LOCUS       DAUCXI010000001        84221 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.001, whole genome shotgun sequence.
ACCESSION   DAUCXI010000001 DAUCXI010000000
VERSION     DAUCXI010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84221
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.001"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..820)
                     /locus_tag="VGY43_000001"
     CDS             complement(<1..820)
                     /locus_tag="VGY43_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ4301230.1"
                     /translation="MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCH
                     YQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWSGQLTAYQEII
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIR"
     gene            876..1508
                     /locus_tag="VGY43_000002"
     CDS             876..1508
                     /locus_tag="VGY43_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEQ4301231.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNRQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            1636..2577
                     /gene="cysK"
                     /locus_tag="VGY43_000003"
     CDS             1636..2577
                     /gene="cysK"
                     /locus_tag="VGY43_000003"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEQ4301232.1"
                     /translation="MTKIYKTITELVDQTPIIKLNRLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAEAEGMISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKASPETVIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(2595..2972)
                     /locus_tag="VGY43_000004"
     CDS             complement(2595..2972)
                     /locus_tag="VGY43_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ4301233.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALDNGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKPSLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(2972..4372)
                     /locus_tag="VGY43_000005"
     CDS             complement(2972..4372)
                     /locus_tag="VGY43_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEQ4301234.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPLLQEKADFITKKVEEDGILYALEELGLIDKELQFPQL
                     DLPNHKGPKATIKTNHGDMTLVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPAPIAASYAANGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            complement(4409..5050)
                     /locus_tag="VGY43_000006"
     CDS             complement(4409..5050)
                     /locus_tag="VGY43_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4301235.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNFQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN"
     gene            complement(5043..6047)
                     /locus_tag="VGY43_000007"
     CDS             complement(5043..6047)
                     /locus_tag="VGY43_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ4301236.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            complement(6044..6736)
                     /locus_tag="VGY43_000008"
     CDS             complement(6044..6736)
                     /locus_tag="VGY43_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEQ4301237.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            complement(6859..8766)
                     /gene="pknB"
                     /locus_tag="VGY43_000009"
     CDS             complement(6859..8766)
                     /gene="pknB"
                     /locus_tag="VGY43_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEQ4301238.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQMPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIIFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTNQTDALQ
                     PPTKKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQEL
                     YDVGLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKG
                     LDYQEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLS
                     VAVSDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAI
                     VSGQSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSTNDSTAPGSNTE
                     LSPSETTAQTP"
     gene            complement(8763..9503)
                     /locus_tag="VGY43_000010"
     CDS             complement(8763..9503)
                     /locus_tag="VGY43_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEQ4301239.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            complement(9541..10863)
                     /gene="rsmB"
                     /locus_tag="VGY43_000011"
     CDS             complement(9541..10863)
                     /gene="rsmB"
                     /locus_tag="VGY43_000011"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEQ4301240.1"
                     /translation="MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLIYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSHRAVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADTVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            complement(10853..11788)
                     /locus_tag="VGY43_000012"
     CDS             complement(10853..11788)
                     /locus_tag="VGY43_000012"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEQ4301241.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFGQFLPTLLLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSN
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIATGQGA
                     LSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR"
     gene            complement(11850..14234)
                     /locus_tag="VGY43_000013"
     CDS             complement(11850..14234)
                     /locus_tag="VGY43_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEQ4301242.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFVIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKPDRDFLFEGKPSVLYSTLDREKEKIALKAIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERQIDRSESYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTQRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECHSNSIRYYGTGTQKAFDELQGVI
                     PEARILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKKQDFEAFY
                     RYEMAIRRQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSLLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            complement(14299..14616)
                     /locus_tag="VGY43_000014"
     CDS             complement(14299..14616)
                     /locus_tag="VGY43_000014"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEQ4301243.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(14632..15267)
                     /gene="gmk"
                     /locus_tag="VGY43_000015"
     CDS             complement(14632..15267)
                     /gene="gmk"
                     /locus_tag="VGY43_000015"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEQ4301244.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK"
     gene            complement(15377..16984)
                     /locus_tag="VGY43_000016"
     CDS             complement(15377..16984)
                     /locus_tag="VGY43_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEQ4301245.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            complement(17158..18102)
                     /locus_tag="VGY43_000017"
     CDS             complement(17158..18102)
                     /locus_tag="VGY43_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ4301246.1"
                     /translation="MIDLAIAIKNHLCHNGINTIGKKTNRQGDNHLDIKQIRYFIAIV
                     ENHFNLSQAAELLYVSQPTLSMMINDFEKRENVKLFKRKRGRIIGLTYLGDNYYKDAQ
                     KVLSLYDDMFLKLHDHSKGLKGSINIGIPPLILSVVFSEVMPKLILENPGIQFNVKEI
                     GAYQLKNELLVGNVDVAVLLSPTGIADNLVETYEIQRSELSVCLSPRHRLASKKVIQW
                     EDLTDEQLALFDPSFMVHHLVLEACERHQVRPNIILTSSSWDFMLNSTKINHNVLTIC
                     PKPITELYQLKDIKCIPMERPISWRVVLTRLRKKVILK"
     gene            18208..19395
                     /locus_tag="VGY43_000018"
     CDS             18208..19395
                     /locus_tag="VGY43_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ4301247.1"
                     /translation="MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQIAIHSGIPSDKTAFTLDMVCGSGLKAIQLATQSI
                     MLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGAGPIPATQKVLKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            19419..20069
                     /locus_tag="VGY43_000019"
     CDS             19419..20069
                     /locus_tag="VGY43_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ4301248.1"
                     /translation="MCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVK
                     DLTLICNDAGFPDKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTL
                     AERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLEKPLKADIALIFANKADK
                     NGNLQYAGSENNFNHVMAANAKTTIVEAREVVDVGQMDPNFVHTPGIFVNYLVKGA"
     gene            20071..20730
                     /locus_tag="VGY43_000020"
     CDS             20071..20730
                     /locus_tag="VGY43_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ4301249.1"
                     /translation="MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPSIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINQDYTFEDVQNVTEVTLIDKT
                     N"
     gene            20763..21542
                     /locus_tag="VGY43_000021"
     CDS             20763..21542
                     /locus_tag="VGY43_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEQ4301250.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYTAQ"
     gene            21613..22944
                     /locus_tag="VGY43_000022"
     CDS             21613..22944
                     /locus_tag="VGY43_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEQ4301251.1"
                     /translation="MEIIGSLGVLVGVIVIIYLSVKEVNIIIAAPLATSLVIWFNQMD
                     PTTTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGATTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVTFGLFYMKYCLAKSMARG
                     ETYTTYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     AILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIAPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIMIAFDLFS"
     gene            23018..23500
                     /locus_tag="VGY43_000023"
     CDS             23018..23500
                     /locus_tag="VGY43_000023"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEQ4301252.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(23645..25114)
                     /locus_tag="VGY43_000024"
     CDS             complement(23645..25114)
                     /locus_tag="VGY43_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301253.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERVIPEPQMTKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLGILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSAKKAMRLKAAAKAFEKQYGTFYTDATKSKLKNSAFATLPDLEAALKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDAVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQEAQDQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGNQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(25128..26282)
                     /locus_tag="VGY43_000025"
     CDS             complement(25128..26282)
                     /locus_tag="VGY43_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEQ4301254.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWGNYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKVNGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            complement(26345..26713)
                     /gene="rnpB"
                     /locus_tag="VGY43_000026"
     ncRNA           complement(26345..26713)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VGY43_000026"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(26727..27053)
                     /gene="gpsB"
                     /locus_tag="VGY43_000027"
     CDS             complement(26727..27053)
                     /gene="gpsB"
                     /locus_tag="VGY43_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEQ4301255.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            complement(27172..27687)
                     /locus_tag="VGY43_000028"
     CDS             complement(27172..27687)
                     /locus_tag="VGY43_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEQ4301256.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDKWNEKNQEVLSQFRAVDF
                     VKYYFPNYEQPPQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPYYQLLLL
                     TFDRLNDMSQS"
     gene            27768..28376
                     /gene="recU"
                     /locus_tag="VGY43_000029"
     CDS             27768..28376
                     /gene="recU"
                     /locus_tag="VGY43_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEQ4301257.1"
                     /translation="MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDY
                     YLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAK
                     ETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQID
                     NGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            28363..30528
                     /locus_tag="VGY43_000030"
     CDS             28363..30528
                     /locus_tag="VGY43_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ4301258.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLRSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKNRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDISNSTNTDNNSNHPSTDDKKTTH"
     gene            complement(30993..32330)
                     /gene="pepC"
                     /locus_tag="VGY43_000031"
     CDS             complement(30993..32330)
                     /gene="pepC"
                     /locus_tag="VGY43_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEQ4301259.1"
                     /translation="MSALTETFTEQLFAHYEASAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGAKADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQC"
     gene            complement(32515..33339)
                     /gene="nadE"
                     /locus_tag="VGY43_000032"
     CDS             complement(32515..33339)
                     /gene="nadE"
                     /locus_tag="VGY43_000032"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEQ4301260.1"
                     /translation="MTLQEEIIRQLGVKASIAPQEEIRKTVDFLKAYLRKHLFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREETSDQAYQFIAVRLPYGVQADEADAQKALAFIM
                     PDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            complement(33336..34796)
                     /locus_tag="VGY43_000033"
     CDS             complement(33336..34796)
                     /locus_tag="VGY43_000033"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEQ4301261.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPENFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAIIGGADATSNVRAGKRFGIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVSTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVRNFDAIPLLVDIFVKGELVYQLPTLSEIKTYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMALIDNIRKDTHGKSDLK"
     gene            complement(34966..36345)
                     /locus_tag="VGY43_000034"
     CDS             complement(34966..36345)
                     /locus_tag="VGY43_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ4301262.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNSLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            complement(36514..37431)
                     /gene="trxB"
                     /locus_tag="VGY43_000035"
     CDS             complement(36514..37431)
                     /gene="trxB"
                     /locus_tag="VGY43_000035"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEQ4301263.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVSTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIKGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMIPVTGMVTDLEITDQEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFPS"
     gene            complement(37495..37719)
                     /locus_tag="VGY43_000036"
     CDS             complement(37495..37719)
                     /locus_tag="VGY43_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEQ4301264.1"
                     /translation="MLVEIFSLYVKGLILSSLTMMLICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            complement(37823..38566)
                     /locus_tag="VGY43_000037"
     CDS             complement(37823..38566)
                     /locus_tag="VGY43_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301265.1"
                     /translation="MITIRNLSKTFSEQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQEFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            complement(38566..39369)
                     /locus_tag="VGY43_000038"
     CDS             complement(38566..39369)
                     /locus_tag="VGY43_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ4301266.1"
                     /translation="MTSVFLTSGWAFYDHLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKCLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            complement(39564..40907)
                     /locus_tag="VGY43_000039"
     CDS             complement(39564..40907)
                     /locus_tag="VGY43_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ4301267.1"
                     /translation="MSFKDYHFKQYVQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHSQEEIRL
                     ANYVGGTDKLRQIEKLKGGQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF"
     gene            complement(41065..42075)
                     /locus_tag="VGY43_000040"
     CDS             complement(41065..42075)
                     /locus_tag="VGY43_000040"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEQ4301268.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFC
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            complement(42077..44332)
                     /locus_tag="VGY43_000041"
     CDS             complement(42077..44332)
                     /locus_tag="VGY43_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ4301269.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            complement(44336..44659)
                     /gene="ftsL"
                     /locus_tag="VGY43_000042"
     CDS             complement(44336..44659)
                     /gene="ftsL"
                     /locus_tag="VGY43_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEQ4301270.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            complement(44664..45677)
                     /gene="rsmH"
                     /locus_tag="VGY43_000043"
     CDS             complement(44664..45677)
                     /gene="rsmH"
                     /locus_tag="VGY43_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEQ4301271.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            complement(45701..45865)
                     /locus_tag="VGY43_000044"
     CDS             complement(45701..45865)
                     /locus_tag="VGY43_000044"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301272.1"
                     /translation="MSWDKTFGIWLDNLLTDWCVIKEAKNLLQAVEILEAAAKSVLAK
                     LADSEQKEQD"
     gene            complement(45908..46123)
                     /locus_tag="VGY43_000045"
     CDS             complement(45908..46123)
                     /locus_tag="VGY43_000045"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301273.1"
                     /translation="MTNEREKEEAKVALEELLHQIQVIHLELKIVRNWGYFVFLETVC
                     LSAGSNVVSKVKQLLIDLQVTLQNCRR"
     gene            complement(46143..47393)
                     /locus_tag="VGY43_000046"
     CDS             complement(46143..47393)
                     /locus_tag="VGY43_000046"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEQ4301274.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGARLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDMATKIVINAKTRRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQ
                     HTSYHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            complement(47386..48207)
                     /gene="proB"
                     /locus_tag="VGY43_000047"
     CDS             complement(47386..48207)
                     /gene="proB"
                     /locus_tag="VGY43_000047"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEQ4301275.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVITQEIIASAGGAGSKF
                     GTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD"
     gene            complement(48272..49900)
                     /locus_tag="VGY43_000048"
     CDS             complement(48272..49900)
                     /locus_tag="VGY43_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4301276.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQEKHPKENFKAYKSMM
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGAVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MTDGVFTDYPTIPYFKGFYDVVQAPFSTVALLNFWFPLLLILAMVYGIVTKVMPTYYR
                     EVFYISNENKVKQTKKPVNRPHQNQSLAQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGVMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLLDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTIAFCLGYALSLIVQG
                     ELMYRRDYRLLDIKWQDMTQLFTRGDGQWLTMGLIFGNLIVAGVLGFGAVIIANIIQQ
                     PLLISILLSCLILMVLGLAQLWIQKTFWKSLERL"
     gene            complement(49905..50639)
                     /locus_tag="VGY43_000049"
     CDS             complement(49905..50639)
                     /locus_tag="VGY43_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301277.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            complement(50673..50939)
                     /locus_tag="VGY43_000050"
     CDS             complement(50673..50939)
                     /locus_tag="VGY43_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ4301278.1"
                     /translation="MEKKRQRLYDVIRHAYDYPENRENVALSQLLLAASNRLIKHSNP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASSV"
     gene            complement(51131..53116)
                     /gene="tkt"
                     /locus_tag="VGY43_000051"
     CDS             complement(51131..53116)
                     /gene="tkt"
                     /locus_tag="VGY43_000051"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEQ4301279.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQKAF
                     TNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNTAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            complement(53335..53979)
                     /gene="fsa"
                     /locus_tag="VGY43_000052"
     CDS             complement(53335..53979)
                     /gene="fsa"
                     /locus_tag="VGY43_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ4301280.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            complement(54105..55604)
                     /locus_tag="VGY43_000053"
     CDS             complement(54105..55604)
                     /locus_tag="VGY43_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ4301281.1"
                     /translation="MKIEDLMDKERKAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYFEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMGQETDFSQQLSDDILVLLIFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVCLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            complement(55594..56940)
                     /locus_tag="VGY43_000054"
     CDS             complement(55594..56940)
                     /locus_tag="VGY43_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ4301282.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNYRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFGYYRASVGVTEEEAELYMDTCSYLYQNGNSKNLFWLKLIARKTDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDGDLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            complement(57049..57750)
                     /locus_tag="VGY43_000055"
     CDS             complement(57049..57750)
                     /locus_tag="VGY43_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ4301283.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAVFISGKVAPAHLNPAVSLAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAALAVLLFQVMS"
     gene            complement(57761..59590)
                     /gene="glpO"
                     /locus_tag="VGY43_000056"
     CDS             complement(57761..59590)
                     /gene="glpO"
                     /locus_tag="VGY43_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEQ4301284.1"
                     /translation="MEFSKEIRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANRDGALIASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQT
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIDPVIKEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGQ"
     gene            complement(59606..61132)
                     /gene="glpK"
                     /locus_tag="VGY43_000057"
     CDS             complement(59606..61132)
                     /gene="glpK"
                     /locus_tag="VGY43_000057"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEQ4301285.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     INTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDTK
                     "
     gene            complement(61493..61885)
                     /locus_tag="VGY43_000058"
     CDS             complement(61493..61885)
                     /locus_tag="VGY43_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEQ4301286.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSKKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            complement(62012..62269)
                     /locus_tag="VGY43_000059"
     CDS             complement(62012..62269)
                     /locus_tag="VGY43_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEQ4301287.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            complement(62423..64462)
                     /locus_tag="VGY43_000060"
     CDS             complement(62423..64462)
                     /locus_tag="VGY43_000060"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEQ4301288.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENHLSFEDI
                     QTFSTPRRLAVRVSGLAAQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPVSMHWANNSFEYIRPVH
                     TLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQFVIADAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGSFEAKYLDVPEEVLITS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEDAAVARAIREHYLPDAAGGALPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYD
                     LSFDSLTYANKADVMNFIRARVDKMMGKATPKDIREAVLESSTFVVPEMLAAAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQ
                     QLEQVFALSPVINDFFDNTMVMAEDQALKNNRVAILSDLVSKAKTIAAFNQLNTK"
     gene            complement(64839..65756)
                     /gene="glyQ"
                     /locus_tag="VGY43_000061"
     CDS             complement(64839..65756)
                     /gene="glyQ"
                     /locus_tag="VGY43_000061"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEQ4301289.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEMSDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDGE"
     gene            complement(66127..66660)
                     /locus_tag="VGY43_000062"
     CDS             complement(66127..66660)
                     /locus_tag="VGY43_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEQ4301290.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            complement(66792..67631)
                     /locus_tag="VGY43_000063"
     CDS             complement(66792..67631)
                     /locus_tag="VGY43_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEQ4301291.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLGRLGLAYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVYHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTPEDKKTIRYLSGMSAIPNPDT
                     TSF"
     gene            complement(67753..68901)
                     /gene="nagA"
                     /locus_tag="VGY43_000064"
     CDS             complement(67753..68901)
                     /gene="nagA"
                     /locus_tag="VGY43_000064"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEQ4301292.1"
                     /translation="MTCYLKADCFYYPTEVKPAGYLSLHDGVFGEWTEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKNPRLEEFDAWQKAAK
                     GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLIHREPGMVGAVYNLPNTYAELICDGHHVSPIACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVAWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            complement(69019..70650)
                     /locus_tag="VGY43_000065"
     CDS             complement(69019..70650)
                     /locus_tag="VGY43_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEQ4301293.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADDKFGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            70852..71574
                     /locus_tag="VGY43_000066"
     CDS             70852..71574
                     /locus_tag="VGY43_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301294.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSHP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILL
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            complement(71703..72545)
                     /locus_tag="VGY43_000067"
     CDS             complement(71703..72545)
                     /locus_tag="VGY43_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ4301295.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYAGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            72838..73395
                     /locus_tag="VGY43_000068"
     CDS             72838..73395
                     /locus_tag="VGY43_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ4301296.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            complement(73432..74256)
                     /locus_tag="VGY43_000069"
     CDS             complement(73432..74256)
                     /locus_tag="VGY43_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ4301297.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD"
     gene            complement(74258..74875)
                     /locus_tag="VGY43_000070"
     CDS             complement(74258..74875)
                     /locus_tag="VGY43_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEQ4301298.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLIARGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            complement(75072..76049)
                     /gene="lacD"
                     /locus_tag="VGY43_000071"
     CDS             complement(75072..76049)
                     /gene="lacD"
                     /locus_tag="VGY43_000071"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ4301299.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            complement(76096..76549)
                     /locus_tag="VGY43_000072"
                     /pseudo
     CDS             complement(76096..76549)
                     /locus_tag="VGY43_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP;
                     frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            complement(76559..77074)
                     /gene="lacB"
                     /locus_tag="VGY43_000073"
     CDS             complement(76559..77074)
                     /gene="lacB"
                     /locus_tag="VGY43_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ4301300.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLETHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            complement(77089..77514)
                     /gene="lacA"
                     /locus_tag="VGY43_000074"
     CDS             complement(77089..77514)
                     /gene="lacA"
                     /locus_tag="VGY43_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ4301301.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            complement(77771..79222)
                     /locus_tag="VGY43_000075"
     CDS             complement(77771..79222)
                     /locus_tag="VGY43_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEQ4301302.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYADHNHLPVLVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGSQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFSVESVKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIESVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMK"
     gene            complement(79248..79553)
                     /locus_tag="VGY43_000076"
     CDS             complement(79248..79553)
                     /locus_tag="VGY43_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ4301303.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFEMPIPTVEAGPILYRIPIMSEPVFAELERVIKENHLQ"
     gene            complement(79546..80019)
                     /locus_tag="VGY43_000077"
     CDS             complement(79546..80019)
                     /locus_tag="VGY43_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ4301304.1"
                     /translation="MFPNILFTEARTQPELFDLVASHLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTTILSNLITFFITKGNLSCLASLKDDKQAISNYLIEKGVFQHD"
     gene            80256..81026
                     /locus_tag="VGY43_000078"
     CDS             80256..81026
                     /locus_tag="VGY43_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ4301305.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYSQFTQLLVAHENKE"
     gene            complement(81230..81433)
                     /locus_tag="VGY43_000079"
     CDS             complement(81230..81433)
                     /locus_tag="VGY43_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEQ4301306.1"
                     /translation="MEKHYQVTGMTCDGCARTVTEKLSAVPGVQSVQVNLEKGEAKVT
                     GRPLTFLLKRALKDTKFELHKWS"
     gene            complement(81447..83678)
                     /locus_tag="VGY43_000080"
     CDS             complement(81447..83678)
                     /locus_tag="VGY43_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEQ4301307.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKTVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPSFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGHP
                     NMDSLVALATSFAFAYSLYGVVEISLGRAHFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTYQAIQKLLSLKATDVRVWRNSQWQLLPLEEISYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGQGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIAAIADRVSGVFVPVVLVLALLTGVFWLVFIQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTITEGKPSLQNLLT
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNATLMATLGIDLASVQSVCAKASGKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALQQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVITNLQSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRATM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            complement(83678..84112)
                     /locus_tag="VGY43_000081"
     CDS             complement(83678..84112)
                     /locus_tag="VGY43_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEQ4301308.1"
                     /translation="MQQISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTL
                     IGRLVKKNLLTSYREGRAYIYQALLDETLLQKEALATVLDGICQRQHTRLLLERLYDL
                     PMTLEEIEAFQELLEVKKENAVLEVPCNCLPGQCHCQKKETY"
BASE COUNT        25317 a        17985 c        15118 g        25801 t
ORIGIN      
        1 ttcttataaa ttttggaata actaatggcc tattatgaaa gcgtctcgcc aatgtcagct
       61 tgactacttc tcccttgttt acctttcttt ctaaagttct agttgaagtt gcagttaata
      121 aaatctttgc gccaccttct tttaaagcct gacttgcagc ataatgaagt tgaatattat
      181 ttacaaaagg gaatgcgtct acttcatcaa taattaagag atcaaaagcc ttgtgaaatt
      241 ttagcagctg atgcgttgtg gctactataa taggagctct ttgataagga agagactctg
      301 cgtgcattaa acagatgctg caggagaagg cttgggataa acgagtagcc acctctacac
      361 aaacatctac tcttgggctg gcaatgcaaa cccagccacc tgtgttaatt accgcctcaa
      421 tcgcagcata aatcatttct gtttttcctg caccagttac agcatgaact aatgttgttt
      481 tttgattttg catattgatt aataattgtt gggaaattat ctcttgataa gcagttagtt
      541 gaccgctcca aaccagataa ttaccttttg gaaaatgcat aggtgggata gcatagagca
      601 atttatctga ttgatttcgt ccaaagacaa gacaaaatcg gcaataatag gctccacttg
      661 gcaatcgtgc ttcttcatca agctgatagt gacaacgttg acaaatcatt tttcctctca
      721 atattactac actttttaaa ggttgagcaa gctgctttgc tgaatctggt aactggcttt
      781 ctagcaacaa ccgtccataa ctattttcaa tagactccat actttattat tcgctttttt
      841 ttgctaattt ttatcttttc ttgtacaatt tttttatgga acattttaag acaatcaaag
      901 ccagtggttt tttcgaagaa agtattaaaa aatctcgttt catttgtcat atcaaacgag
      961 tgagcactga agaagatggt aagaattttg ttaatgctat caaaaaagaa cattacaaag
     1021 ctaatcattc ctgctttgcg atgattatcg gtaacaacag acagatcaag cgctcaagtg
     1081 atgatggtga accttcagga actgctggaa tacctatcct ttctgtgtta gaaaagcagt
     1141 gtttaacaaa tgtagtagtt gtggtaacgc gttactttgg tggtattaaa ttaggaacag
     1201 gtgggttaat cagagcatac tctaacatga ccgcaacagc tattaaacga tttggcatca
     1261 ttgaagttaa acagcagata ggactagaaa tcacactttc ttatcctcaa tatcaactat
     1321 actctaactt gctagatcaa ttggctttaa ccgaaacaga aactaagttt tcagacacga
     1381 taaagacaac actttattgt gatactgaac gtgtggaaaa tctcattgat actttaacaa
     1441 attattatca tggtcagata agctgtgaga aaatcggatc caaagttatt gaattcccct
     1501 gtgattaatc atcaacaaaa gtgatatggc tttattatca gagtgatagt aaatctgtat
     1561 tttactttaa taatatctct ccttatactt aaatacacag cgtatttatt ttgtatcaag
     1621 aaaagaggct aaactatgac taaaatttac aaaactataa cagaattagt agatcaaaca
     1681 cctattatca aacttaaccg tttaattcca aacgaagctg ctgacgttta tgtaaaatta
     1741 gaagctttta acccaggatc ttctgttaaa gatcgtattg ctttatcgat gattgaagct
     1801 gctgaagctg aaggtatgat aagtcctggt gacgttatta tcgaaccaac aagtggtaat
     1861 acaggtattg gtcttgcatg ggtaggtgct gctaaagggt atcgagtcat tattgttatg
     1921 cccgaaacta tgagcttgga aagacggcaa atcattcagg cttatggtgc agagcttgtc
     1981 ttaacacctg gagcagaagg tatgaaaggg gctattgcaa aagctgaaac tttagcaata
     2041 gaactaggtg cttggatgcc tatgcaattt aataaccctg ccaatccaag catccatgaa
     2101 aaaacaacag ctcaagaaat tttggaagct tttaaggaga tttctttaga tgcattcgta
     2161 tctggtgttg gtactggagg aacactttct ggtgtttcac atgtcttgaa aaaagctagc
     2221 cctgaaactg ttatctatgc tgttgaagct gaagaatctg ctgtcttatc tggtcaagag
     2281 cctggaccac ataaaattca aggtatatca gctggattta tcccaaacac gttagatacc
     2341 aaagcctatg accaaattat ccgtgttaaa tcgaaagatg ctttagaaac tgctcgacta
     2401 acaggagcta aggaaggctt cctggttggg atttcttctg gagctgctct ttacgccgct
     2461 attgaagtcg ctaaacagtt aggaaaaggc aaacatgtgt taactatttt accagataat
     2521 ggcgaacgct atttatcgac tgaactctat gatgtaccag taattaagac gaaataaaaa
     2581 agggtttgga actactaagg ttccagactc tttttagtgt tcttttttaa aaactgcagg
     2641 ctttcttcaa tccactgagg taactgctct tcaagtggcc taaagccaat cttgtgccga
     2701 ctgttggaat aacgatgacg atggaaaaaa tgctgttttt cttctgctaa ggtccgcata
     2761 gataaacttg gctttttact atattcatca atatcaatta cttgtactaa aacctggttg
     2821 cctatagcca ataattgatc aatatcgtca ataaatcccg tttttatttc tgaaatatga
     2881 atgagacctg ttgtcccatt gtcaagggca acaaaggctc cgtatggttt aatcccagtg
     2941 atggtgccat gcagtttgtc gccaattttc attagtcaaa tacctcgatt gtttcaatga
     3001 taacgtcttc tttaggttta tcctgtgcgc cagtttcaac gccagcaatc aaatccaaaa
     3061 cttggaatga agtttcgtcc acaagctgac caaagaccgt atgacgacga tcaaggtgag
     3121 gagttccacc atttgcagcg taagaagctg caattggagc cggccaacca ccacgttcta
     3181 gttctttttt ggcataagga atcttactat tttgaacaat aaagaactga ctgccgttag
     3241 tatttggtcc cgcattagcc atcgacaagg ccccacggag attatagagt tcatccgaaa
     3301 attcatcttc aaaactttca ccatagatgg attgtccacc cattcctgtt cctgttggat
     3361 cgcccccttg aatcataaat tcaggaataa tacggtggaa gataatccca tcatagtacc
     3421 cttctttagc caaacctaag aaattggcta ctgttttagg agcatgatct gggaacaaga
     3481 ccagggtcat atcgccatgg tttgttttaa tggttgcttt tggtccttta tggtttggca
     3541 aatccaattg tggaaactgt aattctttgt caatcaatcc taattcctcc aaggcatata
     3601 aaatgccatc ttcttcaact ttttttgtga taaaatctgc tttttcttgc agcaatggat
     3661 gtgatactcc cattgcaata ctgataccag catagtcaaa taactctagg tcattgagtt
     3721 catctccaaa aaccaaaatg ttttcaggtt ttaatcctaa atggtcaact acttttgaaa
     3781 cacctagcgc ttttgacgta cctttcaaga caacatctga tgagttatcg tgccatctga
     3841 ccaaacgaag gtgctctgct aattcagcag gcaactgcaa gccatctccc ttgtcctcga
     3901 aagtccacat ctggtaaaca tcatgatact cattataatc cggacagacc tctagttgag
     3961 cgtagacatt atcaatagca ttgctaatca tgtcatttcg agcggacaac accgcttcat
     4021 gacgacccgc cattccataa aaaatgccca tatcatccgc ccatttttta taggccacaa
     4081 caacatctgc tggaatcgga gcttggaaaa taatagtttt agcatcgtct ttgacataag
     4141 ctccatttaa tttgacacaa tagtcagcat gtaaatcttg aacttcttgt ggaacaccgt
     4201 accgagcgcg acctgaagca ataccaacca agatgccttt tgccttcaaa gccttaaata
     4261 ctctttgaat cgactcaggc atataacccg tatctttgac cctcaaggta tcatcaatat
     4321 caaagaacac cattttgatt tttttagctt tgtattttag ttttgcgtcc atactttcct
     4381 ccaatttgct atactctata ttatagcatt aattatcgtc ttgggggact aaatggtgtc
     4441 gaaaagcata gacaaccgct tgggttcggt catcaacttc taacttggct agaatattgg
     4501 acacatgtgt tttgacggtt tttaaggaaa taaagagttc atcagcgatg gtctgattat
     4561 catacccttt agctaaaagg tgtaaaatat catactcacg cgctgttagt tcctcatgca
     4621 agtcagggtg ttgatcatgc gccttaattt ttttgtcaac ttctgtttca atggctaact
     4681 ctccctttga aaccttgcga atggcattta aaatttcagc cgcactcgat gtttttaaca
     4741 tataaccctt cgctcctgca tcaatgacag ggtatatctt ttcattatct agataggaag
     4801 ttaacacaag taccttagcc tctttccatt tttttaggac ttctaaagtt gcctcaacac
     4861 cgcctaactc tggcatcact agatccataa ccaaaacatc tggcttcaaa gccaatgcta
     4921 aatcaacccc ttcacgtcca ttagaggcct caccaacgac atcaatatca gcttgaaaat
     4981 tcaaaaaact cttgagtccc atgcggacca tttcatgatc atcgaccaat atcactttta
     5041 tcttactcat cgtcatctcc cttcactatc ggcagtctaa tatccatgga aactcctttg
     5101 cctttttgac taattaaatg taggtttcct gctaaatcat tgacacggtc ttcaatattc
     5161 ttcagaccat aactcaaatc ccttacctga tccatatcaa atcctacacc atcatcaatc
     5221 atcttcaatt gtaattctgt tgaggtttga ttgagataaa cttcaattcg actagcttta
     5281 gcatgtttta acgtgttgct aatgaattct tgggcaattc taaaaagatt atcttccatt
     5341 gttttaggaa gctgagcaat ggtttcctta taaatgactt caatatcact tttatctgtt
     5401 aattccttaa gaatcatatg aaggccctca gataaagtcc gattagctag ctcggtaggt
     5461 ctaagatgca aaaggagaat gcgtagatca ttttgagcat tttgcaacat tgcttcaacc
     5521 gttgttaact gtgtttgtaa ttgtgttttg tccagttgtt ccaaactcat cgaaattcct
     5581 gataaaatca atgacgaagc gaatagctct tgactgactg tgtcatgtaa atctcttgca
     5641 attcgtttgc gctcttgttt tacaacttct tggctatcaa gaatataagc actttctttc
     5701 ttttgcatgt tagcagtcag gtgagacatt tttttagaaa gtcgacttaa attagtattg
     5761 atttctgatg tctcatctag atagagtcgt cgattattga gaatatattt tagattttgg
     5821 ttgatgttac gcttactgtt atcatccata ataatccaca ataacaacaa taataaagtc
     5881 acagaaacaa tcaacaataa aatcgaaaac cctagacgtt cgacctgcca taaatgattg
     5941 cgaaggtagt taaaagtgat tcctaaatta tccatgacca caaaaacaat agataaaatg
     6001 gtaatggttg agtagagcca aacaagagca tagtaacgtt ttttcatcgc ctatccacct
     6061 caacatttcc ggcaatagtt gtaacgataa ttttgacttt tttaagggat tgattatccg
     6121 tttcttttaa cttaatagat tcgttgcgca aatcatattg ctgacatcta aaaaaatcaa
     6181 cgcttccgta tatggaacta acatctaaag taacagtgac atcaataggt accaatatag
     6241 tcgtatttcc aaaaatttta cgtatcacaa tgatattatc cattcctgtc acaataacat
     6301 tggttaagtc aaccgtgtca tttcctgaga ttcgaatgat gttaatgtca tcaaaacaat
     6361 aataatcact ttcataatta gcagtaccaa tccattgatg cttggtatta ttcacttcaa
     6421 tcttttcttc cttgaaacga atcaaggcaa agcgattctt ctttttgact tgtgaaaaat
     6481 ggttaatgaa aatgtaaact atccccaaaa gaacagccat gataatgtag ggattaagca
     6541 taaaaattaa aaaaagaaac aataaactga cagttagcaa aaaattattg cggctatctt
     6601 ggttataaaa gcgtaatgct aataagataa gaactagaat taggataaaa cttgataaat
     6661 cattatccaa gattgtcatg atacccatag ctagcagtat acactcgata agtaaaaaga
     6721 attgaaattt tttcattagt ttccccttat ttctttgtat tttatcagaa ttcctggaaa
     6781 attgcatctt tatatgacga gtagttaaaa agaatagtta gtggcatgct agtaaaacat
     6841 gagactaact attctttgtt aaggtgtttg agcagtagtt tctgatgggc ttaattcagt
     6901 gttgctacct ggtgcagtac tatcatttgt tgaagaactg tttgaacttg acgttgaact
     6961 cgatgagcta ctagaagagt gtgtttcttc tggataaagg taaagactga tctctccttt
     7021 atcagacaga ctcaaagacg ttccatagta aggagattga ccactgacaa tagctttaga
     7081 actaggagaa tgaattggca caaagcccgt tgctgagcta gagcttggca cataagcttt
     7141 tattctagat gcatctatac ctaaagctgt taaggtattg actgcatctg cataactata
     7201 ttctgttacc ataggcatag tgatcgtatc actaacagca acactgagcg taattttaga
     7261 ctttccgttt ggattaaatt tatcacccgc acttggcgat tgactgatga ctgtattttc
     7321 aggatattca ttagttacaa tgcgctcaat tttgattttt gattttggaa caccataagt
     7381 ttctatcaaa ctattcatag cttcttgata atctagtcct ttgtagtttt ccatgtcaaa
     7441 acctttgttt ccaattgaca cataaagcgt aatgcttgag ccttgcctct tagctgttcc
     7501 tgctttagga tctgttctaa ctacatttcc ctcagcaacc gtatcactct caatttgcct
     7561 gattttaccc acttttagcc caacatcata cagttcttgt ttggcaactt taagactagt
     7621 gcctgctaca ttaggaactt tcacagaagt tggtttagtt agtataagat aagtaaagag
     7681 tgctacacct acaataaaga aagaaaaaag aattttgaat aaagtaccta aaaaacgacc
     7741 actttttttc tttttggtgg ggggctgtaa agcatctgtt tgattagttt gattagtttg
     7801 atctaatcga ctttcctgtg ttaacactgt tggggtaggg ggagacaatt ttacagaagc
     7861 ggtgggacct gaggccactt tggggagggg tttggtactt tcaacatcct caaagataat
     7921 cttacgctcc cgactacgat tataactaag cgccgtcatt aagtcacgac tcatttcaaa
     7981 ggttgacccg taacgatcac ttaatttctt ggctgttgct cgaataacaa cattctccaa
     8041 agcttgtggc acattgtggt tctcctcgat aatagatgga agaggcattt gaaaatgttg
     8101 caaggcaatc gtaacagcac tatcgccatc ataagggata tggcctgtca acatctcaaa
     8161 gagcataatc cccatcgcat aaatatcact ttgaatcgtc gctttggagc cgcgagcctg
     8221 ttctggagac aagtaatgaa cactgcctaa catcgaatta gtttgtgtca agcttgtttc
     8281 tgcaaaggct actgcgatgc cgaaatcagt tactttgaca accccctcct tagttagtag
     8341 gatattttga ggttttaaat ctctgtgtac aattcctttt tggtgggcta aagtcatagc
     8401 agaaaggact tcttccataa ttctaaccac ttcattatta gataatggag catgattttg
     8461 aatgtatctc tttaggtcag caccatccac atattccatt actaaaaatt gctgtccgtc
     8521 ttcttcacct atatcccgga tggcaacaat attgggatgg ttcaattcag ccatggcccg
     8581 cgcttcccgt tggaaacgcg caactgctac ctgatctgtt tgataattgg tacgcaagac
     8641 cttgattgca acgtcttcat tatccaagat caaatcattt gctaaataaa catccgccat
     8701 accaccgcgg ccaatagatt tcagaatgcg ataacgacca gcaaataatt tgccaatctg
     8761 aatcattcga cgtcctcact ttcgttgtga accaaagcga ttgtaatatt atctaggcct
     8821 cctcttaggt tagctaagtc aatcatttct tggttttttt catcaagact aaccttactg
     8881 cccaagatag tcacaatttc atcatttgaa atcatattgg ttagaccatc actgttaatg
     8941 acaagataat cccctggctc caaaactctc actcctaaat caggctctac tggggaagct
     9001 tgaccaatag attgagtgat aatatttctt tgtggatggc tagcagcttc ttcttctgtg
     9061 atctgtcctg ccttaaccaa ctcattcact aaagaatgat cactggtcaa taaggtataa
     9121 tgcccatcat ggacaagacc aatccgtgaa tcaccaatat gagcataaat ggcgctagat
     9181 tcaactaaag ctactgcttc aacagtcgtt cccattcctt taaagtcttc tgattggcct
     9241 agatcataaa tccgttgatt ttctgactgg atagtttcaa ataaccaatc tctaatctga
     9301 cttaactctg tgaagtctgt ttttacccat tctcttccca ggtctgtgac tgtcatctca
     9361 ctggcaatat ttccagctct gtggccaccc ataccgtctg ctaaaatcac taaagtgatg
     9421 ccttttttat tatcaaactt attgataaaa tcttgattgt ttgagcgttt ttgcccaatg
     9481 tctgttttta atgaaatctt catacgtttt ttctgactca gtcagtttcc tcctaaaata
     9541 ctacaagact cgtctgactt gtccaataaa gaagccatca gtctggtatt gttctggtgt
     9601 gataataaga taaccatcct tgacagtatc tgcttgtgta tggttcagtt ttacttgttc
     9661 aaaattagga tgactctgta aaaatgcttc gatgacttga cgattctcct catcaaaaat
     9721 agtgcaagta ctgtatgtta ttataccacc tttacgcaag gtttgacaaa cactagacaa
     9781 tatctctagc tggatagcct gtagagcatt aaaatcttga ctttctttat tatatttgat
     9841 atcgggtttt cgacgaatca aaccaattcc tgaacaagga gcatccacca aaatcttatc
     9901 aaagctatcc ttttcaaaat gacgatgaac ctctctggca tctagttttc ttgtctcaat
     9961 gttatcagca actcctaagc ggttagcatt ttccttcacc aactctagtt tatgatcata
    10021 gagatctaag gcaataactt tacctgtttt taagtaagat gctatatgag aggtcttacc
    10081 ccctggagcg ctacacgcat caagaattat gtcgtcaccg tcaatgttta aagtaggagc
    10141 tacaagctga ctgctttcat cttgaatagt gatgtcccca tttgtgaaat aatcactggc
    10201 tgcaaaatga cctgacgctt tggttaaacc agttgctgat aaaagggaac gttctgcatc
    10261 taaagcctca gcaacttctt ctaacttcaa agggtccgtc acgcgaatac tagccttact
    10321 acgcacaaat aaactctcca taatagccac tgctctgtgg gagccaaatt ggtcttctaa
    10381 ctttttaacc aaccaaacag gcagtgaata cttgaccgaa taatacttat ttcgacgctt
    10441 aattgtttcc atatctggga gaggatggct ggtgaattga cgtaaaatag cattgacaaa
    10501 cttctctgca ccttttttat tgccacgatt tttggcaata ccaaccgcat cgttaacaat
    10561 ggcatgcgct ggtaacttat ctaaataaat cagttgataa agactgagca taaggagata
    10621 ataaacccat ttgtccaatt tatctcggtc tttgacataa tgggctaaat accattccaa
    10681 gctaatttta cgtgaaacgg taccatatac aatctcagtt aatagagctc tgtccttagc
    10741 agataaagct ttattgctta gctgctgatt aagcgctatg tttgtgtaag ccccctgatc
    10801 aaaaatagct tcaatgacaa ggagggcttt gcctcgcgta ctttttttcc aattatctgc
    10861 caatgatgtc ccctacttca agttttctac caatgccgtt taaaaagtct attattgaca
    10921 ttttaggttt accagccggt tgcacaacga tcaaggacaa agctccttgt ccagtagcta
    10981 ttaccaaaga ttttttggtt ttgacaataa cttgtccagg taatccttct ccttcagcta
    11041 gttgagcttc gtaaattttt aaacgttgcc cctctaaaaa cgtatgcgct accggccaag
    11101 ggttcatacc tcgaatatga ttgaacactt cttgattaga cattgtccaa tctaattttt
    11161 cttgttctgg agagatatta ggtgaaaaag tagcttggct gtgatcttga ggaataggtt
    11221 ttaattctcc agaaagataa gctggcaaac tatccaaaag taagtctcga ccaatgatgg
    11281 ctaatttctc aaaaagagta cctacattat cggtttcaag aattggagtg cttgctttag
    11341 cgaccatgtc acctgcatcc atttctttaa tcatttccat aatagtaacg ccagcctctt
    11401 tatctccatt cataatagca taatggatag gtgctccacc tcgatattta ggtaacaatg
    11461 atgcatgtac attaatagca aatgaaactg aatcaagtaa tagtgttggt aaaaattggc
    11521 caaatgctgc tgtaataata ccatctgcac caagtcccat aatctcaatg agttcttgag
    11581 agcctgataa tttttccggc tgatagattg atattccatg ctcaagagct aattgcttta
    11641 caggtgttac cttaatatct tttttgcgtc caacagctcg atcaggctga gtaaccactc
    11701 ctaaaatctc ataggcagga ttatctagca agcccttcaa tacagttgct gaaaattggg
    11761 gagttcccat aaataataat tttatcatga ctttcctctt tgtattttta ttatatcata
    11821 actgatcatc ctagatttag tgatttacct tataaaaatt gttgcggttc acaatcaata
    11881 attagtttta aatgacgatt atctgcttct tgactccaat caagaatacg attgagcgtc
    11941 tcttctaggt tatcttcaaa acggtatttt aacaaaattt gatagtggta taaattgtgt
    12001 gttctagcaa ttggcttagg agtcggtcct aatattttaa tattatccga taagagactc
    12061 tttagcagtt ctgtaacttg ataagctttt tttacaaccg atgcttctaa acgatgcgaa
    12121 agcgtaatac ccactgtaaa gtagtaaggg ggataagcca tctgacggcg aatcgccatt
    12181 tcataacggt aaaaggcttc aaaatcttgt ttcttagcta attgaatagc atagtgatcg
    12241 ggattataag tttgaatcaa gacttctcct ggcttatggg cacggcctgc ccgaccagca
    12301 acctgtgtta acaattgaaa cgttttttct gacgctcgaa aatctggcaa atttaaggag
    12361 gtatctgcat ttagtacccc aactaaagtc acatttggaa aatccagtcc tttggcaatc
    12421 atttgcgtcc ctaacaaaat atctgcttcc tggcgaccaa aactatctag tatggttttg
    12481 tgacttcttt tttttcgtgt ggtgtcaaca tccattctca agatcctagc ttctgggata
    12541 accccttgca attcatcaaa agctttttga gttccagtgc cataatagcg gatactgttg
    12601 ctatgacact caggacaagt aattgggata ggtttttgaa acccacagta atggcaattc
    12661 atagttttag tatccatgtg aagggttaag gagatatcac agttgggaca tttgtccaca
    12721 taaccacagt cccgacacat cacaaaacta gaataaccac gtctatttaa cattaagaca
    12781 acttgttctt ttttaaccaa acgttcttta atcttatcaa tcaaatatgg ggtaaaattg
    12841 ctaactgctt gctgtccaat ataatcacga aaatcaacaa tcgttacttc tggaatctta
    12901 gcaagaggat ttgctctttg cgttaattga ataaaatgat agaccccctt actagccctt
    12961 gctcggcttt caatacttgg cgtagcagag cccataacca caactgcttg atggtgttta
    13021 gctctgagca gggcaacctc tctggcatgg tatctagggt tgctttcttg tttataggtt
    13081 gattcatgct cctcatcaat aataattgca ccaatccgct ctagtgggga gaaaatagca
    13141 gagcgggcac caaccacaac cttagcctgt cctgttttta tcttgcgcca ctcatcaaac
    13201 ttttcaccat ctgataagcc tgaatgcata atagccactt gctttccgaa acgggaaata
    13261 aaacgagagg tcatctgagg agtcaacgaa atttctggta ctaaaacaat ggctgtctta
    13321 tcctgtttta aaactgcttc gatgatatga agataaactt ctgtcttacc cgaacctgta
    13381 atcccttcaa tcaaaaaagg tttactcggt ttcccaattt gctcaacaat ttcagtaaca
    13441 gctgacgctt gctgttcatt taaggttaaa aaagaagatg gtttgatctg gtcaaaatag
    13501 gactcactgc gatcaatttg acgttcgtca atacgaatta agtgatttgt cacaaagtaa
    13561 gccaccacat ctcgagaaaa ggcttgataa agcgttgcaa gtttagcttc cttcgtatgg
    13621 gttagcagat agtcttttaa taattgacgc tttttggcac gactagagat gggatgtacc
    13681 gctaaggcgt ctaagtcgac gtgataatat ttttctgtct ttaggttttt cttgtctttg
    13741 gctaaataac taacagtaat atgcccagct tgtatggcct taagagctat tttttccttc
    13801 tcgcggtcta aggtagaata taagacagat ggttttcctt caaaaagaaa gtctctatca
    13861 ggctttttta gacctgactc tggccttagc actttatcat agttagagtt aagaagatta
    13921 ggaatcattg cttttaagag cgtgatttta taagaaaaaa ctgtttttcg aagctgatca
    13981 gcaagggtca attgttcttg gtttaggact ggctcaggat ctaaaacggt ctgaatcagt
    14041 ttaagagagc ttgaatcttc ctggccaaaa ccaataacaa agccttgcaa caaacgattc
    14101 ccttttccaa aaggaacatg cacacgagaa ccaagctgca cgagagaaac taactctttt
    14161 ggaataccat aagaaaatgg cttgtccgtt tgcatcaatg gaatatctac aatcacatga
    14221 gctacttttt ccatttgctt ctccttttct gtcatggaca tcgtactaaa tatgaaaaaa
    14281 tctaagattt ctgaaacctt agattttttc tccttcttct tctttttctt tggcaatttg
    14341 ttctttgatt ttacgttcct cttcctcttt ggccaagcgt tctgcctcaa tcttagcacg
    14401 gacagcttca cgtttagctg aaggatctgg gtgaatcaca acgtttcctg attcaatttc
    14461 ttcaagtgcc tgaagtgttg acttcactga tttaaattct tgagttggag tggcaccagc
    14521 ttctagttca tgggcacgtt tggcttgtaa aatcacaagt gaatacttag atggtacttt
    14581 atctaataag gtatcaatgg aaggttttaa catcataatg cttactcttt tctatttagc
    14641 tttaaaggga ttttttgtta ttttaatcat tttatcataa cgaccaatca cgcgctccac
    14701 acgaaagtgt tctgtctcaa tgatacgctt aacccgctca gctgccaagg caacttcatc
    14761 attaacaact gcataatcgt attcgcgcat aagggcaatt tcttcttttg ctctttcaat
    14821 acgttgagct atgacttctt gactatctgt accacgacca accaggcggt cttctaattc
    14881 atctaaatct ggtggtgtta aaaaaacaaa aacaccatct ggtacttttg acttaacctg
    14941 aagagctcct tgaacttcaa tttctaaaaa gacatcaatt cccttatcaa gagtctcatt
    15001 aacataagtt aaaggggtgc catagtaatt accaacatat tcagcatact ctagcatttg
    15061 accagtttta atgagttctt caaattcttc acgtgtgcgg aagaaataat caaccccatc
    15121 aacctcgccc ggtctttgcg gacgagtcgt cattgaaacc gaatattcaa atttatgatc
    15181 tggcgttgaa aaaatttctt gtcttaccgt tccttttccg acacctgaag ggccagaaaa
    15241 gacgattaac aaaccgcgtt cagacattgt attctcctta ttagttgctt tttaatagtt
    15301 tatcaaaaag gctagtcttt ttcaagaaca ttttcaaagg taagtcataa agaaaaagag
    15361 gataattcct ctttttctac ttggcataat caaccgctct catctcacga ataacagtta
    15421 ctttaatatt tcctgggtaa tctagattgt tttcaatttt ttctcttact ttatgcgaca
    15481 aaatgacaac ctgatcatct gaaatttttt caggttgaac cataatacga atctcacgtc
    15541 cagcttgtag agcaaaacta ttttgtaccc catcaaaact tgtcgcgatt tcttctaaat
    15601 cacgaagacg cttgatgtaa ttctccattg actcattacg agcgcctggg cgagccgaac
    15661 tgagagcgtc tgctgcagct actagcacag cgatcacaga atctggctcc acatctccgt
    15721 ggtggctagc aatagtgttg acaacaactg gatgttcttt gtatttacgt gcaaattcca
    15781 ttccaatctc aacgtgacta ccttcaacct cacggtcaat agctttaccc atatcatgca
    15841 agaaaccagc acggcgggca agagcaacat tttcacctaa ctcaccagct aaaataccag
    15901 ctaacttacc aacctcaaca gagtgacgta ggacattttg accaaacgag gtacggaatt
    15961 gcaggcgtcc catgatttta atcaaatcag gatgaaggtt tggtgcacca atctcatagg
    16021 ctgcagcttc accgtactca cgaatacgat tatccatttc aagacgattt ttctcaacca
    16081 attcctcgat acgagctgga tggatgcgac catcagcaat cagagattcc aaggtcatac
    16141 gagcaatttc acgtcgaata ggatcaaatc ctgataagat aacaacttca ggagtatcgt
    16201 caataataac gtcaatgcca gtcaagctct ctaaagtacg aatattacgg ccttcacgtc
    16261 caataattcg gcccttcatg ttgtcgtctg ggagatggac actggtaata gtttgttcag
    16321 tcacatactc accagcaaga cgttgcatgg cttgcgctaa caagtccttg gctgttttaa
    16381 ctgttcggtc cttgatgtca cgttcggcat ctcgaatgcg ggtcgcaatt tcatgggtca
    16441 gtttgttttc cgtctccatt aaaatcactt cacgcgcttc tgcaatcgtc atcgcagcaa
    16501 ctttttccag ttctgctttt ttctcctctt caagtttttc cacttgaagt tgccgctcat
    16561 caatgtgttt agatttatcg gtcagacttt gttctttact atctagtacc ttttctttac
    16621 ttgataggtt ttcatcttta cggtcaagag ttaaggagcg ctccgctaag cgtgtctcga
    16681 gttgtttaag ctcttgtctt tcagacttaa attcttgttc aatctcttca cgatattttc
    16741 ttgcctcttc ttttgcttct aaaagtaatt ctttacgatt tgctttactt tcacgtttag
    16801 ctgttttttt gatgtgttca gcatctactt ctgctttgcc acgaatatca acagcttctt
    16861 gttcagcgtt taaaagagtc aactctgcag cttccttcgc agacttgagt ctaatcgaaa
    16921 taagtgcata acctaatatt aaaccaatga gggcagaaac aattaataaa ataatattaa
    16981 ccatgtttgt acctcaatat attctagatt tcattaatag aaagccacct cttagtttat
    17041 cataaattga gcgtttacac aattccaatt catttttaaa aaaattaaca tctgggccaa
    17101 gtggttgaga accctactta aaaaaagact gtagcaagtc gtccatgatg taggcttcta
    17161 tttcagaatt acttttttcc ggaggcgtgt taagacaaca cgccaagaaa tgggacgttc
    17221 cattggaata cacttaatgt cctttaattg gtataattct gtaataggtt tgggacaaat
    17281 agttaagacg ttgtgattaa tcttggtaga attaagcata aaatcccagg aagaggacgt
    17341 caaaataata ttaggtctga cttggtgacg ctcgcaagct tcaagcacta aatggtgaac
    17401 catgaaacta ggatcaaata gggcaagttg ttcatctgtt aaatcttccc actgaataac
    17461 ttttttggaa gctaaacgat gacgtggaga caggcataca gataattctg atctctggat
    17521 ttcataagtc tcaaccaaat tatcagcgat gcctgttggg gataacaaga ctgcgacgtc
    17581 aacatttccc acgagtagtt cattttttag ttggtaagca ccaatctcct taacattgaa
    17641 ttgaattccc ggattttcta aaatcagttt tggcattact tctgagaaaa caactgataa
    17701 aataagagga ggaataccaa tattgatact tccctttaac cctttactgt gatcatgcaa
    17761 tttcaaaaac atgtcatcat agagactgag aaccttttga gcgtccttat aataattatc
    17821 accaagatag gttaacccaa taatacgacc tctttttcgt ttgaagagct taacattttc
    17881 ccttttttca aaatcattga tcatcatgct aagtgtcggc tgcgacacat acaacagttc
    17941 cgccgcctgg ctcaagttaa aatgattttc aacgattgcg ataaaataac gaatttgttt
    18001 aatatccaaa tggttatccc cttgtctatt agtctttttt ccgatagtat taattccatt
    18061 atgacataag tgatttttaa ttgctattgc caaatctatc aaaaaaattt atatgcttat
    18121 aaaaattcta tatttttatt ttgagcggtt tcttgttatc ttagagatac agaaaacgct
    18181 ttctaaaaat gaaaggatgt ttattttatg aaaaacatag ttatcgttga agctttacga
    18241 actcctatcg gagcttttgg aggctccttt aaaagtgtct ctgctgttga acttggaaca
    18301 actgtactga aaaaaatcct tgataaaacg caagtaaagc ctgaaatggt tgatgaagtc
    18361 atcctaggaa acgtccttca tgcaggatta gggcaaaacg ttgccagaca gattgctatt
    18421 cactctggca tccctagtga taaaacagcc ttcacgcttg atatggtctg tggttcagga
    18481 cttaaagcaa tccaattagc tacgcaaagc atcatgcttg gtgacgctga tatcgttatt
    18541 gctggtggtg tcgaaaacat gtcacaggca gcctatgtgt caactcagca ccgttttgga
    18601 cagcgacttg gtaatagtca attgattgat actcttgttc atgatggatt gacagatgct
    18661 ttcaacaatt atcatatggg tatcactgct gaaaacgttg ctcagaaata tggcatctca
    18721 agagaagagc aagatcaatt tgctttagaa agccaagaaa aagctgctaa ggcattagaa
    18781 aatcatcgtt ttgctgacga aattgtccct gtctctgtgc ctcaacgacg caaagaccct
    18841 ttaattgtta caacagatga atacccaaaa gttgacacaa gccttgaaaa attacagcaa
    18901 ttacgtcctg ccttcctccc taaagaagga accgttactg ctgggaatgc ctcaggaata
    18961 aacgatggtg cagccttatt gatgttaatg actgaagaaa aagctcttga attagggtta
    19021 acacctttag tcactattga aagctatgct agtgcaggtg ttgcacctga actgatggga
    19081 gctggaccaa ttcctgccac tcaaaaagtc cttaagaaag ctggattaac aatttctgat
    19141 ttggacttag tggagtccaa tgaagcattt gcagcacagt ccttggcggt tttaaaagat
    19201 ttaaagttaa acccagaaat cgtgaatgtt aatggaggag ccatcgcttt aggtcatcct
    19261 attggtgcca gtggcgctcg cattctagtc acattaatcc acgaaatgaa aaaacgccaa
    19321 gtaaccagag gactagcaac actttgcatt ggtggaggac aaggaactgc tgttatcgtg
    19381 aaaaacaata cttagtctcg tgaaagttgg tagaaaaaat gtgtaaagaa atcacaataa
    19441 aagaagcggt agctcacgtt aaagatggtg ataccattat ggttggtggc ttcatgacaa
    19501 atggcacacc agaaaaatta attgatgcac ttgtggaaaa aggtgtcaaa gacctcactt
    19561 taatctgtaa cgatgccggt tttcctgaca aaggcgttgg taagatggtt gccaataaac
    19621 agttttcaac tattattgca tcacatatcg gtctcaaccg tgaagcgggc cgacaaatga
    19681 ctgagggcga gactgtaatt gatcttgtac ctcagggaac attagctgag cgcatccgca
    19741 gtggcggttt tgggctaggc ggtttcttaa cacctactgg aataggaacc gaagttgcca
    19801 aaggaaaaga agtcattact attgacggca aagactacct tcttgaaaaa cctttgaaag
    19861 ctgatatcgc acttattttt gctaacaagg cagataaaaa tggcaatttg caatacgcag
    19921 gttctgaaaa taactttaat catgtgatgg ctgctaatgc gaaaaccacc attgttgaag
    19981 caagagaagt tgttgacgtg gggcaaatgg atcctaattt tgtccatact cctggcattt
    20041 ttgttaacta cttagtgaaa ggagcctaac atgggaacat cagctactgt tctttcaaaa
    20101 gaagagattc aaacacgtat tgcaaagcgt gtagcacaag aattagaaca caatacactg
    20161 gtcaacttag gcataggttt gccaacaaaa gtagccaact atattcctga aggtgtaacc
    20221 attaccctgc agtccgaaaa tggttttgtc ggtctcactg gattaacaga tgatcactac
    20281 gatcctagta ttgttaatgc tggtgggcaa cctgttagta ttgctcctgg aggggctttc
    20341 ttcgatagct caacttcctt tggtattatt cgaggcggcc atgtggccgc aaccgtctta
    20401 ggtgccttac aagttgataa agaagctagc attgctaatt acctgattcc tggaaaaatg
    20461 gttcctggga tgggaggggc catggactta ttggtaggtg ctaaaaaagt cattgttgca
    20521 atggagcata ccaataaagg caaagcaaaa attttagaca aatgcaccct tcctctgact
    20581 gctcaaaatg ttgttaacct aatcattact gaaatgggag tctttgaata tcaagatgaa
    20641 ggtctatgcg cccttgaaat taaccaagat tacacctttg aagacgtgca aaacgttacc
    20701 gaagttaccc taattgataa aacaaactaa agactaacca aaagaaagac gaggatagta
    20761 tcatgacaca tactaaagaa gttgcattta tcactggtgc tgcaagcgga attggaaaac
    20821 aaatcgggga aaccttatta aaagaaggta aaacggttgt tttttctgac attaatcaag
    20881 aaaaactgga tcaggttgtt gctgactata ctaaagaagg ctatgacgct tttagtgttg
    20941 tgtgcgatgt caccaaagaa gaagccatca atgctgctat tgatacggtt gttgaaaaat
    21001 atggtcgtat tgatattttg gttaacaacg caggccttca acatgttgcc atgattgaag
    21061 attttccaac tgaaaaattt gaattcatga ttaaaatcat gttgacagca ccatttattg
    21121 ccattaaacg tgcttttcct acaatgaaag ctcaaaaaca cggtcgtatt attaatatgg
    21181 cttctatcaa tggtgtcatt ggttttgctg gcaaatccgc ctacaattca gctaagcacg
    21241 gcttgatcgg tctgaccaaa gtaactgcct tagaagctgc tgattcaggc attacggtca
    21301 atgccatttg tcctggatat gttgacacac cactggttcg tggccagttt gaagaccttt
    21361 ccaaaacaag aggtattccc cttgaaaatg ttcttgaaga agtgctatac ccacttgttc
    21421 ctcaaaaacg cctcattgac gttcaagaaa ttgcagacta tgtgtctttc cttgccagtg
    21481 ataaggcaaa aggtgttaca ggtcaagcct gtatcttaga cggtggctac actgctcaat
    21541 aaatttggag agataaagag gctgtatctt gtgatctgtc tctttatttt ctaataagga
    21601 ggtcataaaa ctatggaaat tattggttct ctaggggtct tggtaggtgt tattgttatt
    21661 atttacctgt ctgtcaaaga agttaacatt atcatcgctg cgcctcttgc taccagcttg
    21721 gtcatttggt ttaatcaaat ggatccaacc acaaccttac ttggaaaaga acccaaccaa
    21781 tttatggggg cactctccac ttatattctc aattattttg ctatcttttt attaggttct
    21841 atcttagcca aattaatgga aacaagcggt gcaaccactt ctattgcaga ttatatttta
    21901 aaaaaagttg gtcatgatag tccttataaa gtactcgttg ctatttttct gatcagtgct
    21961 atattaactt acgggggaat cagcctcttt gttgtcatgt ttgctgtctt gccgcttgca
    22021 cgaagtctat tcaaaaaaat ggacttggct tggaacttaa ttcaagttcc tctttggctc
    22081 ggtattgcga cttttaccat gacgatttta cccggaacac ctgccattca aaatgttatt
    22141 cctattcaat acttggacac ctcactaact gctgccgcca ttccgagtat cgttggctca
    22201 attggctgcg tgacttttgg gctcttttat atgaaatatt gtctagcaaa aagtatggca
    22261 aggggtgaaa cttataccac ttatgctttt gacaatgaga tacaagtgaa aacaaaaaat
    22321 ctcccacatt tccttgccag tatcttacct ttattgttgc tcattattat cgccctaacc
    22381 ggtagccttt tcggaaacga tttttttaag aagaacatta ttttcatagc acttttagct
    22441 gccattctca ccgcaagctg gctctttaga cagtttattc ctaataagat tgctgtcttt
    22501 aatttaggag ctagcagctc tattgcacct atttttgcga cagcatctgc agttgccttc
    22561 ggagccgttg tgatgattgc cccaggtttc acattcttct cagatctcat tttgaatatt
    22621 cccggtaatc ctcttattag tttagccgtg ttgacttcct ctatgtcagc tattaccggt
    22681 tcttcttcag gtgctctagg aattgtcatg cctaactttg cccagtatta tttagatcaa
    22741 ggccttaatc ccgaaatgat tcaccgtgtt gccactattg cttcgaatat ctttaccatt
    22801 gtgccccaaa gtggtgtctt tctcaccttc ttagcattga caggacttaa ccacaaaaat
    22861 gcttttaaag aaacctttat tactgtttct gtaagtactt ttatcgcaca ggtcattatg
    22921 atagcctttg atctgttttc ttagcctttt ctcctccaca agtagccact ttctcactat
    22981 ttgtgttatg ataaagtgta aaacaaagga gattgaaatg acaaaagaag ttatcgtcga
    23041 aagttttgag ctagatcata ctattgtaaa ggccccttat gttcgtctta tttctgaaga
    23101 atttggaccc aagggcgatc gtattacaaa ttttgatgtt cgcctagtgc agcctaacca
    23161 aaattctatt gaaacagccg gtttgcatac cattgaacac ttacttgcca agctcatccg
    23221 ccaacgcatt gatgggatga ttgattgctc tccttttggc tgtcgaacag gttttcacct
    23281 tatcatgtgg ggaaaacaca gttctactga tattgccaag gtgattaaat ctagcctaga
    23341 agaaattgca actgggatta cttgggaaga tgttcctgga acaactcttg aatcctgtgg
    23401 aaactataag gatcatagcc tttttgccgc caaagaatgg gctcaattga ttattgatca
    23461 agggatttca gacgatcctt ttagtcgcca tgtcatctga tactagtgtg ttgtcaaaca
    23521 taacaatcct actgacctat ttgacttgtt acaaaaaaca agtctatctg cagattttaa
    23581 gacaacatac tttattaatc aaaaaactga gacaagttgc cttatctcag tttttttgat
    23641 tttctcagta atctaaagca tcagcataac ctttgccatt tcctacaaaa taacccgtct
    23701 tacaattaat agagaacaga taagtgccat caggcttaaa catattatag taaccattgc
    23761 cattaataat attaaccggc tctaaaatat attggttgcc tgaaatataa cctctagctt
    23821 gtgaggttgc tacaattttt tcaagaactc ctggattaaa tgcccaagat gggttagctc
    23881 tgtcagcaat aacatcttga ttgtaaggta cacgtgataa atgccgttgt aagcttgcag
    23941 gatcataact tgtcaagcca tagccagatg gtgctactga tgtactttgt ccttgagctg
    24001 cttgatcctg ggcttcttgc tcattagctg ctttagcggc ctcagccttg ctggctagtt
    24061 gctgacgacc ttctgtgatg cttgcctgca agacagcatc aagatttgca tttcctgttg
    24121 tcaaggttgc acttgataaa tcatcaaaat tagcatcagc cttgacttca gccgaaacct
    24181 tttcaccatc tacaacagca tcggaaacaa atttaccgtt aaccgctgta atagcagcaa
    24241 tagctttctt aagggaatcg acttttgctt tcgccttatc atagtaagca gagccttcca
    24301 aagctttcaa ggcagcttct aaatctggca aagtagcaaa ggcactattt tttaatttgc
    24361 tctttgtggc atctgtataa aaagtaccat attgtttttc gaaagcttta gcagcagcct
    24421 ttaagcgcat tgctttttta gcactgtcgg tctgcaaaga ggtctttgtc tgtttacttg
    24481 ctgtttgagt tgttttacca ctgtcttgtc tcaagaagtg gttccaacca aatacaactg
    24541 caagaatgcc caataatagc agaaataaag ctattaacca accttttttc gtgttttgtt
    24601 tggctggatg gtggctatct tcagaaagaa actgatctct ttttggttct tccttggtca
    24661 tctgtggttc tggaatgacc ctctctgatg gatctagatc taacacaggg actgtcgctt
    24721 ccaccggaat cccagttacc accgcagtag tctccattgg agctaagtct tcagctactt
    24781 cttcaaccaa agtgctatct tgctcagcag actccgcaga cacaggttcg tcatcaacaa
    24841 gaccggcttt actcaatgct tctctttgtt ttttgataaa gttatctaaa ctagctgtat
    24901 caagctctgt atacttagca tcaaactttt gagaagaaac ttcgtcacgg tgttgcttaa
    24961 tgtacttatc taaaatacta tcatccttag taacacctgc ttttatctct gactgtttgc
    25021 gtacagcttc accaattgtc attgacttgg cttcattaag ccccaatgtt tgcgattctt
    25081 ttgttacttc gacttctttg ctttcttctg acacgcttac tacctctcta tatcagatgt
    25141 cgctttaccc tttccccata aaattggtac aaatcaactt ttagggtgcc gttataaagt
    25201 ttacgttttt tatcagcttt ttgcccgtat tttagttcaa aaagttcatc acttgtaagg
    25261 ataaatttgc tccatgtttt caatggtgca aaggtttgtc ccatttcatt atacaagatg
    25321 tcaaccgctt tgtcatcaag caaccgttct ccataaggag gatttgatat cactacacca
    25381 ttaaccttgt ctgttcgaaa gtcttgcaga cgcatttgct taaaggtaat cacatcagat
    25441 aaaccagctt cttcagcatt acttttagca atctcaatca tgcggccatc gatatcaaag
    25501 ccagaaatat ctaattcgat ttcataatta gcttcttgtt cggcatcatc acgaacttgt
    25561 tgcaccatgt ctttatctac ccagctccat tcttcaaaag caaacgaacg gttaaatcct
    25621 ggagcaatat tcatcccaat cagggctgcc tcgatgcaaa acgttcccga tccacaggtg
    25681 ggatcaacca gaggtttatc tggaaaccag ttagataagg ccaagatagc agctgccata
    25741 ttttctttaa taggagcccc acccttttga acgcggtacc ctcgtttaaa taggctagat
    25801 cctgtcgtgt caatcataat agtggcttgg tcttttaaaa tagatacctc aatattaaac
    25861 gttgacccaa cttcttgaag aggaactcct tctggcctgt ggaaatgttt ttgcagtttc
    25921 ttaacaacag cttttttggt aatcgcctga acacttggct cattgtgtag ctttgacttg
    25981 acacacttgg cttttgagat tggaaactta gctcctagcg gtaaataatt tccccaatcc
    26041 aaggcaaaga caccttggaa taattcttca aaggttctag caggaaattg tcctacgata
    26101 attttgatac gatctgctgc acgtaaccaa agatttgttt taacaatcgc ttctacatca
    26161 ccttcaaaat aaactttccc attttcaacc tgacaatcaa aacctagtgc tctgacttct
    26221 ttaccaacga cagcttctaa acctgcggct gcagttgcga ctaatctaaa tgtttctttc
    26281 atatatctct ttcttttaaa tcaaataaaa gctagcaagt gctagcttaa cctattatgc
    26341 aattttctat aagccatgtt ttgttccgga aataactagg aattatttcc ttcgataatc
    26401 atctgtctac cgtctgttga cagtcaggat agcttgttcg tttccaacta tcccatgccc
    26461 ctaccaaagt ttgggttgct agcttgaggg gtttaccgcg ttccattttt tacgtttcca
    26521 taaaaactac gtcactgtgg cactttcaga agtactttgg catatcaaac gacttagcca
    26581 tttccttcgc cgtaatgtgt atgcacatcc ctaggcttat gtgttcgcct agcacaatca
    26641 ctactggcat cacagccagt gctagcatgg actttcctca tagtattaaa atactacgcg
    26701 attatccaaa aattgcacag ttttcattac tcaataattt gtttaccaaa aacctctttt
    26761 tccaatttac taatacgttt caagatgtca aaattagtag ctgattgagc aacacgagtc
    26821 ggttgcggta ctggttgttg aacagtcgct gaaactgtat ttctagcttg aaacttcgcc
    26881 ttttttaagg cttcgttctc agcttttaaa gcttcaattt gagcattgaa attttcataa
    26941 tctttaatta cattatcaag aaattcatca acttctttct tatcaaaccc tcgcatacta
    27001 gtcttaaatt cttgctcaaa aatatcttta ggactataaa taatacttgt cattctttac
    27061 tctccgaacg gtcaatcttt ttaccaaaat tatatttcag tattattaat gatacagaaa
    27121 aatagttcaa aaagcaagta tttaaatacc aataccccta aaaatacaat gctagctttg
    27181 tgacatatca tttagccgat caaaggttag caatagcaac tgataatacg gcatatcttt
    27241 tgctttcttg agaaaatatt ttaagttggt ctcgttttct gtgtcataaa aaacataagc
    27301 cccttctgtc ttttctaata aaaactgata atattgacta aattgcggcg gttgttcgta
    27361 atttggaaag taatatttta caaagtcaac agccctaaac tgacttaaaa cttcttgatt
    27421 tttttcattc cacttatctc catgcgtttc aaacaagaat atagtagcta tctgcaaggg
    27481 atactcctct tttagctcat tagctacttc caaagcccat tgttcaaaac ccaagttccc
    27541 tgtaaagata aaccaatcca caccattttc caaataacct attaaatctt tacgaatagc
    27601 ctgtttaata attgaaactc gtgggtcttt atggtcaaaa atccctattt caaagcttcg
    27661 gtaacctgta attagaatcg cagtcattag gtgttatcct ttcaaaaaat atgttataat
    27721 aaaagtgctt aaatttttag cattaactag ataatattag gagaacaatg gttaattatc
    27781 ctcataatct tattcgacaa aaagtaagtt ccgttcaaaa gcaaacaaag caaaataagg
    27841 tggacttcgc caatagaggt atgtcctttg aagctgctat caacgcgaca aatgattatt
