     KGKISTLLRVRGI"
     gene            5928..6965
                     /locus_tag="VCX65_001418"
     CDS             5928..6965
                     /locus_tag="VCX65_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QVPTGV class sortase B protein-sorting
                     domain-containing protein"
                     /protein_id="HEP5053875.1"
                     /translation="MKKNKLLLATAILATALGTASLNQNVKSETAGVSENAKLIVKKT
                     FDSYTDNEVLMPKADYTFKVEADSSATDKTKDGLEIKPGVTEGLTTEQTIAYDNSVKP
                     SDKSKTATFDFSTVKFPEVGVYRYTVSEIDSKVSGIKYDTKTWIVDVYVVNDGNGGFK
                     ARYIVSKEKGQNDKKPVVFENSFKTTSLKVEKQVTGNTGELKKDFNFTLTINPNDNFV
                     AGQVIKLEKGGIKADVKIGEPYKFALKNGEKVTLSKLPVGVTYSIIEDEADKDGYTTN
                     AKITDGTAAPVEYKLGNQQLADESADEIVVTNNRDTQVPTGVVGTLAPFAVLSIVAIG
                     GVIYITKRKKA"
     gene            6981..7706
                     /gene="srtB"
                     /locus_tag="VCX65_001419"
     CDS             6981..7706
                     /gene="srtB"
                     /locus_tag="VCX65_001419"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HEP5053876.1"
                     /translation="MMMTIVQVINKAIDTLILIFCLVVLFLAGFGLWDSYHLYQQADA
                     SNFKKFKTAQQQPKFEDLLALNEDVIGWLNIPGTHIDYPLVQGKTNLEYINKAVDGSV
                     AMSGSLFLDTRNHNNFTDDYSLIYGHHMAGNAMFGEIPKFLKKDFFNKHNKAIIETKE
                     RKKLTVTIFACLKTDAFDQLVFNPNAITNQDQQRQLVDYISKRSKQFKPVKLKHHTKF
                     VAFSTCENFSTDNRVIVVGTIQE"
     gene            7723..8310
                     /locus_tag="VCX65_001420"
     CDS             7723..8310
                     /locus_tag="VCX65_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HEP5053877.1"
                     /translation="MRKYWKMLFSVVMILTMLAFNQTVLAKDSTVQTSISVENVLERA
                     GDSTPFSIALESIDAMKTIEEITIAGSGKASFSPLTFTTVGQYTYRVYQKPSQNKDYQ
                     ADTTVFDVLVYVTYDEDETLAAKVISRRAGDEEKSAITFKPKRLVKPIPPRQPDIPKT
                     PLPLAGEVKSLLGILSIVLLGLLVLLYVKKLKSRL"
     gene            complement(8469..9674)
                     /locus_tag="VCX65_001421"
     CDS             complement(8469..9674)
                     /locus_tag="VCX65_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEP5053878.1"
                     /translation="MVIFDLKYVQTLHSLSQLPISVMSQDKALIQVYGNDDYLLCYYQ
                     FLKHLAIPQAAQDVIFYEGLFEESFMIFPLCHYIIAIGPFYPYSLNKDYQEQLANNFL
                     KHSSHRSKEELLSYMALVPHFPINNVRNLLIAIDAFFDTQFETTCQQTIHQLLQHSKQ
                     MTADPDIIHRLKHISKASSQLPPVLEHLNHIMDLVKLGNPQLLKQEINRIPLSSITSS
                     SISALRAEKNLTVIYLTRLLEFSFVENTDVAKHYSLVKYYMALNEEASDLLKVLRIRC
                     AAIIHFSESLTNKSISDKRQMYNSVLHYVDSHLYSKLKVSDIAKRLYVSESHLRSVFK
                     KYSNVSLQHYILSTKIKEAQLLLKRGIPVGEVAKSLYFYDTTHFHKIFKKYTGISSKD
                     YLAKYRDNI"
     gene            10059..13553
                     /locus_tag="VCX65_001422"
     CDS             10059..13553
                     /locus_tag="VCX65_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEP5053879.1"
                     /translation="MTQKNSYKLSFLLSLTGFILGLLLVFIGLSGVSVGHAETRNGAN
                     KQGSFEIKKVDQNNKPLSGATFSLTPKDGKGKPVQTFTSSEEGIIDAQNLQPGTYTLK
                     EDKAPDGYDKTSRTWTVTVYENGYTKLVENPYNGEIISKAGSKDVSSSLQLEKSTMSV
                     FSKYGGTEVTSGAADFYRNHAAYFKMSFELKQKDKSETINPGDTFVLQLDKRLNPKGI
                     SQDIPKIIYDSENSPLAIGKYDAKTHQLTYTFTNYIAGLDKVQLSAELSLFLENKVVL
                     ENQTISDFKSTIGDQEIKYGGTVNVLYGNASGQDNNYVTNGLSNVGGSIESYNTQTGD
                     FTWYVYVNPNRTNIPYATMNLWGFGRLVKSNNSTSKSEDSATSSAQLEKVEIYEVKED
                     YTLPTSYGVDLTKLNLRKDLEAKLPQDSTQNSNKRLRIDFGDKLQNKAFVVKITGKTD
                     QSGKPLVVQSNLASFNNETAVTYGNPVNNVYFQNEIALSPSKGSGSGTSEFTKPSITV
                     ANLKRVAQLRFKKMSTDNVPLPEAAFELRSSNGNSQKVEAKSNTQGEVHFKDLTSGTY
                     DLYEKQAPKGYQQVTEKLATVTVDTTKPAEEMVTWGSPHSSVKVEDSKEVTIVNHKET
                     LTFSGKKIWENDRPDQRPAKIQVQLLQNGQKMSDKVQEVTKDNDWSYHFKDLPKYDDR
                     NQEYKYSVEEVKVPDGYKVSYLGNDIFNTRETEFVFEQNNFNLEFGNAEIKGQSGSKI
                     IDEDTLTSFKGKKIWKNDTAENRPQAIQVQLYADGVAVEGQTKFISGSGNEWSFEFKN
                     LKKYNGTGNDIIYSVREVTVPTGYDVTYSANDIINTKREVITQQGPKLEIEETLPLES
                     GASGGTTTVEDSRPVDTLSGLSSEQGQSGDMTIEEDSATHIKFSKRDIDGKELAGATM
                     ELRDSSGKTISTWISDGQVKDFYLMPGKYTFVETAAPDGYEIATAITFTVNEQGQVTV
                     NGKATKGDAHIVMVDAYKPTKGSGQVIDIEEKLPDEQGHSGSTTEIEDSKSSDLIIGG
                     QGEVVDTTEDTQSGMTGHSGSTTEIEDSKSSDVIIGGQGQVVETTEDTQTGMHGDSGC
                     KTEVEDTKLVQSFHFDNKESESNSEIPKKDKPKSNTSLPATGEKQHNMFFWMVTSCSL
                     ISSVFVISLKTKKRLSSC"
     gene            complement(13819..14484)
                     /locus_tag="VCX65_001423"
                     /pseudo
     CDS             complement(13819..14484)
                     /locus_tag="VCX65_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4972 a         2379 c         2929 g         4273 t
ORIGIN      
        1 ttgtctttct tgacaataac gtggtaagct catatatgtt tttgagagga gagaaaatga
       61 ataacaaaat atttttgaat aaagaagccg gttttttggc acacacaaaa agaaaaaggc
      121 gatttgctgt cactttagtg ggagtctttt ttatgctttt ggcatgcgcg ggtgctatcg
      181 gttttggtca agtagcctat gctgcggatg agaagactgt gccgaatttt aaaagcccag
      241 atccagatta tccctggtat ggttatgatg cttatactgg agcgttttta agatatcatg
      301 atcttagagt caatttaaac ggaagtcgga gctaccaagt ttattgtttt aatattaaaa
      361 aaaactatcc tcgacctttt acgagtagtg ataaaaaatg gtataaaaga ttagagggaa
      421 ctgctgaaac ttttaaagtt catgctatgg ctcccagagt agggggagag gaactaacta
      481 aaaaattacg gagcgttatg tataacggct accctaatga cggcaataat attatgaaag
      541 gtttggagcc ttcaaatgct atagaagtaa cacaatacgc agtttggtac tattcagata
      601 agtcacagta tgaaattgag acattatgga agtctgaagc gaaagaaggt aagattagtg
      661 agtcacaagt tactttaatg cgtgaagccc tgaggaaact aatttcctct gatgaagatt
      721 tggttaaaca agttccatcg aactttaaac ttagtacttt tgagtcttct gataagtcct
      781 accaaaatct tttaagtgct gagtttgtac ctgatgatcc ccctaaacct ggtgatacgt
      841 cagaacataa tcctaaaact cccgagttgg atggtagtcc tattcccgaa gacccaaaac
      901 atccagatga taatttagaa cctacattgc cgccagtgat gctagatggt gaagaagttc
      961 cagaagttcc aagcgagagc ttagaacctg cgcttccccc attgatgcca gagctagatg
     1021 gtgaagaagt cccagaagtt ccaagcgaga gcttagaacc tgcgcttccc ccattgatgc
     1081 cagagttaga tggtcaagaa gtccctgaaa aacctagtgt tgacttacct attgaagttc
     1141 ctcgttatga gtttaacaat aaagaccagt cacctctagc gggtgagtct ggtgagacgg
     1201 agtatattac cgaagtctat ggaaatcaac agaaccctgt tgatattgat aaaaaacttc
     1261 cgaatgaaac aggtttttca ggaaatatgg ttgagacaga agatacgaaa gagccagaag
     1321 tgttgatggg aggtcaaagt gagtctgttg aatttactaa agacactcaa acaggcatga
     1381 gtggtcaaac aactcctcag gttgagacag aagacacgaa agagccagga gtattgatgg
     1441 gaggtcaaag tgagtctgtt gaatttacta aagacactca aacaggcatg agcggtttca
     1501 gtgaaacagt gaccattgtt gaagatacgc gtccgaagtt agtgttccat tttgacaata
     1561 atgagcccaa agtggaagag aatcgggaaa agcctacaaa aaatataaca cctatccttc
     1621 ctgcaacagg agatattgga aatgttttgg cctttcttgg aatccttatt ttgtcagtac
     1681 tttctatttt tagcctttta aaaaacaaac aaaacaataa agtctgacgt aaaagtgttc
     1741 cataagaaat aatgcgcaaa tatgctgaat agtggataac tgctacagtc aagacaagtg
     1801 ttaattcaaa aggtactact tatacatctg ataataataa ggtgacagat aattcagagc
     1861 aagtaggatg gctaaaaaat gatgtattct atgcataata gacttacaag aaatcaagtt
     1921 attgttaaac gtcgtaaagc ttaacgcttt caaaagtcga aatcaatcga gactgtcttt
     1981 aggcagtctc gatttttatt gataaggaac tgcaatgaca gaaagactaa aaaatctagg
     2041 gatactctta ttatttttat tgggaacagc catttttctt taccctacgc taagtagtca
     2101 gtggaatgcc taccgtgatc gtcaattgtt atcaacttat cacaaacaag tgactcaaaa
     2161 gaagccctca gaaatggagg aggtgtggca aaaggctaag gcgtataacg ctaggcttgg
     2221 gattcagccc gttccagatg ctttttcatt tagggatggc attcatgata aaaactacga
     2281 aagcctactt caaattgaaa acaatgatat tatgggatat gttgaagtgc cctctattaa
     2341 agtgacgtta cccatatacc actatacgac agacgaggtg ctaactaagg gagcaggtca
     2401 cttagttgga agtgccttac cagttggtgg cgacgggact cacacggtta tttctgctca
     2461 tagaggcctt ccatcggcag aaatgtttac taatttgaat ttagtgaaaa ggggagatac
     2521 tttttacttt cgtgtgttaa ataaagtatt ggcttataaa gttgatcaga tactaactgt
     2581 tgaaccagat caagtcacat ctctttctgg ggtaatggga aaagattatg ctactctggt
     2641 tacctgcaca ccatatggtg ttaataccaa gcgtctattg gtcagaggtc atagaattgc
     2701 atatcattac aaaaagtatc aacaggctaa aaaagcaatg aaactcgtgg ataaatcaag
     2761 aatgtggaca gaagtagtat gtgctgcttt cggggtggtt atagctatta ttttagtatt
     2821 tatgtattca aagatgactg ataaaaaagt gattaaaaac taacttgccc tgaaccttct
     2881 ttatcgtatt gcaactgtca taaaagtaaa ataatctggt agttactatc ccctttgatg
     2941 aagtttaatt aaatctcatc aagagaaaaa tattaggcga ttacaaatga ttttcccaaa
     3001 aattattttt tggaacgcat aatatggaaa aaaagatgat aagaacaact gttttaaaca
     3061 tcaaataaat gatatagtag ctatgaaata gcattgtgac tgtccggtaa agggatggga
     3121 ctgaagattt tattcagaag gagagggaat gaataacaaa aaattgcaaa agaagcaaga
     3181 tgctcctcgg gtatcaaaca gaaagccaaa acaattaact gtcactttag tgggagtatt
     3241 tttaatgctc ttagtattga taggatttga aggaaaagtt cgagcagctc acgaattggt
     3301 tgaggtacca gtacctattt ttcacaatcc agatccacag tcagactatc agtggtatgg
     3361 ctatgaagcc tatacagggg ggtatccgaa gtatgattta ttcaagacat actatcatga
     3421 tctgagagtg aatttgcatg ggagtaaaag ttatcaagta tattgcttta acgttcacaa
     3481 acactatccc cgttcctccc agagttttga tcggaagtgg tataaaaaat tagatggaac
     3541 tgctgagaat tttgattctc ttgctatgga accaagagtt cgtaaagagg agttaaccaa
     3601 aaaactccta gctgttatgt ataatgccta tcctaatgat gctaatggca ttatgaaaga
     3661 tttagagcct ttaaatgcta ttaaagtcac tcaagaggct gtatggtact attctgattc
     3721 agctcaaatt aatccggatg aaagttttaa aacagaagct caaagtaatg gtattaatga
     3781 ccagcagtta ggcttaatgc gaaaagcttt aaaagaacta attgatccaa acttagggtc
     3841 aaaatattcg aataaaactc catcaggtta tcggttaaat gtatttgaat ctcatgataa
     3901 gactttccaa aatcttttga gtgctgagta tgttccggat actcccccaa aaccaggaga
     3961 agagcctccg gctaaaactg aaaaaacatc agtcattatc agaaaatatg cggaaggtga
     4021 ctactctaaa cttctagagg gagcaacttt gcgtttaaca ggggaagata tcccagattt
     4081 tcaagaaaaa gtcttccaaa gtaatggaac aggagaaaag attgaattat caaatgggac
     4141 ttatacctta acagaaacat catctccaga tggatataaa attgcggagc cgattaagtt
     4201 tagagtagtg aataaaaaag tatttatcgt ccaaaaagat ggttctcaag tggaaaatcc
     4261 aaacaaagaa gtaggttctc catatactat agaggcatac aatgattttg atgaatttgg
     4321 tttactgtca acacaaaatt atgcgaaatt ttattatgga aaaaactatg atggcagttc
     4381 acaaattgtt tattgcttca atgccaactt gaaatcccca cctgactcgg aagatcatgg
     4441 tgctacaata aatcctgact ttacgactgg tgatattagg tatagtcata ttgctggttc
     4501 agatttgata aaatacgcta atacagctag ggatgaagat cctcaattat ttttaaaaca
     4561 cgtaaaaaaa gtaattgaaa atgggtatca taaaaaaggt caagctattc catataacgg
     4621 tctgactgag gcacagtttc gcgcggctac tcaactggca atttattatt ttacagatag
     4681 tgttgactta actaaggata gattgaaaga cttccatgga tttggagata tgaatgatca
     4741 aactttgggt gtagctaaaa aaattgtaga atacgctttg agtgatgaag attcaaaact
     4801 aacaaatctt gatttcttcg tacctaataa tagcaaatac caatctctta ttgggacaga
     4861 ataccatcca gatgatttgg ttgacgtgat tcgtatggaa gataaaaagc aagaagttat
     4921 tccagtaatt catagtttga cggtgaaaaa aacagtagtc ggtgagttgg gagataagac
     4981 taaaggcttc caatttgaac ttgagttgaa agataaaact ggacagccta ttgtcgacgc
     5041 tctaaaaact aataatcaag atttagtagc taaagatggg aaatattcat ttaatctaaa
     5101 gcatggtgac accataagaa tagaaggatt accgacggga tattcttata ctctgaaaga
     5161 gactgaagct aaggattata tagtaaccgt tgataacaaa gttagtcaag aagctcaatc
     5221 agcaagtgag aatgtcacag cagacaaaga agtcactttt gaaaaccgta aagatcttgt
     5281 cccaccaact ggttttacta ctgatggtgg aacctatctg tggttattat tgcttgtccc
     5341 atttggtttg ttagtgtggt tctttggtcg taaaggacta aaaaatgact aattacctaa
     5401 atcgcttaaa tgagaatcca ctatttaaag ctttcatacg gttagtactt aagatttcta
     5461 ttattggatt tctaggttac attctatttc agtatgtttt tggcgtcatg attgttaaca
     5521 caaatcagat gagtcctgct gtaagtgctg gtgatggagt cttatattat cgtttgactg
     5581 atcgctatca tattaatgat gtggtggtct atgaggttga taacactttg aaagttggtc
     5641 gaattgccgc tcaagctggc gatgaggtta attttacgca agaaggagga ctgttgatta
     5701 atgggcatcc accagaaaaa gaggtccctt acctgacgta tcctcactca agtggcccaa
     5761 attttcccta taaagttcct acgggtacgt atttcatatt gaatgattat cgtgaagaac
     5821 gtttggacag tcgttattat ggggcgttac ccatcaatca aatcaaaggg aaaatctcaa
     5881 ctctattaag agtgagagga atttaaaaaa atttggagag agagaaaatg aaaaaaaata
     5941 aattattact tgctactgca atcttagcaa ctgctttagg aacagcttct ttaaatcaaa
     6001 acgtaaaatc tgagacggca ggagtgtccg aaaatgcaaa attaatagta aaaaagacat
     6061 ttgactctta tacagacaat gaagttttaa tgccaaaagc tgattatact tttaaagtag
     6121 aggcagatag ttctgcaact gataaaacga aagatggttt agagattaag ccaggagtaa
     6181 ctgaaggttt aactaccgag cagacaattg cttatgataa ctcagttaaa ccatcggata
     6241 aatctaagac tgcaactttt gatttttcaa ccgtaaaatt tccagaagtt ggtgtttatc
     6301 gttatacggt ttcagaaata gatagcaaag ttagtgggat taaatacgat accaaaacat
     6361 ggatagtgga tgtttatgtt gttaatgatg gtaatggagg atttaaggca cggtatattg
     6421 tatctaaaga gaagggacaa aatgataaaa agcctgttgt ttttgaaaac tcctttaaga
     6481 caacttcttt aaaggtagaa aaacaggtga ctggtaatac aggagaacta aagaaagact
     6541 tcaatttcac tttgacaatt aatcctaatg ataatttcgt agctggacaa gttattaaat
     6601 tagagaaagg tggaattaaa gctgatgtta agattggtga gccgtataaa tttgctctaa
     6661 agaatggtga gaaagtaact ttatcaaaat taccagtagg tgttacttat agcatcattg
     6721 aagatgaggc agataaagac ggatacacaa ctaatgccaa aattacagat ggtacggcag
     6781 cgcctgtgga atataagtta ggaaatcaac aattggctga cgaatctgct gacgaaatcg
     6841 ttgtcacaaa taaccgtgac actcaagttc caactggtgt tgtaggcacc cttgctccat
     6901 ttgcagttct tagcattgtg gctattggtg gagttatcta tattacaaaa cgtaaaaaag
     6961 cttaagtgat tagtcaaaga atgatgatga caattgtaca ggttatcaat aaagccattg
     7021 atactctcat tcttatcttt tgtttagtcg tactattttt agctggtttt ggtttgtggg
     7081 attcttatca tctctatcaa caagcagacg cttctaattt caaaaaattt aaaacagctc
     7141 aacaacagcc taaatttgaa gacttgttag ctttgaatga ggatgtcatt ggttggttaa
     7201 atatcccagg gactcatatt gattatcctc tagttcaggg aaaaacgaat ttagagtata
     7261 ttaataaagc agttgatggc agtgttgcca tgtctggtag tttattttta gatacacgga
     7321 atcataataa ttttacggac gattactctc tgatttatgg ccatcatatg gcaggtaatg
     7381 ccatgtttgg cgaaattcca aaatttttaa aaaaggattt tttcaacaaa cataataaag
     7441 ctatcattga aacaaaagag agaaaaaaac taaccgtcac tatttttgct tgtctcaaga
     7501 cagatgcctt tgaccagtta gtttttaatc ctaatgctat taccaatcaa gaccaacaaa
     7561 ggcagcttgt tgattatatc agtaaaagat caaaacaatt taaacctgtt aaattgaagc
     7621 atcatacaaa gttcgttgct ttttcaacgt gtgaaaattt ttctactgac aatcgtgtta
     7681 tcgttgtcgg tactattcaa gaataacgaa aggaggagac ttttgagaaa atattggaaa
     7741 atgttatttt ctgtcgtaat gatattaacc atgctggcct ttaatcagac tgttttagca
     7801 aaagacagca ctgttcaaac tagcattagt gtcgaaaatg tcttagagag agcaggcgat
     7861 agtaccccat tttcgattgc attagaatca attgatgcga tgaaaacaat agaagaaata
     7921 acaattgctg gttctggaaa agcaagcttt tcccctctga ccttcacaac agttgggcaa
     7981 tatacttatc gtgtttatca gaagccttca caaaataaag attatcaagc agatactact
     8041 gtatttgacg ttcttgtcta tgtgacctat gatgaagatg agactctagc cgcaaaagtt
     8101 atttctcgaa gggctggaga cgaagaaaaa tcagcgatta cttttaagcc caaacggtta
     8161 gtaaaaccaa taccgcctag acaacctgac atccctaaaa ccccattacc attagctggt
     8221 gaagtaaaaa gtttattggg tatcttaagt atcgtattac tgggattact agttcttctt
     8281 tatgttaaaa aactgaagag taggctataa aacccatttt taagagtcac acatttttag
     8341 ttgctctatt tttataatga aacttattga catctccata gtcttgcttg actttggaga
     8401 tgttttctat gctgataggt ttttgtacca tataagataa tgattgatga aaagagtgtc
     8461 ttgaattctt aaatattatc tcggtattta gcaagatagt cttttgaaga aatacccgtg
     8521 tattttttaa agattttatg aaaatgggta gtgtcataaa aatataagct tttagccact
     8581 tctccaacag gaattcctcg ttttaagagt agttgagctt ctttgatttt tgtacttaga
     8641 atataatgtt gtaaggaaac atttgagtat tttttaaaga ctgaacgtaa gtgagattcg
     8701 gaaacatata ggcgcttagc gatatcagat acctttaatt tggaatacag gtgactatcg
     8761 acataatgaa gcacactatt gtacatttga cgtttatcag aaatactttt attggttaat
     8821 gattcggaaa aatggatgat agctgcacag cgaattctca aaactttgag caagtcactc
     8881 gcttcttcat ttaaggccat gtagtatttg acaaggctat aatgctttgc tacgtcagta
     8941 ttttctacaa aactgaattc cagtaaccta gttaaataga taacagtgag gttcttttcc
     9001 gcccttagag cagaaataga agatgaggtg atacttgata aggggatgcg attgatttct
     9061 tgcttgagca attgtggatt gcctagcttt accagatcca taatatgatt taggtgctct
     9121 aaaacaggcg gtaattggct agatgctttg ctaatatgct taaggcgatg aatgatatca
     9181 ggatcagcag tcatctgttt tgaatgctgc aacaattgat gaattgtttg ttggcaagtc
     9241 gtctcaaatt gtgtgtcaaa aaaagcgtca atagctatca aaaggttccg cacattatta
     9301 attggaaaat gtgggacaag tgccatatag gacaagagct cttctttgct acgatgagaa
     9361 gaatgtttta aaaaattatt agctaattgt tcctgatagt ctttattaag tgaataaggg
     9421 tagaaaggtc caatggcaat aatgtagtga caaagaggaa aaatcataaa ggactcttca
     9481 aataaaccct cataaaaaat aacatcttgt gcggcttgag gaatagctag atgctttaaa
     9541 aattgatagt aacataataa atagtcgtca ttaccatata cttgaataag tgccttatct
     9601 tgtgacatca ctgaaatagg taattgagac aagctgtgta atgtttgcac atattttaaa
     9661 tcgaatataa ccatttgata gattgccccc catccttagt tgtatcattt tccttagact
     9721 tgtaaaagct ttagtaaatg ttaatgatga aaattcctat ttggtaggca cactaaaagg
     9781 ttttcctaat agtaaactct ctctccatca tctcctacct taattatact ataaatagct
     9841 aagcagataa agataaagga tttgtacgtt aagcgcttga aaaagaaaga gttacagata
     9901 atgacataaa aaacgctaaa aaaccatcaa aataaatact ctgaccataa gatgtagact
     9961 tgacaactga aaatggtaaa ataactattt gacagttgtc ctgtagtctt tagttttgga
    10021 cataggctgt cgcttatgaa tgtggagaga gaaaataaat gacacaaaaa aatagctata
    10081 agttaagctt cctgttatcc ttaacaggat ttattttagg tttattattg gtttttatag
    10141 gattgtccgg agtatcagta ggacatgcgg aaacaagaaa tggagcaaac aaacaaggat
    10201 cttttgaaat caagaaagtc gaccaaaaca ataagccctt atcgggagca actttttcac
    10261 tgacaccaaa ggatgggaag ggaaaacctg ttcagacctt tacctcaagc gaagagggta
    10321 ttatagatgc tcaaaatctc caaccaggga cttatacctt aaaagaagat aaagcaccag
    10381 atggttatga taaaaccagt cggacttgga cagtgactgt ttatgagaac ggctatacca
    10441 agttggttga aaatccctat aatggggaaa tcatcagtaa agcagggtca aaagatgtta
    10501 gtagttcttt acagttggaa aaatcaacaa tgtctgtatt ctctaaatac ggagggacag
    10561 aagtaactag tggcgcagcg gatttctacc gcaatcatgc cgcctatttt aaaatgtctt
    10621 ttgagttgaa acaaaaggat aaatctgaaa caatcaaccc aggcgatacc tttgtgttac
    10681 agctggacaa acgtctcaat cctaaaggta tcagtcaaga tatccctaaa atcatttatg
    10741 acagtgaaaa tagtccgctt gcgattggaa aatacgatgc caagactcat cagctcacct
    10801 atacttttac aaattatatc gctggtttag ataaagtcca gttgtctgca gaattgagct
    10861 tattcctaga gaataaggtt gttttagaaa atcaaacgat atcagatttt aagagtacca
    10921 taggtgatca ggaaatcaaa tatggtggga cagttaatgt cctttatgga aatgcatctg
    10981 ggcaagacaa caattatgtt actaacggat tgagcaatgt gggtggaagt attgaaagct
    11041 acaatacaca aacaggcgac tttacttggt atgtttatgt caacccaaat cgtaccaata
    11101 ttccttatgc gaccatgaat ttatggggat ttggaaggtt ggttaaatct aataactcaa
    11161 caagtaagtc agaggattcc gctacaagta gtgcccaatt ggaaaaagta gaaatttatg
    11221 aagttaaaga ggactatacg ctacccacta gttatggggt tgatctaaca aaattgaatt
    11281 taagaaaaga ccttgaggca aagttaccac aagatagtac tcaaaattct aataagcgct
    11341 tgcgaattga ctttggagat aaacttcaaa ataaagcctt tgttgttaaa ataacaggga
    11401 aaacggatca atctggtaag ccactagtcg ttcaatccaa tttggccagt tttaataatg
    11461 aaactgctgt aacttatggt aatcctgtta ataacgtcta cttccaaaac gaaattgcct
    11521 tgtctccttc taagggtagt ggttctggga caagtgaatt tactaagccc tctattacag
    11581 tagcaaatct aaaacgagtg gctcagcttc gctttaagaa aatgtcaact gacaatgtgc
    11641 cattgccaga agcggccttt gagctgcgtt catcaaatgg taatagtcaa aaagtagaag
    11701 caaaatcaaa cacacaagga gaggttcatt ttaaggacct gacctcgggc acctacgact
    11761 tgtatgaaaa acaagcacct aaaggctatc agcaggtgac agagaaattg gcgaccgtta
    11821 ctgttgatac taccaaacct gctgaggaaa tggtcacttg gggaagccca cattcgtctg
    11881 taaaagtaga agatagcaaa gaagtcacga ttgtcaacca taaagaaacc cttacgtttt
    11941 cagggaagaa aatttgggag aatgacagac cagatcaacg tcctgcaaag attcaagtgc
    12001 aactgttgca aaatggtcaa aaaatgtccg ataaagttca agaagtaacg aaggataacg
    12061 attggtctta tcacttcaaa gacttgccta agtacgatga caggaatcag gagtataagt
    12121 actcagttga agaagtgaaa gttccagacg gctacaaggt gtcgtattta ggaaatgata
    12181 tatttaacac cagagaaaca gaatttgtgt ttgaacagaa taactttaac cttgaatttg
    12241 gaaatgctga aataaaaggt caatctgggt caaaaatcat tgatgaagac acgctaacgt
    12301 ctttcaaagg taagaaaatt tggaaaaatg atacggcaga aaatcgtccc caagccattc
    12361 aagtgcagct ttatgctgat ggagtggctg tggaaggtca aaccaaattt atttctggct
    12421 caggtaatga gtggtcattt gagtttaaaa acttgaagaa gtataatgga acaggtaatg
    12481 acatcattta ctctgttaga gaagtaactg ttccaacagg ttatgatgtg acttactcag
    12541 ctaatgatat tattaatacc aaacgtgagg ttattacaca acaaggaccg aaactagaga
    12601 ttgaagaaac gcttccgcta gaatcaggtg cttcaggcgg taccactact gtcgaagact
    12661 cacgcccagt tgataccttg tcaggtttat caagtgagca aggtcagtcc ggtgatatga
    12721 caattgaaga agatagtgct acccatatta aattctcaaa acgtgatatt gacggcaaag
    12781 agttagctgg tgcaactatg gagttgcgtg attcatctgg taaaactatt agtacatgga
    12841 tttcagatgg acaagtaaaa gatttctacc tgatgccagg aaaatataca tttgtcgaaa
    12901 ccgcagcacc agacggttat gagatagcaa ctgctattac ctttacagtt aatgagcaag
    12961 gtcaggttac tgtaaatggc aaagcaacta aaggtgacgc tcatattgtc atggttgatg
    13021 cttacaagcc aactaagggt tcaggtcagg ttattgatat tgaagaaaag cttccagacg
    13081 agcaaggcca ttctggctca actactgaaa tagaagacag taaatcttca gaccttatca
    13141 ttggcggtca aggtgaagtt gttgacacaa cagaagacac acaaagtggt atgacaggcc
    13201 attctggctc aactactgaa atagaagaca gcaagtcttc agacgttatc attggcggtc
    13261 aggggcaggt tgtcgagaca acagaggata cccaaactgg catgcacggg gattctggtt
    13321 gtaaaacgga agtcgaagat actaaactag tacaatcctt ccactttgat aacaaggaat
    13381 cagaaagtaa ctctgagatt cctaaaaaag ataagccaaa gagtaatact agtttaccag
    13441 caactggtga gaagcaacat aatatgttct tttggatggt tacttcttgc tcacttatta
    13501 gtagtgtttt tgtaatatca ctaaaaacca aaaaacgcct atcatcatgt taagataagc
    13561 tgttggtgac aatagcgaaa aagggtccac ttgttagtgg acctcttttt ctggaatcga
    13621 tcgtctcggt tcactagata agtcatttta agtagttcaa aaaggcagag ccttaaaaag
    13681 ttttctgcct ttttaatctt gtggggcact tacgaaagta tttcggccac ttcaagcata
    13741 ataaaaagag tctgagcaat catgttgtct cagactctga ctgtaattat gcaaaagatg
    13801 atggactggc agcttcattt actcaccgaa ctccccttta taacttggga atgatgctgc
    13861 taatgggttg ttttgtttaa tacctgctat aaacggtaat ttatcccatt tatctttgta
    13921 attatcttca agctcagttt taaacttcca aaccatttta tgagaaaaat aagtgtgcga
    13981 ttgacggccg taggtgtcta ctaaaacgtg agaaaatttt ccgtcgtttt ttagtttgta
    14041 aaatttatct agagaaggac tccagccagt ataaccaggg aatttatcaa attcttgatt
    14101 aaaatttgtt tgttggcttc cccaatcata atgccattgt gtattattgt gttttttaga
    14161 atcaactgta ccgttcccat aatgatgctc ataagttatc tccgtaggag cttttacacc
    14221 cttaggaaga aacactgaga aatcagggta aacccattgt tctttagctg aattaaaggt
    14281 tacagtccat tcgatactgt tattgttatc gaccaatgtt ttagtatagt cgacatagtt
    14341 atcaacctag taatttccct gccagtaaag gtgcacttta cctttttcat caatgttatc
    14401 atgggcatgt actgatttat acgaactaaa cagcatcgaa gctgctagta gtgaagtgaa
    14461 gagatattta ttacatcgtt tcatatcatg aaaaaccttt cttttaatac taatatatta
    14521 tatcaaaaaa actaaaaagt aaattatttt tta
//
LOCUS       DATWVB010000040        13321 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.040, whole genome shotgun sequence.
ACCESSION   DATWVB010000040 DATWVB010000000
VERSION     DATWVB010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13321
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.040"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..669)
                     /locus_tag="VCX65_001424"
     CDS             complement(<1..669)
                     /locus_tag="VCX65_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053880.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNIN
                     TSADS"
     gene            complement(679..1377)
                     /locus_tag="VCX65_001425"
     CDS             complement(679..1377)
                     /locus_tag="VCX65_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053881.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(1377..1748)
                     /locus_tag="VCX65_001426"
     CDS             complement(1377..1748)
                     /locus_tag="VCX65_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP5053882.1"
                     /translation="MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            1933..5043
                     /locus_tag="VCX65_001427"
     CDS             1933..5043
                     /locus_tag="VCX65_001427"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEP5053883.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTTFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLRELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQIYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSNYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIVEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKIMDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEI
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            5123..6136
                     /gene="pfkA"
                     /locus_tag="VCX65_001428"
     CDS             5123..6136
                     /gene="pfkA"
                     /locus_tag="VCX65_001428"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEP5053884.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            6199..7701
                     /gene="pyk"
                     /locus_tag="VCX65_001429"
     CDS             6199..7701
                     /gene="pyk"
                     /locus_tag="VCX65_001429"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEP5053885.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICCETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            7919..8476
                     /gene="lepB"
                     /locus_tag="VCX65_001430"
     CDS             7919..8476
                     /gene="lepB"
                     /locus_tag="VCX65_001430"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEP5053886.1"
                     /translation="MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKS
                     GDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            8652..10466
                     /gene="glmS"
                     /locus_tag="VCX65_001431"
     CDS             8652..10466
                     /gene="glmS"
                     /locus_tag="VCX65_001431"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEP5053887.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAG
                     PEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
                     LVAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            10662..10997
                     /locus_tag="VCX65_001432"
     CDS             10662..10997
                     /locus_tag="VCX65_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEP5053888.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            11104..11745
                     /locus_tag="VCX65_001433"
     CDS             11104..11745
                     /locus_tag="VCX65_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP5053889.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            11755..12384
                     /locus_tag="VCX65_001434"
     CDS             11755..12384
                     /locus_tag="VCX65_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP5053890.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQKSDAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            12400..13236
                     /locus_tag="VCX65_001435"
     CDS             12400..13236
                     /locus_tag="VCX65_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP5053891.1"
                     /translation="MIIKKRTVAILAIASSFFLVACQATKGLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQEKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     SLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANI
                     KS"
BASE COUNT         4194 a         2205 c         2775 g         4147 t
ORIGIN      
        1 actatcggca cttgtattaa tattaaagat gtgactgtga acatatgttg cagcaacgct
       61 aatcagaata actaatataa aatatgcaat aaaggccatc aagcctcgcc gattagaaaa
      121 aagttgacct atagaaatgg aaagataaat taataagata ctcgtaaatg ttgataatag
      181 gacataggct agtacagtta gcatattgat gaaataatcc atcttaaaac tattaaagaa
      241 tccttctaat agttcgttga tgttaaacat tggtacaatt acaatagcga tagcaaatgc
      301 aaggatgata gtattgaaaa cactgcaaat aaaagaagct agtagttttg ataaaataat
      361 ttgatgcgaa ttaacgggta aagtcaacgt taagtatcct tcccgtccaa aaacactttt
      421 gctaaaacgt ttgataatga taagtaatgt tgataagagg gaaccagcga tcagggagcc
      481 aaaagttaaa cctaatgtca gaggtaacat cttattggtt agtactccaa atagtccatc
      541 actattactt tgagcaaaca gttttatcgt aaatgacaaa atggcagcga tggcaataac
      601 gaaagcatta agcgcaaagt accattttcc aatagatcta aattcgtatt ttaataattt
      661 tccaaacatg atatcctcct aaaccttata agtttcccta aagagggaat caatggattg
      721 ctggtattct tgtcttagat catcagcatt gccagataag aaaagtcttc cttgtttcaa
      781 gaaaatgact tcgtcaagga taggttcaat gtccgaaatc aagtgggttg agataataac
      841 agaagcattt tcacaataac tattaatgat ggtttttagg atgtagtctc ttgcggcagg
      901 gtcaactcca ccaataggtt catcaagtac atagagtctg gctttacgac tcatcacaag
      961 aattaattgt actttttctt tgtttccttt ggatagagtt ttgaagcggt cttcagggtc
     1021 tagttctaaa tctcttagaa ggcttgttgc tttggatttg tcaaagtcgc tgtaaaaatc
     1081 actaaagaac tccaacatgt ccttaattct catattttca ttgagataag tagtatctgg
     1141 taaataagaa ataatttttt ttgtctcaac acagggacgg tagccatcaa tgacaatttc
     1201 tcctttattt ggttgtaaaa ggccattaat gagtttaatt aaagttgttt taccacttcc
     1261 atttggacct aataatccga taattttacc gttcgggata gtaatggtta agtcatcaat
     1321 agcttttttt tcacggtaag attttgaaac atgatgtagt tgcaataggt gtgccattat
     1381 tgtgaatcct cctttaaaaa gctcgtcaaa acagggataa tctcagtgtg actaaatccc
     1441 atttttgtca tattggtgat aaatgattct aattcactaa ttgctaactc tcgtctttta
     1501 cgagcaatta atttttgatc gtcagttaca aaacggccag cagtacgttg cgaataaacc
     1561 attccttccc gttcaagttc tgtaaacgct cgttgcatgg tgttaggatt aacacctgcg
     1621 atttctgcat attcacgaac agttggaagt tgatcaccac tcttgatttc ttggctaata
     1681 atttgcatca tgacatgttg tgctatctgc gcataaatag gagatttttc atcaaatttc
     1741 caagacatgt ggtctccttt ctgagtaata tagatatttg tactaattaa atggtacaga
     1801 aaaaaaaagg gaatgtcaag ttttatgcca tttttcactc tttgagaagt agacgtagat
     1861 tagagagaaa attgaagcaa gaaaaccttt ttcatagtat aatagggaac aagataacca
     1921 aaggaggaac ttatgtttgc tcaacttgat actaaaactg tatactcatt tatggatagt
     1981 ttaattgact taaatcatta ttttgaacga gcaaagcaat ttggttacca caccatagga
     2041 atcatggata aggataatct ttatggtgct taccatttta ttaaaggttg tcaaaaaaat
     2101 ggactgcagc cagttttagg tttggaagta gagattctct atcaagagcg gcaggtgctc
     2161 cttaacttaa tcgcccagaa tacacaaggc tatcatcagc ttttaaaaat ttccacggca
     2221 aaaatgtctg gcaagcttca tatggattac ctctgccaac atttggaagg gatagcggtt
     2281 attattccta gtaagggttg gagcgataca ttagtggtcc cttttgacta ctatatcggt
     2341 gttgatcagt atactgattt atctcatatg gattctaaga ggcagcttat acccctaagg
     2401 acagttcgtt attttgcgca agatgatatg gaaaccttgc acatgttgca tgccattcga
     2461 gataacctca gtctggcaga gacccctgtg gtagaaagtg atcaagagtt agcagattgt
     2521 caacaactaa ccaccttcta tcaaacacac tgccctcaag ctctacagaa tttagaagac
     2581 ttagtgtcag gaatctatta tgatttcgat acaaatttaa aattgccaca ttttaataga
     2641 gataagtctg ccaagcaaga attgcaagac ttgactgagg ctggtttgaa ggaaaaagga
     2701 ttgtggaaag agccttatca atcgcgctta ctgcgtgaat tggtcattat ttctgacatg
     2761 ggctttgatg attatttttt gattgtgtgg gatttacttc gctttggacg cagtaaaggc
     2821 tattatatgg gtatgggacg tggctcggcg gcaggtagtc tagtggctta tgctctgaac
     2881 attacaggga ttgatccagt tcaacatgat ttgctatttg agcgcttttt aaacaaagaa
     2941 cgttatagca tgcctgatat tgatatcgat cttccagata tttaccgttc agaatttcta
     3001 cggtatgtcc gaaatcgtta tggtagcgac cattcggcgc aaattgtgac cttttcaacc
     3061 tttggcccta aacaggctat tcgtgatgtt ttcaaacggt tcggggttcc agaatacgaa
     3121 ctgactaatc tcactaaaaa aattggtttt aaagatagct tggctactgt ctatgaaaag
     3181 tcaatctctt ttaggcaggt tattaatagt agaactgaat ttcaaaaggc ctttgctatt
     3241 gccaagcgta tcgaaggaaa tccaagacaa acgtccattc acgcagctgg tattgtgatg
     3301 agtgatgata ccttgaccaa tcatattcct ctaaaatcgg gcgatgacat gatgatcacc
     3361 cagtatgatg ctcatgcggt cgaagctaat ggcctgttaa aaatggattt tttggggtta
     3421 agaaatttga cctttgttca aaaaatgcaa gagaaggttg ctaaagacta cgggtgtcag
     3481 atcgatattg cagccattga tttagaagac ccgcaaacgt tggcactttt tgctaaaggg
     3541 gataccaagg gaattttcca atttgaacaa aatggtgcta ttaatctttt aaaacggatt
     3601 aagccacaac gttttgaaga aattgttgcc actaccagtc taaatagacc aggggcaagt
     3661 gactatacca ctaatttcat taaacgaaga gaaggacaag aaaaaattga tttgattgat
     3721 cctgtgattg ctcccatttt agagccaact tacggtatta tgctttatca agaacaagtt
     3781 atgcagattg cacagattta tgctggtttt acgttaggca aggccgactt gttaaggcgt
     3841 gccatgtcta aaaaaaatct acaagaaatg caaaaaatgg aagaagactt tattgcttct
     3901 gctaagcacc tagggagagc tgaagaaaca gctagaggac tttttaaacg gatggaaaaa
     3961 tttgcaggtt atggttttaa ccgcagccat gcctttgcct attcagcttt agcttttcaa
     4021 ttggcttatt tcaaagccca ttacccggct gttttttacg atatcatgat gaattattct
     4081 agcagtaact atatcacaga tgctctagaa tcagattttc aagtagcgca agttaccatt
     4141 aatagtattc cttacactga taaaattgaa gctagcaaga tttacatggg gctgaaaaat
     4201 attaaggggt tgccaaggga ttttgcttat tggattgttg agcaaagacc atttaatagc
     4261 gtagaggatt ttctcactag aactccagaa aaatatcaaa aaaaggtttt ccttgagcct
     4321 ctgataaaaa taggtctgtt tgattgcttt gagcctaacc gtaaaaaaat tatggacaat
     4381 ttggatggtt tactggtatt tgttaatgag cttggttctc ttttttcaga ttcgtccttt
     4441 agttgggtag atacgaaaga ttactcagca actgaaaaat attctttgga acaggagatc
     4501 gttggggttg gcatgagcaa gcatccttta attgatattg ctgagaaaag tacccaaact
     4561 tttactccca tttcacagtt agtcaaagaa agcgaagcag tcgtactgat tcaaatagat
     4621 agcattagga tcattagaac caaaacaagt gggcagcaaa tggctttttt aagtgtgaat
     4681 gacactaaga aaaagctcga tgtcacactt tttccacaag agtatgctat ttataaagac
     4741 caattaaaag aaggagaatt ctattactta aaaggtagaa taaaagaaag agaccatcga
     4801 ctgcagatgg tgtgtcagca agtgcaaatg gctattagtc aaaaatattg gttattagtt
     4861 gaaaaccatc agtttgattc ccaaatttct gagattttag gtgcctttcc aggaacgact
     4921 ccagttgtta ttcactatca aaaaaataag gaaacaattg cattaactaa gattcaggtt
     4981 catgtaacag agaatttaaa ggaaaaactt cgtccttttg ttctgaaaac ggtttttcga
     5041 taaaaatgga caattagtga agtattttgc aaatgaatgt gctataataa gaccgttaaa
     5101 ttaattaaag gagtaccaga aaatgaaacg tattgctgtt ttaaccagtg gcggcgacgc
     5161 tcctggtatg aacgctgcta ttcgtgcagt cgttcgtaaa gcaatttcag aaggaatgga
     5221 agtttatggt atcaaccgtg gctatgcagg tatggttgat ggcgacattt tcccactggg
     5281 ttcaaaagaa gttggtgata aaatctcacg tggtggaact ttcttatact cagctcgtta
     5341 tccagagttt gctcaacttg aaggtcaatt ggctggtatt gagcaactta aaaaacatgg
     5401 tattgaaggt gttgttgtta ttggtgggga tggttcttat catggcgcta tgcgcttgac
     5461 agagcacggc ttcccagcgg taggtatccc aggaacaatc gataacgata ttgcgggaac
     5521 tgactacact atcggatttg atacagcagt taacacagct gttgaagcta ttgataaact
     5581 tcgtgacacc tcatcaagtc acggacgtac ttttgtggtt gaagtgatgg gtcgcaatgc
     5641 gggtgatatt gctctttggg caggtattgc tagtggtgct gatcaaatca ttgttccaga
     5701 agaagagttt gatattgaaa aagtggcatc aacaatccaa tatgattttg aacacaaagg
     5761 taaaaatcac cacattatcg tcttagctga aggtgttatg agcggtgaag cttttgctca
     5821 aaaactgaaa gaagctggcg ataagagtga ccttcgtgtg acaaatcttg gccacattct
     5881 tcgtgggggt tcaccaactg ctcgtgaccg tgtcattgct tcttggatgg gttcacatgc
     5941 tgttgagcta cttaaagaag gcaaaggtgg tttggctgtt ggtattcaca atgaagaact
     6001 tgttgaaagc ccaatccttg gtactgcaga agaaggtgct ttgttcagct tgactgaaga
     6061 aggcaagatt attgttaata atccacacaa agctcgttta gactttgcag ctttgaaccg
     6121 ttcattgtca caataagttt agttaaaatt gttaaatcgt caattattga caaaaaaata
     6181 agggagtttc agagtaaaat gaataaacgc gtaaaaatcg ttgcaacact tggtcctgcg
     6241 gttgaaatcc gtggtggtaa aaaatacgga gaagatggct actgggctgg tcaacttgat
     6301 gttgaagaat ctgcaaaaaa aatcgctgaa ttaattgaag ctggtgcgaa tgttttccgt
     6361 ttcaatttct cacatggtga ccacaaagaa caaggtgacc gtatggcaac tgtccgcctt
     6421 gcagaagaaa ttgctcgtca aaaagttggt ttccttttgg atactaaagg tcctgaaatg
     6481 cgtacggaat tgtttgcaga tgatgctaaa gagttcagct atgttactgg agaaaaaatc
     6541 cgtgtagcga ctacacaagg tattcaatca actcgtgatg ttattgcttt gaacgttgct
     6601 ggtagccttg acatctacga tgaagtagaa gtaggtcata ctattcttat cgatgatggt
     6661 aaacttggtt tgaaagtgat cgacaaagat atcgcaacac gtcaatttat cgttgaagta
     6721 gaaaacgacg gtattattgc taaacaaaaa ggtgttaata tccctaacac taaaattcct
     6781 ttcccagcac ttgcggaacg cgacaatgct gatatccgtt ttggtcttga acaaggactt
     6841 aactttattg caatctcatt tgttcgtaca gccaaagacg ttgaggaagt tcgtgaaatc
     6901 tgttgcgaaa ctggtaacga ccatgtgcaa ttatttgcta agattgaaaa ccaacaaggt
     6961 atcgataatc ttgatgaaat catcgaagct gctgatggta tcatgattgc acgtggcgac
     7021 atgggtatcg aagtaccatt tgaaatggtt ccagttttcc aaaaaatgat tatcactaaa
     7081 gtgaatgcag ctggtaaagc agttatcaca gcaacaaaca tgcttgaaac aatgactgaa
     7141 aaaccacgtg cgacacgttc tgaagtatct gacgtcttca atgctgttat cgatggtact
     7201 gatgcaacaa tgctttcagg agagtcagct aacggtaaat acccggttga atctgttcgt
     7261 acaatggcga ctattgatcg taatgcacaa actcttctta acgaatatgg tcgtttagat
     7321 tcatctgcct ttccacgtac caataaaaca gatgttattg cttcagctgt taaagatgcc
     7381 actcattcaa tggacatcaa acttgttgtg actattactg agacaggtaa tacagctcgt
     7441 gcgatttcta aattccgtcc agatgcggac atcttagctg taacatttga tgaaaaagta
     7501 caacgtgctt tgatgattaa ctggggtgtt attcctgttc ttgctgaaaa acctgcatct
     7561 actgatgaca tgtttgaagt agcagagcgt gttgctgtgg aggcaggctt agttcaatct
     7621 ggggataata ttgttattgt tgctggtgtt ccagttggta ctggtggaac gaatactatg
     7681 cgtgttcgta cagtaaaata aatgtgttat aactatttac ctaaaggtta gaaggcaagc
     7741 ttctaacctt ttttgatatc aaaaatatca tgttaattca ctagtgttaa tttactttaa
     7801 tgagtctaag tttgtatttt atacagaatg agaaacgttt attggtattg atcaaaaatt
     7861 gtttactttt tttctagctt agaacatggt ataataagac aatagactag gagttaatat
     7921 ggtaaagcga gattttataa gaaatatatt attgttatta attgtgatta ttggggctat
     7981 tttgttgaga atctttgttt tttcaacttt taaagtttct ccagaaacag ctaatactta
     8041 tttaaagagt ggtgatttag tcacaatcaa aaaaaatatt cagcccaaat ataaagattt
     8101 tgtggtttat agagttggaa aaaaagatta tgtcagtcga gtcattgctg ttgaaggcga
     8161 tagcgtgact tatatggacg atatttttta cctcaataat atggtagagt cacaggctta
     8221 ccttgaaaag atgaaagcac attacttgaa tcatgcaccg tttggcacat tgtatacaga
     8281 tgattttaca gttgctacca tcacagctga taagtatcaa aaagttccta aggggaagta
     8341 tcttcttttg aatgataacc ggaaaaatac gaatgacagt cgtcgatttg ggttaataaa
     8401 tgcctcgcag attaaaggtt tagtgacctt tagagttttg cctctcagcg attttggatt
     8461 tgtagaagta gagtagttgt caggctactc tacttttttt ataattagac tataccaatt
     8521 ttatgtttga caagacattg tggatattat atactgtaaa catactgttt ttatcggtat
     8581 aatatgacta taccaattat tgaaattatg agagaaagta gcaagttaac gaacttgtta
     8641 aggtaattaa gatgtgtgga attgttggag ttgttggaaa tcgcaatgca acggatattt
     8701 taatgcaagg ccttgaaaag cttgaatacc ggggttatga ttcagcagga atttttgtgg
     8761 ctaatgccaa tcaaacaaac ttgattaaat cagtggggcg gattgctgat ttgcgtgcca
     8821 agattggcat tgatgttgct ggttcaacag ggattggtca cacccgttgg gcaacgcatg
     8881 gccaatcaac agaggataat gcccatcctc acacgtcaca aactggacgt tttgtacttg
     8941 ttcataatgg tgtgattgaa aattaccttc acattaaaac agagttccta gctggacatg
     9001 attttaaggg gcagacagat actgagattg cagtacactt gattggaaaa tttgtggaag
     9061 aagacaagtt gtcagtactg gaagctttta aaaaagcttt aagcattatt gaaggttcct
     9121 acgcctttgc gttaatggat agccaagcaa ctgatactat ttatgtggct aaaaacaagt
     9181 ctccattgtt gattggactt ggtgaaggtt acaacatggt ttgttcagat gccatggcca
     9241 tgattcgtga aaccagtgaa tttatggaaa ttcatgataa ggagctagtt attttaacca
     9301 aagataaggt aactgttaca gactacgatg gtaaagagct gatacgagat tcctacactg
     9361 ctgaattaga cttatctgat attggcaaag ggacttatcc tttctatatg ctgaaagaaa
     9421 ttgatgagca accaaccgta atgcgtcaat taatttcaac ttatgcagat gaaactggta
     9481 acgtacaggt tgatccagct atcattacct ctatccaaga ggctgaccgt ctttatattt
     9541 tagcggcagg gacttcctac catgctggtt ttgcaacaaa aaatatgctt gagcaattga
     9601 cagatacacc agttgagttg ggagtggctt ctgagtgggg ttaccacatg cctctgctta
     9661 gcaagaaacc aatgtttatt ctactaagcc aatcaggaga aaccgcagat agtcgtcaag
     9721 ttttagtaaa ggcaaatgct atgggtattc cgagtttgac agtaactaac gttccaggat
     9781 caaccttatc acgtgaagca acatacacca tgttgattca tgctggacct gaaattgctg
     9841 ttgcgtctac aaaagcttac actgcacaaa ttgctgccct tgcctttttg gctaaggcag
     9901 ttggtgaggc aaatggtaag caagaagctc ttgactttaa cttggtacat gagttgtcat
     9961 tggttgccca atctattgag gcgactttgt ctgaaaaaga tctcgtggca gaaaaggttc
    10021 aagctttgct agctactact cgtaatgctt tttacattgg gcgtggcaat gattattacg
    10081 ttgcgatgga agctgctttg aaattaaaag agatttctta tattcaatgc gaaggctttg
    10141 cggctggtga attgaaacat ggaaccattt cattgattga ggaggacacg ccagtaatcg
    10201 ctttaatatc gtctagtcag ttggttgcct ctcatacgcg tggtaatatt caagaagttg
    10261 ctgcccgtgg ggctcatgtt ttaacagttg tggaagaagg gcttgaccgt gagggagatg
    10321 acattattgt caataaggtt catcctttcc tagccccgat tgctatggtc attccaactc
    10381 aactgattgc ttactacgct tcattacaac gtggacttga tgttgataag ccacgtaatt
    10441 tggctaaagc tgtaacagta gaataaatga ttataatgga taaggcaacc atctgttagg
    10501 tggttgcttt ttgtttttag gagaatagca gagcttagaa aatggccttg agaaaagcta
    10561 tacaagaaga atagtcatct tctgatgaga acgtattcat cttgtcaaat cattgattct
    10621 aaagtaaaat ggtaacatta agaaatgttt aggagtgtaa gatgtcatta ccaaattgtt
    10681 tgcaatgcca gtctgaatat gtttacgaag atggtctttt attaatctgt ccaatgtgtg
    10741 cttttgaatg gacaccaggc gaagaagcga ctgaagaaga aggacttgtt gttttagata
    10801 gcaatggtgt ccgactgtct gatggtgata ccattactgt ggttaaagat ttgaaagtaa
    10861 aaggcgctcc aaaagacctg aaacaaggga ctcgtgttaa aaatattcgc ctggtggaag
    10921 gtgatcataa cattgattgt aagattgatg ggtttggcgc gatgaaattg aaatcagaat
    10981 ttgtcaagaa aatctaataa taatacgcaa ccagctgatc tggttgtatt tttataaaaa
    11041 aacctctccc caaatacgtt caaatttggt ataatagtaa aatattcagt tttaggaggc
    11101 aacatgacct atattcagca agttttaccc agcttattag atggtgcctt ggtgacctta
    11161 caagtattct ttattgttat cattctttct atacccttag gggctatttt agctttcttg
    11221 atgaagattc cctttaaacc gctacagtgg tttttgaccc tatacgtgtg gatgatgcga
    11281 gggacaccat tactacttca attgattttt ttctattatg ttttgccaag tgtggggatt
    11341 agttttgatc gaatgccagc tgctattttg gcgtttactt tgaattatgc tgcctacttt
    11401 gctgaaattt ttagaggtgg gattgaggct attccaaaag gtcaatatga agcagctaaa
    11461 gtattaaagt taaaacctct tcaaaccatt cgttatatta ttttgcctca agtgtttaaa
    11521 attgtgttac caagtgtttt caatgaagtc attaatttgg tcaaagattc ttcccttgtc
    11581 tatgtactcg gtgtaggaga tcttttatta gcaagtaaga cggcagccaa tagggatgca
    11641 accttagccc ctatgtttat cgctggtctt atctatttgc ttttaattgg actggtcacg
    11701 attatttcaa aacaagttga aaaacggttt aattattatc agtaaggagg cttcatgtta
    11761 gaactcaaaa atatttccaa acagtttggt caaaaaacca tttttgatgg ctttaatcta
    11821 accgttcaag acggagaagt gctctctttg gtaggcccat caggtggcgg taagacaaca
    11881 ctcttacgga tgttggctgg tcttgaatct attgattcag gtcaagtctt ttacaatggc
    11941 gaagatgttg gtattgatca tttggaaaat cgtaacttgc ttggatttgt ttttcaagat
    12001 tttcaattgt ttcctcatct taccgtttta gacaacctaa cgctgtctcc aacaattaca
    12061 atgggcaagc aaaaatctga cgctaaagaa aaggctttgg atttactggc acgtttagga
    12121 ttaaaagaac atgcccaagt ttatccctat tcgttatctg gaggtcaaaa acaacgggtt
    12181 gctttggcaa gagccatgat gattgaccct caaattatcg gttacgatga accgaccagt
    12241 gctctagatc ctgaattacg tcagacggta gaagccttga ttgttcaaaa ccgtgaaatg
    12301 ggaataactc aaattgtagt cactcacgat cttgtttttg ccgaagccat ctcagatcgt
    12361 attattaggg ttaatcctaa atagaagagg acccaaaaga tgattataaa aaaaagaacc
    12421 gtagcaattt tagccatagc tagtagcttt ttcttggtag cttgtcaagc tactaaaggt
    12481 cttaaatcag gagatgcttg gggagtttac caaaagcaaa aaagtattac agttggtttt
    12541 gacaatacgt ttgttcctat gggctataag gatgaaagcg gcaaatgcaa aggttttgat
    12601 attgatttgg ctaaagaagt ttttcaccaa tatggactca aggttaactt tcaagctatt
    12661 aattgggaca tgaaagaagc agaactaaac aatggtaaaa ttgatgtaat ctggaatggt
    12721 tattcaataa ctaaggagcg tcaggaaaag gttgccttta ctgattctta catgagaaat
    12781 gaacaaatta ttgttgtcaa aaaaagatct gatattaaaa caatatcaga tatgaaacat
    12841 aaagtgttag gagcacaatc agcttcatca ggttatgact ccttgttaag aactcctaaa
    12901 ctgctgaaag attttattaa aaataaagac gctaatcaat atgaaacctt tacacaagct
    12961 tttattgatt taaaatcaga tcgtatcgat ggaatattga ttgacaaagt atatgccaat
    13021 tactatttag caaaagaagg gcaattggag aattatcgga tgatcccaac gacctttgaa
    13081 aatgaagcat tttcggttgg acttagaaaa gaagacaaaa cgttgcaagc aaaaattaat
    13141 cgtgctttca gggtgcttta tcaaaatggc aaatttcaag ctatttctga gaaatggttt
    13201 ggagatgatg ttgccactgc caatattaaa tcttaaaaag gacacttgtc ctttttttgt
    13261 ttaacaggtg agatctagca gacaaagtca gctagatgat ttaataaaaa tcttagttta
    13321 a
//
LOCUS       DATWVB010000041        13253 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.041, whole genome shotgun sequence.
ACCESSION   DATWVB010000041 DATWVB010000000
VERSION     DATWVB010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13253
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.041"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            52..1770
                     /locus_tag="VCX65_001436"
     CDS             52..1770
                     /locus_tag="VCX65_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053892.1"
                     /translation="MTVFLVIFLIYFNNFFVKKRSQELGVLAILGFSKKELTQLLTLE
                     NLVILVLSYLVSLLLGPTLYFLAVLVITHLLELTLEVQWFITANEIIESLGILVVVFL
                     INVITNGLIISKQSLIEFVNFSRKAEKKIKIRKVRAIIAITALLLSYILCLATVFSST
                     RNMLLSIGMVPVSLLIIVLVVLGTVFTIRYGLAFIVSLLKGNKKRLYRPLSNIIYPKF
                     NYRIATKNKLLTVLGGLLTVTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVKSENGQV
                     NVTTILENDQVSLVDVDLLRLNTNPEVTITESGQTIPYFDIINYSDYKELMKAQGRIN
                     SIEGSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTHNVFSFSTSVTTLVVSDK
                     LYAKLSSCFPEKEMTIRTFNGNSIRSSEAFYNQFSMVPDVISSYSKEYTVKTANIATY
                     IFITFLSILFIICTGSILYFTSLIEIMENKEEYGYLSKLGYSKKMIHRIPRYETGILF
                     LIPVFIGIVNGGMLLIYYKYLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVLTLRSV
                     TSIIKN"
     gene            1810..3372
                     /locus_tag="VCX65_001437"
     CDS             1810..3372
                     /locus_tag="VCX65_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEP5053893.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILVYNRENLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYTVEITNLILYGHKQFKDKLDKGLLIIIFVSITSLFVNSILFNFLFLMVFTI
                     LHLYPLLVIVLYYRSFRQQISVVRRSLILFSLLLLVILGSELYGEMLDVNQAFNNLGW
                     YLFPLIMSVIYYFKTIHDKLSFVTQRWLGDYKARIELLFLLLILCWIVLMKVLVKDFL
                     LFFIVVDASTLFCLVVISCIFYYLKDSKQNFDYENRRLNYFMKSEENMRVEFSNYLHD
                     DVLQNIIAIKNLLSLENSNITHGFIVNELNDLVSGIRDEMDTYYPIVPANQTMKENIQ
                     SLFDDIVKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIKYGDGKDIRLSL
                     TIQSDIIIIEESNQVVEKVHSISYGRGLKSFQETLAAFDGDLELQMDTKQFTIRILLP
                     IDWKLCYEDFIN"
     gene            3353..3958
                     /locus_tag="VCX65_001438"
     CDS             3353..3958
                     /locus_tag="VCX65_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5053894.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDITLLDINLTNISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(4510..6090)
                     /locus_tag="VCX65_001439"
     CDS             complement(4510..6090)
                     /locus_tag="VCX65_001439"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEP5053895.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLFAVCDNLEEHFNTFTDAQKIFENAYQDEGLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGWEDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDSHIKKILDAYKSRDNSDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(6103..7290)
                     /locus_tag="VCX65_001440"
     CDS             complement(6103..7290)
                     /locus_tag="VCX65_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEP5053896.1"
                     /translation="MTKSKRPQYRFDSFEGEWEEKKLGEISNIVRGASPRPIQDPKWF
                     DAKSDIGWLRISDVTEQEGRITYLQQRISELGQEKTRVLKDPHLLLSIAATVGKPVIN
                     YVKTGVHDGFLVFLDPKFNREFMFQWLDMFRPYWNKYGQPGSQVNLNSEIIRNQVINL
                     PSLPEQEAIGELFQTVDQLIQLQRQKLAILKEQKQTFLRKMFPAQGQKVPEIRLQGFD
                     GEWEEKELGDIVQITMGQSPSSQNYTTNPSDYILVQGNADIKNGYVFPRVWTTQITKQ
                     ADKGDIILSVRAPVGDVGKTNYHVIIGRGVAAIKGNEFIFQILKYLKEIGYWKRISTG
                     STFDSISSSDIKYAKIQIPSLSEQEAIGNFFQTLDQQIAQSEEKLTELKALKQTLLNR
                     LFV"
     gene            complement(7303..10281)
                     /locus_tag="VCX65_001441"
     CDS             complement(7303..10281)
                     /locus_tag="VCX65_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEP5053897.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     TIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPRAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTASAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVATTIQKLNAMISQMESYDTPKFKKLKERLAHLNVV
                     FVVDECHRAVTPERQRYLTNTFRNSRWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLDSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLMKKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDTALSLYSNGGQSEVLAPSWEEEKARFFEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAFQAFDKLYASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIAYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGISTLKESLDYQAYKEKQGDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            10562..11704
                     /locus_tag="VCX65_001442"
     CDS             10562..11704
                     /locus_tag="VCX65_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEP5053898.1"
                     /translation="MTINRVLKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNT
                     SVAQALLSVDKQLVIETRAIADGGEGSLAALSQTVAGRWHQVKTIDLLRRPIKVAYYR
                     HAKQAFIESASIIGIDKITPNSVTYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTS
                     DGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSL
                     SQIEETDQIASNFAKKVFYQKTIDLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAEL
                     LNLDNSLQSCDLVITGEGCLDTQSQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLA
                     AEDFLAVFSIQQQPISLEAAIDKTTTLSNIKILVANLMLLIAQFNK"
     gene            12092..>13253
                     /locus_tag="VCX65_001443"
     rRNA            12092..>13253
                     /locus_tag="VCX65_001443"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         4046 a         2223 c         2617 g         4367 t
ORIGIN      
        1 attggggata gtggtcaagc tctagttatt gctaacgggt cattagtttt tttgactgta
       61 tttttggtga tatttttaat ttatttcaat aatttctttg taaaaaaacg tagtcaagag
      121 cttggagtct tagcaatact agggttttca aaaaaagaat taacacaatt actgacttta
      181 gaaaatcttg ttattctagt tttaagttac ttggtaagtt tactattggg accgacctta
      241 tattttttag cggtactggt aattactcat ctattggaat taacattgga agttcagtgg
      301 tttattacag ctaatgagat tatagagtct ttaggaatat tagtcgtagt ttttctgatt
      361 aatgtcatca caaatggact tatcattagt aaacagtctt tgattgaatt tgttaatttc
      421 tcaagaaagg ctgagaaaaa aattaagata agaaaagtca gagctattat tgctatcact
      481 gcattgctat tgtcatatat tttatgtttg gcgacagtgt tttcatccac acgaaatatg
      541 ctattaagca tagggatggt accggtttct ctattgataa ttgtcttagt tgttttagga
      601 acagtgttca ccatcagata tggattggct tttatagttt cgttattaaa aggaaataaa
      661 aaaaggttat accgtcctct gtctaatatc atctatccca aatttaacta tcgtattgca
      721 acaaaaaata aattattaac agtcttggga ggtcttttaa cagtaaccgt ttcagttgct
      781 ggaatgatgg taatgctcta tgcttattct cttaatggga tagagaggtt gactccatct
      841 gccatagaat ataatgttaa atcagaaaac ggtcaagtca atgttacaac tattttagag
      901 aacgaccaag tgagcttggt tgatgttgac ctattgagat tgaacactaa cccagaagta
      961 actatcacag aatctgggca aacaattcct tattttgata taattaatta cagtgattat
     1021 aaagagttaa tgaaagctca agggagaata aattctattg aaggtagtaa gtcactccca
     1081 ttgttaataa attattatcc aacagaaatt agccttggaa aaacctttaa cttaggaaat
     1141 gcatatgatg ttactgtaaa acaagtatca acgcataatg tttttagttt ttctacaagt
     1201 gtcacgacct tggttgtttc tgataaatta tatgctaaac ttagttcttg ttttccagag
     1261 aaagaaatga caattaggac ttttaatgga aattcgatta ggtcaagtga agcattttac
     1321 aatcagttta gtatggttcc tgatgttatc agtagttata gtaaggaata cacagtaaag
     1381 actgctaata ttgcgactta tatctttata actttcctat ccatactctt tattatttgt
     1441 acaggtagta ttctgtactt tacaagcctc atcgaaatca tggaaaataa agaagaatat
     1501 ggctatctaa gtaagctagg ttatagtaaa aaaatgattc atcggattcc tcgatatgaa
     1561 acaggtatac ttttccttat tcctgtattc attgggattg taaatggtgg tatgttgctt
     1621 atttactata aatatttatt catggataca ttggtagcag gcaatatcat aatgttatct
     1681 ttattgcttt gtctgctttt cttcttgata atatatggca cattttatgt attgacattg
     1741 cggtcagtga catccataat caaaaattaa ttttaaaaat cttttaactt taacgattaa
     1801 gtaaataata tgataagaat aaaaaacata acaaagagta agttctttgg gactgcaata
     1861 atcttgttgc aacaattaat agccttgtta attttggtct ataatcgaga gaacctgtct
     1921 cttcttttct ctgaaaaagt agctcttgta atgaccctta ttgatacagc ttttatttgg
     1981 ctggcaacaa tattacgcca aaaacaaggt gatattttta aaaggattat ttctatcatc
     2041 tccttaacaa tttggcaata cttagtatct gtgctgacaa gaggaactcc tctcttttta
     2101 agcagtggac tacagattat attgctctat tgttataccg ttgagattac taatttaata
     2161 ttatatgggc acaaacaatt taaagataag ttagataagg gcttgttaat aattattttt
     2221 gtttctataa ctagcctttt tgttaatagc attttattta attttttatt cctgatggtt
     2281 tttactattt tacacctgta tccgttacta gttatagtgc tatattatag gtcctttagg
     2341 caacaaatat cagttgttag acgttcattg atactatttt ctttactttt gctggtaata
     2401 cttggtagtg aactttatgg agaaatgcta gatgttaatc aagcctttaa taatttggga
     2461 tggtatctgt ttccccttat aatgagtgta atatactatt ttaagaccat acatgataaa
     2521 ttgagttttg ttacccaaag atggttaggt gattacaaag ctcgtataga actattattt
     2581 ctacttctta tcctttgttg gattgtactc atgaaggtat tagttaaaga ttttttgcta
     2641 ttttttatag ttgttgacgc aagcacattg ttttgtctag tggtaatttc ttgcatcttt
     2701 tattatttaa aagactccaa acaaaatttt gactatgaaa atagaagact gaactatttt
     2761 atgaaatcag aggaaaacat gagagtggag ttctcaaatt atttgcatga tgatgtttta
     2821 caaaatatca tagcgataaa aaacttgctt tctctagaaa atagtaatat aacacatggt
     2881 tttattgtta atgagttgaa tgatttagtt tctggtatca gagatgaaat ggatacttac
     2941 tacccaatag ttcccgctaa tcaaacaatg aaagaaaaca tacagtctct ttttgatgat
     3001 attgttaaaa gtagaaaaag taatacccta ttgtatttta actgttcaga taatatggta
     3061 gtgccatccc catatggaga tattgtttat aggtttataa aagagctaat aaacaatgct
     3121 ataaaatatg gagatggaaa agacattcgt ttatctttaa cgattcaatc tgatattatt
     3181 atcattgagg agagcaatca agtagtggaa aaagtacact ctataagtta tggcagagga
     3241 ttgaaatcat ttcaagaaac actagcagct tttgatggag atctagaact acaaatggat
     3301 actaaacaat ttactatcag aatattactt cccatagatt ggaaattgtg ttatgaagat
     3361 tttattaatt gatgaccaca gactatttgc aaagagtatc caactgttat tccaacagta
     3421 tgatgaagta gatgtcatag atacgattac ttctcatttt aacgatgtga cgattgattt
     3481 gtctaagtac gatattacat tgcttgatat taatttaaca aatatttcta aagaaaatgg
     3541 attggagata gcaaaagaac tcatacagtc tactcctcat ttgaaagttg ttatgttgac
     3601 aggatatgtt aaatcaatct atagagagag ggcaaaaaaa gtaggagcat acggttttgt
     3661 agataaaaat atagacccta aacaactcat ttctatctta aaaaaagtgg attctggaaa
     3721 aaagtatttt gaacaaatcg aatctcagga ttatgttgaa tctttaactg accaggaaat
     3781 agctatctta aatttgagta agaaaggatt ctctataaaa gaaatagagg aaacgttaca
     3841 aattagtagg agaacagtat ttaatcattt gacccacatc tactcaaagc ttttggtaaa
     3901 taataagcaa gaggctatct acaaagccga acaattaggg tattttatgg atttctgagt
     3961 tgcagataat caaacgacat aagttttact tgtgtcgttg ctagggattt cctgttaaat
     4021 acccagattt aaactcattg tttttgagtt ctttttgatt gaaattgatt gagataacgc
     4081 ttttataaaa agtagggcaa tgcctgatat gaaaagcttt ttaaatttag tcaaacaaaa
     4141 gttgtttaaa ccaggtctaa aaaaactcgt aaagcttcac aactcccaga acgttaatat
     4201 atgcttatat atcaacgatt ggaactactt tatggttcgc accatggttt ttgtggaagg
     4261 atcaaaagtt gtcctgaaaa tttctcttaa ccgtgtttaa gctttctaaa cgtttgagaa
     4321 atcattgtaa cttcaaataa ctattttaaa taaaacaaag aaacggacaa agttagatga
     4381 gatgattcta ttttgattta taggtgaaga aggagaatct tgtttgataa gtactcaata
     4441 aaggttcact acccaatttt aaataaaacg ccacagtagt aatcatctac tgtggtgttt
     4501 tttggtcttt tagtttctaa aagtatccaa ttcgtcttgt gcttctttgg ttgttccgac
     4561 tagttgtttc atgagttgat ctagtttggc atttgttttg gcaatttctt gatcaatgtc
     4621 actgagctgt ttagctaatt ctggcagtgg tttgacgggg acttcctcaa aggtatcgac
     4681 atagcgtggg atatttaagt tatagtcatt ttcaatgatt tcatcaaatg aggctaaata
     4741 tgaaaactta tcagaattat cacgactctt ataagcatca aggatctttt tgatatggct
     4801 atctgtcatt gtgttttgat ttttgccttt atcaaactct tttgaagcat cgataaagaa
     4861 gacatctttg ttggttctgt tcttctttaa tatgataata gtcgtaggga tgcttgtatt
     4921 ataaaagata tttgatggga gtccgataat ggtatcgata gccccttgtt cgagtagttt
     4981 ttggcgaatc ttgccttctg cagcaccacg gaaaaggaca ccgtgtggta agacaatcgc
     5041 catagttcct gtatttttta aatgatagaa accatgaagt aaaaaggcaa agtcagcttt
     5101 tgattttggt gctaatacac cataacttga aaaccgtgga tctgttaaga aaccagcagt
     5161 cgctgaccat ttcaaagaat aaggtgggtt cattaacact ccatcaaagt ttgttggttc
     5221 atctgttggc cagtctgcat ccaaggtatc agcgttactt aagtgttggt tttcgatggc
     5281 aacgccatga agcatcatgt tcatacgagc caagttataa gtagaagtat tgatttcttg
     5341 accatagtaa gagacggtat cggattggtt actatatttc ttagcattta aaaggagtga
     5401 tccagatccc atagcagggt cataaagggt cattcctttt tgatcttccc aacctaaaaa
     5461 gacaatctga gtcatcaagt gagagacagc ttgtggggta tagaactcac ctgctttttt
     5521 tcctgactca ctggcaaatt caccaatcaa gtattcataa gcatcaccta aagtatcccc
     5581 atctactgcc tcaaagtcaa tttcatttaa tgttttcatg acattagaaa tggtttgatt
     5641 ttgtttttga ggagtagagc ctaatttttt agagtagagg tcaatatctt caaataagtt
     5701 ttcaaagtct tcaccacttt gttcaatatc gcgaaaacct tgagctaatg attctaattg
     5761 gaaagtattg tgataaacat cttggatgag tttttcaaag gtcagtgtag gttcgataaa
     5821 gtaacctaaa tcaccagtaa caacagaaat gaggtcatct tttaggcctt catcttgata
     5881 ggcattttca aagatttttt gagcatctgt aaaggtatta aagtgttctt ctaaattatc
     5941 acaaacagca aagagtaatt tatcagataa atgtttgtaa aagatgagtc caagaagata
     6001 gtttttatag tcattggcat ccatttggcc acgtaattga tcggccgaat gccatagtgc
     6061 ttgccgtagt gaagttgttt tctctgccat gtgcgtcctt tcttatacga ataaacgatt
     6121 gagtaatgtt tgtttgagtg ctttgagttc tgttagtttt tcttcagatt gagcaatttg
     6181 ttggtctaaa gtttggaaga aattaccaat ggcttcttgt tctgagaggg aagggatttg
     6241 aattttagca tatttgatat cactagagct aatgctatca aaagttgaac ctgtactaat
     6301 tcttttccaa taaccaattt ctttcaagta ttttaatatt tgaaagataa attcattacc
     6361 ttttatagca gcaactccac gcccaataat aacatgataa tttgtctttc caacatcacc
     6421 aactggagcc ctaacactaa gaataatatc acctttgtca gcttgttttg taatttgtgt
     6481 tgtccagaca cgcggaaaaa catatccatt ttttatatcg gcatttcctt gtactagaat
     6541 ataatcagaa gggtttgtag tataattttg acttgatgga gattggccca ttgtaatttg
     6601 aacaatatca cctagttcct tctcttccca ctcaccatca aaaccttgta aacggatttc
     6661 agggactttt tgtccttgag ctgggaacat ctttctgagg aaggtttgct tttgttcttt
     6721 aaggattgct agcttttgcc tctgtaactg aattaactga tcaaccgttt ggaagagttc
     6781 gccaatggct tcttgttcag ggagggaggg gagattgata acttgatttc gaattatttc
     6841 agaattcaga ttcacttggc ttcctggttg accatattta ttccaatatg gtctgaacat
     6901 atctaaccac tgaaacataa attcacggtt gaatttagga tctaaaaaca caagaaatcc
     6961 atcgtgtact ccagttttaa cataattgat aactggttta cctactgtag ctgcaatact
     7021 taatagtaaa tgtggatcct ttaatactct agtcttttct tgaccaagct cagatattct
     7081 ttgttgtaaa taagttatac gaccctcttg ttcagtaaca tcagaaattc ttaaccaacc
     7141 tatatcactt ttggcatcaa accattttgg atcttgtatc ggtctaggac tggcaccacg
     7201 aactatatta gaaatttctc ccagcttttt ctcttcccac tccccttcaa aactgtcaaa
     7261 gcgatattga ggccgtttag attttgtcat ctctttcctt tcctagtgcc cttttaaggg
     7321 ttggatttga tctctaatga attgaactaa ctcccgttca aattggcttt tgtatttgag
     7381 tttattcatg gccgagtcac cttgtttttc tttataggct tggtagtcta gggattcttt
     7441 taaggttgat atgcccactt gtttggtaga gttagcacta tgataattag tcgccacaaa
     7501 ggctaatttg tcaggatctg ccttccactg gtccgcaaag tgtttgatgg ccctttggat
     7561 cttatcacca atgaggttat ccaactcata agcaatgctt ttcccttcat aggctttggg
     7621 ttctttttgg atatcttgcc ataactcagc tagtgagtca gccatagcag ggtttgattt
     7681 tgccaaatct tggatgtatt gatccatggg attgtcattg agcctttctt gaagagcttc
     7741 ttgttcttga tcgacaaagg cttgaattaa ggtcaagata tagtgatagt tgatatcatc
     7801 catctgaaca ctttctagct catagtcgat attgatctct gggatggctt cgtcatcttc
     7861 tcttcgcttt cgtatttctg caatgacatt ttggtaagtg cctttataag tatcaatcac
     7921 ttcatctgat aacccaacct cactcaatag tgtttcatta aagtcactat agacctgtac
     7981 agatgcatag agcttatcaa acgcttgaaa ggctttggcg tattgtttga gaaaagctgt
     8041 ctgtgcgctc tcaatagttg ggaaagcgtc tggatcagga actatatttt ttaatactgt
     8101 tactttttca aagaatcttg ctttttcttc ttcccaagaa ggcgctaaaa cttcactttg
     8161 accaccattt gagtataggc taagagccgt atcaacagct tctttaaaac gaagtggtgt
     8221 ttggaaagtc acaacctgac cgtaatgttt tctactttca aagatacggt tggttcgtga
     8281 gaaagcttga ataatgtgct gaggtttcat aggctggcga tcgatgaaga tggttgataa
     8341 acaaggcgca tcaaagcctg ttaagagacg gtcaaccaca atcacgaggt ctaattgttc
     8401 atgacggtct ttgaatttat cttttttacg ggctaagcga tcatttaaat ctctgttata
     8461 gccttgtaag ttatcgatgg taaagttagt gccaaagagg tgattatagt cttctagatt
     8521 tttggtcatt ttatcttgtc ggctgataga cgcattgtca ttttcagtga tagaataagt
     8581 aatagctacc tttggaaagt ctggtagttt ttctttgacc ttcttagaaa tgactaaatc
     8641 cgtttcacca gccttaactt tcttcatcag atcataatag gcttgggcac gagcaatact
     8701 cttaacggtt agtaaacctt cgaatgtctg accaattcca ttattaaaac caagtttctt
     8761 gcgtgattga ttaatgatac tatctaagac agctaacata tgttcttcat gatcataagc
     8821 ttcttccgga atactgtctt caggcatatc aggaatggtt gtcttatact caacttgaaa
     8881 gcctagaacc gctttatcat gaatggcttc tttaacggtg tattgatgga gacatttgcc
     8941 gtattgctgt tccgttgttt gggctaaatc acctaattga gcacgcttat tttccacaaa
     9001 gataggagtg ccggtaaagc cataccagcg actgttacga aaagtattcg tgagataacg
     9061 ttgacgttcc ggtgtgacag cacggtggca ttcgtccaca acaaagacaa catttaagtg
     9121 tgcaagacgc tcttttagtt tcttgaattt tggagtgtca taactttcca tctgactgat
     9181 catggcattg agtttttgaa tggtggtggc cacaacacga cgatcactgg attctaaatt
     9241 tttgatgagt tgtctcgtat cttctgtctc atcgacatca aagatatcat tttgcgcata
     9301 ggattgaaaa gcagaagcgg tctgattatc taaatccttt cggtcaatga caaagatgga
     9361 tttttcaacg gccggtattt gaaggatatt gcgagccact ttataggaag ttaaggtttt
     9421 tccagaacct gttgtgtgcc agatatagcc agacttgcgg tgacgactcg cttcagcgac
     9481 ggcttcgatt gcatgaatct gataaggacg aaggagaatt agtgcttttt tatcatcatc
     9541 aatgacagag taagtcatga ccatttggtg agcacgaggg atagatagga cttctttggc
     9601 aaaggcaaag agatcttttt gtggtttgtt gttttgatct acccattggg tcaagaagtt
     9661 agggtttaat ttattttctt tagctgcagc gatatacctt gtatctgttt tatttgagac
     9721 cacaaacatt tgtaaggttg aaaagatacc tctaaactgg ccttctttat catacttttt
     9781 gacttggtta aaagcttcaa tgcattgatg attctgagat tttaattcaa tttggatcat
     9841 aggtaagcca ttgatgagaa gtgtcacatc acctcgtcta tcacgagaac cagagaaagc
     9901 aacttgattg gcaatctcat aaacagaagt tccaccagcc acattgtctg ctttaacgac
     9961 ttctaaacga atcgttccta gttttgcatc ttcgcgttgc acttgtactt tagcaatgcc
    10021 gttttcacca gctaaccatt tagccgcttc atagtaattg acaaagttaa gttgattctt
    10081 aatctgctct ttttcactag ctgttaaagg ctcctcattc agatattgcg tgttattttg
    10141 cgctaagatc ttaaagaaat tatcccataa agcatcttca gtttttaatt ctttacgata
    10201 tgtccattga ctttcacctg tttctaagag atggatcaac tctttttcaa gttcaagttc
    10261 cgttttagtt tgatttccca tttttaatcc ccattcgaca tgatatagta atattatatc
    10321 attggcggat cctttttaga atggcaaagc tattgaaacc ttccaaacag tctttttttg
    10381 attagttgaa tgcttaagat cctagcaact aaacaaagct atgactatgt aaatgcaatc
    10441 gagaaagttc ttgtattttt gagtttgctt gacaataatt taaggcgaag aaagtaataa
    10501 gacaacacta gtaaaaaggt cgagttctca aaatagataa aaaacttaag acagatctag
    10561 cttgactatt aatagggttt taaaggacga taatctgcta caatatacag aaaaggaatt
    10621 tattgaagat atgaaaattt tggtagccat agattctttt aagggatcgg taacgtctcc
    10681 agaacttaac actagtgtag ctcaagccct tctttctgtc gataagcagt tagttattga
    10741 aacaagagct atcgctgatg gaggagaagg aagtttagca gccctctcac aaaccgtggc
    10801 ggggaggtgg catcaagtaa aaaccattga tctattaaga cgcccgatta aagtcgctta
    10861 ttatcgtcac gcaaagcaag cttttattga atctgcgagt attattggta ttgataagat
    10921 cacccccaat tcagtaacct atgcacaagc cacttcctat ggtttgggtt tggcagttaa
    10981 agatgccatt caaaaaggag ctactcaaat cgaaatcatg ctaggaggaa caggcacttc
    11041 tgatggtggc aaagggtttt tggaaagttt aaactatgat ttcatgacag gaagatctta
    11101 tcttgatact ttagcatcac ctgttacgct attagggctg actgatgtga ccaatccata
    11161 tcatggccct caaggatttg ctgcggtctt tggccctcaa aaaggtggga gtcttagtca
    11221 aattgaagaa actgatcaaa ttgcaagtaa ctttgctaaa aaagtttttt accaaaaaac
    11281 cattgattta cagacaatac caggaagtgg agcagctgga ggattaggag gtgccattgt
    11341 cctattagga ggcaccttaa ctagtggttt tagcaggatt gcagagctac taaatctgga
    11401 taattccctt cagtcctgtg atttagttat tactggagaa ggatgcctgg atacacaatc
    11461 acaatctggc aaggtacctg ttgcgattgc aagaatggct aaaaaatatc aagttccaac
    11521 gattgctcta tgtggttctg taaagattga gacaggacta gcagcagaag actttttggc
    11581 tgttttttca atacaacagc agccaatttc cttagaagca gcgatagata aaacaacaac
    11641 actttccaat atcaaaatat tagtagctaa ccttatgcta ttgatagccc agtttaataa
    11701 gtaaactcat ctattttcga ttgtgtagca ttcatttggc ggttaaaagt aacctatgaa
    11761 gaaggagacg tacgagctaa ctcattagca tagtatgaaa aacagaaaca ttttgtaaaa
    11821 aaaagagttg acaatgacag taaagatatc gtatactaat aaagctgtca gagaggttgc
    11881 tgtaacacac ttattgaaaa aagatgaaaa agtagttgac aggctatgag aaacctgata
    11941 gaataaagaa gttgtctctt aggagacgtt aagacctttg agaactgaat aagacgaacc
    12001 aaacgtgagg gtgatatgga gacatattac ccgtcaagaa acgagaaata aatctgtcag
    12061 cgacagaagg aacgagtaag ttcaaacgca aattaaagag agtttgatcc tggctcagga
    12121 cgaacgctgg cggcgtgcct aatacatgca agtagaacgc tgagaactgg tgcttgcacc
    12181 ggttcaagga gttgcgaacg ggtgagtaac gcgtaggtaa cctacctcat agcgggggat
    12241 aactattgga aacgatagct aataccgcat aagagagact aacgcatgtt agtaatttaa
    12301 aaggggcaat tgctccacta tgagatggac ctgcgttgta ttagctagtt ggtgaggtaa
    12361 aggctcacca aggcgacgat acatagccga cctgagaggg tgatcggcca cactgggact
    12421 gagacacggc ccagactcct acgggaggca gcagtaggga atcttcggca atgggggcaa
    12481 ccctgaccga gcaacgccgc gtgagtgaag aaggttttcg gatcgtaaag ctctgttgtt
    12541 agagaagaat gatggtggga gtggaaaatc caccaagtga cggtaactaa ccagaaaggg
    12601 acggctaact acgtgccagc agccgcggta atacgtaggt cccgagcgtt gtccggattt
    12661 attgggcgta aagcgagcgc aggcggtttt ttaagtctga agttaaaggc attggctcaa
    12721 ccaatgtacg ctttggaaac tggagaactt gagtgcagaa ggggagagtg gaattccatg
    12781 tgtagcggtg aaatgcgtag atatatggag gaacaccggt ggcgaaagcg gctctctggt
    12841 ctgtaactga cgctgaggct cgaaagcgtg gggagcaaac aggattagat accctggtag
    12901 tccacgccgt aaacgatgag tgctaggtgt taggcccttt ccggggctta gtgccggagc
    12961 taacgcatta agcactccgc ctggggagta cgaccgcaag gttgaaactc aaaggaattg
    13021 acgggggccc gcacaagcgg tggagcatgt ggtttaattc gaagcaacgc gaagaacctt
    13081 accaggtctt gacatcccga tgcccgctct agagatagag ttttacttcg gtacatcggt
    13141 gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga tgttgggtta agtcccgcaa
    13201 cgagcgcaac ccctattgtt agttgccatc attaagttgg gcactctagc gag
//
LOCUS       DATWVB010000042        13164 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.042, whole genome shotgun sequence.
ACCESSION   DATWVB010000042 DATWVB010000000
VERSION     DATWVB010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13164
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.042"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            517..1044
                     /locus_tag="VCX65_001444"
     CDS             517..1044
                     /locus_tag="VCX65_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEP5053899.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            1044..2162
                     /gene="yqeH"
                     /locus_tag="VCX65_001445"
     CDS             1044..2162
                     /gene="yqeH"
                     /locus_tag="VCX65_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEP5053900.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIERINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLSRFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPGKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            2188..2496
                     /gene="yhbY"
                     /locus_tag="VCX65_001446"
     CDS             2188..2496
                     /gene="yhbY"
                     /locus_tag="VCX65_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEP5053901.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2565..3197
                     /locus_tag="VCX65_001447"
     CDS             2565..3197
                     /locus_tag="VCX65_001447"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEP5053902.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDFYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ"
     gene            3194..3787
                     /gene="yqeK"
                     /locus_tag="VCX65_001448"
     CDS             3194..3787
                     /gene="yqeK"
                     /locus_tag="VCX65_001448"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEP5053903.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3811..4164
                     /gene="rsfS"
                     /locus_tag="VCX65_001449"
     CDS             3811..4164
                     /gene="rsfS"
                     /locus_tag="VCX65_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEP5053904.1"
                     /translation="MKKEELLKIVVEATDEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWYEAPAVALDAYLA"
     gene            4212..4955
                     /locus_tag="VCX65_001450"
     CDS             4212..4955
                     /locus_tag="VCX65_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP5053905.1"
                     /translation="MKHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTKTSKRWFFVAYK"
     gene            5209..6315
                     /locus_tag="VCX65_001451"
     CDS             5209..6315
                     /locus_tag="VCX65_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEP5053906.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTEDVID
                     YQKLIKVYEKKSKQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6797..7513
                     /locus_tag="VCX65_001452"
     CDS             6797..7513
                     /locus_tag="VCX65_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP5053907.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            7716..8558
                     /locus_tag="VCX65_001453"
     CDS             7716..8558
                     /locus_tag="VCX65_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP5053908.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKTAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYRVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8885..9730
                     /locus_tag="VCX65_001454"
     CDS             8885..9730
                     /locus_tag="VCX65_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEP5053909.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGAQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            9980..11044
                     /locus_tag="VCX65_001455"
     CDS             9980..11044
                     /locus_tag="VCX65_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEP5053910.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSADALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTKKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            11045..11737
                     /locus_tag="VCX65_001456"
     CDS             11045..11737
                     /locus_tag="VCX65_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053911.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(11791..13161)
                     /gene="brnQ"
                     /locus_tag="VCX65_001457"
     CDS             complement(11791..13161)
                     /gene="brnQ"
                     /locus_tag="VCX65_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEP5053912.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VIASFVHPAGNYGDAFNAGVGVNNAFKDFPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEVTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFSDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTGLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLIL
                     SKTKKS"
BASE COUNT         4331 a         2072 c         2747 g         4014 t
ORIGIN      
        1 gtaatcattt tttgatttac agttattatc atgtgttatc tggcgactgt cctgtttaca
       61 agtaagttca caagtatggg ataaaatagt ataaactata gtaaatactg aatagtcata
      121 gaaaaatatc ggcataggtc agaaaagctg atatgtttaa tactttttgc ggatatctac
      181 tgtatttaaa tgtatttgat atccttgtca aggatatacg tctaaacaag ttcaaaacga
      241 aatcatttgt gattatctta tcaggagttg actcttgata agatttttgt atatcagtac
      301 tgtggtacgt ttagatagct tggcagtgaa tttatagagt gtcaaacaac gagtgttttg
      361 tgttacacta accattagaa gagtctattg ttgagcatat caaggtgtta tcttttcgag
      421 ttgaggtatc atatctagta tatttaacta tggttttaaa tgctatttca aaaaaaatat
      481 gataaaatag aaagtactaa ttattttgga gatgacatga gtatcgatga ttataggccg
      541 acctatatgg tagaggctat ttatgattta agagcaaatg atttgttgcg tcatggtatt
      601 acggctgttt tagtggattt agataatacc ttaattgcat ggaataatcc tgatggcaca
      661 ccagaggttc gcgcttggct tgatgaaatg actatcgcgg atattagcgt ggttgttgtt
      721 tcaaataata aacattctcg tgttgagcgt gccgtttcac gctttggtgt tgactttatt
      781 agccgggctt tgaagccatt tgcttatggt attgaaaaag ccattgctcg ttatggattt
      841 gatcgcaacg aggttatcat ggttggagat cagctaatga ctgatatcag agctagtcat
      901 agagctggaa taaaatcagt tttagtcaaa ccacttgttg cttctgatgc ttggaatact
      961 aaaattaacc gctggcgtga acgccgtgtg atggcaaaat tagaagagaa atatggtaaa
     1021 ttatcatatc aaaaaggaat ttaatggaag aattattttg tataggctgt ggtatccaga
     1081 ttcaaactga agacaaagaa aaagctggtt ttacgccagc tgctgctttg aaaaagggta
     1141 tggaaacagg agaactctat tgtcagcgct gctttagatt gaggcattat aatgaaatta
     1201 cagatgtcca tattaccgat gatgaatttt taagacttct tcacgaagtg ggtgatagtg
     1261 atgctcttgt ggttaatgtg attgatattt ttgactttaa tggttctatt attccaggtc
     1321 tatctcgctt tatttctggt aatgatgtct tactggttgg gaataaaaaa gatattttgc
     1381 caaagtctgt taaggatggt aaagttactc aatggttgac ggaacgtgca cacgaagaag
     1441 gtcttcgccc tttagacgtt atgttaacga gcgctcaaaa taaatatgcg attaaagact
     1501 tgattgagcg tatcaatgag ttacgtaatg gtcgagatgt ttatgttgtg ggggtcacta
     1561 atgttggtaa atcgacctta attaatgcca ttattcaaga aattacaggg gataaagatg
     1621 tgattacgac gtcccgcttc cctggaacga cccttgataa aattgaaatc ccactggatg
     1681 acggtagctt catatttgat acgccaggta ttattcatcg tcatcaaatg gctcattatt
     1741 tatcccctaa agagctaaaa atagtgagtc ctaagaagga aatcaagcct aagacgtatc
     1801 aattaaaccc agaacaaact ctctttttag gtggtttgtc tcgctttgac tttatcaatg
     1861 gggagcgtca agggtttaca gctttttttg acaatcaact agaattacat cgtacaaaat
     1921 tagctggagc agatgctttt tatgataagc atgttggaac tttgttaact ccgccaggta
     1981 agaaagagtt gacagcattt cctaaattag ttcgtcatga atttacaatt gatcagaaaa
     2041 tggatattgt tttttctggt ctaggatgga ttcgtgttaa tggtcaaaaa gactcaaaag
     2101 caatagttgc tgcatgggct cctgaaggcg tcgctgtcat tgttcgtaaa gcgattattt
     2161 aaaaataaaa aaagaagttg gaaaaaaatg cttacaagta aacaaagagc tttcttaaaa
     2221 tctgaggctc atagcttaaa accgattgta caaattggca aaaatggatt aaatgaccac
     2281 attaagacta gtattcgtca agctttggat gctagagaat tgataaaggt cactttgttg
     2341 caaaatactg atgaagatat tcatgaagta gcagagattt tagaagaaga aattgggtgt
     2401 gatacggttt tgaaaattgg tcgtatcttg attctctata aggtttctgc taagaaagaa
     2461 aaccgcaagt tgtcccctaa agttaaagca atctagtcct tttatttgta tagggactgg
     2521 ttttatgaga cgaggactat tgtcgcgaga attttggaga aagtatggca ttagaattgt
     2581 tgacgccttt tacgaaggtg gaattagagg aagaaaaaaa agaaagcaac cgcaaacaga
     2641 ttgggatttt aggagggaat tttaatccta ttcacaatgc acaccttgtg gttgcagatc
     2701 aagttcgcca gcaattagga ttagatcagg tgctattgat gcctgaatgt aaaccaccgc
     2761 atgtggatgc caaagagact attgatgaga agcatcgtct tcgcatgttg gaattggcta
     2821 ttgaagatgt tgaagggcta gctattgaaa cctgtgaact tgaacgtcag gggatcagct
     2881 atacctatga tacgatgctt tatttgactg agcagcatcc tgatgttgat ttttatttta
     2941 tcatcggagc tgatatggtt gattatttgc caaagtggca ccgtattgat gaactggtca
     3001 aactcgttca atttgttgga gttcaacgtc caaagtataa agctggaacc tcttacccgg
     3061 tcatttgggt agatcttcct ttgatggata tttcttctag tatgattagg gattttatta
     3121 aaaaaggtcg tcagcccaat tatctcttac ctaagcgggt tttagactac attactcaag
     3181 aaggtttgta tcaatgacat atgaagatta tcttccttat agcaggaccg aactgttagc
     3241 aaaaattgca gagcagatga gccctaaacg gtttaaacat gtacttggcg tggaaaaggc
     3301 agccttgtcc ttggcagagt gttatggttg taacccagac aaagcagggt tagcagctct
     3361 tttacatgat tatgccaagg agtgccctga ccaggtcttt ttagacttaa ttgacaagta
     3421 ccaattatct ccagaattag ctaaatggaa taataatgtc tggcatggta tggttggtat
     3481 ttataagatt caagaagacc tagggctaaa agacaaagat atcttgcgag ctattgaaat
     3541 tcacaccgtt ggtgctgctg agatgacctt gctggataag gtcttatacg ttgctgatta
     3601 tattgaagaa ggtcgcattt ttcctttggt tgatgacgct agaaaaatcg cgaagctcga
     3661 tttgaatcag gctgttgcct atgaaacagt gaacactgtc gcttatttag cctcaaaagc
     3721 gcagcctatt ttcccacaaa ctctggatac ctataatgcg ttttgcagct atttaaagga
     3781 atactaatgg ataatgatat gaggaataaa atgaaaaaag aagaactctt aaaaattgtt
     3841 gtggaagcaa ctgatgaaaa gcgtgctaaa gatattttag ccttggattt agaggggtta
     3901 actagtttga ctgattattt tgtgattgcg agtgcaacaa atagtcgtca attagaggct
     3961 attgcggata atatccggga aaaggtaaaa gaggctggtg gagatgctag ccatgttgaa
     4021 ggtaatagcc aagcaggctg ggtcttgctt gatttgaccg atgtggtggt acatcttttt
     4081 ttagaagatg agcgttacca ctataatctt gaaaaattgt ggtatgaagc gcctgctgtg
     4141 gctctagatg cctatttagc ttaatgttac aaagagacct tgtcaatacg acagggtttt
     4201 tgaggatgat aatgaaacat aattatgaaa aatttgcgtc agtttatgat gctgtgatgg
     4261 atgattctct atatgacttg tggacagatt tttcacttcg acatttacca aagtctaagg
     4321 gtcgaaatcg tttgttagag ttggcctgtg gaaccggtat tcagtcagtt cgttttgctc
     4381 aagcaggttt tgatgtgact ggtttagact taagtcaaga catgctggct attgctaaaa
     4441 agcgtgcgca atctgctaaa aagaaaattg attttattca aggtaacatg ctggatttgt
     4501 cacaggtggg gcagtttgat tttgtaacct gctattcgga ttccatttgc tatatgcaag
     4561 acgaagttga tgttggcgat gtttttaaag aagtttatga tgttttagca aacgatggca
     4621 tctttatttt tgatgtgcat tcaacctatc aaacggatga gtgtttccct ggttattcct
     4681 atcatgagaa tgcagatgat tttgcaatgg tttgggatac ctatgctgac gaggctcctc
     4741 actctgttgt tcacgaactc actttcttta tccaagaaga cgatggacgt ttttctcgct
     4801 ttgatgaagt gcatgaggaa cgaacgtatg agttattgac ttatgatatt ttgttggaac
     4861 aagcagggtt caagtcattt aaggtctatg ctgattttga agataaggag ccaactaaga
     4921 ccagcaagcg ttggtttttt gtagcatata aatagaagaa aaaagtagcc tttttagcta
     4981 taggatttaa tgaattatct tgaatgttac ttatatgaaa agagttcatt aggcattaaa
     5041 tgctattatc aaagcttaga agtattggag acattacgat tgacactatg tctgaaggtt
     5101 gctaccaact ttaaagaaag cattttctat tatacgttgt gcttaagcat ttgatttaac
     5161 tcttattagc cctataaaag actatttagt acaatttgag gagattctat gactgttacc
     5221 ggaattatag ctgagtttaa tccgtttcac aatggacaca aatatttgct agaaacagca
     5281 gagggactaa aaattattgc tatgtcagga aattttatgc aaagaggaga gcctgctctt
     5341 attgataaat ggattcgatc agagatggct cttaaaaatg gtgcggatat tgttgtggaa
     5401 ttgccctttt tcgtttcagt tcaatcagca gactattttg ctcaaggagc tattgatatt
     5461 ctttgtcaat taggaattca gcaattagca tttgggacag aggatgtgat tgattatcaa
     5521 aaactgatta aggtctatga gaaaaaatca aagcaaatga ctgcctattt atcgacgctt
     5581 gaagatacac ttagctatcc acaaaaaaca caaaaaatgt gggaaatctt tgctggagtt
     5641 aaattttcag ggcaaacgcc aaatcatatt ttggggttaa gttacgcaaa ggctagcgct
     5701 ggaaagcata tacaactatg tcctatcaag cgtcaagggg ctgcctacca ttcgaaagac
     5761 aaaaatcatc tgctagcttc tgcaagtgcc attagacagc acctgaatga ttgggatttc
     5821 ataagtcatt cagtaccaaa tgcaggttta cttataaaca atccccatat gtcatgggac
     5881 cattattttt cattcttaaa atatcaaatt ctgaaccatt ctgatttaac tagtattttt
     5941 caggtcaatg atgaattggc aagtcgtatt aaaaaagcga taaaagttag tcaaaatatt
     6001 gaccacctag ttgacactgt tgctaccaaa cgctatacaa aagctcgtgt aagacgtatt
     6061 ttaacctaca ttttggttaa tgctaaggaa cctactttac ctaaaggaat tcatattcta
     6121 gggtttacct caaaaggaca agcacattta aaaaaattaa aaaaaagcag gcctctgatt
     6181 actagaattg gagcagaaac ttgggatgag atgacacaaa aagcagacag catctatcaa
     6241 cttgggcatc aggatatccc agaacaaagt tttggaagaa tacctattat aataaaaaat
     6301 gagaggctca attaaactct aattgagttt ttttgggggc ttgactctaa cattacgttg
     6361 atggtttata cttcagttaa tccaatgagg aaattttata acaataatta aaaaagtcag
     6421 tcaaaagata tgctttcgaa gaacaggcta acgtttttac aagattatat cagtaatcat
     6481 tttgacaatt gtagtaatgg aatgttgcca aaatttagaa tgttgtgtgt tatgaatgac
     6541 aagattttaa aggaatacta attaaacggg aggtcgtgaa ccggaagctg ttgtcactca
     6601 agcgccaaaa tctgtctgta acataatatt gatgtatggg aacgcaatta tttggttttt
     6661 attgtgatgc ttaaaacgat tttatatttc tattttacca aagcttttca aagtgctata
     6721 ataagggagt tagagtcaat attagtaacg ttaatgttga caatattcaa taaaatacta
     6781 ttaaaaggag acaaaaatgg gacgtaaatg ggcaaatatt gttgctaaaa aaactgctaa
     6841 agatggagca acatcaaagg tctatgccaa atttggtgtt gaaatttatg tggctgccaa
     6901 acaaggcgag ccagatccag agttaaatac agctcttaaa tttgtcattg atcgtgcaaa
     6961 gcaagcacaa gtgccaaagc atgttattga taaagcgatt gataaagcta aaggaaacac
     7021 agatgaaact ttcgtagagg gacgctatga aggttttggt ccaaatggtt caatgattat
     7081 tgtggatact ttgacatcaa atgttaaccg tacagcggca aatgtacgta cggcttacgg
     7141 taagaacggt ggcaatatgg gagcttcagg atctgtatcc tacttatttg ataaaaaagg
     7201 ggtcatcgtt tttgctggtg atgatgctga cagtgtcttt gaacaattac ttgaagcgga
     7261 tgtagacgta gatgatgttg aagcagaaga gggaacaata acagtttata ccgccccaac
     7321 agatcttcat aaaggtatcc aagcacttcg cgataatggt gtagaagaat tccaagttac
     7381 tgaacttgaa atgattcctc aatcagaagt agtattggaa ggtgatgacc ttgaaacttt
     7441 tgaaaagctt attgatgcac tcgaatcaga tgatgatgtt caaaaagtgt atcataatgt
     7501 agcagatttt taaattgaca tagaataata aaaagagttg aaaactattt cagctctttt
     7561 taagtgatgc ttttataagt aagtaccaag taacatagtc gttgttagaa gataatgaac
     7621 aatagtaaat cagtatcaac ttgataggaa tcaattatta gtgaactcta attaaaaatg
     7681 gtaaactaga cacaagaaca aaaaggagag ataggatgat taaaaaacaa tatttaggaa
     7741 gggcaacaat tgccctagca tcaacccttg tactagcagc ttgtgggtca tcaaaaacag
     7801 ctgagtcagg aaatcagggg agttctaaag aagtcttatt tgcaacggtt ggaacaacag
     7861 ctcccttttc ttatgaaaaa ggtggtcaac taactggcta cgatatcgag gtggctaaag
     7921 cagtctttaa aggatcggat gattacaggg tgtcctttaa aaaaacagaa tggtcttcta
     7981 tctttacagg tttggactca ggaaaatacc aaatgggtgg taacaatatt tcctttacca
     8041 aagagcgttc agctaagtac cttttttctt atccaatcgg atcaacacct tctgttttag
     8101 ttgttccaaa agacagtgat atcaagagct ttgatgatat ccaagggcat acgacacaag
     8161 ttgttcaagg gactacaagt gttgcacagt tagaagactt taataagaaa cacagtgaca
     8221 acccggttac tctaaaattc accaatgaga acattaccca aatgttaacc aatttgagtg
     8281 aaggcaaggc agatttcaag atttttgacg ctccaacggt taacgccatt attaaaaatc
     8341 aagggttaga taatctcaaa acaattgaac tcacctcaac agagcaacca tttatttatt
     8401 ttatctttag tcaagatcaa gagaaattgc aaagctttgt taacaagcgt attaaagagt
     8461 tgactgctga cggaactctt agcaagcttg ccaaagagca ccttggcggt gattacgtgc
     8521 catcagataa agagttgaaa cttcctacag ctaactaaac catctattaa ccagttattc
     8581 atctagaaga ctggtttttc tgatcggaaa caatattata gtttatgagg ttatgttata
     8641 aaaattgcaa atagccttaa tcaaaatgag atgttaaagt gctttttgag aagtgaatat
     8701 tgtaagaagt atgctttggg ttttagtcct caaataccaa gttttttgtt gactaaacaa
     8761 ataaggatgg ttagcatagc atatagttta aaactatggt atatgctagc cattatcaat
     8821 ttgaaaacta tatctaatta agatacaata atgatcgtaa acaaaatgaa tcgaggataa
     8881 cgctatgtct tttaaaaaat ggattggaat agtcggaatc gctttagcat caactgtatt
     8941 ggttgcttgt tctgaaaaac aagatgataa aaacactcta actattggag tgatgacaaa
     9001 aacagaatct gatcaagcga gatgggataa agttgaagaa ttattgaaaa aagacaatat
     9061 cactttgaag tacaaagaat ttacagatta ctcgcaacct aataaggcag ttgctaatgg
     9121 tgaagtcgat attaatgcct tccaacacta taatttctta aataactgga ataaggaaaa
     9181 taaggaacat ttggtggcca ttgctgatac ctatatcagc ccaattaacc ttttctctgg
     9241 aaccagtcaa gatgggaagg ctaaatacaa atcagtagct gatctgccaa atggtgctca
     9301 aattgcagta ccaaatgatg cgaccaatga aagccgtgcc ctctatgtgc tgcaatcagc
     9361 tggcctcatt aaattgaatg tgtctggtga tcaattagca accattgcca atatctcaga
     9421 gaacaaaaag aaattagata tcaaggaatt agatgctagc caaacggcac gtgctttagt
     9481 atctgctgat gcagctgttg tcaataatag ttacgctgtt cctgcaaaaa ttgactacaa
     9541 aacctctctt ttcaaagaaa aagcagatga caattcaaaa caatggatta acattattgc
     9601 aggtcaaaaa gattgggaaa aatcagagaa ggctgatgct attaaaaaac tcatcaaggc
     9661 ctaccaaact gatgaggtga agaaagtcgt ggaaaaaact tcaaatggta tagatgtatc
     9721 cgtatggtaa attttagcca ttgttataac aagagtgtgg tcgtgtttaa aacacatgct
     9781 ttcttgcatg cttgaggaag agtttacgac taatttacct ttagaaagct atttaagacc
     9841 ttttcccttt taggatttag aaaccttggg aagactattg catgttatct taatagtcat
     9901 gattatgcag gcgatgaaaa cattgctatc gtagattact gtcgccatat cgtactaata
     9961 gaggagttat taaaatctta tgaatgaagc aataattcaa ttagatcata ttgatattac
    10021 cttccgtcaa aaaaaacggg ttatcgaagc tgttaaagat gtcacggttc atatcaatca
    10081 aggagatatt tatggcattg ttgggtattc aggtgccggg aaatcaactc ttgtgcgtgt
    10141 gattaacctg ctacaggcac caacaaacgg gaaaatcact gttgatgggg atgtgacctt
    10201 tgaccagggg aaaattcaat tgtcagctga tgcccttcgc caaaaacgac gtgatattgg
    10261 tatgatcttc caacatttca atttgatggc ccaaaaaaca gccaaagaaa atgtagcatt
    10321 tgcgctccgt cattcgtcgt taagtaagac taagaaagaa cataaagtta tcgagctgct
    10381 agaacttgta ggtttatcag agcgagcaga taactaccct gcccagttat cgggtgggca
    10441 aaaacaaagg gtggctattg cgcgtgctct agctaacgat ccaaaaattt tgatttcaga
    10501 tgaggcaaca tcagcactag atccaaaaac cactaaacaa attttggcgc tcttgcaaga
    10561 attaaaccgc aaacttggcc ttaccattgt tatgattact catgaaatgc aaattgttaa
    10621 ggatatttgt aatcgtgttg ctgttatgca aaatggtgtt ttgattgaag aaggttctgt
    10681 ccttgatatc ttttcaaatc caaaagaagc cttgacacag gaatttatca caacagctac
    10741 agggattgat gaggctttag aaaaaattaa ccaacaagac attgttaaac atttgcctgc
    10801 aaatgccctt ctagctcagt tgaaatatgc aggaacttct acggatgagc ctctacttaa
    10861 tagcatttac cgtcaatttg aagtgacagc taatattttg tatggcaata ttgagatttt
    10921 agatcatatt ccagttggtg acatgattgt tgtcttggaa gggcaagctg aaaatattct
    10981 tgcggctgag aaagccttgc atgaagctgg tgttgatgtt agtattttaa agagaggagc
    11041 ctagatgtca cagttaattc aaacttattt gccaaatgtt tatgaactcg gatggtctgg
    11101 agatgctggt tggggcttag cgatttggaa tactttatac atgaccattg tgccttttat
    11161 tgttgggggt gctattggtc tcttattagg cttattatta gttttaacag gaccggacgg
    11221 tgttattgaa aacaaaacga tttgttgggt tattgataaa gttacctcta tttttagagc
    11281 cattcctttt gttattttga ttgctatttt agctagcttt acctatttgc ttttaagaac
    11341 aactttagga gcaacagcgg ccttggtacc tttaaccttt gcgacttttc ctttttatgc
    11401 ccgtcaggtc caagttgttt tttcagaatt agacaagggt gttattgaag cagcgcaagc
    11461 ttcaggtgct actttctggg atattgtcaa agtgtatctc agtgaaggtt taccagatct
    11521 tattcgtgtt tctacagtca ccttaatttc tttagttggg gaaactgcca tggcaggagc
    11581 tatcggtgct ggaggattag gaaatgtagc gatttcttat ggttataatc gttttaacaa
    11641 tgatgtgact tgggtagcga ctattattat tcttttaatt atttttgcta tccaatttat
    11701 tggtgatagc ttgactagaa ggtttagtca taaataaacg aaacaacacc ctaagttttt
    11761 acttagggtg ttgttgttta gatgatgtca ttagcttttc ttcgttttac ttagtataag
    11821 ccctattaaa aaaccaatag cagcaaagat aatccatccc attgagaatt gccctagtgg
    11881 aacagttttt tggaaaaaag ttacaacggc ttctggtaaa tgaaataatc cagtcatttg
    11941 tgatagtgtt aggagtgcat caaatatggc aggaataaag gttagaccaa ttgtagttcg
    12001 atagacaata ggatcattat tgaagcattt ttgtgccaaa acaaggaaaa ttaaatcgac
    12061 tgttaatggg tataaaagga ataaaacagg agctgaccag ttgataataa ctgataaacc
    12121 accaaaataa aagaaagctg atagtaaagt aaagatagtt gcccaagcaa tatgagataa
    12181 agcaggcact aatttatgga agtattcagc acttgacgtg attaagcctg ttgaagtggt
    12241 tagacaggcc aggaaaatca caacagctag aaatgcttgt ccgatgccac ctaggtaaaa
    12301 acgagaagca tgacttaaga tttgaccgcc attaactgga ttaccatgaa gggtaaagct
    12361 gccatcacta aaaggaaata atgattgtga tgttgctcca atacgaccga caaagatata
    12421 gacaagtgct aatagcaaaa tggcaatagc cccagaaata agtgttattt tggtcacttc
    12481 tttgtccgtc ttagcgccaa attgtttggt agcctcaatg actaaaatag caaaaacaag
    12541 agaagctagt gcatccatag tgccataacc ttgaattaat cctgctataa aaggaaaatc
    12601 tttaaaggca ttattaacac cgaccccagc gttaaaagca tcaccgtaat ttccagcagg
    12661 atggacaaag gacgcgataa ccaaaataga aataacaact aacaacgttg gcgttaaaaa
    12721 ttttccgata ttttcagcta gcttactagg tttgatagca aggaagtagg acagaccaaa
    12781 aaatagtata gcataaatag ctttattggt tgtattatct cctaagatag gagcgatacc
    12841 gactgaaaaa gaagtggctc ctgttcttgg aatagcaaaa aatggaccaa tagataaata
    12901 caaaatggaa gaatagaaga ttgcatacca tttagagatg gggcgtgcca aactttcaac
    12961 atcgcctgat ccagatttag caacagcaat gacaccgagt aaaggcaagg agacaccagt
    13021 taaacaaaaa ccaatgatag accatagaat ctgatgacct gagtagatgc ctaaaaaagc
    13081 tgggtaaatg aggtttgctg ctccaaaaaa tagtgcaaat agcatgaatc caatgacgat
    13141 atatacattt ttttgtttca ttta
//
LOCUS       DATWVB010000043        13057 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.043, whole genome shotgun sequence.
ACCESSION   DATWVB010000043 DATWVB010000000
VERSION     DATWVB010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13057
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.043"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(25..1293)
                     /locus_tag="VCX65_001458"
     CDS             complement(25..1293)
                     /locus_tag="VCX65_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEP5053913.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYNTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPYFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIIT
                     GKKRYLSIAINQQIQSKLNSLIKNTCGKSN"
     gene            1383..2249
                     /locus_tag="VCX65_001459"
     CDS             1383..2249
                     /locus_tag="VCX65_001459"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEP5053914.1"
                     /translation="MKRIIVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQSPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            2227..2784
                     /locus_tag="VCX65_001460"
     CDS             2227..2784
                     /locus_tag="VCX65_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP5053915.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRIPIGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            2918..4462
                     /locus_tag="VCX65_001461"
     CDS             2918..4462
                     /locus_tag="VCX65_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEP5053916.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
     gene            4829..6052
                     /locus_tag="VCX65_001462"
     CDS             4829..6052
                     /locus_tag="VCX65_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEP5053917.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWQN
                     ERIGIYKEEKQVASLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVAFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLNLINQDITRTQAHQKKRLKKL
                     EDQKASFERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPKVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
     gene            complement(6094..7656)
                     /gene="guaA"
                     /locus_tag="VCX65_001463"
     CDS             complement(6094..7656)
                     /gene="guaA"
                     /locus_tag="VCX65_001463"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEP5053918.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7823..9256
                     /locus_tag="VCX65_001464"
     CDS             7823..9256
                     /locus_tag="VCX65_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053919.1"
                     /translation="MLRKKRILGLFRPVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKEPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKRYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            9339..10037
                     /locus_tag="VCX65_001465"
     CDS             9339..10037
                     /locus_tag="VCX65_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP5053920.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            10126..10467
                     /locus_tag="VCX65_001466"
     CDS             10126..10467
                     /locus_tag="VCX65_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEP5053921.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            10482..12044
                     /gene="ffh"
                     /locus_tag="VCX65_001467"
     CDS             10482..12044
                     /gene="ffh"
                     /locus_tag="VCX65_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEP5053922.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENRNDYVLIDTAGRLQIDEKLMEELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQVFGKGFKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(12179..12877)
                     /locus_tag="VCX65_001468"
     CDS             complement(12179..12877)
                     /locus_tag="VCX65_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5053923.1"
                     /translation="MFSGHQLKTARLSKGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
BASE COUNT         4312 a         2183 c         2496 g         4066 t
ORIGIN      
        1 ttatattaat ggtacgaaga aaagttagtt gctctttcca caagtatttt tgattagcga
       61 gtttaatttg ctttgtattt gttgattgat agcaatagag agatagcgct tttttccagt
      121 tattattatt ctatcagatt tatctaatgt aaagtttcta taagagtctg atgtcgtgta
      181 atcaatcact aaatgagtag gggttagttg atagtgaata tcagggcaat tttgttttaa
      241 aaagagagcc aattgacgtt cccgctgttt tagataacgc ttaataaagc gaagattttt
      301 ttgaaacatc ccattttcta aataaagagc taatgctttt tgcattagta agttcgtgtc
      361 taaatcaatc agtgattttt gggttaaaaa ataaggtttt aaacctgacg gtaaaactag
      421 agctccgata cggagtgcag gaaaaacact cattgaaaaa gattttaggt agatgattcg
      481 gtgatgagtg tcataataat gaattggtgg ctctttaagt ttcacaaaat ctcctaaata
      541 atcatcttct aaaatataaa cctggtatcg ttgtgctaga cgaacaatag cttccttttc
      601 cttagtgtta taagaaagtc ccagaggatg tgaaaatcgt gaaatcgtgt aaaaaaattt
      661 aatatcgcca gtttgaaata aagattctaa gagttctaaa tcaaggccat taaagtgtct
      721 agagatagtt tgatagggta atcctaactg agcaacaata gcttccatcc gatgataagt
      781 aggcttttca aggagaattg ttttgcccgc attaggaaaa ggcatttgtg ataaaatata
      841 aagcgcttgt tgcgtcccag aggtgattaa tagttggtct ttgttactgt aaacactatt
      901 ttcagctaag taaagaagca aagcttccct tagttcttct agtccttcgg ttttgtgata
      961 ataatgaaag aggtatttgt ctttagcact taaagcctca tttaagcaga gtcggaaatc
     1021 ttcataagcc atattattat aatcttcaag acttagatta agaacattat cgggcatgct
     1081 tacgttaccc aaaacataat aaccactttt aggaacagca taaattaagt gacgatattt
     1141 taattctaaa agagcccgct gaacagtatc tttgctacaa tgataaacct tacttaatac
     1201 cctaattgaa ggtagcttgt cccctttttt tagtcgctgt ttctggatat cttgttcgat
     1261 attggaaatg attgtttgat attttgttgt cataaattgt ccccatacag ttaagtgtta
     1321 taactattgt atcttatgcc tctttttctt acaatagtta ttatagaaaa gaggtaatag
     1381 ctatgaaacg gattattgtg gcaaatgatc tggttggtgt tggtaaggta gctttgtctg
     1441 ctagtattcc tttaatggct tcttgtttgt tagagcaagt tttattacca acttgccttt
     1501 tatcaagcca tactggcgga ggacagagcc ctgtgaagca tactacatca agtatattag
     1561 acgttttttt aacagattgg gacaacaaaa gaattaagtt tgacggcatc tttataggtt
     1621 attttacgac aacaagagat gggcaaaagc tactagaatg gctttcaaga aagcaacttc
     1681 ccttaatttt agatccaatt atggcagata atggaaaact ttatcaaggc ttcagtcaaa
     1741 aacatataga gattatgata aaacttactc aaaaagctga gcttgtttta cctaatatta
     1801 gtgaggcttg tctattaaca caaacagctt atttagcaaa aaattatgat gaagaagata
     1861 ttagacaggt ggctagaaaa ttagctaagc ttggacctaa acaggttgtc attagcggaa
     1921 tctcttttga ggagggcagc attggttttg cttactatca gtcagattca gatcaattaa
     1981 cattccattt tgggaagcaa ttcccttacc atttctatgg tacaggagat atagcatcag
     2041 ctattataac agcaggattc tattatcagc taccactaac acaaattcta gatcttgttg
     2101 tttcatttct tgaaaaagta ttgcaaaata cccttacatt aaaaagagat ttaatcttag
     2161 gtgttgctta tgaatctcat ttaaattact taactaaatc gtttaaaaag ttgttggagg
     2221 aaaaaaatgt catctcaaaa attagctaat tatattgaat tgagtatgta tgccgcttta
     2281 atttttattt cagtacaagt gttgcgtatc cctatcggta tgcagtttat tcatcttggc
     2341 aatgcattag ttgttattgc agtcttgatc tatggtagta aaaaaggagc tctagttgct
     2401 agtcttggtt tagggatctt tgatgttttg aacggctatg cttcagtcgt ttggataact
     2461 atcttagaat ccttggctat ttgtttaatt ttgcatttgg tatatgaaag agctatgcaa
     2521 tctagtaaaa aaccaaaagc cattataaca ataacagtta ttgctgcatt gtcaaaatta
     2581 actattaacc ttataaaata cttactgtta gcttatatag gtactcagct accactttcg
     2641 gtatcttttt gggtagctct tggaaaaatt ggtggtagtt tcggaacatc ttttgtgact
     2701 ttagttgctg ttcctctttt gtatcctgtt atcaaaaact taaaagaaaa ggttacaatc
     2761 ggacaagcaa aaagaggttt ttgatacaag taccttatcg ataaaaaagc aaggtacact
     2821 ttcagtcaaa tattgacaaa aggttacaat tttgccataa tgaaataact ataaagccgt
     2881 tttgacggct tttttgatga cagttaagga agaaacgatg agtattttag aagttaagca
     2941 gttgagtcac ggttttgggg atcgggctat ttttgaaaat gtgtcatttc gcctcttaaa
     3001 aggtgaacat attggactag ttggagcaaa tggtgaagga aaatcaacct ttatgagtat
     3061 agtcacagga catttacagc ctgatgaagg aaaagtagag tggtcgaagt atgtcactgc
     3121 aggttacctg gatcaacata cagtgttgga atcaggacaa accgttcgtg atgtcttgcg
     3181 aactgctttt gatgagttat ttaagaccga gaatcgtatt aatgagattt acgcgtcaat
     3241 ggcagatgat aaagctgata ttgctgtttt gatggaagaa gtaggtgagc ttcaagatcg
     3301 tttagaaagt cgtgatttct atactttgga tgctaagatt gatgaagtag cgcgtgcgct
     3361 tggtgttatg gattttggaa tggagtcaga tgttacatcc ttatcaggtg ggcaacgaac
     3421 aaaggtttta ttagccaaat tactattaga aaaacctgat attctgctat tagatgaacc
     3481 aactaaccat ttggatgctg agcatattga atggttaaaa cgctatttac aacattatga
     3541 aaatgctttt gtgttgattt cgcatgatat ttctttctta aatgatgtga ttaatattgt
     3601 ttaccatgtt gaaaatcaaa gtttagttcg ctatactggg gattattacc aatttcaagc
     3661 tgtttatgag atgaaacaat ctcaacttga agcagcctat gaacgtcaac aaaaagagat
     3721 tgctaacttg caggattttg tcaaccgaaa taaggctcgg gtagcgacac gtaacatggc
     3781 aatgtctcgc caaaaaaaac ttgataagat ggatataatt gaacttcaag ctgagaaacc
     3841 aaaaccaaat tttgaattta agcaagctag aactcccagt cgattcattt ttcaaacaaa
     3901 aaatcttgtg attggttatg attacccatt gaccaaagaa cccttaaata taacgtttga
     3961 aagaaaccaa aaaattgcta ttgttggggc caacggtatt ggaaaatcta ctttgctaaa
     4021 aagtttatta ggtgttatcg agcctttaga aggtcatatt gtcacagggg attttttaga
     4081 agttggctac tttgaacaag aagtgacagg tgttaaccga caaactccgc tagaagtagt
     4141 ttgggatgct tttcctgcct taaatcaggc agaagttcga gcggcactag ctcgttgcgg
     4201 actaacatca aaacatattg aaagtcaaat tcaagtactt tcgggtggtg aacaagcaaa
     4261 agttcgtttt tgtttgttga tgaatcgtga aaataacgtg cttattttag acgaaccaac
     4321 aaatcatctt gatattgatg ctaaaaatga gctcaaacgt gctttaaaag catataaggg
     4381 ttctatttta atggtttgtc atgaacctga tttctacaat gggtgggtaa ccgatacttg
     4441 ggattttagt aagttaacct aaactattcc ttaatttttt acacaggaat tactaaaatc
     4501 agtaaagata tagaataaat actgctagat atgtgatggt ttaggtaact gatcaccaac
     4561 caaaaaagat gtgactacat ctttttttta tctaatggaa tggtgtaaag tcgtttaata
     4621 atagcttatt ttttgatgat cagttgttca tgaaattgtt ggtgattaac aagtcattta
     4681 agatacaaac gttattacta aaaagtgatt caaatagttt ccctattttt ttatgttttt
     4741 ttaaaattta ttacgaataa atagataaag acagtgaaga tacttagtaa gtacatctgc
     4801 taagattacg aatagatggg gacaataaat gacgaattta acgttttatg caaaaatcgg
     4861 tatttcagaa gaagagcatg actcttttgt taaagaacat cagcaaatta gcgttttaca
     4921 aggtagtgat tgggcaaaaa tcaaaaatca atggcagaat gagcgaattg gtatctataa
     4981 agaggaaaag caggttgcct ctttatcact tttgattaag ctattgccac ttggaagaag
     5041 cattatttat attccaagag ggccagtcat ggattatctt gaccgtgatt tggtggcatt
     5101 taccatgaaa acactaaagg attatggtaa aactaaaaag gccctcttta tcaaatatga
     5161 tccagctatc ctgttaaaac aatacgcact gggacaggaa gaagaagaaa aacctttagc
     5221 tttagcagct attaagaatc tccaagaagc tggtgttcat tggactggtt taacaatgga
     5281 gattgcagat agtatccaac ctcgtttcca agctaatatt tacactcaag aaaaccttga
     5341 gatgcaattt cctaagcata ccagacgttt aataaaagat gctaagcagc gtggtgtaga
     5401 aacatatcgt gccagtcaat cagaacttca caaattttcc aagattgtct ccttaacaga
     5461 aaaacgtaaa aatatttctt tgcgtaacga agcttacttt caaaagttga tgactactta
     5521 tggggataag gcctacttac atctagcaaa agtgaatatt cctcaaaaac tagatcaata
     5581 ccgccagcaa ttaaatctta ttaaccaaga tattactcgc acccaagctc atcaaaagaa
     5641 gcgtttaaaa aaattagaag atcaaaaagc ttcttttgaa cgttatataa ctgaatttga
     5701 aggctttaca gaccaatatc ctgaggaagt tgttgtagca ggtatattat ctatttctta
     5761 tggaaatgtt atggaaatgc tttatgctgg gatgaatgat gattttaaga agttttatcc
     5821 tcagtatctg ctgtatccta aagtttttca ggatgcttat caagatggta ttatttgggc
     5881 taacatggga ggagtagaag gctcgcttga tgatggactt accaaattta aggccaactt
     5941 tgctccgaca atagaagaat ttataggaga atttaatctc cctgtcagcc cactttatca
     6001 tattgctaat accatgtaca aaatacgaaa acagttaaag aataaacatt aaaagactcg
     6061 ccaaaatgag cgagtctttt aatgtttatt ctgttattcc cattcaactg ttgcgggtgg
     6121 tttacttgtg atgtcgtaga cgatacggtt aacgtggtca acttcattta cgatacgtgt
     6181 tgagattttt ttcaagacat cccaaggaag ttgagcaaag tcagctgtca taccatcaat
     6241 agacgtaata gcacgaatgg cgatggtata atcataagta cgaccatctc ccatgacgcc
     6301 tacagaacgg acacctgtgt taactgtaaa gtattgccac acgtcacgat caagtccagc
     6361 cttagcaatt tcttcacgaa ggatagcgtc tgattcgcga acggtttcaa gtttttcttc
     6421 agtaattgct cccatgacac ggatagcaag tccaggacct ggaaatggtt ggcgccaaac
     6481 aatttcttca ggcattccaa gagcgattcc aagcgctcga acttcatctt tgaaaagagt
     6541 gtttaagggc tcaatcaatt caaactgcat gtcttcgggg agaccaccca cattgtgatg
     6601 tgatttgatg gtttgagcag tttctgttcc tgactcaatg atatcagtat aaagtgttcc
     6661 ttgggcaagg aagtcaacac cttttaattt gctggcttca tcatcaaaaa catagacaaa
     6721 ttcattacca ataattttac gttttttctc aggatcttca acgtctgcaa gaaggtctaa
     6781 gaaacgtttt gaagcatcca cacggataat atttaggcca aatttgcccc caagcattcc
     6841 cataacttga tcgccctcgt ctttacgaag aagaccgtga tcaacgaaaa tacaagttaa
     6901 ttggtcaccg atagcttttt gaagtagaac accaacaact gaagaatcaa ctccaccaga
     6961 aagacctaga agaactttac gatcgcctac agtttcacga attttagcaa tttccatgtc
     7021 aataaaatta tccattgacc aatcaccacg cgcgccacaa attgatatag caaagttttt
     7081 aagaatgtca tttccataaa cagagtgtct cacttctggg tggaactgaa taccgtaaag
     7141 gtttttctca gtattttcaa tagctgcata gggacagtca tttgagtctc caacaaggtg
     7201 gaaaccttct ggaatttcag taacagcatc accatggctc atcaaaacga gttgttcttg
     7261 aggtgtgcct gaaaataatt ttgacgtttc acgaagatga agggttgact gaccgtattc
     7321 acgattacca gcttgtccag caggaacaac tttaccacct aatttatggg tgattaattg
     7381 cataccgtaa cagataccaa gaatcggaat ccctagttca aagatttcag ggtcaatgcc
     7441 aaaggcgtta tcagcgtaaa cagagttagg ccctcctgat aaaacgatac ctatgggatt
     7501 gatctcacga agttcttgag cggtgatttt atggcttttt agttcggaga aaacaccaaa
     7561 ctctcgaata cgtctagcaa taagctgatt gtactggcta ccataatcaa gaacgataat
     7621 tttttgaaca tcattcaaaa ttgaaatttc agtcattata atcctttcat tctataccaa
     7681 ccgtcaggct gatagttgtc aacttattgt agcatatttt catcgaaaag acattacaat
     7741 ttctctagct cgttggaaaa aaacgtaatc gttatgttac aatagaggct atgaaaggga
     7801 attaagacaa cagggagggc ctatgctaag aaaaaagaga attttgggtt tatttcgacc
     7861 tgttgaatta attttcctag gattattgtt gagtttagtt gtttcgtacc ttgcgtggac
     7921 caatagtttt gcaacacttc acaatatatt agcaactgtc ggaatagtgg aacgaagcaa
     7981 agatcaacag cctcgctatc acattggaca agctattcaa gtacaaaaaa gtggtccata
     8041 tcatcaatgg attggaacta ttaataaaca ggtagaagat atagccgaaa attaccgagt
     8101 gagttatcat tatgaagtgg tatttccaat aggaaaagtc actgtttctt tgccagaaca
     8161 taacctgaaa gagcctgata aaccgaggtt taaaaaagga gatatcgtta aattatcttc
     8221 attaactaaa aagccacata taaaagtgta tcaaggtcaa ttagcgacta ttaaacaagt
     8281 taaaaaacgc tatgactatt cgttaggagg atatcagtac gatattaacc tgaaagataa
     8341 tctaagatta gatggaattt cagagcaaga ttttgttaaa ccttattata ttaggttcaa
     8401 taaaggaaat tcccctgagc aaaacaatcg tcttttgcga aaagctttcg cttatgcaaa
     8461 gcagcatcca aatagcgtta tatcttttcc aaaggggcaa tttcacattg gctctttgcc
     8521 ttcacaaaaa gattattttg agcttccatc tgatacagct attattggtc atcagacaga
     8581 gttcattatt cacggtaaaa tgttgtggtt tggattccct acaggaccaa aggctgaaca
     8641 aggtgttcgt aatctcgtgt tgactggagt gcatttcaaa gcaaatgatt tgaaaaaagg
     8701 agaccacttt atgattatgg ctgatcatgg tactgattgg catatttacg ataacaaatt
     8761 tactatggtt cataagcgta atagtcatat ttttgattta ggatctctac aaaattcatt
     8821 gtttgagaaa aaccaattta ttggctatgc gccagaatta gtacaagacc aacagctgct
     8881 atcaaaggct caagggcatg attttttttc agaagtcatt cagtttgatg ctgctgttca
     8941 tcattttgca tgggatggag gtctacttag taatattgct ccaaactatg aagcatttaa
     9001 ccaaactcga catctatgtc acaatattac tgtaagccaa aatcaatttt taccttatat
     9061 agatccgact ggttgcctga gagcctatag tggttctatt ggtcagcatt cctcaaaagt
     9121 aggagttatt agggttttaa ataatgtttt tacctcatcc attgttacta aagcgaagct
     9181 cactagttgg tttatggaac ctattcattt tccaccaaat tcaccagtta ttgtcgcagg
     9241 taatatcatt aattgatgcc aaatacctca atatttacaa ttcaattttc atcaaaaata
     9301 tgataaaata gatgaataac cgacttgagg agtgtggcat gttaccagct tatataaaaa
     9361 ttcatgatgc aattaaaaaa gacattgatc tgggcatctg gccaattggt agtcgcttac
     9421 caagtgaacg acatttagcg gaacatttca ccgttagtcg aatgactcta cggcaggcta
     9481 ttacattact agtagaagaa gggattcttg aaaggcggat aggaagtggt acttatgttg
     9541 ccagtcatcg tgttcaagaa aaaatgcgag gaacaacaag tttcacagaa attatacgct
     9601 cccaaggacg acaaccctcc tctaaattat tatcctatca aaagcaatta gctagtgata
     9661 ccgaagttaa agaattgaac ttagacaaaa cagacttggt cattcgaatg gaacgtatcc
     9721 gctatgcaga cagtgtccct ttggtgtacg aaattgcttc aatcccagaa aaatttataa
     9781 aaacggttaa acgagctgat attacagaac acttttttca ctcattgata gcaaatggtt
     9841 acgagattgg taaaagtaaa cagacaatct acgctaagct agcaagtgag cgtgtagcct
     9901 cctacttgga agttgctaaa ggacatgcca ttttggctct aactcaggtg tcttacttta
     9961 cagacggcaa accttttgag tatgtccgca gtcagtatat cggtgaccgt tttgaatttt
    10021 acttagaaaa taattagtaa agaagtcatt tatgacttcc ttttttacac gaacagcata
    10081 aggcaattaa tttgctactg ttaaaaacaa tcatagtatg ataaaatgaa cattatggaa
    10141 attgaaaaaa caaacaggat gaatgccctt tttgaatttt atgcagcttt gctaacagat
    10201 aaacaaatga attatattga gctgtattat gccgatgatt atagcttagc tgagattgct
    10261 gatgaatttg gtgtcagtcg tcaggctgtc tatgataata ttaagcgtac ggaaaaaatt
    10321 ttagagactt atgagatgaa acttcatatg tattcggatt atgttgttcg aagtgaaatc
    10381 tttgacgaca tgattgctca ctaccctcat gatgagtatt tgcaagaaaa aatttccatt
    10441 ctaaccagta ttgacaatag agagtaagag gagttttgac tatggctttt gaaagcttaa
    10501 cccaacgttt gcaagatgtg tttaaacaca ttcgcggtaa aaagaaatta tcagaatcag
    10561 atgttcaaga agtgacaaaa gagattcgtc tagctctttt agaagccgat gtcgctttac
    10621 cagttgttaa aacctttatt aagcgcgtac gtgagcgcgc tattggccat gagattattg
    10681 atactcttga tccaacacaa caaattctta agattgttaa tgaagaatta acgagtattt
    10741 taggctcaga aaccgcggag attgataaat ctccaaaaat tccaactatt atcatgatgg
    10801 tcggtttgca aggggctggt aaaaccactt ttgcaggaaa actcgctaat aaattaatta
    10861 aagaagaaaa cgcgcgacca ctgatgattg ctgccgatat ttaccgtcca gcggccattg
    10921 atcagttaaa aacactgggg caacaaatca atgtacctgt ttttgatatg gggacagacc
    10981 actcagcagt cgatattgtc agaaaaggtt tggaacaagc tcgtgaaaac cgcaatgact
    11041 atgtcttgat tgatactgcg ggtcgcttgc aaattgatga aaaactgatg gaagagctgc
    11101 gcgatgtcaa ggctttagca caaccaaatg aaattctttt ggttgtagat agcatgattg
    11161 gtcaagaagc tgccaatgta gcctacgagt ttaatcatca gttgagcatc acaggagttg
    11221 tgttaacaaa gattgatggt gatacccgtg gaggtgcagc actatctgtc cgtgaaatca
    11281 ctggaaaacc aattaaattt acaggtattg gtgaaaaaat cacagatatt gaaacatttc
    11341 acccagaccg catgtccagt cggattttgg gaatgggtga cttactcact cttattgaaa
    11401 aagctagcca ggaatatgat gagaaaaaat ccttagagtt agctgaaaaa atgcgtgaga
    11461 acacctttga tttcaatgat ttcattgaac agttagatca agtgcaaaat atggggccta
    11521 tggaagacct cttgaaaatg attccaggaa tggctggtaa cccagctttg gccaatatca
    11581 aagttgacga aaaccaaatt gctcgcaaac gtgctattgt ctcttcgatg acccccgctg
    11641 aacgtgaaaa ccctgactta ctaaacccga gtcgtcgccg tcgtattgca gctggttccg
    11701 ggaacagctt tgtggaagtt aataaattta tcaaagactt taaccaagcc aaaagcatga
    11761 tgcaaggggt tatgtcgggc gatatgtcta agatgatgaa agatatgggc attaatccca
    11821 ataatcttcc taaaaacatg cctgctggta tgccagatat gtcttcctta gaagggatga
    11881 tgggacaagg tggtatgccc gatttatctg gccttggtgg tgatatggat atgagtcaag
    11941 tatttggtaa agggttcaag gggaaaattg gacaatttgc catgaaacag gccatgaaac
    12001 gtcaagctaa caaactaaaa aaagcaaaga aaaaacgaaa ataaaagaga cggaaatttt
    12061 cgtctctttt tgatgtgaaa ttcatttatc ttgtatacaa gattattaaa attatggaag
    12121 accgcgttac atgcatgatg agttcattta aaatttgaaa taacctaatc aatctaactt
    12181 aaatttctaa gggcctaaaa ttagcgataa ttttgccaat aatgcgaggt tcttcgctat
    12241 agggagcaaa cttatcagaa tattttttat ttaaggacac tagacgtaat ccctcatctt
    12301 cacgaaatac ctttttgata tatgtttgcc catcccattc gactgcataa attgctccat
    12361 cgtaatcaaa actattttgt tttataagaa caacttcgcc atttaaataa gttggctcca
    12421 tagaatctcc aaaaacccaa gacgcaaaat cgtattctaa ttgttcatcg taaaagacaa
    12481 catcaaagtt accatcacca aaataggagt aaccagtacc agcagataaa ctttcataga
    12541 cccgataagc atataattgt gatggtttat ctatgagatc tttagatttt ttgtctattt
    12601 gatgatttaa caatcgctct gaatagccaa ttactttttc tttattagat attgtcagct
    12661 ggttataagg cgttagcaat ctatagtttg ggtcgaaata atcagatgtc acattgaata
    12721 gatgcaataa ggcatttaaa tgtttttcat ttggtatatt cttacctttt tcccaattag
    12781 atattgtcat tttattgaca tgcaacaatc ttcccaattc tgattgagtt attccctttg
    12841 ataatcgtgc tgtttttagt tgatgtccag aaaacatttg gtagctcctt tagtaaagtt
    12901 ataactttac taatagtatc aaaaaaataa aacgaaagca agtgtaacat ttcctacaat
    12961 taattcatgt gatagcaata ctgtcaaaaa ggggaaacac ctaaaacata gcgactagat
    13021 tcgtgtacta gcaggtctat atctaataaa gagttaa
//
LOCUS       DATWVB010000044        12944 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.044, whole genome shotgun sequence.
ACCESSION   DATWVB010000044 DATWVB010000000
VERSION     DATWVB010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12944
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.044"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            597..1208
                     /gene="rpsD"
                     /locus_tag="VCX65_001469"
     CDS             597..1208
                     /gene="rpsD"
                     /locus_tag="VCX65_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEP5053924.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1365..2528)
                     /locus_tag="VCX65_001470"
     CDS             complement(1365..2528)
                     /locus_tag="VCX65_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP5053925.1"
                     /translation="MNIKEYKKKNGTIIYRTSVYLGVDQVTGKKARTTITASTKKGVK
                     IKARDALNNFAMNGYTVKEKPTVTTYKELTALWWESYKNTIKPNSRQSMEGIVRLHIL
                     PAFGDCKLSKLTTPVIQQQVNKWANNANKGIKGAYANYSFLNNINRRILQYGVTMQVI
                     EHNPARDVIIPRKQNNKEHKVKFFSNQELKQFLNYLDDLDLSSYENFFDYVLYKTLLA
                     TGCRIGEVLALEWSDIDLKKGTIKVSKTLNRYQETNTPKSKAGLRDIEIDRATVLLLK
                     QYKNRQQVLSWDLGRSETIVFTPFTTKYAYACLLRKRLQKHFKAAGVPDISFHGFRHT
                     HATIMLYAGIEAKDLQYRLGHSNISMTLNTYVHATKEGAKKAVSIFETAISNL"
     gene            complement(2708..3151)
                     /locus_tag="VCX65_001471"
     CDS             complement(2708..3151)
                     /locus_tag="VCX65_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5053926.1"
                     /translation="MENRLQKIRKEQTNLNQKDFFDQVVNKKLNLDISFRTYQNWENP
                     KNTIKPDKAQILADYFGVWLPYLLGNSNIRTEEQANFLAEMNKRINSEGDSFSFDMTA
                     TESDEHDLLYNYRQLETPYKNQVRKFTRDMWELQKESKNFSPKSP"
     gene            3320..3508
                     /locus_tag="VCX65_001472"
     CDS             3320..3508
                     /locus_tag="VCX65_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5053927.1"
                     /translation="MLITENIAVKVRKKRAVKQLGKVELSKKLGITPPTLSKIEAGNY
                     KAPKRIYASVMEWLAEDY"
     gene            3524..4090
                     /locus_tag="VCX65_001473"
     CDS             3524..4090
                     /locus_tag="VCX65_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HEP5053928.1"
                     /translation="MNRQVSIFEEVNDQGGAFQVVTTMTFHDRLLDIYGNIQEPLFRA
                     RDVAEMIDHSKTRNGYYDVQSMLRKVDDDEKVKGVPLEGATKNFRSGQKVWFLTEHGL
                     YEVLMRSSKPKAKEFRKAVKNILKEIRLNGYYMQGELVQNSQPTPDIDDLSYIKQKLT
                     DLQDVDSLQDLRWKMAKLYHVIETLDEY"
     gene            4147..4389
                     /locus_tag="VCX65_001474"
     CDS             4147..4389
                     /locus_tag="VCX65_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor protein"
                     /protein_id="HEP5053929.1"
                     /translation="MKATTYKELKKWIDEGVDLAELAQGYADKVPSVDREQFEAVTQG
                     IFNVLEGVSLMLDDKVLIYNRKAEQKRLNDIEQGDY"
     gene            4610..4792
                     /locus_tag="VCX65_001475"
     CDS             4610..4792
                     /locus_tag="VCX65_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053930.1"
                     /translation="MTSVRTAQLLNNGLGLVGQDLKDVLSALANSVNPSIEKQISHIM
                     IDRANTGEWLANVGKK"
     gene            4804..5136
                     /locus_tag="VCX65_001476"
     CDS             4804..5136
                     /locus_tag="VCX65_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053931.1"
                     /translation="MKYRVETNPFSKDRYTPEQLEMFKNRQLSKNKAEAYFTRLYNQH
                     IAWVIIANVMTEYVNKFRKSATSFEKAWDALGYQQTTEIVFRAVNGLPCSEKDTGELE
                     TYLSEVSA"
     gene            5136..5327
                     /locus_tag="VCX65_001477"
     CDS             5136..5327
                     /locus_tag="VCX65_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053932.1"
                     /translation="MQELNLTPTQTLILFIVLGLVGLLLSLSKPLIEIDLPEDTQVPK
                     PPQNANYGAYIQSQNHYYN"
     gene            5236..5604
                     /locus_tag="VCX65_001478"
     CDS             5236..5604
                     /locus_tag="VCX65_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053933.1"
                     /translation="MTYQKIPKYLNHLRTQTMGLIFNHRTIITIRREQMQLLSREAEL
                     ELLEKVGCYLEKRWQLELENKDDWDLIPRQDLLEKLDITGTTLKNWEKEGLKSYQSPF
                     ENSKKVYYRKSDIYNFLSVD"
     gene            5614..6135
                     /locus_tag="VCX65_001479"
     CDS             5614..6135
                     /locus_tag="VCX65_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053934.1"
                     /translation="MDYLEVTMTKDCVKIFNFLYKYPTKAYQKDEYFKLLYMHPLDSF
                     LTSFSLSGIRVKVTDKPVLAGWKLVRDIEVRIATGELLEMIEELEICYLRKHQTVSYV
                     EIKFYVVHLLTYGIRSRYDMQFFTKLLFCCGYDQETVIGIYSNITKNTRLSRDFITLQ
                     AKLYQTKKGTHEH"
     gene            6125..7738
                     /locus_tag="VCX65_001480"
     CDS             6125..7738
                     /locus_tag="VCX65_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage resistance protein"
                     /protein_id="HEP5053935.1"
                     /translation="MSIKENIDKLVSMEWTESIFGQSKMKADYKRQLSKVIELDTLSN
                     IHHNGETYAVSNQEVMYLSESKGRTHKFISGNVKTKSKGKGRDSQKYLVVSFDHQFPP
                     FAKLVVDYLLGRFTFFNNKLYDVNNRQAQVLDDFTIQSLYGFKKDNPFILEILEGIHQ
                     TLNIRPAKQLEAYKISGRDFIIDLKEHRLYRTNPSSDSSFFKFYDVDYHTAIGSKKKV
                     GKFLDYVIADHDSLHNATLQAYYIAQVACGLKSKQNFFISKSGVRTGKGLRHIGLSGI
                     FNKIDVELDLLIKGGFEASNAWGAFAGGEMALATEQGDIVGDKMERVLKIIATEKTHM
                     ARSIGGNLGTVNLTSVLCIDTNRTVALSDEMNGRAVLIQYQNRPEGETDLEREKAFEE
                     YWQTFTEMDKSPKIEGVIGFLLVSLDYFRKNDMKFDWRAVEVVNDDDLDDFQVYLINH
                     LSEKDFVERDSYVRELYNSTYGKNNNQAGQRMRTIGVKSYRKQTTGGRKIPGYKVDNI
                     KRFNKFSGGEKENTNIFDMFEKLNQPLPP"
     gene            8025..8198
                     /locus_tag="VCX65_001481"
     CDS             8025..8198
                     /locus_tag="VCX65_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2758 domain-containing protein"
                     /protein_id="HEP5053936.1"
                     /translation="MKIKLFYQKHNESLDDFEYRVNQFTLSVSVIDIKLSEATYGNYE
                     DMSTTTSLLVLYR"
     gene            8204..8377
                     /locus_tag="VCX65_001482"
     CDS             8204..8377
                     /locus_tag="VCX65_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001873750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053937.1"
                     /translation="MKLKLHTRGGNTITIQGDSAFYDELVKYLLSGRQPNWVTCPSAV
                     INLSDIIAITKEK"
     gene            8379..8705
                     /locus_tag="VCX65_001483"
                     /pseudo
     CDS             8379..8705
                     /locus_tag="VCX65_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258765.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8701..8946
                     /locus_tag="VCX65_001484"
     CDS             8701..8946
                     /locus_tag="VCX65_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053938.1"
                     /translation="MSNQMAVFNQFWAYQTLFQPTAQDIKLAILGYFTGTLWACEVSV
                     LEDVELGYRVIVSYVSCFDKSDRLLKIAQAVENSQLG"
     gene            8960..9118
                     /locus_tag="VCX65_001485"
     CDS             8960..9118
                     /locus_tag="VCX65_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053939.1"
                     /translation="MQTEVKDGFIYFKENGRIGVVEIPTFGKLTLSSKEGYIHQVDHS
                     FSTKHNQK"
     gene            9209..9997
                     /locus_tag="VCX65_001486"
     CDS             9209..9997
                     /locus_tag="VCX65_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053940.1"
                     /translation="MYKQTNKTYADILEKVEAATAQWIIRKKASSLKDDVIITDEDIQ
                     AEKERIFIEKYGTALFDFKIDSYRKELDDLKIKAREQVNQFNDFVKELEQDDRYTERG
                     KVDLYRAERKKAEKTLKEIGEAQHKLNVDIQKIEVESAQNAWKKLESEMTPDSITPSE
                     YQYLEMMLSRNDSDEMRKKLAEKFHYHLMVLEYLNADRKFGEVIIKHPLEGVKNQSVN
                     YIKIGDVRLPEVYESTYIHELLKHYKNDIYFGESYANHEWDEEQ"
     gene            9994..10260
                     /locus_tag="VCX65_001487"
     CDS             9994..10260
                     /locus_tag="VCX65_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053941.1"
                     /translation="MMSLECLRIYLKKSQFTELEHLLFRIIVLGGYPDDMYFPSRVRT
                     IITSLVNNIRKNLDSEGYRSVEELEEAIEKAISEHDEITQKGGG"
     gene            10302..10640
                     /locus_tag="VCX65_001488"
     CDS             10302..10640
                     /locus_tag="VCX65_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEP5053942.1"
                     /translation="MVAMVTSKTITEAAERAGITRGTAHRYLKDITFKKACRRYRSEL
                     MQQTTSLLQSASIEAVEVLRNIMLDDSISPYARQQSAQTILSTAYKAHELDDIVEMVE
                     ELEARFEDEQ"
     gene            10630..10905
                     /locus_tag="VCX65_001489"
     CDS             10630..10905
                     /locus_tag="VCX65_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053943.1"
                     /translation="MNSNLKKRVDKLRRLHSLDNASGIVFVEYADGKYQIKKQDHVPK
                     FIETRLIAEFESEEEAENFLSTIPSGYIIFWDIFPEEVEHVKKNKYL"
     gene            10880..11125
                     /locus_tag="VCX65_001490"
     CDS             10880..11125
                     /locus_tag="VCX65_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5053944.1"
                     /translation="MLKKINTYRRLEIIKNKLDEASKDSIEDIMLDWFRALHYALKVD
                     DTIDLPTFLEFKDNKALRDKIMADLGDFDPFEDLNIE"
     gene            11406..11753
                     /locus_tag="VCX65_001491"
     CDS             11406..11753
                     /locus_tag="VCX65_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEP5053945.1"
                     /translation="MNAKEQLKELKPLFALMTLFEEQRDKDIKLMNAFRNPELLNGIE
                     KGTAKQLLYLAKERDKRLAMIATLQDERQIAVIKARYVDDLSWDEIPDKLGYSRNTVF
                     KLHREALEVLDEP"
     gene            11743..12114
                     /locus_tag="VCX65_001492"
     CDS             11743..12114
                     /locus_tag="VCX65_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEP5053946.1"
                     /translation="MNHKNAIRKLKEFHRWQRIANSLNLTYNECYQFDIEYYSFRRKH
                     LEISRKCALEELDAIKHAINQLSKIEYRKILIECYLIGEKKPQQDIIAELNRSKSWYY
                     ETKRRALLEFVEFYRDGVLKK"
     gene            12267..12494
                     /locus_tag="VCX65_001493"
     CDS             12267..12494
                     /locus_tag="VCX65_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEP5053947.1"
                     /translation="MAMVSLRLNSAEEELFRSYATHTGKTLSELFKTALAQQIEDQLD
                     YETGIQALKRFEENPITYSIDDLIEELENDL"
     gene            12484..12753
                     /locus_tag="VCX65_001494"
     CDS             12484..12753
                     /locus_tag="VCX65_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEP5053948.1"
                     /translation="MTYKLVVSDEVKKQLKKMDKHVGLMLAKDMKKRLDGLNNPRQFG
                     KALTGQYKGLWRYRVGNYRVICDIVDNEMIILALEVGHRKEIYKR"
BASE COUNT         4415 a         2139 c         2605 g         3785 t
ORIGIN      
        1 aaaaaagagg tcttcaccat ggttaagcaa atgatcttag tactaaggtt aaaagattat
       61 cgtgaaataa agttttgaca caagtgtaat taatagagga acttgaagta tccggtaaaa
      121 ctatcttgaa gtgaaaaaac gagtagacct cccctgataa atacaatata ctagccattt
      181 cagagcaatt aagagtttcc agtgaagtgc ttttgataga gagctaagaa aaaaacagtc
      241 aaggtttaag aactgcaaat tagcatttaa attatttttt gttaatgaca gttgtcttta
      301 ttaccataac tataacttct tataatatag ccttcttaat tcatcagtgg tggttcgtcc
      361 catatctgac cttaaaatat taaactgatc atcagatgat agatagactg actttacaaa
      421 acaactttct tatggtaaac tgttctttgt gcgaaataac agcagaaaaa tatgaagctc
      481 gtcaacaggt ggttatctat tcaagtaacc tttgctgttt aggcgaaaac cccctgcacg
      541 aatcaggatt ttttaaaccg ttatttcctc aaaaaattta gaggaggaca tgtaatatgt
      601 cacgttatac tggtccatca tggaaacaat cacgtcgcct tggtttatca cttacaggca
      661 caggtaaaga attggcacgt cgtaactacg ttcctggtca acacggtcca aacaaccgta
      721 gcaaactctc agaatatggt ttgcagttag ctgagaaaca aaaacttcgt ttctcatacg
      781 gtttaggtga aaaacaattc cgtaacttgt tcgttcaagc tacaaaaatc aaagaaggaa
      841 ctcttggttt caactttatg gttcttttag aacgtcgtct tgacaacgtt gtttaccgtc
      901 taggtttagc aactactcgt cgtcaagcac gtcaattcgt taaccacggt cacatccttg
      961 ttgacggtaa acgcgttgat atcccttcat accgtgttga tccaggtcaa gtgatttcag
     1021 ttcgcgaaaa atcaatgaaa gtacctgcaa tccttgaagc tgttgaagct actcttggac
     1081 gtccagcttt cgtatcattt gatgctgaaa aacttgaagg ttcattgact cgccttccag
     1141 aacgcgatga aattaaccca gaaatcaatg aagcacttgt cgttgaattc tataacaaaa
     1201 tgttgtaata ttttattgaa taggataggc ttaaaagcct tgatactaag cactttgggg
     1261 cattattcca aggtgctttt tttgatttta ctaccctttt agttctcttt agtcggattt
     1321 tagtatagta agagggtagc cccaaagtgg ggcacccttg ttaattataa attgctaata
     1381 gctgtctcaa aaatcgagac ggctttttta gcgccttctt ttgttgcatg gacataagta
     1441 ttcaatgtca ttgagatatt agagtgtcct agtctatatt gcaagtcttt agcctctatc
     1501 ccagcgtaaa gcataattgt agcgtgggtg tggcggaagc cgtggaaact aatatcaggc
     1561 acgccagcag ctttaaaatg cttttgaagc ctttttctaa gcaaacaagc gtaggcgtat
     1621 tttgtggtaa acggagtaaa aacaatcgtc tcagaccgtc ctagatccca agataaaact
     1681 tgctgacggt ttttatattg cttaagaagt aagacggtag ctctatcaat ctcaatgtct
     1741 cttaatcctg cttttgattt aggagtgttt gtctcctgat atctattcaa agttttggaa
     1801 accttgatag ttcctttttt tagatcaata tcagaccatt caagagctag aacttctcca
     1861 atccgacaac cagtagcaag caaggtctta taaagaacgt aatcaaagaa gttttcatag
     1921 ctagataaat ctaagtcatc taaatagttc aagaattgct ttagttcttg attgctgaag
     1981 aactttacct tatgttcttt gttattttgt tttcgaggaa tgatgacgtc acgagctgga
     2041 ttatgttcaa taacttgcat agtaacgcca tattgtagaa tacggcgatt gatattattt
     2101 agaaaactgt agttagcata tgcgccttta atgcccttat tagcgttgtt agcccacttg
     2161 ttaacttgtt gctgaataac aggggtagtt agcttagata gcttgcaatc cccaaatgcg
     2221 ggcaaaatat gaagtcttac aatcccttcc atagattgcc gagagtttgg tttgatcgta
     2281 ttcttgtaac tctcccacca aagggctgtt agctctttat aagtggttac tgtcggcttc
     2341 tctttgacgg tatagccatt catagcaaag ttatttagag catcacgagc ttttatttta
     2401 accccttttt tagttgaagc tgtaatagtt gtgcgagcct tcttacctgt tacctggtcg
     2461 acaccaagat agacactagt gcggtaaatg attgtaccgt tcttcttttt gtattctttt
     2521 atgttcatga taataccttt ctaacatcag taagcaagta tgggatttag ttaggtattt
     2581 aggttttatc atgggtgata gttggttatc tggtagggtg gcgataaggt agagggtgtg
     2641 ttaatgctat ggttgtcaat ataagtgttg attattgttt ggtgggatag ttgcgagctg
     2701 gtcggtatca gggagatttt ggagagaagt ttttgctttc tttttgcaac tcccacatgt
     2761 ctctagtaaa ttttctaact tgatttttat agggagtttc aagctgtctg taattatata
     2821 ataggtcgtg ttcatcagat tcggttgcgg tcatgtcgaa ggaaaatgaa tcaccttcag
     2881 agttaattcg cttgttcatt tctgctaaaa aattcgcttg ctcttctgtt cggatattgc
     2941 tatttcctag aagataaggg agccatactc caaaatagtc cgccagtatt tgagctttat
     3001 caggcttgat tgtattcttt gggttttccc aattttgata tgttctaaat gaaatgtcta
     3061 gatttaattt cttatttacg acttgatcaa aaaaatcttt ttgattgaga tttgtttgtt
     3121 cttttcttat tttttgtagc ctattttcca aaagtattct cctttatttt aaaaacatta
     3181 taccattatc cattaaaaca aaaaagcata agacgaaaaa aaattggatt tttatcttga
     3241 caaccaaatt tatttgcgtt aatatagatt ttgcaaaaat aagacgaaaa aaaattgggt
     3301 ttttgcaaag gaggaatata tgcttattac agaaaatata gctgttaagg ttcgtaaaaa
     3361 aagagctgtt aaacagttag gaaaagtgga gctttctaaa aaattaggga taacgccacc
     3421 cactctatca aaaattgaag ctggcaacta caaagcacct aagcgtatct acgctagtgt
     3481 catggaatgg ctagcagagg attattagaa aggcaggaac aaaatgaata gacaggtcag
     3541 tatttttgaa gaagtcaatg atcaaggggg agctttccaa gttgtaacca ctatgacttt
     3601 tcacgatcgg ctattagata tttacggtaa tattcaagaa ccgttattta gagctagaga
     3661 tgttgcggaa atgattgatc acagcaaaac aaggaacgga tattatgacg ttcaatctat
     3721 gctaagaaag gtagatgatg acgaaaaagt taaaggcgtc cctttagagg gtgctacgaa
     3781 aaatttccgt agcggtcaaa aagtttggtt tttaactgag catggacttt atgaagtgct
     3841 tatgcggtca agcaaaccaa aagccaaaga gtttagaaaa gcagtcaaaa acattctcaa
     3901 agaaatccgt ttgaatggct actacatgca aggagagctt gtccaaaaca gtcaaccgac
     3961 cccagacatt gatgatttaa gctatatcaa gcagaagtta actgacttac aggacgttga
     4021 cagcttacaa gatttacggt ggaagatggc taagttatat cacgtcatcg aaacactgga
     4081 tgaatattaa gaaataagac aacaaaaaaa agcgcaataa tacgcacgga taaaggagaa
     4141 atgattatga aagcaacaac ttacaaagag ttgaagaaat ggattgatga aggtgttgat
     4201 ttagctgagc tagcacaggg ttacgctgac aaagtaccta gtgtagaccg tgaacagttt
     4261 gaagcagtca cacagggaat tttcaacgta ttggaaggcg tatcgctcat gcttgatgac
     4321 aaagtgctaa tctataatcg caaagcagag caaaagcgtt tgaatgacat tgaacaaggt
     4381 gattattaat taataatcaa gagtaacaaa aaaagccttg aactttggcg aggaacaggc
     4441 ttttcacttc aattaactaa aaccataaaa aagcaagtat gggatttagt taggtattta
     4501 tttaattata ccacaatcaa catcagggag ctacccctta aaactagcat gaatctagta
     4561 taagaaacaa gcaactacac agaaaataag aattaataag gaagataaaa tgacatcagt
     4621 tagaaccgca caattactta acaatggttt aggattggtt ggtcaagacc taaaagacgt
     4681 cttatcagct ctagccaata gcgtcaatcc aagtattgaa aaacagattt ctcacatcat
     4741 gatagataga gctaatactg gcgaatggtt ggcaaatgta ggcaaaaaat gaggtaagac
     4801 ataatgaaat atagagtaga aacaaatcct ttttcaaaag atagatacac tcctgaacag
     4861 ctagaaatgt tcaaaaatcg acaactcagc aaaaataaag cagaagccta tttcactcga
     4921 ctatataacc aacatattgc ttgggtgatt attgctaacg ttatgacaga atacgtcaat
     4981 aaattcagaa aaagtgccac cagctttgaa aaagcatggg acgctttagg ctatcaacaa
     5041 accacagaga ttgtctttag agccgttaac ggtttacctt gttcagagaa agacacaggg
     5101 gaactagaaa cttatttaag tgaggtatcg gcatgatgca agaacttaac ctcacaccaa
     5161 cacagacact tattttattc attgttttag ggcttgttgg gcttcttctt agcctttcta
     5221 agccattaat agagattgac ttaccagaag atacccaagt acctaaacca cctcagaacg
     5281 caaactatgg ggcttatatt caatcacaga accattatta caattaggag ggaacagatg
     5341 caattattat cacgagaagc agaattagag ctactagaga aggtgggctg ttaccttgaa
     5401 aaacgttggc aacttgaact agaaaacaaa gatgattggg atttaattcc aaggcaagat
     5461 ctactggaaa aactagacat tactggtacc acgttaaaaa attgggaaaa agagggctta
     5521 aagtcgtatc agtcgccatt cgagaacagt aagaaggtgt attaccgtaa aagtgatatt
     5581 tataattttt tgagcgttga ctaggaggac tttgtggatt atttagaggt caccatgaca
     5641 aaagattgcg taaaaatatt caattttttg tataaatatc ctaccaaagc ataccaaaag
     5701 gacgagtatt tcaaattact gtatatgcat cccttggaca gctttttaac aagtttctcc
     5761 ctatcgggca tccgagtgaa agttacagac aaacctgttt tagcagggtg gaaacttgtt
     5821 agggatatag aggttagaat tgctacgggg gaactcttgg aaatgattga agagctagaa
     5881 atatgctatt taaggaagca ccagacggtt tcttacgttg aaattaagtt ctatgtcgtc
     5941 catctattga cttatggtat taggtcacgt tacgatatgc aattttttac caagttgttg
     6001 ttttgttgtg gttatgatca agaaactgtt atcggtattt atagcaatat aaccaaaaat
     6061 accagacttt caagggattt tataacttta caggctaaac tttaccaaac aaagaaagga
     6121 acccatgagc attaaagaaa acattgacaa attagtatct atggaatgga ctgaatcaat
     6181 ttttgggcaa tctaaaatga aagcagacta taaacgccaa ctatctaagg tgattgagtt
     6241 ggatacctta agcaatatac accataatgg ggaaacctat gctgtttcaa atcaagaagt
     6301 catgtactta agtgagagta aaggtagaac tcataagttt atttcaggaa acgttaaaac
     6361 aaaatctaaa ggaaagggaa gagatagcca aaagtatctc gtggtttcct ttgaccatca
     6421 attcccacct tttgctaagt tagtggttga ttatctactt ggacgattta ctttttttaa
     6481 taacaaatta tatgatgtta acaatcgtca agcgcaagtg ttagatgatt tcactattca
     6541 atcgttatac ggcttcaaaa aggataaccc gttcatttta gagattctgg aaggaatcca
     6601 ccaaaccttg aatattagac ctgcgaaaca acttgaagct tataagattt ctgggagaga
     6661 tttcattatt gatcttaagg aacatcggtt ataccgaaca aatcccagtt ccgatagttc
     6721 tttctttaag ttttatgatg tcgattatca cacagcgatc ggtagtaaga aaaaagttgg
     6781 caagttttta gattatgtta tcgcagacca tgatagcttg cacaatgcaa cgttacaagc
     6841 ctattatatc gcacaggtcg cttgtggact gaaatcgaaa caaaatttct ttatctctaa
     6901 atctggtgtg agaactggta aaggcttaag acatattggg cttagcggta tctttaataa
     6961 aatcgatgtt gagttagact tattgattaa aggtggcttt gaagctagca atgcttgggg
     7021 tgcttttgct ggtggagaaa tggctctagc aacagaacaa ggggatattg taggcgataa
     7081 aatggagcgt gtgcttaaaa ttattgctac tgagaagacc catatggcta gaagtatcgg
     7141 tggcaattta ggaacagtta atttaacaag tgttctgtgt attgacacaa accgcactgt
     7201 tgcgctgtcg gatgaaatga atggtagggc ggttttgatc caataccaga atagaccaga
     7261 aggggaaact gatttagaac gtgaaaaggc ctttgaagaa tattggcaaa ccttcactga
     7321 aatggataaa agccctaaaa ttgaaggagt gataggtttt ttacttgtat cacttgatta
     7381 cttccgaaaa aatgacatga aatttgattg gagagcggtc gaagtggtga acgatgatga
     7441 tttagatgat tttcaagttt acctgattaa ccatctttct gaaaaagact ttgtagagcg
     7501 tgactcttat gttagagagc tgtataactc tacttacggg aaaaataaca accaagccgg
     7561 ccaaagaatg cggacgatag gggttaagag ttatcgcaag caaacaactg gaggacgcaa
     7621 aatacccggc tataaagtcg ataatataaa acgatttaac aaattctcag gaggagaaaa
     7681 agaaaatact aatatctttg atatgtttga aaagctaaac caaccactac cgccatgacc
     7741 cagacagtag gggttgtggg gggtataaac ccagtggtat caagggatag agtacaatca
     7801 cccataacca cctataacta tataggggag agagaattat ttttttagta gatatgttat
     7861 ttctttacat tatttttatt ttttctccct tatctatata gaaaagtggc ggtaggtggt
     7921 ggttgtgctg gcaaatggct caaccatgcg gttttaagca caccaccact ttatttaggg
     7981 ttgtgtctac acccaccact ttgagccaaa acaggagaaa aaacatgaaa atcaaactat
     8041 tttatcaaaa acacaatgaa tctttagatg attttgaata tcgggtcaat caatttaccc
     8101 tatcagtatc tgtaatagat atcaaacttt cagaagcaac ttatggcaat tatgaagaca
     8161 tgagtaccac aacttcttta ctggtcttgt acaggtaact gatatgaaac taaaattaca
     8221 cacacgaggc ggcaacacca tcaccataca aggagacagt gccttttatg atgagttggt
     8281 caaatacctt ctttctggcc gacaaccaaa ctgggtaaca tgtccttctg ccgtcatcaa
     8341 tttatcagac attatagcaa tcacaaagga gaaataatat gagaacattt tcagacacac
     8401 caaaaacatt cacatttcac tacacgttta aagactttga caccgcacaa gtagcctgtc
     8461 acgccattct aggctatatg actggtactt atgagcaacc agtgattgat gccacctatc
     8521 acaatgataa tcaaggcggg catgctaatc agttagtatt agaatatgcc gaggacagaa
     8581 agttaagcaa ggtcttcaag cgtatctgtg acagcttcaa ggattattac aaccaacctg
     8641 aggatatgac ggatgaagaa cttgatgaca tggttcaaga aaatgaatta atcaaggaag
     8701 ttgagcaacc agatggcagt atttaatcaa ttttgggcgt atcagacact ttttcaacca
     8761 acggcacaag atattaagtt agctatttta ggatacttca caggcacgct atgggcttgt
     8821 gaggtgtccg tgttggaaga tgttgaactt ggctaccgtg ttatcgtctc ttacgttagt
     8881 tgttttgata aaagcgatag actgctgaaa attgctcaag cagttgagaa tagtcagtta
     8941 ggatgaaagg aggtatttaa tgcagacaga agtgaaagat ggctttattt atttcaaaga
     9001 aaatggtaga ataggagtag tagagatacc tacttttggt aagctaaccc tatctagcaa
     9061 ggaaggctat attcatcaag tagaccacag cttttctact aaacacaatc aaaaataatt
     9121 atactgaccg aagaacggag gtatattcat gaagcttaat ggcttttttg gatatacctc
     9181 tttttgcatt taagaaagga aagacacgat gtacaaacaa actaacaaaa cttacgccga
     9241 tattttggaa aaagttgaag ccgcaacagc gcaatggatt attagaaaaa aagcttcaag
     9301 ccttaaagat gacgtgatta tcactgatga ggatatacaa gctgagaaag agcgtatttt
     9361 cattgagaaa tatgggacag cactgtttga ttttaaaatt gatagctacc gtaaagaatt
     9421 agatgattta aaaatcaaag ctcgtgagca agtaaaccaa ttcaatgatt ttgtaaagga
     9481 actagaacaa gacgaccgtt acacagaacg tggtaaagtg gatttatacc gagcagagcg
     9541 aaaaaaagct gaaaagaccc ttaaagagat tggagaagct cagcataaac ttaatgttga
     9601 tattcaaaag attgaagtag aatcggctca aaatgcttgg aaaaagttag aatctgaaat
     9661 gacgcccgat tcaatcaccc ctagtgaata tcagtattta gaaatgatgt tatcacgtaa
     9721 tgatagtgat gaaatgcgga aaaaacttgc tgagaagttc cattaccatc tgatggtctt
     9781 ggagtatttg aatgctgacc gtaaatttgg agaagttatc atcaagcacc cattagaagg
     9841 ggttaaaaat cagtcagtta attatattaa aattggggat gtccgattgc ctgaggttta
     9901 cgaaagcact tatattcatg aacttttgaa gcattacaag aatgacattt actttggcga
     9961 gagctacgca aatcatgaat gggatgaaga gcaatgatgt cattggaatg tttaagaata
    10021 taccttaaga aaagccagtt tacagagctt gaacacttgc tattcagaat tatagtgtta
    10081 ggggggtatc ctgatgacat gtatttcccc tcaagggttc gtacgatcat cacaagcttg
    10141 gttaataata tacgtaagaa tttagattct gagggttacc gtagtgtcga agaattggaa
    10201 gaagctatag aaaaggctat ttcagagcat gacgaaatca cacaaaaagg aggggggtga
    10261 tttttataga acatggttta acacctaaac aagagaaatt catggtagca atggtgacca
    10321 gtaaaactat caccgaggca gccgaaagag caggtatcac aagaggaact gcccatagat
    10381 accttaaaga cattactttc aaaaaggctt gtcgccgtta tcgtagtgag ttaatgcagc
    10441 aaaccacatc cttattacag agtgccagca ttgaagccgt tgaggtgcta cgtaacatta
    10501 tgttggatga ttctattagt ccatatgcaa ggcaacaatc agcccaaact atcttaagca
    10561 ctgcttataa agcgcatgaa ctagatgata ttgttgaaat ggttgaggaa ctagaagcga
    10621 gatttgaaga tgaacagtaa cttaaaaaag cgagttgata agttaaggcg actacatagt
    10681 ttagataacg cttctggtat tgtctttgta gaatacgcag atggcaagta tcagattaaa
    10741 aaacaagatc atgtccctaa attcattgag actagactta tagcagaatt tgaaagcgaa
    10801 gaagaagcag aaaacttttt aagcactatt ccaagtggtt acatcatttt ttgggatatt
    10861 ttccccgaag aggttgaaca tgttaaaaaa aataaatact tatagaaggc tcgaaatcat
    10921 caagaataag ctcgatgaag cgagtaaaga tagtattgaa gatataatgc tggactggtt
    10981 tagggctttg cattatgctc ttaaagtaga tgatacaatt gatttaccaa cgttccttga
    11041 atttaaggac aacaaggcat tgagagataa aataatggca gaccttggag attttgaccc
    11101 atttgaagat ctaaatatag aatagttaaa tggtgacagc atcgccacaa ggtcgtcata
    11161 aggagatagt tttttgactg tctccctttt tcgtcatcta ttccccatca gactaaaata
    11221 aaacatggtt ttagcgcttc tgtctgctaa gttgatgatt ttatattata agctctgaaa
    11281 agcgcttaga aacgatttta gagccgttct tccgctatca agaatgacta aaacaaaaag
    11341 acgtccacac ggaacgcctt catgattata tctgttaaca caattatacc acactggggg
    11401 ctttcatgaa cgccaaagaa caacttaaag aattgaaacc actttttgct ttaatgacct
    11461 tatttgagga acaacgagac aaggacatca agctaatgaa tgcttttcgt aatcctgagt
    11521 tactaaatgg catcgaaaaa ggtacagcta aacaactttt atatttagct aaggaacgtg
    11581 ataagagact agccatgatt gccacattgc aagatgagag acagattgcc gttatcaaag
    11641 ctagatacgt ggatgactta tcatgggatg agatacctga taaactaggt tattcaagga
    11701 ataccgtttt taaattacat agagaagctt tagaggtatt agatgaacca taagaacgct
    11761 attcgtaaac taaaagagtt tcatagatgg caacgtatcg ctaatagcct taatttaacc
    11821 tataacgagt gttaccagtt tgatatagaa tattattcct ttagacgtaa acaccttgaa
    11881 ataagccgaa aatgcgccct agaggagcta gatgctatta agcatgccat taatcaacta
    11941 tctaagatag agtatagaaa gatactgatt gagtgttact tgatcggtga gaaaaaacct
    12001 caacaagaca tcatagcaga acttaacaga agtaaaagct ggtattatga gactaagaga
    12061 cgtgctttac ttgaatttgt ggaattttac agagacggtg tgctaaaaaa ataatgttcg
    12121 tttatgataa cagagcaata gatataaatg ttaataatac agtgttagaa gagcttaaca
    12181 aggtatatca atacgggtaa ataattgact gattcctcct tatgttatac aatgtattac
    12241 agataaacaa acagaggtgg aagaatatgg caatggtatc attaagactg aacagcgcag
    12301 aggaagaact tttcagaagc tacgctacac acacaggcaa aacattatct gaattattca
    12361 agacagcact agcacaacaa attgaagatc aattggacta tgaaacaggt attcaagctt
    12421 taaaacgctt tgaagaaaat cccataactt attctatcga tgatttaatt gaggagttgg
    12481 aaaatgactt ataagctagt ggtgagtgat gaagtcaaga agcaactcaa aaagatggat
    12541 aaacatgtag ggcttatgtt agccaaagac atgaagaaac gacttgacgg gttaaataat
    12601 cctagacaat ttggaaaagc cctcacaggt caatataaag gactttggcg ctatcgtgtt
    12661 ggtaattatc gggtgatttg tgacattgtg gataatgaaa tgattatcct tgctttggaa
    12721 gttggacaca ggaaagagat atacaagcgc tagcaaatac aagacatggt acgaggtata
    12781 ataaaaagcg cagctaatga ccacgctatt tcttgcttac tgaactcatt attttaattc
    12841 ctttttagtt accctttaga tttctgatag tgtatctagt ttacactgtt tttagagaaa
    12901 taagagtgat aactcacttg gtttacagct actttacact acta
//
LOCUS       DATWVB010000045        11343 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.045, whole genome shotgun sequence.
ACCESSION   DATWVB010000045 DATWVB010000000
VERSION     DATWVB010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11343
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.045"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(9..281)
                     /locus_tag="VCX65_001495"
     CDS             complement(9..281)
                     /locus_tag="VCX65_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEP5053949.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            complement(298..1665)
                     /gene="dnaB"
                     /locus_tag="VCX65_001496"
     CDS             complement(298..1665)
                     /gene="dnaB"
                     /locus_tag="VCX65_001496"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEP5053950.1"
                     /translation="MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDD
                     FYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSA
                     NAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSG
                     FRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGK
                     TAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWN
                     NVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKP
                     ENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDA
                     DIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIA
                     QFEER"
     gene            complement(1695..2147)
                     /gene="rplI"
                     /locus_tag="VCX65_001497"
     CDS             complement(1695..2147)
                     /gene="rplI"
                     /locus_tag="VCX65_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEP5053951.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLTITEA"
     gene            complement(2144..4120)
                     /locus_tag="VCX65_001498"
     CDS             complement(2144..4120)
                     /locus_tag="VCX65_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEP5053952.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYHLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKHLLLKTINMTMKETGEVES"
     gene            complement(4210..6108)
                     /gene="mnmG"
                     /locus_tag="VCX65_001499"
     CDS             complement(4210..6108)
                     /gene="mnmG"
                     /locus_tag="VCX65_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEP5053953.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDAEYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            complement(6232..6549)
                     /locus_tag="VCX65_001500"
     CDS             complement(6232..6549)
                     /locus_tag="VCX65_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEP5053954.1"
                     /translation="MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRTKVNQLAFVVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSIN
                     WIK"
     gene            complement(7325..8446)
                     /gene="mnmA"
                     /locus_tag="VCX65_001501"
     CDS             complement(7325..8446)
                     /gene="mnmA"
                     /locus_tag="VCX65_001501"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEP5053955.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALISNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVAVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
     gene            8744..9415
                     /gene="sdaAB"
                     /locus_tag="VCX65_001502"
     CDS             8744..9415
                     /gene="sdaAB"
                     /locus_tag="VCX65_001502"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEP5053956.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGISIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
     gene            9427..10299
                     /gene="sdaAA"
                     /locus_tag="VCX65_001503"
     CDS             9427..10299
                     /gene="sdaAA"
                     /locus_tag="VCX65_001503"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEP5053957.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDNYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKEQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIDSQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
     gene            complement(10713..11327)
                     /locus_tag="VCX65_001504"
     CDS             complement(10713..11327)
                     /locus_tag="VCX65_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HEP5053958.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEESKDKSKSIASEPIPTVENSVAPTVTEEAPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
BASE COUNT         3507 a         2300 c         1843 g         3693 t
ORIGIN      
        1 ggcaaaaatc aatctaaata acgaattaat gttttttctg tcaaaatatc tgaataggtg
       61 tatgattcga cataagaatt atcaattgct cctggagtat cagagctatc actatactca
      121 atgataaaga gcgaactgta aacctcaata agcctaccaa ttttattttt ttcccgtttc
      181 cgtccattct caagggttaa ttctactaac tgtccttcat gggctcttat gtcctcttta
      241 atttttttca tttttgcaac atctgtaaat gcatcgctca ttttttgtct ctctttctta
      301 tctttcttca aactgggcta tacttgagaa tttgttgtat tctttttgaa acatcagttt
      361 gactgttcca cgcgccccag ctctattttt ctcgaggata acttcaattg tgttatcttc
      421 aacagcttct tcagcatcat caccttcttt acggtaataa tcgtcccggt ataagaaggc
      481 tacaatatcg gcatcctgct caatagatcc tgattcacga atatctgata aaactggtcg
      541 tttatcttgc ctttgctcaa cgccacgaga aagctgactt agggcaataa ctggtacttt
      601 caattcttta gctaggattt taagctgtct tgaaatatct gaaacctctt gctgacgatt
      661 ttcgggttta gttcctgtaa tcaactgtaa gtagtcaatt acgataagac ctaaaccacc
      721 atccacttct tgagacaatt tccgtgatct tgcgcggatt tcagtaattt taatcccggg
      781 cgtatcgtca atataaatcg gtgcttctgc caaagctccc tgagcaattg ttacattatt
      841 ccaatcctga tctgtgagtt gccctgttct taaactgtgc gaatcaacca ttccttctgc
      901 tgcaagcata cgatctacta aactttcagc acccatttcc aaagaaaaaa tagcaacagt
      961 ctttttttgc ttagtcccca cattttgcgc aatattaaga acaaaggcag tcttccccac
     1021 tgctggccga gcagctaaaa taactaattg atctgggtgt aaacctgttg taatcttgtc
     1081 aaggtctcta aaaccagttg gtaaacctgt aacatttgaa gtctgcttag aacgtgcttc
     1141 taaagcctcg taattaactt ttagcacatc tgaaattttg cgaaacccac tacgattact
     1201 atgttcattg agttcaatta aagctctctc aactccagcg ataacctctt ctggttttaa
     1261 aatttcatca taagctaggt tgacagattc tgtcaaccta gcaataatat cacgcaacat
     1321 agctttctca gctacaattt tagcataata ttctgcatta gcactagttg ggacactatt
     1381 aactagttca acaatatagg ataagccacc aatactttgc agatcatctt gatcatctag
     1441 gattgttctt atagtggttg catcaatggc atcattacga tcgctgaggg taatcattgc
     1501 ccgaaagata attttatgag cgtacttata aaaatcgtct ggactgataa attctctcac
     1561 tgcaatcagc ttatcaggtg agataaagat tgacccaaga acagattgct ctgctagtaa
     1621 atcttggggt tgaactcgta attcagctac ttcaggcaac ctcataacct ccaaatcttg
     1681 tgatgttttt tatattatgc ttctgtgata gtcaatttaa tctcagctgt tacttcctta
     1741 tgtaatttca caggaacttc aattagacca atggcgcgga taggatgatc taaaacaata
     1801 tgacgtttat caacttttac accaaattgc ttttgcaatt cttctgaaat ctttttagct
     1861 gtgatggaac caaatgtacg tccatctgga ccaacttttt cttgaaattg aacacgtgtt
     1921 ttgtcctcat ccaaaacagc cttgacagct tgagcttctg ctaatatttc agcttgagct
     1981 ttttcttcag ctttttgttt tccttttaat tcaccgatgc tttgactagt tgcttcttta
     2041 gctaaatttt tcttaataag gaaattttga gcatagcctg ttgggacctc tttgatttct
     2101 ccttttttac cttttccttt tacatctgct aaaaaaataa ctttcatgat tctacttctc
     2161 ctgtttcttt cattgtcata ttaatagttt tcaataataa gtgcttcgct tggggaagac
     2221 tgatatccgt taactgacag gcagcaagat taaagtggcc tcctccacct aatttttcca
     2281 tcacacgttg aacattgatt ttactacgac ttctagctga aatagcaatc ttatgagaag
     2341 ctgtttcaac taatacaaag ctagcctcaa cgtgagccat tgacagtatc gtatctgcag
     2401 ctttactagc aataacattg ctataaagat gatttttttc tcctgcagct acaatgatac
     2461 tgtcaccaag acgttctcct tgtaaaataa tttcatttat ttgcttatat tcttcaaaat
     2521 ctgttgcgga tatattttga atttcaacac tatcacttcc tttgcttctt aggtaactag
     2581 cgacatcaaa ggtacgactt gtcactcgcg tagaaaaatt tttagtatca agcataatac
     2641 ctgccattaa aacactggct tggatcttat ttaaacgttt tttagcattt tgaaattgaa
     2701 ttaactcagt gacgagctcc gcagcactac ttgctccact ttcaataaaa gttaagatag
     2761 cattatcagg aaaatcatca tctcttctgt gatgatcaac tacaataaca ttttgaaact
     2821 gttcataaaa ttctttagaa agtgttaaag atatcttaga atggtcaacc attactaaaa
     2881 gtgatcttgg agtcactaaa cccattgctt gagaaacact gattagacga gtctttccgt
     2941 cagcctgcaa tcgctcaata gccctttcaa tatctggact catctcatct ggattgtaaa
     3001 cggcaaaact attttcaata atgttacctg cgaaaaattg cataccaaca gctgaaccta
     3061 gtgcatccat atcaagtttc ctatgtccaa caataaaaac attgtccacc atcttgattc
     3121 gatctgaaat agctgtcatc atagcacggg tacgtgttct tgaacgttta actgtagaaa
     3181 cagaccctcc cccgaaataa attggattcg tatgatccgc attttcacga atgacaatct
     3241 gatcaccacc acgaacaagc gcaatattaa gattctcaag agctacctgt ccaatctggc
     3301 tatgattttc ttcaccaaaa gaaattccta tgctgagtgt taaagggcgt tgagcatctt
     3361 gagcttcttt acgaaactct tctaagacag aaaatttatt atccatcaaa tcatttaatg
     3421 ttttaaagtc tgtaaagaaa tagtagcgat ccatattaac acgacggtaa aaaatccgtt
     3481 ttgactccat aaactcatca atgaagttag ctacaaatga attaattttt gaggtatctg
     3541 catctgataa atcatcagtg atatcatcat aattatcaac cgaaataatg ccaacaaccg
     3601 gtcttaacat actagcatca gctaattgcc tgtttcccac aaagctatca aaaaaataaa
     3661 aaattcctga tgatacatca atataagaag tgtatttatt accagaaact tcaaatgttt
     3721 gagaaatatc ttcacgacgt ttttccgtaa taatttgctg aatcaaactg ttttgtataa
     3781 aaccctcttc agttgtaaaa attaattctg cataaggatt ataccattct acagcgttgg
     3841 tctcttgatc aaattgaact actccaacag gcatattatc aagtagcgtt tttaggttat
     3901 cttctgtttg ttcatttaag agctcaatat gagctaagtc tgataagtga taagcttctt
     3961 tttgatacca taaaagagca acaacaaata gcaaaacgag aaaaatagct aataatatta
     4021 atatttttga ttgcataata ctgacacaaa gtgccagtag tccaaataaa atcaatccca
     4081 tcataatcaa atgaatggtt tcaaaacgaa attttttcat cttataacct cttaagcaca
     4141 cattatacca taaaaaagcc ctgaaataca gagcttccac ttgctttgag attacaattt
     4201 catttccatt taatattttc gatgagcttt tccgtttcct tctaaataaa tcatcaagat
     4261 actgatgtcc gcaggattga ctcctgaaat acgactagct tgtccaattg tttcaggatt
     4321 aattttctta aatttctgac gcgcctcagt tgcaatagaa tcaatagcat cccaatcaat
     4381 atttgcagga atacgttttt cttccatgcg tttcatctta gcaacctgat ctaaagcttt
     4441 gcgaatatag ccttcgtact tgatttctgt ttctaaaagt tcaatgattt tagcatctaa
     4501 atcttcagcc gcaggaccaa caaaagagac tgcagtcgca taatcaattt ctgggcgacg
     4561 cataaattct ttagctgtca tagcatccgt caatggttta aaaccaagtt cctgcacacg
     4621 atcgttggtt gcttttactg gttttaattt gatactgttc agacgtttta attcgttatc
     4681 aaattggttt ttcttaattt cgaaggcctt ccaacgctca tcatcaacca acccaatgtc
     4741 gcgaccaatc tctgtcaaac gcatatcagc gttgtcatga cgtaaaatca aacgatactc
     4801 agctcgcgat gtcaacaatc gataaggttc caaggttcct ttggtaacca aatcgtcaat
     4861 cataacgcca atataagcat cgctccgttt caaaataagt tctggcttac cttgaacttt
     4921 caaagcagca ttgattccag caataagtcc ttggccagca gcctcttcat acccagaagt
     4981 tccattagtt tgcccagccg taaagagtcc tgaaattagc ttggtttcaa gtgtggcacg
     5041 tagctggtga ggtaaaacaa tatcatattc aatagcataa ccagtgcgca tcatttcagc
     5101 cttttcaagt cctttgatcg aatgaatcaa atctttttgg acatcttctg gaagactcgt
     5161 tgacaaccct tgaacataca cttcttctgt atcacgcccc tctggctcta agaaaagttg
     5221 atgacgttct ttatcagcaa agcgaacaat cttatcttca atagatgggc agtaacgagg
     5281 gcctacacct ttaacaatgc cagaaaacat cggtgctctg taaaggttct gattaatgat
     5341 atcatgacta gtttgattcg tataagtcaa ccagcaggga atttgatctt tgagatactc
     5401 agcatctttt gacataaatg aaaaatgatt aggtttgtca tcacctggct gaatttccgt
     5461 ttgatcgtaa ttaatagaag atgctttgac acgaggaggc gttcctgttt tgaatctgcc
     5521 aatttctaag ccgagttttt ttaaattatc tgctaaagtt actgatgcca aactattatt
     5581 aggcccagaa gaatatttga gttctcctaa aataatttcg ccacgcagag ctgttcctgt
     5641 tgtcactaca actgccttag ctgcaaattt ttgtcctgtg gctgttaaca cacctacaac
     5701 tcgtccatct tcaactagaa tatcatcaat catcgtttgg cgaagagtca aattagcctg
     5761 tttttcaacc gtatgtttca tttcacgcgc atacagggat ttatctgctt gagctcggag
     5821 agcgcgtaca gctggtccct tacctgtatt aagcattttc atctggatat aggttttatc
     5881 aatattttta cccatttcgc cgccaagagc atcaatctct ctaaccacta tccctttggc
     5941 agatcctcca atagaaggat tacacggcat aaaagccaac atatcaaggt tgattgttgc
     6001 caataaagtt ttacaaccca tacgactagt ggccaaactg gcttcaacac cagcatgacc
     6061 tgcacctatg acaatgacgt catagctttc tgtaaattca tgtgtcattt ttttaaaatc
     6121 ctttatttca gtctattcat ttaaaatcat acgctttagt ttagccttca atgcggacaa
     6181 tatgtcctgg ccatttagcc aactcggttt gtaaaaactc aggaacaaga ttcatttgat
     6241 ccagttgatt gattggaatc cattcacaaa cctgtcgctt gcattctcta tcatttctag
     6301 tttagggtct tctaaggggc ttaccaaata atgaaattca atattatgcc agaaaacatc
     6361 atcgatatca aaatgattct caaccacaaa agccagttga ttaaccttag ttcgaatacc
     6421 aacttcctct aaggtttcac gtaaaacagt ttcatgcgtt ttttcaccta ccaaacttgt
     6481 accaccaatg gtgtaatatt ggtcagctgc atctctagtt aaaaaattct taccatttct
     6541 aacaatcaag cactagctcg taaactaaag ttatctgacc tctagtgatt ctaaatccca
     6601 gtcctattag ccatctcaat tctagagcta aaccataaaa agggccaaaa ccctagaaga
     6661 ttgcaggaca aaaaaaccta caactttcat gagctttgac catcattccg attgttatta
     6721 tctattttaa aaaaatgatt agtgattgtc aatattgatt tcatcacaga cctttacagt
     6781 aatgtcaatg tttttacatc tctgtcaatc tattgtaatg tttttaaaat gattacaaaa
     6841 gtatcactat gtctaatcta gcgaggcgag aaataaaaat gtcatcagta ttatcatacg
     6901 attttttgat atcttctaaa gtagtaaaat acagataccg ttgtttctaa gtctacaagt
     6961 aagaacgccg ataacaaaac cataaaagta taactagaaa tttccaataa ttttttacac
     7021 atttagtatt agataatagg tactaataat catgaaataa tctgttttac gaaataccta
     7081 atcatcaaaa tatctgttgt aatactagag aaagtgagtc tcatgatcgt atgatttcta
     7141 cagtaactaa taaagtaatg actcaacttt tacgaactat ttttaaaaat aatgtgatta
     7201 tatttaaaat atacagatat cataaattaa tccattaacg catgattggt ttttataaat
     7261 aatatcatat gatgtataag gaattgttga atgtcccttt ctttttatct taataaaaga
     7321 ttcattaaat gtactgacaa ggctgcccat ttttataagc catgtcaatc ataccaccac
     7381 caaggcattc ttttccgtca tagaaaacaa cagcttgacc aggagtaatc gcgcgctgtg
     7441 gctctgcaaa aacaacttct gccttatctc ctcgaacatg caccgccacg tgtgaatcgg
     7501 gttgacgata gcgaaattta gcagtacatt caaatgtgaa ctcttctggc atctcacgtg
     7561 taaaatggat gactgaggcg tcaagactat ttgatattag ggcttcatgg tagaaacctt
     7621 gaccaacgta taaaatattt tgcgacaaat ctttaccgac aacaaaccaa ggttgattat
     7681 ccccaccatg ctgaccacca atgcccagac caccacgctg accaatagta taatacataa
     7741 gaccggcatg ttctcccata tcgcgaccat caatagtcat catgcgacct ttttgtgccg
     7801 gtaagtactg gctcaaaaac tgtttgaaat tcttttcacc aataaaacaa atacctgttg
     7861 aatctttctt tttagccgtt gcaagtcctg ctcgctcagc gatttctcta acttctgact
     7921 tttgcaaatg accaaggggg aataaagtct tttgtagttg ttcctgtgat agttgactta
     7981 aaaagtaggt ttggtctttg ccattatcag ctccacgtaa catgtgaacc gtaccatttt
     8041 catcacgctt gacttgagca tagtgtcccg ttgctacata atctgcacct aaagtcatgg
     8101 catagtcaag gaaagcttta aattttattt ccttattaca catgacatcg ggatttggag
     8161 tacgacctgc tcggtattcg gccaagaaat attcaaatac tctgtcccaa tattcttttt
     8221 caaaattgac tgagtagtaa ggaataccga tttgatcagc aacggctgct acatctttgt
     8281 aatcttcagt agctgtgcaa acaccaaatt catctgtatc gtcccagttt ttcatgaaga
     8341 caccaataac atcataacct tgctccttta aaagtagagc tgttacagat gaatcaacgc
     8401 caccactcat accaacgaca acacgtatct ttgagttatc tgtcataaaa aattctccca
     8461 tcaataataa gatagaaaaa gataatcatc atattatgaa tattatgatt ctttttctta
     8521 tcagttaacg tacgattgaa ggtcgtcgtt ttcaaaagtc gatttgaagg tcgattttga
     8581 agcgccatca gcgcaaacct tattataaca attactgcgt ggaatgccaa tcattttatt
     8641 gctcaataat tttttattat aaaaataatt ttttataatt atattgctgt tttttgatat
     8701 ttttttgtta taataaacat agaaataaaa aacggagttg cctatgaata cacaaaaatt
     8761 tcaatcagtt tttgacatca ttgggccagt aatgattggt ccatcaagta gtcacacagc
     8821 tggtgccgtc agaattggta aggtagtcca ttccatcttt ggagatattc ctgatgaagt
     8881 gacgtttcac ctttataatt catttgctaa aacctacaga ggacatggta ctgataaggc
     8941 tcttgttgca ggaattatgg gtatggatac tgataatcct gatattaaaa attctctaga
     9001 aattgctcat caaaaaggga taaaaatcta ttgggatatc ttaaaagata gtaatgctcc
     9061 ccatcccaat actgttaaaa tcagtgtcaa aaaagctgac aaaacactta gtgttactgg
     9121 tatttcaatt ggaggaggaa acattcaagt aacagaacta aatggttttt ctgtctcgtt
     9181 atccatgaat acccctacta tagttactgt acacaaagat attcccggaa tgatcgcaaa
     9241 ggtaactgat atcctatctt ccaataatat taatatcgcc acaatgaatg ttacacgtga
     9301 atccgctggt gaaaaagcta ctatgattat agaagtcgat tctagagagt gccaagaagc
     9361 agccaaccaa attgcaaaaa ttcctcatat ttataatgtc aacttctttg actagaaagg
     9421 aaagctatgt tttatactat tgaagaactt gtcaaacaag ctgaccaaca atttaatgga
     9481 aatattgctg aactcatgat tgccacggaa gtggagatgt ctggaagaaa tcgagaagat
     9541 attatcaaaa tcatgtcacg caatttacaa gttatgaaag cagctgtaac agaaggacta
     9601 acctcaacca aatctatcag tggtttgaca gggggcgatg cggtcaaaat ggataactac
     9661 attaaaaaag ggaacagcct ttctgatact actattctta atgctgttag aaatgctata
     9721 gctgtaaacg aattaaatgc taaaatggga cttgtctgtg caacacccac tgcaggaagt
     9781 gcaggatgct taccagcagt gctcgcaaca gctattgaaa aacttgactt atcagaaaaa
     9841 gaacaattag agtttttatt tactgcagga gcttttggtc ttgttattgg aaataacgcc
     9901 tctatttctg gtgcagaagg tggatgccaa gcagaagttg gttctgcagc tgctatgagt
     9961 gcagctgctc ttgttaaagc agctggtgga acatctcatc aagctagtca agctattgcg
    10021 tttgttatca aaaatttatt aggacttgtc tgtgatcctg ttgccggcct agtagaagtg
    10081 ccttgtgtca aacgcaatgc tctaggagca agtttcgccc ttgtcgcagc tgatatggct
    10141 ttagctgata ttgattctca aattcctgtt gacgaagtta ttgatgctat gtatcaagtc
    10201 ggctctgcca tgccaactgc tttccgtgaa acagcagaag gtggtttagc cgctactcca
    10261 actggacgac gttacagcgt agaaatattt ggcgaataaa tagatagtta gaaaaattct
    10321 tagaaatatt tgaaagcgtt ttatttttct gctatatatt cactaaaatg actaatagat
    10381 agctatcaag ctatgttgtt tccccttaga aacaacttct agtaaattgt taaaactcaa
    10441 aagtgtagta gtgtaaaata ctgaaaattg ctaatgatct tataaacatt taagagtttt
    10501 tttcctgctt gttatcagta taactgcctt aaatatcaga ggcacttaag tgctggtcag
    10561 ttttcctaaa taatacgagc tatattccct gataaggcaa tgttttgttt tgagactaat
    10621 tcatcactac aaatcataaa gacaattaaa taccaaaaac ctattgttag taaatactaa
    10681 caataggttt tatttcttcc agctatgttt atttagtaac cccaagctga taaaccttgt
    10741 gcactatagg ctttcaaggc tgcattgact tgatcttcaa ccgttgctgt agaaccccaa
    10801 cctggcattg tctggaacaa ccctgatgcc ccagaagcat tagctgcgtt aggatttcca
    10861 ttagattcac gcgcaattat atgttcccaa gttgattgtg gaacacctgt tgctgctgcc
    10921 atctgtgccg ccgcttgact tcctacaata ccagcagtat ttccattgga aagtaccaca
    10981 ttgtttggat tataggctac tgaagatacc tgctgaacag tttgagtcac ttcttgctga
    11041 acaaccggtg cttcctctgt tactgtcgga gctacagagt tttctactgt gggaataggc
    11101 tccgaagcaa tgctctttga tttatctttg ctttcttctt tagtaatagc atgattattt
    11161 tttggagcct tgtcgattgt taccatttta ctttctgact tcttagcata agacttagta
    11221 tcagcatttt tacttgagaa ggcaaaaatg atggctaata ttgttagagc taacgctact
    11281 aatccaaaat taaaataacg ttgttttaaa ttttctttct taaacattca ataatacctc
    11341 act
//
LOCUS       DATWVB010000046        10749 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.046, whole genome shotgun sequence.