    27901 atttatctcg tcaaatagct gtcattcaca aaaaacctac tcctgtccaa attgtcaaag
    27961 tggattaccc taaacgcagt cgggcaaaaa tcgttgaagc gtactttaga caagcttcaa
    28021 cgactgacta ttgcggcgtt tataaaggac attatgttga ttttgaagca aaagaaacca
    28081 ggcaaaaaac agctatgccc atgaaaaatt tccatttaca tcagattgaa catatggctt
    28141 gcgttttaca tcaaaaagga atctgctttg tccttcttca cttttccaca ctgaaggaga
    28201 cttactacct acctgctcaa gccttgattt cattttatca gatagataat ggcagtaaat
    28261 cgatgcccat tgattatatc agaaaaaatg gctttaaggt agcatttgga gcctttccac
    28321 aagtccctta tttaaacata attgaacaaa attttttagg cggtgattac aattaaaaat
    28381 ccaaaaatcc ttaagtggct aaagtatgta ttaagtgcaa ttcttagcct tattatcctt
    28441 gttattatta ttggtggtct tttgtttacc ttctacatta gcagtgctcc gaaactgtca
    28501 gaagcccagt taaaatcaac aaactctagc ttggtttatg atggtaataa caatctgatt
    28561 gctgatttgg gttctgaaaa gcgtgaaaat gtaacagctg atagtatccc tattaatcta
    28621 gttaatgcta ttacctcaat tgaagataaa cgtttcttta accatcgtgg agtagatctt
    28681 tatcgtattt ttggtgctgc ctttcataat ctaacgagtc agaccactca aggggggtca
    28741 acgcttgatc agcaactcat taaactagcc tatttttcta ctaatgaatc tgatcaaacc
    28801 ttaaaacgta aggctcaaga agtttggctt gctcttcaaa tggagcgaaa atatactaaa
    28861 caagaaatcc tgacttttta catcaacaaa gtatatatgg gtaatggcaa ctatggtatg
    28921 ctgacagccg ctaagtctta ttatggcaag gatcttaagg atttatctta tgcccaacta
    28981 gccctattgg ctggaatccc tcaagctcct agtcaatatg atccttacct tcatcctgaa
    29041 gctgctcaaa atcgccgtaa cgtcgtgttg caacagatgt acatggaaaa acatctgacg
    29101 aaagcagaat atgaaactgc catcgcaact cccgtcgctg aaggtctacg atcactccaa
    29161 cagcgctcaa cttatccaaa atatatggat aattatctaa aacaagttat tgaagaagtc
    29221 aaaaaagaaa cgaataaaga tatttttacc gctggtttaa aagtttatac caatattatc
    29281 cccgatgcgc agcagactct ttataatatt tatcattctg gtgattatgt ttactatcca
    29341 gaccaagatt tccaagttgc ttcaacgatt gttgatgtga caaatggtca tgttattgct
    29401 cagcttggcg gacgtaatca agatgaaaat gtttcatttg ggactaacca agctgtttta
    29461 actgatcgtg actggggttc taccatgaag ccaatcacag cctatgctcc tgctattgaa
    29521 tctggtgttt atacttctac tgctcagtcg actaatgact cagtctatta ttggcctgga
    29581 accactaccc aattgtttaa ctgggacctt agatataacg gatggatgac aatccaagct
    29641 gctattatgc tatcgcgaaa tgtcccagca gtccgagcac tggaagccgc aggacttgac
    29701 tatgctcgat ctttcttaag cagtttaggt attaactatc ccgaaatgca ctactcaaac
    29761 gctatctcaa gtaataacag tagctcagat aaaaaatatg gtgcaagtag tgaaaaaatg
    29821 gccgctgcat acgctgcttt tgcaaatggt ggtatttatc ataaaccaag gtatgtcaat
    29881 aaagtggaat ttagtgatgg tacaagtaaa acttttgatg aaaaaggaaa acgtgccatg
    29941 aaagaaacca cggcctatat gatgacagat atgttaaaaa ctgttctcac ttatggtaca
    30001 ggtactgctg ctgccattcc tggtgttgcg caagctggta aaacagggac ttctaactac
    30061 actgatgagg aactagctaa aattggtgaa aaatacggcc tttatccaga ttatgttggt
    30121 acattagcgc cagacgaaaa ctttgttggc tttactaagc gctacgccat ggctgtttgg
    30181 acaggttaca aaaaccgctt gaccccagta tacggatcaa gtctagagat tgcatctgac
    30241 gtttatcgta gcatgatgac ttacttaaca aatggttaca gtgaagattg gacgatgcca
    30301 aatggtcttt atcgcagtgg tggattcctc tacttaagcg gaacctatgc gagcaacacc
    30361 gactatacta attcggttta caacaatctt tacagcaata acacgacaac agcttctagc
    30421 caaacgactt cagatgatac tagtagtagc aatgatataa gtaattcaac caatacagac
    30481 aacaatagca atcatccatc taccgatgat aaaaagacaa ctcattaatc tctaactcta
    30541 cttattgtct gtacctacct tttattacat atccatttag ttacttttaa tatctacctt
    30601 aagtgataat ctaaataaaa agcgagttca cgttctgtga ggactcgttt ttatatgaca
    30661 caaatgactt accacataca atataaaaca aaaaacagaa ttctttaatc gtattaaaga
    30721 aaaggtacaa cgttaagggg attagcaact gatttttcaa acgttaacct aaaacaaaat
    30781 agacttattt aaaattgtta taaatagcaa cctaatgcca taagagagta aacatgaaaa
    30841 aacacgtttc catataccga agacgtgttt tttcatatgt cattttctta gcataataat
    30901 ttttttcatg ttcactttct tatgcggagt ccaatccgtt tgctgttcgt tttgtccagc
    30961 ctttagattt catacagtcg caaagaaagg aattagcatt gtgctaaagc acccattgga
    31021 tcccaaggag ctagtacttg tggctctttt tcataagccg ctaactcgtc agctgttaag
    31081 aattctttac ggacaacaat ttgataggta tattcatcca tccaagcatc tgaagcaaca
    31141 aagtaacctt tgtcaccaac cttctcaccc catgaatttt caaccttcca ttttaacggt
    31201 tttcctgttt catctaagtc aacacctgtt aaaaccatag catgtgtcat caaactttca
    31261 ctataatcca aacgtccagc cttatcttga ctaagattga tatccatact agcttcaaaa
    31321 tcgtaagtat tagttgccaa aatccctttt tgacgatctg aaacttgacc cacatcagag
    31381 ccaaaccaaa cggactcacc agcctgcatc tgcttgatag ctagttcttt gaaacgtttc
    31441 atatcaaggt tgaggtagcg aacctcacga ctaccgacca catttcctag catctcaaca
    31501 gtgtatgatt tgccataagg cttatcagca gttggcgcat taataacaga cacataatca
    31561 gaaagcttta agccaacaaa tttgtcgtaa aacgcttgcg gtgtcaaacc tttctcaaca
    31621 tgatagtggt catctttatc acggtaggca aaatcaaaat gacgaggtgg taaaccaagg
    31681 gtcatggcca agaagttaaa aatttcctga agaagctctg cttttcgatc ctcaacttgg
    31741 tctgccttag cacctgacgc aatcaggtca cgaagaattt gagcatcttg gcgcaataat
    31801 ttattcaaat actggtttaa ttcacgactg ttacttgatg agattgattc tgggtaaaca
    31861 gattttggca ccactccata cttctcaaac aaggaaacta ccatgtccca ctgaccacca
    31921 tcttgttgtg gaacatccaa gagaaactta actttacgac tggttaattc ttggtcagct
    31981 gtagcaatga cctgctccat aaaccagtta gctttttcat acttatccca aaagaaagta
    32041 tgagcttgtg acagttcaaa attttctaat ttaaactctg tgattaattt gtgtcggaaa
    32101 gtgttcaagg cagcaaacat ccagcaacga ccagaagcct tttggttaga taccttatct
    32161 ttagttaaat caatagaaaa cacaaaatca ttgtccactt cactttgacg ggtttctaat
    32221 gattttagca aaccattatg cgtaacggca ttctcaatag ctgaaaattt tgcactggct
    32281 tcgtaatgag caaataattg ttctgtaaat gtctctgtta atgctgacat tattgtcctc
    32341 ctaaaatatt aagataagct tcacctgaaa taatattggc aagatggtta ttatccagcc
    32401 attctattct aaaggattac ttctattata gaccttattt gattttcttc aagaaaaaag
    32461 ttaggataac ctaacttttt ttgttttctt tttttactct ttgaacatca tctcttattt
    32521 ccaaaaatca tcaaaaatgg tgattggcag gtgacgcttg tgttgtcctt tatgccacca
    32581 tttttcaata gttgcttgag ctactttgga aatcagcttc ccttccaaat agtcgtcgat
    32641 gtcttgatag gtcaccccta gagcaacctc atcagccaag cctggttttt gatcttctaa
    32701 atcagcagtt ggaacttttt catacaaagc agcatctgct cctaaaactt tcaaaagagc
    32761 ctttccttga cgtttgttaa gcctaaagag gggaagaata tctgctccac catcaccaaa
    32821 tttagtaaag aaaccagtga tgttttctgc cgcatgatcc gttccaataa cagcaccagc
    32881 catttggcca gcaatggcat attgactgat catccgctga cgtgctttga tattaccttt
    32941 gttaaaatca gaaatctcaa cgcctgctgc ttgtagagcc tctacttggc catcaacagc
    33001 tgctttaata ttaatagtca gtgtttggtc tggcatgata aaagccaagg ccttttgcgc
    33061 atctgcttca tcagcctgaa ccccgtaagg caagcgaaca gctataaatt ggtaagcttg
    33121 atcacttgtt tcctcccgta actctgcaat ggccatctgg gctagctttc ctgcgagggt
    33181 agaatcctga cctccagaaa tgcctaagac ataagttttc aaaaataagt gcttacgcag
    33241 ataagctttt aaaaaatcaa ctgttttccg aatttcttct tgtggggcaa tgctagcctt
    33301 gacgcctaat tgtcggataa tctcttcttg taaggtcatt ttaaatcact ctttccatga
    33361 gtatctttac gaatgttatc aattaaggcc atcttatttt gccaaacatc tcgtgccaag
    33421 tctactgggt agtcttgagg atttaagaca cgcttgtatt catcccaaag cttgtcaaat
    33481 tcttttttag cataagtctt gatttcagat aaggtcggta gctggtaaac taattctccc
    33541 ttgacaaaaa tatcaactaa gagaggaatt gcatcaaaat ttctgacggt tttcttaata
    33601 taggtatagg tcggatggaa catctcaatc tcagttaatt cattaacatt aatatcagta
    33661 aacgtgatat agtcgccttc tgatttgcct ttttcacgac tggtgatgcg ccaaacttgt
    33721 tttttacctg gtgtggatac tttttctgca ttatttgata atttgatcgt atcacgcatg
    33781 ctaccatctt cttgctcaat agagacaatc ttataaacag cacctaaggc aggctgatca
    33841 taggctgtga tcagtttggt cccaacaccc caaacatcaa ttttggcctt ttgcattttt
    33901 aagttgagga tggtattttc atcgaggtca ttagaagcat agatcttagc ctcggtaaaa
    33961 ccagcgtcgt ctaactgctg acggactgtt tttgagaggt aagccaagtc accagagtcc
    34021 aatcgaacac ctagaaaatt aatcttgtca cccatttctt tggctactcg gatagctgtt
    34081 gacacaccta ctttaagtgt gtcataggta tcaacaagaa acacacaatc tttatgggtc
    34141 ttagcataag ccatgaaagc atcataatca ttaccatagg cttgcactaa agcatgagca
    34201 tgcgtacctg aaacagggat accaaagcgt ttacctgctc tcacattact tgttgcatct
    34261 gctccaccaa taatcgctgc gcgggttccc caaatcgcag catctagttc ctgtgcacga
    34321 cgggtgccaa attccaaaag gggttcatcc tcaatcacag aacgaatacg agcagccttt
    34381 gtagcaatca aggtctggaa gttaacaatg tttaaaagag ctgtttcgac caactgacac
    34441 tgacctagag ggccttctac ttgcacaatc ggctcattag caaaaaccaa atctccttct
    34501 ttagctgaac ggatggtcaa ttctaatcgt aactctttaa ggtaggtcaa aaagttttct
    34561 ggataaccca gttcttcaag gtaagccaaa tctgtttctg aaaattgaaa ttgctctagg
    34621 tactccacca tgcgctgtaa accggcaaaa acagcataac cattgttaaa aggttccttg
    34681 cggaaataga cttcaaacac cgcatgacga ttatgaatgc cctgctcaaa ataaacttgc
    34741 atcatattaa tctgatacaa atcagtatgg agagttaaac tatcatcttt atacataaag
    34801 gggactcctt tgaattattg ttactattat aacatatttt aaaaaggact ctttggctag
    34861 gatttagaaa taacttgagt tatcgctaaa gtaaaaaaga accgatccat cataacatcc
    34921 tcaaataaga aaaagttaat ggattcagtt ctatatcgct aattattatt taaatttgac
    34981 attgctataa atcccaaaaa caataatcca aatcgttgct ccaattgcgc cgatataggt
    35041 ggattcttgt aagaaaagag agataaagac aaaagcaaag aaagcaaggg tcaaaggcgt
    35101 tgtcacttta tattttggca tcaaataacc atctgccata aagtccttag attgacggta
    35161 cttccagtga gcaatcatgg ttaaggcgta gatagcaatg tatacacctg atgaggaggc
    35221 cgtaatgagt gagaacgcat ctgcaactcc tggcaaaata ttaatcaaag ctgagatacc
    35281 aaccacaacc gctgaagcaa taatggcacg acttggcacc ccttgtcgag ataaagtatt
    35341 aatctttaag ctattggtca aagcgtttgg agtctcatta gcaatctgat agagatgacg
    35401 accggttgaa taaagggttg agttaagcgc tgacgctgct gatgtcaaga ccacaaagtt
    35461 aatcaaggct gctgcccatt taataccaat caatttgaac accatcacaa aaggagattc
    35521 atcaactggc aactgatgcc atggcacaat tgccataata gagaccaagg ctcccacata
    35581 aaagatcaca atacgggttg gaatttcttg aatagccttt ggtagaactt ttcttgggtt
    35641 agccgtctca gaagtggtaa tccccacaaa ttcgatagct tgataagcaa agaaaaccat
    35701 ttggaaggcc ataaagaact ttagtttccc atttgggaac atggaaaaat ggtcaaaaat
    35761 attggaaagg ctagcatggc ctgtgtgagt ttcaaaacct gtcaatacca tgaaaatagc
    35821 tgttgcaatc aaagctaaaa tagctaaaat cttaatcatg gcaaaccaaa actctgtttc
    35881 cccaaaaacg cgcacagcaa ttaagttgat cgaactaagt aagactaaga aaaccaactg
    35941 aatcaaccag gctggccagc ttgggaacca aaattgcaca taagcaccta ctgctgtgat
    36001 ttctgccatt ccaataaaaa taagggaaat ccaataggat agacccgaaa aataacccca
    36061 gcctggacca atgtatttgg aaataaaatt gataaaggtg tgttgatctg gatcataata
    36121 gagcatttca ccgatggcac gcatcatcat aaacatgaag gcacctgtaa tcatatacac
    36181 aaaaataata gatggtcctg ttagggcaat agagcgtcct gcccctaaaa agagacctgt
    36241 tccaatcgtt cctgcaatcg caattaactg cacatgacga ttttctaagc cccttaccat
    36301 tccattttct agttcgttat tgtctgtttg ttcttttata gacattctaa actccattca
    36361 ctaaaatact atttattata tccttttttc agaaaatttt caacatttat ctaggaaaga
    36421 tattaaggaa aactgttctt tatatttctt aaaggtctta tgcaatttag cttttttaag
    36481 ggaaagacaa ggaaaaatga aggagtttta accttatgaa gggaaacttt caaggtagtg
    36541 ataaacacct tgccctgcaa ttgcaccatc tccaacagct gtcgtgattt ggcgaaggtc
    36601 tttttgacga acatctccaa tcgcaaaaat accaggaata cttgtcctca tatgatcatc
    36661 tgtgataatc caaccttctt gatcggtaat ttctagatcc gttaccatac ctgtcacagg
    36721 aatcatacca acatagataa acacacctcc aaaagcgtgg tcagtgactt ggcctgtttt
    36781 cacattttcg attaggacat tggagacctt aatgtcgtta cctttgattt ctttgacaac
    36841 tgaatcccag ataaagtcaa ctttgtcatt agcgaaggca cggtcctgca agattttctg
    36901 agctcttagt tgatcacggc gatgaacaac ggttaccttt ttagcaaact gagtaagata
    36961 aatagcttct tcaactgctg agtcaccacc accaacgacc aaaagatcct ggtcacggaa
    37021 aaacgcacca tcacatactg cacaataaga aactcctcga ctagtatagt attcttcacc
    37081 tggaacacct agtacacggt atttagctcc cgttgcaata ataaccgttt tagcttcata
    37141 actagcatct tcagtcgaca cacacttata gtcaccaaaa ttttctattt tttgaacaat
    37201 accataaatg ttttcaacgt taaacttctc taaaggttcg tacattttca tagctaattc
    37261 tggtccagat atatgatcat atcccgggta attctctata tcaaaagtgt tgttcatctg
    37321 accaccaggt gccccttgtt caataatggc aacagataaa ttacttctag cagcgtataa
    37381 agcggcagtc attcctgctg gtcctgaacc aataattaat gtatcgtaca tgatttttct
    37441 cctttaatct actcttgcca atattttagc aatgataatc ccttcttgca atgattagga
    37501 ttttatgaca accaaaatac tcataaaagc aaacgataaa attgggatgg ttaaaatagc
    37561 aaccattagc atctcataaa gaaaagcttg tctttcaatc aatgttttat ctcttttggt
    37621 ttttgctcgc cataaagtcc atattaaaca aattaacatc atagtaaggc ttgagagaat
    37681 gagacctttt acataaaggc taaagatttc tactaacata tttccaccta gtcattattt
    37741 ctttcccata agtttttcta aaaaacataa caagaaaagc ccaggaatac ctagaccttt
    37801 ttattataac aaaagaataa cattaaatgt atgtttttga atagcttgca aaaaattctt
    37861 tggttcgttc tttttgagga tgtctaaaga cttcttcagg tgttccttgt tccaagattt
    37921 tcccttgatc taaaaagagt actctatctg ccacttggta aacaaaattc atgtcgtgac
    37981 tcactaaaac catggtctgt ccggatttag cagcatcagt aatagacttt tccacttcgc
    38041 caactaattc cgggtcaaga gccgaggtcg gctcatctag taataaaaca tctggtttca
    38101 tagccagagc tcttgctaaa gctacccgtt gtttttgtcc ccctgataaa tgacgtgggt
    38161 aatgatgttt tcgatctgct aaaccaacct tagccaattc tgcttgcgcc agtttagtcg
    38221 cttcttggtc agacagtttt ttgaccacct taagaccttc tttgacattc tcaagggctg
    38281 tacgacgctc aaaaagatta aattcttgaa aaaccatggc aagtttccga cgtaaaataa
    38341 ggacttgctc tgtggtaatg gtctcaaaat caaccgtaaa gtcaccaatg ctaatggagc
    38401 ctgaatctgg tttttccaaa tagtttaggc tacgaaggaa agtcgatttc cctgctcctg
    38461 aagcaccaac taaagcaatc acttgacctt tttcaatatc aagagccaaa ctatctaaaa
    38521 ctttttgctc tgagaatgtc ttgctcaaat ttctaattgt aatcatcaac gcaattctcc
    38581 taacttttca tttctagctt gttctggtgc tttgatggcc atcttgtttt caatcaagcg
    38641 acctacttgc tccatcaaaa tactgataga ccaatagaca agagcaacag agatataacg
    38701 ttcaaaataa cggtaatctg atccgcctag aatttgagcc tgggcaaaca tttcgacaat
    38761 ccctgcatta aaggcaagcg atgttccttt agttaagcca attaacccat taatcaaggt
    38821 tggaatagcc acaacagttg cattaggaat aatgacacga cggtaaacct gcacagaagt
    38881 catgcctaga ctttttgctg cttcaatttc acctgtatct actgataaaa tggctgcccg
    38941 aatagtttca ctagcgtagg ctgcttcatt aaaagcaaag gctgtaatgg caaaaataga
    39001 agccggaatt gcattaacat tccaatcaaa gccatacttc tgattgagac attttagaaa
    39061 gaggggaata ccgtagtagg tcaacatcaa ctgtaccaaa ataggagttc ctcgcaagaa
    39121 actcacaaaa atagcttgaa tagggtatag tagcttcact ttattaattt tgacaagggc
    39181 aaaaatcaaa gccaaaacca agccaaaggt tgctcctgat agtgtcaaac caagcgtaat
    39241 tggaagccgt tggataatat ttggaatggc atcaaaaaca gcatgccaac taaaaagttt
    39301 cccatgtgga atcggtgaga tgaggtgatc ataaaaagcc caaccactgg ttaaaaacac
    39361 tgatgtcatg tatttcccct ttgtatttgt ttgtcttaat attctaacac tcttagatcc
    39421 acatgtaaaa tagtaaatcc gtattatagc aataagcaaa agctatgatc actttttgtg
    39481 ttaacaaatg gtaaacaata caagtagcag gtgtaaaaaa agcaagatta gatgccaatt
    39541 gatcacttgc ttgctctttg ttcttaaaaa tgttgttttt tggccttacg ctcagcgcgg
    39601 cccttagcac gattttcagc acgacgttct ttgcgacgtt tttcatcaac cgcccactga
    39661 atttttttct tgtaacctgg tttgactttt ttctttttct ttttgaccaa accaatcatt
    39721 tctgtgtcta atttttgata ggctttttca cggttttgac gacgatcacg gtcataggta
    39781 tcttgaaatt ctccattttt gagcaccttc ggtgtaaagg caatccccat tttttccagc
    39841 tctttgatat ctgagtcgtc acttggctgg taaagtgtaa tggcagttcc tgccatacca
    39901 tttcgacctg ttcggcctac acgatggaca aagaaagaca agtcttgtgg gatggcgtca
    39961 ttgatcacat ggctgacccc ttcaatgtca atcccacgcg ctgctaagtc tgtggcaaca
    40021 atgtattcaa agtccagttt tttgacttgg ttcatgatgc gcttacgttc tcttggagga
    40081 atgcccccat gaatcttagc cacttttaag ccattagctg ttaaaaaggc atgcaaatca
    40141 tctgcgcgtt ccttggtatt gacaaaaagc atagccatat aaggctgcat ggttttgaga
    40201 atctctaaca gttgaccatt cttatcacgc ccttttgtcg acacaagcca gttatcaatg
    40261 gtatctgcga taacggtctt tgtcttgatt tgttcaataa caggattggt caagtatttt
    40321 ttcaaaaagg gttgtaattt ctgtggaata gttgctgaga acaccaaaat ctgaacagat
    40381 tttggaagag aggctgcaat cttatctacc gtatccaaaa agcccatgtc catggtcata
    40441 tcggcctcat ccacaacaaa ggtcgttgct ttatgaatcg ctaaatcacc agacttgacc
    40501 aagtcataaa tacgacctgg ggtcccgatg acaatatgcg gctggccgcc ttttagtttt
    40561 tcaatctgac ggagtttgtc tgtgcctcca acatagttgg ccaaacgaat ctcttcttgg
    40621 gagtgcttag caatctgttt acaagcatca aaaatttgag ttgctaattc acggctaggt
    40681 gctgtaataa cgacttgcac ttctgcttta gcttcatcaa gtttttcaaa aatgggcaac
    40741 aaaaaggtgt gggttttccc tgaacctgtt tttgattccc caactaagtc acgaccggag
    40801 ttaacaatag gaatcagccg cttctggacc tctgttggat tgacaaagcc aatttcttcc
    40861 agcgcttgct gaacgtattg cttaaaatga taatctttaa atgacatgtt ttacctcgtt
    40921 ttcttccata ttatatcatt attgttagag acaagcaaaa ggagtgggac aacactcaca
    40981 aaatcagcat ttgtgggtca tctccactct cttattgatg atgttaatca aaatgctatt
    41041 ggtgactatt cttgataatc ccccttagaa cacgtataag atagctaaaa ctagtaaact
    41101 agctagactt cctactcccc acaaaaaagc atctacctgc cattctgacc acttcttgcc
    41161 tttaccagac aagcctccca attccaaatg gtggtggaaa ggcgtcattc taaaaatacg
    41221 acgaccttct ccatattttt tcttggtgta cttgaaatag gacacttgca acatcacaga
    41281 acttgtttca agaacataaa cgatcccaat aatcaggaga gtccattctt gacgaagcgc
    41341 aatagaaatg gcagccaaca tagctccaag ggctaaacta cctacatctc ccataaatac
    41401 tttagcaggt ttgtgattaa agcagaagaa gccaagcaag gctccaatca ttgctccaat
    41461 cagtaacaaa acatcaaatt gactctgaac gtaggcaata acgccgtaag tcactagact
    41521 aatcaccact gagatagaag ctaagccatc gataccatct gtcaaattaa cggcatttga
    41581 aaaaccaacc acccaaaaca aaacaaagaa tagatagaaa attcccagcg gcagctgata
    41641 accaaacaca ttaatagagg aaatgccact tggactaaca tgtaaaaaat agaacatcaa
    41701 tcctccaacc aactgcaagg ctaacttttg tttggctgtc aatccttcat tgatttgctt
    41761 aaaaattttt aaaaaatcat ccaaaaatcc gataatcccg taaatgacaa caattgataa
    41821 aatgcctgaa atcaaagcta aactttgagt gtttttgatc gaaaatagac taaccaataa
    41881 cgatactgcc gtagctacta aaagaaaaac agttcccccc atagtcggtg ttccagcttt
    41941 agctaaatgt tgcttgacat cttcatgcat ttgttgccca ccaatttttt tcaattgata
    42001 gaatttgata aaataaggca ttgtgaaagc agataccata aaggatatga ttgctgcaat
    42061 aagggttaaa aacatgttaa tctcctaaag taatggtcat tttttttatt tttttcaagg
    42121 acttaccaac atcaacactt tgtttcataa cacgaccaga atctgttcct ttaaagctga
    42181 tgtctattcc agtccattta gcaaaggttt taacattgga ttttgtccag ccatacatgt
    42241 ctggtacctc cacaaaacgg tctgataata tgagaacttg ttggttttct gttaacgttt
    42301 gaccgggctg atgcgatact tttttgatct tgctgccagt accaaggaca actggctgga
    42361 caagatttcg acgcaactcg cttgatgtct caccaggatt ctttcctaca aagtttggta
    42421 atttataagt tgtttgacga ttagcatctg atactactgg cttagttagt gtatcttgca
    42481 ttaagtatgc ttcttccaat actgggttaa ccacatcttg ccaaaaaagg ggaccaaaat
    42541 gttgtggttt agtcatagta acatacatca aaaagtctgg tttatcagct ggcaccattg
    42601 ccacaaccga ataaacatag ttagtcaatc caccatcttg ataaccactt ccatcttctg
    42661 aaccaatttg tgctgttcct gatttaacag caacaggtaa atcacccact ttaataattg
    42721 gtccaaatgt ttttgaatag agtgttccaa actcagggtc tgttcctaca ccaatcatgt
    42781 actgtcttgt ttcactagcg gctttttttg atacaggttt tccaacaatt tctttatttg
    42841 ccgttctaaa acttgctgtg ttaggatcat aaatttgact gataaattgt ggctctaaca
    42901 tctcaccatt attagaaata gcagtaaagg ctctaagcat ttgaatctgg gttacagaaa
    42961 tcccttgacc aaaagcgctc atagcttgag tcacgatatt atcagaagga aatatacctg
    43021 cgtcttcatc ttttaaacca aaacgagtag gaaaaccaaa gcggaacttc gtcaaataat
    43081 tcatccattt tgcattaccc attttttgtt caagtttagt catcccaacg ttacttgaga
    43141 aggcaaaccc ttgtgcataa ttcatgtact gtcctgtgga aatgccttcg ttaatagacc
    43201 agtcttgaat agtagcatct gcaattgtta aaccattagc attgctaaag gtttcgtttg
    43261 ggttgaaaac tttatcatca atagccgctg ccagagtcat cactttcatg gttgagcctg
    43321 gctcaaaatt tccttgatga agtgcactgt accatttgta gttcgtattt tcaagtcctt
    43381 tcagagtatc agcattataa gtggggcgtt gtgttgttgc caaaatttca ccagttttag
    43441 cattaacaag tgttgcactg gccaactgac catttgattt ggcttgaaaa acatccatct
    43501 gggtttctaa gaaggtctgg ataggctcag atagcgttgt gtaaatatct ttgccatcaa
    43561 tagctttctt gacagtctta cctgtaccca agagtgtggt cccatttcga tctttttgat
    43621 aagtaataac accatcttga cctgataaaa ttttatcaaa agaagcttct agacctgttt
    43681 ttccaactaa actcttaaca cctgtctttt tatcttctgt tagagatgct aggcctataa
    43741 attctgaagc aaatgtccca tttggataca tacgaccagg actagttgtg aaagcaattc
    43801 ccttgatttt ggcatcttcc atagcctttt gaatagtaga catagtacta tatgaaatgc
    43861 cagaccctga cggtccaaac gagacttgga aaagtccttt acgcttaagc tgtttaatta
    43921 catctgtttt tttcattccc agatgctttt ttaaaatatc agctactgtt tcatactgag
    43981 aaggttgtac atataacttt tcatctgaag ccgagacaaa tgatttatcc aaaattgcgt
    44041 atatgctata agtcgtagaa tccactgcaa tagctgtacc atttcgatca taaatggtcc
    44101 cacgcttagc ttggatcgta acggtttctt gataaacctt cttcgcccct tctgacaaac
    44161 taactccaaa cttttgatct gttccaataa taatcatgaa attaataatg aaaataaaga
    44221 aaataaagat agttaagagc atcatatttt gtccaactcg aacgcgattt tcgactggag
    44281 ttctcctatc gcgcacaaca taatctaaaa catatttttg ccattttttc atagattact
    44341 cgactttctt gatattatta ttacggttgc ttaagcctgc tttaccagca atatctataa
    44401 tacgatcacg gcgagataac tcatttactt cttgcttggc attattaagc tctagttttt
    44461 gatccgaaat atgactattt aaactagtga tttcttgttg tagctgcaac ttacgacttt
    44521 gcaggtaaat aatacttact gccatcgtaa tcgctgttac aatgatagca gtataaaaag
    44581 ccttctcaat tctagagaaa gtttttattc gtttttgcaa ggcatttgta actgcctgag
    44641 ttcttttttc atttgtcata ggcttatttc cgaatttttt tggcaacacg tagcttggct
    44701 gagtgtgccc ttttattagc tgttaactct gaatgactag gtaagatcgg cttacgtgaa
    44761 acaagttcaa acttaggttt catatcttca ggaattagag gaagcccttt tggcacatcc
    44821 accgtactag cttctttaaa caactgcttg gttaggcgat cttccagaga atggaaggta
    44881 atgactgaga tacgaccatc aagggctaat aattccatag cgtcctgaat agattcatca
    44941 gccgctccca attcatcatt gacttcaatg cgaatagctt gaaaaatctg tttagcagga
    45001 tggccttttt tcttcaactc tttagctggc tttgctgcct taatcaattc tgccaactct
    45061 gttgttgtct caataggctt aatagctctt gcttgttcaa tttttcgagc gatctgcttg
    45121 gagaatttat cttcaccata tttgaaaaaa atcttaacca aatcattgaa tggataggta
    45181 ttcaccactt cgtaagctgt taagagcgac tgacgatcca tgcgcatatc caatggagca
    45241 tcttgtttat aagaaaaccc tcgttctctt tcatccaatt gcgggctgga aacaccaagg
    45301 tcgtataaga taccatcaat ttcatcaact ccaagcgctg ttaaacgtgc tttgaggtgt
    45361 ctaaaattat ctttaataaa agttacctgt cctttgtcaa tataagattt gagggtaact
    45421 tgtgcattgt caatagcctt ttggtcttgg tcaaaacaat agaggtgccc ttcttcacca
    45481 agtttggaca acaaataagc tgagtggcct gagccaccta gcgtcgcatc aacataaatc
    45541 ccatcaggct ttatgtcaag catgtccact gtttcgtgaa ggagtacggt cacgtgatga
    45601 aattcttttg tcataacttt aattgtacca tacttcaaaa ggtttagaaa tgaaaaagta
    45661 agagaaaagg atttcattct cgtgggaatc ttcctcttct ctaatcttgt tctttttgtt
    45721 cgctatcagc caacttagca agcactgact tagccgctgc ctctagaatt tcaactgctt
    45781 gtaaaagatt tttagcttcc ttaatcacac accaatctgt cagcaggttg tctaaccaaa
    45841 taccaaaggt tttatcccaa ctcatatttg gtaagtcagc taataatagc ctatcgacgt
    45901 ctgccagcta tcttcggcag ttttgaagag taacttgtaa gtctattaat aattgtttaa
    45961 ccttgctcac gacgtttgat ccagctgaca agcataccgt ctccaaaaaa acaaaatagc
    46021 cccaatttcg gacaattttc aattccaaat gaatcacctg aatctgatgt aaaagttctt
    46081 ctaaagcaac ctttgcttct tctttttctc tttcattagt cattaaggga ccttctagta
    46141 gcttattctc tgatatgtcc atccccatta atataaaatt tagtgcttgt caaggcttct
    46201 aagcccattg gcccacgggc gtgcattttt tgagtagaaa tcccaatttc agcaccaagc
    46261 ccaaaaacaa aaccatcggt aaatcgtgtt gaagcattga cataaacagc agcagcatcc
    46321 actaaatctt gaaaggtctc tgctgcctta atatcccttg tgatgatagc ttcggaatgg
    46381 taactagtat gctgatttat ccaagaaata gcttcttcca aagaggaaac aaccttaaca
    46441 gacatgatat aatctaaaaa ttcggtctca aaatcctctg cttttgcagg cactgcctgc
    46501 tcaaataacg gcaaagcctt gtcatctgcc cgccattcta ctggctgaac ctgattgatc
    46561 gctttttcaa gcataggaat aaaccttgct gctacagctt cgtgaattac caatccctca
    46621 gctgcattgc aaacacttgg gcgccttgtt ttagcgttga taacaatctt agtagccata
    46681 tctaagtcag cctgagcatc cacatagata tgcacattcc ccacacctgt ttcgatgaca
    46741 ggcacttttg ctttttcctt aacggtctga attaatctag caccaccacg tggaatcaaa
    46801 acatctacat aatccgttgc ctgcatcaat tcttcagcaa cagcatgtga gggatcctca
    46861 actagctgga cagcatctgg ggtgatccct gatttttcca gactttgtcg gatcaacttc
    46921 accaaagctt tatttgagtg aagggcatct tttcctcccc ttaggatgat ggcattattg
    46981 gttttgaacg ccagactaaa agcatccact gaaacattcg ggcgactctc aaaaatcatc
    47041 gcaatcaccc ctagaggaac tctcttttgg aggattttaa ggccatcgag gttagtatag
    47101 cccttaatga cttgtccgat tggatcagct aagtcagcaa cctgttgaac tccctgtgct
    47161 atcgctttaa tccgttctga agttaagcgc aagcgatcca tcatgatgtc agaaatacca
    47221 tgttctttag cattcgctaa atctttttgg ttagcggcta agagagtctg tgtatcgtca
    47281 actaatgcct ttgctaaggt gcttaaaaag cgatttttaa tttgcgtcga caaaggtgct
    47341 attaaaagac tagcttgttt tgccctttgc cctaaccttc tcatatcagt catgtgttac
    47401 ctcttctatc tgcttgaacc aggtgcctag tggttgccct tcaagcactc ttaaaatatc
    47461 tctgggatta gctccattca tcaagaccat ctgtcctttg ttttcaaata ccatctgagc
    47521 agactgaatt ttgctaagca tcccacctgt gccaaattta ctgcccgcac cacctgctga
    47581 cgcaatgatt tcttgcgtaa tgactgcaac atggctgcgt agctgcgcat cctcataaat
    47641 agtagggttt ttatcaaaaa ggccatcaat atcagacaac atgattaata aatcagcttt
    47701 tgtaatacca gcaacaacag cagataaacg gtcattatct ccaaatttag tcgcatgatc
    47761 catttcatcc acactaaccg catcgttttc attaacaatc ggcacaatgc ccaaactaat
    47821 cagactttca aaagcattgg taacattggc tagactttct gggaaaacca ccacatctct
    47881 cgtcaataaa atttgtgaca cgttggtttg gtagtgtgca aaaatttgtg aataaagact
    47941 catcatggct acctgaccaa cactggaaac tgcctgttgt ttagcaagat tggtcggacg
    48001 tttttccatt ttcaaaatat ctagtccaaa tcccatcgct cccgatgata ctaaaataac
    48061 ttccttgccc ttattcatca aacttgaaat cacaaaagcc agttggtcga ttttttctaa
    48121 attgatttta cctgttggta gcactaatga actagtgcca attttaatta cgatacgtgt
    48181 tacatcttca aattgtcgtt tcatcatacc caaattatag cataaaaaac agccccagag
    48241 gactgttttt ccgaataatg atccctcttc gttaaagcct ctctaagctt ttccagaagg
    48301 ttttttgaat ccataattgc gcaagaccta aaaccattag tattagacaa ctcaatagaa
    48361 tactaatcaa cagaggttgt tggataatat tggcaatgat aacagctcca aaacctagca
    48421 cacctgcaac tattaaatta ccaaagataa gtcccattgt taaccattgc ccatctcctc
    48481 tggtaaagag ttgcgtcatg tcttgccatt ttatatccag aagccggtag tcacgacgat
    48541 acatcaattc cccttgcaca atcagtgata gggcgtagcc aagacaaaaa gcaatcgtta
    48601 gcaggggatg gaggtgcaac acaaagagac caaacacaag ataaatcacc ataggcacaa
    48661 tcagttgcag acctacaagc aagcaaaatt tatccagcaa gaattttttt aacgttattg
    48721 gtaagctttt aataaaggta aagttatcct tttcaagtga aatacctact ccaataaagc
    48781 tggttggtgt tgcacacatg acacccaaac taaccccaaa taataaggcc accccaaagt
    48841 aatctgggga aatatgctta aagaaacctg tgccacgtga caaacttgga ccgataaaaa
    48901 gcatcacata catcaggggc atgagatagg tttgtgtcag taaagttgca ttttgtaacg
    48961 ttaataggtg atgttttcgc aacaactgcg ccagtgattg attctgatga ggacgattaa
    49021 ctggtttttt agtttgcttg actttgttct cgttactaat ataaaaaacc tcacgataat
    49081 aagttggcat cacttttgtg acaataccat ataccatagc taggataagt aacaatggga
    49141 accaaaagtt aaggagggcc acagtagaaa acggtgcctg aacaacatca tagaatcctt
    49201 tgaaatacgg aatagttggg taatcagtaa atacgccatc cgtcatcgta cgcttgttgt
    49261 tactaatatt aatcgcaaaa attaagacga aagctccaaa agttgagaca aacatcatga
    49321 tagttgaaat gagtttccgc ttgcgactcc ttacaatgat tttgcccacc caagcattga
    49381 tataaatagc taataccatc gaactcacta gtaacactaa aaagagcacg atagctacta
    49441 aaatagacaa aggatttccc aatagttgcc agtaggcaat taagagaaga gagataagag
    49501 gcatcaaaaa gacagcaccc atccctagcg acgagacaat ttttgcaata tagagttctt
    49561 ctgacgttac tggtaagtga atataaagtt ttaggtcatt actttcataa aaaatggtgt
    49621 aaagagagct aaaggctgtc aaggttgaca tgataaaaaa catagcaacg tcaaaggaga
    49681 aaagtcctgg ataatgactg aaatcaacac caataaacat aaaaaggtaa atcaccaaaa
    49741 acatggcaat cattaaggcc tgttgcctca tcatgctttt ataggctttg aagttttctt
    49801 tcgggtgttt ttcctgacgc tttttgaggt tagctaaact ttgtggattg gaataaagaa
    49861 tgtttatctt gataagttcc caaatagtag accaattcat cccatcaccc ctcttcttgc
    49921 gccttacgcc ctgcgagttc aaggtagatg ctctccaaat ctttgtcagg atggtgttct
    49981 tttaactcat caatcgttcc aacaaaaatc aatttccctt tttttagaat cccgatacga
    50041 tcacataact gctcagcgac tgatagcacg tgagtcgaaa ataagaccgt atgtccagaa
    50101 gctgcatgag ctttcatcat ttccttaagg tcaaaagaag cctgaggatc caaacctgtt
    50161 aatggttcat ccaaaatcca gatgttagga tttgatacaa gagcaccaat cacaatcact
    50221 ttttggcgca tcccatgtga gaaactatca atggtttgat taacttcttc ctttagttca
    50281 aaaagtgttg tcagctgtgc taaccgttct tctcggtcct catctgacac cccataaatt
    50341 ttagctaaaa actgccaata ctcatttgga gttagattca agaaaatatc aggagaatct
    50401 ggcacataag caatttgttt tttgatagct tctctatttt ctgtcagaag ttgaccatcc
    50461 acaaatactt cgccataact cgcttcgata atagaagtca aaatgctgat ggtcgtggtt
    50521 ttacctgcac cattatgtcc gatgaggcca aaaatttcac cgtcattgat ggtgacgttt
    50581 aaatcgctaa gagcttcttt gtcgccatac aactttgaaa cgtgtttaaa ttctatcatg
    50641 gtatcctttt tccttttctt ctctttttct ccctagactg atgaggcttc ctctaaaata
    50701 tacttttcca atgactgctt aaaacggcaa agcgattttg gaagtaaaat gtcattatca
    50761 agtaagtaat tatccacatc ttggtttagt tggtaggcaa caagaagtgg gttactgtgt
    50821 ttaattaatc tattagaagc tgctaaaagt agctgcgaca aggccacatt ttcacgattt
    50881 tctggataat cataagcgtg tctaatcaca tcgtataagc gctgtcgttt cttttccatt
    50941 tatactcctt tatttttgta cttttacgct aatacaataa caattaaatt ataattttta
    51001 tgaattgttt tgtcaatgac ttcttatcaa aagaagtgta ttaggcagtt tgaggaaaag
    51061 aaagaactgg gtattttatt ttaaaaaaac agagtaaatc aaatgattta ctctgtttgg
    51121 gatgtgtaac ctagagtgat ttgtataact cagttgcatt tgccacagtg aaaccatatt
    51181 cttcgaagat acgatttcct ggagctgaag caccccaagt gtcaatggtc aatgtttttc
    51241 ctgctaggcc gacatatttt gcccagccaa agcttgaacc tgcttcgata gcgagacgtt
    51301 tagtcacagc tgctggtagg atgctttctt tatactctgc tgactgttcg tcaaagatat
    51361 tttgtgatgg catagatacc acacgcacat gaatgccttc tgcttcaaga gcttcttgag
    51421 tatccattgc cagtttcact tctgaacctg ttgcaatgat gataccatca aggtcgcctt
    51481 tggcttctga taaaatgtaa gctcctttgt taagaccatc ttctgccaat tcttttgttc
    51541 cttcaagcac tggaaggttt tgacgcgtca atacaagcat agttgggcga tctgtttcag
    51601 caatggcacg tttccaagca gtatttgttt cgttaccgtc tgctggacga ataacgttca
    51661 agttaggcat tgagcgaaca cttgccaatt gttcaattgg ttcgtgcgtt ggcccatctt
    51721 caccaacagc gatagaatca tgtgtcatga cataaactgt tggcaaattt tggagcgctg
    51781 ccatacgaac agctggaaga agatagtttg agaagacaaa gaaggttccg ccgtaaacgc
    51841 gtgtcccgcc gtgaagggca ataccgttca tggctgcagc catggcaaat tcacgaacgc
    51901 caaaccagat gttacggcct tcgtagtgac ctggttggaa atctgtttca gccttaacca
    51961 tagtattgtt tgaagctgaa aggtctgctg acccacccca gaaagaggct acttgttctg
    52021 aaatttgttg gatggcttgt tgactggata cacgactcgc cattgaacta ccaagttcgt
    52081 gcgcttcaag ttctacttga gcagcttcgt tagtaaaggc tttttggtat tctgctgcta
    52141 attctggata ttctgcttca taagctgcaa acaagtcatt ccaggcttgt tctgcttttt
    52201 caccacgcgc ttgaagacct tgagcaaagc gctctgttac ttcagcaggc acttcaaaat
    52261 cttgatgagt ccattggtaa gcttttttgg caaaagcaat gccttctgct ccaagaggag
    52321 cgccgtgaac agctgaagtt ccttgttttt cggcaccaaa accaataatg gttttaactt
    52381 cgatgatggt tggtttctca gtttcagctt tagctgcttc aatagcagct gcaatttctt
    52441 ctaaatcgtt tccgtctttc acaaggatat gttgccaacc ataagcttca aaacgtcctt
    52501 tcacatcttc tgtgaaagcc atagaggttg gaccatcaag agagatgtcg tttgaatcat
    52561 atagcaagac caatttccca agttttaaat gtcctgccat acttgctgct tcttggctga
    52621 ccccttccat aaggtcaccg tcaccattca aagcaaatgt gtagtgatca acgatgtcaa
    52681 agcctggttt gttaaattta gctgctaggt gagcttctgc catggccata ccaacggcat
    52741 ttgcaatccc ttgaccaaga ggtcctgtgg ttgcttcgac accgtctgtg tggttcactt
    52801 ctgggtgacc tggtgtttta gaaccccatt gacggaagtt ctttaaatct tctacagata
    52861 aatcataacc tgctaaatgc aacaagctat aaagcatggc acttccatga cctgctgata
    52921 ggataaaacg gtctctgttt gaccaattac ggcttgtttt gggattgatg ttcatgaagt
    52981 gattccaaag aacataagcc ataggtgctg cccccattgg aagtcctggg tgtccagaat
    53041 ttgccgcttg aatggcatcc attgataggg tgcggacagt gtttactgcc aactggtcaa
    53101 ttgcatcaaa tgtcataagt aaaacctctc tgtttattac aactaaaatt aaacgttttc
    53161 tattgtctat tgtatcacaa aaatagacgt ttttttcaga aaatcctcta aagtttctaa
    53221 attcttttct gctagaaaaa taactaaaaa cgttatggaa taagctcata tcactttctt
    53281 tttgactatc aaataagaaa gcctgttgac acgttggcca cagactcttt agccttattt
    53341 tttaaaggaa gcccaatctt ccataaaggt tttcaaacca tttgtcgtta agggatgttg
    53401 cgtcatctta gcaaacaagg gatctggaat ggtcgcaatg tgtgcgccta atttagcaac
    53461 agcttccaca tgggctgttg tacgaatact tgctgcgatg atttctgctt ggaaatcgta
    53521 caagtcaatg atttcacgaa ggtcgctgat taattgataa gcatctgtgc caatatcttc
    53581 caaacgaccg ataaatgggc taatgtaagt tgcgcctgct ttcattgcca ttaaaccttg
    53641 gcttactgtg aaaatcaagg tcacattagt tttaatccct tcttttgaaa gaatgtttgt
    53701 tgcttttaac ccttctgtgg tcattggaat tttaacgacg acattgtcat gccacttagc
    53761 aatgcttcta gcttcttcta ccatagcatc tgctgttaac cctgtcactt cagcactgat
    53821 tgggccatcg acgatgtcac agatttcttt gataactgtt tcaaaatcac gtccttcacg
    53881 tgagataatg gttggattgg tggtgacacc atctacaacg ccaagttcat taatcgcttt
    53941 aatagcggct acattagctg tatctaggaa aaatttcatt tcttacctcc aaaaattttc
    54001 gattttgtta agctctattt gataagcttt ttcaaatcat ctacctttag actatcctac
    54061 tttattatta taaaagtgta acagtcttta gaaaagacca agtatcacac agttttgtgt
    54121 gcaaaactag acttagctgc tgggctgagt gagagttcct cttctcgtgt atttttttgc
    54181 tggaaaaggt ctttgagaaa agcttctaag gcagtgagtt cataggggga gctatactgt
    54241 tttaaccggt aatagggtaa atcttgtctc ggtaaacaga cagtctgata ggtaatcaga
    54301 caatcataaa ctttctgatg atcatagggc attaattgaa aatccctacg atgccccaaa
    54361 tgacgtctaa tggccaattc cgcaatggct gcttccacct tattttgccc caaggcaagc
    54421 cctactaaaa gaggctcatg gtggcgctca atggaaaaaa tcaacaatac taaaatgtcg
    54481 tcactcaact gctgactgaa atccgtttcc tgacccattt gcagcactaa atggtttatg
    54541 ataaccctta aaagcgctct tttatcttcg cctactaatt gataaaggta ttggctattg
    54601 gttggttgac taaggatagc tcctttaaaa aagtaagctt tggaaaaaaa tatccccaag
    54661 ccataaatga tttcctcctt tgtctgatgg ataatcacat gagccttctt taaaagccat
    54721 aaggcttctg aaatgtgatc agcaatagga cctccaaaac ccaaactata cttcatgctg
    54781 gcaataggaa gtagaggata agcatgcaaa aagacaaaga ggctcttagc ttcaaaagca
    54841 tcaaattcaa gggcatagcg tcttaagtaa tgtaaaagca tgctttctaa gcgcttaaag
    54901 aaaatattag atgtcataaa gtcactatct cttaaaaaat gatcattgta gcctttttga
    54961 aaggacattc gcgcttgcga aatcgccaac caaatcaata attgttctaa ggcttctgcc
    55021 gataatgact ggccaatcag ccgctcaatt aaggtagcca aatgcgaagc gtctaactga
    55081 ttgaccaagg cgtctatgcc ttgtctggtc aaggtatggc ggaacaattc aaaatagaaa
    55141 taacgccact gaagctcact tcccagttgt ctgccttgcg agagcgccag atcaaattct
    55201 gataaaagct ggttgaggtg agctagttgt ctgtttagag tagcttcact aaccatcagt
    55261 tcaacggata agttggtgat gttaaagtgt tcatggcagt acatgtaggt caatatctga
    55321 taggcaaccg attctttgag aagcagagct accaaatcct cccaatggaa ctggccattt
    55381 tcttttaagc tcagactgtc tttttctaaa agtaattgac aggctaaacc ttgttctcga
    55441 cacaaatgat ttaggttgtc aatgtatttt aatagggtca ctttagacaa gtttgatagc
    55501 ctcattaggt cttttagcct taacgtttct ttagcatgat aaagggtcac caagagacga
    55561 tattgagctt ttcgttcttt atccattaag tcttcaatct tcatggcgga gcctcttttc
    55621 aaataatttg agacaagctt catgaagatg ataagccaaa tcactgtgac cttgtaaaaa
    55681 gagaaaatct tgaaatgcta agtcaccgtc tgtaactttc agagccagag cctgacctaa
    55741 ttggttggcg atgacaagag cattggtttt ggataggagc tgagcgccta ttaaaatccc
    55801 atccgttttt ctagctatta atttcagcca aaagaggttt ttagaattcc cattttggta
    55861 caaatagcta cacgtatcca tataaagctc tgcttcttct tctgtcacac caacactcgc
    55921 gcgataataa ccaaagtgag aactacctaa taccttgacc gtctgtaatg gaggaatagg
    55981 atatccagct aaatgcagag ccagagcctg acctgtcttc attgcttggt taatcaaagg
    56041 tgtatagtaa tccattccca atataccaaa atgcaatgaa accatgtctc caatggcata
    56101 gatattagcc tggctggtct gtaagttttc attgaccaaa atggtcttat ccagagcaca
    56161 agccacttgt ccttgcaaaa ggtgtgtatt tggcctaaag ttaatggcta aaatagccaa
    56221 atcaccttgg aaggtgtccc cttgctcggt atgagcgaca acttttccct ctatctcatg
    56281 aatagccgta acacgcttat tattaataaa ggtgacatgg tgagtggaca tttctgccat
    56341 tacaggggct atcagttctg cgtcagtctg atagaaatct ggacgttcgg ctgcttcaat
    56401 cagtttgacc cgtttgcctt gtaaggacaa actgtaggca aggtctaagc caatcaagcc
    56461 ggcaccaata accaagacct cttggctagc ctcaatcagt tttaaactag cttggctttc
    56521 ttcataatat ttggttacca aaactttgtt ggtctgtgac gtctcaatat aatgagactg
    56581 ggggctagca cccatggcac aaacaagcgt ttcataacct tcttcaaaaa ctcgtccttg
    56641 actgtctttg agaagcaagg tgtttgaggg agcttcgata gctaacactt ctgcttgaat
    56701 aaaccggtag ttagattcta tttgtgctgc taggcaggcc cttccccaca tagcatcaga
    56761 caggtcttga atgtctcctc tgaataattg gttgatacca tttggaatat aattaggaca
    56821 gctttcctta tcaatgagaa tgatttggga atctggatta aggtccttat atttatcaac
    56881 aaaggctaga ccagcaaagg atgccccgat aacatgtatg gtctttgtcg ttaatgtcat
    56941 aatagtatta ttatagcagt tgtttttaag atatgaaagc gttttaccta atcctataaa
    57001 gaaaaagcaa aggagctggc ctatgatagc caaccccttt agtgatggtt aggacatgac
    57061 ttggaaaagc aaaactgcta aagccgctcc aataattggt cctacaacag gtatccaagc
    57121 ataagaccaa tcagaatctc ccttgttgtt gagtggtaga atagcatgaa ctagacgagg
    57181 tcctaaatca cgcgctgggt taatggcgta acctgtcgtt cctcctaagg ataatccaat
    57241 cccaataacc aaggtaccta cacagagggt tcctagtcct gctggcatat catataagcc
    57301 aaatgccaaa ataccaagca tcaagacaaa ggtcccaaag atttcactca ataggtttga
    57361 gctagtatct cgaatagcag gacctgtcgc aaatgtccct aaaatatcag cctgactctc
    57421 agcagccaga taatgtggcc tgaactgaag gaataccaga gttgaaccaa ccatagctcc
    57481 caatagttgg gcaaggctat aggcaatggc tgttgaccaa gcaatggttc cactcatggc
    57541 aaaagcaagg ctaacagctg gattgaggtg ggcaggggca actttgccac tgataaagac
    57601 tgccacagca actgcaattc cccagccagt cgcaatcacg atccagccag aagcatgggt
    57661 tttcgttttg ggcaagacaa cccctgctac cacaccattt cctagtaaaa ccaataaggc
    57721 tgtacccaaa aattcaccaa agatatccat attaaccctc ctactggcct tttagggcac
    57781 tcaaatcatt gtctgcaatc acgcgacgaa gatcgtcttc ttgtgccact ctttcctgat
    57841 cagaccattc aaaatgttta gccatttctt taatcactgg gtcaatcaaa gcatctagac
    57901 tatctcgcat aaataagagg tgatttgttc ttctcaagaa ataatctgtc ggtttaagag
    57961 ccatttcata atccatcgca taatgtaagg acaaggtttc agctaaactt aacccttcag
    58021 ctgctgttaa ttgacgagtt aaggcaaaga cttttggcgc attagaacca taaaggtttg
    58081 ccaaatacct agcatcatcc atcgaaagac cactaagagt tcctaattga gcataggctt
    58141 ctatttctga atctacattg gctggattga tttcacctcc tgaaacagga taggtttttg
    58201 aattgataag cttgaaggat ttgccaaact cttctttgag ggtttgaata atccctgtca
    58261 atgctccttc agccattttg cgatagtcgg taatcttacc acctgccaag gtaaagaggc
    58321 cattctcatc acggtcaaaa cttgaacctc gtgacactgc agacggatcc aattcttttt
    58381 cagatgtgct ggtttcaacc tgcttaatag ctttttcaac agcttctcgg ctatcttcgt
    58441 ggttaatata ggctttgaca gtatcaacca agtgatcaaa actatcatca ctgactttac
    58501 cgctgttgcc accattgtag tcagaagcac tattacctga taacaagggg cgaaggccag
    58561 cccaactgct ttcaatatca tcaatggtca cgttggcatt tggaaagcgg ttattgacaa
    58621 cgcctaacaa ataatccaca tcttcttgag taacttgtgg gtgctccaag tctccagtgt
    58681 agtccgtgtc cgttgttcca aaataagttt tttcttcacg tggcaagaca aagaccatac
    58741 gaccatcatt taaccctgtg tcaacataga caggttgaga cactggtaat ttttgacggt
    58801 ccactaccag atgcacccct tttgtagggc gcatttgatg aatcggttgt cccttatgag
    58861 agaattgacg aatctcatca ctccatggac ctgtggtgtt gatgactaat ttagccttga
    58921 taataatttc ttgatctgac agcaaatcac gcgccttcac accaataatc ttaccattgt
    58981 catctagcaa gaaatcttct gctttcacat gactagcaat aagagcccca tcacgattag
    59041 ctcgtttgat attttcaata acaagccttg cgtcattatt gcggaaatca aggtaaaccc
    59101 caccaccaag caagccttct tgttttaagt ctggttctcg ttttaagact tcttctttag
    59161 ttaacacctt gttggccgct ggcgtattgg acacgcctgc taaaagatca tacaaatcca
    59221 tagcgacctt caaacggaac atgctaaagg tactgccagg ttcgtcataa acaggtaata
    59281 acatagggtc tggttttgga atgtggggtg caatttgttg caccacagcc cgctctgaca
    59341 ccgtatctga aaccacctcc acatcaaatt gtttcaagta acgaagcccc ccgtgaacca
    59401 atttggttga acggctagag gttccttgcg caaaatcttg catctcaatc agacccgtat
    59461 ctaggccact agctgccgcc tgaagtgcca caccagcacc cgtaatacct cccccaataa
    59521 ttagtaggtc taaatctctt tcttgcattt tttgaagagc taagcgtctt atctcttttg
    59581 aaaattccat tccatcctcc tctagttatt ttgtatcgtc atctgcatct tcttcttggg
    59641 tgaaaacttg agttgcttta acagcgcgct tccaaccctt gtataatttt tctttgcgcg
    59701 attcattcat gctagcctta aagagctggc ctgtggcatt taactctttc aaagcatcca
    59761 tgtcttccca gtagcccaca gcaagtcctg ctaagaaagc tgctcctaga gctgttgttt
    59821 ctaaattttt agcacgggca atatcaattc ctaaaatatc agcctgaaat tgcatgagca
    59881 tattattcat ggctgcaccg ccatccacac ggagctgttg aatgtcaata cctgaatcca
    59941 cctgcatggt attaataaca tctcgcactt gataggcgat agattgtaag gttgctttga
    60001 caaagtcttc tttgctggta ccacgtgtca agccaaagac agatccacgc gcattagaat
    60061 cccagtaagg agctcctaaa ccggtaaaag caggcacaac ataaacttca tcgtcactag
    60121 ttgatgctag agcgaactgt tcagattctg gtgaagtctc aatcatttta agaccatctc
    60181 gcaaccattg aatggcagag cctgcaataa agatggaacc ttccaaggca tagtgaacct
    60241 tcccattaat cccgtaacca atggtggtca aaagattatt actcgataac tgcatctcat
    60301 caccagtatt catgataatg aaagaacctg tgccataagt gtttttcacc ataccaggct
    60361 caaaagctag ttggccaaac aaagctgcct gttggtcacc cgccatacct gaaataggca
    60421 cttcgccccc ataaaaatga aaggcagctg ttttgccata aatttcagaa ttggatttaa
    60481 cctctggaag catatctttt ggaatattta aaagctctaa aatctcatca tcccatgtta
    60541 agtctttaat attatagagc atggtacgag ccgcattgga ataatccgtc acatgaacag
    60601 caccatctgt caatttccaa accagccaag tatcaatggt tccaaaaagt aactcgcctt
    60661 tttcagctcg ttcttgagca ccaggaacat ggtccaaaat ccaacggatc ttggttgcag
    60721 aaaagtaagc atcaataaca aggcctgtct tttcatggat catttttgta tggccatctt
    60781 gtttgagttg ctcagcaatt ggtgccgtct gtcgtgattg ccacacaata gcattataaa
    60841 taggtacacc cgtttttttg tcccaaacca ctgtggtctc acgttggttg gtaattccga
    60901 ttgcttcaat ttggcttggt ttgatgctgg actcaataaa agcacccgca ataacagact
    60961 gaaccgaatt ccaaatctga ttagcattgt gctctaccca accagcgtgt gggaaaatct
    61021 gagggaattc tttttggcta ctgctaacct tttccccttt ttgattgaaa ataatcgctc
    61081 gtgaacttgt tgttccctga tcaatagcca tgatatactt ttcttgcgac attcattacc
    61141 ctcctttaag taagcgtttt cctatttgat tctattatag ctaattttat cagaaatata
    61201 ttatcaagaa tttttaaagc taaaaaaaaa gctgataaga taggtagctt atcccactag
    61261 atgatcttga aaaatccact gatgacaacc acgtctcctc atttctaacg aggtaatctt
    61321 tcttatcaaa gaaaatcaaa agacccaaca atcactctgc taatccagag tcatcattgg
    61381 gtcataaaga gaactaagcc tcaaaggcaa cacggtatca aacagccgtg cctaagaggc
    61441 aaagacaatt ggacacaaga gttaaggctg tcttattcat tacagttctt gattagtcat
    61501 tgattggttc agaagatttt tccacaatat cccctgagtt ggcgtcaatg gtatagctgt
    61561 attcttgatc tttgttttga aactcgattt catacacggc tttgccatct tcattatctt
    61621 gtgtaactga tagcatttga gcatcagctt ccgtaacaga agcatctttt aacgcaattg
    61681 atttggcttt gtcttctgaa agtttaactt tcttgctagt ttgacttgtc tttggttgat
    61741 tatccatatg atcgtcttta tcatccatat cacaggctgc aagactgagt aaagagaggc
    61801 tggctatggc tagtagagag aattttttaa ttgtcataag tactaccttc tttctttgat
    61861 ttcttctatt ataactcaaa cacatggttt ttcccaatat tttgactata caatataaaa
    61921 acgtgtggtc acttcgaagt atcataccat ttaaaataaa agctaacagt catcacgata
    61981 aacaaaaagc agttcaaagc tgctttttgt cttatgattt tgggtcatct aatgaacggc
    62041 cgtgcaagcc tttttcacgt tgcacctgtc ttaatttttc aggggtcacg tcgtttcctt
    62101 cttcgtccac caatttgatg ccttcgatat ggtgtctgac agagcgacga tagccttcaa
    62161 tgtattcttc acggagtttt gcctgttcca ctttttcagg tccagtcaag cctaccgttt
    62221 ttttcttttt agccagctca ttgatacgag caattttttt aggatccatg ttaagccact
    62281 aagagcctgg gaaaaaagtg taagacttaa aaaactgact tgactctcac tgtgaaaagt
    62341 aatgtttaaa ggccttgttc tttccactcg ggtactgaac tcacttttct agctaagtcc
    62401 ccaacggctc tttcctttct atttacttgg tgtttagttg gttaaaagca gcaatggtct
    62461 tagctttgct tactaaatct gataaaatag ctacacggtt gttcttaagg gcttgatctt
    62521 ctgccataac cattgtatta tcaaagaaat cattaatcac tgggctaagg gcaaagacct
    62581 gttctaactg ctgggcagca ctgcctgcta gagtcaagcc ttgaatagct gcaaacaaag
    62641 tgttttcttg ctcattttca aagaggctag ggtccacctg aacagaagcg tccgcttttt
    62701 ctgccaaatt aaaagcacgt gacaaagatt caactgctgg tttgtaattt tccgtatggc
    62761 tggctttgac aagtgcttca gctgccgcta acatttcagg aaccacaaag gttgaactct
    62821 ctaaaactgc ttcacgaata tcttttggtg tggctttgcc catcatctta tccacacgag
    62881 cacggataaa gttcatcaca tccgccttat tggcataggt caaactatca aaggacaagt
    62941 catataagct atctaccagc ttatccattg ggatgcgcca tccaaaatga tcaagaatac
    63001 gaacgatacc ctgcgttgcc cgacgaagcg cataaggatc attagagcca gatggaatca
    63061 agccaacaga aaagaatgac aagagagtat ccaatttatc tgccaaggct aggacagcgc
    63121 caactttggt ttcaggtagc gcacctcctg cagcatcagg taagtagtgt tctcggatag
    63181 cccttgccac agcagcatct tcaccagcta gaagagcata tttttcaccc ataatccctt
    63241 gcagctcatc aaattcacca accatacctg ttaaaaggtc aaatttgtaa atttgggcag
    63301 cacggtcaac agctgtgact tcctcagcag ataggttggc ttccttagca agtgatgcgg
    63361 caatgacacg cgtacgatcc atgtgttcag caagagagcc gattttttca tggaaggtca
    63421 cattggtcaa tttggcaacc aaatcagcaa tttgcaattt ctgatcctca cgccagaaga
    63481 attcaccatc ttctaagcga gctaccaaaa ctttttcgtt ccctttaata acattttcaa
    63541 tggcttgatc attcccatta cgaactgata caaagtttgg catcaagtga ccagcctgat
    63601 cacgtactac aaaataacgt tggtggtttt tcattgatgt tatcaatact tcttctggga
    63661 catcaaggta tttagcctca aaacttccca tgaaagctgt tggaaactcg accaagttca
    63721 aaacttcatt aagcaagtct tcgtcaatgt caacttgcac accctgctcc acttccagcg
    63781 tcttgatttg ctccacaatc atctcttgac gctctttagc atcagcgata acaaactggc
    63841 tgcgcaaatc agcctcataa gaatcagcac ttgtgatagt ggtttcagta cctaaaaaac
    63901 ggtgaccacg gctgacgcgt ccagaatgaa tatccaagaa gtcaagttcc aaggcctcat
    63961 cattcaacag aactgtcaag gtgtgaacag gacgaatgta ttcaaaacta ttgttagccc
    64021 agtgcatgct gactgggaag gtcattgctg acaacacttc agtaacgcct agaagcactt
    64081 ccttagcagg ttttccagct tcgtgtttgg tcacataaac gtattcttct cctttgactt
    64141 cgcggaattc gatagcatct gtggtcaagc ctttgccacg aacaaatcct tgagcagctt
    64201 ttgagaaatt cccatcagca tcaagggcaa ttttcttagc aggcccttta aagtcctcag
    64261 tcaaatccgt ttgctgagca gctaacccag acacacgcac tgccaaacgg cgtggagttg
    64321 aaaaggtttg tatatcttca aaagagagat gattttctgt taagaaagtc gccaagcgct
    64381 ctcccagttg tttttcactt ggtgtgacca cgtaggctgg aagttcttcc agaccaagtt
    64441 cgattagtag atttttactc ataattaaga taccaagggc gttaagcgga caccatcaaa
    64501 atagcaaagc gacgcaggtg cttgcaccta ggaagtcttg gtctttttga catagtccgt
    64561 agcccgtgct cagttccttt ctctaaaaag tatctttttg attgttccct taggtagggg
    64621 gacgcaaggt gaaattatcc aatggataat ttcagaaaac aaaagtgttc cattcctagt
    64681 tagccagcct aaagtctcgc caactccctc gttcgataag taaccttgcc gaattgtcac
    64741 tacagcggga gtaaccttga ctcggcgacc ttcggtcgcc cacttcttgc tcgctcttaa
    64801 gattacaaag ctcgcaacta gatcatcttt aaatcgactt attcgccatc ttcagctagc
    64861 aagattgcgc gtgttgcttc atccaacagt ggaaatccaa gtttcttgcg ttctgcaaca
    64921 aaggtcttag caacgacacg tgccaaatta cggatacgag caatgtagcc tgcgcgttct
    64981 gtgacggaaa cagcgccacg ggcatccagc agattaaacg tatgagaaca tttgagcacg
    65041 taatcataag ctgggtgaac caaaccttct tctagggcac gcgaggcttc tttttcaaac
    65101 ttttcaaagt tttcaagcag catgtcttgg tctgacattt caaaggaata ttttgaatgc
    65161 tcatactcag gttgcaagaa gatttcacca tatttaacac ctggtgccca ctcaatatca
    65221 tagaccgaat ccacttcttg aatataggaa gctaagcgct caagaccata agttacttct
    65281 gctgtcactg gagatgtcgc aaggccacca acttgttgga aatacgtaaa ttgtgtgatt
    65341 tccattccat caagccaaac ttcccaacca agccctgctg atcctgttga ggggttttcc
    65401 cagttatctt caacaaaacg aatatcatgt tctaaaggat tgatgcccaa tttttccaaa
    65461 gaagcaaggt aaagttcttg aatatttgat ggtgatggtt tcatgaccac ttgaaattgg
    65521 tggtgttggt aaagacgatt tgggttttct ccgtaacggc catctgcagg acgacgtgat
    65581 ggctctacat aagccgcatt ccatggctca ggacctatag cacgtaagaa cgtgtaagga
    65641 ctcatggtcc cagctccttt ttcattgtca taggcctgca tgagcataca accctgatca
    65701 ttccaatatt gttgtaaggt caagatgatt tcttgaaagg taagtttttt agacatttcg
    65761 tactcctttg atagtagtaa aatggtatat cattgacaat cgttttttgt catcagtaaa
    65821 atacctgacg atgttactag catgtattac aggtctaggc accaaaaaac cgcattttga
    65881 tgctcctaaa tcataagacc taggggcgtc aaaacgcggt tccaccctaa tttattactt
    65941 cgtttatata gtatcttttt gggcaatatt gacaaatata cttaatcaca ctgcccaaac
    66001 ggaagcgcca atctgcagtc ctaccattcg gctctaacta ccccgaactc gctttagata
    66061 agatacttgc atcctttttc ctagagtcta gtttagcata aagccattag tttgtccatc
    66121 atgagcttaa ggttttgttc gagtaccgtt tggaataatc acttccgcta atagcttgtt
    66181 ttcttctcga atacgtaaat atattactac aatgtagcat gggaaaagaa gcatagccgt
    66241 aattttagca tggcaaagta aggctatgcc caccagctca ggggcgatat ttaaaaagta
    66301 gttaggatgt ttaatcgttt tgaacaacca gtgatccaca tatttgtggt cttttgctaa
    66361 catcaatttt acagtccaaa tgtcacctaa gatacgtgtc acttcatata aaacagctac
    66421 tgataataac atcaacaaaa gacctaaaaa actgatgcca tcaaacttaa tttgtttaag
    66481 cagcgcttca atcaccgcaa acacataaat cataatgtga agtaacgtca aaaatttcgt
    66541 gttctgagca ccaaattcct gtcctccttg ggctaatatg gctttttcat ttgttatcga
    66601 tttcttcaaa aatactaaac gaatagtaaa catggctaac atcactaaaa agatggtcac
    66661 aatacggctc cttattttca ataatagttt ctttcacaaa acactaataa agattatagc
    66721 taaatgataa acctttgtca aaccgttttc aaaaaagatt tagcgaatta tggctaaatc
    66781 tttgtagttt cttaaaaact tgtagtatca gggttaggaa tcgctgacat tcctgagaga
    66841 tagcgaattg tttttttatc ttctggtgtc aagctcacat caaaaatagc catattttcc
    66901 ttgatgcgct catcatgcac cgattttggc aagggaataa aaccttctgc cagcgaccaa
    66961 gctaaggcaa cttgtgccac tgttttgtca tatttattag ctaactgctg catagtctca
    67021 ttatcaaaaa tctccccttg tcctagagga ctccaagctt ccaataaaat ctcatttgcc
    67081 ttacaataat caaccacttc cttttgatag caacctgggg ctaatcgaat ctgattaatt
    67141 gctggagtta ttttagctgt ctcttgaaga gcttctagat gatacaccat aaaattgctg
    67201 acgccaatgc ttttaataag ccctgcttca accgcctctt ccatatattg ccatgcttgg
    67261 gcatttgcct ctttccaagt gttacgcaga gcttttgggt ttggccaatg gataagatag
    67321 agatccacat aagccagacc aagacggcca agagaagcag ctaaagcgtc ttttgcccct
    67381 tcataactat gggcgtcatt ccagagttta gttgtaataa ataagtcttc tcgtagaacc
    67441 ccagaatcct tgatggcacg acccacactt tcttcatttt tataaatagc tgcagtgtca
    67501 atatgacgat agccagcctt gatggctgct aaggtagatt ggtaagcttc ctcaccatcg
    67561 gctgcttggt aagttccaaa tcctaaaacg ggaatctcat agccacttgt catttttact
    67621 gttgttacca tcacaaaaac ctccttttat caatctctgt aagcgattac tgtaatctat
    67681 tctatcataa agaaagaaaa tacaaaaaga attggcctgc cagacatagc taccccaatc
    67741 cttttgtatc tcttaggcat caaaagcttt ttgcccattt aaataggttg caacaagtgt
    67801 taaatcctta tcaagaacaa taaagtcagc cgcatgccca gctttgattt gaccacatac
    67861 gtcgtcaata ccgacagaaa cagctggcac ataggttgcc atatgaatgg cttctgccgg
    67921 agttgcgatt ccccaggcca ctacatttct aaggccgtct tttaatttca aaatagatcc
    67981 tgccaagttt ccactctctt taagacgagc agtgccattt gccacaacca cagagaattc
    68041 ccccaagagg taatcaccat ctggtgaacc acctgctcgc atacagtccg taatcatggc
    68101 tacatgatca tgcccttttt gctgcatcaa aatatcacaa gcaattggtg agacatggtg
    68161 gccatcacaa atcaactctg cgtaagtatt tggaagatta taaaccgctc ccaccattcc
    68221 tggttcacgg tggatcaatc ctcgcatgcc attataagca tgaacccaaa cactagcacc
    68281 agcttgaaca gcttctttag cctcttgata agtaccgttt gaatgcccta aggccactgt
    68341 tacgccttgt tttgtcactg cggacacaaa ttctttgaca ccatcacgct caggagcaag
    68401 ggcaattttt ttgatgagcc ctttagcggc tttttgccaa gcatcaaatt cctccaagcg
    68461 tgggtttttc atataacttg ggttttgagc acccttatat tcttcggtaa aataaggacc
    68521 ttcaaagtaa atgccctgaa tcttagcccc tttaacttga tcagcgactg aagcaatagt
    68581 ccctgatact ttttctaact gctcaaaggt agaagttaag gtcgtcggta aaaaagacgt
    68641 tactcctgtt gctaatagtc cttcactcat ttgatgaatc ccttgggcag aattatccat
    68701 gacatcagct cccgcatagc catggatatg cgtatccaca agacctggtg caatttgata
    68761 accggtgtag tcaatgattt gcgcatctgc cggaacaatt tctgtccact ccccaaaaac
    68821 accatcatga agacttaggt agccagccgg tttcacctct gttgggtaat aaaaacaatc
    68881 tgctttaaga tagcatgtca tcttttttcc tccctttttt ccttattata cgccttattc
    68941 tttactttgt aaatggtata taccactttt tggattcaaa aaagaaaacg tggatgatca
    69001 ttcacgtttt ctcttttttt aaagctggtg tgaaagtact ttctctgcta aattcaaggc
    69061 atgatctgtg atgcgggtat agtgggaaat aatatcaata aaattaatac ctgcttgtgc
    69121 cgtacattct ccacaattca agcgcttaat gtgggtttta cgtaatcgtc gctctttttc
    69181 ttcaatttct ttatggcgag tcacaatagt ttgcgccaaa tctgtatcac tatcaacgat
    69241 agctctaatg gcatccagtg ttaaacaatg cgtcaattga tacatctctg tcaattcttg
    69301 acgagcagat attgaaaaac caatttgttt agatatgatg ccttcaatta gaatgcctaa
    69361 agactcagaa tgatctccaa ttctttccaa atcacgtgaa gagtcaagaa taccagccaa
    69421 gacttcattt tcacttgggc tgagggcttc gttagaaata tcaaccaaat aagtggttaa
    69481 ctcctcatcg atggtatcaa ctgctctttc ataacgcttg accttttccc caaatttatc
    69541 gtcagctgtc ataatataac tgtaagaagc ttcaaaagct tgaatcgcat aagaggctaa
    69601 atgaaccaat tccttgtggg catttcctag tgcgatagaa ggggcttggg taataagtaa
    69661 gcgatctaaa taaagggctt cgtatttgac cacttcatct tctcctggaa tgagtctagt
    69721 cacaatcata gctagtagac taatgaaagg aattaataag atggtattag tgatattaaa
    69781 agagccgtga gaaaaagcga tagtcatctc aggtgttaaa ctcaactttg attgtagcca
    69841 taacatcaat gatgtgaatg ggactaggat aatcataaaa ataattgtac cgatcaaatt
    69901 aaataacaca tgagctgctg ccacacgttt agcagcaata tttgaaccta tagctgctaa
    69961 gacagctgta atgcaggttc ctatatttga gcctaacaaa ataggaatag ccccctgtaa
    70021 ggtcaaaaga ccgcctgaaa acagaccctg taaaatcccg ataatggctg cagatgactg
    70081 aatcaacatg gtcaaagccg ttccgataaa gacaccttgg aagggtttat cacctaatgt
    70141 cgctaaataa ttttgaaagg ctgacacaga tttcaaagga tccatggcat ctcccattag
    70201 gttcagcgag aagaaaattc ctccgacacc aaaaatgata cgcccaaaat tgttgagctt
    70261 tttattagag gtaaagaaaa gacaggctgc accaataaaa atcatgggca aagcgtaatc
    70321 tcctagttta aaaccaatta aaaacgaagt gatagtcgtt ccaatattag cccccataac
    70381 aattccaatg gcttgtcgca aatttagcaa acccgcagaa accaaaccaa ccgtaatcac
    70441 agtgacgcct gaactggact gaattaaggc agacatggca attccgacta agataccaaa
    70501 aaagggatta ctggtgtatt tatcaatgta ataccttagt ttatctcctg ctgcttgttg
    70561 cagaccatct cccatatact tgatactgaa aagaaagaga cctaagcctc caaagaaatg
    70621 aaatgcaatg tcttgccaat ttactgacac aatattgtcc tcgctcaatt ttttagtcta
    70681 ttctatttta atgtattacg gtctttatca caaggttttt ttaagcgttt ctgtgtatac
    70741 cgatgtcaac atttgcatat tattggtttg ataaggtgtt aggcttttcc gatattttac
    70801 atcatttgtt tttgcacaaa tcttttcatt tcgtttaatt agaggtataa tatggctacg
    70861 atgaaacaat atcataaagg agattccatg actaaatcac aaaaagaggc gctttattgg
    70921 atgttgagtg ttctaactat cactctaata ggtggctcct gccttatttt tggatcccac
    70981 cctcaaacgc aagataaggt agctaaacat tctaaaagtg ctgctagttt actaaaaaaa
    71041 gcagttaaag cagttaatga cgctgatcgt ttagccactg cagctgctat ccaagaagcc
    71101 cagaaagctg ttgataaatt agcagaatct tctaagaaaa aaacgctaca agaacagcta
    71161 aacgttgcca aagcaaagca agagcaagaa gatgcagcta ctcaagcagt taaagctgct
    71221 gaggagactc tcaatcaaaa tcttaaagat atcgcccaaa aagcagttaa cgacttaagt
    71281 aacaaaggta aaaaagccgc tttacaatct cggttagacg ctattttact agcgaaaccc
    71341 attattgatg aatttccaag acaaagtgga gaaataacag ataactctta ctggacacct
    71401 ttcccaggag acgtctcaga tacttatgat aattcccagt cacctacttt agacccaagc
    71461 tcagaatctt cagcttcaga tgttacgcca caacctagtc atcctgatcc aattccacct
    71521 cagacctctt cagaaccttc cgactcagga gacaagcaat catcaaaaga gtaatacaaa
    71581 agtttttcgt aaaatcaatc aataaacgtt ttagacgact atcttagtga ttagtcttcc
    71641 tgacatctta aaaaagctag ctcaaatcaa aagagtctag ctttttgttt tgttagatag
    71701 cattaaattt cgtagcccat taaaagtcct ccgtcttcag cataaaagct acacaaacct
    71761 gaggtccttc cagtttgaat cacagcatca ggatataaag atttgatttt ttcactgatc
    71821 tgctcacaaa tttttggatt ttgagcatga gcaatgtaaa cttttccgcc tgcataaccc
    71881 tctttttgaa tttcttctat caaagcagaa actgcttttt tttgaccacg cgctttttga
    71941 agaagttcaa gcgttccttt attgctagct ttcccaacca ttctaatatt gagtaagcca
    72001 attactttac ctactaattt actcagtcga ccatttttaa ccaaattatc aaccttggca
    72061 agcacaaaaa tcaaacgtgt tttttgctga taagctgtga tctgtttgac aacttcttca
    72121 aaggataatc caagattgat caaccgctca agctccagta cgagcaaatc catctcgcca
    72181 cctgctgata aagaatcgat taggtgaata ttgacattag gattttcttc aagaagttca
    72241 tttttagcca gtcgtgcact attatgactg ccagataagg tccctgtaat tgtcataacg
    72301 ataacattat ctgcacctct ataggcctgc aaaaaggctt ctgggcttgg acagctagat
    72361 gtcgttgctt tagacgactg gtacatagtt gtcatcatat tatcgatatc taatccatca
    72421 tcatctctaa aaatttctgt gccaatctgt agggtcaaag gcacacgttc aaagcgcaac
    72481 tctttggatt gtctagtcaa acttctaaga tcacatcctg aatctgttac aattttccaa
    72541 gtcatttttt atccttcttt ttctctaatt tgtgttcggt aacaaagacc agattattaa
    72601 gccttcgcta agatgtctag gctaatggta ataactaatc attaaatcct atgttttatt
    72661 actagccttt tcaatagtta gtaaagtcat ccaatagagc tatacaagga ggtaatgagg
    72721 ctcctgataa ctaactttag ttgacaaact aagacttttc ccataaaatt atatcattat
    72781 taagtcggtt tttgctactg ataactcatc agatgtaaca cttgaaaggt atttgtgatg
    72841 actgataaag cactctcaaa aagatcactt caaaacttaa cacaatttaa taaagaaaca
    72901 cgacgcatag cacgtgaatc tatggaaatc gccttactaa atcttctaga aacaaaacct
    72961 ttaggtgata ttacgatttc agaattggtg acgaaagcag gagtatctcg taacgctttt
    73021 tatcgtaatt atacctctaa agaagccatt atagaacaac tgttagtagg ggttatccgt
    73081 cgtatttttc gtggactaaa acaatttgat attaaaactc aggcttatca agcctggctc
    73141 tatcttttta ctgaagctaa aaaagaagct cagcttctta aaatgatttt caaacatcac
    73201 ctgcaccatc ttctaacacg attagtcact aaacgtctga aagcttatca aaaattaaaa
    73261 gacaaaaaac aatcgcacta taagcgcctt ttttggagca atgctattgt ttctgtcttg
    73321 acaaactgga tttcagatga catgatcgtt cctgccgaag aaatggctgc tatgggcttg
    73381 cctctattaa cgtaaaaagg ttccttttgg gaaccttttt ttatataata gttagtcttt
    73441 ttgagctgca agtgcaaact gacggatagc ctgggccaca cccgccatat cattagtcaa
    73501 agtgactttg tcagctaatg gcttgatagc tgctgaagca ttttccatag caactcctaa
    73561 accagcataa gttaacatct caatgtcatt gggagcatcc ccaatagcca tcacttggtc
    73621 agcagttaaa cccaaatctt ctactaattc tttgagagcc gatgccttgc tgactccctg
    73681 agggagaatt tctaaaatat tatcttggct acgaacaaca tgaaaactct gactaagctg
    73741 atttctcacc gcacgttcaa aggcatctag cgcagctttt tctcctaagt acatggcttg
    73801 aaaaatcagg cgaggagtgt ccgacagctc tgctaaggag acaggcttga caatggtaaa
    73861 taccaaatct ccatcttcct gcacaaggtc tggcacttct tcttcaagca ccaaataatc
    73921 gttttcctca gttaaagtca ggtaaatatc tggaaaactt tggcttagct cttccagcaa
    73981 ttcaatatct gaaaccttca acatttttga atggcgtaat tgccagtcag gactactata
    74041 agtactacag ccattattga taatgaggaa ttcctcttgt gtcaaaccta attggtcaaa
    74101 atagggtctt gtccctgact gaggccggcc tgtgcataag acaattttta agcctgactg
    74161 agctgcttct tggatggctg tgatattctc ttttggaatc tgtttgtcct ggtttaataa
    74221 ggtgccgtcc aaatcaattg caattagttg aatcatccta tctttcctct ttccatttga
    74281 ttttagggag gttccatttt ttacggttgc caatcatgcg taaagtcgtg agtaaaacaa
    74341 ccaaggcata acattcaatc gttgaatctg ctagtttaaa atgcaaaaca atagctgcaa
    74401 gaatagacca cccagcatag atttcactac gcaaaacact aggttttcgc cctgccagaa
    74461 tatctctgac aacacctccg cctgcaccag tcaacacagc tgctacaatg acagcactta
    74521 aaggctggtt aagacggaca gcatgcaagg ctccttggac actaaaagct gccagaccaa
    74581 tggcatcagt caaaacagct gcccgtaccc aacctctagc tattagctta ggaaaaagca
    74641 taatcaaaac catagcaaag aaagcgcaag tgaattctgg cttttgcccc cataaggcct
    74701 ctataggtaa accaattagg gtgtttcgaa tggctccgcc tccaaaggct gtcacgaaac
    74761 ctaaaataaa aatccctaaa atatcaaatt cttcttccat ggcaacaata gcaccagaaa
    74821 gagcaaaggc aatggtcccg atgatattta aaatttccca catatcaatt gtcataagct
    74881 accctattgt cttttagtct tcttttagtt taccacgttt tcctttaaaa aataagtaga
    74941 aaaagataaa atgtaaggat aaaaaagcaa ggataaaacc cattttcatc cttgctacaa
    75001 aagattcaaa caattatccc catacttatc ttattacatc aatgagagct gcttgatagg
    75061 ataaggttgt tttagatttt ttccgtccaa gggctagcgg tctcttcgag taccctgttt
    75121 aactcgtcaa tattttggaa gccttcagtg catagccact ttcttgcttc gtcctctcct
    75181 ttagtaatat aaactggaac ggatcctgcc cacgtggcac gcccacacaa aacaccgcta
    75241 aattgagcac ctgctgctgc tgcaaagtat aatgtctctt gaaaaagttt ggcagatacg
    75301 cctgcactca aatagatata agggaggtgg ctggcagctt cttggtcttg aaaagcttta
    75361 atagcctcag cttgactgta atggacttcc ccttcagtaa aaccttctac ataagccata
    75421 ttaacaggaa cctctacttt tagcacatca acgccaaaac gcttatccga aaatactgac
    75481 atagcaccgt taaccttatg tggcttaagc tttgcatatg ccgcactgtt gttatctgat
    75541 attctctcat cataactcaa aagttcaaga aaaaaaggaa tgtcttcagc tgtacattct
    75601 gaaccaatgc gttcaatata agcttgtttt tgtaaattga tttgttcatc tccatcaaca
    75661 tcataataga gcaaaaattt aatagcatct gcacctgctg ctttcaaccg tttgaccgac
    75721 cattccacta agcaatcggg taaacgacta gtggttgtag catcataacc tgttttttcg
    75781 taagctaaca gtaagcctgt ctgattagct cttaccttag tagccagcaa cccatattct
    75841 ggatctaata aaatagatga agcataaggc gtcaattcct cagaaacgag aactttcaat
    75901 gtttctatct gtgtaactgt cgcttctcct tcttgatgtg ctgccatcat ttgcttcagt
    75961 gcacctcgtt gatcaaaagc taaagctgat atgattcctt gatggctcac tttttctaag
    76021 taatgtcttt tatttgctgt gattgtcatg tgatacctct cttacttgaa gttgctgata
    76081 taattgttta aaagttgcca tagtcatcaa atcttgataa tagtgagtag ctagtctctt
    76141 aggcagactg cctgagaagt taagacatca aacggcttag caatagtact catgtggctc
    76201 aaagagactt cggcttcgtc cacatcactg tagggaccag cttccaaaat ttttgtctgc
    76261 atgccttcat gtaaaacagc aatacaattt ctcgtttccc ctttgatttt gaaaaattgg
    76321 ttagaaatgc cctgttcttg taactgatga atgataaagt cacccagttt actaccacta
    76381 aatcctgttg caataactga ccagcttttg ttaacattct ggtcacattt agctccttat
    76441 caccagctgt ttttgccgtt ctgtcaacac gattaaccgt gtccatagcc agacaatcta
    76501 aaggatagga aatagcgaca gaaggattta aggtaactgt taaactcatc tcttcttcct
    76561 aatcgtgata ctcaccacgg tcccattttt ctaaaaattc tgtaaagaaa tcaggatctt
    76621 cttggttagc atgatgagtt tccaagtggg ctattttagc aattagcttc ttattctctt
    76681 cagtttcttt gtattctgcc ttgataaaag cgtctataat atcacacata agaagttcac
    76741 cagtgatttt accaccaaag ccaatcacat tggcattcaa ttcttccttg gcataaagcg
    76801 ctgttgtcat atctcgaaca agggcggagc gaatacctgg taccttgttc acggcattat
    76861 taatgccaac tccagttcca caaatacaaa cacccaagtc tgcttgacca ctaaccacag
    76921 cttcgccgac tttttttcca aaaatagggt aatgggttct tgtatggtca taagtgccac
    76981 agtcaataac gtcatagcct ttagatttca aaaaatcaga aacagccatt ttttcgttgg
    77041 tgacaatatg gtcacaacca atcgcaattt tcatcacttt atcctccttt aggccatttt
    77101 attgagcatg tcaacacgaa tttgatgacg accaccatcg tagggaccag tcacaaaacc
    77161 tttgacgata ttcttcgcta attctggacc tacaatctct gcccctattg tgatcatgcg
    77221 ggcattgttg tgaccacgcg tcatgtaagc agagcgttca tctgacactt cagcagcaac
    77281 cattcctttt aattttgtgg ctaccataaa gggacctgct ccgtaagcat ccaccataat
    77341 gcctaaacgc ccttctgctt cattaacggc tttagccacc gctaatgtgt tatcaataaa
    77401 atcactgtta atatcagtca cgtcaataat gtcatagcct tcttcttgaa gaaaactttt
    77461 gatcaattct tttaatgcat ttccgtgtgc atctgcacct aaaataatag ccatcgtttc
    77521 tccttttcta atccaaatcg cttgccaatc tacaaaaaga taacaggatt acctatcatt
    77581 aggtcaggat tattgccagt aatcttagcg tcttccatta tttctttcaa gacaaagcac
    77641 ttgtgggttc ccacagagcg ccttgcctta catgagaaat actcttttca cgttaggggg
    77701 taaggcagaa ataccttacg cagttatctg ctattctccc taatttttta gtcagtcacc
    77761 tgacctgatt ttatttcatt gttttcgcat actcagcgtt acgtgccttc atttggttag
    77821 cataccaagc aaagagacct aggtaaatgg ccacaaagat gattaacgtg atgattgagg
    77881 caatctgacc tgttgtcgct tgaccaatca catagccaaa gattttttcc attggtcctt
    77941 caagtgttga atgcgtaatc aaggaaccag cgcttgtacc tgctggaaaa gcccctactt
    78001 ttttagccaa ctctgtcgca aatggagcaa tcatagttcc tgacaagagg aataatggca
    78061 ataagaggga accaaaaata atcatgcgaa tcaaacgacc acgtgtgacc acaagaagag
    78121 ctggtgtcat ccccatagca ataattcccg ccagtggtaa aatcccattg ccaacttttg
    78181 ataggagaac ggattcaatc aacatgattg gggcaagaat attggcacag gcccagattt
    78241 cagcgcgacc agcaatgaag ggccagtcca aaccaatatt gaaacgacgt ccatgcattc
    78301 tagcattggc aaaattggta atcccttgtg acaaaggctc aacagctgcg ataaaccaag
    78361 aaccaatcaa agagaaaagt tccaaacagg cacccgcggt aaagcctaga ccaaaccaat
    78421 ttttaacaga ttcaacacta aaatgaggat ctcccataat cccaatcaca aaacctagag
    78481 ccattccgat aaagaactta gagccccaga agccaatttt tttgttcaat ttagcagcat
    78541 caaagtcata tttatctagc cccggaaaga ccttgtcaaa aatcttatct aagaccataa
    78601 tgattggatt catcatgtag ttcatgtgag ttgaagtcat tggtgattga gaccctgtcc
    78661 caagaaggtc atcaaaggtc ggtttcatca aatcagagtt aatgattttc aataccccaa
    78721 caagaataac tgccacagta gcaatcaaaa gagacacaag gactggcaaa tggttgtgat
    78781 cagcatacca cataatcaat agacctgtga tagacaaatg ccaaatatca aaaatatcga
    78841 catcaagggt gtccgttttt ttcatgacaa tcatgacaat attaaccacc agcatcacca
    78901 gcaagaaata aagggtataa ggggaacccc aggtaattgt tgcaagcggt gcccaaccga
    78961 catcaataat attcaaactg attcctgtat ttttgacaaa ggcctgcaaa gactctgaaa
    79021 aagcccccgt caaaatccca ataatggctc caatacctgt aagagcaata gctaacttaa
    79081 tcccgccttc cagtgccttt gtgaatttaa ccccgaaaat catggctaaa cctgtcatga
    79141 caatcagcat gaccacacct gatcccaact gaataggaaa tcccagaatc ttgttaataa
    79201 tgtctaaaaa aggttgcatc atcttgtctc cttatgtttt tattaactca ctgcaaatgg
    79261 ttttctttaa tcacgcgctc taattcagca aaaacaggct cactcatgat tgggatacga
    79321 tagagaatcg gtcctgcttc tactgtggga attggcatct caaatcccaa gtcagttttt
    79381 gcaatcggcg taaaaatatc ataacgagac accaattctt ctgtgatgtc tttgaccatc
    79441 accgcatcac aatgcacatc atagccacga tcactcatct gagtttcaat cgcatcttta
    79501 atttgatggc ttgagttaac ccctgcaccg caggctgcta gaattttaat catgctgaaa
    79561 cactcctttt tctattaaat agtttgaaat agcttgttta tcatctttta gactggctag
    79621 acagctaaga ttgcctttcg taataaagaa ggtaataaga ttagatagaa tcgtcgtttg
    79681 accctcgttt tgactattga taataaagaa gaaatccgtt accaaacagt cttcctctgg
    79741 attaatcatg tgcttaaagg taagggcttg actatttcta acatagacca cttgatcaac
    79801 caagcaatac ttggtttctg tatgcggaat agccgcatac aaaatatctg acccatcttt
    79861 gaggtccact ttgagtcctg tcggaaatac cgcctcacgt tccactaaag cctgatggta
    79921 ctcttgcgtc acatacccaa ccttttccaa gtggctagca acaagatcaa aaagctctgg
    79981 ctgcgtcctt gcttcagtaa atagaatatt aggaaacact ccctaccgcc tttctataag
    80041 tatcaatttt taacaactgt catctcatca tcaacaaatt ggtaaccgtt tacaaaatca
    80101 ttatagtata accttcaaca taattcaaca tttttacgca atattttttg ttctatatgt
    80161 ttgtttttgt tttgtttatt ttgttttatt gaaatatgaa ggtctatatg ctatgataaa
    80221 cataagtaaa taaactatag aaaggagccc cttagatgtt aaaaagagaa agacttctaa
    80281 aaattaccga aatagtcaat gagcaaggta ttgttactgt gaatgatatt attcagactt
    80341 taaacgtttc tgatatgaca gttcgtagag acttagatga actggaaaaa gccggcaaat
    80401 tgatccgcat ccatggaggt gcacaaagta ttaccatgcc taataaaaaa gagcggtcaa
    80461 atattgaaaa acaaaccgtt caaacaaagg aaaaatggga actagcttca tatgcgacac
    80521 aactagtcaa tgatggtgaa acaatcttta ttggtccagg aacaacttta gaatgtttcg
    80581 ctgagcaatt aaaaaatcgt cagattcgca ttgtgaccaa tagcctccct gtctttaaca
    80641 tccttcagga cagcgaaacc attgacctga ttcttatcgg tggtgaatac cgatctatta
    80701 caggagcttt tgtagggtcc cttgctagtc aaaatatctc atccttaaaa tttgccaagg
    80761 cttttattag ctgtaatggc atttataaaa acgatattgc aacttatagc gaaactgaag
    80821 gagagattca aaagctagct tttaataatt ctattgaaaa atacctcttg gtagataacc
    80881 aaaaattcaa tgcctacgac ttcttcattt tttaccattt aaacaacatt gatgctgttg
    80941 ttacagattc gcaaataact gaggacgtca tcgaacgtta tagtcagttc acacaattat
    81001 tagtagccca cgaaaacaag gagtaaccgt ttcatcaaga atggacagcc tgtcagcgca
    81061 tcgtccttaa acaccttctg gcaaaagtga tttgccccca gagaggtgtt tttgttttgc
    81121 tcggaacaca cctgctaacg tcagagtctt tatgagtgac cacaaaaaaa gaagcccaga
    81181 ttaaaaaact ggaacctctt ttgagatgaa gtaaggctac caaaataacc taagaccatt
    81241 tatgtaattc aaatttggta tccttcaaag cacgcttgag taggaaagtt aaaggacgtc
    81301 ctgtcacctt agcctctcct ttttccaaat ttacctggac cgattgcaca ccggggacag
    81361 ctgataattt ttcagtaacc gttcttgcac aaccgtcaca cgtcattcct gtaacctgat
    81421 agtgtttttc catttcgttt tctccttcaa atggtttttc cttttaatcg cagggcattc
    81481 aaaacaactg atactgaact aaaactcatg gcaaaacctg ctaacatcgg gttcaatagt
    81541 ggacctccaa aaagatgaag taagcccatg gccactggaa tcatgaggac attgtatatg
    81601 aatgcccaaa ataaattttc cttgacaatc ctcatagtcg ctcgactcaa tgacatagct
    81661 ttcaccaaat ccagcatatc aggtttcatc agaatcacat ccgccgattc aatggcaata
    81721 tctgtccctg accccatagc tatcccaatg tctgctacag ccaatgccgg agcatcatta
    81781 ataccatcac ctaccattgc aacttttctc ccttgagatt ggaggtttgt tatcacgcct
    81841 gctttttgat caggtaagac ttgactgatc acatctgtaa tccccacttg agaggcaata
    81901 gccttagcgg tagcatcgtg gtcacctgtt agcatgatgg tgtgaattcc cagttgctgc
    81961 aaagcttcga cggtagcttg actatcttct ttgacagcgt cagcaatact gaaaagagct
    82021 cttagctgcc cctctttagc ataatataca agggtttgac ctttccctga agccttagca
    82081 caaactgact gaacagaagc taaatcaata ccaagggttg ccattaaagt agcatttcca
    82141 atcgccaaac gacgcccttc aagctgacca gtgactccta ggccggttaa agactcaaac
    82201 tcttccactg gtagactatc gtaaccagct tcctgagcag cacggacaat agcctcccct
    82261 aaggggtgtt gagaataggc ctccaaggaa gcagcttctt gcaagataag gtgatcatct
    82321 cccgaaaaag ttaggaggtt ttgaagactt ggtttcccct ccgtaatcgt ccccgtttta
    82381 tcaaaaacaa ccgtatctac ctgatgggct tgttctaaga tgtcaccacc tttaaaaaga
    82441 ataccatttt cagctgcacg ccctgttcca accataatcg ctgtcggggt tgctaaacca
    82501 agcgcacaag gacaagcaat gactagaaca gcgatggctg ttgtcaaact aaaacgaaga
    82561 ctttcctgta tgaataccaa ccaaaacacc cctgttaaca gagctaatac caaaaccacc
    82621 ggaacaaaga cacctgagac tctatcagca atggctgcaa taggtgcttt attttcttga
    82681 gcattctcaa ctagttggat aatttgtgct aacaaggtat cattcccaag cttatctggt
    82741 ttaatcgtga gggcgccttg accattcaag ctgcccgcaa agacattatc tttttctccc
    82801 ttttcaacag gcaaactttc cccagttaaa aaggattcat ccaaactgct atgtccttcc
    82861 acgataatgc cgtcaataga aactttttca cctggttgaa ccaggacaag gtcatcatag
    82921 ctaatctctt ctaacggcaa caattgccat tggctgtttc tccataccct cacatcagta
    82981 gccttcaagg ataggagctt ttgaatagct tgataagtac ggcccttaga acgactttca
    83041 aaatactttc ctagaccaat gagtgtcaaa atcactacca ccgattcaaa ataaagggag
    83101 tgcacaaagt gcgcccggcc cagactgatt tcaaccactc cataaagact ataagcaaaa
    83161 gcaaagctgg ttgctaaagc taccaaggag tccatattag gatgtccctt gaacaaagct
    83221 ttgaacccat tatggtaata atgacgattt aatactaaga ctggaatcgt caagagtagc
    83281 tgactaaagc tgtaaacgaa aggatagcga tctggttgca gaaatgaagg aagccataag
    83341 cccaccatgt gacccatagc taggtataat ataggaatgg tgaatagggc agaccacaag
    83401 acctgagacc aaataacctt taggtcttcg tcacgacgac ctgtttgcat gtgttttgca
    83461 tgttcatcaa agacttgtgc accataacca gcagctttta ccgcttgaat aactttggcc
    83521 gtttctaaat cgtcatcttg ataagtaacc gtgagtttct cggtcgctaa attcacaaca
    83581 gcctgttcta cttcaggcaa ttgattgacc gttttttcaa ttgttagagc acaagaggca
    83641 caactcattc cctccactaa aaatatctct ttagccatta atacgtctcc tttttctgac
    83701 agtggcactg cccaggcagg caattacacg gcacctcaag aactgcattt tcttttttga
    83761 cttctagtag ctcttggaat gcctcaattt cctctaaggt catcggtaag tcataaagcc
    83821 gttcaagaag tagacgcgtg tgttgccgct gacaaatacc gtctaaaaca gtcgctagtg
    83881 cttctttttg tagcaaagtc tcatccaaaa gagcttgata aatataggcc ctaccttccc
    83941 gataagatgt taaaagattt tttttaacta gcctaccaat gagggtctta atagtggaat
    84001 ctgaccattg atattttttc cttaaaatag taataatatc gctactttta atatcaccac
    84061 tggcccacac cacacgcatg acttcccatt cggcagctga tatctgttgc ataacgtcac
    84121 cttcattcac aatatattta cgtttgtaaa ttaattataa cgaatttaac tacatttgta
    84181 aataaataac ttttctcatt tttctatcct tatattgaca a
//
LOCUS       DAUCXI010000002        77641 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.002, whole genome shotgun sequence.