ACCESSION   DATWVB010000046 DATWVB010000000
VERSION     DATWVB010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10749
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.046"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            15..752
                     /locus_tag="VCX65_001505"
     CDS             15..752
                     /locus_tag="VCX65_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP5053959.1"
                     /translation="MGKEIKVKYFLRRSAFGLVAVSASVLVGSTVSAVDSPIEQPRII
                     PNGGTLTNLLGNAPEKLALRNEERAIDELKKQAIEDKEATTAIEAASSDALEALVDQA
                     DALQSEEAAVVQSDTAASDALEALADQTDALQSEEAAVVKADTAASDALEALADQTDA
                     VQSEEASVVKADTAASDAWEKAATPTALDVKKTKDTTPVVKKEERQNVNTLPTTGEES
                     NPFFTAAALAITVSTGALVVSSKCKEN"
     gene            990..1532
                     /locus_tag="VCX65_001506"
     CDS             990..1532
                     /locus_tag="VCX65_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP5053960.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            1541..2824
                     /locus_tag="VCX65_001507"
     CDS             1541..2824
                     /locus_tag="VCX65_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEP5053961.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCENSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            2840..3700
                     /locus_tag="VCX65_001508"
     CDS             2840..3700
                     /locus_tag="VCX65_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEP5053962.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTRSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            3702..4667
                     /locus_tag="VCX65_001509"
     CDS             3702..4667
                     /locus_tag="VCX65_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEP5053963.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            4778..6061
                     /gene="aroA"
                     /locus_tag="VCX65_001510"
     CDS             4778..6061
                     /gene="aroA"
                     /locus_tag="VCX65_001510"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEP5053964.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            6054..6545
                     /locus_tag="VCX65_001511"
     CDS             6054..6545
                     /locus_tag="VCX65_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEP5053965.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QYGEIAFRTIESQVLKDLLFANDNSIIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            6753..8204
                     /locus_tag="VCX65_001512"
     CDS             6753..8204
                     /locus_tag="VCX65_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEP5053966.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDTPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            8286..9920
                     /gene="rlmD"
                     /locus_tag="VCX65_001513"
     CDS             8286..9920
                     /gene="rlmD"
                     /locus_tag="VCX65_001513"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEP5053967.1"
                     /translation="MLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVDNALPEEVIDMR
                     VLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQLTFKKKQVQDS
                     LYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKHSHDLIPISDYY
                     IQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGEMMLVLVTTRPK
                     VFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTITDSMLGNNYAI
                     SAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFAKTVKAVYGVEV
                     IEAAVRDAQHNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVDPPRKGLTESFI
                     QASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQTHHVETVALLSK
                     LGVDKHINIEIEMDELDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKRKCGIEL
                     REHYNKSKKEKQIIPQCTPEKEEAIMDALRHFKMIE"
     gene            10076..10612
                     /locus_tag="VCX65_001514"
     CDS             10076..10612
                     /locus_tag="VCX65_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEP5053968.1"
                     /translation="MRSYESKEELKNEIKKTFEKYISEFDNIPEELKDKRLEEVDRTP
                     AENLAYQVGWTTLVLKWEEDEKKGIDVKTPSDKFKWNQLGELYQWFTDTYAHKSLYEL
                     KEQLTENVKKIYLMIDELTDEELFKPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKLVLYIEKYK"
     gene            10632..>10749
                     /locus_tag="VCX65_001515"
     CDS             10632..>10749
                     /locus_tag="VCX65_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyketide cyclase"
                     /protein_id="HEP5053969.1"
                     /translation="MAVAKIKVTLNCPIEKVWDKVTDLRDFSWRSDIKDIKII"
BASE COUNT         3623 a         1762 c         2206 g         3158 t
ORIGIN      
        1 aaaaaggaga aacaatggga aaagaaataa aagtgaaata ctttttgcgt agatcagctt
       61 ttggattagt tgcggtgtca gcatcagtat tagtcggttc aacagtatct gctgttgact
      121 cacctatcga acagcctcga attattccaa atggcggaac cttaactaat cttcttggca
      181 atgctccaga aaaactggca ttacgtaatg aagaaagagc cattgatgaa ttaaaaaaac
      241 aagctattga ggataaagaa gctacgacag ctatagaagc agcaagttca gatgccttag
      301 aagcattagt ggatcaagca gacgctttac aatcagaaga agctgcagta gttcaatcag
      361 ataccgctgc tagtgatgcc ttagaagcat tggcggatca aacagacgct ttacaatcag
      421 aagaagctgc ggttgttaaa gcggataccg ctgctagtga cgccttagaa gcattggcgg
      481 atcaaacaga cgctgtacaa tcagaagaag cttcagttgt taaagcagat accgctgcta
      541 gtgacgcctg ggaaaaagca gcaactccaa ccgctttaga tgttaagaaa actaaagata
      601 caacacctgt agttaaaaaa gaagaaagac aaaacgttaa tacccttcct acaactggtg
      661 aagagtctaa cccattcttt acagctgctg cgcttgcaat aacggtaagt acaggtgcgt
      721 tagttgtaag ttcaaagtgc aaagaaaatt agttgctatt tgttctagca aatgaaacaa
      781 gagaatcgaa agattctctt tttctgatat ttaaaaatgc tacagtttat aatagcttga
      841 aagactaaat gttctcaaac tcattagaac aagctttaat aaaactaacc cagttgtatc
      901 aaaggataga taaagactaa gactgttata gaatatttgc aaaagatttg ttataatgga
      961 cccaatacag gtattgtgaa aggtataata tggatatttg gacaaagctt gcagtgtttg
     1021 ctttttttga gactccgaaa gtaatattac ggccttttcg ctatgaagat cattgggatt
     1081 tttacagcat ggttaacgac actaaaaacc tttattatgt ttttccagaa caaaaaacta
     1141 aggcagcaag tgactatctt ttagtacata gttttataaa gtttccttta ggtcagtggg
     1201 caatagaaga taaagcaacc caccaagtaa taggttctat tagaattgag cattatgatg
     1261 ctaaaacgcg ttgtgctgat attggctatt ttttaaacta tgccttttgg ggacaaggaa
     1321 ttatgacaga agtcgtaata aaacttgttt atttatcttt tcacgaattt ggtctcaaaa
     1381 cgttgcgtat tataactcat ttagaaaata aggccagcca gaaagtagct aaaaaagcag
     1441 gttttcaact aaaaacctgt tttaaaggaa gtgatcgtaa tactcataaa atctgcattt
     1501 ataaaatgta ccaactaact aatgataggt gataatcatt atgagcaaac atcaagatat
     1561 tttagattat ttagaaaaac ttgctattgg taaaaaagtg agtgttagaa gcatttcaaa
     1621 ccacttaaaa gtaagcgatg gaacagccta ccgtgctatt aaagaggcag aaaatcgagg
     1681 tattgtcgaa accaaaccaa gaagtggaac tgttcgtatt gaaaaaaaag gacgggttcg
     1741 tattgaccgt ctgacctatt ccgaaattgc tcggatcagt gattcggaag tgctagcggg
     1801 acatgctggt ttaggacatg aattcagtag gttttcaatt ggtgctatga ctcaacaaaa
     1861 tattcgtcgt tacttggtca aaggagggtt attaatagtt ggggatcgtg aaacgattca
     1921 actcttagct cttgaaaacc ataatgccat tttggtgacg ggcggatttc cagtatccaa
     1981 acgtgttatt gaaatggcaa ataaccaacg aatcccagtt atggtaactc attatgatac
     2041 ctttactgtg gcaacaatga ttaatcacgc gctatctaat attcgtatta aaacagatct
     2101 caaaacagtt gaacaggtaa tgatacctat tacagattat ggttaccttt gcgaaaacag
     2161 ctctgttgaa gaattcaata cattaataaa aaaaacacga caagtcaggt ttcctgtatt
     2221 agattataaa agaaaagtga ttggtgtagt tagtatgcgt gatgtggtgg atcagttgcc
     2281 aacaactaag cttaccaagg tcatgtctaa aaatccaata acggctagac caaatactag
     2341 tcttgctaat attagccaga aaatgatctt tgaagattta aacatgttac ctgtcactga
     2401 cgaagaaaac aatttacttg gtatgattac tcgtagacaa gcaatggaaa atttgccaaa
     2461 tcaccaaccc aataacccct atacttatag tgagcaaata ctttctaacc ttgaagaaac
     2521 ggttgattat taccaagtag tagttgagcc aacaatgatt gatagtgctg gtaacatgtc
     2581 aaacggtgtt atttcagagt tcttaaagga aattagtatc agagccctca cgaaaaagca
     2641 ccaaaaaaat atcattatcg aacaaatgat ggtatacttt ttacatgcta ttcaaattga
     2701 ggatgaatta aaaatatatc ctaaaatcat tactgaaaat agacgaagca gcaccattga
     2761 tattgaaatt tttgtggatg atcaagtgat tgctaaagct attattacaa cgaaaataaa
     2821 ttagaggagt aacaaaacaa tgataacatt aaaatcagcc cgtgaaatag aagcgatgga
     2881 tagagcagga gacttcttag caggtatcca tattggctta agggatatta ttaagcctgg
     2941 tgtggatatg tgggaagtgg aagcatatgt tcgtcgccgt tgtaaagaag acaacgttct
     3001 tcctttgcaa ataggggttg atggtcacat gatggactat ccttatgcga cctgttgtgg
     3061 tctaaatgac gaagtagcac atgcctttcc ccgtcattac attctgaaag aaggggattt
     3121 gcttaaagtt gacatggtac tcagtgagcc tttggataaa tcaattgttg atgtagcagc
     3181 tttagatttt gataatgtgc ctgagatgaa gaaatggaca agatcttata ctggtggttt
     3241 agctgactct tgttgggctt atgctgttgg aacaccgtct gacgaaataa agcaattaat
     3301 ggatgtcacc aaagaagcca tgtaccgtgg tattgaaaaa gcagtaattg gcaatcgtat
     3361 tggtgatatt ggcgcagctg ttcaagaata cgctgaaagc ttcggttatg gtgtcgtgcg
     3421 tgatcttgtt ggtcacggtg ttggtcctac aatgcatgaa gagccaatgg taccaaacta
     3481 tggaacagca ggtcgtggac ttcgtctaaa agaaggcatg gtcttgactg ttgagccaat
     3541 gattaataca ggaacttggg aaattgatac cgacatcaag acaggttggg ctcataaaac
     3601 cctagatggt ggtttatctt gccaatacga acaccaattt gtgattacta aagatggtcc
     3661 cgttatttta acaagtcaag gagaagaaag aacttactaa aatggcagaa aaaaaatggt
     3721 ttgataaggt actgtccaag tggcagtatg aacccattca agtctttatg aggcatttac
     3781 aaagtgcaga aatggattta tctgccattg cggttgcgta ttaccttatc ttaacggcct
     3841 ttccattaat tgttattgca gccaatattt ttccttacct caatattgat attgctgatt
     3901 tgttacgttt aatgaagcaa aatttgccta aagatatttt tagaccggct tctgcaattg
     3961 tagaaaatat tttctctaaa ccgtctggaa gtgttttggg agtagcgact ttgacaggat
     4021 tatggacaat gtctcgaagt ttgacatcgc tgcaaaaagc tattaataaa gcctatggcg
     4081 cttctcagca tcgagatttc tttatcggac acttggttgg tttgttgacc agtttaatta
     4141 ttttattttt attagccttt gccttaatct tttcaacatt ttctaaagct gctattcaag
     4201 tgctggataa gcattaccat ttgagtgata atatcacaac gattttctta ctcctcattc
     4261 aacctattac agttttgatt atttttgttg gcttgatgct actatatttt ttattaccca
     4321 atgttaagat taaaaaaatt cgctacattt taccaggaac cctatttaca tcttttgtga
     4381 tgacattttt gagtaatctg gttggcaatt acgttgtgta taatgttgag cggatggtag
     4441 atattaaaat gtttggttca gttatgattt ttatcatcat gctatggttt attttcttag
     4501 caagaatcct gattttagga gctatattta atgcgaccta tcaagaaatg tccttgggga
     4561 aattagaagg tcgtagtggt gatatgatcg ctatccttaa aaaaacactt gggaatgatt
     4621 cagatctatc tccttcacag tctatcgaag atagtcacac tgattgatac aaaaaagata
     4681 ataagtcgtg gagtgagaaa ctattttctt gcttcatttt ttatgaggat aaatagaaaa
     4741 tcattgatct tagcaaatag aaaggcagat aaaacggatg aaattgcgaa caaatgcagg
     4801 accattacag ggaacgattc aagttccagg agacaagtcc attagtcacc gggcagtcat
     4861 attaggagct gttgctaaag gggaaacacg agtaaaagga ctcttaaaag gagaagacgt
     4921 gctttccacg attcaagcct ttaggaattt gggggtccgt atcgaagaaa aagatgacca
     4981 gcttgtgata gaaggtcaag gttttcaagg attgaccgct ccttgtcaga cacttaatat
     5041 gggaaattct ggaacctcta tgcgcctcat tgctggctta ttggcaggtc aaccttttag
     5101 tgtcaaaatg attggcgatg aaagcttatc caaacgtcct atggatcgga ttgtttatcc
     5161 gttaaagcaa atgggggttg agatatctgg agaaacagat aggcaatttc ctccactaca
     5221 attgcaaggt aatcgtaatt tacaaccaat cacatatact ttgcctatct cttctgctca
     5281 ggttaagtca gctattttgt tagcagcttt gcaagcaaaa ggaacaacac aggttgttga
     5341 aaaagagatt actcgaaacc atacagaaga aatgattcaa caatttggtg gacgattgat
     5401 agttgatggt aaacgcatta ctttggtggg accccagcag ctcactgctc aagagataac
     5461 tgtccccgga gatatttcta gtgcagcttt ttggcttgtc gccggcttaa ttattcctgg
     5521 ttcggagctc cttttaaaga atgttggagt caatccgaca cgaacaggga ttcttgaagt
     5581 ggttgaaaaa atgggagcac agattgtcta tgaagatatg aataagaaag agcaagtaac
     5641 tagtattcga gtggtatatt ctcacttgaa aggaactatc atatcaggag gtcttatccc
     5701 tcgattgatt gatgaacttc ccatcattgc acttcttgca acccaagcac aaggaacaac
     5761 ctgtattaaa gatgctcaag aattacgagt caaagaaaca gatcgtattc aagtagtaac
     5821 tgatattctt aacagtatgg gagctaatat caaagcgaca gcagatggca tgattatcaa
     5881 aggccctacg gtactatatg gggctaacac aagtacctat ggagatcatc gtattggtat
     5941 gatgacagca attgcagcct tgcttgttaa acaaggacag gtccatttgg ataaagaaga
     6001 agccatcatg acgtcttatc caacgttttt caaagattta gaaaggctgt gtcatgacta
     6061 aagtgttatt gggatttatg ggagtgggga aaacaacggt ttcgaaacac ctaagtatgc
     6121 actgtaaaga tatggatgct attattgaag ctaaaatcgg tatgtctatt gcagcttttt
     6181 ttgaacagta tggagaaata gcatttcgaa caattgaaag tcaagtgtta aaagatctat
     6241 tgtttgcaaa tgataatagt atcatcgtaa caggtggcgg tgtagtggtt ttacaagaaa
     6301 atcgacaatt actgagaaaa aatcaccagc ataatatttt attggtagct tcttttgaaa
     6361 ctttgtacca gcgtttaaaa catgataaaa agtctcaaag acctctattt cttaagtact
     6421 ctaaggaagc attttatgaa ttttatcaac aacgtatggt attttatgag ggactttcag
     6481 atttagtaat cagagttgac catcgtacgc ctgaagaagt tgccaacatc attgagggtt
     6541 attagtaggt cattgtcgta atctgatatt tatggtttta aacaggtatc tgtctaaagc
     6601 acttcttatg gcaagttggc tttattaaat attaggaaat aatcttgatt attctataat
     6661 gattaaaatt ttgagaggac aatctggcta atataggtta taatggtagt attcgttaaa
     6721 agtgcaattg taatactaag agatgataag atatgacaaa ataccccatg ggtggcctta
     6781 gtcaccatga agaattacgt tatttttatc tcctaaggaa tttgagttac cttagtgaga
     6841 atgaaaaaaa agagtttgct tttttaaaat ctaaattgga aattggtcga gcttatgctc
     6901 cttctaagca gcattatagg aagtcaaaac ggcaagaacc ttactttgaa gatgactact
     6961 ataacgacta ctcaccaaat gatttactag aagatgatga cgtcaatcat gactcttctt
     7021 ttgttccata tggtttaccg atatatccta aagaagacag atatttaaac aaaaaaacaa
     7081 aacttacagc tcgtagacct atagatactc cgcagcctat tgatgaagac gatgcttttt
     7141 taacagagtc tgttgctcgt tgtgctcttc ctagatctca aaaaagaaag cataagaaaa
     7201 aaggatgtat gaaatggttt tttaacattc ttggcttatt gctaatgact gtgcttatgg
     7261 ggttagggtt gatgtttgca aaaggggttt ttgatatttc tactaataaa gctaattaca
     7321 aaccagctgt ttcccaagct tttgatggtc aagaaactca agatggtacg aacattctgg
     7381 ttttgggttc tgaccaacga gttactcaag gttctacaga tgctcgcaca gataccatta
     7441 tggttgtcaa tgtcggcaac catgctaaaa aaataaaaat ggtctctttt atgcgtgaca
     7501 ctttgattaa cattccagga tacagttata atgataattc gtatgatctt aaattaaata
     7561 gtgcatttaa tcttggagag caagaagatc accacggagc agagtacgtt cgacgggcct
     7621 taaaacataa ttttgatatc gacattaagt attatgtgat ggtagatttt gaaacatttg
     7681 cagaagctat tgacaccttg tttccaaatg gtgttaagat tgatgccaaa tttgcgacag
     7741 taggtggtgt agctgttgac tccgtagaag ttccagatga cctgcgaatg aaaaatgggg
     7801 ttgttcccaa ccaaaccatc gaagttggag aacaacgcat ggatggtaga accttgctca
     7861 actatgctcg tttccgtaaa gatgacgaag gagatttcgg acgaaccgtc cgtcagcaac
     7921 aggttatgtc agctgttatg tctcaaatca aagacccaac taaactcttt acagggtctg
     7981 cggctattgg taaaatctat gcgctgactt cgaccaatgt ttcttttcca tttgttgtta
     8041 aaaatggtgt ttctgtttta ggaagtggga aaaatggagt tgagcacgtg accatcccag
     8101 aaaacgggga ttgggttgac gaatacgata tgtatggagg acaagccctt tacatagatt
     8161 ttgataagta tcagaaaacg ttagccaaat taggtctgcg ctaagatatg gtataatgga
     8221 gagtaactaa agttgctctt cttttttgag caatggttag ccctagaaaa ggaaaaagaa
     8281 taagaatgtt gaaaaaaaat gatattatcc aagttgctat ttcagattta agccatgagg
     8341 gagcaggtgt cgctaaacac gatggttttg ttttctttgt tgataatgcc ttgccagaag
     8401 aagtgattga catgcgtgtc ttaaaggtca ataaaaacag cggttttggc aaagtagaag
     8461 cctatcatta cctgtcgcca gctagaaatg cagatgtcaa tttaacttat ttgcgaacag
     8521 gcattgcaga ccttggacat ctaacttatg aagaccaact gactttcaaa aagaaacaag
     8581 ttcaggacag cctctataaa attgctggaa tcagtgacgt gacagtcgaa agcacgattg
     8641 ggatgacaga acctttagct taccgaaata aggctcaggt tcctgttaga cgtgttaatg
     8701 gtcagctaga aacaggcttt ttccgcaagc attctcatga cttgattcct atttcggatt
     8761 attatattca ggacaaagag attgatcgtc tcattaattt tacccgtgat ttattacgcc
     8821 gctttgatat taaaccgtat gacgaaacag aacaaacagg tctcttgaga aatattgttg
     8881 ttcgccgagg ccattactct ggagaaatga tgctggtctt agtgactaca cgcccaaaag
     8941 ttttccgtgt tgaccaagtc attgaaaaaa tcgttgaagc ttttccagca gtggtgtcta
     9001 ttattcaaaa tattaatgat aagaacacca atgcaatctt tggtaaagat ttcaaaacgc
     9061 tttacggcaa ggataccatt actgatagca tgcttggaaa caactatgcc atttctgccc
     9121 agtctttcta ccaagtgaat acggttatgg cagaaaaact ctatcaaaca gctatagcct
     9181 tttcagacct ttctaaagat gacattgtga ttgacgccta ctcaggtatc ggaaccattg
     9241 gcctatcatt tgctaaaaca gttaaagctg tttatggtgt tgaagtgatt gaagcagctg
     9301 ttagagatgc tcaacacaat gccgctctta atggcatcac caatgcctac tttgtcgcag
     9361 ataccgcaga acatgccatg gcaacatggg cgaaagatgg cattaaacca agtgttattc
     9421 tggtagaccc gccacgaaaa ggcttaacag aaagtttcat ccaagccagc gtggcaatgg
     9481 gaccacaaaa aattacctac gtttcctgca acccagccac catggcgcgt gacatcaagc
     9541 gttatcaaga gttgggttac aaactggcca aagtacagcc cgtagatttg tttccccaga
     9601 cgcatcacgt ggagacggta gcacttttgt ccaaacttgg tgtcgataag catataaata
     9661 ttgaaattga gatggatgag cttgatttga caagtgctga aagtaaggca acatatgctc
     9721 aaatcaaaga atatgtttgg aataaatttg aattaaaagt ttcgacatta tatattgcac
     9781 agataaaaag gaaatgtgga atagaattac gagaacatta caacaagtct aaaaaggaga
     9841 aacaaattat tccacagtgt acacctgaaa aagaagaagc catcatggat gctttgagac
     9901 atttcaaaat gattgaatag aaaagaatga cagcatatca ctttctgcat ttattacatt
     9961 cctatttggt ataagaacaa ctattattct tttcttgcaa ggtatcaatt agaaaatagg
    10021 gtcaatataa agaatggtag gataatacct atatataaac catggaggta ggcatatgag
    10081 gtcttatgaa agtaaggaag aattaaagaa tgagataaag aaaacttttg aaaaatatat
    10141 ttcagagttt gacaatatac cagaagaact aaaagataaa agactagaag aagttgatag
    10201 gacaccagca gaaaatcttg cctatcaagt aggctggacg actttagtat taaaatggga
    10261 agaagatgag aaaaaaggta tagatgttaa aacaccatca gataaattca agtggaatca
    10321 acttggagaa ttatatcaat ggtttacaga tacctatgcc cataaatctc tatatgaact
    10381 aaaagaacaa ctaacagaaa atgtaaaaaa aatttatctt atgatagatg aattaacaga
    10441 tgaagaatta tttaaaccac atatgagaaa atgggcagat gaagcaacca aaactgctac
    10501 ttgggaagta tataaattta ttcatgtaaa tacagtagcg ccatttggaa catttaggac
    10561 taagattagg aaatggaaga aattagttct atatatagaa aagtataaat aagtttactt
    10621 aggaggattt tatggcagtt gcaaagatca aagttacatt aaattgccca atagaaaaag
    10681 tatgggataa agttactgac cttcgtgatt ttagttggag aagtgatatc aaagatatca
    10741 aaattattg
//
LOCUS       DATWVB010000047        10619 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.047, whole genome shotgun sequence.
ACCESSION   DATWVB010000047 DATWVB010000000
VERSION     DATWVB010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10619
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.047"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            87..608
                     /locus_tag="VCX65_001516"
     CDS             87..608
                     /locus_tag="VCX65_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP5053970.1"
                     /translation="MTKDRQIKKTKTAIYSAFLALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLELIK"
     gene            823..1341
                     /gene="rimM"
                     /locus_tag="VCX65_001517"
     CDS             823..1341
                     /gene="rimM"
                     /locus_tag="VCX65_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEP5053971.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DQFVQEVTIVSHRKQKHFDIIKLKDMYHINAIEKYKGYTLKVSKANQGDLQEGEFYYH
                     QIIGMAVYEKDRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLNVDVPNKRV
                     DVELMEGLDDED"
     gene            1331..2062
                     /gene="trmD"
                     /locus_tag="VCX65_001518"
     CDS             1331..2062
                     /gene="trmD"
                     /locus_tag="VCX65_001518"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEP5053972.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLL
                     ERYDFSEEERKLLDKIKEALGQGED"
     gene            2062..3054
                     /locus_tag="VCX65_001519"
     CDS             2062..3054
                     /locus_tag="VCX65_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEP5053973.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGVELTENLIKQLNRFEDRITICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLTTSTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            3233..4291
                     /locus_tag="VCX65_001520"
     CDS             3233..4291
                     /locus_tag="VCX65_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEP5053974.1"
                     /translation="MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            4304..5227
                     /locus_tag="VCX65_001521"
     CDS             4304..5227
                     /locus_tag="VCX65_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEP5053975.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     VVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPNNQDAGHQV
                     ADLLNKANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
     gene            5483..6196
                     /locus_tag="VCX65_001522"
     CDS             5483..6196
                     /locus_tag="VCX65_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP5053976.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKTIAQRASQFIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGIDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            6193..7104
                     /gene="pfkB"
                     /locus_tag="VCX65_001523"
     CDS             6193..7104
                     /gene="pfkB"
                     /locus_tag="VCX65_001523"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEP5053977.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETEIN
                     GQGPVISREQLEDLKTKLSQLTAEDTVVFAGSAPANLGNAVYKELFPLVRQSGAQVVC
                     DFEGQTLIDALTYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            7101..9047
                     /locus_tag="VCX65_001524"
     CDS             7101..9047
                     /locus_tag="VCX65_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP5053978.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGNTYHAKNGKSET
                     AVSTEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSY
                     HEIAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            9140..9739
                     /locus_tag="VCX65_001525"
     CDS             9140..9739
                     /locus_tag="VCX65_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEP5053979.1"
                     /translation="MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYNTKLNELIEWYQLTNFDGLMK"
     gene            9891..10598
                     /locus_tag="VCX65_001526"
     CDS             9891..10598
                     /locus_tag="VCX65_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEP5053980.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
BASE COUNT         3291 a         1736 c         2288 g         3304 t
ORIGIN      
        1 tctattatct aaaagttaaa atacaattac tataaccaaa aatgagcacc tgttcaatag
       61 tgaacaacat ttagaaagtg tccgatatga caaaagacag acaaatcaaa aaaacaaaaa
      121 cagctatcta tagtgctttt cttgctttat tacaaaaaaa agaatattcg aaaataactg
      181 ttcgagatat gattacactt gctaatgtag ggagatcaac cttttatgca cattatgaaa
      241 gcaaagaaat gttactaaaa gaactctgtg aagaactttt tcatcatttg tttaggcaaa
      301 aaagaaatgt gacttttgag gactatttgg tacatatttt aaagcatttt gaacaaaata
      361 aagacagcat tgcgacgttg ttactttcta atgatcccta ttttttatta agatttaaaa
      421 acgaactaga acatgatgtt taccctaact tgcgctgcaa gtatatcgac aaaacgacta
      481 ttccagaagt attcctgaaa caatttgttc tatctagttt tatagaaacc ttaaaatggt
      541 ggctccatca aaggcaaagg atgtctgcaa atgaactatt aaagtattat ttagagctca
      601 taaaataatg actagtgagt catcttgcca aattcaattt tttaatacag acggatttta
      661 acaatttaac agagaaagac aaaactgtaa gtgcaaaata gactataacg tgataaaata
      721 ataggtaatt tggttctgaa aaagaagtgt ctatcaaact ttagaatcaa gagaggtcgc
      781 taaagtgacg tgagataaag agttaacgat ttaggagcta ccatggaata ttttaatgtt
      841 ggaaaaattg tcaacacgca aggcctgcaa ggagagatgc gcgtgttgtc tgtcagtgat
      901 tttgctgagg agcgctttaa gaagggatcg caattggctt tgtttgatga caaagaccag
      961 tttgttcaag aagtgacaat tgttagtcac cgtaaacaaa agcattttga tattatcaaa
     1021 ttgaaagaca tgtatcatat taatgcgatt gaaaaatata agggctatac gttaaaagtg
     1081 tcaaaagcta atcaaggaga cctgcaagaa ggagaatttt actaccatca gattatcggt
     1141 atggctgttt atgaaaagga ccggttgatt ggctatgtca aggaaatctt gcagccaggt
     1201 gctaatgatg tttgggtagt gaaacgccaa ggaaaacgag acttgctctt accatatatt
     1261 cccccagtag ttcttaacgt agatgttcct aacaagcgcg tagatgttga attgatggaa
     1321 ggcttagacg atgaagattg atattttaac cctttttcct gaaatgtttg cccccctaga
     1381 acattccatt gtaggcaaag caaaagaaaa aggattactt gacattcact accataactt
     1441 tcgagattat gctgaaaaag ctcgtcatgt ggatgacgaa ccctatggtg ggggccaagg
     1501 catgttattg agagtacagc ccatttttga caccattgaa cagattgaag ccaaaaaacc
     1561 aaggattatt cttttagatc cagcaggtaa accctttact caggcttatg ctgaagaatt
     1621 agctcttgag gaagagttaa tttttatttg tggtcattat gaaggttatg atgagcggat
     1681 taagaccttg gtgacggatg aaatttcatt aggtgacttt gtattaacag gaggtgagtt
     1741 ggcggccatg actatggtgg atgcgactgt caggttaatt ccacaggtac ttgggaaaga
     1801 aagtagccat caggacgatt ctttttcatc aggactttta gaataccctc aatacacaag
     1861 accttatgat tatcgtggta tgacagttcc agatgttcta atgagtggtc atcacgaacg
     1921 tattcgcttg tggcgtctag aagaaagtct cagaaaaacc tatttgagaa ggccagattt
     1981 gttagagcgg tacgattttt ccgaggaaga gcgcaagcta ttggataaga ttaaagaagc
     2041 attgggtcaa ggagaagatt agtgaaagat aaagcatatg atattacgat tattggtggt
     2101 ggtccaatag gtttatttgc agccttttat gcaggtctta ggggcgtaac agtaaagatt
     2161 attgagagtt tgtcagaact tggtggacag cctgccattc tttatcctga gaaaatgatt
     2221 tatgatattc cagcttatcc atctttaaca ggtgttgagt tgacagaaaa tttaataaaa
     2281 caattaaacc gttttgaaga tcgtataacc atttgtttaa aagaagaagt attaaccttt
     2341 gacaaggtta aaggtggttt ttcgattagg actaataagg cagagcattt ttcaaaagcc
     2401 attatcattg cttgtggaaa tggcgctttt gcaccaagaa ctttagggtt agaaagtgag
     2461 gaaaactttg ctgatcataa ccttttttat aatgttcacc agttggacca gtttgcggga
     2521 caaaaagttg tgatttgtgg tggtggagat tcagcagttg attgggcttt ggctttagaa
     2581 gatattgctg agagtgtgac ggttgtgcac cgtcgtgatg ctttcagagc acatgaacac
     2641 agtgtggaat tattgacaac atcaacggta aacctcttaa caccttatgt gccaaaagca
     2701 ttgaaaggaa ttggaaacct ggctgaaaaa ttagttattc aaaaagtgaa agaagatgaa
     2761 gtgttagaac ttgaattgga cagtcttatt gttagttttg gtttttcaac ttctaataag
     2821 aatttgaaaa attggaatct cgactataag cgttcaagta ttactgtttc accacttttt
     2881 caaacaagtc aagaaggtat ttttgccatt ggtgatgcag ccgcttataa tgggaaagtg
     2941 gatttgattg ctactggttt tggcgaagca ccaacagcag ttaatcaggc cattaactat
     3001 atttatccag atcgagataa ccgtgtggtg cattcaacct ctttaattga ctaagggagt
     3061 cggaagtttc aagagcagta gcaacagcta atattcagtt tgtcaggaga ggacaaatgg
     3121 ttttttacct aagtcttcgt gacaagtttt atactttgtg ataaaatagt cattgtgaaa
     3181 aaagtgtgat ggttttcaca gattaacaca ttacaatgaa aaggggtcta tcatgacaac
     3241 aacagataaa gagacattta gttcttttat gaataaggtc ttggctggta cagcgattgc
     3301 tatcgttgtg gcactcattc caaatgctat tttagcgact ttcttaaaac cgcttttgcc
     3361 aaacatggca gctgctgaat ttttacacat tgtgcaagtc ttccaattct tcacgccgat
     3421 tatggctggt ttcttgattg ggcaacaatt taagtttaat cctatgcaac agttggctgt
     3481 tggtggagct gcttatatcg gttctggggc ttgggcttat acagaagtca ttcaaaaagg
     3541 tgtggcgaca ggaacattcc aacttagagg tattggggac ttaatcaata tgatgattac
     3601 agctagcctt gcggttttag ctgtgaaata ttttgggaat aaatttggct ctttaaccat
     3661 tatcttgtta cctatcacta taggaactgg cgtaggttat attggttgga aatttttgcc
     3721 ttatgtgtct tacgtgacaa ccctgatcgg acaaggtatt aattctttta caaccttaca
     3781 acctatttta atgtctattt taattgcagt tgctttctcg cttatcattg ttagtccgat
     3841 ttcaactgtt gcaatcggtt tagctattgg gcttaatgga atggctgcgg gagcagcttc
     3901 tatgggaatt gcatcgacag cagcagtctt agtgtgggcg acgcttaaag ttaataaatc
     3961 tggtgtacca attgctatcg cacttggggc tatgaaaatg atgatgccaa acttcttgaa
     4021 acatcctatc atggctattc cgatggtgtt cactgcagca attagctcat taacagtacc
     4081 attgtttaat cttgttggaa caccagcttc atctggtttt ggcttagttg gtgcagtagg
     4141 tccgattgct tctttagcag gtggtagctc aatacttatt attatccttg cttggatcat
     4201 tgttccgttt gcggttgctt ttgcggcgca taaggtttct aaagatattc taaaacttta
     4261 taaagaagac attttcgtct ttgaaggcta ataggaggaa aatatgttag tttatattgc
     4321 tggctcagga gccatggggt gccgttttgg ttaccaaatt tcaaaaacaa ataacgatgt
     4381 gattttgtta gataactggg aagatcatat caatgccatt aaagaaaacg gtttagtggt
     4441 gacaggggat gtggaagaaa cagttaagct tcctattatg aaaccgactg aagccactca
     4501 agaagccgat ttgattatct tgtttacaaa agcaatgcag ttgccacaaa tgcttcaaga
     4561 cattaaaggc attattggaa aagaaaccaa agtgctttgc cttttaaatg gtcttggaca
     4621 cgaagacgtt attcgtcagt acattccaga gcacaacatt ttgatggggg tcactgtctg
     4681 gactgctggt ctagaaggac caggtcgtgc tcatcttcaa ggagttggtg ctcttaactt
     4741 acaaagtatg gatccaaaca atcaagatgc gggacatcaa gtagctgact tgttaaataa
     4801 agctaactta aatgcgactt atgatgagaa tgttgtgcca aacatctggc gaaaagcttg
     4861 cgtgaatggt accatgaatt cgacttgtgc tcttttagat tgtacgattg gcgaattatt
     4921 tgccagtgaa gatggtctca aaatggtaaa agaaatcatc catgagtttg ttatcgttgg
     4981 tcaagcagaa ggtgtcgaac taaacgaaga agaaatcaca caatatgtaa tggatacatc
     5041 tgttaaagct gctcaccatt acccatcaat gcaccaagac cttgtgcaaa atcaccgatt
     5101 gactgaaatt gattttatca atggtgcagt caataccaaa ggtgaaaagc ttggtatcaa
     5161 tactccatac tgccgtatga ttacagaact agttcacgct aaagaagcag tgttgaacat
     5221 ccaataaacg ctatcaaatc gttatactca atattatggc taaagcttta atattgagtt
     5281 ttttgttatg ctgatagtat ttttcttagg cgtcattatt tgtgagccta gattatgagt
     5341 taataaaaga aataataatt ggtagaattt gatagatttt gaaaggttat gcttgacttt
     5401 tagttataaa atagtataat aattgtaaac gatttcagtt aggggtggtt ctatcttaaa
     5461 atcaaaacga aaacaattaa tcatggcaaa gatcactgaa gaaaactatg tttctttaga
     5521 ggatttaatg caattactca actcctctga gtctactatc cgtagagatc taggagagtt
     5581 ggagcaagaa ggacggctac atcgtgttca tggaggtgct gaactttttc actctttaca
     5641 agaggaactt tctaaccaag aaaagtctgt caaaaacagt catattaaaa aaactattgc
     5701 gcaaagagcc tctcagttta tctatgacaa cgatgtgatc tttattgatg ctgggacaac
     5761 gactgaattt ttattacctt ttttacaagc taaaaattta actgtagtta ctaattctat
     5821 tcatcatgct gctagattag ttgaactctc tattgagacg attattgtag gtggttatgt
     5881 caaacaaacg accgatgcca gtattggtaa tgtagctttg gaacagatta ggcagatgaa
     5941 ttttgacaag gcatttcttg gaatgaatgg tattgatgat tcttacctga cgactcctga
     6001 tatggaagaa gcagttatta aaaaagcggt tctgtcaaat gcaaaattag cttacatttt
     6061 agtagatggc actaaaattg gtcaggtatc gtttgtaaaa gtagctccta ttaatgatgt
     6121 gactattatt acattaggag gatcagcaag tattcttaaa caaataaagg aaaaggcaaa
     6181 ggtgattgaa ttatgattta taccgtgacc ttaaaccctt ctattgactt tattgtcaga
     6241 attgaccaaa taaatcttgg gtcagtgaat cgcatggcga gtgatgataa gtttgctgga
     6301 ggtaaaggca ttaatgtgag tcgcatcttg caacgtttag acattgctag cacggcgaca
     6361 ggattcttgg gtggttttac aggacgtttt atcgaagaaa gtttgagtgc agaaggcgtt
     6421 aaaactgatt ttgtaaaagg tgatcaagat actcgaatca atgttaaaat caagtcacaa
     6481 gaagagactg aaataaatgg tcaaggacct gtcattagtc gggaacaact agaggatttg
     6541 aaaactaagc tttcccagct aacagcagag gatacagttg tctttgcagg ttcagcgcca
     6601 gctaatcttg gcaatgctgt ttataaggaa ttatttcctt tagttaggca aagcggtgct
     6661 caggtggttt gtgattttga aggacagact ttaatagatg cgcttacata taatcctctg
     6721 ttggttaaac ctaataatca tgaactagaa gctatttttg gtacgattct gactagtctt
     6781 gatgatgttg aaacctatgc ccgtcgtctt ttagagatgg gtgctcaaaa cgtcatcatt
     6841 tcaatggctg gtgatggtgc tttgctggtt actaaagaag cgacttattt tgctaaaccg
     6901 attaagggag aagttaaaaa ttctgtcggt gctggtgatt cgatggttgc tggctttaca
     6961 ggcgaattta tgaagagtca aaatccaata gaagccttaa aatggggcgt ggcttgtggt
     7021 acagcgacgg ctttctctga tgacttggcg acaattgcat ttattaagga aacatatcat
     7081 aaagttgagg tagaaaaacg atgaaaattc aagatttatt gagaaaagat attatgattc
     7141 tcgatttaca ggctatttct aaagaagttg ccattgacga gatgattact aaattagttg
     7201 aaaaagatat tgtacatgat tttgatgtct ttaaaaagag tatcatgaca cgtgaagaac
     7261 aaacatcaac agggcttggt gatgggattg ccatgcctca ttctaaaaat attgtagtag
     7321 ataaaccagc ggtcttgttt gcgaaatcaa ataaaggtgt ggattataag gctttagatg
     7381 gtcaaccaac ggatctcttc tttatgattg ctgcgcctca aggagcaaat gatactcact
     7441 tggctgcgct agcagaatta tcacaatacc ttttgaaaga cggctttgct gataaacttc
     7501 gtgctgcagc gacaccagaa gcagtcattg ctgtttttga tgaagcgtca acagctaaag
     7561 aagaagtggt tgctccaaca agtggtcaag actttatcgt tgctgttaca gcttgtccga
     7621 caggaattgc tcacacttat atggcagaag aggctttgaa aaaacaagct gcagaaatgg
     7681 gagtagctat taaagttgaa acaaacggtg cttctggtgt ggctaatcgt ttaaccgctg
     7741 aagatattca gagagctaaa ggagttattg ttgcagctga taaagcggtt gaaatggacc
     7801 gttttgatgg taaacaattc attgctcgcc ctgttgcaga tggtatcaag aaaagtcagg
     7861 aattgatttc tttgatttta aacaatgaag gaaacactta tcatgctaaa aatggaaaat
     7921 ctgaaacagc agtatcaact gagaaaacaa gtttaggcgg tgctttctat aaacacttga
     7981 tgggcggtgt ctcacaaatg ttgccatttg ttattggtgg cgggattatg attgctctag
     8041 catttttatt ggataacatg cttggtgtgc caaatgatca gcttggaagt cttggatcct
     8101 atcatgaaat agcagctatt tttatgaaca ttggtggagc agccttttcc ttcatgttac
     8161 cagtactagc aggttatatc gcttattcta ttgctgaaaa accgggctta gtagctggtt
     8221 ttgtggcagg tgccattgcc tcaaatggtc ttgcttttgg taaggtacca tttgcagcag
     8281 gaggagaagt gagcttggga ttaacgggcg tgccatcagg tttccttggg gcgcttgtgg
     8341 gtggtttcct tgccggtggt gttattcttg cccttcgtaa attgttggca ggcctaccac
     8401 gttctctaga aggggttaaa tctatcctcc tttacccatt acttggcgtc cttgtcactg
     8461 gtttcttgat gctttttgtc aatattccaa tggcagctat taacacagct cttaatgatt
     8521 tcttacaagg tctttcagga agctctgctg tccttatggg acttcttgtt ggtggaatga
     8581 tggctgttga catgggtggt cctgttaata aggcagctta tgtttttggt acaggaactt
     8641 tagcagctac tgtggcaaat ggtggttcgg tcgttatggc cgctgttatg gcaggtggta
     8701 tggtacctcc tcttgctgtt tttgtagcca ctctcttgtt taaagataaa tttaccaaag
     8761 aagaacgcga atcaggtttg accaacattg tcatgggact ttctttcatc actgaaggag
     8821 caatcccatt tggcgcagct gacccagcgc gtgcaattcc tagctttatt gctggttctg
     8881 ccttgacagg agctcttgtt ggtttggctg gcattaaatt aatggcgcca catggtggta
     8941 tcttcgtaat cgctttaaca agcaatccaa tcttatatct tgtctttgtt gtgattggtg
     9001 cccttgtatc aggtatctta tttggcgctc ttcgcaaaaa agcctaaaag gtaaagaact
     9061 tttttcttac taaaactaga atctgtcaag gttctagttt tttgctatac tagagttaaa
     9121 ggataagaaa tgaggacctt tgaaggtgaa aaaaaggaga agaagggcta aatcatcagt
     9181 aaatcgactt gtcttagggt tagtattact taatctgatt gttagtatgt ggacactaaa
     9241 attgggaaac cagcgattag ctccgtatgc ggatcacgaa actctgacat ttgtcaggaa
     9301 gattagtcat gctgctcaat cagtcgctca aaagaaacag ttatacagtt cggtgatgat
     9361 ggctcaggcc attttagaat ccaataatgg caagtcacaa ctaagtcaaa aaccttatta
     9421 taattttttc gggattaagg ggagctataa agaacggtca gtcatttttc caactttaga
     9481 agacgatgga caagggaatc tttatcaaat tgatgctgct tttcgttcct atgggagcct
     9541 gacagcttgt tttttagatt acgcaagagt tttgaatgat ccactttatg acaaaaccca
     9601 caaaaagttt tggtctcatt atcaagatgc tactgcaacc ttaacaggca cttacgccac
     9661 tgatacaact tacaatacca aattaaatga attgattgaa tggtatcaac tcactaattt
     9721 tgatggtcta atgaaatagt tatccacaat tttaaaaaaa atcagaagaa atatgtcgat
     9781 ttcaagacaa aagttatcaa tctcattaaa ttatctgtgg aaaagttaat ttaaacgttc
     9841 gtgtgctata atagaaacat agaaaatgta taaaaaagga tatgtgaata atgacaaaaa
     9901 agaaaggtaa gcttgtactt atcagtcttt ttgttctagc agcttgttta ggagcttata
     9961 gtgcaatgag acaatctcat aaaacttcaa acgtgtcagc tgagactatc gccagttctt
    10021 caacccgaca ttttattgat gaaattggtc caactgctag tactattggt caagaacgtg
    10081 atctttatgc gtctgttatg atagcacaag cgattttaga atcaagtaat ggtaaatcaa
    10141 gtctaagtca agcaccttat tataattttt tcggtattaa gggtgcctat aacggttctt
    10201 ctgtgacgat gtcaacttgg gaagatgatg gtaatggcaa tacctatacg attgatcaag
    10261 cctttagagc ttatccaagt attgcagact cccttaatga ctatgcagac ttgctaagtt
    10321 ctagcactta tataggtgct agaaaatcaa acacgctatc gtatcaagat gctacagcag
    10381 ctctaactgg cttatacgct acagacacca gttataactt aaaactaaat aatattattg
    10441 caacctatgg tttgacggct tatgatgttg ctaatagctc agctcaagaa actggtctag
    10501 caacttcggg ttatgtttgg aatgagtatc gtcgtaatta cactgatgcg gagaccctag
    10561 cagttgatga ggcttgggct aaacgcatga cttattaatg taacactaac aacaatctg
//
LOCUS       DATWVB010000048         9470 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.048, whole genome shotgun sequence.
ACCESSION   DATWVB010000048 DATWVB010000000
VERSION     DATWVB010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9470
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.048"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            67..717
                     /locus_tag="VCX65_001527"
     CDS             67..717
                     /locus_tag="VCX65_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEP5053981.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
     gene            720..1388
                     /locus_tag="VCX65_001528"
     CDS             720..1388
                     /locus_tag="VCX65_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5053982.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYC
                     LLEK"
     gene            1397..2629
                     /locus_tag="VCX65_001529"
     CDS             1397..2629
                     /locus_tag="VCX65_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEP5053983.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSVMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
     gene            2922..3800
                     /gene="mvk"
                     /locus_tag="VCX65_001530"
     CDS             2922..3800
                     /gene="mvk"
                     /locus_tag="VCX65_001530"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEP5053984.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLVIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            3782..4726
                     /gene="mvaD"
                     /locus_tag="VCX65_001531"
     CDS             3782..4726
                     /gene="mvaD"
                     /locus_tag="VCX65_001531"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEP5053985.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSVSFLPDTATSDQFYINGVLQNDEEHTKISTIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            4719..5732
                     /locus_tag="VCX65_001532"
     CDS             4719..5732
                     /locus_tag="VCX65_001532"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEP5053986.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFSHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHSAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWEEN
                     DQP"
     gene            5719..6708
                     /locus_tag="VCX65_001533"
     CDS             5719..6708
                     /locus_tag="VCX65_001533"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEP5053987.1"
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(6938..8215)
                     /locus_tag="VCX65_001534"
     CDS             complement(6938..8215)
                     /locus_tag="VCX65_001534"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEP5053988.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQTGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(8202..9377)
                     /locus_tag="VCX65_001535"
     CDS             complement(8202..9377)
                     /locus_tag="VCX65_001535"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEP5053989.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRSKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTANPRILALNEDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQA
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHRRIYHTNDKN"
BASE COUNT         2977 a         1710 c         1920 g         2863 t
ORIGIN      
        1 aaataaagat aaccgatcat tgtagagatt taagcatttg ttgagaaaat ttgttataat
       61 aagcgtatga aagaaagact agaacattat tctaccagct ctatatatag cggatttgaa
      121 gtgtacttgc cgttggtact acagacaata acagatgtga ttattgctga gaatatcaaa
      181 agcaaaaaag aaacagggtt taaactatac gaacacttta catcccgtat taaatcggaa
      241 gcttcgatga ttgaaaaatg tcaacgcaaa caacttcctc taacaagcaa atctgcatta
      301 aaaatcatta aagatagtat cggtattcgc attatttgtg gttttattga tgatatttat
      361 cggatggtag acttgctcaa aagcattcct ggtatgtcag ttaacactga aaaagattat
      421 attttaaatg ccaagcctaa tggctataga tcatatcatc tcattttgga attagaaaca
      481 cattttccag atattttagg ggaaaaaaaa ggatgttatt ttatagaagt gcagttgcga
      541 accattgctc aagactcttg ggctagcttg gaacatcaaa tgaagtacaa acatcaagtt
      601 gctaatgcag aaatgattac aagagagtta aagcgttgtg cagacgagtt ggcatcttgt
      661 gatgttacca tgcaaaccat tcgtcaattg attcaagaaa cgacggagga agagtaacca
      721 tgaaaatttt gttagctgaa gacgaatggc agatgtctaa tgttttgaca actgccatga
      781 ctcatcaagg ttatgacgtt gatgtggttt ttaacggtca agaggcaatt gataaagcta
      841 aagacaatgc atatgatatt atgattttag atatcatgat gccgattaag tctggcattg
      901 aagctttaaa ggagattcgc gcttcaggaa attgctcaca tattattatg ctgacggcta
      961 tggcagaaat taatgaccgt gttactggac tagatgcggg agctgatgat tatctgacta
     1021 aaccgttctc attaaaagaa cttttagcta gattaaggtc gatggaaaga cgagtagaaa
     1081 gttttactcc tcaggtatta caatttgctg gtgtcacatt aaatattaat gagcaagaat
     1141 tgagtgccgg taatgctata cgattagctt ctaaagaagg taaattaatg gcctttttaa
     1201 tgttaaatca aggaaagtac ttggatacta aaacacttta ccaacatgtt tggtcagacc
     1261 aagaagatta tgatacttct attgtttggg tttatatttc ttatcttcgt caaaaattat
     1321 tagctattca agcaaatgtc attattgcag gtgataaaga tactagctat tgtttattag
     1381 aaaaatagga ggtgacatgt ttaatcgtat ccgtattcgt tttatcatga ttgcttctat
     1441 tgccattttt attattttaa gttcaattgt tggtattatt aacacggcac gctgttacca
     1501 aagtcaacaa gaaattaacc gtattttaca tttaatttcc tcaaataaag gtaaattacc
     1561 tggcactacg gaaagctcta aacgacttgg aacgaaactg tctgaagata gcctaagcca
     1621 gtttcggtat tatagtgtca tttttaatgc taatggacat ctactttctt ctaatactgc
     1681 taatatttca gctttagata gagaagaagc ccaatatttt gctagacttt ttgctaagtc
     1741 tggggaagaa aaaggcagtt accgtcacca agatagtgtt tattcgtact tgattactca
     1801 gctgccaaat gaagaaaaac tggttgtaat tttagatact accttttatt ttcgtagtgt
     1861 aggagattta ttagctgttt cagtgatgtt ggcctttgga ggatttatct tttttgttgt
     1921 tttagtgagt cttttttccg gtatggtcat caaacctttt gtccaaaatt atgagaagca
     1981 gcgtcgcttt attactaatg caggccacga gttaaaaaca ccactagcca ttatctcagc
     2041 caataatgaa ttggtcgaat taatgactgg agaatcagaa tggaccaaga gtacaagtga
     2101 tcaggtgaag cgattgacag gcttgattaa tcaaatgatt actttggctc gtttggagga
     2161 acagccagat gtggtattac atatggtaga cttttcagct attgctcaag atgcagctga
     2221 agattttaag agtctggttt tgaaagatgg taaacgtttt gatttgacga ttcagccgaa
     2281 tattatgatt aaagcggagg aaaagtcatt atttgaactt gtgacaattt tagttgataa
     2341 tgccaataaa tattgtgatc ctaaaggctt ggtcaaggta tctttaacca ctattggaag
     2401 aagacgaaaa cgagcgaaat tagaagtttc taatacctat ttggaaggaa aatccattga
     2461 ttacagccgc ttttttgaac gcttttatcg tgaagacgaa tcccataata gcaaagaaaa
     2521 aggctatgga attggtttat ctatggcaga aagtatggtt aagttattta aaggaacgat
     2581 aactgtaaat tataaaaacg atgctattgt ttttacagtg gtgatttaac ttaaacattt
     2641 ttcagtacct ttagctagta ataatgtcta ggcaaaggta ataaatgatg cttaaccagc
     2701 ccatgaggct ggttttaacg tttaatttag tagaagagtg attaaagaag gtagtttgaa
     2761 ataagaaaat ttttgttatg atcctaaaaa gagtagatag tctttattgt taatttcagt
     2821 gaagaaatga ttttaaaaag atatatcatc gcattttcta atcatttagt gtaaaatagt
     2881 aaggtaaaag tttagaagaa ttagtaatga aaagataaaa aatgaatgaa aacattggat
     2941 atggtaaggc acacagtaag atcattttga taggtgagca tgctgttgtg tatggctacc
     3001 cagctattgc tttgccttta acagatattg aggtggtttg tcatattttt ccagctgata
     3061 agccattggt ctttgatttt tatgatactc tatcaacagc catttatgct gccttggatt
     3121 atttgcagcg actacaagaa ccaattgctt atgagattgt ttcacaagtg ccacaaaagc
     3181 gtggtatggg gtcttcggca gccgtttcta ttgcagctat tagagccgtt ttttcttatt
     3241 gtcaagaacc cctctcggat gatttgttgg aaattttagt caacaaggca gaaattattg
     3301 cccacaccaa tcctagtggt ttagatgcca agacatgcct tagtgaccat gccattaagt
     3361 ttatccgaaa cattggcttt gaaactatcg aaatcgcctt aaatggttat cttgtcattg
     3421 cagatacagg gattcacggt catacacgtg aggccgtcaa taaggtagca cagtttgagg
     3481 aaacgaattt gccctatctg gctaaactag gagctttgac acaagccctt gaaagagcga
     3541 ttaaccaaaa aaataaggtg gctatcggtc agctcatgac acaagcgcac tctgctttaa
     3601 aggccattgg cgttagcatc agtaaagctg accaacttgt ggaggctgcc ctaagagcag
     3661 gtgctttagg cgctaagatg acaggcggtg gcttgggtgg ctgtatgatt gccctagcag
     3721 ataccaaaga catggccgaa aaaatcagtc acagattaaa agaagaagga gccgtaaaca
     3781 cgtggatcca aatgttataa ccgtaacatc ctatgctaac attgctatta tcaaatattg
     3841 gggaaaagag aatcaagcta agatgattcc ttcgacctct agcatttctt tgactttgga
     3901 aaacatgttc accacaacca gcgtttcctt cttaccagat actgcaacca gtgatcagtt
     3961 ttacattaac ggtgtcttgc aaaatgacga agaacatacc aaaatttcta ctatcattga
     4021 ccaatttcgc caacctggtc aggcttttgt aaagatggaa actcaaaata atatgccaac
     4081 agctgcaggt ttatcatcaa gttccagtgg cttatcagcc ttggttaaag cctgtgatca
     4141 attatttgac actcagctag atcagaaagc tttagctcaa aaggctaagt tcgcctcagg
     4201 atcatcttct cgttcttttt ttggcccagt tgctgcttgg gacaaagata gtggtgctat
     4261 ttacaaggtt gagactgact tgaaaatggc catgattatg ctggtcttaa atgctgcgaa
     4321 aaagccaatt tctagccgag agggcatgaa gttatgccgc gatacctcaa ctacatttga
     4381 tgaatgggta gaacaatcgg caatcgatta ccaacatatg cttacctatc tcaaaactaa
     4441 taattttgag aaagttggtc agttaacaga agctaatgcc ttggccatgc atgccacgac
     4501 aaagacagcc aatcctccct tttcttacct aacaaaagag tcttaccagg ctatggaggc
     4561 tgtgaaagaa ctgcgtcaag aaggttttgc ttgttatttt accatggacg caggtccaaa
     4621 tgtgaaggtc ctatgtttag aaaaagactt ggctcaacta gcagaacgac ttggcaagaa
     4681 ctaccgtatt atcgtttcaa aaacaaagga tttaccagat gtctaattat tgtgtgcaaa
     4741 caggtgggaa actatacctc acaggcgaat atgctatctt aacaccagga caaaaagcct
     4801 taattcactt tattccactg atgatgacag cagaaattag cccagcagcc catattcaat
     4861 tagcttcaga tatgttttcc cataaagcgg gcatgacacc cgatgcctct tatgcactga
     4921 ttcaagcaac ggttaaaacc tttgctgatt atctaggaca gtcaattgac caactggagc
     4981 cattttccct aattataacg ggaaaaatgg agcgcgatgg caaaaaattt ggcattggtt
     5041 caagtggtag tgtcaccctc ttaaccttaa aggccttatc ggcctattat cagatcactt
     5101 taaccccaga gttactcttt aaactagcgg cttatacctt gcttaagcaa ggagataatg
     5161 ggtctatggg ggatattgcc tgtatcgctt accagacttt agtcgcctat acctcctttg
     5221 accgagaaca ggtcagtaac tggctgcaga ccatgccctt aaaaaaactt ctcgtcaaag
     5281 attggggtta ccatatccaa gtcattcaac cagccctgcc ttgtgacttt ttggttggct
     5341 ggactaaaat acctgctatt tcaaggcaga tgattcaaca agtgacagcg agcattaccc
     5401 cagctttctt aagaacaagt taccagctaa cgcaatcagc tatggtagct ttgcaagaag
     5461 gtcataagga agaactcaag aaaagtttag caggagcaag tcatctccta aaagagcttc
     5521 attcagctat ctaccatcct aagctagtaa ccttggtagc tgcttgtcag aagcaagatg
     5581 ctgttgctaa atcttcaggt tctggtggtg gagattgtgg catcgcgctt gcctttaatc
     5641 agaatgccag agataccctt atttccaaat ggcaagaagc tgatatcgca ttactttatc
     5701 aagaaaggtg ggaagagaat gaccaaccgt aaagatgatc acatcaaata tgccctcaag
     5761 taccaatcgc cttataatgc ttttgatgac atagaactca tacatcattc cttacctagc
     5821 tatgatttgt ctgatattga tctcagtact cattttgccg ggcaagactt cgactttccc
     5881 ttttacatca atgccatgac aggaggaagt caaaaaggca aagctgtcaa tgaaaaattg
     5941 gccaaagtag cagcagcaac agggattgtc atggtgacag ggtcttatag cgctgcttta
     6001 aaaaatccta acgacgattc ctatcgttta catgaggtgg cagataactt gaaactagcc
     6061 acgaatattg gtctagataa acctgtggcg ctaggacaac aaacggttca agaaatgcag
     6121 cccctctttt tacaggttca tgtgaatgtg atgcaagagt tgctgatgcc agagggtgag
     6181 cgcgtctttc atacctggaa aaaacacctc gctgaatacg ctagtcaaat accagttcct
     6241 gtcattctca aagaagttgg ttttggcatg gatgtcaata gtatcaagct agcacatgac
     6301 ctaggcattc aaacctttga tatttcagga agaggaggga cctcatttgc ctatattgaa
     6361 aatcaaagag gaggagaccg ctcttactta aacgattggg gacaaaccac cgttcagtgc
     6421 ttgctaaatg cacaaggact gatggaccaa gtggaaatct tagcttcggg tggtgtcaga
     6481 caccccttgg acatgattaa atgtttcgtc ctaggagcac gtgcagtggg actctcacgc
     6541 accgttttag aattggtcga aaaataccca accgagcgtg tgattgctat cgttaacggc
     6601 tggaaagaag aattaaaaat cattatgtgt gctcttgact gtaaaactat taaagaatta
     6661 aagggagtcg actacttact atatggacgc ttgcagcagg ttaattaggc ttcatcacct
     6721 ctacaatagt gccacctact acaaagatga tagagctttt ttagaacata atataaaata
     6781 tttataaata cctcatcaaa ctcagaatag agtagatgag taaatagagt atgttatgga
     6841 gactatttct aagacttgta tgtatagaaa caaagattaa acacccatgt aaaccaattg
     6901 tttacatggg tgtttgcctt atattagttg tttaaatcta agactgtctt agctgggata
     6961 agtaaaaatg tgctttttct agatttattg gtttatcagc tagtaaagca ttaactaaag
     7021 gagcaatttc gtcttgggtt gcccccgcca aaagagctaa tgatttcgca tgtagtttca
     7081 tgtgaccagt ttggatgcca gatgaggtca gagcttttag tgcagcaaag ttttgagcta
     7141 accccacaga tgcaatcaat tgggctaatg ttttggcatc aggttgatta agaagatcat
     7201 gtgcgataga aacagtaggg ttaagcccga tagatccccc cttactagca ataggcatag
     7261 ggagggtcat ttggccaagc agaacttgtt tatcttggtc aaaatgccac tgactaagtc
     7321 cttgatagct accatttctt gaggcataag catgggcccc tgcttcaata gcacgccagt
     7381 catttcctgt ggctattacc actgcatcaa tgccattaaa aataccttta ttatgagtag
     7441 tagcccggta aggatctact tgagctagtc ggctggctag ctctattttt tgagctaact
     7501 gtagggattt tgttttatcg tgatctaaaa ggcgcacggg aatctcacaa ctagtagtaa
     7561 caagcgactc tgttgcgtaa ttagataaaa tcgccattag acaatgcccc ttagacagtc
     7621 ttgttaaatc aggaacaaga gcttccatca tagtattgac catatttgct cccatagctt
     7681 cttgggtatc aacagtcaga tagaaaatca aaaactctcc tttttcttcc aaatgaatgg
     7741 ttctagcgcc tccacctctt ttaacaatgg aaggataagc tttatttgcc aatgcaatta
     7801 gcttttttgt tttatgaagg atggcggctt tagcgttatc tatttggtcg atatcgtaaa
     7861 gaacaatttg accaatcatt tgtcggttta gggtttgagc tttaaaacca cctgagcgtt
     7921 tgattagttt tgctgcgaaa gatgctgcag caacaacaga aggttcttcc gtgacaaaag
     7981 gcatctgata agttgaaccg ttgacaagaa aatcaggagc tatgctaaag ggcaaagcca
     8041 atcgtcctaa gacattttca gtcatttgat tagctgtttg gataggcaaa agaacgtctg
     8101 ttttgagttg atttaagttt tcagcattaa gtagtttaaa tttttcgata agttggaggc
     8161 gttcttcgaa tgttttcttt gaaaaaccgc tccagttaag attagttttt gtcattggta
     8221 tgatagatcc ttcgatgctc cttgatggct gttagagcaa attttccagt taagtaaatg
     8281 tcaaaattgg cattaccatt atcatctaat tggacttgtt cgtagaaaag gtcttcgtat
     8341 ttagaaacgg aaagacgtgt tcgttgatcc agtaaagctt gtcgattagt cattaacatt
     8401 ttatcgtacc cagcaactaa ctgaccggaa taaaattcac ttacggcacc ggaaccatag
     8461 ctaaaaaaac caattttatc tccagattgt aatactttac tattttcaag taaagataac
     8521 aatcctagat aaagtgagcc agtataaata tttccaattt gtttgctata agtaatagaa
     8581 gcttgaaagg cttctattag tttttccctg tgttcaggag gtactgtgtt atccataatg
     8641 ttatttagac cttttagggc taacttggga aatggaatat ggaaacaaac tgcagcaaaa
     8701 tcagataact gaaggttttc tcttttctga taagcttgcc acgtggtttc taagcaattg
     8761 agatattgct tggtagagta aataccatca acataaggtg tgaaactata gttaggcctc
     8821 caaaagtcca taatatccct agtttgagcc acattatctt catttagagc aagaatacga
     8881 gggttagcag ttaccaaaag agcaatacta ccagagcctt gagttgattc gccaggagat
     8941 cctacaccgt atctagcaat atcactagca ataacaagga cacgagaatc tggcttagaa
     9001 gccacatgca gtttagcata gtctagagca gcagttgcgc tatagcaggc ttgttttact
     9061 tcaaaggaac gtgcaaaagg ctggatacca actaagtgat gtacatagat agctgatgcc
     9121 tttgactgat cagtactcga ttcagttgcc aaaataacca tatcaatctt agatcgatct
     9181 tcgtcggtta agatttgatc tgctgcagaa gcagctaaag taataatgtc ttcagtgatt
     9241 ggtgccacac taaaagactc aatgagtagc ccttgactaa attttgctgg atccacttgg
     9301 cgtgcaagcg ctaaatcttc caatttcaag acatattgac tggttgcaaa accaatctta
     9361 tcaattccaa ttgtcatatt tgtccttctt ttagttattt ttatagtctt acccattcta
     9421 tcacatttta ctgcaaaatt agactgataa agttatttgt tttatccttt
//
LOCUS       DATWVB010000049         9442 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.049, whole genome shotgun sequence.
ACCESSION   DATWVB010000049 DATWVB010000000
VERSION     DATWVB010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9442
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.049"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            88..1008
                     /gene="lmb"
                     /locus_tag="VCX65_001536"
     CDS             88..1008
                     /gene="lmb"
                     /locus_tag="VCX65_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HEP5053990.1"
                     /translation="MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            1021..3498
                     /locus_tag="VCX65_001537"
     CDS             1021..3498
                     /locus_tag="VCX65_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEP5053991.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGSATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYHFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPAPGRRKAPIPDVTP
                     NPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEED
                     GLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSDH
                     SKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHF
                     HYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGK
                     VGYMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSS
                     LPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPG
                     HEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKE
                     TFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQ
                     ADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIF
                     QPEGVQFYNKNGELVTYDIKTLQQINP"
     gene            3667..3867
                     /locus_tag="VCX65_001538"
     CDS             3667..3867
                     /locus_tag="VCX65_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEP5053992.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(3949..4575)
                     /locus_tag="VCX65_001539"
     CDS             complement(3949..4575)
                     /locus_tag="VCX65_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053993.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIIISHEFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(4559..5362)
                     /locus_tag="VCX65_001540"
     CDS             complement(4559..5362)
                     /locus_tag="VCX65_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5053994.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGNLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG"
     gene            complement(5374..6195)
                     /locus_tag="VCX65_001541"
     CDS             complement(5374..6195)
                     /locus_tag="VCX65_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053995.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNASLRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVSLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVVFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(6192..7169)
                     /locus_tag="VCX65_001542"
     CDS             complement(6192..7169)
                     /locus_tag="VCX65_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5053996.1"
                     /translation="MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRVKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV"
     gene            complement(7282..8910)
                     /locus_tag="VCX65_001543"
     CDS             complement(7282..8910)
                     /locus_tag="VCX65_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEP5053997.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQINIHLTEAHS
                     TFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELADKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINIGKQGVHSHGHDWSLLTNIAEWTWDESTK"
BASE COUNT         3106 a         1823 c         1871 g         2642 t
ORIGIN      
        1 aagatggtag ttgccattga caaagcattg ataaaggagt aaaattaact ggttaataac
       61 tggttaaatt ataattgagg aggtactatg aaaaaaggtt tttttctcat ggctatggtc
      121 gtgagtttag taatgatagc agggtgtgat aagtcagcaa accccaaaca gcctacgcaa
      181 ggcatgtcag ttgtaaccag cttttaccca atgtatgcga tgacaaaaga agtatctgga
      241 gacctcaatg atgtgaggat gatccaatca ggtgcaggca ttcattcctt tgaaccgtct
      301 gtaaatgatg tggcagctat ttatgacgcg gatttgtttg tttaccattc acatacctta
      361 gaagcttggg caagggatct agaccctaat ttaaaaaaat caaaggttga tgtgtttgaa
      421 gcgtcaaaac ctttgacact agatagagtc aaagggctag aagatatgga agtcacacaa
      481 ggcattgacc ctgcgacact ttatgaccca catacctgga cggatcccgt tttagctggt
      541 gaggaagctg ttaatatcgc taaagagcta ggacgtttgg atcctaaaca caaagacagt
      601 tacactaaaa aggctaaggc tttcaaaaaa gaagcagagc aactaactga agaatacact
      661 caaaaattta aaaaggtgcg ctcaaaaaca ttcgtgacgc agcacacggc attttcttat
      721 ctggctaaac gattcggctt gaaacaactt ggtatctcgg gtatttctcc agagcaagag
      781 ccctctcctc gccaattgaa agaaattcaa gactttgtca aagaatacaa cgtcaagact
      841 atttttgcag aagacaatgt caatcccaaa attgctcatg ctattgcgaa atcaacagga
      901 gctaaagtaa agacattaag tccacttgaa gctgctccaa gcggaaacaa gacatatcta
      961 gaaaatctta gagcaaattt ggaagtgctc tatcaacagt tgaagtaaag gagattatta
     1021 gtgaagaaaa catatggtta tatcggctca gttgctgcca ttttactagc tactcatatt
     1081 ggaagttacc aacttggtaa gcatcatatg ggttcagcaa caaaggacaa tcaaattgcc
     1141 tatattgatg atagcaaagg taaggcaaaa gcccctaaaa caaacaaaac gatggatcaa
     1201 atcagtgctg aagaaggcat ctctgctgaa cagatcgtgg tcaaaattac tgaccaaggc
     1261 tatgtgacct cacacggtga ccattatcat ttttacaatg ggaaagttcc ttatgatgcg
     1321 attattagtg aagagttgtt gatgacggat cctaattacc attttaaaca atcagacgtt
     1381 atcaatgaaa tcttagacgg ttacgttatt aaagtcaatg gcaactatta tgtttacctc
     1441 aagccaggta gtaagcgcaa aaacattcga accaaacaac aaattgctga gcaagtagcc
     1501 aaaggaacta aagaagctaa agaaaaaggt ttagctcaag tggcccatct cagtaaagaa
     1561 gaagttgcgg cagtcaatga agcaaaaaga caaggacgct atactacaga cgatggctat
     1621 atttttagtc cgacagatat cattgatgat ttaggagatg cttatttagt acctcatggt
     1681 aatcactatc attatattcc taaaaaggat ttgtctccaa gtgagctagc tgctgcacaa
     1741 gcctactgga gtcaaaaaca aggtcgaggt gctagaccgt ctgattaccg cccgacacca
     1801 gccccagccc caggtcgtag gaaagcccca attcctgatg tgacgcctaa ccctggacaa
     1861 ggtcatcagc cagataacgg tggctatcat ccagcgcctc ctaggccaaa tgatgcgtca
     1921 caaaacaaac accaaagaga tgagtttaaa ggaaaaacct ttaaggaact tttagatcaa
     1981 ctacaccgtc ttgatttgaa ataccgtcat gtggaagaag atgggttgat ttttgaaccg
     2041 actcaagtga tcaaatcaaa cgcttttggg tatgtggtgc ctcatggaga tcattatcat
     2101 attatcccaa gaagtcagtt atcacctctt gaaatggaat tagcagatcg gtacttagcc
     2161 ggccaaactg aggacaatga ctcaggttca gatcactcaa aaccatcaga taaagaagtg
     2221 acacatacct ttcttggtca tcgcatcaaa gcttacggaa aaggcttaga tggtaaacca
     2281 tatgatacga gtgatgctta tgtttttagt aaagaatcca ttcattcagt ggataaatca
     2341 ggagttacag ctaaacacgg agatcatttc cactatatag gatttggaga acttgaacaa
     2401 tatgagttgg atgaggtcgc taactgggtg aaagcaaaag gtcaagctga tgagcttgct
     2461 gctgctttgg atcaggaaca aggcaaagaa aaaccactct ttgacactaa aaaagtgagt
     2521 cgcaaagtaa caaaagatgg taaagtgggc tatatgatgc caaaagatgg caaggactat
     2581 ttctatgctc gtgatcaact tgatttgact cagattgcct ttgccgaaca agaactaatg
     2641 cttaaagata agaagcatta ccgttatgac attgttgaca caggtattga gccacgactt
     2701 gctgtagatg tgtcaagtct gccgatgcat gctggtaatg ctacttacga tactggaagt
     2761 tcgtttgtta tccctcatat tgatcatatc catgtcgttc cgtattcatg gttgacgcgc
     2821 gatcagattg caacaatcaa gtatgtgatg caacaccccg aagttcgtcc ggatgtatgg
     2881 tctaagccag ggcatgaaga gtcaggttcg gtcattccaa atgttacgcc tcttgataaa
     2941 cgtgctggta tgccaaactg gcaaattatc cattctgctg aagaagttca aaaagcccta
     3001 gcagaaggtc gttttgcaac accagacggc tatattttcg atccacgaga tgttttggcc
     3061 aaagaaactt ttgtatggaa agatggctcc tttagcatcc caagagcaga tggcagttca
     3121 ttgagaacca ttaataaatc tgatctatcc caagctgagt ggcaacaagc tcaagagtta
     3181 ttggcaaaga aaaatgctgg tgatgctact gatacggata aacccaaaga aaagcaacag
     3241 gcagataaga gcaatgaaaa ccaacagcca agtgaagcca gtaaagaaga agaaaaagaa
     3301 tcagatgact ttatagacag tttaccagac tatggtctag atagagcaac cctagaagat
     3361 catatcaatc aattagcaca aaaagctaat attgatccta agtatctcat tttccaacca
     3421 gaaggtgtcc aattttataa taaaaatggt gaattggtaa cttatgatat caagacactt
     3481 caacaaataa acccttaacc aaaagaagat ctcattgtta aagcactgct ttgtcaaagc
     3541 aagttaccgt gattttgaag tcattttatg taacgagtag tgataaaagt tggataatag
     3601 cggttttctt ttgcaaagaa atggtatcca tgttagaata ataaaaaaaa gaggaggatt
     3661 ctaatcatgt cagaagaaaa attaaaatca aaaattgagc aagcatctgg tggcctaaaa
     3721 gaaggtgctg gtaagttgac aggtgataaa gagctagaag caaaaggatt tgttgaaaaa
     3781 acaattgcta aaggcaaaga acttgcagac gatgcaaaag aagcggttga aggtgctgta
     3841 gatgccgtta aggaaaaatt aaaataatta aaaaaaccag ctgtaagctg gtttttttaa
     3901 tggtgtgatt ttgttaggaa aagactcaat aggtaataac cgtaggtgtt aggtatgctt
     3961 gaacagttga gtacgattct cttcaatcat atagcacgcg tcacaaagtt tttctaacat
     4021 atcaaactca tgactaataa tgatgagacc taaatttcta tcctttacaa tctccaacag
     4081 gcttttccat acactagctt gtgtaatgct atccaacata gtagtcattt catctgcaat
     4141 aaggtatttc gtctctggat gtaatgaacg cacaatcgaa aagcgttgca attcccctcc
     4201 cgagagttca ctagggcgac gctttagcca tttttcttga atgccaaaag catctcgcaa
     4261 atcttgactt ggatagtagg cttcttccaa actttttttc ataggccata aaggattcat
     4321 ggtttgttca ggatgttgtt ggataagttg tacaggtcta aatgctttgt taggcaaatg
     4381 actgccatca actaatactt caccagattt aggctgcaaa aaaccggcaa gcactctgga
     4441 taaacttgtt tttccacacc cactttgtcc aaatatccct aagatttgac caggtgctac
     4501 ctctaaatca atctccttaa aaagccattg atctttttta tgataaaagc caagcttttt
     4561 agcctctaag gtcatgagta actcctttca aaaagtcttg ctgagggagt gtgcgccata
     4621 aacgtctcgc aaattctgtt tgtaattgct ccccacctcc gctaaaaaag ctagctgggg
     4681 ctgtttcaat agcttttccc tctttaaaaa tagttatacg atccgcaatt tgactagctg
     4741 ctacaatatc atgagtgata aatatgacgc ttattccttt atctgcaaag gagcgtagtt
     4801 gatctaaaac catttgcaga gcatctggat gtaatccagg ggtgggctca tccgcaataa
     4861 tcaaagaaac cgtatcacta atacacgttg taaacaaaac acgtcggagc attccgccag
     4921 aaagttggaa aggatacaag ttaccatcac tttcttttaa accaaactgt tgaaacaatc
     4981 cttcttgagt agccttagca ttttctgaga tacccaagcg cacctgatgc ttgactttca
     5041 tagatggatc taaataatta acggattgtg gaatcaacgt catttctttt cctcgcaact
     5101 gtttgatgcg tttagaagtt agtgattgac cacgataaat catatctcct gttacagctg
     5161 catttttagg aagaatatcc ataatagcat gtgctaataa actcttgcct gaaccactag
     5221 cacctataat agctaataac tcaccttttt taacttctaa attcagcgct tggatcggtg
     5281 tggattgaaa tggttttaaa aatcttccgt attgagtgaa ggtgatggag aggtctttaa
     5341 tgcttaataa tgtttctgtc atatctctac ctcctaaaaa tgatccgttt gagggtaaaa
     5401 gagtttcttt aaagattctc cgatagtatc aaaggcattg acaactaaaa taagataaag
     5461 gcctggaaaa accaccaacc accaattgcc aagagagata tgcttagctg cttctgacag
     5521 aatgatacca accgaaggtt gttcggcaga aaggccaaat cctaagaaag tcatggatgc
     5581 ttcatgcaag atgacgtgcg gaaataagag gataaaccca atgaaaattt gagaagcaat
     5641 caaaggcagg atatgatgcc tcacaatata ataaggcgtt tttcccatgc ttttagagag
     5701 ctggacaaag gctttattct ttagatcata gacttcattg cggataagcc ttgctagaga
     5761 gggccaatgg gtaacagccg ttgcaatgat aaccccttga gcccctttac caacaacaaa
     5821 agaaatgaga atcataaaaa tcaaatgagg cataccaata aacaaatcaa ccaaccaggc
     5881 tattatttta tcaataaggc tatttcctag acctgcaagc actccaaaaa cggtcgcaag
     5941 agagactccc ataagggcac ctaataagcc gacttgtaaa gagaaataaa gccctttaat
     6001 cgttctgacg aacatatccc tacctaaacc atctgtccca aaaagatggt ttaaggaagg
     6061 agcgaggttg cgtaaagatg cattggtttc caaaggcgtc ctatagaaat aaaggtttaa
     6121 ggctagaata ctaagaatga gagaaatggc gatacctagt tgccataaaa ccatcgttcg
     6181 acgtttcaat atcatacttt tctccttaac tgtggattga tgatgctatt taaaatatcc
     6241 gcaataagat tgcccgcaaa aacaaataat gtccctatca tcacgatagc tagaaggagc
     6301 ggtgtatcac ttttaagtcc tgcttcagtg agggtagacc ctaagccagg atatgagaaa
     6361 acttgctcag caagaacaga tcctccaaac aattctccaa aataggaaaa atgcagtgta
     6421 atagctggta cgatagcatt tctaaggcaa tgatgtttaa aaatttgcca ctgtgtttcc
     6481 ccacgcgctc tggcaaataa gacatattca ctagaaagca ccgacatcat tttagttctc
     6541 gtatgaaggg tgacattggc aatgcctaga atacttaacg tgaaaacagg taacataagg
     6601 tgcttaaccc gatcagctaa cgtaatatct tgactcaaag tgcctatcgg ggaagaaata
     6661 ccaatcggga accaccccag ctggacagaa aagattaata aaaaaatgag gccaatccaa
     6721 aacgttggta ctgatatctg aaggtaagaa aaccacctga caactcgatc aagtaatttc
     6781 ccttgatgga aagcggataa cgttcctaag ataaatccaa taagacccga taagatccaa
     6841 gagagtccca taagtatgaa agaagcacct gcccgtgatc taataatatc actaacaggt
     6901 tgccgataaa cgagcgaggt ccctaaatgt ccctgtatca catttttcaa ccaaataaaa
     6961 tactggacta gagctggctt atccaagcca tagtggtgag caatcgcttt gtactgagca
     7021 ggggttagtg atgtgtcata attgacactt gccatgactg gatctactgg agattgtttt
     7081 aacaaaacga aggtcaaaac agatacccca aaaataagcg tgacacatct gatgattttc
     7141 cagatgataa taatggtagt acgtttcaca atgaaatctc cttaatcgat aagaaaagga
     7201 gccgaggaaa cgatcagcac agttttgtgt atcttgtttt ctcagactcc aaacttaaaa
     7261 tcgctgtatt aactaaacgc gttacttagt tgattcatcc caagtccact cggcaatgtt
     7321 agtcaataat gaccaatcat gaccatgact gtggacgccc tgtttaccta tattgatacg
     7381 tttatcacca atataagtat ggttaaggct caccaaccat acatttggca aatctccaag
     7441 agtagaagca cctgttttgc catcccactg cgctaacttc caatattcgt tagctttgtc
     7501 aaggtcagaa gatgtcattg ctttgtcaag gtacttagtc acggtaggat tgttataaaa
     7561 cgtaatattg gtccaacctt tacctgctag gcttggatga tgtgattcat aaaattgctg
     7621 cgcgtgatga cgtcctccgg cataaagtaa ggctgagtca tgtgacttcg ttgccatttc
     7681 atcccagtta ctagctttga gtttaatagt aatccctagg gctttggctt gctctgctac
     7741 ttcaacggct aagttcgctc gcaattgatc attagtaggg tagtacagat caaacgctgc
     7801 atcaaggtca ccttttttac ggctaccgtc tgcttgttct ttccatccag cttttgtcaa
     7861 caattgctta gctttagcta ctttattatc tttaatggct gtttttggat tccaaaatgg
     7921 tgttttatca ataattgaat aagctggttt accataacca tttaaaaccg tatcgagaac
     7981 tttttgccta tttaaaccaa tagtcaaggc ttttcggatt gctggatcac tagtgacatc
     8041 atttcctaca ggataaccat caggagaatc agtgatgacg ccttttttca cataaggtaa
     8101 tgataagccg cgcacatcat ttgatggaat atcaaggagg cgggtgcctt tgactttttt
     8161 atcagcaagt tctggcgttg cgtagatcat atcaacatca ccagattcta aagctgctag
     8221 tgctgtgttt tcatcaagta agacccaagt ccatttttta aagtatggtt ttttcccatg
     8281 ccaataaggg ttacgaacaa aaatagcttg ttctccagcc ttatattctt ttaccatgta
     8341 aggtcctgaa ccgataggat tgctcttata cttatcattg taatgttttt tagggacgat
     8401 tgggatttca gtcaactgtg ctgtaaatgt cgaatgcgcc tcagtcaaat ggatattgat
     8461 ctgatttttc ccaactactt caacgttctt gatgaaggtt agatcccaag cctttccatc
     8521 tgctttcaac atatcataag taaacttaac atcatcagca gtaacaggct caccatttga
     8581 gaatttaaaa tcatcatgca agtcaaacga ccaagtcagc ccatcttcag agagatggta
     8641 tgttttagca agctctcctt ttatatctag ttcaggagaa cgtttcaata gagtgctatg
     8701 agtgatattc ccttcattgt ggactccata acggtccttt ggatcgaatt catgagggag
     8761 ctttgccccc atagaaacga caagttcgtc ttttggacgt tgtttgcgct gacgttcttt
     8821 tgtttgaggc ttttgttgtt gacatgcaac taaaataagc ccagtcaaaa ataacgtgat
     8881 aatagagaag tattttaggt attttgacac aatcaaatct ccttatttct aattaataaa
     8941 taataatagt aacgactcca tctcattata gcaataaaca aataggaggg caattgttta
     9001 actggttaat tagaattttt gttattttta ggaagatact caggactttt ttataagttg
     9061 atgtattaac aaaagataaa gaggtttcat gacttatttt agattaaaaa aagaattaaa
     9121 ctgatcacta agaaataaag gaattgtagt ttacgaaggg aatcaaaaac ttcagatagc
     9181 cattaataca ggtaaaaata acagtgaaaa aagtcttttt tgatactttt cttgaggtgg
     9241 ttcgggcggc agcgactttc tccacaggaa aaaacatctg ttttggtctt ggcttacttc
     9301 gttcgcagaa ataggaaatc gggtatcaca ttagcagagt agttcatgtt ttttgagcat
     9361 cacactggat ctgtctacgt tctaaaagct ttcttcattt ttgtatcata ccccctacaa
     9421 gtagaaaaag tataacaaag aa
//
LOCUS       DATWVB010000050         9024 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.050, whole genome shotgun sequence.
ACCESSION   DATWVB010000050 DATWVB010000000
VERSION     DATWVB010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9024
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.050"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            250..1857
                     /locus_tag="VCX65_001544"
     CDS             250..1857
                     /locus_tag="VCX65_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP5053998.1"
                     /translation="MHVSKLFTSQQWRELKLISYLTENSNAIGVKDKELSKALNISML
                     TLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFR
                     DFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLK
                     YFSEAYKISEWPFGDILNLKNCERLLSLLIKEVDVKVHFTLFQHLKILSGVNLIRYYK
                     GYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLE
                     IGCAFEIINQDPISGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDI
                     TANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVSKELINQLTYCFFIT
                     WENSFLKVNQKEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIEK
                     QYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKNLEAPSPS
                     KSHSDKEVQKPEKPDNSVKQATSATSS"
     gene            2047..3096
                     /locus_tag="VCX65_001545"
     CDS             2047..3096
                     /locus_tag="VCX65_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEP5053999.1"
                     /translation="MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKAETE
                     HVDVVLSAKEANKVFEERKALEKQARDLGDTINHMSQTISEQSRKIAALKSEAELKNQ
                     QALEALNNKNEQIAKLTNENAQLKEAIEGYVQTIQNASREIAAKQQELAAAKSQLEAK
                     NAEIEALKQQDASKTEEIAKLQSEAATLENLLGSAKRELTDLQAKLDTANTEKEKLQS
                     QAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAKQAEELAKLKADK
                     ASGAQKPDTKPGNKEVPTRPSQTRTNTNKAPMAQTKRQLPSTGEETTNPFFTAAAATV
                     IASAGVLALKRKEEN"
     gene            3321..4397
                     /locus_tag="VCX65_001546"
     CDS             3321..4397
                     /locus_tag="VCX65_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407885.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEP5054000.1"
                     /translation="MARKDTNKQYSLRKLKTGTASVAVAVAVLGAGFANQTEVKAAES
                     PKSTETSANGADKLADAYNTLLTEHEKLRDEYYTLIDAKEEEPRYKALRGENQDLREK
                     EGKYQDKIKKLEEKEKNLEKKSEDVERHYLKKLDQEHKEQEERQKNLEELERQSQREI
                     DKRYQEQLQKQQQLETEKQISEASRKSLSRDLEASRAAKKDLEAEHQKLKEEKQISDA
                     SRQGLSRDLEASREAKKKVEADLAEANSKLQALEKLNKELEEGKKLSEKEKAELQARL
                     EAEAKALKEQLAKQAEELAKLKGNQTPNAKVAPQANRSRSAMTQQKRTLPSTGEAANP
                     FFTAAAATVMVSAGMLALKRKEEN"
     gene            4608..5540
                     /locus_tag="VCX65_001547"
                     /pseudo
     CDS             4608..5540
                     /locus_tag="VCX65_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561044.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            5875..>9024
                     /gene="scpA/B"
                     /locus_tag="VCX65_001548"
     CDS             5875..>9024
                     /gene="scpA/B"
                     /locus_tag="VCX65_001548"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HEP5054001.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VEPPQPTAVSEEAPSSSKETNPPQIPDDAEETVADKANDPAPQAPAKTADTPATSKAT
                     IRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKA
                     KKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEG
                     AMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDET
                     KKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSP
                     DKQLTETATVKTDDHQDKEMPVLSTNRFEPNKAYDYAYANRGTKEDDFKDVEGKIALI
                     ERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDN
                     PQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAK
                     LSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYF
                     SPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELY
                     YQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMK
                     NGYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSD
                     AKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGT
                     FAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGN
                     VVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPIS
                     SGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPIYRERIAYTYMDE
                     DLPTTEYISPNEDGTFTLPEEAETMEGGTVPLKMSDFTYVVEDMAGNITYTPVTKLLE
                     GHSNKPEQDGSDQAPDKKPE"
BASE COUNT         3357 a         1734 c         1776 g         2157 t
ORIGIN      
        1 tgaatgacat aaatgtcgct aaaaaaatag atagaagagt ctaaaatttc agttttaggt
       61 cacgttttat gaatggaaat cagaatgatg accttaagtt gtgatttgcg cgtcattgac
      121 cgctttcttc gttttaatga aagaatttga aagatatttt atggtatact tttccttaat
      181 atggttcata cggacttgat aaatctattt acaaaaataa taaaaaatta agataaggac
      241 atgaagttaa tgcatgtaag taaattgttt actagccaac aatggagaga attgaaactg
      301 atctcatatt taacagaaaa ctccaatgct atcggagtta aagataagga gcttagcaag
      361 gctctcaata tttccatgtt aacattacag tcatgcctca ctaatatgca gtttatgaaa
      421 gaagtaggtg gaattaccta caaagacggc tatattaaca tttggtatca ccagtgttgt
      481 gggctacaag aggtctatca aaaagctctt cgagaatcgc cttctttgaa attactggag
      541 cttttgtttt tcagagactt tagttcctta gaagagttag ctgaagagct gtttgtcagc
      601 ttatctaccc tcaaacgcct catcaaaaaa accaacactt acttgtctca tacctttgct
      661 attagtatcg tgacaagtcc agtgcaggtg tcaggagatg agaggcaaat tcgcctgttt
      721 tacctcaagt atttttcaga agcctataaa atctcagaat ggccatttgg ggacatttta
      781 aacctgaaaa actgtgaacg cctattgagc ttattgatca aagaagtaga tgtcaaagtt
      841 cattttacgc tatttcagca cttaaaaatc ttaagtggcg tcaacttgat ccgttactac
      901 aaggggtatt cttgcagtta taacaataaa aaaaccagtc accgtttttc tcaacttatc
      961 caacattcct cagaaatcca ggatctttct cgcttgttct acctcaaatt tgggttacat
     1021 ctcgacgagt ataccatagc tgaaatgttt tctaaccatc ttaacgacaa gctagaaatt
     1081 ggctgtgctt ttgagattat caatcaagac ccaatatcag gaggcagaca agtaaccaac
     1141 tggatccatc tattagatga gatggaaatc aagctcaatc tcagcatcac caataaatac
     1201 gaagttgccg taaccctcca taacgcttcg gtgttaaacg aagaagacat tacagccaat
     1261 tatttgctgt ttgattataa aaagagttac ctgaactttt accaaaaaga acaccctcgt
     1321 atctatgagg cctttgtgac aagtgtcgag aagctgatgc aggcagataa tgctcaagtt
     1381 agcaaagaat tgatcaatca gctcacttat tgtttcttta ttacctggga aaatagtttc
     1441 ttaaaagtaa atcaaaaaga aaaagtacga ctcctagtga tagagagaag ttacaatagt
     1501 gtcggtaatt ttttgaaaaa gtacatcggt gagtttttca gcattactaa ttttgatgag
     1561 ttagattgtc tgacaattga tctagtagag attgaaaaac agtacgatgt tatcgtgaca
     1621 gatgttatgg tgggtaaaag cgaagagtta gagattttct ttttctacaa gatgatccca
     1681 gaagctatta ttgatagatt aaacgaattt ttgaacgtta gtttcacaga taacaatgtt
     1741 atggtcaaaa acctcgaagc cccttctcct tcaaaatctc atagcgacaa agaggtacaa
     1801 aagccagaaa agccagacaa ttctgttaaa caagcaacat cagcaacatc atcataggat
     1861 ttcagacgtc atggtaagaa aaaaagaatc atttacagcc catagaggta aggtcaaaag
     1921 ctgaaaacag ctcaaaaaaa ctgaccttta ccttttggct ttttttattt agaataattt
     1981 tattggagag atgcttaatc taatttaagc acaattctta gaaagttaag aaataaggag
     2041 taaacaatgt ctaaaagaaa tccaaacaaa cactactcac tgagaaagtt aaaaacaggt
     2101 actgcatcag tagcagtagc tttgacagtt ttggggactg gattagcaaa cacaactgat
     2161 gtaaaggctg agactgagca tgttgatgtt gtgctttcag caaaagaagc taacaaagta
     2221 ttcgaagagc gcaaagcctt ggaaaaacaa gcgcgtgatt tgggtgacac tattaatcac
     2281 atgtcacaaa ccattagtga gcaaagccgc aagattgcag cattaaagtc tgaagcagaa
     2341 cttaaaaacc aacaagctct tgaagcttta aataataaaa atgagcagat tgctaaatta
     2401 accaacgaaa acgcacagtt aaaagaagcc attgaaggtt atgtgcaaac tatccaaaac
     2461 gctagccgtg aaatcgcagc aaaacaacaa gaacttgcag ctgcaaaaag ccagttagag
     2521 gcaaaaaatg ctgagattga ggcattgaaa caacaagatg cctctaagac tgaggaaatt
     2581 gctaaattgc aatcagaagc agcaacttta gaaaacctcc taggttcagc taagcgtgaa
     2641 ttgactgatc tgcaagctaa gctagataca gctaacactg aaaaagaaaa gctccaatca
     2701 caagcagcag ccctagaaaa acaactagaa gcaactaaaa aagagttagc tgatttacag
     2761 gctaaattag cagcaaccaa ccaagaaaaa gaaaagttag aagctgaagc aaaagctctt
     2821 aaagagcaat tagcaaaaca agctgaagag cttgctaagc taaaagcaga taaagcttca
     2881 ggagctcaaa aaccagatac taaacctggc aataaagagg ttccaacaag accgtcacaa
     2941 acaagaacaa acactaataa agctcctatg gcgcaaacaa agagacaatt accgtcaaca
     3001 ggcgaagaaa caaccaaccc attcttcact gcagcagctg caacagtgat cgcatctgca
     3061 ggcgtacttg ccctaaaacg caaagaagaa aactaagccc aatccacact atcttttcta
     3121 gcccaagaaa aaaacaaaaa aagaggaaga ccattcctct ttttttgaac ggttaaacag
     3181 caaaaaggtc aaaaaggtac taaagtctca aaaacctggt ctttaccttt taccgcttat
     3241 tctttagaat agaattatta gagagaagtc ttagaaaaat gaggctaatt ccctaaagat
     3301 gaaaaaataa ggagcaaata atggctagaa aagatacgaa taaacagtat tcgcttagaa
     3361 aattaaaaac aggtacagca tccgtagcgg tcgctgtggc tgttttagga gcaggctttg
     3421 caaaccaaac agaagttaag gctgcggagt ctccaaaaag tactgagact tctgctaatg
     3481 gagctgataa attagctgat gcatacaaca cattgcttac tgaacatgag aaactcagag
     3541 atgagtatta tacattaatt gatgctaaag aagaagaacc taggtataaa gcattgagag
     3601 gcgaaaatca agatcttcgg gaaaaagaag gaaaatacca ggataaaata aaaaaattag
     3661 aagaaaaaga gaaaaattta gaaaaaaaat cagaagatgt agaacgtcac tatcttaaaa
     3721 aactagatca agaacataaa gaacaagaag aacgtcaaaa aaatctagaa gaactcgaac
     3781 gtcaaagtca acgagaaata gacaagcgtt atcaagaaca actccaaaaa caacaacaat
     3841 tagaaacaga aaagcaaatc tcagaagcta gtcgtaagag cttaagccgt gaccttgaag
     3901 cgtctcgtgc agctaaaaaa gaccttgaag ctgagcacca aaaactcaaa gaggaaaaac
     3961 aaatctcaga cgcaagccgt caaggcctaa gccgtgacct tgaagcgtct cgcgaagcta
     4021 agaaaaaagt agaagcagac ttagcagaag caaatagcaa acttcaagcc cttgaaaaac
     4081 taaacaaaga gcttgaagaa ggtaagaaat tatcagaaaa agaaaaagct gagttacaag
     4141 caagactaga agctgaagca aaagctctta aagagcaatt ggctaaacaa gctgaagaac
     4201 ttgctaaact aaaaggcaac caaacaccaa acgctaaagt agccccacaa gctaaccgtt
     4261 ctagatcagc aatgacgcaa caaaagagaa cgttaccgtc aacaggcgaa gcagctaacc
     4321 cattctttac agcagcagct gcaacagtaa tggtatctgc aggtatgctt gctctaaaac
     4381 gcaaagaaga aaactaagct attagactga tgctaaagtt aagagagaat caaatgattc
     4441 tctctttttg agtggctaag taactaacaa tctcaattag accaaaaaat gggaatggtt
     4501 caaaaagctg gcctttactc cttttgatta accatatata agtaaaaaca ttaggaaaat
     4561 aatagtaata ttaagtttgt ttcctcaata aaatcaagga gtagataatg gctagacaac
     4621 aaaccaagaa aaattattca ctacggaaac taaaaaccgg tacggcttga gtagccgttg
     4681 ctttgaccgt tttgggtgca ggttttgcaa accaaacgga agtaagagct gaaggggtaa
     4741 acccgactac gaacttgcca gagaaggcta aatatgccgc attgaaagat gagaatactg
     4801 gtttacgtgg tgatcagaaa aaattagtaa aaaaacttga agaagaacaa gagaagagca
     4861 aaaatctaga aaagcaaaaa caggagttag aaaaccaagc ccttaacttt caagacgtaa
     4921 ttgaaactca ggaaaaagaa gatctcaaaa caactttagc taagactact aaagaaaatg
     4981 agatttcaga agctagccgt aaagggttaa gccgagactt agaagcttct cgtgcagcta
     5041 aaaaagagct agaagctaag caccaaaaat tagcagaaga acatcaagtt tcagagacta
     5101 gccgtaaggg tctaagccgt gaccttgaag catcacgtga agctaataag aaggttacat
     5161 ctgagttaac acaagcaaaa gctcaactct cagcgcttga agaaagtaag aaattatcag
     5221 aaaaagaaaa agctgagtta caagcaaaac tagatgcaca aggaaaagcc ctcaaagaac
     5281 aattagcaaa acaaactgaa gagcttgcaa aactaagagc tgaaaaagcg gcaggttcaa
     5341 aaacacctgc taccaaacca gctaataaag aaagatcagg tagagctgct caaacagcta
     5401 caagacctag ccaaaataaa ggaatgagat cacaattacc gtcaacaggc gaagcagcta
     5461 acccattctt tacagcagca gctgcaacag tgatggtatc tgcaggtatg cttgctctaa
     5521 aacgcaaaga agaaaactaa gcctttagaa cttggttttt gtaacggtgc aatagacaaa
     5581 agtaagcaag gccaaaaact gagaaagtcc taaaaagctg gcctttaccc ctcaaaatta
     5641 atgttttata ataaagatgt tagtaatata attgataaat gagatacatt taatcattat
     5701 ggcaaaagca agaaaaatag ctgtatcata tgcaaataac ccctgtttgc tctttaaaaa
     5761 agacgttatc cttatttctc cacgcacaga tggacagcta ggagagaatc gtttgattct
     5821 ctcttttctt aatggtcata aagacaaagt ctctcatcat gaaaggacga cacattgcgt
     5881 aaaaaacaaa aattaccatt tgataaactt gccattgcgc tcatgtctac gagcatcttg
     5941 ctcaatgcac aatcagacat taaagcaaat actgtgacag aagacactcc tgctaccgaa
     6001 caagccgtag aacccccaca accaacagcg gtttctgagg aagcaccatc atcatcaaag
     6061 gaaactaacc ctccacaaat tcctgatgac gcagaagaaa cagtagcaga taaggctaat
     6121 gatccagccc ctcaagctcc tgctaaaact gctgatacac cagcaacctc aaaagcgact
     6181 attagggatt tgaacgaccc ttctcaggtc aaaaccctgc aggaaaaagc aggcaaggga
     6241 gctgggactg ttgttgcagt gattgatgct ggttttgata aaaatcatga agcgtggcgt
     6301 ttaacagaca aaaccaaagc acgttaccaa tcaaaagaag atcttgaaaa agctaaaaaa
     6361 gagcacggta ttacctacgg cgagtgggtc aatgataagg ttgcttatta ccacgactat
     6421 agcaaagatg gtaaaaccgc tgtcgatcaa gagcacggca cacacgtgtc agggatcttg
     6481 tcagggaatg ctccatctga aacgaaagaa ccttaccgcc tagaaggtgc gatgcctgag
     6541 gctcaattgc ttttgatgcg tgtcgaaatt gtaaatggac tagcagacta tgctcgtaac
     6601 tacgctcaag ctatcagaga tgctgtcaac ttgggagcta aggtgattaa tatgagcttt
     6661 ggtaatgctg cactagctta cgccaacctt ccagacgaaa ccaaaaaagc ttttgattat
     6721 gccaaatcaa aaggtgttag cattgtgacc tcagctggta atgatagtag ttttgggggc
     6781 aaaacccgtc tacctctagc agatcatcct gattatgggg tggttgggac acctgcagcg
     6841 gcagattcaa cattgacagt tgcttcttac agcccagata aacagctcac tgaaactgct
     6901 acggtcaaaa cagacgatca tcaagataaa gaaatgcctg ttctttcaac aaaccgtttt
     6961 gagccaaaca aggcttacga ctatgcttat gctaatcgtg gtacgaaaga ggatgatttt
     7021 aaggatgtcg aaggtaagat tgcccttatt gaacgtggcg atattgattt caaagataag
     7081 attgcaaacg ctaaaaaagc tggtgctgta ggggtcttga tctatgacaa tcaggacaag
     7141 ggcttcccga ttgaattgcc aaatgttgat cagatgcctg cggcctttat cagtcgaaaa
     7201 gacggtctct tattaaaaga caatccccaa aaaaccatca ccttcaatgc gacacctaag
     7261 gtattgccaa cagcaagtgg caccaaacta agccgcttct caagctgggg tctgacagct
     7321 gacggcaata ttaagccaga tattgcagca cccggccaag atattttgtc gtcagtggct
     7381 aacaacaagt atgccaaact ttctggaact agtatgtctg cgccattggt agcgggtatc
     7441 atgggactat tgcaaaagca atatgagaca cagtatcctg atatgacacc atcagagcgt
     7501 cttgatttag ctaaaaaagt attgatgagc tcagcaactg ccttatatga tgaagatgaa
     7561 aaagcttatt tttctcctcg ccaacaagga gcaggagcag tcgatgctaa aaaagcttca
     7621 gcagcaacga tgtatgtgac agataaggat aatacctcaa gcaaggttca cctgaacaat
     7681 gtttctgata aatttgaagt aacagtaaca gttcacaaca aatctgataa acctcaagag
     7741 ttgtattacc aagcaactgt tcaaacagat aaagtagatg gaaaacactt tgccttggct
     7801 cctaaagcat tgtatgagac atcatggcaa aaaatcacaa ttccagccaa tagcagcaaa
     7861 caagtcaccg ttccaatcga tgctagtcga tttagcaagg acttgcttgc ccaaatgaaa
     7921 aatggctatt tcttagaagg ttttgttcgt ttcaaacaag atcctaaaaa agaagagctt
     7981 atgagcattc catatattgg tttccgaggt gattttggca atctgtcagc cttagaaaaa
     8041 ccaatctatg atagcaaaga cggtagcagc tactatcatg aagcaaatag tgatgccaaa
     8101 gaccaattag atggtgatgg attacagttt tacgctctga aaaacaactt tacagcactt
     8161 accacagagt ctaacccatg gacgattatt aaagctgtca aagaaggggt tgaaaacata
     8221 gaggatatcg aatcttcaga gatcacagaa accatttttg caggtacttt tgcaaaacaa
     8281 gacgatgata gccactacta tatccaccgt cacgctaatg gcaagccata tgctgcgatc
     8341 tctccaaatg gggacggtaa cagagattat gtccaattcc aaggtacttt cttgcgtaat
     8401 gctaaaaacc ttgtggctga agtcttggac aaagaaggaa atgttgtttg gacaagtgag
     8461 gtaaccgagc aagttgttaa aaactacaac aatgacttgg caagcacact tggttcaacc
     8521 cgttttgaaa aaacgcgttg ggacggtaaa gataaagacg gcaaagttgt tgctaacgga
     8581 acctacacct atcgtgttcg ctacactccg attagctcag gtgcaaaaga acaacacact
     8641 gattttgatg tgattgtaga caatacgaca cctgaagtcg caacatcggc aacattctca
     8701 acagaagatc gtcgtttgac acttgcatct aaaccaaaaa ccagccaacc gatttaccgt
     8761 gagcgtattg cttacactta tatggatgag gatctgccaa caacagagta tatttctcca
     8821 aatgaagatg gtacctttac tcttcctgaa gaggctgaaa caatggaagg cggtactgtt
     8881 ccattgaaaa tgtcagactt tacttatgtt gttgaagata tggctggtaa catcacttat
     8941 acaccagtga ctaagctatt ggagggtcac tctaataagc cagaacaaga tggttcagat
     9001 caagcaccag acaaaaaacc agaa
//
LOCUS       DATWVB010000051         8869 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.051, whole genome shotgun sequence.