ACCESSION   DAUCXI010000002 DAUCXI010000000
VERSION     DAUCXI010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 77641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77641
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.002"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            539..1066
                     /locus_tag="VGY43_000082"
     CDS             539..1066
                     /locus_tag="VGY43_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEQ4301309.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            1066..2184
                     /gene="yqeH"
                     /locus_tag="VGY43_000083"
     CDS             1066..2184
                     /gene="yqeH"
                     /locus_tag="VGY43_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEQ4301310.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETEELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIGRINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFPGTTLDKIEIPLDDGTFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLARFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPDKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            2209..2517
                     /gene="yhbY"
                     /locus_tag="VGY43_000084"
     CDS             2209..2517
                     /gene="yhbY"
                     /locus_tag="VGY43_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEQ4301311.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            2586..3218
                     /locus_tag="VGY43_000085"
     CDS             2586..3218
                     /locus_tag="VGY43_000085"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEQ4301312.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLRMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDYYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKRVLDYITQEGLYQ"
     gene            3215..3808
                     /gene="yqeK"
                     /locus_tag="VGY43_000086"
     CDS             3215..3808
                     /gene="yqeK"
                     /locus_tag="VGY43_000086"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEQ4301313.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNPDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIEIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            3832..4185
                     /gene="rsfS"
                     /locus_tag="VGY43_000087"
     CDS             3832..4185
                     /gene="rsfS"
                     /locus_tag="VGY43_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEQ4301314.1"
                     /translation="MKKEELLKIVVEATDEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWHEAPAVALDAYLA"
     gene            4233..4976
                     /locus_tag="VGY43_000088"
     CDS             4233..4976
                     /locus_tag="VGY43_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ4301315.1"
                     /translation="MEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKSRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQDMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEVPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTETSKRWFFVAYK"
     gene            5197..6303
                     /locus_tag="VGY43_000089"
     CDS             5197..6303
                     /locus_tag="VGY43_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEQ4301316.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPAL
                     IDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTEDVID
                     YQKLIKVYEKKSEQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYA
                     KASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINN
                     PHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRY
                     TKARVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDE
                     MTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN"
     gene            6786..7502
                     /locus_tag="VGY43_000090"
     CDS             6786..7502
                     /locus_tag="VGY43_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ4301317.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            7705..8547
                     /locus_tag="VGY43_000091"
     CDS             7705..8547
                     /locus_tag="VGY43_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ4301318.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKTAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYKVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            8874..9719
                     /locus_tag="VGY43_000092"
     CDS             8874..9719
                     /locus_tag="VGY43_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ4301319.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGAQIAVPNDATNESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            9969..11033
                     /locus_tag="VGY43_000093"
     CDS             9969..11033
                     /locus_tag="VGY43_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301320.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFEQGKVQLSANALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            11034..11726
                     /locus_tag="VGY43_000094"
     CDS             11034..11726
                     /locus_tag="VGY43_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4301321.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSIFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(11780..13150)
                     /gene="brnQ"
                     /locus_tag="VGY43_000095"
     CDS             complement(11780..13150)
                     /gene="brnQ"
                     /locus_tag="VGY43_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEQ4301322.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VITSFVHPAGNYGDAFNAGVGVNNAFKDFPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEVTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFSDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQSFLAVVIFLACLTTSTGLITSSAEYFHKLVPTLSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTGLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLIL
                     SKTKKS"
     gene            13384..14598
                     /gene="sstT"
                     /locus_tag="VGY43_000096"
     CDS             13384..14598
                     /gene="sstT"
                     /locus_tag="VGY43_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEQ4301323.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGRQTNMTLIIVLYLFGTFASALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(14653..15327)
                     /locus_tag="VGY43_000097"
     CDS             complement(14653..15327)
                     /locus_tag="VGY43_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEQ4301324.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGVEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(15337..16728)
                     /locus_tag="VGY43_000098"
     CDS             complement(15337..16728)
                     /locus_tag="VGY43_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEQ4301325.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFGLEAFAAIVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFERPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(16798..17511)
                     /gene="rsmG"
                     /locus_tag="VGY43_000099"
     CDS             complement(16798..17511)
                     /gene="rsmG"
                     /locus_tag="VGY43_000099"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEQ4301326.1"
                     /translation="MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAI
                     TEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVITARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            17661..18218
                     /locus_tag="VGY43_000100"
     CDS             17661..18218
                     /locus_tag="VGY43_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEQ4301327.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            18265..19161
                     /gene="htpX"
                     /locus_tag="VGY43_000101"
     CDS             18265..19161
                     /gene="htpX"
                     /locus_tag="VGY43_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEQ4301328.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            19395..19928
                     /locus_tag="VGY43_000102"
     CDS             19395..19928
                     /locus_tag="VGY43_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEQ4301329.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VRYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            20195..20881
                     /gene="covR"
                     /locus_tag="VGY43_000103"
                     /gene_synonym="csrR"
     CDS             20195..20881
                     /gene="covR"
                     /locus_tag="VGY43_000103"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEQ4301330.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            20887..22389
                     /gene="covS"
                     /locus_tag="VGY43_000104"
                     /gene_synonym="csrS"
     CDS             20887..22389
                     /gene="covS"
                     /locus_tag="VGY43_000104"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HEQ4301331.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHEVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETHTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMIRV
                     QGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSKES"
     gene            22604..23098
                     /gene="nrdR"
                     /locus_tag="VGY43_000105"
     CDS             22604..23098
                     /gene="nrdR"
                     /locus_tag="VGY43_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEQ4301332.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            23082..24257
                     /locus_tag="VGY43_000106"
     CDS             23082..24257
                     /locus_tag="VGY43_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEQ4301333.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQENLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSCRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            24258..25160
                     /gene="dnaI"
                     /locus_tag="VGY43_000107"
     CDS             24258..25160
                     /gene="dnaI"
                     /locus_tag="VGY43_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEQ4301334.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLSDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            25223..26533
                     /gene="der"
                     /locus_tag="VGY43_000108"
     CDS             25223..26533
                     /gene="der"
                     /locus_tag="VGY43_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEQ4301335.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            26740..29838
                     /locus_tag="VGY43_000109"
     CDS             26740..29838
                     /locus_tag="VGY43_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ4301336.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLASNTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIEADLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMKDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNESRASMSIEEIKEILGLN
                     TH"
     gene            30081..30683
                     /locus_tag="VGY43_000110"
     CDS             30081..30683
                     /locus_tag="VGY43_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301337.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQAPSSKRFCSNDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            30723..32051
                     /locus_tag="VGY43_000111"
     CDS             30723..32051
                     /locus_tag="VGY43_000111"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEQ4301338.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            32097..32579
                     /locus_tag="VGY43_000112"
     CDS             32097..32579
                     /locus_tag="VGY43_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ4301339.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTF
                     LVALIDQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            32691..34265
                     /gene="mltG"
                     /locus_tag="VGY43_000113"
     CDS             32691..34265
                     /gene="mltG"
                     /locus_tag="VGY43_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEQ4301340.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAAKRTAQLYAEYKRQDAFQKESIAHNNKTAKHFQAIKGAVMTSEALKPTLLSE
                     KENSSLKTTNKRVVQANELQETASKESQVPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKTKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            34338..34820
                     /gene="greA"
                     /locus_tag="VGY43_000114"
     CDS             34338..34820
                     /gene="greA"
                     /locus_tag="VGY43_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEQ4301341.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(35440..36363)
                     /gene="yidC"
                     /locus_tag="VGY43_000115"
     CDS             complement(35440..36363)
                     /gene="yidC"
                     /locus_tag="VGY43_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ4301342.1"
                     /translation="MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEP
                     INKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITAYLLKPRLHKQIKEEYAKNPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(36445..36723)
                     /locus_tag="VGY43_000116"
     CDS             complement(36445..36723)
                     /locus_tag="VGY43_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEQ4301343.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATHTLALDIGDIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGK"
     gene            36984..37721
                     /locus_tag="VGY43_000117"
     CDS             36984..37721
                     /locus_tag="VGY43_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEQ4301344.1"
                     /translation="MVITSKTNQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYKTPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            37760..38260
                     /locus_tag="VGY43_000118"
     CDS             37760..38260
                     /locus_tag="VGY43_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ4301345.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            38275..38964
                     /locus_tag="VGY43_000119"
     CDS             38275..38964
                     /locus_tag="VGY43_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEQ4301346.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            39142..39384
                     /locus_tag="VGY43_000120"
     CDS             39142..39384
                     /locus_tag="VGY43_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEQ4301347.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            39562..40356
                     /gene="racE"
                     /locus_tag="VGY43_000121"
     CDS             39562..40356
                     /gene="racE"
                     /locus_tag="VGY43_000121"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEQ4301348.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVEHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            40353..41339
                     /locus_tag="VGY43_000122"
     CDS             40353..41339
                     /locus_tag="VGY43_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEQ4301349.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDG
                     IAATLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQRKVKVTPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQRFGDTVLIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNTKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKG
                     ENGFGYDPVFIVGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            41318..41839
                     /locus_tag="VGY43_000123"
     CDS             41318..41839
                     /locus_tag="VGY43_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEQ4301350.1"
                     /translation="MASETIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTQLGTVTIAQTHGHLYHINFTWDKLDYFAQEVA
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            41836..42297
                     /locus_tag="VGY43_000124"
     CDS             41836..42297
                     /locus_tag="VGY43_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ4301351.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            42294..43040
                     /gene="xerD"
                     /locus_tag="VGY43_000125"
     CDS             42294..43040
                     /gene="xerD"
                     /locus_tag="VGY43_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEQ4301352.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPVTLEKYYKS"
     gene            43040..43744
                     /locus_tag="VGY43_000126"
     CDS             43040..43744
                     /locus_tag="VGY43_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEQ4301353.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEEDLEQDLLEKIEEYSRFKAVS
                     QALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKTNHTV
                     IEPDDYKIEDMMASIKQRLEKENVISLSAIFEECQTLNEVISIFLASLELIKLHVVFV
                     EQLSNFGAIILRKEKK"
     gene            43741..44292
                     /locus_tag="VGY43_000127"
     CDS             43741..44292
                     /locus_tag="VGY43_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEQ4301354.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            44413..45135
                     /locus_tag="VGY43_000128"
     CDS             44413..45135
                     /locus_tag="VGY43_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ4301355.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLGLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKNRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            45132..45395
                     /gene="yidD"
                     /locus_tag="VGY43_000129"
     CDS             45132..45395
                     /gene="yidD"
                     /locus_tag="VGY43_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEQ4301356.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            45573..46121
                     /locus_tag="VGY43_000130"
     CDS             45573..46121
                     /locus_tag="VGY43_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEQ4301357.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNVARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      46230..46353
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            46432..46995
                     /locus_tag="VGY43_000131"
     CDS             46432..46995
                     /locus_tag="VGY43_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ4301358.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFALVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            46997..47650
                     /locus_tag="VGY43_000132"
     CDS             46997..47650
                     /locus_tag="VGY43_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ4301359.1"
                     /translation="MMTNKQTHFLIASFALLIFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQVLLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILVIGLSRIYLGVHYPSDILAGFVLGFGILQFIYPFYKQKRFEWRFLLKQD"
     gene            47943..48863
                     /locus_tag="VGY43_000133"
     CDS             47943..48863
                     /locus_tag="VGY43_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEQ4301360.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            48902..49483
                     /locus_tag="VGY43_000134"
     CDS             48902..49483
                     /locus_tag="VGY43_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ4301361.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVSAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADVYPLSLCQVY"
     gene            49589..50923
                     /locus_tag="VGY43_000135"
     CDS             49589..50923
                     /locus_tag="VGY43_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEQ4301362.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            51001..51792
                     /gene="pflA"
                     /locus_tag="VGY43_000136"
     CDS             51001..51792
                     /gene="pflA"
                     /locus_tag="VGY43_000136"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEQ4301363.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQINFITALFIEA
                     KKLGIHTTLDTCGFAYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            51923..52858
                     /locus_tag="VGY43_000137"
     CDS             51923..52858
                     /locus_tag="VGY43_000137"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEQ4301364.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            52934..53587
                     /locus_tag="VGY43_000138"
     CDS             52934..53587
                     /locus_tag="VGY43_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEQ4301365.1"
                     /translation="MITIFHSDKLTRQPFFQDLINYLDQHDYVILREIKKAFPNVTGI
                     DKAIESYVQAGYIRRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNHVVIKEKTNITRDDLTLANYFYRLKRGEKPSAEQMDLYDLLGDVNQEYALK
                     YMTTFLLKFTRKDLVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(53632..54669)
                     /locus_tag="VGY43_000139"
     CDS             complement(53632..54669)
                     /locus_tag="VGY43_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ4301366.1"
                     /translation="MLFMVNKKRRPLLKSHRHLLRLYTSLILLLVSLMGLALSLGESH
                     LSFLDLVHVFLGKSSHAISFIVINIRLPRILAAFLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQID
                     PTRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLIGA
                     PYFLYLMAKTK"
     gene            complement(54630..55682)
                     /locus_tag="VGY43_000140"
     CDS             complement(54630..55682)
                     /locus_tag="VGY43_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ4301367.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLVFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAEPGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKGYHQLRLVLAGAMVSILLSALGQGITNYYHLTNAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(55672..56604)
                     /locus_tag="VGY43_000141"
     CDS             complement(55672..56604)
                     /locus_tag="VGY43_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEQ4301368.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAITTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEGKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEVIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIVDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(56630..57412)
                     /locus_tag="VGY43_000142"
     CDS             complement(56630..57412)
                     /locus_tag="VGY43_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301369.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(57658..59103)
                     /locus_tag="VGY43_000143"
     CDS             complement(57658..59103)
                     /locus_tag="VGY43_000143"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEQ4301370.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGLSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMA
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL"
     gene            59191..60825
                     /locus_tag="VGY43_000144"
     CDS             59191..60825
                     /locus_tag="VGY43_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEQ4301371.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSVIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAISQIAEQLIRVIWMLLTTFFIMKLGSKDYLSAVTQSTLAAFVGMIASMAVLGY
                     YLWKLGLLKAICRKPNHHIDSDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEDRAIHLFVAVLFQTLLLALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            60992..61621
                     /gene="upp"
                     /locus_tag="VGY43_000145"
     CDS             60992..61621
                     /gene="upp"
                     /locus_tag="VGY43_000145"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEQ4301372.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            61845..62435
                     /locus_tag="VGY43_000146"
     CDS             61845..62435
                     /locus_tag="VGY43_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEQ4301373.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK"
     gene            62930..63223
                     /locus_tag="VGY43_000147"
     CDS             62930..63223
                     /locus_tag="VGY43_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEQ4301374.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKGYQPPSY"
     gene            63454..64089
                     /locus_tag="VGY43_000148"
     CDS             63454..64089
                     /locus_tag="VGY43_000148"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEQ4301375.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVTQEILTTREPGG
                     VAISEYIRELILDINHTTMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            64107..64982
                     /locus_tag="VGY43_000149"
     CDS             64107..64982
                     /locus_tag="VGY43_000149"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEQ4301376.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     GKRQVFIIKDCEKMHVNAANSLLKYIEEPQGEAYMFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLFQLAQERGLLRSQADLVAKLAKNVDQLEDLAQNSHFLEVMAQTERFVSIWL
                     KDQLQAYLALNHLVLLATEKEEQELILTLLTLLLAREQSQTPFKQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            65001..65240
                     /locus_tag="VGY43_000150"
     CDS             65001..65240
                     /locus_tag="VGY43_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tpl protein"
                     /protein_id="HEQ4301377.1"
                     /translation="MGKRSLSKDLPVATKVAAHRGKKAFEENTALATDLMKEVSRLMI
                     QNQLEMTFINSVFPLDQHVVLIPFSAEEHMDFYNC"
     gene            65645..65968
                     /gene="yabA"
                     /locus_tag="VGY43_000151"
     CDS             65645..65968
                     /gene="yabA"
                     /locus_tag="VGY43_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEQ4301378.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            65973..66836
                     /gene="rsmI"
                     /locus_tag="VGY43_000152"
     CDS             65973..66836
                     /gene="rsmI"
                     /locus_tag="VGY43_000152"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEQ4301379.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYTETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSISEILSYL
                     EETPLKGECLLIVAGAQVDSEIELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            66863..67255
                     /locus_tag="VGY43_000153"
     CDS             66863..67255
                     /locus_tag="VGY43_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301380.1"
                     /translation="MTEDQATILILGVYGIILAVFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(67302..67931)
                     /locus_tag="VGY43_000154"
     CDS             complement(67302..67931)
                     /locus_tag="VGY43_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEQ4301381.1"
                     /translation="MIKEFCAENLTLLPTLDAGQVSRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKKISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTTENH
                     LDTDAIEQLLPATQGLPLVFHMAFDHIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIEIMIGGGVTAENCQNLSQLTGTAIVHGTKII"
     gene            68230..68586
                     /locus_tag="VGY43_000155"
     CDS             68230..68586
                     /locus_tag="VGY43_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEQ4301382.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEVIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGR
                     VLQVGYRKPYQELDLG"
     gene            complement(68660..69487)
                     /gene="xth"
                     /locus_tag="VGY43_000156"
     CDS             complement(68660..69487)
                     /gene="xth"
                     /locus_tag="VGY43_000156"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEQ4301383.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIEALLSYFPNYLHVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDAQK
                     PVLATGDYNVAHKEIDLANPSSNRRSPGFTDEERQGFTNLLARGFTDTFRHLHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYWLASNRLVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            69721..70902
                     /gene="lctO"
                     /locus_tag="VGY43_000157"
     CDS             69721..70902
                     /gene="lctO"
                     /locus_tag="VGY43_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEQ4301384.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDHLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYYSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVDQKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSTGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            71166..76109
                     /gene="scpC"
                     /locus_tag="VGY43_000158"
     CDS             71166..76109
                     /gene="scpC"
                     /locus_tag="VGY43_000158"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HEQ4301385.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLMMTTTVAADELTTTSEPT
                     ITNHAQQQAQHLTNTELSSAESKPQDTSQITPKTNREKEQSQDLVSEPTTTELADTDS
                     APMANTGSDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS
                     MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFD
                     EDWENFEFDAEAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDDTKY
                     ESHGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIED
                     AVALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDP
                     LATNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVD
                     FKNIKDSLGYDKSHQFAYVKESTDAGYNAQDVKGKIALIERDPNKTYDEMIALAKKHG
                     ALGVLIFNNKPGQSNRSMRLTSNGMGIPSAFISHEFGKAMSQLNTNGTGSLVFDSVVS
                     KAPSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIA
                     GASLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNI
                     DGAVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQ
                     KGRFTLTSRSLKTYQGGEVTVPANGKVTVTVTMDVSQFTKELTKQMPNGYYLEGFVRF
                     RDSQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGK
                     HFTGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNN
                     QDFAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTL
                     LGTAFSGKSLTGAELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLPQATFDP
                     ETNRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQA
                     DGSFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKE
                     TLKDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKG
                     LKNNVYNDLTVNVYAKDDHQKQTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQ
                     YVVTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVRE
                     EVFYLAKKNGRKFDVTEGKDGITVSDNKMYIPKNPDGSYTISKRDGVTLSDYYYLVED
                     RAGNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYY
                     NNSGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKMTMLATSQ
                     ITAHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRI
                     EGNTKVNTLPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTAFATPTKTTTSAT
                     AKALPSAGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            76880..77587
                     /locus_tag="VGY43_000159"
     CDS             76880..77587
                     /locus_tag="VGY43_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEQ4301386.1"
                     /translation="MSKKKRKHYQVYEGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWATKKGLHWYLLSSVML
                     TGLAFGTALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
BASE COUNT        24997 a        13638 c        15929 g        23077 t
ORIGIN      
        1 gtaatcattt tttgatttac agttattatc atgtgttatc tggcgactgt cctgtttaca
       61 agtaagttca caagtatggg ataaaatagt ataaactata gtaaatactg aatagtcata
      121 gaaaaatatc ggcataggtc agaagagctg atatgtttaa cactttttgc ggatatctac
      181 tgtatttaaa tgtatttgat atccttgtca aggatatacg tctaaacaag ttcaaaacga
      241 aatcatttgt gattatctta tcaggagttg actcttgata agatttttgt atatcagtcc
      301 tgtggtacgt ttagatagct tggcagtgaa tttatagagt gtcaaacaac gagtgttttg
      361 tgttacacta accattagaa gagtctattt ttgagcatat caaggtgtta tcttttcgag
      421 ttgaggtatc atatctagtt gtaatgtcaa acatatctag tatatttaac tatggtttta
      481 aatgctattt caaaaaaaat atgataaaat agaaagtact aattattttg gagatgacat
      541 gagtatcgat gattataggc cgacctatat ggtagaggct atttatgatt taagagcaaa
      601 tgatttgttg cgtcatggta ttacggctgt tttagtggat ttagataata ccttaattgc
      661 atggaataat cctgatggca caccagaggt tcgcgcttgg cttgatgaaa tgactatcgc
      721 ggatattagc gtggttgttg tttcaaataa taaacattct cgtgttgagc gtgccgtttc
      781 acgctttggt gttgacttta ttagccgggc tttgaagcca tttgcttatg gtattgaaaa
      841 agccattgct cgttatggat ttgatcgcaa cgaggttatc atggttggag atcagctaat
      901 gactgatatc agagctagtc atagagctgg aataaaatca gttttagtca aaccacttgt
      961 tgcttctgat gcttggaata ctaaaattaa ccgctggcgt gaacgccgtg tgatggcaaa
     1021 attagaagag aaatatggta aattatcata tcaaaaagga atttaatgga agaattattt
     1081 tgtataggct gtggtatcca gattcaaact gaagataaag aaaaagctgg ttttacgcca
     1141 gctgctgctt tgaaaaaggg tatggaaaca gaagaactct attgtcagcg ctgctttaga
     1201 ttgaggcatt ataatgaaat tacagatgtc catattaccg atgatgaatt tttaagactt
     1261 cttcacgaag tgggtgatag tgatgctctt gtggttaatg tgattgatat ttttgacttt
     1321 aatggttcta ttattccagg tctatctcgc tttatttctg gtaatgatgt cttactggtt
     1381 gggaataaaa aagatatttt gccaaagtct gttaaggatg gtaaagttac tcaatggttg
     1441 acggaacgtg cacacgaaga aggtcttcgc ccattagacg ttatgttaac gagcgctcaa
     1501 aataaatatg cgattaaaga cttgattggg cgtatcaatg agttacgtaa tggtcgagat
     1561 gtttatgttg tgggggtcac taatgttggt aaatcaacct tgattaatgc gattatccaa
     1621 gagattactg gtaacaagga tgtcatcacg acgtctcgtt ttcctgggac aactcttgac
     1681 aaaattgaaa ttcctttgga tgatgggacg ttcatttttg atacgccagg aattattcac
     1741 aggcaccaga tggctcatta tttatcccct aaagagctaa aaatagtgag tcctaagaag
     1801 gaaatcaagc ctaagacgta tcaattaaat ccagaacaaa ctctcttttt aggtggtctg
     1861 gctcgctttg actttatcaa cggtgagcgt caaggattta cagctttttt tgacaatcaa
     1921 ctagaattac atcgtacaaa attagctgga gcagatgctt tttatgataa gcatgttgga
     1981 actttgttaa ccccgccaga taagaaagag ttgactgcat ttcctaaatt agttcgtcat
     2041 gaatttacaa ttgatcagaa aatggatatt gttttttctg gtctaggatg gattcgtgtt
     2101 aatggtcaaa aagactcaaa agcgatagtt gctgcatggg ctcctgaagg ggtcgctgtc
     2161 attgttcgta aagcgattat ttaaaaataa aaaagaagtt ggaaaaaaat gcttacaagt
     2221 aaacaaagag ctttcttaaa atctgaggct catagcttaa aaccgattgt acaaattggc
     2281 aaaaatggat taaatgacca cattaagact agtattcgtc aagctttgga tgctagagaa
     2341 ttgataaagg tcactttgtt gcaaaatact gatgaagata ttcatgaagt agcagagatt
     2401 ttagaagaag aaattgggtg tgatacggtt ttgaaaattg gtcgtatctt gattctctat
     2461 aaggtttctg ctaagaaaga aaaccgcaag ttgtccccta aagttaaagc aatctagtcc
     2521 ttttatttgt atagggactg gttttatgag acgaggacta ttgtcgcgag aattttggag
     2581 aaagtatggc attagaattg ttgacgcctt ttacgaaggt ggaattagag gaagaaaaaa
     2641 aagaaagcaa ccgcaaacag attgggattt taggagggaa ttttaatcct attcacaatg
     2701 cacaccttgt ggttgcagat caagttcgcc agcaattagg attagatcag gtgctattga
     2761 tgcctgaatg taaaccaccg catgtggatg ccaaagagac tattgatgag aagcatcgtc
     2821 ttcgcatgtt ggaattggct attgaagatg ttgaagggct agctattgaa acctgtgaac
     2881 ttgaacgtca gggaatcagc tatacctatg atacgatgct ttatttgact gagcagcatc
     2941 ctgatgtcga ttattatttt atcatcggag ctgatatggt tgattatttg ccaaagtggc
     3001 accgtattga tgaattggtc aaactcgttc aatttgttgg ggttcaacgt ccaaaatata
     3061 aagctggaac ctcttaccca gtgatttggg tagatcttcc tttgatggat atttcttcta
     3121 gtatgattag ggattttatt aaaaaaggtc gtcagcccaa ttatctctta cctaagcggg
     3181 ttttagacta cattactcaa gaaggtttgt atcaatgaca tatgaagatt atcttcctta
     3241 tagcaggacc gaactgttag caaaaattgc agagcagatg agccctaaac ggtttaaaca
     3301 tgtacttggc gtggaaaagg cagccttgtc cttggcagag tgttatggtt gtaacccaga
     3361 caaagcagga ttagcagctc ttttacatga ttatgccaag gagtgccctg accaggtctt
     3421 tttagactta attgacaagt accaattatc tccagaatta gctaaatgga ataataatgt
     3481 ctggcatggt atggttggta tttataagat tcaagaagac ttagggctaa aagacaaaga
     3541 tatcttgcga gctattgaaa ttcacaccgt tggtgctgct gagatgacct tgctggataa
     3601 ggtcttatac gttgctgatt atattgaaga aggtcgcatt tttcctttgg ttgatgacgc
     3661 tagaaaaatc gcgaagctcg atttgaatca ggctgttgcc tatgaaacag tgaacactgt
     3721 cgcttattta gcctcaaaag cgcagcctat tttcccacaa actctggata cctataatgc
     3781 gttttgcagc tatttaaagg aatactaatg gataatgata tgaggaataa aatgaaaaaa
     3841 gaagaactct taaaaattgt tgtggaagca actgatgaaa agcgtgctaa agatatttta
     3901 gccttggatt tagaggggtt aactagtttg actgattatt ttgtgattgc gagtgcaaca
     3961 aacagtcgtc aattagaggc tattgcggat aatattcgtg aaaaggtaaa agaggctggt
     4021 ggagatgcta gccatgttga aggtaatagc caagcaggct gggtcttgct tgatttgacc
     4081 gatgtggtgg tacatctttt tttagaagac gagcgttacc actataatct tgaaaaattg
     4141 tggcatgaag cgcctgctgt ggctctagat gcctatttag cttaatgtta caaagagacc
     4201 ttgtcaatac gacagggttt ttgaggatga taatggaaca taattatgaa aaatttgcgt
     4261 cagtttatga tgctgtgatg gatgattctc tatatgactt gtggacagat ttttcacttc
     4321 gacatttacc aaagtctaag agtcgaaatc gtttgttaga gttggcctgt ggaaccggta
     4381 ttcagtcagt tcgttttgct caagcaggtt ttgacgtgac tggtttagac ttaagtcaag
     4441 acatgctggc tattgctaaa aagcgtgcgc aatctgctaa aaagaaaatt gattttattc
     4501 aaggtaacat gctggatttg tcacaggtgg ggcagtttga ttttgtaacc tgctattcgg
     4561 attccatttg ctatatgcaa gacgaagttg atgttggcga tgtttttaaa gaagtttatg
     4621 atgttttagc aaacgatggc atctttattt ttgatgtgca ttcaacctat caaacggatg
     4681 agtgtttccc tggttattcc tatcatgaga atgcagatga ttttgcaatg gtttgggata
     4741 cctatgctga cgaggttcct cactctgttg ttcacgaact cactttcttt atccaagaag
     4801 acgatggacg tttttctcgc tttgatgaag tgcatgagga acgaacgtat gagttattga
     4861 cttatgatat tttgttggaa caagcagggt tcaagtcatt taaggtctat gcggattttg
     4921 aggataagga gccgactgag actagcaagc gttggttttt tgtggcatat aaatagaaga
     4981 aaaagtagcc tttttagcta taggatttaa tgaattatct tgaatgttac ttatatgaaa
     5041 agagttcatt aggcattaaa tgctattatc aaagcttaga agtattggag acattacgat
     5101 aaagaaagca ttttctatta tacgttgtgc ttaagcattt gatttaactc ttattagccc
     5161 tataaaagat tatttagtac aatttgagga gattctatga ctgttaccgg aattatagct
     5221 gagtttaatc cgtttcacaa tggacacaaa tatttgctag aaacagcaga gggactaaaa
     5281 atcattgcta tgtcaggaaa ttttatgcaa agaggagagc ctgctcttat tgataaatgg
     5341 attcgatcag agatggctct taaaaatggt gcagatattg ttgtggaatt gccctttttc
     5401 gtttcagttc aatcggcaga ctattttgct caaggagcta ttgatattct ttgtcaatta
     5461 ggaattcagc aattagcatt tgggacagag gatgtgattg attatcaaaa actgattaag
     5521 gtctatgaga aaaaatcaga gcaaatgact gcctatttat cgacgcttga agatacactt
     5581 agctatccac aaaaaacaca aaaaatgtgg gaaatctttg ctggagttaa attttcaggg
     5641 caaacgccaa atcatatttt ggggttaagt tacgcaaagg ctagcgctgg aaagcatata
     5701 caactatgtc ctatcaagcg tcaaggggct gcctaccatt cgaaagacaa aaatcatctg
     5761 ctagcttctg caagtgccat tagacagcac ctgaatgatt gggatttcat aagtcattca
     5821 gtaccaaatg caggtttact tataaacaat ccccatatgt catgggacca ttatttttca
     5881 ttcttaaaat atcaaatttt gaaccattct gatttaacta gtatttttca ggtcaatgat
     5941 gaattggcga gtcgtattaa aaaagcgata aaagttagtc aaaatattga ccacctagtt
     6001 gacactgttg ctaccaaacg ctatacaaaa gctcgtgtaa gacgtatttt aacctacatt
     6061 ttggttaatg ctaaggaacc tactttacct aaggggattc atattctagg gtttacctca
     6121 aaaggacaag cacatttaaa aaaattaaaa aaaagcagac ctctgattac tagaattgga
     6181 gcagaaactt gggatgagat gacacaaaaa gcagacagca tctatcaact tgggcatcag
     6241 gatatcccag aacaaagttt tggaagaata cctattataa taaaaaatga gaggctcaat
     6301 taaactctaa ttgagttttt tttgggggct tgactctaac attacgttga tggtttatac
     6361 ttcagttaat ccaatgagga aattttataa caataattaa aaaagtcagt caaaagatat
     6421 gctttcgaag aacaggctaa cgtttttaca agattatatc agtaatcatt ttgacaattg
     6481 tagtaatgga atgttgccaa aatttagaac gttgtgtgtt atgaatgaca agattttaaa
     6541 ggaatactaa ttaaacggga ggtcgtgaac cggaagctgt tgtcactcaa gcgccaaaat
     6601 ctgtctgtaa cataatattg atgtatggga acttaattat ttggttttta gtgtgatgct
     6661 taaaacgatt ttatatttct attttaccaa agcttttcaa agtgctataa taagggagtt
     6721 agagtcaata ttagtaacgt taatgttgac aatattcaat aaaatactat taaaaggaga
     6781 caaaaatggg acgtaaatgg gcaaatattg ttgctaaaaa aactgctaaa gatggagcaa
     6841 catcaaaggt ctatgccaaa tttggtgttg aaatttatgt ggctgccaaa caaggcgagc
     6901 cagatccaga gttaaataca gctcttaaat ttgtcattga tcgtgcaaag caagcacaag
     6961 tgccaaagca tgttattgat aaagcgattg ataaagctaa aggaaacaca gatgaaactt
     7021 tcgtagaggg acgctatgaa ggttttggtc caaatggttc aatgattatt gtggatactt
     7081 tgacatcaaa tgttaaccgt acagcggcaa atgtacgtac ggcttacggt aagaacggtg
     7141 gcaatatggg agcttcagga tctgtatcct acttatttga taaaaaaggg gtcatcgttt
     7201 ttgctggtga tgatgctgac agtgtctttg aacaattact tgaagcggat gtagacgtag
     7261 atgatgttga agcagaagag ggaacaataa cagtttacac tgccccaaca gatcttcata
     7321 aaggtatcca agcacttcgc gataatggtg tagaagaatt ccaagttact gaacttgaaa
     7381 tgattcctca atcagaagta gtattggaag gtgatgacct tgaaactttt gaaaagctta
     7441 ttgatgcact cgaatcagat gatgatgttc aaaaagtgta tcataatgta gcagattttt
     7501 aaattgacat agaataataa aaagagttga aatctatttc agctcttttt aagtgatgct
     7561 tttataagta agtaccaggt aacatagtcg ttgttagaag ataatgaaca atagtaaatc
     7621 agtatcaact tgataggaat caattattag tgaactctaa ttaaaaatgg taaactagac
     7681 acaagaacaa aaaggagaga taggatgatt aaaaaacaat atttaggaag agcaacaatt
     7741 gccctagcat caacccttgt gctagcagct tgtgggtcat caaaaacagc tgagtcagga
     7801 aatcagggga gttctaaaga agtcttattt gcaacggttg gaacaacagc tcccttttct
     7861 tatgaaaaag gtggtcaact aactgggtac gatatcgagg tggctaaagc agtctttaaa
     7921 ggatcggatg attacaaggt gtcctttaaa aaaacagaat ggtcttctat ctttacaggt
     7981 ttggactcag gaaaatacca aatgggtggt aacaacattt cctttaccaa agagcgttca
     8041 gctaagtacc ttttttctta tccaatcgga tcaacacctt ctgttttagt tgttccaaaa
     8101 gacagtgata tcaagagctt tgatgatatc caagggcata cgacacaagt tgttcaaggg
     8161 actacaagtg ttgcacagtt agaagacttt aataagaaac acagtgacaa cccggttact
     8221 ctaaaattca ccaatgagaa cattactcaa atgttaacca atttgagtga aggcaaggca
     8281 gatttcaaga tttttgacgc tccaacggtt aacgccatta ttaaaaatca agggttagat
     8341 aatctcaaaa ccattgaact cacctcaaca gagcaaccat ttatttattt tatctttagt
     8401 caagatcaag agaaattgca aagctttgtt aacaagcgta ttaaagagtt gactgctgac
     8461 ggaactctta gcaagcttgc caaagagcac cttggcggtg attacgtgcc atcagataaa
     8521 gagttgaaac ttcctacagc taactaaacc atctattaac cagttattca tctagaagac
     8581 tggtttttct gatcggaaac aatattatag tttatgaggt tatgttataa aaattgcaaa
     8641 tagccttaat caaaatgaga tgttaaagtg ctttttgaga agtgaatatt gtaagaagta
     8701 tgctttgggt tttagtcctc aaataccaag ttttttgttg actaaacaaa taaggatggt
     8761 tagcatagca tatagtttaa aactatggta tatgctagcc attatcaatt tgaaaactat
     8821 atctaattaa gatacaataa tgatcgtaaa caaaatgaat cgaggataac gctatgtctt
     8881 ttaaaaaatg gattggaata gtcggaatcg ctttggcatc aactgtattg gttgcttgtt
     8941 ctgaaaaaca agatgataaa aacactctaa ctattggggt gatgacaaaa acagaatctg
     9001 atcaagcgag atgggataaa gttgaagaat tattaaaaaa agacaatatc actttgaagt
     9061 acaaagaatt tacagattac tcgcaaccta ataaggcagt tgctaatggt gaagtcgata
     9121 ttaatgcctt ccaacactat aatttcttaa ataactggaa taaggaaaat aaggaacatt
     9181 tggtggccat tgctgatacc tatatcagcc caattaacct tttctctgga accagtcaag
     9241 atgggaaggc taaatacaaa tcagtagctg atctgccaaa tggtgctcaa attgcagtac
     9301 caaatgatgc gaccaatgaa agccgtgccc tctatgtgct gcaatcagct ggcctcatta
     9361 aattgaatgt gtctggtgat caattagcaa ccattgccaa tatctcagag aacaaaaaga
     9421 aattagatat caaggaatta gatgctagcc aaacggcacg tgctttagta tctgctgatg
     9481 cagctgttgt caataatagt tacgctgttc ctgcaaaaat tgactacaaa acctctcttt
     9541 tcaaagaaaa agcagatgac aattcaaaac aatggattaa cattattgca ggtcaaaaag
     9601 attgggaaaa atcagagaag gctgatgcta ttaaaaaact catcaaggcc taccaaactg
     9661 atgaggtgaa gaaagtcgtg gaaaaaactt caaatggtat agatgtatcc gtatggtaaa
     9721 ttttagccat tgttataaca agagtgtggt tgtgtttaaa acacatgctt tcttgcatgc
     9781 ttgaggaaga gtttacgatt aacttacctt tagaaagcta tttaagacct tttccctttt
     9841 aggatttagg aaccttggga agactattgc atgttatctt aatagtcatg attatgcagg
     9901 cgatgaaaac attgctatcg tagattactg tcgccatatc gtactaatag aggagttatt
     9961 aaaatcttat gaatgaagca ataattcaat tagatcatat tgatattacc ttccgtcaaa
    10021 aaaaacgggt tatcgaagct gttaaagatg tcacggttca tatcaatcaa ggagatattt
    10081 atggcattgt tgggtattca ggtgctggga aatcaactct tgtgcgtgtg attaacctgc
    10141 tacaggcacc aacaaacggg aaaatcactg ttgatgggga tgttaccttt gaacagggga
    10201 aagttcagtt atcagccaat gcccttcgtc aaaaacgacg tgatattggc atgatcttcc
    10261 aacatttcaa tttgatggcc caaaaaacag ccaaagaaaa tgtagcattt gcgctccgcc
    10321 attcatcgtt aagtaagact gagaaagaac ataaagttat cgagctgcta gaacttgtag
    10381 gtttatcaga gcgagcagat aactaccctg cccagttatc gggtgggcaa aaacaaaggg
    10441 tggctattgc gcgtgctcta gctaacgatc caaaaatttt gatttcagat gaggccacat
    10501 cagcactaga tccaaaaacc actaaacaaa ttttggcgct cttgcaagaa ttaaaccgca
    10561 aacttggcct taccattgtt atgattactc atgaaatgca aattgttaag gatatttgta
    10621 atcgtgttgc tgttatgcaa aatggtgttt tgattgaaga aggttctgtc cttgatatct
    10681 tttcaaatcc aaaagaagcc ttgacacagg aatttatcac aacagctaca gggattgatg
    10741 aggctttaga aaaaattaac caacaagaca ttgttaaaca tttgcctgca aatgcccttc
    10801 tagctcagtt gaaatatgca ggaacttcta cggatgagcc tctacttaat agcatttacc
    10861 gtcaatttga agtgacagct aatattttgt atggcaatat tgagatttta gatcatattc
    10921 cagttggtga catgattgtt gtcttggaag ggcaagctga aaatattctt gcggctgaga
    10981 aagccttgca tgaagctggt gttgatgtta gtattttaaa gagaggagcc tagatgtcac
    11041 agttaattca aacttatttg ccaaatgttt atgaactcgg atggtctgga gatgctggtt
    11101 ggggcttagc gatttggaat actttataca tgaccattgt gccttttatt gttgggggtg
    11161 ctattggtct cttattaggc ttactattag ttttaacagg accggacggt gttattgaaa
    11221 acaaaacgat ttgttgggtt attgataaag ttacctctat ttttagagcc attccttttg
    11281 ttattttgat tgctatttta gctagcttta cctatttgct tttaagaaca actttagggg
    11341 caacagcggc cttggtacct ttaacctttg cgacttttcc tttttatgcc cgtcaggtcc
    11401 aagttgtttt ttcagaatta gacaagggtg ttattgaagc agcgcaagct tcaggtgcta
    11461 ctttctggga tattgtcaaa gtgtatctca gtgaaggttt accagatctt attcgtgttt
    11521 ctacagtcac cttaatttct ttagttgggg aaactgccat ggcaggagct atcggtgctg
    11581 gaggattagg aaatgtagcg atttcttatg gttataatcg ttttaacaat gatgtgactt
    11641 gggtagcgac tattattatt cttttaatta tttttgctat ccaatttatt ggtgatagct
    11701 tgactagaag gtttagtcat aaataaacga aacaacaccc taagttttta cttagggtgt
    11761 tgttgtttag atgatgtcat tagcttttct tcgttttact tagtataagc cctattaaaa
    11821 aaccaatagc agcaaagata atccatccca ttgagaattg ccctagtgga acagtttttt
    11881 ggaaaaaagt tacaacggct tctggtaaat gaaataatcc agtcatttgt gatagtgtta
    11941 ggagtgcatc aaatatggca ggaataaagg ttagaccaat tgtagttcga tagacaatag
    12001 gatcattatt gaagcatttt tgtgccaaaa caaggaaaat taaatcgact gttaatgggt
    12061 ataaaaggaa taaaacagga gctgaccagt tgataatgac tgataagcca ccaaaataaa
    12121 agaaagctga tagtaaagta aagatagttg cccaagcaat atgagataaa gtaggcacta
    12181 atttatggaa gtattcagca cttgacgtga ttaagcctgt tgaagtggtt agacaggcca
    12241 ggaaaatcac aacagctaga aatgattgtc cgatgccacc taggtaaaaa cgagaagcat
    12301 gacttaagat ttgaccgcca ttaactggat taccatgaag ggtaaagctg ccatcactaa
    12361 aaggaaataa tgattgtgat gttgctccaa tacgaccgac aaagatatag acaagtgcta
    12421 atagcaaaat ggcaatagcc ccagaaataa gtgttatttt ggtcacttct ttgtccgtct
    12481 tagcgccaaa ttgtttggta gcctcaatga ctaaaatagc aaaaacaaga gaagctagtg
    12541 catccatagt gccataacct tgaattaatc ctgctataaa aggaaaatct ttaaaggcat
    12601 tattaacacc gaccccagcg ttaaaagcat caccgtaatt tccagcagga tggacaaagg
    12661 acgtgataac caaaatagaa ataacaacta acaacgttgg cgttaaaaat tttccgatat
    12721 tttcagctag cttactaggt ttgatagcaa ggaagtagga cagaccaaaa aataatatag
    12781 cataaatagc tttattggtt gtattatctc ctaagatagg agcgataccg actgaaaaag
    12841 aagtggctcc tgttcttgga atagcaaaaa atggaccaat agataaatac aaaatggaag
    12901 aatagaagat tgcataccat ttagagatgg ggcgtgccaa actttcaaca tcgcctgatc
    12961 cagatttagc aacagcaatg acaccgagta aaggcaagga gacaccagtt aaacaaaaac
    13021 caatgataga ccatagaatc tgatgaccgg agtagatgcc taaaaaagct gggtaaatga
    13081 ggtttgctgc tccaaaaaat agtgcaaata gcatgaatcc aatgacgata tatacatttt
    13141 tttgtttcat ttataaatag tctttctatt gatactaatc cgaagattct aacaatttta
    13201 attatattat gtgtcaaaat aacaacaaag gttattatat ctaagattac ttcgatagtc
    13261 aatagaaatt gactgaaaat tcttagcaca aaaaatggtt aagatatgta gcttattcga
    13321 tttgacgaat agatagaatt atattattat aaaaaacatg taactttagt aaggatgtaa
    13381 cgtatgaaaa aaatatatga tttatgggtt agggttagtc taatcaaaaa aataggtatc
    13441 ggtgttgtaa taggagtcat gttgggcatt ttagctcctg atcttacagg ttttagtatt
    13501 ttaggaaagt tatttgttgg tggtttaaag gctatcgcac ctttgcttgt atttgctttg
    13561 gtttcccaag ccatctccca tcagaaaaaa gggagacaga ctaatatgac attaatcatt
    13621 gttctgtatt tatttggtac ctttgcgtca gctttagtag cagtactgac agcttatcta
    13681 ttccctttga cgttagtgtt aaatacacct gtaaatacag aattatcacc acctcaaggt
    13741 gttgctgaag tttttcagtc acttctatta aaattagtgg ataatccgat caatgcttta
    13801 gctactgcca attatattgg tgtgctatca tgggcaatta tttttggact agcattaaag
    13861 gctgcaagtc aagaaacaaa gcatcttata aaaacagcgg cagaagttac ttcacaaata
    13921 gttgtttgga tcatcaatct ggcacctatt gggattatga gtctggtgtt cactacgatt
    13981 tctgaaaacg gtgttggaat cttatctgat tatgcttttt tgatactagt tttagtagga
    14041 acaatggttt ttgtcgcctt agtggttaat ccacttattg cggttttgat tacacgacaa
    14101 aatccttatc cccttgtctt gagatgttta cgtgagtcag gtcttacagc atttttcaca
    14161 cgaagttctg cagccaatat tccagtcaat atgcaattat gccaaaaaat tggattgagt
    14221 aaagatactt attcagtgtc aattccactt ggagcaacta ttaatatggg tggggcagca
    14281 attaccatca atgtcctaac gcttgctgct gtacacactt ttggtattcc tattgatttt
    14341 ctaacagccc tcttacttag cgttgttgct gctgtctctg cttgtggtgc ttctggtgtt
    14401 gctgggggat cgttgttact tattcctgta gcatgtagtt tgtttggcat ttcaaatgat
    14461 cttgcgatgc aggtggttgg tgttggtttt attgttggtg ttatccagga ttcttgtgag
    14521 acagccttaa attcgtcaac cgatgttctt tttacagcta ttgctgaaaa tgctttttgg
    14581 aaacgtaaaa aagcctagct aggtttaaca tagtaaaaaa catccttgga aaacgccaag
    14641 gatgtttttt tattatttaa gatagccaag ataatcaaat ttttcaaagg tgtggtcatt
    14701 agcgatggcc acaatgatag tattcggttc taaaggttca aaaggtttga cattagtatc
    14761 taaggtttta acttcttttt gacgcatgcc aatcacattt aactcatatt tacgacgaac
    14821 atctagttcg gaaagagatt gtccttccca gcttttagga atgacaaatt caatcatcga
    14881 aataccatgt tccaaataga tgatgctttc aatatgacgt cttaacagat ttgaagctac
    14941 acgttttcca gaatcacgtt caggggtgat gactttagtt gctccgatgc catatagaac
    15001 ttcttcaaaa attttatttt tagccttggc aataatggtt ggaacaccga gttttttaca
    15061 gtgcatgact gcaagaacag aagattccaa gttattccct gaagcgataa cgacagtatc
    15121 acaatgttca acccctacag ctaatagaaa ttctttgtca gtaatatctc caacagcggc
    15181 tttagtgacc aagtcggcca cctctttgac atgactttct ctgatatcaa tagcaataac
    15241 gtcttgatca aagttactta attctctggc aacagtacgg ccaaaaatac caaggccaag
    15301 aacgccgaca gttttacgtt ttaacatgtt ttctccttaa cccactagaa tatcagtagt
    15361 ggcatattga atggtttttt cttttcgttg aatcagacta atgaggacag taattgggcc
    15421 aacgcggccg acgaacatca agacaatgac aataagacgt ccagcagtag acaattgtgg
    15481 tgtcaaatcc atagataccc caactgtcgc gatggcagaa atagattcaa ataagagtgg
    15541 tataggagcg atatgaggct ccacgctaag taataaaata aaacctatca taagaactgc
    15601 aaaaaagaag ataagaactg tcatggtctg cttaattgtc ttatttgcga taattcggtt
    15661 acgaaaggta acttctgatt gccctgaaag ttccgcttta aagagtaaga aagtaatggc
    15721 agcagtcgtc actttaatcc caccagctgt tccaccagga gcaccaccaa taaccatttg
    15781 aatcatataa agaatgttag ttggtgctag ggtatcgtta taagagattg ttgcaaagcc
    15841 agctgttctc atagtgactg tttgaaaaaa tgaaaccata agttgctgat gtaaactaaa
    15901 attggcaatg gttttgctgt tatctttttc taaaaaccag gttaagaagg ttccaagaaa
    15961 aagaataaca gctgtggttt gtagtactag acgagactga ttggataatt tacgaaaagt
    16021 tgccccataa caatgaggtc tttcaaaaaa gtatttttta aaagctactc ctaaatcaac
    16081 ccaaaccgca aaaccaagtc caccagagat aatcaagaac gtaatgataa catttaatgt
    16141 aggatttaac ataaagtctt ttaaactaga agatcctaaa ttgtcaaaac cagcgttaca
    16201 aaatgccgac acagctaaaa aaatactatt gaagatacca tttttccacc cgaagcgggg
    16261 gataaagtca atcatgataa ctatcgcagc aaaggcttct agaccaaagg ttactttata
    16321 agcaaaaaaa aggtagtgct ttaaatcttt gctatcacct cgatttaacg ctgattggag
    16381 caaggtttga tcgctcaatc gcatttttcg cttgagggca aaagtactca cagctattaa
    16441 cgtcaccaag ccaagaccac caatctgcat tagtgccata gcaatggttt gtccgatacc
    16501 gttatacact tcagcgacgg gaacaacaga aagtccagtc acacaaacca tggaaaccac
    16561 attaaagaaa tgatcaagat agacggtatt aggaccattt tgataatggg taaagggcat
    16621 ggataacaag agagtcccaa tcagaatcac aatggcaaaa ctaaatgtta agcgctgtgt
    16681 gactgaaaga gatttgataa aagagcgttt catgtttcct ccagacataa tatctcctac
    16741 tataataaca aaaataagtt aaaaaagcta agtttcatct tagcctttgg tactatttta
    16801 tagaggtttt ttgttaggca agccagcttt tcttggatac ttgttaggtg tttccttttt
    16861 cttctcaaca atggtgatga agcgagaatc tccatttggc aattggtagc tatggttttt
    16921 aatgacttta ccaaaaagaa gacaaagagc attcttagct tcttctaact cttggtcagc
    16981 agcttgtgcc tttaaggcga ttaattttcc tccaattttt aaaaagggga tggttaattc
    17041 agatagaacc tgcatccgag caaccgctct ggcagtaatg acatcaaatt gacctcgaaa
    17101 ggccttgtcc tgtccgaaat cttctgctct accatgaaaa aaatggacat tttccaagcc
    17161 caattcctga gcaaggagtg tcagaaaaga aatccgctta ttaagagaat caataatggt
    17221 aacctcaagg tttgggaaaa gaattttcat gggtaggcta ggaaaaccag ctccagctcc
    17281 aatgtccaat aatttgattg gttcattagc taaaaagccc tgtaaaatag gagcgatgga
    17341 atcataaaaa tgcttgaggt aaacctcatt ttcttctgta atagctgtta aattaatttt
    17401 agtgttccat tccactagta atttgaagta ggtgtcaaat tgttcttttt gtttcgatga
    17461 taaggaaaaa ccatcttcct ctagtgttcg gtaaaagtct tggggtgtca tttgtatcct
    17521 ctgtttttga tagttgttac cattttatca taaaatagcc cataacaaaa tccaataaat
    17581 catcagaaat aacacctcat tacttgctat tagcctagaa attgctataa ttgagacaca
    17641 aagattaaag gagacccact atgccaacag ttttgattat cttagtcgtt ttaggagtgc
    17701 ttgcgctatg gttaatgatt agttacaata gcctggttaa atctcggatg cacacaaaag
    17761 aagcttggag tcagattgat gtgcaattaa agcgtcgtaa tgacttgatt ccaaatctta
    17821 ttgaaaccgt aaagggatat gctagctacg agcaaaagac atttgaaaaa atcactgatt
    17881 tgcgtgcgcg tgttgcgaat gcctcaactc ctcaagaaac catggcggct tctaacgaat
    17941 tgagtaaaca agtgaccagt ttgtttgccg ttgctgaaaa ttacccagac ttaaaagcta
    18001 acgaaaactt cttgaaatta caagaagagt tgaccaatac ggaaaataaa atctcatatt
    18061 ctcgtcaact ctataattca acaacgtcta attacaacct tcaattagaa tctttcccaa
    18121 gcaatatcgc tggtaaatta tttggtttta aaccaagtga attcttacaa acaccagaag
    18181 ctgaaaaaga agttccaaaa gttgaattta acttttaaat atgaaattat catctagtag
    18241 gcaatcataa gagaaaggag aattatgctt tatcaacaga tttcacaaaa taagcaacga
    18301 acagttgttt tattagttgt tttcttcgct ctcttagcac ttattggagc ttcagcaggc
    18361 tatctgctgt tagataatta tgccatgggc ttggttcttg ctcttgtcat tggggtgatt
    18421 tatgctacca gtatgatttt tcaatccacc agtcttgtaa tgagtatgaa caatgctaga
    18481 gaagttacag aaaaagaggc tccaggcttc ttccatattg tcgaggatat ggctatggtg
    18541 gcccagattc cgatgccgag agtttttatt attgaagatc cttctttaaa tgcttttgcg
    18601 acaggatcta gccctcaaaa tgctgctgtt gcagcaacga caggtttact tgaagtcatg
    18661 aatcgtgaag aacttgaagg tgttatcggc catgaaatta gccacatccg aaattatgat
    18721 atccgtattt cgactattgc tgtagctttg gcgagtgctg ttaccgttat ttctagtatc
    18781 ggtgggcgta tgctatggta tggtggcggt tctcgcaggc aaagagatga cggagatgat
    18841 gatgttttaa gaatcattac attacttttg tcgttattat ctttgctttt agcgccccta
    18901 gtagcaagtt tgattcagtt ggctatttct cgtcaaagag aatatctagc tgatgctagt
    18961 tctgttgaac taacaagaaa tccccaaggt atgattaagg ctcttgaaaa attgcagtta
    19021 tctcagccaa tgaagcatcc tgttgatgat gctagtgcag ccttgtatat taatgagcct
    19081 cgcaaaaaaa ggagcttcag ttcattattc agcacccatc ctcctattga ggagaggatt
    19141 gaaaggttaa aaaacatgtg agcgtttggg gtttttgctc aagcctcact tttttatatc
    19201 tttgggtaga taatctaaaa ttgcaggaat tatcaaaagt atctgaacaa aaagaaaaaa
    19261 atgagtgaaa caatggttaa aaatagaatg atttaaatct taaaattaaa aaacgtcaga
    19321 aaataaatgc aaaactattg acaaatcttt tagatagtag taaaaataaa tgagagtttt
    19381 attaggagaa gatgatgtta gctatttccg aaatcagaaa acacccagac ggtctctcgt
    19441 ttgatcgttt atgtgatgtc aaaagtatgt tacttgagcg tgaccaacag attattgaca
    19501 taaaggcagt taaagctgtc ggtaatgttc gctatgataa ggggctttat ctgttagatt
    19561 atcaattgag ttacgaagtg atattaccgt ctagccgttc tatggttccg gtctgtttaa
    19621 gtgaagtcca acacattcaa gaattattta tagaggcgac agatttagct gataagaaag
    19681 agttggttga agacaatctg gtattagttt tagacaaaga cgctattaac ctcgaagaaa
    19741 gtattgtgga taatatctta cttgctattc cgctacaggt cttgacagag gaagaaaaga
    19801 aatcaaaaga gttgccagca ggtcaaaatt gggcagtttt gacagaagaa gactaccagt
    19861 gtctaaaaga agaaaagcaa aaagaaaata atccttttgc tagcttgcaa gggttgtttg
    19921 atgaataaaa ctgaatatta aagatgtctg taatttttat ttgaaaaaac agctattctt
    19981 tgatatactc tttagagaat atggttactt atctaaagta gaaggtattt tgaccataga
    20041 gggcaaagaa ggtaatgact attagatgct tcatatttta ttcgctagaa gactatttga
    20101 ccattagaac tgaaatagtc taggatatga gatggatttc atagttttct ttctgggaga
    20161 aaaagataga ttaagaggat aagggttggt ataaatgaca aagaagattt taattattga
    20221 agatgaaaag aatctggcta gattcgtttc tcttgagctg caacatgagg gttatgaagt
    20281 cattgttgag gtcaatggtc gtgaagggtt agaaactgct ttggaaaaag agtttgattt
    20341 aatcctgctt gacttaatgt taccagagat ggatggtttt gaagtgaccc gtcgtttgca
    20401 aaccgaaaaa acaacgtata tcatgatgat gactgcgcgt gattctatta tggatgtggt
    20461 tgcaggttta gaccgcggtg cagacgacta tattgttaaa ccgtttgcca ttgaagaact
    20521 acttgcccgt attcgtgcta ttttccgccg tcaagatatt gaatctgaga agaaagtgcc
    20581 tagtcaaggc atttatcgag atctagtttt aaatccacaa aaccgttcag ttaatcgtgg
    20641 cgacgatgag atttctctca ctaaacgtga atatgatttg cttaatattt tgatgactaa
    20701 tatgaatcgt gtcatgacac gtgaagaatt attgtcaaat gtttggaaat atgatgaagc
    20761 cgttgagact aatgttgtag atgtctatat tcgttatctc cgcggcaaaa ttgacattcc
    20821 aggcaaggaa tcttatatcc aaacagtgcg tggcatggga tacgttattc gtgagaaata
    20881 agtcatatgg aaaatcagaa acaaaaacag aagaaatata aaaactcgtt accaaaacga
    20941 ctatctaata tcttttttgt tctttttttc tgcattttct ctgcctttac actgattgcc
    21001 tatagttcaa caaactattt cttattgaag aaagaaaagc agtcagtctt tcaagctgta
    21061 aatattgtta gagttcgtct ttctgaggtg gactctaatt ttacattaga gaacttagca
    21121 gaagttttgt acaaaaacga taaaacacat ctgagaattg atgacagaaa gggcagtcga
    21181 gtcattagga gtgagcgtga tatcacaaat actctagatg cgaatcaaga tatttatgtc
    21241 tataacattg ataaacagat gatttttacc acagataacg aagaatcatc tcctggcttg
    21301 catggtccta tcggtcgtgt gtatcacgac catatcgaag atcagtatcg tgggttttcc
    21361 atgacacaaa aggtatattc taatcggact ggaaaatttg tgggctatgt tcaagtcttt
    21421 catgatttag gcaattatta tgtcattaga gcaagactgc tgttttggct actagttgtt
    21481 gagttatttg gcacaagctt agcctattta atcatcttaa ttactacgcg gcgctttttg
    21541 aagcctttac acaatttaca tgaagtgatg cgtaatatct ctgaaaatcc taataattta
    21601 aacctgcgct cagatatttc gtcaggagat gaaatcgaag aattgtctgt tatctttgac
    21661 aatatgttag acaaattgga gacacatact aagttgcaat cacgttttat tagtgatgtc
    21721 agccatgaat tacgaacacc ggttgcgatt attaaagggc atattggtct cttacaacgt
    21781 tggggtaaag atgacagtga tattcttgaa gaaagcttga cagcaacagc gcatgaggct
    21841 gaccgtatgg caatcatgat taatgatatg ttagacatga ttcgcgtaca aggctcattt
    21901 gagggacatc aaaatgatat gacagttttg gaagattcta ttgaaactgt tgttggtaat
    21961 tttagagttt taagagaaga ttttatcttt acatggcagt cagaaaatcc aaaaacgata
    22021 gcccgtattt ataaaaatca ttttgagcag gctttgatga ttctgattga caatgctgtg
    22081 aagtattccc gtaaagaaaa gaaaatcgcg attaaccttt cagtgactgg caaacaagaa
    22141 gctattgtta gagttcaaga taaaggcgaa ggaatttcta aagaagatat tgaacatatc
    22201 tttgaacgct tttatagaac ggataaatca cgtaatcgaa caagtaccca ggctggatta
    22261 gggattggct tgtctattct caagcaaatt gtagatgggt atcatttaca gatgaaggtt
    22321 gaaagtgaat taaatgaagg ttcagtgttt atcttacata ttcctttggc ccagtctaaa
    22381 gagagttaga gtagcttaag gcattgttaa tgtgacaggt atagtatgta atcattagat
    22441 aatagtagca gtcttttgcc acaactggtt agaagctgat gctatttttt tagcaatgat
    22501 ggatgacatg aaagaaatac tgtcaatcgc gatgcctttt gttatccttg agaatatggt
    22561 aaaatagtgt attagattaa tttgatagaa ttggggtgtt tgcgtgcgtt gtccaaaatg
    22621 taattaccat aaatcgagtg ttgttgacag tagacaagct gaagacggca acaccattcg
    22681 tcgtcgaaga gaatgtgaac agtgtcatac tcgctttact acctttgagc gtgttgaaga
    22741 actcccttta ttagtcatca aaaaagatgg cacacgagag caattttcta gagataaaat
    22801 attaaatggg gttgtccaaa gtgcgcaaaa acgacctgtc tcgagcacag atattgaaaa
    22861 tgtcatttct cgtattgaac aagaagttcg aacaacctac gaaaatgaag tgtcaagtac
    22921 tgctattggt aatttagtga tggatgagtt ggccgaactc gatgaaatca catatgtacg
    22981 ctttgctagt gtctacaaga gcttcaagga cgttgatgaa atcgaagaac ttttgcaaca
    23041 aattacgaat cgcgtacgcg gaaagaaaaa acgtttaaat aatgatgaaa ccaattgata
    23101 cttttacata tctaaaacgc aacaaagtaa ctcttgattc ggtgacttta atacagttgt
    23161 actttccaat tattggaagt gacgcagtct ctatctatca atactttatt cacttttttg
    23221 acgatggttt acaacgtcat aaattcagcg atattttaaa tcacctacag tttggtatga
    23281 aacgttttga agatgctctt gccatattga cagcaatgga attagtgagt gtgtatcagc
    23341 tatcagatac atatctcatt acgttgcacc agccgcttag ccgtgacttg ttttttcaac
    23401 atccagctta ttctcgatta ttagaacaaa agattggaga ggtagctgtc tctgagttgc
    23461 aggtaactgt cccaagtcaa gcaagaaata tttctaagcg attttcggat atttttgggg
    23521 tgcaagaaaa tttgacgaac gtacctcaaa agccacaaaa gaattttgac ctttcaagtt
    23581 tccagcaatt aatggttcgt gatgggttac aatttgaaga taatcaaaaa gatatcatta
    23641 gcctttacag tattgctgaa cagtatgata tgacgtggtt tgatacttat caaatagcta
    23701 aggcgacggc tgttaatgga aaaattcgac ctgaacgctt attggctaaa aaaaatcaaa
    23761 gcatgacaaa accaagcaaa gaaaattttt cacaggctga gcaaattatt ttgcgagaag
    23821 caaagcaaga cagtgcttta gtctttttgg aaaaaattaa aaaggctaga cgtgcaacga
    23881 ttactaagga tgaacgcatt ttattgcaaa cattggccaa aatgaatttt cttgatgatg
    23941 ttatcaatgt catggtgctt tataccttta ataagacaaa atctgctaat ttacagaaga
    24001 gttatgtctt aaaaatggcc aatgattttg cctaccaaaa ggtgtcaacg gctgaagaag
    24061 ctatagtggt tttgcgagcc ttcacggatc gtcaaagttg tcggcaatca aaagtaaaaa
    24121 caagtcaaag caatgtgcct aagtggagca atcctgatta ccaagagaca acaagtcaag
    24181 aagagcaggc gaaactagat cagttcaaac aggctgcttt gaagaggtta gaaaacctag
    24241 gaaaaggggg tgactagatg gaaaagattg gagaaaccat ggcgaaattg ggtcaaaaca
    24301 ctcgtgttaa tagcgaccag ttgattcaaa ccattttagc ggatcctgaa gtagcaagct
    24361 tcatcagtca acatcactta tctcaagagc aaattaacct tagcttatct aagttcaatc
    24421 aatttttggt ggaacgccag aagtatcaac tcaaagatcc ctcttatatt gctaagggct
    24481 atcagcctat tctagctatg aatgagggct acgctgatgt gtcttatttg gaaaccaaag
    24541 aattggtaga agctcaaaaa caggcagcta tctctgaacg gattcaactg gttagtttgc
    24601 caaaatccta tcgccatatt catttatcag atattgatgt taataatgcg agccgtatgg
    24661 aagccttctc tgctatttta gattttgtgg aacaataccc atcagcagag caaaaaggct
    24721 tatatttgta cggagatatg ggaattggca agtcttactt gttggctgct atggcccatg
    24781 aattgtctga gaaaaaaggt gtgtcaacga cccttctaca ttttccgagc tttgccattg
    24841 atgtaaaaaa tgccatttca aacggctctg ttaaagaaga aatcgatgcg gtcaaaaatg
    24901 taccagtgct cattttagat gatattggtg cagagcaagc cacttcttgg gtccgtgatg
    24961 aggtgttgca ggtgatttta caataccgta tgttagagga attgccaacc ttctttacct
    25021 ctaattacag ctttgcggat ttggagcgaa aatgggcaac catcaaagga agtgacgaaa
    25081 cttggcaggc caaacgtgtc atggaacgcg tgcgttattt ggctagagag tttcatttag
    25141 aaggggctaa ccgccgttaa gtttgagata gcaatcaaga agaatagcta cacgtatgag
    25201 tgagtgaaag aaaaggagaa tcatggtttt acctaccgtt gccattgtgg gccgtccaaa
    25261 cgtgggcaag tccaccttat ttaatcgaat cgcaggagag cgcatttcaa ttgtagaaga
    25321 cgttgaaggg gttactcgtg accgtattta tgctactggg gagtggctta accgccaatt
    25381 ttcattgatt gatacaggtg gtattgatga cgttgatgcc ccgtttatgg agcaaatcaa
    25441 gcaccaggct caaattgcca tggaagaagc tgatgttatc gtttttgttg tttctggcaa
    25501 agaaggggtt acggatgcag atgaatatgt gtctaaaatt ctgtatcgaa ccaatacccc
    25561 agtcatttta gctgttaata aggttgataa tcctgaaatg cgtaatgaca tttatgattt
    25621 ttattcactt ggtttagggg atccctatcc agtttcttct gttcatggta tcggaacagg
    25681 ggatgtcttg gatgcgatcg ttgaaaactt gccagtagaa gaggctgaag aaaatgatga
    25741 tattattcgc ttcagtttaa tcggtcgtcc taatgttggg aaatctagct tgattaacgc
    25801 tattttaggt gaggaccgtg ttatcgctag ccctgtcgca gggacaacac gtgacgctat
    25861 tgacacgcat tttacggatg ctgacggtca agaatttacc atgattgaca cggctggaat
    25921 gcgcaaatct ggcaagattt acgaaaatac agagaaatat tctgtcatgc gtgccatgcg
    25981 tgccattgac cgctccgatg tggtcttgat ggttatcaat gctgaagaag gtatccgtga
    26041 atacgacaag cgtatcgctg gctttgcaca cgaagctggt aaaggaatga ttatcgtggt
    26101 taacaaatgg gataccattg acaaggataa tcataccgtt gctaagtggg aagccgatat
    26161 tcgtgaccaa ttccaatttt tgacatacgc tccgattatt tttgtgtcag ctttgacgaa
    26221 gcagcgcctc aacaaattgc ctgacttgat taaacgtatc agtgagagtc agaataaacg
    26281 tatcccatct gctgtcctca atgatgttat catggatgct attgccatta atccaacgcc
    26341 aacggataag ggtaaacgtt tgaaaatttt ctatgccact caagtgtcag taaagccacc
    26401 aacatttgtc gtctttgtta acgaagaaga attgatgcac ttctcttatc tacgcttctt
    26461 ggaaaaccag attcgcgcag cctttacctt tgaagggaca ccgattcatc tgattgctcg
    26521 caaacggaaa taagaaatga acatcaacta aaatgctgac ctaagaaata atctcatcat
    26581 tgataaggac tgtgttgtgt atgttacagg agacagtcct ttttataata cctttaaggg
    26641 tgtagacgga agattagtag caaacaaaga aaaaggattt tgacaagaaa tatcagtcgc
    26701 tttttgctat aatgaaagga taagcaaaaa ggtggaaaaa tgatggctag attaattcca
    26761 ggacgagtaa ggaatgaagg tattaagctt tatgagcaag gtttagtctc attccaagat
    26821 gataataaag gcattcttca aatagaagtg gagacttatc aggttcaata tggagcagat
    26881 gatgaggata tcacttgtca atgcgacaca tttcatatga aacattattg caagcatatt
    26941 gcagcagtcg agtatttttt aaaaaatgat caaaaaggta agcttttttt aaaacagtta
    27001 acaaatcaaa caaaaatcaa agaaacaaca aagaaaatga catcttttgg tagtctcttt
    27061 ttagatagct tagccatgaa tgaagatgat tctgttaaat acaggctgtc tgctcttggt
    27121 agtcgaagcc ctttttcgtc agattactgg tggagtctga aaatcaatcg tttaccagat
    27181 gatcgttctt atgtgattcg agatattaaa ggctttttgc agcttattaa aaaagaaggc
    27241 ttttatcaga ttggaaaaaa ttattttgaa caactttcat ggctgcagtt tgacccatcc
    27301 agtcaagacc ttattgagtt tttatggcgc ttagcatcta atactgacaa aggggacaac
    27361 gagaacattt ttccaaatca tgcaaggcat ttgcgcttac ctagtggttt ttttgaagaa
    27421 ggtattcact atttgacgtc actttatgat tttacttttg aggggccttc tcaaacttat
    27481 catcatcttt ttgtccgttc tttggaagca gaggcaggcc tttatgagtt taaagtggaa
    27541 gtgcatcgca aatctattga attgcaaatt gctgaaaaaa atgtgcaata cctctttgat
    27601 aatgactatc ttctttatca agataccttt tatcacttga cgttaaagca acgaaaaatg
    27661 gttcaggcta ttcgtagtct gcccattgag gccgacttgg ctaaacatat tcattttgat
    27721 ttggatgatc atgcgaaatt agctgcaagc ttatcagatt ttaaacagat cggtctagta
    27781 gaggctccta aaagctttgc tattagagac tttgaggtga cttttcaatt tgatttgtta
    27841 aatcgagatg aaatcagttg tcagcttatg tttgattatg gcaattacca agttagtgac
    27901 aaagcaagtt tagaagcact tccttttgct agtcatttaa aaaaagaaga aaaaatcaat
    27961 cgttctttac ttgcttttgg cttctcgcca caattttact caaaaaagcg actaacaagt
    28021 gcaaaagagc tctatacttt ttttgaagaa acagttccat gttttgagcg cttaggtaat
    28081 gttgcgttga gtacagctat ccaagcatta caagtgaaag aaatgcccaa gatcgctatt
    28141 agacgcaatc agggattact agatatttcg tttgattttt caaccattat tgaaaatgat
    28201 attgaccaag ctgttacagc tctttttcaa aataatcctt attttgtgag tcaaacaggt
    28261 caattagtgg tttttgatga tgaaactcaa aaagttagca aaagtttaca agaattaaga
    28321 gcaagacagc taaaaaatgg tcacttgcaa ctggatggca ttagagctct acaagtatcc
    28381 aaactttttg aaggcatgac atctgttcat ttttcaaagg aattagaaga gttagcctat
    28441 catttgcagc atcctgaaac tttttcaata aaaccgttac cagttaaggc tcaaatgcga
    28501 gattatcaac gcaacggtgt tcagtggtta tcaatgctca atcattatgg ctttggtggc
    28561 attttagcag atgacatggg acttggaaaa actctccaga cacttgcttt tttagctagt
    28621 cacctgaaat cagatagtaa agtgctcatt ttatctccat ctagtcttat ctataattgg
    28681 tttgatgaat gtcaaaaatt cacacctcag ctagatgttg tagtttctta cggacttaaa
    28741 caaatcagag atcaaatcat cgaagaaggt catcaaataa ccataaccag ctattcctcc
    28801 tttagacagg attttgagac ctatcaagcg tttcactacg attatcttat cttagatgaa
    28861 gctcaagtga taaaaaatgc gcaaactaag atttcacact gtttacgtgc gtttaataca
    28921 gccaattgtt ttgcgctttc gggcactcct attgaaaata aaatgcttga aatttggtcc
    28981 attttccaaa ttgttttgcc agggttgcta ccgactaaaa aagagttttt aaaattaaca
    29041 gctgagcaag tatcgcgcta tatcaaaccc tttgtgatgc gtcgtaaaaa agaagatgtc
    29101 ctaccagaat tacctgattt aattgaaact aattattcaa acgagatgac agatgaacaa
    29161 aaagctattt acttagcgca gttaaggcag atgaaagatc aaattcgaaa ttctagtgat
    29221 gtggatatta gccgtcaaaa aattgagatt ttatctggta tcactcgatt gaggcaaatc
    29281 tgtgacactc caagtctctt tatggattac caaggcaaaa gtggtaagct agatagtttg
    29341 cgaatcttat tgacacaaat taaagaaaat ggtcatcggg ctttgatttt ttctcaattt
    29401 agagggatgc tggacttggc caagcaagag atgactgctc taggattgac ctcttatcaa
    29461 atgacgggat ctacccctgc caatgaacgt caagaaatga ctagagcctt taataacggt
    29521 tccaaggatg cttttttgat ttccctcaag gcaggtggag ttggaatcaa ccttacggga
    29581 gcagacacag tgattttaat cgatttatgg tggaatcctg ctgttgaaat gcaggcaatc
    29641 agtcgcgcct accgtattgg tcaaaaagaa aacgttgaag tatatcgctt aatcactcga
    29701 gggacgattg aagaaaagat tttagagctt caagaaagta agcgcaattt ggtgactaca
    29761 gttttggatg gcaatgaaag ccgagcaagt atgtccattg aagaaataaa agaaattttg
    29821 gggctaaaca ctcattaatc ttccttgatt ttagtgacat taaaaaccct ttaaagaaga
    29881 tgacaccaaa agcaccttat ataacctcgt taaaacgctt ctttttgaaa tatctttatt
    29941 gatatagcga ttgtcacttg ctagtaatga ttaaaacatt tagaaaaaga caagtcatag
    30001 aatcatcaag gaatgctttg aaaaataaca gtatttaagt tataatagag gatgctacaa
    30061 gaagggagaa tcaaaaaagg atggtaaaaa atcagtttcc tttagttgca gatggcattg
    30121 ctattagtga tccagcaaag caaatggctc tgtatgaaaa tgaagatctc attaccaaca
    30181 tccgtggcta ttaccaggac aaggagtatg atgatattgc tagaaatgag gagtttactg
    30241 ctaaagcaac ttctcggcag gccccttcta gtaagcgctt ttgtagcaat gatgaaaaac
    30301 accattatgt caaagaggcg cgtcaaaaag caaagcaaga tctcaaggaa aaaagacagg
    30361 cttatcttgc caaagaaatg gcctatgttc ctaaacaggt ttctaaaaag caacagcctg
    30421 cggattcttc tccttctcaa aagcaagcaa caacagaaat gagtcgtttt acaaaaaagc
    30481 ttcatcaaga caactatatt ttagctgagt tgccaaaaga atataaagag ccaaaaaatc
    30541 ttcctcaaca aggaactaca aaaaaaaata attacgattt tttaaaatcc agtcaaattt
    30601 acaataataa agaaatgaga caacaacgag aaaaaacaat tgcgcaagag cttaatctta
    30661 gtaggtttga ggatcttcct taataaatct actcagcgta tgcagatgac aaaggagtta
    30721 agatgtcaaa aacgtatcat tttatcggaa ttaaagggtc aggaatgagt gccttggccc
    30781 ttatgttgca tcaaatgggg cataaggtgc aaggtagtga tgttgaaaaa tactatttca
    30841 ctcaaagagg attggaacaa gcgggcatca ctatcttacc ttttagcgag gacaacatta
    30901 cgccagatat ggaacttatc gttgggaatg cctttcgtga aaacaacaaa gaagtggcct
    30961 atgctttgag acaccagatt cctttcaaac gttatcatga ctttttaggt gattttatga
    31021 aatcatttat cagttttgca gtagcaggtg ctcatggtaa aacttctaca acgggtttat
    31081 tgtcacatgt cttgaaaaat atcacagaca catcttattt aattggtgat ggtactgggc
    31141 gtggatctgc taatgcacag tattttgttt ttgaatcaga cgaatacgaa cgccatttta
    31201 tgccttatca cccagaatac tctatcatta ctaatattga ttttgaccat cctgattatt
    31261 tcacaggaat tgctgatgtg cgaaacgctt tcaacgatta tgctaagcag gtcaagaaag
    31321 ctttgtttgt ttatggtgaa gatgacgaac taaaaaagat cgaagcacct gcacctattt
    31381 actattatgg ttttgaagag ggcaatgatt ttatcgctta cgacattacg cgtactacga
    31441 acggatcgga ctttaaggta aaacaccaag gagaggtcat tggtcagttt cacgtacctg
    31501 cttatggaaa acataacatt ttaaacgcta cagcagtaat tgcaaacttg tttgtagccg
    31561 gcattgatat ggctctagtg gcagaccatc ttaaaacttt ttcaggtgtg aaacgtcgtt
    31621 ttacagagaa aattatcaat gacactatta ttattgatga ctttgctcat catccaaccg
    31681 aaattgtggc aacaattgat gcggctagac aaaaataccc aagtaaagaa attgtagcaa
    31741 tatttcagcc acatactttt actcgcacta ttgccttatt agaggatttt gcttgtgctt
    31801 taaatgaagc tgacagtgtt tatttagccc agatttatgg ttctgcacgt gaagtagata
    31861 aaggtgaagt taaggttgaa gatttggctg ctaagattat caaaccatca caagtagtaa
    31921 cggtggaaaa tgtctctcct cttcttgatc acgataatgc tgtttatgtt tttatgggag
    31981 ctggagatat tcagctatat gaacattctt ttgaggaatt acttgcaaat ttaactaaaa
    32041 ataaccaata acatgtcctg ccttaggcag gttttctcat tctaaaggag tttgatatgt
    32101 tgattagaca ggttcaagga tccgatttgg aagttattgc taccattgaa agtgacaatt
    32161 tttcaccaca agaagcaacg acaagagcag ttcttgaaga gcgcatacgg ctgataccag
    32221 atactttttt agtggcactt atcgatcagg aaattgttgg ctatatcgaa ggtccagttg
    32281 tcactactcc tattttggag gattctttgt tccacggggt gactaaaaat cctaaaactg
    32341 gaggctatat tgctattact agtttgtcca tagctaaaca ttttcagcaa caaggggttg
    32401 ggacagcttt gttggcggca ctaaaagatt tagtagtagc gcagcaaaga acaggtctta
    32461 ttttgacttg tcatgattac ttgatttcct attatgaaat gaatgggttt attaaccaag
    32521 gaatttcaga gtctcaacat ggtggaaccc tttggtacca aatgatttgg aaactttaga
    32581 atcacagctg attcaactgt tggtttgtta aaaataagta acaaatgcat catttaattg
    32641 caattaggat acttttaagt tataatggcg gttgattata tttaggagga ttggctttga
    32701 ccgattttaa ggataaagac caacaagatc agcagcgaag ctttaaagag cagattcttg
    32761 ctgagttgga aaaagcaaat caaatcagaa aagaaaaaga ggaagaactt tttcaaaaag
    32821 agttggaagc taaagaagca gctaagagaa cggcccagct atatgctgaa tataaaaggc
    32881 aagatgcttt tcaaaaagag tctatagcac ataacaataa gacagctaaa cactttcaag
    32941 ctataaaagg tgcggtaatg acttcagaag cgcttaaacc gactttactt tctgaaaaag
    33001 aaaactcatc tttaaaaacg acaaataaga gagtcgtgca ggcaaatgag cttcaagaga
    33061 ctgcctctaa agaatctcaa gtaccgttaa ctattgagaa aggtcattca gtgagacgaa
    33121 aattaagcaa acgccaacag actgagcgag ctgctaaaaa gatttcaacc gttttgatta
    33181 gttctattat tataaccctt ttggctgtta ctctagcagg agcaggctat gtttatagcg
    33241 ctttaaatcc tgttgataaa aatagtgatg cctttgttca agttgagata ccatctgggt
    33301 caggcaataa attgattggt caaattcttc aaaaaaaagg tttaatcaag aatagcactg
    33361 tttttagttt ttatacaaaa tttaaaaact ttacaaattt tcagagcggg tattacaatc
    33421 tgcaaaaaag tatgagtcta gaagaaattg ctagtgcttt acaagaaggt ggtacagcag
    33481 aacctaccaa gccatctctt gggaagatct tgattccaga aggatacacg attaaacaaa
    33541 tagctaaagc tgttgagcat aatagcaagg gaaagaccaa aaaagctaaa acacctttta
    33601 acgagaagga ttttttggat ttagtcacag atgaggcttt tattcaagat atggtaaaaa
    33661 gatatccaaa attattagca actatcccaa ctaaagaaaa agctatttac cgtttggaag
    33721 gttacctttt cccagcaacc tataactatt acaaagaaac taccatgaga gaacttgtag
    33781 aggacatgct ggcagctatg gatgctactt tggtacccta ttatgataaa attgctgcta
    33841 gtggtaagac agtcaacgag gtattgacct tggcctcttt ggttgaaaaa gaaggttcaa
    33901 cagacgatga cagacgtcaa attgcaagtg tcttttataa ccgccttaat agcggaatgg
    33961 cactacaatc taatatagct attttgtatg cgatggggaa acttggtgag aaaacaacct
    34021 tggctgagga tgctactatt gacaccacca ttaattctcc ttataatatt tataccaata
    34081 caggtctgat gcctggtcca gttgctagct cgggggtttc tgcaattgaa gcaaccctaa
    34141 atccagcctc aacggattat ttatactttg tggccaatgt ccatactggt gaagtttact
    34201 atgcaaaaac atttgaagaa cactctgcaa atgttgaaaa atatgtgaat agtcaaattc
    34261 agtaaacaca aacatggtgc ttaagcacca tgtttgtgtt tctgattcgt tcaaaaaaga
    34321 aaagagagaa aacaattatg gcagaaaaaa cgtatccgat gaccctaacg gaaaaagaac
    34381 aacttgaaaa agaacttgaa gaattaaaac ttgtgcgtcg tccagaaata gtggagcgta
    34441 ttaaaattgc acgttcgtat ggagatcttt cagagaactc tgaatacgat gccgcaaaag
    34501 atgagcaagc ttttgttgaa ggtcaaattt caacgcttga aactaagatt cgctatgctg
    34561 aaatcattga cagtgatgct gttgcaaaag atgaagtcgc tatcggaaaa acagttatcg
    34621 ttcaagaagt tggaacaaca gataaagata cctatcatat tgtaggtgct gctggagcag
    34681 atatcttctc aggaaaaatt tcaaatgaaa gcccgattgc tcaagctttg attggtaaaa
    34741 aaacaggtga caaggttaga attgaatcac cagcagctac ttatgatgtt gaaatcatca
    34801 gcgttgaaaa gacaaattaa tcagatgaag ccattatttg cctaaccact aagtgttttg
    34861 gttgctaatg gcttttctag tatcttcaaa tgaggttgac tgttaggaag gtcaagtatt
    34921 aatcgcattg attatgagcc aagaggacta tagatcaaag atcgttttcg atggttattt
    34981 aatgccaaaa gaaaagacca gcaccttaat gtactgaccc caaaaagttg gacactatat
    35041 tttaaggaag tgtatgatct aaggaaactg acactaatga ttgaccgttt tgcaagactt
    35101 tattaatgat ttcttgcttt attttaaatg aataagtctg atacgtttcc ttccttaaca
    35161 ctatcgactc catactgacc catcagtcaa acggtatatc tcaaacgact acggtttact
    35221 ccaaattgat tggctagttg aggccaagaa acacctgatt ttttttaatg ctaaatttct
    35281 agcttatctt catagcttaa tttcatacaa aaacacccca atcgttagat ttttttgata
    35341 tgtccccttt cactagatga gtccagtaaa agggggcata tcgttttttg tctaactttt
    35401 ggggtgcagt tcataattgt gctaggtttt ttgtctttct taacgctttc gctgttttcc
    35461 agcattacga ttggatttta tttttttagg caagttagcc tgttccatgt tttgtgaagg
    35521 cgtaacgtcc ttacgagaag aagttgattg gtatgcttta ggcgggtttt tagcgtattc
    35581 ttctttaatt tgcttatgca atcgaggttt taagaggtag gctgtgatta actgttgaat
    35641 aatactaaag aaaccaccaa ctagccagta aagaccaaca ccagcaggga gtgagaagga
    35701 catgaagatc atcatgatag gcatggtgta catcatcgtc ttcatttgct cacgttgttc
    35761 ttctgaaacg gccatcattg ataaccatga ttggaagaag taaagagcag cgataattgc
    35821 tgttaacact aaactacggc taccaagatc aatacccata aaggtgcttg ttgatactcc
    35881 tttagtgtat tgagcggcaa aatacatggc agaaaagaat ggcatctgga tgagaagagg
    35941 tagacatcca atacctccaa gaggattaat cccatgagca cgctgagcag ccattaattc
    36001 tgtttgggca gccatttttt cttcctgact acttgcctgt ttgatacgtt tgttgattgg
    36061 ttcaaaaaca ggtttcaaga aggccatttt ctcagattga taacttgctt tccaagattg
    36121 atatagacct agtggtaaga taagtgttct aacaataatg gttacgatga tgatagccag
    36181 tccataacct agtccagcat tgtttgcaaa gtaatcgata aagtatgaca tgggttttcc
    36241 aagaaattcc caaatcatac ctttgggatt tccgtgagcg tctcttccca cacagcctgt
    36301 caaggtgaat agaattgaca gtgctagtcc tgaaaagagg atgcgattta atgttagttt
    36361 caatgtgttt atcctttaat tttaatatac ttatctattt tacagttttt ttcagaaatt
    36421 cacaatagtt ctgaaggccg atttttactt gcctatttga aagtcctgaa agtcttcaaa
    36481 attagccatg gtgacatcca cataagtgac ttttgcccat ttggatggtc ctttacgaac
    36541 ttcttgaata aatgtggcta ttttatctga atcttttgat tgggccagga tttcaacggt
    36601 cccatcgttg ttattccaga cacgaccata aatatctcct atatctagag ctaaagtatg
    36661 ggtagcgtat cgaaaaccaa caccttgtac acgtccagaa acaattaaac gtactttttg
    36721 cataagaagg gcctccttgc ttttattata gcacatactt agcaggaaat ctctttagct
    36781 aattgtctac ttcctgtcac ttttactaaa gacaagaata caaaaatgag atagttagta
    36841 gtactaacag taaaagaggt ttgtctattt taaaaatagt atcaaaaaaa ggtcttttag
    36901 gtttaaaaca ttgaactgcc cccaaattga ccatctaaga agttgatgct ttcaaatgct
    36961 gtcgcgtatg gtataatagg cgcatggtta ttacatcaaa aacaaatcaa ctaattaagc
    37021 aaacaaaaaa attattgcaa aaaaagcatc gaaaacagtc ctatttgatt gagggctggc
    37081 acctttttga agaagcccaa aaatcaggac aagtttttcg ccacatcttt gttttagagg
    37141 aaatggtgga gcgtctagca ggtgagcaag aactcgttat tgttagccca caagtgctca
    37201 aggagttgac cgactctcct agtccacaag gcattgttgc tgaggtggag atacctaagt
    37261 tagcctttcc atcagattac aaagggaaat atttggtttt agaggacgtc caagacccag
    37321 gaaatcttgg gaccatcatt cgtacagcag acgctgcacg gtttgatggg gtctttcttt
    37381 ctgaaaaatc agcagatatt tacaaccaaa aaaccctacg ttccatgcaa ggtagccatt
    37441 ttcatttacc aatttggcga acagatgtct atcagctttg tcgagagctc caagagtata
    37501 aaactcccat cctagcaaca actctgtcaa agaaatctgt tgactataaa agcctcacac
    37561 atcatgaaag gttggctttg gtgttgggaa atgaaggcca gggcattagt gctgaaatgg
    37621 cagccctagc agaccaactg gttcatatta caatgcctgg tcaggcggaa agtttgaatg
    37681 ttgccgtagc agcaggaatc ctcattttca gcttgattta agctaatatg atataataac
    37741 caagtgaggt aattatgtta tgcattatac agaagataaa gaatatatgg aacacgtcgg
    37801 tcatttgatt gctcatcctc gctttcaaaa attgagtcat attgttcagc accaacattc
    37861 aacgcgtctt gaacattcta tcaatgtttc ttattccagt tataaattag ccaagcgatt
    37921 tggttgggat gctaaaagta cagccagagg gggcttactt catgatttct tttattatga
    37981 ttggcgcgtg accaagttta ataagggtca tgcctgggtt catcctcgta ttgctgtacg
    38041 aaatgcgaaa aagttaacag aactcaataa aaaagaagag gatatcattc taaaacacat
    38101 gtggggagcg accattgctt ttccgcgtta caaggaaagt tatattgtga caatggtaga
    38161 taaatactgg gctgtcaagg aagcagtgac gcctttgaga caaaaatggt ctaatcgacg
    38221 gtttcttcgc cgcaagaccc tccaaagtca taatcgttaa gtaaaggagt tattatgaac
    38281 gatcacgtta tttatacaca atcagatgtg ggattaaatc agttttttgc taaaatttat
    38341 agtctagtgg gaatgggagt gggtttgtct gcttttgttt cttatttgat gctttatcca
    38401 tttagagaaa atttaatctc tattcttgtt aatcagccga tgatttacta tggtgctgcg
    38461 attattgaac ttattttagt ttttgtagcc agtggtgcag cacgaaaaaa cacaccagct
    38521 gcattgccca tttttcttat ctattctgcg ctaaatggct ttaccctaag ctttattatt
    38581 gtggcatacg ctcaaacgac agtttttcaa gcatttcttt cttcagcagc tgtgtttttt
    38641 gccatgtcaa tcattggtgt caagactaaa cgggatatgt caggtcttag aaaggctatg
    38701 tttgctgctt tgattggtgt tgttgtggct agtctgatta atctttttat tggtagtggg
    38761 atgatgagtt atgtcattag tgtgatttcc gtgctaattt tctcaggtct catcgcatca
    38821 gataatcaaa tgattaagcg cgtttatcaa gcaacaaatg gccaggttgg tgatggctgg
    38881 gctgttgcta tggccttaag cttgtattta gattttatta acttatttat cagccttctt
    38941 cgtatttttg gaagaaatga ttaacattaa aaagtgagta taactactca ctttttaatg
    39001 ttaacaggat aagtaaactg taaggaagaa attcgagata gatataagat gaggctgcta
    39061 aaagacctag tgttaatttg taaactcttt ctttttttgg tatactgtta aggattaaat
    39121 acgaggagaa tatagataga tatgtcaaca gctatttgga ttttattact tattgttgcc
    39181 cttggggtag gtgtttttgg tgggattttt attgcccgta aacaaattga aaaagaaatt
    39241 ggtgaacacc cacgtttaac accagaagct atccgtgaaa tgatgagcca gatggggcaa
    39301 aaaccaagtg aagcaaaaat ccaacaaact tatcgtaata tcatcaaaca atcaaaagca
    39361 gccgtatcca aaggcaaaaa ataaaagcta attgttatag gggaaacctt tgtgatagtt
    39421 agaagtgaac agtctttgat ctcaatgttc agtagcactt gtcttatcag ttagatttgt
    39481 caactgttca gggtttaaaa agaaactcag ttggctattt ccaactgagt ttttcatatc
    39541 gtcagtaagg aagtaaacat aatggataca agaccaattg ggtttttaga ttctggtgtg
    39601 ggaggtctga ccgtcgtttg tgaattgatt cgtcagctcc ctcatgagaa gattgtatat
    39661 attggtgatt cagcaagagc cccctatggt cctagaccca aaaaacaaat taaggagtat
    39721 acttgggagc tagtcaattt tttgctgact caaaatgtta aaatgattgt ttttgcatgc
    39781 aataccgcaa cagcggtggc ttgggaagaa gtaaaagcag ctttagatat tcctgtttta
    39841 ggggttgtct taccgggggc aagcgcagct attaaatcaa cgacaaaagg ccaggttggg
    39901 gtcatcggaa ccccaatgac agtggcttca gacatttatc gcaaaaaaat ccagctatta
    39961 gcaccatcta ttcaagtaag gagtcttgct tgcccgaagt ttgtaccgat tgtggaatca
    40021 aatgagatgt gttcgagtat agctaaaaaa atagtttatg acagtctatc accattagtc
    40081 ggtaaaatag atacccttgt actaggatgt actcactatc ccttgttacg accaattatc
    40141 caaaatgtta tgggaccatc tgttaagctg attgacagtg gagcagaatg cgtccgagat
    40201 atctctgtct tattaaacta ttttgacatt aacggtaatt atcatcaaaa agctgtcgaa
    40261 caccgctttt ttacaacagc aaatcctgag atttttcaag aaattgcctc gatttggctg
    40321 aaacaaaaaa taaatgtgga gcatgtcacc ttatgagtga aaaaatttac gaatacaaag
    40381 atgaaaataa ctggtttatc ggaaagatga ctggtcataa tttaatatcg ggctggggag
    40441 tcaaacacac gacaatcaaa aaaatagatg accttttaga cggtattgcc gcaacgttag
    40501 attgggaaaa tcctaaaggt tacgatgttt cggtggtgcg ttatcagtct cctttatctc
    40561 tcatcacctt tattatcgac atgataaatc aagagaccca gcgtaaggtt aaggtaactc
    40621 cccatgcagg cacgatttta ttaatggaaa atgcgaaact gcttgcagtt tatctcccag
    40681 aaggtggagt ttcaacggct acattttttg cgactagtga acagagattt ggggatactg
    40741 ttttaatcgc tacacgaaac gagggaaaaa ccaaagagtt ccgcaatctg tttggccagc
    40801 taggttatcg tgtggaaaat ctcaatgatt atccagaatt gccagaagta gcagaaactg
    40861 gtactacttt tgaagaaaat gctcgcttga aagcagaaac gatttcacgc ctcacaggaa
    40921 aaatggtatt agcagacgat tcaggactaa aagttgatgc cttgggtggt ttacctgggg
    40981 tttggtcagc tcgtttctca ggaccagatg ccacagatgc caagaataat accaaactct
    41041 tacacgaatt agctatggtg tttgaccaaa agaagcgctc agctcaattt catacgactt
    41101 tggtagtggc tgctcccaat aaagatagtt tggttgtgga agctgagtgg ccaggctata
    41161 ttgctacgca gcctaaggga gaaaatggtt ttgggtatga ccctgtcttt atcgtcggag
    41221 agactgggcg tcatgctgca gaattagagg ctgaccaaaa gaatcagttg tcgcatagag
    41281 gtcaagcagt tcgaaaatta atggaggtct ttccagcatg gcaagcgaaa caatcatagt
    41341 aatgagtgac tctcatggtg accgagatat cgttcaagcc attaaagaca agtatcttgg
    41401 tcaagttgat gctattttcc ataatgggga ttctgaatta aacagctcag atcctatttg
    41461 ggctggtatt tatgtcgttg gcggtaattg tgactatgat acaggttacc ctgatcgttt
    41521 agtaactcaa ttaggcacag ttacgattgc ccagacacat ggtcacttgt accatattaa
    41581 tttcacttgg gataaactgg actactttgc tcaagaagta gcagcagata tttgtctata
    41641 tggacaccta caccgtccag ctgcttggca agttgggcaa accctcttta tgaatcccgg
    41701 atcagtaaca caacctcgcg gagaaattaa cgagaaatta tatgctcgtg ttgaactaac
    41761 tgatactcaa attaaagttg attactttac aagagatcat aaactttacc catcactgtc
    41821 taaggaattt aaacgatgat cgcaaaagaa tttgaaacgt ttttaatgag tcatttagat
    41881 aattatctta tcccggaaca agacttggct atttttatcg acacacataa tgcagaccat
    41941 gtgatgttac tattggtgag taatggtttt tctagagttc ctgttatcac acgggagaaa
    42001 aaatatgtgg gaaccattag catctcagat attatgatgt accaatctaa aaggcagctg
    42061 acagattggg aaatgagtca aacagatatt ggcgagatgg ttaataccaa aattgaaacc
    42121 attagcatta cttctagcct aacagaaatt atgcacaagt taattgattt cccattctta
    42181 ccggttgtag atagagcgaa tcgctttgtt gggattatta cgcgaaaatc tatattaaag
    42241 gctgtcaaca gtcttttaca tgattttaca gatgattaca cgattataaa aaaatgaaga
    42301 gttatattga accttttatt gctagcaagg ctttatctca aaatagtcaa aaagcttatc
    42361 gatacgattt gcaacagttt tgtcaactgg ttggtgaacg tgtcaatcaa gacaaactat
    42421 tactttatca aaatagcata gctaacctaa gtttatctgc aaaaaaacgc aaattatcaa
    42481 cagctaatca attcttatat tacttgtatc aaataaagta tttaaatagc tattttcgat
    42541 taacagatac catgaaagtg atgcggactg agaagcagca agctgctatt attaatactg
    42601 atattttcta tcaaaaaacc ccttttgtgt gggggcaatt aatcagctta ttaatattgg
    42661 agctgggttt aactccgagt gaagtagctg gtattgaagt agctaacttg gatttaaatt
    42721 ttcaaatgtt gacgctaaag actaaaaaag gtgtgcgtgt attacctttg tcgcaaatac
    42781 taatcccttt tttagaacaa caactcgttg gcaaagaagt ctatcttttt gaacatcgag
    42841 gcatcccttt ttcaagacaa tggtttttta atcacctaaa aaccttcgtt cgaagtattg
    42901 gttatgaagg attaactgct caaaaattac gagagcaatt tattttgaaa gaaaaactag
    42961 ctggtaaatc gataatagaa cttagcgata ttcttgggct gaaaagccct gtgaccttag
    43021 aaaaatacta caaatcataa tggatataaa acttaaagat tttgaaggtc ctcttgattt
    43081 actcttgcac ttggtatcac agtacaaagt tgacatctac gaggttccta ttgttgaggt
    43141 tattgagcag taccttaatt atattgaaac cttacaggta atgaaacttg aagtggctgg
    43201 tgactacatg ctgatggcaa gtcagctcat gttaatcaaa agtagaaggc tattaccaaa
    43261 ggtggtagaa cacatcgaag aagaagattt agaacaagat ctgttagaaa agatcgaaga
    43321 atatagtcgc tttaaagcag ttagtcaagc gttagcgaag caacatgacc aaagggcaaa
    43381 atggtattca aaacctaaac aagaattaat ttttgaagat gctatcttac aagaagataa
    43441 aacggtgatg gatctatttc tagctttttc aaacataatg gcagctaaaa gagcagtttt
    43501 aaaaaccaac catacagtca tcgagcctga tgattataag attgaagaca tgatggcttc
    43561 tattaaacag cggctggaaa aagaaaacgt tattagctta tcagcgattt ttgaggaatg
    43621 ccaaacatta aatgaagtta tcagtatatt tttagctagt ctagaattga ttaagcttca
    43681 cgtggtattt gtagagcagc tctctaattt tggggctatc atactacgaa aggagaagaa
    43741 atgacgtatt tgtcacagat agaagcgctg ctatttgttg caggtgaaga aggattaagt
    43801 ttgcgacatc tagcgtctat gttatcatta acgccaacag ctcttcaaca gcaattagaa
    43861 aaactctctc aaaaatatga aaaagatcaa cattctagtc tttgcttgat agaaacagct
    43921 aatacctaca ggctagtaac taaagaaggt tttgcagaac tcttgcgtgc ttatgccaaa
    43981 acaccaatga accaaagttt atctcgtgcg agtttagagg tcttgtctat tgttgcatac
    44041 aaacaaccta ttacacgaat agaaattgat gacattcgag gggtaaactc cagtggagct
    44101 ttgagtaaat tattggcatt tgatctcatt agagaagctg gcaaaaaaga tgtggttggg
    44161 cgtcctcatt tgtatgcgac aacagattat tttctggact atatgggaat taatcattta
    44221 gacgaattga ttgaagtatc tgccgttgaa ccggcagatg aagagattgc tctttttagg
    44281 acacaagact gagttttgct tgtcatcaaa tagcaaatga cgtttacaaa aagatttgtt
    44341 ttaaggcgtt ttagttgaaa aaagccttaa actagggaca acaaaaagtt gctcaaaaga
    44401 aagaagaata taatgcgaat taacaaatac attgcccatg cgggtattgc cagtcgtcgt
    44461 aaggctgaag aattgattaa gcaaggctta gtaaccttaa atggtcaggt tattacagat
    44521 ttagcaacca ctgtaaaatc gggagacgtg gttgaaatag aaggaagtcc tatttacaac
    44581 gaggaaaagg tttactattt gcttaataaa cctcgtggcg ctatctcaag tgtgtcagat
    44641 gacaaaggcc gtaaaacggt actgggttta ctacctcagg ttaaagaacg catataccct
    44701 gttggacgat tggattggga cacatcaggg gtccttattt taacgaatga tggtgatttt
    44761 acagatacta tgattcatcc tagaaatgaa atagacaagg tttatctggc gcgtgtcaaa
    44821 ggaattgcaa cgaaagaaaa tcttcgtccc ttaactcgag gaattgttat tgatggtaaa
    44881 aagaccaaac cagctcgcta caatattgtt cgtgtagaag ctgataagaa tcgatcgatc
    44941 gtagaattga ctatccatga agggcgaaac catcaggtta aaaaaatgtt tgagtctgtg
    45001 gggcttttgg ttgataaatt atctcgtaca cgttttggga ccgtcgactt aaagggacta
    45061 agaccaggag aagcaagacg cttaaataaa aaagaaataa gtcaactgca taacttagct
    45121 aatacgaaaa aatgatgaaa aaactattaa tagtatctgt taaagcttat caaaaataca
    45181 tttctccttt atctcctcct agttgtcgct acaagccaac ctgttcagct tatatgttaa
    45241 ctgctattga aaaacatggt actaagggaa tattaatggg gatagcaaga atattaagat
    45301 gtcacccttt tgttgctggt ggtgtcgatc ctgttccgga agattttagc ctaatgagaa
    45361 ataaaaacac gtctaaaaac gctgaaaagg catgacttta tcaaaaaatg gcttgacatt
    45421 gatagctgaa gtgttataat ggaaaacaag cattcgttgg tttaaatcaa acctgttatg
    45481 atttaagtta gcgagtcacc atcaaccaca ttgtttgctg agcatgactc cgagcagtgt
    45541 ggttttttaa attaaaaaga gtaaatgaga ttatgacgac aaaagaactt atcaacaaaa
    45601 acgacaaggt aaaaaaggct cgcaatcata ttgtcctgtt tcaaccccaa attccacaaa
    45661 atactggtaa tgttgctaga acatgtgctg caactaatgc acctttacac attattaaac
    45721 ccatgggatt tcctattgat gaccgcaaaa tgaagcgtgc cggcttagat tactgggaca
    45781 agttagaact gcatttttat gatcatttag aacagtttat caatcaatgt cacggacagc
    45841 ttcacctgat tagcaagttt gcagttaata attattctca agctacttat gctgatggcg
    45901 attcccatta tttcttgttt ggacgagaag atacaggcct gccagaagat tttatgcgag
    45961 aacatgctga aaaagcactt cgtattccga tgaatgatga gcatgtacgg agtttaaatg
    46021 tctcaaatac ggtttgtatg gtgatttatg aagcccttag acaacagggc tttcaagggt
    46081 tagagttaaa gcatacttac gaacacgata aactaaaata atggactttt taaaagcgtc
    46141 agtttttggc aacatgcgtt gtcagtagct gacgctttta aaaatttagt caaagctatt
    46201 gctatctagg tttaaatctg ctatgctaga agtgtcttca gggcagggtg tgattcccga
    46261 ccggcggtga ctagtaacta gaagtccgcg agcgcaagct gatgtggtgt aactccacaa
    46321 ccgacagtat agtctggatg agagaagacc gggctttttg tgtaggctta ttttagctac
    46381 acaataacga cggaacttct ttcaatttga aaaaattgga ggaatttttt aatgtcaaaa
    46441 acacataaaa tgattatgat tggtatactt tctgcgatat catttctatt gatgctagtt
    46501 agctttgcca ttattccagg cgcagctttt ttaaaaattg aatttagtat tattcctgtc
    46561 ctatttggtt taatgattat ggacttaaag agtgcttact tgattttgtt attgaggtcc
    46621 ttattgaaac tctttttgaa caatcgtggg gttaatgatt ttattggtct cccaatgaat
    46681 attatcgcta tcgctctatt tgtgacggct tttgccttag tttggaaccg tcaaaaaacg
    46741 cttagtcaat atgtatttgc tagcttacta ggcacagggt tattaacatt tggcatggtt
    46801 gttctcaatt atacttttgc cattccttta tatgctatat ttgcaaatat tgatatcaga
    46861 gcttatattg gtgtcactaa gtatatgatg actatggtta ttccgtttaa tcttgttgaa
    46921 gggttgatat ttgcaattac cttttatttt gtgtatattg caagtaaacc aattttagaa
    46981 agatacttac actaatatga tgacaaacaa acaaactcac tttttaatag cttcttttgc
    47041 attactaatc tttgttataa taggctatac ggtcaaattt tttcctgaac gtttggcact
    47101 tctagataat actattcaag cagagattag aggcaacctt cctatagtgc tgacgcaatt
    47161 ctttaggggt gttactgtat ttggaaatgt catgacacaa gttttgttag ttattgtgtc
    47221 ggtcctagtt ttattcttta tgaagtggaa aattgaagcc ttgtttatct tatcaaatgg
    47281 tgccattgca gcatttttga ttacgactct caagctcttt taccaaagac caagacctgc
    47341 tattgagcat ttggtttatg ctggtggcta ttcgtttccc agtggccatg cgatgggtag
    47401 catgctgatt tttggtagcc tattgattat ttgttatcaa aggctacatt caaaactatt
    47461 acaatttgtg actagcatga tctttataat actaatttta gtaattgggt tatctcgtat
    47521 ttatctaggg gtacactacc caagtgatat tttagcaggc tttgtattag gatttgggat
    47581 tttgcagttt atttatcctt tttataagca aaaacgattt gaatggcgat ttcttttgaa
    47641 acaagactaa tttttcttga gaagacatag ggcttattta aatcatttag aataacattg
    47701 gcaagcatca ccccttgatt gccagtgtta ttttagtttt agttagatga tgtgagctga
    47761 tgattagtaa atacgtttag ataaaaaatg attaaagtgc tatgtaacgt cagaaaagac
    47821 gtgatttttg ttgatctgta atcattaagt aagctgatgt agaagtagtg aattctaatg
    47881 actgagctat cttttgcata gatgactatc ttgctagtaa tgatttgtgc tacaatagaa
    47941 acatgaaaaa aagatatcag acattaaacg agcattaccg tcaactattt ggcgcaaaaa
    48001 tgtttaaagt tccgattgat gccggctttg attgtcccaa tcgtgatgga acggtagctc
    48061 atggaggatg tactttttgc acagtatcag gttctggaga tgctattgta gcaccagatg
    48121 ctccaattaa agagcaattt tataaagaaa ttgattttat gcaccgtaaa tggcctgatg
    48181 tcaatcgcta tttggtttat tttcaaaact ttaccaatac tcatgataca gttgatgtga
    48241 ttcgggaccg ttacgaacaa gctattaacg aacctggagt tgttggtatt aatattggca
    48301 cacggcctga ctgtctacca gatgatacca ttgcttactt agcagaatta tcagaacgca
    48361 tgcatgtgac agtggagcta ggcttacaga caacttatga agaaacttct aggctaatta
    48421 acagagcaca ttcttatgat ttgtataaag aaacggtgag gcgactaagg cattacccca
    48481 acattaatat tgtctcgcac ttgattaatg gattgccaaa agaaacccat gacatgatgc
    48541 ttgaaaatgt gagacgctgt gtaacagaca atgacattca aggaattaaa ttgcatttac
    48601 tgcatttgat gaccaatact agaatgcaaa gagattacca tgaaggacgc ttaaagttgt
    48661 tgagtcaaaa ggactatgtt tcgattattt gtgaccagct agagattatc cctaagcata
    48721 ttgtgattca ccgtattaca ggagatgccc cacgagatat gttgattgga cccatgtgga
    48781 gtctaaataa gtgggaagta ttgaatgcca ttgataaaga aatggaaaga cgaggaagct
    48841 ttcagggctg taaagttgac taatttgtct cattttgacg gatttggata ggagaaaagt
    48901 gatgctaaaa cgccccattc atctctcgca tgatttttta gcggaggttg tggataagtc
    48961 tagtgtggtt gttgatgcca cgatgggtaa tggaaatgat actgcctttt tggcacaatt
    49021 agctaaaaag gtttatgctt ttgacgtgca agaacaagct attagaaaaa caagtgagcg
    49081 gttagcgcag ctaggattat cgaacgctga gctgatttta gcgggtcatg aagcagttga
    49141 tcagtatgtg acggagccgg tgagtgcagc gatttttaac cttggttatt tgcccagcgc
    49201 agataaatct attattacct taccaaatac cacactccaa gctttatcaa aactactaac
    49261 gttattaatg gtaggtgggc gtattgctat tatggtctat tatgggcatg atggaggcag
    49321 tttggaaaaa gatgctttat tagattttgt caagcaatta gaccaaagaa aggtttctgc
    49381 aatgctttat cagcctctta atcaggtgaa taccccacct tttttaatca tgttggagaa
    49441 gttagcagac gtttatccct tatccctgtg tcaagtctac tagaagttct gcgattattt
    49501 cggtggaaaa agaagaaatc ccataggctt tggctataaa tgtgatataa tgaagtcact
    49561 atattatttt tttaggagtt acattaacat ggaagaccct gtgagtcagc ccttagtgat
    49621 tcaattttta ttgttagttg ttttaacctt gttaaatgct tttttttcag ccagtgaaat
    49681 ggccttagtt tctctcaatc gttctcgggt ggaacaaaaa gcagcagacg gtgataaaaa
    49741 atacgctcgt ttgttgcggg ttttagagga acctaatcat tttttatcaa cgattcaagt
    49801 tgggattacc tttattagtt tactatcagg agcaagttta tcagcttctt tgggtaaggt
    49861 gatctcaggt tggctaggta attcagcgac tgcaaggaca gctggtacta tcatctcctt
    49921 ggttttcttg acttatgtct ctattgtttt aggagaattg tatccaaaac ggattgccat
    49981 gaacctcaaa gacaagttgg cgatcgtttc agcccctatt atcattgggt tggggagact
    50041 ggttagtcct tttgtgtggc tcttatctgc ttctactaat ttgctgagcc gacttacccc
    50101 aatgaccttt gatgatgcag atgagcaaat gacacgtgat gaaatcgagt atatgttatc
    50161 aaaaagtgag gcgacccttg atgctgaaga aattgagatg ttgcaaggag ttttctcact
    50221 tgatgaaatg atggcgcgtg aagtcatggt cccaaggacc gatgctttca tgattgacat
    50281 taacgatgat ccgcttgaaa atattcagga aatcttaaaa caaagttttt cacgcattcc
    50341 tgtttatgat gtggataaag ataaaattat cggtctcatc cacactaagc gtctcttgga
    50401 gtcaggtttc cgccagggat ttgatcagat taacatgcga aaaatgttac aagaacctct
    50461 ttttgttccc gaaaccattt ttgtagatga tctcttacgc cagctgcgca atacccaaaa
    50521 tcagatggct attttgctag atgaatatgg tggtgtggca ggacttgtga ctttggaaga
    50581 cttgcttgaa gaaatcgtcg gtgaaatcga tgatgaaacc gataaagcag aacaatttgt
    50641 tcatgagatt ggagacaata cctatattgt tgttggtacc atgactttaa atgagtttaa
    50701 tgactatttt gataccgaac tagaatcaga tgatgtagat accattgctg gtttttattt
    50761 gacaggtatc ggaaccattc caagccagga gcaaaaagaa gcctacgaaa tagataacaa
    50821 agacaaacat ttagttctaa tcaacgataa agtcaaagat ggccgtatta cgaaattaaa
    50881 attaatcctg tctaatatag aacagattat tgaggaagac taggctccat gcctagtctt
    50941 tttgatgaaa agtgttataa tgaaaatgta aaaacgttta caagtaatga aggagatgca
    51001 atgactgaga aagattatgg acaagtaaca gggatggtgc attcgacaga aagttttggt
    51061 tctgtagatg gtccaggcat tcgttttatc attttcttgc aaggctgtaa attacgttgc
    51121 caatattgcc ataatccgga tacttgggag atggaaacca acaattcaaa aatcagaaca
    51181 gtcaatgatg tcttgaaaga agcccttcag tacaaacatt tctggggaaa aaaaggagga
    51241 attaccgtat ctggtggtga agctatgctt caaattaatt ttatcactgc cttattcatc
    51301 gaagctaaaa aattaggtat ccataccaca ctagacacct gtggctttgc ctatagaccg
    51361 acacctgaat accatcaggt tcttgataac ttattggcag tgaccgattt gattttattg
    51421 gacttaaaag aaattgatga aaaacaacat aaaattgtca cgcgtcagcc taataaaaac
    51481 atattgcaat ttgctaggta tttatccgac aagcagattc ctgtctggat tcgacatgtc
    51541 ttggttccag gcttgactga tattgatgat catttgacac gattgggtga gtttgtcaaa
    51601 accttgaaaa atgtcgataa atttgaagtt ttgccttacc ataccatggg agaattcaag
    51661 tggcgtgagc taggtattcc ttatcagtta gaaggtgtta aaccaccaac taaggaacgc
    51721 gttcaaaatg ctaaaaatct gatgcagacc gaatcttaca cagaatatat gaatcggatt
    51781 catcagtcat aagagctgtt atagggttga ggtttcctca actttttaaa gtattataag
    51841 cagatctttt gtaatcttcc tttgatttta gggggtaatt ttgctaaaat aaaatgaata
    51901 aacaaaatga ggtagaatga ttatgtcaaa aattttagtt tttggtcatc aaaatcctga
    51961 tacggatgct attgcatcat cttatgcttt tgattactta tcccaaaaag cgtttggttt
    52021 ggatactgaa gtcgtagctt taggaacacc taacgaagaa acagcttttg cccttgatta
    52081 ttttggtgtt gaggcaccac gtgtggtaga gtctgctaaa gcacaagggt ctgaacaagt
    52141 gattttgaca gaccacaatg aattccaaca atccattgca gatatccgtg aggttgaggt
    52201 atatggtgtg gttgatcacc accgtgtggc taattttgaa actgcaaatc ctttatacat
    52261 gcgtgtggaa ccagtaggat cagcctcatc tattgtttac cgtatgttta aagaaaatgg
    52321 cattgaggtg ccaaaagcga ttgcagggat gctcttgtct ggtttgattt cagatacctt
    52381 gttgttgaaa tctccaacaa ctcatgtgtc tgatcacctt gtcgctgaag aattggcaga
    52441 gctagcagaa gtgaacttgg aagactatgg aatggctctt ttaaaagcag gtacaaacct
    52501 tgcaagcaaa tcagaagtag aattgattgg tattgatgcc aaaacctttg aattaaatgg
    52561 caatgctgtg cgcgtggcac aagtgaacac tgttgacatt gcagaagtct tagaacgtca
    52621 agaagctatt gaagcagcca ttaaagatgc catggctgca gaaggttatt cagattttgt
    52681 tttgatgatc acggatattg ttaactcaaa ctctgaaatt ctagctattg gagcaaacat
    52741 ggacaaggtt gaagcagcct ttaacttcac ccttgacaac aatcatgcct tcttagcagg
    52801 tgccgtttct cgtaaaaaac aagtggttcc acaattgaca gaaagttttg gagcttaatg
    52861 aaaagacgct ttaaaaggac ttggtttttt tgaccaagtc cttttttcac tcttctatgc
    52921 tataatagaa ggtatgataa caatatttca ttcagataaa ctcaccagac aacctttctt
    52981 tcaagacctt atcaattatc tcgaccagca tgattacgtt atattacgag agatcaaaaa
    53041 agcctttcct aatgtgacag gtattgacaa ggccatcgaa agctatgttc aagctggcta
    53101 tattcgccgt gaaaataagc gttatggcat caatcttcct ttggtgagtt ctgatcagca
    53161 gctggcctta gacactatgc tttttgtgga cacctgttca gctatgtatg aaaatatttt
    53221 agcggttgtt tttgagactc agctaacaaa ccaaaccaat cacgtggtga tcaaggaaaa
    53281 gaccaacatc acgagagacg atttgaccct ggctaattat ttttaccgtc tcaaaagagg
    53341 tgagaagcca tcagctgagc agatggactt gtatgacctc ttgggggatg tgaatcagga
    53401 atatgccctt aaatatatga caactttttt gcttaaattc acgcgcaaag accttgtgat
    53461 gcaaaaacgt cctgatatat ttgtggaagc tctggttaca cttggttacc taaaacaagt
    53521 ggagcctaca acataccagc tgctaatgac cttggataaa gaaagtttaa cctttatagc
    53581 accatagaaa aaagctagga acaaggactg ttcttagctt tttgagtgct tttattttgt
    53641 ttttgccatt aagtaaagaa aataaggggc tccgataagc gacactaaaa tccctgtctg
    53701 gatattactg ccaaccagat agactcgtcc tactgtatct gcaacaagaa gtaggatcat
    53761 tccgattaaa atgctaatgg gtattgttat tttatgatta ctccctacca agtatgtact
    53821 aaagtgtcca gctattaagc cgataaaact aatattacca accaaaagaa cactcaaagc
    53881 acctaagcca gctgctaaga caagtatcaa acgacgctta cggtttaaag ggagtcctag
    53941 cccaatagca gtattatcag ctaatcccat aatattaagg aaatgggctt gactataagt
    54001 caatagccaa aaacacaata ataaaggagc gatgacactc agagtaggcc agtcgtctcc
    54061 tattaattgg ccgctaagcc aattgatgac caaatcgact ttgtagcgat taatatgacc
    54121 aacaagagca accattagac ttgaaagcat ggtagtaaca gctacaccag taagaattaa
    54181 ccgtgtagga tcaatttgtc cttgttttgt caaagatagc caataaacgc taaaggttgt
    54241 tacaacagca ccaagcatgg caaataaagg caagtaatgg ctgatatgag cttgctcaaa
    54301 gaaagaaaag gagaccacaa tagccaaaga gatacctgct cctatagtaa tacctaatac
    54361 accagagtca gctaagggat ttcgtgttaa acgttgtaat aatagccctg ataaagcaag
    54421 agaaccgcct cctagaaaag cagctagaat tcttggcaga cgaatgttaa taacgatgaa
    54481 agatatggca tggctagatt ttcccaaaaa cacatggaca aggtccaaaa aagatagatg
    54541 agattctcca agggacaaag ctaatcccat aagacttaca agtagcagga tcaggctagt
    54601 atataacctt aaaaggtgtc ggtgagattt caatagcggc ctcctcttct tattaaccat
    54661 aaaaagcatg gaaaaccaat taagctaacc aatgccccaa gaggggtttc ataaggcgga
    54721 ttgagattac gacaagcaat atcaacccat accatgaaac tagcgccaga aactgcacaa
    54781 agcggcaaaa ggtatcggta atgatgaggt gtaaagtgtt tcataagatg aggaatgact
    54841 aagccgataa aagaaatgct tccagcaatg gctacagctg ctgatgataa aataagaacc
    54901 aaaatcataa agactgcact gatcaagttg gtcttttgcc caagagcttt tgcctgagac
    54961 tcacttagac taaggacggt caggtgataa gataatagct gggctaaaca aagactaaga
    55021 ataataagag gagcaatata gccgatcatt tgccaattga ccccgacaag acctcctgct
    55081 tgccagccga taacagcatt tgtcagatga tagtaattgg taataccttg acctaatgct
    55141 gatagcagta tggaaaccat agctcctgct aagacaaggc ggagctgatg gtagcctttg
    55201 ccagattgat aagaaaggcc aaagactaag gttgctgcca ggctagaccc taacaacgaa
    55261 agcagaataa tgagggaata gtgcaagtga ggtacaaacg cataagccag taccaaggct
    55321 agtcctgctc cagcattaat gcctaaaagg ccaggctcag cgataggatt acgtgtgatt
    55381 gcttgcatga tagttccaga aacagctaac gcagagccag ttaaggtagc accaaaaagt
    55441 ctcggtaatc gtatagctag taaaacattg gctttatggc cgttttgctt tccaaataaa
    55501 atagagttaa gatcctgatg tgataaagca acggctccaa agcgcagatg acagtaaata
    55561 gcaacacata agctaaaact aagtagcaca aagacaagcc aaaagatatg tgacttagtg
    55621 attatctgcg ttttttttaa gcaaaaacgc tcgagacaca aaaagggatg cttagttttc
    55681 acttgataag attgcctctc gtaaagtctc taattgatat tctaaagaaa gaggatcagt
    55741 aaagtaaaag acattggcat tgactttgat cacatggtgt tttttcacag ctggaatgga
    55801 ttgccatagc ttgctttcat atagagcaga accagtctta tcatcttctg cagcaacgac
    55861 gacataatca acaatatagt ctggcaagac ttcctgcgac aatgacaggt aaccttgttt
    55921 aaaaacttca gtcttcactt tttcaggagc atcataatgg aaagcttgat ggataacctc
    55981 tccgccacgt ccccagtctt taccaaaaag gtaaacgtct ttttcataaa gccccataat
    56041 agtaaaggtt gctttgtcac ctgtaacggc cttgacttct ttttcataag ctgctgtttt
    56101 agttttccaa tcttttaacc atttcttggc tttgccttct ttgttaaaga tgcggccgaa
    56161 gtcagataac acttgtaaat aatcacgttt gcggtattca atcgaaataa caggcgcaat
    56221 ttctgccaat tgtttaatat tttcttctgt agagccaaca acaatgaggt caggcttaag
    56281 cgttgtaatg gcttctaaat cagttgcagc aacttgcttt gcttttttta cagtctttgc
    56341 taagatgggg tttttcttgt cataagaagt aaccccgact agattcatat ctaatttttt
    56401 gaggtaacca gtgtaagttg aagccagact gactactcgc ttaggctgtt taggaatatc
    56461 tccgtaataa gtcacaccag caatttgagg cataggcgat aaactttttg aggcggtgtt
    56521 agaatgatta gttgcttgat taccacaggc gattaaggta atggttgtca aacagagtgt
    56581 taatagtaga gttaattttt tcatgtatgc taattctcct agaataaagt tattgaagct
    56641 gataagtcag cactatagga cagttgtgga taggatcatc aaccagtacc ggtttgattt
    56701 ggaagatgtc ttgaatgata ggtgaagtca taacatctgc tatagtacca gtataatgga
    56761 tcttgccatg tttcatagca atcagatgat ccgaatagcg ggctgaaaga ttgaggtcgt
    56821 gaagaaccat aacaatagtc ttgccggcat ccttatttag ggatttaacg agctctagga
    56881 tttctagttg atgatttaaa tctaaataag tagttggctc atctaaaaaa atagtatcag
    56941 tgccttgggc taatgccatt gcaagccaaa ccctttgacg ttgcccccca gaaagagcat
    57001 caacaggttg atcagcatag gccatgacat tggtggcttg catagcccaa tgaatggctt
    57061 ttttgtcagc tggactaaga tttccaaagt aagattgatg gggaaaacgt ccgtaagaaa
    57121 ccaattcgta aacagttatg ccgttagttg cttcttgaac ttgaggtaaa agagctagtt
    57181 ttttagcaac ctctttagtt tctaatgtgg caatgttttg cccatttaaa tacacaactc
    57241 cctgttttgg tggtaataat cttgtcagtg cttttaataa actagacttc ccacagccat
    57301 tggcgccaat aatggtcgta attttacctt caggaatata aaacgataat ttatcgatga
    57361 tggtacgctg ttcataggca attgtgaggt cttcagcact aattgttgtc atatggttgc
    57421 ctcctttcta aaaagagtca aagggttgat gaaagtgcac attaaagtat tcatctgccc
    57481 attttaaaat agttgagaag tagcttattt tctcaaaatc ttcactatta tagcatagaa
    57541 aaaaggctta acaaagcctt ttttgatgtg atttttagga tgtattaaaa aagaaatatt
    57601 agtttagaat gattaaaaac aatagcgaga atcattctaa agtaacttca acatactcta
    57661 gaggtagtgt ttggcgattg ctaaatcacc agcataagct acttgttgtc ctttaacaat
    57721 ttgataagca tctgcgcctt tcccagcgat aatcacagca tcttttgctc cttggcaaag
    57781 agacatggct ttttgaatag cttgctcacg gtcactaata atctctaccg ggcgtgcgat
    57841 atggctggca atttcttttg aaatatcttc tggatcctcg aaattagggt catcagcagt
    57901 gagaatgacg gtgaggtttg gatgctgatg aatcacccta ccaaaatcag ctcgtctgct
    57961 ctcgccttta tttcctggtg cacctaaaat caacattaat ttgcctgtct gatgttcttc
    58021 cacaacgctg agtaattttt ctaagctgtc accattatgg gcataatcaa caaaaacttt
    58081 agcatgatta gtcatggtga ggacttccat acggcctggg acgcgagtct tagcgatgcc
    58141 tttttgaata tcagctaggc tagcacccaa acgaaggcag gcaagtccag ctgccatagc
    58201 attttcttgg ttaaaatggc caattaattg aatgtcataa tggccagcta attgtccttt
    58261 agcttcaaag gagaaagctt ggctagtggt gatctggttg tcagacaagg gaccataaaa
    58321 cacatgctct tgatccgcta cctgatcagc tagaaatgaa aaatgatcca tcccgctatt
    58381 gatcacaaca gctctgctat tctccattaa aagacgctta tgatagaaat aatcttcaaa
    58441 cgttggatgc tcgattgggc caatatgatc aggactaata tttaggaaaa ccccaacatc
    58501 gaacgtaagc ccatagacac ggtcaacgag gtaagcctga ctagaaactt ccataatcaa
    58561 gtgggtcatg ccattagtca cacactcagc catcatagca aaaagatcca agctttcagg
    58621 agttgtaagt tgtgatttga aaaaggtctt gccatctaag gtggtattca tggtagaaaa
    58681 catggcaggt ttataggatt ctttcaacat gtggtaggca aaataagcag ccgtcgtctt
    58741 tcccttagta cctgtaaaag ctagtagttt gagcttttct tgagggttgc catagaaagc
    58801 catggcaatt agactcatag cttttttgat atcagtgacc aaaacaacgg gaataccaag
    58861 ctcgtaatct acctctgaaa tatagagttg taatccgtta gtgattgctt ctttaaggta
    58921 gtcagctttg aaagttgctc ctttagcaaa aaaaagggtc ttgccatcta cttgacggct
    58981 atcgtaactc aagcgctcaa aacttaagcc ttgataatgg tagtggtatc cgtcggcatc
    59041 aagaacctca cgaaaattat ggtctttttt taaaatgtct aataattgtt caatggttat
    59101 cataccctta ttttatcctt aaagttcttg ttttacaagt cacaagcaaa agtttataat
    59161 aaaactaata gaaactagga aagaatagat atgtcgacag aaaaaaaaca actgacacaa
    59221 gaagaattga tggttcaggg agcagcctgg tccacagctg gtaatttcat tagccgactt
    59281 ttgggagtgt tatacattat tccctggtat atttggatgg ggcaatacgc gattcaagcc
    59341 aacgctcttt tcaatatggg gtataatgtt tatgcttatt ttttattgat ttcaaccaca
    59401 ggactcaatg ttgcgattgc taagcaggtt gccaagtaca attccatggg acaaactgag
    59461 catagctatc aattaatccg aagtacccta aaactcatgc ttggtctggg ccttattttt
    59521 tcagtcatta tgtatctggg ctctccttta tttgcgagct tatctggtgg tgatgacaca
    59581 cttgttccca ttatgcacag cctttcttta gcagttttta tttttcctgt aatgagtgtg
    59641 attcgaggta tctttcaagg ccacaataat atcaagcctt atgcgattag tcagattgct
    59701 gagcaactca ttcgggttat ctggatgctt ttgaccacct tttttatcat gaagttaggt
    59761 tcaaaagatt atctatcggc ggtaacgcag tcaaccttgg cagcctttgt gggaatgatt
    59821 gctagtatgg ctgtcttagg ttactacttg tggaagttag gcttgctaaa agcaatatgt
    59881 cgtaagccca atcatcatat tgatagtgac attaaaggac tgttgcttga aaccttaaaa
    59941 gaatccatcc cctttatcgt gacaggaagc gcgattcaag cctttcaatt gattgatcaa
    60001 tggacttttg tcaatactat gactcttttt acagattata gccgttctca attgcttgtt
    60061 ttatttggtt actttaacgc aaacccagcc aaaattacaa tggttttaat tgcagtagca
    60121 gcatctattg gtggtgtagg cattgcctta ttaactgaaa attatgtcaa aaaagatatg
    60181 aaagcagctg ctcgcttaat cattaacaac attgaaatgt tagtgatgtt tttgttaccc
    60241 gctcttactg gggcaattat tttagcaaga cctctatatt ctgtttttta cggagctagc
    60301 gaggatcgtg ctattcacct ctttgtggcg gtcctcttcc aaaccttgct actggcgctt
    60361 tacaccctct tttcaccgat gcttcaagct ctttttgaaa atcgaaaagc gatttactac
    60421 tttgcctatg gtatcttgat taagttagtt ttacagatac cgcttattta tttgctacat
    60481 gcttatggtc ctttactagc gacgacgatt gctttagtgg tgccgattta tttgatgtat
    60541 cgacgcctat atcaggttac tcattttaac cgcaaactgt tgcaaaaacg tttattatta
    60601 accttgattg aaaccttatt aatgggactg gtcgtgtttg tggccaactg gctattgggc
    60661 tatgccttta aaccgacagg ccgcttgacc agccttcttt acctcctcat tattggtggc
    60721 ttgggaatga cggtttacac ggcactcacc ttgctgacgc atcaactaga taaattaatt
    60781 ggtagcaaag ctagtcgcct tcgtcagaaa ttaggctggc attaatataa tgacaccaag
    60841 aacggtttcg tgagtgttta tcgaaatcgt tttttcttaa tgatctcgct tagtaaaggt
    60901 agctgataaa aaatcaggat ttcccaagca aactactgat atttttggta taatgataaa
    60961 agtgtaaaaa aatagaagga agtatatcaa catgggaaaa tgtcaagtta tttcgcatcc
    61021 gcttatccaa cacaaacttt caatcttacg tcgtcaaacc acatcaacta aagattttcg
    61081 tgagttggtt aatgaaattg cgatgctgat gggatatgaa gtgtcacgcg accttccctt
    61141 agaagatgtc gacatccaaa cgccagtctc aaaaacggtc caaaaacagt tagctggtaa
    61201 aaaattagct attgttccga ttcttcgtgc tggtattggg atggttgatg gcttgttaag
    61261 tttggtacca gctgcaaaag ttggccatat cggcatgtac cgtaatgaag aaacccttga
    61321 acctgttgaa tacctcgtta aactaccaga agatattaac caacgacaaa ttttccttgt
    61381 tgatccaatg ttggcaacag gtggttcggc tatcttagca gtggattcgt tgaaaaaacg
    61441 tggcgcagca aatattaagt ttgtctgttt agttgcagca ccagaagggg tgaaaaaact
    61501 tcaagaagct catccagata ttgatatctt cacagcagca cttgatgatc atttaaatga
    61561 acatggctat atcgtgccag gcttgggcga tgctggtgat cgtttatttg ggacaaaata
    61621 aaagagacaa ccatcaaata gtagcctttt taggccaatc gttcttgatt ttgttaaaaa
    61681 aatcagagag atttctcttc tttaaaggaa aagcaagttt atgatttgac ctttattgac
    61741 caaaatatta taataaggac aatcagtaaa aaagagatga cctagtgggt tgccgtctct
    61801 cacaatgacg ctactaaaaa cccttgtaga ttggagaatg tattatgatt cctgttgtta
    61861 ttgaacaaac tagtcgtgga gaacgttctt atgacattta ttcacgttta ttaaaagacc
    61921 gtattatcat gttaacaggg cctgttgaag acaacatggc caactctgtc atagcgcagc
    61981 tcttattcct tgacgcgcaa gacaacacga aagatatcta cctatatgtc aacacaccag
    62041 gtggctctgt ctcagcaggt ttggctattg tcgataccat gaactttatc aaggccgatg
    62101 tgcaaactat tgtcatgggt atggcagctt ctatggggac agtcattgct tcatcaggaa
    62161 caaaaggcaa acgctttatg ttaccaaatg cagagtatat gatccaccag ccaatgggtg
    62221 gcacaggcgg tggcacgcaa caaacggata tggctatcgc agcagaacat ctcttaaaaa
    62281 cacgtcaccg tttagaaaaa atcttagcgc aaaatgctgg aaaaacgatt aaacaaatcc
    62341 ataaagatgc tgagcgtgat tattggatga gtgctgaaga aaccttggct tacggtttca
    62401 ttgatgaaat catggaaaac aacgaactaa aataaagagg atctctgcaa aagtattcta
    62461 gaaacttcta ggatgctttt tctcttagaa aggaaaataa tgatacagcc tactgcatta
    62521 aaacagcttc aagagttaaa acgtcagttc agatcccttt gcaaccaatt atgagatagt
    62581 ttgaggatga tccttagcag ctgtgtgcaa gaagttatga cgatttcata aaggatgacc
    62641 tagccagtct ttcttcgtct cttttactta aagtgtggta taatcagatt atgctagcca
    62701 aaactaaaaa atgcattgcc attaaaggtg ttgtagatcg gcttatccta gatctcataa
    62761 caatgctgta gtaccgccct taccttgcta ctaaaggcgc tgttgaagca caaattgact
    62821 tgcaaaggat cttgactgat aggtatatgt ccggtggaat cgccaaagca gcaaaaagac
    62881 caagaccctt atttggtctc taccaaaata taatagaaaa ggatttagaa tgtttcaaaa
    62941 acaagaacgt attggactcg tcgtttacct gtattataac cgagatgcca gaaagttatc
    63001 aaaatttggt gatttatatt accattccaa gcgctctcgt tacctcatta tttatattaa
    63061 taaaaatgat ttagacacaa aattagaaga aatgagacgt ttgaaatgtg ttaaagacat
    63121 tagaccatca gcttttgatg atattgaccg ccaatttgta ggtaaccttc atcgcgacga
    63181 aacaaacaac catcaaaagg gttaccaacc ccctagttac tgattagcgt ttcagattta
    63241 gttagcttat taaagtaaga aggttttgac agatgctcac actacttcaa gacaatgaga
    63301 caactagagc attagtgaat aactgagttg actgtcactt ctttaataag aacggatagg
    63361 attggtccta aaatagagca ctgcaaagat atgccagtgc tttttagctc attttttgat
    63421 aaaatagaac tactaaaaag tgaaggaaat aagatgatca caggaaaact cataaccgtt
    63481 gaaggtccag atggcgcagg gaaaacgact gttttagagc aactcattcc actgttaaaa
    63541 caaaaagtga ctcaggagat cttgacaaca agagagcctg gaggtgttgc catttcagaa
    63601 tacattagag aacttatttt agacatcaac catactacta tggaccctaa aacagaactc
    63661 ttactttata ttgcggctcg aaggcagcat ttggtggaaa aggtactacc agctcttgaa
    63721 gcaggccagt tggtttttat tgatcgtttc atcgatagtt cagtagctta tcaaggtgcg
    63781 ggacgcggtt tgatcaaagc agacattcag tggctcaacg agttcgcaac agatggttta
    63841 gagcctgact tgacccttta ttttgatgtt ccttctgaaa ttggtttagc acggattaac
    63901 gcgaaccaac aaagagaagt caatcgttta gatttggaaa caatagagat acatcaacga
    63961 gtacgaaaag gatacctagc cttagctaag gagcatccaa aacgtattgt cacaattgat
    64021 gcgactaaac cattgaaaga agttgtctct gtcgctttgg aacatgtctt agccttgctt
    64081 ttagcctagg ataagggagg gtaggaatgg atttagcgca aaaagctcct aacgtttatc
    64141 aagcttttca gacgatttta aagaaagacc gtctgaatca tgcttatctt ttttcgggtg
    64201 attttgctaa tgaagaaatg gctctttttt tagctaaggt catcttttgt gaacagaaaa
    64261 aggatcagac gccctgcggg cattgtcgct cttgtcaatt gattgaacaa ggagattttg
    64321 ccgatgtgac ggtattggaa ccaacagggc aagtgattaa aacggatgtg gtcaaagaaa
    64381 tgatggctaa cttttctcag acaggatatg aaggaaaacg acaagttttt attatcaaag
    64441 attgtgaaaa aatgcatgta aatgccgcta atagcttgct aaaatacatt gaggagcctc
    64501 agggagaagc ttacatgttt ttgctgacca atgatgataa caaagtgctt ccgaccatta
    64561 aaagtcggac acaggttttt cagtttccta aaaacgaagc ctatctcttc cagttagccc
    64621 aagagcgagg tttattaaga agtcaagctg atttagtggc caaactggct aaaaatgttg
    64681 accaattaga agatttggca caaaatagtc attttttaga agtgatggct cagactgaac
    64741 gttttgtttc aatctggtta aaagatcagc tgcaagctta tttagccttg aatcacctgg
    64801 tactgttggc aaccgaaaaa gaggagcaag agttaatttt gacccttttg acactactct
    64861 tggcaagaga gcaatcacaa acgcccttta aacaattgga ggcggtttat caggctaggc
    64921 tcatgtggca gagcaatgtc aattttcaaa acacattaga atatatggtg atgtcagaat
    64981 aagtgcaatt ggaattcgtt atggggaaac gaagcttgtc aaaagacttg cccgtagcga
    65041 ccaaagtagc ggcgcatagg ggcaaaaaag cttttgaaga aaatactgcc cttgcaacag
    65101 atttgatgaa agaagtatca cgattaatga tacaaaatca acttgaaatg acgtttatta
    65161 atagtgtctt tcccttagat cagcatgttg tcctaattcc cttttcagca gaagagcaca
    65221 tggattttta caactgttaa aagatttagc ggccgatttt aggtcaagaa gtgagctgcc
    65281 ccagattaac agccaagaag aaaccaagat ttatgggcgc ttaggaccgt gtggcagacc
    65341 actgtgctgc tttcgttttt gggaaaattt ctgacagtat ctattaaaat actaaaaaat
    65401 caaaggttat cattgacttt gggtaaagca acaagccctt atggccgttt gctttgctgt
    65461 ctctatgatg aaggtggctt ttaccaataa agcaagaaaa aattccctga atatggtacc
    65521 atagtagaga caagtgatgg ccctgcaaca gtagcagccg ttgatatatt tacagatccc
    65581 attaaggtgc ggttaaaaga ccagttgacc ttagtcactt atgctttaga ggaggttaaa
    65641 gtaggtgaat aaaaaagaat tattcgatgc ttttgatgga ttttcccaaa atttaatggt
    65701 tactttagct gaaattgaag ccatgaaaaa acaagtccaa tcactagtag aagaaaacac
    65761 gattcttcgc ctagaaaata caaaactacg ggaacgtttg agtcacctag aacatgaaac
    65821 ggtagctaaa aatccttcca aacaaaggaa ggatcactta gagggaattt atgatgaagg
    65881 gtttcatatc tgcaattttt tctatggaca acgtcgtgaa aatgatgaag aatgtatgtt
    65941 ttgcagagaa ttattagata gaaagtaagg gcatgcaggt tcaaaaaagt tttaaagaca
    66001 aaaaaacaag cggaaccttg tatttggttc caaccccaat tggcaatctg caggacatga
    66061 cctttagagc agtggcaacg ttaaaagagg ttgattttat ttgtgcagaa gacacaagaa
    66121 acacaggtct tttgctaaaa cactttgaca ttgctaccaa gcaaatcagc tttcatgagc
    66181 acaacgccta tgagaagatt cctgatttaa ttgatttatt aatatcagga cggtcactag
    66241 ctcaggtatc tgatgcagga atgccatcga tttctgatcc tgggcatgat ttggtcaagg
    66301 ctgctattga tagtgatatc gcagtcgttg ctttaccagg tgcctcagca gggattacag
    66361 ctttgattgc tagtggactg gctcctcaac cccatgtttt ttatgggttt ttacccagaa
    66421 aagcagggca acaaaaggct ttctttgagg acaaacacca ttacacagaa acacaaatgt
    66481 tttatgaatc accctatcgc atcaaagata ccctgaccaa tatgttggct tgttatggtg
    66541 atcgtcaagt ggtgcttgtt agagaattaa ccaagctttt tgaggagtac caacgggggt
    66601 cgatttcaga aatcttgtcc taccttgagg aaacacccct aaaaggggag tgtctgctga
    66661 ttgtggctgg agcccaagta gacagtgaga ttgagctgac agctgatgtt gacttagtgt
    66721 ctctagtgca aaaagaaatc caagcaggag ccaagccaaa tcaggctatt aaaacaattg
    66781 ctaaagctta ccaggtaaat cgccaagagc tttaccaaca atttcatgac ttataagtca
    66841 tcgtagatta ggagaaaaac aaatgacaga agatcaagca actatcctta ttttaggagt
    66901 atacggaatc atattggctg tattcttatt atcagcttta ttatgcctta tcgctaactg
    66961 gcgactcttt aaaagagcag gttacaaagg atggtatagt ctcattcctt tctatgcagg
    67021 ttttgtcaaa cacaaaatca cttttggaga agataataaa tggttttact ttattggttg
    67081 ggtcattgct atttattatt actatgtgca cttttgctat gtccgtgctt ttggtggatc
    67141 aaagggtcta gcagtatttg gcttgttttt cccaggcatt gcttctttga tagtggcttt
    67201 tggaaaaact tataccacac aagaatgcca ccctgtgcca catcttttaa actaagagaa
    67261 aaaagaccat caattggatt tattgatggt cttttaggtg tttaaatgat tttagtcccg
    67321 tgaacaatgg ccgttccagt gagttgactc aagttttggc aattctcagc agtgacgcct
    67381 cctccaatca tgatttcaat gcgtttattg gcataggtca caagactttt aagctgttcc
    67441 acattatctg taataggagt agcttcaggg gagccatgag ttaacacacg cacaaagcca
    67501 taatcaatca gttgatcaag cgcttggtgc tggtggtcag tcggaatatg gtcaaaagcc
    67561 atgtggaaaa ccagtggcaa gccttgtgta gcaggcagta actgctcgat agcgtcggta
    67621 tcaaggtgat tttctgtggt cagcaagcct aagactagcg catctgagcc agcttcaaca
    67681 gcttttaaga tatcttcttc catagctttt agttcgaggt cgttatagac aaaatcgcca
    67741 ccgcgaggtc gaatcatggt cgctacgcta atctttttat cgtgtaagag ctgacaggct
    67801 tctttgatga cgccataaga tggtgttgtt cccccgacag ctaggttatc acagagttcc
    67861 acacgactga cttgaccagc atcaagggtt ggcagtagtg tgaggttctc agcacaaaat
    67921 tctttaatca tttttagatc tcctttatca ctaatattat agcacgaatg aagctagtca
    67981 tcaggaaaca tttttgtcaa atcatggaca ttatgttata ctcactagta ttaaaagtag
    68041 gccaaaacag cagcaaatac tttgaaaaaa gattgctatg ttctacggca atatcagtct
    68101 ttaccaacga actctcaaga agaaaagaaa gacaaagctt agcattttaa aaaagccccc
    68161 ctttttttgt gaaatgatga ccaaaaacag gcgcctcacg cctaaaacag ttaccctaaa
    68221 ggagaacaaa tgattacgat ttaccaatac ccaaaatgta gtacctgtca aagagccatg
    68281 gctgaactaa agcaactggt tagtgacttt gaagtcattg acatcaaagc taatccaccc
    68341 aaagctcagg acctcaaaca ttggatggaa acatctggtt ataccatcaa aaatttcttt
    68401 aataccagtg gtaacagcta ccgcgaattg ggacttaaag ataaaataga ccagcttagc
    68461 cttgataaag ctgctgaact cttagccaca gatggtatgc tgattaaacg gcctattctg
    68521 attaaggacg gtagagtcct acaagttggc tatcgcaagc catatcaaga gttggattta
    68581 ggataatgcg acaaagtctc aaaaaaggac aaggcaacat tataacgcct tgtccttttt
    68641 tgggatctgt ttttagaaat tagagatcaa tatctagtaa aattggcgta tggtcttggc
    68701 gttccccaga agaaatcatt tcagaacgct taaccttatc cacaagtcgg tttgaagcta
    68761 gccaatagtc aattctccaa ccggtattat tgattttgct ggttttgcta cgttgtgccc
    68821 accaggtata aacatgagga atatcgccgt gcaagtgacg aaaagtatct gtaaagcctc
    68881 ttgctaatag gttagtaaag ccttgacgtt cttcgtcggt aaaaccaggg gaacgtcgat
    68941 tgctgcttgg atttgccaaa tcaatctctt tgtgggcaac gttgtaatct cccgtagcca
    69001 aaacaggctt ttgagcatcc agttcagtca agtaatcagc gtatttgtgg tcccaaattt
    69061 gacggtcatc taaacgtcta aggccatcac cagcattagg cgtgtaaacc tgtgtgacga
    69121 aaaagtcttc aaattctagg gtaatgatac ggccctcagc atccattgtt gttggggcac
    69181 caatttctgg aaaagtaatg acagggttta gcgtgttttt gtacaggaac atggtgccag
    69241 catagccttt cctagcaggc tcaactgaag aacgccacac atgcaaatag tttggaaagt
    69301 aactaagtaa ggcctcgata tgttttttgg taggcccctt agcagataat ttggtttctt
    69361 gaatggcaat aatatccgca tcttgagcga ctaaagtgtc taaaacagcg cgtgataaaa
    69421 gcgcacgagg ggactctcct gtgagagcag catttaagga atcaatgttc catgaaatca
    69481 gtttcatttg gtatctcttt ctaacagata gtcttgttgt tattgtaaca aaaaacgaaa
    69541 cgataagcga ctttggacac ctagccccca taaaacagtc tagccaaatg aagcatagca
    69601 gcgtaagaac aagataagga ggtgatcagt gagcatatcg tttgacagtt aagagtagga
    69661 ttactataat agaagcataa atgtaagcgc taacaaaata aaaaatatag gagaatgtca
    69721 atggcacaaa aaacagtcat caccgaggaa acaaccgatt ttgttatgga tttcaaaaca
    69781 agtagcgctg agggaaatgt tgattttatt aacgtttttg accttgagaa aatggcacaa
    69841 caggtcatcc ctaaaggagc ctttggttat attgctagtg gtgctggtga tacctttacc
    69901 ctccatgaaa atattcgctc atttaatcat aaattaattg tccctcactc cctcaaaggg
    69961 gttgaaaatc cgtcaacaga gattacgttt gatggtgatc acttaacctc tcctcttatt
    70021 ttagcacctg tagcggctca taaactggcc aatgaacaag gagaagtagc gtctgccaaa
    70081 ggattgaagg aatttggaag tatctacacc actagttcct actcaacaac tgacctgcca
    70141 gaaatcagtg ctgccttagg tgggacaccc cattggtttc aattttatta cagtaaagac
    70201 gatggcatta atcgtaatat tatggatcgt gtcaaagcac aaggttgcaa agctatcgtc
    70261 ttgacagcag atgcaacagt tggaggaaac cgcgaagttg ataggcgaaa cggttttgtt
    70321 tttccggtcg gtatgccaat tgttcaagaa tatttacctg atggtgcagg taaaacaatg
    70381 gattatgtct ataaatcagc taaacaagcg cttacctcaa aagatattga atatatcgca
    70441 acctactcag gactgcctgt ttatgtcaaa ggaccacagt gtgctgagga taccttgcgg
    70501 gcattggacg caggagcatc aggtatctgg gtaaccaatc atggtggccg tcaattagat
    70561 ggtggtccag ctgcttttga ttccttacaa gaagtcgctg aagcagttga tcaaaaagtt
    70621 cctattgtct ttgactcagg tataagacgg ggtcaacata ttttcaaagc tcttgcttca
    70681 ggtgctgacc ttgttgcctt ggggcgtcca gcaatttacg gcttggctat gggaggaagc
    70741 actggtactc gtcaggtctt tgaaaagtta aatgacgagt taaaaatggt tatgcaactg
    70801 gctgggacac aaactatcca agatgttaaa gcctttaacc ttcgccataa tccgtatgat
    70861 tcatcgattc catttgatca aaatgcgcta cgcttagatt aaaacagaca aaaacctctg
    70921 ctatcatgtc acaaatagta gaggttttac actgcaaaaa gaggtatgaa aatccaataa
    70981 catagttaca aggctatcgt ttaccacccc actaatagat taaaatgaaa gacttcttac
    71041 attaatagaa gtttctgttg cttttctcag aaaaatgtgg ttaaataatc aaatattatt
    71101 aacgaaaaat gagttaatga ttaacattaa actggtttta gttaaaacat ttaggagggt
    71161 atcaggtgga gaaaaagcaa cgtttttccc ttagaaaata caaatcagga acgttttcgg
    71221 tcttaatagg aagcgttttc ttgatgatga caacaacagt agcagcagat gagctaacca
    71281 caacgagtga accaacaatc acgaatcacg ctcaacaaca agcgcaacat ctcaccaata
    71341 cagagttgag ctcagctgaa tcaaaacctc aagacacatc acaaatcact cccaagacaa
    71401 atcgtgaaaa agagcaatca caagatctag tctctgagcc aaccacaact gagctagctg
    71461 acacagattc agcaccaatg gctaatacag gttctgatgc gactcaaaaa agcgcttctt
    71521 taccgccagt caatacagat gttcacgatt gggtaaaaac caaaggagct tgggacaagg
    71581 gatacaaagg acaaggcaag gttgtcgcag ttattgacac agggatcgat ccggcccatc
    71641 aaagcatgcg catcagtgat gtatcaactg ctaaagtaaa atcaaaagaa gacatgctag
    71701 cacgccaaaa agccgccggt attaattatg ggagttggat aaatgataaa gttgtttttg
    71761 cacataatta tgtggaaaat agcgataata tcaaagaaaa tcaattcgag gattttgatg
    71821 aggactggga aaactttgag tttgatgcag aggcagagcc aaaagccatc aaaaaacaca
    71881 agatctatcg tccccaatca acccaggcac cgaaagaaac tgttatcaaa acagaagaaa
    71941 cagatggttc acatgatatt gactggacac aaacagacga tgacaccaaa tacgagtcac
    72001 acggtatgca tgtgacaggt attgtagccg gtaatagcaa agaagccgct gctactggag
    72061 aacgcttttt aggaattgca ccagaggccc aagtcatgtt catgcgtgtt tttgccaacg
    72121 acgtcatggg atcagctgaa tcactcttta tcaaagctat cgaagatgcc gtggccttag
    72181 gagcagatgt gatcaacctg agtcttggaa ccgctaatgg ggcacagctt agtggcagca
    72241 agcctctaat ggaagcaatt gaaaaagcta aaaaagccgg tgtatcagtt gttgtagcag
    72301 caggaaatga gcgcgtctat ggatctgacc atgatgatcc attggcaaca aatccagact
    72361 atggtttggt cggttctccc tcaacaggtc gaacaccaac atcagtggca gctataaaca
    72421 gtaagtgggt gatccaacgt ctaatgacgg tcaaagaatt ggaaaaccgt gccgatttaa
    72481 accatggtaa agccatctat tcagagtctg tcgactttaa aaacataaaa gatagcctag
    72541 gttatgataa atcgcatcaa tttgcttatg tcaaagagtc aactgatgcg ggttataacg
    72601 cacaagacgt taaaggtaaa attgctttaa ttgaacgtga tcccaataaa acctatgacg
    72661 aaatgattgc tttggctaag aaacatggag ccctgggagt acttattttt aataacaagc
    72721 ctggtcaatc aaaccgctca atgcgcctaa catctaatgg gatggggata ccatctgctt
    72781 tcatatcgca cgaatttggt aaggccatgt cccaattaaa taccaatggt acaggaagtt
    72841 tagtgtttga cagtgtggtc tcaaaagcac cgagtcaaaa aggcaatgaa atgaatcatt
    72901 tttcaaattg gggcctaacc tctgatggct atttaaaacc tgacattact gcaccaggtg
    72961 gcgatatcta ctctacctat aacgataacc actatggtag ccaaacagga acaagtatgg
    73021 cctctcctca gattgctggc gccagccttt tggtcaaaca atacctggaa aagactcagc
    73081 caaacttgcc aaaagaaaaa attgctgata tcgttaagaa cctattgatg agcaatgctc
    73141 aaattcatgt taatccagaa acaaaaacga ccacctcacc gcgtcagcaa ggggcaggat
    73201 tacttaatat tgacggagct gtcactagcg gcctttatgt gacaggaaaa gacaactatg
    73261 gcagtatatc attaggcaac atcacagata cgatgacgtt tgatgtgact gttcacaacc
    73321 taagcaataa agccaaaaca ttacgttatg acacagaatt gctaacagat catgtagacc
    73381 cacaaaaggg ccgcttcact ttgacttctc gctccttaaa aacgtaccaa ggaggagaag
    73441 ttacagtccc agccaatgga aaagtgactg taacggttac catggatgtc tcacagttca
    73501 caaaagagct aacaaaacag atgccaaatg gttactatct agaaggtttt gtccgcttta
    73561 gagatagtca agatgaccaa ctaaatagag taaacattcc ttttgttggt tttaaaggac
    73621 aatttgaaaa cttagcagtt gcagaagagt ccatttacag gttaaaatct caaggcaaaa
    73681 ccggttttta ctttgatgaa tcaggtccaa aagacgatat ctatgtcggt aaacacttta
    73741 caggactcgt cactcttggg tcagagacca atgtgtcaac caaaacgatt tctgacaacg
    73801 gtctacacac acttggtacc tttaaaaatg cagatggcaa atttatctta gaaaaaaatg
    73861 cccaaggaaa ccctgtctta gccatttctc caaatggtga taacaaccaa gattttgcag
    73921 ccttcaaagg tgttttcttg agaaaatatc aaggcttaaa agcaagtgtc taccatgcta
    73981 gtgacaagga acacaaaaat ccactatggg tcagcccaga aagctttaaa ggagataaaa
    74041 actttaatag tgacattaga tttgcaaaat cgacgaccct gttaggcaca gcgttttctg
    74101 gaaaatcgtt aacaggagct gaattaccag atgggtatta tcattatgtg gtgtcttatt
    74161 acccagatgt ggttggtgcc aaacgtcaag aaatgacatt tgacatgatt ttagaccgac
    74221 aaaaaccggt actaccacaa gcaacatttg atcctgaaac aaaccgattc aaaccagaac
    74281 ccctaaaaga ccggggatta gctggtgttc gcaaagacag tgtcttttat ctagaaagaa
    74341 aagacaacaa gccttataca gttacgataa acgatagcta caaatatgtc tcagtagaag
    74401 acaataaaac atttgtggag cgacaagctg atggcagctt tatcttgccg cttgataaag
    74461 caaaattagg ggatttctat tacatggtcg aggattttgc agggaacgtg gccatcgcta
    74521 agttaggaga tcacctacca caaacattag gtaaaacacc aattaaactt aagcttacag
    74581 acggtaatta tcagaccaaa gaaacgctta aagataatct tgaaatgaca cagtctgaca
    74641 caggtctagt cacaaatcaa gcccagctag cagtggtgca ccgcaatcag ccgcaaagcc
    74701 agctaacaaa gatgaatcag gatttcttta tctcaccaaa cgaagatggg aataaagact
    74761 tcgtggcctt taaaggcttg aaaaataacg tatataatga cttaacggtt aacgtatacg
    74821 ctaaagatga ccaccaaaaa caaaccccta tctggtctag tcaagcaggc gctagtgcat
    74881 cagctattga aagtacagcc tggtatggca taacagcccg aggaagcaag gtgatgccag
    74941 gtgattatca gtatgttgtg acttatcgtg acgaacatgg taaagaacat caaaagcagt
    75001 acaccatatc tgtgaatgac aaaaaaccaa tgatcactca gggacgtttt gataccatta
    75061 atggcgttga ccactttact cctgacaaga caaaagccct tggctcatca ggcattgtcc
    75121 gcgaagaagt cttttacttg gccaagaaaa atggccgtaa atttgatgtg acagaaggta
    75181 aagatggtat cacagttagt gacaataaga tgtatatccc taaaaatcca gatggttctt
    75241 acaccatttc aaaaagagat ggtgtcacac tgtcagatta ttactacctt gtcgaagata
    75301 gagctggtaa tgtgtctttt gctaccttgc gtgacctaaa agcggtcgga aaagacaaag
    75361 cagtagttaa ctttggatta gacttaccgg tccctgaaga caaacaaata gtgaacttta
    75421 cttaccttgt gcgggatgca gatggtaaac cgattgaaaa cctagagtat tataataact
    75481 caggtaacag tcttatcttg ccatacggca aatacacggt cgaattgttg acctatgaca
    75541 ccaatgcagc caaactagag tcagataaaa tcgtttcctt taccttatca gctgataata
    75601 acttccaaca agttaccttt aagatgacga tgttagcaac ctctcaaata actgcccact
    75661 ttgatcatct tttgccagaa ggcagtcgcg ttagccttaa aacagctcaa ggtcagctga
    75721 tcccgcttga acagtccttg tatgtgccta aagcttatgg caaaaccgtt caagaaggca
    75781 cttacgaagt tgttgtcagc ctgcctaaag gctaccgtat cgaaggcaac acaaaggtga
    75841 ataccctacc aaatgaagtg cacgaactat cattacgcct tgtcaaagta ggagatgcct
    75901 cagattcaac tggcgatcat aaggttatgt caaaaaataa ttcacaggct ttgacagcct
    75961 ttgccacacc aaccaagaca acgacctcag caacagcaaa agccctacca tcagcgggtg
    76021 aaaaaatggg tctcaagttg cgcatagtag gtcttgtgtt actcggactt acttgcgtct
    76081 ttagccgaaa aaaatcaacc aaagattgat aacaaaacgc aaagagacaa caaatcatcc
    76141 cttttaacag tcggaccttt ctttgaaatt gagctggcag atgatcattt cttaacaaaa
    76201 gttaaagagt tgagcaaagt aaggaacaga cataaagacc ataaaagcaa gccagtttgg
    76261 cttgctttta tggtgttatt gtcgtgtgct acgatgacta aaaaagaaca acgaacaatg
    76321 acctcgaatc accaaaagga cttgatttga tagcttccct atgctatact aagcctattc
    76381 tttcaagaag gactcctttt gtggaaaaga ctgaaaaaaa ggacactaat ctatccaaaa
    76441 actccagatg agtagctgca accggatgcc tctgctgtga tcaaggtgat aaagcagact
    76501 ggcttgtcac tacctgagca ggtgtcaaaa aaagaagctt tggctttgtc attcaacata
    76561 ctgagcttca gtctttcaga acggagacac ccccagtttt gtactcaaaa agcataaaca
    76621 gctctgctga tgcgacatcc gatttctacg tccgcagtga gccaaaccag ctgctgtttg
    76681 ctatggaaaa agtggcgcca atcgggattt ttgagaccct aggctcaaaa ataaggcata
    76741 gaatcccaaa ggaagtcgct gccgtgagca caacctaaga aaaactatcc caaaagactt
    76801 tttctgcaat ttgaaatact gaatttcagt attttttctt ttgtaactaa gagcaatgaa
    76861 tgaggtaaaa aaggcaacaa tgtcaaaaaa gaaacgaaaa cactatcagg tttatgaggg
    76921 attacgctgt gctatgacgc tttgttttat cagtggctat gtcaatgcct ttacctatat
    76981 gacacaaggc aaacgttttg caggtgttca gacaggcaat cttttgtcat ttgccattcg
    77041 cttgtcagaa cagcaactga aggaggcact gcaattttta cttcccatga tagtttttat
    77101 gcttgggcag tcctttactt atttcatgca ccgctgggcc actaaaaagg gactccactg
    77161 gtatctctta tcaagcgtta tgttaacagg acttgctttt ggaacggccc tattcacgcc
    77221 ttttcttcct tccaatgtta cggtagcagc tttagccttt tttgcctcta ttcaggttga
    77281 tacgtttaaa accttacgag gagctagcta tgctaatgtg atgatgacag gaaatatcaa
    77341 aaatgccgcc tatttactaa ccaaaggctt gtacgaaaaa aatcacgaac taacacatat
    77401 cggacgcaac accttaatag tcatcttggc ttttgctgtt ggagtggttt gttcgacgtt
    77461 gctttgcata gcttatggcg aatatgcttt gatgcctatt ttaatgcctt tactctatgt
    77521 caattacctg ttggctcagg aattttatca cattcaaacc aaaatcaaac cgattaaaag
    77581 aacttaacgg aattgtggag aaagaaagtt catttagggt aagtttttac tgcccctcct
    77641 t
//
LOCUS       DAUCXI010000003        73755 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.003, whole genome shotgun sequence.