ACCESSION   DATWVB010000051 DATWVB010000000
VERSION     DATWVB010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8869
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.051"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            42..1238
                     /locus_tag="VCX65_001549"
     CDS             42..1238
                     /locus_tag="VCX65_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEP5054002.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            1304..2011
                     /locus_tag="VCX65_001550"
     CDS             1304..2011
                     /locus_tag="VCX65_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEP5054003.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQITGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEILR
                     LLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADILLPD"
     gene            2074..3129
                     /gene="prsA"
                     /locus_tag="VCX65_001551"
     CDS             2074..3129
                     /gene="prsA"
                     /locus_tag="VCX65_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEP5054004.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            3516..6134
                     /gene="alaS"
                     /locus_tag="VCX65_001552"
     CDS             3516..6134
                     /gene="alaS"
                     /locus_tag="VCX65_001552"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEP5054005.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPDWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYNPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAETV"
     gene            6495..6710
                     /locus_tag="VCX65_001553"
     CDS             6495..6710
                     /locus_tag="VCX65_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5054006.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            6707..7468
                     /locus_tag="VCX65_001554"
     CDS             6707..7468
                     /locus_tag="VCX65_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEP5054007.1"
                     /translation="MKKKKNSFLRLLKMLLLSSLAGGIIGGMVGAFLGYHGERLDQLT
                     FLKDDVINLIILLNRLVVVTGLTLSFVFLTQLKKETAVYNTIEEDDYSENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            7487..8182
                     /locus_tag="VCX65_001555"
     CDS             7487..8182
                     /locus_tag="VCX65_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEP5054008.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIAGTLVNQL
                     WSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
     gene            complement(8276..8803)
                     /locus_tag="VCX65_001556"
                     /pseudo
     CDS             complement(8276..8803)
                     /locus_tag="VCX65_001556"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2767 a         1524 c         1835 g         2743 t
ORIGIN      
        1 tttaaaaaat aaacgttcgt ataataaaaa aggagttttt tatggaaaaa acaaaacgtt
       61 atatcattgc aacagcaggg atacttctcc acttaatgtt gggatcgacc tatgcttgga
      121 gtgtttatcg taatccaatt ttacaagaga ccggttggga tcaagctcct gtcgcttttg
      181 ccttttcttt agctattttt tgtttaggtt tatctgctgc ttttatggga aatttagttg
      241 aacaatatgg tcctcgtcta accggaacgg tgtcggctat tctttatgct tctggaaata
      301 tgctgactgg tttagcgatt gatcgtaaag aaatttggct tttatatatt ggttatggtg
      361 ttattggtgg cttaggactt ggagcgggat atatcacacc gatatcaact attataaaat
      421 ggtttccaga taaaagaggc atggcaacag ggtttgctat tatggggttt ggttttgcgt
      481 ctttattaac aagtccgatt gcccagtggc taattgaaac agaaggtttg gtagcaacat
      541 tttacctttt agggctgatt tatctaatag ttatgctttt tgcttctcaa ttgataataa
      601 aaccaactgc tgctgagata gctatactag ataaaaaaag attacaaaat aacagttatt
      661 taatcgaagg aatgaccgct aaagaagcac ttaaaacaaa atcattttat tgtctttggg
      721 taattttatt tatcaatatc acatgtggct taggacttat ctcagttgtt gcgccaatgg
      781 cacaagatct aactggtatg agtccagaaa tgtcagcaat tgtggttggt gctatgggga
      841 tttttaacgg tttcggtcgt ttagtgtggg ccagtttgtc agactatatt ggacgccgtg
      901 tgacagtaat acttttattt ttagtaagca taattatgac tattagttta atatttgcac
      961 atagttccct aattttcatg ataagcattg ccacccttat gacttgttat ggtgcgggtt
     1021 tttctctcat tccgccttat ttaagtgatc tttttggggc aaaggaactg gctacattac
     1081 atgggtatat attgacagct tgggcaatag ctgcattaac tggacctatg ttattatcta
     1141 tcactgttga atggactcat aattatcttc ttaccttatg tgtttttatt gtcttataca
     1201 ttttaggatt aatggtagca ttaaggttaa agaaatgatg tcctataaaa aatttaaaag
     1261 taaaccctag caaagcctag ggttttttta tataattagg tttatggtta aatcatacag
     1321 taaaacagca aatcataata tgcgtcgtcc tgttgtcaaa gaagagcttg ttcattatat
     1381 gcgaacacgg cagaagcaaa tcacaggttt tttagcagag ttagagcaat tcgcaagaca
     1441 agaaaacatt cctattattc agcctgaggt cgtggcttat ttcaggtttt tattgcaaag
     1501 cttacagcca aaacacattt tggagattgg cacagccatt ggtttttctg cgcttttaat
     1561 ggctgaaaat gcaccagatg cgacgattgt gactattgat cgtaatcgag agatgatcga
     1621 ttttgctaaa gcaaattttg ctaagtacga cagtcgccaa cagatccgcc tgttagaagg
     1681 agatgcagca gatatattat ctacacttga aggaaatttt gactttgtgt ttatggattc
     1741 cgccaaatcc aaatatattg tctttctacc agagatttta agactgttaa aagtcggtgg
     1801 tgtagtcatt ttggatgatg tctttcaagg aggtgacatt acaaaaccga tcgaagacat
     1861 tcgacgaggt cagcgtacta tttatcgtgg cttacagtct ttgtttgatg ctaccttaac
     1921 tcatccaaac ctaacaacta gcctggtccc tcttagtgat ggattattaa tgattcgtaa
     1981 aaatcaagca gatattctat taccagatta agtaacattg ataaatttat gttataataa
     2041 attagttaaa gataaaaagg agctcagaag taaatgaaaa actcaaataa actcattgct
     2101 agtgttgtga cattggcctc agtgatggct ttagcagctt gtcaatcaac taatgacaat
     2161 actaaggtta tttcgatgaa aggtgataca attagcgtta gtgattttta caatgaaaca
     2221 aagaacacag aagtatcgca aaaagcgatg ctaaatctgg taattagtcg tgtttttgaa
     2281 gctcaatatg gtgataaggt ttcaaaaaaa gaagttgaaa aggcgtatca taaaacagct
     2341 gaacagtatg gcgcttcatt ctctgctgct ttggcacaat caagcttgac acctgagact
     2401 tttaagcgtc agatccgctc ttcaaaatta gtagaatatg cggttaaaga agcagctaaa
     2461 aaagaattga caacacaaga atataagaaa gcatatgaat cttatactcc aacaatggca
     2521 gtcgaaatga ttactttaga taatgaagag acagctaaat cagtcttaga ggaactaaaa
     2581 gccgaaggcg cagactttac agctattgct aaagaaaaaa caacaacacc tgagaaaaaa
     2641 gtgacctata aatttgattc aggcgcgaca aatgtaccga ctgatgtcgt aaaagcggct
     2701 tcaagtttga atgagggtgg catatcagac gttatctcgg ttttagatcc aacttcttat
     2761 caaaagaagt tttacattgt taaggtgact aaaaaagcag aaaaaaaatc agattggcaa
     2821 gaatataaga aacgtttgaa agctatcatt atagctgaaa aatcaaaaga tatgaatttc
     2881 caaaacaagg ttattgcaaa tgcattggat aaagctaatg taaaaattaa agacaaagct
     2941 tttgctaata ttttggcgca atatgcaaat cttggtcaaa aaactaaagc tgcaagtgaa
     3001 agttcaacaa ccagcgaatc atcaaaagct gcagaagaga acccatcaga atcagagcaa
     3061 acacagacat catcagctga agaaccaact gagactgagg ctcagacgca agagccagct
     3121 gcacaataag taggatttta ttgactaatc agttaaaaaa acttataata atttagttaa
     3181 gaattgttta tcaaggatta gatacagaaa agtgacggtt gctgcgagtc attgataatt
     3241 agataaacat gctacttaac tttacaacaa ttgatatcgt aaattaagaa tgacaagttc
     3301 attgaataga ggtggtaccg cggttttcgc cctctgtgag atggacttgt tttgtattga
     3361 ggactatttg aaatcaacga aaggaataga gtagactagg ctgccaggct tatagctgat
     3421 ctcctagcaa gaaagacgag ctgtgtcaac tggtgtgatt acattactag cttcagcata
     3481 acactgtttt tcttactctt tgtatctaaa tttttatgaa agaattatcg tctgcacaaa
     3541 tccgccaaat gtggttggat ttctggaaat ctaaaggaca ttgcgttgag ccttcagcta
     3601 acttggttcc tgtgaatgac ccaacgcttc tttggatcaa ctcaggtgtt gcaaccttga
     3661 aaaaatactt tgatggttca gtgattccag aaaatccacg tattaccaat gcacaaaaat
     3721 caattcgtac taatgatatt gaaaatgttg gtaaaacagc acgtcaccat actatgtttg
     3781 aaatgcttgg taacttctca attggagact atttccgtga tgaagctatt gagtggggat
     3841 ttgaactctt gacaagtcca gactggtttg atttccctaa agataagctc tacatgactt
     3901 attacccaga tgacaaggat tcatataacc gttggattgc ttgtggcgtt gaaccaagtc
     3961 acttggtgcc gatcgaggat aacttctggg aaatcggtgc tggtccttca ggtccagata
     4021 cggagatttt cttcgatcgt ggtgaagatt tcgatccaga aaatatcgga cttcgcctct
     4081 tggctgaaga tatcgaaaac gatcgttaca tcgaaatctg gaacatcgtt ctctcacaat
     4141 tcaatgctga cccagccgta ccacgttcag aatacaaaga attaccaaac aaaaacattg
     4201 atacaggtgc tggtcttgaa cgtcttgcag ctgttatgca aggggcaaaa acaaactttg
     4261 aaactgacct cttcatgcca atcatccgtg aagtagagaa gttgtcaggt aaaacttata
     4321 atccagatgg cgacaacatg agtttcaagg ttatcgctga ccacatccgt gcgctttcat
     4381 ttgctatcgg tgatggtgcg cttcctggaa atgaaggtcg tggttacgtt cttcgtcgtc
     4441 ttctccgtcg tgctgttatg catggtcgtc gtcttggcat caacgaaact ttcctttaca
     4501 aattggttcc gactgttgga caaatcatgg aaagctacta cccagaagtg cttgaaaaac
     4561 gtgattttat cgagaaaatc gttaaacgtg aggaagaaac atttgctcgt actatcgatg
     4621 caggtagcgg tcacttagat tcattgcttg cgcagcttaa ggctgaaggt aaggatactc
     4681 ttgaaggtaa agatatcttc aaactttatg atacttatgg attcccggtt gaattgacag
     4741 aggaattggc agaagatgca ggctacaaga ttgatcacga aggctttaag tcagccatga
     4801 aagaacaaca agaccgtgcg cgtgcagctg ttgttaaggg tggttcaatg gggatgcaaa
     4861 atgaaaccct agctggtatt gttgaagaat cacgattcga atacgacaca tatagtcttg
     4921 aatcaagtct ttcagtcatc atcgctgata atgaacgtac cgaagctgtt tcagaaggtc
     4981 aagctcttct tgtctttgct caaacaccat tctatgctga aatgggtgga caggttgctg
     5041 acacaggtag aatcaaaaat gataagggtg acacagttgc tgaggttgtt gatgttcaaa
     5101 aagcaccaaa tggtcaacct ctacacactg taaacgtttt ggcatcactt tcagttggaa
     5161 caaactacac acttgaaatc aacaaagagc gtcgtttggc tgttgagaaa aaccacacag
     5221 caactcactt gcttcatgca gcccttcaca atgttatcgg tgaacacgca actcaggctg
     5281 gttcattgaa cgaagaagaa ttcttgcgct ttgattttac tcactttgaa gcagtaagca
     5341 atgaggaact tcgtcacatt gaacaagaag ttaatgagca aatttggaac gctcttacga
     5401 tcacaacgac tgaaactgac gttgaaaccg caaaagagat gggagcaatg gcactttttg
     5461 gtgagaaata tggtaaagtg gttcgtgtgg ttcaaattgg taattattct gttgaacttt
     5521 gtggtggaac tcacttaaat aattcttcag aaatcggtct cttcaagatt gtcaaagaag
     5581 aaggtattgg ttcaggcact cgtcgtatta ttgcagttac tggtagacaa gcttttgaag
     5641 cttatcgtaa ccaagaggat gccctaaaag agatcgctgc tactgtaaaa gctccgcaat
     5701 tgaaagatgc agcagctaaa gtacaagctc ttagcgactc acttcgtgat cttcaaaaag
     5761 aaaatgcaga gcttaaagaa aaagcagcag ctgcagcagc tggtgatgtc tttaaagatg
     5821 ttcaagaagc taagggcgtg cgcttcattg ctagtcaagt tgatgttgca gatgcagggg
     5881 cacttcgtac atttgctgat aactggaaac aaaaagacta ctctgatgtg cttgttctcg
     5941 tagcagctat tggtgagaag gttaatgtcc ttgttgcaag caaaactaaa gatgtccacg
     6001 ctggtaacat gatcaaagaa ttggcaccaa ttgtagcagg tcgtggtgga ggtaaaccag
     6061 acatggctat ggcaggtggt agcgatgcaa gtaaaattgc agagctgcta gcagcagttg
     6121 ctgaaacagt gtaaatccat aaaaaaccaa gttatttaga acttggtttt ttatatttga
     6181 aatgactacc atcataacct ttttgactat tatcgttgtc aaaaagaaaa agatatgtta
     6241 caattatagt aacaaataga catgaggagg tgttagagaa aatgacacat ggtatcaaac
     6301 ttaagaggca gatttgctta tgggcaagta tcctgactct tttcatttta agttatcatc
     6361 ttatcagggt aatctggttt ggagtaccct tgagttatct ggttttgggc tttacaggac
     6421 tagccttgct gttgaatact ttttcttatt ttagaaagta agttataagt taaagaagaa
     6481 tgaaggagat ggcaatggag gttattctta aaaatcggct caaagaatta cgagccagag
     6541 atggaattaa tcaaacggaa atggctaaac tggcaggagt atcgaggcag accatcagtc
     6601 tcattgagcg taacgagtac accccatcag ttataattgc catgaaaatt gcaaaggtat
     6661 ttcaggaacc agttgaagag gtgtttcgtc tagtggaggt cgaggaatga aaaagaagaa
     6721 gaatagtttt ttacgcttgt taaaaatgtt attgctatca agtttggcgg gagggattat
     6781 aggtggcatg gttggagcct ttttaggtta ccatggagag agattagatc agctcacgtt
     6841 cctaaaagat gatgtgatta acctgattat cttattaaat cgtctagtag ttgtcacagg
     6901 cctcacactt tcctttgttt ttttaacgca actgaaaaaa gagacagctg tttataacac
     6961 aattgaagag gatgattatt ctgaaaatgg ttaccgtcag ctgaataaaa agcatgctta
     7021 taccatgtta ttgattgccg tagcttctat tttatccatg tgcaatgtgc tacttggtct
     7081 gaccttaact aatgattcac agcatgccat gctggccatt ccgcttctgg atatcctttt
     7141 attattaatg gtcattcctt ttcaagcttt agccatgaaa cgttacaatg ccattcgggg
     7201 aaccgatgtt ccttattttc caaatttgaa agaattaaaa cataatatca tggctctaga
     7261 tgaggcagag ttacaagcct atcataagac atcgtttgaa agtgtgttgt cattaaatgg
     7321 agtcatcatc ccttccttgt atgtgatttt attttttgtc tatctattca ctggtcaagt
     7381 ggagttaaca gccatcttag ttttggtgtt aattcagctc tatttactcg ttaagagtgc
     7441 aacaatgacc agacaatttt accgttagcc taaaaggaga ctgtttatga aaggattcat
     7501 taattattta aaaatagcag tgctcattat tctggctatg gttttcaatg tccttccgat
     7561 gattttattg caaaagcaac acgatattcc tatggtgctt aattggggaa ttggtatttt
     7621 ctacttggtt attgttggaa gtgtccttat tgtattatgg cgtctttatc aagctaagca
     7681 agacacccct attaaacagc aaaaaatgag attggttgac tggggttatt tagcattatt
     7741 ttggttaatc atccgtgtga tagctattgc aggtaccctt gttaaccagc tatggtctgg
     7801 tcaacaagtg agtgctaatg atgctgcaat acatacctta gctagactta tcaaaggtgg
     7861 tttcccgctt tatactgccc tatttgtact tgtgatagct tttatcgctc ctattatgga
     7921 agaactagtc tttagaggat ttcctatgat tgatctcttc aaaggaaaat cacttaaggt
     7981 ggcaggttta gtgacctctc ttgtttttgc tttaccacat gccaccaata gtgttgaatt
     8041 tatcatgtac agctgtatgg gcatttttct ctttgttgcc tatcaaagac gaggaaactt
     8101 aaaagacgct atcttgttac atatttttaa taacttgatt gaagtcattt tgttaatgtc
     8161 aataggctta ggagtcatat aataaaaagc ttcggatgga tgaactgcac cccaaaagtt
     8221 ggacaaaaaa atctaacatt tgggttggaa ttgtcaagaa aaaatagaca taaagttaag
     8281 ctaatgagta actatttttt tcaaattcaa caggtgagag ataccctaaa gctgaatgca
     8341 gacgtttggg gttatagtaa gtctcactat atttaaaaat ctcaagctta gcttgctcaa
     8401 tagttgcgaa atgagcatca ttgacaagct ctctttttaa tgttttataa aaggattcca
     8461 tgagtgcatt atcgtatgga ttaccttttc gactcatcct ggacttacat tttttccatc
     8521 taagtaggtc ctgaaatcgt gctccggtat attgagaacc ctgatctgta tggacgatta
     8581 ccccttcttt aggcttttct ctattataag cttgattgaa agcttctgtt accaacttgt
     8641 cttgcatacg ttggcccatt gcccaaccaa caacctttct actataaacg tctatcaaga
     8701 cagacacata aagtattcct tcttgtgtag gaatgtaggt taggtctcct agccataatt
     8761 tattcttacc agtcgcttgg aaacattgat taacaagatt gggacgagtt catgaagaac
     8821 gtcgacggtt atagtattta tattgatatc gacttccttt agcatagag
//
LOCUS       DATWVB010000052         8812 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.052, whole genome shotgun sequence.
ACCESSION   DATWVB010000052 DATWVB010000000
VERSION     DATWVB010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8812
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.052"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            53..919
                     /locus_tag="VCX65_001557"
     CDS             53..919
                     /locus_tag="VCX65_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEP5054009.1"
                     /translation="MKMKKKFFLLSLLVLSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            930..1865
                     /gene="pstC"
                     /locus_tag="VCX65_001558"
     CDS             930..1865
                     /gene="pstC"
                     /locus_tag="VCX65_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEP5054010.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFVDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTILSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATCWQTIWRVVLNAARP
                     GIFTAIIFGMARAFGEALAIQMVVGNSAVMPSSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            1855..2742
                     /gene="pstA"
                     /locus_tag="VCX65_001559"
     CDS             1855..2742
                     /gene="pstA"
                     /locus_tag="VCX65_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEP5054011.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGSLALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSARFIGKKLHSKMTAAK"
     gene            2758..3561
                     /gene="pstB"
                     /locus_tag="VCX65_001560"
     CDS             2758..3561
                     /gene="pstB"
                     /locus_tag="VCX65_001560"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEP5054012.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            3574..4332
                     /gene="pstB"
                     /locus_tag="VCX65_001561"
     CDS             3574..4332
                     /gene="pstB"
                     /locus_tag="VCX65_001561"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEP5054013.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            4400..5053
                     /gene="phoU"
                     /locus_tag="VCX65_001562"
     CDS             4400..5053
                     /gene="phoU"
                     /locus_tag="VCX65_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEP5054014.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            5258..7795
                     /locus_tag="VCX65_001563"
     CDS             5258..7795
                     /locus_tag="VCX65_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEP5054015.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTPRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIDNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNQHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQNNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQPTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
     gene            8142..>8812
                     /locus_tag="VCX65_001564"
     CDS             8142..>8812
                     /locus_tag="VCX65_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5054016.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGY
                     ILKNN"
BASE COUNT         2710 a         1486 c         1808 g         2808 t
ORIGIN      
        1 gcacttagtt tctacatata taccctttat ttttacgaat aggaaataaa taatgaaaat
       61 gaaaaaaaaa ttctttttgt taagtctttt ggtcctatca actttctttt tatccgcatg
      121 ttctagctgg attgataaag gtgagtcaat aaccgctgta ggatcaacag cactacaacc
      181 cttagtagaa gcagtagctg atgaatttgg aagcagtaat ctaggcaaga ctgtcaatgt
      241 tcaaggtggt ggttcaggta cagggttgtc tcaagttcaa tcaggagctg tccaaattgg
      301 aaatagtgat gtctttgcgg aagaaaaaga tggtattgat gcttctaaat tagttgatca
      361 tcaagtagct gttgcaggac ttgcagttat tgccaatcct aaagtcaagg tttccaatct
      421 cagtagtcag cagttgcaaa agattttttc aggagaatat accaattgga aacaagttgg
      481 aggagaagat cttgcgattt cagtgatcaa ccgagcagca agttctggct cacgagcaac
      541 ctttgacagt gttatcatga aaggggtcaa cgctaaacaa agtcaagagc aagactccaa
      601 tgggatggtt aaatcgattg tttcacaaac accaggtgcc atttcttacc tttcctttgc
      661 ctacgttgat tcatctgtta aatctttgca attaaatggg tttaaggcaa atgctaagaa
      721 cgtggctaca aatgattggc caatctggtc ctacgaacac atgtatacca aagataaacc
      781 aacagggttg accaaggaat ttcttgatta tatgttttca gatgaagtac aacagaacat
      841 tgttacacat atgggatata tttcgataaa tgatatggaa gtggtcaaat ctcatgatgg
      901 aaaagtaaca aaaaggtaat ggaggaatta tggaaaatca ggaattggct aaaaaattag
      961 cctcaccatc aaagaattca agacttgaaa cctttggccg caccattacg tttttgtgtc
     1021 tggctttgat tgtttttatc gttgcgatga ttctgatctt cgttgctcaa aaagggttgt
     1081 caaccttctt tgttgacaag gttaatcttt ttgatttctt gtttggaaag gagtggcaac
     1141 caagtgtgaa aaatgcggcc ggcattcctt atcttggtgc tctgccaatg attacaggat
     1201 cctttttggt taccatttta tctgctatta ttgccacccc atttgccatt ggcgcagccg
     1261 tttttatgac tgaaatctca cctaaatatg gcgctaaatt attacagcct gcggttgagc
     1321 ttttggttgg aattccttcg gttgtttatg ggtttatcgg tttgcaagtg attgttcctt
     1381 ttatgcgctc tatctttggt ggcacaggtt ttggaatcct atctggggtc tgtgtcttgt
     1441 ttgttatgat tttaccaaca gtgactttta tgacaacaga cagtctgcgg gcggtgcctc
     1501 gtcattaccg cgaagcgtct atggctatgg gagcaacctg ttggcaaacc atttggcgtg
     1561 ttgttcttaa tgcagctcgt ccaggtattt ttactgccat tattttcggg atggcgagag
     1621 cttttggtga agccttagcc attcaaatgg ttgtcggtaa ctctgctgta atgccaagtt
     1681 cactaacgac accagccgca accttaacgt ctgtcttgac aatgggtatt ggtaacacgg
     1741 ttatgggaac ggtccaaaat aatgtgcttt ggtcccttgc cctagtctta ttattaatga
     1801 gtctggcctt caattccctt gtcaaattaa tcacgaaaga aagaaagaga aattatgaac
     1861 gctaaaaaag tcgataaagt agcaactggt actctttata ccattgctgg aattattgta
     1921 gctattttag cttccttaat tctatatatc cttgtccgtg gcttgccaca catcagctgg
     1981 tcctttttaa caggaaaatc gtcttcgtac gaagctggtg ggggaattgg tatccagttg
     2041 tataattcct tcttcctatt gattgttacc ctgattattt ccattccttt atcaactgga
     2101 gcggggattt acttggctga atatgccaaa aaagggcctg ttaccaactt tattagaacc
     2161 tgtattgaga ttctgtcttc cctaccatct gtggttgtag ggctctttgg ttacttgatt
     2221 ttcgttgtgc agtttgaata tggcttttct attatttcag ggtctcttgc tttgacggtc
     2281 tttaatcttc ctcaaatgac ccgtaatgtt gaagatagtt tactgcatgt tcatcatacc
     2341 caaagagaag caggattagc tttaggcctg tcacgctggg aaacagtttt ttatgtggtt
     2401 atcccagaag ctctcccggg gatggtaaca ggtattgtct tagcttcagg tcgtattttt
     2461 ggtgaagcgg cagcgcttat ctatactgct ggtcaatcag caccagctct ggattggtca
     2521 aattggaatc cacttagtgt tactagtcca atctctattt tccgtcaatc tgagaccctt
     2581 gctgttcata tttggaaagt caatagcgaa gggacaattc cagatgctac tcttgtatcc
     2641 gcaggaagtg cagcagtgct attaattttt atccttattt tcaacttttc agctcgcttt
     2701 attgggaaga aacttcattc taaaatgaca gcagcgaaat aagatattgg agaaatcatg
     2761 acagaatata attggaatga acgtcatatc atcacttttc ctgaagaaac gcttgctcta
     2821 gctaccaagg atttacatgt ttactatggt gcgaaagaag ctatcaaagg gattgatatg
     2881 cagtttgaaa aacataaaat aacagccttg attggtccat ctggttgtgg caaatcaact
     2941 tatcttcgta gtcttaaccg catgaacgat accattgata ttgctcgggt tacaggtgag
     3001 attctttatc agggcattga tgttaatcga aaagacatga atgtttacga gattcgcaag
     3061 cacttaggaa tggtttttca aagacccaat cctttcgcta aatccattta taaaaacatt
     3121 acctttgccc atgaaagagc tggtgtgaaa gacaaaaaag ttttagatga aattgttgag
     3181 acttcactga aacaagccgc gctttgggat caagttaaag atgaccttca caaatcagcc
     3241 ttcaccttat cagggggtca gcaacaacgc ttgtgtattg ctagagccat ttctgtcaaa
     3301 cctgatattc tattaatgga tgaaccagcc tctgcccttg acccgattgc aacgatgcag
     3361 ctggaagaaa ccatgtttga attgaagaag aattacacga ttattattgt gacccacaat
     3421 atgcaacaag cagctcgtgc cagtgattac actgccttct tctatttagg caacctcatt
     3481 gaatatgata agacacgtaa tattttccaa aatgcgcaat gtcagtcaac aaacgactac
     3541 gtttcagggc actttggtta gaaaggtaat atgatgacag aacctatttt acagatcaga
     3601 gacctttctg tttactacaa tcaaaagaaa acgttaaaag atgtctcttt ggacctttat
     3661 ccaaatgaaa taacagcttt aattggtcct tctggatctg ggaaatcaac gctcttgcgt
     3721 tctatcaacc gtatgaatga tttgaatcct gaagtaacca ttacaggctc tatcgtctat
     3781 aacggacaca atatttatag tccaaggaca gatacggttg atctacgcaa agaaattggt
     3841 atggtattcc aacaacccaa cccatttccg atgtctattt atgagaacgt ggtttacggc
     3901 cttcgcttaa aaggtatcag agataaatca atcttagacc atgctgttga aagctctctt
     3961 aaaggggctt ccatttggaa tgaagtcaaa gatcgtttac atgattctgc ggttggctta
     4021 tcaggcggac agcaacagag agtttgcata gctagagttc ttgctaccag ccccagaata
     4081 atccttttag atgaacctac ctcagctctt gatcctatct cagctgggaa aattgaagaa
     4141 acattattgt tattaaaaaa agattataca ctggctattg tgacccgctc aatgcagcaa
     4201 gcctcacgtt tatcagatcg aacaggtttt ttcttggagg gtgacttact tgagtgtggt
     4261 cctacaaaag ctatgtttat gaatcctaag cgcaaagaaa ccgaagacta tatttctggt
     4321 aaatttggtt gagaaagacg tatatggttg acccctctgt gtttttatta taatgactag
     4381 attgtaggaa gaaaaaatca tgttaagaac gaaatttgaa gaagaattag ataaattgca
     4441 taaccagttt tattcaatgg gaacggaagt attggcacaa atcaataaaa ctgttcgtgc
     4501 ctttgttagt catgatcgtg aattggccaa agaagttatc gaagaagatg acactattaa
     4561 taattttgag acaaagcttg aaaagaaatc gctggaaatt attgccctac aacagccagt
     4621 ttcgaatgat cttagaatgg ttattactgt tttaaaggca tcaagtgata ttgaacgtat
     4681 gggtgaccat gctgcttcga ttgccaaggc cactattcgt atgaaaggtg aggagcgtat
     4741 tccagtggtt gaagaacaaa tcaaccttat gggaaaagct gtgaaacaga tggtagaaga
     4801 agcccttaat gcatatatca atgctgacga tacaaaagct tatgaaatcg cagcttctga
     4861 tgagattatc gatcaatatt tccgtaatat ccaaacctta gctgttgaag aaatccgtaa
     4921 gtctccagat gctgtttttg caggaaaaga atattttcaa gtattaatgt atttggaacg
     4981 tattggtgac tatgctcgca acatttgtga atggattgtt tatcttaaaa ctggaaaaat
     5041 tattgaatta taagaaatta tgctataatg agactgggaa acagcttgcc agtccctggt
     5101 tttatacgaa attgtgcaag ttagaaaatg aactaacaag aaaagttttc tttgctgaat
     5161 ctgattttgt taggttaaca aatatatgta gacagagatg atacttaggt atcatctgtt
     5221 gatctattat gatttgttat tagaattaag gagttatatg aagacagtag aacatctcat
     5281 cgaaacattt gtgcctgaaa attataacat ctttttagat attaatcgtc agactaaaac
     5341 atttacgggg aatgttgcga ttaatggtga agctttagat aatcatgtgg ctttccacca
     5401 aaaagatttg gacattaagt ctattttgct cgataatgaa gctgttattt atcaagtgga
     5461 taacgacaat gaagttgtgc gtgttgaatt acctgaaaca ggaatgatga cgcttgtcat
     5521 tgaattttca ggtagcatta cagataatat gacaggtatt tacccttcat attacactaa
     5581 aaatggtgag aaaaaagaag tcatttcaac tcagtttgaa agccattttg cacgtgaagc
     5641 tttcccatgt attgatgaac cacaagcaaa agctactttt gatttaagct tgacctttga
     5701 tcaagaaatt ggtgagatag cgttatcgaa tatgccagaa gtcaatattg accgtcgcga
     5761 ggagactggt ctttggacat ttgatacgac accaagaatg tcatcttact tgctagcgtt
     5821 tgcgctagga gaacttcatg gaaagactgt agaaagcaaa aaaggaacaa ctgttggtgt
     5881 gtatgcgaca acagcgcatc ctcttagctc gcttgatttt tcattggata ttgcagttcg
     5941 tgttatcaac ttttatgaag actattttgg agtacattac ccaatcccgc aatctcttaa
     6001 tattgcgctt ccagattttt catctggtgc tatggaaaat tggggtttaa tcacttatcg
     6061 tgaaatttat ttattagtag atgaaaattc gactgttcaa agccgacaac aagttgcact
     6121 tgtaatcgcc cacgagatag cacaccaatg gtttggaaac ttggttacaa tgaaatggtg
     6181 ggacgatctg tggttaaatg agagttttgc caacatgatg gaatatgtct ctatcgaggc
     6241 tattgagccg tcttggaaaa taatagaaga tttccaaaca ggtggtattc ctcttgcttt
     6301 aaaacgtgat gctactgatg gtgttcaatc agtgcatgtt gaagtcaatc atccagatga
     6361 gataaataca ttgtttgatc ctgctattgt ctatgcaaaa ggtagtcgtt tgatgcatat
     6421 gttacgccgt tttattggtg atcgtgattt tgccattggc ttacatcact actttgaaaa
     6481 atatcaatat cgaaatactg tcgggcgtga tttatggaat attttatcag atacttcagg
     6541 caaagacgta gctgctttta tggatgcttg gcttgaacaa ccaggttatc cagttttaac
     6601 agctcgcctt gaaaacgatc aattgatttt gagtcaaaaa caatttttta ttggaaaagg
     6661 tgaagaaaaa ggtcgccttt ggccgattcc tttaaacact aattggcatg gccttcctga
     6721 aactttgaca gaggcagaaa tggtcattcc aaactttagt caattggcag cagaaaatga
     6781 aggagctcta cgtttcaata ttgataatac agctcattac attacagact accaaggatc
     6841 attattagat gccttagtca ctgaacttgc ccaacttgat aatacttctg ctttacaagt
     6901 tattcaagaa cgtcgtttat tggcagatag tggcttgatt tcctatgctg aattggttga
     6961 cttaattgct caattggacg attctaagtc ttatatggta gcagaagcgg ttcagcaagt
     7021 ggtctctggt ttgaaacgct tcattgatga aggaagctta gcagaaaaat cctttaatcg
     7081 cttggtaacc accatctatc aagaagactt taatcagcat ggttttgaga aaaaagctga
     7141 cgaatcagat gaagatgaga tggtacgtca ggttgccttg ggccgcttgt ggctagcaga
     7201 aaatcagacg attattgacg gattgagaac tatttttgaa gcatatcaaa acaatattgc
     7261 aagtattcca gcagctgttc gtcgcttggt tttagccaac caaatgaaat attttgaaac
     7321 agatagcttg gttgatattt attttgagac ttatgtagca actactgata ataatttacg
     7381 cagtgattta acggttgctt ttagtcaaac aaaacaacca actactatta gacgtattct
     7441 tgttagttta aaagataaag atattattaa acctcaggat ttatcttatt ggtacaatgc
     7501 tttgcttgga caaagcttta ctcaagatat catttgggaa tgggctagag aaaattggga
     7561 ttggattaaa tctgcacttg gtggagatat gagctttgat aaatttgtta tttatccagc
     7621 aagtaacttt aaaacaccaa aacatctagc agaatataaa tctttctttg aacctaagct
     7681 agatgatatg gctattagcc gtaatattac catgggaatt aatgaaattg aagcacgtgt
     7741 tgctttgatc actaaagaaa aagaagcagt tattgcagct ctcagtcatt actagaccat
     7801 aagcaaaaga gttgggagga ctttccagct cttttttgta gtgagctagc ttcctttctt
     7861 agttccgtct ataactaaat gattatccat agtttaattc aaaaggagat tgcactttaa
     7921 agcgaaggct attagcctct taatactttt tttaccaggt ggtgaataag aacaattata
     7981 aatgatttaa tcattatgct ttaaatgcct taaaggagta ttaatatttt agtaaacctt
     8041 aagctttttg tagtatagtc tcgttagaaa ttgttatcag aaatgagact aagttaaatg
     8101 aagtgatagt tactttattt aagaacaatt gaggtagaga catgataaaa atattattag
     8161 tagaagatga cttgagctta tcaaattcca tttttgattt tttagatgat tttgcagacg
     8221 tcatgcaagt ttttgatggc gatgaaggtt tatacgaagc agaaagtggt atttatgatt
     8281 tgattttgtt agaccttatg ttgccggaga aaaatggctt tcaagtctta aaagaattgc
     8341 gagaaaaaga tattaaaatt cctgtattga tcatgacagc taaagagggt ttagatgata
     8401 aaggtcacgg atttgaatta ggtgctgatg attatctgac aaagccgttc tatttagaag
     8461 agttaaaaat gcgaattcaa gcactgttaa aaagaacagg gaaatttgca gataaaaata
     8521 ttagttttgg caatttagtg gtcgacttag ctcgaaaaga ggtgaaggtt gaagggaaag
     8581 tagttgaatt acttggcaaa gaatttgatt tgttggtgta tcttttgcaa aatcaaaacg
     8641 ttattttacc aaagacacaa atttttgatc gtttatgggg attcgatagt gatactacga
     8701 tttcggttgt tgaagtttac atttctaaaa taaggaaaaa attaaaaggt acccgttttg
     8761 ttaacaggct tcaaacttta agaagcgtag ggtatattct aaaaaacaat ga
//
LOCUS       DATWVB010000053         8767 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.053, whole genome shotgun sequence.
ACCESSION   DATWVB010000053 DATWVB010000000
VERSION     DATWVB010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8767
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.053"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            410..612
                     /locus_tag="VCX65_001565"
                     /pseudo
     CDS             410..612
                     /locus_tag="VCX65_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            814..1194
                     /locus_tag="VCX65_001566"
     CDS             814..1194
                     /locus_tag="VCX65_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEP5054017.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            1194..2042
                     /locus_tag="VCX65_001567"
     CDS             1194..2042
                     /locus_tag="VCX65_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP5054018.1"
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            2167..3375
                     /locus_tag="VCX65_001568"
     CDS             2167..3375
                     /locus_tag="VCX65_001568"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEP5054019.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDH
                     IEALDQALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            3372..5249
                     /locus_tag="VCX65_001569"
     CDS             3372..5249
                     /locus_tag="VCX65_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEP5054020.1"
                     /translation="MSHFLVKKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQ
                     YELLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDATNLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRIFYGSYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYGQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
     gene            complement(5347..5424)
                     /locus_tag="VCX65_001570"
                     /pseudo
     CDS             complement(5347..5424)
                     /locus_tag="VCX65_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            6141..6551
                     /locus_tag="VCX65_001571"
     CDS             6141..6551
                     /locus_tag="VCX65_001571"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEP5054021.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(6634..8646)
                     /locus_tag="VCX65_001572"
     CDS             complement(6634..8646)
                     /locus_tag="VCX65_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HEP5054022.1"
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGAL
                     DNTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANS
                     ALLQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEH
                     EASHQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQ
                     NYEHYQFLDAAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQI
                     YPEHSIDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFMTTPSAN
                     VIAVAPGIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNL
                     VTTAQLTIAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQM
                     TGQHIYDVLNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLT
                     TTYTVVVNDFLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGV
                     KNYVTSNLESSTKVNSAGKHSIISKVFRNRDGNIVSSEIISDLLTSTENTNNSLGKKE
                     TTTNKNTISSSTLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
BASE COUNT         2810 a         1401 c         1798 g         2758 t
ORIGIN      
        1 aataattttt aataaacgta aacaagcgat tgacaatgga gatatcacaa gagatacagt
       61 agtggttgtg cttaaaatgg acggtttttt gatgatatgt tgccgcatga ggaagtgagc
      121 aataggagag ctgtgataga agaaagagag gaagaagcgt tgatgaaatt agacaaataa
      181 aaaaaaagac ctcatccaga agaggtcgtg gtataactgg ggacgatagg ttcaattgat
      241 aaaaaatctt gttagcttac gatctatgtt gttttgaatg cctttaactc aacatcgtta
      301 atggattttg agataaaaaa ataaatccaa tagtctggta ctttcctatt ttttgtctgt
      361 taaaacgttt ttattttata atggataaaa ggagaagaag ggcggagcga tgattaagct
      421 ctatgggttt aagtatgggt tagttggaga ggttttgcgg cggattgaac gcctaggatt
      481 tacgtttgag cgattagagc taagacaagc tagttcgaaa tacttggcta agcatgatga
      541 ggccttggtg ataaaccttt ttatcctgga cttaaaactt acctgaccag tggttctgtt
      601 ttaattgagg tgcagtacaa gaccactaac gggtgttttt ttgatataat gtcagtataa
      661 ggacgactaa atataaatag gtgaaaaaat agatatctgt tcgagagata gcactgttta
      721 aaacgttatg cgaaaatagt agtttagggg ctactttaat aatcttcaaa tctatgctat
      781 aatggatcat attgatacca aggagaataa aaaatgcaat tagttcgtga aaaagaattt
      841 gtcaaccagt accattatga tgctagaaat ttagagtggg aaaaagaaaa cggaacacca
      901 gagaccaatt ttgaagtgac ttttcagttg attgataaag atgagcagca aaaagaaaca
      961 gtaattgtat ctgtattgca atttgttatt gtcaaagaag aatttgttat tagtggggtc
     1021 atctcacaaa tggttcgtat tttagatcgt ttagtggata aaccaagcga atttacgcaa
     1081 gaggaagttg aatccttagc tgctcctttg ctagacatgg ttaagcgatt gacttatgaa
     1141 gtcacagaaa ttgccttgga tcgtccaggt attcatttgg agtttaaaaa ttaatgaaat
     1201 tagcagtaat tactgacagt acagcaacac taccaacaga tctgaaacaa gataaagcta
     1261 tttttagcct tgatatacca gttatcattg acgatgagac ctattttgaa ggtcgaaatt
     1321 tgagtataga tgatttttat caaaagatgg ctgactccca aaatcttccc aagacaagtc
     1381 agccaagttt atctgaacta gataatcttt taggactttt gtcttctaag ggctatacac
     1441 atgttattgg cttgttctta gctggaggaa tctcaggctt ttggcaaaat attcaatttt
     1501 tagctgaaga acatcctgag attgaaatgg catttccaga cagtaagatc acatctgctc
     1561 ctttaggtag tatggtaaaa aatgtgctag attggtcacg tcaaggaatg acatttcaag
     1621 ctattttaaa caagctgcaa gaacagattg atgggacgac agcctttatt atggttgatg
     1681 accttaatca tctggttaaa ggcggacgcc tgtcaaatgg gtctgctctt cttggaaatc
     1741 ttttgagtat taaacctatc ttacgctttg atgaagaggg aaaaatcgtt gtttatgaaa
     1801 aagtgagaac agaaaagaaa gccatgaaac gcttggttga gattttaaat gacttgatag
     1861 cagacggtca gtataatgtg tctattattc actcaaaagc acaagacaaa gctgattatt
     1921 tgaaacgact cttacaagac agtggttatc aatatgacat tgaagaggtt cattttggag
     1981 cggtgattgc tactcattta ggagaaggag ccattgcatt tggcgtaaca ccgaggcttt
     2041 aattgtcgat tagaaaaaat agttaattgc aagaatcact aaaacaataa caaaatgtga
     2101 tagaacccaa gtagcctaat cacactttag attgggctac ttggatgata ggttagaaaa
     2161 caacgtatga aattaatgac aatgccttct gagtttcaga aggctttacc catattgact
     2221 aaaataaaag aagctggtta tgaagcctac tttgtgggag gaagcgtcag agatgtttta
     2281 ctcgagcgtc ccattcatga tgtagatatt gcaactagtt cctatcctga agagactaaa
     2341 gcgattttta acagaactgt cgatgttggc attgaacatg gtacagtgct cgtgcttgaa
     2401 aatggcggtg agtatgaaat cacaaccttt aggacagaag atgtctatgt tgactatcgc
     2461 cgtcctagtc aggtttcttt tgtgcgctct ttagaggaag acttaaaacg aagagacttt
     2521 accgtcaatg ccttggcctt ggatgaaaat ggtcaagtta ttgataaatt tagaggactc
     2581 attgatttgg agcaaaaacg gttacgagca gtgggtaaag cagaggaacg ttttgaagaa
     2641 gatgcactac gcattatgag aggctttcga tttgcggcga gtctggattt tgacattgaa
     2701 gctgcaactt ttgaagctat gaggagccat tcacctctat tggaaaagat ttctgtggaa
     2761 cgttctttta ctgaatttga taaattattg atggcaccgc actggcgaaa agggatttct
     2821 gccatgattg cttgtcaggc ttatgactat ttaccaggct tgaagcagca ggaagcaggc
     2881 ttgaatcatc tgatagtttc tttgaaagat aactttacct ttagtgatca ccaccaagct
     2941 tgggcttatg tgatgattag tttagccatt gaggatccta aaagcttcct aaaagcatgg
     3001 aagacttcaa atgattttca gcgttatgtc acaaagttga ttgctcttta tagaattcgt
     3061 caggaaagat cttttgaaaa attggatatt taccagtacg gcaaggaaat ggcaagtcta
     3121 gtggaaggcc tccgaaaagc tcaaagctta tctgttgaca tggaccacat tgaagcttta
     3181 gatcaagcgc tagccattca taacaaatac gatatcgtcc ttaatggttc tcacctgatt
     3241 aaggattttg ggatgaaacc aggtcctcag ctagggctta tgcttgagaa agttgaatta
     3301 gcgattgtag agggacgcct agataatgat ttcactacaa ttgaagcatt tgttagagag
     3361 gaattagcaa catgagccat tttttggtga agaaattgac aaaaacggtg ggagataaaa
     3421 cagtctttca ggatatttcc tttattattc atgactttga ccgtattggg attattgggg
     3481 ttaatggaac aggaaaaaca actcttttag atgtcttgtc gggaaggctt ggttttgacg
     3541 gagaccattc accattttct aaagccaatg attacaaaat cgcttactta acacaagatc
     3601 ctgaatttaa cgatgcatcc tctgttttag atacggtatt gtcatctgat gttaaggcga
     3661 ttcagctgat tcgtcagtat gaactattga tggcgaatta tactgaagat aaacaagaga
     3721 ccttagagtc cctcatgtct gaaatggatc gcttagatgc ttggtctatt gaaagtgatg
     3781 tcaaaacagt cctatcaaaa ttaggcatca cggatttgga acaaaaagtg ggagacctat
     3841 caggtggtat gagaagacgt gtccagttag ctcaagtatt gctaggagct gctgacttac
     3901 tcttgttgga tgagccgacc aaccatctcg atattgacac catcgcttgg ttaacaacct
     3961 atctcaagac agctaaaaaa accgtccttt ttattaccca tgaccgttat ttccttgatc
     4021 atgtggctac ccgtattttt gaattggata aagcgggact gacagaatat caaggcaatt
     4081 accaagacta tgtgcgctta aaagcagaac aagacgaacg agatgctact aatttacaca
     4141 agaagaagca actctataaa caagaattag cttggatgag gacgcagcca caggcgcgtg
     4201 caaccaaaca gcaggctaga atcaatcgtt tcactgactt gaaaaaagaa gttcaccaag
     4261 acagttctgc agataaattg gagatggctt tcgaaacgag ccgaattggg aagaaggtga
     4321 ttcactttga agacctttct tttgcttatg gcgaccgaca gttgattaag gattttaact
     4381 tgattattca aaataaagat cgtattggaa ttgttggaga taacggcgtc ggaaaatcta
     4441 ccctgttaaa tatcatcaac ggtgatctca aaccaacttc tgggaagctt gatattggag
     4501 atactattcg tgtaggttat ttctctcagc agctcaaaga tatggatgag accaaacggg
     4561 tcattaatta ccttcaagaa gtggctgatg aggttaaaac aagcgtggga acaacgagta
     4621 tcagtgagct tttagagcaa tttctttttc cgagatcaag tcatggcacg ctgattgcta
     4681 aattatctgg tggggagaaa aaacggctct acttgctaaa actgctcatt gaaaagccaa
     4741 atgttcttct ccttgatgag ccaacaaatg atttagacat tgccaccttg acggtcttag
     4801 aaaacttttt agctaacttt gcaggaccag tcattacggt tagtcacgat cgttatttcc
     4861 tagacaaagt agccactaag attttagcct ttgaagaagg cgatattcgt attttttatg
     4921 ggagttacag tgattacctt gatgaaaaag cttttgaaaa agaaacagtt gaggctgact
     4981 tagctaaagc aatagtcact gaagaagtgc cacttcctcc gaaagaggag aaaaagcgca
     5041 tgtcctacct tgaaaaacaa gaatgggctc agatagaaga taaaatagca actattgagg
     5101 ctaatattga agaaattgaa aaccaaatgt taactgtagt tagtgattat ggccagttag
     5161 ctcaattaca aaaggaactc gatcagcgca ataatgattt attattggcg tatgaacggt
     5221 ttgagtattt gagtggacta gacatataag tatactatgg taatgttatg tttataataa
     5281 acaagtgata atagaaaaga agtgctcttg cactgagccc caaaagttgg ctactctatt
     5341 tgaagtaaag gatttagttc tgtattgtag aggattaagt ccttttcgtt ttattttgat
     5401 acgtttattg ttgcaataat cgatgataat agtaggtaga acgagtcaat ttagccgttc
     5461 ttaaaagaaa atctaatcag aactcgtctt tgtccattct ttataatggt tttttgtctt
     5521 cttctttgca gagatgcttc tttcaaacgg agttccctcg gtttttttag cgctaaatat
     5581 ctagcttatc ttcatagctt aatgtcatac aaaaacaccc caaacgttag atttttttat
     5641 ctaacgtttg gggtgtagtt tacattatgg cgcttctttt ctattattac gtgaggaaaa
     5701 atcaagtaaa aaagttaagt caactgaaaa acttgacaga aatattcaga aaatttataa
     5761 tactaactat taacaacata tcagctatta aagcatttca aacagcaggt gttttatttg
     5821 gacctgttaa ggctgcaaat gcaagagaaa gcagtatctg gtttgaaaat cttacaaagc
     5881 aataactatc tctcttagac atttgaagaa gcagacagta aattcgataa tattgtgatg
     5941 agaacttagc aacaatctgc tgatgcaggt caatttttat ttggtactca tattgcagaa
     6001 tttcataaag ttgcccaaga tatcttgaaa taaggaatca cctgatgttt taaacagatg
     6061 atactaagtc tatcatatgg tgataatagt ccattgaaca tgtagtttat gaattaaaaa
     6121 gaaggtttaa ggagataaga atgattagag aaatcataac agatcatttt ttattacagc
     6181 aaaaagcgca agtcgccaag aaagaagatc tatggattgg ccaagattta caagatacct
     6241 tagcctttta tagacaggaa tgtcttggga tggctgccaa tatgattggt gaacaaaagc
     6301 gcattgttat tgtgagtatg ggatttattg atttggttat gtttaatcct gtgatggttt
     6361 ctaaaaaggg aatttaccaa actaaagaat cttgtttgtc gttatctggc tatcgcaaaa
     6421 cacagcggta tgataagatt actgttgagt atttggacca taattggcga ccaaagcgat
     6481 taagcttaac aggcttaact gctcaaatat gccagcacga attagatcat ctagaaggta
     6541 ttttaattta acaaaaaacc tagagtagga cgctttaggt tttttttggc aaagatgcct
     6601 gattatataa gggtgatcga ttactagtaa acgctaggat ttcctttttt taataaaagc
     6661 gtttagtcca cctaagctta tcaaggcaag gattgtcata ataggagaca ttttataatt
     6721 gtcccctgtt attggaagag tggaactaga gatagtattt ttgtttgttg ttgtttcttt
     6781 tttgccaagg ctgttattag tgttttcagt agaagtcaaa aggtctgaaa tgatctcact
     6841 agacactata ttgccatcac gatttctaaa aaccttacta atgatactgt gtttaccagc
     6901 actattaact tttgtcgaac tttcaaggtt tgaagttaca taatttttaa ccccttttat
     6961 agtagcatta acagttttac ctgatgcttc taaatttgtg atatatgtga tgaaagcttc
     7021 agtatctgtg ttaatagctc caattaattt agctttttta aatgctgaaa agccatcacc
     7081 accaccataa agaaagtcgt tgacaacaac ggtgtaagta gttgttaagt taatttcttc
     7141 accattgtct ttataaacct taactatctt gaagggggta tcagagttct taggatcatt
     7201 atctgtataa gtgtatgtta aacctgacat ttgaagaaaa taggtctggt tttcatcgta
     7261 ttgctgattt aggacatcgt aaatgtgttg accagtcatt tgaatgactt gaaggatatt
     7321 accaaatggt tgtacagcct gtgcagctcc ccaggtgatg gtccgatcat ttttgacaac
     7381 taggtcactt cgaataccac cattattggt catagcaaag tcaacagttg gaaaagtttt
     7441 cttagcaata gtaagctgag ctgttgttac taagttaccg acaggagatt ctttatcaat
     7501 attttctgtt ttagaaatag ttgaagaatt agttgcagtt ccgatttttc gttcagtaac
     7561 tgttttaaca atatcattag catgatttat tatagctttg atatctgaat tttctgtttt
     7621 gatacctggt gctacagcaa taacatttgc tgatggagtt gtcataaaat cattggtatc
     7681 agtatctagc gtaccacgga catctgcata agcttttcct tgagagagag cttgaacgat
     7741 acgtgtttta ccgatagttc cattagtgta ttgatgatta tgtcctgcaa aaataatatc
     7801 aatgctatgt tcgggataga tttggttcac tttttccata accgtagcca tttcatgatc
     7861 aacaacacca tctttacttg ttgcaggaat atgagctaaa accacaatag catgaacatg
     7921 ttgttcttgt agttctttag catatttggc aatggtttca gctgcatcta aaaattgata
     7981 gtgttcatag ttttgcttta aaacgagatt tggaatctct gtagtcacaa caccaatgaa
     8041 gccaatctta acgattttgt cattaatggc tatgtctttt atagcataag gtttccaacc
     8101 ataggggata tcattggttt ttttatcaat aacattagca atgacgatgg tttgatgcga
     8161 agcttcgtgc tcatattgtt tggtgatatc attaattgtt gattcaggat caggcgcttg
     8221 acctgtcatg atacggttaa attcatctag tccttcgtca aattcatgat taccaagagt
     8281 gccatattca aatttcattt tgttaaagac ttttacagta ggctcatctt gtaaaagtgc
     8341 agagttagca ggacttgctc cgaccatatc tccagcttga acacgtatac ttgttccgtc
     8401 ttgatttgct tgcttgaagt ctatctcagc gtcatccata taagcaccta attgagcagc
     8461 cgtcccagca tttggtattt taccacttgg tgtgtaagct gttccggtat tatcaagagc
     8521 gccgtgaaaa tcattgacgc caaggaattg cacatcaact tgatctgctt gaacgtctgt
     8581 aactaataga gtaaaactag tcaggatact caatacacta ctttttaaaa taaaatattt
     8641 tttcataaaa tctcctaata agttaacgta atcgttatag atcaagttta ctatgttttc
     8701 gtttgtaatt caatggtatt tttaaaaaag aacgcacaaa aaatatatga aagcgattta
     8761 aaaacaa
//
LOCUS       DATWVB010000054         7577 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.054, whole genome shotgun sequence.
ACCESSION   DATWVB010000054 DATWVB010000000
VERSION     DATWVB010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7577
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.054"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..376
                     /locus_tag="VCX65_001573"
     CDS             <1..376
                     /locus_tag="VCX65_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEP5054023.1"
                     /translation="ALSYGITNLFPLYVCFFFFVYISNASKITINIVEKMGIIFVISA
                     IIGATVLAMYLTWTPVGSSTVLGVQSRYLIGIIPLVLLLFSSQQQKFKQIEDILSDKL
                     AIHVSLLFILAMLMSTIFRYYH"
     gene            470..1693
                     /gene="pepT"
                     /locus_tag="VCX65_001574"
     CDS             470..1693
                     /gene="pepT"
                     /locus_tag="VCX65_001574"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEP5054024.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALELAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            1734..2222
                     /locus_tag="VCX65_001575"
     CDS             1734..2222
                     /locus_tag="VCX65_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEP5054025.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHFEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(2209..2406)
                     /locus_tag="VCX65_001576"
     CDS             complement(2209..2406)
                     /locus_tag="VCX65_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEP5054026.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            2455..2931
                     /locus_tag="VCX65_001577"
     CDS             2455..2931
                     /locus_tag="VCX65_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEP5054027.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKASSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            2946..3626
                     /locus_tag="VCX65_001578"
     CDS             2946..3626
                     /locus_tag="VCX65_001578"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEP5054028.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPISFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWV
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    3650..3773
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            3788..4318
                     /gene="infC"
                     /locus_tag="VCX65_001579"
     CDS             3788..4318
                     /gene="infC"
                     /locus_tag="VCX65_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEP5054029.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            4360..4557
                     /gene="rpmI"
                     /locus_tag="VCX65_001580"
     CDS             4360..4557
                     /gene="rpmI"
                     /locus_tag="VCX65_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEP5054030.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            4616..4975
                     /gene="rplT"
                     /locus_tag="VCX65_001581"
     CDS             4616..4975
                     /gene="rplT"
                     /locus_tag="VCX65_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEP5054031.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
     gene            complement(5266..7476)
                     /locus_tag="VCX65_001582"
     CDS             complement(5266..7476)
                     /locus_tag="VCX65_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEP5054032.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIT
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILTQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYENSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNP
                     DEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNPKNKE"
BASE COUNT         2468 a         1234 c         1496 g         2379 t
ORIGIN      
        1 cgcattaagc tatggtataa cgaacctttt cccgctttat gtgtgtttct tcttttttgt
       61 ttatattagt aatgctagta aaataactat taatattgta gaaaaaatgg gtataatctt
      121 tgttatttca gcgattatag gtgcaactgt attagctatg tacctgactt ggacaccagt
      181 agggtcctca actgtcttag gtgttcaaag tcgttatctg ataggaatta tcccattagt
      241 gttgcttctt tttagtagtc aacagcaaaa gttcaaacaa atagaggata tcctttctga
      301 caaactggct attcatgttt cgcttttgtt tattctcgca atgttaatga gtactatttt
      361 tagatattat cattaaactc ttaattagag gctttaaaaa acttagcttg aataagtatt
      421 ttaaagcctt ttatgctata attaaattga gaaattattg aggtggccta tgaagtacga
      481 taacttgtta gatcgattta taaaatatgt caaagtgaat acaagaagcg atccagacag
      541 tgagactact cctagtacgg agagtcaaga agcatttgcc ttaacgattt taaagcctga
      601 aatggaggca attggtttgc aagatgttca ttataatcca gttaatggct atcttattgg
      661 aactctgcct gccaataatc caaccttgac gcgtaaaatt ggttttatag cacatatgga
      721 tacggctgat ttcaatgctg aaaatgttaa tccgcagatt attgacaatt atcaaggagg
      781 ggacattaca cttggcagtt ctaattataa gttggatcca aaagcatttc caaatcttaa
      841 taattatatc ggtcaaacat tgattaccac tgatgggact acacttttag gggcagatga
      901 taaatctggt attgctgaaa tcatgacagc aatagaattc ttaacatcac aaccacaaat
      961 agagcactgt gacattaaag tggcttttgg ccctgatgaa gagattgggg tcggagctga
     1021 taagtttgag gtggctgatt ttgaggtgga ttttgcttat actatggatg gcggtccttt
     1081 aggcgaattg caatatgaaa ctttcagcgc tgcagctcta gaagtgactt ttttaggcag
     1141 aaatgttcat cctggtacgg ctaaggatca aatgattaat gcccttgagt tagcaataga
     1201 ttttcatgag aagctacctg ctaaagagcg acctgaatac acagatggtt atcaaggctt
     1261 ctatcactta accggactaa ctggaacagt tgaagaggca cgcgcatctt acattattcg
     1321 tgattttgaa gaagcatcat ttgaagctag aaaagtgaaa gttgaaaata tagctcaatc
     1381 gatgaatgct cagctaggaa caaaacgtgt cttggtagag cttaatgacc aatactacaa
     1441 tatgaaaaaa gttatcgaaa aagatatgac tgctattgag ttagctaaag aagtaatgga
     1501 agagcttgct atcaagcctg taatcgaacc catacgtgga ggaacagatg gctctaaaat
     1561 ttcatttatg ggtattccca ctcctaatat ttttgcaggg ggtgagaata tgcacgggcg
     1621 ttttgagttt gttagcttac aaacgatgga gagagctgtc gatgtcatta ttggacttgt
     1681 ttgcaaagcc taattatcat gtaattgata tttagtggaa ggggcttata aaaatgatta
     1741 aactatttgg taaaataagg tatcactggc agccagagtt gtcttggtct attatttatt
     1801 ggtctattgc gtttgcacct atttttgtag gtttatcttt gttgtatgag cgcactgaaa
     1861 tacctagtcg ggtttttatt ctatttgcta tttttgctgt cctagttggc attggattac
     1921 atcgttattt cattattgaa aataatggta ttttaagaat cgtatctttt aaattgtttg
     1981 gtccacgtaa gctacttatt tctactatta ctaagattga ggtgaccaaa tcaacacttt
     2041 gtctgcactt tgaagataaa agttatctct tttatatgcg caaatggcct aaaaaatatt
     2101 ttcttgatgc cttagcggtt aatccatact tccaaggaga agttatatta agtgataact
     2161 ttattaaatt agactatttt gaagtttatc agcatgataa aaaagccctt actcgagggt
     2221 aagagcttta gttgggcaag atttgacagc taaaatagcg tccttatctg aaggacaaat
     2281 tgactgactt gtttcagatg agcttgaaaa tgtgacgata ccattgtcat gataatcaaa
     2341 aagtgatgaa taggtttggc atagaccaca agcgatgcat ttttctggaa tgatagatac
     2401 tttcataact attattctaa tatgattttg ttaaattaac aaggggggac gatcatggct
     2461 aaagaaccat gggaagaaaa aattgttgat gatactatag ggacacgaac acgtaaatca
     2521 agaaatgctt tcattagcac gccttggttg actgctttat taagtgtatt ctttgtcatc
     2581 attgttgcta tactttttat tttcttttat acatcaaata gcggtagtaa tagacaagct
     2641 gaaacaaatg gtttttatgg agcatccact cataaaaaaa caaggaaagc ttctaacgct
     2701 aaaaaagcat caagtagttc aacaactaca gacacaacac cttctagcga agaaacactt
     2761 gcttctagtg aaggaactgg cgaaaccctt actgtattgg caggtgaggg ggcagcttct
     2821 attgcagccc gtgcaggtat ttctgtggag cagttacaag cacttaatcc agagcacatg
     2881 actcaaggat attggtatgc caatccagga gatcaagtca ctattaaata attgaagagg
     2941 aaaaaatgaa agcaattaaa attgcgattg atgggccagc ttcaagtgga aaaagtacag
     3001 tagccaagat tattgcaaaa aatcttggct atacttatct agatactggt gctatgtatc
     3061 gctcagcaac ttatatcgca ctgacacatg gctatacggg taaagaagta gcccttattt
     3121 tagaggaact tgagaaaaat cctatttcct ttaaaaaagc aaaagatggc tcccaattag
     3181 tttttcttgg ggatgaggac gtgaccttag ccattaggca aaatgatgtg actaacaatg
     3241 tttcttgggt ctcagctttg ccagaaatta gagaagagct ggttcatcaa caaagacgca
     3301 ttgcacaagc tggtggcatt atcatggatg gtcgtgacat tggaacggtt gttctcccag
     3361 atgcggaact aaaaatcttt ttagtggctt ctgtcgaaga gcgggcagag cgccgctata
     3421 aagaaaacct agaaaaagga attgaatcag attttgagac gctaaaagaa gagattgcag
     3481 ctcgtgatta caaggatagt catcgtaagg tttcacctct aaaagcagct gaagatgccc
     3541 ttatttttga taccacaggt gtttctattg atggcgtggt gcaatttatc caagaaaaag
     3601 cagaaaaaat agttgacatg tcctagagcc tatgttagaa tattaacaat gagaaaagta
     3661 gaagtgagag cttctcgcct tgcgacttag gttgtctggc cctaacatgt caaattccta
     3721 tggaatatta tgtgtgcggg cttgatttat caagtccgct ttcgtttttc tctaaaaaaa
     3781 taaagaggtg aagatcatag ctaaaaagga tctattcatt aatgatgaaa ttcgcgttcg
     3841 cgaagttcgt ctcgttggtc ttgaaggtga acaattaggt attaaaccat tgtctgaagc
     3901 gcaatcattg gctgatgctt caaatgttga tttggtttta atccagccac aagctgttcc
     3961 tcctgttgcc aaacttatgg actatggaaa gttcaaattt gagtatcaaa agaaacagaa
     4021 agaacaacgt aaaaaacaaa gcgttgtgac tgtgaaagaa gttcgtctca gtccagttat
     4081 cgataaaggt gactttgaaa caaaacttcg taacggtcgt aaattccttg aaaaaggaaa
     4141 taaagttaag gtttctattc gtttcaaagg acgtatgatt actcataaag agattggtgc
     4201 caaggtacta gctgactttg ctgaagcgac tcaagatatt gctatcattg agcaacgagc
     4261 aaaaatggat ggacgccaaa tgtttatgca acttgcacca atttcagaca agaagtaatt
     4321 gtcacagttt cattatatct ttaagaggag aatactaaaa tgccaaaaca aaaaacacac
     4381 cgcgcatcag ctaaacgttt taaacgtaca ggttcaggcg gtttgaaacg cttccgcgcc
     4441 tttacatcac accgtttcca cggaaaaact aaaaaacaac gtcgtcatct tcgtaaagct
     4501 ggtttggtta gctcaggaga tttcaaacgt atcaaagcaa tggttactgg tctttaattt
     4561 taaaggcagt agacatttac gagtattata agaattattt gaaggagaac tattaatggc
     4621 acgtgttaaa ggtggcgttg tttcacgcaa acgtcgtaaa cgtattttaa aattagctaa
     4681 aggttactat ggagcaaaac acatcttgtt ccgtactgca aaagagcaag tgatgaactc
     4741 ttactactat gcataccgtg atcgccgtca gaaaaaacgt gatttccgta aactatggat
     4801 cactcgtatc aatgcggctg ctcgtatgaa cggtttgtca tactcacaat tgatgcacgg
     4861 tttgaaactt gctgaaatcg aagtaaaccg taaaatgctt gctgatttag cagtagctga
     4921 tgcagcagct ttcacagctc ttgctgatgc agccaaagca aaacttggca aataagaaac
     4981 gctataccta aaaaataact ttctattacc tatagaaagt tataaagaaa caaaaatgaa
     5041 ggagacgatg gacgtcttct ttttattata ctcaatataa taaaaagcag tttcccatgt
     5101 tttattacca gtaatgtggg atatttagat ggtagcaagg agttttatag ctgatttgtt
     5161 ttctttaggt ctaattagca tattttgatt actgataaac ttgaatatcg ccaataaaaa
     5221 agaagcaaaa ttattatttt gcttctagtc agatcattaa attgattatt ctttattttt
     5281 ggggttatcc tcttttagtt cagaagttgc cgcgtcagct tctacgggat ttagttctaa
     5341 gtaagatggt gctttaaaaa gtttctgagt tgatttatga ccatttttac tgtataaact
     5401 tgttgactct gatccgagtt ttgctgaaat atctttcagt tgttttaact gcttagtgta
     5461 gataaactgg ttaggatcaa tagcttttag accattttga gtatcaaagc gcaggagatc
     5521 acccgtttga atagcgtcgc tagctgctag ttgttgagca acagcagagc gaatttcctt
     5581 agttttggct atagtcattt catcgggatt agtgatttct aaacctgttt gcgtgttgta
     5641 cagacgtcca ctatagttag tgtattcagg agtcatataa gtcccagatg ttcgttgtgc
     5701 cacaatctgg ctattttgag gtgataataa gtcttgtcct aattgaacaa actgactagt
     5761 gtcaatacca agtatgtgga gtaaagtagg aagagcatcg atttcaccgc caaaggtttc
     5821 tttgatacta ccattcgtat aacctggaat atggatcata tacgggactc gttgtagcat
     5881 agcattatca tattcagacc aagtttcaga atctttacca agaagtggag caagactaga
     5941 attacgagaa tttgaaatac cataatgatc accatataaa acaaaaatag aattctcgta
     6001 caaaccagtg gctttcaagt aatcaaaaaa agatttaagg gcagcgtcta aataattggc
     6061 agtagcaaag taaccattga tcgtttcatc gtctgttttg gctaaaggaa aaccttcttc
     6121 actactttcg ccttttagac tagtataagg atagtgatta ctcacagtga taaacttggt
     6181 ataaaaaggt tgttgcatct gttcaagata ttttatggaa tccttaaaca tgtacttatc
     6241 atttaaccca tattgaaaag agttcttact attttgttta gagaagtagc tagaatcaaa
     6301 aaaataatta tagccccatt gtttataagc attattgcga ttccagaaag ttccaacgtt
     6361 accatgaaag acagcgctgg tatagccacc tttttgggtt aaaatacttg gagtagcaaa
     6421 ttgtgtattt tcaccaccgt agttcaccat aaaagaacca ctatttaaac caaataagga
     6481 attctccatc atggtttcag catcagaagt tttacctgct ttaacctgat gaaaaaagtt
     6541 agggaatgct aaggtagcat ttgagtgata aagcgagttg ataaaaggtg ttacctcata
     6601 ttctttatct ccttctttta gtttataatc tattaagaat tgttgaaagc tttctaaatg
     6661 aagaacaata atatttttgc cttttccaat tccaaaatac tgaggatcag gtgctgcata
     6721 atgtcctttg acataagttt taacatcaat taattcttct gcagtagctc catttcgttc
     6781 tttttgagct tgataggttt gattgccgct atagagggta aacgctggta gtcctaaagc
     6841 tctcacaata taagtatttg aaaagccacg tgttaatagt tccggacgat caatttctgc
     6901 taaaaaaaga ttaatagaaa gcaatagact agataaagcg gtgatggcaa atgctgcgcg
     6961 cttgttaaaa ggacgttggt catttttgat ttttttagtg atagataaac taattagaat
     7021 aataaaatca agaatataga taatatccca gatgcgtaaa aggtttaaag cagagtcccc
     7081 taatccagcg gagactttac tactagctag catggcactc actgtaataa agtctgaaaa
     7141 ttctcggtaa tatatagaat ttgatatcaa gagaatgtta aggataatat aaaccaccca
     7201 agaacagata taaaaggctc gggtattctt aacgtaaaga gcaaccccca aaagtaaaaa
     7261 agctagtggg attggattga taatagttag aaagacttgg tatatatttc ccaaatctag
     7321 tgaaaagtct gtatgatatg cccacagggt ctttatccag taacaaaaga gtagagtaat
     7381 tataaaaccc aatcttgtgt tgataaaacc tgtgataagt gttttaaatt tcttcacagt
     7441 agcaacttcc ttatcgtttt ttcctaaaga tgtcatctcc aaataaaatc tcagattaaa
     7501 ttataccaaa aatgtgaagc taatgcttgt tgtaagttca aatttagtag gattttttat
     7561 cagattttgt tataata
//
LOCUS       DATWVB010000055         7519 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.055, whole genome shotgun sequence.
ACCESSION   DATWVB010000055 DATWVB010000000
VERSION     DATWVB010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7519
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.055"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            255..683
                     /gene="lacA"
                     /locus_tag="VCX65_001583"
     CDS             255..683
                     /gene="lacA"
                     /locus_tag="VCX65_001583"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEP5054033.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKYEVVDVSENEVRDFVDTT
                     LAVAKEVNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC"
     gene            718..1233
                     /gene="lacB"
                     /locus_tag="VCX65_001584"
     CDS             718..1233
                     /gene="lacB"
                     /locus_tag="VCX65_001584"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEP5054034.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHEIIDCGTYDNVRTHYPI
                     FGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRAALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            1279..2208
                     /locus_tag="VCX65_001585"
     CDS             1279..2208
                     /locus_tag="VCX65_001585"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEP5054035.1"
                     /translation="MILTVTLNPAIDVSYPLNELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNDFGETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPLLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIKIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFEALKEVLQDELFEGIEWI
                     IVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV"
     gene            2211..3194
                     /gene="lacD"
                     /locus_tag="VCX65_001586"
     CDS             2211..3194
                     /gene="lacD"
                     /locus_tag="VCX65_001586"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEP5054036.1"
                     /translation="MTITLTENKRKSMEKLSIDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSEERFGVDVLKVEVPVNMKFVES
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            3218..3535
                     /locus_tag="VCX65_001587"
     CDS             3218..3535
                     /locus_tag="VCX65_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEP5054037.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            3535..5232
                     /locus_tag="VCX65_001588"
     CDS             3535..5232
                     /locus_tag="VCX65_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEP5054038.1"
                     /translation="MNGLIAQIEKGKPFFEKISRNIYLRAIRDGFIAGMQVILFSSIF
                     ILIAYVPNAWGFHWSKDIENLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFISTMLAAIVGFLLMAANPAKDGGFLTGFMGTKGLLTAFIAAFITVNVYKTCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHTTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKVYDEQILAEEAAGTNSSDALKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKEQMEK"
     gene            5305..6711
                     /gene="lacG"
                     /locus_tag="VCX65_001589"
     CDS             5305..6711
                     /gene="lacG"
                     /locus_tag="VCX65_001589"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEP5054039.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFAALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            7214..7369
                     /locus_tag="VCX65_001590"
     CDS             7214..7369
                     /locus_tag="VCX65_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lantipeptide"
                     /protein_id="HEP5054040.1"
                     /translation="MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
BASE COUNT         2478 a         1201 c         1522 g         2318 t
ORIGIN      
        1 tgtcaaaggg atttatgaaa tgaaaaagaa acacaagaaa cattaggata ataacgtaaa
       61 aatgaaaaaa ataaacatat tttgtttatt ttttataaaa ataaacaaaa aaatgttgac
      121 ttttatgttt ggtgggtgta tgattaggtc atagaaataa tgaaagcgtt atttcaaaag
      181 atgttgcaaa tcgttaatta actatctacg taggttttcc acatttactt attctaaatc
      241 ataggagaaa taaaatggca attattatcg gtgctgacaa agcaggtcaa gaacttaaag
      301 aagttatcaa agattacctt aaagaaggta aatacgaagt cgttgatgtt agtgaaaacg
      361 aagtacgtga ctttgtagat acaactttag ccgttgcaaa agaagttaat gcctccgaag
      421 ataacttagg tattgtcatt gatgcatatg gtgttggttc tttcatggta gctactaaaa
      481 tcaaaggaat ggtggcagct gaagtatcag atgagcgttc agcatacatg acaagaggac
      541 acaacaatgc tcgaatcatc acgcttggtt ctgaaattag tgctccagga attgcaaaga
      601 acattatcaa aggctttgtc gaaggtaaat atgatggtgg acgtcatcaa gttcgtgtcg
      661 acatgcttaa taaaatgtgc taattgattg aaataggtta aaacaaggag aacaaaaatg
      721 aaaattgctg taggttgtga ccatattgtt acttatgaaa aaatcgctgt tgtggattac
      781 ctaaaatcac aaggtcatga aatcattgat tgcggtacat acgataatgt tcgcacacac
      841 tatccaatct ttggtaaaaa agttggtgaa gcagtagcaa gtggtgaagc agaattaggt
      901 gttgttatct gtggtactgg tgttggtatc acaaatgctg taaacaaagt tcccggtatt
      961 cgtgcagcac tcgttagaga tatgacatct gctatctact caaaagaaga gctaaacgca
     1021 aacgttattg gttttggtgg aaaaatcatc ggtggtttgc tgatgaatga tattatcgat
     1081 gctttcttag cggctgaata caaaccaact gaagaaaata aaaaatggat tgaaaaaatg
     1141 gatagcttgc aacatgctag ccaagatcaa aacaacccac acttctttga tgaatttcta
     1201 gaaaaatggg accgtggtga atatcacgac taatatttga aagaattatg ataaggatat
     1261 atagaaaaag gagctattgt gattttaaca gttactttaa atccagctat tgacgtctcc
     1321 taccctttga atgagctaaa atgcgatact gtcaatcgag ttgtagacgt tacaaagaca
     1381 cccggtggta aaggcttgaa tgtttcccga gttctaaatg actttggtga gacagtcaaa
     1441 gctactggtt gtattggtgg agaaagcggt gattttatca ttaatcatct tcctgattcg
     1501 attttaagtc gcttctataa aatttcaggt gataccagaa catgtatagc catattacac
     1561 gaaggtaatc aaactgagat tttagaaaaa ggaccgctgt taagtgtaga tgaaattgat
     1621 ggatttactc atcattttaa atatttactg aatgatgttg acgtagtgac gctctcaggc
     1681 agtttgcctg ctggtatgcc agatgattac tatcagaagt taatcaagat tgccaatctt
     1741 aatggtaaga agactgttct ggattgttct ggaaatgctt tagaagcagt attgaaaggt
     1801 gatagtaaac caacagttat caaacctaat cttgaagaac tttctcaact tctaggtaaa
     1861 gaaatgacaa aagattttga agccttaaaa gaagtcttac aagatgaact atttgaagga
     1921 attgaatgga taatcgtttc tcttggtgct gatggtgtat ttgcaaagca caaggatacg
     1981 ttttataacg ttgacattcc taaaatcaaa attgtaagcg ctgtaggttc gggtgattct
     2041 acagtggcag gtattgcttc aggtttagcg aatgatgaag atgatcgagc tttattaaca
     2101 aaagcaaatg tcttaggtat gttaaatgcg caagaaaaaa caactgggca tgttaacatg
     2161 gcaaattacg ataagttata tcaatctatt aaagtcaaag aggtataaaa atgacaatta
     2221 ctttaactga aaacaaacgt aaaagcatgg aaaaactaag tatagatggt gttatttctg
     2281 ctttagcttt tgaccaacgt ggagctctca aacgtatgat ggctcaacat caaacaaaag
     2341 agccaacagt agaacaaatt gaagagctta aaagtttagt ttctgaagaa ctgacaccat
     2401 ttgcatcatc aattttactt gatcctgaat atggcttgcc agcaagtcgt gttcgttcag
     2461 aagaagcagg cttgttgttg gcatatgaga aaacaggata cgatgcaaca acaactagtc
     2521 gcttacctga ttgcttagat gtttggtctg caaaacgtat taaagaagct ggagcagaag
     2581 cagttaaatt ccttctttac tatgatattg atggagatca agatgttaac gagcagaaaa
     2641 aagcttacat tgaacgtatt ggttctgaat gccgtgcaga agatattcca ttctacttag
     2701 aaattctaac ttatgatgag aaaattgctg acaatgcaag ccctgagttt gcaaaagtta
     2761 aagctcataa agttaatgaa gcaatgaaag tcttctcaga agaacgcttt ggtgttgacg
     2821 tcttgaaagt cgaagttcca gtaaatatga aatttgtaga aagctttgca gatggtgagg
     2881 ttctctttac aaaagaagaa gcagctcaag ctttccgtga ccaagaagct tctactgatt
     2941 taccatatat ttacttgagt gcaggtgttt ctgccaaatt gttccaagat actttggtgt
     3001 ttgcagcaga atcaggtgct aaattcaacg gtgtcttatg tggacgtgct acctgggcag
     3061 gatctgtaaa agtctatatc gaagaaggac cacaagcagc tcgtgaatgg ttgcgtacag
     3121 aaggtttcaa aaatattgac gaattaaaca aagtactaga taaaactgca agtccttgga
     3181 ctgaaaaaat gtaacattat tttcggagga aactacaatg aatagagaag aaactactct
     3241 tttaggtttt gaaatcgtag cctatgctgg tgatgcccgt tcaaaatttt tggaagcgct
     3301 taaagcagcg caagaaggag attatgctaa agcagaagaa ttaatcgctg caggtagtga
     3361 ctgcttgaat gatgctcaca atgctcagac aagtctacta caaaaagaag cagctggaga
     3421 tgacttagct tatagtgtca ctttaatgca tggtcaagat catttaatga cgaccatttt
     3481 attacaagat ttaatgaaac acatgattga actttataag agaggagcaa aataatgaat
     3541 ggattaattg ctcagattga gaaagggaaa cctttcttcg agaaaatttc tcgaaatatc
     3601 tatcttcgcg ctattcgtga tggttttatc gctggtatgc aagttatctt gttttcaagt
     3661 atctttatct tgattgccta tgttccaaat gcatggggct tccattggag taaggatatt
     3721 gagaatctct tgatgacgcc atacaactac tcaatgggta ttttaggttt gtttgtggct
     3781 ggtacgacag ccaaagcttt aactgactca atgaatcgat cattaccaag cacaaaccaa
     3841 atcaacttta tttcaactat gctcgctgct attgtaggtt ttttacttat ggcagccaat
     3901 ccagcaaaag acggtggttt cttaactgga tttatgggaa caaaaggttt gttgacagcc
     3961 ttcatcgcag cttttattac cgtaaatgtc tataaaacct gtgtgaaaaa caatgttact
     4021 attcgcatgc cagaagaggt tccaccaaat atatctcaag tttttaaaga tttgattcca
     4081 tttacgttat cagttgtact gctttatgtg attgaattga ttgttcatac tactttaggc
     4141 gttaacgttg cagaatcaat tggtaaactt cttgcaccat tgttccaagc agcagatggc
     4201 tatgttggaa tcactattat cttcggtgca tttgctttct tctggtttgt tggtattcat
     4261 ggaccatcta ttgttgaacc agccattgca gcgattactt acgcaaatgc tgaaaccaac
     4321 cttcaattac ttcaagctgg tgaacatgct gataagatct tgacttcagg gactcaaatg
     4381 ttcatcgtta ccatgggtgg tactggtgca actctcgtcg ttccattcat gttcatgtgg
     4441 ttaacaaaat caaaacgtaa caaagccatt ggacgtgcat cagttgttcc aacattcttt
     4501 ggtgttaacg aacccatttt gtttggtgcc ccacttgttt tgaacccaat cttctttatt
     4561 ccatttatcc tggcaccgat tgtcaacgta tggattttca aattcttcat tgacacactt
     4621 ggaatgaaca gtttcactgc aaacttacct tggacaacac cagctccatt gggtcttatc
     4681 cttgggacaa acttccaagt gctagcattc attttggcag ctttgttaat tgttgttgat
     4741 gtgattatct actacccatt cttaaaagta tatgatgagc aaattcttgc tgaagaagca
     4801 gcaggtacga attcatcaga tgccctcaaa gaaaaagtag cagcaaactt tgatactaaa
     4861 aaagctgatg ctattcttga aaaatcagca gctaaagaaa ccaaagaaat cactgatcaa
     4921 actaatgttc tcgttctttg tgccggtggt ggtacaagtg gtttgcttgc aaacgctttg
     4981 aataaagcag ctaaagaata tggtgcacct gtcactgcag cagcaggaag ttatggtgct
     5041 caccgtgaga ttttaccaca atatcaactt gttatccttg cacctcaagt agcttctaac
     5101 tatgaagata tgaaagtgga aactgataaa cttgatatta aattagctaa aacagaaggg
     5161 gctcaataca tcaaattgac tcgcgatggt caaggcgcat tagacttcgt taaagaacaa
     5221 atggaaaaat aatatgtcgc tagggaaggt tgggggtact caatcttcct ttatagtgaa
     5281 atgaaaattt agaagaggta tatcatgact aaaacattac ctaaagattt tatttttggt
     5341 ggtgctacag ctgcttacca ggctgaaggc gctacccaca cagatggtaa aggaccagta
     5401 gcttgggata aatacttaga agacaactat tggtacacag ctgagccagc aagtgatttt
     5461 tacaatcgtt atccagtcga tttgaaactt agtgaagaat ttggtgtcaa cggcatccgt
     5521 atctctattg cctggtctcg tatttttcca acaggaaaag gagaagttaa ccctaaagga
     5581 gttgaatact accacaatct ctttgcagag tgtcataagc gtcatgttga gccttttgtt
     5641 acacttcacc attttgatac cccagaagct ctccactcgg atggtgattt cctcaatcgt
     5701 gagaacattg aacattttgt aaattatgca gaattttgtt ttaaagaatt ctcagaagtt
     5761 aactattgga caacatttaa cgaaattggg cctattggtg atggccaata cttggttggt
     5821 aaattccctc caggtatcca atatgatctt gctaaagttt tccaatcaca ccataacatg
     5881 atggtctctc atgctcgtgc agtcaaactc tttaaagata gtggctattc aggtgaaatc
     5941 ggcgtggtcc atgctcttcc aactaagtat ccatttgacg ctaacaatcc tgatgatgtt
     6001 agagcagctg aactggaaga tatcatccat aataaattta ttcttgatgc aacttatcta
     6061 ggtaagtatt cagataaaac aatggaaggt gttaaccata tccttgaggt aaatggtggt
     6121 gaacttgatc ttcgtgagga agattttgct gcactagacg ctgcaaaaga tttgaatgac
     6181 ttccttggta ttaactatta tatgagtgat tggatgcaag cttttgatgg tgagactgaa
     6241 atcattcata atggtaaagg ggaaaaaggc agctctaaat accaaatcaa gggtgttggt
     6301 cgaagaaaag cacccgttga tgttccaaaa acggactggg actggattat cttcccacaa
     6361 ggcttatatg atcaaatcat gcgtgtcaaa gccgattatc ctaactacaa gaaaatttac
     6421 attacagaga atggtcttgg ctacaaagat gagtttgtag ataatactgt ctatgatgat
     6481 ggacgtatcg attatgtgaa aaaacactta gaagttattt ctgatgctat ttctgatggt
     6541 gcaaatgtta aaggatactt tatgtggtca ctgatggatg tcttttcatg gtcaaatggc
     6601 tatgaaaaac gttacggtct cttctatgtc gattttgaaa ctcaagaacg ttatcctaag
     6661 aagagtgcct actggtataa aaaagtagca gaaactcaag tgattgaatg attttgagat
     6721 acttttttaa tacattttta cacttcatgt tcgtttactg aattatagtc acaaaaagta
     6781 gatgatgttg acatttttca agcatagtat tatttgctgt tgatggtaat ccattagttg
     6841 taagatcggg ttataagtgt ttttagttga tgaaaatggg ttttgaaagt tttatttaat
     6901 atcctttttc agatatttga cttctgtcat tcaaactcct gacctgatta aataagtaaa
     6961 gtaaccattt tctgattaga gattgatgtt ataacaagaa gcgattagat tgtaaaatag
     7021 ctgtaaagaa cgagttttgt tttttatatc agagggctat ttgttataaa gtgacctctt
     7081 atgtgacatc tcaaaaatct tactaaaaaa tatgaaaaaa gtcatttttg cactttttac
     7141 tcattgaaaa tgaagacgta ttatttacaa taaaagtgta gaaaatagtc actacatact
     7201 gatagaaagg agaatgagtt ttatgaaaaa ttcaaaggat attttgacta atgctatcga
     7261 agaagtttct gaaaaagaac ttatggaagt agctggtggt aaaaaaggtt ccggttggtt
     7321 tgcaactatt actgatgact gtccgaactc agtattcgtt tgttgttaat taaaacaatc
     7381 tggataagca gactaaaatt tcctgtttag acttagtcta ggcaggattt ttaagtagtg
     7441 gtaggaaaaa atgataaaaa gaaatgaatt aaagttagaa tatcagcaac atcagtttta
     7501 cgaatacttt aactcaatt
//
LOCUS       DATWVB010000056         7517 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.056, whole genome shotgun sequence.
ACCESSION   DATWVB010000056 DATWVB010000000
VERSION     DATWVB010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7517
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.056"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1132
                     /gene="dnaN"
                     /locus_tag="VCX65_001591"
     CDS             <1..1132
                     /gene="dnaN"
                     /locus_tag="VCX65_001591"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEP5054041.1"
                     /translation="QFSINRTLFIHALNATKRAISTKNAIPILSSIKIEVTSTGVTLT
                     GSNGQISIENTIPVSNENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQHQV
                     VLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRPIL
                     TGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVVIPSKSLREFSAVFTDDIE
                     TVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAMERA
                     FLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYLIE
                     SLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRTN"
     gene            1207..1404
                     /locus_tag="VCX65_001592"
     CDS             1207..1404
                     /locus_tag="VCX65_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEP5054042.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVLQP"
     gene            1734..2849
                     /gene="ychF"
                     /locus_tag="VCX65_001593"
     CDS             1734..2849
                     /gene="ychF"
                     /locus_tag="VCX65_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEP5054043.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            2919..3488
                     /locus_tag="VCX65_001594"
     CDS             2919..3488
                     /locus_tag="VCX65_001594"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEP5054044.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            3491..6994
                     /gene="mfd"
                     /locus_tag="VCX65_001595"
     CDS             3491..6994
                     /gene="mfd"
                     /locus_tag="VCX65_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEP5054045.1"
                     /translation="MNILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLGNPKSQGVLIVSLSGLRTLLPNPDVFTKSQIQLTVGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GVFINPASDLIFEASDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYKRLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEREIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQIGSLSKYVSADGKEPKINKLNDGRFQKTKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVSELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYISDERQK
                     IDIYKRIREIQSREDYLNLQDELIDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
     gene            7156..7428
                     /locus_tag="VCX65_001596"
     CDS             7156..7428
                     /locus_tag="VCX65_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEP5054046.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTNIKLN
                     DHIEISFGNKLLTVRVIEIKDSTKKEDALKMYEIISETRITLNEEA"
     gene            7415..>7517
                     /locus_tag="VCX65_001597"
     CDS             7415..>7517
                     /locus_tag="VCX65_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEP5054047.1"
                     /translation="MKKPSIVQLNNHYIKKENLKKKFEEEESQKRNRF"
BASE COUNT         2600 a         1134 c         1438 g         2345 t
ORIGIN      
        1 tcaattttca attaatcgca cattatttat tcatgcttta aatgcaacta aacgtgctat
       61 tagcactaaa aatgccattc ctattctttc atcaataaaa attgaagtca cttctacagg
      121 agtaacttta acagggtcta acggtcaaat atcaattgaa aacactattc ctgtaagtaa
      181 tgaaaatgct ggtttgctaa ttacctctcc aggagctatt ttattagaag ctagtttttt
      241 tattaatatt atttcaagtt tgccagatat tagtataaat gttaaagaaa ttgaacaaca
      301 ccaagttgtt ttaaccagtg gtaaatcaga gattacctta aaaggaaaag atgttgacca
      361 gtatcctcgt ctacaagaag tatcaacaga aaatcctttg attttaaaaa caaaattatt
      421 gaagtctatt attgctgaaa cagcttttgc agccagttta caagaaagtc gtcctatttt
      481 aacaggagtt catattgtat taagcaatca taaagatttt aaagcagtag cgactgactc
      541 tcatcgtatg agccaacgtt taatcacttt ggacaatact tcagcagatt ttgatgtggt
      601 tattccaagt aaatctttga gagaattttc agcagtattt acagatgata ttgagaccgt
      661 tgaggtattt ttctcaccaa gccaaatctt gttcagaagt gaacacattt ctttttatac
      721 acgcctctta gaaggaaatt atcccgatac agatcgttta ttaatgacag aatttgagac
      781 ggaggttgtt ttcaataccc aatcccttcg ccacgctatg gaacgtgcct tcttgatttc
      841 taatgctact caaaatggta ctgttaagct tgagattact caaaatcata tttcagctca
      901 tgttaactca cctgaggttg gtaaggtaaa cgaggattta gatattgtta gtcagtctgg
      961 tagtgattta actatcagct tcaatccaac ttaccttatt gagtctttaa aagctattaa
     1021 aagtgaaaca gtaaaaattc atttcttatc accagttcga ccattcaccc taacaccagg
     1081 cgatgaggaa gaaagtttta tccaattaat tacaccagta cgaacaaact aagtaagaaa
     1141 aagctccctt ttaggagttt ttttgttatt ataaatatta acgataatat aagtggagaa
     1201 aagggaatgt atcaaattgg atcatttgtt gaaatgaaaa aacctcatgc ttgtgtaatt
     1261 aaagaaactg gtaaaaaggc taatcaatgg aaggtactga gagtaggagc tgatattaaa
     1321 attcagtgta ctaactgtca gcatgtgatt atgatgagtc gttatgattt tgagcgaaaa
     1381 ttaaaaaaag tactgcaacc atgaaagtcc ttttaaataa ataattctag ctatatttgc
     1441 aaccaatact ttcctaaaaa attgctagta tgccgttgga aaattagcta ttctaatgtt
     1501 atcgaaagaa gaaagatggc cattgacaat gacgaaagtt gtagcacagt tacttagttt
     1561 ctcggcaaac tatatcaaaa tgagaataat acaccaaact ttgataattt aaatgaaggt
     1621 gaaagagtgg cataatgata agcaaatctg aaattttctt cttattcata ccgctttttc
     1681 ttctattttt tggtataata atcttgattg aaatttgaat ggagattcgc taaatggctt
     1741 taacagcagg tattgtaggc ttaccaaatg ttggtaaatc aaccttattt aacgcaatta
     1801 caaaagcagg agcagaagct gctaattatc cttttgcgac tattgatccc aatgttggta
     1861 tggtagaggt tccagatgag cgtctgcaaa aattgacaga attgattaca cctaaaaaaa
     1921 cagttccgac aacctttgaa tttactgata ttgcaggtat cgttaaaggt gcttctagag
     1981 gggaaggtct aggaaataaa tttttagcta atattcgtga agtcgatgct attgttcatg
     2041 tggtacgtgc ttttgatgat gaaaatgtca tgcgtgaaca aggtcgtgag gatgctttcg
     2101 ttgatcctat agcagatatt gacactatta atcttgaatt aatcttagct gatttagagt
     2161 caatcaataa acgttatgcg cgtgttgaaa aaatggcacg aactcaaaaa gataaagaat
     2221 cagtagcaga gtttaatgtt ttgcaaaaga ttaaacctgt tttggaagat gggaaatcag
     2281 ctaggacaat tgagtttaca gaagatgaag caaaagttgt taaaggtctc tttttattaa
     2341 caactaaacc tgttttatat gtagctaatg tcgatgaaga taaagttgct aatccagatg
     2401 gtattgatta tgtcaaacaa attcgtgact ttgcagctac tgaaaatgct gaagtagttg
     2461 ttatctcagc gcgtgcagaa gaagaaattt cagagcttga cgatgaggat aaagaagaat
     2521 ttttggaagc tatcggtctt actgaatcag gcgttgataa attaaccaga gcagcttatc
     2581 atctcttagg ccttggaacc tattttacag caggtgaaaa agaggttcgt gcttggacgt
     2641 ttaagcgtgg tataaaagct ccacaagctg ctggtattat ccattcagat tttgaaagag
     2701 gttttattcg tgcagtaacc atgtcttatg atgatctaat gacctacggt tcagaaaaag
     2761 ccgtcaaaga agctggacgc ttgcgtgaag aaggaaaaga atatgttgtc caagatgggg
     2821 acatcatgga attcagattt aatgtgtaat tatattaaaa caatatcaga aggttggaag
     2881 aacattccag cccttttggc attttagaaa gagaaaatat ggtaaaaatg attgttggtc
     2941 tgggaaatcc aggctctaaa tatgaaaaaa caaagcacaa tattggtttt atggctattg
     3001 acaatattgt caagaacctt gacgttacct ttacagatga taaaaatttt aaagcacaga
     3061 taggaagtac ttttattaat catgaaaaag tttactttgt gaaacctact acttttatga
     3121 ataatagcgg catagcagta aaagcattac taacctacta taatattgac ataacagatt
     3181 taattgttat ctatgatgat ttagacatgg aagtcagtaa attacgttta cgtagtaagg
     3241 gttcagcagg aggacataat ggcattaagt caatcattgc ccacattgga actcaggaat
     3301 ttaaccgaat caaagttggt attggacgac ctttaaaagg tatgactgtt attaaccatg
     3361 tgatgggcca attcaatacc gaagataata ttgctatttc gttaactctt gacagagttg
     3421 tcaatgctgt caagttttat ttacaagaaa atgattttga aaaaacaatg cagaaattta
     3481 atggataatc atgaatattt tagaattatt tagtcagaat aagaaagtcc aatcctggca
     3541 ctctggatta accaccttag gaagacaact ggtaatgggg ttatcgggtt caagtaaagc
     3601 attggctata gcttccgctt atttagatga tcaaaaaaaa atagttgtgg ttacatcaac
     3661 tcaaaatgag gttgaaaaat tagccagcga tttatctagt ttacttgatg aagaacttgt
     3721 tttccaattt tttgcagacg atgtggctgc agcggaattt atctttgcgt caatggataa
     3781 agctctatca agaatagaaa ccctgcaatt tttagggaat cctaaatctc agggcgtttt
     3841 aattgttagt ttatcaggct taagaacttt attgccaaac ccagatgttt ttacaaagag
     3901 tcagattcaa ctaacagttg gagaagatta tgatagtgat actcttacta aacaactgat
     3961 gacaattggc tatcagaagg tctcacaggt cattagtccg ggagaattta gccgtcgagg
     4021 ggatatttta gatatctatg agattacaca agaattgcct tatcgattgg aattttttgg
     4081 cgatgatatt gatagtatta ggcaatttca tccagaaact caaaaatctt ttgaacaact
     4141 agaaggtgtt tttattaatc cagcaagtga tcttattttt gaggctagtg attttcaacg
     4201 tggcattgag caattagaaa aggctctaca aacagcacaa gatgataaaa aatcttattt
     4261 agaagatgta ttagctgttt caaaaaacgg ttttaaacat aaggatatcc gtaaatttca
     4321 atcattattt tacgaaaaag agtggtcatt attagattat attcctaagg gaacgccaat
     4381 cttttttgat gattttcaaa aactagttga taaaaatgca agatttgatt tagagattgc
     4441 taatctcttg acagaagatt tacagcaagg aaaggctctt tccaatctta actactttgc
     4501 agataattat cgagagctta ggcactataa gccagcgacc ttcttttcaa attttcataa
     4561 gggacttgga aatatcaaat ttgatcagat gcatcagcta actcagtatg ccatgcagga
     4621 attttttaat caatttcctt tgttgattga tgagattaaa cggtatcaaa aaaatcaaac
     4681 aacggttatt gtacaggtag agtctcagta tgcttacaaa cgacttgaaa aatcttttca
     4741 agattaccaa tttcgccttc ctttagtgag tgctaatcaa attgtttcac gtgaatcaca
     4801 aattgtaatt ggagctatct ccagtggttt ttattttgct gatgaaaagt tagcgttaat
     4861 cacagagcgt gaaatttatc ataaaaagat caaacgacgc gctagacgat ctaatattag
     4921 caatgctgag cgtttgaaag attacaatga gttagcagta ggtgattacg tggttcataa
     4981 tgtccatggt atcggtcgct ttcttggaat tgaaacgatt cagattcagg gaatccatcg
     5041 agattatgtt actattcaat atcaaaattc agaccgtatt tctcttccaa ttgaccaaat
     5101 tggtagctta tcaaagtacg tttctgctga tggaaaagaa cctaaaatta ataaactcaa
     5161 tgatggtcgt ttccaaaaga caaagcaaaa ggtcgctaga caagtagagg atattgctga
     5221 tgaccttcta aaattatatg ctgaaagaag tcagcaaaaa ggattttcat tttcaccaga
     5281 tgatgacttg cagcgcgctt ttgatgatga ttttgctttt gtagaaacag aagatcaact
     5341 taggtctata aaggaaatta aagctgatat ggagagcatg cagcctatgg atcgtctttt
     5401 agtaggcgat gtaggatttg gtaagacaga agtagctatg agggcagcct ttaaagcggt
     5461 gaacgatcac aaacaagtag ctgtcttagt tccaaccaca gtcttggccc agcagcatta
     5521 tgaaaacttc aaagcacgct ttgaaaatta ccctgttgag gttgacgtct taagtcgttt
     5581 ccgtagtaaa aaagagcaag ctgaaacact agaacgtgta cgaaaaggtc aaattgacat
     5641 tattatcgga acccatcgac tcctatcaaa agatgtggtc ttttctgatt taggattgat
     5701 tgtgattgat gaggaacaac ggtttggtgt taagcataaa gaaactttaa aggaattaaa
     5761 aactaaggtt gacgtcttaa ccttaacagc tactccgatt cctagaacct tacacatgtc
     5821 tatgttaggt atccgagatt tatcggttat tgagacccca ccaaccaatc gttatcctgt
     5881 tcaaacctat gttttggaaa ataatccagg tctcgttaga gaagctatca ttcgtgaaat
     5941 ggatcgtgga ggacaaattt tttacgttta caataaagtt gacactattg aaaagaaagt
     6001 ttcagagcta caagaattag tcccagaagc ttctataggt tttgttcatg ggcaaatgag
     6061 tgaaattcaa cttgaaaata ccttgattga ctttataaat ggtgattatg atgtccttgt
     6121 ggctacaaca atcatcgaaa caggagttga catttctaat gtaaacactt tgtttattga
     6181 gaatgctgat catatgggat tgtcaacttt atatcaacta cgagggcgcg tcggaagaag
     6241 taatcgtatt gcttatgctt acctgatgta tcgtcctgat aaggtcctaa cagaggtttc
     6301 tgaaaagcgt ttagaggcta ttaaaggctt tactgaatta ggttcaggct tcaagattgc
     6361 tatgcgagat ttgtctatac gaggagcagg taatatttta ggggcttctc agagtggctt
     6421 tattgattcg gtcggttttg aaatgtattc tcagttattg gaacaggcta ttgctagcaa
     6481 gcaaggaaaa acgactgttc gccaaaaagg taatactgaa atcaatcttc agattgacgc
     6541 ctatttgcca gatgattaca tatcagatga gcgtcaaaaa attgacattt acaagcgtat
     6601 tcgagaaatt caatcaagag aagattatct caatttgcag gatgagctga tagatcgttt
     6661 tggagagtat cctgatcaag ttgcctattt gttagagata gctctgctaa aacattatat
     6721 ggacaatgcc tttgcggaat tagttgaacg caaaaataat caggtcattg ttcgatttga
     6781 agtaacttct ttaacttatt tcttgactca ggattatttc gaagccttat cgaaaaccca
     6841 tcttaaagct aaaattagtg aacatcaggg gaaaatcgat atcgtctttg acgttcgcca
     6901 tcaaaaagat tatagaattt tagaagaatt gatgttattt ggagaaaggc ttagtgagat
     6961 aaaaatcaga aaaaacaatt cagtttttaa ataataattt gaaacaactt ttagactgaa
     7021 tagtattaat gacaatggaa cgaactagct ctttatactt ttgtcaaaaa tctaagatct
     7081 ttgctgcgaa attaggatct tttctaccat ttaaaaaata aaaatgataa aatgaagagg
     7141 attgtaggag aaattatgag actagataaa tatctaaagg tatcgcgcct tattaaacgt
     7201 cgttcagtag caaaagaagt tgcggataag ggacgaatta aagttaatgg gatacttgct
     7261 aaaagttcaa cgaatataaa actaaatgat cacattgaaa ttagttttgg aaataaatta
     7321 ctgacagtaa gagtcattga aataaaagat agtacaaaaa aagaagatgc tcttaagatg
     7381 tatgagataa tcagtgaaac aaggataaca ttaaatgaag aagcctagta ttgttcaatt
     7441 aaataatcat tatattaaga aagagaatct caaaaaaaaa tttgaagaag aagaatctca
     7501 aaaaagaaat cgtttta
//
LOCUS       DATWVB010000057         7231 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.057, whole genome shotgun sequence.