ACCESSION   DAUCXI010000003 DAUCXI010000000
VERSION     DAUCXI010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 73755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73755
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.003"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(314..729)
                     /locus_tag="VGY43_000160"
                     /pseudo
     CDS             complement(314..729)
                     /locus_tag="VGY43_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1150..1683)
                     /locus_tag="VGY43_000161"
     CDS             complement(1150..1683)
                     /locus_tag="VGY43_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEQ4301387.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            complement(1763..2539)
                     /gene="recX"
                     /locus_tag="VGY43_000162"
     CDS             complement(1763..2539)
                     /gene="recX"
                     /locus_tag="VGY43_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEQ4301388.1"
                     /translation="MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIEDLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            2654..4009
                     /gene="rlmD"
                     /locus_tag="VGY43_000163"
     CDS             2654..4009
                     /gene="rlmD"
                     /locus_tag="VGY43_000163"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ4301389.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIFC
                     QITAVKRNFAEAKLLTVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLANFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
     gene            4674..6029
                     /gene="rocA"
                     /locus_tag="VGY43_000164"
     CDS             4674..6029
                     /gene="rocA"
                     /locus_tag="VGY43_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HEQ4301390.1"
                     /translation="MLEDFLQFLGFIFLDIIEIMLTLKLFSFVSAIPLRLKNIFYLSL
                     SMVLFQVVFWAFFPDHFILDVVMLAQFLFFALIALYYGKSIKAKFLMFYAFFPLVSIS
                     LVKRFIVFFVMPLFGMPYSVVKHNTLLIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQ
                     SHRASKLLVFTNSSMALYYLCVQGIDVMSPSLSGLATTTARSIIVLFYFILFLTLLIH
                     LERYVKQNSIEAIVQQKEYRELINYSQHLGLLYQDIQELRQLLTTVSSRLKIGIEQND
                     ISIVRLTYEGILNAEKNNAKDDRLDLTCLDKLQVEAIRHIVLAKLIEAKNKKLKVEVS
                     IPNCIATFFLEVVDLTKLLSFLLDNAIEMSLETKQPCLSIAFLDQNHKLVIVIQSSTK
                     QGQDDSQSVFAIPALKKRDDWQFDLRNVTTILNRYDYLTISSQIHDGILTQLIEIAKP
                     D"
     gene            complement(6130..8835)
                     /locus_tag="VGY43_000165"
     CDS             complement(6130..8835)
                     /locus_tag="VGY43_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEQ4301391.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDP
                     DFHSFHLDGQTIILDDYLKVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NILIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTREKYSSQFSEISWQGPDDSHILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENL
                     STVQGEITSQETDGWYTLTNTASARIYLKQANTRVSRQLENITEPLATMAYDVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAI
                     DTSDFPTDSQPFLLFNTSGHSKTSVTELTLTWKKYYFGQRFPKEVYQEAQEYLAELSQ
                     SFQVIDVSGNTISEADILDTSIAFDYDLSKRTFREPYFAIKVRLRLPITLPAMSWKAL
                     ALQLGNETAPSATVPLYDDSNQCLENEFLKVMIQTDGRLTITDKQSGLIYQDLLRFED
                     CGDIGNEYISRQPNHDQPFYADQGTTKLNIISNTAQVAELEIQQTFAIPVSADKLLQA
                     EMEAVIDITERQSGRSQEKAELTLTTLIRMEKNNPRLQFTTSFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPNAAFWKNPSNPQHQECFVSLFDGEKGVTIGNYGLNE
                     YEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWR
                     AQEGQVPILVEQTSHHKGSLRAEHSYVTGADDQVALTAFKRRLADNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(8850..10136)
                     /locus_tag="VGY43_000166"
     CDS             complement(8850..10136)
                     /locus_tag="VGY43_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEQ4301392.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFTNTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANGKGHQTDRTQMNPWIWERKYEIDSLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNEPVATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCAKDDPIYLATRRTILSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALVLQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSIAP"
     gene            10269..11309
                     /locus_tag="VGY43_000167"
     CDS             10269..11309
                     /locus_tag="VGY43_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ4301393.1"
                     /translation="MTKLLYKKIYHFIKEQIASGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAEKQVTSPEANKDLLLILPFASDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLIQKITQVG
                     LSIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            11360..13054
                     /locus_tag="VGY43_000168"
     CDS             11360..13054
                     /locus_tag="VGY43_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HEQ4301394.1"
                     /translation="MTIYHALKDYQEVMTRGDYLVFDTPLTCRFIGRFFRFENQKALL
                     AELATSKYFQWIEEGQAEVTMKHFFNRQLAKDAFTLKVSEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGDKLYLPIVSVKHSPSFPMRGIIEGFYGTPWTREERIDCLRFIGNKRM
                     NTYMYAPKDDDYQRKLWRDLYPEDWVTYFKELLVVAKEEGIDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVAFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQSDYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSNSWLETLTDYTGDAELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKDVSTLSAWVDELVERANTLRKLDKPAFQQAIVPWFERVAKDQDFWQAI
                     LEQGPHLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            13079..14521
                     /locus_tag="VGY43_000169"
     CDS             13079..14521
                     /locus_tag="VGY43_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ4301395.1"
                     /translation="MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYD
                     YVGPDTASDAYHQIESDLALLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQVYGGWESKHVVDLFVAFSKVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRRGPAELSDGR
                     IGTILNLTPAYPASQSEADTAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEEMALIAENRVDYLGLNFYHPKRVKAPDAIPVISPSWSPEWYYDPYLMPGRRMN
                     VDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIQF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(15132..16010)
                     /locus_tag="VGY43_000170"
     CDS             complement(15132..16010)
                     /locus_tag="VGY43_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ4301396.1"
                     /translation="MSLLCLDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAISSPGAVNKEKGVIEGASAIPYIHHFKIQEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVIGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALTEQGDPLALKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            16207..17157
                     /locus_tag="VGY43_000171"
     CDS             16207..17157
                     /locus_tag="VGY43_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ4301397.1"
                     /translation="MTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIAFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLTGSG
                     ADPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            17167..18093
                     /locus_tag="VGY43_000172"
     CDS             17167..18093
                     /locus_tag="VGY43_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ4301398.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            18174..19619
                     /locus_tag="VGY43_000173"
     CDS             18174..19619
                     /locus_tag="VGY43_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ4301399.1"
                     /translation="MKKWQKIVCVTGTVLSASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKTQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDDFVAKDK"
     gene            19925..20530
                     /locus_tag="VGY43_000174"
     CDS             19925..20530
                     /locus_tag="VGY43_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEQ4301400.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTITYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     TLVTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            20520..22244
                     /locus_tag="VGY43_000175"
     CDS             20520..22244
                     /locus_tag="VGY43_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ4301401.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQLQNDITLRVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADRVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRNDNALSIKALDETDHLLIQVLDN
                     GRGISQERLADMEKRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDA"
     gene            22244..23728
                     /locus_tag="VGY43_000176"
     CDS             22244..23728
                     /locus_tag="VGY43_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4301402.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDCLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQG
                     LPAAALTGFTVLYLDCQEWQAAIDAYFEREGQPFYLKKEEDKKVYLAVLLGKTDQAKA
                     FTYDLQKRFSRNMHQLILGETVDDWENVYESYNQVLKSLFYNCEVSPIRAKDKSKIEL
                     PESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHDSQSIDRILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            23658..27164
                     /locus_tag="VGY43_000177"
     CDS             23658..27164
                     /locus_tag="VGY43_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEQ4301403.1"
                     /translation="MVYRQKSSEIVTRTITKPSRAISNVKQEIDMTPDSKEQTVTGYQ
                     YHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSNWQVIHLPHDFSLKQPYTRNAEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFSLNQSIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFMANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENANYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWIAAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYASGKDYDKLHEEHSDWLLYGSET
                     ASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNVTDYGRKAFHTYSTPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSRGELVSHAQDWLKVQVEGPAHLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKVSQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKVSTPHILITSYQHY
                     LSLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLATSQKRLTYCYQYDTVQAIGA
                     ISLQNHTDTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLVVT
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            27302..28180
                     /locus_tag="VGY43_000178"
     CDS             27302..28180
                     /locus_tag="VGY43_000178"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ4301404.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEIRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            28432..29187
                     /locus_tag="VGY43_000179"
     CDS             28432..29187
                     /locus_tag="VGY43_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEQ4301405.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCQIDAVDLNPKVVKEAQERVTVEGLTRHITVSQANALSLPF
                     PDNHFDIVINEAMLTMLNAKAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLEEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            29240..29578
                     /locus_tag="VGY43_000180"
     CDS             29240..29578
                     /locus_tag="VGY43_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ4301406.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAAIPHALYAVEAFQ
                     MLLVVVKPEA"
     gene            29580..29885
                     /locus_tag="VGY43_000181"
     CDS             29580..29885
                     /locus_tag="VGY43_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEQ4301407.1"
                     /translation="MIENLSQLVQYHDHQVASRSLSRLLGLSQSIVLYAMAQGESISQ
                     ETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKAHHLEAKTDCKLLQVLLD"
     gene            complement(30321..31394)
                     /locus_tag="VGY43_000182"
     CDS             complement(30321..31394)
                     /locus_tag="VGY43_000182"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEQ4301408.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSLKRVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKSLTNMIGSIYPPE
                     AVIISTTFLETLPQREFSCGISEMLKIGFIHDRPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKRIVEQDEFENGLRMSLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(31450..32202)
                     /locus_tag="VGY43_000183"
     CDS             complement(31450..32202)
                     /locus_tag="VGY43_000183"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEQ4301409.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKILSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            complement(32443..32513)
                     /locus_tag="VGY43_000184"
     tRNA            complement(32443..32513)
                     /locus_tag="VGY43_000184"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32479..32481),aa:Thr,seq:ggt)
     gene            32680..32934
                     /locus_tag="VGY43_000185"
     CDS             32680..32934
                     /locus_tag="VGY43_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEQ4301410.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            32955..33350
                     /locus_tag="VGY43_000186"
     CDS             32955..33350
                     /locus_tag="VGY43_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEQ4301411.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVGNLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            33635..33954
                     /locus_tag="VGY43_000187"
                     /pseudo
     CDS             33635..33954
                     /locus_tag="VGY43_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264372.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            33951..34514
                     /locus_tag="VGY43_000188"
     CDS             33951..34514
                     /locus_tag="VGY43_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ4301412.1"
                     /translation="MNLIIIGAQASGKMTIGQEVARQTGMTLFHNHDSIDFVLRFMPW
                     SQESTALIERIRFAFFETFAKTGQDMIFTIVIDFNDPNDVAMLEKIQAVFQSYDQEVL
                     FVELKTDIEERLKRNRTENRLKHKPLKRNIEWSEQDIQSTMAYAVFNPEEPPKTLTHY
                     QKINNTQLTAAETAQLIIQKMTHIKEN"
     gene            34516..37164
                     /locus_tag="VGY43_000189"
     CDS             34516..37164
                     /locus_tag="VGY43_000189"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEQ4301413.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQGI
                     SRYDLGRDKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAAVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIL
                     RLLHPIMPFVTEEIYAQYAQGSIVTVDYPVVRPAFENEAAHKGVESLKDLIRAVRNAR
                     AEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFLANAKPEVVQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            37318..39724
                     /gene="cas3"
                     /locus_tag="VGY43_000190"
                     /pseudo
     CDS             37318..39724
                     /gene="cas3"
                     /locus_tag="VGY43_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
     gene            39857..40585
                     /gene="cas5c"
                     /locus_tag="VGY43_000191"
     CDS             39857..40585
                     /gene="cas5c"
                     /locus_tag="VGY43_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEQ4301414.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DATYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            40585..42480
                     /gene="cas8c"
                     /locus_tag="VGY43_000192"
     CDS             40585..42480
                     /gene="cas8c"
                     /locus_tag="VGY43_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEQ4301415.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRNNEPVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMVDKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QSQYDSFHKQLNNWIDYCEEGDVKRFLTIVQQFILKPEFLTLILDSLIGPDYQHNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEANRENLGI
                     CNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLENKNTITWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSKFGKSRLRTPTVHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            42485..43333
                     /gene="cas7c"
                     /locus_tag="VGY43_000193"
     CDS             42485..43333
                     /gene="cas7c"
                     /locus_tag="VGY43_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEQ4301416.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKSIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKANALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTGFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYNQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTV
                     EILEGL"
     gene            43335..44009
                     /gene="cas4"
                     /locus_tag="VGY43_000194"
     CDS             43335..44009
                     /gene="cas4"
                     /locus_tag="VGY43_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEQ4301417.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQV
                     LHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            44006..45031
                     /gene="cas1c"
                     /locus_tag="VGY43_000195"
     CDS             44006..45031
                     /gene="cas1c"
                     /locus_tag="VGY43_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEQ4301418.1"
                     /translation="MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGI
                     VCFSYLGVSPALVKLCTENQIKLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREE
                     SLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVK
                     ENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLE
                     SYPPFMV"
     gene            45042..45335
                     /gene="cas2"
                     /locus_tag="VGY43_000196"
     CDS             45042..45335
                     /gene="cas2"
                     /locus_tag="VGY43_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEQ4301419.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   45484..45911
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=45484..45515
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaat"
     gene            46071..46781
                     /gene="ccdA2"
                     /locus_tag="VGY43_000197"
     CDS             46071..46781
                     /gene="ccdA2"
                     /locus_tag="VGY43_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEQ4301420.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGALVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHMLLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            46794..47417
                     /locus_tag="VGY43_000198"
     CDS             46794..47417
                     /locus_tag="VGY43_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEQ4301421.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKYIGYAKKSDIKKTLKGIH"
     gene            47460..48566
                     /gene="msrB"
                     /locus_tag="VGY43_000199"
     CDS             47460..48566
                     /gene="msrB"
                     /locus_tag="VGY43_000199"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ4301422.1"
                     /translation="MEHKWKLWLFIVGMVLLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKADPNAPVDQKMIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKADL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEEYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE"
     gene            48654..49394
                     /locus_tag="VGY43_000200"
     CDS             48654..49394
                     /locus_tag="VGY43_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ4301423.1"
                     /translation="MYSLLIVEDEYLIRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIILTDINMPKLNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLQQKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQLGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            49391..51124
                     /locus_tag="VGY43_000201"
     CDS             49391..51124
                     /locus_tag="VGY43_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ4301424.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITTLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNSEIQDFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVSTNPQLIMKTSSDMMAEPWYKAAIDRQAMPILTPARQLSLSS
                     KKEWVVSVTQEVVDAAGHNLGVIRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGTGLLACLICGFATVLVLRRWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVEVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGK
                     GIEDSSLTNSQSLLTRGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMH
                     ELMADDTQENE"
     gene            51197..52276
                     /locus_tag="VGY43_000202"
     CDS             51197..52276
                     /locus_tag="VGY43_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEQ4301425.1"
                     /translation="MSLATDYFSRQTPIVEKLVAYGFEKRDNGYFYNERFMEGEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAAWQGTYTGQVRAAYLELLERLSVACFEVTP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPER
                     LVGQTCEVMTVKVNPKDLPQLLQQEGIYPAYHMSKNNWVSVVLDDKVTDDQLWGLATQ
                     SRQLVNPNGLSNPNSPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYI
                     TAPVKSIRYACQVLETDIPNEGYRKNLNIDKLMRLRKCQQYKDGLLSFDLMKEHGVAA
                     VRGPRRLSPQLIAFLKEKEYFKENN"
     gene            52290..53006
                     /locus_tag="VGY43_000203"
     CDS             52290..53006
                     /locus_tag="VGY43_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEQ4301426.1"
                     /translation="MVEFVADQSFWELFPDAKLGVVLLKDVQNQAESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVTEHTKNAFLIIEALDQEGQNRLQEALDFIEGSAKMYLHA
                     TPSLHVLDKDNPHVPLFTEN"
     gene            complement(53173..53646)
                     /locus_tag="VGY43_000204"
     CDS             complement(53173..53646)
                     /locus_tag="VGY43_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ4301427.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            53788..54468
                     /locus_tag="VGY43_000205"
     CDS             53788..54468
                     /locus_tag="VGY43_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ4301428.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDK
                     DYFLQYTK"
     gene            54742..55977
                     /gene="arcA"
                     /locus_tag="VGY43_000206"
     CDS             54742..55977
                     /gene="arcA"
                     /locus_tag="VGY43_000206"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEQ4301429.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            56077..56517
                     /locus_tag="VGY43_000207"
     CDS             56077..56517
                     /locus_tag="VGY43_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ4301430.1"
                     /translation="MTDKFDANDETRTVYAVVYDNDQPVSTGQFLAETKIEARLTRIV
                     TLADYCGCGYGAKVTEALETYTRREGFYQLTIHSELTAQTFYENLGYQTYGSKYLEDG
                     EYCQSLVKTILKWEKNMDIAMLIAIVGGLLGCYLYLTKNNEPKD"
     gene            56542..57555
                     /gene="argF"
                     /locus_tag="VGY43_000208"
     CDS             56542..57555
                     /gene="argF"
                     /locus_tag="VGY43_000208"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEQ4301431.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            57725..59218
                     /locus_tag="VGY43_000209"
     CDS             57725..59218
                     /locus_tag="VGY43_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEQ4301432.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGFFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            59235..60566
                     /locus_tag="VGY43_000210"
     CDS             59235..60566
                     /locus_tag="VGY43_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEQ4301433.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFHTYIDPEGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTDPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGCDKLSLEIGQAYNVVPARASYKG
                     NKLEALQKELDKLGFEYVVKEGELTVYGLAQHAKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            60586..61536
                     /gene="arcC"
                     /locus_tag="VGY43_000211"
     CDS             60586..61536
                     /gene="arcC"
                     /locus_tag="VGY43_000211"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEQ4301434.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALMSTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQTKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            61849..62841
                     /locus_tag="VGY43_000212"
     CDS             61849..62841
                     /locus_tag="VGY43_000212"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEQ4301435.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKKHIGEVQTSVWPQEVRDSYDNIL"
     gene            62964..63503
                     /gene="rsmD"
                     /locus_tag="VGY43_000213"
     CDS             62964..63503
                     /gene="rsmD"
                     /locus_tag="VGY43_000213"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEQ4301436.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            63493..63984
                     /gene="coaD"
                     /locus_tag="VGY43_000214"
     CDS             63493..63984
                     /gene="coaD"
                     /locus_tag="VGY43_000214"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEQ4301437.1"
                     /translation="MLTKIGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            63971..65008
                     /locus_tag="VGY43_000215"
     CDS             63971..65008
                     /locus_tag="VGY43_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEQ4301438.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDADFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPIT
                     TVQEALVYLRK"
     gene            65422..66399
                     /locus_tag="VGY43_000216"
     CDS             65422..66399
                     /locus_tag="VGY43_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ4301439.1"
                     /translation="MVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARHKIKAAIAKLH
                     YTPNVLAQSLKTKKNQLVGLLLPDISNPFFPRLARGAEEYLKEKGYRVMLGNISDSEA
                     LEEEYVHVLLQSNAAGIITTHDFTKRYPTLAIPVVVVDRVDQETQYGVFSDNRAGGLL
                     AAQTVWQAGAKEVLLIRGPLDNAENINERFEASFSYLQKQDVTMYVCDSQNFDFESIQ
                     LEASYNLKCYPTIDSIIAPSDIHAIAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYP
                     SLSTIHQSSYLMGRYAAELVYTIASQLTVKANRIKLPVHYVERETIRKR"
     gene            66823..67467
                     /locus_tag="VGY43_000217"
     CDS             66823..67467
                     /locus_tag="VGY43_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HEQ4301440.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPAIPK
                     SKSKRVSKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            67471..68550
                     /gene="rlmN"
                     /locus_tag="VGY43_000218"
     CDS             67471..68550
                     /gene="rlmN"
                     /locus_tag="VGY43_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEQ4301441.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVS
                     LHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(68632..69258)
                     /locus_tag="VGY43_000219"
     CDS             complement(68632..69258)
                     /locus_tag="VGY43_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEQ4301442.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQLQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLTSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            69486..70013
                     /locus_tag="VGY43_000220"
     CDS             69486..70013
                     /locus_tag="VGY43_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEQ4301443.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            70155..70358
                     /locus_tag="VGY43_000221"
     CDS             70155..70358
                     /locus_tag="VGY43_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEQ4301444.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            70363..71334
                     /locus_tag="VGY43_000222"
     CDS             70363..71334
                     /locus_tag="VGY43_000222"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEQ4301445.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIIASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFAYSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            71344..71733
                     /locus_tag="VGY43_000223"
     CDS             71344..71733
                     /locus_tag="VGY43_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEQ4301446.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRTKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMHPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            71916..>73755
                     /gene="typA"
                     /locus_tag="VGY43_000224"
     CDS             71916..>73755
                     /gene="typA"
                     /locus_tag="VGY43_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEQ4301447.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
BASE COUNT        22521 a        13390 c        15835 g        22009 t
ORIGIN      
        1 cgaatcccgt acggactata gctatttagt aactttggtt aaagtaatcg aactaacttg
       61 gttgattgta ttttaatgat aaaaagctta aatttgttat acaacaaatt taagcttttt
      121 attgtttctt tttaattgca gattgaggtt taaaagacac tttacaatgt tctcaagtca
      181 tgtgttgttg taggttgtat gcacatatta caaatcccat tatagaagaa attgtttaat
      241 taatggatag taatggatgg tatggagatc ttaatgtggt tttaatggta attttagcag
      301 ttatagtaag acaaaaggtg acttggaaaa gcttatgcag acgattctta actcccacaa
      361 tatcttctgt cagattttat tagacttctt cttggacatg agttggttta cgatttagta
      421 caaattgaga ttgagctagt gtttcagttt caattttgtc tgttttacga acgtgcaggc
      481 tattcaattg cttcttagct tctaaaggat taaaccgagt ataagcgtag ccattatctg
      541 cgaaaaaacc tgaagacgac gagaatagac attaatcgct ttaaggataa tctcagggtt
      601 atggacggtt ttcaagtttc caagaagatg attgaggccg atggtatcgt tttgtcttga
      661 atgattcctt attttagtgg tttcattttc aatacacgac gtcaagcgtc ctacatactt
      721 tgataaaatt ctacctaaaa gaggtgtctt gtcagttttg attacaacat caagtgccaa
      781 aagactttgc gacttaacaa gaaacttcta ctttaacgca aagaaaaagt agtgagtact
      841 ctctttcgtc ggagatttcc tcgctactaa acttagtatt ttttgatact ttccttaggt
      901 agtgcttaag gcagcgactt tctttggaat tccatgcctt atttttgaga tcctaggctc
      961 aaaaatgcca agtggcgtca acattaacat tgacgccact tttaccacaa ggaaaaacat
     1021 ctgttttggc tcactccaca cgcagaaata ggaaattgga tgtcaaatca gcagagctgt
     1081 tcatgctttt tgagcctaaa actgagtttg tctgcgttct gagcactcct tgggagtgct
     1141 ggacaactct taacgattct tcagttcaag ataacgtttg taccaaatag tgatataggc
     1201 cttggaaaat ggtccttttt catgattaat ccaatcaacc aatattttga cattttcttt
     1261 taggataaag tccatatcgg ctgaatactg catctctttt ttatgaatct cgtattcatc
     1321 aacatcaagt aatctctttt caccatccgc aaagactttg acatctaaat cgtaatcaat
     1381 gtatttaagg gcctcagtgt ccatcatgta tggactagct aagttacagt aataagagac
     1441 gccattatct cgaatcatgg ctataatgtt aaaccagtat tttttatgaa agtaaacgat
     1501 tgcaggttcg cgggtcaccc atcgtctacc gtcactttct gtgacaagag tgtgatcatt
     1561 aactccaatg agggcatttt cagttgtttt tagtaccata gtatcgcgcc aagtacggtg
     1621 caaactacca tcatgcttat aactttgaat tgtaataaag tcgccttctt taggtaattt
     1681 catgccttac caactttcta caattaaact tatcctctat agtctatcat aaatgtgtga
     1741 aaaaatcact tcttttgtca gtctataaat aatttcttaa cttgcaatta atatcgtcgc
     1801 tgttgtagcc ttttcggtag agagcctgat agagcttttg ctttaaggta taaccatcat
     1861 atttgcgact gagtttacga tattgtttgt ctaattcttt gtcaagaaga tcttctattt
     1921 cttgattatc ttggtcaaaa ttaaggtgat tgaggctatg tttagctaga tcgtatgaaa
     1981 agcctttggt cagtaatgct tgggtgattt tatctttcaa ggcttttggt ggcaattttt
     2041 cttgatattt gtcaaagagt ttttggctta ctttttgagc gagttggcta aagtcagttt
     2101 gagataagat aggatcaatg tcatgacttg caatgccttt ttgtaataat ttttgtttta
     2161 agacttgggg acctttatca ccatttaact gattttggcg aatgtaggta tcagccaatt
     2221 tggtgtcgtc tatccattgt tcttcttgga gttgagtgat gatgtcagca ataatgtgtt
     2281 cttcaatctc atgcttgcgc aggtaatcag caacttgctt gttgctgcgt tgttgaaagg
     2341 aaagaaaata aagggctaaa tttttgccgt aggacagttg ggcaaaatgt ttcatgtctt
     2401 caagctgatc attgtcaagg actttatctt tactcaacat aaaccgaaca atagtatctt
     2461 ctgttacata aagggattcg tcattatcca attcgataag gtagaggcgt tttttctttt
     2521 caattttagt gattttcata ctttgattat atcaaaaatg gtaaaataga agatgaaaat
     2581 actgctaaaa atgtgttgct tgtgaatgct tttggtggtg agattaggat attagaggaa
     2641 ctaaggggaa gagatggtcg taaaggttaa acagaaaatt cctttaaaaa ttaagcgaat
     2701 gggaattaac ggtgagggga ttggttttta tcagaaaact ttggtatttg tccctggtgc
     2761 tttaaaggga gaagatattt tttgccaaat cacggcggtt aaacggaatt ttgcagaggc
     2821 caagctgtta acggtaaaca aggcttctaa gaatcgtgtc aaaccagctt gttctgttta
     2881 tgaaacttgt ggtggttgcc aaatcatgca tctagcctat cctaaacagc tagatttcaa
     2941 agatgatgtg attaggcagg cccttaaaaa gttcaaacca actggctatg aacaatttga
     3001 gattagaccg actttaggaa tgaaaaagcc agatcactat cgggccaaat tgcagtttca
     3061 gttgcgatca tttggcggga cggtcaaggc tggtttattt tcccagggaa gtcatcgctt
     3121 ggttcctatt gacaattgct tggtacagga tcaactaacg caagatatta tcaataagat
     3181 tacgcagtta gtggacaagt acaagttgcc catttacaat gagcgcaaga ttgctgggat
     3241 tcggacgata atggttcgta aggcacaggc tagtgatcag gtacagatta ttgttgtgag
     3301 tagcaaagaa gttcggttag cgaatttcat tggcgaattg actaaggcat ttcctcaggt
     3361 taaaacggtt gccttgaata gtaatcgttc taaatcgagt gagatttatg gggacgaaac
     3421 ggaaattcta tggggacaag aggcgattca tgaagaagtt ttagattatg gatttgcgtt
     3481 atcaccgaga gctttttacc aacttaatcc acagcagaca gaagttttgt atggtgaggt
     3541 ggtgaaggcc ttggatgtag ggagcaaaga tcatattatt gatgcctatt gtggggttgg
     3601 ctcgattggc tttgcttttg cagggaaggt caagtctgtg cgggggatgg atattatccc
     3661 agaagcgatt gaggatgcac aaaaaaatgc caaagccatg ggttttgata acgcttacta
     3721 tgaggcaggg aaggcagagg atattattcc taaatggtat aaacaaggtt accgcgcgga
     3781 tgccatcatt gtggacccac caagaactgg tttagatgat aaattattaa aaacgattct
     3841 tcattaccag cctaaacaga tggtttatgt gtcttgtaat acctccactt tggcccgcga
     3901 tttggtgcag ctaacaaagg tttatgatgt tcactatatc caaagtgtag acatgttccc
     3961 ccatacagct aggaccgagg ctgtcgtgaa gttacaaaaa cgtgtatgat tgagtggcaa
     4021 taacaactca agttttataa gctcaggtaa tgggtttgag caatagcttg acatagtagg
     4081 gatgtcaaaa acggtttact aaggatagtc atattattga taactctatg tttattttag
     4141 aaacattcat ggttaaaaaa gtttgttagt ttgtcactaa gtagggttta tttgaagagc
     4201 aagtacacac agacaatatt agggtaattg gttgttgaaa aaaagctgtt ttttgctata
     4261 aattagaaaa ctgagtggtc aggaggttac attaccagaa gttattttag tatgctaata
     4321 tgaacgatga tatagaggat ttatcctgat ttaatctttt aagctgtaag aaacctttgc
     4381 aaaaactgta ggctgtgtga gtctttatgt gttagatatt aaagataaat gcaacacttt
     4441 tttataatga gatcaacaac tgataaatct aagttgataa ccagtaaaat gatcggaatg
     4501 tagaaaagtt acttaatcaa gcttttcgta atttaactgt tagaatgaca gaacttatga
     4561 taaaataaag aatatgatta aaatgaaaaa gctcagttta tctattacgg agttcgaaat
     4621 gaaaagaaaa tcgagatgtg ataacatatt ttgaacgaga aggagaagga taaatgttag
     4681 aagattttct tcaattttta ggatttatat ttttagatat tattgaaatt atgttaacgt
     4741 taaagctttt tagctttgta agtgcaattc cgcttcgcct gaaaaatatt ttttatttat
     4801 cacttagtat ggttttgttt caagtagttt tttgggcttt ctttccagac catttcatcc
     4861 ttgatgttgt gatgttggct cagtttcttt tctttgcgct tatagcccta tactatggta
     4921 aatcaataaa agctaagttt ttaatgtttt atgccttttt tccactagtg tctattagtt
     4981 tggttaagcg atttattgta ttttttgtta tgccattatt tggtatgcct tattcagttg
     5041 ttaaacataa tacactactg atttacagca ttacttgctt tagtattttt ttgatttatc
     5101 gctgcattca agtttttcat ttcgattttt caacctggcg ccaatatttt caatcacata
     5161 gagctagtaa actattagtg tttactaact cttcgatggc tctatattac ttgtgtgtcc
     5221 aagggataga tgtgatgtcg ccttctttat caggacttgc tacaacgact gctcgttcaa
     5281 tcatagtgct cttttatttc attttgtttc ttactttatt aattcattta gagcgttatg
     5341 taaaacaaaa ctctattgag gcaattgtgc aacaaaaaga atatcgtgag ctgattaatt
     5401 atagtcagca ccttggattg ctgtatcaag atattcaaga gcttaggcag ctattaacta
     5461 ccgtgtccag tcgtcttaag attggaatcg aacaaaatga tatctctatt gtgagactta
     5521 cttatgaagg tatcttgaat gctgaaaaga ataatgctaa agatgacaga cttgatttaa
     5581 cttgtttaga taaattacaa gttgaagcaa tcagacatat tgttttagct aaattaattg
     5641 aggcaaaaaa taagaagctt aaggttgagg tatcgatccc taattgtatt gcaacgtttt
     5701 ttctagaagt agtagatctc actaagctat tgtcattttt gttagataat gctatagaaa
     5761 tgagtttgga gacaaagcaa ccttgcttat caatagcatt tctggatcaa aaccataaac
     5821 ttgtcatagt cattcaaagc agtactaaac aaggacaaga tgatagtcaa agcgtgtttg
     5881 ctataccggc tttgaaaaaa agagatgact ggcaatttga cttaaggaat gtcacgacca
     5941 ttttaaatcg ttatgactat ctcacaatta gctcgcagat tcatgatggc attttaaccc
     6001 agttaataga aatagctaag cctgactgat gttaaaggta tgaataatca ctcaaaatca
     6061 acttaagagt ctgagacaat agtcccagac tctttttgaa tatgttaatc tattactaat
     6121 gataatagtt tattgtttct tccaagctag agttaaaatt tccgctttgc caagttggct
     6181 gggtgtgctt tgcttgctgt ctttttctaa caaattagtg accttggcat tgtagtttgg
     6241 caggcttagg ctaaagtcac aagttttatc gtttgagaga ttatagctgc gcgtgataag
     6301 ggcattgtct gctaagcgac gtttgaaagc cgttagagcg acttgatcgt ctgccccagt
     6361 gacatagcta tgctctgctc ttaagcttcc cttatgatgg ctggtttgtt cgactaggat
     6421 aggaacttgg ccttcttgtg cccgccaata gctggcaaat tgtgtttgct tagtgatgct
     6481 ttcaaaacta taagataggc tgtgtttgcc gaggcattgg gcttcaggag tagggaaata
     6541 cccccagtcg cccatttcac caacagaacg taagagagtg atggcaatgg tgttggtatc
     6601 tggtaagatc tcatattcgt tgaggccgta gttaccaata gtgaccccct tttcaccatc
     6661 aaagagactc acaaagcatt cttggtgctg tgggttactt ggattcttcc aaaaggcagc
     6721 atttggatga tttggacgtt tgacagtttc aaaaatactg tcagctaggt gatggtctgt
     6781 cttaaggtgc gttgggaata agacgcgcaa gcgatgatta gtcatttggt tatcaaaact
     6841 tgtggtgaat tggaggcgag gattgttttt ctccatgcgg ataagggttg ttaaggtcag
     6901 ttcagctttt tcttgtgaac gtcctgattg gcgttccgtg atgtcaatga cagcctccat
     6961 ttcagcctgt aagagcttat ctgcggagac aggaatggca aaggtttgct ggatttcaag
     7021 ttcagcaact tgagcggtgt tgctaatgat gttaagcttg gtggtccctt ggtctgcata
     7081 gaaaggttgg tcatgatttg gttggcggga aatgtattca tttccaatat cgccacaatc
     7141 ttcaaaccgc aacaggtctt gatagattag tccagattgt ttatcggtga tggttagacg
     7201 accatcggtt tgtatcataa cttttagaaa ctcattttca aggcactgat tactatcgtc
     7261 gtagagtgga accgttgctg aaggagctgt ctcgtttcct agttgtaatg ctaaggcttt
     7321 ccaagacatg gcagggagag ttattggtag ccgtaatctc actttgatgg cgaaataagg
     7381 ttctcggaag gttctcttgg acaaatcgta gtcaaaggcg atgcttgtgt ccaaaatgtc
     7441 tgcttctgag atagtgtttc ctgatacatc aatgacttgg aaagattggg agagttctgc
     7501 caaatactct tgagcttctt ggtaaacctc tttaggaaag cgttggccaa aataatattt
     7561 tttccaggtc agggtgagct cagtaacact tgttttggaa tggccactgg tattaaataa
     7621 gaggaaaggt tggctatctg ttggaaagtc actggtatca atggcgtcag caatttgctt
     7681 agcagcttct tttgctaaat aatgtccgac ttcataggct ttttcaaagc gcgtcatcat
     7741 ttcccgatga acgctatcaa cactacaacc acagatagaa tcatgagggt gattttgcat
     7801 gagggttttc caagcgtaac gcagttggtc gtgagggtag gtacctgtta catcataagc
     7861 cattgttgct aagggttcgg tgatgttttc gagttggcga gagactctgg tattagcctg
     7921 tttgaggtaa atgcgagcag aagctgtgtt agttagggta taccagccat cggtttcttg
     7981 actggtaatc tctccttgga cggttgaaag attctctggt aaatcatctg cgagatcagc
     8041 caagtaatct tcaaagcagg aatgcacaaa ttcgtagtca ggatagagtt ggttggctaa
     8101 ggcgattgcc ttggtgacat caagttgtac gggttgatga tcacacccgt tcatcatcag
     8161 aaggtgcttg gttgaggcaa agcgttcagc gtcagcaagt tttttatccc aaaaaagacg
     8221 cgcctcagct tctgttgtcg ggatctcatt gccattgctg taccagttgg cgaaaaggag
     8281 tccaagaata tggctgtcat ctggtccttg ccaactgatt tcagagaatt gggagctgta
     8341 tttttcacgg gtatccacct gattgttaaa tccagttgga cgaatgccac gaccaaaggc
     8401 agcagcttgt aggccggctt ttaacatcag ctgtggtgtt tgtcccatat ttccaaaggt
     8461 atcaggaaaa taaccaagtg gcacactagc gccccatctg tcacaatctt ccttaccaat
     8521 cagtatattg cgcacattgg actcgctgct ggtcaaaaaa tcgtcctgta agatatagaa
     8581 aggtccgata cggagttttc ccgaagcaat ggcttgtcta atctcaggtt ctcgttcggg
     8641 gcgtactttt aaataatcat ctaggataat ggtttgccca tccaaatgaa aactatgaaa
     8701 atcaggatcc gtttgaaaaa cttctaacag gtcatctatt aagttaatca gacgcatgtg
     8761 gtgttgttcg taagccatgt accactcgcg atcccagtga ctgtgtgaaa taatatgtac
     8821 ttttttagtt gccatagtgg cctcactttc taaggagcaa tactaaagcc cagatagtca
     8881 agaagtagtt cacagaacat catgttagcc caagagaacc actcacgagt gtattgataa
     8941 ggatcattga catcgaaacc ctcgtgcatt aagtgggtac cagcatctgt tgccacaagc
     9001 aaatcaagca tctctttttt actgtcttgg tcaagagcgg tcaatccttg taagacaagg
     9061 gcgatatgcc agatataatt ttctggtgta tgggaagaac cgatgcccgc tgctgcattt
     9121 ccctgataat aataagggtt ttcttggcta agaatggtgc ggcgcgttgc caaatagata
     9181 gggtcatctt tagcgcaaaa accaaggtaa ggtgcagcaa ggaggcttgg aatattagca
     9241 tcatccatga tggaaaactg tcccagacca tccacttcat aagcgtaaat ggtttctccc
     9301 ttgctgtttt gaacaagggc atggtctgca atacccgatt gaatagcttc tttcagctgc
     9361 ttggcacgag tagctactgg ttcattgtga aaaaggttgt tatataaatc ttctagatag
     9421 gaaagcacaa ccactgcaaa catatttgaa ggaatgaggt aaccatattg acaagcatca
     9481 tcacttggtc taaagcctga ccaggtcatc cctgttggtg cgacaggact tccttttcca
     9541 gcatgtgtta gggtatcttc tttgcgccaa gtatcgcgtt caaacaagta aggagactgg
     9601 gcgtggtctt gctcaactgt ccataggtca agaatgagtt ctaccccacg atgaaaatcg
     9661 tcattaaact gatcggtgct tcctgtttca cgatagagca agtaagctag ctgaataggg
     9721 tagcagaggg aatcaatctc atatttgcgt tcccaaatcc aagggttcat ttgggtacga
     9781 tctgtttggt gtccttttcc gttagcttct tcgttgaagg cattggcata gggatcgata
     9841 caaatgtagc ggaattggcg tttgaccaaa ccggcaataa tctttctaat ttcttcatct
     9901 tccttggcga ggaagaggta aggtttcatt tgcgcagtgg aatcacgtaa ccacatggca
     9961 ggaatatctc ctgtcaagag aaagctagtg ccatcttcgt aggtttttag ggttgtctct
    10021 aaggtattgg taaagctggt tttgaaatta agagcccaat cagggtgttg gtctccacaa
    10081 aggctttcca ccttggccat aaattggctg acgctagttg ggattggtcg tgtcatatca
    10141 tatcctccaa aaagatatat catttatctt cggtttcatt ataaatgata agttaaactt
    10201 tgtctataag tttttgaaaa ggtttacaac tcttttttga catgctatac tgataacggg
    10261 agtaaagaat gacaaaatta ttatacaaaa agatatatca tttcattaaa gagcagatag
    10321 catcaggtcg tttgcaaatt ggtgaccgcc tacctactga aaaagaattg tcagaacagt
    10381 tctcggttag ccgtattact tctaagcgag cgcttgtaga actggagcaa gaaggcttga
    10441 ttacgagaag tcgtgggaaa ggaagcttcg tagctgaaaa gcaagtgacg tcccctgaag
    10501 cgaataagga tttattgttg attcttcctt ttgcttctga ttatgaattg ggagattatg
    10561 ctaagggaat tatgacctcc attgctgaaa caggttaccg tctcatggtt caattggcca
    10621 gtacagtaag gttagacacc ctgtcagact atgctgggat tatttattat cctgaagatg
    10681 tcaatcacag tattgatttc ctgttttact gcgaccatca tcacattcct ctagtcttgt
    10741 tggataaatc tctagatctt tttcagtttc cgtctgttgt agcggataat aaaggcggtg
    10801 cctgtcaatt gactcagcac ttgattgagc aaggctgtga ccagattagt tttgtggcaa
    10861 caggctcttt tggagaagta tcatccgtta gagaccgtta tttgggttac ttagcggcaa
    10921 tggcagaatc atctctaaaa tcccattatt ttcctaagac agagactgaa acaacagatg
    10981 cttatttgga ccgtttggtg aaaaccttat cggaaacgac agccactaaa agggggcttg
    11041 tcgtggaaaa cgattggttg gctattcagc tgattcaaaa aatcacacag gtaggcttat
    11101 ctattcctga tcaagtcgct attgtaggct ttgataatag tcaagcctcc cgtttgttga
    11161 gtcccaaatt aagcacagca gctcaagatt tttaccaaat ggggcaagaa gcagctaaag
    11221 tcttgttgca gattattcat gagccagacc aagcagtggt gtcttgccag ttacctgttc
    11281 aagtatttat cagagaaagt agtcactaaa aaagacgtta ctagcatgag ctggttagct
    11341 caggtaaagg agaccagaaa tgaccattta tcacgcctta aaggattatc aagaagtcat
    11401 gacaagagga gactatcttg tctttgacac gccattgact tgccgattta ttggccgttt
    11461 tttccgcttt gaaaatcaaa aagccctgct ggcagaattg gcaacgtcaa agtattttca
    11521 gtggattgaa gaaggccaag cagaggtgac gatgaaacac ttttttaacc gtcagctggc
    11581 taaggatgcc tttaccctga aggtttcaga agataaggaa atcattattg aaagccaaaa
    11641 ccttagaggt tttcgttacg cccaagaagc tttgcttaaa gtcatgacct tcaaagggga
    11701 taaactttat ttgcccattg tttctgtcaa gcacagcccg tcatttccta tgcgggggat
    11761 aattgaaggc ttttatggaa caccgtggac acgagaggaa cgaatcgatt gcctacgttt
    11821 tattggaaat aaaaggatga atacttacat gtatgctccg aaagatgatg attaccagcg
    11881 aaaactgtgg cgcgatcttt atcctgagga ttgggtgact tatttcaaag agctacttgt
    11941 agtagccaag gaagaaggga ttgatttttg gtatatgatt agtccgggac ttgattttga
    12001 ttataccaag gaagctgact atcagttgct ctatcaaaaa ttgcaacaac ttctagcgtt
    12061 aggtgtttgt cattttgggc ttttgctgga tgatattgac taccaaattg tagatgctgt
    12121 tgagagacga ttcaaaaaga ctgcctatgc ccaggcccac ttggcaactg aggttcatca
    12181 ctttttaaac caacaacatg cggcgccaga attggtgatc tgtccgacag aatacgacaa
    12241 ccaccatgat tctatctatt tgcaagagct gtcagaaagg attcctaaag aagtcgcctt
    12301 tttctggaca ggcccaagca cgctagcgag tcaaatctcg caagcagata tcgaaaccat
    12361 ggcagcagta tatcagcggc ctatcattat ttgggacaat attcctgtta atgattatca
    12421 aaaagatcca gaacgtctct ttttaacccc ttttgctaat cgctcaccat ttttatgcca
    12481 atcagactat caggtcaagg ggattgtttc taaccctatg attagttggg aattatctaa
    12541 gctgaccttg acagacatga gccattatct gtgggatgct aaccgttatc agcctagtaa
    12601 ctcttggcta gaaaccttaa cagactatac aggagatgct gaattagcct tagctttaca
    12661 ggcatttgct tggcataatg gcaatcgtca tctgcacagg gaccttcctt ttgaagtgga
    12721 agaagctctc ctggctaagg atgtatcaac gttatcagct tgggtagatg aattggtaga
    12781 acgtgccaat acgttgagaa agctagataa gccagcgttt caacaagcta ttgttccttg
    12841 gtttgaacgt gtggccaaag accaagattt ttggcaggcc attttagagc aggggcctca
    12901 tttggaaaca ctctatgctg acttacaaga agataaacac cgtattggaa gtgacattcc
    12961 aagtcgctac tatcgcatct actatcaaca gcaagataaa ctaacagcta atcaaggtca
    13021 agttacccaa gcaagacctg aagattatgc ttagtcatac gagctagaaa ggaatgatat
    13081 gttagcattt ccaaaagagt tttggtgggg aggagccact tcaggccctc aaagtgaggg
    13141 gcgatttgct aaacagcacc gcaatctctt tgattattgg tatgaagagg agcctgactt
    13201 gttttacgat tacgtgggac ctgatacggc ttcggatgcc tatcatcaga ttgaatctga
    13261 tttggccttg ttagcttcac taggtcacaa ttcctaccgc acctccattc agtggacacg
    13321 tttgattgat gattttgagc aagcgacgat taatcctgat ggccttgctt attataatcg
    13381 agtgattgat gcttgcttgg ccaatggtat tcgtcctgtt attaatttgc atcattttga
    13441 cctgccaatt gccctctatc aagtctatgg tggctgggaa tcaaagcatg tcgtggactt
    13501 atttgtcgcc tttagcaagg tttgttttga gcagtttggt gatcgggtta aggattggtt
    13561 tgtccacaat gaacctatgg tcgttgtgga aggctcttat ctaatgcaat ttcattaccc
    13621 tgctatcgtg gatgggaaaa aagcagtcca ggtcgcctat aatctagccc tagccacagc
    13681 caaggttatt caagcttaca ggcgaggtcc agcagaactt agtgatgggc gtattggaac
    13741 cattctcaat ctgacgccag cctacccagc tagtcaatca gaagcggata cggctgctgc
    13801 gcattttgca gaactttgga acaatgactt gtttatggaa gctgctgttc atgggaaatt
    13861 cccagaagaa ttggttgcgg tattgaaaaa agatggggtt ctgtggcaat caacgccaga
    13921 agaaatggct cttattgctg agaatagagt ggattatttg ggattgaatt tttaccatcc
    13981 taagcgcgtg aaggctcctg atgccattcc agtgattagc ccatcttgga gtcctgaatg
    14041 gtattatgac ccctacctga tgcctggccg ccgcatgaac gtggataagg ggtgggagat
    14101 ctatcctgag gctgtctatg atattgccat caagatgcga gaccattacg acaatattcc
    14161 ttggttctta tctgaaaatg gtgtagggat ttcaggagaa gaccgttacc gtgatgaaac
    14221 tggtcagatt caagacgatt atcgcatcca atttttgaaa gaacatttaa cctatctcca
    14281 caaaggaata gaagcaggct cgaattgttt tggataccat gtatggacgc caattgatgg
    14341 ctggtcttgg ctcaatgcct ataaaaaccg ctatggcctt gtggaaaata atatccatac
    14401 ccaagtgcga cgacctaaag cttcagctta ttggtttaaa aaagtagcta ctcataaccg
    14461 cttgatttca ttagaagtaa tggaggagtt tggaggctct gcttctcacc tcagtgattg
    14521 aacgtgtgaa cgtctccttt gagacaagtg aataatgatg ttaccaatga ttaaacaagg
    14581 gcctttttcc tcatgttaag aggatcgagg ctcttgtatt tctttggaag gtgttggtat
    14641 ttgccgaact agatataagc gttctgtctg gtttggcatc atctatccat cttgggtaat
    14701 ttggctcttc aattctttag agtatcttgg ctaaggatgc ttgtttttca tcttggtatt
    14761 ttaggatttt ctttcatatt tttggaccag ataaaagccc ctcatggttt ctagtgactg
    14821 tttgttatgt cactgtccac gataagggga ctatatgaga gagttattaa gtgaggcttt
    14881 gcttgttggc gataactagc atagcttcta atagctcgag tattaactga tgaccaatgc
    14941 ctttgacaga agcgtcagca acaacgacat caacaaaggg accaggcatc aggctgcgtt
    15001 catcagcaga gagtcattta ggcagaaagc cagtatcgtt gtagctaatc agcaatcctt
    15061 ttaggatgtc tttgtagatg tcagaggcga ttagggacaa taggggataa gagggattaa
    15121 gcggtccatg gttaggcctc cttgtgttct tggtaaaaat caatggcagc tccaagaaga
    15181 ttggcttcgt ttttaaagtg acaaatggct aattggggtc taaggtcgga gatttcgacg
    15241 gcttggtaga gtttgtctag ttcagcttca atcgctgaca gtagaaagtc agcttgggaa
    15301 acaccacccc cgattaaaat cagttgagga tcaaaggcgt gttgaatgtt aaaaataccg
    15361 atggctaaac tttggagaaa gacctgcctt tctttgagtg ctaggggatc tccttgttct
    15421 gtgagggcaa ggacagcttt gccagtataa tcttttccgt tattgacgat tgcactatag
    15481 cgcttggcca tattcacaac agtgcctaat tgactaaagg tttggtagcg gtcgttcatg
    15541 atcatgaaac caaattcgcc cccaaataag tgggcaccat ggtaaatctt gccatcaatg
    15601 accaagcttc ctccaactcc agtaccaata acgagcatgg ctaggctact agcgcctttt
    15661 cctgccccta aggtagcttc agctaaggcg gcacaattgg catcattttc gatagaaata
    15721 gggtaatgta gccgttcttc taaggcctct tgtattttaa aatggtgaat gtagggaata
    15781 gcgctggcgc cttcgataac ccccttttct ttattgactg ccccaggtga actgatggca
    15841 atacctgaga aatggtaagc agagtaacga gcaacttctt ggtcgagtaa ttggtaaaac
    15901 ttttccagac tagagggagt gggaaagctg ctttgctggc ttaattggcc attgtgacag
    15961 agggcaaatt taagggaagt gcctcctata tcaagacata acaagctcat gaggtgttct
    16021 cctttattga tagtagaata gacgatcatg tctcatctta gtatgacaga tttaagcaac
    16081 aatgaaaagg ctttctaagt gattctatac tttgtgttat catacctata atttgttgct
    16141 ttcaaataat gaaagcgctt gatatactgt aactataacg tgattaacac aaagggaggt
    16201 tgggaaatga caagacaaac caacaaaaag acatcctttt ggaaaaatgt gattaaatac
    16261 cgggccttat tattaatggt attaccaggt ttcatctggt tcatcttttt cttttatatt
    16321 ccagttttgg ccaatgtggt tgcttttaaa gattttcatt attcagcagg gggctttatg
    16381 gaaagtttga aggagagccc ttgggttggt ttggctaact tcaaatacct ctttgcttcc
    16441 aaagatgctt ggttgattac cagaaatacc atcgcttaca atgtgatttt cttactcttt
    16501 aatgttttct ttgcgattgc ttttgccatt atcatgagtg agttacgaaa taagcgaacg
    16561 gttaaggtct atcacaccat gtccttattg ccttatttct tatcatgggt ggttattgaa
    16621 tactttgttt ctgccttttt aaatacggat aaaggtttca ttaatcagct cttgactgga
    16681 agtggagcag atccaatcaa gtggtattcc aatcccactt ggtggccctt gattttactc
    16741 tttatgagtg tctggaaagg gctaggctac aatagcatta tctactatgc ttcagtcaaa
    16801 gggatttctg atacttatta tgaagctgct atggtggatg gtgcaagcaa atggcaacaa
    16861 attaggaaca tcaccattcc acaattattg ccaatgatgt ctatcctatt gatcattaat
    16921 attggtaata tctttaaatc tgatttcgga cttttctacg ttattcccaa aaattcaggc
    16981 ccactttatg acgtgaccag tgtgttagat acctatgtct acaatgcctt gactgctaca
    17041 ggagatattg ggatggcatc ggcagctagc ctttatcagt cagtagttgg gaccagcatc
    17101 ttgttagtca ccaatgcgat tgttcgtcgc atggaccctg atgcagcctt gttttaggag
    17161 gaaaacatgg agaaaaagaa aaaagtcgaa aaggttaatg ttagaacctt tgatcgaaaa
    17221 accaatgcta tctttaatat tctgattggt ctgtttgcca tctcttgtat cattcctttt
    17281 atcttcgtga ttattatttc cttcactgat gaaagttact tgattaatca tgggtatagt
    17341 ttttttccag atgtctggtc aactaaggct taccagtata tttttcaagg agccatgtcc
    17401 catagaatca tgaggtcatt tgggatatcc gtgtttatta cagtggtggg aacctttatt
    17461 aacacgacca tgacatcaac ctatgcttat gcgatttcaa gaccttattt cccatacaga
    17521 cgttttttta ctgtttatgc acttatcacc atgctctttg caccagggat ggttgctaat
    17581 tacttggtgg tcagcaatct ccttcatttg aaggatacgg tttgggcttt gattttacca
    17641 atggctctgg gcccatttgg catcttggtc atgagaacgt tctttaaaaa gacagttcca
    17701 gatagcatta ttgagtcggc tcgtatggat ggggctagtg aatggatgat ttttatgaaa
    17761 attgttctcc ctttggctgt tccagggatt gctaccatca gtttattttc tgccttaact
    17821 tattggaatg attggtttaa cgccttgctt tatgtgcaaa gtgaaaacct ctacccaatg
    17881 cagtacttac tgatgaaaat tcagagcaac ctacaggcct tggcacaaaa tgctggcatg
    17941 agtgcacaaa tggcagatag cttagcatcg ctgccaaaag aatcagttcg tatggctatc
    18001 gtggttattg caaccttgcc gattgccttg acttacccat tcttccaaaa gtactttgtc
    18061 ggtggtttga ccattggtgg ggtgaaggaa taggacttaa ggaactggtc acaagaccag
    18121 attttatcta atcattagta acaaaagaaa acatttttta ggaggcttca cttatgaaaa
    18181 agtggcaaaa aatcgtgtgt gtgactggaa ctgtgctttc agcgtctagt ttagcagcct
    18241 gcgaaagcaa gtcagcatca aaggatagtg atgtcaaatt attgatgtac caagttggtg
    18301 acaaacctga taacttcgat gaattgatga caattgctaa caagcgcatc aaagaaaaaa
    18361 caggtgcaac ggttgacctt caatacatcg gttgggggga ctgggatgat aaaatgagta
    18421 ccatcattgc ctctggtgaa aactacgaca ttgcttttgc caataattat gtggtcaatg
    18481 cacaaaaagg tgcttttgct gatttgacaa cgttaatgcc aaaatacgct aagaaaacgt
    18541 ataaaaactt agacccagcc tatattaaag gaaatactat tgacggtaaa ctctatgcct
    18601 tcccagtaga tgccaacgtt tatgcccaac agatgctttc tttcaataaa gaactagtgg
    18661 acaaatatgg ccttgacatt tcaaacatta agtcctatgc agatgctgaa aatgtcttga
    18721 aacaattcca cgaaaaagaa ccaaatacag cagcttttgc tattggtcaa gtctttagta
    18781 tgtcaggtga ctatgactac ccattaacca aaacccaacc ctttgctgtg aaaattgatg
    18841 aaggcaagcc aaccatcatt aatcagtatg aagatgagtc ctttaaaaac aatctccgct
    18901 tgatgcacaa atggtataaa gaaggtttga ttccaacaga tgcagcgacc aatacagaag
    18961 gttatcccct tgaaggaaac acttggttta tgcgtgaaga aacccaaggt cctatggact
    19021 atggcgatac tatcttgacc aatgctgcag gaaaagacat cgtgtctcgt ccattgacta
    19081 aaccgctaaa aaccacatca caagcacaaa tggcaaactt tgtggtatca agcgtatcta
    19141 aaaacaaaga aaaagcagtt gaagtccttt ctcttcttaa tagcgatccc gaattgttaa
    19201 atgggcttgt ttatggtgtc gaaggcaaag cttgggaaaa aattggcgac aagaaaatca
    19261 aactgctcga tggctatcaa ccaaaaatgc acatgggtgc ttggaatact ggtaacaata
    19321 aaatccttta cactcaagaa tctgttactg acgacatgat tgctaaacgt gaccaatcaa
    19381 tcaaggatgc taaagaatct ccaatccttg gtttcactgt tgacacaaaa gttatcaaaa
    19441 cggaattgtc aaatatttca aatgtcatga accgatataa agcaagtatc aatactggta
    19501 cagtggatcc tgacgaagcc cttccaaaac ttcttgcaga cctcaaaggt gctggttggg
    19561 acaaggtgca aaaagaagtt caaaaacaat tggacgactt tgtagctaaa gacaagtaag
    19621 gcattcattt tcttgattat aagttgaggg ctgggaaatc tcagctcttt tcttctgatg
    19681 agtggaaaaa acggatcatc aaataagtgg aagttataaa gggagaaaaa ttaatgtaaa
    19741 taatgttact actcttagta aagcggtttc caaaagccta taaagtgtgc tatattagaa
    19801 gagtctaaac tattaatcag agtaaaacta ataccagcat cttactgggg gtgctaaaac
    19861 tagtctcgta gctgctggtc cttgaaaccg ctataagtgt taacaagaaa aagaggacta
    19921 tcatatgaat ggcattgaaa aaacctgctt tttaatttgg aaaatgatcc aattgaccct
    19981 catttttcat ctcttgtcct tagctggact gattgtgttt ggggtggggc cagcctggca
    20041 aaccattgtc accctatttt taaaaacacc tcaagaagaa aaccactatt ctttgaaaag
    20101 ggctgttcaa ctttggaaat cttatttcaa agaagctaat ctaagatttg gtctttttgc
    20161 cctgactttc ctttttttaa cctttaattt gcattgggca gtacagtttc catccttgtt
    20221 ttggtttacc gtgtctttct tgattgtaat agccatggtt tggctaacca ttacctatct
    20281 ttacatggtt ttttatgcag tgagctatga gattaacctt tggaataata tgaaattagc
    20341 ctttatcagc gtctttttaa gtttcaaatc ctttttactc atgctgagtg ttttgctggg
    20401 aattacctta gtgacttggc aatacaaagg cctttatctc tttttaacct tcggagctct
    20461 agtcttttgc ttggactttg tcactaaggc taatcgtcga ctagtagatg gagtgattga
    20521 tgagtgttaa aacattggga aggtatgtga ctaaccactt taagcagggt tttttgatta
    20581 atcgactgat gaaattatat agcctgctaa ttgtaagttt tttcacttta gcagctattg
    20641 gcttgagcag ttattctatt agtagtactt ataaaagggt ggatgctgag gcgcagatgc
    20701 gactggagga gactctaggt agattgcagt tacaaaacga tattacccta cgggttttag
    20761 accagttggt tggccgttca gaagattacc ataacctcta tcaatatatg acgttaaccc
    20821 caaaccaata tttttcaaac gtttttgaag actgggaaaa aggaaaagac acggtcctat
    20881 tttctgaaga ggtgaggcgt ctttttgact tgtaccctga tgtgacttct atgaccctac
    20941 tgctagagga cagtagtgct tatctgtacg ccgatagggt cattaagacg ggtcgtttgc
    21001 tttatagcaa gcctgaaaaa gtaaccggaa atgttttagt tcgctccatt cgaaatccag
    21061 aatcaggaga tgtgacaggt cgtctttacc tgacctttga caaaccaccg actttggtag
    21121 agacacagca ggatcactat ttagctactt ttgcttttga ttactatggc cgcaaactct
    21181 tccatcaagg aggtcggaga tttcctcatt tagaggctga ggttaaaaag gctatcaagg
    21241 cagatcgggc agctgatctt agtaatctca gcaaggctta tcggatgcag tacaatcgct
    21301 cgggagacct cttagcttat gtggctgtca gaaaatccta tttattagcg gaagctgtca
    21361 ggacagtttt tgtgtatggc cttgtttctc tacttttagc ttggctgtta ttgcagttgc
    21421 tctttagggt tttccgaaat tatatccagc aggtttctga aattacggat actgttgaaa
    21481 tggttgcagc aggcgatttg tctttaacca tcgacaacag ccacatggaa ttggaactgt
    21541 atcatatctc agaagccatt aatcagatgt tggccagcat taaagcttat attgacgaag
    21601 tttatgtgtt agaggtagag caacgagatg cccaaatgag agctctgcag tctcaaatca
    21661 accctcattt tttatacaac acgttagagt atattcggat gtacgccctt agttgtcaac
    21721 aagaagaatt agcagatgtc atttatgcct ttgcgagtct gcttcgcaac aatattagcc
    21781 aagataagat gaccacctta aaagaagaac tggctttttg tgaaaaatac atttatctct
    21841 accaaatgcg gtatccagat agcttcgctt atcatgtaaa gattgatgag agtattgctg
    21901 acttagccat tcctaaattt gtcattcaac ctctcgttga aaattatttt gtacatggga
    21961 ttgattatag tcgcaatgac aatgcactaa gcatcaaggc attagatgag acggatcatc
    22021 tcttgattca ggtgcttgat aatggacgtg gtattagtca agagcgctta gcagatatgg
    22081 aaaaaaggct tcaagagcac caaacaacag gcaatagctc tattggtttg caaaatgttt
    22141 accttcgtct tttccatcat tttcgagaca gggtttcttg gtccatggct aaggagccaa
    22201 atggtggctt tattattcaa attaggatta gaaaggatgc ttgatgtata aggtactatt
    22261 agttgacgat gaatacatga ttttacaagg gctcaccatg attattgatt ggcaggcact
    22321 tggatttgaa gtggttcaaa cagcaagatc aggcaaggaa gccttagcct atttgactca
    22381 gtacccagtg gatgtcatga tttcagatgt taccatgcct ggaatgacag gactggattt
    22441 aatagaagca gctaaaacct atcatcctca gctacaaacc ttgattttat ctggttatca
    22501 agaattctcc tatgtgcaaa aggctatgga attagaaacc aaggggtatt tgctaaaacc
    22561 tgtggataag gcagaattac aggctaaaat gaaacaattt aaagactgct tggatgccca
    22621 gcaggcagaa tcaatccggc aagaagccta tcatgacagc cttttgaccc tttggcttac
    22681 agatgaattg agtgagaaag aatttcagca gctaagtcaa ggcttgccag cggctgcttt
    22741 aactggtttt acagtgctat atttggactg tcaagagtgg caagcagcca tcgatgctta
    22801 ttttgaacga gaaggtcagc ctttttacct caaaaaagaa gaagataaga aggtttatct
    22861 ggctgtccta cttggtaaaa ctgatcaagc caaggcattt acctatgatc tacaaaagcg
    22921 attctcaaga aacatgcatc aacttatttt gggagaaaca gttgatgact gggaaaatgt
    22981 ttatgaaagc tacaatcagg tgcttaagag cctcttttac aattgtgaag tgtcaccaat
    23041 tagagcaaaa gataagtcca aaattgaact accagagtcc cgtttgcagt tctttgcttt
    23101 taacaaggcg ttgatgattg gggacgaacc tacaatcttg tctaaattag aagctatttt
    23161 tgacgagatg aagaccttga acttttcacc agaggatgtg aagcatgttt cgttcttgtt
    23221 gttttctgac atttaccgtc aatttcccat tttagataaa atgacttatc tgtccatggt
    23281 aaaaactatt catgacagcc aatccattga tcgcattttg agggaactaa aaaaagtgtt
    23341 ggatgtcacc aatcagaaca attcccctga aaaacgctat tcagatttag ttagtgaaac
    23401 cattgattgc attcgcaagg aataccatca agaattaacc cttaaagcta tcgctgatag
    23461 gttacatgtc aatggggttt atttagggca atgctttaaa aatgaaaccg agcgtagttt
    23521 tacccagtac ttaaatcatg ttaggattca aaaagcgcaa cagttattgc tttacaccaa
    23581 ccaatccatc aatgaaattg cttatgaaac aggttacaat accaatcatt attttatcaa
    23641 gatgtttaaa aagttgaatg gtttatcgcc aaaagagttc agagatcgtt acaaggacaa
    23701 ttaccaagcc atcaagggcg atcagtaacg ttaaacagga gattgatatg acaccagata
    23761 gcaaggagca gacagtgact ggctaccaat accactatat tgatcaagaa ggaagaaagc
    23821 agccctttaa tcaaggctgg cgttttctta tggcagatgt ggcgtgtgct caggaccctt
    23881 cttttgatga ttcgaactgg caggtgattc atttaccaca tgatttcagt cttaagcagc
    23941 cttacacaag aaatgctgaa gctgaaagtg cttataaatt aggtggtgtc ggttggtatc
    24001 ggcattatct cgtgttagat gaggttttag ctggttgtca tgttgccatt acttttgagg
    24061 gttcctatat ggaaacggaa atttatgtta atgggcaatt cattggcaaa cacttaaatg
    24121 gctatcagga atttacctat gatatctctg atgtagtgac ttttggagct gaaaatcttc
    24181 tggctgtccg ggttgaaaac aaggttccca gttctcgttg gtattcaggc agtggtcttt
    24241 atcgtgaagt gagtttgtct gttcttcccc agcttcattt tgtggcagac caggtagcaa
    24301 tgaccttggc tgatactgct gtgcaggaga aagggcaaca gaaagttgat ttacgctttt
    24361 cccttaatca gtctattcag acttgccact accaattgag cctctgttta tgggaacaat
    24421 cacattgctc aaaagacaaa aaactccttt atcaagaaac agaagtgcct ctagctgatt
    24481 tggctttcca aagacagtat ggtcttacac tgtctttgga agaactccaa ttgtggtcac
    24541 cagataatcc tcacctctac gatttagaac tcactcttta ctatcaaggt caggtcattg
    24601 attgcttttg ccttgaaact ggttttcgtc agctgacttt tatggccaat caggggcttt
    24661 ttgtgaatgg cagagctgtc aaattaaagg gagtttgttt gcatcatgac caaggaggcc
    24721 taggagcttg tgcttacgaa gatgccctag ccagacaatt agtcctgttg aaagacatgg
    24781 gggctaatac cattcgtagc acccataacc caagtagtcc caaacttagg caactagcca
    24841 atcgtctcgg cttttttgtg attgaagaag cctttgacac ctggacctat gccaaaaatg
    24901 gaaacgttaa tgacttttca aactatttcc atcagactat cggaactgaa aatgcaaact
    24961 atcttcaaag agtgagatca cctgaaacga gctgggccca gtatagtatt gaggccatgg
    25021 tctggtctgc caagaatgac ccgtcagtgt tgatgtggtc gattggtaat gaattgatgg
    25081 aaggtttttc agccgatgtc agtcattacc cagagctgac aagacaaatg tgtcaatgga
    25141 ttgctgctat tgacacctca cgtcccatta cctttgggga caataaattg aaagaagctg
    25201 acttttgctg gcatgaggaa gtgtcgcaaa tggcaactct tcttagtcaa ttagaccatc
    25261 cccagggact cattgggtta aactatgcta gtggaaaaga ctatgataag cttcatgagg
    25321 agcactctga ttggctgttg tatggttctg aaacagcctc agccattacc agcagggctt
    25381 attataaaga gacaaaaaaa gttcttgact ccggttatca cctaacctct tatgatcatg
    25441 ctaaggttga ttggggtgcc ttcgctagcc aggcttggta tgataccatt acccgtgatt
    25501 ttgttgctgg cgaatgcgtt tggacaggct ttgattattt aggagaacct acaccctgga
    25561 acaagatcga cagcggtgtt gtaggccttt ggccttctcc taaaaatgcc tactttggca
    25621 ttttagacac ggcaggcttt ccaaaagata gctattattt ttaccaaagt cagtgggcgc
    25681 aggggcagac caccttgcac ctgttaccag tctggcagaa ggaccagctt tgtttcgatg
    25741 agcagggatt ggtggaggtt gtggtttata gcaatgctgc cagtgttcaa ctgatgtttg
    25801 aagatgagca gggcaacgta acagattatg gaaggaaggc atttcatact tatagcacgc
    25861 caacgggaca cacttatcag ctttaccaag gagctgacgc tgctaagaat cctcacgaga
    25921 atctttacct gacttggcga gtgccctatc aaaaaggttt gctaagggca gtggcctacg
    25981 acatttctgg taaaagcatt ccaaaaacca gtggacgttc tcaggttaga acctatggtt
    26041 cagtggcaaa gctatcttgg aaagcctttg aagcacctat tgacgctcct tgggaattgc
    26101 tttatctgga tttatcactc ttggatagcc gaggtgaatt ggtcagccat gctcaagatt
    26161 ggctaaaggt tcaagtagaa ggaccagccc atttgttggc tcttgataat gggaatccga
    26221 ctgaccacac cccttatcag gagcctctac gccaggcata tgggggaaaa ttattagcca
    26281 ttttagccct cactggagag gcgggacaca ttaaggtcac ggcaaaagtc tcgcagcaac
    26341 ttagcagtgt ttttcagaca caagtagcct gccgtgcccc caaagaacac ttagtgacac
    26401 tacctttaga gaaatatcag tttaaaaaga gccgactgac aagtcaacaa gaaattggtc
    26461 aatcttgtct aaagaccaca caattccttt ctgttttgga gaacaaagac acccagcaaa
    26521 aagcaggtaa ggttagcaca cctcacattc ttatcaccag ttaccagcac tatttatctc
    26581 tgcccttgca ggtttgttct caggcatttg attttaaaaa aggcgacgat atcttcttgc
    26641 ctcagtggct ccaagtcaaa gatgcccaag gttcttttgt gaaaaaagct tttccaatga
    26701 catggtacct aaaagagaaa atctttgcca agcctattct tgtcacgggc tatgtttctt
    26761 gttttgggca atcaataccg gttgaggcaa ggcttaacct agcacaagct agcaaaagac
    26821 ggcaccagga tctcagttta gtcgccaagc aatccctggc cacaagtcaa aaaaggctaa
    26881 cttattgcta ccaatatgat acggtgcaag ccataggagc cattagcttg caaaatcaca
    26941 cagacacatc tcttagtgtt tctgtggcaa tcagttatgg tagtcagagc tctattaagc
    27001 aagaaacctt gatgctagct gatagccact tgagccagtt agaagaggtt attttcttcg
    27061 atgatatttt gactgttttg tatctagtag tgacccttga agtcattgaa ggacctgacc
    27121 taactgaaga cagtattcaa attggccttt gggatttagc atgaagcata agtaaaagaa
    27181 gacttctttg gcaccaggtc tgatgaattt tgtaaaataa ggtataataa aaaacaaata
    27241 ggcgtccttt attacgtgaa aggcgccttt acaaggttga aatggaaagt gagatttcta
    27301 aatgtcagaa cgtttatcag gccacaccct gctggtctct ttgcttgcta ctcctattcg
    27361 tcatagtttg tctcccaaaa tgcacaatga agcctatgct aaactggggc tggattatgc
    27421 ctaccttgct tttgaagtag ggacagagca attagcagat gccgtgcaag ggattcgtgc
    27481 cttaggaatt cgtggctcca atgtgtctat gccaaataaa gaagctattt tacccttatt
    27541 ggatgacttg tccccagctg ctgagttggt cggtgcagtc aatacggttg tcaataagga
    27601 tggtaaagga catctcgtgg ggcatattac agacggcata ggagcgctca gagccttggc
    27661 tgacgaagga gtgtcggtaa agaacaaaat cattacccta gcaggagttg gtggggctgg
    27721 gaaagctatc gctgtccagc tcgcttttga cggcgccaaa gagattcgtt tgtttaaccg
    27781 acaagctaca cgtctaagta gcgttcaaaa gcttgtgaca aaactgaacc agctaacaag
    27841 gactaaagta acccttcaag acttggaaga tcagactgcc tttaaggagg ccatcaggga
    27901 atctcatcta tttattgatg ctacaagtgt aggaatgaag cctttagaaa atctaagttt
    27961 gattaccgac cccgagctca ttcgcccaga cttggtggtc tttgacatcg tgtacagccc
    28021 agcagaaacc aagttactag cctttgcccg tcaacatggc gcccaaaaag tcattaatgg
    28081 gctagggatg gtgctttatc aaggagcaga agcttttaaa ttaatcactg gtcaagacat
    28141 gccagttgac gctattaaac ctcttttagg tgatgagtaa ctcaaccttt tttaaagaac
    28201 tttttaagta agcttaatta tgatatatta ataagagatg gagcagtcat catgggctgc
    28261 taaaattctt tttgcgagag ctgtttttaa gagtaaaaag cttatttgaa gagccttatc
    28321 cctaacgtga tacaagtcat agttcctttg aggtctgcca gataacctac cgttttttta
    28381 gaaaagaagc tcttataaaa ggaaaagttc aatgaataaa ggagaatagc aatggtaaca
    28441 aaggaagttg ggcatgactt tttagcacgt ctaggaaaaa aacgcttaag acctggcggt
    28501 gttgaggcga caaactggtt gattgaacaa ggacaattct ctcaggattg tcacgtttta
    28561 gaggttgcct gcaatcgctg cacgacagca atagagttag ccaaaacctt cggttgtcag
    28621 attgatgccg ttgacttaaa ccccaaggtt gtcaaagaag cacaagaaag ggttactgtt
    28681 gaggggttaa cccgtcacat tacagtatcc caagccaatg ctttatcact accatttcca
    28741 gataaccatt ttgatattgt gattaatgaa gccatgttaa ccatgttgaa cgccaaagcc
    28801 aaggagaagg cactcaatga atattggcgt gtgttaaaac caggcgggcg acttttgaca
    28861 catgacgtag cttatgaaga tccaaaaaca agacaagtac ttgaagagtt acgtcaaacg
    28921 attcatgtca atgttgctcc cttgtcacta acaggttggc aagccttata tcaagaacac
    28981 ggtttttctc aagtgactta tcaccatggg aaaatgtctt tgatgacacc tcgtggaatg
    29041 atcaaggatg aaggtcttat gaacaccctg aacattatga gacgaggcct taagaaagag
    29101 aacagacaac agtttttaaa gatgcgtcgt ttttttacca gaacaggcaa aaatctctgc
    29161 tatattgctg taaaaagtgt aaaataaacc ttagaccaac ctgtccatac aactaaacag
    29221 accatagagg agttcgaaga tgtcttatat caataatatt gagcacgcga aggttcttga
    29281 tttgacgcaa gaagtaatga ttgagcaaga tcaaatgtta agtagaacac tagtccaaag
    29341 gcaagaccta ggaataacag ttttttcctt agataagggc caagaaattg ggcgacactc
    29401 atcaccagga gatgccatgg ttactatctt aagtggctta gcagaaatca ccattgatca
    29461 agagacctac cgggttgctg aaggtcaaac cattgtgatg ccagctgcta ttcctcatgc
    29521 cttatatgca gtagaagcct ttcaaatgct tttagtagta gtaaaaccgg aggcttaaca
    29581 tgattgaaaa tctctctcaa ctggtgcaat atcatgatca tcaggtggct agccgatcct
    29641 tgagccgtct actgggatta tctcaatcta ttgttttata tgccatggcc caaggagaaa
    29701 gcattagtca agagactagt ccaagagata aagtaatact tgttttagaa ggtcagctca
    29761 ttttcgattt agaggatcaa aaacaggtcc taactcaaga aagtctcata gccatacctg
    29821 cccaaaaagc ccatcattta gaagctaaaa ccgattgtaa actattacaa gtgcttttag
    29881 attaagggct tattgtcaac tgtattgggt ggcctatgga aaagcaaaag agaagatgac
    29941 gctcatcttc tctttttacg tattcaaagc gatgacaata cgaattttaa agcttggcct
    30001 tctcatctcc agattaatcc ctttagctta gtttatttta gaattcacta aaaaaacctt
    30061 aatgagtttc ctatctcctt atgggtttct cattaaggct ttttagacga aataattgaa
    30121 cgacaggcaa aagaaagatc tttttacgag tgataccgtt ctcctatagt tccataaatc
    30181 ctctttttga tgttgctgtt agttattctt agctaaaagt tatattgtta tcaagacttg
    30241 tcttgtagta acatgtttta ggagttccag gataccgtta ttctcttagc aagcttaact
    30301 agctagagtg gagtcactat ttataataaa ctgtcgagct tctcgacaaa ttggtgatcg
    30361 tctttgttaa tggctagggt ggtaaaaccg gtttctgtgg gtaatataaa gataatatgt
    30421 tgctcagaat tcttcttatc tgttttaaag acgtcaaaga gggatgtcgc agagacatca
    30481 gctctttcaa gtgttgttgg taactggtaa cgttcaaaaa cttgaaggag gctatccaag
    30541 tcctcttttg gcaagagtcc tttggaaaca gccagtttag catcaaccac cataccgata
    30601 gcaatggctt caccgtgatg gtaaaaatca tggtgacaga gcgattcaat cgcgtggccc
    30661 aaggtatgcc caaaatttaa agacatgcgc aaaccatttt caaattcatc ttgttcaaca
    30721 atccgttttt tattggaaat ggattggtaa atcagacgtt caagtccctg cttatcggtt
    30781 tctttttgaa aatcacgtaa ctgctgaaaa agcggtctat catgaatgaa gccgattttg
    30841 agcatctcac tgatgccgca ggagaattcc cgttgcggta aggtttccaa aaaggtggtt
    30901 gaaataatga cagcttctgg agggtaaatg ctgccaatca tattggttag acttttaaaa
    30961 tggactccaa ctttgccccc gatactgcta tccacctgac taagtaaagt cgttgggatt
    31021 tgaatgtagg gaataccacg gtaataggtt gcagcgacaa aaccacccag atccccaaca
    31081 acaccaccac caatagtaac aatcatatct tttttggaaa aattttcagc gatgagctgg
    31141 tcgtagatag cactgacacg tttcaaggat ttggattgac ctcccggggg gcagacatgg
    31201 acaaaagcgt tgtattgctg agcaaattct tcaaagagag tctgatacaa gtggtagacc
    31261 gtttgatcgg tgataaacaa gagtttacgc tgcttgcgct caccaaggca atctgctaag
    31321 gtttttaaaa catggtcggt aaacaggata tcataatcct tgacccgaga atggacatga
    31381 agtgtttgtg gcataagcac tcctttcatc agtactaggt aacagagata acgcagtgat
    31441 atttagagct taatcttgcc aaagttcctg ccccaactgt tctaattgct tataatcaat
    31501 ttgctgggca gcatctgaca gcgcatggtc gggatcagga tgaacctcca tcatgatgcc
    31561 attggcaccg acagccttcg ctatcttagc agcaggtaag agtaaatctc gtctgcctgt
    31621 cgaatgagac acgtccacaa taatcggtaa atctgtcttt tgttgaataa tagggactgc
    31681 cataatatca agcatatttc tagtctccac atcgtagcca cgaacgccac gttcgcataa
    31741 gataatgtta gattttccag tgtcttgtaa gtaggaaagg gcgcccaaat attcctcgat
    31801 agtagccatc aagcctcgtt taaacaaaat aggcttatcg atgtgtgaca agatttttaa
    31861 aaattcaaaa ttttgcatgt tgcgggcacc aacctgaatg acatcgagat agtcataggc
    31921 ttcttctaat tggcgctcgg acatgatttc actgaccgat agtaagccaa attcctgaca
    31981 aacctcatgc aagtaacgaa ttccttgcag gccaaggcct tgaaaagaag cagcagatgt
    32041 tcttggttta taggcgcctc ctctaaaata gttgtaacca agtttttttg cacttgaagc
    32101 tgctaatcta atgtgatcat aagattcaat ggaacaaggt ccaacaataa aattattctt
    32161 agaacaagtc ttattttgaa agtcagacat aatgtcaatc attcgtttga ttcctttact
    32221 aattctgtat ggcgtgctct atgggataac gtcttattta ggaatacaaa atctcgttgt
    32281 tatccatgaa gcacccttag cctgtgaaat gataccataa acaagatgaa atagcaagta
    32341 aaccctagat tgtctatgtt cttagtcatt tttattaaaa aaggcttgct agctataaaa
    32401 aaatactgcc ccaaatctta ttaggacagt attttttata gatgccacca ccgagaatcg
    32461 aactcggaac gaagcattac cattgcttta ttataccatt taactacagc ggctaccttt
    32521 ttataatact ataagttatt aattgatgca agcttttctt aaaaatattt ccttaattgt
    32581 ttatcatcaa aatgagagta ccagttatta ataacatggc acaagaggcc tgccttatgg
    32641 tataatggta aagatgattt cagaaagagg aagctaagca tgtcttatga aaaagaattt
    32701 ttaaaagatt ttgaagactg ggttaaaact cagattcaag tcaatcagct agccatggca
    32761 accagtcaag aagttgccca agaagatggc gatgaaaggg ctaaagatgc ctttattcgt
    32821 tatgaaagta agttagacgc ctacgaattt ttactaggta aatttgacaa ttataaaaat
    32881 ggtaaagcct ttcacgatat tccagatgag ttatttggag caaggcatta ttaaggacaa
    32941 ggagacacga aatagtggca aaacaaaaaa atcgtaaaaa agcattgaaa ttagaaatga
    33001 agcgtaatgg cttgttaaaa aaagcaggtc aagtttttga taaggcagtt gaaagtgttg
    33061 aaacagctgt ggataaaacc atttctgctg gtaaaaatct tgtggaaaaa ggcagccaaa
    33121 cggttggaaa cctgacagca agcaaggaaa gacttactct tgatgagttt gcagggcagc
    33181 cagttgtagc tggtatccgc tctgaccttg tggaaaccct atatgcagaa ggcatccatt
    33241 cagcgcaagc ttttaaggag tggacagaaa aagacctcct tgctcttaag ggcattggcc
    33301 cagcaacggt taaaaaattg gtcgaaaatg gcgcaagctt taaaaaatag tcatcttctc
    33361 gttgcttaat ggctataaat ttgttagaat attagcaatc agaggtgcat tgagttggtc
    33421 tgttacagag agcggtggtg ttgagaaatc cgcacagatg tcaaggctag tagctgagga
    33481 tcagaaatca gatatgaaaa gtagcagacc cattttatgg tttgaaacag tggtggtacc
    33541 gcggaaatcg taacacgaaa ttcgtccctg tctaggttat ctaggcaggg attatttggt
    33601 ttcatttgaa agaagatgat ggcttattgt taaaatgttg ttagaagtat ataatagaaa
    33661 aactttgccc aaagtggaaa cagaacggct gctattacgt caacgaaaag gggacaaggc
    33721 attgttccag aagcggcttc agctctgatt gaaattggtt ttaccttact tgatttgcat
    33781 aaaattgagc tgggttgcta cgactacaac aagcaaagtc aggcagtggc tcgcaaatta
    33841 ggctttacct tagaagccaa tgcccgtggc cgtaaggacg ttcaaggtcg ccgctgtggc
    33901 gacatgcgtt ttgggttact gagaagtgag tgggaggagc agaaacaaaa atgaacctta
    33961 tcatcattgg tgctcaagcg tcgggcaaga tgaccattgg gcaagaagtt gccaggcaga
    34021 caggcatgac tttgtttcat aatcacgatt ctattgactt tgttttacgg tttatgcctt
    34081 ggtctcaaga gagcactgcc ttgattgaac gtatccgttt tgcttttttt gaaacctttg
    34141 ctaagacagg tcaagacatg atttttacta ttgtaattga cttcaatgat ccaaatgatg
    34201 tagcaatgct tgaaaagatt caggctgttt ttcagtctta tgaccaagag gttctctttg
    34261 tcgaattaaa aacagatata gaggaacgtc ttaaacgcaa tcgcacagaa aatcgtctca
    34321 aacataaacc tcttaaacgc aacatcgagt ggtcagaaca agatattcaa tccacgatgg
    34381 catatgctgt ttttaatcca gaagaaccac ccaaaacgct cacgcattac caaaaaatca
    34441 ataataccca gctcaccgct gctgaaacag cgcagcttat tatccaaaaa atgactcata
    34501 tcaaggagaa ctaagatgac agaactatca cctaaataca atcctgccga ggttgaggca
    34561 ggtcgctatc aaaaatggct tgatgcagat gttttcaagc catcaggaga ccaaaaagca
    34621 aaaccgtatt ctatcgtgat tccaccgcca aatgtgactg gtaagttgca cttgggacat
    34681 gcttgggaca caacgcttca agatattatc attcgtcaaa aacgcatgca gggctttgat
    34741 acgctttggt tgccagggat ggatcatgca gggattgcga cacaggctaa agtagaggag
    34801 cgtctgcgcg agcaggggat ttctcgttac gaccttggtc gtgacaaatt cctagacaag
    34861 gtctgggagt ggaaagacga atatgccact acgattaaag agcagtgggg caaaatgggg
    34921 ctttctgtgg actacagccg tgagcgcttc acccttgatg agggcttgtc aaaagcagtt
    34981 cgcaaggttt ttgttgacct ctacaaaaaa ggctggattt accgtggtga attcatcatc
    35041 aactgggatc ctgctgccag aactgccctt tctgacatcg aggttatcca caaggatgtt
    35101 gagggagctt tctatcacat gaactatatg ttggaagatg gctcacgcgc ccttcaagtg
    35161 gcaacaacgc gaccagaaac catgtttgga gacgttgccg ttgccgtaaa tccagaagat
    35221 cctcgttaca aagatttgat tggcaaaaat gttattttac caatcgtgaa taaattgatt
    35281 ccaatcgtgg gtgacgagca tgccgatcct gaatttggga ctggagttgt gaaaatcacg
    35341 cctgcccatg atcctaacga cttcgaggtt ggtcagcgtc ataacttacc acaagtcaat
    35401 gtcatgaacg atgacggtac catgaatgag ttagctggcg actttgcagg catggaccgt
    35461 tttgaagctc gtcaagctac cgttgctaaa cttgaagaac ttggcgccct agtaaacatc
    35521 gaaaaacgtg ttcactcagt aggtcactca gaacgttcag gtgcagccgt tgagcctcgt
    35581 ctatccaccc aatggtttgt aaaaatggat gagcttgcta aacaagctat ggacaaccaa
    35641 gaaacagatg accgagtaga tttctaccca ccacgcttta atgatacctt ccttcaatgg
    35701 atggaaaatg tccatgactg ggtaatctcg cgtcagcttt ggtgggggca ccaaattcct
    35761 gcttggtaca atgcagaagg tgagatttac gttggcgaag aagcaccaga aggtgatggc
    35821 tggactcaag atgaagatgt tcttgacact tggttctcat ctgctttatg gccgttctca
    35881 actatggggt ggcctgacac agatgtagaa gatttcaaac gttatttccc aacctcaacc
    35941 ttagtaacag gttatgacat cattttcttc tgggtgtcac gtatgatttt ccaatcgctt
    36001 gaatttaccg ggcgtcagcc attccaaaat gtcctgattc acggtcttat tcgtgacgaa
    36061 gaaggacgca aaatgtctaa atcattgggg aacgggattg atccgatgga tgtcattgag
    36121 aaatacggtg ccgatagctt acgttggttc ctctcaaacg gctctgcccc aggacaagac
    36181 gtgcgtttct catacgaaaa aatggacgcc tcttggaatt tcattaataa aatttggaat
    36241 atttctcgct atatcctcat gaataacgaa gggttgacct tggaagaagc tgaaagtaat
    36301 gtggctaagg tagctgcctc agaagctgga aatgtgactg accagtggat tctccacaat
    36361 ctcaatgaaa caatcgctaa agttacggaa aactttgaca agtttgagtt tggtgtggca
    36421 ggacacattc tttacaactt tatctgggaa gaatttgcca actggtatgt ggaattgacc
    36481 aaggaagtac tgtatagcga caacgaagct gagaaagtta tcacgcgctc tgtccttctt
    36541 tatactttgg acaaaatttt acgtctcctt cacccaatca tgccatttgt aacagaagaa
    36601 atttacgctc aatatgccca aggttctatt gtgacggtgg actatcctgt ggttcgccca
    36661 gcttttgaaa atgaagctgc gcataaaggt gtggaaagtt tgaaagacct gattcgtgca
    36721 gttcgtaatg cgcgcgctga agttaacgtg gcaccatcaa aaccaatcac cattttggtg
    36781 aagacagcag atagtgagtt ggaagacttc ttcaccagca acgtgaacta catcaaacgt
    36841 ttcaccaatc ctgaaaaatt agaaatcagc tcagccattg ctgcgccaga gctggctatg
    36901 accagcatca tcacaggtgc tgaaatctac ttgccactag cagatttgct taacgtggaa
    36961 gaagaactcg ctcgcctaga taaagaactg gctaaatggc aaaaagaatt ggacatggtc
    37021 ggcaaaaaac tcggaaacga acgcttttta gccaacgcca aaccagaagt cgtccaaaaa
    37081 gaaaaagaca aacaagccga ctaccaagcc aaatacgacg caacccaaga acggattgca
    37141 gagatgaaga aaattaaatc atagtgttta gaacgcagtt gaaaaactgt gttcttttct
    37201 tactaataga gatattagat tgaagtttaa ttatgagaaa aacgctttct ttatttaaag
    37261 agttatgtta caatactatt acaatcatcg tacaaatagt gttattttga ggggcatatg
    37321 agaatgattt tagcacacta tgactgtaaa aaagataaaa agcaatcttt agatgagcat
    37381 ttatggcatg tggcctgttc tagtcgacag gaagcatcta taattggtca aggagatgtg
    37441 ctttttttaa ttggtcttta ccacgacctg ggcaaagctg atcgaacctt tcaagataaa
    37501 ttattaaata atccaaatcg gcatgttgat cactcttatg caggggcaaa atacttatgt
    37561 tctattattg ggcctcatct aaaaaaccga ggggttgata aaaatgagag aatgacattc
    37621 aacgaaatgg tggggtatgt catctctgct catcatggga tgtatgattt atgctactat
    37681 tttgacgatg ctgaatatta tggctttaat aagtttaaaa atcgtatcaa tagagactta
    37741 gatggttatc actatcatga agatattaaa gggtacgctc taaaattaga aaaaaattat
    37801 gtgattatgg ctacaaagat ttaagggagc ttattgataa agcttttgat aattaccaac
    37861 aatccatgtc ttccttaaac tggcaagata agagtgagtg ggattattat cagtcttgta
    37921 tggtgagact ttacttgtca ctcttaaaaa acgctgatat tttggacaca gtaaatgtct
    37981 atggccttaa gataagtcct atggataaaa cagagcgatc ctttctaaaa cactcctatt
    38041 tagcggccat tgaacaaaaa tatgctagct ttggacagcc aaacaatcag ttgaacacta
    38101 ttcggacaga aatcgctgag cgtgttaaag aaagaggtaa acgagattcc aaggggattt
    38161 atcgcttaga tttaccgaca ggagctggca agactaatct tagtatgcgt tatgcgtttc
    38221 accaattagt tcatcacgac aaatcaaggt tttttacata acgccctttc tttcggttct
    38281 tgagcaaaat gcttccgaaa ttagaaaagt tacaggtgac cttggcgttc tagaacacca
    38341 ttccaatgtg gtgaaacagg ctaatgaaga tgatgatgac aaggacagtt tattgtcagc
    38401 ttatcttagt gatagctggg acagtcaagt agtcttgact tctatggttc aatttttcca
    38461 aacacttttc aaaacaaaat cagctaatct gagacgtttt tcaagtttga ttaatagtgt
    38521 tgtgattcta gatgaagttc aatccctgcc tattgaagtc accactttgt ttaatttaac
    38581 gatgaatttt ttaaataaag ttatggatac aaccatcgtt ctttgcacag caacacaacc
    38641 tgcttatgat tcttcagaga ttgaccatcg tatctgttat ggagggaact tgggagaatt
    38701 agctgaaatc gttgagttaa cgattgaaga aaaacagatt ttttcaagga cagagcttag
    38761 aaaatttgat gatagtgatc agaaagttca cttgactgat gttattaacc ttattctagg
    38821 tgaggaaaac tcagttcttg ctatttttaa tacgaaaaaa acggttcata actgctatac
    38881 tatgctaaaa gacatgactg atagaccggt ctatcagctt tcgacaaata tgtgtgcgca
    38941 gcatagactt gacttgattg ctaagatcaa aacggagtta caaaataata tccctattat
    39001 ttgtattagc acgcaattaa ttgaagcagg tgtagatgtt gattttcatc gcgtcattcg
    39061 ttcctactca gggattgatt ctattattca ggctgctgga cggtgtaacc gagaaggcaa
    39121 acgagataaa gggcaagtca ctcttgtcaa tctgaccaat gaagaggaaa atatttctag
    39181 gctgacagaa ataaaagcta aaaaagaagc cacagaatct attcttcata agattgggtc
    39241 tccaattgat atcttaactt taaaccgtga cttttttgag tattattatg ccaataatca
    39301 gggactgatg gattatcctt tggaagacaa cctatcaatc tacgactatt taagccttaa
    39361 tatttatcag acggcaaata aaaagttcaa aggtaagtta aaacaagctt ttaaaacagc
    39421 aggagccaaa atgaacctca tcaataatga tatgatagga attctcgtac cttatggcga
    39481 agctgagaaa aaattggctt atttagaaga attgggtatg tctcactttt tatcagcaga
    39541 agattatcaa acgataaaat cattactaaa agagttacaa ccttttacgg ttaatgtccg
    39601 cgagaacgat cctctctttg agacaacaaa atcttatcta aatggtcaga ttctggtttt
    39661 gacgtcggag tattatgaca cggaaagagg agttaaatac gattcagcta gcttttactt
    39721 ctaactcaaa acgaaagcag attaacaaaa ggttgttaga ggaccttgtt aacctgccaa
    39781 tcatcattaa taattattat caatttagac tatttaataa aattagatta caaaaaaaca
    39841 gaaggaggaa agtagcttgt acagatctag agacttctac gtgagagtaa gtggtcagcg
    39901 agctcttttt acaaatccag ccacaaaagg gggatcggaa cggtcatcct attcggttcc
    39961 gactagacag gcactgaatg gtatcgttga tgccacctat tataagccga cctttactaa
    40021 tatcgtcaca gaggttaagg ttattaacca gattcaaacc gaattacagg gtgtcagggc
    40081 tctgttacat gattatagtg cagatttaag ttatgtatcc tatttgagtg atgttgttta
    40141 tctgatcaag tttcattttg tttggaatga agatagaaaa gatttgaact cagatagact
    40201 tccagctaaa catgaagcca ttatggagcg ttctattcgt aaagggggac gtcgagatgt
    40261 gtttttgggt acaagagaat gtttagggct tgtagatgat atcagccaag aagagtatga
    40321 gactactgtg tcgtattata atggtgtcaa tatcgacttg ggaatcatgt tccattcctt
    40381 tgcctatccg aaggacaaaa agacaccatt aaaatcatac tttacaaaga ctgtgatgaa
    40441 aaatggagtc attacgttta aagcacagtc tgaatgcgat attgttaaca cgctttctag
    40501 ttatgctttt aaagcaccag aggagataaa atcggttaac gatgaatgca tggagtatga
    40561 tgccatggag aaaggagaaa actgatggat ttttttactt ctctcttgaa gacttatgaa
    40621 aaagcagagc tagcagactt ggttgatcat caaaaaagaa ataatgagcc ggttttactg
    40681 ccgatttatc atacgagttt aaagtcaaat ggtaaaaata tcatttcagt gaaacttgac
    40741 aaagatggcc agtttcacaa ggcagaattt atggtagata agcaaatgat tatttttcct
    40801 gtaacggctg attctgttgc taggtcaggt agtcatcctg caccgcatcc tctagtcgat
    40861 aaatttgctt attatagtgc tgaaatgggg cagtcccagt atgattcttt tcataagcaa
    40921 ctgaataact ggattgatta ttgtgaggag ggtgacgtca agaggttttt aaccattgtt
    40981 cagcaattta ttttgaaacc agaatttctg acactgattc tcgattcttt aattggtcct
    41041 gattatcaac ataatcaatt aaaagtcaca ttttgtgatg ccactggaaa agaaaaatta
    41101 attgatttat cagcttgctt tttagaattt tcaattgatc agttccaggg ctttaaaaat
    41161 gaatcggttt cgacgtttaa agctttacac caatcctata tttcttttgt tgaagccaat
    41221 cgtgaaaatc tcggtatttg taatattagt ggacgagagg aacagcttac cgataagcat
    41281 agaggtttga tggggaatgc taaaatcatc tctgttagta ataaaagaga agcttataaa
    41341 ggacgtttta gagaacgcga agacgttttt agtgttggct atgaaacttc cgaaaagatt
    41401 catttaatgc tcaagtacct tttagaaaat aaaaatacca ttacttggtt agggtcttct
    41461 caatatttaa tcaactggtt tagtgatgat ttaacaaatg atagtcggtt ggatatcgta
    41521 tcaccaatct ttgatgacgg acttgaagaa gatgatgatg acgatacgcc tcctgttata
    41581 acattagcaa ctgaagacaa taaaagaatt ggtaaatcat tcatcaaggg acaaaaatta
    41641 tttgctaatg atgccactta ctacgttgct attttgaata aaaccagcaa tgggcggatt
    41701 gctttaaaat attttcgtca gcttcaagcg tcccaattac tcaccaatct taacaagtgg
    41761 caggaaacat acagttggga gtcgcgatct aagtttggga aaagtcgctt aagaacccct
    41821 actgttcatg acatccttaa tgtgtcctac ggggttgata gggatcgctt ccttgaatta
    41881 gataatgata acttcaaaag tgatcaaatt caaaagttag tggcaagttt gattgatggt
    41941 aaaccgatgc cacagtccat tgtcaaaaag ttaggtaaca atgttaaaga acgacatcgt
    42001 taccgtaagc actggtatca agttgagcag gtctgcttag caattttaca caaacaaaat
    42061 ggggaggaat tttcaccgat gctagatcat accaatcaaa atcgttccta tctttttgga
    42121 cgattattag caatttttga attaatcgag accttgcgtt atggcttgga tggaaacaat
    42181 aacgaccgta ttaccaatgc tgaacgttat tggacagcct atactggaca accaacaaaa
    42241 ttgatgatgt tattggaaaa taaaattaag ccttacgaag aaccattgaa attaaatcgt
    42301 cgtggcagtt ggatgaaatt agaaaaagaa aaagaagaga ttttagaact gttaaatcct
    42361 ctgttagaaa cagaaacaat ggaaaaaccc ttagattacc gctttatttt tgggtattat
    42421 gctgagaaaa actattacta tacaaaacaa aacacggaag taacagaaag tgaggagtaa
    42481 aaagatgttg gaacacaaaa ttgattttat ggtaactctt gaagtgaaag aagcaaatgc
    42541 aaatggtgat cccttaaatg gaaacatgcc tcgtacagat gccaaaggat atggtgtgat
    42601 gagtgatgtc tccattaaac gtaagattcg taatcgtttg caagatatgg ggaagtctat
    42661 ttttgtgcaa gctaatgagc gtattgaaga tgattttcgt tcactggaaa aacgcttttc
    42721 gcaacatttt acagctaaga cacctgacaa agaaattgaa gaaaaagcaa atgcattatg
    42781 gtttgatgtt cgtgcttttg gacaagtttt tacttatctg aaaaaatcaa ttggggtgcg
    42841 tggaccagtt tccatcagta tggctaagtc cttggagcca attgtcattt ccagccttca
    42901 aattacgcgt agtaccaatg gtatggaagc taagaataat agtggccgct cttctgatac
    42961 gatggggaca aaacattttg tagattatgg tgtgtatgta cttaaaggtt ctatcaatgc
    43021 ttattttgct gaaaagactg gtttttctca ggaagatgct gaggctatta aagaagtttt
    43081 ggttagcttg tttgaaaatg atgcgtcgtc tgcacgtccg gaaggctcta tgcgagtttg
    43141 tgaagtcttt tggtttacgc attcaagcaa attgggaaat gtttcaagtg cgcgtgtctt
    43201 tgacttgtta gagtataatc aatcaataga agaaaaaagc acttatgacg cttatcagat
    43261 tcatctaaat caagaaaaat tggctaaata tgaagcgaaa gggttaacgg ttgaaatcct
    43321 agaaggactc tagtatggtc tatgccgaag atgattattt aatgctatca ggtattcagc
    43381 atttccaatt ttgtaaacgt caatgggcgt tgatccatat tgagcaacaa tggcttgata
    43441 atgaagcgac agcgcatgga caggttttac atactaaagc agataaccct tacattaaag
    43501 aaaaacgaaa agagcttttg gtctcacgtg ctatgcccat ttcttctgca gaacttggac
    43561 tttcaggaat tatggatgtt gtggaatttt ataaagatga tcaaggtgtg tctttgaggg
    43621 gaaaacgtgg gaaatggtta ccaaaagttg tggaatacaa gcgcggaaaa cctaaaaaag
    43681 ataccagaga tattgtccag ttggtggctc agaccatgtg tttagaagaa acgctagact
    43741 gcgacattaa cgaaggttgt ctttattacc atagtgtcaa tcaaagagtg attgttccta
    43801 tgacatcagc tttgcgtcaa gaagtgaagg aattagccgc agagatgcat gaggtttatc
    43861 agagtcaaat gctacctaaa gcagcttatt ttaaaaactg tcagctttgt tctttagtcg
    43921 atatttgtaa gcccaggttg agtaaaaaaa caaggagtgt gtcgcgttac atcaatgagg
    43981 ctatgaccag tgaggagatg gacctatgaa gaagttgcta aataccttgt atttgacgca
    44041 agaagatttt tatgtcacta aagagggcga taacattgtt atcaagcaag aaggtaaggt
    44101 tctcaaacgg tttccgtttc ggattattga cggtattgtc tgtttttctt atttgggtgt
    44161 gtcgcctgct ttggtgaagt tatgtacgga gaatcagatt aaattatcgt ttcatacacc
    44221 acaagggcgt ttttgtggtc gctatattgg ttcaaccaat gggaatgtgt tgttgcgtag
    44281 agaacattat cgtttatctg atcgtgagga atctttggaa tacgcaaagc ggtttatttt
    44341 ggctaaaatt tccaactcaa ggaaatactt gctacgcttt aaacgagatc atcgtcaaca
    44401 gattgatacc aagctttttg aggctgttaa tgacgaattg atatgggctt tagagatggt
    44461 tcaggcagca gataataaag actctttaag agggattgaa ggccaagctg ctaatcagta
    44521 ttttcgcata tttaatgacc tggtgttgac ggacaaaaaa acgttttact tccaaggtcg
    44581 gagtaaacga ccacccttag attgtgttaa tgccctcttg tcttttggtt acagtttact
    44641 gacctttgaa tgtcaatctg ccttggaagc tgtcggatta gacagttacg ttggtttctt
    44701 tcacacggat cgtcctgggc gtgctagttt agcgcttgat ttagttgaag agttccgctc
    44761 atatattgta gatcgttttg tcttttcatt aattaataaa ggacaacttc agaaaaaaca
    44821 ctttgaggtt aaagaaaatg gtagtatttt attgacggaa aatggcagag ctatttttat
    44881 tgatttgtgg cagaagcgta agcatactga ggtagaacat ccttttacaa aagagaaagt
    44941 aaaacttatg ttattaccct atgtacaagc gcagctttta gctaaggcca tacgaggaga
    45001 tttagaaagc tatccacctt ttatggttta ggagatgtta tatgatggtt ttagtcactt
    45061 atgatgtaaa tacggaaaca cctgctggta gaaaaagatt gcgtcatgtt gccaaactct
    45121 gtgtggacta tgggcaacgt gttcaaaatt ctgtttttga atgttctgtg acacccgcag
    45181 aatttgtgga tataaagcac cgcttaacac aaatcattga tgagaaaact gatagtattc
    45241 gcttttattt attggggaaa aattggcaga ggcgtgtgga aacacttggt cgctcagaca
    45301 gctatgaccc agataaaggt gtcttattat tgtaaaaatc tcttgtgcga agctagcttt
    45361 cacagaaaaa ccttgcttgc tcgcgcaaaa ataacttaaa aaagaagcga aatggagata
    45421 aaaaggctta aaacacctct atgtgtgcca tccgtttctc tataaactgt gtcatttggc
    45481 gcagtctcac ccttcatggg tgagtggatt gaaattaaaa gtaggaggaa ctttagtttt
    45541 taaatggtcg tctcaccctt catgggtgag tggattgaaa tagccaattt gtcagcaaca
    45601 tcatcctttg atttgtctca cccttcatgg gtgagtggat tgaaatagtt atgggaccta
    45661 accagcaatc catgcttaaa gtctcaccct tcatgggtga gtggattgaa attgctaata
    45721 acggctctgc aagtggggca tgggcaagtc tcacccttca tgggtgagtg gattgaaata
    45781 tgattacacg caaaatgaac acaaggataa cgagtctcac ccttcatggg tgagtggatt
    45841 gaaattgcta cggcgtattt agtcacatac tcgcgtacag tctcaccctt catgggtgag
    45901 tggattgaaa gatgaacccg atctctcttt taatgaggtc gggtttttac atgcctttag
    45961 tcaaccattt atctgatagc gtatcaaatt caagtttttg catgttctag tctatggttt
    46021 gcgccactag ctttcggtaa actaagggta acttaagaga ggagttattt atgacactat
    46081 cacttgtatt aatggtatcg gtttttgggg caggcttgtt atcctttttc tctccgtgta
    46141 tctttccggt ccttcctgtc tatttaggca ttttactgga tgcagatgat tcaaagacga
    46201 ttactatatt tggtaaaaaa ctctattggt atggcattgt caaaacttta gcctttattt
    46261 ttggtctatc tactattttt gtgattttag gttacggggc tggtttttta ggaaatatcc
    46321 tttatgcggt atggtttcgg tacttactgg gagccttggt cattatcttg gggattcatc
    46381 agatgggcct cattaccatt aagagcttac aatttcaaaa atcactgact ttccataata
    46441 acaagaatcg caacggtttg ttcaatgcat ttatccttgg tttaaccttt agctttggtt
    46501 ggacgccttg tgtgggacct gttttgagtt ctgttctagc tttggtggct tcagggggaa
    46561 atggtgcctg gcaaggtggc gttttgatga ttatttatac tcttggattg ggcattcctt
    46621 tcctgcttat ctcttttgcg tcaggcattg ttttgaaaca gtttaacaag ctcaaacccc
    46681 acatgctttt actgaaaaaa gtaggaggcg ttctgattat agtcatggga atcttgctta
    46741 tgacaggaac cttaaataac ttagcacaac tttttggata aaggagaaac acaatgaaaa
    46801 aaggactatt agtaacaact ggtttggctt gtctcgggct actaactgct tgctcaaccc
    46861 aagacaatat ggctaaaaag gaaataactc aggacaagat gagcatggca gctaaaaaga
    46921 aagataagat gtcaacatca aaggacaagt ccatgatggc agataaatca tctgataaga
    46981 aaatgaccaa tgatggtcct atggcgcctg atttcgaact caaaggcatt gatggtaaga
    47041 cctatcgctt atcagagttc aaaggtaaaa aagtttattt gaaattttgg gcctcttggt
    47101 gttcaatctg tctatcaacc ttggcagata ccgaagacct ggctaaaatg tcagataaag
    47161 actatgtggt cctaacagtt gtctcgccag gtcatcaagg ggaaaaatca gaagcagact
    47221 ttaaaaaatg gttccaagga acagactata aggacttacc agtcttgtta gatccggatg
    47281 gcaagttatt ggaagcttac ggcgtcagat cttacccaac agaagttttc attggaagtg
    47341 atggtgttct tgctaaaaaa tacattggtt atgccaaaaa atcagacatc aaaaagaccc
    47401 ttaaaggtat acattaggaa ggaccagctg ataggtatta gaaaaaagga gttgagttta
    47461 tggaacacaa atggaaatta tggctattta tcgttggaat ggtcttgtta ataggcggag
    47521 cttctgttct cattcagaaa ggtcaagcca aggcttttag tcaaggcaag cctcaactac
    47581 cagctaaaaa agtcaaatcc actaaagcag atcccaatgc ccctgttgat caaaaaatga
    47641 tttacctagc tggtggctgt ttctggggcg ttgaagaata tttttcacaa gtggatggcg
    47701 tcttagatgc ggtgtcagga tatgccaatg gtagaggcga taccactaat taccagttaa
    47761 ttcatcagac tggtcatgca gaaaccgttg aagtggccta tgatgcgaac cgtattagct
    47821 tgaaagaatt attactgcat tttttccgaa ttattgaccc aaccagtctt aataagcaag
    47881 gaaatgatcg cggtagtcaa taccgaactg ggatttacta tactgacaaa gcagatttag
    47941 ctattattga tgaggtcttc aaagaaaaag ctaaggatta caagaaaaaa atagtggttg
    48001 aaaaggcgcc attgaaacac tttattaagg ccgaagagta ccaccaagat tacctcaaga
    48061 aaaatccaaa tggctactgc catattgaca tcaaccaagc gacctatcct gtgattgatg
    48121 aaagcaagta ccccaaacca agtgccactg agatcaaagc aaaactatct gcagacgaat
    48181 accgagtgac gcaaaaaaac gaaactgaaa aagctttttc taatcgctac tgggattctt
    48241 ttgatgcagg aatttacgta gacgttgtga caggagaacc gcttttctct tcaaaagaca
    48301 aatttgaatc aggttgtggt tggccaagct ttagccgccc catcagccca gacgttgtcc
    48361 gctacaagga agataagagt ttcaatatga cgagaacaga agtgcgcagc cgttcaggga
    48421 attctcatct ggggcatgtc tttactgacg gacctaaaga ccaaggcggc cttcgttact
    48481 gcatcaatag cttgtctatt acctttattc caaaagctga tatggaagct aagggctatg
    48541 gttatttatt atcatctgta gaatagggtt aggcctaaaa atctgatata atagaagaaa
    48601 gactagtatg agagggccat gcaaggccct ttataaagat aaggagacac cgtgtgtact
    48661 cattgttaat tgtagaagac gaatacctta tccgccaagg tattcgttct ttggttgatt
    48721 ttagccagtt caagattgat cgggtcaacg aagcagaaaa tggccagttg gcttgggact
    48781 tgtttcagaa agagccttat gatattattt tgacggatat caatatgccc aaattaaatg
    48841 ggattcaact agcagaactc attaaacagg aatcccccca aactcatctg gtatttttga
    48901 cgggctacga tgattttaac tatgccttat ctgctttgaa attaggggca gatgattact
    48961 tgctcaaacc cttttccaag gcagatgtag aagacatgtt aggaaagctc cagcaaaaat
    49021 tagaactttc caagaaaaca gaaaccattc aggaattggt tgagcagcct caaaaagaag
    49081 tatcagcaat agcaatggct attcatgagc ggttggcaga ttctgatttg accctaaaaa
    49141 gcttggctca gcagcttggt tttagcccta attaccttag cgtcttgatt aaaaaagagt
    49201 tagggatgcc ctttcaagat tatctggtac aagaacggtt gaaaaaagcc aagcttctct
    49261 tgttaaccag taaccttaaa atctatgaaa ttgcagaaca ggtcggtttt gaggacatga
    49321 attatttttc tcagcgcttt aagcaactgg taggcgttac cccaagtcag tataaaaaag
    49381 gaggccaggc atgaagcgtt atcccctact ggtccagttg atttcttatg tctttgtgat
    49441 cgtaattgcc ctcattacca cgcttggttt gctttattac cagacgagtt ctcgtaatat
    49501 caggcaatta attgaacgtg atacccggca gagcattcgg caaagttccc aatttattga
    49561 cgcttacatc aagcctctta aagaaacaac ttcggtgctg gcgaaaaatt cggaaattca
    49621 agactttgct agtcaaattc atcaagaaaa tgacaaacag gttcttcagc tcatgaagat
    49681 ggttcttgcg accaattccg atttacaagc agctgttctg gtgactaagg atggccgaac
    49741 cgtttctacc aatcctcagt tgattatgaa aacctccagt gatatgatgg cagaaccctg
    49801 gtataaagca gccatagacc gtcaagccat gccaatctta accccagctc ggcaattatc
    49861 cctttcttct aaaaaagaat gggtagtttc tgtgacccaa gaggtagtgg atgctgctgg
    49921 tcataattta ggcgtgataa gacttgatat tgcatatccg actattaaag cgtctttaga
    49981 tcagcttcag ctaggccgcc aaggctttgc ctttattgtg aatgataagc atgaatttgt
    50041 ttaccatccc aaaaagagtg tttacagttc ttctaaggag atggctgcga tgaagcctta
    50101 tttagcgatt cagaatggtt acactaagga caagacatct tttgtttacc aaaaactcat
    50161 tcctaacagt caatggactt tagtgggagt ggcgtcactg gatcagttgc accgggtgca
    50221 gcgccaaatt ttttggtcct ttcttggaac agggcttcta gcctgtctga tttgtggctt
    50281 tgcaactgtc ttagtcttac gcagatggat tcgtcccatt caacaattgc agcaagttat
    50341 tcttgctatt caaaaaggag atcgtcagtt acgtgcccaa gaaacgggtt ctccagaatt
    50401 gacagacctt gcccaacagt ttaatgcgct cttagatcaa attgatagct tgatggttgc
    50461 cgttgcggat aaggaaaagg cgattgggca gtacaggtta caagccttgg ctagtcagat
    50521 taacccgcat tttctctata acaccttgga cactattatt tggatggcag aatttaatga
    50581 cagcaagcgc gtggtagaag tgaccaagtc tctagctaag tattttcgtt tggcccttaa
    50641 tcaggggaac gaatacattc gtttggcaga tgaactggat cacgttagcc aatacctttt
    50701 tattcaaaaa cagcgctatg gagacaagct aagttatgaa gtgcaaggct tagatgtcta
    50761 cgcagacttt gttattccta agcttatctt acagccctta gtagaaaatg ctatctacca
    50821 tggcatcaaa gaagtcgatc gcaaaggcat gatcaaggtt acggtatctg atacagctca
    50881 gcatctggtg ttgactgttt gggataatgg taaaggcatt gaagactctt cactgaccaa
    50941 tagtcagagc ttgttgacta ggggaggtgt gggccttaaa aatgttgacc agcggttaaa
    51001 acttcactat ggtgaaggct accacatgac cattcatagc cagtcagacc agttcactga
    51061 aatacaatta agccttccta aaatgcatga attaatggca gacgacacac aggaaaacga
    51121 gtaaggttac aggaagtgca tgtcagccat ttccctaagt tagggtattg gagataggaa
    51181 ccttagaaag gatatcatga gtttagcaac tgactatttt agccgacaga cccccatagt
    51241 tgaaaagcta gtggcttacg gttttgaaaa acgagataat ggttatttct ataacgaacg
    51301 gtttatggaa ggagaatttg aggcgcagct taggattgat gaggctggca atatctggga
    51361 tcgggttatt gattgtgatt tggaggagga ttatttgcct ttacaacaag cagcctggca
    51421 aggaacctat actgggcagg ttagagcagc ctatttggaa cttttggagc gcttatcagt
    51481 agcctgtttt gaagtcactc cttttcagtc aatgcaagct aatagacttg ctaagcatat
    51541 caccaaagaa tggtctgacc caatggacta tccttttgag aagcacccag accttgcaac
    51601 ctaccgggta gggggcaaat ggtatgctat gattttttct ctcttggctg ataaattaga
    51661 ccagatacca gagagattag taggacagac atgtgaagtg atgactgtca aagttaatcc
    51721 caaggattta cctcagttac tgcagcaaga gggcatttac cctgcctacc atatgtcaaa
    51781 aaacaattgg gttagtgttg tcttggatga taaagtaaca gatgatcagc tttgggggtt
    51841 agctacgcaa agtcgtcaac tagtcaaccc caacggtctt tctaatccta atagtcctga
    51901 ttattgggtc attccagcta atttgaaata ctatgatatt gatgcagaat ttgcagccaa
    51961 tgatgtgatt ttatggaccc aaaaagctgg tattgccgtg ggagactacg tgctgattta
    52021 tataacagcc ccagtcaaat ccattcgcta tgcctgccaa gttctagaaa ctgatatacc
    52081 taacgagggt tatcgtaaaa atcttaacat tgacaaactc atgcgtctcc gaaaatgcca
    52141 acagtacaag gatggtctct tgtcttttga ccttatgaaa gaacatggcg tagctgcagt
    52201 gagagggcca aggcgattaa gccctcaatt aattgcattt ttaaaggaaa aagagtattt
    52261 taaagagaac aactaaagga gaataagaga tggttgaatt tgtagcagat caaagttttt
    52321 gggaactttt tccagatgcc aaactaggtg tcgtcttatt aaaggatgtt cagaatcaag
    52381 cagagtcacc agaagatgtc aaacagctct tagcagatag ccatgagtta gcaaaagctt
    52441 atttaacagc agacaatttt agtgataatc aggtggttca agtctaccgc aaggcctatc
    52501 aacactttaa aaccaaaaaa ggagctcgct ctagcattga agcccttctc aagcgggtgt
    52561 caaatggtca aagcattccg tcgatcaatc cgctagtgga tatttataat gcggctagtc
    52621 tacgttttgg tttacctgtt ggagccgaag atagtgacag ttttatcgga gatttgcgtc
    52681 tgacgataac agatggtggt gacgactttt acttgattgg ggatgctgat aacaacccaa
    52741 ccttgccaaa tgagctgtgt tataaagatg atattggagc ggtttgtcgt tgccttaact
    52801 ggcgagatgg cgaacgcacc atggtgacag aacacaccaa aaatgcattt ctgattatcg
    52861 aagctcttga tcaagaaggt caaaatagat tgcaagaagc tcttgacttc attgaaggca
    52921 gcgcaaaaat gtaccttcat gcaaccccct ctttgcatgt gttggataaa gacaatccac
    52981 acgtgccact ttttacagaa aactagatta gtaggatgag ctgtgtaaaa tagaaggtta
    53041 acaaaaaaag cgagtaaacg aatgtcctgt catttaggtt ttcgtttact cgctttttga
    53101 tgagatttta ctgctgtcct agcaaaaggt gaggatgagg tcgtatatca catagaggtt
    53161 ttctgttaag ccttatttgt tactaaagaa gaaaggtggc gtgtaatgac taagggtttc
    53221 gtaacaagcc ttggcttgct cattgtcttc acagacaatc aagcaagtat catcaccaca
    53281 gaccgttgct acaatttctg gaatttgcat ggcatctaaa atggagccaa aggattgggc
    53341 tagtccaggt aacgttttta aaataatttg atgttgaact atctttaaca tgaccaaagc
    53401 gtcttccatg taaaaacgaa gacgatgttc ccagcgggtt tgtgaaatgg ctaacgcttc
    53461 atagtgtgtg tcgtttccag aagttacttt gaccaggttc aattccttca tgtcacgtga
    53521 tagggtagcc tgagtgatcg tgatgccatt tttttgcaac cgttcttgta attcttgctg
    53581 tgtatgtata gttgtctcag agatgaggga acgtatgagt tggtgacgcg tctctttctt
    53641 attcattgtt ataatcttcc tttaacgtaa ttgataacaa tccgagtata gcaaaaagag
    53701 gagaaggtgt aaagtttttg atgaaccgct tacaaaatag cttttttatg gtaaaataaa
    53761 gatgatgttt agaaaaagga gatttgtgtg attcgaagag aagattatca ataccttaga
    53821 aaactaaacg attttcgcta cttttctatt gaacaatttg acaaaattgt agggcagatg
    53881 gaattccgaa aagctaaaaa ggaccatatc cttttttttg agggagataa aagagataag
    53941 ctttttctag tgacctctgg ttatttcaag gtggagcagt ccgatcaatc aggaaccttc
    54001 atgtatacgg atttcatcag acacggcacc atttttcctt acggtggcct ctttacagat
    54061 gattattacc atttttcagt ggtagccatg acagacgtga cttattttta ctttccagtc
    54121 gatttatttg aagattattc gcttgaaaat cgtctacaaa tgaaacactt atatagtaag
    54181 atgtctaagc tgctcgagtt acatgagttg agggtccgaa acttgattac atcaagtgct
    54241 agttctcgtg tgattcaatc tctggcgatt ttgctggttg aaatgggtaa agacagtgat
    54301 accttacctt ttcaattaac aacaacagat attgctcaaa taagtgggac aacaagagaa
    54361 acagttagcc atgtgcttag ggatttgaag aagcaagaat tgattaccat aaaaggtaag
    54421 tatttgactt atctagataa agactatttt ttacaataca caaagtgaat taaaggtcag
    54481 aacactttat tttaaaagtt tttctgactt attttaattt ataagtataa atttttacac
    54541 taagatgtaa aaaacataca agtaaacgaa tacaaatcta taaaaataaa aacaacgctc
    54601 aaaaaatgta agcgattact caaaatggct gtgagaaaaa ccctattttt atctttttta
    54661 aggagtacac taggaatata agcaagagtt aagaatcttg acggtgaatt cacaaaaacc
    54721 aattagaaag aggtaattct tatgactgct caaacaccaa ttcatgttta ttctgaaatt
    54781 ggaaaattaa aaaaagtgtt gctccacaga cccggtaaag aaattgaaaa tcttatgcca
    54841 gactacttgg aacgcttgtt gtttgatgac attccattct tagaggatgc ccaaaaagaa
    54901 catgatgctt ttgcccaagc tttgcgtgac gaaggtattg aagtcttgta ccttgagacc
    54961 ttagctgcag aatctcttgt cactccagaa attcgcgaag ctttcatcga tgaataccta
    55021 agtgaagcta atatccgtgg aagagctact aaaaaagcca ttcgtgagct gttgatggct
    55081 atcgaagaca atcaagaatt gattgaaaaa accatggcag gggttcaaaa atctgaactt
    55141 ccagagatcc cagcatctga aaaaggcttg actgacttgg ttgaatccaa ttacccattt
    55201 gcgatcgacc caatgccaaa cctttatttc acacgggacc cattcgcaac tatcggtaca
    55261 ggtgtttctc ttaaccacat gttctcagaa acccgtaacc gtgaaaccct ttatggtaaa
    55321 tacattttca ctcatcaccc aatttacggt ggtggcaaag tgcctatggt ttatgaccgt
    55381 aatgaaacca ctcgcattga aggtggggac gaacttgttc tttcaaaaga tgtgcttgcg
    55441 gttggtattt ctcaacgtac agatgctgct tctattgaaa aattgttggt taacatcttt
    55501 aaacaaaacc ttggcttcaa gaaagtattg gcctttgaat ttgcaaataa ccgtaaattt
    55561 atgcacttag acactgtctt taccatggtt gactatgaca aatttaccat tcacccagaa
    55621 attgaaggcg accttcgtgt ttactctgtc acttacgaca atgaagaact tcatatcgtt
    55681 gaagaaaaag gtgatttagc agaacttctt gctgctaacc ttggtgttga aaaagttgac
    55741 cttatccgtt gtggtggtga caacttagta gcagcaggtc gtgaacaatg gaacgatggt
    55801 tctaacaccc ttactatcgc accaggtgtg gttgtggttt ataaccgtaa caccattacc
    55861 aatgctattc ttgaatctaa aggcttgaaa ttgatcaaga ttcacggaag tgaattggtt
    55921 cgcggtcgtg gtggacctcg ttgtatgtca atgccatttg aacgtgaaga tatttaataa
    55981 gctatggtaa aggtggttat aggtcagaag cctttttaaa gggcagctag tgtttatctt
    56041 cgattctgtg tctttgtcct tcaatgaaat tttgtcatga cagataaatt tgatgccaat
    56101 gacgaaacaa gaacggttta tgcagtcgtt tatgacaatg accagcccgt ttcaacagga
    56161 caatttttag ctgaaacgaa aatagaagca cgattgacac gcattgtaac cttagcagat
    56221 tattgtggtt gcggttatgg tgccaaagtc actgaagcgc tagaaactta taccagacga
    56281 gaaggctttt accaactaac cattcacagt gaactgacag cacaaacctt ttatgaaaac
    56341 ctaggttatc agacctatgg ttccaagtat ttagaagatg gtgagtattg tcaatccctt
    56401 gttaaaacca ttcttaaatg ggagaagaat atggacatag caatgctaat tgcgattgtt
    56461 ggtggtctat taggctgcta tctctatctc acaaaaaata atgaacccaa agattaagtt
    56521 aatactcgaa ggagacaata gatgacacaa gtatttcaag gacgtagctt cctagcagaa
    56581 aaagatttta cacgcgctga attagaatac cttattgatt tttcagctca tttgaaagat
    56641 ttgaaaaaac gtggtgtgcc tcatcactac ttagaaggta aaaacattgc cctcttgttt
    56701 gaaaaaacat caactcgtac gcgtgcagct tttacaacag cagccattga cctaggtgct
    56761 cacccagaat accttggtgc caatgacatc caacttggta aaaaagaatc aactgaagac
    56821 actgccaaag tattgggtcg tatgtttgat gggattgaat tccgtggctt tagccaacgc
    56881 atggttgaag aattggcaga attctcaggt gtgccagttt ggaatggttt gactgatgaa
    56941 tggcacccaa cccaaatgct tgctgactat ttaacagtga aagaaaactt tggcaaactt
    57001 gaaggcctta cccttgttta ctgtggtgac gggcgtaata acgttgccaa ttcccttctt
    57061 gtgactggtg ctatccttgg tgttaatgtt catatcttct caccaaaaga acttttccca
    57121 gaagaagaga ttgtgacatt ggctgaaggc tatgctaaag aaagtggcgc tcgtatcctt
    57181 atcacagaag atgctgacga agctgttaaa ggcgcagacg tgctttacac agatgtttgg
    57241 gtatcaatgg gtgaagaaga caaattcaaa gaacgtgttg aattgcttca accatatcaa
    57301 gtcaacatgg accttgttca aaaagcagga aatgacaagc ttatcttctt gcactgcttg
    57361 ccagctttcc atgacacaaa taccgtttat ggtaaagacg ttgctgaaaa attcggcgtg
    57421 aaagaaatgg aagtcactga tgaagtcttc cgcagcaaat acgctcgtca ttttgaccaa
    57481 gctgaaaacc gcatgcacac tatcaaagcg gttatggcag caacccttgg taacctcttt
    57541 attccaaaag tgtaataagg actggtactc cttaactcat ttcacatatc aatgtgaccc
    57601 ctttaattta acaatttaac tacttaaaaa cgtactttaa ctacatgaca agtcgttctg
    57661 gttttcgcgt ccttgaccgg aactagaacg gcttattttt atgaaaaggt aagaggtaat
    57721 cattatgaca gaagaaaaaa aacggggttt tagaattcct tcttcttaca ccgttctttt
    57781 tatcattata gccatcatgg cagtgttaac ttggtttatt ccagctggcg cctacgaaac
    57841 cgctaagggc ggtggtgtta tttcaggaac ctacaaaaca gtagcatcca atcctcaagg
    57901 attttttgac atcttgatgg ctcccgttcg aggcatgtta ggtgttgaag gcactgatgg
    57961 tgctattcaa gtgtctttct ttatcttaat ggttgggggc tttttaggag ttgtcaacaa
    58021 aacaggtgct cttgacacag ggattgcgtc agtggttcgt aaaaacaaag gtagagaaaa
    58081 aatgctgatt gctattttaa tccctttgtt tgctctaggt ggaacgacct atggtatggg
    58141 ggaagaaacc atggcctttt acccactttt aattcctgtt atgattgcgg ttggttttga
    58201 cagtattgtt gctgtagcca ttattttgat tggttctcaa attgggtgtc tagcctccac
    58261 tattaaccca tttgcaactg gtgtagcagc tgatgctgct ggtgtcagca ttgcagatgg
    58321 aatgatttgg cgtgttatcc aatgggttat tcttgtcggc atgtctattt ggtttgttta
    58381 caattacgct agtaagattg aagaagaccc aagtaaatca ttggttgcag acaaggaaga
    58441 agagcataag gaactcttcc agttgcaaaa ttctggagaa gacttaaaca agcgccaacg
    58501 aaacgttttg accattttta ctttgacctt tgtcattatg attcttagtt tgattccgtg
    58561 ggaagatttt ggcatcaaat tctttactaa tatcaatact tggttaacca caatgcctat
    58621 cttaggggga gttattggga aaaccatggg agcatttggt acttggtatt tcccagaaat
    58681 caccatgctc tttatcatga tgggtgtctt agttgctatt gtgtatcgta tgagtgaaga
    58741 agactttttt agctcttttt tgactggtgc aggtgaattt ttaggtgttg ccatgatctg
    58801 tgctattgca cgcggtattc aagttatcat gaatggtggt atgattacag ccactatctt
    58861 acacttaggt gaaacaagtc tttctggttt atcttctcaa gtttttgtga tattagctta
    58921 tattttctac ctcccaatgt ccttcttgat tccatcaaca tcaggacttg ctggggctac
    58981 aatgggaatt atggcaccgc ttggacaatt ctcaaatgtc cctgctcacc ttgttattac
    59041 agccttccag tcagcttctg gaatcttaaa catgatttct ccaacttcag caatcgttat
    59101 gggagcactt gcgcttggtc gcgttgacct tggtacttgg tggaaattca ttggtaaatt
    59161 tattgtaatg gtgatgcttg taagcgtgct attacttgta gttgcaacat tcttttaaca
    59221 gataggaggt tcctatggaa tcctatatca cacctaaaca tcaagaggcc tgtgtagctg
    59281 ccattaaaca gatcgtttct tacccttctg tttgtcatga aggagaaaat ggcacacctt
    59341 ttggacaggc cattcaagat gttctcgaag caaccttaga cttatgtcaa ggtcttggtt
    59401 ttcatactta tattgatcct gaaggttact atggctatgc tgagttaggt gaccaaaaag
    59461 aggtcttggc tattctttgc catttggacg ttgttccaga aggagatcgt cagttatgga
    59521 agacagatcc ttttgactgt gttgaggcag acggctgttt atttggtcga ggcactcaag
    59581 acgataaagg gcctactatg atggcgctat ttgccaccaa agccttgata gatgcaggcg
    59641 ttacctttaa taaacgcatt cgttttattt tcggaacaga tgaagaaact ttgtggcggt
    59701 gtatgaatcg ctacaatgat gtagaagaac aggctacctt tgggtttgct cctgattcaa
    59761 gtttcccttt aacctatgcc gaaaaaggcc tacttcaggc aaaattagtg gggaaaggtt
    59821 gtgataaact gtcacttgaa atcggacaag cctacaatgt tgttcctgca agagcttctt
    59881 ataaaggcaa taagcttgag gctttacaaa aagaactaga taagcttggc tttgagtacg
    59941 tcgtcaaaga gggagaatta acggtttatg gtctcgccca acatgctaaa gatgctcccg
    60001 atggcatcaa cgctatgatt aggcttgcca aggctttagt ggtccttgaa cctaacaaaa
    60061 cccttgattt tcttgctaat gtcattgatg aagatggcag agcacttaat atttttggca
    60121 gaatcgaaga tgaaccttca ggcaaattaa gctttaatgc cgcagggctt accttaacca
    60181 aagacaaggc agaaattcgc ctagatattc ggattccagt tttggcagat aaggaaaaat
    60241 tagtccaaca attaagccaa aaagcacaag aatacggcct aacctatgaa gaatttgatt
    60301 atttggcccc attatatgtg ccattagaca gtgaattggt aacaaccttg ttatctgtct
    60361 atcggaaaaa aacaggtgat caaagccctg cccaatcatc aggaggggca acctttgcta
    60421 gaacaatgaa gaattgtgtt gcctttggtg cccttttccc tgatgctgtt caaacggaac
    60481 accaagaaaa tgaacatatt gttttagcgg atgcttaccg cgctatggat atttatgcgg
    60541 aagctattta ccgactaacg cgataacaag atatgaggag taattatgac gaaacaaaaa
    60601 atcgtagtcg cacttggagg aaatgctatt ctttcaacag atgcgtcagc aaaagcacaa
    60661 caagaagcct tgatgtccac atcaaaatca ttggttaaat taattaaaga aggtcatgaa
    60721 gtcatcgtga cccacggcaa tggcccacaa gttggtaatc tcttattaca acaagcagca
    60781 gcagattctg aaaagaatcc ggctatgcct ttggatactt gtgttgccat gacagaaggt
    60841 agcatcggtt tttggttagt taatgccctt gataatgaat tgcaagccca aggtattcaa
    60901 aaagaagtgg cagctgttgt cactcaagtg atcgtggatg ccaaagaccc agcttttgaa
    60961 aacccaacaa aaccaattgg tccatttctt accgaagaag atgccaaaaa acaaatggcg
    61021 gagtctggtg caagtttcaa agaagatgca ggtcgtggct ggcgtaaggt tgtgccatca
    61081 ccaaaaccag ttggtattaa agaagccaac gtcatcagaa gtctggttga ttctggcgtt
    61141 gttgtggtta gtgctggtgg tggcggtgtg cccgttgtgg aagatgcaac tagcaagacc
    61201 cttacgggtg tggaagccgt tattgacaag gactttgcta gccaaaccct ttcagaattg
    61261 gtggatgcag acctctttat cgttttgaca ggggttgaca atgtttatgt taacttcaac
    61321 aaacctgatc aaacaaaatt ggaagaagta acggtctctc aaatgaaaga gtacatcaca
    61381 caagaccaat ttgcaccagg tagtatgtta ccaaaagtgg aagctgccat tgcttttgtt
    61441 gaaaacaaac caaatgctaa agccattatc acatcgctcg aaaatattga caatgtacta
    61501 tcagcaaacg ctggaacaca aattatcgca gggtaatcaa gaggattttt agttctgttt
    61561 aaaagactca tttaatggta ttttctgaag agtacgactg acataaagag tttatactgt
    61621 ttttaaagga aaagagtgtg ccataataaa aaacaataat agtattagaa aaggctaatt
    61681 ttattgagaa ttagcctttt cttttggctt tgataggtgt ataataacca tactattttt
    61741 tatttttcaa aatattagaa taaacaaaag tagacaacgt ataaagagaa ctgctaagtc
    61801 gttgagttca ttagtcccaa aaagattacc aaaaaagaag gaagaactat gaagaaaagt
    61861 tttattcatc aacaagagga gatttccttt gttaaaaata cgttcactca gtatttaatt
    61921 gctaagttag atgttgttga agtgcaagga cccattttaa gtcgggtcgg ggatggtatg
    61981 caagataatt tgtccggtac tgaaaatcca gtatctgtca atgtcttgaa aattcctaat
    62041 gcaacctttg aagttgtgca ttcattagca aaatggaaac gtcacacctt agcccgtttt
    62101 gggtttaatg aaggtgaagg ccttgttgtt aatatgaagg ctctccgacc tgatgaggat
    62161 tcacttgacc aaacccattc tgtctatgtt gaccaatggg actgggaaaa agtcatccct
    62221 gatggcaaac gtaatctcgc ttacctcaaa gaaaccgttg aaaccattta caaggtcatt
    62281 cggctaactg aattagctgt agaagctcgt tatgatattg aggctgtttt acctaagaaa
    62341 ataaccttca ttcataccga agaattggta gcgaaatacc ctgatttgac gcccaaagaa
    62401 cgtgaaaatg ccattactaa agaatttgga gcagtctttt taattggtat tggcggggtt
    62461 ttacctgacg gtaaaccaca cgatggccgc gctcctgact atgatgactg gacaacagaa
    62521 actgaaaatg gctatcatgg gcttaatggt gatattttgg tttggaatga ccaacttggt
    62581 tcagcctttg aattatcctc aatggggatc cgtgtggatg aagaggccct aaaacgtcag
    62641 gtggaaatga ctggtgacca agaccgctta gcctttgatt ggcacaaatc tttgttgaat
    62701 ggacttttcc ctctaacgat tggtggagga atcggtcaat cacgtatggt catgtttttg
    62761 ttgcgtaaaa aacatattgg agaagttcag acctctgttt ggccccaaga agttcgtgat
    62821 agctacgata atattttata agtaatcaca tcattttgct aagttttcca cttgtataag
    62881 agactttaaa taaatgatca gaaatattga aaaaagaaat catttttaag gtttagagct
    62941 agaaatttgc tataataaat gttatgagag ttgtatcagg tgaatttggt gggcgtcctt
    63001 taaagacgct cgatggaaag ataacacgcc ctacttcaga caaagttaga ggtgcgattt
    63061 ttaatatgat aggaccttac tttaatggtg gtcgtgtttt agatttgttt gcaggttcag
    63121 gtggattagc cattgaggct gtttctcgtg ggatgtctgc tgcagttttg gttgagaaga
    63181 atcgtaaagc gcaagctatt attcaagaca atattataat gactaaagct gagaatcggt
    63241 ttaccttgtt aaaaatggaa gctgagcgag ctattgattg cttgactggt cgatttgact
    63301 tagtcttttt agaccctcct tatgccaaag aaacaattgt ggcaactatt gaagctttag
    63361 cagctaaaaa cttattgagt gaacaggtta tggttgtctg tgagacagat aaaacagtct
    63421 tgttgccaaa agagattgca acgttaggta tttggaaaga aaaaatttat ggaattagta
    63481 aggtaacagt ttatgttaac taaaatagga ctttatacag ggtcatttga tcctgttaca
    63541 aacggtcatc tcgatattgt taaacgggca agtggcctat ttgatcaaat atatgttggg
    63601 atttttgata atcctaccaa aaaaagctat tttaaactag aagttcgtaa agcaatgctt
    63661 actcaagctc tggctgattt tacaaatgta attgtagtaa cttcgcacga acgtttagct
    63721 attgatgtag ctaaagaatt acgagtaact cacttgatta gaggtttgcg aaatgcaact
    63781 gactttgagt atgaagaaaa tttggaatat tttaatcacc ttttagctcc aaatattgag
    63841 accgtctatt tgatatcaag aaataaatgg caggccctta gctctagtcg tgtgagagag
    63901 ctaattcatt ttcagtcttc cttagaaggt ttggttcctc agtcggttat tgctcaagtg
    63961 gagaaaatga atgaaaagac ttaaaaaaat caaatggtgg ttagtgggtc tgctagcttt
    64021 aatctctttg ttgctagcgt tattttttcc gctaccttat tatattgaaa tgcctggagg
    64081 cgcttacgat attcggactg tcttacaagt caatggcaaa gaagacaaac gaaaaggggc
    64141 ttaccagttt gttgcagtgg gcattagtcg tgccagcctc gctcagctat tatatgcttg
    64201 gctgacaccg tttactgaaa ttagtacagc agaagataca acaggcggat acagcgatgc
    64261 tgatttcctt cgaattaatc aattttacat ggaaacatca caaaatgcag ctatttatca
    64321 agctttatcc ttagctggaa aaccagttac attagattat aaaggcgtat atgttttaga
    64381 cgtaaacaac gaatctactt ttaaaggaac gttacactta gcagatactg taacaggtgt
    64441 aaatggtaaa cagtttacta gttcagcaga acttattgac tatgtttctc acctaaaact
    64501 aggggatgaa gttacggttc agtttacgag tgataataag cctaaaaaag gagttggccg
    64561 tattatcaaa ctgaaaaatg ggaaaaatgg gattggcatt gccttgactg atcatacaag
    64621 tgtcaattca gaagacacag tgatctttag tactaaagga gtaggaggac ctagtgctgg
    64681 tctaatgttt actcttgata tatatgatca aataactaaa gaagatttac gcaagggccg
    64741 tacaattgca ggtacaggaa ctattggcaa ggatggcgaa gtaggagata ttggtggtgc
    64801 aggtcttaaa gtagttgcag cagctgaagc tggtgcagat atattttttg ttccgaataa
    64861 tcctgttgat aaggaaatta aaaaagttaa tccaaatgct ataagtaatt acgaagaagc
    64921 caaacgggca gccaaacgac taaagaccaa aatgaagatt gttcctatta cgactgttca
    64981 agaggcactg gtttatcttc gcaaataaaa taactatgaa tgtattatat tcaattatat
    65041 tcacgctatt aactcataaa aaacggttga accagataga cagatccttg accagtcttt
    65101 tgggttcaat cattttttac ataaaacata tctaacttga cagcgtaaaa aagatgttat
    65161 aaaagtctag tggtaaaaag gcaatagaga attgagtaaa ctttagtcga ttatctggaa
    65221 atagagcata ctaaaaacac ctagtgaaaa ttgatttttt tcactagctc atccaagaac
    65281 ttgcgcagat aatcatgagt ccattccatg actctattat tctggaaagc cttgcaatag
    65341 acaagttaac gttataacaa ctaaattaaa aacttgagat tgaaaaatcc ccataaactt
    65401 attttacaag gaggtaaggc tatggtaacc attaaacaag ttgctgaaga agcaggtgtt
    65461 tctagatcaa cagtctccag gtatatttct caaaaaggat atgtatctga tgatgcaagg
    65521 cataaaatca aagcagcgat agcaaaatta cattacactc caaatgtctt ggcgcagtca
    65581 ttgaagacga aaaaaaatca actagtcggt ttattattac cagacatttc caatcctttt
    65641 tttccgaggt tagcaagggg agcagaagaa tatttaaaag aaaaggggta tcgggttatg
    65701 ctaggaaata tttcagacag cgaagctctt gaagaagaat acgtccatgt ccttcttcaa
    65761 agcaatgctg ctggcattat tactacccat gactttacaa agcggtatcc tactcttgct
    65821 attccagttg tagtggtaga tcgtgttgac caagagaccc agtacggtgt cttttcagat
    65881 aatagggcag ggggcttatt ggcggctcag actgtctggc aagcaggggc aaaagaagtt
    65941 ttgttaataa gaggtccgct ggataatgct gaaaacatta atgagcggtt tgaagctagt
    66001 ttttcttacc ttcaaaaaca agacgtgact atgtatgtgt gtgatagtca gaattttgat
    66061 tttgaaagta ttcagctaga agctagttac aacctcaagt gttacccaac aatagacagt
    66121 attatagcac cttctgatat ccatgctatt gcttatattc atgaactgca ttctcaaggt
    66181 aaaaagattc ctcaagatgt tcaaataata ggttatgatg acattttaat gagtcaattt
    66241 atttatcctt ctttatcgac tattcatcaa tcctcttatt tgatgggccg ttatgccgcc
    66301 gaattagttt atactattgc tagtcaatta actgtgaaag caaatcggat taaattgcct
    66361 gttcactacg ttgagcgaga aacaataagg aaaagataag taataatatt cgtccagatt
    66421 ttagcaggta tgatgaagat ttgttgggat ttaccttcta ctttaaaaga tgttatctgt
    66481 cattactttc atcgctatca gtcaaaacgc attcttatgc aactcttaac cttaagctta
    66541 aggtcttttt gataacatag aggaatgtta cacgatgatg acgcaataaa gcctaaatat
    66601 agtaattgtc gtgattttat agctagtgag taatgagata gcaagtctct catttactta
    66661 caaaagtcaa aaaatagtgt ataatggttg agttacagat aacactgcaa aaaagataac
    66721 aagtgtccat aattatctaa gactataaag gcgatataga cagatataaa aaagatgacg
    66781 aatcagttat cactggacaa ttaaccgatt tagttacaac taatggattt ttcagaaagg
    66841 tgtcaaatga aaaaagaaat ttcgccagaa atgtacaact ataataaatt tccaggtccc
    66901 aaatttattc attttgaaga gcaagttaag gctgaaggca ttgatttgtt actcttagaa
    66961 gatgttaaga acgcttttga tacgactagc tttggtcaac gttatacaga agttctccta
    67021 aagtatgact atattgttgg cgattgggga aatgaacagc ttcgtcttaa agggttttat
    67081 aaggatagtg acgatatcaa gaaaacgaat cgcatctcac gtttagaaga ttatattaaa
    67141 gaattttgca attttggttg tgcttatttt gttttagaaa atcttcatcc acaagatatt
    67201 aaatttgaag aggagcgcca accaagacga aagaaatcac ctaaatcaaa atcaaatcgt
    67261 cgcaagccaa actattcaaa tcagcagccc gcaataccta agagtaaatc gaagcgggta
    67321 tcaaaagaaa agcaacctga aaaccaagcg tttaccagtc aaaaacgtcg aagtaatact
    67381 aagcataaag aaaagtcaaa acgtaatcag actagtcaac ttaataccaa aattagtcat
    67441 tttatcatca gaaagaaaga taaataatcc atgaaaccat cgatttatag cttaacacgc
    67501 gatgaactga tcgcgtgggc agttgaacgc ggccaaaaac agtttagagc tactcaaatt
    67561 tgggattggc tctataaaaa aagagttcaa tcttttgagg agatgacgaa tatttctaaa
    67621 gattttgttt ctattttaaa tgatagtttc tgtgtcaatc ctttaaaaca gcgagttgta
    67681 caagaatcag ctgatggtac agtaaaatat ttatttgaac tgcccgatgg tatgttaatt
    67741 gaaacagttt taatgcgtca acattatggt cattctgttt gtgtgacgac tcaagttggc
    67801 tgtaacattg gctgtacttt ttgtgctagt ggattgatca aaaagcaacg tgatctaaac
    67861 agtggggaaa ttacagctca aatcatgtta gtccaaaaat attttgacga tagaaagcaa
    67921 ggtgagcggg ttagccatgt tgtcgtaatg ggcattggtg aaccttttga taattacaaa
    67981 aatgtcatgt gctttcttcg cgtcatcaac gatgataatg gcttagcaat tggtgcccgt
    68041 catattacag tctctacctc agggttagct cacaagattc gggattttgc aaacgaggga
    68101 gtacaggtta atttagcagt ctcgttgcat gcaccaaata atgatttacg ttcaagtatt
    68161 atgcgagtaa atcgctcttt tccgctggaa aagctctttt cagctataga atactatatt
    68221 gaaaaaacga atcgtcgtgt cacttttgaa tacattatgc taaatgaagt taacgatagc
    68281 attaagcaag ctcaagaact agcagactta actaaaacta ttcgtaagtt atcttatgtt
    68341 aacttgattc cgtataatcc tgtttcagaa catgatcagt atagtagaag tcctaaagag
    68401 cgagttctag cgttttatga tgtgctaaag aaaaatggag ttaactgtgt ggtgcgtcaa
    68461 gagcacggaa cagatattga tgcagcctgt ggccagttac gttctaaaac gatgaaaaaa
    68521 gatcgcgaaa aggttacagc gacaaaataa agtccaaaaa atatctttga ttgacaatgc
    68581 ttgatgacaa aatattccta gttactaaaa tgactaggtt ttttatctgg cctaaaaatg
    68641 ctctagaagc acaatccaaa ataatccaaa actaagataa ggaataaaag gtatgcgctt
    68701 gatgcctaat agtaagcaag cagtaatacc tgctaaacta gcaagttgaa ttagccaaat
    68761 caacgacgtt agatccaata ctaaagctaa gctagcaagg tagaaaaaat cgcctgctcc
    68821 aattgaaaaa ggtcttaaat gagctaataa acctagtagc agtaatatca atgataaata
    68881 attgatcgaa taaaacagga gtagacttac aaagctaaaa agccacaaga taaaagggta
    68941 ttcttgagaa cgccaatcaa ataaactaaa taataaagaa aagagtaaca agtaacagta
    69001 actagcacta acccaatgta ccatactagc ccataagata attattagac ttatctctaa
    69061 gctaaagaag attttttgac tagttataaa atggttttgg agctgccgaa aaacgcgttt
    69121 ggcaaaagtt agttggtcac aaacaatgac agtctgttta cttagctgtt cttgaccatt
    69181 atcaggaaaa taaagtagta aacagtaaaa aagatgggtc aataagatgc ccgaacatat
    69241 actaaaaaaa gctatcatac ttatttattc gaaaagaaat caaatacttg caatctttcc
    69301 ttaatcattg tagaatatag atataaaacg ataatgattc taattaagtg tctaatcatc
    69361 caattaggat tattccgtta ttgtcgaata ggattaggtc cttaaccctt tcttatgttt
    69421 atcacgttag ggttagttcc ccctccattc ttgcccttta agctgaaaag taaggagatg
    69481 ttattatgac aaacacactc gttgaaaata tttatgcttc agtaactcac aatatttcta
    69541 aaaaagaagc atcaaaaaat gaaaaaacta aagctgtttt aaaccaagct gtcgctgact
    69601 tatctgtggc tgcatctatt gtgcaccaag tacactggta tatgcgtggt ccaggtttct
    69661 tgtaccttca ccccaaaatg gatgaattac ttgatagctt gaatgctaat ttagatgaaa
    69721 tgagcgagcg tttgatcact attggcggag cgccttattc taccctagct gagttttcta
    69781 aacactctaa attggacgaa gcaaaaggta cttacgataa aacagttgct cagcatttag
    69841 caagattggt cgaagtttac ctttacctca gcagccttta ccaagttggt ttggatatta
    69901 ccgatgaaga aggcgatgct ggaacaaacg atttgtttac agcagctaag acagaggctg
    69961 aaaaaaccat ttggatgctc caagcagagc gtggacaagg cccagcactc taattgatta
    70021 tgccttagga taaaagaagt caatgataaa attggcttct tttttatgga atcatcgatt
    70081 cattttcaga aacatagaaa gcgattccat aattgtcttg aaatctgccg tagaatttgc
    70141 taaaatctac ttatatgaaa acactatatg atgtgcaaca attgctaaaa aactttggca
    70201 tttttgttta ccttggcaaa cgtctttatg atattgaaat gatgaagatt gaacttcagc
    70261 gtctctatga tagcggctta ttggataaga gggattactt aaatgcggag ttaattttgc
    70321 gacgtgagca tagattagaa ttggaaaaag aaggatagac aaatgagtca aaaattactg
    70381 gggattgatt taggtggtac caccattaaa tttggaattt taacagcagc aggagaagtc
    70441 caagaaaaat gggcaattga gactaatatt ttagaaggag gcaaacatat tgttcctgat
    70501 atcatcgctt ccatcaaaca tcgcttagac ttgtatggtc taagcagtgc tgattttgtg
    70561 ggaattggta tgggatcacc aggagcggtt gaccgtgata ctaatacagt tactggggca
    70621 ttcaacctta attggaaaga aacccaagaa gtcggttccg ttgttgaaaa agaattgggc
    70681 attccttttg ccattgacaa tgatgccaat gtggctgccc ttggtgaacg ttgggtaggt
    70741 gctggtgaaa ataacccaga tgtcgtcttc atgacacttg gaacaggtgt cggtggaggc
    70801 attattgctg atggtaactt gattcatggt gttgcaggag caggtggtga aatcggccac
    70861 atgattgttg agccagaaaa tggctttgct tgtacttgtg gctcacacgg ctgtttggaa
    70921 acagtagctt cagcaacagg agttgtcaaa gtggcacgtt tactggcaga agcctacgaa
    70981 ggggattcag ccatcaaagc agctattgac aatggtgaag gtgttaccag taaagacatt
    71041 ttcatggcgg ctgaagcagg ggattccttt gcttattctg ttgtggaaaa ggttggttac
    71101 taccttggcc ttgcttcagc aaatatttcc aatatcttga atccagactc agtggttatc
    71161 ggtgggggtg tgtcagcagc aggagaattt ctacgctcac gtattgaaaa atactttgtg
    71221 accttcactt tcccacaagt gaggtattca actaaaatta agattgcaga gcttggcaat
    71281 gatgctggaa ttatcggtgc agctagcctt gctcgacaat ttatcacaaa ataggagggg
    71341 gatatgtctc caatcacact tatcttatgg ttacttcttg tcggcattgt tggttattat
    71401 acatggaact atttctcttt tcgaaaaatg gcaaagcagg ttgataacga gacttttaaa
    71461 gacgtgatgc gtcaaggtca attgattgat ttacgagagc cagcggcttt tagaactaag
    71521 catattttag gagctcgaaa ttttccagcg caacaatttg atgctgctat taagggacta
    71581 cgcaaggaca aacctgttct tatttacgaa aatatgcatc cccagtaccg tgtgcctgcg
    71641 gtcaaaaaac ttaaaaaagc tggctttgaa gacgtttatg tcttaaaaga cggtattgat
    71701 tattgggatg gcaaagttaa acaaacaacc tagttaagag taacgtggag ttaaggggaa
    71761 taaagacagt cactgtctca aaaaccttaa ttcctttttt tgctgtatcc agacttgctg
    71821 aaagtctgaa aacatttaca attgattaaa accagttttt taaaacattt tgtgttatac
    71881 ttatctagtt aaaatatatt tacttagagg aacaaatgac taacttaaga aacgatatcc
    71941 gtaacgtagc gattattgcc cacgttgacc acggaaaaac aacacttgta gatgaattat
    72001 taaaacaatc ccatactctt gatgagcgta aagagctcca agagcgtgcc atggattcca
    72061 atgaccttga aaaagaacgt gggattacaa tccttgcgaa aaatacggca gtagcctata
    72121 acgatgttcg tattaacatc atggataccc caggacacgc ggactttggt ggtgaagttg
    72181 aacgtatcat gaaaatggtt gacggggttg ttcttgttgt ggatgcctac gaaggaacaa
    72241 tgccccagac gcgtttcgta ttgaaaaaag cacttgagca aaaccttatc ccaatcgttg
    72301 tggtgaacaa gattgacaaa ccttcagctc gtccagcaga agttgtagat gaagtgcttg
    72361 aattattcat cgaacttggt gccgatgatg agcaattgga attcccagtt gtttacgcat
    72421 cagctattaa tggcacatca tcattatcag atgatcctgc tgaccaagag catactatgg
    72481 cacctatctt tgatacgatt attgatcata ttccagcgcc agttgataat tcagatgagc
    72541 ctttgcaatt ccaagtgtca cttttggact acaacgattt cgtaggtcgt atcggtatcg
    72601 gtcgtgtttt ccgtggtact gttaaagttg gtgaccaagt aactctttca aaacttgatg
    72661 gtaccactaa aaacttccgt gttacaaaac tgtttggttt cttcggtttg gaacgtcgtg
    72721 aaattcaaga agctaaagca ggtgacttga ttgctgtttc aggtatggaa gatatctttg
    72781 ttggagaaac cattacacca actgactgtg tggaagctct gccaattctt cgtattgatg
    72841 agccaacgct tcagatgact ttcttggtca ataactctcc ttttgcaggt cgtgaaggta
    72901 aatggatcac gtcacgtaag gttgaagaac gtcttttagc agaattgcaa acagacgtgt
    72961 cacttcgtgt tgacccaaca gattcgccag ataagtggac ggtttcaggg cgtggagaat
    73021 tgcacttgtc aattcttatc gaaaccatgc gccgtgaagg ctatgaactt caagtatcac
    73081 gtccagaagt tatcatcaaa gaaattgatg gtgtcaaatg tgaaccgttt gagcgtgttc
    73141 aaattgatac accagaagaa tatcagggtg caatcatcca gtctctttca gaacgtaaag
    73201 gggatatgct tgatatgcag atggttggta atggtcaaac gcgtttgatt ttcttgattc
    73261 ctgcacgtgg tttgattggt tattcaacag agtttctttc aatgacacgt ggatatggta
    73321 tcatgaatca tacttttgat cagtatctac cggttgttca aggagaaatt ggtggtcgtc
    73381 atcgtggtgc cttggtttct attgaaaatg ggaaagcaac gacatattca atcatgcgta
    73441 ttgaagaacg tggaactatc tttgtcaacc caggtacaga agtttacgaa gggatgattg
    73501 ttggtgaaaa ctcacgtgat aacgaccttg gtgttaacat tacaacagct aagcaaatga
    73561 caaatgtccg ttcagcgact aaagatcaaa ctgcagttat caagacgcct cgtatcctaa
    73621 cgcttgaaga atcattagag ttcttgaatg acgacgaata catggaagta acgccagaat
    73681 ctatccgctt gcgtaaacaa atcttgaata aagctgcgcg tgataaagct aataaaaaga
    73741 aaaaatcagc cgaat
//
LOCUS       DAUCXI010000004        67937 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.004, whole genome shotgun sequence.
ACCESSION   DAUCXI010000004 DAUCXI010000000
VERSION     DAUCXI010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67937
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.004"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            236..907
                     /locus_tag="VGY43_000225"
     CDS             236..907
                     /locus_tag="VGY43_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEQ4301448.1"
                     /translation="MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSRRFLLLYVL
                     SGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVL
                     VLGFL"
     gene            complement(1006..1905)
                     /gene="galU"
                     /locus_tag="VGY43_000226"
     CDS             complement(1006..1905)
                     /gene="galU"
                     /locus_tag="VGY43_000226"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEQ4301449.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(1938..2954)
                     /locus_tag="VGY43_000227"
     CDS             complement(1938..2954)
                     /locus_tag="VGY43_000227"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ4301450.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     RNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            3252..3701
                     /locus_tag="VGY43_000228"
     CDS             3252..3701
                     /locus_tag="VGY43_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ4301451.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            3694..5400
                     /locus_tag="VGY43_000229"
     CDS             3694..5400
                     /locus_tag="VGY43_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301452.1"
                     /translation="MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPFLFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIEPGQMVGIVGATGSGKSTLVQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     DSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            5403..7187
                     /locus_tag="VGY43_000230"
     CDS             5403..7187
                     /locus_tag="VGY43_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301453.1"
                     /translation="MKTARFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLVQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTMTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAVVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTIGQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNVFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            7305..8072
                     /locus_tag="VGY43_000231"
     CDS             7305..8072
                     /locus_tag="VGY43_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEQ4301454.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWAKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            8182..8628
                     /locus_tag="VGY43_000232"
     CDS             8182..8628
                     /locus_tag="VGY43_000232"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEQ4301455.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            8709..10070
                     /gene="radA"
                     /locus_tag="VGY43_000233"
     CDS             8709..10070
                     /gene="radA"
                     /locus_tag="VGY43_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEQ4301456.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKA
                     VFS"
     gene            10259..10756
                     /locus_tag="VGY43_000234"
     CDS             10259..10756
                     /locus_tag="VGY43_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEQ4301457.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVRKDMAKLRASSLIPDDVVINGAVYDVDTGKM
                     TQVME"
     gene            10887..11597
                     /locus_tag="VGY43_000235"
     CDS             10887..11597
                     /locus_tag="VGY43_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEQ4301458.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            11779..13224
                     /locus_tag="VGY43_000236"
     CDS             11779..13224
                     /locus_tag="VGY43_000236"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEQ4301459.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDKLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYISEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            13618..14965
                     /locus_tag="VGY43_000237"
                     /pseudo
     CDS             13618..14965
                     /locus_tag="VGY43_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            14962..16245
                     /locus_tag="VGY43_000238"
     CDS             14962..16245
                     /locus_tag="VGY43_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ4301460.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSVIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSATSMMRTNYEISSLDNIKETVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            16249..16989
                     /locus_tag="VGY43_000239"
     CDS             16249..16989
                     /locus_tag="VGY43_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4301461.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            17529..17888
                     /gene="rnpA"
                     /locus_tag="VGY43_000240"
     CDS             17529..17888
                     /gene="rnpA"
                     /locus_tag="VGY43_000240"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEQ4301462.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            17854..18681
                     /locus_tag="VGY43_000241"
     CDS             17854..18681
                     /locus_tag="VGY43_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEQ4301463.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIIFMGFNL
                     ASGVVLYWTVSNAFQVLQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            18693..19607
                     /locus_tag="VGY43_000242"
     CDS             18693..19607
                     /locus_tag="VGY43_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEQ4301464.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINQKNAPVVNSADVEPEEIKATQRLEAED
                     TKVVPLMSEDSPAQTPSNLAETVTERKAQQPSIPVEESEVPQDPGNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKIVH
                     KTVSSIEGVDSYSEGNDPNRYVVVSLQR"
     gene            19922..20056
                     /gene="rpmH"
                     /locus_tag="VGY43_000243"
     CDS             19922..20056
                     /gene="rpmH"
                     /locus_tag="VGY43_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEQ4301465.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
     gene            20330..21034
                     /locus_tag="VGY43_000244"
     CDS             20330..21034
                     /locus_tag="VGY43_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEQ4301466.1"
                     /translation="MPDKPTKEKLMEQLKGEIIVSCQALPGEPLYSETGGIMPLLAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMTEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVIGGAI
                     TRPKEIAERFIEALKS"
     gene            21083..22402
                     /locus_tag="VGY43_000245"
     CDS             21083..22402
                     /locus_tag="VGY43_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ4301467.1"
                     /translation="MNMKKFASLAMLGASVLGLAACGGKSQKEASESKSDAAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKANPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTKEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKKFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMKKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAVSNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            22507..23394
                     /locus_tag="VGY43_000246"
     CDS             22507..23394
                     /locus_tag="VGY43_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ4301468.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTDFTFVGFANYARMFQDPIFMKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            23407..24237
                     /locus_tag="VGY43_000247"
     CDS             23407..24237
                     /locus_tag="VGY43_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEQ4301469.1"
                     /translation="MKKKKLTASDVLTTVILCILTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            24257..24712
                     /locus_tag="VGY43_000248"
     CDS             24257..24712
                     /locus_tag="VGY43_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEQ4301470.1"
                     /translation="MIYDRLKNISRYRGIHPHLDAAITFLQTTDLRQLAEGKYPILGE
                     KVFAVIQRNQLSKADNSLLEYHKRYADCHLLLAGNECIRYGIGNQAEVVPFEQEADIG
                     FVTCDRTYDLDLVDDSFAYFFPNEPHQPNNFNQAGEAVTKCLIKVLMAD"
     gene            24756..25418
                     /locus_tag="VGY43_000249"
     CDS             24756..25418
                     /locus_tag="VGY43_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEQ4301471.1"
                     /translation="MTSKKQGLLHSLFNLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLVTTYSSHFKHYFKSGMRLGLIELLIMSICVLDLF
                     LIRNQSGLVFQGFKVLCIAVLFLVVILFLYAYPQAVRKELSLSTLFKRTFLLAGLFFP
                     WSFAFLALICLTIFSLQLSLLTLFGGVSLLAIIGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            25430..26344
                     /locus_tag="VGY43_000250"
     CDS             25430..26344
                     /locus_tag="VGY43_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEQ4301472.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGAISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIVDKDLEKAKTFQYTINEIIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLAELVEEDRVICQRAAALINQAKETF"
     gene            26366..27304
                     /locus_tag="VGY43_000251"
     CDS             26366..27304
                     /locus_tag="VGY43_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ4301473.1"
                     /translation="MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKNEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITPEKIENNLASS"
     gene            complement(27415..28245)
                     /locus_tag="VGY43_000252"
     CDS             complement(27415..28245)
                     /locus_tag="VGY43_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEQ4301474.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDASERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNDNCLVFGFSLSGKTNSVITALHQASQRGAKTVLLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNDL
                     "
     gene            28530..29321
                     /locus_tag="VGY43_000253"
     CDS             28530..29321
                     /locus_tag="VGY43_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEQ4301475.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVV
                     GFDQATISGALALADQYPNVYATIGWHPTEAGSYSEAVEESIVSQLSHPKVIALGEIG
                     LDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEIIKAAGVGPRGGIM
                     HSYSGSLEMARRFVDLGMMISFSGVVTFKKALDIQEAAQHLPLDKIVVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD"
     gene            29293..29883
                     /gene="rnmV"
                     /locus_tag="VGY43_000254"
     CDS             29293..29883
                     /gene="rnmV"
                     /locus_tag="VGY43_000254"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEQ4301476.1"
                     /translation="MQRGYSSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEATPSSKS
                     KGRSLGVEHANFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMEAYEE"
     gene            30010..30882
                     /gene="rsmA"
                     /locus_tag="VGY43_000255"
     CDS             30010..30882
                     /gene="rsmA"
                     /locus_tag="VGY43_000255"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEQ4301477.1"
                     /translation="MRIADYSVTKTVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVED
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKAKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            31306..32178
                     /gene="rsgA"
                     /locus_tag="VGY43_000256"
     CDS             31306..32178
                     /gene="rsgA"
                     /locus_tag="VGY43_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEQ4301478.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYNFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALEMGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            32188..32850
                     /locus_tag="VGY43_000257"
     CDS             32188..32850
                     /locus_tag="VGY43_000257"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEQ4301479.1"
                     /translation="MSTLKIAPSILAADYANFASELARIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGADIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            32843..33475
                     /locus_tag="VGY43_000258"
     CDS             32843..33475
                     /locus_tag="VGY43_000258"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEQ4301480.1"
                     /translation="MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVSQKAFTDIKEKAELLITANPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            33477..34748
                     /locus_tag="VGY43_000259"
     CDS             33477..34748
                     /locus_tag="VGY43_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEQ4301481.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     MTYQLDTANKQQLLELTQLMNRQQADLYQQLTDIRDVLHRSLSDSRDRSDKRLEKINQ
                     QVNQSLKNMQESNEKRLEEMRQIVEEKLEETLKNRLHASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNAAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQATKSLLNMPLLEEENNEN"
     gene            34738..35676
                     /locus_tag="VGY43_000260"
     CDS             34738..35676
                     /locus_tag="VGY43_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEQ4301482.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVEEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            35943..36782
                     /gene="purR"
                     /locus_tag="VGY43_000261"
     CDS             35943..36782
                     /gene="purR"
                     /locus_tag="VGY43_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEQ4301483.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            36773..39394
                     /locus_tag="VGY43_000262"
     CDS             36773..39394
                     /locus_tag="VGY43_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEQ4301484.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRASEET
                     KASNTHDDSLPKPETIQEAKATIEAVEKTLSQQKTKLTELATALTKTTAEINHLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANDNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKA
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKRNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEALAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQEALAALQAKQSSLEATIATTEHQLTLLKTLANEKEYRHLDED
                     IATVPDLQVAPPLTGVKPLSYSKIDTTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESR"
     gene            39602..40015
                     /gene="rpsL"
                     /locus_tag="VGY43_000263"
     CDS             39602..40015
                     /gene="rpsL"
                     /locus_tag="VGY43_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEQ4301485.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            40036..40506
                     /gene="rpsG"
                     /locus_tag="VGY43_000264"
     CDS             40036..40506
                     /gene="rpsG"
                     /locus_tag="VGY43_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEQ4301486.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFSAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            40990..43068
                     /gene="fusA"
                     /locus_tag="VGY43_000265"
     CDS             40990..43068
                     /gene="fusA"
                     /locus_tag="VGY43_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEQ4301487.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            43416..44426
                     /gene="gap"
                     /locus_tag="VGY43_000266"
     CDS             43416..44426
                     /gene="gap"
                     /locus_tag="VGY43_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEQ4301488.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(44652..44768)
                     /locus_tag="VGY43_000267"
     CDS             complement(44652..44768)
                     /locus_tag="VGY43_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEQ4301489.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(44910..45650)
                     /locus_tag="VGY43_000268"
     CDS             complement(44910..45650)
                     /locus_tag="VGY43_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301490.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRIIFMDKGL
                     IAEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            complement(45643..47211)
                     /locus_tag="VGY43_000269"
     CDS             complement(45643..47211)
                     /locus_tag="VGY43_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ4301491.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKVAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYAEAKSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKAS
                     FLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRHIERRFDADTYT
                     TGANQMQIAEVSNV"
     gene            47409..49334
                     /locus_tag="VGY43_000270"
     CDS             47409..49334
                     /locus_tag="VGY43_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEQ4301492.1"
                     /translation="MKKILMTLVLCFSLLGIRIKAADVDYSITNYEGQLLLSKENTAR
                     FEQKVTYQFDTSYNGQYISLGRTGHLPAGFAIDQKPKVEVYQNGQQVPVSQEFSDLGD
                     GYRLKLYNAGQAGDKVDVKVIWQLHHLLTAYQDVAELNWTPISDWDKILEKVSLTVTT
                     PTDIQDSNLWAHRGYYQKKPQVLKEGNSRYQINAKNVSGQLELHAYWDKKALLGEEPV
                     DVSTSKKNKIVALETKISRRRALLQLLFGKVIPLVEVGFLLWQLIQFTRLKKQFNRYH
                     LANHTDHSYEVPEDLSPLVLAQAIYGQSFAYLSPTASESQKLLIPKGVTFEALVQATL
                     LDLIDQKVLLLTKEEGKAYLEISQLDRVTDEEAAFLDMAFGNKVTLPVDQLFSQYHYD
                     ADTIKQLKKTYKGKKLEQEVRQSSEQVIKAMKKASAAITNNVLETIKKLNLPDTYRQM
                     TPAEKRKSNSVQGLGCLLLILNSGLLIYLAIKESGLALIYLALMVLTMCLGFYISLKL
                     DQYKKLGIETPEGGVRLHQWQSFKNMIRDIDKFEDVAIEGLVVWNRVLVYATLFGYAK
                     KVERYLKVHRIALPEVYQAVRPGELSMVMYATTPTFVSSLSSATTSSNFSVSSGGGIS
                     GGGGFSGGGGGGGGGAF"
     gene            49400..50239
                     /locus_tag="VGY43_000271"
     CDS             49400..50239
                     /locus_tag="VGY43_000271"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEQ4301493.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKQNAQQEPAVTDLARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTHYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            50385..51146
                     /gene="mecA"
                     /locus_tag="VGY43_000272"
     CDS             50385..51146
                     /gene="mecA"
                     /locus_tag="VGY43_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEQ4301494.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAVDPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            51153..52322
                     /locus_tag="VGY43_000273"
     CDS             51153..52322
                     /locus_tag="VGY43_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEQ4301495.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLIAAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLEIWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            52444..53214
                     /gene="sufC"
                     /locus_tag="VGY43_000274"
     CDS             52444..53214
                     /gene="sufC"
                     /locus_tag="VGY43_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEQ4301496.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            53309..54571
                     /gene="sufD"
                     /locus_tag="VGY43_000275"
     CDS             53309..54571
                     /gene="sufD"
                     /locus_tag="VGY43_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEQ4301497.1"
                     /translation="MTKEKLVAFSQVHAEPAWLQERRLAALEAIPELELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGIVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKTSANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKGAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLNQETAERLVIRGF
                     LGAVIAEIPIPSVRQEIIKVLDEKLLNR"
     gene            54602..55828
                     /locus_tag="VGY43_000276"
     CDS             54602..55828
                     /locus_tag="VGY43_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ4301498.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATHKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMIDFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            55815..56294
                     /locus_tag="VGY43_000277"
     CDS             55815..56294
                     /locus_tag="VGY43_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEQ4301499.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            56287..57705
                     /gene="sufB"
                     /locus_tag="VGY43_000278"
     CDS             56287..57705
                     /gene="sufB"
                     /locus_tag="VGY43_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEQ4301500.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(57857..59038)
                     /locus_tag="VGY43_000279"
     CDS             complement(57857..59038)
                     /locus_tag="VGY43_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ4301501.1"
                     /translation="MTKRIILTIFTFICFSMMPLVHAEDVMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRINA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGIKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSPKQQHFKATKKQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(59206..60438)
                     /locus_tag="VGY43_000280"
     CDS             complement(59206..60438)
                     /locus_tag="VGY43_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ4301502.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDAKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFDGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLSVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            60769..62739
                     /locus_tag="VGY43_000281"
     CDS             60769..62739
                     /locus_tag="VGY43_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ4301503.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     AKQYEKAKEKWMKAKAKSNAKYAEKLADHVEK"
     gene            62804..64306
                     /locus_tag="VGY43_000282"
     CDS             62804..64306
                     /locus_tag="VGY43_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4301504.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSFIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAVYEKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTATMTFMLALPSIAVI
                     YVVRFLGGMVGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            64306..65232
                     /locus_tag="VGY43_000283"
     CDS             64306..65232
                     /locus_tag="VGY43_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4301505.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            65241..66311
                     /locus_tag="VGY43_000284"
     CDS             65241..66311
                     /locus_tag="VGY43_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301506.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQGLHQKILRKMSQQEEGNV"
     gene            66304..67227
                     /locus_tag="VGY43_000285"
     CDS             66304..67227
                     /locus_tag="VGY43_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301507.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(67265..67354)
                     /locus_tag="VGY43_000286"
     CDS             complement(67265..67354)
                     /locus_tag="VGY43_000286"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ4301508.1"
                     /translation="MIIDYCNNKRIKIKRKGLSPLQYKTKSFT"
BASE COUNT        20594 a        12334 c        14349 g        20660 t
ORIGIN      
        1 tagtttcttg tcagtcttga acctttttcc taatttatgg tatgataaga agatgatgaa
       61 aaaagagatt ctcaaagaac tcttctagtc tttacgaact atggatgtag acttaaaacg
      121 tcaaaatgat caagctttat tagtggatgt tgttagcaat caagcttatc agcgggccaa
      181 tacgattgcc aaatcaaacg atttatgata ttgctgttta ggaggtttat cttagatgac
      241 acggttatta aaacgatatc ctattactat tttcctttta gggttaacag gcttaatttt
      301 tatagcaatg caagtggtat atggacattt agcaactggt gctcaagcta tttatcaagt
      361 tggaggtatg tttggattac tagtaaaagc aatgccagat cagttgtggc gattggtgac
      421 tccgatattt attcatatcg gctttggtca tttttttgtc aatggattaa cactatattt
      481 tgttggtcaa atcgtcgaag acctctgggg ttcacgccgt tttttattac tttatgtttt
      541 atcaggtgtt atgggcaatg cctttacttt ttggttgact cctgaaacag tagctgcagg
      601 agcatcgacg tcgttatttg gactttttgc tgctattgta gtattgagtt ttttgggtaa
      661 gaaccaagcg ttgaaagatt tgggcaagtc ataccagacg ttaattgtag tcaatttact
      721 gatgaatctt tttatgccaa acgtgagtat ggcaggccat attggcggtg tcgtgggtgg
      781 tgcgttactg agtatagttt ttccaactaa gatgagagtg ataacagtga agaaaaccaa
      841 gcgaatgttg gctttagtga gctatggtat tattttggtt ggtgtgttag tgcttgggtt
      901 tttataaaaa taagtgagtg gttagcactg ttacttctca gatggctagt aggatgaaac
      961 gactcaaaaa ccataaaaat aaggagggat tttccctcct tatttttatg gttttgtttt
     1021 ctctagtgct ttgcccagtt ggatgatgta ggctttcaag tcatctttga cttgagggtg
     1081 tttcagggca taatccaaag aagttttcat aaacccaaat ttatcgccaa catcatagcg
     1141 tttcccttta aactcacgag caaagacacg ctgtgtctta ttgagggtat caatagcatc
     1201 agtcagttga acttcattgc ctgcaccagg ttcttgtttt tctaaaatac taaaaatttc
     1261 tggtgtgagc aagtaacgtc caataattgc caaatcacta ggtgcatctt gaggttgtgg
     1321 tttttcaaca aaagtatcca cactatagag tccttttact gcttttgctt gaggagcaat
     1381 gataccgtag ttagagacat cctcgtgagg aaccctcatg acggcaatag ttgcagcatg
     1441 agtttcttca tagtcatcga tcaattgttt ggttaatggt tttacatttg gatttgtaat
     1501 atccatcaga tcatcaccta gcatgacaac aaaaggttca ttgccaacaa aggtctttgc
     1561 ttgaagaact gcgtctccta atcctcttgg atgactctgt cgaataaagt gaagattaat
     1621 agaagtggtc tcgtctacta actttagaag ttcgattttt cctttagcct gtaaattata
     1681 ttctaattca aaattagaat caaaatgatc ttctatggag cgtttggatt ttccagtaac
     1741 gataagaatt tcttcgatac ctgattttag agcttcttca acgataaatt gaatagttgg
     1801 tttatcaaca ataggtagca tctccttggc aagggccttg gttgcaggta aaaaacgtgt
     1861 gcctaaacct gctgcgggaa taatagcttt tctgactttg gtcatcagca cctcctctta
     1921 ttttagtgac gtatggctta atgccattca ttttcagaac gaaattcatt tgacatcatg
     1981 ccgaggatgc tttctttgat atcagcgccc tcgtagatgg acttataaat agctgttgta
     2041 attggcatgt aaactccgag gtcttgggca atttcatagg ctaccttagt tgttgcgatg
     2101 ccttcgataa ccatacccat gttgcgttca atatcttcta atttttcacc acgtccaagg
     2161 gcagctccag cccgccagtt acgtgaatgg acagaagtac ctgttacaat tagatcacca
     2221 acaccagata acccactgta ggttaacggg tcagcaccaa gcttgacgcc tagacgggtg
     2281 atttcagcta acccacgagt aattaccgct gctttggcat tatctccata cccaagtcca
     2341 tggagagctc ctgctccaac agcaataatg tttttgaggg caccagctgt ttcaactccg
     2401 atgacgtcgg tattggtata aagtcggaag tagtggttac taaagaggga ctgaacatac
     2461 tttgcagctt caatatcttt tgaggctgcc gtgatgagag taatatcgcg aacgatagtt
     2521 tcttcagcat gactaggacc tgatacaacg accacttcgc tacgaaaatg agctggaatt
     2581 tcttcttcta ggatagttga taaacgttcg tgggtctctg gttctagacc ttttgaggca
     2641 tgcatgacca ctactttatg atctaaaatg gcggcaactt gtctagcaac taatcgtgtt
     2701 actttagttg gcacaacaaa aagcaccgca tcaacatctg atagggcttg acctaaatca
     2761 agagttgccg taatgttttt gtctaacaca atgtctttga agtagtgtct attggtatgc
     2821 ttggtattta tctcttcaat ttgatcagga atatttcccc ataaacggac gtcatggcca
     2881 ttgtcattaa gaacctgaga aagagcagtt ccccaagaac caggtcctaa aatagctact
     2941 ttttgttttg tcattctaaa ttctccttca agagctagtc actctattat aacataacac
     3001 cttgattagc tctattagaa aaggtatatg gtcttggcta ataaggcgtt ctcaagagag
     3061 ctagctatat taataatgtt gtttaataag cttcatcagg tgagctgttg tcatggcttt
     3121 gccttgttct ttttagttat ttaagttcgg aaacttattt ttaaaaataa agatatttta
     3181 attgacaata gttatctaga gaactaaaat acttatcata gaaactatta aggaaaagaa
     3241 ggagggaaga gatgtcacaa gtgataggtg atttacgtga attgatacat caaatcgaac
     3301 aaattagtga tgagattgca aaaaaatatg atgtagagca tctagcaggt cctcaaggtt
     3361 atgttcttgt ttttttagct aaacaccaaa atcaagaaat atttgtcaaa gatattgaaa
     3421 aacaacttcg tatctcaaag tcagttgcta gtcatttagt gaaacgtatg gtcaaaaatg
     3481 ggtttatcaa tgtgatgcct tcccaagtgg ataagcgtta taagcaagta gtgttagcgc
     3541 aggttggtag agataaattg cctttgttgc gggagtgtcg taaggatatc gagcactatt
     3601 ttttaaaaga aattacaaaa gaagagttgc tgacagcgaa aaaagtaatt gaacagctca
     3661 agcaaaatat gctaacttat aaaggagaca acgatgctta aagacgcaat cttacgttat
     3721 aaatggtatg ctttaggctc attttttatg gttattgggg ttgttgcaag tagtctcttg
     3781 caaccacatt atcttaaatc tgtgctaagc gctgttattc aaaataatca agagaaaatt
     3841 tatgaggttg ggaaaccatt acttattatt gcccttttag ggttaatgtc tggagcgatt
     3901 aatacggttt tagctgctaa aatagctcaa ggtgtatctg ctgatatgag ggagaagacc
     3961 tttcgaaaaa tccaagactt ttcatatgcc aatattgaag cttttaatgc tggtaatctt
     4021 gtggttaggc taactaatga tatcaatcaa atccaaagtt tagtcatgat gatgtttcaa
     4081 attctctttc gtttgccgtt cctttttatt ggcgcgttta tcatggcagt tcagacattc
     4141 cctcaattat ggtgggtcat tgttgtaatg gttatcttaa ttgccctcat catgggtttg
     4201 gtgatgcgtc aaatgggtcc tcgttttggt aaatttcaac ggttaatgga taagattaat
     4261 cgcatcgcta aggaaaatct ccgtggcgtt cgcgtggtta aatcatttgt acaagaacaa
     4321 caacaataca ctaaatttaa agaaacgtcc aatgatcttt tggcgttaaa tttatctatt
     4381 ggttatggtt tttcactaat gcagccggct ttaatgttgg tgtcttattt ggcagtttat
     4441 gtttctataa atgttgtttc gaccatggtc gaaacagatc caacagtgat tgggaatatt
     4501 gcctctttca tgacttatat gatgcaaatt atgttttcaa ttattgtggt tggttccatg
     4561 gggatgcaag ttagtcgtgc ttttgtttct atggctagaa ttaggcaaat attgtctaca
     4621 gaacctgcca tgacatttga aaatgaaaag gaagaaacca tctcaggaag cattgtattt
     4681 gacgatgtta gttttacata tcctaatgat gatgagccaa ccttgaagca catttctttt
     4741 gctattgaac ctgggcaaat ggtcggcatc gttggtgcaa caggatctgg gaaatcaacg
     4801 cttgtacagc tcatccctcg cttatttgat cctcaagatg gccaaatttt gttaggagga
     4861 aagccgatta aaaccctaag tcaaacaacc ctgcgccaat cggtttccat cgtgttgcaa
     4921 aaggctattc tcttttcagg aacgatagct gataaccttc gccaaggctc agcaaaagct
     4981 gatattgatg ctatgcaaaa agccgctcaa atcgcgcaag caaaagaatt tattgatcgc
     5041 atggatagcc gttatgagag ccaagttgaa gagcgaggta gtaacttgtc tggcggacaa
     5101 aagcaacgtc tgtctattgc acgtggtgtc attaatcatc ccaaaatcct tatattagac
     5161 gattccactt cagctcttga tgcaaaatct gaaaaacgcg ttcaagaagc cttaagtcat
     5221 aaattagaag gtacaactac agttattgtt gctcaaaaaa tttcatcggt agttaaggca
     5281 gataagatct tagtccttga ccaaggacag ttaattggag aaggaacaca cgcagagttg
     5341 gtggctaata atgcgattta tcgtgaaatt tatgagacac aaaaaggaag ggaggagtag
     5401 tgatgaaaac agcacgtttt ttctggtttt attttaaacg ctatcgtttc tcgtttactg
     5461 tcattgctgt tgccgttatc ttagcaactt atttacaagt aaaagctcct gtcttcttag
     5521 gggagtcctt gactgagttg ggaaaaatcg gtcaggctta ttacgttgct aagatgagtg
     5581 gtcagacaca ttttagccct gatttatcag cttttaatgc cgtgatgttt aagcttttga
     5641 tgacttattt ctttactgtt ttagctaatc taatatatag tttcttactc acacgtgttg
     5701 tctcacattc gaccaaccgc atgcgcaagg gcttgtttgg taaattagaa cgtttaaccg
     5761 tcgccttttt tgaccgccat aaagatgggg agattctttc tcgtttcacg agtgatttgg
     5821 ataatattca aaactcgctg aaccaatcct tggttcaagt ggtgactaat attgcccttt
     5881 acatcggcct ggtctggatg atgtttaggc aagatagccg tttagctttg ttaaccatcg