ACCESSION   DATWVB010000057 DATWVB010000000
VERSION     DATWVB010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7231
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.057"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            584..673
                     /locus_tag="VCX65_001598"
     CDS             584..673
                     /locus_tag="VCX65_001598"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP5054048.1"
                     /translation="MIIDYCNNKRIKIKRKGLSPLQYKTKSFT"
     gene            complement(711..1634)
                     /locus_tag="VCX65_001599"
     CDS             complement(711..1634)
                     /locus_tag="VCX65_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5054049.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1627..2697)
                     /locus_tag="VCX65_001600"
     CDS             complement(1627..2697)
                     /locus_tag="VCX65_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5054050.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2706..3632)
                     /locus_tag="VCX65_001601"
     CDS             complement(2706..3632)
                     /locus_tag="VCX65_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5054051.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3632..5134)
                     /locus_tag="VCX65_001602"
     CDS             complement(3632..5134)
                     /locus_tag="VCX65_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5054052.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYEKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTATMTFMLALPSIAVI
                     YVVRFLGGMAGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5199..7169)
                     /locus_tag="VCX65_001603"
     CDS             complement(5199..7169)
                     /locus_tag="VCX65_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP5054053.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTVGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKVEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDSAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     AKQYENAKEKWMKAKAKSNAKYAEKLADHVEK"
BASE COUNT         2248 a         1404 c         1344 g         2235 t
ORIGIN      
        1 ctttttttgt acttttttat ttgcccgcgt tgtaaaatga agtgcaacaa aaaagagaaa
       61 aagccttgaa ctacacccca aacgttagac aaaaaaatct aacgttcggg gtatttttta
      121 tgaaattaag tgatgaaagt acgaaataga catcgttaag aaagaaaaaa atacctacta
      181 tccaccagag ataaagcaag aaataatgga taacgttttg atagaaggcc cgccacaata
      241 ccaagtatca cttgtttatg gcttgttaca tgcaggaact ctcccaagtt gaatagtaca
      301 atataagaaa aacagttata ctgttgagaa aacaagagca agaccatcac aaacaggacg
      361 taaaccaaaa gaaacctgaa gaaatgacta aattagagcg gcttcaagaa gaaaatgaat
      421 atctcagaac tgaggttgct tacttaaaaa aaccgaggaa ctccgtttga aagaagcatc
      481 tctgtaaaga agaagacaaa aaaaccatta taaaaaatgg acaaagacga gttctgatta
      541 gattttcttt taagaacggc tgtattgact cgttctacct accattatca tcgattattg
      601 caacaataaa cgtatcaaaa taaaacgaaa aggacttagt cctctacaat acaaaactaa
      661 atcctttact taaaatagag tagccaactt ttggggtcag tgcatctctt ttacaattct
      721 ttttgatatt tttcaatttc tgcttggttt gcccaaacaa agtgatttgg tttgatttca
      781 accattgatg gcttatctaa tgtataatca tgttggtctg gatgatagac aacaagttct
      841 ttttgacgct ctaaaattgg atctgggata ggcacggctg ataacaaaga ttgggtgtag
      901 ggatgaattg ggttattaaa cagttcttct gtttctgcaa cttctacaat aaccccttta
      961 tggataaccg caatacgatc tgaaataaag cgaacgactg aaagatcatg ggcaatgaag
     1021 agataagtca aacctttttc ggcttgcatc cgtttgagaa ggtttaaaac ctgtgcgcga
     1081 acggaaacgt ccaaagctga aatcggttca tcagcaataa cgaattcagg gttcattact
     1141 agggctctag cgataccgat ccgctgacgt tgacctcctg aaaattcatg agggtagcgc
     1201 gtcaaatgct ctgatagcaa accaacttcg gccatcatgt tcttaatttt ttctttacgt
     1261 tcttcctctg ttttaaacag attaaagtta taaagacctt ctgaaatgat gtagtcaacg
     1321 gttgcccgtt cattcaaact agcagcggga tcttggaaaa tcatttgaat tttacgaatg
     1381 agctcattgg cttctgattt tgattttctg ccattaatta ctttcccatc gtataaaatt
     1441 tgacctgagc tagtatcgtt caaaccaata atagcacgac caattgttgt tttaccactc
     1501 ccagattctc caactaaaga aaaggtttct ccttttttaa taaagaaatt agcattttta
     1561 actgcaacaa attttttctt tccttctccg aaggaaattt ctaggtcttt tacttcgact
     1621 aatttctcag acatttcctt cctcctgttg tgacattttc cttaagattt tttgatgcaa
     1681 atcttgaatg acttctggtt tttgaacttt tggagcctct gggtgtaaaa gccatgtttt
     1741 ggcccaatga gtctcagata cgttaatcgc cggaggtgct ttttcaaagt ctaaaaccat
     1801 agcatattct gagcgaagtg caaaggcatc tccgataatt ggtgaataaa gtgatggagg
     1861 cgttcctgga atagcgtaaa gttcaccaga ttcatctgcc aactgcggta agctagacag
     1921 caaactccat gtataggggt gccttggatc atagaaaatc tcttcgactg ttccaaattc
     1981 aacaatttct cctgcataca tgacagccac tttatctgca atgcttgcca caacacctaa
     2041 atcgtgcgta ataaagataa tggtgaaatg atattctcgt tgaagcgact tcaataactc
     2101 aacgatttga gcttgaatag tcacatcaag ggctgttgtt ggctcatcac agataagaat
     2161 atctgggcga caagctaaag caatagcgat aacaatacgt tgacgcattc ctcctgaata
     2221 ctcaaatggg taatcttcaa agcgtttttt ggcatttggg atacccactt tattcatgta
     2281 atcaagggcc atttctttag ctttggcatg acttactttt tggtgcttaa taatcacttc
     2341 tgtgatttgg ctaccaatag ttttaatggg actaagactg gtcattgggt cttggaaaat
     2401 cgttgcgatt tttgagccgc gaatctttgc ccactcttta tttgttttta aatctgtcaa
     2461 ttcttgccca cgatagacaa ttgaaccatt agcaatgcgt ccattagact ccaacatccc
     2521 tgtaaaggtc tttgttaaaa cagatttacc tgagcctgat tcccctacaa aagcaaggac
     2581 ttctccttca acaagttcca gtgagacgtt acggatagct gttaaaacac gatcacgcac
     2641 atcaaattct accaccacat ctttggcagt taagattaca ttattttctt ttgtcatttt
     2701 aactcctatc tatgtgaacg tgggtcactg gcatcagcca agttttgtcc gacaatgtat
     2761 agtggtaacg atactaaaat caatgttact aagggaatcc aaaagaggta ggcatttgtt
     2821 gttaagttgc ttgaataatt agcaatcaaa cgtcctaaac ttggagtggt ggttggtaaa
     2881 ccaatcccaa agaaggataa gaaggcctca gaagatacat aaactggtag catttgtgac
     2941 aacatagtca tgataactga aaccaattga ggcaggaggt tcttaacagc aatcttgtac
     3001 attggtgttc ccaaagtttg actagcaagg ttgtattcta aatcacggta acgcaagatt
     3061 tgaacacgga tggagtaggc gacaccaatc catccagtga tacagaaagc tagaatcaaa
     3121 ttccaaaatc ctgcacctaa tgaataggtc aaaacaatga taataagcat agaagggata
     3181 tttgagataa tgttataaat ttcaatcata actttatcaa atgctttaga aactccccat
     3241 atggctccta acactacccc aatggtgata ttaattagtg tcgctataac tgagattaaa
     3301 atagaattac gtgccccata ccaaacacca tcaaacagag attgcccatt tttgtcggtt
     3361 ccaaaccagt actctgcatt tggccaaata taacgctttg aaaagtcatt gatattacta
     3421 acgtcattaa agtcgtagtt ggcaaacatt ggataaataa agctcatcat caagactgtc
     3481 actaaaatca cgagcataaa gactgtagat tttttagaaa aaaactgacg aaacactgat
     3541 ttccagtaag aataagcagg ggtatcaatc acttcggagg cttcactatc gcgctcaaca
     3601 aatcgaaatt tagatttatc aatcgattcc attacttacc tccttttttt gttgacaatt
     3661 taatacgtgg atcgacaagg gtcatgacaa tatctcctag taaaagtgaa acaattgaca
     3721 agacagtgaa gataaaggtt aatccaacaa tcatagaatt gttagcagat ttaatagaat
     3781 caattaacat tttacccata cccgggaagg caaagacagt ctctgttaag gttgcaccac
     3841 caatagcaag gataatactt gcaggaaccc ctgacacaat tgggaccatg gcatttttga
     3901 agagatgccc tctgtaaatt tcagattctg ataatccttt tgaacgcgca aaacgtaccc
     3961 aatcactggc ctgaaggtca acaagatagc gacggaacca gataaccgta gttggaatat
     4021 ttaaaattcc taaaataagg gctggtaaaa tataagattt aggatcagat gcccctagca
     4081 ttgggaaact atctggtaaa ccagccatgc cacctaggaa gcgaacaaca tagataacag
     4141 caatacttgg taaagcaagc atgaaggtca tggtcgctgt tgagaaacgg tcaaaatagg
     4201 tatttttaaa ccgagccata aataaaccaa gaggcaagcc aacgatatag gaaaacataa
     4261 caccaaaaaa accaattaca aaagaattgt gaatcattga tgggtcgaca taattattga
     4321 tggttttagt gtaggaatct cccttaccat agtttacctt ggtgatatca tccaatgatt
     4381 ttggattttt gtagctacgg ctatagatat ccactgacga tttcttagtg acacctgatg
     4441 ggaaggtcac atcttgaaga gctgttcgtc cttgcccttg tgaaataacc tgaagaacag
     4501 gaatattgct gtatgttggg taagatgttc ctaagtttag ggtaacaaag ttttggtgaa
     4561 gataaggaaa ttttccgtta gtgtagagga gatatttatg ttttgtcccc gaaccaacaa
     4621 gtgaccagcc aactgattta tctttttcta gacgaatata cctagctaat tttggattgt
     4681 ctttatcctg aatcttccaa gggtgatcaa taacaactag atttgagaaa aagttccaaa
     4741 cacgttcgta aataggaata ttgcgaattg cataaaactg tttgctagtg gggaagcgtt
     4801 ttagctgcca gccattgcca agagaatcaa tatacttctc atagatagct ttgttagcac
     4861 tagttgcttc tgtcgttaca ctactatcta ctttagaagc attatctttt aattctttgc
     4921 ttgaaaaata attgacataa cccatacgtt gaaaagttag attttcatac gctacttttt
     4981 tatctggtgt tgttgtcatt ttattataat tagggtcttg tttaaagata aggctggtag
     5041 gtactagagt atatacgatg gtgtatgtta aagccgttac caaaactacc gacactaacg
     5101 atcgcatgat acggtttaaa atgtattttt tcatagttat cctcaatagt tcaaaagaac
     5161 ttcctcacat aaacgagaaa gttcttttga acatcgtttt atttttcaac gtgatcagct
     5221 aacttctcag catattttgc atttgactta gcctttgctt tcatccattt ttcttttgca
     5281 ttttcgtatt gttttgctgt gacaggtttg tcttgaagtt tcattccttt atatgctaga
     5341 ggacctttag accctgccca agagaagccc ccgctaaatg gaacggcttt agtaactcgt
     5401 ggagtgccac ccaatgccac aactggaata tctacggcac tatctgtaag gtaggcttgt
     5461 gcttttgcgt aagctttata gcgcgcatcg ttgtcgtctg taattgctgc tgcttcatca
     5521 aggagagttt ggtaagtatc aaggcctgca gctgccacaa catccttatt ttgacctgct
     5581 ttgattccaa gtttttggat aacagatcca ccacctactg gactcatgat gtcaaggtag
     5641 gtccgtggat cttggtagtc tggtccccac catgatgaaa tgatatcgta gtcttgttgt
     5701 tctggggtct cagcatagaa gccttgggct tcgtgagttg atgtttctgt ttcaagaaca
     5761 ttgacaatga cattttcttt accaagagat gcttcaacag attgtttgaa agactgggct
     5821 tcctgaacag ttgctgcgtt tgcctggtca acagggtaat ctaattgaac tgggaaggtt
     5881 acaccttcag ctgtcaaagc ttctttggct tttgcaaatt caacttttgc tttttcagga
     5941 ttatagaaac catcttgagc atcagctaag ttaacgtctt tccattcatc accaagtttt
     6001 gccatttcct tttcaacttc tgaaccaaaa tcactttctc caacggttac aaaagttggt
     6061 ggcacaagca tgttacgtaa ggcttttgtt ttggcatctt gacctgcagt ttgtgcttgg
     6121 aatgacgctc ggtcaaaagc aaactgaata gcttgacgaa aatccttgtt gttaagagct
     6181 ttcttaccgg catcttgttg tgcagggtct ttcttagtgt ttttgaaaga agtacggttc
     6241 aaattccatg ttaaatgacg gatatctcca gtcaacattc cgtaagtaat attatcagca
     6301 tagtttttct tagctgattt gtaggtaggg tcatttgggt aaagtcgtgc aacgctgaac
     6361 tcacccttgt caaagttctt gtagaacgaa cctgggtctg aaccatctga gtaagtcaat
     6421 ttaacagatt ctatcccaac attcttagca tcccagtagt tttcattttt atggaattcc
     6481 atagatgatt ttgaggtgaa ggcgctcaag aagtaagcac cattaacaag gattgatgat
     6541 ggatcggttg taccaaaatc tttacctttt gacttcaaaa atttcgcatt aactgggaaa
     6601 agcacactat aagttgtttt tgaattccag tagctttcag gcttgttcaa agtatactga
     6661 acagttttat cgtcaagggc tttgacacca acttctttaa aatctacttc accattttgg
     6721 taagccttta agttttttat tgaatcttca acaacgtaaa gagcatctga tttatcgtca
     6781 accgcgtgct tcaaaccagt cacaaaatct tctgctgtta ctggggcata ttcttcacca
     6841 tcagccgtat accaagagac accatcgcga agagtataag tataagtcag accgtctttt
     6901 gaaaccttcc aatctttagc aagtgatggt actaaattac catactcatc gttttccaaa
     6961 agaccatcaa ccatttgtgt tatcacatca gtcgttccac cgccattagt caaaatataa
     7021 tccaatgatt ttggatcgtt aacaaaaacg tacttgtagg tttttgtagc ttctgagcca
     7081 cctgaagcat ttttattacc acaagctgcc aaagcggata ctgacaagat cgcaacactt
     7141 acagctgcca accatttact tttcttcata aaagtcaccc ctaaacttta tttttcattt
     7201 tttggcaatt gctaaatgaa attggttaat t
//
LOCUS       DATWVB010000058         7037 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.058, whole genome shotgun sequence.
ACCESSION   DATWVB010000058 DATWVB010000000
VERSION     DATWVB010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7037
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.058"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(118..1377)
                     /locus_tag="VCX65_001604"
     CDS             complement(118..1377)
                     /locus_tag="VCX65_001604"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEP5054054.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
     gene            complement(1551..2747)
                     /locus_tag="VCX65_001605"
     CDS             complement(1551..2747)
                     /locus_tag="VCX65_001605"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEP5054055.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTKAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            complement(3283..5661)
                     /locus_tag="VCX65_001606"
     CDS             complement(3283..5661)
                     /locus_tag="VCX65_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEP5054056.1"
                     /translation="MKTKKVIILVGLLLSSQLTLISCQSRGNGTYPIKTKQSRKGMTS
                     NKIKPIKKSKKTNKTHKGMAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTATANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAYVADQYDPAKKAEKPAETPHTP
                     ELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIG
                     KDIPEPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTSFPSNEKDPNKM
                     KEWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKRLLMT
                     KTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLP
                     NLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVD
                     LATLQAPNLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEA
                     EGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPN
                     KTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAK
                     ESAQEASESHDYNHNHAYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            5865..6806
                     /locus_tag="VCX65_001607"
     CDS             5865..6806
                     /locus_tag="VCX65_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEP5054057.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFTENSQEK
                     RAIAIDLTDQGHLIVQFENGDFQTLRSGEISLSSWEN"
     gene            complement(6781..6984)
                     /locus_tag="VCX65_001608"
     CDS             complement(6781..6984)
                     /locus_tag="VCX65_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEP5054058.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKTANSPKKKD"
BASE COUNT         2087 a         1497 c         1254 g         2199 t
ORIGIN      
        1 atatcatttt tatatttttt atgacagtta aaaagccata aaatgcaaca aagtatgcac
       61 ctaagtatta ttagcctaag cacatgtaat ataaaaaaga gaagcgttag cttctcttta
      121 gtcttcgatt aattgaatat ctgcccctag tgctgttaat tttgcaatga tactagcata
      181 gccacgtaag ataaattcaa tattagtaat ttctgtcttg ccttcagcta ttagaccagc
      241 agtcactaga gccgctccgg cacgtaaatc agtggctttg acctgagctc ctgtcaggcg
      301 agacggccct tgataaacaa tctgaccacc aataactgag atatctgctc ccatgcgcat
      361 caactctggc acatggttaa tgcgcttttc atatatagtg tcaataatcg ttccacgacc
      421 atctgctttt aacaacaagg gcgttaatgg ctgttgcaaa tcagtggcaa aaccagggta
      481 aggagaggtt ttaattgtaa tagccttgag ggattcttgc ttttcaacaa agatagcatc
      541 ctcttctacc gtcatacgga cacccatttc ttctaactta gcaatgaaac tctctaaatg
      601 ctcataaaga acattagtga tcttaacacc ttttccaata gctgccgcca aagcgatata
      661 agtccctgct tcaatacgat caggaataac ttggtgtcta gtaccatgca atttctgaac
      721 accttgtatc gtaataatat ctgtacctgc tccacgaata tgcgcaccca tgttattcaa
      781 aagagtagcc acatcaataa tctctggctc acgtgcagcg ttttcaataa ccgttttacc
      841 ttgagctttt gttgccgcaa ccatagtatt aattgtagca ccgacactaa cggtgtccat
      901 atagatatga gcgccatgaa ttttttgacc atttgtcgat aaattcatat tttcaccctc
      961 ataagacact tcaactccca tagcctcgaa ggccttcaaa tgcaagtcaa ttggtcttgg
     1021 tcctaaatcg caaccaccag gtaagccaac aactgcttgt ccaaaacgac ctaaaagact
     1081 accgtagaaa taataggaag ctcgaagact attaatcttt ccgtaaggca tcgggatgtc
     1141 ttgcacccct ctagggtcaa tttctaaagt atcaccatga tagtttactg ttgctcccat
     1201 aagctccatg atttcaatca gactatctac atcactaata gcaggtacac catcaagaat
     1261 cacaatatca tcggctaaga tgattgctgg aataagcgca acaacactgt tttttgcccc
     1321 tgaaactgcc acttctccag ataaggcttt tccgccatta ataataattt tacgcataca
     1381 ttcaaaactt tcttatacta gaattcaacc ttttcatttt atcataaatc atgaagcctg
     1441 acaattattg acgtcttaat ttttaatcat cccttttaaa ggcttattta ataacaaaaa
     1501 agcagagtaa gattttttca ctcactctac ttttttaata aagttgtcgt ttataatact
     1561 gtttttacag cttctactaa agcatcaacc ttatttaaac gctcccatgg caaatcaata
     1621 tctgttctcc ccatgtgacc ataggcagct gtttgtttgt aaatcgggcg ttttaaatca
     1681 agcatttgaa taatgcctgc tggccgtaaa tcaaagactt gacgaacagc agcttctaaa
     1741 acagcttcag gaaccgttga ggttccaaat gtatccacgc gaacagacac aggctgagcc
     1801 accccaatcg cataagctag ttggacttca gctttcgtcg caagacctgc tgccacaagg
     1861 tttttagcaa tataacgagc agcataagaa gccgaacggt ccacttttgt cgcatctttt
     1921 cctgaaaaag caccgccacc atgacgtgaa tagcctccat aggtatccac aataatctta
     1981 cgtccggtca atccagagtc tccttgcgga cctccaataa caaaacgtcc tgttggatta
     2041 atgaagaact ttgtgtcatc atctaaataa tctgctggaa ttacagcctt gatcactttt
     2101 tcaatcacat cctgacgaat ttggtcatta gtagcttctg gatcatgctg agtagaaata
     2161 acgactgtat ccacacgaac aggtttatcg tgttcatcgt actcaactgt cacttgagat
     2221 ttagcatctg gacgtagata actaatctca cctgacttac gtaattccgc caagcgacgc
     2281 actaattggt gagataagga aattggtaaa ggcatcaatt ctggtgtttc attgatggca
     2341 aaaccaaaca tgagcccttg gtcacccgct ccaatatggc taaggtcatc agtatcacct
     2401 tctctgcttt cgagagcttc attaaccccc tgagcgatat ctccagattg ttctacaagt
     2461 gatggatgta ctcccactga ttctgctgaa aagccatatt ctgcttctgt ataaccaatt
     2521 tctgcaatgg tgtcgcggac cacacggtta atatcaatgt atgcttttgt tgagatttct
     2581 ccaaaaacat gaacagaacc tgtgtaaaca caagtttctg cagccacatg ggcttctgga
     2641 tcttctgcta aaatggcatc taaaatagca tctgaaattt ggtctgcaat cttatctgga
     2701 tgcccttcag atacggactc agacgtgaaa agtttacgtt ctgacataaa aatgtccccc
     2761 ctaatatgtt gattcttcct ttttcagtca cattgaccac aaagcaagaa gttgcctacc
     2821 cctttcttcc tagctgattg agcaagtcaa gtggccaaaa ccaacttagc taatcagtta
     2881 cggttttact agtaaggcaa ctagctagtc cacctagtgg ctagcgtcca ttaaccagac
     2941 aaagaatgtc tgacaatagc gttgagttac aaagaatccg gtttccttgt tgagaggatg
     3001 tcaccacaaa ataagcctta gacgaagtaa tttagctaaa gagagaacga ctgttcccca
     3061 aatgaagtca acaacgtctc aaaacatttc gttcaacaga ccgtcttatc gggactcaat
     3121 aacaatctat tataacatgt tttagccatt taggtgccat tcttttcact cattatccta
     3181 tttatttcaa aaaaacctca aggttattct tgaggttttc ttgatagtca acaatggtgt
     3241 cattaagacg attcagttgg atcgggttat tcttagatta gtttagtcag catggttttg
     3301 ctcatcttta gcttcatttt catcctcatg ttcatggtcg tgatcatctt tgtctctgtg
     3361 ctcgtgagca tgaccttctt catcttcata ggcatgatta tggttgtagt catgtgattc
     3421 cgatgcttct tgagcacttt ctttcgcctt agtagccata gctgcttttt cttcagctgt
     3481 tccattacct accatagaac cttcgtaaac cgctgggaag tttttcgcaa tggcttctgg
     3541 aatatgttgc tcgttcaatt taaggtctgc caatgggata ttgttatgac taatatcaat
     3601 gttagtaact gtcttattgg gtttagatag gttgacattt gttaattggt ttttagacac
     3661 gcttaaaatg tcaagtgctg taaaattatt aacaccttct agagaagtca actggttgcc
     3721 tgtcacatcc aagaaagtaa gtgacccttg cttgtcttta agcacaagcg atttaatttg
     3781 gttaccttct gcttctactc tgacaatgac gctacttgct tcaatacctt caagagattg
     3841 caattgcgca cggttaatag ataggctaga tagattagga ttatttttca agaaatccaa
     3901 atgagaaacc ttggtatcat tgaccattaa cgtttctaag ttgggtgctt gaagtgttgc
     3961 taagtcaaca tcagcatttc ttgataaatc aacaaccgtc aatgattctt tatgagaaac
     4021 agggcttaaa tctgtaatct gattattatc aatgtgcaat tcttgcaatt gatgtaacga
     4081 tgccagtggg cttaaatcag aaatcttatt attactcaat acgaggaatt tgagatttgg
     4141 taattgacca agcggcctaa tatcttcaat accattatca gcagccgcta ctagagttaa
     4201 gtttttatat ttgctcaaga aactaatatc tttgagattg ttttgtgaaa tatcaatgcc
     4261 ttctaactgt ggcatattat ccaaaaatct ataatcagtc acccctgttt ttgtcattag
     4321 taaccgtttc aattttttaa attgcaaaac aggtgagata tctttgattg gtgtaaagcc
     4381 aattcctaaa gtttctaagt tgggtaacag tgaaagtcct ttacgttgca aaggatcttt
     4441 acggctgccc aagtcaagtt tgataaccgt tgctaaccat tctttcatct tattcggatc
     4501 tttttcattt gatgggaatg aggttggagc atcgtgagtg cgaacgatat ccaaaatcac
     4561 ttcttcatca aaccctaagg cacgcaaggt atccattcca accttatgtt tttccaattc
     4621 acgggcatgc tcaatagcat gtggttctgg aatgtctttt ccgatttcaa tatcagataa
     4681 catcaatacg tgtgcgtggt catggtgagg gtattccaaa ccaagtttac cgtcttgtgt
     4741 ttccacacgt ttaatagttg atggatcaat ccccaatttt tctgccaaat aagctaattt
     4801 ttcttggtat tccttttcac gttcagatag ctctggtgtg tgaggggttt ctgctggctt
     4861 ttctgctttt ttagcgggat cgtattgatc tgccacatat gcccagccac cctgacgaag
     4921 gtccgcaaaa gaaataggat gtaagtgacc atcgtggtcc actaaaatac tgtcttttgt
     4981 taccccaaca ataccttgac cgttaaattg aaaaccatct gaggttggga aatgcaagcc
     5041 tggaatacca ttagctgtag ctgttgaaac agggctactg gtttgtggca agcgagtagc
     5101 aacctgttta gcttgtgcct gtgtctgacc tgataagctt gacttcaaaa tataatggaa
     5161 gtgatcatcg tggcgaaccg tgtagcctaa agcatcttca gccacaatat ccgctgggtt
     5221 aaattcataa tggtgatgag gatctgctac tttagaagtc ccttgactag ctgcttgctg
     5281 agcaacagct ggcttagcta aacttgctcc ttttggaata aggtattcaa atggacttcc
     5341 ctttaaatcg gcataaaaaa taaaatgcga atgaccatca tggtcaacaa cgattccctg
     5401 atctgttttt gataagattt ttgagtcttt ggttaaaata aacccatcat ctgtaggaaa
     5461 atcgacaccc gccatacctt tgtgagtctt gtttgtcttt ttgctttttt taatcggttt
     5521 aattttgttt gacgtcattc ccttacgtga ttgtttcgtt ttaatgggat atgtaccatt
     5581 acctcgtgat tgacaagata tcaaagtcaa ctgagatgat aacaatagac caactaaaat
     5641 aataactttt ttcgttttca ttcaaccctc ctttttattt aactggttaa gtatatcaca
     5701 tcacttgttt ttcctcaagc tctttttagg ataactatta gttgttgacg agttggagct
     5761 ctgaagcttc aacaaacaat agtttctgtt gttagtagca ttacacaaaa aaactaactt
     5821 ttcttttcct ttgaaaataa gatcttttat aatatactat acatatgaaa acatcagaaa
     5881 aaatttatca attactgtca caaaccgatg acttcgtcag tggggaatat ctagcagatc
     5941 aactcagtat ctctcgtaca tccgtttgga aatccatcaa aagtctcgaa aatcagggga
     6001 ttcaaattga ttctttaaaa cacaagggct accgcatggt acaaggtgat attttattac
     6061 ccaaaaccat tagccaaggg cttgggatgc cagtcaccta tacccctcac agccaatcta
     6121 cccaattaga tgccaaacaa ggaatcgaag ctcataacag cgctccaagg ctttacctag
     6181 ctcctagcca agaagctgcc aaaggacgcc tcgatcggca atttttttca gctagcaccg
     6241 gtggtattta catgtccatg tacctaaaac ccaatgtccc ttatgctgat atgcctcctt
     6301 atacgatgat ggttgcttcc agtattgtca aagctatctc gcgattaaca ggcattgata
     6361 cagaaatcaa atgggtaaac gacatctatc taggtaacca taaagttgca gggattctga
     6421 cagaagccat tacttctgtt gaaactggtt taatcaccga tgtcattatt ggggttggtc
     6481 tcaacttttt tgtcaccgac ttcccagaag cgattgctca aaaggcaggt tctctcttta
     6541 ccgaaaaacc gactatcacg cgcaatgacc ttatcattga catctggaaa ttattcttat
     6601 ctattcctgt caaggaccat gtcaaagttt acaaagaaaa atcacttgtt cttaataaac
     6661 aagtgacctt tacagaaaat agtcaagaaa aacgtgctat tgcgattgat ctcacagatc
     6721 aaggacacct cattgtacag tttgaaaatg gtgacttcca aaccttgcga agcggtgaaa
     6781 tcagtctttc ttcttgggag aattagccgt ttttaaaatg gttttagtca attggttaat
     6841 ggtatgcact cttcttaaat ccctaaagag caacaagccc caaaataagg cgaagagata
     6901 atttccagag agcaacaggt cattaaaaaa ataggtttca aaagcacata caaaggccat
     6961 aaaaagaaat tgtcgaatag tcatagcttt attataacag aaaaaaatga ttctatgaag
     7021 aatccacaca gattgat
//
LOCUS       DATWVB010000059         6888 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.059, whole genome shotgun sequence.
ACCESSION   DATWVB010000059 DATWVB010000000
VERSION     DATWVB010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6888
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.059"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(149..2725)
                     /locus_tag="VCX65_001609"
     CDS             complement(149..2725)
                     /locus_tag="VCX65_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEP5054059.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMGIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLTSMP
                     DAIYLFTLIKFGLIGLAACYSFHRLYPKINAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVVLGLNKLITENKTRTYYLSISLLFIQNYYFGYMIALFCILYALVCLLSLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPVKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPPTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPLNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIF
                     SNPDAKEVRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLLYKYIDIKSK
                     LL"
     gene            complement(2808..4427)
                     /locus_tag="VCX65_001610"
     CDS             complement(2808..4427)
                     /locus_tag="VCX65_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP5054060.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVIVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            complement(4506..5378)
                     /locus_tag="VCX65_001611"
     CDS             complement(4506..5378)
                     /locus_tag="VCX65_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP5054061.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     misc_binding    5501..5742
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5797..6819
                     /gene="trpS"
                     /locus_tag="VCX65_001612"
     CDS             5797..6819
                     /gene="trpS"
                     /locus_tag="VCX65_001612"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEP5054062.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
BASE COUNT         2396 a         1102 c         1246 g         2144 t
ORIGIN      
        1 cacgaaaaat ctgaccttta tattatttga gtttattagt aaaatcgata aaagcatctc
       61 aagtattaga atatttgtct agctcttgag atgcttttag tatattgact catttgccaa
      121 attgataaaa aaatctgatt tttttggact aaagtaattt agactttata tctatgtact
      181 tatacaaaag catataagcg ataattccta cgcaagatag agataaccct aatttaaaac
      241 cattaggaat aaaggtaagg ataacacgtc cctttccttt aggaatagta actgatagaa
      301 atcctccttg tgcttttttg actggaagat ttttcccatc tttttgtgct gaccaacctt
      361 tatcgtaagg aagtgtaaaa ataagagaac ctttcgtttt tgaattataa tcagtgatta
      421 ccgtattact tttagcgtaa gtatgaacat ttttttgttt aatactattc attgcttcaa
      481 ggtaagattc aatagacaaa ctataaaaat gaggttcctt aaaactaatt tgtttatttt
      541 ttggaaaaac aaacgaaaat gtagcaactt tggcatcggc gaaatatcct aaatcaaaaa
      601 aagagtaagc gttatctgta gtatatatga aattatgatt atctgtctga atacgcacct
      661 ctttagcatc aggatttgaa aatataatat tgggtatgct aacatagagt tgactatgtt
      721 tagggatgtt aatttgataa ttaagggtaa cggagttttg ataatcagaa gcttgtgcag
      781 atatttgtcc gttaaattga ttagcaccag aaataagttg agctggctgt aagttaaaat
      841 aggttaaaga tttcccactt agttggttaa gtaatttggt ttggttatca agggtattga
      901 catttagatt gacatctttg taaacattac gtgttaatat agctaaaggg ctactatagt
      961 gattttgata aagagtagta ttcccgctag tttttagttt tgtaaatcca aatttattta
     1021 gaggtccttc gctaagatta tattttatac caagtagact gtccataata atagtattgt
     1081 tttggtatct aaggtttaaa ttcgtgcctt tagactgaaa tcccaatcga tccaataaag
     1141 aactagatag tctatttctt acagaggaaa attgtgaaat gccgtaataa ttaaatttca
     1201 tgctatcgtt ccctgtttgg ggaagtagtc tttccattct aaaaaaaggt tgactatttt
     1261 ttgacacaga gttgacaagg ttgttaatat cctttaattg actattatat atctgtcgtg
     1321 atgggaatcc ccactcctta ttaattcctt gaagctggta gtaggtgttt aaccctgatt
     1381 caagaaggct aaagataagt atgaaagcag aaataaaagt aggtgggatt tgagaatttc
     1441 taaacgaaaa tagtgaaata gtataaccta ataataaaaa aacactaagt aaaaaaagag
     1501 ttaaaggtag aaaattatat tgttgagaaa agctataagg aagagatgtc agtataatga
     1561 ggaaaataaa agcaaaacct gcttttattt gagtcacttc ttttagtcga gagagagtct
     1621 cacatgcgag taataggata actatggaaa aagaccaagc gtagcgatgc aaaaacatat
     1681 ttggtgagtg catcccctgc caaaaaagat caagtggctg taggtaaaaa cttattataa
     1741 taaaagttaa caagcaggca ttggctaatt ttatttttaa agggatactt tctaaagtaa
     1801 aataaataac actaagcatt aggggaaata atcctacgta aatcataggc agagcattaa
     1861 acttggtagt atcgtacact cctattgaga gcttagcagg tatatccaaa aaccaagcat
     1921 tgttcgtaac taactgtttt accggggata gattctctcc ataagttgac aaatctagat
     1981 aggtaggaag tattaccaga gcacttgtta aagcagcaca tattgacaca gctgtaaacc
     2041 taacaaaagc gataaacatt ttgttaaaat cattgagact taaaagacaa actaaggcgt
     2101 aaagaataca aaaaagagca atcatgtagc caaagtagta attttgaatg aataataatg
     2161 atatcgaaag ataataagtt ctggttttat tttctgtgat aagtttattt aatccaagta
     2221 caacaagtgg aagaagaatg aaaacatcta accaagaatt tagttccatt tgacttgtca
     2281 agaagctcat taagctataa aaaactgaga tggaaatcat caagaaagca ttgatttttg
     2341 gatataatct atgaaaagaa tagcatgcag ctaatcctat taacccaaat tttatcaagg
     2401 taaacaaata gatagcatct ggcatagagg ttaaattaaa aaagaaaagt aatggagaaa
     2461 agaaactgcc aagataataa cacattaaag cataaaaatt tatccctagt ccgcttgtaa
     2521 aggtataaaa aaaactatca gaaccgtgca tgatgttacg aaagttctgc gcaaaaataa
     2581 catactgatg aaaagcatca ctagctagaa ttgttttatc actattataa taaatgccca
     2641 tcgatagaag gatgataaat ataatactaa gagggaacaa aaaactagca agtccagcaa
     2701 ttatccattt attattattt ttcataaatt atatggtctt tcgtttacaa attttaaaaa
     2761 agaggctagg aagagatctt cttagccacc tcatttatca taaggtttta tttccaaagt
     2821 tcagcaactc gggcttggac ttctggattg tcaaggaatt cgtcataagt ttcatctata
     2881 cggtcgataa caccattttt tgaaataaca acgatgtggt tagcaatcgt ttgaataaat
     2941 tcatggtcat gactggcaaa gataacagat tctttgaagt ctttgatccc atcattaaga
     3001 cttgaaatag attccaaatc caagtgattt gttggatcat caagaataag aacgtttgat
     3061 ttcaatagca tcaacttaga aagcatgaca cgcacttttt cgccaccgga aagaacgata
     3121 acagattttt taacttcgtc tccagagaaa agcatccgtc ctaggaaacc acgtaaaaaa
     3181 gtatcgtcat cttcaccttt tgaggcaaat tgacgtaacc attcaagaat agattcttcc
     3241 gtggcaaaat cttttgaatt gtctttaggc aagtaagaac gacttgttgt cactccccat
     3301 ttaatggttc cttcgtagtc aatatcatct gctaaagcac gcataagagc ggttgtttga
     3361 atatcatttt gaccaataat agcagctttg tcacctggac gtaaaatgaa actgatatta
     3421 tcaatgattt tctccccatc gatcgttaca gaaagatttt caacagtgag gaagtcattc
     3481 cccatttcac gctctgcttt aaaattaata aatgggtatt tacggcttga gggaacaatt
     3541 tcttctaatt caatcttatc aagcattttt ttacgagagg ttgcttgttt tgatttagat
     3601 gcgtttgctg agaaacgggc aacgaattct tgtaattctt tgattttttc ttcggcttta
     3661 gcattgcggt cagcttgtaa acgagcggct agctcagaag attgtttcca gaaatcgtag
     3721 ttacccacaa agagtttgat tttaccaaag tcaaggtcgg ccatgtgagt acatacttta
     3781 ttcaagaagt gacggtcatg ggaaacaacg atgactgtat tttcaaaatc aatcaagaaa
     3841 tcttctaacc atgaaataga ttgaatatca agaccattgg ttggctcgtc aagtaataaa
     3901 acgtcaggct taccaaagag cgctttagca agaaggactt tcactttatc tccattagcc
     3961 agttcactca tattttggta gtgaaggtct tctggaatat ttagattttg gagaagttga
     4021 gaagcttcac tttctgcctc ccagccacct aattcagcaa agataccttc tagctcagcg
     4081 gcacgaaccc catcttcttc tgaaaaatct gctttcatat agatagcgtc tttttctttc
     4141 atgatattgt aaagttgctc attacccatg attacaacat caatcgcacg ttcttcttca
     4201 taatcaaaat gattttggcg aagaacagat aagcgttcgt caggtcctaa agagatatga
     4261 ccagtacttg gttcaatatc tcctgcaagg attttaagaa aagttgattt tccggcacca
     4321 ttcgcaccga ttaagccgta agtattgccg gctgtgaatt tgatattaac atcatcaaat
     4381 agttttcgat cactaaagcg tagtgataca tcagaaactg taagcaattt gtcacctcat
     4441 tttatttatc taagcttcat tgtacctaaa atagtcccct ttttcaatca gaaaagggct
     4501 aatcactaca taggcaataa aacgtctttg tcttcacgtt tgtattgttt agtcaaacta
     4561 aatcctcttc ccataacttg agctgctggc atgacaacaa taaaggctgt gtcgtcaatt
     4621 tcgaggattt tttcttggag agtgggtaat tcgtgacttg atacaatagc cattaacata
     4681 attttatcag aagtagtata accaccgcga ataggaagtt tagtcactcc acgatccata
     4741 acagttgtga tatattctcg aatagcttga taatctttgg aaataatcat aacatttttg
     4801 gatgagtcaa agccattttc cataacgcta atcacataac caattacgaa aagtccaatc
     4861 gtagaataca tcacgtcatc tgcagaaagt gcaataaatc ccataaggac actaatacca
     4921 tctacaattg tcattgcaac tccaagagat aaaggagagt atttatgaag tatttgtgtt
     4981 agaattccag ttcctcctgt cgaagagttt ccccaaaaaa ccattcctaa accaatgcca
     5041 cagataatac caccaaaaat agctgctaac aactgattgt gtgtcagagt aggtaatgaa
     5101 ttggttgaac ggatggcaat aggatatatc caagaaccat aaagtgtttt aataaaattt
     5161 tgttttccaa gaaagaagta acacattaat aataagggaa tattactagc cattaaaaaa
     5221 agtgacggac taatgccaaa tagagctttt ataacaactg caataccaac cataccccct
     5281 gatgcaatat gattgtcgac aaacattgta ttgaaaccaa tagctgttat gaatgagcca
     5341 attgtgacaa gtagtaaatc aatccctcgt tttttcatgc ttttaatctc ctttataact
     5401 ggttaaaaat agtagactca ttatctctta aatgtactga gaccgtcaag tcatattttc
     5461 aaaaaatctg gtgaacttga caagaagttt aaaatttcat agaataaatt tgaattagaa
     5521 gagtattctt ttcatgtttt tagagagtta gtggttggtg caagctaaca acagaaaagg
     5581 tgaaatggac taatgattat ttgaaaggaa accataactt tcaggttggc accccttacc
     5641 gtgcagcttc tttcattgag aagattgaga tagtatctcg ttttgataaa gcagatgcta
     5701 attgaggtgg taccgcgtat tacttgtaat aacgccctca cgttttaata gcgtggggac
     5761 tttttgctat atcaagagat agttagggag aaaatgatga caaaacctat tattttaact
     5821 ggagatagac caactggaaa attacattta ggtcattatg tcggaagtct taaaaatcgt
     5881 gtctttttac aaaatgaaaa caagtataag atgtttgttt tcttggccga tcaacaggca
     5941 ctgacggatc atgctaaaga atccgaatta attcaagaat ctattggaaa tgttgccttg
     6001 gattacctct ctgtcggttt ggatccgaag caatcaacga tttttattca aagtcagatt
     6061 ccagagctag ctgaattgag catgtattat atgaatctgg tatcattagc acgtttggaa
     6121 agaaatccca ctgttaaaac cgaaattgct cagaaaggtt ttggcgaaag tattccatct
     6181 ggttttttgg tttatccagt atcacaggcc gctgatatta cagcatttaa agcgaattta
     6241 gtacctgtag gtaacgatca gaaaccgatg attgaacaaa cacgtgaaat tgtgagaagt
     6301 tttaatcata cttaccatac agactgttta gtagaacctg aaggtattta tccagaaaat
     6361 gaaaaagctg gacgcttacc tggtcttgat ggcaatgcca aaatgtctaa atcattggga
     6421 aatggaatct atctttcaga tgatgcagat accgttcgca aaaaagtgat gagcatgtat
     6481 actgatccaa atcatattaa aatagaagat cctggtcaaa ttgaagggaa tatggtcttt
     6541 cattatttgg atatttttgc tagaaaagaa gatcaagctg atatcgaagc aatgaaagag
     6601 cattatcaaa gaggtggttt aggagatgtg aaaacgaaac gctaccttct agatatttta
     6661 gaacgtgaat tagcacctat tcgtgaaaga cgtttggagt acgctaaaga tatgggagag
     6721 gtgttccgta tgttacaaga aggtagtcaa aaagcaagaa ctgtggcagc caagacttta
     6781 tcagaagtga agtcagcaat gggtattaat tatttttaat gttttagaga aaaagctaag
     6841 ttagtaatga taagataatt actattatca aagcaggacc taatttgt
//
LOCUS       DATWVB010000060         6843 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.060, whole genome shotgun sequence.
ACCESSION   DATWVB010000060 DATWVB010000000
VERSION     DATWVB010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6843
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.060"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            70..843
                     /gene="cfa"
                     /locus_tag="VCX65_001613"
     CDS             70..843
                     /gene="cfa"
                     /locus_tag="VCX65_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HEP5054063.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQA
                     NLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKA
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKSFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS"
     gene            complement(1213..2448)
                     /locus_tag="VCX65_001614"
     CDS             complement(1213..2448)
                     /locus_tag="VCX65_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEP5054064.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLLLSAAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLI
                     HTIKRIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMILEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLVDANGQ
                     TVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQHTSIWRRHESWSLLFHQ
                     ITPIAKRQLHHTHYRIVKM"
     gene            complement(2568..3890)
                     /locus_tag="VCX65_001615"
     CDS             complement(2568..3890)
                     /locus_tag="VCX65_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEP5054065.1"
                     /translation="MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNESVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     regulatory      complement(4018..4104)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            4419..6737
                     /gene="pcrA"
                     /locus_tag="VCX65_001616"
     CDS             4419..6737
                     /gene="pcrA"
                     /locus_tag="VCX65_001616"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEP5054066.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALSLNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
BASE COUNT         2293 a         1279 c         1342 g         1929 t
ORIGIN      
        1 aagcgcttat aaattaattt aacttcactt aactatttaa ataggtttat tatattcagg
       61 aggaataata tgaaacccaa acaccttctc tgtctttcaa cagttgttgc tggattagct
      121 ttattttcaa ctatgacgca ctcagtttta gctgatgatg cttcaaatcc cgatactatt
      181 ttaatgaata acaaccaagc gaatcttcaa agagacgctc tagtgcaaaa gcttgatgag
      241 ggacatcaac aattagaagc tattaaacat gaagctaaag gtactgatat tgaggctact
      301 gttaacaaag ctatcgatgc tgttgatcac atgaagagtt ctatacgctt caatactgaa
      361 acgatctatg attttagttc aattggggca agagtagaag cattatcaga tgctatcaaa
      421 gcaatcgtat tttccacaac ccaattaact cacaaagtag aaaaagcgca tactgatatg
      481 gggtttgcta ttactaaatt agtcattcgt attatagatc catttgcatc tgttgacgct
      541 atcaaagctc aagtacaaga aattaaagca cttgaggaaa aagttatcaa ttatcctgat
      601 ttacagccaa cagaccgtgc tactatctat actaaagcta aactaaataa agctatttgg
      661 aacactcgtt tagaaagaga taaaaaggtt ttagggatca aatcatttga cgtttataat
      721 agacttaaca aagctatcac acatgcggtt ggtgtccaac taaatccgac aaccactgtt
      781 caacaagttg acgatgaagt tattgctgtg caaaatgctt tggaaacagc tcttaagtca
      841 tagagtgtat aagtaatgtg ttgtataggt agatgattat attaggatat agaataggta
      901 aagattttaa atatcttacc attgtagagt ttgaggtgat gttctcataa acaatgagtc
      961 acctgtagcc ctttttgcct ttaacatgat gtaccaattt aaggtattgt tcaaccgtca
     1021 ctattgaatc ttgtttaacc tcctaaacta ataagattca atatgaaaac gtgtattctt
     1081 aaaaaaatcc ctatgatctg tttaaaaaca aattgtaggg atttttttaa ctatttaact
     1141 tattattttg ggactaggaa tcgctttagg aatatcatga agtatagtta tgttataaga
     1201 taagtaatgt ttttacattt ttacaatacg atagtgtgtg tgatgtaatt gtctcttagc
     1261 gataggggta atttggtgga agagtaagga ccaagattca tgacgcctcc aaatactggt
     1321 atgttgattg ccatttaatt ggtaagttac caacatcgtt ttttgactaa tggattcaat
     1381 ctgaaaatgg ttgaagttac ttggataata aatttcttgg ttcaaaaatt gttcatagtt
     1441 aactgtttgg ccattcgcat caaccagttg gaaagactta gcaatgtagt ggtcatagtc
     1501 aggaacctta ctcaaaatta atttttcgta gcggtagagc tttttggcga cattatcaaa
     1561 aatctcttct tcgagaatca tggcaggttc aacgtgaata tcaatgtcat aaatagaaaa
     1621 ttggtcactc aataactgct ccactttctc tgtaatagag tgactttcat agactgaaag
     1681 atcaggattc atttcaagta caatatcaag atagacattg ctaccatagg tcctagctcg
     1741 ttgagactta acggcgacaa ttttagggat ttctaaaatg gctttttcgt attttttcaa
     1801 atgacggcta tcaaatccat cagataaact aaacgaactt tccataaaga tatcaaaagc
     1861 tgttttaaga ataaagaacg taatgatcat agcagctata tgatcgataa ctggtaaatg
     1921 caaagaagct gctataatag caattgatgt tccgatagaa gtaacagcat cagctagatt
     1981 atccttagaa gcagcgacta aggcactgga ttttacacgt ttggaaagac gtttgttaaa
     2041 gacatagacc cctaacataa caaaagctga aacgataccg acaatagccc caagagggtc
     2101 aatatcaact tgctgaccac taaagatacg tttaattgtg tgaatcagta cttggaaacc
     2161 tacaagaaac ataataaaag aagtgacaag gctggataaa tcttcaattt tccaatgacc
     2221 aaatttatga ttggcatcgg ctggttggct agctaagtga agaccaataa gcagggctac
     2281 atttcccaca atatccgata aattgttaaa tccatcagca ataagggaac ttgcatttaa
     2341 caaataacca gctaataatt tggcagcact aagcaacaag tagacaataa tactaacgat
     2401 tgggcccttt ctggctagtt ttaaatttgc aatcggatcc tgtgtcataa taactccttt
     2461 gatttcaact ttatattata ccataaaaag gggcttaaga aaaaagccta gcttcttgaa
     2521 cttggcagaa gaagactagg tataactggg tagtactaac gtcatgttta cttaataaag
     2581 taatgcttgg tttctaaaat aacaactggc gagagagcta ggagggcaat caggttagga
     2641 agtgccatta aaccattgac aatatcagcc aaaacccaaa tcagttctaa cttaaggaag
     2701 cctcctaggc ctaccattaa gataaagaca atacggaagt aggtgagatg tgtaatgcca
     2761 aagaggaatt caaagcagcg ttctccataa taactccatc ctaaaatcgt tgtaaaggcg
     2821 aagagaacta gggaaaaggt taggccaaaa gtccctaaat ttccaaacac agtggcaaag
     2881 gcagattggg tcagaggagc cccttcgagc tgcccagtcc attggcctgt tactaaaata
     2941 gataggccgg ttagggtaca gataataatc gtatcaataa aagttcctgt catggagatc
     3001 aggccctgct ccacggattc attggtttta gctgctgctg cagcaatagg tgcagatcct
     3061 agtccagact cattggagaa gacaccgcgt gcaattcctt tttgaatggc atccttcatg
     3121 agacttccag caaagcctcc aatagcagct gtcggagtga aggctgattg aaagactaaa
     3181 cgaataacag gaagtagctg ctggtagtga ctaaaaataa ctgctaaact agatagaata
     3241 taaaaaatag ccataaaagg aacgactttt tcagccactt tggaaatgga atgaatgcca
     3301 ccaaaaataa tggcagccac aaagatagct aaaacaatac tgaccatttg tggggataag
     3361 ccaaagctat gacctaaaga cgaggtgatc gagttcactt gagcaaaggt tcctattcca
     3421 aatagggcaa ctaggatccc tgaacccgca aaaagaatgg ctaagggttt ccattttgtc
     3481 cccatgccat taacaatata gtacatagga ccaccagaaa tatgaccgtt ggcatccttt
     3541 gtacggtatt taatcgctag taccccttca gcgtacttag tggccattcc aaaaaaagcg
     3601 gcaacccaca tccaaaagag cgctccagga ccaccagact tgatagcagt ggcaacccca
     3661 acaatgttac cagttccgac agtagcggca agggcagttg caagagcagc aaaggatgaa
     3721 atatctccat gtccttcgtc atctgaaaaa atgagtttaa aggctcttgg tagttttaag
     3781 atttgaatta atcctaaacg actggtaagg taaatccccg tcccaaccaa taaaattaag
     3841 aggggcggtc cccaaacaag gttatcaatt aatttaacga gtgctatcat ctttctctcc
     3901 taaaagtcat cgaagacgcc aaaagaaaaa agctatctct ttctttgaga caacttctga
     3961 agcaatgata aaacagcaaa cacaaaaaag actaagactg ttcttaatgg tgtttgtatt
     4021 ttaccttctg tccttttgcc tgagagattg agcagtatgc cttgcccctt cggcgcctaa
     4081 taaggtctct ccagaagtcc gtccatcaaa cagtcccgtt caaaaactga acacctgaga
     4141 gtataactcc ttcggcgaaa aaaattcttc tcctgcatga catcattcgg tttattaaat
     4201 taggactatc atacctcaaa aaacgaatga agtcaaccaa aatagcaaaa aaataaggaa
     4261 tgctttaaga aatcgctatt atttttaaat atctgatcct aaactagaaa aaaggaatct
     4321 ctttactttt ggggtcttct ttgctatttt tcttggaaac atgatataat tttaaggttg
     4381 ataaaagaga tgtcactgaa cgagattaag gagaaagcat gaatccttta ttaaatggaa
     4441 tgaatgatcg gcaggcacaa gctgttcaaa caactgaagg ccccttattg attatggcgg
     4501 gggctggttc tggtaaaaca agggtactga cccatcgtat tgcctattta attgatgaaa
     4561 aatttgtcaa tccttggaat attttagcta ttacctttac taataaggct gcgcgtgaaa
     4621 tgaaagaaag agccttgtcc ttaaatccag ctactaaaga taccttaatt gctacctttc
     4681 actccatgtg tgtacggatt ctgcgtcgtg aggctgatca cattggttac aaccgaaact
     4741 tcacaatcgt ggatccaggt gagcaacgaa cgttgatgaa gcgcatttta aaacaattaa
     4801 atatagaccc taaaaagtgg aatgaacgtt ctattttagg aactatttca aacgctaaaa
     4861 atgatttgct tgatgaaaag ggatacgagg cacaggctgc tgatatgtat agtcaaatcg
     4921 tagcgaggtg ttacaaagct tatcaggaag aattacgacg tagcgaagca cttgactttg
     4981 atgatttaat catgatgacg ctacgcctgt ttgacgctaa tcctgacgtg ttagcttatt
     5041 accagcagcg ttaccaatac attcatgtgg atgagtacca agataccaac catgctcaat
     5101 atcagctaat taaattgcta gcttctcgct ttaaaaatat ttgcgttgtt ggagacgctg
     5161 atcagtctat ctatggttgg cggggagctg acatgcaaaa tattcttgat tttgaaaaag
     5221 attacccaga tgctaaggta gtgcttttag aagaaaacta tcgctctacc aagaaaattc
     5281 tgcaagcagc taacgacgtg attaacaata accgtaatcg ccgtcctaag aaactttgga
     5341 cacaaaatgc ggatggtgaa caactggttt attaccgggc aaatgatgag cgagatgagg
     5401 cagtatttgt ggcctcaacc attagcaata tgagtcaaga gcttggaaaa aacttcaaag
     5461 atttcgctgt tttataccgt accaatgccc aatctcggac cattgaagaa gcactcttaa
     5521 aatccaatat tccttacacc atggttggag gcaccaagtt ttacagccgt aaagaaattc
     5581 gggatttgat tgcctattta accattgttg ctaaccctgc tgataatatt tcttttgagc
     5641 ggattgtgaa tgagcctaaa cgaggtgttg gtccaggaac gcttgataaa ctgcgtcagt
     5701 ttgcctatga gagtgaccag tctttattag aagcagcttc aaatctattg atgtccccct
     5761 tgaaaggtaa agcagcacaa gctatcatgg acttggccaa tattctcggt cagctacgtc
     5821 aagacctaga tcagatgagt atcaccgact tagcagaagc tttgttagaa aaaacaggtt
     5881 atttagatag cttacgcctg caaaatacat tggaaagcca agcccgtatc gaaaatatcg
     5941 aagaattctt atctgttacc aaaaattttg acgagtcaag tgcctctcaa gaagaagacg
     6001 aaaccggtgt tgatcgcttg ggacgttttt taaacgattt agcactgatt gctgatacag
     6061 atgattccca agcagaagct gctgaagtaa ccttaatgac cctacatgct gccaaaggct
     6121 tggagttccc tgttgttttc ttaattggta tggaagaagg tgtcttcccc ttatcacgtg
     6181 cctctgaaga tccagatgaa ttggaagaag aaagacgttt agcttatgtc ggaatcacaa
     6241 gagctgaaga agttctcttt atgaccaatg ccaacaccag aaccctcttt ggtaaaagta
     6301 gttataaccg tccaacacgc ttcttgaaag aaatttcaga ggaactactc tcttataaag
     6361 gattggcaag accagcacaa tcttcatttg gtgtgcgttt ttctactgaa acacacacac
     6421 agtttggaca agggatgagc ctatcagaag ccttacaagc tcgaaaggcc caggctcaag
     6481 taagacaatc agcacagcca atgcaggcac atacgatacc atcagcttca actagctcag
     6541 ttttaccgtt tggttctaat agctctgtag aagaggtcac ttggcagatt ggcgatatcg
     6601 ctcaccataa aaaatgggga gacgggactg tgcttgaggt ttcaggctcc ggaaaaacga
     6661 tggaattgaa aatcaaattt ccagaagttg gtctaaagaa attactagca agtgttgctc
     6721 ctattgagaa aaaataagaa aaaaatgagc ttcctactat ataagtgagt aggaagctca
     6781 tttttttaga tttctgtatc atataaaagt taaaaaattt taagttttag gagcatatca
     6841 gtt
//
LOCUS       DATWVB010000061         6599 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.061, whole genome shotgun sequence.
ACCESSION   DATWVB010000061 DATWVB010000000
VERSION     DATWVB010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6599
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.061"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            81..4187
                     /gene="cas9"
                     /locus_tag="VCX65_001617"
     CDS             81..4187
                     /gene="cas9"
                     /locus_tag="VCX65_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HEP5054067.1"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIK
                     KNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLE
                     ESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAH
                     MIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSK
                     SRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLD
                     NLLAQIGDQYADLFLAAKNLSDAILLSDILRLNSEITKAPLSASMIKRYDEHHQDLTL
                     LKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAK
                     LNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPY
                     YVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVL
                     PKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAIVDLLFKTNRKVTVKQLKE
                     DYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLT
                     LFEDREMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDF
                     LKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQT
                     VKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKE
                     HPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKV
                     LTRSDKNRGKSNNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKA
                     GFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQF
                     YKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIG
                     KATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLS
                     MPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVV
                     AKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVRKDLIVKLPKYSLF
                     ELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQH
                     KHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGA
                     PAAFKYFDTTIDRKRYTSTKEVLDATFIHQSITGLYETRIDLSQLGGD"
     gene            4187..5056
                     /gene="cas1"
                     /locus_tag="VCX65_001618"
     CDS             4187..5056
                     /gene="cas1"
                     /locus_tag="VCX65_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HEP5054068.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVK
                     SQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTL
                     FGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDI
                     MEPFRPLVDKIVYENRNQPFPKIKRELFTLFSDTFSYNGKEMYLTNIISDYTKKVVKA
                     LNNEGKGVPEFRI"
     gene            5053..5394
                     /gene="cas2"
                     /locus_tag="VCX65_001619"
     CDS             5053..5394
                     /gene="cas2"
                     /locus_tag="VCX65_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEP5054069.1"
                     /translation="MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSI
                     YSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDER
                     LVFLGEAFDES"
     gene            5384..6046
                     /gene="csn2"
                     /locus_tag="VCX65_001620"
     CDS             5384..6046
                     /gene="csn2"
                     /locus_tag="VCX65_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HEP5054070.1"
                     /translation="MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYKYEEDSEL
                     KFFDRKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVA
                     TITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTK
                     KKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKN
                     MV"
BASE COUNT         2265 a          974 c         1307 g         2053 t
ORIGIN      
        1 tcggaggtca ttaaaactat tagtgaaatc atcaaactca ttatggattt aatttaaact
       61 ttttatttta ggaggcaaaa atggataaga aatactcaat aggcttagat atcggcacaa
      121 atagcgtcgg atgggcggtg atcactgatg attataaggt tccgtctaaa aagttcaagg
      181 ttctgggaaa tacagaccgc cacagtatca aaaaaaatct tataggggct cttttatttg
      241 acagtggaga gacagcggaa gcgactcgtc tcaaacggac agctcgtaga aggtatacac
      301 gtcggaagaa tcgtatttgt tatctacagg agattttttc aaatgagatg gcgaaagtag
      361 atgatagttt ctttcatcga cttgaagagt cttttttggt ggaagaagac aagaagcatg
      421 aacgtcatcc tatttttgga aatatagtag atgaagttgc ttatcatgag aaatatccaa
      481 ctatctatca tctgcgaaaa aaattggtag attctactga taaagcggat ttgcgcttaa
      541 tctatttggc cttagcgcat atgattaagt ttcgtggtca ttttttgatt gagggagatt
      601 taaatcctga taatagtgat gtggacaaac tatttatcca gttggtacaa acctacaatc
      661 aattatttga agaaaaccct attaacgcaa gtggagtaga tgctaaagcg attctttctg
      721 cacgattgag taaatcaaga cgattagaaa atctcattgc tcagctcccc ggtgagaaga
      781 aaaatggctt atttgggaat ctcattgctt tgtcattggg tttgacccct aattttaaat
      841 caaattttga tttggcagaa gatgctaaat tacagctttc aaaagatact tacgatgatg
      901 atttagataa tttattggcg caaattggag atcaatatgc tgatttgttt ttggcagcta
      961 agaatttatc agatgctatt ttactttcag atatcctaag attaaatagt gaaataacta
     1021 aggctcccct atcagcttca atgattaaac gctacgatga acatcatcaa gacttgactc
     1081 ttttaaaagc tttagttcga caacaacttc cagaaaagta taaagaaatc ttttttgatc
     1141 aatcaaaaaa cggatatgca ggttatattg atgggggagc tagccaagaa gaattttata
     1201 aatttatcaa accaatttta gaaaaaatgg atggtactga ggaattattg gcgaaactaa
     1261 atcgtgaaga tttgctgcgc aagcaacgga cctttgacaa cggctctatt ccccatcaaa
     1321 ttcacttggg tgagctgcat gctattctga gaagacaaga agacttttat ccatttttaa
     1381 aagacaatcg tgagaagatt gaaaaaatct tgacttttcg aattccttat tatgttggtc
     1441 cattggcgcg tggcaatagt cgttttgcat ggatgactcg gaagtctgaa gaaacaatta
     1501 ccccatggaa ttttgaagaa gttgtcgata aaggtgcttc agctcaatca tttattgaac
     1561 gcatgacaaa ctttgataaa aatcttccaa atgaaaaagt actaccaaaa catagtttgc
     1621 tttatgagta ttttacggtt tataacgaat tgacaaaggt caaatatgtt actgagggaa
     1681 tgcgaaaacc agcatttctt tcaggtgaac agaagaaagc cattgttgat ttactcttca
     1741 aaacaaatcg aaaagtaacc gttaagcaat taaaagaaga ttatttcaaa aaaatagaat
     1801 gttttgatag tgttgaaatt tcaggagttg aagatagatt taatgcttca ttaggtacct
     1861 accatgattt gctaaaaatt attaaagata aagatttttt ggataatgaa gaaaatgaag
     1921 atatcttaga ggatattgtt ttaacattga ccttatttga agatagggag atgattgagg
     1981 aaagacttaa aacatatgct cacctctttg atgataaggt gatgaaacag cttaaacgtc
     2041 gccgttatac tggttgggga cgtttgtctc gaaaattgat taatggtatt agggataagc
     2101 aatctggcaa aacaatatta gattttttga aatcagatgg ttttgccaat cgcaatttta
     2161 tgcagctgat ccatgatgat agtttgacat ttaaagaaga cattcaaaaa gcacaagtgt
     2221 ctggacaagg cgatagttta catgaacata ttgcaaattt agctggtagc cctgctatta
     2281 aaaaaggtat tttacagact gtaaaagttg ttgatgaatt ggtcaaagta atggggcggc
     2341 ataagccaga aaatatcgtt attgaaatgg cacgtgaaaa tcagacaact caaaagggcc
     2401 agaaaaattc gcgtgagcgt atgaaacgta ttgaagaagg tatcaaagaa ttaggaagtc
     2461 agattcttaa agagcatcct gttgaaaata ctcaattgca aaatgaaaag ctctatctct
     2521 attatctcca aaatggaaga gacatgtatg tggaccaaga attagatatt aatcgtttaa
     2581 gtgattatga tgtcgatcac attgttccac aaagtttcat taaagacgat tcaatagaca
     2641 ataaggtctt aacgcgttct gataaaaatc gtggtaaatc gaataacgtt ccaagtgaag
     2701 aagtagtcaa aaagatgaaa aactattgga gacaacttct aaacgccaag ttaatcactc
     2761 aacgtaagtt tgataattta acgaaagctg aacgtggagg tttgagtgaa cttgataaag
     2821 ctggttttat caaacgccaa ttggttgaaa ctcgccaaat cactaagcat gtggcacaaa
     2881 ttttggatag tcgcatgaat actaaatacg atgaaaatga taaacttatt cgagaggtta
     2941 aagtgattac cttaaaatct aaattagttt ctgacttccg aaaagatttc caattctata
     3001 aagtacgtga gattaacaat taccatcatg cccatgatgc gtatcttaat gccgtcgttg
     3061 gaactgcttt gattaagaaa tatccaaaac ttgaatcgga gtttgtctat ggtgattata
     3121 aagtttatga tgttcgtaaa atgattgcta agtctgagca ggaaataggc aaagcaaccg
     3181 caaaatattt cttttactct aatatcatga acttcttcaa aacagaaatt acacttgcaa
     3241 atggagagat tcgcaaacgc cctctaatcg aaactaatgg ggaaactgga gaaattgtct
     3301 gggataaagg gcgagatttt gccacagtgc gcaaagtatt gtccatgccc caagtcaata
     3361 ttgtcaagaa aacagaagta cagacaggcg gattctccaa ggagtcaatt ttaccaaaaa
     3421 gaaattcgga caagcttatt gctcgtaaaa aagactggga tccaaaaaaa tatggtggtt
     3481 ttgatagtcc aacggtagct tattcagtcc tagtggttgc taaggtggaa aaagggaaat
     3541 cgaagaagtt aaaatccgtt aaagagttac tagggatcac aattatggaa agaagttcct
     3601 ttgaaaaaaa tccgattgac tttttagaag ctaaaggata taaggaagtt agaaaagact
     3661 taatcgttaa actacctaaa tatagtcttt ttgagttaga aaacggtcgt aaacggatgc
     3721 tggctagtgc cggagaatta caaaaaggaa atgagctggc tctgccaagc aaatatgtga
     3781 attttttata tttagctagt cattatgaaa agttgaaggg tagtccagaa gataacgaac
     3841 aaaaacaatt gtttgtggag cagcataagc attatttaga tgagattatt gagcaaatca
     3901 gtgaattttc taagcgtgtt attttagcag atgccaattt agataaagtt cttagtgcat
     3961 ataacaaaca tagagacaaa ccaatacgtg aacaagcaga aaatattatt catttattta
     4021 cgttgacgaa tcttggagct cccgctgctt ttaaatattt tgatacaaca attgatcgta
     4081 aacgatatac gtctacaaaa gaagttttag atgccacttt tatccatcaa tccatcactg
     4141 gtctttatga aacacgcatt gatttgagtc agctaggagg tgactgatgg ctggttggcg
     4201 tactgttgtg gtaaataccc actcgaaatt atcctataag aataatcatc tgatttttaa
     4261 ggatgcctat aaaacggagc tgatccattt atcagaaatt gatattttgt tattagaaac
     4321 gaccgatatt gtcttgtcca ctatgctggt aaaacggcta gtggatgaga atgtccttgt
     4381 catattctgt gatgataaac gattaccaac agctatgctg atgccttttt atggtcgtca
     4441 tgattcgagt ttacagcttg ggaaacaaat gtcctggtca gaaacagtca aatcgcaggt
     4501 ttggacgacg attattgctc aaaagatttt gaatcaatct tgctatctag gagcatgctc
     4561 ctattttgaa aaatcccaat ctattatgga tttatatcat ggtttggaaa attttgatcc
     4621 gagtaatcga gaagggcatg cagcgagaat ttattttaat acactttttg ggaacgattt
     4681 ctcaagagat ttggagcatc caatcaatgc aggtctggat tatggttata ctttattatt
     4741 gagtatgttt gcgcgtgaag tggttgtgtc tggatgtatg actcagtttg ggcttaaaca
     4801 cgctaatcag tttaatcagt tcaattttgc tagcgatatt atggaaccat ttaggccttt
     4861 ggtggataag attgtttatg aaaatcgaaa tcagcctttt cccaaaataa agagagagtt
     4921 atttactttg ttttcagata cattttcata taatggtaaa gagatgtatc tcacgaatat
     4981 tattagcgat tatactaaaa aagttgtcaa agctctgaat aatgaaggga aaggagttcc
     5041 tgaatttagg atatgagtta tagatatatg agaatgatac ttatgtttga tatgccgacg
     5101 gacaccgctg aggaacgaaa agcctatcga aaatttcgga aatttttact tagtgaaggg
     5161 tttatcatgc atcaattttc tatttatagt aagttgctgt tgaataatac agctaacaat
     5221 gccatgattg gtcggctgag ggagcataat cctaataaag gaaatattac attactaacg
     5281 gtcacagaaa aacagtttgc acgaatgatt tatttacatg gtgaaagaaa taattgtatt
     5341 gcaaactccg atgaaagact tgtatttctt ggggaggctt ttgatgaatc ttaatttttc
     5401 cttactagat gaaccgattc cattaagagg cggtacaatt cttgtgctcg aagatgtctg
     5461 tgtattttca aaaatagtgc aatattgtta caaatatgag gaagattctg aacttaaatt
     5521 ttttgatcgc aagatgaaaa ccatcaaaga atcagaaatc atgcttgtaa cagatatttt
     5581 aggatttgat gttaactcct caaccatttt aaaattgatt catgcagatt tagaatctca
     5641 atttaatgag aaacccgaag tgaaatcgat gattgacaaa ttggttgcta cgattacaga
     5701 actgattgtc tttgaatgct tagaaaatga attagattta gagtatgatg aaatcacaat
     5761 cctggaattg attaagtcct taggagtaaa agtagaaacg caaagtgata ctatttttga
     5821 aaaatgtcta gagatacttc aaattttcaa atatctcact aagaaaaagt tgcttatttt
     5881 tgtcaatagc ggagcttttc taacaaagga tgaagtggct agtttacaag agtatatatc
     5941 attgacaaat ttaacagttc tctttttaga accacgtgaa ctatatgatt ttccgcagta
     6001 tattttagat gaagattatt tcttaataac taaaaatatg gtataatact cttaataaat
     6061 gcagtaatac aggggctttt caagactgaa gtctagctga gacaaatagt gcgattacga
     6121 aattttttag acaaaaatag tctacgaggt tttagagcta tgctgttttg aatggtccca
     6181 aaactgctcc agatggattt ttaaactgat tattgtttta gagctatgct gttttgaatg
     6241 gtcccaaaac tagaaattga caatgctttt tcttttgtct gttttagagc tatgctgttt
     6301 tgaatggtcc caaaacgaca tattaacgtc ctttctcctg ctttccgttt tagagctatg
     6361 ctgttttgaa tggtctccat tcaacattgc cgatgataac ttgagaaaga gggttaatac
     6421 cagcagtcgg atacccacgc caaacgcatg aagaaacttt tgttttcaga aaactagatt
     6481 cataatgaca aaatcaatca aagtagtaca ctatagatga ggtgactacg atgattgatt
     6541 ttattatttc tattgatgat tgtgcagttg aattggatag tcgtcaatct tggaaaatt
//
LOCUS       DATWVB010000062         6484 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.062, whole genome shotgun sequence.
ACCESSION   DATWVB010000062 DATWVB010000000
VERSION     DATWVB010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6484
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.062"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..860
                     /locus_tag="VCX65_001621"
     CDS             <1..860
                     /locus_tag="VCX65_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEP5054071.1"
                     /translation="TDDLKPFQVRDLVSGHLERIQEEVEKKYPNAGFNSDKYNGLKES
                     NSLLSDGFEVKSGNLIFDKKLTIPLTTLFDVINPDFLANSDRAAYDNYRTYKEQHPKK
                     LVALTFDDGPDPTTTPQVLDILAKYQAKGTFFMIGSKVVNNENLTKRVSDAGHEIANH
                     TWDHPNLTNLSVSEIQHQVNMTNQAIEKACGKKPRYLRPPYGATNATVQQSSGLTQML
                     WTVDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDIHQTTINALPAVMEYLKAEGYECV
                     TVSELYAHQ"
     gene            complement(970..2055)
                     /locus_tag="VCX65_001622"
     CDS             complement(970..2055)
                     /locus_tag="VCX65_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP5054072.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFANIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            2153..2779
                     /gene="udk"
                     /locus_tag="VCX65_001623"
     CDS             2153..2779
                     /gene="udk"
                     /locus_tag="VCX65_001623"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEP5054073.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            2859..3122
                     /locus_tag="VCX65_001624"
     CDS             2859..3122
                     /locus_tag="VCX65_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEP5054074.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERNLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK"
     gene            complement(3175..3984)
                     /locus_tag="VCX65_001625"
     CDS             complement(3175..3984)
                     /locus_tag="VCX65_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEP5054075.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     AEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            4129..4626
                     /locus_tag="VCX65_001626"
     CDS             4129..4626
                     /locus_tag="VCX65_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEP5054076.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPN
                     SVFAGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNM
                     FGVKN"
     gene            4626..6311
                     /gene="dnaX"
                     /locus_tag="VCX65_001627"
     CDS             4626..6311
                     /gene="dnaX"
                     /locus_tag="VCX65_001627"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEP5054077.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVTIAIAEEITGSISMLALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAKEEGVALPSGLSSDVTTEVEGLKRELNQLKQALAQLQASPS
                     PSHAPVKPAQAKPKLTTYKIDRVKILKIMEETVQDSQQSRQYLDALKTAWNEILDSIS
                     AQDRALLMGSEPVLANSENAILAFEAAFNAEQAMKRTDLNAIFGNIMSKAAGFSPNIL
                     AVPKADFHHIRSEFALQLKTQKASDPTEETIEETLEIPEGFDFLVDKINAVED"
BASE COUNT         2084 a         1095 c         1335 g         1970 t
ORIGIN      
        1 ttacagacga cttgaaaccg tttcaggtaa gggatctagt atcaggacat ttagaaagaa
       61 tacaagaaga agttgaaaaa aaatatccaa atgctggttt taatagcgat aagtacaatg
      121 gcttaaaaga atctaattct ttattaagcg atggctttga ggtaaaatcg ggaaacctta
      181 tttttgataa aaagctaacg atacctttga cgacattatt tgatgttatt aatccagatt
      241 ttttagcaaa tagcgataga gctgcgtatg ataattatag gacctacaaa gaacagcatc
      301 ccaaaaaact agttgcatta acgtttgatg atggtccaga tccgacgacg actcctcaag
      361 ttttagatat tttggcaaaa taccaggcta agggaacttt ctttatgata ggttcaaaag
      421 ttgtgaataa tgaaaacctt actaaacgtg ttagcgacgc tggccatgaa attgctaatc
      481 atacttggga tcatcccaat ctgactaatc tttcagtcag cgagattcaa catcaagtta
      541 atatgacgaa ccaggctatt gaaaaagctt gtggcaagaa acctcgctat ttacgccctc
      601 catacggagc tacaaatgca actgttcagc aatcctcagg attaacacaa atgctttgga
      661 cggttgatac aagagattgg gaaaatcata gcactgatgg cattatgact aatgtcaaaa
      721 accaattgca accgggagga gttgttttaa tgcatgatat tcatcaaaca actatcaatg
      781 ctttgccggc agttatggaa tatctaaaag cagaaggata cgaatgtgtg actgtatcag
      841 aactctatgc gcatcagtaa gtaatatcgt tatgtttctt tagaattgat atactaaaca
      901 atccaattac tttgaagtaa ttggattgtt gtttttagta gcccttgatt aagttttgtt
      961 ttttaacaac tagttgatga aatgaagttg ttgatttttg agggagattt cagagacttt
     1021 agcaaatttt ttcaattttt tgaggtcttc agggtggcta acaaaggtaa taacgatacc
     1081 agattttccc atacggccgg ttcgtccagc tctgtgagta taattttcct tatcacgagc
     1141 aacatcaaaa tgaatgacat agtcaagatt atcaatatca atgccccgag caacaagatc
     1201 cgtagctaac aataaggaga gttggtggga tttgaatttt tcgagaatgg ttttacggaa
     1261 tttgacattg atgtcactcg ctaaggaaac cgcagcagct ccattatatt ggagacgttc
     1321 ttccgtagca cccaaatcag ataaactgtt gaaaaagact aaagctctaa aatgaggaat
     1381 attagcaaat tttcgtaata aatcggtacg ttcgcgcttg tcaaccatga ggtaaaaatg
     1441 ctgaatagca tcgttggttt gctctgaaag atcgatgcag aatgtatttg gagctaagga
     1501 agtttgatcc accttattag tagcactcat gtataccatt tgatgatctc gaggaacata
     1561 gtggctaatt ttttgaacaa aatcatattg ggaatcacct aatagttcgt catattcatc
     1621 taaaacaatg gtgttgacag acatcatctt gatttttttc aatttaatca gttcaaaaat
     1681 gcgtccaggg gtcccaatca ggatttcagg accttttttg aggcgttcga tttgacgttt
     1741 ttgactggtt ccagaaataa agagttgtgc cgttaagcct agtggctgtg cccaatcctt
     1801 tgtgacttca aaaatttggc cagctaattc ggtattaggg gctaaaatga gtagttgttg
     1861 ggacttttta ggcgtcagtg ccaatagact aggaaagaca taagctaagg tcttgcccgt
     1921 cccagtaggg ctaataccaa ggaaattttt accatcaaca ataggttgaa aggcctgttc
     1981 ttggattggc gttaaatggg taaatgcaac ttggtcaagt ttttcttgcc attgaggggg
     2041 aaatttagtg atcatgcgtc ttccttttac tattgtttct atattcatta tagcattata
     2101 gtctcaattt tggtaaaata gtgagaaaga ctttttagat ttggagttta aaatgcttaa
     2161 aaaaccgatt attattggtg taactggtgg ttcaggtggc ggtaaaacaa gtgtgtcacg
     2221 cgctattttg gacagttttc caaatgctcg tattgcgatg attcaacacg attcttacta
     2281 taaagatcag tctcacatga gttttgaaga aagggtcaaa accaattatg accatcctct
     2341 agcttttgat acagatttta tgattcagca actaaaagaa ttattagctg gtagacctgt
     2401 agatattcct atctatgatt acaaaaagca tacccgcagt aatacgacct ttcgtcagga
     2461 tcctcaggat gttattattg ttgaaggtat tcttgtccta gaagatgagc gtttgcgaga
     2521 tttgatggat atcaagctct ttgtagacac agatgacgat attcgtatta ttcgtcgtat
     2581 taagcgtgac atgatggaac gtggcagaag cttagaaagt attattgatc agtacacaag
     2641 cgtggtaaag cctatgtatc atcagtttat tgagccaagt aaacgctatg ctgatattgt
     2701 tattccagag ggagttagta atgtcgttgc tattgatgtt attaatagta aaattgcgag
     2761 tattcttgga gaagtatagt ggaagtggct gagtagatta tttaaatctg ctcttttatt
     2821 gttgtgctct tcatagagaa agggatcata aaatagaaat gttattaatt tggcttggat
     2881 tactatttgt ttggaatgaa ctcgtgtttg tcatatatgc ctttgataaa agaaaagcca
     2941 taaaaaagaa acggcgtatt agtgaaagaa acttattagt gataacagtt ttgtttggag
     3001 gttttggagc attacttgca gctaaaaagt accaccataa aaccagaaag tggtactttg
     3061 tcatcacttg gtatactagt attttgttga cattactagt aacttatatc tttatgaagt
     3121 gagtcactta aaagaccctt aatcagtatt atttagtcaa ggctctttta tagtttaaaa
     3181 aagcacatca tcgtcaaggg tgttgatttt ttgaaaaaga tcaccaaaga ttaaaaggat
     3241 taatgttcct agtaaaactg tcatgccagg aatgcttgtt agaggagagt tccagatgaa
     3301 atgtagcacc agaggactta ataaccagaa aatttgttgc tgttttgaaa aaaggttaga
     3361 accctttaat aataagtatg ctccaatggt aaaaatagct gtatgtaccc aatgtgaagt
     3421 cacagcagtg ctaatacgtt caatagcagt cggtacgaga ctatctatag attttgcttg
     3481 aatcaaataa cggatatctt ctgctagttg aaagcccatg ccagaaagta aagcaacaac
     3541 taatttttct ttaagagtaa gtctaggaaa taaagtaatt actaaaatag ccgaagaagc
     3601 cttaatgggc tcttcgacaa taggggcagt taaagcatct ccccaaagct ttaaagcgtc
     3661 tttagaaggg atgatgtatg accaaaattg tcctacgaga tggttcccac aagaagctaa
     3721 aaaacctgaa atataaagtc cgctaagaca gctaacaata ataacattca ggttcatatg
     3781 aaatttttta cttaaataaa aaatagctgc tgcaaatgga attaagtaaa tgcctaatag
     3841 actaatggtt agtattagag caaaagcttc tttaaaggaa aggttgttag ctgtcagtcc
     3901 taacaattca agttcaatac catttaaaac taaagcaata aaaagaccgt atcgtaacca
     3961 tttctgttga gtgatttgtt tcacgaaaac ctcctaatat taagatgata ttaataatat
     4021 tgaaaattat atcataaaca acctcaaaaa ccattttaaa aattgactga agcgaaagat
     4081 agtcgtaaaa aatactcgaa tagacccaga tatgctataa taaaaggtat gaataagtct
     4141 aaaaaaattg agcaatacca actaatgata gcacaggcaa aagagctgtt tgcgaatgaa
     4201 tcaaatgctt tggctaattt gtcaaatgcc agcgccctgt taaacatgac actacccaat
     4261 tctgtttttg cgggatttta cctttttgat gggcaggaat taattcttgg cccttttcaa
     4321 ggtagggttt cttgcgtcca tatcaagctt ggtaaaggtg tttgtggcga atcagctcag
     4381 tctcgtcgaa ccattattat aaatgatgtg aagcagcatg ccaactatat ttcctgtgat
     4441 gcggcagcca tgagtgaaat tgttgtgcct atggtgaaag aaggccattt gattggggtg
     4501 ctggacttgg attctagcct tgtagctgat tatgatgagg ttgatcaaga atacttagag
     4561 gcctttgtgg acctatttct tgaaaagacc acgtttacct ttaacatgtt tggagttaaa
     4621 aactgatgta tcaagctctt tatcggaaat accggagcca aacgtttgac gaaatggtgg
     4681 gacaatcggt tatttccaca actttaaagc aggcagttga atctggcaag attagccatg
     4741 cttatctttt ttcaggtcct agagggactg ggaaaacaag tgcggcaaag atttttgcaa
     4801 aggccatgaa ttgtcctaac caagtcgatg gtgaaccctg taatcaatgc gatatttgcc
     4861 gagatatcac gaatggaagc ttggaagatg tgattgaaat tgatgctgcc tcgaataatg
     4921 gtgttgatga aattcgtgac attcgagaca aatcaaccta tgcgccaagt cgtgcgactt
     4981 ataaggttta tattattgat gaggttcaca tgttatcaac aggggctttt aatgcgcttt
     5041 tgaaaacttt ggaagaaccg acagaaaatg ttgtctttat cttggcaaca acggaattgc
     5101 ataaaattcc agccactatt ttatctcgtg tgcaacgctt tgaattcaaa gctattaagc
     5161 aaaaagctat tcgagagcat ttagcctggg ttttggacaa agaaggtatt gcctatgagg
     5221 tggatgcttt aaatctcatt gcaaggcgag cagaaggagg catgcgtgat gctttatcta
     5281 ttttagatca ggctttgagc ttgtcaccag ataatcaggt caccattgca attgccgaag
     5341 aaattacagg ttctatttcc atgcttgctc tgggtgacta tgttcgatat gtctcccaag
     5401 aacaggctac gcaagctctg gcagccttag agaccattta tgatagtggg aagagcatga
     5461 gccgctttgc gacagattta ttgacctatc tgcgtgattt attggtggtt aaagctggcg
     5521 gtgacaatca gcgtcagtca gctgtttttg ataccaattt gtctctctcg atagatcgta
     5581 tattccaaat gataacagtt gttactagtc atctccctga aatcaaaaag ggaacccatc
     5641 ctcggattta tgccgaaatg atgactattc agctagctaa agaagaagga gtagcgttac
     5701 catcaggttt gtcatcagat gtgacgactg aagttgaggg acttaaacgt gaacttaatc
     5761 agcttaagca agccttggca caattgcaag ccagtcccag tccctcacat gctcctgtaa
     5821 aaccagcaca ggctaaaccg aaactaacca cttacaagat tgatcgggtg aaaatactga
     5881 aaatcatgga agaaacggtt caagatagtc agcaatcacg ccaatacttg gatgccctaa
     5941 aaacagcttg gaatgaaatt ttagacagta tctcagctca agatagagcc ttactaatgg
     6001 gatcagagcc tgttctggcc aatagtgaga atgctatttt agcttttgaa gctgctttta
     6061 atgctgagca agcaatgaag cgtactgatt tgaatgcgat attcggcaac attatgagca
     6121 aagcagcagg cttctcacct aatattttgg cagtccctaa agctgatttt catcacattc
     6181 gttctgagtt tgccttacaa ttgaaaactc aaaaggcttc tgaccctaca gaagagacga
     6241 tagaagaaac ccttgagatt ccagaaggct ttgattttct agttgataaa attaatgccg
     6301 ttgaggatta aacattatta gctgttaatg aaccagtaac gctataaagg taagcctatt
     6361 gggcttacct ttagcgtttt tttatctaat ataccaagat agtttttcta gccaatcctc
     6421 taatagtaga agtgaaacca aaaaagattg atgctttctt gggtatccaa gtcagcatca
     6481 atct
//
LOCUS       DATWVB010000063         5885 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.063, whole genome shotgun sequence.
ACCESSION   DATWVB010000063 DATWVB010000000
VERSION     DATWVB010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5885
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.063"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            728..1162
                     /locus_tag="VCX65_001628"
     CDS             728..1162
                     /locus_tag="VCX65_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5054078.1"
                     /translation="MIDVSKKLKQLRIDRGIAKSRLITYLSITLRTYDRYEDGSRTPD
                     LVTLMKLSDFYQCSLDELVKGNTNDTLVDRALIVSYRDLKDKGLNDKLAHGLVKQVYD
                     TYEFEKIPQISDANRIKFIYKEDLVTLLESIVSKIQEEKKCD"
     gene            1320..1760
                     /locus_tag="VCX65_001629"
     CDS             1320..1760
                     /locus_tag="VCX65_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEP5054079.1"
                     /translation="MEHRLSMHYFQVKKEIFGVLLLSPVILLIMWGYVSSNQDDGRLT
                     QKQYYETVVNQTVNLVFYKKSCPYCKVAKKEIATQAKDSQVITYYVDTSTGEGQKLVK
                     KYHVKYAPTIVSIRKGNIQSFLYARDRGNNIIVEKEKIKEVFSQ"
     gene            1884..2276
                     /locus_tag="VCX65_001630"
     CDS             1884..2276
                     /locus_tag="VCX65_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054080.1"
                     /translation="MLNNLFIEKKGIMMSRKGVQEYDVTNVSERSIKIIKKAMYDEGT
                     GFKPIHFYGIAICEGTREFYRPTYPFVRSEEDLDNLKDFINLYETDLLTFYTHGHNYD
                     FGCFIYGIGNDGKDKFRDRWFKEGVIFY"
     gene            2369..4609
                     /locus_tag="VCX65_001631"
     CDS             2369..4609
                     /locus_tag="VCX65_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HEP5054081.1"
                     /translation="MKQTKVLTGIAVAALSTGTGLVQADDLSNTRPAKAAEVVTHTEV
                     TENQVADAKTKADEATKAVKDQEATVKAIEAEKSQAQQSLVEATTAVNDTEKLASEAT
                     PDGLTKAQEETEASQSAVTDAQAQLEAAQEAESKAQTAVDHQKETVAKASQAVNQAKA
                     ALTTSNQAADVSAAEEKVLEAQEAVTKAETQVSQAQEADAKHESDVRHAKEELDLKSQ
                     KLTEKQTTLEQVMAAIEAERLTKPVENGTYFNQRDNEWQKAYGGKTFAATGCVPSALA
                     MVFSELAKREVTPTEIADYLWHNTDEFNKHYGGTSGKGLVAATNHYGFASTHLDSQST
                     IIAALQAGHHVLAAVQNNKFSPWGSQYSHEIVLRGYSNGNTYVYDPYNRANIGWYPIA
                     NLWNEQSRDAIDTAEVGVPFFKITTQKMAQLEMAKAVANEGLDEAKQAVKQAEANVTA
                     LEQVISQTSQAKEQLAAAKANLVTAKDMLDKAKQTAKLTEQDLETKTANLKQAQEHLT
                     LKQDDLAKAQTELAAQEKSLEQLTQVLSLAQENLGRATKAVEQTKADLTQKQAYVTNL
                     KQVTKLRQESQAKVNQAKAVLSEASARLEQELETLKTLQAKEANLTAQYQAIFKAYQA
                     VLAVKHHSQLAESKAKLEAKGEEAVPVVNEVGHVTDYVSGPTQLADAVAVRTEETSSK
                     TKNTSPVSVKLMAKQGHQKALETIVTSQSSLPQTGEQVVSILSLVGLNFLGLSSFLGL
                     RKQEEK"
     gene            4779..>5885
                     /locus_tag="VCX65_001632"
     CDS             4779..>5885
                     /locus_tag="VCX65_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEP5054082.1"
                     /translation="MKQMETKGYGYFRKTKAYGLVCGITLAGALTLGTTSVSADDVTT
                     LNPATNLTTLQTPPTADQTQLAHQAGQQSGELVSEVSNTEWDNAVTTAQKAGVTVKQS
                     EKVTHDSLSSAQADLEKQTQAVTEATTKQEANTTAINQAVSENKAIDQANRDEKARVD
                     ALNTKGEADTKAKNETGQAQVDAQNKQAQAAADAMNAKLKADYEAKLTEIKQIESENE
                     AIRQRNQQASQATHQANQAAQAAYQEKLAEIERIKAENAAIRDRNAKAQQEAERQNQA
                     LQAAYEAKLAEIKQIESENAAIRKRNEQAGQTTNQTNQAAQAAYQEKLAEIERINAEN
                     AAIRDRNTKARQEAERQNQQLKTTYEAQLSAYQQA"
BASE COUNT         2149 a          951 c         1238 g         1547 t
ORIGIN      
        1 agtgcgtcag acaacacagc taagctaagt tgaataacac acataataaa acatagacac
       61 ttttattata gcgtgaaatt cttcagaagt aaagcaagtg tagtttacta taccaagttg
      121 tctgataact tttgaagttt gaattttgct tgtttaagca aaaaaagtta gatagttatt
      181 cctacctagc ttagttttac tataaaaatt gatgcaaaat agttgtggcc atgattatag
      241 taattactgt gtgttcaact aaacaagtaa agttcagacc tcaaaagcac actaaggttt
      301 atgttagtta gcctgtgttg agcaaaaaac taaaactgct actctgcaag gggtgttgac
      361 aatgattact gaaaacgtgg tgaggcggat taggtatggt attgtgggcg gtgtgttaga
      421 ctttgtctag ctaaaggata aggtggactt attcgactga gtagctcatg ttgagaaaca
      481 tagtgaaagg agtgtgcgaa gatacgagca tgcaatttaa attgaaatat agtgagaata
      541 tttttttcta tgtcgacttc tttcataagt cgactttttt gttaaaaaat aaaaatagaa
      601 atatagttta ggtattatgg ggtatcgtcc tttctctaag ctatattttt ttatttttgg
      661 aaagggtatt aagcatagta tcttttttaa aggtaaaaat ttagaatgat tgaaagggag
      721 ctgaataatg attgatgtat caaaaaaact aaaacaacta agaattgata gagggattgc
      781 taaatcgcgg ttgatcactt atttatcgat aactttaaga acttatgaca gatatgaaga
      841 tggtagtcgt actcctgatt tagtaacgtt aatgaaatta tcggattttt atcaatgctc
      901 gcttgatgaa ttagttaaag ggaacacaaa tgatacgctt gttgataggg cattgattgt
      961 ttcgtataga gatcttaaag ataagggttt aaatgataaa ttggctcatg gtctagtgaa
     1021 gcaggtctat gatacttatg aatttgagaa gattcctcaa atatctgatg ctaatagaat
     1081 taagtttatc tataaagaag atttggttac tttacttgaa agtatcgtgt caaaaataca
     1141 agaggagaag aaatgtgact agctaaaaga ttttggaggt aatgaatgtt agtttatgaa
     1201 tttattaaac aaaagatttt gtgtcatcag ctaaccaggt tgttacgaat aggtactgta
     1261 atgataactg gactctccta tagtttagat aactggaaaa agtggagggg gattgaaata
     1321 tggagcatcg attgagtatg cactattttc aagtgaaaaa agaaattttt ggggtattat
     1381 tattgagtcc cgttatttta ttgattatgt ggggctatgt ttctagcaat caagatgatg
     1441 gtcgactaac gcaaaagcaa tactatgaaa cagtggtcaa ccaaacggtt aatttagtgt
     1501 tttataaaaa gtcatgtccc tattgcaaag tagctaaaaa agaaattgct actcaagcta
     1561 aggatagtca agttattact tattatgttg atactagtac gggagaagga caaaaattgg
     1621 ttaaaaaata ccatgttaag tacgcaccta caatagtatc aattagaaaa ggaaatattc
     1681 aatcattttt gtatgctcga gatagaggca acaacattat agtagaaaaa gaaaagataa
     1741 aagaagtatt tagtcagtaa gctatgactt tatgtgtcat agctttttta tatttgttga
     1801 aaacaagggt aaaatacagt aaatctccat tcttcattct ccatttttaa accgaaaaga
     1861 ttttactctt gttttgagca agtatgctta ataatttatt tatagaaaag aaaggtatta
     1921 tgatgtctag gaaaggagta caagaatacg atgtaacaaa tgtatctgaa agaagtataa
     1981 agataattaa gaaagctatg tatgatgaag gaacaggttt taagccaatt catttttatg
     2041 gaatagctat ctgcgaaggg actagagaat tttatagacc tacttatcca tttgttagaa
     2101 gtgaagaaga tttagataac ttaaaagatt ttattaactt atatgagaca gatttgttaa
     2161 ctttttatac acatggtcat aattatgact ttggctgttt tatttatggt ataggaaatg
     2221 acggaaaaga taagttccgt gatagatggt ttaaagaagg agtcattttc tattgaattt
     2281 taaaataatt aaaaaaaaga tgacccaagg taacattaaa gtagtataat aatcttaata
     2341 aaggaagtta taggaagggc aactacttat gaaacaaaca aaagtattaa caggaatcgc
     2401 agtcgcagct ttatctacag gtacaggtct tgtgcaggca gatgatttat caaacacaag
     2461 accagctaaa gcagctgaag ttgtgacaca tacggaagtg acagaaaatc aagtggcgga
     2521 cgctaaaaca aaagctgatg aggcaacgaa agccgttaag gatcaggaag ctacggttaa
     2581 ggctattgag gcagaaaaat ctcaagcaca acaatcttta gttgaggcga caacagcagt
     2641 taatgatacc gaaaagttag ctagtgaagc gacaccagat ggtctaacaa aagcccaaga
     2701 agagactgag gctagtcaaa gcgctgttac tgatgcacaa gcacaacttg aagcagctca
     2761 agaggctgaa tcaaaagccc aaacagcagt tgaccatcag aaagaaacag tcgccaaagc
     2821 gtctcaagct gttaatcaag ccaaagcagc tctcacgaca agtaatcaag ccgctgatgt
     2881 tagtgcagca gaagaaaaag tgttagaggc tcaagaagcg gttacgaaag cagaaacaca
     2941 agttagtcag gctcaagaag cagatgctaa acatgagtct gatgtgagac atgccaaaga
     3001 agagcttgac cttaagtctc aaaaattaac agaaaaacaa acaactctag aacaagtcat
     3061 ggctgcgatt gaagcagagc gtctgactaa gccagttgaa aatggcactt actttaacca
     3121 aagagataac gagtggcaaa aagcctatgg tgggaagacc tttgcggcga caggatgtgt
     3181 gcctagtgct ttggctatgg ttttttcaga gctggctaaa agagaggtga caccgactga
     3241 gattgctgat tacttatggc ataacacaga tgagtttaat aaacattatg gtggtacaag
     3301 tggtaaagga cttgtagctg ctactaatca ttatggcttt gcttcaacac atttagatag
     3361 tcaatcaact attattgcag ctttacaagc aggtcatcat gttttggctg cagtacagaa
     3421 taataaattt agtccttggg gatcacaata tagtcatgaa attgtcttgc gtggttactc
     3481 aaatggcaat acttatgttt acgatcctta taatcgagct aacattggtt ggtaccctat
     3541 tgctaattta tggaatgaac aaagtcgtga tgctattgat acagcagagg ttggagtacc
     3601 tttctttaaa ataacaactc aaaaaatggc acaactcgaa atggcaaaag cagtagctaa
     3661 tgaaggctta gatgaagcta agcaagctgt taaacaagcg gaagcaaatg tgacagcctt
     3721 agaacaagtt atttctcaaa cctcacaagc caaagaacaa ttagctgcag ctaaggctaa
     3781 cttagtcaca gccaaagata tgctggataa ggctaaacaa acggctaaat taacagaaca
     3841 agacttagaa acgaaaacag ctaatcttaa gcaagctcaa gaacatctaa cccttaaaca
     3901 agatgaccta gctaaagctc aaacggagct agcagctcaa gagaaaagct tggaacagtt
     3961 aactcaagtg ctttcattag ctcaagaaaa tcttggccgt gctacaaaag cagttgaaca
     4021 gactaaggct gatcttaccc aaaaacaggc ttatgtgacg aatcttaagc aagtgacaaa
     4081 actgagacaa gaaagtcaag ccaaagtaaa ccaagctaag gcggttctca gtgaagcaag
     4141 tgctcgttta gaacaagaac ttgagacctt aaaaacctta caagccaaag aggctaacct
     4201 aacagcacag tatcaagcta tctttaaagc ctatcaagct gttttagctg tgaaacacca
     4261 ctcacaattg gctgaaagca aagctaagct tgaagctaag ggagaagaag ctgttcctgt
     4321 ggtgaatgaa gtgggacacg taacggatta tgtgtctggg ccaacacagt tggctgatgc
     4381 tgtagcagtg agaacagaag aaacatcatc aaaaacaaag aacacttctc ctgttagtgt
     4441 gaaattgatg gccaagcaag gtcatcaaaa ggctcttgaa actatcgtta cttcacaaag
     4501 tagccttcct cagacaggtg agcaagttgt ctctattttg agcttagtag gtttgaattt
     4561 tttaggctta agtagttttt tggggcttag gaagcaagag gaaaagtaat aaaatataga
     4621 acaagaggtc attctttaga gaatggcttt ttgattggag ttatgatgaa aatagttttt
     4681 aattggaagg caagattacc ttccttttct ttttagtaaa acatataaga cctgggatcg
     4741 tcacaaaaag caacctagaa gagagatgag aaaataacat gaaacaaatg gaaactaagg
     4801 gttatggtta ttttagaaaa acaaaggcct atggtcttgt ttgtggtatt actttagcgg
     4861 gagcgttgac gttgggtaca acaagtgttt ctgcggatga cgtaactact ttaaacccag
     4921 cgactaactt aacaacgcta caaacacctc caacagctga tcaaacacag ctagctcatc
     4981 aagctggcca gcagtcaggg gagttggtat cagaggtgag caataccgaa tgggataatg
     5041 ctgtcacaac agctcaaaaa gcaggtgtta ctgtcaaaca gtctgagaag gtcacacatg
     5101 atagcttatc atctgcgcaa gccgatttag agaaacaaac tcaagctgtc acagaagcga
     5161 caactaaaca agaagccaac acaacagcta ttaatcaagc agtttcggaa aataaagcga
     5221 ttgatcaagc taatcgtgat gaaaaagcta gagttgacgc tcttaatact aaaggggaag
     5281 ctgataccaa agctaaaaat gaaactggtc aagcccaagt agatgcacaa aataaacaag
     5341 cccaagcagc agctgatgcc atgaatgcca aattaaaggc agactatgag gccaagttaa
     5401 cagaaatcaa gcagattgaa tcagaaaatg aagctatccg tcagcgcaac caacaagcta
     5461 gtcaagcgac tcatcaagcc aatcaagcag cccaagctgc ctatcaagaa aagctagcag
     5521 agattgagcg catcaaagcc gaaaatgctg ccattcgcga tcgtaatgct aaggctcaac
     5581 aagaagcaga gcgtcaaaac caagcgctcc aagcagctta tgaagcaaaa ttggcagaaa
     5641 tcaagcagat tgaatcagag aatgctgcta ttcgtaagcg taatgaacaa gcaggtcaaa
     5701 cgacgaatca aacgaatcaa gcggctcaag ctgcctatca agaaaagcta gcagagattg
     5761 agcgtattaa cgccgagaat gccgccattc gtgatcgcaa cactaaagct cgacaagaag
     5821 cagaacgtca aaaccaacag ttaaaaacta cttatgaagc tcaattatca gcctaccaac
     5881 aagca
//
LOCUS       DATWVB010000064         5567 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.064, whole genome shotgun sequence.
ACCESSION   DATWVB010000064 DATWVB010000000
VERSION     DATWVB010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5567
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.064"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1176
                     /locus_tag="VCX65_001633"
     CDS             <1..1176
                     /locus_tag="VCX65_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEP5054083.1"
                     /translation="TAMLTVGFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESGGD
                     ISLKFTQLGAETNAFTTFNQTSFFFSTASKFQENLELLQYFVLSANITDESVSREKKI
                     IGQEIDMYQDDADYRAYSGILQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQ
                     PTNMSLFIVGDIDIDETFLAIQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSVDMDVTI
                     AKLVVGFRGYLTLTQHSLLTYRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVE
                     IHHHFQFVLISLDTPEPIAMSNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLD
                     SIEHLTHQFSLYLSDSDKETYFDIPKIIERLTLKDVVTIGKAFFEKADASDFTVFPK"
     gene            1226..2251
                     /locus_tag="VCX65_001634"
     CDS             1226..2251
                     /locus_tag="VCX65_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP5054084.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGYGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     NVSRMRRNSTDSRSKTSLFPIAILGTVAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTKGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            2265..2807
                     /gene="pgsA"
                     /locus_tag="VCX65_001635"
     CDS             2265..2807
                     /gene="pgsA"
                     /locus_tag="VCX65_001635"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEP5054085.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVASNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMPGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            2809..3648
                     /locus_tag="VCX65_001636"
     CDS             2809..3648
                     /locus_tag="VCX65_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEP5054086.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPVDYGYLTEKELENQLCQLI
                     SKM"
     gene            3624..4466
                     /locus_tag="VCX65_001637"
     CDS             3624..4466
                     /locus_tag="VCX65_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEP5054087.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELKEV
                     LKHG"
     gene            4459..5259
                     /locus_tag="VCX65_001638"
     CDS             4459..5259
                     /locus_tag="VCX65_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEP5054088.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
BASE COUNT         1805 a          889 c         1030 g         1843 t
ORIGIN      
        1 acagctatgt tgacagtagg tttcggttct cttgacaata agttgacagt cgatgacgaa
       61 tcacgagatg ctccagcagg tattgcacac tttttagaac ataaactctt tgaagatgaa
      121 tcaggtggag atatttcatt aaagtttaca cagctaggag cagagacaaa tgcctttaca
      181 actttcaacc aaacgagttt cttcttttca acagctagta aatttcagga aaatttggaa
      241 ctccttcaat attttgttct ttctgctaat ataacagatg aatctgttag tagagaaaaa
      301 aaaataatcg ggcaagaaat tgatatgtat caagatgatg ctgactaccg tgcatatagt
      361 ggaatccttc agaacttatt tccaaaaaca agtttagcta atgatattgc tggctcaaaa
      421 gcatccattc aaaagatcac gaaaatatta ttggaaacgc atcatactta tttttaccaa
      481 cctactaata tgagtctatt cattgtcggt gatattgata ttgacgaaac ttttttagct
      541 attcaaaggt ttcaaaccac attatcctat ccagatagaa aaagggtaac tgttgatcct
      601 ttacactact atcctgtcat taaatcatct tctgttgaca tggatgttac tattgccaag
      661 ctggttgttg gttttcgagg gtatctgacc ttaactcagc attcactatt aacgtatcgt
      721 attgccttga agctattttt atcaatgctt ataggttgga cttctaaaat ctatcatacg
      781 ctatatgaag atggtaaaat agacgattca tttgatgtgg atgttgaaat tcatcatcat
      841 tttcaatttg tattaatatc acttgataca ccagagccta tcgcaatgtc taactatatc
      901 cgtcaaaaat tagccactat aaagatatca aaagagttta caaatgagca cttaaatcta
      961 ttaaaaaaag aaatgtatgg tgactttatt cagagtttag actctataga acatttaacc
     1021 catcagttca gtctatacct gtctgattct gataaagaaa catattttga tattccaaaa
     1081 attatagaaa gactcactct aaaagatgtt gttacaattg gaaaagcatt ttttgaaaaa
     1141 gctgatgctt cagacttcac agtcttccca aaatagatga aaatctgtta taataggatt
     1201 actatattat ttttgaggta cctgtatgag tgaaaaaagt cttggtgaag tgttaagaga
     1261 atcgcgtgtt ggaaaaaata tcacactaga tgatatagaa ttgaagacag ggatttcttc
     1321 ccattacttg ctggcaatgg aattggatca gtttaaaatt attccggaag aaaaatttga
     1381 tcaattttta aaagaatatg ctgacattgt tgagttagat ttcaatactt taaaaagacg
     1441 ataccgttat caagttaatt ccaaaaaaga cagtgatata aaatctgtaa ctgagattgt
     1501 tgaagagaag ttaagtaaga aacgattaca agagaagttg ttatcacatc agagcatggg
     1561 gtatggtcaa ccgttagaag tttctaaaaa caaagaaacc ttagttatcc ctgtaaagac
     1621 tgttggttta gatagcaaat cgccactaaa aacgatatcg cctgttagcc aatttaaatc
     1681 agataacagg ttaattccta aaaaaaatgt gtcacgtatg aggcgaaata gcactgacag
     1741 tcgttctaaa acgtcactat ttcccatagc tatattagga acggttgctt ttgcaattat
     1801 cagtgttatc attttaggtg tttggcaaca attcgaaaag agtcaaagag ctaaagaagc
     1861 tgaagttgct ttgcttaaag cctctgagca gtctactaac ggtttaaaaa ataattcaaa
     1921 tgatcgcaaa actcaagtca caactgaggg gtcgggtaat tatttaatag cgactgttac
     1981 taaatctaaa gagaccgttg atatcagtgt gtctttaact gaggcacaaa gtagttggat
     2041 ttctctaaca aattcagaaa ttggtgaagg tggtataaca ttgactcaag actcgccaac
     2101 ttatacagcg actttacctg cagaaataac agaatcattg ttgacacttg gtgtgacaaa
     2161 aggtgtatct gtaacaattg atggacaacc tgttgatcta tcacctttaa caagtactga
     2221 cttaagttat atcacgttta agatccaata attaaggtag actaatgata aaaaaagaaa
     2281 atattcctaa tctattaact cttgttcgaa tcgcaatgat tcctttcttt ctttttatta
     2341 cttcctcatc taataaggtg gggtggcata tttttgcagc tgtgattttt gcaattgcca
     2401 gttttaccga ttatctagat gggtatcttg cgcgtaagtg gcatgtagcc agtaattttg
     2461 gaaagtttgc cgatcctcta gcagataaga tgcttgtcat gagtgccttt atcatgttag
     2521 ttggacttgg cttagttcct gcgtgggtgt cagctgttat tatttgccga gaattggcag
     2581 taactggtct tcgattacta cttgttgaaa ccggaggaaa ggtccttgca gctgctatgc
     2641 cgggaaaaat caaaacagcg acacaaatgt tgtctattat tttattactt tgccattgga
     2701 tattcctagg aaacgtctta ctctatattg ctcttttttt cactatttat tctggatatg
     2761 attattttaa aggagcaagc tttcttttta aggatacgtt taaataacat gtcagctatt
     2821 attgaactta aaaaagttac atttaattac cataaagacc aagaaaaacc aacattagat
     2881 ggcgtatcgt ttcatgtgaa acaaggtgag tggctgtcta tcattggcca taacggatct
     2941 ggtaaatcaa cgactattcg attaattgat ggattattgg aaccagaatc agggtctatt
     3001 attgttgatg gagatctact aaccataact aatgtttggg aaattcgtca taaaattggt
     3061 atggtctttc aaaaccctga taatcagttt gttggagcaa ctgttgaaga tgatgttgct
     3121 tttgggcttg aaaataaagg tattgcacat gaagatataa aagagagggt taatcatgct
     3181 ttagagttag tcggcatgca gaactttaaa gaaaaagaac cagcccgttt atctggtggc
     3241 caaaaacagc gcgtagctat tgcaggtgca gttgctatga agcctaaaat tattatttta
     3301 gatgaagcta ctagtatgct tgaccctaaa ggacgattag agttaatcaa aactataaaa
     3361 aacatccgtg acgactacca gctgactgtt atttccatta ctcatgactt agatgaagtt
     3421 gctcttagtg atagagtttt agtgatgaaa gatggtcaag tggaatcaac atcaacacca
     3481 gaacaattat ttgcaagagg ggatgaacta ctccaattag gtcttgatat cccttttaca
     3541 acatctgttg tacagatgct tcaagaagaa ggttatcctg ttgactatgg atatctcaca
     3601 gaaaaggaat tagaaaatca gttatgtcaa ttaatctcca aaatgtaagt tatacttatc
     3661 aagcagggac tccttttgaa gggcgtgccc tttttaacat taatttagat attttagatg
     3721 gttcttatac ggcttttatc ggacatactg gatccgggaa atcgaccatt atgcaattgc
     3781 taaatggttt acacgttccg acaacgggaa ttgtcagcgt agataaacaa gatataacga
     3841 atcactctaa aaataaagag attaaatcta ttcgaaaaca tgtaggatta gtttttcaat
     3901 ttccagaaag tcaactattt gaagagacag ttttgaaaga tgttgctttt ggccctcaaa
     3961 attttggggt ctctccggag gaagcagaag ctttagcgcg tgaaaaacta gctcttgttg
     4021 ggatttcaga aaatcttttt gaaaagaatc catttgaact ctcagggggt caaatgcgtc
     4081 gtgttgctat tgcgggtatc cttgctatgc agccaaaggt tttagtttta gatgaaccga
     4141 ctgctggtct tgatcctaaa gggcgtaaag aattaatgac tatttttaaa aagttacacc
     4201 aatctggcat gactattgtt ttagtaaccc atctgatgga tgatgtggcc aattacgcag
     4261 attttgtata tgttcttgac aaaggtaaaa ttattttatc aggaaaaccc aaaacaattt
     4321 ttcaacaagt cagtttgctt gagaaaaaac agttaggagt tcctaaggtg actaaacttg
     4381 ctcaaaggct tgttgataga ggaataccta tctcttcttt gcctattacc ttagaggagc
     4441 taaaagaggt actaaaacat ggataagctg attcttggtc gttatattcc cggagattct
     4501 ctcattcatc gtcttgaccc aagaagtaaa ttattagcga tgattattta tattgtcatt
     4561 atcttttggg ctaacaatgt tgtgacaaat ttgttgatgt tgacttttac tttagcagtt
     4621 gtttttttgt caaaaatcaa gttgtctttc tttttaaatg gggttaaacc aatgattggt
     4681 attatcctct tcacgacttt atttcagatg tttttctcac aaggaggaaa agtaattttt
     4741 agttggtggt tcattagcat aactgattta ggattgagcc aagctatttt aatttttatg
     4801 cgtttcgttc taattatttt cttttcaacg ctgttaacgt tgacgacaac acctttaagc
     4861 ctatctgatg cagttgaatc attattaaaa cctttaacaa gatttaaagt tccagctcac
     4921 gagatcggac taatgctttc tttaagttta cgttttgtgc ctactttaat ggatgatacc
     4981 acgcgtatta tgaatgcaca aagggcccgt ggagttgatt ttggagaggg aaatttaatt
     5041 caaaaagtta aatctattat tcctatttta atccctcttt tcgcttcaag ctttaaaaga
     5101 gccgacgcat tagctattgc tatggaagct agaggttatc agggaggaga agggcgaact
     5161 aaatatcgtc aattagactg gcagctaaaa gatagtttag ctattggaat agtttcttta
     5221 ttgggtttgc tacttttttt cttgaaaacc tctttgtaat attttttagc acaaaacttt
     5281 tctttattag taagaagtga attgtacctc aaaagttaga tacaacatct aatgattgag
     5341 gtacttttct tcatttgagg aattgaaaac cgctatctca actatattaa tcctcccaat
     5401 aataacaaat cgaacgaaat ctaaaaggac tgagtcctgt tcaatacaga actaaattat
     5461 tagtttaatg atattatccc gctttttaat gttgctaaga agaagagttt tatgattttt
     5521 tacaacttct tataatatca atgtagttgt aatattttta atatatc
//
LOCUS       DATWVB010000065         5169 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.065, whole genome shotgun sequence.