     5941 catcaacccc agttgctctc atttttttag tgattaacat ccgtttggca agaaaataca
     6001 ccaatatcca acagcaagaa gtcagtgctt taaatgcttt tatggatgaa accatttcag
     6061 gacaaaaggc tattattgta caaggtgtcc aagaagatac gatgacagcc tttttaaagc
     6121 ataatgaaag ggttcgacaa gccaccttca aacgccgtct gttctcagga caattatttc
     6181 cagtcatgaa tggaatgagc cttattaaca cggctgtcgt gatttttgtc ggttcaacaa
     6241 ttgtcctcag tgacaaatct atgccagcag cggcagcgct tggtttagtg gttacttttg
     6301 tacaatattc ccagcaatat taccaaccca tgatgcaaat cgcgtctagt tggggagaat
     6361 tgcagctggc ctttaccggt gctcaccgta ttcaagaaat gtttgatgaa accgaagaag
     6421 ttcgtccaca aaatgcacca gcgttcacca gcttaaaaga agcagtggcg attaaccacg
     6481 tcgattttgg gtatcttcct gggcaaaaag ttttatcaga tgtgtcaatc gttgcaccca
     6541 agggcaaaat gattgccgtg gttggaccga caggttctgg aaagaccact attatgaact
     6601 tgattaaccg tttctacgat gtggatgcag gttcgattac ctttgatggc cgtgatattc
     6661 gtgactacga tttggatagt cttcgtcaaa aggtagggat tgtgttgcaa gagtcagttc
     6721 ttttttcagg aaccattacg gataatattc gttttggtga tcagaccatt ggtcaagaca
     6781 tggttgaaac tgctgcgcgt gcgacccata ttcatgactt tatcatgtcc ttaccaaaag
     6841 ggtacaatac ctatgtctca gatgatgaca atgtcttttc aacaggtcaa aagcagttga
     6901 tttctattgc taggacgcta ctgactgacc ctgaagtgtt gattttggat gaggccactt
     6961 caaatgttga tacggttacc gaaagtaaaa ttcaacgggc catggaagct atcgtggcag
     7021 gtcgaactag ctttgtcatt gctcaccgcc tcaaaaccat tttaaatgca gatcacatta
     7081 ttgtgttgaa agatggcaag gtcattgagc aaggaaatca tcatgagcta ttgcatcaaa
     7141 aaggctttta tgccgaattg tatcacaatc aatttgtctt tgaatagatg gtatcagctc
     7201 cgcgtcttag cggagttttt tggtgaacaa taaagcagtc aagctttctt tcctgatatg
     7261 gtataatagc aagcaagaga aaaaacaatt agaaagtagc cacaatgatt gatttacaag
     7321 agattctcgc taacatgaat cccaatcaaa agataaatta tgacagggtc atgcaacaga
     7381 tggccaaggt ttgggctaag gaatccgtgc gtcccagtat tttaatgcat gtctgctgtg
     7441 ccccatgctc cacttacacc ctagaatacc tgacgcagtt tgctgacatt acggtttact
     7501 ttgccaattc taatattcac cctaaggacg aataccatcg cagagcctat gtgacacaac
     7561 agtttgtctc cgagttcaac gctaaaacag gcaacaccgt gcagtttctc gaagcggact
     7621 atgtccccaa tgagtacgtt cgacaagtgc gaggtttaga agaagaacca gaaggtgggg
     7681 accgttgccg tgtctgtttt gattaccgac tagacaagac cgctcaaaaa gcagtggaac
     7741 taggttttga ctactttgcc agtgccctaa ccatcagtcc tcataaaaat tcgcaaacca
     7801 ttaatgatgt gggcatcgat gtgcaaaagg tttacaccac caaatacctg ccaagtgatt
     7861 tcaagaaaaa caacggttat cgcagatccg ttgaaatgtg tgaggagtat gatatttacc
     7921 gtcaatgcta ttgtggctgt gtttatgctg ccaaaatgca aggtattgac ttggttcaag
     7981 tgaaaaaaga tgccaaagct tttatggcag acaaggattt ggataatgat ttcacccaca
     8041 tccgctttag ttatcgtggg gatgagatgt gatggcatga ttaaaagtgg tccgtttaaa
     8101 gttgaccgct tttttgctat tcttttacga atagtctata ataagaggat atgattgact
     8161 tgaaaggata tacctatcat aatgacaaaa attcgtggtt tcgagcttgt ttcaagcttt
     8221 actaatcctg atttactacc aaaacgtgag acgactcatg cagctggtta tgacctgtct
     8281 gttgctgagg ctgtaaccat tgccccaggg gagattaagt tggtaccaac aggggttaag
     8341 gcctatatgc aagatggtga ggtgctttac ctctatgatc gttcgtcaaa tccacgaaaa
     8401 aaagggatta tcctgattaa ttcagtaggt gtgattgatg cagattatta tggcaatgag
     8461 gctaatgaag gacatatttt tgcacaaatg caaaacatta cagatcaccc tgtgacatta
     8521 gctgtgggtg agaggatcgt tcagggtgtt tttatgcctt ttttaattgc tgatggtgac
     8581 caagccagag gtgaacgaac aggtggtttt ggttcgacag ggcagtaaag cgatttaaca
     8641 aaaatgctta tgacagcaga cctattcttt aagagtgggt ttgtcttgtc taggggaggg
     8701 agattactat ggcaaagaaa aaagcaacct ttatctgtca ggagtgtggc taccagtcgc
     8761 caaagtattt agggcgctgt ccaaattgct cggcctggtc ttcttttgtg gaagaagtag
     8821 aggtcaaaga agtcaaaaat gcccgtgtta gtctagctgg agaaaagtcc agaccggtta
     8881 aactaaaaga tgtggataat attagttatc acagaacaca gactgacatg tctgaattta
     8941 atagagttct tggagggggt gtggttcctg gaagcttgat tttaattggt ggtgatccag
     9001 gtattggaaa atccacctta ctcttgcagg tatctacgca gctcgctaat aagggaacgg
     9061 ttctctatgc gtctggggaa gaatcagcag agcagattaa actgcggagt gagcgtctgg
     9121 gtgatattga caatgaattt tacctctatg ccgaaaccaa tatgcaagct attcgcacag
     9181 aaattgaaaa tattaaacca gattttttaa ttattgactc cattcagacc atcatgagcc
     9241 ctgatattac aggtgttcaa ggatcagtca gtcaggtgag agaagtcact gcagaattga
     9301 tgcagcttgc aaagacgaac aacattgcaa cctttattgt gggtcatgtc accaaggaag
     9361 gaaccttggc tgggcctcgt atgttagaac acatggtgga taccgttctc tactttgaag
     9421 gggaaaggca tcacaccttt cgcattcttc gggctgtgaa aaaccgcttt ggctccacta
     9481 acgagattgg catctttgaa atgcagtctg gcggcttggt agaggtctta aatcctagtc
     9541 aagtcttttt agaggaacgc ttagatgggg caacaggatc ggctgtcgtt gtaacgatgg
     9601 aaggaagtcg tcctatctta gcagaggtgc aatctttagt gacaccaacc gtttttggca
     9661 atgccagacg aaccactacg ggacttgatt tcaatcgcgt aagcctaata atggcagttt
     9721 tagaaaagcg ttgtggttta ctcttacaaa atcaagatgc ctacctcaag tcggctggtg
     9781 gtgtcaaact agacgaacct gccattgatt tggcagtcgc tgtggctatc gcatccagtt
     9841 ataaggaaaa accaaccagc cctcaagaag ctttcttagg cgagatcggg ttaacaggtg
     9901 agattcggcg agtgacccgt attgagcaac ggattaatga agcagcaaag cttggcttta
     9961 ccaaggtcta tgctcctaaa aatgccttgc aaggcattga tatccctcaa ggtattgagg
    10021 ttgttggagt gactacggtt ggtcaggttt taaaggcagt ttttagctag aggatcagaa
    10081 actaagagca aatgaggagg aaatttgtca agaaagtatc ccaatcattt gtttttttaa
    10141 cttttcgaac gataccgacc gtctaagagg ttaatccagc tattttccat aaaagatgtt
    10201 aagataagac aaactaacag caaaaatagc tctgctgttt ctcaaaagga gtttattgat
    10261 gtcttatttt gaacatttta tggctgccaa tcaggcttat gtggccttgc atgggacagc
    10321 tcatttgccc ttaaaaccca agactaaagt agcgattgtg acttgtatgg attcacggct
    10381 acatgtggcc caagctctgg ggctggctct aggagatgct catattttaa ggaatgctgg
    10441 cggacgtgtc accgaagaca tgattcggtc gctggttatt tctcagcagc aaatgggaac
    10501 gcgagagatt gtggttctcc accatacaga ttgtggcgcg cagactttta ctaatgaagg
    10561 ctttgccaag catattcatg agcacttagg tgtggatgtt tcagggcaag atttccttcc
    10621 cttccaagat gtggaagaca gtgtccgcaa ggatatggct aagctaagag cctcctctct
    10681 tatccctgat gatgtcgtta ttaacggtgc cgtctacgat gtggatactg gaaagatgac
    10741 acaagtaatg gaatagttag tagccaagtt gcagagctga attcagctct tttttatttt
    10801 taaaaattat tgaaaatatt agacaaagaa atagggaagc gttataataa ttgtatcaag
    10861 ttattcatac aaacaaggag agtaagatgg tcgacaatag aatgagattt acgattgacc
    10921 aaaacatgca atttccacta gttgagattg atctggaaca tgggggatca gtttacttac
    10981 aacaaggaag tatggtttat catactgaga atgtaacctt gaataccaaa ttgaatggta
    11041 agggatctgg tttaggaaaa ttagttggag ccatcggccg ttccatggtt tctggtgaat
    11101 caatgttcat tacacaagct atgtcaaatg gagatggtaa attagcatta gcacccaata
    11161 caccaggaca gattgttgct ttagaactag gtgaaaaaca atatcgtcta aatgatggtg
    11221 cctttctagc cctagatggt tcagcacagt acaaaatgga acgtcaaaat attggaaaag
    11281 cactttttgg tggtcaaggc ggactttttg tcatgacaac tgaaggcctg ggtaccttac
    11341 ttgctaactc gtttggatct atcaagaaaa tcacacttga tggtggcaca atgactattg
    11401 ataatgccca tgttgtagca tggagcagag aacttgatta tgatattcat ttagaaaatg
    11461 gctttatgca gtcaattggt acaggtgaag gagttgttaa tacctttaga ggtcatggtg
    11521 agatttatat ccaaagtctt aaccttgagc aatttgctgg gactcttaaa cgttatctac
    11581 caactagttc aaattagtca aaataacata aaatcagctt tttagggctg atttttttcg
    11641 cctaagcaag taaaatatgc tataataaga aagattttag aagaagtctg aaaaggtctt
    11701 ggcaagctca aatcatcatt tgttgcttgt ttttcgtgcc acaggtttct gagtgatata
    11761 tgtaacagga gaagaagcat gtctaaacca attcgtgtgc gttatgcacc aagtccaaca
    11821 gggctcttac atatcgggaa tgcccgcaca gccctattta attaccttta tgcccgtcgt
    11881 cacggaggta cttttatcat tcgtattgaa gatactgacc gtaaacgtca tgttgaagat
    11941 ggtgaacgtt ctcaacttga aaacctaaaa tggttaggaa tggattggga tgaaagccca
    12001 gaaacgcatg aaaattaccg ccagtctgaa cgtctagcac tttatcaaca atatattgat
    12061 aaattgttag ctgaaggaaa agcctataag tcttacgtga ctgaggaaga attggcagca
    12121 gagcgtgaac gccaagaagc agctggcgaa acgcctcgct atatcaatga atttattggt
    12181 atgtcagctg acgaaaaagc taagtacatt tcagagcgtg aagcagcagg tatcgttcca
    12241 acagtccgtc ttgctgttaa tgagtccggt atttacaaat ggactgacat ggttaaaggc
    12301 gatatcgagt ttgaaggtgg caacatcggt ggtgactggg ttattcaaaa gaaagatggc
    12361 tacccaactt ataactttgc cgttgttgtt gatgatcatg atatgcaaat ttctcacgtt
    12421 atccgtggcg atgaccatat tgccaatacg ccaaaacaat tgatggtcta tgaagctctt
    12481 ggctgggaag cgccagagtt tggtcatatg actcttatca tcaattctga aacgggtaaa
    12541 aaattatcaa aacgcgacac caataccctc caattcattg aagattaccg caaaaaaggt
    12601 tatatgcctg aagctgtctt taacttcatc gcccttcttg gctggaatcc tggcggagaa
    12661 gaggaaatct tctctcgtga gcaactgatt gccctttttg atgaaaatcg ccttagcaag
    12721 tcgccagctg cctttgacca gaagaaaatg gattggatga gcaatgagta tcttaaacat
    12781 gcggattttg aaacagttta tgccctctgc aaacctttcc ttgaagaggc aggccgtttg
    12841 acagaaaaag ctgagaagct agtagaatta tacaaacctc aattaaaatc tgcagatgag
    12901 attattccat tgactgacct tttcttttct gatttccctg aattaacaga agccgaaaaa
    12961 gaagtgatgg caggtgaaac agtttcgaca gtcttgcaag ctttcaaggc taagttggaa
    13021 gctatgtcag atgaagactt caaaccagaa aatattttcc cacaaattaa ggctgttcaa
    13081 aaagaaacag gaatcaaagg gaaaaacctc tttatgccta ttcgtattgc agtatctggt
    13141 gaaatgcatg gcccagaatt accaaatacg atttatttat tgggacgtga taaatccatt
    13201 gagcacatca aaaacatgct ataaggctgt atcgttcacc tttattttta aacgctttaa
    13261 ggagttaaaa agtcacgaca acgaaagatt gaagattaag ttcttcagtc ttttttatcg
    13321 ttatctgagc ttgctacctt ggtaaagtaa aaaatagtat agtttatttc tattttggag
    13381 attggatttg aaagagaggt ggtgagatgc ttacgtgata atgacagcaa acggtgaggt
    13441 tttgattagt gtgatttaaa gaaatggttt ttatgaatca attagtgtac aatatttttt
    13501 tggtatatgc tgaaagagac tagtttagta ttcacttagc taatcaattg taatcaaata
    13561 atattgtaat cattgtcata aaatatgcta aaataataaa gttggaaagg agaaaaaatg
    13621 gctaatagcg aatatatgtt tttattatta tcaattattg tctattatat gacaaaaatt
    13681 tatatttttt cctttctatc tgatatcaca ttaccagttt ggaaacaact aacgattttg
    13741 gctttagccc tatttttcaa tcagttcccg tatttgtcgc cattgctaat tgatcctcta
    13801 ttatttttag ttgttttaag gcaagaaacc aagcaattat tttctttgaa agctcttttt
    13861 ttggctgttg cacctagtgt tttggtggat ttgctatctc gatttatggg tacaatcgtt
    13921 atcccctatc tttttttgtc gagtggtatt tatctgggtc atattatctt tgacttgctt
    13981 gcttatctgc tgatttttcc aagttttgct attattaatt atatgattgg aaaagattac
    14041 aaggtgatat gccaatccgg atattcgaaa cgatcgcata atttctatca aacattgctg
    14101 atttttgttt tggtttatta tgtggacatt tttgtcattt taggatttac ggaccccttt
    14161 ttacattttc atcattctct ttttgttccc acaccttata agttattgtt tttgatgttt
    14221 atacttcttt tagtttatct tctatcttat tttaatcata gttctaaaga ataccttaaa
    14281 aatgagttga gaagagaaca acaagcttat atgactaact tagagactta tgggaaacat
    14341 cttgagaaac tctatcgaga tgtaagagct tttcaaagtg attacctgag ccgtatagag
    14401 cgtttaggtc aagccattaa gagtgaatcc attactcaga ttcaagatat ttatgcccaa
    14461 acggttcatg aagctaacga ctactgggat gataaacact ataatatctc gaagcttagg
    14521 aaaattaata tctcatcgat taagagctta ttgtcagcta aaattatcag tgcggaaaaa
    14581 tcaggtattg atttgaatgt ggaagtgcca gataatataa aagagactta cattcctgag
    14641 ttggacttac tattgttgat gtctattttt tgtgataacg ccattgaggc agctcttgaa
    14701 gcacagcaac ctcatatgtc aattgcttac tttttgttag atgactatca gatgtttgtt
    14761 gtgacaaata cgactaaaaa aaaaggtaga cattaacaag atctttgaag aaggctattc
    14821 ttcaaaaggt tcagaacgtg gtatcggcct ttctaatgcg cagcgtattc tcaaaaagta
    14881 tccttattta tccttgcgga ctaaaagttt tgataaggaa tttagccaaa ccttgaccat
    14941 gccaaaggag gaggtggata gatgatggtt atatacagta tggctttatt ctatgctacc
    15001 atctttatta acagctgggt catttttgca aaggtttctg ctattaaact aagctggaaa
    15061 cgggttagcg ttataggcat tagttttgta attgctaata tgatatttga caaagtcatt
    15121 ttgattgacc aactgttttt tattattgtt agtttgttaa gtgctccgaa aaagaaatta
    15181 tttgagcata tgtttaatgg tttctttact atcttgattg tcgaattact gtttcgcgtc
    15241 atcggatctt tctttttacc agctgtctta ggatttagca ttggtcaaat taataataac
    15301 cttaagcttt tagagttatg ttatcttttt gtattaccaa tattttatct gtttagctac
    15361 attttcagta ttgacttaag cttaataagg tttatcagtg aagataagat gaaaaagtgg
    15421 gtattttgga tgaatactgc catgttttct tactactttt tcgcccattt tttggtaact
    15481 gtgcaaagcg gatttcttgc actatatttc cagtaccggt ctattttagt atttatttat
    15541 ttagctattt ttatttgggt tattgtgaaa ttagatcgat ttgctaaaga tcagctgtca
    15601 caaaaattaa cacaagcaca aaatgaacgt attgcgtatc ttgaaaatta caatcaatcg
    15661 attgagcaac tttaccgaga aatcagaaca gttaaacatg attctgaaaa tattttaatt
    15721 agtctaaaag atagtatcga tagtggtgat atagatctga ttactagagt ttatgacacg
    15781 gttattcagc aatcggcaac ttctatgatg cgcacaaatt atgaaatatc ttctttagac
    15841 aatatcaaag agactgtgat tcgcagcatc atgaattcca aattgcttga agctcagtat
    15901 ttgggtattg aactttatat tgagattcca gatgttatcg atcatttacc tattaagtta
    15961 atcgacttaa ttgtactttt tactggacta gtggacaatg ctattgagac agccaaaggc
    16021 agtagacgtc cttttttatc tattgcatac tttaaacaag ataacaagca attatttatt
    16081 attgaaaata gcacaaaaac caatcgtgtg gatatagcca aacgctttga tgctcagcag
    16141 cagaactcag cccacttttt gactgtttta gatagttacc cccaaataac gctttcgact
    16201 aaaagtgacc attatcgatt aagacaattg ttagaaatga gataaagtat gatgaacatt
    16261 tttattcttg aggatgattt tatccagcag acacgcatag aatctatcgt agtaggcatc
    16321 ttaaaagaga ctagaatacc atgtaatcag cttgaagtgt tctcgactcc tcaaaaatta
    16381 tttgagagta tccaagaaag aggagaccat cagctgtatt ttttagatat tgaaattggt
    16441 gaatatactc gttgtgggct tgaattagct gcagctattc gacaaaaaga tcctaatgcc
    16501 gttattgtgt ttgtcaccac tcattcagaa tttgctccta tttcttttaa atataaggta
    16561 tctgctctag attttattga taaagcaggt ggtcaaaaac agtttaaaga acaaatcgaa
    16621 gaatgtatcc gatatactta cgatatgatg tctagtcgtg agtcaaagga catgttttta
    16681 tttgagactc cacagacaag attaaaattg ccttataagg atattttata ctttgctaca
    16741 gccacaactc ctcacaaagt ttgtttatgg actcagacag aaagattaga gttttatggt
    16801 aatctatctg agattcaagc agtagcaccg aaactttttt tgtgccatag atcctacctt
    16861 gtgaatctag ataaggttgt tcgaattgat aagagtaagc agctccttta tttcgaaaat
    16921 ggtgattctt gtatggtatc acggttaaaa atgaaatgtc tgtttgaacg gtgggaggcc
    16981 cttcgctaaa gttaagagtg caataacatt ttaggacgaa aaagcaacat ttcaggaaat
    17041 gatgctctta ttgaagtatt tttcgctata ataattaatg taaataaaga tttacgaagt
    17101 catgagttta tcgagcaatc aatccccaat tcaatcaaaa tattgttttc tctctctcca
    17161 taaacaaata gtatttttga tatgatggct cggcagacaa aatgacgatg tcagttgtct
    17221 ttgtttggat atcacattag ctggttgtaa aatcagtatt aaagcccggc ttgccgggtt
    17281 ttttgatagg taaatacagg gataagtagc tgacgtcttg tggattctga ctttttatgg
    17341 ttgttttctg aaggttattc ctttgtcgaa agaagaacta tactacgaaa agatggagtg
    17401 acaagaggca gttgaagcac aaaaactaga aatagtacag aaagaggctt aatctgaaag
    17461 ggttagggct ttttaatttt ttaggggatg tggtataatg gtaataattt agatattgga
    17521 gttaaatttt gaagaagacc tatcgtgtca agcgtgagaa agatttccaa gccatattta
    17581 aggatggaaa aagtacagca aatcgaaaat ttgtcattta tcatttaaat agaggccaag
    17641 accacttccg tgtgggtatt tctgtcggta aaaaaatagg aaatgcagtc accagaaatg
    17701 cagtcaaacg aaagatacgt catgttatca tggcattagg gcatcagctg aagtcagagg
    17761 atttcgtggt gattgcccgt aagggtgtcg agtctttgga gtatcaagag cttcaacaaa
    17821 atttacatca tgttttaaag ttagcacaat tgcttgagaa aggttttgag agtgaagaaa
    17881 aacattaaaa ttgcaagaat agtcccctta gttctattat tagtggcctg tggtcgtggt
    17941 gaggtaacgg cacaatcatc tagtggttgg gaccagttgg tttacttatt tgccagagca
    18001 attcaatggc tttcctttga tggttcaatt ggtgttggca ttattctttt tacccttact
    18061 atccgtctca tgctcatgcc tttgtttaat atgcaaatca aatcaagcca gaagatgcaa
    18121 gacatccaac ctgagcttag agaattgcaa aagaaatacg ctggtaaaga cacacaaacg
    18181 cggatgaagt tggctgaaga aagtcaagcc ctttacaaaa aatatggggt taacccttat
    18241 gccagtctct tacccctctt aattcagatg ccagttatga ttgccctatt ccaagccttg
    18301 acacgggtat ctttcttaaa aacagggact ttcttgtggg tggaattggc acaacatgat
    18361 catttgtacc ttttaccagt tttggcagct gtcttcactt tcttgtccac ttggttgacc
    18421 aatctagcgg ctaaagaaaa aaatgtcatg atgactgtta tgatttatgt gatgccgcta
    18481 atgatcattt tcatgggctt taacttggct agtggagtag tgctctattg gacggtctcc
    18541 aatgccttcc aagtgttaca actactgtta ttaaacaatc cttttaagat tattgccgaa
    18601 agacagcgtc ttgccaatga agaaaaagaa cgccgtcttc gtgaacgtcg tgctcgtaaa
    18661 aaagcaatga agagaaaata ggagtttagg ttatggtatt atttacagga aaaacagtcg
    18721 aagaagctat cgaaacagga cttcaagagt tagggttatc acgccttaaa gcgcatatca
    18781 aagtcatttc aaaagagaaa aaaggtttcc tcgggtttgg taaaaagcca gcccaagttg
    18841 atatcgaagg tatcagcgac aagacggttt ataaggctga taaaaaagcc actcgaggtg
    18901 ttccagagga tattaatcaa aaaaatgctc ccgtggtcaa ttctgctgat gtagaacctg
    18961 aagaaataaa agccactcaa aggttagaag cagaagatac caaagtggtt cctctcatgt
    19021 ctgaagatag tccagcgcaa accccttcta atcttgctga gacagtcact gaaagaaaag
    19081 cacaacaacc gtcaatccca gtcgaggaat cagaagtgcc ccaagatcct ggtaatgatg
    19141 gtttcagcaa agatattgaa aaagctgctc aggaagtgtc cgattatgtg actaaaatca
    19201 tctatgaaat ggatatcgaa gccaccgttg aaaccagcaa caatcgtcgc caaatcaatt
    19261 tgcagattga aacgccagag gcgggacgtg tgattggtta ccatggtaag gtcttgaaat
    19321 ccttgcagtt gttagctcaa aatttcttgc acgaccgcta ttcaaaaaat ttttcagtat
    19381 ccttgaatgt ccatgattat gtggaacatc gaacagaaac cttgattgac tttacgcaaa
    19441 aagttgccaa acgcgtcttg gaatctggcc aagattacac catggatccc atgagtaaca
    19501 gtgagcgtaa aatcgttcat aaaaccgttt catccattga aggggttgat agttattctg
    19561 aaggcaatga ccctaaccgc tatgtggtag tcagtcttca acgttagatc ctaaaaagaa
    19621 tcgttggtag ttagtttagc tatcgaagat tttttgtatg gccagcttaa ccgtttgttt
    19681 tactgatctc attgattatt gttgctattg ataaggtttc aacggtaagg caaaggaaca
    19741 gtgtcaaaga agagacactt tatgaaatga gcggcctctt aaatgagaga gaaactgttg
    19801 aaaaacgaaa ataaatcttg acagtagacc ctctttaaga tagaatatta tagtatgttt
    19861 agtaactgat atcacaaata gccggctaaa cgaatacaaa atctatgagg aggtattcac
    19921 tgtgaaacgt acttatcaac caagtaaaat ccgtcgtcaa cgtaaacacg gattccgtca
    19981 ccgtatgtca actaaaaacg gacgtcgtgt gcttgctgca cgtcgtcgta aaggacgtaa
    20041 agtattatca gcttaattgc aaaaaataca actaaagtaa accaagagtg ctcgaggctc
    20101 ttggtttttt aacgttttct aatcggaaat ttgcaatgta taagtatggt gtcaactcct
    20161 tacctcctta tttgttgtat gaaagagcat tccaaataat agaaaataat ataaaaaatg
    20221 aaagtagatt ctaaaagtct catcgctatt gaaagcgctt tattttttgt tataataact
    20281 ttgtgaacgt tatttttatt aaaactaaga aacacaagga gtagaaacta tgcctgataa
    20341 accaaccaaa gaaaagctca tggagcagtt aaagggtgag attatcgttt cttgtcaggc
    20401 tttgccaggt gagcctcttt attcagagac tgggggtatt atgccactgc tggcaaaagc
    20461 tgctcaagaa gctggtgctg tcggcatcag agctaattcg gttagggata ttaaagaaat
    20521 tcaagccata acagacctac caattatcgg tatcatcaaa aaagattacc cgccgcaaga
    20581 gccttttatc acggcaacga tgaccgaagt ggaccaatta gctgccttaa atattgcagt
    20641 gattgctatg gattgtacca agcgtgaccg acatgatggc ttggatattg ctagctttat
    20701 tcgacaagtt aaggaaaagt accccaatca gcttttgatg gcagatatta gtacctttga
    20761 tgaaggacta gtggcccatc aggctggcat tgattttgtt ggaacgaccc tctcaggcta
    20821 caccccatat agccgtcaag aagcaggtcc tgatgtggca ttgatagaag ctctttgcaa
    20881 agcaggcatt gctgtcattg ccgaaggaaa gattcattcc ccagaagaag ccaagaaaat
    20941 taatgactta ggtgtggcag gtattgttat tggaggggcc attacaaggc ctaaggaaat
    21001 tgcagagcgt tttatcgaag cgctcaaatc ctaatagtgg ttgtcaaaat agaaacacac
    21061 atcaaaaaaa ggagatttta cgatgaatat gaagaagttt gcttcattag cgatgcttgg
    21121 tgcatctgtt ttaggattag cagcctgtgg cggaaagagc cagaaagagg ccagtgaaag
    21181 taaatctgat gctgctaaaa cagaaatcac atggtgggct ttcccagtct ttacgcaaga
    21241 aaaagctgaa gatggtgtgg gaacttacga aaagaaattg attgctgcct ttgagaaagc
    21301 taatccagaa atcaaggtaa aattggaaac cattgatttt acatctggtc ctgagaaaat
    21361 cacaactgct attgaagctg gaacagctcc tgatgtcctc tttgatgctc caggtcgtat
    21421 cattcaatat ggtaaaaatg ggaaattggc tgacttgaat gacttgttca caaaagagtt
    21481 taccaaagat gttaacaatg acaaattgat tcaagcctca aaagcaggag atacagctta
    21541 catgtatcct attagctctg caccattcta catggcgttg aataaaaaaa tgctcaaaga
    21601 tgctggcgtc cttgacctgg tgaaagaagg ttggacaact gacgattttg aaaaagtctt
    21661 gaaagcattg aaggacaaag gatataaccc aggttctttc tttgctaatg gtcaaggtgg
    21721 tgaccaagga ccacgtgcct tctttgctaa cctttatagt agtcatatta ccgatgacaa
    21781 agtaaccaaa tacaccacag atgatgctaa ctctattaaa gccatgacca agatttccaa
    21841 ttggattaaa gatggtttaa tgatgaatgg ctctcaatac gacggttcag ctgatattca
    21901 aaactttgcg aatggccaaa cttcctttac cattctttgg gcgcctgcac aaccaggcat
    21961 ccaagctaaa ttgttagaag ctagtaaagt ggattacctt gaaatcccat tcccatcaga
    22021 tgatggcaaa ccagaactag aatacctcgt aaatggtttt gcggtcttta ataacaaaga
    22081 tgaacaaaaa gttgctgcct ctaagaaatt tatccaattt atcgctgatg ataaagaatg
    22141 gggacctaaa aatgttgtcc gtacaggtgc ctttcctgtg agaacttctt acggggatct
    22201 ttacaaagac aaacgaatga aaaaaattgc tgaatggaca aaattctact caccatacta
    22261 caacacgatt gatgggtttg ctgaaatgag aactctttgg ttcccaatgg ttcaagccgt
    22321 ctctaatggt gatgaaaagc cagaagatgc tttgaaagcc ttcactgaaa aagcgaacaa
    22381 gacaatcaaa aaaacacaat aagtgttcag aacaagtggc ttcttttcac ggcacatgtc
    22441 aaatggtcac tggaaaggag cctttccttt ttttaggaga gattaataga aaaagaggta
    22501 ttacaagtga acgtcaataa attaaaaatg agagagacgc tcatctcata cgctttttta
    22561 gctccggtct tggttttctt tgtgattttt gtcttgatac cgatgattat gggctttgtg
    22621 acgagttttt tcaattattc catgacggat tttacctttg ttggttttgc taattatgct
    22681 aggatgtttc aagatcccat tttcatgaag tctcttatta acaccttgat tattgttatt
    22741 ggttcggtac ctgttgtagt tttcttttcc ctctttgtgg ctgctaagac ttatgacaaa
    22801 aatgtggtgg cacgttcgtt ttatcgggca gttttctttc tacctgttgt taccggaagt
    22861 gttgccgtaa cggtggtttg gaaatggatt tatgatccga tgtcagggat tttgaattat
    22921 gtcttaaaat atgctcatgt gattgaacaa aatattagtt ggctgggaga taagcactgg
    22981 gctttgttgg ctattattgt tattttatta accacatctg ttgggcagcc tattattcta
    23041 tatattgcag ctatgggaaa tattgataac tctttggtag aagctgcgcg tgtggatggg
    23101 gcgacggaat ttcaggtgtt ttggaatatc aagtggccaa gtctgctgcc aacaacctta
    23161 tatattgctg tcataacaac aattaattcc ttccaatgtt ttgctttgat tcaactcttg
    23221 acgtctggag ggccaaatta ttcaaccagc accctcatgt actatttgta tgaaaaagcc
    23281 tttaagctct ctgaatacgg ctatgccaac acaatgggtg tattcttggc agtcatgatt
    23341 gcaatcatca gctttgctca atttaaaatt ttaggtaatg atgtggaata ttaggaggat
    23401 attaagatga agaaaaagaa actaaccgca tcggatgttc tgactactgt tattctatgc
    23461 atcttgacca ttttgtttat tttcccattt tattggatta tgacaggagc attcaaggct
    23521 caagccgata ccattatgat tccaccgcaa tggtggccaa aggcacctac tattgaaaat
    23581 tttaaggcct tggtagtgca aaatccagcc ttaaaatggt tgtggaatag tgtctttatt
    23641 tcggtggcga ccatgttctt ggtttgtggc acttcctctt tggctggcta tgctttggcc
    23701 aaaaagcggt tttatggaca gcggcttttg ttttcgattt ttattgctgc tatggccttg
    23761 ccaaaacagg ttgttctagt gcctcttgtg cggattgtta attttatggg aatccatgac
    23821 actttggcgg ctgttatttt gcctcttgtg ggctggccat ttggtgtttt ccttatgaaa
    23881 cagttctcag aaaatattcc aaccgagtta ttggaatccg ccaagattga tggatgtggc
    23941 gagattcgca cctttttcaa tgtggctttc cctattgtca aaccaggctt tgcagcgcta
    24001 gcgatcttta cctttatcaa tacttggaat gattatttta tgcagttggt gatgttaacc
    24061 tctcgggaaa atttaacgat ttcacttggt gttgctacta tgcaagctga aatggctact
    24121 aattatggct tgattatggc aggtgctgcc atggctgcag tgcctattgt aacggtcttt
    24181 cttgtcttcc aaaaatcatt tacccaaggc attactatgg gtgctgtgaa aggttaaatc
    24241 aagaaaggtt tctaacatga tttatgatcg tttaaaaaat attagccgtt accgagggat
    24301 tcaccctcat ttggatgcgg cgattacctt tttacaaacc acagatttga ggcaactagc
    24361 tgaagggaaa tatcctattt taggggagaa agtatttgca gttattcaaa gaaatcaatt
    24421 gagtaaagcg gacaattcat tgttggaata ccacaaacgg tatgcagatt gccacctttt
    24481 gctagctggg aatgagtgca ttcgttatgg tataggtaat caagctgaag tagtgccttt
    24541 tgaacaagaa gctgatattg gctttgtaac ctgtgatcga acctatgacc tagatttggt
    24601 tgatgatagc tttgcttact tttttcctaa tgagcctcat caacccaata attttaacca
    24661 agcaggggaa gcagttacaa aatgcttaat caaagtgtta atggcagatt aggttgattt
    24721 ggcagtgaac caattgatgg aaaggaagtt gtgatttgac gtcgaaaaaa cagggacttt
    24781 tacattctct ttttaatctt gatagtaaat ggatgagggc tagtgcagca ctgtttgatt
    24841 tgcttgtgtt taatctctta tttgtcttgt cctgccttcc ccttctaacg attggggttg
    24901 ctaaaatggc tttgtatgcg agtttgttgg attggcgaga aggtcaagtt agtcagcttg
    24961 ttactactta tagctctcat tttaaacatt attttaaaag tgggatgcgc ctaggtctta
    25021 ttgagctttt gataatgagt atttgtgtct tagatctttt cttaattcga aaccaatcag
    25081 gcctagtttt tcaagggttt aaagtacttt gcattgctgt tttatttctg gtagttatac
    25141 tctttttgta cgcttatcct caggccgtca gaaaagagct ttccctatct acgctgttta
    25201 agcgaacctt tttactagcc ggactctttt ttccatggag ttttgctttc ttggctctta
    25261 tttgtctcac gatatttagc ctacaattgt ctctgttaac gttatttgga ggcgtgtctt
    25321 tgctagctat catcggcatc agtagcctaa cttacctcta cttgattatc atggaatccc
    25381 ttcttaggcg attcccactt aataatgaca ttgaataaag gacattacta tgacagatct
    25441 tacgaaatac caaggcatta ttcctgcctt ttatgcttgt tacgatgacc aaggagctat
    25501 tagccctgag cgtgtgcgtg ccttgaccca gtactatatt gacaaagggg ttcaggggct
    25561 ttacattaat ggctcttctg gagagtgtat ttaccagagc gtttttgacc gtcaattggt
    25621 gttagaaaat gtcatggcag tcgctaaggg caagctgacg attattaatc acgttgcctg
    25681 caacaacact aaagatagta ttgaattggc agctcattca gaacgtttgg gcgtggatgc
    25741 cattgcagct attccgccta tttatttccg gttaccagaa tatgcggttg ctgattattg
    25801 gaatgcgatt tcttcggctg ctcctcacac agattttatc atctataata ttcctcaact
    25861 ggcaggggtt gccttgaccc caagccttta taagactatg ttggctaata agcgcgtgat
    25921 tggcgttaaa aattcatcca tgccagtgca ggatattcaa accttctgtg cgattggcgg
    25981 ggacgatcat attgttttta atggcccaga tgaacaattt ctaggagggc gcttgatggg
    26041 ggctgctgct ggtattggtg gtacctacgg ggctatgcca gaattatttt taaggctgaa
    26101 tcaacttata gttgacaagg atttagaaaa ggccaagacc tttcaatata ctattaatga
    26161 gattatcggt gtccttgttt ctgctcacgg caatatgtat ggggttatta aggaagtact
    26221 tcgtattaat gagggtcttg atattggttc tgttcgatca cctttagctg agttggtcga
    26281 ggaagatagg gttatttgcc aacgggctgc tgctctgatt aatcaggcta aggaaacctt
    26341 ttaataagat gcgaggggat aacaaatgaa gcattattta gcaattgata ttggtggtac
    26401 tgctatcaag tatggcttga tttctgaaac aggagacctg ttggaaaaag aggaaatggc
    26461 cactgaggct tataaaggtg gtccctctat tttggaaaag gtcaagggct tggtaaagac
    26521 ctatcaagac caaatggatc tggctggagt ggccatttct tctgcaggaa tggttaatcc
    26581 tgataaggga gaaatctttt atgccggccc tcagattcct aactatgctg gaactcagtt
    26641 taaaaacgag attgaagaga ctttcgggtt accgtgtgaa gtggaaaacg atgttaactg
    26701 tgctggtcta gccgaagcta tttctggcag tgccaaggat tatcctgtgg ctctttgctt
    26761 gacaattggg acgggaatcg gtggctgttt attgtttaat tcccaagttt ttcatggtag
    26821 tagtcattca gcttgcgaag ttggttacct tcatttgtca gatggtcagt ttcaggatct
    26881 ggcatctacc acagctcttg ttcaagaggt ggccttagct tatggggatg acattagcca
    26941 atgggatggt cgtcgtattt ttgagcaggc taaagcgggt gatgcgattt gtatagcagc
    27001 cattagtaag caggtggatt acttaggaca aggtattgct aatatctgct acgttgttaa
    27061 cccaaatgtg gtggtacttg gtggcggtat catggcgcaa aaagattatt tagctgataa
    27121 attaaagaca gctcttgata gctacttggt ttctagtctt gccaagaaaa ctcagctgaa
    27181 gtttgctagt catggaaata atgctggtat attaggagct tactaccatt ttaaacaaaa
    27241 gaatgagcga tcctgttcat ttataactcc tgagaaaatc gaaaataatt tagcgagtag
    27301 ctaatcttag tggctgtgag tctatatgac gtgaagagtt cttgtttaag tatactgggg
    27361 gaggtgaatg acgacccttt aaaaagaaaa caacgccctt tttgctattg tagtctaaag
    27421 gtcgttattt tctttgtcaa taatagtgtt tttgaagatt ttttctttgt gcggtttgtc
    27481 aatcgctaaa acgtaagcat aaataatgtc catcataata agaagaggaa attgtggtga
    27541 cacacgattc ccataatgta gttggtgggt tgatgatacg ggaataatat ctaaggagtc
    27601 gtcaaattcg gtttgattat ctgttgttaa gaggacagtt ttggcccctc gctgactagc
    27661 ttgatgaagt gctgtgatga cagagtttgt tttgccagat aaagaaaaac caaaaacaag
    27721 gcaattatca ttgacgaggc tatttgccca agtaaaacca tcagtgtctg aataagcatc
    27781 acagattaaa ccaagtcgca taaagcgtag cttcatttct cttgctacta gtccagaaga
    27841 tcctttgcca aagaaataga ctcgctcaga agcatcgatc agcttggcta agttcagtaa
    27901 tttttcctca ttaacgagct cataggtttt attaataaga gcatcgtagt ccatcagcac
    27961 gcgctttgtc aattctaagt gaatagattg gaaagtctct tgtgattctt gaagactgtg
    28021 aaggtaatca aaggcaaaag cacgataacc agtaaaacca cacttttttg caaatcgagt
    28081 caaggcggct tgagagatgt gtagtcgctt aactatctcg gatgcggtca actcttgagg
    28141 tgtcagatcg gttgtaataa aaaaatgagc aatccctttt tctaaactag tcatatgttc
    28201 caatgatgct tcgattttag taattaggcg gtggttttta ggcatagcaa agcacactcc
    28261 ttacagttta actatctact agtatagcat agatcgctaa cagaaggtag cgaccctttt
    28321 tgtgatacag atttgttcaa cccactttat ttgagtaggt tgtagtattt ttgagggctt
    28381 atgtaggagc cgactattaa aggtcatttg tcaaaaaagt agaaaataga caagtgtcag
    28441 ctagcaaagg gttttacgat caacctaaac ggcagaagtt ctcaccaagt tttctgatgt
    28501 ggttaagatc tttatgttat aataacatca tgacaaataa agtagaaaaa ctaactattt
    28561 ttgataccca tacgcacctg aatgtagcag aatttcaagg acacgaaact gaagaattga
    28621 ctttggctca agaaatgggc gtggcctacc ataatgtggt tggctttgac caggccacta
    28681 ttagtggagc acttgctctc gcagaccagt atcctaacgt gtatgctact attggatggc
    28741 acccgacaga agcaggatct tattctgaag cagttgagga gtctatcgtc tctcaattat
    28801 cacatcctaa agtcattgcc ttaggtgaaa ttggcttaga ctattattgg atggaggacc
    28861 ccaaagaggt gcaaatagag gtttttaagc gccaaatgca attagcaaaa gaccatgatt
    28921 tgccttttgt ggtgcacacc cgcgatgcct tggaagatac ctatgagatc atcaaagcag
    28981 ctggtgttgg ccctcgtgga ggcatcatgc attcttactc agggtcatta gagatggctc
    29041 ggcgttttgt ggatctgggt atgatgattt ctttttcagg tgtggtgact ttcaaaaagg
    29101 cccttgatat tcaagaggca gcgcagcact tgcctttgga taagattgtg gtggaaacag
    29161 atgcccctta tcttacacca gttccaaaac gtggcaaaca aaatcataca gcttataccc
    29221 gctatgtggt tgataaaatc gcagagctgc gtggaatgac cgtggaagaa gttgcaaaag
    29281 caacgactgc taatgcaaag agggtattca agcttgactg aaaaaattaa tattcaagag
    29341 gttcttgttg tagaaggcaa ggacgacacg gctaacctac gccgttttta cgaggtggat
    29401 acctatgaga ccagaggctc tgctatcact gaagaagatt tagaacggat taaccgccta
    29461 aatgacttgc gtggtgtcat tgttttgaca gacccagatt ataatggtga gcgcattcgt
    29521 aagctcatta tggcagctgt gccaacagct cgtcacgcct ttttaaaccg aaatgaggct
    29581 actccaagtt ctaagagtaa gggccgttcc ttaggggttg aacatgccaa ttttgaggac
    29641 ctccaaaagg cacttgctca tgtcactcag caatatgatg atgagtctta ttttgacatt
    29701 cgtcaaacag acctgattcg tctagggctt ttaatggcgt cagatagccg taaacgcagg
    29761 gaatacttgg gcgaaaagct ccgcatcggc tatgccaatg gcaaacaact gctcaagcgc
    29821 ctcgaattat ttggcattac cctagcagaa gtggaagaag tgatggaggc atatgaggag
    29881 taaagagtac aataaaatat aacagcccca ttaactgaat ggcgtgtctt ggcaaaaaag
    29941 tttaggctag tggttcaaat gccaaaaaga aagtgatcat aaaaagaaga gaataaaaga
    30001 agagaatata tgagaattgc agattatagc gtgaccaaga ctgtccttga tcgtcacgga
    30061 tttaccttta agaaatcttt tggtcagaac tttttgaccg ataccaatat tttacagaaa
    30121 atcgttgaca cggctgagat tgatcagaat gtcaatgtta tcgagattgg tcctggaatt
    30181 ggggctttga cggaattttt ggcagaaaat gctgctgaag tgatggcttt tgagattgat
    30241 gaccgcttgg tgccgatttt ggcagatacc ttgcgtgatt ttgataatgt gcaagtggtc
    30301 aatcaagata ttttaaaagc tgatttgcag acccaaatca agcagtttaa aaatcctgat
    30361 ttgcccatta aggtggtggc taacctgcct tactacatca caacgcctat tctcatgcac
    30421 ttgattgaga gcaagattcc attccaagag tttgtggtca tgatgcagcg tgaagtggca
    30481 gatcgtatct cggctgagcc aaacactaaa gcttatggtt ccttgtccat tgcggtgcag
    30541 tattacatga ctgccaaggt tgccttcatt gtgccgcgca ccgtctttgt acctgcacca
    30601 aatgtcgata gtgctatcct taaaatggtg cgtcgcgacc agcctttgat tgaggttgag
    30661 gacgaagatt tctttttcag agtgtctcgt ctcagttttg tccatcgtcg caagaccctg
    30721 tggaataact tgactagcca ttttggcaag tctgaagata tcaaggctaa acttgaaaaa
    30781 ggtctggcac tagcagatat caagccttct attcgtggtg aggccttgtc gattcaagat
    30841 tttggcaaat tagctgatgc tttaaaagaa gttggattat aaaagctttc ccccggtgac
    30901 aataaaaaat tcccttgtag acaaaacaga gatgttcagt tcagggggat ttttcttatt
    30961 gaagctgacc gttaaggcat cgcagtgcag agctagtttt tttaataccc cggaaaaaaa
    31021 ggggcaatta acaagagcgt gactatagcg gtacggttag actctttttc gtaaatagca
    31081 aaggtctttt taaaattcac atcgtttcct acctcaaaaa atcatcagtg atctgatttt
    31141 tagttgataa aatattctat ttttaaaaag cagtgaccta aatgatagcc agtggtctag
    31201 agaatcttga cagtttttaa agcgagtgaa acttagactc aaatgctgat ttgggagcgg
    31261 ttttctgata taatagagtt attatagtag ggcaaaggag cacagttgca aggtaaaatc
    31321 attaaatctc tggctggttt ttattacgtg gagtcagaag gacaggtata tcagacgcga
    31381 gcgcgtggta attttaggaa gcgcggtgag acaccttatg ttggagatat cgtggatttc
    31441 tcagcagagg acaactctga aggttatatt ttagcgattc atcctcgtaa aaacagtttg
    31501 gtaagacctc ctatcgtcaa tattgaccaa gcagtggtta ttatgtctgc taaagaacca
    31561 gaatttaaca gcaatcttct agaccgcttt ctcatcttgc ttgaacacaa agccattcat
    31621 ccagtggttt atatctctaa gatggactta ttagatagtc ctgaggagat taaggctatt
    31681 ggtcgacagt atcaggcaat cggttacaat tttgtgacca gtcttgagga attgttgcct
    31741 ttgctagctg ataaaattac cgtctttatg ggacaaacag gtgttggaaa atcaaccctt
    31801 ctcaaccgaa tcgcccccga attggctctt gaaacaggag aaatctcaga tagtctaggg
    31861 cgtggtcgtc acaccacccg agctgtgagt ttttacaata cccatggcgg aaaaatcgcg
    31921 gatacgccag gtttctcatc attagactat gatattgcta atgctgaaga tttgaacgag
    31981 gcttttccag agctgcgccg gctgagccat gagtgtaagt ttagatcctg tacccatacc
    32041 cacgaaccca agtgtgctgt caaggcagcg cttgaaatgg gagagttgtg gccagttcgt
    32101 tatgagcatt acctgcaatt tctcagtgaa attgaaaacc gtcgtgaaac atataaaaaa
    32161 gttatcaaaa gaaagtaggt ctactccatg tcaactctaa aaattgcccc atctattcta
    32221 gcagctgatt acgctaattt tgcttctgag ctagctcgta ttgaagaaac agatgccgaa
    32281 tatgttcaca ttgacattat ggatggtcaa tttgttccta acatcagttt tggtgcagat
    32341 gttgtggcaa gtatgagaaa gcacagtaaa ttggtttttg attgtcattt aatggtggtt
    32401 gatcctgaac gctatgttga ggcttttgct caagctggtg ctgatatcat gaccattcac
    32461 acagaaagta ctcgtcatat tcatggagcc cttcaaaaaa tcaaggcagc tggcatgaaa
    32521 gcaggggtag tgattaatcc aggaactcct gcaacagccc tagaaccttt gctagactta
    32581 gttgaccaag tcctcattat gacagtcaac ccaggttttg ggggtcaggc ctttatccca
    32641 gaatgtttag aaaaagtggc taccgtagcc aaatggcgag atgaaaaagg attgtccttt
    32701 gacattgagg ttgatggcgg agtagacaat aagaccattc gtgcttgtta tgaagcaggg
    32761 gccaatgtct ttgtggcagg ttcttacctt ttcaaggcca gtgacctagt gagccaagtc
    32821 caaaccttaa ggacagcctt gaatgtctaa agttgctctt tttgcgggag gagatctctc
    32881 ttatatcagc cgtgattttg attattttgt cggtattgat agagggagcc tatttttatt
    32941 agaaaatggg cttcctttga atatggctgt tggtgatttt gattcggttt cccaaaaagc
    33001 atttacggat ataaaagaga aggcagagct tctcatcact gctaatccag aaaaaaatga
    33061 tacggatacg gaattagccc ttaaagaggt ctttgctcgt tttcctgagg cggaagtgac
    33121 catttttggg gcttttgggg gtcgaatgga ccacctctta tccaatattt ttttgcctag
    33181 cgaccctggt attgctccct ttatggcaca aatcgccttg cgtgaccaac aaaatatgat
    33241 tacctaccgc ccggcaggtc agcaccttat ccatcaagaa gaagggatga cctatgtggc
    33301 atttatggca gaaggagaag ctgacttgac cattactggt gctaaatttg agttgacgca
    33361 agataatttt ttcaaaaaga aaatctattc cagtaatgcc tttatccatc aacctattac
    33421 agttagtttg ccaagtggct acttgattat tattcaaagt aaagattgga gttagtatgg
    33481 accttatctt gttccttttg gtcttggttc tcttaggttt aggggcttat ctgttgttca
    33541 aagttaatgg ccttcaacat cagcttgccc aaaccctaga aggcaacgcg gataatttgt
    33601 ctgatcaaat gacctaccag ttggatacag ctaacaagca acaattgtta gagctaacac
    33661 agctgatgaa ccgacaacaa gcagaccttt accaacaatt aacagatatt cgtgacgtct
    33721 tgcaccgtag tttgtctgat agtagggacc ggtctgacaa acgcttagaa aaaattaacc
    33781 agcaggtcaa ccaatcgctc aaaaatatgc aagaatctaa cgaaaaacgt ttggaggaaa
    33841 tgcgccagat cgttgaagaa aaattagaag aaaccttaaa aaatcgtctg cacgcctctt
    33901 tcgattctgt atccaagcaa ctagaaagtg tcaataaagg cttgggagaa atgcgtagcg
    33961 tggctcaaga tgtgggtact ttaaataagg ttttgtccaa taccaaaaca cgaggcattt
    34021 taggcgaact tcaactaggc caaatcatcg aggatatcat gacatcaagc cagtacgaaa
    34081 gagaatttgt aacggttagt ggttctagtg aacgcgtaga atatgcgatt aagctcccag
    34141 gaaatggtca aggcggttat atttacctac cgattgactc aaaattccct cttgaagatt
    34201 attaccgatt agaagatgct tacgaagttg gtgataaact ggccatcgag gctagccgaa
    34261 aagcacttct ggcagctatc aaacgctttg ccaaagacat tcataaaaag tacttgaacc
    34321 ccccagagac gaccaatttc ggagttatgt tcttaccaac agaaggtctt tattcagaag
    34381 tggtcagaaa tgcggctttc tttgatagcc ttcgtcggga agaaaatatt gtggttgcag
    34441 gtccttcgac cctgtctgct ttgctcaatt ccttatctgt tggtttcaag acccttaata
    34501 tccaaaaaaa tgctgatgac atcagtaaaa ttttgggcaa tgtcaagtta gaattcgata
    34561 aatttggtgg cctgcttgcc aaggctcaaa agcaaatgaa tacagctaat aatacgctgg
    34621 atcagctcat ttcaacaagg acaaatgcca ttgttcgagc cttgaatacc gttgaaactt
    34681 atcaagacca agcaacaaaa tctctcttga acatgccctt attagaagag gaaaataatg
    34741 aaaattaatc aaatgaaaaa agaccagctt tttgaagggt tctacctcat taagtcggca
    34801 gaggttcgta agacaagggc tggtaaagat tttattagcc ttacctttca ggatgacact
    34861 ggcgagattt caggaaatct gtgggatgcc caaccttata acgttgaaga atttaccgct
    34921 ggtaaagtcg tgtttatgaa agggcgacgc gaggtctata atggtacccc tcaggttaat
    34981 caaatcacct tgcgaaatgt tcgcccaggg gagcccaatg atccaaagga cttcaaagaa
    35041 aaggcacctg tcagtgttga agaagtacgt gactatttag aacagatgct ctttaaaatt
    35101 gaaaatgcaa cgtggcaacg aattgtaagg gctctttatc gtaagtatga taaagaattt
    35161 tatacttatc ctgcagctaa aacaaaccac catgcttttg agtcaggcct cgcctaccat
    35221 actgctacga tggtcagact agcagatagc attggagata tctaccctga cttaaataag
    35281 agtctactgt ttgcaggtat tatgttacat gacttagcta aagtcataga attaacagga
    35341 ccagataata cagaatacac cgttcgtggt aacttgattg ggcatatttc cctcattaac
    35401 gaagaaatta caaaagtaat ttcagaacta caaatcgatg ataccaaaga agaagtcatt
    35461 gtccttaggc acgtgatttt aagccatcac gggcaattag aatacggtag tccggtacgt
    35521 ccacgcatca tggaagctga aattattcat atgattgaca atattgatgc taatatgatg
    35581 atgatgacaa cagctcttag ccgtgttagc gagggcgaga tgaccaatcg gatttttgcc
    35641 atggataatc ggtcttttta caagccaaac tattgatcag tgtttctcaa gtaatagttc
    35701 ctttgttttt gtgatgattt ttgatgtgct taacacttat gatggtttca taagtgtttt
    35761 tggctcttgt tatggttatt aagtagaatg tcctttcagt aggaatgttg attagtttat
    35821 cttagattga attcttgcat gatattaata agaacaaaaa aaccaatatt ttcctaatcg
    35881 aatgttcgtt ttttattaac tttatggtat aatagcaaaa agtacataaa aatggggaaa
    35941 ctatgaaatt aagacgaagt gaacgtatgg ttgtcatttc aaattatttg attaacaatc
    36001 cgtataaatt aactagttta aacacctttg caactaaata tgaggccgca aaatcttcta
    36061 tctcagaaga tatcgctatt atcaagaaag cttttgaaga agctaacatt ggtgatatcg
    36121 atacacttac aggagcaagt ggaggcgtaa tttttacccc cagtatttca gaaacagaag
    36181 cgcgtaccat cgttgaagac ctgtgtcaaa ggttatcaga gagtgatcgc atcttacctg
    36241 gaggctatat ctatttgtca gacttgctga gtacacctaa aattttacaa aatattggtc
    36301 gtattattgc caatgccttt aaaggagaaa agattgacgc tgtgatgaca gttgcaacca
    36361 aaggagttcc tttagcaaat gcagtggcta atattttaag tgttcctttt gtcattgtta
    36421 gacgtgattt aaaaataaca gaaggatcga cagtgtctgt caattatgcg agtgcttcta
    36481 gtgatcgtat tgaaaagatg tttctgtcaa agcgtagttt gaaacccaat agtcgtgtat
    36541 tgattgtaga tgatttcttg aagggcgggg ggacgattac aggaatgatc agtctcttga
    36601 cagaatttga cagcacttta gttggtgttg ctgtgtttgc agaaaacgct caatcagagc
    36661 gtgagcaaat gaccttcaaa tcattgctga aagtttcaga gattgatgtc aaaaacaaca
    36721 atgttgttgt agaagttggt aatattttcg ataaatggaa aaaggagaga gaatggactt
    36781 agaacaaacg aagccaaacc aagttaagca gaaaattgct ttaacctcaa caattgcttt
    36841 attgagtgcc agtgtaggcg tatctcatca agtcaaagca gatgatagag cctcagaaga
    36901 aacgaaggcg agtaatactc acgacgatag tttaccaaaa ccagaaacaa ttcaagaagc
    36961 aaaggcaact attgaagcag ttgaaaaaac tctcagtcaa caaaaaacaa aactgacaga
    37021 gcttgctacc gctctgacaa aaactactgc tgaaatcaac cacttaaaag agcagcaaga
    37081 taatgaacaa aaagctttaa cctctgcaca agaaatttac actaatactc ttgcaagtag
    37141 tgaggagacg ctattagccc aaggagccga acatcaaaga gagttaacag ctactgaaac
    37201 agagcttcat aatgctcaag cagatcaaca ttcaaaagag actgcattgt cagaacaaaa
    37261 agctagcatt tcagcagaaa ctactcgagc tcaagattta gtggaacaag tcaaaacgtc
    37321 tgaacaaaat attgctaagc tcaatgctat gattagcaat cctgatgcta tcactaaagc
    37381 agctcaaacg gctaatgata atacaaaagc attaagctca gaattggaga aggctaaagc
    37441 tgacttagaa aatcaaaaag ctaaagttaa aaagcaattg actgaagagt tggcagctca
    37501 gaaagctgct ctagcagaaa aagaggcaga acttagtcgt cttaaatcct cagctccgtc
    37561 tactcaagat agcattgtgg gtaataatac catgaaagca ccgcaaggct atcctcttga
    37621 agaacttaaa aaattagaag ctagtggtta tattggatca gctagttaca ataattatta
    37681 caaagagcat gcagatcaaa ttattgccaa agctagtcca ggtaatcaat taaatcaata
    37741 ccaagatatt ccagcagatc gtaatcgctt tgttgatccc gataatttga caccagaagt
    37801 gcaaaatgag ctagcgcagt ttgcagctca catgattaat agtgtaagga gacaattagg
    37861 tctaccacca gttactgtca cagcaggatc acaagaattt gcaagattac ttagtaccag
    37921 ctataagaaa actcatggta atacaagacc atcatttgtc tacggacagc caggggtatc
    37981 agggcattat ggtgttgggc ctcatgataa aactattatt gaagactctg ccggagcgtc
    38041 agggctcatt cgaaatgatg ataacatgta cgagaatatc ggtgctttta acgatgtgca
    38101 tactgtgaat ggtattaaac gtggtattta tgacagtatc aagtatatgc tctttacaga
    38161 tcatttacac ggaaatacat acggccatgc tattaacttt ttacgtgtag ataaacgtaa
    38221 ccctaatgcg cctgtttacc ttggattttc aaccagcaat gtaggatctt tgaatgaaca
    38281 ctttgtaatg tttccagagt ctaacattgc taaccatcaa cgctttaata agacccctat
    38341 aaaagccgtt ggaagtacaa aagattatgc ccaaagagta ggcactgtat ctgatactat
    38401 tgcagcgatc aaaggaaaag taagctcatt agaaaatcgt ttgtcggcta ttcatcaaga
    38461 agctgatatt atggcagccc aagctaaagt aagtcaactt caaggtaaat tagcaagcac
    38521 acttaagcag tcagacagct taaacctcca agtgagacaa ttaaatgata ctaaaggttc
    38581 tttgagaaca gaattactag cagctaaagc aaaacaagca caactcgaag ctactcgtga
    38641 tcaatcattg gctaagctag catcgttgaa agccgcactg caccagacag aagccttagc
    38701 agagcaagcc gcagccagag tgacagcact ggtggctaaa aaagctcatt tgcaatatct
    38761 aagggacttt aaattgaatc ctaaccgcct tcaagtgata cgtgagcgca ttgataatac
    38821 taagcaagat ttggctaaaa ctacctcatc tttgttaaat gcacaagaag ctttagcagc
    38881 cttacaagct aaacaaagca gtctagaagc tactattgct accacagaac accagttgac
    38941 tttgcttaaa accttagcta acgaaaagga atatcgccat ttagacgaag atatagctac
    39001 tgtgcctgat ttgcaagtag ctccacctct tacgggcgta aaaccgctat catatagtaa
    39061 gatagatact actccgcttg ttcaagaaat ggttaaagaa acgaaacaac tattagaagc
    39121 ttcagcaaga ttagctgctg aaaatacaag tcttgtagca gaagcgcttg ttggccaaac
    39181 ctctgaaatg gtagcaagta atgccattgt gtctaaaatc acatcttcga ttactcagcc
    39241 ctcatctaag acatcttatg gctcaggatc ttctacaacg agcaatctca tttctgatgt
    39301 tgatgaaagt actcaaagag ctcttaaagc aggagtcgtt atgttggcag ctgtcggcct
    39361 cacaggattt aggttccgta aggaatctag gtgatgcatt cgttataagc aatcgcatca
    39421 aagaaaaaat tctatttgac atgaagtacc gtctgtgtta ttatattaga cggtactttt
    39481 tacttttggt ctctcaagag tgtacagaga cgtgctgaca attgttgcaa aaagtgcacc
    39541 ggatatgggc tgtcaccaag tgctatatca accaaaaata aaaaaacaca ggagaatgta
    39601 gatgcctaca attaaccagt tggtacgtaa accacgtaaa tctaaaattg aaaaatcaga
    39661 ttcaccagct ttgaacattg gttacaacag tcacaaaaaa gttcaaacta aaatggctgc
    39721 cccacaaaaa cgtggcgttg ctactcgtgt tggaacaatg acacctaaaa aacctaactc
    39781 agcccttcgt aaattcgctc gtgtacgttt gagcaacctt atcgaagtaa ctgcctacat
    39841 cccaggtatc ggacacaact tgcaagagca cagcgttgtt cttatccgtg gcggacgtgt
    39901 aaaagacctt ccaggggtac gttaccatat cgttcgtggc gcacttgata ctgcaggtgt
    39961 tgctgaccgt aaacaaggcc gttctaaata cggtgcgaaa cgtccaaaag gataatagaa
    40021 gggggataag agaaaatgag tcgtaaaaat caagcgccta aacgcgaagt attaccagat
    40081 ccattatata actcaaaaat cgtaacacgt cttatcaacc gtgttatgct tgacggtaaa
    40141 cgtggtacag ctgctactat cgtttacgat gctttcagcg ctatcaaaga agcgacagga
    40201 aatgacgctc ttgaagtatt tgaaacagct atggacaaca tcatgcctgt acttgaagta
    40261 cgcgcacgcc gtgtcggtgg ttctaactac caagtcccag ttgaagttcg tccagaacgt
    40321 cgtacaacac ttggacttcg ttggttggta aacgcatcac gagctcgtgg tgaacacact
    40381 atgaaagatc gtcttgctaa agaaatcatg gatgcggcaa acaacacagg tgcatcagtt
    40441 aagaaacgtg aagacactca caagatggct gaagctaacc gtgcctttgc tcacttccgt
    40501 tggtaatata agatatttta gcgtcaaaca aatgctagcc aaaataggga aattgacgca
    40561 gaaacttcag tttctaggta attttatctt tttggcagac atttgtagct aaaattcaac
    40621 taatataaga tgtgagagtg ttaatcaagt ccaagacaaa ataggaatag tgacgcagaa
    40681 acttcagttt ctaggaacta ttatcttttt gtcagtggtt tgtagctcga actcaatcaa
    40741 taagatacga aggcgtatag aacgcaaagt gaaaatagga aatttgatga agaaaccttt
    40801 gtctctagga aagtttatct ttttcacaca gcgtttagcc tgagttcaat gaataagata
    40861 ccaagcctta taaaggcaat aggtattatc tttaccaaca aatatttaga taacgggtag
    40921 gtcctgccta tccgtttttg ctaaatagtg ctataatgaa agagtaaact aaaaaaatag
    40981 gagaaacaca tggctcgcga attttcactt gcaaaaactc gtaatatcgg tatcatggct
    41041 cacgtcgatg ctggtaaaac aactacaaca gagcgtatcc tttactacac tggtaaaatt
    41101 cataaaatcg gtgaaacaca cgaaggcgca tcacaaatgg actggatgga gcaagagcaa
    41161 gaacgtggta tcactattac ttctgccgct acaacagctc aatgggatgg tcaccgcgtt
    41221 aacatcatcg acacaccagg acacgtggac ttcaccatcg aagtacaacg ttctctccgt
    41281 gttcttgatg gtgctgtaac cgttcttgac tcacaatcag gtgttgagcc tcaaactgaa
    41341 acagtttggc gtcaagcaac tgaatacggt gttccacgta tcgttttcgc caacaaaatg
    41401 gataaaatcg gtgctgactt cctttactca gtacaaaccc ttcatgaccg tcttcaagca
    41461 aatgcacacc caatccaatt gccaatcggt gcagaagatg atttccgtgg tatcattgac
    41521 ttgatcaaga tgaaagcaga aatctatacc aacgaccttg gtacagatat ccttgaagaa
    41581 gatattccag aagaatactt agaacaagct caagaatacc gtgaaaaatt aatcgaagca
    41641 gttgctgaaa ctgatgaaga cttgatgatg aaataccttg aaggtgaaga aatcactaac
    41701 gacgaattga ttgctggtat ccgtaaagca acaatcaacg ttgaattctt cccagtactt
    41761 tgtggttctg ccttcaaaaa caaaggtgtt caattaatgc ttgatgcggt tatcgcatac
    41821 cttccaagcc cacttgacat ccctgcaatc aaaggtgtta acccggatac agatgctgaa
    41881 gaagaacgtc cagcatctga tgaagagcca tttgcagctc ttgccttcaa gatcatgact
    41941 gacccattcg taggtcgttt gacattcttc cgtgtttact caggtgttct taatagcggt
    42001 tcttacgtta tgaacacatc aaaaggtaaa cgtgagcgta tcggacgtat ccttcaaatg
    42061 cacgcaaaca gccgtcaaga aattgaaaca gtttacgctg gtgacatcgc tgccgctgtt
    42121 ggtttgaaag acacaacaac tggtgactca ttgactgatg aaaaagcaaa agttattctt
    42181 gagtcaatcg aagttccaga accagttatc cagttgatgg ttgagccaaa atctaaagca
    42241 gaccaagaca agatgggtgt tgcccttcaa aaacttgctg aagaagatcc aacattccgc
    42301 gttgaaacaa acgttgaaac tggtgaaaca gttatcgctg gtatgggtga acttcacctt
    42361 gatgtccttg ttgaccgtat gaaacgtgag ttcaaagttg aagctaacgt tggtgctcct
    42421 caagtatctt accgtgaaac attccgtgct tctacacaag ctcgtggatt cttcaaacgc
    42481 caatctggtg gtaaaggtca attcggtgat gtttggattg aatttacacc aaatgaagaa
    42541 ggtaaaggtt tcgaattcga aaatgctatc gttggtggtg tggttcctcg tgaatttatc
    42601 ccagctgttg aaaaagggtt gatcgaatct atggcaaacg gtgttcttgc tggttaccca
    42661 atggttgacg ttaaagctaa actttacgat ggttcatacc acgatgtcga ctcatctgaa
    42721 actgccttca agatcgcagc atctcttgct cttaaagaag cagctaaatc agcacaacca
    42781 gctatccttg agccgatgat gcttgtaacg attacagctc cagaagacaa tcttggagac
    42841 gttatgggac acgtgacagc tcgtcgtgga cgcgttgatg gtatggaagc acatggtaac
    42901 agccaaatcg ttcgtgctta tgttccactt gctgaaatgt tcggttatgc aacagttctt
    42961 cgttctgcta ctcaaggacg tggtacattc atgatggtat ttgaccacta tgaagatgtt
    43021 cctaagtcag ttcaagaaga aatcattaag aaaaacaaag gtgaataacc accactaaga
    43081 ggttgaggat aactatccta acctcttttt tagtgtaaca gaacgttata gtacagtttg
    43141 aagttttgga aatctttccc aataaaaaga taaattacag aatagaacat agaaaaaaga
    43201 aagccctgtc ctatatttgg tgggttttga aggctagtag aaagaagctg ccctttatga
    43261 aaatggctaa tttatttgca ttttttctga aatagttata taatagttct gttgaaaggt
    43321 tgttgcagat gactgtaagt taatcttttc acaataggta gggagcattc cctctaaata
    43381 atattctttt gattttcata aggaggaaat cactaatggt agttaaagtt ggtattaacg
    43441 gtttcggtcg tatcggacgt cttgcattcc gccgtattca aaacatcgaa ggtgttgaag
    43501 taactcgtat caatgacctt acagatccaa atatgcttgc acacttgttg aaatacgata
    43561 caactcaagg tcgttttgat ggaacagttg aagttaaaga aggtggattt gaagtaaacg
    43621 gaaacttcat caaagtttct gctgaacgtg atccagaaaa catcgactgg gcaactgatg
    43681 gggttgaaat cgttcttgaa gcaactggtt tctttgctaa aaaagaagca gctgaaaaac
    43741 acttacatgc taacggtgct aaaaaagttg ttatcacagc tcctggtgga aacgatgtta
    43801 aaacagttgt tttcaacact aaccacgaca ttcttgacgg tactgaaaca gttatctcag
    43861 gtgcttcatg tactacaaac tgtttagctc ctatggctaa agctcttcac gatgcattcg
    43921 gtattcaaaa aggtcttatg actacaatcc acgcttacac tggtgaccaa atgatccttg
    43981 acggaccaca ccgtggtggt gaccttcgtc gtgcacgcgc tggtgctgca aatatcgttc
    44041 ctaactcaac tggtgctgct aaagctatcg gtcttgttat cccagaactt aacggtaaac
    44101 ttgacggtgc tgcacaacgt gttcctgttc caactggatc agtaactgag ttggttgtaa
    44161 ctcttgacaa aaacgtttct gttgacgaaa tcaacgctgc tatgaaagct gcttcaaacg
    44221 atagcttcgg ttacactgaa gatccaatcg tttcttcaga tatcgtaggc gtatcatacg
    44281 gttcattgtt tgacgcaact caaactaaag taatggaagt tgacggatca caattggtta
    44341 aagttgtatc atggtatgac aacgaaatgt cttacactgc tcaacttgta cgtactcttg
    44401 agtacttcgc aaaaattgct aaataattag ttataacgaa agagagcttg gtttatgctg
    44461 agttcttttt cgtatacttt aaacactacc ttaaatgtat gattttaacg ttttgaacta
    44521 ttctagatcc tagcataaaa gatattttaa aatagttccc ttaataaact ctatacaaaa
    44581 aggctaagat ggaaggggtg tcttagcctt tttttgtctg acttaaattt ggagagataa
    44641 aaagtaaaat cttatttttt accgtaacgt ttgtactcgt gaataatctt cagagcacgt
    44701 tttctggttt taatattggg acttttcagt cttctgtaag ctgacgataa gtcagttttt
    44761 tctgccatat tatcctccta aatataaatt attaacgtta acaaaaataa gtatagcata
    44821 aaatatttaa ctggtaaagt attttatgac aaattctttt tgaattgaaa aaagacccaa
    44881 ctggcataga aatagttgga tcctttatct tattttaaga agcgttgtaa aaattctttg
    44941 gtacgatctt gtgtaggatt ctcgaaaatt tgttgaggac ttccttcttc agcaatcaat
    45001 cccttatcca tgaagatgat acggtcagaa acatcacgag caaattccat ttcatgggta
    45061 acaataatca tggtcaaccc tgattttgcc aagtcttgca tggttttaag gacctcacca
    45121 accatttcag gatcaagagc tgatgttggt tcatcaaaga gcatggcttc tggattgaca
    45181 gataaggctc tggcaatggc aacccgttgt ttttgccccc ctgataattg ttttggtttg
    45241 gcttgccagt attgttctgt cataccaacc gcattgaggt tttctttagc gatttgttcg
    45301 gcttgtgcac ggtctctttt gaggacggtg gtttgagcga cgatagcatt ttccaataca
    45361 tttaggtttt caaacaagtt aaaggattgg aaaaccatgc ctagtttttc acggtagtga
    45421 gtcaagttgt agtgttcagc aaggacatct tcaccatgaa agaggatttg accggcactt
    45481 ggctcttcca aaagattgat cgagcgcagg agggttgatt ttccagaacc agaagaaccg
    45541 ataatggaaa tcacttctcc cttgttaaca gaaagggaga tatctttgag cacttcattg
    45601 ctgccgtaag attttttgag gtttttgatt tcaataattg agttagacat ttgagacctc
    45661 cgcaatctgc atttggtttg ctccagtggt gtaagtatcg gcatcgaaac ggcgttcaat
    45721 atgacgaaga atacgtgtca ccgtgaaggt aagaacaaag tagataatgg cgataatcgt
    45781 aaaggtttgg aaatattggt aggtttgtgt ggctacggta ttacctgaga agtaaagttc
    45841 cacaacagag ataacattca aaacagaagt atctttgata ttgatgacaa actcattacc
    45901 tgttgctggt aaaatgttgc gaacaacttg tggtagcacg attttacgca tggtttgtcc
    45961 gtgagtaaag ccaagagcag ttgctgcttc gaattgacct ttgtcgacag cgaaaatacc
    46021 accgcgaaca atttcactca tataggcacc cgtattgata gatacgataa aaatagccgc
    46081 tagggtacgg tcgatcgaaa taccaaaggc ttgcgctgtt ccgtagtaga taaccataga
    46141 ttgaacaatc ataggtgtcc cacggaagat ttcgatataa atagtgagta accaaccaaa
    46201 gagtttttgt cccaaggcgg ctactttatg cttagcttta ggagctgtac ggaaaatacc
    46261 gattaataat ccaataaaga gacctgtaat ggttccgacc atggaaatca gaagggtcat
    46321 tccagttcca cgtaagaatt gcttccagtt acctttaaaa atagcccaca tttggcctag
    46381 aaatgatgct ttagcatctt cggctttctt ttccacgggt tgtttggtaa ccatatcatc
    46441 catcagggcc atacgatccg tttgagaaaa tccttcaagc acttggttga cagttgccat
    46501 acgatcgtca ttttttttca ttccgacagc gatagcagca tctgattcag caacagcaaa
    46561 ccctttttta agagtgatca ttttcaaacg gctatcagca gcttcagcag tcatggcttc
    46621 aggccgttca gaaatatagg catcgataac acccgaagta agggcttgtc gcatttgaga
    46681 gaaatccccc attggtgttt gtaacttagc accttttagt tgagttaaga gattgacatg
    46741 ccaaacgcct tgctgggcag ttactttagc tccagaaaaa tccttgaggc tttttgcctc
    46801 agcatatttg ccattagcag ttacgactag aacaggttgg ctagtgtagt agctgtttga
    46861 gaagctaatt tcgtttctac gctctttggt aggactcata ccagcagcga tcatatcgat
    46921 ttttccagaa gttaatgctg gaattaaacc ggtccaagag gtcttaacga ctaacagttc
    46981 tttgttcata gctttagcga cttttttagc gacttggaca tcgtaaccgt tggcgtattg
    47041 gctagttccc tcaataggga cagccccgtt tgaagcgtca tcttgagtcc agttaaaagg
    47101 agcataggct gcttccattc cgactcttaa atattggttt gcttgagccc ggctcattcc
    47161 tccaaacaga agggccaagg cgaccaaaca gctaaggatt agctttttca tataggtctc
    47221 ctgtttcaaa aatagtattc agacctattt tacagcaatt tgcatcctat ttcaatatat
    47281 tatcagtgaa taggttgaaa tatggaaaaa tattcaaaat aatgattaaa aataagatga
    47341 aggacttggt ttaggttttg tcatctcctt aaaatatggt aaaatgaggg cagaaagagg
    47401 atgttgccat gaaaaaaatt ttgatgacgc ttgtgctctg cttcagtctt ttagggatac
    47461 gaataaaagc agctgatgta gactatagca tcaccaacta tgaaggtcag ttactgttat
    47521 caaaagaaaa tactgctcgg tttgagcaaa aagtaaccta tcaatttgac acttcttata
    47581 acggccagta tatttcgctg ggccggacag gtcatttgcc agcgggcttt gctattgacc
    47641 aaaagcctaa agttgaggta tatcagaatg gtcaacaggt acctgttagt caagagttta
    47701 gtgaccttgg agatggctat cgtttaaaac tttataatgc tggccaagct ggtgataagg
    47761 ttgacgtcaa ggttatctgg caactgcacc accttttaac agcttatcaa gacgtggcag
    47821 agctgaattg gacaccgatt agtgattggg acaaaatatt agaaaaggtg agtttgaccg
    47881 tcactacccc aactgatatt caggattcta atctatgggc tcacagagga tattaccaaa
    47941 agaaacctca agtgttaaaa gaaggtaaca gtcgctatca gattaatgcc aaaaatgtct
    48001 cagggcaatt ggaattgcat gcttattggg ataaaaaagc attattggga gaagaaccag
    48061 ttgatgtttc aacgagtaaa aagaataaaa ttgtagcgtt agaaactaag atttccagac
    48121 gaagggcctt gttacagctg ctatttggca aagtcattcc tctggtagag gtaggttttc
    48181 ttctttggca gttaatacag tttacaagat taaagaaaca attcaatcgt tatcatttgg
    48241 ccaaccatac agatcacagt tacgaagtcc ctgaagacct ttcgcctctt gtgttggcac
    48301 aagcgattta tggacagagt tttgcctatt tatcccctac agcatcagaa agccagaaat
    48361 tattgatccc taaaggagtg acctttgagg cccttgttca agctaccttg ttggatctga
    48421 tcgaccaaaa ggtgctttta ttaacgaaag aagaagggaa agcttatctt gaaatcagtc
    48481 agttagatcg tgtgacagat gaggaagctg ccttcttaga tatggctttt ggaaacaagg
    48541 tgacattgcc ggtggatcaa ttgtttagtc aataccatta tgatgctgat accattaaac
    48601 aattaaagaa aacgtacaaa ggtaaaaagc tcgagcaaga agtccgtcaa tcgtctgagc
    48661 aggtgattaa ggcgatgaaa aaagcgtcgg cagctattac aaacaatgtc ctagaaacta
    48721 tcaaaaagtt aaacttacca gatacttatc gtcaaatgac cccggcagag aaacgaaaaa
    48781 gcaatagtgt ccagggacta ggttgtttgt tgcttattct aaatagtggt ttattgattt
    48841 acttggctat taaagaaagt gggttggccc tcatttacct tgctttaatg gtgctaacga
    48901 tgtgccttgg cttttacatt agcctgaagt tagatcaata caagaaattg ggtattgaaa
    48961 cacctgaggg gggtgttcgg ttacatcaat ggcagagctt taaaaacatg atacgagaca
    49021 ttgacaaatt tgaggatgtt gctattgaag gtttggttgt ttggaaccgt gttttggttt
    49081 atgccacctt atttggttac gctaagaaag tggaacgcta tttgaaagtc catcgtattg
    49141 ccttacctga ggtttaccaa gctgttcgac caggtgaatt atcaatggta atgtatgcta
    49201 cgacaccaac ctttgtgtct agcttgtctt cagctacaac ttcctcaaat ttctcagtct
    49261 cttccggagg cgggattagt ggtggtggtg gcttctctgg cggtggcgga ggaggcggcg
    49321 gcggtgcctt ttaaaaaagc tgcttggcat taatcacagt ttagaaaatc acaataagag
    49381 tggttaataa ggagaaaaca tgttaataat cgaattgcta aaagccattt tctttggcat
    49441 cattgaggga atcacagaat ggttaccagt ttcaagcact ggtcacctca ttttagtgca
    49501 ggaatttatc cgactaaatc aggataaggc ttttatagaa atgtttaata tcgttattca
    49561 actaggggcg attatcgctg ttatgttgat ttattttgaa cgtctcaatc ccttccaacc
    49621 tgggaaaaca gcaagagaag tacagcttac ctggcaatta tggctaaaag tggtgattgc
    49681 gtgtattcct tctattttaa tagcggttcc tcttgataat tggtttgaag cacattttta
    49741 ttttatggtt ccgattgcca tcgctttaat cgtctacggg attgccttta tctggattga
    49801 aaaacaaaat gctcaacaag aacctgccgt cactgactta gctagaatgt cttacaaaac
    49861 agctttcttc attggttgtt ttcaagtctt aagtattgtg cctggtacta gtcgatcagg
    49921 ggctaccatc ttaggagcta ttattttagg aactagtcga acagtggccg ctgatttcac
    49981 cttctttttg gccattccta ccatgtttgg atatagtgga ttaaaggctg tgaaattttt
    50041 tcttgatggc catcaccttg attttgcaca agtccttatt cttttagtgg ctagcttgac
    50101 cgcttttgtg gttagtttat tggcgattag gttcttgaca cattatgtta agaaacacga
    50161 tttcaccatt tttggaaaat accgtattgt gttaggaagc cttttactta tttatagctt
    50221 ctttaaattt gttttttaaa cttacatatc gtttaggatg ttgcgacaga ccttggggac
    50281 tgtcgctttt taaatttcct tttgtagacg aggagttagt cataaattgc gaaattacag
    50341 catttctagt ataataaaat gactacgcgt gcgaggtatt gagaatggaa atgaaacaaa
    50401 ttagcgagac aacgctaaaa ataacaatta gtatggacga tttagaagaa agaggaatgg
    50461 agttgaaaga tttcttgatt cctcaagaaa aaacagaaga gtttttctat tctgtgatgg
    50521 acgaactcga tcttccagat aattttaaag atagtggtat gcttagtttt cgagtgactc
    50581 cacgcaagga ccgtctagat gtttttgtta ccaaatctga gataaataaa gatattaatc
    50641 ttgaagattt agcagagttt ggtgatatgt cccaaatgac tccggaagat tttttcaaga
    50701 gcttggagca atccatgcgt gaaaagggag atgtcaaagc tcatgaaaaa ttggaaaaaa
    50761 ttgaagagat aatggaagat gttgttgaag ccactctagc taatcagtct gaagcggttg
    50821 atccatcaac taatcatgag tcagaacctt tagactatgt ccattatgta ttggattttt
    50881 caacgattac agaggcagtg gcttttgcta aaacgattga tttttcgata gaagcttcag
    50941 agttatataa ggggagcaac tgctaccata tgactatttt attagatgtt cagcaacaac
    51001 catcttattt tgcgaatgtc atgtatgcga gattgattga gcatgcaaac cctggatcaa
    51061 aaacaagagc ttatttacaa gagcatggct tacaattgat gcttgatggt gctgttgagc
    51121 aattacaaaa gattgagttg ggataaaata gtatgttttc attcacaata gattatgtcc
    51181 ttgttctgat aggggctttg ttaatgtcct tattcttaac ccctcttgtt cgctttttag
    51241 cctttcgtgt gggtgcagta gacaatccca atgccagacg ggtcaataag gttccgatgc
    51301 caaccagtgg tggattagct atttttatgt cttttttagt agcaagtttg ggacttattc
    51361 cgattgcttc taaaggcgcc atgttttttg gtcagaccta cttcagttat attttacctg
    51421 tcgtgattgg tgctacagta attaccctta ctggtttttt agatgatttg tatgagttaa
    51481 gtcctaaatt aaagatgttt ggtattctaa ttggtgcagt gattgtctgg gcttttaccg
    51541 actttaaatt tgatagcttc aaaattcctt ttggagggcc gttgttagtt tttggtcctt
    51601 tcttaacctt attcttaaca gtcctgtgga ttgtttccat cactaatgct attaacttga
    51661 ttgacggttt ggatggtttg gttagtgggg tctctattat tagtttagtg accatggcta
    51721 ttgtatctta tttcttttta cctcaaaagg atttcttttt gacgttaacc attttggtct
    51781 tgattgctgc tattgcagga ttttttcctt ataattacca tccagctatg atttatttgg
    51841 gtgacacagg agccctcttt attggcttta tgataggggt tttgtctctt caaggattga
    51901 aaaattcaac ggctgtggct gtggtgacac ctgttattat tcttggtgta cccattatgg
    51961 ataccatcgt ggctattatt cgacgtagtt tatcaggtca aaaattctac gagccggata
    52021 agatgcacct gcatcatcga ctcttatcaa tgggctttac tcatcgagga gctgtcttag
    52081 tagtttatgg tattaccatg cttttttccc ttatttcttt acttttaaat gtttctagtc
    52141 gaattggtgg cgtcctcttg atgcttggac ttttatttgg tttagaagtt tttattgaag
    52201 gattggagat ctggggtgaa aagcgaacgc ctttgtttaa cttgttaaag tttattggta
    52261 atagtgatta tcgtcaagca atgcttctga aatggaaaga aaagaaggat ttgaaacact
    52321 aaaaaagccg agtaaggctt tttttgctat aatagatgca gtgaccatta taaaaaaagc
    52381 agtgcaaatg acactgtctt ttcttgagat ggtatagatg acagagaaaa taaggggtgt
    52441 atcatgtcaa ttcttgagat taataattta catgtttcaa tagaaggtaa agagattttg
    52501 aaaggggtta acctaactct taaaactggg gaagtagctg ccattatggg gccaaatggg
    52561 acaggaaagt ctaccctttc agcagctatt atgggaaatc ctaactacga agtgacccaa
    52621 gggcagattt tgcttgacgg ggtcaatatt ctcgatctag aagttgatga gcgtgcgaga
    52681 ctgggacttt ttctcgccat gcaataccct tcagaaattc cagggattac caacgctgaa
    52741 tttatgcgtg cagcaatgaa tgccggtaag gcagatgagg ataagatatc cgtgcgagat
    52801 tttatcacca aacttgatga gaaaatggct ttgttaggta tgaaagaaga gatggcagag
    52861 cgttacctca atgaaggttt ttctggtggg gagaaaaaac gcaatgaaat tcttcaattg
    52921 ctcatgttag agcctaaatt tgctttgcta gatgaaattg attctggtct tgatattgat
    52981 gccctaaaag tagtctctaa aggggttaat gagatgcgtg ggaaagactt tggagctatg
    53041 attatcaccc actatcaacg tttgttgaat tacattaccc cagacctagt tcatgttatg
    53101 atggatggtc gtattgtctt atctggtgat gctgccttgg ctactcgtct tgaaaaagaa
    53161 ggctacgcag gtattgcaca ggatctggga atcgagtata aggaagaaag ttaagttttt
    53221 ggagacaatt actttagctt tctacaaaaa gctaggtgat gttctatata cccagccaat
    53281 ttaaaaacca gagacaaagg attgacagat gacaaaagaa aaactagtgg ctttttcgca
    53341 agtccacgct gagcctgctt ggctgcaaga acggcgttta gcggcattag aagccatacc
    53401 agaattagag ttaccaacca tcgaaagggt taaatttcac cgttggaatc taggagatgg
    53461 tactttaaca gaaaatgaaa gtctagctag tgttccagat tttatagcta ttggagataa
    53521 cccaaagctt gttcaggtag gcacgcaaac agtcttagaa cagttaccaa tggcgttaat
    53581 tgacaaggga attgttttca gtgattttta tacggcgctt gaggaaatcc cagaagtaat
    53641 tgaagctcat tttggtcagg cgttagcttt tgatgaagac aaactagctg cctaccacac
    53701 tgcttatttt aatagcgcag ccgtgctcta cgttcctgat cacttggaaa tcacaactcc
    53761 tattgaagct attttcttac aagatagtga cagtgacgtt ccttttaaca agcatgttct
    53821 agtgattgca ggaaaagaaa gtaagttcac ctatttagag cgttttgaat ctattggcaa
    53881 tgccactcaa aagaccagcg ctaatatcag tgtagaagtg attgctcaag caggcagcca
    53941 gattaaattc tcggctatcg accgcttagg tccttcagtg acaacctata ttagccgtcg
    54001 aggacgttta gagaaggatg ccaacattga ttgggcctta gctgtgatga atgaaggcaa
    54061 tgtcattgct gattttgaca gtgatttgat tggtcagggc tcacaagctg atttgaaagt
    54121 tgttgcagcc tcaagtggtc gtcaggtaca aggtattgac acgcgcgtga ccaactatgg
    54181 tcaacgtacg gttggtcata ttttacagca tggtgtgatt ttggaacgtg gcaccttaac
    54241 gtttaacggg attggtcata ttctaaaagg cgctaaggga gctgatgctc aacaagaaag
    54301 ccgtgttttg atgctttctg accaagcaag agccgatgcc aatccaatcc tcttaattga
    54361 tgaaaatgaa gtaacagcag gtcatgcagc ttctatcggt caggttgacc ctgaagatat
    54421 gtattacttg atgagtcgag gactaaatca agaaacagca gaacgattgg ttattagagg
    54481 attcctagga gcggttatcg ctgaaattcc tattccatca gtccgccaag agattattaa
    54541 ggttttagat gagaaattgc ttaatcgtta agacctactg ccaaaaagaa agaggttagt
    54601 attgctagac gcaaaagaca tcaaacaaga ctttcaaatc ttaaatcaac aagtcaatga
    54661 tgaacccctt gtttatttgg ataatgccgc caccacacaa aaaccggcgc ttgttcttga
    54721 ggctttgcaa tcctattatc aagaagataa tgctaatgtc caccgaggag ttcatacctt
    54781 ggctgaacgt gcaacgcaca aatatgaggc cagtcgccag caggttgctg actttattca
    54841 tgctaaatca agcaaggaag tgctctttac cagaggaaca acaaccagtt tgaattgggt
    54901 tgctcggttt gcagagcagg tcttgacgcc agaagatgag gtgttgattt cgattatgga
    54961 gcatcatgcc aatatcattc cttggcaaca agcctgtcaa aaaacaggag caaggttagt
    55021 ctatgtttat ttaaaagatg gccaacttga catggacgat ttggcaaaca aattgacgac
    55081 aaaaacacgt tttgttagcc tagtacatgt ctccaatgtt cttggttgca tcaatcccat
    55141 taaagaaatt gccaagctgg cacatgctaa aggagcctac cttgttgttg acggtgccca
    55201 gtcggttcca catttggcta ttgatgttca agacttggat tgtgatttct ttgctttttc
    55261 agctcataag atgttggggc caacaggttt gggtgttctt tacggcaaag aagagctttt
    55321 gaatcaagtg gagcctcttg aatttggcgg agaaatgatt gattttgttt acgaacaaga
    55381 ggccacttgg aaagaattgc cctggaagtt tgaagcagga acacctcaca tagctggtgc
    55441 tattgggcta agcgcagcca tttcttacct tcagagacta ggcatggctg atatacatgc
    55501 gcatgaagca gaactaatag cctatgtttt gccgaaatta gaagctattg aggggcttac
    55561 catatatgga ccaagccagc ctagtgcaag atctggtctg atttctttta atctggatga
    55621 tttgcatcct catgacttgg caacagcctt ggactatgaa ggtgttgcag taagagcagg
    55681 acaccactgc gcccaacctc ttcttagtta tttaggtgta ccagcaactg ttagagcaag
    55741 tttttatatc tataacacca aggcagattg tgaccgttta gtcgaagcaa ttctaaaagc
    55801 aaaggagttt ttcaatggca ctctctaaac tgaaccatct atacatggct gtggtagcgg
    55861 accattcgaa acgtccacat catcatgggc aactagatgg cgtagaggct gttcaactga
    55921 ataatccgac ttgtggtgat gtgatttctt tgaccgttaa atttgacgaa gataaaattg
    55981 aagatattgc ttttgcaggc aacggctgta ccatttccac agcttcatca agcatgatga
    56041 cagatgctgt tattggtaaa agtaaagaag aagcactcgc gttagctgat attttttcag
    56101 agatggtaca aggacaggaa aatcctgctc aaaaagagct aggtgaagca gaattgttgg
    56161 caggagttgc aaaatttcca cagcgtatca aatgctctac cctagcttgg aatgctctca
    56221 aggaagccat taaacgaagt gccaatgctc agcacctcac ggaccaaaat gtaaaggaag
    56281 ggaaaaatgt ctgatataaa tgagaaagta gagccaaagc caattgactt aggggactac
    56341 caatttggat ttcacgatga tgtagagccc atttattcta caggaaaagg attgagtgag
    56401 gcagtagttc gcgaactatc agctgccaaa aatgaacctg agtggatgtt ggagtttcgt
    56461 ttaaaatcct tggaaacctt taataaaatg ccgatgcaaa cctggggagc agacttatca
    56521 gatattaact ttgatgatat catttactat caaaaagcat ctgataagcc agctcgttct
    56581 tgggatgatg ttccagaaaa aataaaagaa acctttgatc gtattggaat tccagaagca
    56641 gaacgtgctt atcttgctgg agcatcagct cagtatgagt cagaagtggt ttaccataac
    56701 atgaagggtg aatttgaaaa gctagggatt atctttacag ataccgattc cgccctcaaa
    56761 gaatatcctg atttgttcaa acaatacttt gccaaactgg ttccgccaac agacaacaaa
    56821 ttagcagccc tcaattcagc agtttggtct ggtggtacct ttatttatgt tcctaaaggg
    56881 gtcaaggtag atattccttt gcaaacttat ttccgcatta acaatgaaaa tactggtcaa
    56941 tttgagcgga cattgattat tgttgatgaa ggagcaagtg ttcattatgt tgaaggatgt
    57001 acagctccca cttattcaag taacagctta catgctgcta tcgttgaaat ctttgcgctt
    57061 gacggtgcat acatgcgtta taccaccatt caaaactggt cagacaatgt gtataatcta
    57121 gtaacaaaac gtgcacgcgc ccttacggat gcaacagtgg aatggattga tggcaatcta
    57181 ggagctaaaa ccaccatgaa gtacccttct gtttatcttg atgggccagg tgcgcgtggc
    57241 accatgctgt ctattgcctt tgctaacgca ggccaacacc aagatacagg ggctaaaatg
    57301 attcacaatg ctccacatac atcatcatca attgtgtcaa aatcaattgc caagtctggt
    57361 ggtaaagtag attatcgtgg ccaagtgacc tttaacaagc aatctaaaaa atccgtttcc
    57421 catattgaat gtgatactat tttgatggac gatatttcta aatcagatac gatcccattt
    57481 aacgaaattc ataattcaca ggtggcgtta gaacatgaag ccaaagtgtc taagatttct
    57541 gaagaacaac tctactatct catgagccgt ggcttatcag aaagcgaagc cacagagatg
    57601 attgtcatgg gatttgtgga gccttttacc aaagaattgc caatggaata cgcggtcgaa
    57661 ctcaatcgat tgatttccta tgagatggaa ggttctgtcg gttaattgca ttttctctta
    57721 tccatctgaa agatctttga gataggattt tatgagttgt agtactaacc ccaagtggtt
    57781 agtttttagt tgccttaaac acgtaagata acatatcaaa aacctctgtg ctttgacaga
    57841 ggtttttgat aattcattat tggcgtccca ttgcaaagac aacgaggctt agtaaaagga
    57901 tagtaattat aaagatagct aagcaaataa gcaagaaagt atggttgtga ttcataaaat
    57961 cttcgactct ttccaagtac gattgctttt tagtggcttt gaagtgctgc tgtttaggtg
    58021 atgtttcttt tttggtttgt ggcactaatt tttcgagttt ttggcgtgct tttttggata
    58081 aggtcttact atctttaaac cctttctcag tcaaggcatt aacgaaagga tgtctataaa
    58141 actctccgtt ttgatctgac caatctccga cccccatgac aatagtaatg agtcgagttt
    58201 tgcctctttt ggcagttatc atggcgttaa aagcagcgct gggactagaa cctgttttta
    58261 atccatcaac tccttttata ccaaattgat tatctgggag agagtggtta taggtgtgaa
    58321 attcttcttc atatggcgtt cctaccatag tgtgcacaac agatttattt gtaaaggaga
    58381 taatttcagg gtattttttt aagaaggcat agagtaactt ggacaaatct cgagcggtcg
    58441 taatatttga agcagataaa tcatatttag taggattata ataaccttga aaagcttgtg
    58501 ctgctgcacc actagcgttt gaaaaatgag tgttagtcat gcctaattgt ttggctgtgg
    58561 cattaatacg atcgataaac gcagaagcat cattgtttga taaataattg gcaatcataa
    58621 cagttgctgc atttgatgaa ggcacagctg tcatagtaat aagatcacga ataggataag
    58681 ctactccagc gacgatatta ttattgctaa tctcataaat gttagcgata gcttgatcgg
    58741 ttggagttgc cgtaatagta gtgtccatcg taatttttcc cttagcgagc tcttcaaata
    58801 aaatgtaaag cgtaaacatc ttagacatac tagcaggatc cctaggaata tcaatattat
    58861 cttgccaaag aatatctgaa ctatttgcat caacgacaat agaagatttt ggtcgattaa
    58921 cctcactaac tgtgtagcct gcttgccttg taatatccat gacatcttcg gcgtggacaa
    58981 gaggcatcat cgaaaagcaa ataaaggtaa aaatagttag tataattctt ttggtcaatt
    59041 tccgactcct ttaaatgtaa tgcattttca gtatatcact ttgctaatac aatgtgaagt
    59101 ttttttgaaa aattgttagg attggcctag tttgcttaaa taaaaatgaa aaagactgca
    59161 gaagtactct gtcagtcaat gtcatacaaa aagcattgtg ttattctata aagaggtatt
    59221 gacatacctc acaaaacggt tccaccagac ctttaaaaag aaacttttag aaatgttttt
    59281 ttgaaggata agattgatag aaggaggagt atccagataa ccttgtccaa taagatgttt
    59341 atcttgaagg gttgctctac ctaagacttg tccctttgat agaggtgcga tcattgtgga
    59401 tgatttctta gtaatatgga cggtattttt ggtctttgta tgtattggtt tgataaaaaa
    59461 taaactattt tgggctacaa gtttgacagt tttttcagga ctgtctaaga cagataacgt
    59521 ttttactggt ttattatttt caattaactg gactttttga aaattaatta aaaggtactg
    59581 caacaattga ttggttgttt taaatatagc taaatcatcc tcgtggcttt gatcagcatt
    59641 taaaactact gtaataaccc tcatttgatt ttcgacacta gtagctacaa aagaagcacc
    59701 ggctttttta gaataaccaa caaaaagacc atccacgcct tctcgataac aaggcatgcc
    59761 tttaagcatg taattataac tgtaaatggt ttgtccatca aaaatagtgg aggatttgct
    59821 agataatttc agtacttctg gaaattctaa taagagatgc ctggcaataa tagctaaatc
    59881 agtggcgcaa aaacaatttt catcatctgg ttctgtatta ggataagtat tagctcctaa
    59941 aaaatggtta gttaagccag ttgaattgac gacctttgca tcggaaatgc cccattgtct
    60001 taattgtttt ttcattttgt caacaaattt gggttcggtt ccgcctattt tttcagctaa
    60061 agcaatagcg gggctattgg cgttattaac aactaacgca cttaaaagtt ctttaacggt
    60121 atattttctc ttatcaagag gaacgttact aatagtatag tttgtagtga gttcataagg
    60181 gtagttagaa atagttacag gactatccca atttagcttg cccttagaaa cttctttgta
    60241 aaccagatag gttgtcaaga gcttactgac tgaggcgaca gggacaactt ctttagcatc
    60301 tttttcgtat aaaactttgc cactttcaag gtcaacggca atcgcatgct tagcagttac
    60361 cgaatactct tcaccgctaa cagtgcttgc tgcaaaaaat aaggcgatga ccactaggga
    60421 aattaatcgt ttgatcattt atagattatc cttactcaag tattattttt ttaattatac
    60481 catatttttg tctaaggtaa tgacttacct cacaagagta gtgatgtaat aaaacgctac
    60541 catgagagaa tgacaatctt tattaaacta attgaaacct cattaaaaaa ggagtgtaac
    60601 gctttcatat agataaatgt ataaaataaa gaaaattcta cgaaatattc agataatttt
    60661 tcatttcatt attttcttta agaaagtttt atgatataat gtcttcaatt aaccaatttc
    60721 atttagcaat tgccaaaaaa tgaaaaataa agtttagggg tgacttttat gaagaaaagt
    60781 aaatggttgg cagctgtaag tgttgcgatc ttgtcagtat ccgctttggc agcttgtggt
    60841 aataaaaatg cttcaggtgg ctcagaagct acaaaaacct acaagtacgt ttttgttaac
    60901 gatccaaaat cattggatta tattttgact aatggcggtg gaacgactga tgtgataaca
    60961 caaatggttg atggtctttt ggaaaacgat gagtatggta atttagtacc atcacttgct
    61021 aaagattgga aggtttcaaa agacggtctg acttatactt atactcttcg cgatggtgtc
    61081 tcttggtata cggctgatgg tgaagaatat gccccagtaa cagcagaaga ttttgtgact
    61141 ggtttgaagc acgcggttga cgataaatca gatgctcttt acgttgttga agattcaata
    61201 aaaaacttaa aggcttacca aaatggtgaa gtagatttta aagaagttgg tgtcaaagcc
    61261 cttgacgata aaactgttca gtatactttg aacaagcctg aaagctactg gaattcaaaa
    61321 acaacttata gtgtgctttt cccagttaat gcgaaatttt tgaagtcaaa aggtaaagat
    61381 tttggtacaa ccgatccatc atcaatcctt gttaatggtg cttacttctt gagcgccttc
    61441 acctcaaaat catctatgga attccataaa aatgaaaact actgggatgc taagaatgtt
    61501 gggatagaat ctgttaaatt gacttactca gatggttcag acccaggttc gttctacaag
    61561 aactttgaca agggtgagtt cagcgttgca cgactttacc caaatgaccc tacctacaaa
    61621 tcagctaaga aaaactatgc tgataacatt acttacggaa tgttgactgg agatatccgt
    61681 catttaacat ggaatttgaa ccgtacttct ttcaaaaaca ctaagaaaga ccctgcacaa
    61741 caagatgccg gtaagaaagc tcttaacaac aaggattttc gtcaagctat tcagtttgct
    61801 tttgaccgag cgtcattcca agcccaaact gcaggtcaag atgccaaaac aaaagcctta
    61861 cgtaacatgc ttgtgccacc aacatttgtg accattggag aaagtgattt tggttcagaa
    61921 gttgaaaagg aaatggcaaa acttggtgat gaatggaaag acgttaactt agctgatgct
    61981 caagatggtt tctataatcc tgaaaaagca aaagctgagt ttgcaaaagc caaagaagct
    62041 ttgacagctg aaggtgtaac cttcccagtt caattagatt accctgttga ccaagcaaac
    62101 gcagcaactg ttcaggaagc ccagtctttc aaacaatctg ttgaagcatc tcttggtaaa
    62161 gaaaatgtca ttgtcaatgt tcttgaaaca gaaacatcaa ctcacgaagc ccaaggcttc
    62221 tatgctgaga ccccagaaca acaagactac gatatcattt catcatggtg gggaccagac
    62281 tatcaagatc cacggaccta ccttgacatc atgagtccag taggtggtgg atctgttatc
    62341 caaaaacttg gaatcaaagc aggtcaaaat aaggatgttg tggcagctgc aggccttgat
    62401 acctaccaaa ctcttcttga tgaagcagca gcaattacag acgacaacga tgcgcgctat
    62461 aaagcttacg caaaagcaca agcctacctt acagataatg ccgtagatat tccagttgtg
    62521 gcattgggtg gcactccacg agttactaaa gccgttccat ttagcggggg cttctcttgg
    62581 gcagggtcta aaggtcctct agcatataaa ggaatgaaac ttcaagacaa acctgtcaca
    62641 gcaaaacaat acgaaaaagc aaaagaaaaa tggatgaaag caaaggctaa gtcaaatgca
    62701 aaatatgctg agaagttagc tgatcacgtt gaaaaataaa acgatgttca aaagaacttt
    62761 ctcgtttatg tgagggagtt cttttgaact attgaggata actatgaaaa aatacatttt
    62821 aaaccgtatc atgcgatcgt tagtgtcggt agttttggta acggctttaa catacaccat
    62881 cgtatatact ctagtaccta ccagctttat ctttaaacaa gaccctaatt ataataaaat
    62941 gacaacaaca ccagataaaa aagtagcgta tgaaaatcta acttttcaac gtatgggtta
    63001 tgtcaattat ttttcaagca aagaattaaa agataatgct tctaaagtag atagtagtgt
    63061 aacgacagaa gcaactagtg ctaacaaagc tgtctatgag aagtatattg attctcttgg
    63121 caatggctgg cagctaaaac gcttccccac tagcaaacag ttttatgcaa ttcgcaatat
    63181 tcctatttac gaacgtgttt ggaacttttt ctcaaatcta gttgttattg atcacccttg
    63241 gaagattcag gataaagata atccaaaatt agctaggtat attcgtctag aaaaagataa
    63301 atcagttggc tggtcacttg ttggttcggg gacaaaacat aaatatctcc tctatactaa
    63361 cggaaaattt ccttatcttc accaaaactt tgttacccta aacttaggaa catcttatcc
    63421 aacatacagc aatattcctg ttcttcaggt tatttcacaa gggcaaggac gaacagctct
    63481 tcaagatgtg accttcccat caggtgtcac taagaaatcg tcagtggata tctatagccg
    63541 tagctacaaa aatccaaaat cattggatga tatcaccaag gtaaactatg gtaagggaga
    63601 ttcctacact aaaaccatca ataattatgt cgacccatca atgattcaca attcttttgt
    63661 aattggtttt tttggtgtta tgttttccta tatcgttggt ttgcctcttg gtttatttat
    63721 ggctcggttt aaaaatacct attttgaccg tttctcaaca gcgaccatga ccttcatgct
    63781 tgctttacca agtattgctg ttatctatgt tgttcgcttc ctaggtggca tggttggttt
    63841 accagatagt ttcccaatgc tgggggcatc tgatcctaaa tcttatattt taccagccct
    63901 tattttagga attttaaata ttccaactac ggttatctgg ttccgtcgct atcttgttga
    63961 ccttcaggcc agcgattggg tacgttttgc gcgttcaaaa ggattatcag aatctgaaat
    64021 ttacagaggg catctcttca aaaatgccat ggtcccaatt gtgtcagggg ttcctgcaag
    64081 tattatcctt gctattggtg gtgcaacctt aacagagact gtctttgcct tcccgggtat
    64141 gggtaaaatg ttaattgatt ctattaaatc tgctaacaat tctatgattg ttggattaac
    64201 ctttatcttc actgtcttgt caattgtttc acttttacta ggagatattg tcatgaccct
    64261 tgtcgatcca cgtattaaat tgtcaacaaa aaaaggaggt aagtaatgga atcgattgat
    64321 aaatctaaat ttcgatttgt tgagcgcgat agtgaagcct ccgaagtgat tgatacccct
    64381 gcttattctt actggaaatc agtgtttcgt cagttttttt ctaaaaaatc tacagtcttt
    64441 atgctcgtga ttttagtgac agtcttgatg atgagcttta tttatccaat gtttgccaac
    64501 tacgacttta atgacgttag taatatcaat gacttttcaa agcgttatat ttggccgaat
    64561 gcagagtact ggtttggaac cgacaaaaat ggacaatctc tgtttgatgg tgtttggtat
    64621 ggggcacgta attctatttt aatctcagtt atagcgacac taattaatat caccattggg
    64681 gtagtgttag gagccatatg gggagtttct aaagcatttg ataaagttat gattgaaatt
    64741 tataacatta tctcaaatat cccttctatg cttattatca ttgttttgac ctattcatta
    64801 ggtgcaggat tttggaattt gattctagct ttctgtatca ctggatggat tggtgtcgcc
    64861 tactccatcc gtgttcaaat cttgcgttac cgtgatttag aatacaacct tgctagtcaa
    64921 actttgggaa caccaatgta caagattgct gttaagaacc tcctgcctca attggtttca
    64981 gttatcatga ctatgttgtc acaaatgcta ccagtttatg tatcttctga ggccttctta
    65041 tccttctttg ggattggttt accaaccacc actccaagtt taggacgttt gattgctaat
    65101 tattcaagca acttaacaac aaatgcctac ctcttttgga ttcccttagt aacattgatt
    65161 ttagtatcgt taccactata cattgtcgga caaaacttgg ctgatgccag tgacccacgt
    65221 tcacatagat aggagttaaa atgacaaaag aaaataatgt aatcttaact gccaaagatg
    65281 tggtggtaga atttgatgtg cgtgatcgtg ttttaacagc tatccgtaac gtctcactgg
    65341 aacttgttga aggagaagtc cttgcttttg taggggaatc aggctcaggt aaatctgttt
    65401 taacaaagac ctttacaggg atgttggagt ctaatggacg cattgctaat ggttcaattg
    65461 tctatcgtgg gcaagaattg acagatttaa aaacaaataa agagtgggca aagattcgcg
    65521 gctcaaaaat cgcaacgatt ttccaagacc caatgaccag tcttagtccc attaaaacta
    65581 tcggtagcca aatcacagaa gtgattatta agcaccaaaa agtaagtcat gccaaagcta
    65641 aagaaatggc ccttgattac atgaataaag tgggtatccc aaatgccaaa aaacgctttg
    65701 aagattaccc atttgagtat tcaggaggaa tgcgtcaacg tattgttatc gctattgctt
    65761 tagcttgtcg cccagatatt cttatctgtg atgagccaac aacagccctt gatgtgacta
    65821 ttcaagctca aatcgttgag ttattgaagt cgcttcaacg agaatatcat ttcaccatta
    65881 tctttattac gcacgattta ggtgttgtgg caagcattgc agataaagtg gctgtcatgt
    65941 atgcaggaga aattgttgaa tttggaacag tcgaagagat tttctatgat ccaagacacc
    66001 cctatacatg gagtttgctg tctagcttac cgcagttggc agatgaatct ggtgaacttt
    66061 acgctattcc aggaacgcct ccatcacttt attcaccaat tatcggagat gcctttgcac
    66121 ttcgctcaga atatgctatg gttttagact ttgaaaaagc acctccggcg attaacgtat
    66181 ctgagactca ttgggccaaa acatggcttt tacacccaga ggctccaaaa gttcaaaaac
    66241 cagaagtcat tcaaggtttg catcaaaaaa tcttaaggaa aatgtcacaa caggaggaag
    66301 gaaatgtctg agaaattagt cgaagtaaaa gacctagaaa tttccttcgg agaaggaaag
    66361 aaaaaatttg ttgcagttaa aaatgctaat ttctttatta aaaaaggaga aaccttttct
    66421 ttagttggag aatctgggag tggtaaaaca acaattggtc gtgctattat tggtttgaac
    66481 gatactagtt caggtcaaat tttatacgat gggaaagtaa ttaatggcag aaaatcaaaa
    66541 tcagaagcca atgagctcat tcgtaaaatt caaatgattt tccaagatcc cgctgctagt
    66601 ttgaatgaac gggcaaccgt tgactacatc atttcagaag gtctttataa ctttaatctg
    66661 tttaaaacag aggaagaacg taaagaaaaa attaagaaca tgatggccga agttggtttg
    66721 ctatcagagc atttgacgcg ctaccctcat gaattttcag gaggtcaacg tcagcggatc
    66781 ggtatcgcta gagccctagt aatgaaccct gaattcgtta ttgctgatga accgatttca
    66841 gctttggacg tttccgttcg cgcacaggtt ttaaaccttc tcaaacggat gcaagccgaa
    66901 aaaggtttga cttatctctt cattgcccat gatctttcag tcgttcgctt tatttcagat
    66961 cgtattgcgg ttatccataa aggggttatt gtagaagttg cagaaacaga agaactgttt
    67021 aataacccga ttcatcccta cacccaatct ttgttatcag ccgtgcctat cccagatcca
    67081 attttagagc gtcaaaaaga acttgttgtc tatcatccag accaacatga ttatacatta
    67141 gataagccat caatggttga aatcaaacca aatcactttg tttgggcaaa ccaagcagaa
    67201 attgaaaaat atcaaaaaga attgtaaaag agatgcactg accccaaaag ttggctactc
    67261 tattttaagt aaaggattta gttttgtatt gtagaggact aagtcctttt cgttttattt
    67321 tgatacgttt attgttgcaa taatcgatga taatggtagg tagaacgagt caatacagcc
    67381 gttcttaaaa gaaaatctaa tcagaactcg tctttgtcca ttttttataa tggttttttt
    67441 gtcttcttct ttgcagagat gcttctttca aacggagttc ctcggttttt ttaagtaagc
    67501 aacctcagtt ctgagatatt cattttcttc ttgaagccgc tctaatttag tcatttcttc
    67561 aggtttcttt tggtttacgt cctgtttgtg atggtcttgc tcttgttttc tcaacagtat
    67621 aactgttttt cttatattgt gctattcaac ttgggagagt tcctgcatgt aacaagccat
    67681 aaacaagtga tacttggtat tgtggcgggc cttctatcaa aacgttatcc attatttctt
    67741 gctttatctc tggtggatag taggtatttt tttctttctt aacgatgtct atttcgtact
    67801 ttcatcactt aatttcataa aaaatacccc gaacgttaga tttttttgtc taacgtttgg
    67861 ggtgtagttc aaggcttttt ctcttttttg ttgcacttca ttttacaacg cgggcaaata
    67921 aaaaagtaca aaaaagt
//
LOCUS       DAUCXI010000005        58319 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.005, whole genome shotgun sequence.