ACCESSION   DATWVB010000065 DATWVB010000000
VERSION     DATWVB010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5169
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.065"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..873
                     /locus_tag="VCX65_001639"
     CDS             <1..873
                     /locus_tag="VCX65_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP5054089.1"
                     /translation="NLRKKHNITQSELGNAGQVSQVESGKRPITSSMLVYLNALTASS
                     YTYIVFGELDEFIENLFHYFFSSILYRDLEAVDENLYSFMSDDLISIQSSCLSIVKTF
                     ANFNIQRKRFMISTETEMDTFHKKDDIDVWVGGKSYNPARSFRNNPINELTVIDFEEM
                     ADILLLMLRDNLIRSFEINVCNTLFELDKNGEPTTFNLDKIDSIINKWWSENVSTEII
                     PNLIKKLRENPLFNIGFMVNDILERMYKEDIPKSYLTSVPLVISKKARSTLSIKSNGS
                     QKIDKSKFAQILSL"
     gene            939..1691
                     /locus_tag="VCX65_001640"
     CDS             939..1691
                     /locus_tag="VCX65_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEP5054090.1"
                     /translation="MAIPDLDKFSSNLQQGKIPVIKHFELNLDKGSHWAIAGNSGSGK
                     PYALTYFLSVLKPMSGLIIIDPKFDTPSQWARENKIAVIHPVENHSKSDFVSQVNEQL
                     NQCATLIQKRQAILYDNPNHQFTHLTIVIDEVLALSEGVNKNIKEAFFSLLSQIALLG
                     HATKIHLFLGSQRFDHNTIPISVREQLNVLLQIGNINQKTTQFLFPDLDPEGIVIPTG
                     HGTGIIQVVDNEHSYQVLPLLCPTYYTKRGIL"
     gene            1688..2290
                     /locus_tag="VCX65_001641"
     CDS             1688..2290
                     /locus_tag="VCX65_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054091.1"
                     /translation="MTTKTYFMRSFNLILYLLLIAPICYVFGWLFNLVSVQLSTVTFV
                     NLDTVKNVTDTISSVCYGFALISLLLALLSGLKMIQRLNTDSLGNYCQSIYRTFLLRH
                     FLFQRERVQKVSNFEHQTVTTINPIHNGFNRAVRKCIVDIRKDAITVFLKVPRDQQGQ
                     KILKDTGVQLKEEIVIQHTDYYFSSPVRVRNQLWFIGQKR"
     gene            complement(2766..3047)
                     /locus_tag="VCX65_001642"
     CDS             complement(2766..3047)
                     /locus_tag="VCX65_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP5054092.1"
                     /translation="MLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGT
                     LLIAISIYPIMSWLGWWGYGPVAILWLIIMRIALRIERFKKTYDVQTYR"
     gene            complement(3054..3098)
                     /locus_tag="VCX65_001643"
                     /pseudo
     CDS             complement(3054..3098)
                     /locus_tag="VCX65_001643"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3501..4343
                     /locus_tag="VCX65_001644"
     CDS             3501..4343
                     /locus_tag="VCX65_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEP5054093.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     MRDNFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVSVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKADWLWLVLTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMAFVLFALGIWLGLWMSQLE
                     EKYK"
     gene            complement(4390..5031)
                     /locus_tag="VCX65_001645"
     CDS             complement(4390..5031)
                     /locus_tag="VCX65_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEP5054094.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWKSIQPNEEVDKVFIVPLRQLLFTDPVYYRLEATPIETTDFPFDRIRNGKYY
                     QFSQEYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIAKKNPSDIENSKGR"
BASE COUNT         1607 a          965 c          859 g         1738 t
ORIGIN      
        1 aatttaagaa aaaaacacaa tattacacaa agcgaactag gcaatgcagg tcaagttagt
       61 caagttgaaa gtggtaagcg accaattacg agttcgatgt tagtttattt aaatgctcta
      121 accgcttcga gctatacgta tatcgttttt ggagagttag atgagtttat tgagaatctg
      181 tttcattatt ttttcagttc tattttatat agagatttag aggctgtaga tgaaaaccta
      241 tattctttca tgagtgatga tttaatttca atccaatcaa gttgtctaag tattgtcaag
      301 acatttgcaa atttcaatat tcaaagaaaa agatttatga tttctactga aactgaaatg
      361 gatacttttc acaagaaaga tgacattgac gtatgggttg gtggaaaaag ttataacccc
      421 gctaggagtt ttaggaataa tccaataaat gaattaactg ttattgattt tgaagaaatg
      481 gctgatattc ttttgttgat gttgagagat aatctaatta ggtcgtttga aattaatgtc
      541 tgcaacacac tgttcgaatt agataaaaat ggtgaaccga caacatttaa tctagataaa
      601 attgactcaa taatcaataa gtggtggtct gagaatgtct caacagagat aatacccaac
      661 ctcataaaaa aacttagaga aaatcccttg tttaatatcg gatttatggt aaatgatata
      721 ttagaacgaa tgtataaaga ggacatacca aagtcttacc ttacttctgt tccattagtt
      781 atttccaaaa aagcaaggtc aactttatcg attaagtcaa acggaagtca aaaaatagat
      841 aaatcaaaat ttgcacagat tttgtccctt tagagacgga tgacttacac attcaacgtg
      901 gattattctt cccttggaga aaggggattt cagaacgctt ggcgattcct gatttagata
      961 aattttcatc taacttacaa caggggaaaa ttcctgtcat aaagcacttc gaactcaatt
     1021 tagataaggg gagtcactgg gctattgctg gaaattcagg ttctgggaaa ccgtacgctc
     1081 tcacttactt cttgagtgtc ctgaaaccta tgtccggcct aattatcatt gacccaaaat
     1141 tcgatacccc tagccaatgg gcaagagaaa ataaaattgc cgttatccac ccagtagaaa
     1201 accattcaaa atctgatttc gtttcacaag tcaatgaaca attaaaccag tgtgcaactc
     1261 tcattcagaa acgacaagct atcttgtatg ataatcccaa tcatcaattt acccatctaa
     1321 ctattgttat tgatgaagtc ctcgctctat cagagggagt caataagaat atcaaagaag
     1381 cttttttctc cctactatca caaattgcct tgttgggaca tgctactaaa atccatctat
     1441 tcttgggaag ccagcgtttt gaccataaca ctattcccat ttcagtgagg gaacagctaa
     1501 acgtattatt gcaaattgga aatatcaatc agaaaaccac tcaattctta tttccagacc
     1561 tagatccaga ggggattgtc attccaacag gacacggaac aggtatcatt caagttgtcg
     1621 ataatgaaca ctcctatcaa gttctaccct tactctgtcc aacctactat actaagcgag
     1681 gtatcctatg accactaaaa cctacttcat gagaagcttc aatctcatat tatacttact
     1741 gcttattgct ccaatctgct atgtgttcgg ttggctgttc aatcttgttt cagttcaatt
     1801 atctaccgtc acatttgtca atctggatac ggttaaaaac gttactgata ccattagttc
     1861 tgtatgttat ggattcgctc ttatttcttt acttctagcc ttattatctg gattaaagat
     1921 gatacaacgc ttgaatacag atagccttgg gaactactgc caatctattt atcgcacctt
     1981 tctattaaga cacttccttt tccagcgtga acgagtacag aaggtaagca actttgaaca
     2041 ccagaccgtt accactatca atccaatcca taacgggttt aaccgagctg tacgtaagtg
     2101 tatcgtagat atacgaaaag atgccattac tgtatttcta aaagttccta gagaccaaca
     2161 ggggcaaaaa atcctaaagg atacgggagt acaactgaaa gaagagattg tcatccaaca
     2221 cacagactat tatttctctt ctcctgttcg agttcgtaac caattgtggt ttattggtca
     2281 aaagcgttaa ttccttgggg ctgtggcttg cgttaagcaa aagccagaca gccccttttt
     2341 tatattctta tctatcatga cctattgggg ttactacgac aacgaaagtt agaagctgtg
     2401 ggtatttatt tatcttgaaa agattgctga actaacgcaa taactactct accattcact
     2461 ctacctttta ttaagcaact atcaataaat attgatacaa taaggtttat aacagctaaa
     2521 atagaaaata cttaaccttt acagaagtaa aataattgag atgagaaaag cctatgaaat
     2581 gaacgtttca aaggcttttt tcgtgtttaa aaaaacaaat gaaaaaacaa aatagagagt
     2641 agggttatta acactgtcaa tcctgtgtac gcaataacaa tccatgcttt ttgataagga
     2701 tattttgctt tttctttaat cttatcaatc tgatctaagc tctcaccctt tgctataact
     2761 tcaagttatc ggtaagtctg aacatcatat gtctttttaa atcgctcaat tcttaaggcg
     2821 atacgcatga ttatcaacca taagatagca accggaccat atccccacca acctaaccaa
     2881 gacattatag gataaatact gatagcaatt aggagtgtcc caaataacat aatatgcgta
     2941 ttcctatcac attgtttaat ctcctcatcc ttaataatta aagtcatttt tgggatatct
     3001 tctgctatta gttgctctaa aggaacctgt aaggacttac ttaacatcaa aagattttgc
     3061 aggtctggat agcttttacc gttttcccag tttgagatag tcttcttgaa acatacatca
     3121 tttcagcaag ctcttcttgt gacatctgta atttttttca ataataagat aactggtttt
     3181 taaagcccat aataaatctc ctttttaata gctactataa tccttcttca ataagtttac
     3241 tatcaaaagt ctttgaccta agcttttttt cgtttatctt tttaataatt atcgtaaggt
     3301 ttacagtctt tgtaaatttt atttacaact ttgacaatca aacttgactt gatcacaaag
     3361 acatggtgtt taaggaaaat atcttcaaaa ttgaatgtat tatttattag gaacaattat
     3421 tttagtaggg atatgcagct ttgtgtcagc aattctttaa atttatgata caataaaatc
     3481 attcttttca ggaggcaaca atggtttcat ttatttcaag agtttttaaa ggcatgatta
     3541 ttgcactagg ttttatttta cctggtgtat ccggtggtgt tctcgcagcc attttaggaa
     3601 tctatgagcg aatgatttcc tttttagctc atatgaggga taactttatt gaaaatgtct
     3661 tatttttctt accagtagga attggtggta ttttaggtat tgctctcttt tctttccccg
     3721 ttgagttttt gcttaagcac tatcaagtta gcgtcttatg gggatttgct ggcgctattg
     3781 tcggcactat tcctagtctg attaaggagt caaccaagca gtctcaaaga gacaaagctg
     3841 actggctatg gctagtcctt acctttgtta tttcaggact aggtctttac ttcttaaatg
     3901 acttaatcgg taccttacca gctaactttt taacctttat tttagcaggt gccttaattg
     3961 ctttaggagt actggtccct ggactaagcc cgtcaaatct cttacttatc ttaggactct
     4021 atggtcctat gttaataggg ttcaaatctt tggatttatt agggactttc ttacctattg
     4081 ctatcggagg agtcctagcc atcttggctt tttctaaaag tatggattat gctttacagc
     4141 accatcattc aaaagtttac cactttatca ttggtattgt attatccagc acgctattaa
     4201 ttcttattcc aaatagtagt agtcccgaat ccatttccta cagtcatgca ggtatcttaa
     4261 cctggcttat ggcctttgtg ttatttgctc ttggtatttg gctcggactt tggatgagtc
     4321 aattagaaga aaaatacaaa taacctttac agtttgttga caaaaagttg acgccaacaa
     4381 actagtgctc tatctcccct tagaattttc aatatctgag gggtttttct ttgcaattga
     4441 ttcatcattt agaatatcgg ttaaacactt agtaaactgg gcagtcattc cccatatggt
     4501 ttcttctaga ttttcataaa acggaatact acggtactct tgactaaatt ggtagtattt
     4561 cccattacga atacggtcaa aaggaaaatc cgttgtctca ataggagtgg cttctaaacg
     4621 ataatagaca ggatcagtga aaagtagctg acgtaaaggt actataaaga ccttgtcaac
     4681 ttcttcgtta ggctgtatgc ttttccagtc atcaacgact aattgaccaa cgaaacaatg
     4741 aatagttcta gaagactgta ctaaataatc aatttcaccc catagctgga tctgggacgc
     4801 atcaacagtc aattcctcaa ctgtttctcg gatagcagct tcttgaagtg tctcctgatt
     4861 ttctacttgt ccccctggga aagaaacttc ccccggttgt gaaatatgct gacttctgac
     4921 ttcatataag acatgccagt catcattgac aagaataaga ggtaaaaata cggcgtaccg
     4981 cttctcctct cctagtggtt ttgcctgata ctgttttaat aagtccttca tagccttccc
     5041 taatttctct ttccgttaat cttatcttca tcataaccaa tcctagcttt ttggtcaatt
     5101 tattactcct agttagtgat ttttgatata tatgttattt ttttatatat aaaatattga
     5161 catatcaaa
//
LOCUS       DATWVB010000066         5129 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.066, whole genome shotgun sequence.
ACCESSION   DATWVB010000066 DATWVB010000000
VERSION     DATWVB010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5129
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.066"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(102..635)
                     /locus_tag="VCX65_001646"
     CDS             complement(102..635)
                     /locus_tag="VCX65_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP5054095.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFSTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
     gene            770..3043
                     /locus_tag="VCX65_001647"
     CDS             770..3043
                     /locus_tag="VCX65_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEP5054096.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGNDMVDKMSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNPEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLAALTGASQQFQQGT
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNTELSTLQPPNLNADELGNSLGAIAQAAKQVIA
                     EETAAQNEQLSALQATSVYQSLTAEQQGELAAALSQSDKSQTVSAAQTILSSVQTLST
                     GLQTLSQGNSLAQLDQLKAAVSQIASQSNQALPGASSALSELSMGLSKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTVIGSGVIKLSEGANALSSKSGELLDGSHQLSEGATKLADS
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWDWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            complement(3160..4233)
                     /locus_tag="VCX65_001648"
     CDS             complement(3160..4233)
                     /locus_tag="VCX65_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEP5054097.1"
                     /translation="MKNISRKCFMTSVVCIVLGAILLGAGYATGGLQDIKHQTAPKKV
                     IQTFDHVTALDIDTNFSTITVETGPVKKPTVTYYTHSKFIDPLEIKIENETLHISEKP
                     RDVIITGGIELIGFGLNKSDRNHNYRTTTITLPKGTSLKELKGSSMPQATISDLTVQD
                     LEFSGGLTLLNTRIKKGKVFGTFNATDSLLANLELKADYSLSSLTNSSLENGTISLGH
                     GQLTTKNTNLKSVTIQSLSPGGVETEETSLENVTFTVTSEQENEETNDNGAIFTAHAL
                     TLKGTNTISGGNVAVDITLTDPKTTAYKTKTEDGKILLGSQLTPAKIGKESTSDVISY
                     VAENKAATGNLTVNLNKGDITIK"
     gene            complement(4230..4817)
                     /locus_tag="VCX65_001649"
     CDS             complement(4230..4817)
                     /locus_tag="VCX65_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEP5054098.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEALEYYIEYFDEAGPDKESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIACLMLGLTAIFAAYIFGLAGILVAGVTLFESLTLIGSSIPAQAMGIGSALLCFG
                     GGLLIWIIATALLRFSGRAFVAFIKWISHKKGAQA"
     gene            complement(4804..>5129)
                     /locus_tag="VCX65_001650"
     CDS             complement(4804..>5129)
                     /locus_tag="VCX65_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEP5054099.1"
                     /translation="YFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLYP
                     ILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGSL
                     RHDKD"
BASE COUNT         1528 a          964 c         1010 g         1627 t
ORIGIN      
        1 ataacaaatt tatcctgatc ccttcatttt actatggctt ctaaaaaagt tatcactaag
       61 gctgatgact tgtaaaatga tactttcgta agggttatta tttaggtact cgtaagcatt
      121 ttgagaacga attgtgtcat ttcttgaggt gattcttttt tacctttagc aatccaactt
      181 tgacagacac caaaaaaagc atgggctaag tagatacttt ggtattcttt ttccgtttga
      241 gataactctt cggtactgaa cttgtcctgt aaatcagtag tgatgagtag gcgaacttta
      301 ttgatgataa aggcctgtat ttctttagta ccgttagcag acaaaaggga agagagaagc
      361 tgttctcttt ggagaaattc aaatacttca aggaaggctt gttctttatt ttgatatttt
      421 ttctcaaaaa tatattctaa tttgtgaaaa aaggtttgct gataatagtc aatcatttca
      481 tatttatctt tatagtgtgt gtaaaaacta gagcgactaa ttccagctct tttagataat
      541 ttaactgtgg taatatcgtc aaaactttcg gtttttagta acataaccat tgcttttaaa
      601 attgcttgct tcgtattttc tttacggttg accatctacc atctctcctt ttgaacactt
      661 ttagacgtaa tgtccaaaag tgaatttttt tctcttgtaa atttaaattt aaattgtata
      721 atatatttta tcataatttt tgaacagtat gtccatttta ggagaaaata tgttagaaga
      781 attgaaaaca cttattaaaa atccaaaatt aatgattaca atgattggtg tggccctagt
      841 gcctgcctta tataatttat cctttctagg ctcaatgtgg gatccttatg gtcgggtcaa
      901 tgaccttccc attgctgttg ttaatcatga taagcctgca aagagagctg ataagtcatt
      961 gacaattggg aatgatatgg tggacaagat gtctaaaagt aaagatttag agtatcattt
     1021 tgtctcagct aagcaagctc aagagggact taaagaaggt gattattata tggttattac
     1081 tttacccgaa gatctttctc aacgggcagc aaccttatta aatcccgaac cccaaaaatt
     1141 aactatccgt taccaaacga gtaaaggaca tggaatggtc gctgctaaga tgggggaaac
     1201 agcgatggct aagctgaaag agtctgtttc gcaaaacatt acgaagactt atacctcagc
     1261 agtttttagc agtatgacag acctccaatc aggattaaaa gaagcctcag ctggaagtca
     1321 agcacttgct tcaggagcga agaccgctca ggcggggagt caaacacttt cgacgaactt
     1381 agcagcctta acgggtgcta gccaacagtt tcaacaaggt actggtcgat tgacatcagg
     1441 tttgactacc tatacagatg gtgtcaacca agtcaagaat gggttaggaa cattatcaac
     1501 ggacatcccc aattatctga acggggtttc taggttatcc cagggagctt ctcagcttaa
     1561 tcagggtctt tcacagttga cacaagcaac aacactttct gacgagaaag ctaagggaat
     1621 tcaatcctta attgtaggac taccagtcct aaatcaaggc attcagcaac taaatacaga
     1681 gctatcaaca ttgcaacccc ctaaccttaa tgctgatgag ttaggtaata gcttaggagc
     1741 tatcgctcaa gctgccaaac aagttattgc tgaagagact gccgctcaga atgaacaact
     1801 atcggctctc caagccacta gtgtttatca atcattaact gctgaacaac aaggagagtt
     1861 agctgcggcc ctcagtcaat ctgataaaag tcaaaccgta tctgcagccc aaactatttt
     1921 aagttctgtt caaacactgt caacaggttt acaaactctg tcccaaggaa atagtttagc
     1981 tcaattagac cagcttaaag cagctgtttc acagattgcg agtcagtcta accaggcttt
     2041 acctggagcg agttctgcat tatctgagtt gtcaatgggg ttatcaaagg taaatggtag
     2101 cttaaatcaa caagttctac caggaagtaa tcaattgaca acaggattag cacaattaaa
     2161 caggtataat actgtcattg gttctggggt aataaaactc tcagaaggtg ccaatgcctt
     2221 gtcatccaag tccggagaat tactagatgg tagccatcaa ttatcagagg gtgctactaa
     2281 actagctgat agtagttctc aattgagtca gggtggtcat caattaacga gcggattgac
     2341 tgaattatca acaggattat caaccttaaa tggttcctta gccaaagcct ctcagcagtt
     2401 atcgcttgtt tctgtgactg ataaaaatgc taaagctgtc gcaaaacctc ttgtgttaaa
     2461 tgagaaagac aaagatggtg ttaagacgaa tgggatcggg atggcacctt atatgattgc
     2521 tgtttctcta atggttgtgg ccctttcaac caacgtcatt tttgctaatt ctttatctgg
     2581 tcgtccggtc aaagataaat gggattgggc taaacaaaaa tttgttatta atggttttat
     2641 ttcgactatg ggatccattg ttctctactt agctattcaa ttattagggt ttgaagcccg
     2701 ttatggtatg gaaaccttag gatttattat gctaagtggt tggacgttta tggctcttgt
     2761 cacagctttg gtcggttggg atgatcgata tggctctttt gcttctttgg tcatgttatt
     2821 acttcaggtt ggctcttcag gtggctctta ccccattgag ttaagtggag cattcttcca
     2881 aaagttacat cctttcttac caatgactta tgtggtatct ggtttacgac aaaccatttc
     2941 attatcaggt catattggag tagaagtgaa agtcttaact ggtttcttac tggcatttat
     3001 ggtattagca ctactcattt atcgtcccaa gaaaacagtc taaataaaat aacctcaaaa
     3061 aaaaacagca tctaaggcag ttacactaga tgctgttttt tgtcttattt tgacaataac
     3121 ttgacaattt ctgtcaagtt ttttattgtc ttgttaagat tatttgatag taatgtctcc
     3181 cttattgaga ttaaccgtta aatttccagt agctgcttta ttctcagcca cataagaaat
     3241 aacatctgaa gttgattcct taccaatctt agctggtgtc agctgtgatc caagtaagat
     3301 tttaccatct tcggtttttg tcttataggc ggtcgtcttt ggatcggtca aagttatgtc
     3361 aacagcaaca ttaccaccac taatagtatt agtgccttta agggtaagag catgagcagt
     3421 gaatatagca ccattatcat tggtttcctc gttttcttgc tcactagtaa cagtgaaagt
     3481 cacattttca aggcttgttt cttcagtttc aaccccacca ggagatagag attggatggt
     3541 gacagattta agattagtat tttttgtggt taattgtcca tgccctaagc taatcgtccc
     3601 attttctaaa ctagaattcg taaggcttga caacgaatag tcggctttca actcaagatt
     3661 ggctaacaag ctatcagtag cgttaaatgt tccaaaaacc ttccctttct ttattctagt
     3721 atttagaagt gtcagaccac cactgaactc aaggtcttga accgttaaat ccgatatagt
     3781 ggcttgaggc atgcttgagc ctttgagctc tttaagactg gtaccttttg gaagcgttat
     3841 ggtagtggtt cggtagttgt ggttgcggtc acttttattt aatccaaacc cgatcagttc
     3901 aatacctccg gtgatgatga catctctggg tttttcagaa atatgaagtg tctcgttctc
     3961 tattttaatt tctaaaggat caataaattt agaatgtgtg taataggtaa cggttggttt
     4021 tttgacaggc cctgtttcta ctgtaatagt tgaaaaattg gtatcaatat caagagctgt
     4081 tacgtgatca aatgtttgga taaccttttt aggggctgtt tggtgtttaa tgtcttgaag
     4141 cccgccagtt gcataaccag ctcctaaaag aatggctcct aaaacaatac acacgacact
     4201 ggtcataaaa catttgcgtg agatattttt catgcttgag ctcctttctt gtgactaatc
     4261 catttaataa aggcaacgaa ggcacgtcct gaaaaacgca ggagtgcagt ggcaataatc
     4321 caaatgagaa gaccaccacc aaaacacaac aaggcgctgc cgattcccat agcttgtgca
     4381 ggaatagatg agccaatcaa ggtcaagctt tcaaacaggg tcactcctgc gacaagaata
     4441 cctgcaagcc caaaaatgta ggcggcaaag atagctgtga gcccgagcat taggcaggca
     4501 ataataaaga gaatcaacgc cagcaatacg ggtaaagcaa tcggagcagc aaagagggac
     4561 aaaatggtta atccaataat tgttgcccga tttttgggag ttttctcggg agttgccaag
     4621 tgttttccta gaacatttga aatgatttca ctggcagctt ccttaggatt tcctaaatcg
     4681 tcgataacct ggctttcttt gtcaggacca gcttcatcaa aatattcaat ataatattcc
     4741 aacgcttcat ggtagtcttc tctaggtagt ttgcgcaagt atttatctag ttctgctaga
     4801 tactcagtcc ttgtcatgtc ttaagctccc ttcaataatc ccgtctaagg caaatttata
     4861 gctctgccat tcttttttta gaaaaatcag ctgtgctctc cccgaagaag tgacagcata
     4921 atatttacgc tttcgtccct gatgttcttg actataagtt gtcaaaaaac ctgccttctc
     4981 caatttttta agaataggat agagggtgga ttctttgata ttagccacta gtttaatggt
     5041 ttgactaata tcgtaaccgt aagaatcgtt tttttcgaca atggctaaaa tcagaaattc
     5101 aatcaaggta gccgatactg gaaaataca
//
LOCUS       DATWVB010000067         5110 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.067, whole genome shotgun sequence.
ACCESSION   DATWVB010000067 DATWVB010000000
VERSION     DATWVB010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5110
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.067"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            579..3605
                     /locus_tag="VCX65_001651"
     CDS             579..3605
                     /locus_tag="VCX65_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEP5054100.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSGPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQITSGSQLEQSKESLSLNKTVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPYGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTIGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STMVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKATKNGQLLERSINRAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSNPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            3625..4026
                     /locus_tag="VCX65_001652"
     CDS             3625..4026
                     /locus_tag="VCX65_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEP5054101.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINSESN"
     gene            complement(4216..5091)
                     /locus_tag="VCX65_001653"
     CDS             complement(4216..5091)
                     /locus_tag="VCX65_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEP5054102.1"
                     /translation="MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLKESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSGIEVN"
BASE COUNT         1809 a          793 c          969 g         1539 t
ORIGIN      
        1 tatattcttt acattctgat gaaaatacaa attatcctaa catgatgtat tgaaaggaga
       61 aatagtttat gttagtatac tgattaagtg aagctgtaat gaggcttata cgatcaaaaa
      121 agttagagta actttataaa acagtggtgt tgaagcaagt ttagcttctt ctcagaaata
      181 gattatctat aaaaaatccc aaaagtagtt tgtttccagt taatgaactt cttttgggaa
      241 ggcttttttg ctgatcgcca cttcacttgt atatcgggaa cattcacgct aagatgtata
      301 agttgaatcg tttgtctatg gcttgatgaa aattaatcaa aagataatgt tcaactctat
      361 aattagtaca agcaaaatga gataacttat tcattagtaa gcataagata taacaagaga
      421 aattacctta aaacaggaag tactagagta tttaaaataa gtgatagact tggatattat
      481 taggtcgact agtgttcttt tcaataattt aatatcgtta ttattagtat cagccaatca
      541 aatgtggata agttggcttt tagaaaggtt ttaccacaat gaagaaacat cttaaaacag
      601 ttgccttgac cctcactaca gtatcggtag tcacccacaa tcaggaagtt tttagtttag
      661 tcaaagagcc gattcttaaa caaactcaag cttcttcatc gatttctggc gctgactacg
      721 cagaaagtag cggtaaaagc aagttaaaga ttaatgaaac ttctggccct gttgatgata
      781 cagtcactga cttattttcg gataaacgta ctactcctga aaaaataaaa gataatcttg
      841 ctaaaggtcc gagagaacaa gagttaaagg cagtaacaga gaatacagaa tcagaaaagc
      901 agatcacttc tggatctcaa ctagaacaat caaaagagtc tctttcttta aataaaacag
      961 tgccatcaac gtctaattgg gagatttgtg attttattac taaggggaat acccttgttg
     1021 gtctttcaaa atcaggtgtt gaaaagttat ctcaaactga tcatctcgta ttgcctagtc
     1081 aagcagcaga tggaactcaa ttgatacaag tagctagttt tgcttttact ccagataaaa
     1141 agacggcaat tgcagaatat accagtaggg ctggagaaaa tggggaaata agccaactag
     1201 atgtggatgg aaaagaaatt attaacgaag gtgaggtttt taattcttat ctactaaaga
     1261 aggtaacaat cccaactggt tataaacata ttggtcaaga tgcttttgtg gacaataaga
     1321 atattgctga ggttaatctt cctgaaagcc tcgagactat ttctgactat gcttttgctc
     1381 acctagcttt gaaacagatc gatttgccag ataatttaaa agcgattgga gaattagctt
     1441 tttttgataa tcaaattaca ggtaaacttt ctttgccacg tcagttaatg cgattagcag
     1501 aacgtgcttt taaatcaaac catatcaaaa caattgagtt tagaggaaat agtctaaaag
     1561 tgatagggga agctagtttt caagataatg atctgagtca actaatgcta cctgacggtc
     1621 ttgaaaaaat agaatcagaa gcttttacag gaaatccagg agatgatcac tacaataacc
     1681 gtgttgtttt gtggacaaaa tctggaaaaa atccttatgg tcttgctact gaaaatacct
     1741 atgttaatcc tgataagtca ctatggcagg aaagtcctga gattgattat actaaatggt
     1801 tagaggaaga ttttacctat caaaaaaata gtgttacagg tttttcaaat aaaggcttac
     1861 aaaaagtaaa acgtaataaa aacttagaaa ttccaaaaca gcacaatggt gttactatta
     1921 ctgaaattgg tgataatgct tttcgcaatg ttgattttca aaataaaact ttacgtaaat
     1981 atgatttgga agaagtaaag cttccctcaa ctattcggaa aataggtgct tttgcttttc
     2041 aatctaataa cttgaaatct tttgaagcaa gtgacgattt agaagagatt aaagagggag
     2101 cctttatgaa taatcgtatt gaaaccttgg aattaaaaga taaattagtt actattggtg
     2161 atgcggcttt ccatattaat catatttatg ccattgttct tccagaatct gtacaagaaa
     2221 tagggcgttc agcatttcgg caaaatggtg caaataatct tatttttatg ggaagtaagg
     2281 ttaagaccat aggtgagatg gcatttttat caaatagact tgaacatctg gatctttctg
     2341 agcaaaaaca gttaacagag attcctgttc aagccttttc agacaatgcc ttgaaagaag
     2401 tattattacc agcatcactg aaaacgattc gagaagaagc cttcaaaaag aatcatttaa
     2461 aacaactgga agtggcatct gccttgtccc atattgcttt taatgcttta gatgataatg
     2521 atggtgatga acaatttgac aataaagtgg ttgttaaaac gcatcataat tcctacgcac
     2581 tagcagatgg tgagcatttt atcgttgatc cagataagtt atcttctaca atggtagacc
     2641 ttgaaaagat tttaaaacta atcgaaggtt tagattattc tacattacgt cagactactc
     2701 aaactcagtt tagagacatg actactgcag gtaaagcgtt gttgtcaaaa tctaacctcc
     2761 gacaaggaga aaaacaaaaa ttccttcaag aagcacaatt tttccttggc cgcgttgatt
     2821 tggataaagc catagctaaa gctgagaagg ctttagtgac caagaaggca acaaagaatg
     2881 gtcagttgct tgaaagaagt attaacagag cggtattagc ttataataat agcgctatta
     2941 aaaaagctaa tgttaagcgc ttggaaaaag agttagactt gctaacagga ttagttgagg
     3001 gaaaaggacc attagcgcaa gctacaatgg tacaaggagt ttatttatta aagacgcctt
     3061 tgccattgcc agagtattat atcggattga acgtttattt tgacaagtct ggaaaattga
     3121 tttatgcact tgatatgagt gatactattg gcgagggaca aaaagacgct tatggtaatc
     3181 ctatattaaa tgttgacgag gataatgaag gttatcatgc cttggcagtt gccactttag
     3241 ctgattatga ggggctcgac atcaaaacaa ttttaaatag taagcttagt caattaacat
     3301 ctattcgtca ggtaccgact gcagcctatc atagagccgg tattttccaa gctatccaaa
     3361 atgcagcggc agaagcagag cagttattgc ctaaaccagg tacgcactct gagaaatcaa
     3421 gctcaagtga atctgctaac tctaaagata gaggattgca atcaaaccca aaaacgaata
     3481 gaggacgaca ctctgcaata ttgcctagga cagggtcaaa aggcagcttt gtctatggaa
     3541 tcttaggtta cactagcgtt gctttactgt cactaataac tgctataaaa aagaaaaaat
     3601 attaaattga tttaaggaga agaaatgata acacaagaaa tgaaagatct tattaataac
     3661 caattagcaa tggttgcgac ggttgatgcc aaaggtcaac ccaatattgg tccaaaacgt
     3721 tctatgcgtc tctgggatga taaaacattt atttataatg aaaatacaga tggtcaaact
     3781 cgtattaaca ttgaagataa tgggaaaatt gaaattgcct ttgttgatcg tgagcgcctt
     3841 ttaggttaca ggtttgtagg aactgctgaa attcaaacag aaggtgctta ttacgaagca
     3901 gcgaaaaaat gggcacaagg acgcatgggg gtaccaaaag cagttggtat tattcatgtc
     3961 gagcgtattt ttaatttaca atctggtgct aatgcaggta aagaaataaa cagtgaaagt
     4021 aactaaaatt aactaaaatt aactgtaaca gtatttagga cccttatttt aaatgctaaa
     4081 aaacaagcat actctttttt acagcatagt gactatgttg taaaaagggg tatgcttatt
     4141 aggtgctctt aatatttcta gataactgca cctaataagt tttcaataga cttatagcac
     4201 attagttgac ttcaattagt tgacttcaat accagaaaga gaagaacagt gatgttggtg
     4261 ttcgtttaaa gaagtatcga tttccacagt gactgagttt atattgtacc tttgacaaat
     4321 cagtctaata gattttttgc aatgtttttc agtggtagat tctttcaagc agcaatgtat
     4381 agttgctcta tggtcaatac catccatcga ccaaacatta agctgattaa cagacactat
     4441 atgaggaagt tggctgagtt catggtgcaa agcgcaatag tctatcgaat caggaacacc
     4501 atctaaaaaa atgttagcgg ttgctactaa ctttggaaga gctttagata atataaaaga
     4561 agcaatggca attgataata aaggatcaag aatgtaccaa ggtttccatt ttaagatcag
     4621 tgacagtatg ataatggcta accatccaag gatatcttct aaaaagtgaa ggcttaatat
     4681 ttcttcattt tttgtctggt tagagtgaat gatgaagcta gcaaatccat tgattataat
     4741 tgcaaaaata gctaaaacga acataccgtc ataattaaca atagtaggat gccataattt
     4801 tggtatcgtt tcaatcatta ctaataatga cccgctaata agtattagat ttgtcgttag
     4861 cgctcctaaa aggctaaatc gcttatagcc tagtgaaaaa tttggactct cttttttaac
     4921 agcctttctt tctaagatag ctgagatacc aatagcaatg gcatctccaa aatcgtggac
     4981 agcatctgct aaaatagcac ccgaaaagaa taatgttcca aaaataaatt caatgaggga
     5041 aaaactaaga tttaatataa aaataatggt gactttttta cttgctggca taattttctc
     5101 cttttgttat
//
LOCUS       DATWVB010000068         5091 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.068, whole genome shotgun sequence.
ACCESSION   DATWVB010000068 DATWVB010000000
VERSION     DATWVB010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5091
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.068"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            38..256
                     /locus_tag="VCX65_001654"
     CDS             38..256
                     /locus_tag="VCX65_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HEP5054103.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            276..2435
                     /gene="nrdE"
                     /locus_tag="VCX65_001655"
     CDS             276..2435
                     /gene="nrdE"
                     /locus_tag="VCX65_001655"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEP5054104.1"
                     /translation="MSLKDIGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYRPEFITELDSIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEYYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQASDWEALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            2768..3727
                     /gene="nrdF"
                     /locus_tag="VCX65_001656"
     CDS             2768..3727
                     /gene="nrdF"
                     /locus_tag="VCX65_001656"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEP5054105.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINNIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            3702..5015
                     /locus_tag="VCX65_001657"
     CDS             3702..5015
                     /locus_tag="VCX65_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEP5054106.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
                     SLWSQRCNLSKADQKLLLACASSAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIWSVLAGLILSLFAHAYKHLLEHLPK
                     ADAKSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
BASE COUNT         1513 a         1029 c          906 g         1643 t
ORIGIN      
        1 taagatggaa ccattactaa ttttagaagg acaagacatg attacagtat attccaaaaa
       61 taattgcatg cagtgcaaaa tgactaagaa atttttagaa caacacggag ccaacttcca
      121 ggaaattaat atcgatgaac atcctgaaaa agtggattat gtgaaaagtc ttggcttcac
      181 atctgctcct gttatcgaag cagataacct cgtattttct ggcttccaac ctgcaaagtt
      241 aaaagaattg atttaataag acaaggaaaa ataatatgag tctcaaagat attggcgata
      301 tttcatattt tcgcctaaat aatgaaatta accgtcctgt taatggtaaa attccacttc
      361 ataaagacaa agaagcttta aaagcttttt tcgctgaaaa tgtgctgcca aacaccatgt
      421 cttttacttc cattacggaa aaaattgagt atttaatctc aaatgattac attgaatcag
      481 cttttattca gaaataccgt cctgaattta ttactgaatt agatagcata atcaaatcag
      541 aaaattttcg ctttaaatca tttatggcag cctacaagtt ctaccagcaa tacgccttaa
      601 aaacaaatga tggagagtat tatttagaaa accttgaaga ccgtgtcttg tttaatgctt
      661 tgtattttgc agatggtcaa gaagacttag caaaagattt agccgttgaa atgattaacc
      721 aacgttacca accggctact ccttcctttt taaatgctgg tcgaagccgt cgtggtgaat
      781 tggtctcttg tttcttgatt caagtaactg atgacatgaa ttctatcgga cgttccatta
      841 actctgcctt gcaattatcc cgtattggtg gaggtgttgg gattaccttg tctaacctcc
      901 gtgaagctgg cgcaccaatc aaaggctatg ctggtgcagc ctcaggagtt gttcctgtta
      961 tgaaattatt tgaagatagt ttttcttatt caaatcaact tgggcaacgt caaggagctg
     1021 gtgttgttta cctaaatgtt tttcatcctg atatcattgc tttcttatct actaaaaaag
     1081 aaaatgccga tgaaaaggtg cgtgttaaaa ccttgtcact agggattacc gttcctgata
     1141 aattctacga attagctcgt aaaaacgagg acatgtatct ctttagtcct tacaatgttg
     1201 aaaaagaata tggcattccc tttaactatc tcgacattac caatatgtac gatgagttag
     1261 tggcgaaccc taaaattact aagactaaaa ttaaagctcg tgatcttgaa acagagattt
     1321 caaaattaca acaagaatct ggttaccctt atatcatcaa tattgataca gctaataaag
     1381 ctaatcctat cgatggaaaa atcatcatga gcaacttgtg ttctgaaatt ttacaagttc
     1441 aaacacctag ccttatcaat gatgcgcaag agtttgtaga aatgggaact gatatttcat
     1501 gtaacttagg ttccactaat atcctgaaca tgatgacctc accagacttt ggccgttcta
     1561 ttaagaccat gacacgtgcc ctaacttttg ttactgattc atcaagcatt gaagctgttc
     1621 caaccattaa acatggcaat agccaagctc atacttttgg ccttggagct atgggactac
     1681 attcttacct tgctcaacat catattgaat atggcagtcc agaatccatc gagtttactg
     1741 atatttactt tatgctcctg aattattgga ccttggtcga atccaataac atcgctcgtg
     1801 agcgccaaac tacctttgtt ggctttgaga actctaagta cgctaatggt agttactttg
     1861 ataaatacgt tacaggacac tttgttccaa aatctgattt ggtcaaaagt ctctttaaag
     1921 atcactttat tccgcaagct tcagattggg aggctcttcg cgacgccgtt caaaaagatg
     1981 gtctttatca tcaaaaccgt ctagcagttg ctccaaatgg ctctatttct tatatcaatg
     2041 actgctctgc ttctattcac ccaatcacac aaagaattga agaacgtcaa gaaaagaaaa
     2101 ttggtaaaat ctactatcct gcaaatggtt tgtctacgga taccattcct tactatacat
     2161 ctgcttacga tatggacatg cgcaaagtta ttgatgtcta tgccgctgcg accgaacatg
     2221 tggaccaagg cttgtcatta actctattcc ttcgtagtga gttgcctatg gagctttatg
     2281 agtggaaaac acaaagcaaa caaaccactc gtgatttatc catcttacga aactacgctt
     2341 tcaataaagg cattaaatct atctactata tccgtacctt tacggatgat ggggaagaag
     2401 tgggcgcaaa ccaatgtgaa tcttgtgtca tttaattggt taagaagtaa tgatgctaaa
     2461 gcatctatta cttctacggc agtcgcttta ggcgatctgc ctaaaccact cactaactac
     2521 gtaaggaaag tattatcgac tttccttact ccgtgtcgta attcctcgat atgccctaat
     2581 gatgctaaag catctattac ttcttggaca atcgctttag gcgttccgcc taaaccactc
     2641 actgactcat tcgttaccct tttgaatcta tttaaactta ttattaccgg tagaactttg
     2701 gtcggttcta ctggtttatc tcgatatcct taacgcactt tactactctt taggagatca
     2761 tttttctatg actacatatt atgaagcaat taactggaat gaaatcgaag acgtcattga
     2821 caagtcaact tgggaaaagt tgaccgaaca attttggctt gatacccgta tccctttatc
     2881 aaatgactta gacgattggc gcaaactttc tcttcaagaa aaagatcttg ttggcaaggt
     2941 ttttggagga ttaaccctac ttgataccat gcaatcagaa actggtgtcg aagctattcg
     3001 tgctgatgtt cgcactcctc acgaagaagc tgtcttaaac aatattcaat ttatggaatc
     3061 agttcatgct aaatcatact cgtctatctt ttcaacctta aacaccaaaa aagaaattga
     3121 agagatcttt gagtggacta ataataatga gttccttcaa gaaaaagcac gtattatcaa
     3181 taacatttac gctaatggag atgccttaca aaagaaagtt gcctcaacat atctcgaaac
     3241 tttccttttt tattctggct ttttcacccc tctttactat ttgggaaata ataagctagc
     3301 aaatgttgct gaaatcatta aactaattat tcgtgatgaa tctgtacatg gtacttatat
     3361 cggttacaaa ttccagcttg gttttaacga actaccagaa gatgagcaag agaattttcg
     3421 tgattggatg tatgacctcc tttatcagct gtatgaaaat gaagaaaaat acaccaaaac
     3481 gctttatgat ggcgtagggt ggactgagga agttatgacc tttttacgct acaatgctaa
     3541 caaagctctt atgaatttag gacaagatcc tttattccca gatactgcaa acgatgttaa
     3601 cccaattgtt atgaatggta tttcaacagg aacatcaaac catgactttt tctcacaggt
     3661 agggaatggc tatcttcttg gttctgtaga agctatgtct gatgacgatt ataattatgg
     3721 actctaatag tgctcacgag actgataatc tatcagtctc ttttcttaac ttttgttata
     3781 atagtcttat gaaacgacac tttttactct tgacctttta cctcttttta acaggtttaa
     3841 cagctggcct tgttgctttt atcttaacaa aagccattca cctgattcag tccctcagtt
     3901 ttggattcag tcaaggttct tttagcacta tgattgctag cgttccacca caaagacgag
     3961 ctctttcact tctctttgct ggacttcttg caggtcttgg gtggcaccta ttggctaaaa
     4021 aaggaaagga cattcaatct attcagcaaa tcattcaaga tgacatctca tttagtccct
     4081 ggacacagtt ttggcatggt tggctccaat taacgaccgt atctatggga gctcctgtcg
     4141 gccgagaagg agcttcacgg gaagtcgctg ttaccttgac gtctctttgg agccaaagat
     4201 gcaacttgtc aaaagccgat caaaaacttt tattagcttg cgcttctagc gctgcccttg
     4261 gtgctgtcta caatgctccc ttagccacta ttttatttat cttggaagct attcttaacc
     4321 gttggtccct taaaaatata tacgctgcct gcctaacgag ctatgtggct gtggaaacag
     4381 ttgctttatt acaaggccga catgagattc aatacctaat gcctcagcaa cattggacgc
     4441 taggaaccct tatttggtcc gtcctggctg gtcttatcct ttccctcttt gctcacgctt
     4501 acaaacatct tttggaacac cttcctaagg ctgatgccaa aagtcagtgg tttattccga
     4561 aagttctcat cgcttttagc cttatcgcag gactcagcat tttcttccca gagattttag
     4621 gaaatggcaa agctggatta ctcttttttc tccatgaaga accacatctg agctatatta
     4681 gctggctact tgttgccaaa gctgtcgcta tctctttagt ttttgcttct ggagcaaaag
     4741 ggggtaaaat tgctccttct atgatgcttg gaggtgctag tggcttacta ctagctatcc
     4801 ttagtcagta ccttattccc ttgtctctat caaatacgtt agccattatg gttggtgcaa
     4861 caatcttttt aggtgtgatc aataagatac ccttggcggc accagttttt ctggttgaaa
     4921 ttacaggcca atcgttacta atgattatcc ctttagcatt agctaacctc attttttatt
     4981 ttagctatca gttttatcgt ttcatcctta aatgattagt taattacttt tttaataaaa
     5041 agcttcggat gaattggact tggtatacta aagtagacac aaaattaagt g
//
LOCUS       DATWVB010000069         4898 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.069, whole genome shotgun sequence.
ACCESSION   DATWVB010000069 DATWVB010000000
VERSION     DATWVB010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4898
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.069"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     misc_feature    12..147
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            176..676
                     /locus_tag="VCX65_001658"
     CDS             176..676
                     /locus_tag="VCX65_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEP5054107.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            741..1106
                     /gene="rplL"
                     /locus_tag="VCX65_001659"
     CDS             741..1106
                     /gene="rplL"
                     /locus_tag="VCX65_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEP5054108.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            1365..1964
                     /locus_tag="VCX65_001660"
                     /pseudo
     CDS             1365..1964
                     /locus_tag="VCX65_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein"
     gene            2139..2464
                     /locus_tag="VCX65_001661"
                     /pseudo
     CDS             2139..2464
                     /locus_tag="VCX65_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            2455..2729
                     /locus_tag="VCX65_001662"
                     /pseudo
     CDS             2455..2729
                     /locus_tag="VCX65_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            2775..2987
                     /locus_tag="VCX65_001663"
     CDS             2775..2987
                     /locus_tag="VCX65_001663"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054109.1"
                     /translation="MMTDRVMKKPIRGRQLSKRDLYDEEFFRTHFAKIEIESRLEFLL
                     NRANSLEELLLKAKEVNLTIDLKQKM"
     gene            3252..3949
                     /locus_tag="VCX65_001664"
                     /pseudo
     CDS             3252..3949
                     /locus_tag="VCX65_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
     gene            4100..4786
                     /locus_tag="VCX65_001665"
     CDS             4100..4786
                     /locus_tag="VCX65_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP5054110.1"
                     /translation="MYKILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFK
                     GYDLILLDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKP
                     FSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYR
                     EYEILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEYIYQIRMKFSSFGINPIKT
                     IRGIGYKWDV"
BASE COUNT         1688 a          732 c         1026 g         1452 t
ORIGIN      
        1 taatgatata ggttttgata aaaaactgac ctaagacagc aggggagcat gctcataata
       61 ttcctgccga ggcacaaaac gtgattaaag aaaataacgt atttgtactt tcgtgtctag
      121 gtttaggtgc gatttttttg tacctagccc aaaaataaaa acggaggtaa aactaatgag
      181 tgaagcaatt attgctaaaa aagctgaaca agtcgaactt attgctgaga aaatgaaagc
      241 agcagcaagt atcgttgttg ttgattcacg tggtcttaca gttgatcaag atactgttct
      301 tcgtcgttca cttcgtgaaa gtggcgttga gttcaaagtt atcaaaaact caattttgac
      361 tcgtgcagct gaaaaagcag gtcttgatga gttgaaagat gtattcgtag gaccatctgc
      421 agtagcattt tctaacgaag atgttatcgc accagctaaa gttatcaacg actttactaa
      481 aactgctgac gcacttgaaa tcaaaggtgg tgcaatcgaa ggcgctgttt cttcaaaaga
      541 agaaatccaa gcacttgcaa cattgccaaa ccgcgaagga atgctttcta tgcttctttc
      601 tgtacttcaa gctccagtcc gcaacgttgc atacgctgtc aaagctgttg cagaaaacaa
      661 agaaggcgct gcttaagacg tctcagagta gcttaaggct acgcttaaca ttttaaatta
      721 attatttgga ggaaatcaca atggcattga acattgaaaa cattattgct gaaattaaag
      781 aagcttcaat ccttgagctt aacgatcttg taaaagctat cgaagaagaa tttggtgtaa
      841 ctgcagctgc tcctgtagct gctgcagctg ctggtggtgc tgaagaagct gctaaagatt
      901 cattcgacgt tgaattgaca tctgctggcg acaaaaaagt tggcgttatc aaagctgttc
      961 gtgaaatcac aggtcttggt cttaaagaag ctaaaggtct tgttgatgga gcacctgcta
     1021 acgttaaaga aggcgttgct gctgcagaag ctgaagaaat caaagctaaa cttgaagaag
     1081 ctggagcaac aatcactctt aaataagaag cagatagcaa tttgagagcg aaatcccgat
     1141 ttatcagtct tttagagctt atagcgattt gaagaaactg ataaaatgat ttggtttttt
     1201 gccaaaaatc ctgccaaaaa aatctttggc aggattttta ttttctataa aaattaagct
     1261 gagtagagtg gttattctat ctatatgtgt ctagtaataa tttttttatt ttcaggagga
     1321 aaatcatgca aatgaatgaa cagtcatcac gacaaatggt gattgccatc tatctcattt
     1381 attccaactc aaaatgatag tactccttgg ctgttccaag tcgaaattgt tagtgattaa
     1441 gaaaacctac gagactatgg tttgatcgat gaaggccagc agtctcccag tgaaaaaggg
     1501 cgtttggcta ataagattta tttaggaaag ttggaacatg atttcacccc agtcttaagt
     1561 tcagacgggg ccagtctcaa aaacagacca gccccgtgtt aaattcagcc cctagtgaga
     1621 ctgaaaagag tgaaactgaa ggtagtgaaa ctaaagagag taatttagtc attgaggacg
     1681 aggaggaaag aaaggagtgc actagtgtga aaaagactga gggtcacttt actcgtcaag
     1741 ttgatcatgt caccaaatat gacaaagatt atatttggag tttggttcat tcccaattac
     1801 gtgaaggtgg tttatcacaa gctgctagtg acttagtcat gagctatttt gaagaacgct
     1861 atgcttatgc gctggaacac atacggttcg caagaacagc tgaagctatt gcggaatatg
     1921 tctttaatgg tgtcttatcc gaatggacca agcaactaag gtgacaagaa gcgaagtgag
     1981 taagatgttt tggtggctat tattaggtgt ttggggacta aggacaattt ggttgattat
     2041 tgaagttatc actgcaccag aaatggaaga ttatagttga gtaaggacgt tacataagca
     2101 gtaaggtcct tttattttgt cagaaaggaa tgagagatat gcagttttta gatttgtttg
     2161 caggaattgg aggctttcga ttgggtttaa ttaatcagtg ccatgagtgt attggctttt
     2221 gtgagattga taagtttgcg aggcaatctt acaaagccat ctatgagacc gaaggagaaa
     2281 tagaatttca tgacattaga caagtcacag accaagactt tagacaactt agagggcaag
     2341 tggatatcat ctgcggtggt ttttcccttg tcaagcattt tcactcgcag gcagacgact
     2401 gggatttgag ggcactagga gaactctctt ctttgagatt actcgagcga ccaaacagat
     2461 aaaaatcata cccataatca catccaatca acgccattga ccgtaattca gataaaaaat
     2521 tgatatggaa ttatgccttg gaacgaaacc tccgtatgat tttagaccgt atttcaaaaa
     2581 tgactggagc aaaaattatc gagaagcgtt attcctaccg tgactatcaa aaatataggc
     2641 agtctagtca taaatttgaa ttgaaacaac gtctttattt tttgatgcag cagtcaaagt
     2701 tctttgatga ttttttagaa aaagcagagt aattacatgt tcatattgat tttagtcaga
     2761 agcatagcag attcatgatg acggatcgag taatgaaaaa accaattcga ggccgtcaac
     2821 tcagtaaacg agatttatat gatgaagaat tttttcgtac acattttgcc aagatagaaa
     2881 ttgaaagtcg attagaattt ttgttgaacc gtgccaattc attagaggag ctactattaa
     2941 aagcaaaaga agtgaatcta accattgact taaaacaaaa aatgtaactt ttatcctaga
     3001 agaagatact caaaagataa gtttaggtca taaaaaaata agcgataaga aattatatga
     3061 tgtcaatttt ttcaagatta ctttaaaaat aaggaagtcg gtgtttcaga tcgattagaa
     3121 agtctacaga aacagtacat gcttttcaag aagaacgaga taaagaggag gtatccactg
     3181 aagagagtaa ggaagtcttc aagaaataca aggggcaacg agatgccatc catgagtttg
     3241 aagttgaact tgtggaacat caaattgaga ggttaattgc tgaggacatt tatattaagg
     3301 tgtcttttgg tgtaaagcag agtggtctta ttttcattcc taactatcaa ttggatatta
     3361 ggaaagaaga aaatcataaa aaatataaag tctatattcg tgagaccgca caattcttca
     3421 tttacaacaa ggaggcgtct aaacttaatc gctatatgcg agggcgtgag ctcatttacc
     3481 agttaaccaa tgatagcaag agtattccaa aaagaagacg accaaaacca ttgatacact
     3541 taagaaaaag attgaagaaa taagtctcct cattgagtta gatacggaga ataagcctta
     3601 tcaagatatt aaagatgaca ttgttaaaga tatggctcaa ttagatttga ccattacaga
     3661 gttgcaggac catattgctc atctcaataa ggttgcggag gtcttgctta atatgaacaa
     3721 caacgatata gagaaccgcc gtttggccag atatgactat gccaagatga acttgactgc
     3781 agctataaaa atagaagaag ttgagaaaga gattgaaact tctcaaaatg aacttaatat
     3841 atccatagat gagtatgaat atctagtaag aaggttggaa aagtttggag agatcttgag
     3901 ttatagcaaa attatcgata cttctcgaaa tgaaatacaa tgggagtaat tatgatataa
     3961 tttgggtggt agcaattttt atatcagata ttaaaatcta gttgatgttt cgtaaataac
     4021 tatattaaag aaatgattcc tgccgcttac attgagaata gtttatttgt aagtatttca
     4081 ttatttaaaa ggggtaataa tgtataagat tttagccata gatgatgata aagaaattct
     4141 gaagcttatg aagactgctt tggagattga aaattaccat gttataacct gtcaagagat
     4201 agaattacca atagtttttg atgattttaa aggatatgat ttgatcttat tggatatcat
     4261 gatgcctaat ataagtggaa ctgagttttg ttataaaatt cgggaagaag ttcattctcc
     4321 aattattttt gttagcgctt tagatggcga taatgaaatt gtccaagctt taaatatagg
     4381 gggagacgat tttattgtga aaccatttag cttaaaacaa ttcgtagcta aagttaactc
     4441 tcatttgaag agagaagaga gagcaaagat aaagaatgag gctgaggaga gagtgaagcg
     4501 cagttttcca cctatagaaa tctatctaga ggaacgtatg ttatatattg ataaacagcc
     4561 gttattcctg acttatagag agtacgaaat tttagaatta ctgtcacgtc atccgtataa
     4621 agttttcaca aaagaagaga tatatgaaca agtatatagc gatgaagctt cagcattgtt
     4681 tcattctatt tcagaatata tctatcagat tagaatgaaa ttttcaagtt ttggaattaa
     4741 tccaataaaa actattcgcg ggattggtta taaatgggat gtttaaaaaa tattcaataa
     4801 aaaatcgtgt ttggcgcgcc gtcgttgaaa ttgtctttgg agtttgtatc actgttttaa
     4861 tgattgcgat aatatcgctt tctttttcaa agttaaat
//
LOCUS       DATWVB010000070         4771 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.070, whole genome shotgun sequence.
ACCESSION   DATWVB010000070 DATWVB010000000
VERSION     DATWVB010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4771
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.070"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            60..1256
                     /locus_tag="VCX65_001666"
     CDS             60..1256
                     /locus_tag="VCX65_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP5054111.1"
                     /translation="MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLVAATANLALQLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPAAPSAGPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYR
                     TGSTPMVGAIAVWNDGGYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGV
                     TFIYPH"
     gene            1509..2471
                     /locus_tag="VCX65_001667"
     CDS             1509..2471
                     /locus_tag="VCX65_001667"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEP5054112.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMDLQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEMGN"
     gene            2657..3412
                     /gene="recO"
                     /locus_tag="VCX65_001668"
     CDS             2657..3412
                     /gene="recO"
                     /locus_tag="VCX65_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEP5054113.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            3515..4522
                     /gene="plsX"
                     /locus_tag="VCX65_001669"
     CDS             3515..4522
                     /gene="plsX"
                     /locus_tag="VCX65_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEP5054114.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMRKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            4515..4757
                     /locus_tag="VCX65_001670"
     CDS             4515..4757
                     /locus_tag="VCX65_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEP5054115.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHLAIPDEDVEDMVFMGDVLDYLVQRLT"
BASE COUNT         1547 a          741 c          987 g         1496 t
ORIGIN      
        1 atactttttt ttttggtaaa atataagatg tcttatcgaa aaggagtagt ttttttatta
       61 tgaaaaaaag aattttatca gcagttcttg taagtggtgt taccctcgga gcagctacaa
      121 ctgtaggagc ggaggattta agtactaaga ttgctaagca agattctatt atctcaaatc
      181 tgactacaga gcaaaaagct gcacagaatc aagtttcagc gttacaggct caagtaagtt
      241 cactacaatc tgaacaagat aaactgaccg caagaaatac agaacttgag gcgctttcaa
      301 agcgatttga gcaagaaatt aaggctctaa caagtcaaat tgttgctcgt aatgaaaaat
      361 taaaaaatca agctcgtagt gcttataaaa acaatgaaac ttctggttat attaatgcac
      421 ttttgaattc taaatcaatt tctgatgttg taaaccgttt agtagcaatt aatagagctg
      481 tctctgctaa cgctaaattg ttagaacaac aaaaagctga taaagtttcc cttgaagaaa
      541 agcaagctgc taaccaaaca gctattaata ccattgccgc taatatggca atggctgaag
      601 aaaaccaaaa tacattacgt actcaacaag ctaatttggt agctgcaact gcaaatttag
      661 ctctccaatt agcatctgct actgaagata aagctaattt ggtagctcaa aaagaagctg
      721 cagaaaaagc tgctgctgaa gccttagcac aagaacaggc tgctaaagtt aaggcacaag
      781 aacaggctgc acaacaagca gcatctgttg aagcagcaaa atctgctatt actccagcac
      841 cacaagctac tccggcagcg caaagtagta atgctattga accagctgca ctcacggctc
      901 cggcagctcc ttctgcagga ccacaaacat catatgattc ttctaatact tatccagttg
      961 gacaatgcac atggggagct aaatctttag ctccttgggc aggaaataat tggggaaatg
     1021 gtggtcaatg ggcttatagt gctcaagcag ctggttatcg tactggttca acgccgatgg
     1081 taggtgcgat tgccgtttgg aacgatggtg gttatggaca tgtcgccgtt gtagttgagg
     1141 ttcaaagtgc ctcaagtatt cgtgtgatgg agtctaacta cagtggtaga cagtacattg
     1201 ctgaccaccg tggctggttt aatccaacag gtgttacatt tatttatcca cactaacata
     1261 ttatttaggt tagaacagtt gttctaacct ttttgattac tcctattgtg gaatagttct
     1321 gagagtattg acgatatagt taatttataa gagagttgtt tggccaatcg cttatgtata
     1381 atataagaga agtatataaa gtcgataaaa ggtatattta atacattctt taacggtttt
     1441 tcaatttcat ttgataattc acttgaaaag cgttaaaatg gtataggatt aaaactttgg
     1501 aggaaaaaat gtcttattct gatttaaaat tgtttgcttt atcgtcaaac aaggaattag
     1561 cagaaaaagt tgcgtctgca atggatcttc aacttggaaa gtctacggtt cgccagtttt
     1621 cagatggtga aatccaagta aatattgaag aatcaattcg tggtcatcat gtctttattt
     1681 tgcaatcaac tagctcacct gtcaatgaca atttaatgga aattttgatt atggtcgatg
     1741 ctttaaagcg tgctagtgct gaaaaaattt cagttgtgat gccttactac ggctatgcac
     1801 gccaagaccg taaagcgcgt tctcgtgaac ctattacttc gaaattagtt gctaatatgt
     1861 tagaagttgc tggtgtagat cgcttattaa cggttgattt acatgctgct caaattcaag
     1921 ggttctttga tattccagtt gatcacttga tgggtgcacc tttaattgca gactattttg
     1981 atcgtcatgg tttagtgggt gaagatgttg tcgttgttag tcctgaccat ggtggtgtga
     2041 ctcgtgcgcg taaattagca caattcctcc aaacaccaat tgcaattatc gataagcgtc
     2101 gtagtgtgga taagatgaac accagtgaag tgatgaatat tatcggaaat gtttcgggca
     2161 agaaatgtat cttgattgac gatatgattg ataccgcagg gactatttgc catgcagcag
     2221 atgcgcttgc tgaagcgggg gcaacagctg tgtatgcgtc atgtacgcat cccgttcttt
     2281 ctggaccagc acttgataat attcaacgtt cggctatcga aaaactaatt gttcttgata
     2341 ctatttatct gccaaaagaa cgccttattg ataaaattga acaaatttca attgctgatt
     2401 tggttgcaga agcgattatt cgcattcatg aaaaacgtcc gttgtcacct ttatttgaga
     2461 tgggcaatta aacttaacga agcctgagat aatagatctc aggctttttg acttgaataa
     2521 aatgtaaggg taatgtggta ttaattattg tgggatgaac tatgcaattc taaaggattt
     2581 tgggtataat aagaaagata acaacagttt attgtaaact aagataaaag gtaagagaaa
     2641 aatacgacga ggtaatatgc aactaacaga atcactaggc atcgttcttt ttaataggaa
     2701 ttatcgagaa gatgataaat tagtcaaaat atttactgaa gtagcaggta agcagatgtt
     2761 tttcgtgaaa catattagtc gttccaaaat gtcctcaatc attcaaccac taacgattgc
     2821 tgattttatt ttcaagttaa atgatacagg cttgtcttat gttgttgact atagtaacgt
     2881 taacacttat cggtatatta ataatgatat ttttcgatta gcctatgcta gttatgtctt
     2941 agcattagct gatgctgcga ttgcagataa tgaatcagat tcgcatttgt ttacgttttt
     3001 gaaaaaaaca cttgatttga tggaagaggg cctagattat gaaattttga caaatatttt
     3061 tgaaattcag atattagatc gttttggtat tagtctaaac tttcatgagt gtgccatttg
     3121 tcatcgcact gatttaccgc ttgatttttc ccatcgtttt tcagctgtac tttgttctga
     3181 acattattac aaagacaacc gacgtaatca tttagatcca aatgttatct acttgttgag
     3241 tcgatttcaa aaaatcacat ttgatgattt gagaactatt tcattgaata aagacatcaa
     3301 aaagaagctt cgtcagttca ttgatgagtt gtatcacgac tatgtaggaa tcaaattaaa
     3361 aagtaaaaca ttcattgata atttagttaa gtggggagat attatgaaat gatagggcct
     3421 ctttcgttta tgggaattgg tttcagaata tgctataata aaaatactat taatagattg
     3481 tgtaagaaca caagatataa ttaaaggagt ggaaatgaag agaattgcaa tagatgctat
     3541 gggtggagat aacgctccta aagctattgt tgagggtgtt aatcaagcaa tagaagcatt
     3601 ttcagatatc gaaattcaac tttacggtga tcagacaaag attaactcct atcttattca
     3661 atcagatcgt gttgctatta ttcatacaga tgaaaaaatt atgtcagatg atgaacctgc
     3721 aaaagctgtt cgccgtaaaa agaaggcttc aatggtttta gcagctaagg cagtgaaaga
     3781 aggaaaagca gatgccatta tttcagcagg taatacaggt gctcttttag ctgtaggttt
     3841 gtttgttgtg gggcgtatca agggagttga tcgtccagga ttattatcaa ctattcccac
     3901 agtaaccgga ttaggatttg atatgttgga tcttggagct aatgctgaaa atacggcaaa
     3961 acatttacat caatatgcta ttttaggctc tttctatgct aagaatgtac gtgggattgc
     4021 taatccacgt gttggtctat taaacaatgg tacagaagaa acaaaaggag atccccttcg
     4081 taaggccact tatgaacttt taacagcaga taatacaata tcttttgttg gtaatgtcga
     4141 ggcgcgagaa cttatgtcag gtgttgcaga tgttattgta tcagatggtt tcacgggaaa
     4201 cgcagtgttg aaatcaatag aaggaacagc tattagcatt atggggcaac tgaaacagat
     4261 aattaatagc ggcggtatta agactaaaat tggagctagt ctacttaaaa gtagtcttta
     4321 cgagatgagg aagactcttg actactctag tgctggaggt gcagttttat ttggtttaaa
     4381 ggcacctgtt gtaaagtctc atggttctag tgatgtaaaa gctatttttt caacgataaa
     4441 acaagtacgt acgatgctag acactaacgt ggtcggacaa ttagtagaag aatttgctaa
     4501 ggagactcaa gtaaatgact agacaggaga tttttgaaag actgattaac ttaattcaga
     4561 agcaaagaag ctatttgagt gtagctatta cagaacaaac acatttaaaa aatgatttag
     4621 cggttgactc tattgaacta gttgaattta ttattaatgt tgaagatgaa tttcatcttg
     4681 ctattcctga tgaagatgtt gaggatatgg tatttatggg agacgtttta gattatttag
     4741 ttcagcgttt gacttagtta gaataataaa a
//
LOCUS       DATWVB010000071         4693 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.071, whole genome shotgun sequence.
ACCESSION   DATWVB010000071 DATWVB010000000
VERSION     DATWVB010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4693
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.071"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..329
                     /gene="tilS"
                     /locus_tag="VCX65_001671"
     CDS             <1..329
                     /gene="tilS"
                     /locus_tag="VCX65_001671"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEP5054116.1"
                     /translation="CYRDYCFSFMPKSNEDQGQVSIPLFSLSSIKLRSRQSGDYISFG
                     HFSKKIRRLFIDEKFTIAERQNAIIGEQDEQIIFVLIGNKTYLRKACKHDIMLAKLYI
                     DKLEKG"
     gene            334..876
                     /gene="hpt"
                     /locus_tag="VCX65_001672"
     CDS             334..876
                     /gene="hpt"
                     /locus_tag="VCX65_001672"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEP5054117.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            898..2877
                     /gene="ftsH"
                     /locus_tag="VCX65_001673"
     CDS             898..2877
                     /gene="ftsH"
                     /locus_tag="VCX65_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEP5054118.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     SYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
     gene            3204..4595
                     /locus_tag="VCX65_001674"
     CDS             3204..4595
                     /locus_tag="VCX65_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEP5054119.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     YLAYGYTHSIENK"
BASE COUNT         1566 a          674 c          907 g         1546 t
ORIGIN      
        1 tatgctacag agattattgt ttttcattta tgccaaaaag taacgaagat caaggacagg
       61 taagtatacc tttatttagt ttatcgtcta ttaaattaag aagtcgccaa tctggagatt
      121 atatttcttt tggtcacttt tcaaaaaaaa taagacgttt atttatagat gaaaaattca
      181 caatagctga acgccaaaat gctattattg gagagcaaga tgagcagatt atatttgtat
      241 tgataggtaa taaaacttat ttgagaaaag cttgtaaaca tgatataatg ttggctaaac
      301 tgtatattga taaattagaa aaagggtgac agcatgctcg agcaagatat tcaaaaaatt
      361 ctttactctg aaaatgatat tattcggaaa actaaaaaat taggagaaca attaacaaaa
      421 gattatcaag aaaaaaatcc gcttatgatt ggtgtattaa aaggatcagt tccttttatg
      481 gcagaactaa tgaaacacat cgatactcat gttgaaattg attttatggt agtatcaagt
      541 tatcatggcg gtacatctag cagtggtgaa gttaaaattt taaaagatgt agataccaat
      601 attgaaggaa gagatatcat aattgttgaa gatattattg acaccggtcg caccttaaaa
      661 tatttacgag atatgtttaa gtaccgtaaa gctaatacta tcaaaattgc aacactgttt
      721 gataaacctg aaggtcgtgt tgttaaaatt gaagcagatt atgtttgtta caatattcca
      781 aatgaattta tcgtaggctt tggtttagat tacgcagaaa attatcgcaa tcttccttac
      841 gtaggtgtat taaaagaaga agtctattca aaatagaaaa aggtcaatgt ttactgtatg
      901 aaaaataata aaaataatgg ttttgttaaa aattctttta tatatatatt gatgattatt
      961 gttgtcatca caggatttca attttatctt aagggaacca gcacacaaag ccaacagatt
     1021 agttattcca aattaattaa acatcttaag gctggagata taaaatcttt aagttatcag
     1081 cctagcggta gtattattga agttaaaggg aaatatgaga aacctcaaaa agtgacagtt
     1141 aattcaggac tatcattttt aggtggaaga gcttcaacac aggtaacaga gttctcatct
     1201 ttagtattac ctagtgatac catcttgaaa gaaatgacag cagcagctga taaaaatgga
     1261 acagagctta cagttaagca ggaaagttca agtggtactt ggattacctt cttaatgagc
     1321 tttttaccta ttgttatttt tgctgctttc atgatgatga tgatgaatca aggtggtgga
     1381 ggagctcgtg gtgctatgag tttcggcaaa aataaggcaa aatctcaatc aaaaggcgat
     1441 gttaaagtga gatttacaga cgttgctggt gccgaagaag aaaaacaaga attagtagaa
     1501 gttgttgatt ttttgaaaaa tcctaaaaaa tataaatcac taggagcacg gatcccagcg
     1561 ggagttcttc tagaggggcc tccaggtact ggtaaaacat tactagctaa agctgtagca
     1621 ggtgaagctg gagtgccatt tttcagtatt tcaggttcag attttgtcga aatgtttgtc
     1681 ggtgtaggtg ctagtcgtgt tcgttcttta tttgaggatg ctaaaaaagc tgagcgtgca
     1741 atcatcttta tcgatgaaat tgacgctgta ggtcgtcgtc gtggtgctgg catgggaggc
     1801 ggtaacgatg aacgagaaca gacccttaac caattactca ttgaaatgga tggttttgag
     1861 ggtaatgaga acattatcgt tattgctgca actaaccgta gtgatgtttt agatccagct
     1921 ttactaagac caggtcgttt tgatcgtaag gttttagttg gtcgccctga tgttaaagga
     1981 cgtgaagcca ttttacgtgt tcatgctaaa aataaaccac ttgcaaatga cgttaatttg
     2041 aaagtagtag cccaacagac tccaggtttt gtaggtgctg atcttgaaaa tgttttaaat
     2101 gaagctgcgt tggttgctgc tcgcagaaat aaaattaaaa ttgacgctag tgatattgat
     2161 gaagctgaag atcgtgttat tgctggacca tcaaagaaag atcgcactat ttcgcaaaaa
     2221 gagcgagaaa tggttgctta tcacgaagct ggtcatacta ttgttggttt agttttatct
     2281 aatgcgcgtg tagttcacaa ggtaactatt gtacctcgtg gacgagcagg tggttatatg
     2341 atcgctcttc caaaagaaga tcaaatgctt ctttctaaag aagatctgaa agagcaatta
     2401 gcaggattga tgggtggtcg tgttgctgaa gaaattgttt ttaatgctca aacatcaggt
     2461 gcgtcaaatg actttgagca agctactcag atagcaaggg ccatggttac ggaatatggt
     2521 atgagtgaaa agcttggacc agttcaatat gaaggtaacc atgcgatgat gccaggacag
     2581 atctctcctg aaaaatctta ctctgcccaa acagctcaaa tgattgatga tgaggttcgt
     2641 gaactcttaa atcaagctcg taatcaagca gctgatatca tcaatgagaa tcgagatact
     2701 cataaattga ttgctgaagc tcttctcaaa tatgaaactc tagacgctgc acaaattaaa
     2761 tcaatttatg aaactggtaa aatgccagtt gatttagaaa ctgatgataa tgaagctcat
     2821 gcgttatctt atgacgaaat taaaaataaa atgacagaat ctgaatctgc agaatgatat
     2881 aaaaaagctg aacttataga ttaagttcag cttttttatc aacacaatat ccttgtaaac
     2941 gttatgaatt gtaataggtg cctaattgct agaaatgaga agatgacata cttttttttc
     3001 tttattactt aaagtgagaa agactttggt atttaaaact agaaaattgt taaagccatt
     3061 tgaaaaaatc tattagtgtt ttcttagaat aatagaagaa cagaagatag caaaagtttc
     3121 agtcaaccaa taagatgaaa tttacaatca ttactaacta tgatacactt agtagaaaat
     3181 catttactat agaaggtgat aacatgacta tttttcgtaa aaaaaagaaa tattccaata
     3241 aaacagaaat gcaaaggcac ttcaaagtta ttgatttagt ttttttaggc ctaggttcaa
     3301 tggttggaac aggtatcttt acagttactg gcataggcgc tgctaagtat gcaggtcctg
     3361 ctttaacaat atcgattatc atttccgcga ttgctattgg aattttagcc ttattttatg
     3421 cagaatttgc gtctcgtatg ccttctaacg gtggtgctta tagttatgtt tatgcaacct
     3481 tgggagagtt tccagcatgg cttgttggct ggtatattat tatggaattt ttaacagcta
     3541 tatctagtgt tgctgttggc tggggaagtt atttaaaagg attacttgcc aattataata
     3601 tagtattacc aaacgcttta aatggcacgt tcaatcttaa gaatggaact tacatagata
     3661 ttcttcctgt tttagtgatg tttttcgtga cagggattgt cctaatgaat tcgaaattag
     3721 ccctgagatt caatagtttt ttagttattt taaaattttc agcactggct ttatttatct
     3781 ttgtaggcat tttttttatt gatcacaata attggtctca ttttgctcca tatggtgtag
     3841 gacaaattac tggaggtaaa acaggtatct ttgctggtgc ttctgttatg ttctttgcat
     3901 ttttaggatt tgaatctatt tcaatggcag ttgatgaagt gaaagaacca caaaaaacaa
     3961 ttcctaaagg tatcatttta tctttgatta ttgtaacagc actctatata gttgtcacca
     4021 ctattttaac gggaattgta cactacacta aattaaatgt tccagacgcg gtggcttttg
     4081 ctttaagaaa tattagactt tattgggcag ctgactatgt gtcgatagtt gctattttga
     4141 ctcttattac ggtatgtatt tctatgacct atgcattagc tagaacaatt tacagtatta
     4201 gtagagatgg tttattacct aaatcacttt atactctcac taaaaaaaat aaagtgcctc
     4261 aaaatgctac tcttgtcact ggactacttg ctatgatttg tgcgggaata tttcctttat
     4321 cgagtctagc agagtttgtt aatatttgta ctttagcata tttaattatt ctgtcgggtg
     4381 caattattaa actcagaaga atagaaggag aaccaaaagc aaatgaattt aaaactcctc
     4441 tagtaccatt cctaccaatg ttggcaatta tcatttgtct atcatttatg agccaatata
     4501 aagcttttac ttggattgct tttgctattg ccacaattat tgggacatta atctacttag
     4561 cttatggtta tactcattca atagaaaata aataatgttt tgataataag atttgacatt
     4621 acattataga ctataatgtt tagaagtaaa tgagtagtaa aatcaatacc tacttactta
     4681 tcaaagttgt aat
//
LOCUS       DATWVB010000072         4547 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.072, whole genome shotgun sequence.
ACCESSION   DATWVB010000072 DATWVB010000000
VERSION     DATWVB010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4547
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.072"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            5..78
                     /locus_tag="VCX65_001675"
     tRNA            5..78
                     /locus_tag="VCX65_001675"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Asn,seq:gtt)
     gene            158..231
                     /locus_tag="VCX65_001676"
     tRNA            158..231
                     /locus_tag="VCX65_001676"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:192..194,aa:Arg,seq:acg)
     gene            227..808
                     /locus_tag="VCX65_001677"
     CDS             227..808
                     /locus_tag="VCX65_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEP5054120.1"
                     /translation="MHNEKSNRTLVSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKV
                     KPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYL
                     KDLLCRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQER
                     MQFQALIRGERFKGRRALLRKISPYFKEFAQQL"
     gene            993..1742
                     /gene="truA"
                     /locus_tag="VCX65_001678"
     CDS             993..1742
                     /gene="truA"
                     /locus_tag="VCX65_001678"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEP5054121.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            1732..2496
                     /locus_tag="VCX65_001679"
     CDS             1732..2496
                     /locus_tag="VCX65_001679"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEP5054122.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            2486..2956
                     /locus_tag="VCX65_001680"
     CDS             2486..2956
                     /locus_tag="VCX65_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP5054123.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWLGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRQKKR"
     gene            2970..3530
                     /locus_tag="VCX65_001681"
     CDS             2970..3530
                     /locus_tag="VCX65_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEP5054124.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQFMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(3595..4440)
                     /locus_tag="VCX65_001682"
     CDS             complement(3595..4440)
                     /locus_tag="VCX65_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEP5054125.1"
                     /translation="MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYL
                     FEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
                     GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIV
                     GKPNILGPQNNSNGQFTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYS
                     ITSKS"
BASE COUNT         1444 a          667 c          996 g         1440 t
ORIGIN      
        1 tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat gtcgtaggtt
       61 cgagtcctac tggcggagta gagagaggta ggaagcgtcc tatctttttt tgcattttag
      121 agaagagtgt ggtaagatag aggcaagata tgcgttggca cccttagctc aactggatag
      181 agtacctgac tacgaatcag gcggttagag gttcgactcc tctagggtgc ataatgaaaa
      241 aagcaacagg acattagtgt cctgttgttt ttttgtggtt ctctttatac tagggatagt
      301 taaaaagaaa aggagactca aaatgtcgat agagacaaga gcagcgtttg aaaaagttaa
      361 gcccattatt ttgaaattaa agcgacacta ttatattcaa ttgtgggata gagatgactg
      421 gttacaagaa ggacatatta tcttattaca gttactagaa aggtacccag agttaattga
      481 ggaagaagag cgtttatatc gctattttaa aacaaaattt tcatcttatt tgaaagattt
      541 attatgccgt caagaaagtc aaaagcgtca gttccataag ttagcatatg aagagatagg
      601 ggaggttgca catgccattc catcgagagg gttatggcta gacgactatg tggcttatca
      661 agaggtaata gctagcttag agaaccaatt aaattcgcaa gagcgtatgc agtttcaagc
      721 acttatcagg ggcgaacgtt tcaagggaag acgtgctcta cttaggaaga tcagtcccta
      781 ttttaaggaa tttgcacagc agttgtaagc aagacctata aggaattagg ggtaaatcta
      841 cgaaaaaagg agagagtttg gaggaaatag ctttcttata gcttttaaat cgctagtggc
      901 ttagagtaag cttcaatacg tctttcattt gtttgggtac agtttgatta aaaatagttt
      961 ctcttacgtt taagaaatgt taaaatagta acatggtaag atacaaagca acgatttcct
     1021 atgatgggac tcttttttcg ggttttcaaa gacaaagaca tttacgtacg gttcaagaag
     1081 agattgaaaa aacactctat aaattaaata acggtacaaa aattataatt catggtgcag
     1141 gacgtacgga tgcaggagta catgcttatg gacaggtgat ccattttgat ttgcctcaag
     1201 aacaagaagt tgaaaaatta cgatttgctc ttgatacaca gactcctgaa gatattgatg
     1261 ttgttaatat agaaaaagtg gctgatgatt ttcattgtcg ttatcagaag catttaaaaa
     1321 cttatgaatt tttagttgat aatggtcgac ctaaaaatcc gatgatgcga cactatacca
     1381 ctcattaccc ttatactctt aatattaaac ttatgcaaga agctattaac ggtctggtag
     1441 gtacacacga ttttactggt tttacagcag caggaacttc ggtacaaaat aaggtgcgaa
     1501 cgattaccaa agcaacggta tctcgggatg aaaaaactga ttttttggtg tttacttttt
     1561 caggaaatgg ttttctctat aagcaggtga ggaatatggt gggaactttg ctgaaaattg
     1621 gtaatggtca aatgccagtt gaacaagtta aagtgatttt gagctccaaa aatcgtcagc
     1681 tagctggacc aacgatatct ggaaatgggc tttacttgaa ggagatttgt tatgaaaact
     1741 gattatatcg tgactatatc tgggaacgat attttaagtg gaggtggtct ctatgctgat
     1801 ttagcgactt acataaggta tgacctacag gcctttgtag cggtaacttg tttaactact
     1861 agatctgaag agggctttag tctatttccg gtagctaaag aaattttccg tgatcagttg
     1921 aatagcttta cgaacgctcc aatttctgct attaaaattg gtttgttacc taatgcggaa
     1981 atgtgtgaaa tagttttgga ttttataaag gggcatctgg gaatcccagt ggttttagat
     2041 cctgttctag catgtaaaga aatagatgat gttaaaatag ttcctctaag acaggagatt
     2101 ttacaattat tgccttatgt aactgttgtt actccaaatt tggtagaggc tcagctatta
     2161 tctcaaaaag agattgtttc tttaaaagat atgcaagaag ctgctaaata tttttatcaa
     2221 cttggggcaa aacaggtggt tatcaagggt ggtaatcgat ttagtcagaa aaaggctatt
     2281 gatctttttt atgacggtaa agagattgtt accttggaat gtcctgtact tgagaaaaat
     2341 aatattggcg caggctgtac ttttgcatct agtatcgcta gtcagttagt aaagaaaaaa
     2401 acgccactag aagctgtgaa aaactcaaaa gagttagtct accaagctat tttacaatct
     2461 gatagatacg gagtaaaaca aagttatgca aaatagtaag atacgacaaa tgagtttaac
     2521 agggatattg acagcattgg ttgttgtttt aggaagattt gtcatgctac ctactccaac
     2581 aggtttttta acgctgttgg atgcaggaat ttatgctgtc agcttttcct ttggatcagc
     2641 tcaaggagct attgtgggag ggttatcagg ttttttaatc gatttagtgg caggataccc
     2701 tcagtggatg tttcatagtt tgattgctca cagtgtccaa gggtattttg cgggatggag
     2761 agggcgcaag cgttggcttg gtgttgtgat aggttctttt atcatgattt tttggtactt
     2821 tttaggctct cttatgcttg gttatggcct ttcgggatct ttagccggta tttggggaaa
     2881 cgtcatgcaa aatacattag ggctttttgt tggttttatt atctttaagg ccatattaag
     2941 gcaaaaaaag agataaggag agtgagaagt tgttgaataa tttagagaaa caaacaaggg
     3001 aaatcgtcat tgatgttgta gaacgctctg ctattcaacc aggtaatctt tttgttctag
     3061 gtctttcatc tagcgaaatt ttgggtagta gaattggaaa acaatctagt ctagaagtag
     3121 gtcaaatagt tgttgaagtt gtgttagatg aattaaataa gcgtggtgtt catttggctg
     3181 tacaaggttg tgaacacgtc aatcgtgcct tggtagtaga gaggcatgtg gcagaatcta
     3241 agcagttaga gattgtcaat gtggttccga atcttcatgc tggtggcagt gctcagatgg
     3301 ctgcttttca atttatgtca gaccctgtcg aagtagaaga agttattgca cacgctggac
     3361 ttgatatagg tgatactgct ataggaatgc atattaagcg tgttcagatc cctctgattc
     3421 cttgtcaacg agagctagga ggtgctcatg tgacagcttt ggctagtcga ccaaaattaa
     3481 ttggtggagc tagggctgat tacaatatgg atattatccg taaatcctaa accctttttt
     3541 ctggaataaa acaattggtg ttttttctag aaaaaaggat tttttaagat tatattaaga
     3601 ttttgaggtg atagaatagc tgattgcagt cggtaattga atgccttctt tgagtaaagc
     3661 ttcttgataa agtctataaa aagtatggta aatcttaaat tgttctccat tttctgtgaa
     3721 aatagcaatt ctaaaagtga actgtccatt agagttattt tgaggcccta aaatatttgg
     3781 tttgccaacg atttgaggat ggtttggcaa ttccttttga ttcacttcat caatgattcg
     3841 agtgacttgg ctcaaattaa cagtggaata aagaggaatt tcaattaagg cacgcatatt
     3901 accacgagat ttgttgctga caacagtgat gctacggttt gggatgaaat gtagtgttcc
     3961 atcgaatcca cgaatttgag tagttctaat tccaacacca aagacactgc cttctatgtc
     4021 agagatagta acgttatctc ctacttcaaa ttgattctca aataagataa aaaagccatt
     4081 gacaacgtca gataaaaatc cctgtgcacc taacccgatt gctactccag caattccagc
     4141 tcctgctaga agactagaga caggtatgcc aaataagcta agtatccaat aaatgagaag
     4201 aaaatacaat aagtaattta aaatattgtg agtgagctta gagagtgttt ttttgcgagc
     4261 ttcactttgt cttgaataag caaacgattt gttaatggtt ttttcaaaaa gatagttagt
     4321 aacacgtttt aaaatagcaa aaaagagtaa tagaataatg agagacacta gctttttaaa
     4381 aatcgttaag ccaatatttt cgatatgaga ctgctctagg taatgtaata taaatgtcat
     4441 gagaaatcct ttctttgata gtttatcaaa aaaaaaccaa tcttgaaaag agataaatta
     4501 atattttaac caaagttatg ataattgttt tatcataaag aatgcca
//
LOCUS       DATWVB010000073         4472 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.073, whole genome shotgun sequence.
ACCESSION   DATWVB010000073 DATWVB010000000
VERSION     DATWVB010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4472
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.073"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(293..656)
                     /locus_tag="VCX65_001683"
                     /pseudo
     CDS             complement(293..656)
                     /locus_tag="VCX65_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1077..1610)
                     /locus_tag="VCX65_001684"
     CDS             complement(1077..1610)
                     /locus_tag="VCX65_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEP5054126.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            complement(1690..2466)
                     /gene="recX"
                     /locus_tag="VCX65_001685"
     CDS             complement(1690..2466)
                     /gene="recX"
                     /locus_tag="VCX65_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEP5054127.1"
                     /translation="MKITKIEKKKRLYLIELDNDDSLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIEDLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            2581..3936
                     /gene="rlmD"
                     /locus_tag="VCX65_001686"
     CDS             2581..3936
                     /gene="rlmD"
                     /locus_tag="VCX65_001686"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEP5054128.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFC
                     QITSVKRNFAEAKLLMVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLANFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
BASE COUNT         1343 a          718 c          933 g         1478 t
ORIGIN      
        1 ctatttagta actttggtta aagtaatcga actaacttgg ttgattgtat tttaatgata
       61 aaaagcttaa atttgttata caacaaattt aagcttttta ttgtttcttt ttaattgcag
      121 attgaggttt aaaagacact ttacaatgtt ctcaagtcat gtgttgttgt aggttgtatg
      181 cacatattac aaatcccatt atagaagaaa ttgtttaatt aatggatagt aatggatggt
      241 atggagatct taatgtggtt ttaatggtaa ttttagcagt tatagtaaga caaaaggtga
      301 cttggaaaag cttatgcaga cgattcttaa ctcccacaat atcttctgtc agattttatt
      361 agacttcttc tcagtgtcaa ttttgtctgt tttacgaacg tgcaggctat tcaattgctt
      421 cttagcttct aaaggattaa accgagtata agcgtagcca ttatctgcga aaaaacctga
      481 agacgacgag aatagacatt aatcgtttta aggataatct cagggttatg gacggttttc
      541 aagtttccaa gaagatgatt gaggccgatg gtatcgtttt gtcttgaatg attccttatt
      601 ttagtggttt cattttcaat acacgacgtc aagcgtccta catactttga taaaattcta
      661 cctaaaagag gtgtcttgtc agttttggtt acaacatcaa gtgccaaaag actttgcgac
      721 ttaacaagac acttctactt taacgcaaag aaaaagtagt gagtactctc tttcgtcgga
      781 gatttcctcg ctactaaact tagtattttt tgatactttc cttaggtagt gcttaaggca
      841 gcgactttct ttggaattcc atgccttatt tttgagatcc taggctcaaa aatgccaagt
      901 ggcgtcaaca ttaacattga cgccactttt accacaacga aaaacatctg ttttggctca
      961 ctccacacgc agaaatagga aattggatgt caaatcagca gagctgttca tgctttttga
     1021 gcctaaaact gagtttgtct gcgttctgag cactccttgg gagtgctgga caactcttaa
     1081 cgattcttca gttcaagata acgtttgtac caaatagtga tataggcctt ggaaaatggt
     1141 cctttttcat gattaatcca atcaaccaat attttgacat tttcttttag gataaagtcc
     1201 atatcggctg aatactgcat ctctttttta tgaatctcgt attcatcaac atcaagtaat
     1261 ctcttttcac catccgcaaa gactttgaca tctaaatcgt aatcaatgta tttgagggcc
     1321 tcagtgtcca tcatgtatgg actagctaag ttacagtaat aagagacgcc attatctcga
     1381 atcatggcta taatgttaaa ccagtatttt ttatgaaagt aaacgattgc aggttcgcgg
     1441 gtcacccatc gtctaccgtc actttctgtg acaagagtgt gatcattaac tccaatgagg
     1501 gcattttcag ttgtttttag taccatagta tcgcgccaag tacggtgcaa actaccatca
     1561 tgcttataac tttgaattgt aataaagtcg ccttctttag gtaatttcat gccttaccaa
     1621 ctttctacaa ttaaacttat cctctatagt ctatcataaa tgtgtgaaaa aatcacttct
     1681 tttgtcagtc tataaataat ttcttaactt gcaattaata tcgtcgctgt tgtagccttt
     1741 tcggtagaga gcctgataga gcttttgctt taaagtataa ccatcatatt tgcgactgag
     1801 tttacgatat tgtttgtcta attctttgtc aagaagatct tctatttctt gattatcttg
     1861 gtcaaaatta aggtgattga ggctatgttt agctagatcg tatgaaaagc ctttggtcag
     1921 taatgcttgg gtgattttat ctttcaaggc ttttggtggc aatttttctt gatatttgtc
     1981 aaagagtttt tggcttactt tttgagcgag ttggctaaag tcagtttgag ataagatagg
     2041 atcaatgtca tgacttgcaa tgcctttttg taataacttt tgttttaaga cttggggacc
     2101 tttatcacca tttaactgat tttggcgaat gtaggtatca gccaatttgg tgtcgtctat
     2161 ccattgttct tcttggagtt gagtgatgat gtcagcaata atgtgttctt caatctcatg
     2221 cttgcgcagg taatcagcaa cttgcttgtt gctgcgttgt tgaaaggaaa gaaaataaag
     2281 ggctaaattt ttgccgtagg acagttgggc aaaatgtttc atgtcttcaa gctgatcatt
     2341 gtcaaggact ttatctttac tcaacataaa ccgaacaata gtatcttctg ttacataaag
     2401 ggaatcgtca ttatccaatt cgataaggta gaggcgtttt ttcttttcaa ttttagtgat
     2461 tttcatatgt tcattatatc aaaaatggta aaatagaaga cgaaaatact gctaaaaatg
     2521 tgttgcttgt gaatgctttt ggtggtgaga ttaggatatt agaggaagta aggggaagag
     2581 atggtcgtaa aggttaaaca gaaaattcct ttaaaaatta agcgaatggg aattaacggt
     2641 gaggggattg gtttttatca gaaaactttg gtatttgtcc ctggtgcttt aaagggagaa
     2701 gatatttttt gccaaatcac gtcggttaaa cggaattttg cagaggccaa actgttgatg
     2761 gtaaacaagg cttctaagaa tcgtgtcaaa ccagcttgtt ctgtttatga aacttgtggt
     2821 ggttgccaaa tcatgcatct agcctatcct aaacagctag atttcaaaga tgatgtgatt
     2881 aggcaggccc ttaaaaagtt caaaccaact ggctatgaac aatttgagat tagaccgact
     2941 ttaggaatga aaaagccaga tcactatcga gccaaattgc agtttcagct gcggtcattt
     3001 ggcgggacgg tcaaggctgg tttattttcc cagggaagtc atcgcttggt tcctattgac
     3061 aattgcttgg tacaggatca actaacgcaa gatattatca ataagattac gcagttagtg
     3121 gacaagtaca agttgcccat ttacaatgag cgcaagattg ctgggattcg gacgataatg
     3181 gttcgtaagg cacaggctag tgatcaggta cagattattg ttgtgagtag caaagaagtt
     3241 cggttagcga atttcattgg cgaattgact aaggcatttc ctcaggttaa aacggttgcc
     3301 ttgaatagta atcgttctaa atcgagtgag atttatgggg acgaaacgga aattctatgg
     3361 ggacaagagg cgattcatga agaagtttta gactatggat ttgcgttatc accgagagct
     3421 ttttaccaac ttaatccaca gcagacagaa gttttgtatg gtgaggtggt gaaggccttg
     3481 gatgtaggga gcaaagatca tattattgat gcctattgtg gggttggctc gattggcttt
     3541 gcttttgcag ggaaggtcaa gtctgtgcgg gggatggata ttatcccaga agcgattgaa
     3601 gatgcacaaa aaaatgccaa agccatgggc tttgacaacg cttactatga ggcagggaag
     3661 gcagaggata ttattcctaa atggtataaa caaggttacc gcgcggatgc catcattgtg
     3721 gacccaccaa gaactggttt agatgataaa ttattaaaaa cgattcttca ttaccagcct
     3781 aaacagatgg tgtatgtgtc ttgtaatacc tccactttgg cccgcgactt ggtgcagcta
     3841 acaaaggttt acgatgttca ctatatccaa agtgtagaca tgttccccca tacagctagg
     3901 accgaggctg tcgtgaagtt acaaaaacgt gtatgattga gtggcaataa caactcaagt
     3961 tttataagct caggtaatgg gtttgagcaa tagcttgaca tagtagggat gtcaaaaacg
     4021 gtttactaag catagtcata ttattgataa ctctatgttt attttagaaa cattcatggt
     4081 taaaaaagtt tgttagtttg tcactacgta gggtttattt gaagagcaag tacacacaga
     4141 caatattagg ggaattggtt gttgaaaaaa agctgttttt tgctataaat tagaaaactg
     4201 agtggtcagg aggttacatt accagaagtt attttagtat gctaatatga acgatgatat
     4261 agaggattta tcctgattta atcttttaag ctgtaagaaa cctttgcaaa aactgtaggc
     4321 tgtgtgagtc tttatgtgtt agatattaaa gataaatgca acacttgttt ataatgagat
     4381 caacaactga taaatctgag ttgataacca gtaaaatgat cggaatatag aaaagttact
     4441 taatcaagct tttcgtaatt taactgttag aa
//
LOCUS       DATWVB010000074         4462 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.074, whole genome shotgun sequence.
ACCESSION   DATWVB010000074 DATWVB010000000
VERSION     DATWVB010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4462
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.074"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1138
                     /locus_tag="VCX65_001687"
     CDS             join(<1..237,237..1138)
                     /locus_tag="VCX65_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP5054129.1"
                     /translation="VLIDGQSQKQTSLDYALLTSSMLSRWIAQYKKNGYTILEKPRGG
                     PSKMGRKRKKNLEEMTEVERLQKELEYPRAENAVPKKAERIPLEGRSKAQRATEIIQA
                     LRNQFPLEMLLEILDLSRSTYYYQVKRLAQGDKDIELKHVIREIYDEHKGNYGYRRIH
                     MELRNRGFVVNHKKVQRLMKVMGLAARIRRKRKYSSYKGEVGKKADNLIKRHFEGSKP
                     YEKCYTDVTELALPEGKLYLLPVLDGYNCEIIDFTLSRSPNLKQVQTMLEKTFPADSY
                     SGTILHSDQGWQYQHQSYHDFLESKGILPSMSRKGNSPDNGMMDSFFGILKSEMFYGL
                     EKSYKTLDKLEEAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFQ"
     gene            complement(1438..2310)
                     /locus_tag="VCX65_001688"
     CDS             complement(1438..2310)
                     /locus_tag="VCX65_001688"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEP5054130.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLASGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            2534..3844
                     /locus_tag="VCX65_001689"
     CDS             2534..3844
                     /locus_tag="VCX65_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEP5054131.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLIAT
                     LLSALGAGFFTTMAICCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPVLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISTQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            3922..4215
                     /locus_tag="VCX65_001690"
     CDS             3922..4215
                     /locus_tag="VCX65_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP5054132.1"
                     /translation="MPRKTFDKAFKLSAVKLILEEEQSVKMVSSTLEIHPNSLYRWIQ
                     EYEKYGESAFPGHGSALRHAQFETKKLEKEHKLLQEELALLKKFQVFLKPNRK"
     gene            4248..>4462
                     /locus_tag="VCX65_001691"
     CDS             4248..>4462
                     /locus_tag="VCX65_001691"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP5054133.1"
                     /translation="MNSHHTCQTLQVSRSGFYAYLKRRLSSKHVENEALKEMIKDIFY
                     EHKERYGSVRITQELCRRGIHVNHKRVG"
BASE COUNT         1362 a          967 c          830 g         1303 t
ORIGIN      
        1 aagtcctgat tgacggccaa tctcagaaac aaacatcctt agattatgct ttactaactt
       61 ctagtatgct ctcaaggtgg atagcgcaat acaagaaaaa cggttatact attcttgaaa
      121 aaccaagagg gggaccgagt aagatggggc gtaaacgtaa gaaaaatttg gaagagatga
      181 cagaggttga acgtcttcag aaggaattag aataccctag agcggagaat gctgtgctaa
      241 aaaagctgag agaataccgc ttgagggacg aagtaaagct caaagagcaa cagaaatcat
      301 tcaagcatta aggaatcaat ttcccttaga gatgctactt gagatccttg atttatcacg
      361 ctccacctat tactatcaag tgaagcgact agctcaagga gataaggata tagaactaaa
      421 gcatgtgatt cgagagattt atgatgagca taaaggtaat tacggttatc gtcgtattca
      481 tatggagttg cgtaaccgag gatttgtggt caatcataag aaagttcaac gtctcatgaa
      541 agtcatgggc ctagcagccc gcattcgtcg gaagcgcaag tattcttctt acaaaggaga
      601 ggttggtaag aaggctgata atctgattaa acgtcacttc gaaggctcta aaccttacga
      661 aaaatgttac actgatgtga cggagttggc cttacctgaa ggaaaactct acttattacc
      721 tgttcttgac ggctataact gtgagattat tgatttcact ctgtctcggt ctcctaactt
      781 gaaacaggtt caaaccatgc ttgagaagac ttttccagcg gattcataca gcggaactat
      841 tcttcatagt gaccaggggt ggcaatacca acaccagtcc taccatgatt ttttagagtc
      901 taaaggtatt ctgccatcca tgtcccgcaa agggaatagc ccggataacg gcatgatgga
      961 ttccttcttt ggcattctca aatctgaaat gttttatgga ctcgaaaagt cttataaaac
     1021 ccttgacaag cttgaagaag ctattacaga ttacattttt tactacaaca acaaacgaat
     1081 caaagcaaaa ctaaaaggac ttagtcctgt ccaatacaga actaaatcct ttcaataatt
     1141 atttgtccaa ctttttgggg tcagtacact cctagttaac gactttgatt gattttatta
     1201 tgatgaatcg tgatttctga aaacaaaatt ttcttcatgg atttggcgtg gaacttttac
     1261 aataaaaaca ctaacctctc cctatcgttt tttcaggtga atgcttggaa ttggtataat
     1321 aagcggacac gaatcaggtg aaaacagaga aagtatttga agaggcgttt aaactatctg
     1381 acataaaact cgttctagag gaaagacatc ctttaaaaag ttagtttatt ttgcaactta
     1441 gacatcaagg taggttaaac ccttcatgga aaaatcgaga ctcttagcac tatgggttaa
     1501 actaccactg gagacgtaat caatcgctaa accacgaaaa cggctaatag tggtcatatc
     1561 aatatttcca gaacattcaa tccgagaacg tcctgcaatt agagtaatgg cctgttcaat
     1621 ctgttccaat gacatattat ccaacatgat aatatcaaca cccgccgccg cagcttcttc
     1681 ggcagcagca agactttcca cttccacctc gaccattttc acaaaagggg cataggcacg
     1741 cgcttgagca atcgcctttt gaacactacc tactgccgca atgtgattgt cttttagcat
     1801 gatagcatct gataaattaa agcgatgatt atagccaccg ccaactctca cggcatattt
     1861 ctcaaaaaga cgtaaattag gagtggtttt tcgagtatca aataccttaa tgcgatcatc
     1921 gcctaaggct tctacataag cagctgtcat cgaagcaatc cctgataaat gttgtaaaaa
     1981 attcaaggca acgcgttcac atgttaagag gcttctcacc gagcctatga tttctaaaac
     2041 caaatcgcca ctagccaaac gatctccatc cttaaattga tgaggattct ggaaggtcac
     2101 ctcggcatca aatagggtaa aaaccctttg aaaaacggtt agccccgcta aaacaccagc
     2161 ttccttggca aaaagcgaca ccttggcttg gccatgatga tcaaaaatgg cattggtact
     2221 gtaatcttcg gaatgaacat cttctcgcaa ggctgctttc aatgtatcat ctatttgaaa
     2281 aggggttaaa tcagttgaaa tgattgacat cactaagtcc tctattttta atatcacttg
     2341 taagcactag aggcaattgc tattaacttc cgtaggaaat cacaaacctg aatacctcgt
     2401 tttaaattcc aacaagtgtc aagacaattg taattttttt gtgtataata gtcaagtacc
     2461 aataggaaac aggtggtctt ttgagcgcca aaattgccaa cctatttaca tattctaact
     2521 aaaggacaat tcaatgattc atttaataat aattagcgcc attgctctag ccattggaat
     2581 tggttaccgc accaaaatca atattggcct actggctatt gctttttctt acctcatcgc
     2641 aaccactctc atgggattaa gccccaaaga acttcttcat ttttggccaa cctcactctt
     2701 ttttaccatt tttagcgtct ctctctttta taacgttgca acaactaacg gcactcttga
     2761 tgttttggct caacacattc tctaccgcac acgcacccac cctaacgccc tctacatgat
     2821 tttatacctg atagcaaccc ttttgtctgc tttaggtgct ggatttttca ctactatggc
     2881 catttgctgt cctctagcga ttaccctctg tcaaaaagcg gacaaacacc ctttgattgg
     2941 agctcaagcc gtcaattggg gagcttcagg aggggctaat ttgataacca gtggctcagg
     3001 cattgtcttt caaggcctgt ttaagcaaat gggatgggaa gagcaagctt tttcacttgg
     3061 caatcatatc tttatcgtca gcattatcta cccactcatc gtcttgcttt tattatcttg
     3121 ttacatccgc tacagtaagg gaagaacaaa ctcatccttg actattgacc aaccaccagt
     3181 cctcagcaag gtccaaagac aaaccacctt gctcatgatc agcagcatgg ttttggtttg
     3241 gctttttccc ttgttgcatc tcattttccc aaacatcgca tggatagcta cttatcgaca
     3301 aacatttgat attggctttg tctcaatact catggtctgc ctcgccttaa ggctcaaatt
     3361 agggaagcaa gaagccattt tggctaaggt tccctgggct ataattatca tgctctgcgg
     3421 catgagctta ctaatgtctc tagcggtcaa gtcaggttta gttacactga tagggcacct
     3481 cataacaaca accattcctc atttctggtt acctctgttc ttttgtgtga tagccggagt
     3541 gatgtcactc tttagttcca ccctatccgt tgtagcccca actctctttc ccatcattgc
     3601 taccatcagt actcaaagtc ctcacattga tattcgctta ctcacaacag ccactattat
     3661 tggcgctcta tctactaata tctctccttt ttcatcagct ggttccctca ttcaactctc
     3721 ccttccccat atagaggaac gcagtcttgc tttcaaaaaa caaattcttc tgggtgtgcc
     3781 catcagctta agtttggcac tcttgaccat ctggattctc atgctgctag cttccttaag
     3841 ttagatttat tgtctaacat ttggttggac ttggtatact aaagtagaca caaaattaag
     3901 tggaaacgag gaatagtcat tatgccaaga aaaacctttg ataaagcctt caaactctct
     3961 gctgtaaaac tcatccttga ggaagagcag tctgtaaaaa tggttagttc aactttagaa
     4021 attcatccca atagtcttta tcgatggatt caagaatatg aaaaatatgg agaaagtgcg
     4081 ttcccaggac atgggagcgc acttcgtcat gctcaatttg agacaaaaaa acttgaaaaa
     4141 gagcacaaac tgctacagga ggaattagct cttctaaaaa agttccaggt ctttttgaag
     4201 ccaaaccgga aataaaattt cagtttctga aggaaaatag tgttagcttg aatagtcatc
     4261 acacctgtca aactcttcaa gtctcccgtt caggtttcta tgcttattta aaacgtcgtc
     4321 tatcttcaaa gcatgttgag aatgaagctt tgaaggaaat gattaaagac attttctatg
     4381 aacataaaga gcgttacgga agtgtacgaa ttacccaaga actttgtaga cgtggcatcc
     4441 atgtcaatca taaacgtgtt gg
//
LOCUS       DATWVB010000075         4224 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.075, whole genome shotgun sequence.
ACCESSION   DATWVB010000075 DATWVB010000000
VERSION     DATWVB010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4224
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.075"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            156..251
                     /locus_tag="VCX65_001692"
     CDS             156..251
                     /locus_tag="VCX65_001692"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEP5054134.1"
                     /translation="MLKKYKYYFIFAALLSFKVVQELSAVDWWRL"
     gene            298..1296
                     /gene="ruvB"
                     /locus_tag="VCX65_001693"
     CDS             298..1296
                     /gene="ruvB"
                     /locus_tag="VCX65_001693"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEP5054135.1"
                     /translation="MARILDNDVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            1434..1871
                     /locus_tag="VCX65_001694"
     CDS             1434..1871
                     /locus_tag="VCX65_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEP5054136.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY"
     gene            1894..2295
                     /locus_tag="VCX65_001695"
     CDS             1894..2295
                     /locus_tag="VCX65_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054137.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKNGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            2292..4067
                     /locus_tag="VCX65_001696"
     CDS             2292..4067
                     /locus_tag="VCX65_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEP5054138.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNYSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMIGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGSLALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSKIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPKGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVEHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
BASE COUNT         1316 a          648 c          862 g         1398 t
ORIGIN      
        1 caaatgacag ctgatcagta tttggaaaac aagttaattc aagagtggga aaaagatgtt
       61 aaaagttatt aacaggacaa aaatgtcatt tttaaatatt taatagtaag atataattcc
      121 taatataaaa aataattatt aaggagtttt tatccatgtt aaaaaagtat aagtactatt
      181 ttatattcgc agctctacta tcttttaaag tagttcaaga gcttagtgct gttgactggt
      241 ggcgattata ataaaagtag gccactgctc tcttttactt tatgttataa tagtcctatg
      301 gctagaattt tagacaatga tgtaatggga aatgaggagt tttcggatcg gactcttcgc
      361 cctcaatatc tacacgaata tattggacaa gataaagtta aggaacaatt cgctattttt
      421 atagaagcag ctaaaagacg tgacgaatct ttagaccatg ttttattatt tggacctcca
      481 ggactgggaa aaacaacaat ggcatttgtg attgccaatg aattgggagt taatttaaag
      541 caaacttcag gtcctgccgt tgagaaagct ggagatttgg tagctatttt aaatgaatta
      601 gaaccagggg atattttgtt tattgatgaa attcaccgca tgccaatgtc tgttgaggaa
      661 gtactatata gtgctatgga agacttctat attgatatta tgattggcgc tggagatact
      721 agtcgtagta ttcatttgga tctgcctcca tttacattga ttggtgctac tacacgtgca
      781 ggcatgttat ctaatcccct cagagctcgt tttggtatca ctggtcacat ggaatactat
      841 caagaaaagg atttgacaga gattgtggag cgtacagcta ctatttttga aataaaaata
      901 gaccatgaag ctgcacggaa attagcttgt cgcagtagag gaacgccccg cattgctaat
      961 cgattactaa aacgagtgcg tgactatgct caaattattg gtgatggcat cataacggct
     1021 caaataactg atagagcttt gactatgtta gatgttgacc gcgaaggtct cgattacatt
     1081 gatcagaaaa ttttacgaac gatgattgag atgtatcagg gaggaccagt tggtttgggg
     1141 acattatctg tgaatattgc cgaggagcgt aatacagttg aagagatgta tgaaccctac
     1201 ttaattcaaa aaggctttct catgcgaaca cgaacaggtc gtgtagcgac tcaaaaggct
     1261 tatcgtcatc ttggctatcc ctatcaaaac acttaatgat ttttcaaatc taagaaaatt
     1321 aatctgaacc tgctttttgt gttcggattt tttgataagt tgacagaaaa ttattagatt
     1381 gatttctccg atatcagtta gaaatttgat ataataattc aaaggagtat ttaatgaaaa
     1441 aagtatgttt tgtctgtctg ggtaatattt gtcgaagccc catggctgag tttgtaatga
     1501 agtcaatagt atcaagtgat gttatgatga tagaaagtcg tgctacttct gattgggagc
     1561 atggaaaccc tattcactca ggtacacagt ccatattaaa aacttaccaa attaattatg
     1621 atataactaa atgctccaag cagataacta taactgattt taacaccttt gactatatta
     1681 ttggtatgga tagcgataat gtgaaaaatc tcaaagagat gtcgcaacat caatgggact
     1741 ctaaaatcta cctgtttaga gaagggggtg ttcctgatcc ttggtacact aacgattttg
     1801 aagaaaccta ccaattagtt agaaaaggat gccaggattg gctttctcgt ttaatgagta
     1861 aagagtattg atattagaag ttgagtaaaa gaaatgatag atatgcaaga tatagtaaaa
     1921 aaatggagta ttacacgggc gaagttggaa attgtctcgg tgattgtcat attggtttgt
     1981 gcaatttctg tttttagcgt aagaatttcg aataagacaa gtttgaccta tgataaaggg
     2041 cgtatgcact atactggtta cgtgatcaac cataaaatga atggagaagg gaagcttgtc
     2101 taccccaacg gtgatatcta tgagggtact tttaagaatg gcctatttga aggaaaagga
     2161 acttttactg ctaagacggg ctggttatat aacggggagt ttcataaagg acaagcaaat
     2221 ggcaaaggtg tgttaaaagc aaagaataat aaagtctata aagggatttt taaacagggg
     2281 atatttcaaa aatgagaata aaatggtttt cgtttgttag ggtaacagga cttttactgg
     2341 ttttactcta ccactttttt aaaaatgtat ttccaggagg ttttattggt gttgatattt
     2401 tcttcacctt ttcaggatat ctaatcacag ccctcttgat tgatgaatac acaaaaaaag
     2461 agtctatcga tattatcggt tttttaaaaa gacgctttta tcgaattgtt cctcctttgg
     2521 tgttaatgat tttattgacc attcctttta cgtttttaat taagaaggat ttcattgcta
     2581 atataggaag tcagattaca gctgttttag gatttaccac taatatttat gaaatattga
     2641 cgggaagtag ttatgaaagc caatttattc cacatctctt tgttcatacg tggagcttag
     2701 ctattgaagt tcatttttac ttgttgtggg gtgtatttgt ttggttatta gctagacgca
     2761 aggagactca gaaacaactg agaggactac tgtttttgat ttctttggga atatttgcta
     2821 ttagtttctt gagcatgttt ataagatctt ttatgacctc aaattattcc ctgatttatt
     2881 tttcgagtct ttctcacagt tttcccttct ttttaggggc gatgtttgcc acaataacag
     2941 gtattaacga gactactgtt cgatttcaaa aaaatgtacg tttatggccg cgccagtatg
     3001 tccttgctgc tatgattgga gcatttacac ttttgcttgt gctaacggtc acattggatt
     3061 ttaaccatat cacgacctat ctatttggct ttgctttggc tagcttattc gcatcaatta
     3121 tgatttatgc agcgcgtgtt cttcatgagc aaacaccaga tgtacaagag cctaaagcta
     3181 tcacttatat agctgatatt agctatggga tttacctctt ccattggcca ttttacatta
     3241 tttttagcca attaatgtct catattttgg cagttattct aacagttttc ttttcaatct
     3301 tgtttgccac tgtgtcttac tatattgtgg aacctttggt ccaagggaga aaaccaaacc
     3361 tgcttggttt agaaattgac tgttctcctt actataagtg gattgtagga gggtctctcg
     3421 ccttagcatt attaacttta ggaacttgta tgatagcgcc taaagttggt aagtttgaga
     3481 aacaattgtt ggtcagttcc ctacaacagg ctcaaagtaa tatggagcgg acacatacac
     3541 tagctgcagg agacgctaat gctttgagtg acgtaggtat tattggtgat tctgtagcat
     3601 tacgctctag tgcagcattc tcaaaaatta tgccacaagc gcaactggat gcagcggtca
     3661 gtcggaattt taaagaagct ttcgatttat ttaataacca aattaagtct aagagtctat
     3721 ctaagactgt tgtcttagca gtaggtgtta actcgcttga caactattct caagcagttc
     3781 agtcttttat tgaggcattg ccaaaaggac atcgtttagt tttggtttct ccatataatg
     3841 ccaaaaatgc cagtcaggtt gcagaagcta gagactatgg tcttaaattg tccaaaaaat
     3901 acaagtatgt cactattgca gactggtata aagttgctgt tgaacatcca gatatttggt
     3961 atggcagtga cggtgttcat tatagtgaag atagtcaagg agcagaacta tatgtctcca
     4021 caatccagac tgctgttgag aagtcagcta aaaaaccagc taaataaagt taagaaatgt
     4081 ctaagagata agtcagatcc attgtgctct ggctttttct tgtgaacaaa tgatgatggt
     4141 aaaatagtag tactttgagg tttttaaaag aaagcgattt cagaaataaa acggcttttt
     4201 ttagatatat ttctgaaaaa gagt
//
LOCUS       DATWVB010000076         4163 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.076, whole genome shotgun sequence.
ACCESSION   DATWVB010000076 DATWVB010000000
VERSION     DATWVB010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4163
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.076"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            327..590
                     /locus_tag="VCX65_001697"
     CDS             327..590
                     /locus_tag="VCX65_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEP5054139.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            595..2328
                     /gene="ptsP"
                     /locus_tag="VCX65_001698"
     CDS             595..2328
                     /gene="ptsP"
                     /locus_tag="VCX65_001698"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEP5054140.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            2513..3940
                     /locus_tag="VCX65_001699"
     CDS             2513..3940
                     /locus_tag="VCX65_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEP5054141.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALISGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLVLAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
     gene            4035..>4163
                     /locus_tag="VCX65_001700"
     CDS             4035..>4163
                     /locus_tag="VCX65_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deacetylase"
                     /protein_id="HEP5054142.1"
                     /translation="MKKLNLILVGLLSILILSLAIVFINRWKLNEDSQRIVLAEKKK"
BASE COUNT         1309 a          745 c          902 g         1207 t
ORIGIN      
        1 ataaagctaa aaagcaagct ataaacttat ctaaaacaca acatattgtg ttgaaataaa
       61 aaacagaaac ctaaatattg tgtcaatctg gattcttatg gttagagctc tagcgttttg
      121 gtgatagaag ctaagcagtt ttaataaagc attaaagtct gaaaaataaa ttgtgaaaaa
      181 cgtgaaaata aaagaaaata atttcacatt ttttgtcgtt taaatattta atcttgaaaa
      241 taaaaaagca ttgtgctata atcggttgtt gtaagggtta tcatgtgatg gctcaaaaat
      301 acacaactta aaaggagaac catactatgg cttcaaaaga ctttcacatt gttgcagaaa
      361 caggtattca tgcgcgtcca gcgactttgc ttgttcaaac agctagcaaa tttgcttcag
      421 acatcactct tgactacaaa ggtaaagcag taaatctaaa atcaatcatg ggtgttatga
      481 gtcttggtgt tggtcaaggt gcagatgtta ctatctcagc tgaaggtgca gatgctgaag
      541 atgccattgc agcaattgaa gaaacaatga ctaaagaggg attggcataa gactatgaca
      601 gaaatgctta aaggaattgc agcctcagac ggcgttgctg ttgctaaagc atatctacta
      661 gttcagccgg atttgtcatt tgagactgtt acagtcgcag atacaaatgc agaagaagct
      721 cgccttgatg ttgcactcca agctgcacaa gacgagcttt ctgttatccg tgaaaatgca
      781 gtagaaagct taggtgaaga agcagcagcc gtttttgatg cccatttgat ggttcttgct
      841 gatccagaaa tgatcagcca ggttaaagaa acgattcgcg caaaacaaac gaatgcagaa
      901 acaggtctta aagaagtgac tgacatgttc atcaccatct ttgaaggcat ggaagataac
      961 ccatacatgc aagaacgtgc agcggacatc cgcgacgttg caaaacgtgt gttggctcac
     1021 cttttaggtg taaaacttcc aaatccagct acaatcaatg aagaatcaat cgttatcgca
     1081 cacgatttga caccttcaga tactgctcaa cttaacaaac aatttgtaaa agcatttgtt
     1141 acaaatatcg gtggtcgtac aagtcactca gctatcatgg cacgtacact tgagatcgct
     1201 gcggtacttg gaacaaatga tattacaaaa cgtgttaaag atggtgatgt gattgccgtt
     1261 aatggtatca ctggtgaagt gattatcgat ccaagcgaag atcaagtact tgcttttaaa
     1321 gaagctggtg cggcttatgc caaacaaaaa gcagagtggt ctctccttaa agatgcgcac
     1381 actgaaacag ctgatggcaa acactttgaa ttggctgcta atatcggtac gcctaaagac
     1441 gttgaaggtg ttaatgacaa tggcgctgaa gctgttggcc tttaccgtac tgagttcttg
     1501 tacatggatt ctcaagactt cccaactgaa gacgaacaat acgaagctta caaagcagtg
     1561 cttgaaggca tgaatggcaa acctgttgtg gttcgtacaa tggatattgg tggagataag
     1621 gaacttcctt actttgacct tccaaaagaa atgaacccat tcctcggttt ccgtgctctt
     1681 cgtatctcca tctctgaaac tggggatgcc atgttccgca cacaaatgcg tgcgcttctt
     1741 cgcgcctctg ttcacggaca acttcgtatc atgttcccaa tggtagcact tcttaaagaa
     1801 ttccgtgctg caaaagcagt ctttgacgaa gaaaaagcaa acttgcttgc agaaggcgtt
     1861 gcggttgctg atgacatcca agttggtatc atgattgaga ttcctgcagc tgctatgctt
     1921 gcagaccaat ttgctaagga agttgatttc ttctcaattg gaacaaacga ccttatccaa
     1981 tacactatgg cagcagaccg tatgaacgaa caagtatcat acctttacca accatacaac
     2041 ccatcaatat tacgtttgat caacaatgtg atcaaagcag cgcacgctga aggtaaatgg
     2101 gcaggtatgt gtggtgagat ggcaggtgac caacaagctg ttccacttct tgttggaatg
     2161 ggcttggatg agttttctat gtcagcaact tcagtacttc gtacgcgtag tttaatgaag
     2221 aaacttgact ctgctaagat ggaagaatat gcaaatcgtg cgcttacaga atgttcaaca
     2281 gcagaagaag ttcttgaact ttctaaagaa tacgtttctg aagattaacg ggttaaagag
     2341 ttggtttaaa ccagctcttt tttgctagct aaaaatacaa ttactttttg gtgtgaaatc
     2401 atttgagtta tcaaataatt atcagaattt tcagatattt agtgtagcca aatcttgaat
     2461 tatatcagaa aagtgataga ataagattac tatcataaaa ggagataaaa cgttggcaaa
     2521 acaatataaa aatttagtga acggtgaatg gaaactatca gaaaacgaga ttaccattta
     2581 cgcaccagca acaggtgaag agttaggatc agttccagcg atgacgcagg cagaggtaga
     2641 tgctgtttac gcttcagcta aaaaggctct atcagattgg cgcgccttgt cttatgtgga
     2701 acgtgcagct taccttcata aagcggctga tattttagta cgtgatgctg aaaagatcgg
     2761 cgcgattctt tcaaaagaag tagccaaagg tcacaaggca gctgtcagtg aagttattcg
     2821 taccgctgaa atcattaatt atgcagcaga agaagggctt cgtatggaag gtgaagttct
     2881 tgaaggtggt agcttcgaag ccgcaagtaa gaagaagatt gctattgttc gtcgtgaacc
     2941 agttggttta gttcttgcca tctcaccttt taattatccc gttaacttgg caggttctaa
     3001 aattgctcca gcccttattt caggaaatgt tgttgctctt aaaccaccaa cacaaggctc
     3061 tatttctggt ttgttactag cagaagcttt tgcagaagct ggtattccag caggtgtctt
     3121 taataccatt acagggcgag gttctgttat tggggattac atcgttgagc acgaagcggt
     3181 taactttatc aactttacag gttctactcc aattggggaa ggaatcggta aattagcggg
     3241 tatgcgacca attatgcttg agcttggcgg taaggattct gctatcgttt tggaagatgc
     3301 agatcttgtt ttagcagcga aaaatattgt agccggtgct tttggttact caggacaacg
     3361 ttgtacagcg gttaaacgcg ttcttgtgat ggacaaggtg gcggatcaat tggcggctga
     3421 gattaaaaca cttgttgaaa aactaagtgt cggaatgcct gaagacgatg ctgatattac
     3481 accattaatt gatacatcag ctgctgattt tgttgaaggg ttgattaaag atgcaactga
     3541 taagggagct actgctttga cagcctttaa tcgtgaaggc aatcttattt cacccgttct
     3601 ctttgatcat gtgacaactg acatgcgttt ggcatgggaa gagccgttcg gcccagtatt
     3661 accaattatt cgtgtaacca ctgtagaaga agccatcaag atttctaatg agtctgaata
     3721 tggtttgcaa gcttctattt ttacaactaa tttcccaaaa gcttttggca ttgctgagca
     3781 attagaagtt ggaactgttc accttaacaa taaaacacaa cgtggaacag ataatttccc
     3841 attcttaggc gctaaaaaat caggtgcagg ggtacaagga gttaaatatt ctatcgaagc
     3901 tatgacaact gttaaatctg ttgtatttga tatccagtaa taaaaaaaat aaacaaaaag
     3961 ttaggttaac ttaacttttt gtttattttt ttaatgtttt ttgttacaat agtctataca
     4021 gatggaggca actattgaaa aaattaaatc ttattcttgt tggtttatta agcattctga
     4081 ttttgagttt agctattgtg tttattaatc gttggaaact aaacgaagat agtcagcgta
     4141 tagttttggc tgaaaagaaa aaa
//
LOCUS       DATWVB010000077         3851 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.077, whole genome shotgun sequence.
ACCESSION   DATWVB010000077 DATWVB010000000
VERSION     DATWVB010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3851
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.077"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..344
                     /locus_tag="VCX65_001701"
     rRNA            <1..344
                     /locus_tag="VCX65_001701"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            396..468
                     /locus_tag="VCX65_001702"
     tRNA            396..468
                     /locus_tag="VCX65_001702"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:429..431,aa:Ala,seq:tgc)
     gene            769..3671
                     /locus_tag="VCX65_001703"
     rRNA            769..3671
                     /locus_tag="VCX65_001703"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            3757..>3851
                     /gene="rrf"
                     /locus_tag="VCX65_001704"
     rRNA            3757..>3851
                     /gene="rrf"
                     /locus_tag="VCX65_001704"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1099 a          793 c         1080 g          879 t
ORIGIN      
        1 catcatgccc cttatgacct gggctacaca cgtgctacaa tggttggtac aacgagtcgc
       61 aagccggtga cggcaagcta atctcttaaa gccaatctca gttcggattg taggctgcaa
      121 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg
      181 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg
      241 tgaggtaacc tattaggagc cagccgccta aggtgggata gatgattggg gtgaagtcgt
      301 aacaaggtag ccgtatcgga aggtgcggct ggatcacctc ctttctaagg aaatggaaca
      361 cgtttatcgt cttatttagt tttgagaggt cttgtggggc cttagctcag ctgggagagc
      421 gcctgctttg cacgcaggag gtcagcggtt cgatcccgct aggctccatc aggatacaat
      481 cctactaaac ttaatacaag tgaagttgaa cacgcaactc acttcctagg aaaatagaca
      541 atcttccctt gtgtgcaagg cccacatggt cagattccta attttctaca gaagtttcgc
      601 taaagcgagc gttgcttggt atcctatata atagtccatt gaaaattgaa tatctatatc
      661 aaattccacg atctagaaat agattgtaga aaagtaacaa gaaaataaac cgaaaacgct
      721 gtgactattt gataagtttt ctagttttta aaaaaactag gttaataagg ttaagttaat
      781 aagggcgcac ggtggatgcc ttggcactag aagccgaaga aggacgtgac aaacgacgaa
      841 atgctttggg gagctgtaag taagcgctga tccagagatg tccgaatggg ggaacccact
      901 aactaatggt tagtatccat aactgttaag gttatgagaa ggaagacgca gtgaactgaa
      961 acatctaagt agctgcagga agagaaagca aacgcgattg ccttagtagc ggcgagcgaa
     1021 acggcaggag ggcaaaccga agtgtttaca cttcggggtt gtaggactgc gacgtgggac
     1081 tttaaaagga tagaagaatt acctgggaag gtaagccaaa gagagtaaaa gcctcgtatt
     1141 taaaattctt ttgagcccta gcagtatcct gagtacggcg agacacgtga aatctcgttg
     1201 gaatctggga ggaccatctc ccaaccctaa atactctcta gtgaccgata gtgaaccagt
     1261 accgtgaggg aaaggtgaaa agcaccccgg gaggggagtg aaatagaacc tgaaaccgtg
     1321 tgcctacaac aagttcgagc ccgttaatgg gtgagagcgt gccttttgta gaatgaaccg
     1381 gcgagttacg atatgatgcg aggttaagtt gaagagacgg agccgtaggg aaaccgagtc
     1441 ttaatagggc gatttagtat catgttgtag acccgaaacc atgtgaccta cccatgagca
     1501 ggttgaaggt gaggtaaaac tcactggagg accgaaccag ggcacgttga aaagtgcttg
     1561 gatgacttgt gggtagcgga gaaattccaa acgaacttgg agatagctgg ttctctccga
     1621 aatagcttta gggctagcgt cgatgttaag tctcttggag gtagagcact gtttgggtga
     1681 ggggtccatc tcggattacc aatctcagat aaactccgaa tgccaacgag atatcatcgg
     1741 cagtcagact gcgagtgcta agatccgtag tcgaaaggga aacagcccag accaccagct
     1801 aaggtcccaa aataactgtt aagtggaaaa ggatgtgggg ttgcacagac aactaggatg
     1861 ttagcttaga agcagctatt cattcaaaga gtgcgtaata gctcactagt cgagtgaccc
     1921 tgcgccgaaa atgtaccggg gctaaaacag tttaccgaag ctgtggatga cacaaaagtg
     1981 tcatggtagg agagcgttct atgtgtgaag aaggtgtacc gtgaggagcg ctggaacgca
     2041 tagaagtgag aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag
     2101 actaaggttt ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc
     2161 gaaaggtgta tccgatggcc aacaggttga tattcctgta ctagagtata tagtgatgga
     2221 gggacgcagt aggctaacta aaccggacga ttggaagagt ccggctaagc agtgaggtgt
     2281 aagatgagtc aaatgcttat ctttataaca ttgagctgtg atggggagcg aattttagta
     2341 gcgaagttag tgatgtcaca ctgccaagaa aagcttctag cgtttaatga tactctaccc
     2401 gtaccgcaaa ccgacacagg tagtcgaggc gagtagcctc aggtgatcga gagaactctc
     2461 gttaaggaac tcggcaaaat gaccccgtaa cttcgggaga aggggtgctg acttaggtca
     2521 gccgcagtga ataggcccaa gcaactgttt atcaaaaaca cagctctctg ctaaatcgta
     2581 agatgatgta tagggggtga cgcctgcccg gtgctggaag gttaagagga gggtttagcg
     2641 caagcgaaga tctgaattga agccccagta aacggcggcc gtaactataa cggtcctaag
     2701 gtagcgaaat tccttgtcgg gtaagttccg acccgcacga aaggcgtaat gatttgggca
     2761 ctgtctcaac gagagactcg gtgaaatttt agtacctgtg aagatgcagg ttacccgcga
     2821 caggacggaa agaccccatg gagctttact gcagtttgat attgagtatc tgtaccacat
     2881 gtacaggata ggtaggagcc attgacttcg ggacgccagt ttcgaatgag gcgctgttgg
     2941 gatactaccc ttgtgttatg gctactctaa cccagatagg ttatccctat cggagacagt
     3001 gtctgacggg cagtttgact ggggcggtcg cctcctaaag agtaacggag gcgcccaaag
     3061 gttccctcag attggttgga aatcaatcgc agagtgtaaa ggtataaggg agcttgactg
     3121 cgagagctac aactcgagca gggacgaaag tcgggcttag tgatccggtg gtaccgaatg
     3181 gaagggccat cgctcaacgg ataaaagcta ccctggggat aacaggctta tctcccccaa
     3241 gagttcacat cgacggggag gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg
     3301 tagtcggtcc caagggttgg gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga
     3361 acgtcgtgag acagttcggt ccctatccgt cgcgggcgta ggaaatttga gaggatctgc
     3421 tcctagtacg agaggaccag agtggactta ccgctggtgt accagttgtc ttgccaaagg
     3481 catcgctggg tagctatgta gggaagggat aagcgctgaa agcatctaag tgcgaagccc
     3541 ccctcaagat gagatttccc atgattttat atcagtaaga gccctgagag atgatcaggt
     3601 agataggtta ggagtgtaag tgtagcgata catgtagcgg actaatacta atagctcgag
     3661 gacttatcca aaaagaaata ttgacaacgt tacggattct tgttagacta tagatattca
     3721 attttgagtg ggttatgaaa atagcacatt tacaagttaa gtgacgatag cctaggagat
     3781 acacctgtac ccatgccgaa cacagcagtt aagccctaga acgcctgatg tagttggggg
     3841 ttgccccctg t
//
LOCUS       DATWVB010000078         3819 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.078, whole genome shotgun sequence.
ACCESSION   DATWVB010000078 DATWVB010000000
VERSION     DATWVB010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3819
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.078"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            31..1254
                     /locus_tag="VCX65_001705"
     CDS             31..1254
                     /locus_tag="VCX65_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEP5054143.1"
                     /translation="MPSMKYILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            1313..2119
                     /locus_tag="VCX65_001706"
     CDS             1313..2119
                     /locus_tag="VCX65_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEP5054144.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPII
                     KAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLL"
     gene            2352..3707
                     /gene="dnaA"
                     /locus_tag="VCX65_001707"
     CDS             2352..3707
                     /gene="dnaA"
                     /locus_tag="VCX65_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEP5054145.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
BASE COUNT         1358 a          657 c          644 g         1160 t
ORIGIN      
        1 gctatggaca aataattcgg aggacaaaac atgccaagta tgaaatatat cttaaaatcc
       61 ttaagtattt tactaattgg atttttagga ggattaatag caattattac attcaataat
      121 ctctacccac attctccttc aaaaataaat tcaggtaagg caacaactag taatatggtt
      181 tttaacaaca caaccaatac tactaaagct gtcaaagctg ttcaaaatgc agttgtatca
      241 gttattaatt atcaagataa cccttcttca tccctttcta acccttatac aaaactcttt
      301 ggagaagggc gttcaaaaga gaataaggat gctgaattat ctatttttag tgaaggatct
      361 ggggtcattt atcgaaaaga tggcaactcc gcttacgttg ttactaataa ccatgttatc
      421 gacggagcta aacgaattga aattcttatg gcagacggat ctaaagttgt tggtgaatta
      481 gttggagctg atacttattc ggatttagct gttgttaaga tctcttcaga taagataaaa
      541 acagtagctg aatttgcaga ctctacaaaa ctaaatgttg gagaagttgc tattgctatc
      601 ggcagcccac taggaacaca atacgctaat tctgttactc aaggaatcgt ctctagttta
      661 agtcgtactg taactttaaa aaacgagaat ggtgagactg tctcaacaaa tgctattcag
      721 acagatgctg ctattaaccc tggaaactct ggtggaccac taattaatat tgaggggcaa
      781 gtaatcggaa ttaattcaag taaaatttct tctaccccaa ctggtagcaa cggtaatagt
      841 ggtgctgttg aaggaattgg ttttgctatc ccatctactg acgttattaa aattattaaa
      901 caactagaaa ctaatggtga agttatcaga cctgctcttg gaatatccat ggtcaattta
      961 aatgacttat ccacaaatgc tcttagccaa attaatattc caactagtgt aactggtggt
     1021 attgtagtag cagaagttaa ggaaggaatg ccggcatctg gcaaacttgc tcagtacgat
     1081 gtgattacag aaattgatgg caaaacagtt aattcaatta gtgatttaca aagtagtcta
     1141 tacggacacg atattaatga tactattaaa gtaacttttt atagaggaac tacaaagaaa
     1201 aaagcagata tcaaattaac aaaaactact caagatttga ctaaaacgca gtaaacaagc
     1261 tacctaaata ctattacatt ttatcacata aaacagtcca aaggactgtt ttatgtttct
     1321 tattctatcc aggaactccc ttatgacaaa agaattattg atagacctac caattgaaga
     1381 tattgttaca aatccctatc aaccaaggat acaatttaat caaagagaac tccaagacct
     1441 agcaacttct attaaatcaa acggcctcat tcaacctatt attgttcgaa aatctgacat
     1501 ttttggctat gagttagttg ctggagaacg acgacttaaa gcttcaaaaa tggctggtct
     1561 aaaaaaagtt ccagctatca tcaagaagat ctctacactc gagagtatgc aacaagctat
     1621 agttgaaaat ttacaacgtt ctaaccttaa cgctatcgaa gaagctaaag cctatcagtt
     1681 attggttgaa aaaaaacaca tgactcacga tgagattgct aaatatatgg gaaaatcaag
     1741 accttatatt agcaatacct tacgtctgtt acaactccca gcacctatca ttaaagcaat
     1801 tgaagaagga aaaattagtg cgggacacgc gcgtgctctt ttaactttga gtgatgataa
     1861 gcaacaactg tacctcactc ataaaataca aaatgaaggc ctaagtgtta ggcaaattga
     1921 gcaactggtt acttctactc caagttcgaa gctatctaaa aaaactaaaa atatttttgc
     1981 cacttcttta gagaaacaat tggctaaatc attgggactc tctgtcaata tgaagctgac
     2041 agcaaaccat agtgggtacc ttcagatatc tttttccaat gatgatgaat taaacagaat
     2101 tatcaacaag ctactttagc ttgttgatat tctgtttttt cttttttagt tttccacatg
     2161 aaaaatagtt gaaaacaata gcggtgtcac attaaaatgg cttttccaca ggttgtggag
     2221 aacccaaatt aacagtgtta atttattttc cacaggttgt ggaaaaacta actattatcc
     2281 atcgttctgt ggaaaactag aatagtttat ggtagaatag tgctagaatt atccacaaga
     2341 aggaacctag tatgactgaa aatgaacaaa ttttttggaa cagggtcttg gaattagctc
     2401 agagtcaatt aaaacaggca acttatgaat tttttgttca tgatgcccgt ctattaaagg
     2461 tcgataagca tattgcaact atttacttag atcaaatgaa agaactcttt tgggaaaaaa
     2521 atcttaaaga tgttattctt actgctggtt ttgaagttta taacgctcaa atttctgttg
     2581 actatgtttt cgaagaagac ctaatgattg agcaaaatca gaccaaaatc aatcaaaaac
     2641 ctaagcagca agccttaaat tctttgccta ctgttacttc agatttaaac tcgaaatata
     2701 gttttgaaaa ctttattcaa ggagatgaaa atcgttgggc tgttgctgct tcaatagcag
     2761 tagctaatac tcctggaact acctataatc ctttgtttat ttggggtggc cctgggcttg
     2821 ggaaaaccca tttattaaat gctattggta attctgtact attagaaaat ccaaatgctc
     2881 gaattaaata tatcacagct gaaaacttta ttaatgagtt tgttatccat attcgccttg
     2941 ataccatgga tgaattgaaa gaaaaatttc gtaatttaga tttactcctt attgatgata
     3001 tccaatcttt agctaaaaaa acgctctctg gaacacaaga agagttcttt aatactttta
     3061 atgcacttca taataataac aaacaaattg tcctaacaag tgaccgtaca ccagatcatc
     3121 tcaatgattt agaagatcga ttagttactc gttttaaatg gggattaaca gtcaatatca
     3181 cacctcctga ttttgaaaca cgagtggcta ttttgacaaa taaaattcaa gaatataact
     3241 ttatttttcc tcaagatacc attgagtatt tggctggtca atttgattct aatgtcagag
     3301 atttagaagg tgccttaaaa gatattagtc tggttgctaa tttcaaacaa attgacacga
     3361 ttactgttga cattgctgcc gaagctattc gcgccagaaa gcaagatgga cctaaaatga
     3421 cagttattcc catcgaagaa attcaagcgc aagttggaaa attttacggt gttaccgtca
     3481 aagaaattaa agctactaaa cgaacacaaa atattgtttt agcaagacaa gtagctatgt
     3541 ttttagcacg tgaaatgaca gataacagtc ttcctaaaat tggaaaagaa tttggtggca
     3601 gagaccattc aacagtactc catgcctata ataaaatcaa aaacatgatc agccaggacg
     3661 aaagccttag gatcgaaatt gaaaccataa aaaacaaaat taaataacat gtggaaaaga
     3721 atatctttta tgaaatagtt atccacaagt tgtgaacaac catttagtct tggattctct
     3781 cgtttattta gagttatcca ctatatacac aagacctac
//
LOCUS       DATWVB010000079         3342 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.079, whole genome shotgun sequence.
ACCESSION   DATWVB010000079 DATWVB010000000
VERSION     DATWVB010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3342
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.079"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            12..1661
                     /locus_tag="VCX65_001708"
     CDS             12..1661
                     /locus_tag="VCX65_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115157939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-like surface protein"
                     /protein_id="HEP5054146.1"
                     /translation="MFRRSKNNSYDTSQTKQRFSIKKFKFGAASVLIGLSFLGGVTQG
                     NLNIFEESIVAASTIPGSAATLNTSITKNIQNGNAYIDLYDVKNGLIDPQNLIVLNPS
                     SYSANYYIKQGAKYYSNPSEITTTGSATITFNILDETGNPHKKADGQIDIVSVNLTIY
                     DSTALRNRIDEVINNANDPKWSDGSRDEVLTGLEKIKKDIDNNPKTQIDIDNKINEVN
                     EIEKLLVVSLPDKIKYSPEAKHRTVEQHAELDAKDSIANTDELPSNSTYNWKNGHKPD
                     TSTSGEKDGIVEVHYPDGTVDDVNVKVTVTSKKTDNTAPTLTVTPEQQTVKVDEDITF
                     TVTVEDENEVELGLDDLKAKYENDIIGARVKIKYLTKEPNKKVMEVTIMKATLADKGA
                     ITFTAKDKAGNQAEPKTVTINVLPLKDSNEPKGKDQTVKVGETPKAEDSIGNLSDLPK
                     GTTVAFEAPVDTATPGDKPAKVVVTYPDGSKDTVDVTVKVVDPRTDADKNDPAGKNQQ
                     VKGKGNKLPATGENATPFFNVAALTIISSVGLLSVSKKKED"
     gene            complement(2167..2316)
                     /locus_tag="VCX65_001709"
                     /pseudo
     CDS             complement(2167..2316)
                     /locus_tag="VCX65_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            2373..2666
                     /locus_tag="VCX65_001710"
     CDS             2373..2666
                     /locus_tag="VCX65_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEP5054147.1"
                     /translation="MSTVAVRVDDQLKDDATELFQSLGLDMSTAVKMFLIQSVKTQSI
                     PFEIKNQSSVSDEEFQNLVETKLKGIRVKASDPESVNAFFGDEDFSEYEEYFK"
     gene            2663..3001
                     /locus_tag="VCX65_001711"
     CDS             2663..3001
                     /locus_tag="VCX65_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054148.1"
                     /translation="MSDIEVYSVLVSRIEYSDGTGSKVRPAVVVKFNDEVIKTLRLTT
                     KYENKSDNIKSQYLEVIDWAKANLKRRSWIDTIQYYDLEDKGFNIKIIGKLSDRDIER
                     LKDFLRAKEV"
     gene            3004..>3342
                     /locus_tag="VCX65_001712"
     CDS             3004..>3342
                     /locus_tag="VCX65_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054149.1"
                     /translation="MKKKLVGFIVLALSTIILVACSNDSLEGEYYWINDARNQHMATI
                     KGDKGYVESEGGYSIKIDSELKIIESKFGSEKYSYKDGKLTTNFTGVESDFYKKGSKA
                     CEEALKKYGYK"
BASE COUNT         1236 a          433 c          639 g         1034 t
ORIGIN      
        1 aggagaatat tatgtttaga aggtctaaaa ataacagtta tgatacttca cagacgaaac
       61 aacggttttc aattaagaag ttcaagtttg gtgcagcttc tgtactaatt ggtcttagtt
      121 ttttgggtgg ggttacacaa ggtaatctta atatttttga agagtcaata gttgctgcat
      181 ctacaattcc agggagtgca gcgaccttaa atacaagcat cactaaaaat atacaaaacg
      241 gaaatgctta catagattta tatgatgtaa agaatggatt gattgatcct caaaacctca
      301 ttgtattaaa tccatcaagc tattcagcaa attattatat caaacaaggt gctaaatatt
      361 atagtaatcc gagtgaaatt acaacaactg gttcagcaac tattactttt aatatacttg
      421 atgaaactgg aaatccacat aaaaaagctg atggacaaat tgatatagtt agtgtgaatt
      481 taactatata tgattctaca gctttaagaa ataggataga tgaagtaata aataatgcaa
      541 atgatcctaa gtggagtgat gggagtcgtg atgaagtctt aactggatta gaaaaaataa
      601 aaaaagatat tgataataat ccaaaaacac aaatagatat tgataataaa attaatgaag
      661 tcaatgaaat agagaaattg ttagttgtat cgctaccaga taaaattaag tattcgccag
      721 aggctaagca taggactgtt gaacaacacg cggaattaga tgcaaaagat agcattgcaa
      781 atacagatga attgccatca aattcaacgt ataactggaa aaatggtcat aaaccagaca
      841 cctcaacatc aggtgaaaaa gacggaattg ttgaagttca ctatccagat ggtactgttg
      901 atgatgtgaa tgttaaagta accgttacat cgaaaaaaac tgataataca gctccaacat
      961 taaccgtcac tccagagcaa cagactgtta aagtggatga agatattacc tttacggtta
     1021 cagttgaaga cgaaaatgaa gttgaactag gtttagatga tcttaaagct aagtatgaaa
     1081 atgatatcat tggagctcgt gttaaaatta agtatcttac taaagaacct aataagaaag
     1141 tcatggaagt gacaattatg aaagctactt tagcagataa gggcgcaatt acctttactg
     1201 caaaagataa agcaggtaat caagcagaac ctaagacagt taccatcaat gttcttccgc
     1261 ttaaggatag caacgaacca aaaggtaagg accaaacggt caaagtagga gaaacaccga
     1321 aggcagaaga ttctattggt aacttatcag atcttccgaa aggtacaaca gtagcctttg
     1381 aagctccagt tgatacagca acaccgggag acaaaccagc aaaagttgtt gtgacttacc
     1441 cagatggttc aaaagatact gtagatgtga cggttaaggt tgtcgatcca cgtacagatg
     1501 ccgataagaa tgatccagca ggtaaaaatc agcaagtcaa aggtaaagga aataaactac
     1561 cagcaacagg tgagaatgca actccattct ttaatgttgc agctttgaca attatatcat
     1621 cagttggttt attatctgtt tctaagaaaa aagaggatta atcttttgac ctaaaatgtc
     1681 actaaacttt tcaccattta ttggtgtgaa cacattaata aagttatgta tctctctcca
     1741 acaaacttaa ttaaagtatt tcaatttttc gagtttaatt cttgaaaaag cctatcgaga
     1801 ttattaattt cgataggctt ttgattttgt gtaagcgtcc aataacgagg tatcttccat
     1861 tttcttccct attccgtaag catccaatat accttgttat tggacgctta ctataaaact
     1921 gaagaaatga tcctatttag ttgaaatttg taaatgaagt gtatcattag agcctaagat
     1981 gttaatccta ggctctcttt tgttgattta aaatttttag gtgtaatcaa atgtaaggtt
     2041 agatgcaaaa ttttctaaaa tgactgtttg tcttttcaag taattaaatg tatttaaggg
     2101 gaatttataa aaataaaagg agtgtgtcaa taatgttgtg taaacacact ggcaaagctg
     2161 ggattgttaa tcaaataggc tttcaagtgt gtctgtacaa tgaccaaaac ctttgtggac
     2221 tcgttgttct tgcttgaagt tgtaatcatt aaatagtgtg actagacagt gttctagggt
     2281 ctcttcactg ggaaatacga ttttcttttt tgtttgcgtt gtattgcagt tagtgataca
     2341 atggttatac aaaaatgatt tgaggtgata ttatgtcaac agtagcagta agagttgatg
     2401 atcaattaaa agatgatgct acagaacttt ttcaatcctt agggttggat atgagtacag
     2461 cagtaaaaat gtttttgatt cagtctgtta aaactcaaag tattcctttt gaaataaaaa
     2521 atcaatcatc tgtttctgat gaagaatttc aaaatttggt agaaacaaaa ttaaaaggaa
     2581 tacgagttaa ggctagtgat ccagaaagtg taaatgcgtt ttttggagat gaagattttt
     2641 cagaatatga ggaatatttt aaatgagtga tattgaggta tattctgtat tagtttcacg
     2701 tattgaatat tctgatggta caggttcaaa ggttcgtcct gctgtagtag tcaaatttaa
     2761 tgatgaagta ataaaaactt taagattaac tactaaatat gaaaataagt ctgacaatat
     2821 aaaaagtcag tatttagaag ttattgattg ggcaaaagca aatttaaaaa ggcgttcatg
     2881 gattgataca attcagtact atgatttaga ggacaaggga ttcaatatta aaattattgg
     2941 taagttaagt gatagagata ttgaaagatt aaaagatttt ctcagagcaa aggaagttta
     3001 gttatgaaaa agaaattagt tggttttatt gttctagctt tatctacaat aattttggta
     3061 gcatgttcta atgattcact tgaaggtgaa tattattgga ttaatgatgc tagaaatcag
     3121 catatggcta caattaaagg cgataagggt tatgttgaat cagaaggcgg ttattccata
     3181 aaaattgatt cagagttaaa aattattgaa agtaaatttg gttctgaaaa atatagttat
     3241 aaggatggaa aattgacaac aaattttact ggtgtagaaa gtgattttta taaaaaggga
     3301 tcaaaagctt gtgaggaagc attgaaaaaa tatggttata aa
//
LOCUS       DATWVB010000080         3106 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.080, whole genome shotgun sequence.
ACCESSION   DATWVB010000080 DATWVB010000000
VERSION     DATWVB010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3106
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.080"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            841..1974
                     /locus_tag="VCX65_001713"
                     /pseudo
     CDS             841..1974
                     /locus_tag="VCX65_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            2236..2541
                     /locus_tag="VCX65_001714"
     CDS             2236..2541
                     /locus_tag="VCX65_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HEP5054150.1"
                     /translation="MEKSTLKLKPDFIGKAWYEKLGNAPRRIDGEAGQFQRHIVSNEK
                     HGVFHVITPALAQVFKTDDVVEIDGEAIFFEDRALNGNSVAPALNVRATGLKLAGGK"
     gene            2544..2999
                     /locus_tag="VCX65_001715"
     CDS             2544..2999
                     /locus_tag="VCX65_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP5054151.1"
                     /translation="MAKVGLNFGEKIQIVDKSYRVLNDGLVDLKEIFGDLSFRSFEET
                     DLIYEDDMTQPRRQDGSYPQIPTGESRGLVVGIFSPVQQQTEFVTLVDMSLAEFEALQ
                     LKYREPVELEGIIVTYSSVGSNQFKLFASKIKRSVSQKVANEGNHKQEK"
BASE COUNT         1003 a          575 c          664 g          864 t
ORIGIN      
        1 ccagaggctc ctcaaaagcc aacagatgat gttccaaact tagagaagga aaagccggta
       61 ccaccaactc cagttaaacc agaggcagtt aaacctgttt tagaacaaga aaaaccagtc
      121 ccagaagctc ctcaaaagcc aacagatgat gttccaaact tagagaagga aaaaccagta
      181 ccaccaaccc cagttgaacc tgaagcaatt aagccagatc tccaaagctt tacgccagag
      241 gtttatgacc cgattaaacc agttgtgaaa ccccatgtca ccgttcctga aaaggtcgtc
      301 tatgaggtta tggttcatcc tgttcaagtg aaacaaacgc caacaaatgt taagtctgtt
      361 actaatagtg atcaggttaa tatcgatgga caactggtac caaaaggatc aacggtaacg
      421 tgggagcttg ttaatacttc tctcaaagct ggtcgtcagg acatcacaag ctatgaacta
      481 actgatccac taccagatgg ttttgagtta gatgttaccg ccacacaaac cctttctcct
      541 gaatgggtga taacaacgga tgaagcaggc aaggttagtc ttaaggcttc tcaatccctt
      601 ttggctcact tcaatgctaa acgtgatcaa gatgtagaag tccctaaggt atcactggtt
      661 ggtcgtttac tgaatgatgc ggggacttat cacaatacct ttaagacggt ggtcactact
      721 ccaactggta gctacacggt aatctctaac acaccagtga tctatacacc agggaacgat
      781 ccgaaaacac ctcgtaaccc aggaggagat aatccaacac cgcatgataa tctgattcag
      841 ccaactaaaa ccattgtgga cgacaagggt cagtccattg atgggaagtc tgtcttgcca
      901 aacagcacgc tgacttacgt ggctaagcaa gattttgatc agtacaaagg gatgacagct
      961 gccaaagaaa gtgtcatgaa aggctttatc tatgtcgatg attacaagga tgaagcgata
     1021 gatggtcatt cactcgttgt gaattccatt aaggccgcta acggagatga tgtaaccaat
     1081 ctcttagaga tgcgccatgt gttatctcaa gatacgcttg acgataagct aaaagcactc
     1141 atcaaggcat caggcatttc tccagtcggt gaattttaca tgtgggtagc taaagaccca
     1201 gcagcctttt acaaagctta tgttcaaaaa gggttagaca ttacctacaa cttgtccttt
     1261 aaacttaaac aggactttaa gaaaggtgac attactaacc aaacctacca aattgatttt
     1321 ggaaacggat actacggtaa tatcgtggta aaccatctgt ctgaactaac tgttcataag
     1381 gatgttttcg ataaagaagg tggtcaatca atcaatgctg gcactgttaa agttggtgat
     1441 gaggtcacct atcgcttgga aggttgggtt gttccgacta accgtggcta tgacttgaca
     1501 gaatacaaat ttgtggatca gcttcagcat acgcatgacc tctaccagaa agacaaggtc
     1561 cttgcgacgg ttgatattac tttatcagat ggtagtgtta tcactaaagg tactgactta
     1621 gcgaaatata ctgagacagt ttacaataag gaaacaggtc actatgaatt agcgttcaag
     1681 caagacttct tagctaaggt cgttcgttct agcgaatttg gtgcagatgc ttttgtggtt
     1741 gttaaacgca tcaaagcagg tgatgtggca aatgagtata ccttgtatgt caacggtaat
     1801 cctgtgaagt ctaataaagt caccactcat acgccagaac aacctcaacc tgtaactcct
     1861 aaagcaccag ctttaccatc cacaggagag caaggagtat ctatcttaac ggcgcttggg
     1921 gccgctttac tctcactctt aggttatgta gggcttaaaa agcgtcaaca gtaagttatt
     1981 aatggataag ccatcaaagt agattacttt gggtctatcc attctctcta gcaagtaact
     2041 attaggggga tctcctttcc cttcaaaaaa ctagccgaaa aagtttacta ttggttactt
     2101 gttagggtga gtggatagat cttggtttat cactagaata gtgaccgaaa agtcaaaaaa
     2161 ctaagtggta aggctaggaa ataattgata agacaatcct agccttttta ttttaaaaat
     2221 gaaaagaggt aaattatgga gaaatcaaca ttaaagttaa aaccagattt tattggtaaa
     2281 gcatggtatg aaaaattagg aaatgctccc cgtcggattg atggcgaagc agggcagttt
     2341 cagcgtcata ttgtgtcgaa tgaaaagcat ggggtttttc atgtgattac accggcttta
     2401 gcccaagtat ttaaaacaga tgatgtagtt gaaattgatg gtgaagctat cttttttgaa
     2461 gatagagctt tgaatggtaa tagtgtagca cctgcactta atgtacgtgc aacaggattg
     2521 aaattagctg gaggtaaata gtaatggcaa aagtaggttt aaattttgga gagaaaattc
     2581 agattgtaga taaaagttat cgcgtattaa atgatggttt agttgacttg aaagaaattt
     2641 ttggtgactt atcatttcga tcctttgaag aaacagattt aatttatgaa gatgatatga
     2701 ctcaaccaag acgtcaagat ggttcttacc cacaaattcc tacaggcgaa tcacgtggac
     2761 ttgttgttgg tattttctca ccagtgcagc aacaaacaga atttgttact ttggttgata
     2821 tgagccttgc ggagtttgaa gcgttgcagt tgaaatatcg tgagccagtt gaattagaag
     2881 gtattatcgt gacttattct tctgtaggaa gtaatcagtt taagttattt gcttccaaaa
     2941 ttaaacgctc tgttagccaa aaagtagcta atgaaggtaa tcataagcaa gaaaaataaa
     3001 taataaggga gaggtaagat gcgtttactg cctgaatata gagggattaa ggtaaaacca
     3061 tatatgaggt atatgagtta ttaccttttt tcttttctat ttattt
//
LOCUS       DATWVB010000081         2898 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.081, whole genome shotgun sequence.
ACCESSION   DATWVB010000081 DATWVB010000000
VERSION     DATWVB010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2898
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.081"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..1524
                     /locus_tag="VCX65_001716"
     CDS             <1..1524
                     /locus_tag="VCX65_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HEP5054152.1"
                     /translation="ENIYLLREKTHKLFYSEFENQLFETIMFLSMKTLVLDINHFSKE
                     IENKSEAYEQCIQQIREENGINHFFDRYPYLLKQINKEVGLIEESYSLLFDRFLEDLS
                     EIRSCFNISEPLSNVAFSLGDSHSKKQTVVKIAFKEKSVYYKPKSYHSHSILLELTSL
                     LKSSNIPSFSLPKSLVKADYCWQLGVAYTSSNKDEVAKIYFKYGVLAAFSEIFSITDL
                     HMENVIVSGGDLYLIDVETFFQRKLNVQNQNFEGITVDTYQRIYETSLSNGLFPVQFE
                     KNSAPNVSGISGKGGKRKKGKYELINKNRGDMKLVKVDYFQEDGFNIPTLNGKVVEPL
                     DYANEIISGFRECYIFLLSQRSKIKGIVEGFPELKSRALFRNTSDYGKFLQASTNPKY
                     LFSEKKKKNLFSILYEAKHIEHFIVDNEIKDLMNGDIPYFSMDTRGNVYNSVGTLIGN
                     LGDTTSLFDSITILNDERLKFTCELLEIVLKKPIKHWEREKGKSYQFLSISSEHYLL"
     gene            1526..2059
                     /locus_tag="VCX65_001717"
     CDS             1526..2059
                     /locus_tag="VCX65_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5054153.1"
                     /translation="MDKTDFRNISAFVSQDSPMFDGDVMYNISLGRESVSGEQVIETC
                     KRVSIYDDIRSMPMKFHTPLFRDNPSLSGGQKQRISLARELVTTPRILVLDEPTSALD
                     VKTERIIQKNVEALHCTRILVTHRLNTVEKADKILIMDNGKIIDYGNHHYLYKNNKDY
                     CDLYDSYMNKYQEEEVK"
     gene            2056..2793
                     /locus_tag="VCX65_001718"
     CDS             2056..2793
                     /locus_tag="VCX65_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5054154.1"
                     /translation="MKQLVLKDVCKKYPNQLNYALDHINLIVEKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGSIYCADKEISAFSDNEATSFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNVDSSKIDDLINNYAKRFNLYEQLKKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEGTMRILSEINKIEKVTILMVTHDVLSASYADRVVLLKDGK
                     LHMEIDKEDCGETFYDVISQALSDRGE"
BASE COUNT         1044 a          374 c          539 g          941 t
ORIGIN      
        1 gaaaatattt atttgttaag ggaaaagaca cataagttat tttatagtga gtttgaaaat
       61 cagttatttg aaacgatcat gttcctttcg atgaaaacac tagttttaga tataaatcat
      121 ttttccaagg aaattgaaaa taagtcagag gcatatgagc agtgtataca gcagataaga
      181 gaagaaaacg gaataaatca tttttttgac aggtatccgt atttgctaaa acaaattaat
      241 aaagaagtag gactgataga ggaatcatat tctttattat ttgatagatt tttagaagac
      301 ttatctgaga taaggtcgtg ctttaacatt agtgagcccc taagcaatgt tgccttttca
      361 cttggtgaca gtcactctaa aaagcaaaca gttgttaaaa ttgcgtttaa agagaaatct
      421 gtttactaca agcctaaaag ttatcattca cacagtatct tgttagaact tactagttta
      481 ttgaaatcta gtaatatacc ttcattcagt cttcctaaaa gcttagttaa agcagattat
      541 tgttggcaac ttggtgtagc ttatacaagt tccaataaag atgaagtagc gaaaatttac
      601 tttaagtatg gtgttttagc agcattttct gaaatatttt ctattacgga cttacatatg
      661 gaaaatgtga ttgtttcagg cggagattta tatttaattg acgttgaaac attttttcaa
      721 agaaagttga atgtacaaaa tcagaatttt gaagggatta ctgtagacac ctatcagaga
      781 atttatgaga catcactttc aaacggttta tttcctgtac aatttgagaa aaacagcgct
      841 cctaacgttt ctggaataag tggaaaaggt ggaaaaagaa aaaaaggaaa atatgaactg
      901 ataaataaaa atcgtggaga tatgaagtta gtaaaagttg actattttca agaagatggg
      961 ttcaatattc ccacattaaa tgggaaagtg gtagagcctc ttgactatgc taatgagatc
     1021 atttcaggat ttagagagtg ctacatattt cttctatcac aacgttcaaa gattaaagga
     1081 atagtagaag gttttccaga attgaaaagc agagccctat ttcgaaatac ttccgattat
     1141 ggaaaatttt tgcaagcttc tacgaatcca aagtatcttt tctcagaaaa aaagaagaag
     1201 aatttatttt cgatactata tgaggcaaaa catattgaac attttattgt tgataatgaa
     1261 attaaagatt tgatgaatgg tgatattcct tacttttcaa tggataccag aggaaacgtc
     1321 tataattctg tagggacatt aattggaaat ctaggagata caacctcgtt atttgatagt
     1381 ataactattt tgaacgatga aagattgaag ttcacttgtg aattgcttga aatagtcttg
     1441 aaaaaaccga ttaagcattg ggagagggaa aagggcaaat cttatcagtt tttatcaatc
     1501 tcctcagaac attaccttct ctaaaattga taaaactgat tttaggaata tatcggcttt
     1561 tgtatctcaa gattctccca tgtttgatgg ggatgtgatg tataacattt cgctagggag
     1621 agaatctgtt tcaggagaac aggttattga aacttgtaaa agggtatcaa tatatgatga
     1681 tatcaggagt atgccaatga agtttcatac cccacttttt cgagataatc catcactatc
     1741 tggggggcaa aaacaacgaa tttctttagc aagagaactt gtaaccaccc ctagaatctt
     1801 agttcttgac gaacctacat cagctttaga tgtaaaaact gaaagaataa tccaaaaaaa
     1861 tgttgaggct ttacattgta cgaggatttt ggttacccat agacttaata cagttgaaaa
     1921 agctgataag attttaataa tggataatgg caaaattatt gactatggaa accatcatta
     1981 tttgtacaaa aataataagg attattgtga cttatatgac tcgtatatga ataaatatca
     2041 ggaggaagag gtaaaatgaa acaattagta ttaaaagatg tttgcaaaaa atatcccaat
     2101 caactgaatt atgctctaga ccatatcaat ttgattgtgg aaaaaggaga atttgtagct
     2161 gtcatggggc gtagtggtag tggaaaaaca acacttttaa atgttacttc aattattgat
     2221 aaaattgata gtgggagtat ttattgtgca gacaaagaaa ttagtgcatt ttctgataac
     2281 gaggcaacta gttttagaaa aaatgatatt ggttttgttt ttcaagatta tatgctgtta
     2341 gacagtctaa ccattaggga gaatatttct gttgctctat ctttaaaaaa tgttgattca
     2401 tcaaaaattg atgatttgat aaataactat gcaaaaagat ttaatttata tgagcagttg
     2461 aaaaaatatc cgtatcaact ttctggaggt caaagacaga gggtcagtat tatcagagca
     2521 atcattaaag aaccagagat tatttttgct gacgaaccaa ctggagcgct tgacttaaaa
     2581 tcttctgaag gaacaatgag gattttgagt gaaatcaata aaatagaaaa ggtaactatt
     2641 ttaatggtta ctcatgacgt tttatcagct tcttatgcgg atagagttgt acttctcaaa
     2701 gatggtaaac ttcacatgga gattgataaa gaggattgtg gagagacgtt ttatgatgta
     2761 attagtcaag ccttatccga tagaggagag taatatgatt tggtccatta caaaatctaa
     2821 catcaaaaaa aacttttcgt tatatcgtat ctattttcta gctacgattg gtttattaag
     2881 tatttttata gcttttct
//
LOCUS       DATWVB010000082         2802 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.082, whole genome shotgun sequence.
ACCESSION   DATWVB010000082 DATWVB010000000
VERSION     DATWVB010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2802
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.082"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(696..896)
                     /locus_tag="VCX65_001719"
     CDS             complement(696..896)
                     /locus_tag="VCX65_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEP5054155.1"
                     /translation="MTTMKELTINDMASISGGNAPGDAVIGGLGGLASGLKFCKLPHP
                     VLAGGCVVGFTVGGAYLGYTAN"
     gene            complement(909..1136)
                     /locus_tag="VCX65_001720"
     CDS             complement(909..1136)
                     /locus_tag="VCX65_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEP5054156.1"
                     /translation="MEIKKLETFHQMTIEKLAKVEGGKNNWQANVSGVIAAGSAGAAI
                     GFPVCGVACGYIGAKTAITLWAGVTGATGGF"
     gene            1455..2140
                     /locus_tag="VCX65_001721"
                     /pseudo
     CDS             1455..2140
                     /locus_tag="VCX65_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2331..2513)
                     /locus_tag="VCX65_001722"
     CDS             complement(2331..2513)
                     /locus_tag="VCX65_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEP5054157.1"
                     /translation="MDNFLELQFEELVNISGGKGNIGSAIGGCLGGMLIAAAGGPITG
                     GAAAFVCVASGIAAYQ"
     gene            complement(2528..2761)
                     /locus_tag="VCX65_001723"
     CDS             complement(2528..2761)
                     /locus_tag="VCX65_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEP5054158.1"
                     /translation="MIKFAEEIQKEELFHIIGGYSATDCKNHLIGGITSGAIAGGVGA
                     GMATLGVGGVAGAFAGAIAGGLTCVGGMLFNGK"
BASE COUNT          927 a          599 c          383 g          893 t
ORIGIN      
        1 gtacagcagc ccaaatagga taagggtgcc taaagttgta ggctacactc aagatgataa
       61 gggtaaaagg gacaatgtaa cctcccagct tttcaacatt ttctagaaat atcatctttc
      121 tatcatatag gttaaaaata atatctaaaa ttttcatacc actcctctac tacttatata
      181 tcagtgatag atagtcattt atatatttag tgaggccaga taatatttgt agcagcacca
      241 gctgctccac acaaaatata accttgccaa gggataaata cgcctgtctg agcacaaact
      301 gtcactccct gcgcagcacc tgccatccct gtcaaaaaga tatttgctcc gtcttttccg
      361 cctccattta tgatagtcag accatttttt tagcacttcc atatttttga agtctttttc
      421 attctaattt cactcttttg tattttaaaa agctaagagt gatatctaaa ttcattggca
      481 taatcactat tttcttttat cgataaaaac aaataatgac gctaccaaag ctacgataga
      541 taacatgttt accgattttt ccgaaaggga taattgattg aaaattaaaa acactaaata
      601 tggtatagat ttatcaacat ttttttatga atggcatcaa caatgattaa aaacattata
      661 gacgcattca taataataaa aatcgtatag atcatttaat ttgctgtata tcccaaatat
      721 gctccaccaa ctgtaaatcc tacaacacat ccacctgcca atactggatg tggcagttta
      781 caaaatttca atccagaagc taagcctcca agaccaccaa ttacagcatc tcctggagcg
      841 tttcctccac ttatactagc catgtcatta attgttaatt ccttcattgt tgtcatcctt
      901 tctttcctct agaagccgcc tgtagctcct gttacaccag cccaaagagt aatagctgtt
      961 ttagctccaa tataaccaca ggctacaccg caaactggaa aacctatagc agctccagca
     1021 ctacctgcag cgataacccc actgacattt gcctgccaat tattcttacc accctcaacc
     1081 ttggcaagct tttctatagt catttggtga aatgtttcca gtttctttat ctccatatcg
     1141 aataacttct tttcataatt cttaaatttg tctcgttgca acctcgagct agtacagaat
     1201 atcataaaga acagtatcat ggtttcaaaa tcttaaaagg ctatttttca tcatgaaatg
     1261 tctttttatc ctctctacac ttacgctgtg acaatagtta attaattaag aagtttaaat
     1321 gataccattc atgcttttat aaataccttt taagattttt gatggtagtg taaaatatct
     1381 tgtgtaaaca cacaaaaagg aataaatctt gtatagtaga gttacgacac ttcactagaa
     1441 agagatttat tcccatgact cagtttacca cagaattact taacttccta gcacaaaaac
     1501 aagatattga tgaattcttt cgctcctctt tagaaatagc tatgaatgac ctcttgcaag
     1561 ttgaactatc agcttttctt ggttatgaac cttatgaaaa agaaggttac aacacaggta
     1621 atagccgtaa tgggacttat tctcgtcagt ttgaaacaaa gtatggctta gtcaatttaa
     1681 tcatcccaag agatcgaaac ggcgagtttt caccagtttt attaccatct tatgctagac
     1741 gagatgacca cttggaagag atggtgatca aactctatca gactggcgtt acgacacgcg
     1801 aaatcagtga cattattgag cgcatgtatg gtcaccactt gtttctgaat ggaagcctcg
     1861 ttataaaaag gtcatggcat cacttgaaac gacggaaaat ctccttactt tctatcaatt
     1921 cccacatcac atttggtcta gcatttactc tacaaacttg attgaatcac tcaataaaga
     1981 aattaagcga caaaacaaga agagagtggt tttcccaaat gaagaagcct tagaacgatg
     2041 tcttgtaagt attttcgagg actataatat taagttcgga gctcgtattc ataaaggatt
     2101 cggagtatgt tttgacacac ttgatagctt atttgactaa tattcaaaaa ctctactctt
     2161 gtgtttacac aacattttaa tattattaat ttgtaatagt acttagtaag acataaacaa
     2221 atatcacaat taaaattact ttacttgcat tttctcttac ctctttatcc ttcaaaaaaa
     2281 tttgggaaag tattagacaa attaaaccga gtattataac tataatcata tcattgataa
     2341 gctgcaattc cagatgctac acatacaaat gctgccgcac ctccagttat tggacctcct
     2401 gctgcagcta taagcatccc acctaagcac cctccgatag cagatccaat atttcctttt
     2461 ccaccagaaa tatttactaa ttcttcaaac tgtaattcta aaaaattatc catttttcac
     2521 ctcaaaatta ttttccatta aataacatac caccaacgca agttaatcca cccgcaatag
     2581 cacctgcaaa cgcacctgca actcctccaa cacctaaagt agccatacct gctccaacac
     2641 cacctgcaat agcacctgaa gtaataccac caattaaatg atttttacaa tctgtagcac
     2701 tataacctcc aataatatgg aacaactctt ctttttgtat ttcttctgca aattttatca
     2761 taactttaaa aacctttcta aaatgttata ttcatcttgt tg
//
LOCUS       DATWVB010000083         2767 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.083, whole genome shotgun sequence.
ACCESSION   DATWVB010000083 DATWVB010000000
VERSION     DATWVB010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2767
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.083"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..309)
                     /locus_tag="VCX65_001724"
     CDS             complement(<1..309)
                     /locus_tag="VCX65_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5054159.1"
                     /translation="MKSYLCSNFLKIKNTSYLLIHILAALLFPLLLFFYWSQRGGLQS
                     RTVLFSYFQIVGVLLPFVASIVCIQLKNLEESSGKYKYLLGYSQSNYKPFIVELVFLW
                     L"
     gene            complement(312..1061)
                     /locus_tag="VCX65_001725"
     CDS             complement(312..1061)
                     /locus_tag="VCX65_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HEP5054160.1"
                     /translation="MVQIFLSNLFKIKNTSISKLILIFPIICVMLSLLFSALGGESIL
                     RLAAETTVNQWGVIWINVIIAVNSGLLNKLELDSNKYSVFLSRDVDLKKVEYARVLLI
                     ALINLIISMILSLMLIVISFVLPTPSLISIGRILLTILLIWLTTLWQIPFILWLSRKI
                     NVYFAMIINIISPLIIGTSFSLLNKWYLFPYDWSLKLLEPMTRMRINSIPFGAEFVPD
                     YSQIFISLFLGIAFFILLTNLFAISFKKQVK"
     gene            complement(1067..1756)
                     /locus_tag="VCX65_001726"
     CDS             complement(1067..1756)
                     /locus_tag="VCX65_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HEP5054161.1"
                     /translation="MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIM
                     KILTGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVS
                     ESAILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIG
                     IQELREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYEGKIVLEKEYDGSENLEEL
                     FNNQILFEKRR"
     gene            complement(1762..>2767)
                     /locus_tag="VCX65_001727"
     CDS             complement(1762..>2767)
                     /locus_tag="VCX65_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HEP5054162.1"
                     /translation="EILFKNINKYRFVSLRGIEQGESIFKDNLGNYNTEIVVPILKES
                     NGINNTNDNVQFKNEVKKIYLPFCDWLFFKFYGPKERQEELLNNWKKFWLNLPSELFS
                     QSNMFYMRYNDTNDHIRIRINCDSIENNFSLYLSVVQDLLPQLIESCIISDIEVSSYK
                     PEVNRYGGPHLISYAEEIFCKESILFLNNTIEFSDDERLVCATYLVLYYLNHFFKDKE
                     TRRSFLFENYTGKYKKDFKNLPIDLPIEYMKILNGVTSALDRYDFFQEMDRYLMSYMK
                     EYNRFGGTNDIYNTKFNLVGSFLHLSMNRLNGIDREFEEKVYCFAYYTLNAQQYIEWE
                     "
BASE COUNT          996 a          475 c          336 g          960 t
ORIGIN      
        1 taaccataga aatactaatt ctacaataaa tggcttataa ttcgactgtg agtaacccaa
       61 taaatattta tattttccag atgattcttc caaatttttt agttgaatgc acacaatact
      121 tgcaacaaaa ggaagaagta cacctactat ttgaaagtag gaaaataata cagtcctgct
      181 ttgtaaacct ccacgttgac tccaatagaa aaatagaagt aagggaaata atagtgcagc
      241 taaaatatgt attagtaaat atgaagtatt tttgattttt aaaaaattag aacataaata
      301 tgatttcatg actatttcac ctgttttttg aaagagatag caaatagatt ggtcagtaag
      361 atgaaaaaag caattcctag gaacaatgat ataaaaatct gtgagtagtc tggaacaaac
      421 tccgctccaa aaggtatact atttattctc attcttgtca ttggctcaag caacttcaac
      481 gaccaatcat aagggaacaa ataccattta tttaagagag aaaaacttgt accaataatt
      541 agtggagata taatattaat aatcatagca aaatacacat taatttttct tgatagccat
      601 aaaataaacg ggatttgcca tagtgtagtc aaccaaatta acaagatagt taatagtatc
      661 ctacctatac taataagact tggagtaggt aggacaaaac taatcacaat aagcattaag
      721 cttaaaatca tactaattat tagatttata agagctatca atagaactct ggcatattct
      781 acctttttta aatcaacatc ccttgataaa aaaacagaat acttattaga atctaattct
      841 aatttattta acaaaccaga atttacagca ataataacat taatccaaat aactccccac
      901 tgatttactg ttgtttccgc agctaaacgt aggatacttt caccacctaa tgctgaaaac
      961 aataaagata acatcacaca aataatagga aaaataagaa tcaacttgct aatactcgta
     1021 ttttttattt taaataaatt tgataaaaaa atttgtacca tagcccctac ctcctctttt
     1081 caaataaaat ttgattattg aataactctt caagattctc agagccgtca tattcttttt
     1141 ccagaacaat ctttccttca tagataaatc caataaaatc agctagatgt tcaacttctg
     1201 acagtatatg gcttgaaatc ataattgtca ttccttctga tttaaatgac tctataattt
     1261 cccttaattc ttgaattcca attgggtcca agccattagt aggttcgtct aatataagta
     1321 atttaggtga atttattaaa gagatagcta tacctaaccg ttgcttcatt ccaagagaaa
     1381 attgttttac tggtctcttg tcaatatttc ctagaccaac tttatttaat aatggaagta
     1441 tagcgctttc tgaaacacca agcattgttg taactacctt catattatcg taagcactca
     1501 aatttttata aagtggtggt tcttcaataa tactcccgat ttttcgcaga tcccgacgtg
     1561 accattctct accttcaaaa ataatagaac cacttgtctt actaactaag cctgtcaaaa
     1621 ttttcataat agttgatttt ccagcaccat ttggaccgat taaagcatac acttttccct
     1681 taggaatatt catattgaca ttattcaata tggttctctt accataagat ttttttagat
     1741 tttgtatttt caacatatta gttactccca ttctatatat tgctgagcgt ttagtgtata
     1801 gtaagcaaaa caatacactt tctcttcaaa ctctctatca atcccgttta atcgattcat
     1861 tgatagatgt aaaaaacttc ctactaaatt gaatttagta ttatagatat catttgtacc
     1921 accaaatcga ttatactctt tcatataaga catgagatat ctatccattt cttggaaaaa
     1981 atcatatcta tcaagagctg aggtgactcc attcaaaatc ttcatatact caataggtaa
     2041 atcaattggc aaatttttga aatctttctt atactttccg gtataattct caaataagaa
     2101 agagcgcctt gtttctttat ctttgaaaaa gtgatttaga taatatagaa ccaagtaagt
     2161 agcacaaact aatctttcat catctgaaaa ttctattgta ttattaagaa ataagataga
     2221 ttctttacaa aaaatttcct ctgcataact tattaaatga ggtcctccat atctatttac
     2281 ttctggttta tagctactca cttctatgtc agagataata caactctcaa tcagttgagg
     2341 taatagatct tgaactactg acaaatacaa agaaaagtta ttttcaatcg aatcacaatt
     2401 tattcgaatt cttatatgat cattggtatc attatatctc atataaaaca tgttactttg
     2461 gctaaacagt tctgatggca ggtttagcca aaattttttc cagttattta gtaattcttc
     2521 ttgtcgctct tttggaccat aaaatttgaa aaatagccag tcacaaaatg gtaaatatat
     2581 tttcttaact tcatttttaa attgaacatt atcgtttgta ttgtttattc cattagattc
     2641 cttaagaatt ggaactacta tctctgtatt gtagttccct aaattatcct taaaaataga
     2701 ctctccctgc tcaattcctc tcaaagaaac aaacctatat ttattaatgt ttttaaataa
     2761 aatctct
//
LOCUS       DATWVB010000084         2545 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.084, whole genome shotgun sequence.
ACCESSION   DATWVB010000084 DATWVB010000000
VERSION     DATWVB010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2545
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.084"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            59..472
                     /gene="yaaA"
                     /locus_tag="VCX65_001728"
     CDS             59..472
                     /gene="yaaA"
                     /locus_tag="VCX65_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEP5054163.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRIGDKISLPDQDLIITIVEPSQEEKEQFAEEIAEKTRVAALVKQMNQANKK
                     TSSKHKNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            474..1580
                     /gene="recF"
                     /locus_tag="VCX65_001729"
     CDS             474..1580
                     /gene="recF"
                     /locus_tag="VCX65_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEP5054164.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLAGYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDNLAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQVDSDIH"
     gene            complement(1637..2500)
                     /locus_tag="VCX65_001730"
     CDS             complement(1637..2500)
                     /locus_tag="VCX65_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEP5054165.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWLFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIIGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
BASE COUNT          898 a          495 c          422 g          730 t
ORIGIN      
        1 attattattt atttctgttt tatgctataa tgacttgaat gacaaaatgg agatgacaat
       61 gatatacaaa ttatttacag aatttatcac cctacaagcc cttcttaaag aattaggaat
      121 tatccaaagt ggtggcgcta tcaagggatt tctcgctgaa acaaccgttc tatttaatgg
      181 tgaagatgag aaacgtcgag gcaaaaaaat cagaataggg gataagattt ctctacctga
      241 ccaagactta attatcacta ttgttgagcc tagtcaagaa gaaaaagaac aatttgccga
      301 agaaatagct gaaaagacac gtgtagcggc tctagtgaaa caaatgaacc aagctaacaa
      361 aaagacttct tctaaacata aaaatcgtca atctactacc aaaaaatcac taagagcaac
      421 taagaaaact aaaggtaaac caactgcacc tgtccgcttc ccaggtatct agtatgtgga
      481 ttaaagagtt agagttaaaa cattatcgca attatgacca cctgcttgcc tcattttcgt
      541 cgggtttaaa tgtctttatc ggtaataatg ctcaaggaaa aaccaatttt ctcgaggcaa
      601 tctattttct atcacttact agaagtcatc gcacgagggc tgataaagaa ttgattcatt
      661 ttgatcactc aactgtttct cttactggta agattcagcg tattagtggt actgttgatt
      721 tagaaatcaa tctatcagat aaaggacgtg tgacaaagat taatgcgcta aagcaagcaa
      781 aattatctga ttatattgga acgatgatgg ttgtgctttt tgcaccagaa gatttgcaac
      841 tagttaaggg agcacctagc cttcgtcgca aatttatcga cattgacctt ggtcaaatta
      901 agcctgttta cttatctgag ttatcccatt ataaccacgt gcttaaacag cgtaatagct
      961 atttaaaaag tgcccaacaa attgatgccg cttttctagc tgttctagat gagcaattag
     1021 ctggctatgg agcccgtgtc atggaacatc gtattgattt tatcaatgcg ttagagaaag
     1081 aagcaaatac tcatcaccaa gccatctcaa atggtttaga aagtctctct ctctcctatc
     1141 agtcgtcagt tgtctttgac aaaaaaacta atatttacca acaattttta caccaacttg
     1201 aaaaaaatca tcagaaagat ttcttccgta aaaacactag cgttggtcca catcgcgata
     1261 acttagcctt ttacattaac gggatgaatg ctaactttgc tagtcaaggt cagcaccgca
     1321 gccttattct ttccttaaaa atggctgaag ttagtttaat gaaggccttg actggagata
     1381 accccattct tttactagac gatgtcatga gcgagctaga caatacacga caaacaaagt
     1441 tacttgaaac agtaattaaa gaaaatgtcc aaacctttat cacaacaaca agtttggatc
     1501 acctgtcaca gttgccagaa ggtatccgta tttttcacgt aacaaaagga accgttcaag
     1561 ttgattctga tattcactaa taacatcaaa aaaagggttc agttaaactg agcctttttt
     1621 tgatattatg tggcgattaa gatttgacca cacctaataa aatagcacct acgataaaac
     1681 aaataattcc tgtgacaacc caacgcattt cttttttggt tttggtttcg cctaggaata
     1741 aaatgcctcc aacaatcgaa atgatagcac ctaattgtga gaaactaaag gcaatagcaa
     1801 gtcctgcttt tgatgcagct aaaagcatga aaatattccc aatgccccaa agtaatccaa
     1861 caacgctatt tttaatcaca tactggtcaa tggaaatttt aaatgacatg aaagttatag
     1921 ctcctaaaac catacctact gccatgggca aaatgactga caaaacttca aatttcatga
     1981 tgttattaaa taatacagca tacatcacgt aaccaattgt tgaataagtg agcgccctaa
     2041 atccttttga aaaattatga aggtgattga cttgtgcatt agcatcatct tgtttactag
     2101 aaaagtaaaa accaataatc agaagtaata gtgctagact tcctactaca aattgcatag
     2161 gtcttgtcca ttcatgaaaa acgaggacac caatcaaact tcccagaaca agttgagagc
     2221 cacttgacaa aggattggca acggagactc ccatgtattg catggcatga aattgaccag
     2281 tttgaccaat tgaccagata aaaccaccca atattccaaa aagccaaagt tgcagtgtca
     2341 tctcaggtct aacaattaac caaacagcta atgaaaataa taaagcccca aaagtcattc
     2401 ctagagtttg ttgcgaaggt tttcctccaa ttttgttact aacaaatcca atgcttcccc
     2461 atgtaaacat gggaataagt gcataaaaaa taccttccaa aatgttatct cctttatagt
     2521 aaatctttaa agattataat aattc
//
LOCUS       DATWVB010000085         2467 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.085, whole genome shotgun sequence.
ACCESSION   DATWVB010000085 DATWVB010000000
VERSION     DATWVB010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2467
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.085"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            154..888
                     /locus_tag="VCX65_001731"
     CDS             154..888
                     /locus_tag="VCX65_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEP5054166.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSGFFIEDNDVLCIA
                     SKVVSIAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIKGLDYKWSENTSIKEALNE"
     gene            881..1867
                     /locus_tag="VCX65_001732"
     CDS             881..1867
                     /locus_tag="VCX65_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEP5054167.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKMFASEQYFFSKILEKLLQVDCFSLDKIKEITVNFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKHDYSIEILS
                     CINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTIDDKTILFDPHPKLERYKSELVT
                     GTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEITKLLINLYSECEKIYL"
     gene            1877..>2467
                     /locus_tag="VCX65_001733"
     CDS             1877..>2467
                     /locus_tag="VCX65_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEP5054168.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKAN
                     DTATMISYWPLTISEELALMIEGYFYKLDKNELPTPR"
BASE COUNT          921 a          301 c          479 g          766 t
ORIGIN      
        1 ttatcgatta taaaacaatc attcatgaaa tccatgaaca ttttatagac ttaattttta
       61 gtttagaagt acatgaaaaa gaaatagaca aaaaggcaga agtagtgagg aagtcttatc
      121 tgacactaaa tgagtatatt aatggaggct aaaatgaatt tgagtatatt tggtttaaag
      181 aatattcctt atttgaaaga aggggatagt atagaaaagc ttattgaaga aagcattaaa
      241 acttcaggat tttttatcga agacaatgat gtgctttgca tagcttctaa agttgtatct
      301 atcgcagaag gccaggtgat gtctttaaac gagatacaag tgagtgatgt agcaaaagaa
      361 atccacagga atattcctcg taaagatcct agaataattg aaattatgct aaatttagtc
      421 aatagagatc tgtcacgttt agatatcaaa aaaaattaca ttggttgtcg cttggaaaat
      481 ggtttaaagt tgacaagtgg tggaatcgat agaaaatcag tagatgaagt atttctttta
      541 cctaataatc cggatgcttc tgcaaaaaga atttcggaat atcttaaaaa atcacttgga
      601 aaaaatgttg cagttgttat aacagatagt gatggtagag aggataaaag aggtgctact
      661 caagtagcaa ttggtattta tggtattcat cctttgagaa aaacagaagt aatagattca
      721 caaggagaga caataaaatt ccaagaagag actttgtgtg atatgattgc agcttgtgct
      781 ggcttagtaa tggggcaacg tggaactgga attccagctg tcctcattaa gggcttggat
      841 tataaatggt ctgaaaatac tagtattaag gaagcgttaa atgagtagaa atcaggactg
      901 taagaatatt ctaatcattg gttttggaaa aattgggaaa attaaagcgt acaagtggct
      961 atcacgcgga tatgaggtat atgtcaaaga tttgaaattc tccagcatga aataccttaa
     1021 tacaaatagt gatgtgttgg atgatttatc acgacaatat tttactattg agatttgtac
     1081 tccgacaaat caccacctta cgctattgaa aaccgttata acaaggtatg tctattctta
     1141 tattagcatt gaaaaaccac tgtgtaacag gttagaagat ttagaagaaa tgaagtcgct
     1201 agtagaaagt cacccacatc tagcaaaaaa aatgtttgcc agtgaacaat acttcttttc
     1261 gaaaattttg gaaaaactgt tacaagtaga ttgtttctct ctagataaaa tcaaggaaat
     1321 aacagttaat ttttctaaag ataggattga ggataacgag aatgggagat ttttagataa
     1381 agagatattg ggctatggaa tagagattcc tcatatcatt gctgtcattt cttatttagg
     1441 aatttcatta gaagaattca aaaaagggat ctttgtgaat gctatttata taaaagactt
     1501 agagaaacac gattattcaa tagaaatatt atcttgtatt aatcaaacag tgattaaaat
     1561 tattagtaat ttgggaagtt ttgcaataag agagggcaag attgaaggag gtgatgctaa
     1621 aacagtaaga agagttacca ttgatgacaa aacaatacta tttgatccac atcctaaact
     1681 cgagaggtat aagagtgaat tggtgactgg gacaaatacg tttcaaatac acgatgatat
     1741 gatggacacg tatatcagtt tgttagaagg aaatgctatt cctgaagatt gctatatcaa
     1801 taatgcaatt gagataacaa aattattaat taacttatat tcagaatgtg aaaaaattta
     1861 tttatgaggt gtaactatgg atttaaaaat tacaaacggc ttttatgacc caagtcattt
     1921 atcatacgaa gtagtagaac gtaaaggatt agggcatcct gataccttag cagatggaat
     1981 tgctgagcaa attgaaattg attactcact ttattgtttg gacaagtttg gtgttattcc
     2041 acatcataat tttgataaga ttattatccg agggggacat tcagttcagg attttggtgg
     2101 aagtgacttt attgaaccaa ttaaaattat ttttctaggt agggcgagca aaaaatgttt
     2161 taatagttca attccacttt ttaaaattca gaaaaaggct gcaactaaat atttaaatag
     2221 aattttacct aatttagatg ttgaaaatta tgtagaattt gagacattga cctcagattt
     2281 tactacaaaa actaattggt tctcgcctga agcaatagaa gatttaccgg agtatctaga
     2341 tgtaccaaag gcaaatgata cagctacaat gataagttat tggccattaa caatttctga
     2401 agaattagca ttaatgattg aagggtattt ttataaatta gataagaatg aattaccaac
     2461 gccaaga
//
LOCUS       DATWVB010000086         2426 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.086, whole genome shotgun sequence.
ACCESSION   DATWVB010000086 DATWVB010000000
VERSION     DATWVB010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2426
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.086"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..499
                     /locus_tag="VCX65_001734"
     CDS             <1..499
                     /locus_tag="VCX65_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054169.1"
                     /translation="IDWENVSDDIEPLKIHRNFYESISEKTDSEVIEEIKNLEDINFT
                     DEKGNDLDDLTIIVPAQDEGFKRVFLGQREWYDIRIGKSKRNRIKYIAGYEVAPESGV
                     KYWAEVDKIVPSDNYVGYWKVIFKGEVKEYSEYKRLGNTWPPQNSRYVSKKALDEAKY
                     LSDVF"
     gene            519..1811
                     /gene="purB"
                     /locus_tag="VCX65_001735"
     CDS             519..1811
                     /gene="purB"
                     /locus_tag="VCX65_001735"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEP5054170.1"
                     /translation="MIERYSRPEMAAIWTEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDTKVTSCLTQEELDELFNPIYYTKRVDDIFKRLGI"
     gene            1942..>2426
                     /gene="rgg4"
                     /locus_tag="VCX65_001736"
     CDS             1942..>2426
                     /gene="rgg4"
                     /locus_tag="VCX65_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Rgg4/ComR"
                     /protein_id="HEP5054171.1"
                     /translation="MLEHFGGKVKVLRLEKRISHEDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
                     L"
BASE COUNT          799 a          390 c          548 g          689 t
ORIGIN      
        1 aattgattgg gaaaacgttt ctgatgacat agagccctta aagatacatc gtaactttta
       61 tgaatcaatt agtgaaaaaa cagattctga agttatagaa gaaatcaaaa atttagaaga
      121 tataaatttc actgatgaaa agggtaatga tttggatgac ttaaccatta ttgttcctgc
      181 gcaagacgaa ggatttaaaa gagtctttct aggtcaacga gaatggtatg atatacggat
      241 aggaaaatcg aaaaggaata ggattaaata tatcgcagga tatgaagttg caccagagag
      301 tggtgtaaag tactgggctg aagtggataa aatagttcct tcagataact atgttggtta
      361 ctggaaagta atttttaaag gagaggtgaa ggaatattca gaatataaaa gattaggaaa
      421 tacttggccc cctcaaaaca gtagatacgt atctaaaaag gctttagatg aagctaaata
      481 tttatcggat gttttttaat taaaggagaa aaaacaaaat gatcgaacgt tattcacgcc
      541 ctgagatggc ggcaatttgg acagaggaaa ataaataccg tgcttggttg gaggttgaga
      601 ttctggctga cgaggcatgg gcagagttgg gtgagattcc taaggaggat gtggctaaga
      661 ttcgtgagaa ggcggatttt gacattgacc gcattcttga gattgagcag gagacgcgtc
      721 acgatgtggt ggctttcacg cgtgcggttt ctgaaacgct tggtgaggag cgcaagtggg
      781 tgcactacgg tttgacctcg actgacgtgg tggacactgc ctacggttac ctctacaagc
      841 aagctaacga cattatccgt cgcgatcttg agaatttcac caatatcgtg gcagacaagg
      901 cgcgtgagca caaaatgacc atcatgatgg gtcgtaccca cggtgttcac gccgagccaa
      961 cgactttcgg tcttaagttg gcgacttggt acagcgagat gaaacgtaat attgagcgtt
     1021 ttgaacatgc tgctgcaggt gtggaagctg gtaagatttc aggtgccgtt ggtaactttg
     1081 ccaacatccc accttttgtg gaagaatatg tctgtgacaa attaggcatt cgtccgcaag
     1141 aaatttcaac acaagttctt ccacgtgacc ttcacgcaga atactttgca gtgcttgcaa
     1201 gtattgcaac ttctatcgaa cgtatggcga cagagattcg tggtctgcaa aaatcagaac
     1261 aacgtgaagt tgaagagttc tttgccaaag gtcagaaagg tagctctgct atgcctcaca
     1321 aacgcaaccc aatcggttca gagaacatga cagggctagc gcgcgtgatt cgtggtcaca
     1381 tggtgacagc ttatgagaac gtgtcacttt ggcatgagcg tgatatttca cactcatcag
     1441 ctgagcgtat catcacacct gacacaacta tcttgattga ctacatgctc aaccgctttg
     1501 gcaatatcgt taagaacttg actgtcttcc cggaaaatat gatgcgcaat atggaatcaa
     1561 cttttggttt aatttatagt caacgtgtta tgctcaaatt gattgaaaaa ggaatgacac
     1621 gagaagaagc ttatgactta gttcaaccta agacagctta ttcctgggac aatcaagtgg
     1681 atttcaaacc acttttagaa gaagacacca aagttacctc ttgtcttaca caagaagaac
     1741 ttgatgaact atttaatccg atttattaca caaaacgtgt tgatgatatt tttaagcgtt
     1801 tagggattta atataaaaaa aagaaggtga ttcccttctt ttttatttaa aaaacgaata
     1861 ttttctttaa aaatattaaa aatgttagtt tttaattaga cgctgtgata taataaagaa
     1921 aacagttgtt ggagagaaac catgttagaa cattttggtg gaaaagtaaa agtgttaaga
     1981 cttgaaaaga ggattagtca cgaggacttg tgtggggatg agtctgaact ttctgttcgt
     2041 caattagcac ggatagaact aggtcaatcc ataccaagtt taagtaaggt tatttttatt
     2101 gcaaaagcct taaacgttag tgtcggttac ttaactgatg gtgctgattt agaactacct
     2161 aagcgttaca aagaattaaa ataccttatc ttaaggacac caacttacat ggatgatgga
     2221 aaattacaag tacgagaaga gcagtttgat gaaatttttg aggattatta tgataaatta
     2281 ccagaggaag agaaaataat cattgattgt ttacaggcaa ctttagatac tttattgagt
     2341 gagaatacta actttggcat tgacttactt caagaatatt ttaatcaaat aaagactaag
     2401 gtacgcttta ggcaaaatga tttaat
//
LOCUS       DATWVB010000087         2389 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.087, whole genome shotgun sequence.
ACCESSION   DATWVB010000087 DATWVB010000000
VERSION     DATWVB010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2389
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.087"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..185
                     /locus_tag="VCX65_001737"
     CDS             <1..185
                     /locus_tag="VCX65_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP5054172.1"
                     /translation="TDEEKKKIFDRFYRVDKARTRQTGGFGLGLALAQQIVMSLKGNI
                     TVKDNDPKGSIFEVKL"
     gene            complement(310..558)
                     /locus_tag="VCX65_001738"
     CDS             complement(310..558)
                     /locus_tag="VCX65_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEP5054173.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(612..1532)
                     /locus_tag="VCX65_001739"
     CDS             complement(612..1532)
                     /locus_tag="VCX65_001739"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEP5054174.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            1767..>2389
                     /locus_tag="VCX65_001740"
     CDS             1767..>2389
                     /locus_tag="VCX65_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP5054175.1"
                     /translation="MKKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLETLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEILRKDKGYYVLRSIKQT"
BASE COUNT          807 a          333 c          441 g          808 t
ORIGIN      
        1 taacagatga agaaaagaaa aagatttttg atcgttttta tcgagttgac aaagctagaa
       61 cacggcaaac aggtggattt ggcttggggt tggctttagc tcagcaaatc gtgatgtctt
      121 taaaaggaaa tattacagta aaggataatg atcctaaagg tagtattttt gaagtcaaat
      181 tataagctaa aaagggcgac caataaggtc agccctttta aagttatttt taactgtcaa
      241 cgctttattg tattttttga gtttttaccg tataaaaaaa ctccagctgg agttttcatt
      301 ggatatttat tagccaagtt ttgcagcaag gcgtgcttta tcgcggcttg ctttgttttt
      361 gtgaatcaaa ccttttgatt cagctttatc gatgcttgaa gaagcagcgc ggaaaagctc
      421 ttcagatggg ttagcttcaa atgctttgat agcagtacgc atagctgatt tttgtgctga
      481 gtttttttcg tttgctttaa cgttaagttc agcgcgttta atagctgatt taatatttgc
      541 caatgttttc acctccaaat taatctaact acattattat atagaaaata tatgcgtttg
      601 gcaacccttt atcacttttt gaggtaaatt tcatcaattt tatgatcagc acttttatgt
      661 aaaattaatt cagcacggtt acgtgtaggt tcaatgaatt tttcaagatt ttctaaatta
      721 acggttttcc aaacgttgcg cgcaaatgct atagcctcag atcgaggtaa ttgtgcatat
      781 tgggcataat aattatgagg gtcacgtttt gctaatttta aaatgcttag aaaccgttca
      841 atgtaccagg tttcgatgtg actgctgtct gcatcaatat aaatagaaaa atcaaagtaa
      901 tcactcatat ataaacgatt gttttgttga ttttgaaaaa cattaatacc ttcgacgata
      961 aggaagtcag ggttattaaa tgattgtttt tgatttggga taatatcgta aatatcatga
     1021 gaatagacgg gtgcaaaagc cgtttgacca tttttgatgg aatctagaaa atctaagaga
     1081 agttccatgt tataagattc tggaaatcct ttacgattta acagtccttg ttcaataaga
     1141 aactgattag gatataaaaa accatcagtc gttaccagtt cgacttgact attggggtgc
     1201 gttcgtgata ataaaagttg taaaagacga ctagttgttg atttaccaac agctactgaa
     1261 ccagaaattc caataataaa aggccttaat tgaatgtctt tttttagaaa aaggctttta
     1321 gaaaaagaaa gattttcttg cgcaattttg taaacctgga tcagattaat taatggaagg
     1381 tagatatcaa tgacatcgtt aatactgatg ttatcattta agctagtaat acttttaagt
     1441 tcctcttgtg tgagaagagc ttttgctttt tgatgtaatg ttttccaaga ctctctagaa
     1501 attttttcaa agttgataaa ttcatttgac atggtagctc ctaatcattt gacagtgctt
     1561 acattatacc attttagtta aaaaataaat aatttttcgt tagtatttac acgaaaatta
     1621 atacgattaa ctcaaaaaag ccacacattc ctagtacaat tatcctgcta tattctaaca
     1681 aatagttaaa gttcggtttt tatttgtaat atagataaaa ttgttaaaaa acaagcgtct
     1741 tgtaaaccat ttcaaagtat gatagaatga aaaagtacct taaaaagata ggaaaaatga
     1801 tgacaaagat gtattatgat gaaaatccag atagtctaca cgatattcat gaagtaaaag
     1861 tagagctgct taatcatccc tttacttttt tgacggattc aggtgtcttt tcaaagaaaa
     1921 tggttgattt cggtagtcaa gtattattag agacactaaa tttcaaggag aacgaacgtg
     1981 tactggactt aggttgcggc tatggtcctc ttgggattag tctagccaag gttcaaaggg
     2041 tagacgcaac cttagtggac atcaataatc gtgctcttga tttagctaga aaaaatgcaa
     2101 ctaataacca agtggcagta actatttttc aatcaaatat ttatgaaaat attagtggcc
     2161 attttgagca tattattagt aatcctccta ttagagcagg aaagagagta gttcatagta
     2221 ttattgaaaa aagcatagat tttttagtgg ttaatggtga cttaacgatt gtgattcaaa
     2281 aaaaacaagg agctcctagc gctaaagcaa aaatggcaac tatttttggt aatgttgaga
     2341 tattaaggaa agataaaggt tattatgtat taagaagtat aaagcaaac
//
LOCUS       DATWVB010000088         2362 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.088, whole genome shotgun sequence.
ACCESSION   DATWVB010000088 DATWVB010000000
VERSION     DATWVB010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2362
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.088"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..203
                     /locus_tag="VCX65_001741"
     CDS             <1..203
                     /locus_tag="VCX65_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEP5054176.1"
                     /translation="VDFEKQNQQVVKLKKEYNELSKRTKKEKQLAERLKDDNFVKKYA
                     RAKYYLSREGEMIYPIPGLLPK"
     gene            338..1624
                     /locus_tag="VCX65_001742"
     CDS             338..1624
                     /locus_tag="VCX65_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEP5054177.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQLPSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFSFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            1621..>2362
                     /gene="tilS"
                     /locus_tag="VCX65_001743"
     CDS             1621..>2362
                     /gene="tilS"
                     /locus_tag="VCX65_001743"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEP5054178.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQSKSIQYF"
BASE COUNT          887 a          349 c          375 g          751 t
ORIGIN      
        1 atgttgattt tgaaaagcaa aatcaacagg tggttaaatt aaaaaaagag tataatgaat
       61 tgtcaaagag gacaaaaaaa gaaaaacaat tagcagaacg actaaaagat gataattttg
      121 tcaaaaaata tgctagggca aaatactatt tatcgcgtga aggagaaatg atttatccta
      181 ttccaggact attaccaaaa tgatgatgga taatattgta aaaaaaatag aagcatttct
      241 tgctttttct gataaaaaat tagcagagct gcaacaggaa aatcaaaaag ttaaagaaga
      301 aagtcagtat attcaaaaaa actagaaagg agtcaatatg agaaaattat tagcggctat
      361 gttaatgact ttttttctga ctcctttacc agtgattagt acagaaaaaa aacttatatt
      421 ttcaaaaaat gctgtttatc aattgaaaca agatgtcgtt caatcaacac aattctataa
      481 tcagctaccc tctaatccaa atctttatca agaaacgtgt gcctataaag acagtgattt
      541 aactctacca gcaggaagat taggtgtaaa tcaaccatta cttattaaat cgcttgttct
      601 taacaaagaa tctttaccgg tttttgagtt agctgatggt acctatgttg aggctaatcg
      661 acaattgatt tatgacgata ttgtacttaa tcaagtagat atagatagct atttttggac
      721 acaaaagaaa cttaggcttt attcagcccc ttatgtttta ggtacgcaaa caattccttc
      781 ttctttttca tttgctcaaa aagttcatgc cactcaaatg gcacaaacaa accatggaac
      841 ttattatctt attgatgata agggctgggc atcacaagaa gatctagttc aatttgataa
      901 ccgcatgtta aaagtccagg aaatgctctt acaaaaatat aataacccaa attattcaat
      961 ttttgtaaag caactcaaca cacaaacaag tgctggtatt aatgctgata aaaaaatgta
     1021 tgctgcaagt atctcgaagt tagcaccact ttatattgtt caaaaacaat tacaaaaaaa
     1081 gaaattagca gagaataaaa ctttgactta tactaaagat gttaatcatt tttatggaga
     1141 ctatgatcca ttgggaagtg gtaaaattag taaaatagct gataataaag attatcgtgt
     1201 tgaagaccta ctgaaagctg tagcacaaca atcggataat gtagcaacta atattttagg
     1261 ttattatcta tgtcatcagt atgataaagc tttccgctca gagataaaag ctttatcagg
     1321 tatcgattgg gatatggagc agcgcttatt aacttctcgt tcagctgcaa atatgatgga
     1381 agctatttat catcaaaaag gccaaattat ttcttacctt tcaaataccg aatttgatca
     1441 acaacgtatc acaaaaaata ttactgttcc agttgcacat aaaattggtg atgcttatga
     1501 ttataaacat gacgttgcta ttgtttacgg taatactcca tttattttgt ctatttttac
     1561 aaataaatca acctatgaag atattacggc tattgcagat gacgtttatg gtattttaaa
     1621 atgatgacct atcaagaaat ttttaatgaa ataaaaaata aagcctactt taaaaatcat
     1681 agacatgtgt taatagccgt atctggtgga gtagattcaa tgaatttatt gcacttttta
     1741 tacctgtttc aagacaaatt gaaaattcgt attggtattg ctcatgttaa tcacaaacaa
     1801 agatcagaat cagattcaga agaagcttat ttaaagtgtt gggctaaaaa acatgacata
     1861 cctatttatg tttctaattt tgaaggaata ttttcagaaa aagcagcacg tgattggcgc
     1921 tatgcttttt ttaaaagtat tatgttaaaa aataactatt cagctttagt aacagctcac
     1981 cattcagatg atcaagcaga aactattttg atgaggctaa ttagaggaag ccgattgagg
     2041 cacttgtcgg gtataaaaag cgtgcaacca tttgccaatg gtcaacttat aagacctttt
     2101 ttaactttct caaaaaagga cttgccagaa atttttcatt ttgaagattc ttcaaatagg
     2161 gaattatcat ttttaagaaa tagagttaga aataattatt taccattgtt aaagcaggaa
     2221 aatcctaggt tcattcaggg attaaatcaa ttagcacttg aaaatagctt actttttcaa
     2281 gcttttaagg agctaacaaa tcatattact accactgatt taacagaatt taatgagcaa
     2341 tctaagtcta ttcaatactt tt
//
LOCUS       DATWVB010000089         2311 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.089, whole genome shotgun sequence.
ACCESSION   DATWVB010000089 DATWVB010000000
VERSION     DATWVB010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2311
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.089"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            50..1238
                     /gene="hasA"
                     /locus_tag="VCX65_001744"
                     /pseudo
     CDS             50..1238
                     /gene="hasA"
                     /locus_tag="VCX65_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106926.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
     gene            1274..>2311
                     /gene="hasB"
                     /locus_tag="VCX65_001745"
     CDS             1274..>2311
                     /gene="hasB"
                     /locus_tag="VCX65_001745"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="HEP5054179.1"
                     /translation="MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSP
                     IQDEYIEDYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIK
                     EVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFDNTYLALRVAYF
                     NELDTYAESRKLNSHMIIQGISHDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIP
                     QTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNSDNFRESAIKDV
                     IDILKSKDIKII"
BASE COUNT          785 a          365 c          386 g          775 t
ORIGIN      
        1 aattgtttta tcctttattt ttttgatatc tatcttgatt tatctaaata tgtatctatt
       61 tggaacatca actgtaggaa tttatggagt aatattaata acctatctag ttattaaact
      121 tggattatct ttcctttatg agccatttaa aggaaatcca catgactata aagttgctgc
      181 cgtaattcct tcttaataat gaagatgccg agtcattatt agaaactctt aaaagtgtgt
      241 tagcacagac ctatccgtta tcagaaattt atattgttga tgatgggagt tcaaacacag
      301 atgcaataca attaattgaa gagtatgtaa atagagaagt ggatatttgt cgaaacgtta
      361 tcgttcaccg ttcccttgtc aataaaggaa aacgccatgc tcaagcgtgg gcatttgaaa
      421 gatctgacgc tgacgttttt ttaaccgtag attcagatac ttatatctat ccaaatgcct
      481 tagaagaact cctaaaaagc ttcaatgata agacagttta tgctgcaaca ggacatttga
      541 atgctagaaa cagacaaact gatctattaa cgcgacttac agatatccgt tacgataatg
      601 cctttggggt ggagcgtgct gctcaatcat taacaggtaa tattttagtt tgctcaggac
      661 cattgagtat ttatcgacgt gaagtgatta ttcctaactt agagcgctat aaaaatcaaa
      721 cattcctagg tttacctgtt agcattgggg atgatcgatg tttaacaaat tatgctattg
      781 atttaggacg cactgtctac caatcaacag ctagatgtga tactgatgta cctttccaat
      841 taaaaagtta tttaaagcaa caaaatcgat ggaataaatc tttttttaga gaatctatta
      901 tttctgttaa aaaaattctt tctaatccca tcgttgcctt atggactatt ttcgaagtcg
      961 ttatgtttat gatgttgatt gtcgcaattg ggaatctttt gtttaatcaa gctattcaat
     1021 tagaccttat taaacttttt gcctttttat ccatcatctt tatcgttgct ttatgtcgta
     1081 atgttcatta tatggtcaaa catcctgcta gttttttgtt atctcctctg tatggaatat
     1141 tacacttgtt tgtcttacag cccctaaaac tttattcttt atgcaccatt aaaaatacgg
     1201 aatggggaac acgtaaaaag gtcactattt ttaaataata tatgcatcga gtagttagag
     1261 aaggagtaat tttatgaaaa tagcagttgc tggatcagga tatgttggat tatcactagg
     1321 agttctttta tcacttcaaa acgaagtcac tattgttgat attcttcctt ctaaagttga
     1381 taagattaat aatggcttat caccaattca agatgaatat attgaagatt acttaaaaag
     1441 taagcaatta tctattaaag caactttaga tagcaaagca gcttataaag aagcggaact
     1501 ggtcattatt gccacaccta caaattacaa cagtagaatt aattattttg atacacagca
     1561 tgttgaaaca gttatcaaag aggtactaag cgttaatagc catgcaactc ttatcatcaa
     1621 atcaacaatt ccaataggtt tcattactga aatgagacag aaattccaaa ctgatcgtat
     1681 tatcttcagc cctgaatttt taagagagtc taaagcttta tatgacaact tatatccaag
     1741 ccgaattatt gtttcttgtg aagaaaacga ttctccaaaa gtaaaggcag acgcagaaaa
     1801 atttgcactt ttattaaagt ctgcagctaa aaaaaataat gtaccagtac ttattatggg
     1861 agcttcagaa gctgaagcag taaaactatt tgacaatact tatttagcgt taagggtagc
     1921 ttattttaat gagttagaca cttacgcaga atcgagaaaa ttaaatagtc acatgattat
     1981 tcaaggaatt tctcatgatg atcgaatagg aatgcattat aataacccat catttggtta
     2041 tggaggttat tgtctaccta aagatacgaa gcaattattg gcaaattaca ataatattcc
     2101 ccaaacgcta attgaagcta tcgtttcatc aaataatgtg cgcaagtcct atattgctaa
     2161 gcaaattatc aacgtcttag aagagcggga gtccccagta aaagtagtcg gggtttaccg
     2221 tttaattatg aaaagtaact cagataattt tagagaaagt gctatcaaag atgttattga
     2281 cattcttaaa agtaaagaca ttaagataat t
//
LOCUS       DATWVB010000090         2194 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.090, whole genome shotgun sequence.
ACCESSION   DATWVB010000090 DATWVB010000000
VERSION     DATWVB010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2194
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.090"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            19..498
                     /gene="rlmH"
                     /locus_tag="VCX65_001746"
     CDS             19..498
                     /gene="rlmH"
                     /locus_tag="VCX65_001746"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEP5054180.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            complement(656..729)
                     /locus_tag="VCX65_001747"
     tRNA            complement(656..729)
                     /locus_tag="VCX65_001747"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(693..695),aa:Arg,seq:tct)
     gene            894..1668
                     /locus_tag="VCX65_001748"
                     /pseudo
     CDS             894..1668
                     /locus_tag="VCX65_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1863..1934
                     /locus_tag="VCX65_001749"
     tRNA            1863..1934
                     /locus_tag="VCX65_001749"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1896..1898,aa:Glu,seq:ttc)
     gene            1968..2041
                     /locus_tag="VCX65_001750"
     tRNA            1968..2041
                     /locus_tag="VCX65_001750"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2002..2004,aa:Asn,seq:gtt)
BASE COUNT          744 a          388 c          404 g          658 t
ORIGIN      
        1 ttgtgataca attaagctat gaaagtgaaa ctaatttgtg ttggaaaact aaaagaaaga
       61 taccttaaag atggtatttc agaatatcaa aaaagacttt cccgtttttg tcaattcgaa
      121 atgattgagt taactgatga aagaacacca gataaagcaa gttttgctga taatcaattg
      181 attatgagta aagaagctca gcgaatccat aaaaaaattg gggaacgtga ttttgtaatt
      241 gcattagcta ttgaaggaaa acagtttcct tcagagacat ttagtgaatt aatatcaggg
      301 gttactgtta agggatattc aactatcacg tttattattg gtgggagtct tggattagat
      361 tcaattatta aaaaaagagc taatatgcta atgagttttg gattgttaac cttacctcat
      421 cagttaatgc gtctagttct tactgagcaa atttatcgtg cttttatgat tacacaaggc
      481 agtccttatc ataagtaaga gagtgtgaac tggaataact aactcttacc actttattag
      541 ataatagttc ggtataatta aaagcaaata ttaaaaaaag acgtactaaa tcctatcttt
      601 tcaatacact aaggtaaata caaaaaaaag cactaaaaca gtgctttttt atctttgatc
      661 ccagcaggat tcgaacctgc gaccgttcgc ttagaaggcg aatgctctat ccagctgagc
      721 tatgagacct taaccacatc attttaacaa aaattatcta aaactgtcaa tatttatttt
      781 gaaaaaacta gaaaataaca taatatcccg cgttgtaaaa tgaagtgcaa caaaaaagac
      841 atgttcatct gatatactag aattccccaa ttcagtatgg aaagcagatg aacatgtcta
      901 atattaattc taccagaaag tcatcctatt ctcatctttc agccacagaa cggggtgaaa
      961 ttgctgctta tcttaaaatg ggaaagaaac ccgttgagat tgctcgactt ctggggcgtc
     1021 actgttctac aatctgccga gaaataaaac gtggttcagt agatcaggta aaggataaga
     1081 atggaaaaca aaccttcttc aacgcctatt tcgctgatag tgggcaacgt gtctattaaa
     1141 ccaatcgatt tgcctaaggt ggttagtatc agaaaacgtt ctaagaaagt catgaagacg
     1201 aataagaaga ctttaggtaa atctatcgaa gaacgtccag aatatattaa tgatcgttct
     1261 gaatttgggc attgggagat tgatttggtt ctcggcaaga aaaccaaaag tgaagctgtt
     1321 atgttgactt tggtagagcg ccagacacgc tatgcactag gagttaagct agaagacaag
     1381 cagtcccaaa ccattaaccg tgctgtcacg catctcatca gtcagtatcc tattgcatcc
     1441 atcacagcgg ataatggttc tgagtttagt ttactctcag acttaaaagc tgttgacgtt
     1501 tactttgcac atccctattc ttcacatgag agaggaacaa gcgagaactt caatggcctc
     1561 ctcagagaat atgtccctaa aggagtctca cttaatccac taacctctga agaacttgac
     1621 aatgatatta ctgccatcaa tgagcgccta agacgacttc ttcaatagca atcctcaaaa
     1681 ttcctgtttg agctatcccg aacagcttaa cctctggaac tctagttatc tatgaactcg
     1741 ttgcacttga cttgacaact tgcggtttaa aaaaaatcaa atttttttaa aaaaagtata
     1801 gacaaaaaaa atcaatctgc tataatagta agagtgttaa ggagatatcc tccaaaactt
     1861 ctggtccgtt ggtcaagggg ttaagacacc gccttttcac ggcggtaaca cgggttcgaa
     1921 tcccgtacgg actatcgcaa ttgtcatttt ggcaattttt ttctttttcc ggcatagctc
     1981 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactggcgga
     2041 gtgataagat atttcttaag ataatcttag gattttttta tttagtaaaa cagatactca
     2101 ggtcaaatac tcaatttact aattattaaa ccactaaata cagcattgtg aactaacagg
     2161 attgtatttt gcataaaaat agaagttctg ttct
//
LOCUS       DATWVB010000091         1986 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.091, whole genome shotgun sequence.
ACCESSION   DATWVB010000091 DATWVB010000000
VERSION     DATWVB010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1986
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.091"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..253
                     /locus_tag="VCX65_001751"
     CDS             <1..253
                     /locus_tag="VCX65_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEP5054181.1"
                     /translation="IKNKIDDTEERLRQLKNQEKKILKQDIEKRRKERTHRLITRGAI
                     LESLIENAEELTDEEIKILLEEAIKTKEFKETLKLMREN"
     gene            721..1095
                     /locus_tag="VCX65_001752"
     CDS             721..1095
                     /locus_tag="VCX65_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005957761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054182.1"
                     /translation="MSCIMSQMNTGKIVFPSILAMMLLQSIVASIASLIFPAGLIGAK
                     VTEKLYTGKSYIVFLVFSSIIPAIYFTAIMSISGLLRMKGYDENFWKIYFSSFPINVV
                     FGYFSSIFWNVILDKFLRRKEA"
     gene            1097..1522
                     /locus_tag="VCX65_001753"
     CDS             1097..1522
                     /locus_tag="VCX65_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002840511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP5054183.1"
                     /translation="MNKSIGKLITYLSRCIQQELKNVVVPFDISVGEEPYYMALTKQD
                     GLTQDELTKLVKVDKAATTRMVKSLEQKGYITRETDPKDKRNKKIYLTERGRLKYEPL
                     SRALKEFNQKLTSEWTDEQYKIVYQSLEMLQKKFEIDNK"
     gene            1797..1895
                     /locus_tag="VCX65_001754"
                     /pseudo
     CDS             1797..1895
                     /locus_tag="VCX65_001754"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          795 a          289 c          351 g          551 t
ORIGIN      
        1 aataaaaaat aaaattgacg atacagaaga aagattaagg caactaaaaa atcaagaaaa
       61 aaagatatta aaacaagaca tagaaaaaag aagaaaagaa agaacacata ggctcataac
      121 aagaggagca atcttagaaa gccttataga aaatgcagaa gaactaacag atgaagaaat
      181 aaaaatccta ctagaagaag caataaagac aaaagaattt aaagaaacac taaaactaat
      241 gagagaaaat taataaaaat aaagggtgtt gtaaataatc aaatctccct tagattttct
      301 aagggcgcaa ttatacagct atcagagatt gatgcattgc gttctccgaa ggctcctaat
      361 cggagggctg tgatttgtgc gatcaatgag ccaaacggat atacttgcat attcactcgc
      421 cgaatgcccc aacagccgac agaatgtcgg cttccgcagt catggtctgc tccaaatcaa
      481 acacggacgc tacgcttccc ctgcgctggc tgccgccagc caccctttga aaggaaaaat
      541 ttttataaac agtatttact acgaagttta ccaataaaat attattttaa gagatctaag
      601 cttaaaaaca aattagttga cgcatcaact aatttgtgat atacttaagt tattcttaaa
      661 agtgaggtaa gagtaatgaa atataaacgt tatattttcc ctatattgat ggggagtaca
      721 atgagttgta ttatgtctca gatgaatact ggaaaaattg tttttccgtc tatacttgca
      781 atgatgttat tacaatctat agttgcaagt atagcatctt tgatttttcc ggctggactt
      841 ataggtgcaa aagtaacaga gaaactatat actggaaaat catatattgt ttttttagtt
      901 ttttcatcaa taattccagc gatatatttt actgcaatta tgtctataag cggattgtta
      961 agaatgaagg gatatgatga gaatttctgg aaaatatatt tttcctcatt tcctattaat
     1021 gttgtatttg gatatttttc tagtattttt tggaatgtga tattggacaa atttttaaga
     1081 agaaaagagg cataaagtga acaaaagcat tggaaaactt ataacttatt tatcaagatg
     1141 tattcagcaa gaattaaaaa atgtagttgt tccatttgat ataagtgtcg gagaagagcc
     1201 ttattacatg gcacttacaa aacaggatgg attgactcag gatgaattaa caaaacttgt
     1261 gaaagtagat aaggctgcta cgactcgaat ggttaaatca ttagagcaaa agggatatat
     1321 cacacgagaa acagacccta aagataagag aaacaaaaaa atatatctta cagaaagggg
     1381 acgattaaaa tatgaacctt taagtagagc attaaaagaa tttaatcaga agttaacatc
     1441 agaatggaca gatgaacaat ataaaatcgt ttatcaaagt ctggaaatgc tacaaaaaaa
     1501 atttgagatt gataataaat aagttttaat ttattgcccc tctacacatc gggtcaactt
     1561 gccacgaact ttcacaacta aatacccacc gctaaaacag cggcacacca agcaggaaat
     1621 ctgaaaaagg tctcctggta tggatacaat aaataataag taatcatagg aggattttaa
     1681 attagctaga cactacgaag aagacttcaa aaggcaaata gtagaaatct ttaatcaagg
     1741 taacaacaca tataaaaaat tgggagaaga atacgatata gcaccgtcaa taatcagagt
     1801 atgtttattg gaacaatagc ctaagggtta atggatcatt aggttacttg acaccagtta
     1861 aatataggca atcaagatta actagtagtt attagttaat ctaaaattag tacgttcgat
     1921 tttagattgt acaaataggt gttgacaatc cacactaagc tgaaaaacga ttagaaataa
     1981 aaatct
//
LOCUS       DATWVB010000092         1946 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.092, whole genome shotgun sequence.
ACCESSION   DATWVB010000092 DATWVB010000000
VERSION     DATWVB010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1946
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.092"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(317..1573)
                     /locus_tag="VCX65_001755"
     CDS             complement(317..1573)
                     /locus_tag="VCX65_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEP5054184.1"
                     /translation="MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDSMQPI
                     SSTQGNRANTSKKWYDINEYGLIPVDISFEAAKKDFKEEVEKSLLSEEQQKTYNQKIE
                     AARNKDDLLLTYHSEYSKDIKKHSTSTEPVEASVQETQASVSDSMVTDDSTSVTADSP
                     EKTPSTETPAPSIPEVPEAPASSPESEESSVASSEETSSPETPVAPEAPALSEAPAQP
                     AESEESSVAAPSEETPSPETPAAPETPEEPAAPSPSPESEEPSVAASSEETPSPETPA
                     APETPEEPAAPAQPAESEESSVAATTSPSPSTPAESETQTPPAVTKDSDKPSSAAEKP
                     AASSLVSEQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVRAHESGKYLPSTGEKAQP
                     LFIATMTLMSLFGSLLVTKRQKETKK"
     gene            complement(1670..>1946)
                     /locus_tag="VCX65_001756"
     CDS             complement(1670..>1946)
                     /locus_tag="VCX65_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054185.1"
                     /translation="SGQTPNKKPETKPEKDSSGQTPGKTPQKGQPSRALEKRSSKRAL
                     ATKASTRDQLPTTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED"
BASE COUNT          486 a          360 c          430 g          670 t
ORIGIN      
        1 caatcatcaa tagaaataat aaaatcaatc atcgtagtca cctcatctat agtgtactac
       61 tttgattgat tttgtcatta tgaatctagt tttctgaaaa aaaagtttct tcatgcgttt
      121 ggcgtgccat cttttatcaa tatatgataa aatcacagca actgaagaga taagcaaaag
      181 acaattgttg acagctattt gtcctaactt ctttttgatg aggcagcaca tctaaaaaaa
      241 tagagagaac caaattggtt ctctctatta aataagctct tatcagttta agtaatacta
      301 ttcagtttaa gtaatactat tttttagttt ctttttggcg ttttgtgact aaaagactgc
      361 caaatagaga catcaaagtc atagtagcta taaagagtgg ctgtgctttt tcacctgttg
      421 aaggcaagta cttacctgac tcatgggccc taacctgtct tgacaatgag cgatttggag
      481 agtaagactg ttcttgctct tcttttttat cagaagatct ctttgaagtt ggttgttgaa
      541 cggtttgttc tgaaacaagt gaagaggctg ctggtttttc agctgctgaa gatggcttat
      601 cagagtcttt agtaacagct ggtggcgtct gagtctctga ttcggctgga gttgatggag
      661 acgggcttgt cgtagctgct actgaagatt cttcactctc agctggttga gctggagctg
      721 ctggttcttc aggagtttct ggagccgctg gagtttctgg agatggggtt tcctcagaag
      781 aagctgctac tgaaggttcc tcactctcag gtgatggaga tggagctgct ggctcttcag
      841 gagtttctgg ggccgctgga gtttctggag atggggtttc ctcagaagga gctgctactg
      901 aagactcctc actctcagct ggttgagctg gagcctcaga taaagctggg gcttctgggg
      961 ccactggagt ttctggagat gaggtttcct cagaagatgc tactgaagac tcctcactct
     1021 caggtgatga agctggggct tctgggacct ctggaattga tggagccggt gtttctgtag
     1081 atggtgtttt ctcaggagaa tcagccgtaa ctgatgttga atcatctgtc accatcgaat
     1141 ctgaaactga tgcctgtgtc tcctgcacag atgcctcaac tggctcagta gacgttgagt
     1201 gtttcttaat atctttagag tactcactat gatacgttaa caataggtcg tctttgtttc
     1261 ttgcagcttc aattttttga ttatacgttt tctgttgttc ttcagacaaa agtgattttt
     1321 ctacttcttc tttaaaatct tttttggcag cttcaaagct tatatctaca ggaataagac
     1381 catactcatt aatatcatac cattttttgg atgtattggc tctgtttcct tgagtcgaag
     1441 agattggctg catgctatct acggcatagg caacttttcc caaaaagaga ctcgcaattg
     1501 ctatactcgt taccccaacg ctcagtttgc gaatggaata gcggctgtgt ttgttatttt
     1561 ctgctctacg catattgtcc tcacatatct atttttatac tgctatgcct tcttttgaaa
     1621 agaagactga tctaactcat catcaatagt agccatctga tcagttgtac taatcttcag
     1681 tgcgttttgt tttaaagata tgagctacta atcccaagaa gaaagtggtc ataactaact
     1741 taaggagatg taaacgattt gtatccttgt cattagtcgt tggtaactga tctcttgttg
     1801 atgcttttgt agctaaagca cgcttagaag atcgtttctc tagagcacga gaaggttgac
     1861 ctttttgagg agttttacct ggtgtttgac ctgaactatc tttttctggt ttagtttctg
     1921 gttttttatt tggtgtttga cctgaa
//
LOCUS       DATWVB010000093         1791 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.093, whole genome shotgun sequence.
ACCESSION   DATWVB010000093 DATWVB010000000
VERSION     DATWVB010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1791
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.093"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(121..1602)
                     /gene="guaB"
                     /locus_tag="VCX65_001757"
     CDS             complement(121..1602)
                     /gene="guaB"
                     /locus_tag="VCX65_001757"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEP5054186.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
BASE COUNT          572 a          395 c          299 g          525 t
ORIGIN      
        1 ttatttacta agaaaaaaca ataaaagtta tccgaaaatt gttattatat tttatcattt
       61 tttaatataa aaaaagagct ggcacaatat gtcagccctt aaagttacta aattaaatta
      121 tcagtgcaca gaatagtttg gtgcttcatt tgtgatttgg acatcatgcg gatgactttc
      181 aatcaagcct gcacctgaca tttcaacaaa ttgagcattt tcatgtaatt cttgaatgtc
      241 acctgcgcca acatagccca tacctgagcg gataccacct aacatttgga agacaatatc
      301 tgaagcagct cctttataag caacacggcc ttcaatacct tctggaacta gtttattagc
      361 ttcatttacg gaaccttgga agtaacgatc gcttgatcct ttcttcatag ctgcaatgga
      421 acccattcca cgataagttt tgaacttacg gccttggtag atttcagttt cacctggagc
      481 ttcatcagta cctgcaaaca ttgatccaag cataacagca ttaccgccgg ctgcaagagc
      541 cttaacaata tcgccagaat acttgatacc accatcagca ataatcgttt tgccatattc
      601 acgagcaaca gcagcagcat cgtaaatagc agtcacttga ggaacaccga cacctgcaac
      661 cacacgagtg gtacagatag atccgggacc aatacccact ttaacaacat caacacctgc
      721 atcataaaga gcacgcgcac cttcagcagt ggcaatattt ccagcaatca aagtacgatt
      781 tgggaaatga gcacgaatct cagcaatttt acgaagaaca ccagccgaat gaccatgagc
      841 tgtgtcaata acaatcgcat ctgcaccagc ttcaaacaag gcctcggcac gctcaaaagt
      901 atctgaggta acacctaccg cagcagcgac cagaagacga ccaaattcat ctttagcagc
      961 atgtgggaat tcgattactt tttcaatatc tttgatagtg attaaaccag acagacgacc
     1021 gctattatca accaaaggaa gtttttcaat acggtgttca tgaagaatac gttctgcagt
     1081 ttcaagatct gtaccaacag cagccgtaac gaggtgctca ctagtcatat gttcagagat
     1141 tggtgcattg taatcagaaa taaaacgcat atcacgatta gtaatgatac cgaccaactt
     1201 acggtttgct aaagtttcaa caattggcac accactgata cggtagcgct gcattaattc
     1261 ttcagcttct gaaaccttgt gttcaggtgt taagaagaat ggatcaatga tgacaccatt
     1321 ttcagaacgt tttaccttgc gaacttcttc tgcttgctca gtaatagaca tgtttttatg
     1381 aataacacct aaaccacccg cacgcgcaat tgcaatagcc attttactac cagtaaccgt
     1441 atccatagct gctgtaataa taggaatatt taatgtcaaa ttgtctgcga gttttgtctt
     1501 taaatcaact tcatttggaa gaacatgact ctctgccgga ataagcaaga catcgtcaaa
     1561 agtgtagcct tttttcaaaa atttagtgtc ccaatttgac atccagacaa tcctcttttc
     1621 ttttattttt agggaatatt accctggtct attttttatt gttactatca tatcacgcta
     1681 aaatcatttg tcaataaaat attcctacag ctgaagtcac tatcagcata atatattagt
     1741 attatccgtt ttttattaat caaaaaattc atttgggtct tatttttaat c
//
LOCUS       DATWVB010000094         1670 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.094, whole genome shotgun sequence.
ACCESSION   DATWVB010000094 DATWVB010000000
VERSION     DATWVB010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1670
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.094"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..676)
                     /locus_tag="VCX65_001758"
     CDS             complement(<1..676)
                     /locus_tag="VCX65_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEP5054187.1"
                     /translation="MTPQIKQIVDYIADSFINYEQIVAESENKVLINIESKYRNTFFD
                     KSLSHGVPSLILMYSSLYKVTKDERYLTFSNIYVEKLVDIISRDGIESPSLYAGTAGI
                     ALAIKEASISGKYYPKLLSSLNCLLKEQIKDKLVVSFSNIEKGIIEPYDYDMVNGFSG
                     ITNYLLLEQEFFSVELNQIGNYLLKYIETILNKVTNCSEDREAEFDLGIAHGITGPML
                     ILAKLKS"
     gene            complement(660..>1670)
                     /locus_tag="VCX65_001759"
     CDS             complement(660..>1670)
                     /locus_tag="VCX65_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP5054188.1"
                     /translation="AIQSIIMFLAVREAFLGILLVGNVTTFIRSLSTMQTSTQNIVNN
                     IYSFYNGSLYMELLYDFTHDELVHNPIIESTVDTIQSVEFERVSFSYNGKDNVINDIS
                     FSIKAGERLAIVGENGSGKSTIFKLACGLYDNYEGNIYINGINLRSIQKKSYYKRISA
                     LFQDFLKYELTLRENVGLGELSKLYSDEDLISALKYTGVDSIFYFNQEKLNQIDLEQQ
                     LGNWFEDGRQLSGGQWQKIALSRVYLKEADCYLLDEPSSALDPESETKIFKTFFELSQ
                     NKIGIFITHKPSITQSVNKILYLDNGCIAETGSFADLNIKGMKFKNLLDKEIGATYDT
                     SN"
BASE COUNT          559 a          301 c          196 g          614 t
ORIGIN      
        1 ctgattttaa ttttgctagg attagcatag gaccagtaat tccatgtgca attcctagat
       61 caaattcagc ttctctatct tcagaacaat tagttacctt atttaaaatt gtctcaatat
      121 atttcaaaag ataatttcca atttgattta actctacaga aaaaaattct tgttcaagga
      181 gtaagtaatt agttattcca ctaaatccgt taaccatatc ataatcatat ggctcaataa
      241 ttcctttctc aatattagaa aaacttacta ccaatttgtc tttaatttgt tcttttagaa
      301 gacaatttaa ggatgataat aatttcggat aatactttcc agatatactc gcttctttaa
      361 tagctaatgc aatacctgca gtgccagcat agagagacgg agattctata ccatctctag
      421 agattatgtc tactaatttc tcaacgtata tattggagaa tgttagatat ctctcatctt
      481 ttgtcacttt atatagtgaa ctatacatta agattaatga tggcacacca tgactcagag
      541 atttatcaaa aaaggtattt ctatatttag attcaatatt aattagtact ttattctcac
      601 tttcagctac tatctgttca taatttataa aactatctgc aatgtaatct actatctgtt
      661 taatttgagg tgtcatatgt ggctccaatt tctttatcta ataagttttt aaacttcatt
      721 cctttaatat ttaaatcagc gaaacttcct gtttcagcta tacatccatt atctagatac
      781 aaaattttat tcacagattg agtaatgctt ggcttatgcg taataaaaat accaatttta
      841 ttttgcgata attcaaaaaa tgttttaaaa atttttgttt cagactcagg atctaacgca
      901 gaactaggct catctagcaa atagcaatcc gcttctttga gatatactct tgataatgca
      961 attttttgcc actgtccacc agataactgt ctcccatcct caaaccaatt ccctaattgc
     1021 tgttccagat ctatctgatt taatttttcc tgattaaagt aaaatatcga atcaactcct
     1081 gtatacttca gtgcacttat taaatcctca tcactatata actttgataa ttcacccaat
     1141 ccaacatttt cacgcagtgt caattcatac tttaaaaaat cttggaacaa tgcggatatt
     1201 ctcttgtagt atgacttttt ctgtattgaa cgaagattaa taccatttat atatatattg
     1261 ccttcataat tatcgtaaag accgcaggct aatttgaaaa tcgtactttt tccagaacca
     1321 ttttcaccaa caattgctaa cctctctcct gctttaattg aaaaacttat atcgtttatt
     1381 acattatcct taccattata tgaaaaagaa actctttcaa attcaactga ctgaattgta
     1441 tcaaccgtac tttcgattat agggttatgt actaactcat catgcgtaaa atcatacaat
     1501 aactccatgt acaatgaacc attatagaaa gaatagatat tatttactat attttgtgta
     1561 cttgtttgca ttgtagataa agaccttata aaagtagtta catttccaac taataatatt
     1621 cctagaaatg cttctctaac tgcaaggaac ataataatag attgtatagc
//
LOCUS       DATWVB010000095         1647 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.095, whole genome shotgun sequence.
ACCESSION   DATWVB010000095 DATWVB010000000
VERSION     DATWVB010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1647
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.095"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..1079)
                     /locus_tag="VCX65_001760"
     CDS             complement(<1..1079)
                     /locus_tag="VCX65_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEP5054189.1"
                     /translation="MQQSMTKVKYLWKENNNYIYSTFLTLLLTVILYANSLNLPLKFI
                     SLLFVVSTLLIVFLPKKLEVATIIFILVFGTISAIISPINDIPDEYVHYSRTVYISEG
                     DINLTNNNKKLRISKDVDKLIKQSGKTFITSNLKATKHSTREYSYPYIKGTNAYYSFS
                     YIPQALGILVGNALDLPILLTYYFGRLCNLISYAMLAFIAIKLSGSFKQVIAVVTLLP
                     MNIYLAASFNQDGFAIGLVLVTIGLFINLLSSKDKSNYNTKFFLYLVLCGLLVLSKFT
                     YFLLVCLPLFIPNEKFGKNTKLVILKKLGGLLLIFLFAAMWFRLYGQVKTPYVADFLK
                     EVNVSQQVKNMLESPIVYSSIIIRH"
     gene            complement(1060..>1647)
                     /locus_tag="VCX65_001761"
     CDS             complement(1060..>1647)
                     /locus_tag="VCX65_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEP5054190.1"
                     /translation="KYAIELMTTLGEVALGSQTIFNILFMPAFVMNLLILFFRPHITQ
                     MAIALIRGQIKEFNKIQVQLFAYLGVFSLIALVGSGLFGIPFLSILYGTNLTDYWVDF
                     MLIMLGGSIGSFATVIDNILTAMRKQQLLLIPYTGGFLISLLITNLFVMKYHILGAAL
                     SFLITMLVWLGLSIMIYLFIMNRFKKGRVNATIYD"
BASE COUNT          633 a          258 c          235 g          521 t
ORIGIN      
        1 atatgtctaa taataatact gctatagact ataggggatt ctagcatatt tttaacttgc
       61 tggctaacgt ttacttcttt tagaaaatcc gcgacatatg gggttttaac ctgtccataa
      121 agtctaaacc acattgcagc aaaaagaaaa atgagtaata gtcctcccaa ttttttcaag
      181 atgactaact tggtattttt tccgaatttt tcattaggaa taaataatgg aaggcatact
      241 aataaaaagt atgtgaattt tgaaagaact agtaacccac atagaactaa ataaaggaag
      301 aatttggtat tatagttaga tttatctttt gatgagagca agttaataaa caatccaatt
      361 gttactaaaa ctaaaccgat agcaaagccg tcttgattaa aagatgctgc taaataaatg
      421 ttcataggta gtaaagtaac aacagctatc acttgtttaa aagaaccaga caacttgata
      481 gctataaaag caagcatagc gtagctaata aggttgcaca atcttccgaa ataatatgtt
      541 aaaagtatag gtaaatccag cgcatttcct actaaaatac ccaaagcttg tggtatataa
      601 gaaaaactat aatatgcatt agttcctttg atgtaaggat agctatactc tcttgtgctg
      661 tgtttagttg ctttcaagtt tgatgttata aatgtttttc ctgactgttt aataagctta
      721 tcaacatctt tggatattct taactttttg ttattgttgg taagattaat atcaccttct
      781 gagatataaa ctgtccttga ataatgaaca tattcatcag gaatatcatt tataggtgat
      841 atgatagcag atatcgttcc aaatactaaa ataaaaatga tcgtagcaac ctctaacttt
      901 tttggtaaaa acactatcag taaagtgctc accacaaaaa gaagactaat aaattttaaa
      961 ggtagattta aactattggc atataaaata actgtcagaa gtaatgtcaa aaaagtcgaa
     1021 taaatatagt tattattttc tttccaaaga tatttaactt tagtcataga ttgttgcatt
     1081 aactcttccc ttcttaaatc tattcataat aaatagataa atcataatgg ataatcccaa
     1141 ccaaaccaac attgttatta aaaagctcaa agcagctcct aaaatatgat atttcataac
     1201 aaaaagattg gtaattaata acgaaatcaa aaatcctcct gtatatggaa taagaagaag
     1261 ttgctgtttt ctcatagcgg ttaagatatt atcgataact gtcgcaaaac taccaatcga
     1321 gcctcctagc ataatcaaca taaaatctac ccaataatcc gtaaggttag tgccatatag
     1381 tattgataaa aagggaatac caaacaaacc acttccaact aacgctatca gtgaaaaaac
     1441 tcctaaataa gcaaacaatt gaacttgtat cttattaaac tcttttattt gacctctgat
     1501 taaagcaata gccatctgtg taatatgagg tctaaaaaat aaaattagca aattcataac
     1561 aaaggctggc ataaataaaa tattaaaaat tgtttgagag cccaaagcaa cttcacctaa
     1621 agtcgtcatt agttcaatag cgtattt
//
LOCUS       DATWVB010000096         1620 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.096, whole genome shotgun sequence.
ACCESSION   DATWVB010000096 DATWVB010000000
VERSION     DATWVB010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1620
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.096"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..82
                     /locus_tag="VCX65_001762"
     CDS             <1..82
                     /locus_tag="VCX65_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5054191.1"
                     /translation="ILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(209..823)
                     /locus_tag="VCX65_001763"
     CDS             complement(209..823)
                     /locus_tag="VCX65_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEP5054192.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH"
     gene            915..1262
                     /gene="ssrA"
                     /locus_tag="VCX65_001764"
     tmRNA           915..1262
                     /gene="ssrA"
                     /locus_tag="VCX65_001764"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1414..1602)
                     /locus_tag="VCX65_001765"
     CDS             complement(1414..1602)
                     /locus_tag="VCX65_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEP5054193.1"
                     /translation="MLTYDEFKQAIDNGYITGDTVIIVRKNGQIFDYVLPGEKVRPWE
                     VVTEEVVEEVMVELDYIK"
BASE COUNT          551 a          306 c          245 g          518 t
ORIGIN      
        1 tattttggaa caatttattg aaatgataat gttttacctc gccactaatt ttattatcaa
       61 aaataaactc aacctacagt aagcgttaag actttctttt aaactatgac acactatagt
      121 ttaaaagaaa gtctttttca gtgttcatag taaataaaaa aaccgtcttc catcaaatag
      181 aagcggttta tcaaattaac accaaacctt aatgctgtaa gaaccaagat ataacatctt
      241 ttccaaaaat aaataaataa ctgtagccga taatagaaat tggtttagtt attaaaagaa
      301 tagttacaaa gcgctttaaa gacatgtccg tcaatcccgt aatcataacc ataatatcag
      361 ctggagaaac aggcgatgcc atacaaaaaa taaataattt ttcatatcct ggtgtctcca
      421 aacgcctttc atacttgtaa aatgttttgt catttacaaa gagtaagata aatttacgac
      481 cataagtctt aacaagcaag aagaggacta tactgccaat aatgatgcct acataattat
      541 aaataaaacc tgttacaggg ccaaagatta aaaaacctgc aactgtcgta aggcctccag
      601 gaatcacagg aaaaacaatc tgtatgatct gcacgacaat aaaaacaaac ggcccccata
      661 atctatagcg ctgcactaag tctttaagag cattactatc gtttaatata cctagtctat
      721 acagccaaaa agcgaggaaa aaagtaccaa ttagtgcaat aattcctaaa attttgataa
      781 ttttttgcca taatatatag gcttttgaat tacgttttgt catagactaa tcataccata
      841 agctgtaaaa ttttgctatt taaaaaaagt tttgatagaa tagttagtgt aagaaattgg
      901 ttaattatct atttggggtt gttacggatt cgacaggcat tatgaggcat gttttgcgtc
      961 ccatcggcag atgtaaattg ccagttaaat ataactgcaa aaaatacaaa ctcttacgct
     1021 ttagctgcct aaaaaccagc tagcgtgact tctacaagat tgcttgtgtc ctgttagaag
     1081 tctcaaaata gcaagctacg gttacgaaat tgtctagttt cgtgacaaga gattgataga
     1141 ctcgcaaact aatggcttga gttatgtgtc tttagtttgt taaatgaaga cataacctat
     1201 ggacgtagac aaatatgttg gcaggtgttt ggacgtgggt tcgactccca ccagctccat
     1261 caatgcttac cgtaagtaat cataacttac taaaaccttg ttacatcaag gttttttctt
     1321 tttgtcttgt tcatgagtta ccataacttt ctatattatt gacaactaaa ttgacaactc
     1381 ttcaattatt tttctgtcta ctcaaagttt tcttcatttg atatagtcta attccaccat
     1441 cacttcttcc actacctcct cggtcacaac ctcccatggt ctgactttct caccaggcaa
     1501 cacataatca aaaatctgtc cgtttttgcg cacgattatt actgtgtctc ctgtgatata
     1561 tccgttgtca attgcttgct taaattcgtc gtatgttagc ataaagcacc tccttatctt
//
LOCUS       DATWVB010000097         1572 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.097, whole genome shotgun sequence.
ACCESSION   DATWVB010000097 DATWVB010000000
VERSION     DATWVB010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1572
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.097"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..819
                     /locus_tag="VCX65_001766"
     CDS             <1..819
                     /locus_tag="VCX65_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEP5054194.1"
                     /translation="INSNQQLIEYDGNGNILVYGRLKYFKEGISLYYIGEYLAECLLI
                     EHSDTLLIHAAAVYNPLSGHSILLLGDKGAGKTTVAIRLCIEHGYHLIGNDQVIFGSN
                     SGILLTYAGTSFFKIRRTAVLSDNLLFKLFSKFFNRSLQFNKASWDDKISIFPKELGI
                     RTCNFSTEISKIYYIKTDKKEKQIYHSIWSDSLASLYLNELLGRHISGQVACFQSDNG
                     KYFSTMPLINYEKNNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            874..>1572
                     /locus_tag="VCX65_001767"
     CDS             874..>1572
                     /locus_tag="VCX65_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEP5054195.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGIDIFLTLTAILKSYKIKEIDLQSKIHKKSFEKIEKI
                     FLEVSQSFFETINDN"
BASE COUNT          586 a          185 c          284 g          517 t
ORIGIN      
        1 attaacagca atcagcaact tatagaatat gatggcaatg gaaatatttt agtttatgga
       61 agattaaagt attttaaaga aggaatttca ttatactaca ttggagagta cttagctgaa
      121 tgtctcttga ttgaacatag tgacacctta ttaattcatg cagcagcagt ttataatcct
      181 ttatctggcc attcaatttt actattagga gataaaggtg ctggaaaaac tacggttgca
      241 ataaggctgt gtatagaaca tgggtatcac cttattggta atgaccaagt aatatttggt
      301 tcgaactctg gaatactact aacttatgca gggacatctt tctttaaaat aagaaggaca
      361 gctgttttgt cggacaattt actgtttaaa ttatttagca aattttttaa ccgttcatta
      421 caatttaata aggcaagttg ggatgataaa atttcaattt tcccaaagga gttgggaata
      481 cgaacttgta atttttctac tgaaatctca aaaatttatt atataaagac agacaagaaa
      541 gaaaagcaaa tttatcattc aatttggagt gatagtttag caagtctata tctaaatgag
      601 ctattgggaa ggcatatttc tggacaggtt gcatgttttc aatcagataa tggaaaatat
      661 ttttctacaa tgcctttgat aaattatgaa aaaaataatc gggtacgaga acagatagtg
      721 aagggtattt tcgctaaaca aaaattattt aaaattacag cagctacgcc agctaagatt
      781 gcagaagcga ttatagaaaa tgttaagaaa aactcatagt gtgtgtgaat ttggggatta
      841 atatgaagta ttgaaaaagg agtaagagta attatgtttg tgataggcat tccaacttta
      901 aatgaggcag ataatatcag tagattagtt aaacaaattg atgagtatgc tgtaaattta
      961 gggaaagaaa ttattattat taattcggat agtaaaagta cagatggaac tccgcagatt
     1021 tttttagaaa ccaaaactta taacaccaaa gtttcgatag tatcagaagc taaaggaaaa
     1081 ggttataatg tgagaaatat tttcgaatat gcaataaatc atgtgccgaa tttctccggt
     1141 ttaattttga ttgatggaga cgttgtctca atgaaaaaaa tgtggttaga aaagatgttt
     1201 atagcaattg aatctggaaa tgatcttata atcccaaatt atgctagaaa atcttttgaa
     1261 ggaaatgcga caaaccattt tatttatccc atgttagtga aatttttcaa acgtgatatg
     1321 ccttatcaat gcatctctgg tgattttgga ttttcaagag gattgataaa agatttaact
     1381 ttgaagtgta attggcacaa atatacatta ggttacggga tagatatttt tttaacctta
     1441 acagctatat taaagtcata caaaattaag gaaatcgatt tacaatcaaa gattcataaa
     1501 aaaagctttg agaagattga aaaaattttt ttagaagttt cacaaagttt cttcgaaact
     1561 attaatgata at
//
LOCUS       DATWVB010000098         1442 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.098, whole genome shotgun sequence.
ACCESSION   DATWVB010000098 DATWVB010000000
VERSION     DATWVB010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1442
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.098"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            542..>1442
                     /locus_tag="VCX65_001768"
     CDS             542..>1442
                     /locus_tag="VCX65_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HEP5054196.1"
                     /translation="MKITVVGIGYVGLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSP
                     LKEAAINKLLCKAKNINATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSNIL
                     KINKKATIVIKSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNE
                     SRNSQLFLDILTDISVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNELDTFAEMQ
                     NLDSKKIIEAMGYDQRIGNSHNNPSFGFGGYCLPKDIKQLEYHFKEIPAPIITSISES
                     NLLRKIHIAKMILNSSAKTIGIYR"
BASE COUNT          521 a          192 c          244 g          485 t
ORIGIN      
        1 ttgatggatt attttaattg actttagtgg gctagatgcc agtttggatt tttgatattt
       61 gtgttgagtt taaaagataa aaacacttaa tgaaaatctg ttttttctta gaaaggggac
      121 cagtatgatt gagacgctaa tgagtacgtt ggaaatggtt agaaaaaaat tctagtagga
      181 ctgcaatcga agatgacttt gaggaatata aaaagagaaa tttaccaatc tttgtcagtg
      241 aagatgatag tgtgatctat tatagactag ggttcatttt taatgaattc tatctcaata
      301 tttcaggctg gagacaagaa ctaaagacta agcttactag tatttcttta atttctttac
      361 attttattgg tgttgttgac gaacaaaaaa agggggaata tctaggttct ttttctgata
      421 catctgaatt cttaagtaga catccaaaaa tttatatcat ctcatttagg tataaaaatc
      481 aattttatat tctttctaac aaaaaaattg atttataaaa agttttagaa tagaggttaa
      541 catgaaaatt acagttgtag gcattggata cgttggatta tcgatagggc tcctacttgc
      601 aaaggaacac gacgtcacct tttttgatat tgataataaa aaaattgatt taataaataa
      661 aaggcaatcc cctcttaaag aagcagctat aaacaaactt ttatgtaagg caaaaaatat
      721 taatgcaact tcttctgaag aattagcata taaggatgcg actttcataa tcttgtcttt
      781 gccaaccaac ctaaaattta ataagcttga tacttccatt atcgaaattt ctgtaagtaa
      841 tattttaaag ataaacaaaa aggctacaat tgtaataaag tcgacagttc caattggttt
      901 tacagaatat ttaaggaatc gatttcacta caacgatatc attttttcac ctgagttcct
      961 tagggaagga tcaactattc atgatcaatt gtatccttcg agaactatag ttggaaatga
     1021 atctagaaat tctcaattat tcttagacat actaacagat atatcggttg aaaaagactc
     1081 gccatcttta ttagttggct cttctgaagc agaagcgata aagttatttt cgaatgcata
     1141 cttggcacaa aaaattgctt tttttaatga gttggatacg tttgctgaaa tgcaaaattt
     1201 ggactcaaaa aaaattattg aggctatggg atatgaccag agaataggaa attcgcacaa
     1261 taatccttct ttcggttttg gtgggtactg tcttcctaag gatattaagc aattagagta
     1321 tcattttaaa gaaattccag caccaattat taccagtata agtgagtcta atttattaag
     1381 aaaaattcat atagcaaaaa tgattttgaa cagctcagct aaaacaatag gaatttatag
     1441 aa
//
LOCUS       DATWVB010000099         1380 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.099, whole genome shotgun sequence.
ACCESSION   DATWVB010000099 DATWVB010000000
VERSION     DATWVB010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1380
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.099"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            29..335
                     /locus_tag="VCX65_001769"
                     /pseudo
     CDS             29..335
                     /locus_tag="VCX65_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            403..>1380
                     /locus_tag="VCX65_001770"
     CDS             403..>1380
                     /locus_tag="VCX65_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP5054197.1"
                     /translation="MKLKLSVIGLFFCLIAAIGVISISDTQKPVPLPIDGAFSIQGKS
                     SLSSDEVYKKISNLSKTKNVNIYKPIVRNSGQLTYINFKNTNYEQLKPAPITGMYYTL
                     GKIDSSSLKVLTASGLKLVYAAYPWYIGGILQFDGTLRLLLMLSIYLTLLVVLFVVRT
                     RQIKEGVIRHSLGLPIYNLRRDYVISFTFELVMAGLLMIAYSYFWGSGLFTYSSKLFF
                     SLILTNLIIFQIVDIITFILFWLTIRVEKPIEIIKNKAKNSFLFIVWLVIISIIIIVS
                     GIFLQETKASQSRINRQISQLSSWNKVRNWKRLELLGIENGSINNGEINE"
BASE COUNT          465 a          182 c          246 g          487 t
ORIGIN      
        1 aaaaagattt aatagcaaag tgataacttt gcttgctgta agctctttaa gtttgggatt
       61 tacggccgta actagtgttg tcagtgcggc aacagcacat ccagctccat ctccaattat
      121 tgatgaatgg aattatggag taagtgacaa ctatggttat tctaattatt atgttaaatc
      181 tccaaacaat attggttcaa aatcttcgat aactaattat tggggatcca ttaaggcatc
      241 tgattctcaa aaaatacggg tgggcactgt caagttcaaa aaaagcttgg aatgatattc
      301 ggttgaatgc acattggaat tactttaatt tttagaaatg gtatatgcaa gctaaagacc
      361 caataattat tatagggtct tttataatat aggaagttgt ttatgaaatt aaaattatct
      421 gtcattggat tattcttttg cttaattgct gcgataggtg ttatcagtat tagtgatact
      481 caaaaaccgg tacctttacc aattgatggt gccttttcaa tccaaggaaa aagtagcctt
      541 tctagtgacg aagtttacaa aaagattagt aatctatcaa aaacgaaaaa cgttaatatt
      601 tacaagccta tagttcgtaa ctcaggtcag ttgacttata tcaattttaa aaatacaaat
      661 tatgaacaat taaaacctgc accgataaca ggcatgtatt ataccttagg taaaatagat
      721 tcaagtagct taaaggtact tacagcttca ggtttgaaac ttgtttatgc agcctatcct
      781 tggtatatag gggggatttt acaatttgat gggactttaa ggttgttatt gatgctatca
      841 atttacttaa cattattagt tgttttattt gttgttagaa cgaggcagat taaagaagga
      901 gtgataagac attctttagg attgcctata tataacttaa gaagagatta tgtcatttct
      961 tttacttttg aattggttat ggctggttta ttaatgattg cctacagcta tttttgggga
     1021 agtggcctct ttacttacag ttctaagtta tttttctctc taattttaac taatcttata
     1081 atattccaga ttgttgacat tatcactttt attttatttt ggctaactat tagggttgag
     1141 aaacctattg aaattataaa aaataaagca aaaaatagtt ttctttttat tgtatggctt
     1201 gtaattattt ctattataat aatcgtctca ggaatctttt tacaagaaac aaaggctagt
     1261 caatcaagga taaatagaca gataagtcaa ctatcttcat ggaacaaagt aagaaactgg
     1321 aaaagactag agttgttggg gattgaaaat ggctctatta ataatgggga aataaatgag
//
LOCUS       DATWVB010000100         1349 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.100, whole genome shotgun sequence.
ACCESSION   DATWVB010000100 DATWVB010000000
VERSION     DATWVB010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.100"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            431..>1349
                     /locus_tag="VCX65_001771"
     CDS             431..>1349
                     /locus_tag="VCX65_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEP5054198.1"
                     /translation="MTDSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVIHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERFIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKILNKNGKPKTRKVELTIWNDKGNVEKWRENFSDLCNEYLAKNKIEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNDLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPK"
BASE COUNT          629 a          175 c          233 g          312 t
ORIGIN      
        1 tttataagtt aatgaaaatg ttaaatgatg aagaaataag attaaacata atggaaattt
       61 tagaagaaag agtagatgat gatgtagaaa aatcacctaa agatgaaata acataattgt
      121 cccttggtta caagggcgca attatacacc ctaaagggtg cttgcgtgcc tttagagcaa
      181 aacccttgca gggagcaaca accattcgtt ttttaaaagt caagggtaaa taaactcgct
      241 aaggctcgcc attgactttt aaaatttgaa atgaacaaaa caattaagcc gacatactga
      301 aacaacaaaa attaattcag tagtcggctt tttctattct atcatttcaa aacgctcatt
      361 cacaaagagg atataaaaat ctattaagcc tccacctaaa acaacaaaaa aagaaaggaa
      421 gtgataaaaa atgacagaca gttttcattt ttcagtaaac ataatatcaa gaggaaaagg
      481 gaaaagtgca gtagcaagtg cagcatatat aagtggagaa aaaataaaaa atgaatggga
      541 cggagtaatc catgactaca caagaaaaga aaaaatatta gtaaaaaata taatattgcc
      601 tgatcatata ccaaaagaat ttaatgatag gtctacatta tggaataaag tagaaatggc
      661 agaaaaaaat tctaatgcac aactagcaag acaattcata ataggactac caaaagaatt
      721 atctttaagt gaaaataaaa acctagtcga aagatttata aaagaaaatc taacatcaca
      781 aggaatgata gtagattatg caatccatga tgagagtcaa gacaaaaatg gaaatatcca
      841 ttgtcatata atgaccataa tgcgaccaat aaacgaaaaa ggagagttct tagcaaagtc
      901 aaaaaaagaa tatatcctag atgaaaaagg agaaaagatt ttaaacaaaa atggaaaacc
      961 taaaacaaga aaagtagaac taacaatctg gaatgataag ggcaatgtag aaaaatggag
     1021 agaaaatttt tcagaccttt gcaatgaata tctagcaaaa aacaagatag aaaaaagagt
     1081 agaccatagg agttttaaaa gacaaaattc tgattattta ccgacaatcc atttaggatc
     1141 agcagcaagt gcaatggaaa gaaagggaat agaaactgac aaaggaaact ataatagaga
     1201 aataagaaaa tataacgacc ttgtaaagac aataaaagaa gagataaaaa cattaaaggg
     1261 ttggatagga aatctattag ataacctatc tactgcttat gaaaaattta aggatataga
     1321 aagagataag gtaatagaca accctaaac
//
LOCUS       DATWVB010000101         1324 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.101, whole genome shotgun sequence.
ACCESSION   DATWVB010000101 DATWVB010000000
VERSION     DATWVB010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1324
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.101"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(205..1119)
                     /gene="hasC"
                     /locus_tag="VCX65_001772"
     CDS             complement(205..1119)
                     /gene="hasC"
                     /locus_tag="VCX65_001772"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HEP5054199.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     DILERQTPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PEVKEDLKNYIIKLGKALEKSKVPTHSK"
BASE COUNT          370 a          251 c          249 g          454 t
ORIGIN      
        1 ctatttagtt ttgaagttct tgttaattag ttttaacaaa agctgtactt atgtttatca
       61 tttttctacg tataaatcct attattaata tgtccctcta gtaaagttgt ataacacaaa
      121 acttttatat tttggaacgt tgacaatttt caagatataa acttaagttg ctataaacaa
      181 ggaaaaaagt aaagtaccaa cacattactt tgaatgtgtt ggtactttac ttttttccaa
      241 agcttttcct agtttgataa tgtaattttt caagtcctct ttgacctctg ggtgttctaa
      301 ggcatagtcg atagatgttt tcatgaatcc aaatttatcc ccaacatcgt aacgattacc
      361 tttaaattct cgtgcaaaga cacgctgagt tttattgagg gtatcgatag catctgtgag
      421 ttgcacttcg ttacctgctc caggggtctg tctttccaaa atatcaaaaa tttcaggggt
      481 taggaggtaa cgaccaataa tagccaaatc actaggcgca tcttctggtt gtggtttttc
      541 aacaaaggtg tctacactgt aaaggccctt gacagccttg ccttgaggag cgataacccc
      601 atagctagac acatcttcat gaggaacttt catcacagcg atagtggatg catgcgtctt
      661 gtcatagtcc tccatgagtt gtttggtgag aggtttagcg gatgcatttg taatgtccat
      721 taagtcatct ccaagcatga ccacaaaggg ttcattgccc acaaaggctt tggcttgtaa
      781 gacagcatct cccagtcctc ttgggtggct ttgacggata aaatgaaggt taatggcagt
      841 ggtttcatcc actaatttca acagttcatt tttcccctta gcttggaggt tgtattctaa
      901 ttcaaagttt gaatcaaaat ggtcctcgat agagcgttta gcttttccgg tcaccacaag
      961 gatttcctcg atgccagatt ttagcgcttc ttcgacgata aactggatgg ttggtttatc
     1021 aacgatgggc aacatctctt tggcaagagc tttggtagca ggtaaaaaac gtgttcctag
     1081 acctgcagca ggaataatgg cttttctgac tttggtcatc agtaactcct cactttttat
     1141 aatctatggc ttagtgacat tcgttttcag aacggaattc atttgacatc atgttacgtt
     1201 ttcatatgat ttttcgacta tttcatagtg ctcaatcata ccaccaactg cagttctttt
     1261 aaagtaaaaa tgaatattat tgttatagat gaagacatgg ctagtctcta ttaaaaatat
     1321 ctct
//
LOCUS       DATWVB010000102         1284 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.102, whole genome shotgun sequence.
ACCESSION   DATWVB010000102 DATWVB010000000
VERSION     DATWVB010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1284
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.102"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            60..1085
                     /locus_tag="VCX65_001773"
     CDS             60..1085
                     /locus_tag="VCX65_001773"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEP5054200.1"
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIIYSEVT
                     PYHVTSVWTKGVIPPANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWFDQNKEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKA
                     FPGLSARRIGVMPDLALDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGD
                     QSKLLTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTCANVRINHVINLWGADFDSN
                     GNLKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQ
                     DSWNQTN"
     gene            1126..>1284
                     /locus_tag="VCX65_001774"
     CDS             1126..>1284
                     /locus_tag="VCX65_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054201.1"
                     /translation="MLRTNTIAGNFFIDGQQQKTLINPIKIDKDIVTIQEFDFKIRKF
                     LMESKEIHL"
BASE COUNT          455 a          200 c          244 g          385 t
ORIGIN      
        1 atagatgtct atatgttata atctttttat aataaaatta tatagaaaaa ggtattctta
       61 tgagaaaaag atgctattca acttcagctg cagtattggc agcagtgact ttatttgctc
      121 tatcggtaga tcgtggtgtt atagcagata gtttttctgc taatcaagag attatatatt
      181 cggaagtaac accttatcac gttacttccg tttggaccaa aggagttatt cctccagcaa
      241 acttcactca aggcgaagat gtttttcacg ctccttatgt tgctaaccaa ggatggtatg
      301 atattaccaa aacattcaat ggaaaagacg atcttctttg cggggctgcc acagcaggga
      361 atatgcttca ctggtggttc gatcaaaaca aagaaaaaat tgaagcatat ctaaaaaaac
      421 acccagataa acaaaaaatc atgtttggtg atcaagaatt attggatgta agaaaagtta
      481 ttaatactaa aggtgaccaa acaaatagcg agctttttaa ttatttccga gataaagctt
      541 tccccggttt gtcagcacgc cgaattggag ttatgcctga tcttgcttta gatatgttta
      601 tcaatggtta ttacttaaat gtttataaga cacagactac tgatgtcaat agaacctatc
      661 aagagaaaga tcgccgaggt ggtatttttg acgccgtatt tacaagaggt gatcaaagta
      721 agctattgac aagtcgtcat gattttaaag aaaaaaatct caaagaaatc agtgatctca
      781 ttaagaaaga gttaaccgaa ggcaaggctc taggcctatc acacacctgc gctaacgtac
      841 gcatcaacca tgttataaac ctgtggggag ctgactttga ttctaacggg aaccttaaag
      901 ctatttatgt aacagactct gatagtaatg catctattgg tatgaagaaa tactttgttg
      961 gtgttaactc cgctggaaaa gtagctattt ctgctaaaga aataaaagaa gataatattg
     1021 gtgctcaagt actagggtta tttacacttt caacagggca agatagttgg aatcagacca
     1081 attaaagcgt atcaataaga aagattacat tcaacagatg atggtattct aaggactaat
     1141 actattgcag ggaatttttt tatagatggg caacagcaaa aaacattaat aaatcctata
     1201 aaaatcgata aggatattgt tacgattcaa gagttcgatt ttaaaataag aaaatttttg
     1261 atggaatcaa aagaaattca tttg
//
LOCUS       DATWVB010000103         1270 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.103, whole genome shotgun sequence.
ACCESSION   DATWVB010000103 DATWVB010000000
VERSION     DATWVB010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1270
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.103"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            54..827
                     /locus_tag="VCX65_001775"
     CDS             54..827
                     /locus_tag="VCX65_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP5054202.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLESLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
BASE COUNT          427 a          196 c          235 g          412 t
ORIGIN      
        1 tatgttatga tacctttaat agttataccc taagacactg ataggagata agaatgaaaa
       61 agaaagagcg tcatgaaaaa attctcgata tcttaaaagt tgacggtttt ataaaagtaa
      121 aagatattat tgatgaaatg aacatctcag atatgaccgc tagacgagat ctcgatacat
      181 tggcagataa aggattactt atcaggaccc atggtggtgc tcaatatttg gattattctt
      241 cagcaaagga cgaaggtcac gagaaaacac acactgaaaa gaaggtctta cagactaccg
      301 aaaaaaaaca aattgcacaa agagctaaaa acattattaa agacggcgaa actgtcttta
      361 taggtccagg gacaacatta gagcatctag ctgtcgaatt aaaaaataga aatatcaggg
      421 tcattacaaa tagccttcct gtttttttaa ttttgcaccc gagcactact attgatttga
      481 ttttaattgg tggtgaatgt cgtgaaatta ctggagcttt tgttggtgct attgccatta
      541 ataatctaga atcattaact ttttcaaagg cttttgttag cgcaaatgca gtttacaata
      601 attctattgc gacgtacagt gatctcgaag gagaagttca aagggttgca ttgaataatg
      661 ctgttgagaa aatccttcta gttgatagta ccaagtttga aagttatgac ttctataatt
      721 tttaccaact agatcaagtg gacttaattg tgactgataa aaatgtgaca actgatatca
      781 tagaaaagta caagaaattc tcaaaaatca taatcgctga caagtaaagg acctactcat
      841 attaaaaagc acttcagggt ttagatatat cccctgtcaa gtaaacaggg agcatatctg
      901 aaagtagtgt ttgtgttata aagaagtttc ttgctaactt attttctggt ttttttcaga
      961 cttatcagtc ttgtactgtt cctttttctg atgaataacg tggaaatagg cagacagcta
     1021 tatatttcac ctctagaatg gttgtcatta ctgtcatcaa gacatgcttg ttctttatcg
     1081 tatggagtga agctttcttt tagacatcaa catacctctt aagtagattt tggttcgtta
     1141 ccatgtctac ttaagaggtg tcttcaaagc gctttaaaac gttgatataa cagtatatta
     1201 acgttttgag aattgtgaag ctttacgagc ttttttaaga cctggttttt ggttcactcc
     1261 attatttaaa
//
LOCUS       DATWVB010000104         1253 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.104, whole genome shotgun sequence.
ACCESSION   DATWVB010000104 DATWVB010000000
VERSION     DATWVB010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1253
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.104"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>1253
                     /locus_tag="VCX65_001776"
     CDS             <1..>1253
                     /locus_tag="VCX65_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lantibiotic dehydratase"
                     /protein_id="HEP5054203.1"
                     /translation="TNDFLISDLRPPICNINSLDYLLSKLEEGTLCTDLTTLKKMIED
                     YNDLNIGEGRDLLLQIFDKMESIYKYDNGGNYLKVDSLAEYEGGFNILSETARESIER
                     LAEMFVKLNTNVKRRGGRKNSLEEYQLKFIGKYGENCSIPFVEVINKDAGIGFPEYYK
                     GGEGEAIELSDPIMQMFEKKYEEALLNGGHIEFYSKDLDDFQTDQSNSLDSFELNFNI
                     KIINNDVKLYLGANIGSGQAGRSFGRFYGLSETVRETIKNLNHQNNTNVELSFVPKQI
                     RLANVIQNYSDESYNTSFFTTSWDSENELRLEDIYIRYSDGKFHFTTIDGKNELKFTM
                     NNMLNSDSQSRVLRLLVDLSEFEYGLSHWSLFPWDILAQERVYIPEILFEDITITTAQ
                     WNLSAIREEIIHQKIFTGKKDIFNK"
BASE COUNT          474 a          135 c          245 g          399 t
ORIGIN      
        1 tacaaatgat tttttaattt cagatttaag accaccaatt tgtaatatca attccttaga
       61 ttatctacta tctaaattag aagaaggaac actatgtact gacttaacta ctttaaagaa
      121 gatgattgaa gattacaacg atttaaatat tggggaaggt agagacttac ttttgcagat
      181 ttttgataaa atggaaagta tttataaata tgataacggt ggaaattact taaaagttga
      241 ttcattagca gagtatgaag gcggttttaa tattctatct gaaacggctc gggaaagtat
      301 agaacgactc gcagagatgt ttgtaaaatt aaatacaaat gtaaagagaa gaggggggag
      361 gaaaaattca cttgaagagt atcagttgaa atttattggc aaatatggag aaaactgctc
      421 aattcctttt gttgaagtaa taaataaaga tgcaggcata ggttttcctg aatattacaa
      481 aggaggagaa ggtgaagcaa tagagttaag cgatccaata atgcaaatgt ttgaaaagaa
      541 atatgaggaa gctctattaa atggagggca tatcgaattt tattcaaaag atttagatga
      601 ttttcaaaca gatcaaagca atagtttaga ttcgtttgaa ttaaatttta atataaaaat
      661 aataaataat gatgtgaagt tatatttagg agctaatatc ggttctggac aagcaggtag
      721 aagctttgga agattctatg gattaagcga aacagtaaga gaaacaatta agaatttaaa
      781 ccatcaaaat aatacgaatg tagagttgtc atttgttcct aaacagataa gacttgcgaa
      841 tgtaattcaa aattatagtg atgagtctta taatacttca ttttttacca catcatggga
      901 ttcagagaac gaactgcgat tggaggatat ttatataaga tatagtgatg gtaagtttca
      961 ttttacaact atcgatggga aaaatgagtt gaaatttacc atgaataata tgctaaattc
     1021 cgatagccaa agcagggttt tgagattgtt ggttgattta tctgagtttg agtacggttt
     1081 atcgcattgg tcattatttc cttgggatat tttggctcag gaaagagtat atattcctga
     1141 aattttattt gaagacatta cgattaccac tgctcagtgg aatttatcag caattagaga
     1201 agagattata catcaaaaaa tatttactgg taaaaaagat atattcaata agt
//
LOCUS       DATWVB010000105         1233 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.105, whole genome shotgun sequence.
ACCESSION   DATWVB010000105 DATWVB010000000
VERSION     DATWVB010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1233
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.105"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            4..1197
                     /locus_tag="VCX65_001777"
     CDS             4..1197
                     /locus_tag="VCX65_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEP5054204.1"
                     /translation="MIDSLLLKSLHSLLGLTITVCDQNFSVIREYKSDKTISLFYNHY
                     LILSNFSKTQHDFLFHYGSLGELFLVHHIQQYYIIIGPWRSNAIDPLLLKKKLTETQI
                     NASEQDYFIDRLSQLPFFSLSQIRELLIVTNYCLTGVVKDKLSEPLHYYTKGWSNSFD
                     LDKIKQFSKQNMSSYKYQYHFENNILKAVKSGSEFLLKETVEHFSNSIVPIISGDELR
                     SEKNYSIIIYDRLSQATIQAGLDIETAYRARDRFIKETESTISLNEVLKLRDTAILFY
                     TQQVDSLKRHLETPHSQTIVAVIRYLENNLNRFIKTEEIAKECHMSESKLRKLFKQEK
                     HITIQQYFINLKIEAAKQLLDENKKVEEVSNLLGFSTSSNFSRTFKKIVGISPLEYKQ
                     KLKTI"
BASE COUNT          448 a          211 c          168 g          406 t
ORIGIN      
        1 catatgattg attctttatt gttgaaatca ttacacagtc ttctaggtct aactattact
       61 gtttgtgatc aaaatttttc tgttatcaga gagtataaat ccgataaaac tatttcactt
      121 ttttacaatc attaccttat tttaagtaac tttagtaaaa ctcaacatga ttttttattt
      181 cattatggct ctttaggaga actttttctt gtccaccata ttcaacaata ttatattatc
      241 atcggtccct ggcgtagcaa tgctattgat cctttacttc ttaagaaaaa gctgactgaa
      301 acacaaatca atgctagtga acaagactac tttattgata gactatccca attacctttc
      361 ttctcactta gtcaaatccg agaattacta atagtaacca attattgtct aactggggtt
      421 gtgaaagata aattatcaga gcccttacat tactacacga aagggtggag caactccttt
      481 gatctagata aaattaagca attttctaaa cagaatatga gttcttacaa atatcagtat
      541 cattttgaaa ataatattct aaaagctgtt aaatcaggta gtgaatttct tttgaaagaa
      601 acagtggaac actttagcaa ttctatcgta cctataatca gtggagatga attgcgatct
      661 gaaaaaaact actccatcat tatttatgat cgtctctcac aggctaccat ccaagcagga
      721 cttgatatcg aaacagctta tcgagcacga gatcgtttta taaaagaaac cgagtcaact
      781 ataagtctaa atgaagtttt aaaattacgt gatactgcta tcttattcta tactcaacaa
      841 gttgattctt taaaaagaca tctcgaaacc cctcattctc aaactattgt cgcagtgatt
      901 cgatatcttg aaaataatct aaatcgcttt attaaaacag aagaaatagc taaagaatgt
      961 cacatgagtg aatcgaagtt acgaaaacta tttaagcaag aaaaacacat cactattcaa
     1021 caatatttta taaacttaaa aatcgaagct gctaagcagt tactagacga aaataagaaa
     1081 gtagaagaag tttccaattt acttggattt tccacttctt ctaatttttc aaggacattt
     1141 aaaaaaatag tgggaattag cccactagaa tataagcaaa agcttaagac aatatagtaa
     1201 tcgaaaaata ttcattttgc ttaatattcc ctt
//
LOCUS       DATWVB010000106         1229 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.106, whole genome shotgun sequence.
ACCESSION   DATWVB010000106 DATWVB010000000
VERSION     DATWVB010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.106"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            112..>1229
                     /locus_tag="VCX65_001778"
     CDS             112..>1229
                     /locus_tag="VCX65_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEP5054205.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFAHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAI
                     KMGRFSEQLIKKTRSMLLNNALLSEDYNKNIIERIYTSS"
BASE COUNT          446 a          191 c          192 g          400 t
ORIGIN      
        1 attttactaa cactagaatc ccgacaatta agtcaaaaaa agttatcact cacctaacct
       61 gaataaaaat ggtataatcg taaggatcac actatttatt aaggaaacat tatgaaaatt
      121 gttcagggag tacaacttca tctgattaag accaaacagt ttaaaaccaa tcatattacc
      181 tttcgttttt caggtgattt gaaccaaaaa acagtagcaa aaagagtctt agtggcacag
      241 atgttagcaa cagctaatga gtgttatcca actgttaggc agtttagaga aaaattagca
      301 cgactttatg gagctagctt gtcaactaac gtgttaacaa aagggttagt tcatattgtg
      361 gatatcgata ttacttttat tcaagataga tatgcttgca atggggaaaa aatactagat
      421 gaaatgattc agtttttaaa agatatcttg ttctcacccc tattatccat cgcccagtat
      481 cagcctaaag tttttgagac tgaaaaaaat aatttgatta actacatcga gtcagataga
      541 gaggattctt tttactacag ctctcttaag gtaaaagaat tgttttattg taataagaat
      601 ctacaaatgt cagaatatgg tagcccagaa ctaattgcaa aagagactgc ctatactagc
      661 tatcaagaat ttcataaaat gctcaatgaa gatcagattg atattttcat tttaggagat
      721 tttgatgatt atcgcgttgt tcagctaatt catcaatttc cacttgataa ccgaaataaa
      781 aacctaaatt tctttcattt acaaaattct gtcaatatta ttaaagaatc tattgaaaaa
      841 agagcagttc atcaatctat tttacaatta gcttatcact tcccttcagt ttttggacaa
      901 cgtgactatt atgctttagt tcttttaaat gggttgttag gctcttttgc acattcccgt
      961 ctctttataa aaattagaga agaagaagga cttgcttata gtatagggtg tcgttttgat
     1021 agttatacag gtttatttga aatttatact ggaattgaca gtcaacatcg cactaaaacg
     1081 ttacaactaa tcatccaaga attaaatgcc attaaaatgg gacgattctc agaacaattg
     1141 attaaaaaga ccagatcgat gttgttgaat aacgccttat tatcagaaga ttataataaa
     1201 aatataattg aaagaatata cacatcttc
//
LOCUS       DATWVB010000107         1146 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.107, whole genome shotgun sequence.
ACCESSION   DATWVB010000107 DATWVB010000000
VERSION     DATWVB010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.107"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..1126)
                     /locus_tag="VCX65_001779"
     CDS             complement(<1..1126)
                     /locus_tag="VCX65_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP5054206.1"
                     /translation="MFDFANNTFLAGLNPASLSLVAVYQSLESVIGVLFNLFGGVIAD
                     SFKRKKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNVILAFMSAFSSPSYKAFTK
                     EIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKLLGIHGVLLLDGLSFLIAALLIS
                     FILPVNDEVVIKEKVTIREIFNDLKIGFKYVYSHKSIFIITVLSALVNFFLAAYNLLL
                     PYSNQMFGEISTGLYGTFLTAEAIGGFIGAILSGFVNKELSSMRLILFLSLSGLMLML
                     APPFYIMFHNAIILALSPALFSLFLSIFNIQFFSLVQKDVDNDFLGRVFGIIFTITIL
                     FMPIGTGFFSVALNPNNSFNLFIIGSCITILSLVFRILFKK"
BASE COUNT          460 a          188 c          164 g          334 t
ORIGIN      
        1 actttttaaa taatattcta aatactaatg acaatatagt aatgcacgaa ccaataataa
       61 aaagattaaa gctattgtta ggatttaatg ccaccgagaa aaagccagtc ccaataggca
      121 taaaaagaat agttattgta aagataatac caaacactct ccctaaaaaa tcgttatcaa
      181 catctttctg gacaagagaa aaaaattgaa tattaaagat ggaaagaaat aaactgaata
      241 aagctggtga caaagctaaa ataattgcat tatgaaacat aatataaaat gggggagcta
      301 acattaacat cagtcctgat aaagatagaa acaatatcaa tctcatactt gataattctt
      361 tattcacaaa accacttaat attgccccaa taaatccacc aattgcttct gctgttaaaa
      421 aagtgccata aagtccagtt gaaatttctc caaacatttg attactatag ggcaacaata
      481 aattataagc ggctagaaaa aaattaacaa gtgcagaaag aacggtaata ataaagatgg
      541 acttatggct gtaaacatat ttaaatccta tttttaaatc gttaaatatt tctctgattg
      601 tcaccttctc ctttatcacc acttcgtcat taacaggtaa aataaaggaa attagtaaag
      661 cagctattag aaatgatagt ccatccaata gtaatacacc gtgtatacca agtagcttat
      721 ataagaaaat tgctaccata ggaactgtta ctttgattac agtacttgtt gtctctagca
      781 atgaattaag ttgtgatata ctatcttttt taacaatttc ttttgtaaat gctttatagg
      841 atggactaga aaaagcactc ataaatgcca agataacatt agttagtaca atggcataaa
      901 ccaaccattg ctcttttgtt aggaacgaga gtactaagca agctgtgcca cataagatat
      961 ttgtagtaat aataattttt ttccgcttga aactgtctgc aatgactcca ccaaataaat
     1021 taaatagaac acctatgaca ctttctagag actgatatac tgcaactaat gatagagacg
     1081 ctggattaag cccagcaaga aaagtattgt tagcaaaatc aaacataaca tcgccaattc
     1141 gatata
//
LOCUS       DATWVB010000108         1079 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.108, whole genome shotgun sequence.
ACCESSION   DATWVB010000108 DATWVB010000000
VERSION     DATWVB010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1079
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.108"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..474
                     /locus_tag="VCX65_001780"
     CDS             <1..474
                     /locus_tag="VCX65_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEP5054207.1"
                     /translation="IYTSNILDLDLNYLPTRMAWCYGTPGTAVALFKMCQLIDLNFID
                     DINESLIAQMRSSDKNVYSLTMCHGLAGVTFIYDLIGKNYSSERLTRFAEELRQQIIT
                     SFSTTKVFGYTDREKFGEIEVELESIGILQGVSGIVLFLLNPYSDEELLWQRIFI"
     gene            493..>1079
                     /locus_tag="VCX65_001781"
     CDS             493..>1079
                     /locus_tag="VCX65_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic dehydratase"
                     /protein_id="HEP5054208.1"
                     /translation="MYKVFPTGMIRIPLQKQEFYNKDYEDLINDKVFMEQLLVASPSL
                     YDSVIDFDKCNEKKKQNVKVSLNSYSKRAAFRTTPFGIFTAINTVDLTKGTTSNVQKV
                     SFIKKAVPDYSWIYSLVKSYEISNLEKLSLKINTAAFTQGDRYVLPFTVNESEEDRNI
                     SFSKPIKLLVEKCKTRYIKYEELIDVFKNNYPDIVS"
BASE COUNT          403 a          130 c          192 g          354 t
ORIGIN      
        1 atttatacta gtaatatttt ggatcttgat ttaaattatc ttcctactag aatggcatgg
       61 tgttacggta cgcctggaac tgcagttgcc ctttttaaaa tgtgtcaatt gatagattta
      121 aattttattg acgatattaa tgaaagttta attgctcaga tgagaagttc agacaaaaat
      181 gtctattctc ttacaatgtg ccatggtttg gcaggagtaa cttttatata tgacttgatt
      241 ggtaaaaatt attcaagtga gaggctaact cgctttgcag aagagcttcg ccaacaaata
      301 attacatcgt tttcaactac aaaagtattt gggtatactg acagagaaaa atttggagaa
      361 atagaagttg aactggagtc aatagggata ttgcaagggg tatcagggat agtgttattc
      421 ttattaaatc cttacagtga cgaggagcta ttgtggcaaa gaatatttat ttaatttgaa
      481 aaggagaaca aaatgtataa ggtatttcca actggtatga ttcgtattcc attgcaaaaa
      541 caagaatttt ataataaaga ctatgaagat ttaataaatg ataaagtttt tatggaacaa
      601 cttttagttg ctagtcccag tctttatgat agtgtaatag attttgataa atgtaatgaa
      661 aagaaaaagc aaaatgtaaa agtctcatta aatagttatt ctaaaagagc agcgtttaga
      721 actactccat ttggtatctt tactgctatt aatacagttg atttgacaaa gggaaccact
      781 tctaatgtac aaaaggttag ttttattaaa aaagcagtcc cagattattc atggatatat
      841 tctctagtaa aatcgtatga aataagtaac cttgaaaaac tttcattaaa aataaataca
      901 gcggcgttta ctcaaggtga cagatatgta ctaccattta cagtgaatga atcagaggaa
      961 gatagaaaca taagtttttc aaaaccaatt aagttacttg tagaaaaatg taaaactcga
     1021 tatataaaat atgaagagtt aatagatgta tttaaaaata attatccaga tatagtgtc
//
LOCUS       DATWVB010000109         1019 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.109, whole genome shotgun sequence.
ACCESSION   DATWVB010000109 DATWVB010000000
VERSION     DATWVB010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1019
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.109"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            167..448
                     /locus_tag="VCX65_001782"
     CDS             167..448
                     /locus_tag="VCX65_001782"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP5054209.1"
                     /translation="MTVLNYVNAGDAKSIHNHLFHYTRQVRRHVKVITIGILSAHYYE
                     ITMLFLQAKIILDCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
     gene            complement(925..1012)
                     /locus_tag="VCX65_001783"
     tRNA            complement(925..1012)
                     /locus_tag="VCX65_001783"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(976..978),aa:Ser,seq:gct)
BASE COUNT          349 a          217 c          117 g          336 t
ORIGIN      
        1 tacaaaattg tttatcttca ctcagacacc ttatccttct tagaatgaat ttttagttac
       61 ttatccacag gttaataact tcttttcgcc taaaatatta tccacaatag tgacattttc
      121 tattatcagt tatagtataa tttcattagg aatctaaaac cttagcatca cggttttaaa
      181 ttatgtaaat gctggggacg caaaaagcat tcataatcat ctctttcatt ataccagaca
      241 ggtgagaagg catgtcaaag ttattaccat aggcatactc agtgcccact actatgagat
      301 tactatgctt tttctacagg ctaaaattat cctcgattgt tttcatatcc cccaacgtct
      361 tagacaagct ataactcgct ttcgtatccg aatcataaat acttctgcta taaaacctat
      421 cgcgtataga actctcaaac tttactgaaa actcatacag catgattcac ggaagctcat
      481 caataatagc tttattgccc aatttttcgt acgcccataa ctaacatcta gaaaagaaaa
      541 gctcttactc acaagatctc tgaatttcaa taattattcc taactctatc aactcttgct
      601 cttcccattt ttcagacaat ttttaaaatt tttctaaaag aaaagaaaac aagattagca
      661 atatacttaa actcaactac tctaaggcca aattagaaac agtcaacaac cttatcaaag
      721 ccatcaagtt aaacgtttta ctcctctaca gtagtcaaag agcctatcat tttagttatc
      781 gaaataatga acgatttaaa tattctattt agttggtttt gaagattaca aaaaaaagac
      841 gataaccgtc ttctttcccc cttatttata attcatcctt taatatgttt catttaacat
      901 attaaccaaa atatctttac aaaacggaga ataagggatt cgaacccttg cgccagttac
      961 ccgacctaac gatttagcaa accgtcctct tcagcctctt gagtaattct ccaaatata
//
LOCUS       DATWVB010000110          991 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.110, whole genome shotgun sequence.
ACCESSION   DATWVB010000110 DATWVB010000000
VERSION     DATWVB010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.110"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(19..92)
                     /locus_tag="VCX65_001784"
     tRNA            complement(19..92)
                     /locus_tag="VCX65_001784"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Ile,seq:cat)
     gene            complement(113..186)
                     /locus_tag="VCX65_001785"
     tRNA            complement(113..186)
                     /locus_tag="VCX65_001785"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(150..152),aa:Met,seq:cat)
     gene            complement(192..265)
                     /locus_tag="VCX65_001786"
     tRNA            complement(192..265)
                     /locus_tag="VCX65_001786"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(229..231),aa:Pro,seq:tgg)
     gene            complement(272..345)
                     /locus_tag="VCX65_001787"
     tRNA            complement(272..345)
                     /locus_tag="VCX65_001787"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(309..311),aa:Arg,seq:acg)
     gene            complement(362..446)
                     /locus_tag="VCX65_001788"
     tRNA            complement(362..446)
                     /locus_tag="VCX65_001788"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(410..412),aa:Leu,seq:taa)
     gene            complement(455..526)
                     /locus_tag="VCX65_001789"
     tRNA            complement(455..526)
                     /locus_tag="VCX65_001789"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(492..494),aa:Gly,seq:gcc)
     gene            complement(539..611)
                     /locus_tag="VCX65_001790"
     tRNA            complement(539..611)
                     /locus_tag="VCX65_001790"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(576..578),aa:Thr,seq:tgt)
     gene            complement(622..703)
                     /locus_tag="VCX65_001791"
     tRNA            complement(622..703)
                     /locus_tag="VCX65_001791"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(667..669),aa:Leu,seq:tag)
     gene            complement(709..781)
                     /locus_tag="VCX65_001792"
     tRNA            complement(709..781)
                     /locus_tag="VCX65_001792"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(746..748),aa:Lys,seq:ttt)
     gene            complement(813..885)
                     /locus_tag="VCX65_001793"
     tRNA            complement(813..885)
                     /locus_tag="VCX65_001793"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(850..852),aa:Asp,seq:gtc)
     gene            complement(903..975)
                     /locus_tag="VCX65_001794"
     tRNA            complement(903..975)
                     /locus_tag="VCX65_001794"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(940..942),aa:Val,seq:tac)
BASE COUNT          262 a          284 c          220 g          225 t
ORIGIN      
        1 taatgattat ctatgatatg gaccttgtag gactcgaacc tacgaccgct cggttatgag
       61 ccgagtgctc taaccagttg agctaaaggt cccaagtcat ccataaaaat aatagcggcg
      121 aaggggatcg aacccccgac ctcccgggta tgaaccggac gctctagcca gctgagctac
      181 accgccatta atcgggaaga caggattcga acctgcgaca ccttggtccc aaaccaagta
      241 ctctaccaag ctgagctact tcccgaactg atgcacccta gaggagtcga acctctaacc
      301 gcctgattcg tagtcaggta ctctatccag ttgagctaag ggtgctattt caaaaaatta
      361 atgccgagga ccggaatcga accggtacga tgtaaaccat cgcaggattt taagtcctgt
      421 gcgtctgcca gttccgccac cccggctcct caaaagcgaa cgacgggatt cgaacccgcg
      481 acccccacct tggcaaggtg atgttctacc actgaactac gttcgcaact aatctcaatg
      541 ccggctacat gacttgaaca cgcgaccctc tgattacaaa tcagatgctc taccaactga
      601 gctaagccgg ctaatctttt atgcgggtta agggacttga acccccacgc cgttaagcgc
      661 cagatcctaa atctggtgcg tctgccaatt ccgccaaacc cgcttttatg acccgtactg
      721 ggctcgaacc agtgacccat tgattaaaag tcaattgctc taccaactga gctaacgagt
      781 ctttccttca aaaaatatga ctactctttg aacggtcccg acgggaatcg aacccgcgat
      841 cttcgccgtg acagggcgac gtgataaccg ctacactacg ggacctgtat tttccaatac
      901 tatgggagtt aacgggatcg aaccgctgac cctctgcttg taaggcagat gctctcccag
      961 ctgagctaaa ctcccattga gtgtgtcatt a
//
LOCUS       DATWVB010000111          932 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.111, whole genome shotgun sequence.
ACCESSION   DATWVB010000111 DATWVB010000000
VERSION     DATWVB010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..932
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.111"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..884)
                     /locus_tag="VCX65_001795"
     CDS             complement(<1..884)
                     /locus_tag="VCX65_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP5054210.1"
                     /translation="MTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYF
                     DTENNIIKALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKRRLG
                     SIETTSLMNFYGQEEKYHTITVRVHIKNYPAVAYMMAVVNVEQLDRANERYERIIIIV
                     MSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNRLESLFRK
                     PNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENY
                     ELVAKEYGKIFYFQNQVN"
BASE COUNT          328 a          171 c          136 g          297 t
ORIGIN      
        1 ctattgactt ggttctgaaa ataaaatatt tttccatatt ctttagcaac tagttcataa
       61 ttctcaaaaa tagcattaaa aaaatctgta tctaaatgag tccactgtgg attaatgcca
      121 tcatctcgtc ttgctaaatt taataaatta gttgttaaga tgcgcatgtt gcgaacctcg
      181 tctaaactag aagcgagatg ctcactattt tctaatatcg tttcgttggg cttacgaaaa
      241 agcgattcca gacgattctg taagaccgcc aaaggggtcc ttagttcatg actagcattt
      301 tcaacaaaca ttttttgttt ttcatagctt tctaaaatag gttttctgct ccacttggct
      361 aaataaatac ttgctaaaat agaaattagc caaaaaacac tcataactat aataataatg
      421 cgctcgtaac gttcattagc gcggtctaat tgttccacat ttactactgc catcatatag
      481 gcaactgcag gataattttt gatatgaacc cttacagtta tcgtatggta tttttcttct
      541 tgtccataaa aattcattaa actggtggtt tcaatactcc ccaaccggcg tttatctaaa
      601 tgaaaatttt gatagttaga aaacgcatca aaagcattta aaattgttcc attagcacta
      661 aacaaaatga tatctgtatt agctgcaggc gttcctaata acttagaact atctgaatca
      721 ggcagcgcct taataatgtt attttcagta tcaaagtaaa aagaagatat tctagccatc
      781 gtacgattag catagctact tgcattatta ctaacagaaa ctaaactact atcaactgac
      841 gaataaacgc caaaccgcat aatctgtaag ataataatag tcataatgac aaaaatacct
      901 gtaaaaaccg caaaaaaatg aaaaaagtgg tt
//
LOCUS       DATWVB010000112          814 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.113, whole genome shotgun sequence.
ACCESSION   DATWVB010000112 DATWVB010000000
VERSION     DATWVB010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..814
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.113"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..533
                     /locus_tag="VCX65_001796"
     CDS             <1..533
                     /locus_tag="VCX65_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEP5054211.1"
                     /translation="SISVFEGYFNSLISYTRMLSEDRSVKLILVEKLLSELHFEVDDL
                     LNINNIEFSICNRLIITSFYGDEENLIRALSNLLVNAIRFMPVLDKKIEVILSESGEQ
                     IHFEIWNNGERFSDSTLKKGDKLFYTEDYSRGNKHYGIGLAFVKGVAIKHGGNLQLNN
                     PARGGASAIISIKKKI"
     gene            690..>814
                     /locus_tag="VCX65_001797"
     CDS             690..>814
                     /locus_tag="VCX65_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HEP5054212.1"
                     /translation="MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFT"
BASE COUNT          284 a          104 c          153 g          273 t
ORIGIN      
        1 atagtatttc tgtttttgaa ggctatttca attctttaat atcttataca cgcatgcttt
       61 cagaggatag atcagtgaaa ctaattttag ttgagaagct attaagtgag ttacattttg
      121 aagtcgatga cttattgaat atcaataata ttgaattttc tatttgtaat agacttatta
      181 tcacttcttt ttatggagat gaggaaaatc tgataagagc tctttctaac cttttagtta
      241 atgcaataag atttatgccc gtattagata aaaaaatcga agttatactg tctgagtcag
      301 gagagcaaat tcattttgaa atatggaata atggtgagcg tttcagtgat agtacactga
      361 aaaagggaga taaattattt tacacggaag attatagcag aggtaacaaa cattatggaa
      421 tcggtttggc atttgttaaa ggcgttgcta tcaaacacgg tgggaatctt caattgaata
      481 atccagctag aggaggtgct agcgccataa tctcgataaa aaagaaaatt taatagattt
      541 gattgaaact ggagtatttc aggcaaaaaa tcgtaaattt ttgtgatttt tggctaaaat
      601 actttttttc tgaacaaatt ctgaacttgg ggtgtcataa taatcatgta aatatatcgg
      661 atgcaaaaac gtaagagagg aactagaaaa tgaataacac aattaaagac tttgatctcg
      721 atttgaaaac aaataaaaaa gacactgcta caccttatgt tggtagccgt tacctatgta
      781 cccctggttc ttgttggaaa ttagtttgct ttac
//
LOCUS       DATWVB010000113          793 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.114, whole genome shotgun sequence.
ACCESSION   DATWVB010000113 DATWVB010000000
VERSION     DATWVB010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..793
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.114"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            44..>793
                     /gene="mf2"
                     /locus_tag="VCX65_001798"
     CDS             44..>793
                     /gene="mf2"
                     /locus_tag="VCX65_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNase Mf2"
                     /protein_id="HEP5054213.1"
                     /translation="MKLSKQKASLLTAVLLLLSLSITTITVDAAKVRTYPNVSHANTH
                     YKNTASSKLLPFTANYQLQLGELDNLNRATFSHIQLQDRHETKDVRTKINYDPVGWHN
                     YQFPYGDGSKSSWVMNRGHLVGYQFCGLNDEPRNLVTMTAWLNTGAYSGANDSNPEGM
                     LYYENRLDSWLALHPDFWLDYKVTPIYSGNEVVPRQIELQYVGIDSSGELLTIRLNSN
                     KESIDENGVTTVILENSAPNINLDYLNGTATP"
BASE COUNT          264 a          148 c          143 g          238 t
ORIGIN      
        1 gatccactct aaaagctaaa aatggaaagg tttaggtgtt atcatgaaat tatctaaaca
       61 aaaggcaagt ttgcttaccg ctgttttact gttactttct ctttctataa cgacaataac
      121 tgttgacgca gctaaggtac gaacttatcc gaatgtatcc catgcaaaca cacattataa
      181 aaatactgct tctagtaagc tcttaccttt tactgctaat tatcagttac aacttggtga
      241 gttggataac cttaaccgcg ctaccttttc acatatccaa ctgcaagata gacacgaaac
      301 taaagatgta cgcactaaaa taaattatga ccctgtggga tggcataact atcaatttcc
      361 atacggagat ggctcaaaat cttcatgggt aatgaatcgt gggcatctag tcggatatca
      421 attttgtgga ttaaacgatg aaccaagaaa tttagtgaca atgacagcct ggctaaacac
      481 aggtgcttat tcaggagcaa atgacagcaa tcctgaaggg atgttatact atgaaaaccg
      541 tttagattct tggcttgcac ttcaccctga cttttggcta gattataaag tcactcctat
      601 atatagtggc aatgaagtag tgcctcgaca aattgaatta cagtatgttg gaattgattc
      661 atctggtgag ttgcttacta taaggctaaa tagtaataaa gaaagtattg atgaaaatgg
      721 tgttactaca gtaatcttag aaaactctgc tccaaatatc aaccttgact atttaaatgg
      781 aactgccact cct
//
LOCUS       DATWVB010000114          691 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.115, whole genome shotgun sequence.
ACCESSION   DATWVB010000114 DATWVB010000000
VERSION     DATWVB010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..691
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.115"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>691
                     /locus_tag="VCX65_001799"
     CDS             <1..>691
                     /locus_tag="VCX65_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1-like element IS1548 family transposase"
                     /protein_id="HEP5054214.1"
                     /translation="FLVFVCQLAGIETWKEMEDFIEMNEPLFATYVDLSEGCPSHDTL
                     ERVISLVNTDRLKELKVQFEQSLTSLDAVHQLISVDGKTIRGNRGKNQKPVHIVTAYD
                     GGHHLSLGQVAVEEKSNEIVAIPQLLRTIDIRKSIVTIDAMGTQTAIVDTIIKGKADY
                     CLAVKGNQETLYDDIALYFSDVNLLEELQENAQYYQTVEKSRGQIEVREYWVSSDIKW
                     LCQNHPKWHKLR"
BASE COUNT          216 a          108 c          161 g          206 t
ORIGIN      
        1 tatttcttgt cttcgtttgt cagttagctg gcattgaaac ctggaaggag atggaagatt
       61 ttattgaaat gaatgaacca ttgtttgcga cctacgttga tttgagtgaa ggttgtccgt
      121 ctcatgatac cttagagcgt gtgattagtc ttgttaatac agaccgttta aaagagctta
      181 aagttcaatt tgagcaatca ttgacaagct tagatgccgt tcatcaactg atttcagtgg
      241 acggtaaaac gattcgaggc aatcgaggta aaaatcagaa gcctgttcat attgtaacgg
      301 cttatgatgg gggtcatcat cttagtttgg gacaggtagc ggttgaggag aaaagtaatg
      361 aaattgttgc cattcctcag ttattgcgga caattgatat ccgtaaaagc attgtaacga
      421 tagacgcaat gggcacgcag acggctatcg ttgatacgat tataaaaggt aaagcagact
      481 attgcttagc cgtcaaagga aatcaagaaa cactttatga tgatattgct ctttatttta
      541 gtgatgtcaa cttattggaa gaactccaag aaaatgcaca gtattatcag actgttgaaa
      601 aatctagggg acagattgaa gttagagaat actgggtgtc ttccgatatc aaatggttgt
      661 gtcaaaacca tcccaaatgg cataagttac g
//
LOCUS       DATWVB010000115          574 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.116, whole genome shotgun sequence.
ACCESSION   DATWVB010000115 DATWVB010000000
VERSION     DATWVB010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..574
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.116"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>574
                     /locus_tag="VCX65_001800"
     CDS             <1..>574
                     /locus_tag="VCX65_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP5054215.1"
                     /translation="INAMQKVTSEEELNGTNLFYWLVTISRVDTESPIILANLEKNID
                     VRKREIEHGDNEGLVVDTRLLFDPFRQILVVYNQRGTINNYDLRRFFCQIIGVRGLKF
                     DIILNSDAFKRVGKLDVVNSISYTVASPTNFKEFRDDTQSENADLKFANSMLGESMQV
                     VIKSNHLSKKNIFDKFSDMLVNDSVNVKNAK"
BASE COUNT          214 a           60 c          111 g          189 t
ORIGIN      
        1 tataaatgca atgcagaagg taacaagtga agaagaatta aatggaacga atctatttta
       61 ttggttagtt accatttcac gggtggatac agaatctcca attattcttg cgaatcttga
      121 aaaaaatatt gatgtaagaa aaagggaaat tgaacatggg gataatgagg gccttgtggt
      181 tgatacaaga ttattatttg acccatttag acaaatttta gttgtttata atcaaagagg
      241 tacaattaat aattacgact taagaaggtt tttttgtcaa ataattggag ttagaggatt
      301 gaagtttgat attatattaa acagtgatgc tttcaaaagg gttggtaagc ttgatgttgt
      361 aaattcaatt agttatactg ttgcaagccc aacaaacttt aaggagtttc gagatgatac
      421 tcaaagtgaa aatgccgatt taaagtttgc aaattctatg ctaggagagt caatgcaggt
      481 tgttataaag tcaaaccatc tttctaaaaa aaatatattt gataaatttt cagatatgtt
      541 agttaatgac tcagttaatg taaaaaatgc taaa
//
LOCUS       DATWVB010000116          559 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.117, whole genome shotgun sequence.
ACCESSION   DATWVB010000116 DATWVB010000000
VERSION     DATWVB010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..559
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.117"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..126
                     /locus_tag="VCX65_001801"
     CDS             <1..126
                     /locus_tag="VCX65_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEP5054216.1"
                     /translation="KINLYDAKPNSTRSDVLKKYKDNKTINMKDFSHFDIYLWTK"
     gene            306..539
                     /locus_tag="VCX65_001802"
                     /pseudo
     CDS             306..539
                     /locus_tag="VCX65_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          222 a           93 c           85 g          159 t
ORIGIN      
        1 aaaatcaatt tatatgacgc aaaacccaat agcaccagat ctgatgtctt aaaaaaatat
       61 aaagacaata agactataaa catgaaagat ttcagccatt ttgatattta tctttggact
      121 aaataagcta aaagctctgg ataaatatga tcaattgacc tataataaca ttgataccaa
      181 atctaaaact gctcagattg aattgcgccc caaaagttag acaaaaaatc taataattgg
      241 ggtgtttttg tctggcatta agtttagcta ataaccttgc ttaaatcaca ttaaaccaat
      301 aatggaaaaa ggcatctcca aataaatgct atgacggaac tatatgatag agtgatcaag
      361 gttggcaata tcaacacaac tattatcatc atttcctaaa ctctaaagga attcgtccgt
      421 ctatgtcacg taaaagaaac aggcctgaca atggcatgat ggaatctttc tttggcatct
      481 taaaatcaga aatgttctat ggttatgaga ataactgtaa atcactagaa gactcagaat
      541 aagcgattac aaatgacat
//
LOCUS       DATWVB010000117          452 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.118, whole genome shotgun sequence.
ACCESSION   DATWVB010000117 DATWVB010000000
VERSION     DATWVB010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.118"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            <1..>452
                     /locus_tag="VCX65_001803"
     CDS             <1..>452
                     /locus_tag="VCX65_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEP5054217.1"
                     /translation="HVEKIKKYIEQKYKNISFSIDYHYYLTTTGSCIDFGEEGAVGRG
                     NKTHGIISSFRPNTMEAPAGKNCTYFVGKVWGFLSDTIAKEIYEAFNTPCQIIMQLNI
                     GSKLYRPTHLFIQTEESVDQERVLEIVNRHLNNGKQNTNLILSTQHFI"
BASE COUNT          174 a           58 c           73 g          147 t
ORIGIN      
        1 aacacgtaga aaaaattaag aaatatattg aacaaaagta taaaaacata agcttttcta
       61 ttgattacca ttattattta actactacag gttcttgtat tgatttcgga gaagaaggtg
      121 cagttggtcg aggtaataaa actcatggta tcatatcaag ttttaggcca aatactatgg
      181 aagcaccagc tggaaaaaat tgtacttatt ttgtaggaaa ggtttgggga tttttgtctg
      241 atactattgc caaagaaatt tatgaagcat tcaatactcc ctgtcaaatc attatgcaat
      301 taaatattgg atcaaaattg tatagaccaa cccatttatt tattcagaca gaagaaagtg
      361 ttgatcaaga aagagtatta gaaattgtta acaggcattt aaataatggt aaacaaaata
      421 ctaatttaat cttgtcaact caacatttta tt
//
LOCUS       DATWVB010000118          434 bp    DNA     linear   BCT 28-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes strain MGAS28713
            SAMN08562509-rid19685163.denovo.119, whole genome shotgun sequence.
ACCESSION   DATWVB010000118 DATWVB010000000
VERSION     DATWVB010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN08562509
            Sequence Read Archive: SRR6746843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001919187.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001919187.2
            Genome Coverage       :: 256x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/12/2023 14:51:48
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,804
            CDSs (total)                      :: 1,764
            Genes (coding)                    :: 1,716
            CDSs (with protein)               :: 1,716
            Genes (RNA)                       :: 40
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 29 of 48
            Pseudo Genes (incomplete)         :: 22 of 48
            Pseudo Genes (internal stop)      :: 9 of 48
            Pseudo Genes (multiple problems)  :: 11 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN08562509-rid19685163.denovo.119"
                     /strain="MGAS28713"
                     /serotype="Emm28"
                     /isolation_source="normally sterile site"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: Minnesota"
                     /collection_date="2011"
                     /collected_by="CDC Active Bacterial Core Surveillance"
     gene            complement(<1..>434)
                     /locus_tag="VCX65_001804"
     CDS             complement(<1..>434)
                     /locus_tag="VCX65_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEP5054218.1"
                     /translation="NKAIDQVVFGIDAKANGVDNAEYGNSIMTVTTQPDGSFVFKHDM
                     IDGVKTIGHGTLTGKINHHYEANKDGSITAYIDSVTFDKYEYQNVAKNDAVDKNIAFR
                     ILSATGQELFVKAHDGDKTFSETLNKTVSLKLTYQLKPHEAV"
BASE COUNT          137 a           84 c           58 g          155 t
ORIGIN      
        1 tacagcttca tgcggtttta gttggtaagt taacttaaga gacactgtct tatttaaagt
       61 ttcactaaaa gttttatcac catcatgggc tttaacaaat aattcttgac ctgtggcact
      121 taaaatacga aaagcaatat ttttatcaac tgcgtcattt ttagctacat tttgatattc
      181 atacttatca aatgttacac tatcaatata agctgtaatg ctaccatctt tattagcctc
      241 ataatgatga ttaattttac ccgttaaagt cccatgacca attgttttga caccatcaat
      301 catatcatgc ttaaaaacaa acgaaccatc tggttgcgtt gtaacagtca tgattgaatt
      361 accatattct gcattatcaa caccgttggc ttttgcatca attccaaaga caacctgatc
      421 gatagctttg tttt
//