ACCESSION   DAUCXI010000005 DAUCXI010000000
VERSION     DAUCXI010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58319
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.005"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            58..1422
                     /gene="ftsA"
                     /locus_tag="VGY43_000287"
     CDS             58..1422
                     /gene="ftsA"
                     /locus_tag="VGY43_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEQ4301509.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            1446..2765
                     /gene="ftsZ"
                     /locus_tag="VGY43_000288"
     CDS             1446..2765
                     /gene="ftsZ"
                     /locus_tag="VGY43_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEQ4301510.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTSAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            2768..3439
                     /locus_tag="VGY43_000289"
     CDS             2768..3439
                     /locus_tag="VGY43_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEQ4301511.1"
                     /translation="MDLLTNKKKIFETIRLSTEAANRTNDSVSVIAVTKYVDSTIAGQ
                     LIEAGIEHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEKIQLVGLMTMA
                     PANASKGSIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            3451..4107
                     /locus_tag="VGY43_000290"
     CDS             3451..4107
                     /locus_tag="VGY43_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEQ4301512.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMN
                     TSGIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            4112..4366
                     /locus_tag="VGY43_000291"
     CDS             4112..4366
                     /locus_tag="VGY43_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEQ4301513.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            4366..5157
                     /locus_tag="VGY43_000292"
     CDS             4366..5157
                     /locus_tag="VGY43_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEQ4301514.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVEDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRLA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGKQKITLSKMIHK"
     gene            5167..5925
                     /locus_tag="VGY43_000293"
     CDS             5167..5925
                     /locus_tag="VGY43_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEQ4301515.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            6198..8999
                     /locus_tag="VGY43_000294"
     CDS             6198..8999
                     /locus_tag="VGY43_000294"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEQ4301516.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRNDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLLNSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNARENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEHESEAFVQLAEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKIIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGVAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESGK"
     gene            complement(9264..9566)
                     /locus_tag="VGY43_000295"
     CDS             complement(9264..9566)
                     /locus_tag="VGY43_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEQ4301517.1"
                     /translation="MRLINTTSSHPELIRNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRALKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(9617..10072)
                     /locus_tag="VGY43_000296"
     CDS             complement(9617..10072)
                     /locus_tag="VGY43_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ4301518.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(10200..12482)
                     /locus_tag="VGY43_000297"
     CDS             complement(10200..12482)
                     /locus_tag="VGY43_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ4301519.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTSNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGDSFLNEESLD"
     gene            12780..13010
                     /locus_tag="VGY43_000298"
     CDS             12780..13010
                     /locus_tag="VGY43_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEQ4301520.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            13137..13823
                     /locus_tag="VGY43_000299"
     CDS             13137..13823
                     /locus_tag="VGY43_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ4301521.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMSQGGNH"
     gene            13823..14557
                     /locus_tag="VGY43_000300"
     CDS             13823..14557
                     /locus_tag="VGY43_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301522.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            14706..16115
                     /locus_tag="VGY43_000301"
     CDS             14706..16115
                     /locus_tag="VGY43_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HEQ4301523.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVT
                     QGKRFDPKGEFIKAYLPQLEHVPEKYLHEPWKMPKYLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKAKIE"
     gene            16293..17987
                     /locus_tag="VGY43_000302"
     CDS             16293..17987
                     /locus_tag="VGY43_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ4301524.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYEEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            18194..19048
                     /locus_tag="VGY43_000303"
     CDS             18194..19048
                     /locus_tag="VGY43_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEQ4301525.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKDGAIVIDVGMNRDDNGKLIGDVALDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            19201..20541
                     /locus_tag="VGY43_000304"
     CDS             19201..20541
                     /locus_tag="VGY43_000304"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEQ4301526.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQLLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDASRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            20519..20734
                     /locus_tag="VGY43_000305"
     CDS             20519..20734
                     /locus_tag="VGY43_000305"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEQ4301527.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            20734..21606
                     /locus_tag="VGY43_000306"
     CDS             20734..21606
                     /locus_tag="VGY43_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEQ4301528.1"
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLENDVGFKP
                     QIITKLIEGLRLNA"
     gene            21599..22426
                     /locus_tag="VGY43_000307"
     CDS             21599..22426
                     /locus_tag="VGY43_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEQ4301529.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFSEGQPVFASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASG
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQKVVAKAHKEFEKHEKE"
     gene            22413..22883
                     /locus_tag="VGY43_000308"
     CDS             22413..22883
                     /locus_tag="VGY43_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ4301530.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            22905..24566
                     /gene="recN"
                     /locus_tag="VGY43_000309"
     CDS             22905..24566
                     /gene="recN"
                     /locus_tag="VGY43_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEQ4301531.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIIKEY
                     QLLTGDDLSSGDLEAELKSLEKQLVAAASELSVSRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            24738..25667
                     /locus_tag="VGY43_000310"
     CDS             24738..25667
                     /locus_tag="VGY43_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ4301532.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFNDDSFISQNETDKMFENLTDDR
                     LLDELDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPHLRSLSD
                     TALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAHYEDR
                     KAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYNRKLGMAVAKRKIA
                     LPQTGEEFSYYPALLGLMILGLTPIMIPKKINN"
     gene            25883..26734
                     /locus_tag="VGY43_000311"
     CDS             25883..26734
                     /locus_tag="VGY43_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ4301533.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILTAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLAKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            26727..27569
                     /locus_tag="VGY43_000312"
     CDS             26727..27569
                     /locus_tag="VGY43_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEQ4301534.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLKKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNIKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKP"
     gene            27547..28134
                     /locus_tag="VGY43_000313"
     CDS             27547..28134
                     /locus_tag="VGY43_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEQ4301535.1"
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            28233..28508
                     /locus_tag="VGY43_000314"
     CDS             28233..28508
                     /locus_tag="VGY43_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEQ4301536.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(28597..29739)
                     /locus_tag="VGY43_000315"
     CDS             complement(28597..29739)
                     /locus_tag="VGY43_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ4301537.1"
                     /translation="MWIEETDNGKFKFRENYKDPYTGTWKPVSVTMEKDNSRAYKAAR
                     KILEQKITEKIAQLKASELLFTELLDEWWAFYKKELKRSSVASLRGNIEEIRETFGIG
                     VKVVNIDPKYVQNYLDNLDCSRNKKERNKSMLNLAFDYAVGLDIIQDNPARRAKLPRV
                     KKTLEDWKKAEEKYLEEDEIKPLLKELYRRPSTYRLGLLAEFISLNGCRIGEAVSIEP
                     CNYESKSRILQLHGTFDHTEGYRNGEKTAPKTLASYRETIMTSRELEILQELEFMNEL
                     EKNTNHRYRDMGYLFTTKNGVPIQTNSFNLALKKANERLEDPITKKLTSHIFRHTLIS
                     RLAENNVPLKSIMERVGHADAKTTAQIYTHVTKKMKSSVADIMENY"
     gene            complement(29863..30381)
                     /locus_tag="VGY43_000316"
     CDS             complement(29863..30381)
                     /locus_tag="VGY43_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HEQ4301538.1"
                     /translation="MAKVIFQDNFLLMGTNYHEKEANKVMAEIGKKSPYWDKDKDFIS
                     DYIKSNFKDIYKYYRVSTKDVEIVREPLNRHDPNAIKVMVNKTFVGYFPADLAKRLTP
                     YVKKSSHYQMEATLTGRGGQYKTLKNDLKTVVTKKKDITYKLRLTILKVDRVSKSKNA
                     GLLESIASWFLN"
     gene            complement(30393..31148)
                     /locus_tag="VGY43_000317"
     CDS             complement(30393..31148)
                     /locus_tag="VGY43_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4301539.1"
                     /translation="MEQLGDRIRKLREGRNMTQTELSEILGMKTYTTVSKWEKNENFP
                     KGKDLKKLAEIFNVTSDYLLGLTDSKLGKITIQNEQPEIVSIYNQLEQPRQEKVLNFA
                     NEQLEEQNKTVSIFDKKSEETEDYITDYVEGLVAAGLGAYQEDNLHMKVKLRSDDVPD
                     EYDTIAKVAGDSMEPLIQDNDLLFIKVSSQVDMNDIGIFQVNGKNFVKKLKRDYDGAW
                     YLQSLNKSYEEIYLSKDDDIRTIGEVVDIYREY"
     gene            31350..31562
                     /locus_tag="VGY43_000318"
     CDS             31350..31562
                     /locus_tag="VGY43_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4301540.1"
                     /translation="MVTIAELRAKHNKMSQRELAKELGVTQTSISNWEKDQTKISGEY
                     LISLALFFDVSTDDILGINKQATQKF"
     gene            31832..32143
                     /locus_tag="VGY43_000319"
     CDS             31832..32143
                     /locus_tag="VGY43_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEQ4301541.1"
                     /translation="MPKAEITYRAVDVNETASHGDYKHLIQQWEGLTVATAKQWATEM
                     RDHPDFKQFVLNPTHRIVFIDYKGFKLFVQWKSRNRYKTKKETLPEMLENIKFEKRVG
                     V"
     gene            32145..32330
                     /locus_tag="VGY43_000320"
     CDS             32145..32330
                     /locus_tag="VGY43_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301542.1"
                     /translation="MNKLELFLLATTVILAVIARVQHEVIKKHNSPENKRKIFREVAL
                     KNSKGWSKKRARGGVVS"
     gene            32834..33220
                     /locus_tag="VGY43_000321"
     CDS             32834..33220
                     /locus_tag="VGY43_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEQ4301543.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHEDNMPIEVVNLAL
                     REAVENNKISWKYINKILVDWYKSGDTTVEKVRDRLQRFDDSKKQRSVTTSNVPSWSN
                     PDYKEPDLKEFALGSMDGIEDGSGDF"
     gene            33201..33434
                     /locus_tag="VGY43_000322"
     CDS             33201..33434
                     /locus_tag="VGY43_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301544.1"
                     /translation="MDQEIFNFFNKQIKKDFGKTASKETFAKFASYCAEGIEKNGVKP
                     IFNWINLYAFGTGMTTAEADRLRIERYKQENAL"
     gene            33431..33571
                     /locus_tag="VGY43_000323"
     CDS             33431..33571
                     /locus_tag="VGY43_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301545.1"
                     /translation="MTKQHRETLIWYRASHQERERLLDFGLVDKARYVTLLRQLRKKY
                     AI"
     gene            33580..33786
                     /locus_tag="VGY43_000324"
     CDS             33580..33786
                     /locus_tag="VGY43_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301546.1"
                     /translation="MTPEQAEKAKIRAKQELETFSIYLDQAIDDLGGVLTSREVFLAA
                     GITYLGAGQTDIHAAVEGLCEQIQ"
     gene            33842..34172
                     /locus_tag="VGY43_000325"
                     /pseudo
     CDS             33842..34172
                     /locus_tag="VGY43_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017991.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            34175..35101
                     /locus_tag="VGY43_000326"
     CDS             34175..35101
                     /locus_tag="VGY43_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEQ4301547.1"
                     /translation="MANQLSTYTHKQFFNAPTVQKAFDDVWKGAGTQFAVSILSVLQG
                     SQSLKSASNKSIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLFNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIEEDNQDST
                     ISTPKDITPQEANSLDDLIGHQNENKDAPNNLKDVTEDLHDEEEKTLTDENKTVLEDT
                     SYPADEVPDFDQETGEVLASEGNLFDNLGDLI"
     gene            35098..35298
                     /locus_tag="VGY43_000327"
     CDS             35098..35298
                     /locus_tag="VGY43_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301548.1"
                     /translation="MIKLVKIEGYYINPEYVVGVWERSALNFDDLDEKVVVIQFVGDR
                     EREEFVFCDTPIDEVIKRLLDD"
     gene            35291..36088
                     /locus_tag="VGY43_000328"
     CDS             35291..36088
                     /locus_tag="VGY43_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEQ4301549.1"
                     /translation="MTSLDLLGKDYYSRESAIRYWSISQYKRFKECEARALAELQGNW
                     TDTRDNTALLVGNYVHSYFESKKAHEEFKAQNGSEMISTRGATKGQLKKDYLVAEQMI
                     DALKSDSNFMAIYQGEKEAAITGFLGEIEFKGKIDCLNVERGYFVDIKTTKGPIDDTI
                     WSGEERVRWFEAYGYILQMAAYKTMLEAKYNKPFEPIIYAVTKETPPDTRAIRIQNVD
                     AMQNELDSLAQSIKRLDDVKKGIEKPKPCGHCEYCRANQLTQRVMIF"
     gene            36453..36848
                     /locus_tag="VGY43_000329"
     CDS             36453..36848
                     /locus_tag="VGY43_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301550.1"
                     /translation="MDELKEKALSKMLDEMNKKHSAAEDAIHNWLSDQDDEELFKGIL
                     DDKKSIKDAMKYCINQAQKQKTGNCAMVDDKTVFGWVRVYFTGKTKKIEPVQATVTVS
                     QENTKVIPKKNKKSKGVVEGQLDLFGALV"
     gene            36845..38191
                     /locus_tag="VGY43_000330"
     CDS             36845..38191
                     /locus_tag="VGY43_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HEQ4301551.1"
                     /translation="MKKNQKIIEGRLKPPKAFFDWCYEQIPTIRWQNKEKTIETEREH
                     KVYIDNRRLTKRTRLDFFDKFYSFAIVLVTSKRIEIQSYGFYSRYSNGRQSIEVKLCN
                     FEKLANNHHIKLTEQFGQYVPGLTPNFIGSGAYSGTKFYPDDWEEKIKSISELKYLQF
                     PIGLAHHNLPHMYKYRTQIEFLQKIDAWKIANDLAYDVTEYDAWHVRKAVDCRVITKK
                     WLHQNKQFFKNSNRSFREYELERRIKARNGKLVPGIEKILSYQDINKIPKAAKINRFQ
                     NWLVKNKVDFNYYIDYLSMLDELGIEIDTDNLIMPKDLVKAHDNVVKLVNQKKSEIEK
                     RKFKNRLKSLSKYEQTIGDYCFRAPVDSGELIREGKTLSHCVGSARYTQAHASGKTTI
                     IFIRRKSDSDKPFYTMEYKAGHIVQVRGKHNQSATEEVQKVVDQWLAIVNKNYKHA"
     gene            38202..38534
                     /locus_tag="VGY43_000331"
     CDS             38202..38534
                     /locus_tag="VGY43_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301552.1"
                     /translation="MITKINVPKTSIVIEIENKEITIENLINYDIKMIFRNQDNEPSL
                     DENGDIFEPMYWLDIKAKPNDEIEYHSSLGVKKEKRRLAELQIFFEYIEANKQNLFDL
                     CGLKGELA"
     gene            38531..39043
                     /locus_tag="VGY43_000332"
     CDS             38531..39043
                     /locus_tag="VGY43_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301553.1"
                     /translation="MSSLTLSLDVSTTGTGWAIFDGSTLIQSGASKPKQKSFYERAKS
                     MASELKTIQLRAIQKHDKPFEDIVIEQNTVLGPNQQSSIKIGIATGIILGRLLAEEIY
                     FVNVSTWRKYWKFSYKDRSKKSMKKQAINAVAAEFNKQVKDDEADAILIGSYFTNLGK
                     DFGDLESHKN"
     gene            39079..39396
                     /locus_tag="VGY43_000333"
     CDS             39079..39396
                     /locus_tag="VGY43_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEQ4301554.1"
                     /translation="MEIVKDGVKFIASMIIVLAATFGCGYLFYRAGYEQAKKEVQPVT
                     IYTVDNVGGVMVGEITDKEIIEGRYTVTAHAYGKFLVTKEQYKAIKVGDKIPDYLKKR
                     GTK"
     gene            39393..39548
                     /locus_tag="VGY43_000334"
     CDS             39393..39548
                     /locus_tag="VGY43_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301555.1"
                     /translation="MIELTQKQADYVEFVRKTIVDPDMMEFAVNTQLISYALLVGYCI
                     VDEEVAK"
     gene            39545..39796
                     /locus_tag="VGY43_000335"
     CDS             39545..39796
                     /locus_tag="VGY43_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301556.1"
                     /translation="MKPRKYPYSGKIRIIKKELPRFVRLGDFAFNSNLVKHIDKIRQV
                     KPNETLIRFKIPKLFMTYEEETFKVRLEIDKVVKILNQY"
     gene            39872..40291
                     /locus_tag="VGY43_000336"
     CDS             39872..40291
                     /locus_tag="VGY43_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEQ4301557.1"
                     /translation="MSKAKAILKDLRNLDLYIASLIRRQEKIETSLLSSPKWSSDKVN
                     GGIKRKQDDVYVELIATAEDIEKKTAEAIRKQRELQNLIDSLENTDSQTILSMVYIDK
                     MTRWQVIDELNCSESTYFRLLRVATKELNNLTVNDSD"
     gene            40399..40743
                     /locus_tag="VGY43_000337"
     CDS             40399..40743
                     /locus_tag="VGY43_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEQ4301558.1"
                     /translation="MSQLRADKKGTHRVAFEKNKRKLLKTTNLCGICGKPVDKTLKYP
                     HPLSAAIDHIVPIAKGGHPSALENLQLTHWQCNRQKSDKLFANQASNEPKTIGNRNLP
                     QSRDWSSFTLKK"
     gene            40891..41247
                     /locus_tag="VGY43_000338"
     CDS             40891..41247
                     /locus_tag="VGY43_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301559.1"
                     /translation="MKKKCLICKKNFQAKTNRTLYCSEECRKKGNREKQRKLMKQKRA
                     EQRKEKKKVLNPNTDVTEKPKKIRNLAQHYKKLKKEILANESEFGFTGITLIEGIDVH
                     EENFVDLVMQKIKEQK"
     gene            41244..42512
                     /locus_tag="VGY43_000339"
     CDS             41244..42512
                     /locus_tag="VGY43_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEQ4301560.1"
                     /translation="MNYMGMGYLRRKLALFKTGVDKRYRYYAMDDRDDTRSIVMPNNV
                     REMYRSVLEWTAKGVDSLADRIIFREFTNDDFNAWEIFKANNPDIFFDTAIQSALIAS
                     CCFVYIMPGAEDGLPKMQVIEASKATGILDPTTFLLTEGYAILESDSNGNPTLEAYFT
                     DKDIWYYPKKGKPYNIKNPTGHPLLVPIIHRPDAVRPFGRSRITKAGMYHQKAAKRTL
                     ERAEVTAEFYSFPQKYVLGMDPDAEPMEKWRATVSTLLEISKDEDGDKPTVGQFTTAS
                     MAPFMEHLKMYASLFAGGSGLTLDDLGFPSDNPSSVESIKAAHENLRAAGRKAQRSFS
                     SGFLNVAYIAVCLRDEFPYLRNQFMDTVIKWEPLFEADANMLTLVGDGAIKLNQAIPG
                     FMDADVIRDLTGVKGADKPIPAITEVTTDG"
     gene            42505..43998
                     /locus_tag="VGY43_000340"
     CDS             42505..43998
                     /locus_tag="VGY43_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301561.1"
                     /translation="MVDDVLPKLLKSVRQDFEKYFGESDVVTKAFAELQAKKVTYKTV
                     NEFAIEVGRLLSLALTGSVSSDKLPDGKMYYNIAKRLLDETMGRNYKLISGYAGDVQR
                     ILNENAQIGLKVQRPPLNRDKINGMVNRLDSENTFDDVKWLFGEPIVNFSQSIVDDTI
                     KANADLQYKTGMTPQVVRTESGNCCEWCREVVGTYSYPKVPKDVWRRHQRCRCTLDYD
                     PKNGKVQSAWSKIWRKKEKTQESIERVEKFKESALVESIKNDIAKLDMTKVGPSDIID
                     IGKRINYHFRVSEHIGDKEKLKEIFSNFREIGGEIPKNTWAKGSSKLVKDQLQEAFQN
                     YPTEWAAVPDGIGKKLKAIKRKRGYFDGYDEDLVIATNGTRKTTPYHEIGHMIELVNP
                     DLVRLEKAWVDKRTANEAEVRLKDIFPSSNYGIGEVTKKDDFISPYIGKYYSDAAEVF
                     TMGLQGIFVPEERFAKSFDKKTWKYDYKTINDDPEFLNFIIGLFVKV"
     gene            44004..44228
                     /locus_tag="VGY43_000341"
     CDS             44004..44228
                     /locus_tag="VGY43_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301562.1"
                     /translation="MEPKLHRQLRQKYDDAEKQYLEKFGEDSLDRVFFWEPDVYFDEW
                     KKVLPDATLELNKAINSGVAIDPDPENAIY"
     gene            44305..44457
                     /locus_tag="VGY43_000342"
     CDS             44305..44457
                     /locus_tag="VGY43_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301563.1"
                     /translation="MTWENKDEFQQIMNKVNETKEAYEKALEAAENFVPKMSCATKLN
                     KGEGNE"
     gene            44450..44716
                     /locus_tag="VGY43_000343"
     CDS             44450..44716
                     /locus_tag="VGY43_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301564.1"
                     /translation="MNKRIKKKRKLETAIMLLIAENALQAEAIKNQNKEIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK"
     gene            44718..44933
                     /locus_tag="VGY43_000344"
     CDS             44718..44933
                     /locus_tag="VGY43_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301565.1"
                     /translation="MKYRKKPVVVEAIQFTGTNYEKIKEFIGQNTLCSTLSIVIPTLE
                     GDYIIKGIAGEFYPCKPDVFEQTYEST"
     gene            45015..46430
                     /locus_tag="VGY43_000345"
     CDS             45015..46430
                     /locus_tag="VGY43_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEQ4301566.1"
                     /translation="MVTKTKTKLGNQRPTQSVNLHFAKSLAHEAINYYKKTGLSCYPW
                     QVNMLIPIMAIDENGLWVHQKYGYAIPRRNGKTEVVYIVELWALHKGLKILHTAHRIS
                     TSHASFEKVKKYLEMSGYVDGEDFISNKAKGQERIEFKASGAVIQFRTRTSNGGLGEG
                     FDLLIIDEAQEYTSEQESALKYTVTDSDNPMTIMCGTPPTMVSTGTVFEAYRKDCLKG
                     NKRYSGWAEWSVPEMVKINDVSSWYISNPSMGFHLNERKIEAELGEDEIDHNIQRLGY
                     WPSFNQKSVISEKEWAKLKVEQVPELKSKLFVGIKFGQDGNNVSLSIAARTSENKVFV
                     ETIDCLSVRNGTQWIINFLKSADIAKVVIDGASGQELLAQEMKEQGLKKPELPKVAEI
                     ITANMMWEQGIMQETICHSDQPSLTAVVTNCEKRQIGSNGGFGYKSLYDDRDISLMDS
                     ALLAHWICYTTKPKRKQRTSC"
     gene            46511..46972
                     /locus_tag="VGY43_000346"
     CDS             46511..46972
                     /locus_tag="VGY43_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ4301567.1"
                     /translation="MSEFKVIETQEELDTIVKARIAREREKYQDYDQLKTRVEELETE
                     NSSLQTALNDAKSNTDSYTEEISTLKNQIADYETANLRTKVALQYGLPIDLADRLQGD
                     DEDGLKVDAERLASFIKPSQPQPPAKSNEPNIDSNADANYRALVQGLSTED"
     gene            46997..47908
                     /locus_tag="VGY43_000347"
     CDS             46997..47908
                     /locus_tag="VGY43_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEQ4301568.1"
                     /translation="MGTETSKASLFDKHLVSDLINKVKGHSSLAKLSSQKPIPFNGSK
                     EFTFTLDSDIDVVAENGKKTHGGLSLEPVTIVPIKVEYGARLSDEFLYATEEEKIDIL
                     KAFNEGFAKKLARGIDLMAMHGINPRTKKASDVIGTNHFDSKVTQVVKFTESEDADAN
                     IEAAVNLIQGAEGVVTGLAMDTEFSTALAKVTNGEMGPKMYPELAWGANPDSINGLKS
                     SVNTTVGAGADEAESKDLVIIGDFESMFKWGYAKQIPMEIIKYGDPDNSGKDLKGYNQ
                     IYLRAEAYIGWGILDAKSFARVTKGEV"
     gene            47908..48108
                     /locus_tag="VGY43_000348"
     CDS             47908..48108
                     /locus_tag="VGY43_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301569.1"
                     /translation="MLYVNSKTGASFYSSVPVCGGDWTLVEQQTGEKAKTVAEIKRQL
                     DAAGIKYSSKAKKPELEALLPG"
     gene            48118..48540
                     /locus_tag="VGY43_000349"
     CDS             48118..48540
                     /locus_tag="VGY43_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage Gp19/Gp15/Gp42 family protein"
                     /protein_id="HEQ4301570.1"
                     /translation="MGNFATTDDVILLWRPLSVDELKRANALLKVVSDTLRMEADKVG
                     KDLDKTMVDKPYFVNVIKSVTVDIVARTLMTSTQGEPMSQESQSALGYTWSGTYLVPG
                     GGLFIKDNELKRLGLKKQRYGGIELYGEIKRDNDYFDR"
     gene            48500..48838
                     /locus_tag="VGY43_000350"
     CDS             48500..48838
                     /locus_tag="VGY43_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301571.1"
                     /translation="MGKLRGITITLIDKVTIDIDPFGNPIKKDKEISVDNVLVSPATS
                     DDITSQLSLSGKKAVYTLAIPKGDNHDWGDKEVRFFGEKWRTVGLALEGIEELIPLEW
                     NKKVMVERYE"
     gene            48831..49067
                     /locus_tag="VGY43_000351"
     CDS             48831..49067
                     /locus_tag="VGY43_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301572.1"
                     /translation="MSKFKFKLNKAGVAELMKSSEMQQVLTTKATAIRERCGDGYAQD
                     IHVGKNRANAMVSAKTIKAKKDNSKNNTLLKAVR"
     gene            49068..49403
                     /locus_tag="VGY43_000352"
     CDS             49068..49403
                     /locus_tag="VGY43_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301573.1"
                     /translation="MIEVIIKKYLDEHLDVPSFFEHQKDEPARFIILEKTSGAKQNHL
                     LSSTFAFQSYAESLYEAALLNDKVKQVIEQLDVLPQVSGVHLNADYNFTDTATKRYRY
                     QAVFDINHY"
     gene            49419..50009
                     /locus_tag="VGY43_000353"
     CDS             49419..50009
                     /locus_tag="VGY43_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ4301574.1"
                     /translation="MANDTKNVTSAKPKAGGAIYSAPLGTTLPEDAKSKLDTKFKNLG
                     YVSEDGVVNEDTRSSENIKAWGGDIVGSVQTEKEDKFTYKLIESLNVEVLKEVYGAAN
                     VTGDLDKGIHIKSNSKELEAHAIVIDMIMNGGILKRIVLPNAKVDEVGEIKYVDGEVV
                     GYETTLKCFPDEKGDTHHEYIVKPGEANKKENSFEM"
     gene            50020..50283
                     /locus_tag="VGY43_000354"
     CDS             50020..50283
                     /locus_tag="VGY43_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301575.1"
                     /translation="MEILKGKTTSGFEYEIPKKRLKNFELVEAIAEEETDPTAVVKIV
                     NLLLGDAAKSLKEHVRDAEGIVDVEAIGVEIKEIFESQKDLKN"
     gene            50298..50669
                     /locus_tag="VGY43_000355"
     CDS             50298..50669
                     /locus_tag="VGY43_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5361 domain-containing protein"
                     /protein_id="HEQ4301576.1"
                     /translation="MIAKDDDALTCDLAETYGIYDYRQLPAYQVAVFAVGLRSNSRIK
                     MALSGETEALDTVLLAGIYDNTNLLFWSKTKDGQSGQNKPKSVVEAISGSKSQKANDV
                     ISFASGEDFENARKQLLGGDG"
     gene            50669..53032
                     /locus_tag="VGY43_000356"
     CDS             50669..53032
                     /locus_tag="VGY43_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301577.1"
                     /translation="MATELGQAYVQIMPSARGISGAISKQLDPEARSAGLSAGKLFGS
                     KLKLAALAATAGLGILLKKTISASLSTGADLQQSFGGIDTLYKGAETAVKGFAKEAYK
                     AGISANTYAEQAVSMGASLKQSLGGDAVAAAKAANMAIMDMADNSAKMGTDITSIQMA
                     YQGFAKQNYTMLDNLRLGYGGTKEEMKRLLSDAEKLPAAMGKKFDLSNYADVVEAIHL
                     VQDNMGIAGVAAEEAKTTFSGSLAAMKSSFTNVLAGLSLGDDIRPALRGLAETTSNFL
                     FGNFIPMVANIFKGLPSAIGTFIGAATPIIASQFKGLMSSLGISIDLSPITAKFAQIG
                     QNLQPVFNGLKTAFSQLPSFFTSIGSAVAPVIDTIISGLARLDFSGFEALISAILPAI
                     QTGFQTFMSIVGPAISQLVNSFVNLWNACQPLVTILSGALMPAFQILGAFLGGVLQGI
                     LGSISFAFDALKVVIEFLTPIIDWLVQGFNAISPALQIVAQWVGNVIGIFTSLGASGQ
                     GLSSMLSSAWGNIQTVVSTAKNMITLAIDGIKLVFSNLGNAGNILKGLLSAAWSAMQN
                     AVVIAKGIINSAISAIKTAFSSFGNLVSSVSGTIKSVIGSLKNAFYSLASIDLVGAGR
                     AIMQGFLNGLKSMWGAITGFVGGIADWIRKHKGPISYDRVLLKPAGKVIMQGFNNSLM
                     DGFKEVKSNVSGMADDLAGTITGKSLSLGIDAKPSVTADDLLSSNISTKTTVGSATSD
                     LSLFFVKVLALLQDILDKNTDVYLDKEKVSAILYEEFAKIMAREGIA"
     gene            53029..53724
                     /locus_tag="VGY43_000357"
     CDS             53029..53724
                     /locus_tag="VGY43_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301578.1"
                     /translation="MIPKVIIDGFDTSTIPNCVLTGYDVGDVLSPHFVENEVYGMNGT
                     SRGLESYNESKPTLTWHLSTFDDAVNLVNHLDGLGKIIEFWHIPKSFYYYDCLSVKIN
                     AVTMNSWRVTLKLALYPFRYAKGISDVTIAGNGSINNPGNVFSEPKIIVEGTGKGTLT
                     IDKQVMELNLSGKATIECKHGQQCVYDGEGNVKNSIRIRGRFFEIQPGTQGIAVSGGI
                     ARLTISPRWRYKV"
     gene            53706..55679
                     /locus_tag="VGY43_000358"
     CDS             53706..55679
                     /locus_tag="VGY43_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ4301579.1"
                     /translation="MEVQGLISIKDDNTPLVAAFEDEITQEANSDYKLSFKYPAKHEY
                     RPLIKKGIILEADDLHGTQLFRVFEITKRHGYINVYGNQVADDLNGYAIDSISVDRVQ
                     GMTVMSELAGNIKREHPFSFFSDIDGRHTFNQSDVSVMDALANGKHSIMGQWGGELVR
                     DKYQVNLLKKAGKDTETLFMYKKNLKSYEETDTIKGLISILHLVAEVEEQREEESREV
                     SDADIGHNEVSKKKTIRVTVESKLKDTHPIIVEKTIKVQDQDVKTEEDLLAYGKKYFE
                     KTLCDIPGNSLKIDVTNNYEGAVRLFDTAIVFHELYDRDLRMQITGYRFAPMANRLKS
                     IIFGEIKTNLAKQISNQIDNKVAESTAQHDAAFEAKLQKQIDNANRIFDTKEAKLREE
                     IEDGIKKAEANAEVKVAEVNAKVLEAEELAKAVDERLKKFLSDADTKEQDFDKKLEEF
                     RTSLKDLEVDEKQIDDALAKAGFSKDSLADIKAKLEDTSETATVTANIVGSTGGTFYN
                     RNRLDGDTDKVITFEQGYIDIAHNGEGFEEGKTYTISFEATCELLRKVGITVTQANMK
                     GARLVLTPKNPKLVVESFGLTKDTETINVYPFSYTVLVTSDWYKSKQIDLNASEVQEL
                     ALEMAYKDVVDGNNATIAGQWSDSPQMILDGGS"
     gene            55679..56788
                     /locus_tag="VGY43_000359"
     CDS             55679..56788
                     /locus_tag="VGY43_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_115223326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEQ4301580.1"
                     /translation="MTENIPLRVQFKRMSADEWARSDVILLEGEIGFETDTGYAKFGN
                     GKSKFSALKYLTGPKGPKGDTGFQGKTGGTGPRGPAGKPGTTDYNQLQNKPNLDAFAR
                     KQETDSKITELKSNKADKNAVYLKAESNAKLDEKLSLTGGIVTGQLQFKPNSGIKPSS
                     SVGGAINIDMSKSEGAAMVMYTNKDTTDGPLMILRSDKDTFDQSAQFVDYSGKTNAVN
                     IVMRQPSAPNFSSALNITSANEGGSAMQIRGVEKALGTLKITHENPNVKANYDENAAA
                     LSIDIVKKTNGEGTAAQGIYINSSTGTTGKMLRIRNKNEDKFYVGPDGGFHSGANSTV
                     AGNLTVKDPTSGKHAATKDYVDEKIAELKKLILKK"
     gene            56803..>58319
                     /locus_tag="VGY43_000360"
     CDS             56803..>58319
                     /locus_tag="VGY43_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301581.1"
                     /translation="MSRDPTYTINEHDLSFADGRFYVTFKADKSSETVRLNSSCLGNT
                     IIKKLQVEDDNTMHDFVKPKVTTQQAFGLAQQVKELDLQLKDPKSDLWGKIKFNNKAM
                     LVEYANKEMSSAIAQSAEQILLQVKSIDDERYSKFEQTLNGIKQTVKSESVESARTQL
                     ASMFDSRISGLDGKYSRLSQTIDSLSSRLDDGVGNYSTLSQKVSGIDLRVSNAANDVS
                     RLSQTAQGLQSQITNANQNYSSLSQTVQGLQTTVRDNQSNATSRINQLSDLISTKVSK
                     GDVETTIAQSYDKIAFAIRDKLPASKMSGSEIISAINLDRSGVKITGKNITLDGNSYI
                     SNAVIKDAHIANMDAGKINTGYLNANRIATEAITGEKIKMDYAFFNKLTANEGYFRTL
                     FAKDIFATSVQSVTLSASKITGGVLAATNGASQWDLNNANMTFNRDATINFNSKNNAL
                     VRKDGTHTAFVHFSNATPKGYRGSALYASIGITSSGDGIDSASSGRFCGVRFFRYA"
BASE COUNT        19220 a         9795 c        12420 g        16884 t
ORIGIN      
        1 tgttttttag cagtttttag aatagcaaaa gtttggaaag taagtgaggt caagtgaatg
       61 gctagaaatg gcttttttac tggtttggac attggaacaa gctcgataaa agttttagta
      121 gcagaattta tttctggtga gatgaacgtc attggtgtta gtaatgttcc aagtaccggc
      181 gtaaaagatg gcataataat cgatatagag gcagctgcga ctgccatcaa aactgcggta
      241 gaacaagcag aagaaaaagc agggatgaca attgaaaagg ttaatgttgg gctaccggca
      301 aaccttcttc aaattgaacc aacacaagga atgattcctg tcccaagtga gtctaaagag
      361 ataaaagatg aggatgttga tagcgttgtt aaatcggctt taacaaaaag tatcacacca
      421 gaacgagagg ttatctcttt agttccagaa gagttcattg tggatggctt tcagggcatt
      481 cgagatccac gtggtatgat ggggattaga ttagagatgc gcgggcttat ttatactgga
      541 ccaagcacca ttttacataa tctgcgtaaa acggtagaaa gagcaggcat taaagttgaa
      601 aacatcatta tttctccgtt agctatggct aaaaccattt taaacgaagg tgagcgcgag
      661 tttggagcta ctgtaattga tatgggaggt ggacagacaa ctgtcgcttc tatgcgagca
      721 caagaattgc agtataccaa tatatatgct gaaggcggcg aatacattac taaagatata
      781 tcaaaagtat taaaaacgtc tttggctatt gcagaagcac ttaagtttaa ttttggtcaa
      841 gcggagatat cagaagctag tataactgaa acagtaaaag ttgatgtggt aggtagtgaa
      901 gagcctgttg aggtaactga acgttattta tctgaaatta tttcagcgcg tattcgtcat
      961 attttagatc gtgtgaagca agatttggaa agaggtcgtt tactagactt accaggaggc
     1021 attgttttga ttggcggcgg tgcaatcatg cctggagtgg tagagattgc acaagaaatc
     1081 tttggagtaa ctgtaaagct ccatgttcca aatcaagtcg gtattagaaa tccaatgttt
     1141 tcaaacgtta tcagtttggt agaatatgtt ggtatgatgt ctgaagtaga cgttttagca
     1201 caaactgcag tttcaggaga agaacttttg cgacgcaagc ctatcgattt cagtggtcaa
     1261 gaatcttatt taccagatta tgatgattca agaagaccag aatcgaccat tggctatgaa
     1321 caacaagcgt cacaaacagc atatgattca caagttccga gtgatcctaa acaaaaaatt
     1381 tcagaacgtg ttcgtggcat atttgggagt atgtttgatt aaaagtaata aagtgaggag
     1441 ataaaatggc attttcattt gatactgcat caattcaagg tgcaattata aaagtaattg
     1501 gagtcggcgg aggtggcgga aatgccatta atcgtatgat tgatgaaggt gttgctggtg
     1561 tcgagttcat cgcagcaaac acagacattc aggcattaag ctcatcaaaa gctgaaacgg
     1621 ttattcaact aggccctaaa ttaactcgtg gacttggtgc tggaggacaa cctgaagtag
     1681 gacgtaaagc tgctgaagaa agcgaagaaa ttttaacaga agctcttaca ggagcggaca
     1741 tggtatttat tactgccggt atgggtggtg gctctgggac aggggctgca ccggttattg
     1801 ctcgtatcgc taaaagtttg ggagccttga cagtagctgt tgttactcgc ccgtttggtt
     1861 ttgaaggtaa caaacgtggt aattttgcta ttgaaggtat cgaagaactc cgtgaacaag
     1921 ttgatacttt gttaattatt tcaaataata accttcttga gattgttgat aaaaagacac
     1981 ctttattaga agcacttagt gaagctgata atgttttacg tcagggagtt caagggataa
     2041 ccgacttaat tactagtcct ggccttatca atctcgattt tgccgacgtg aaaacagtta
     2101 tggcaaataa agggaatgcc ttgatgggga ttgggattgg ttctggagaa gagcgcattg
     2161 ttgaggcggc gcgtaaggca atctattcac ccctattaga aacgactatt gatggtgcac
     2221 aagacgttat tgtgaacgtt acaggaggtc tcgacatgac actcacagaa gctgaagaag
     2281 cctctgaaat tgttgggcaa gctgctggtc aaggcgttaa catttggtta ggaacatcta
     2341 ttgatgatac tatgaaagat gacatccgtg tgactgttgt agcaactgga gtgcgccaag
     2401 aaaaagccga acaagtttca ggttttcgtc agcctaggac ttttacccaa accagcgcgc
     2461 agcaagtagc gggtgcacaa tatgcatcag atcaagcaaa acagtcggtt caaccagggt
     2521 ttgatcgtcg ctcaaatttt gattttgaca tgggggagtc tcgcgagata ccaagtgcac
     2581 aaaaggtaat ttctaatcat aatcaaaatc aaggttcagc ttttggaaat tgggatttga
     2641 gacgtgataa tatttctcgt ccaacagaag gtgaattgga taaccatctt aatatgtcaa
     2701 cgttctcagc taacgatgac agtgatgatg aattagaaac gcctccattc tttaaaaacc
     2761 gttaataatg gatttactga caaataaaaa gaaaattttt gagactatcc gcttatctac
     2821 agaggcagca aataggacta atgatagtgt ttcagttatt gctgtaacaa aatatgtgga
     2881 tagtacaatt gcaggtcagc ttatcgaagc aggaattgag cacattgccg aaaaccgtgt
     2941 tgataaattt cttgaaaagt atgatgcgtt aaagtatatg ccagtaaagt ggcatttaat
     3001 tggtacctta caacgtcgta aagtcaagga agttatcaat tatgtcgatt attttcacgc
     3061 tctagattct gtgagattag ctttggaaat caacaagaga gctgaccatc ctgtgaagtg
     3121 ttttctacaa gttaatattt ctaaagaaga gagtaaacat ggttttaaca tttctgagat
     3181 tgatgaagcg attgaagaaa taggtaagat ggagaagata cagttagttg gtttaatgac
     3241 tatggcacca gcaaatgcca gtaaaggaag tattataact atttttcgac aagcaaatca
     3301 attaagaaaa aacttgcagt taaaaaaaag aaagaatatg ccttttacag aattgagcat
     3361 gggcatgagt aacgattatc caattgctat tcaagaaggc tcaactttta ttcggattgg
     3421 tagagctttc tttcactaat ggagaataag atggctttta aagatacatt taacaagatg
     3481 atttcttatt ttgacacgga tgaggttaac gaagttgaag aagatgttgc agcatcaact
     3541 gataacgtta ttccaagatc acaacaatca gtcagagcaa gtagtcatcc aaaacaagaa
     3601 cctagaaaca atcacgtaca acaagatcat caagcgagat cccaagaaca gacaaggtca
     3661 caaatgcatc caaaacatgg tacttctgaa cgctattatc agcagtctca gccaaaagaa
     3721 ggccatgaaa tggttgacag aagaaaacgg atgaacactt ctggtattgc aaatcgccgt
     3781 gagcagtatc aacaatcaac ttgttcagat caaacaacta ttgccttaaa gtatcctcgt
     3841 aaatatgagg acgctcaaga aattgtggat cttttaatag ttaatgaatg cgttttgatt
     3901 gattttcagt ttatgctaga tgctcaggct agacggtgtt tagattttat tgatggtgct
     3961 agtaaagtgc tctatggtag cttacaaaag gtcggctctt caatgtactt actggctccg
     4021 tcaaatgtat ccgtcaatat agaagaaatg actatcccac atactacaca agatattggc
     4081 tttgattttg atatgaaaag gcggtaaata aatgatatta atactatcta ttcttcttcg
     4141 tctgatcaaa gtttacactt atttattgat tgcttacgca ctaatgtcat ggtttcctgg
     4201 ggcatacgat tcaaaaattg ggcgtttgat tagtggtatc gttgaaccaa ttttaaaacc
     4261 ttttagagca tttaatttac aatttgccgg tcttgacttc actatttttg tcgtcattat
     4321 tagtttgaat tttttagctc aagttttggt ccgtgtgttt atttaatggt tagtcatagt
     4381 aagatttatc agcattttca ccaagaagaa tatcctttta ttgatagaat gtctgatatg
     4441 attaatagag ttgaagatta ctatctttta gaagttactg agtttttaaa tcctagagaa
     4501 gtgatgattt taaaaagttt gattgcttta acagatctaa aaatgttcgt atcaacagat
     4561 tactacccaa gcgaatatgg tcgtgtcatt attgcacctg gttactatga cttagaacaa
     4621 agtgattttc aaatagcttt agtagagata agttatcagg caaagtttaa tcagttgaca
     4681 catagtcaaa ttttaggaac tttaattaat gaattaggag taaagcgaaa tttatttgga
     4741 gatgtttttg ttgaaatggg atatgcccag ctcatgatta agcgggagtt attggattat
     4801 tttttaggaa caattactaa aatagctaaa actagtgtga aattaagaga agttaacttt
     4861 gatcagttaa ttaggtctat tgataacagc cagaccctgg atattctagt ttctagtttt
     4921 cgattagatg gtgtagttgc tactatctta aaaaaatctc gaacgcaagt tatagcatta
     4981 attgaagcaa ataagattaa ggtaaactat cgactcgcta ataaagcttc agataatcta
     5041 gtcatagggg atatggtgag tatcagaggt cacgggcgtt ttactctttt agcagataat
     5101 ggagtgacca aacatggcaa acaaaaaata acactaagta aaatgataca taaataagga
     5161 gatacaatgg cacttacaac gctagaaatt aaagataaaa cttttaagac aaaattccga
     5221 ggatactgtg aagaagaagt caatgaattc cttgatattg ttgttgatga ttacgaagct
     5281 cttgtacgta aaaatcgtga taacgaagca agaattaaag atcttgaaga aaaattatct
     5341 tactttgatg aaatgaaaga gtcacttagc cagtctgtaa tcttagctca agaaacagct
     5401 gaaaaagtga aagctacggc taatgcggaa gcaacaaact tggttagtaa agcgacttat
     5461 gatgctcagc atttattaga tgaatctaaa gctaaagcca atcaaatgtt gcgtgatgca
     5521 actgatgagg ctaagcgagt tgcgattgaa acagaagaat taaagcgtca aacacgtgtg
     5581 ttccaccaac gtttaatctc atctattgag tcacaattaa gcttatcaaa ttcacctgaa
     5641 tgggatgaac tgctacaacc gactgcaatc tatcttcaaa attctgacga tgcttttaag
     5701 gaagtcgtga agaccgttct taatgaagac attcctgaat ctgatgatag tgcctctttt
     5761 gatgcaacac gtcagtttac tccagaagag ttagaagaat tgcaacgtcg tgttgatgaa
     5821 agcaataagg agttagaggc ttaccaactt gactctcaat ctgattctac gactgagcca
     5881 gaggtaaatc tcagtgaaac acaaacgttt aaattaaata tctaaataaa gaaaaacaag
     5941 atgatttgct tataatcaca gcaagcggga gatgatgaga gtctcgtatt ccctaagtat
     6001 tatcattatc attttctaaa attttcgctg aactacagta agcgaggagg tttgttcacc
     6061 ttacgagcaa agagggagcg gtaagtctta tgatatatta tcgctctgaa ctaaggtggt
     6121 accacgagct ttcgtccttt ttgagacgag gcttttttcg ttatagtcgc aagtttgttt
     6181 aaaaggagtt tgaaataatg aaattaaaag agacacttaa tctaggaaaa actgcctttc
     6241 caatgcgtgc aggtcttcct aataaagagc cacaatggca agcagcttgg gaacaagcag
     6301 agctttacaa aaaacgtcaa gaattgaatg caggtaagcc tgcctttcat cttcatgatg
     6361 gacctcctta cgctaacggc aatattcacg ttgggcatgc ccttaataaa atttcaaaag
     6421 atatcattgt gcgttctaag tccatgtctg gctttcaagc gccttatgta ccaggttggg
     6481 acacacacgg ccttccaatc gaacaagtct tggctaagca aggaatcaaa cgtaaggaga
     6541 tggatttagc agaatacctt gagatgtgtc gtcaatacgc tttaagtcag gttgataaac
     6601 agcgaaatga tttcaaacgg ttaggtgttt cggcagactg ggaaaatcct tatgtcactt
     6661 tggacccaca gtttgaagct gatcaaattc gtgtttttgg agcgatggct gaaaaaggtt
     6721 acatctatcg tggtgctaaa cctgtttatt ggtcatggtc ttcagaatcg gccttggcag
     6781 aagctgaaat tgaataccat gacatcgatt caacctcttt atactacgcc aataaagtta
     6841 aagatggtaa aggcatcctt gatactaata cgtatatcgt tgtttggacc acaacaccat
     6901 ttaccgttac agcatcacgc ggtttgactg ttggtcctga tatggattat cttgtggtga
     6961 aacctgctgg ttcagaccgt caatatgttg tggcagaagg tcttttgaat agccttgctg
     7021 gaaaatttgg ctgggaatct tttgaaactt tagccagcca taaaggagct gatttagagt
     7081 acattgtgac agaacaccca tgggatactg acgtagaaga attggttatc cttggtgacc
     7141 atgttaccct tgagtcaggg acagggattg tccacacggc gccaggtttt ggtgaggatg
     7201 actacaatgt tgggacaaaa tacaaactgg aagttgctgt gactgttgat gaacgtggcc
     7261 taatgatgga aaatgcaggt ccagatttcc acggacaatt ttataacaag gtaacgccga
     7321 ttgtcattga taaacttggt gatcttttat tggcacaaga agtgatcaat cactcttacc
     7381 catttgactg gcggacgaaa aaaccaatca tctggcgtgc tgtaccgcaa tggtttgctt
     7441 ctgtttctga tttccgtcaa gatattttgg atgaaattga aaaaacaacc ttccatccat
     7501 catggggtga aacacgcctt tacaatatga ttcgtgatcg tggcgactgg gttatttctc
     7561 gtcaacgtgc ttggggagtt ccgcttccta tcttctatgc cgaagatggc acagctatta
     7621 tgactaaaga agtgacagat catgtggctg atttgttcca agaaaatgga tcaatcattt
     7681 ggtggcaaaa agaagctaaa gacctattac cagagggctt cactcatcca gggtcaccaa
     7741 atggcgagtt tacaaaagaa actgatatca tggacgtttg gtttgactct ggttcttctt
     7801 ggaatggagt catgaatgct agagaaaatc tttcctatcc agcggatctc tacttagaag
     7861 gctctgacca gtatcgtggt tggttcaatt catccttaat tacatctgtg gctgttaatg
     7921 ggcatgctcc atataaggct attttatcgc aaggctttgt tcttgatggt aagggcgaaa
     7981 aaatgtctaa atcaaaaggc aatatcattt ctcctaatga tgtggctaaa caatatggtg
     8041 cagatattct tcgactttgg gtagcttctg tggataccga caatgatgtc cgtgtttcta
     8101 tggagatcct tggtcaagtc tctgaaacct accgtaaaat ccgtaacacc cttcgtttct
     8161 tgattgctaa tacatctgat ttcaaccctg ctacggatac agtagcttat gcagacttag
     8221 gagctgttga taagtacatg acaattgtct ttaatcagtt ggtagcaacg attactgacg
     8281 cttatgagcg ttatgacttt atggctattt acaaagcagt ggtgaacttt gttacggttg
     8341 atttatcagc cttctatctt gattttgcta aagacgttgt ctatattgaa gctgccaata
     8401 gcttagaacg tcgtcgcatg cagacagtct tctatgatat cttggttaag attaccaagt
     8461 tattgacgcc aatcttgcct cacaccactg aagaaatctg gtcttatcta gaacatgagt
     8521 cagaagcatt tgttcaattg gcagaaatgc ctgtggcaga aactttctca gctcaagagg
     8581 atattttaga agcttggtct gctttcatga ctttgcgtac ccaagctcaa aaagctttgg
     8641 aagaagcgcg aaatgctaag attatcggta aatcattgga agcccatttg accatctacg
     8701 ctagcgaaga agtgaaaacc ttattgactg ctttagacag cgatattgct ttgcttttga
     8761 tcgtgtctca attaaccatt gctgacttgg cagatgcgcc tgcggatgca gtggcatttg
     8821 aaggtgttgc ctttatggta gaacatgcca taggtgaagt ttgtgagcgt tcacgtcgca
     8881 tcgacccaac tactcgcatg cgttcttaca atgcatttgt ctgtgatcac agcgctaaaa
     8941 tcattgaaga aaatttccca gaagctgtgg ctgaagggtt tgaagagagt ggcaaataag
     9001 tcttatcaag acttgaagtg acactgagta agaagacaac catcgggtct taggacctga
     9061 tggtttttta gtagagctga ttacgtccat tagccagctt taacgagaga caaagtagga
     9121 gaaatttaga ctactttttt aatttctttt aagaaaattg ctggcttcat ataaggacta
     9181 ttaagataga gttcaccttt cgctaataaa aaaacttagc tcttttagaa gggctaagtt
     9241 ttgtctgaat agctggctgt tgtttataca gaagtttgaa atgaaatttc aataaggtta
     9301 ttcgtgtgaa gtgtttttga ttgtccagga ataacaattt taggatcaat tttacgtttt
     9361 aaaaaaaatt cgcgaatgat atcaagttca tcctccttga gggcacggta tttatttgaa
     9421 ataagtagtt cgtaatgttt tggtgcttgg gtaaaaatga catctgtatt ccctgctgag
     9481 tatacttcga ctaaataggc atcggtgttt tttagctgat ttctgatgag ttctgggtga
     9541 ctgctagtgg tattgatgag tctcataaat gtcctcctta gtattcctgt acctattata
     9601 gcactaattt aaagccttag ttagtagaat gatgcttttt ttgccattcc ttgactcccc
     9661 attgatggct ctctcgtttt aatttagcaa ttgcctcgat aggagaaaac caacctaagt
     9721 tattaaaatc ttctaagggc ttagaaacgg cttgaaatgc agttacttca taaagatagg
     9781 caggatggta gaagtgggta tcacgatggc gagagtagaa atattcatca gcctgaccgt
     9841 aatatgaacc aatagtagca gaaaaaccaa gttcttcaat cagttcacgc tctagggcct
     9901 gaagctgacc ttcacctgct tcaatttcac caccaggtaa aaaccaggaa ccattaggag
     9961 cttgaacaag aataattttt gtttgttcgt gattgggaat gatagcatag acaccgtaac
    10021 gtgtgacata gtctttatgt gcatttttat gtccaaatgt tggaatcatc attttattta
    10081 cctttccttt ttcttcatta tactaaattt ttgctaatta ttcttatcaa tttgtttagt
    10141 ttaataaaaa attgatagaa aaagagagag tctccttata gaaactctct tagctaacgt
    10201 taatcgagag actcttcgtt aagaaaagaa tctccctctt taacagcttt aatcgtgata
    10261 ttttcactgt ttgtcatcag tgcacgtaac tgtttttcag ttgggtgctc taaataatag
    10321 tctgtaatgg catcttctat ataatcttgg atagtacgac ggagcggccg agcgcccatt
    10381 ttaggatcat agcctaaatc tactaatttt tctttgacct tttgtgtcac atcaagatga
    10441 atcccattat agcctaagcg ctcattaaca tcttccagca ttaaatcaac gatatgcagc
    10501 aaatgctctt tagataaagc tttgaattca ataataccat cgaaacgatt cataaactct
    10561 gggctgaaga agttgcttaa ttcaccaagg acagaacttg tccgtccttc tctagcagca
    10621 ccaaatccga cagaagcttc gcttttacct gttccggcat tagaggtcat gataataatg
    10681 gtgtccttga agctgactgt tcgtccttgg ccgtctgtta agcgaccgtc atcaagaact
    10741 tgtaagaaca tgtgcatgac gtcaggatgg gctttttcca cctcatctaa gagaataagt
    10801 gaatatggat tgcgacgaac ttgttcggtt agctgtccag cttcttcata gccgacataa
    10861 cctggaggag ccccgactaa tttggcgaca gcgtgttttt ccatgtattc ggacatgtca
    10921 aagcgaatca tattgtttgt cgaaccaaag agttcaatgg ctagttgttt agacaattca
    10981 gttttaccaa ccccagtcgg tccaacgaat aagaaagaac caatagggcg atttggagtt
    11041 cctaatccca cacggttacg acgaatagcc ttagcgattt tatcaacagc atcgtcttgc
    11101 ccgatcacgt gtgctttcag atcattggct aagtttacga gttgagactg ttccttttct
    11161 tttaagtccc caactggaat attagttttt tgctctacaa tagcttcaat ggttttttca
    11221 gtaatgatgg gaatatcttg ctcatcgact ttttgagcct gcatttcttt gtattttgta
    11281 atttgatcgc ggaaataagc tgcgcgttca tagtcttcgt ctcgagtagc ttgcgccttg
    11341 agattctcag cttcaataag acgtttgtca atttctttag gatcaacaaa gttgagggtt
    11401 agattcattt tggaaccagc ttcgtccaga agatcaatag ccttatcagg aagaaaacgg
    11461 tcttgaatat agcggttaga taaatgagcg gcagcttcaa tagcggctgg gctatatttg
    11521 acatgatgat agtcttcgta tttcggttgg atacctttta aaatcgtgat ggtttcctca
    11581 acagaaggtt catcaacttt aacgggttgc atacgtcgtt ctaaggcagc gtctttttca
    11641 ataatacggt attcatttaa tgtagtagca ccaacgagtt gcaactcacc acgggccaag
    11701 gctggtttta aaatattacc agcatccata ttgccgtctc ctgcagaacc agcaccgaca
    11761 atctcatgaa tttcatcaat aaagagaatc acatccttgc gattgcgaat ttcttccatt
    11821 aatttttgca tgcgctcttc aaactgacca cggatacctg ttccctgaac gaggctaacc
    11881 acatcaagac gaatcacttg cttgccttgg agtttttgag gaacagtacc atcaataatt
    11941 ttttgagcca aaccttctac aacagcagtt ttaccaactc caggctcacc aattagcaca
    12001 ggattatttt tagtacggcg gttgaggatc tcgataacgc gtgtaatctc ttcgtcacga
    12061 ccaataacag gatcaatatt accatttctt gcaatatctg tgacattaat cccaaactct
    12121 tctaacaagc cctttgcttg ctgatttgat gtttgtggct gagcaggtcg ttgtccgttg
    12181 tagttaccac catagcgtcc tccgccattt ccattttgcc ctgcctgagt aggtggggta
    12241 tttggaagat taccaaaagc tctaaaatta ttcaaatcac caaaaaagtc atcaaagaaa
    12301 ggacttgtgg atctatcttg tgctctatat cctggggtta ggccatttaa aatagaattg
    12361 gcaggatcgg atttcatgat ttgataacaa ttttgacaga gatcaacctg tctttgtttt
    12421 ccattaacac ttgtataaag atgaatagta gattcgttta aattacaatt ttgacacagc
    12481 ataatatacc tccgagggtt tatctaaaag tcaaagtcat ttagtcaaaa atggtcaaac
    12541 tttatattca tattatagca ccacggcttg ggaaatcaag taaaaagttt atcgctttag
    12601 cgttagcttt tagagagtaa catgacagag taactttatt aagtttccaa tgagcaaatg
    12661 tttaaaatca ttgaaaagag taaaaaaagt aaaatatcaa taaatatatt actttccttg
    12721 ttagtttccc ttgttttgtg ttaaaataag agggataaaa aacgaatagg agaaacgaaa
    12781 tggaatcaca tttggtgaga atcatcaatc gtttggagtt gatggtgaca gatggcggta
    12841 atctcaagcg aaattttgaa cgcgatggtg ttgttgttgc agaagttgcc ttttcaaatg
    12901 atcctgaaaa tggacctgtt ttcacattgc gtgatgttga agcgcgtgag tcatattcct
    12961 ttgatagcat tgacttgatt gcaatggaaa tctacgattt attatattaa gcttgacata
    13021 gtaaagagac ttgcctgagg caggtttttt tattgtcaaa aagtattgta ttaatattca
    13081 tcagatggta taattatctt tattgtaatg aacctaggac ttatgaggag atataaatgg
    13141 atttgtcatt tttgcccaaa tactgggcct actttaacta cggtgtactt gtcaccatta
    13201 tgatttcagt cagcgttgtc ttttttggaa cccttattgg tgtcttggta accctgatta
    13261 agcgtagtca tgtgaagccg ttgacctggg tcgttaatct ttacgtttgg atctttcggg
    13321 gaacacctat ggtggttcaa atcatgattg cctttgcttg gatgcatttt aacaatatgc
    13381 ctactattgg ttttggggtt ttagacttgg acttttcaag actacttcct ggaattatta
    13441 tcatttcatt gaatagcggt gcttatattt cagaaattgt tagagcaggt attgaggctg
    13501 taccaaaagg gcaattagaa gcagcttatt cactaggtat tcgtcctcaa aatgccatgc
    13561 gttatgtgat tttgcctcag gcctttaaaa atattttgcc agccttagga aatgaattta
    13621 ttaccattat taaggatagt gctcttttac aaaccattgg agtgatggaa ctttggaatg
    13681 gtgcccaatc ggtggtaacg gctacttatt ctccaatttc ccctttactg gtggctgctt
    13741 tttactactt aatggtcaca acagtgatgg cacagttatt ggcagtctta gaacgtcaca
    13801 tgtcgcaagg aggtaatcat tgatgactga ggctattatt tcaattaaag acttgcacaa
    13861 gtattatggg cacaatgaag tgcttaaggg aattgattta gacattatgc caggagaggt
    13921 tgtggtgatt attggccctt ctggttctgg aaaatcgacc ttacttcgaa ctatgaatct
    13981 tttggaagta ccaactaagg gacagattag gtttgagggg attgatatta ccgataagaa
    14041 gaatgatatt ttcagcatgc gtgaaaaaat gggaatggtt ttccagcagt ttaacctctt
    14101 tcccaatatg actattttag aaaatatcac tttatcgcca atcaaaacta agggaatggc
    14161 taaagcagag gctgacaaaa cagccttgag cttgttggac aaagttggat tatcagaaaa
    14221 agccaaggct tatcctgcta gtctttctgg tgggcaacag cagcggattg cgattgcgcg
    14281 tggactggct atggatccag atgttttact ctttgatgaa ccaacttcag ctctagaccc
    14341 agaaatggtg ggtgaggtct tggctgtcat gcaagatttg gctaaatctg ggatgactat
    14401 ggttattgtg actcatgaaa tgggctttgc taaagaagtc gcagatcgtg tgatttttat
    14461 ggatggcggc gttattgtgg aagaaggaag tcctaaccaa ctttttgatc tgactaaaga
    14521 agaacgtaca aaagattttt tgagtagagt attataaatc tgttctatga attataaaag
    14581 gaagtcctaa atcatttagg acttcctttt ataatttgct aaggcatttt ataggagatt
    14641 acttttcttt ttgttaaaat aaaaagaaat agttgcatta tttgcataga agaaagggat
    14701 ctgttatggt ttcagtgatg tggtttcgta gagatttaag gattgatgat caaaaagctt
    14761 tagctcatgc tattgctagt caatcaccaa ccttatgtgt gtttcaattt aacaaggagc
    14821 aattaaatct gctacatagt cggaatcaat ctagttttat tactagcgtt ttggctttta
    14881 gaaagttatt aaaatgtgaa ggtattgact tatatctaat gtatggagac ttaatgacct
    14941 gttttgagca attattgaca caattaaaag actggacaga tgtgtatttt aactatgatg
    15001 aatctggata tggtcgttta cgtgatcaaa aagcagcaca atttttcaaa aaaaatggga
    15061 ttgctgttca tacctaccaa gatcactatt tacatggtag tcaagagatc attaaccaat
    15121 caggtcagcc ttataaagtt tttacgccct actataggat ttggcaaaat tatccgaaag
    15181 agactcctat taaagtagaa ctatcgcaag gcaggtggtt aaatcttgag acaccagatg
    15241 atgttttaag gactgttgag agttttaaag atgaaaaata tcaggatgtt gcaacttttg
    15301 atgaagcgtc aaaacaacta aatcgattta ttcaagacca attagcagct tatcacgcta
    15361 atcgagattt tccagcgcag ctagggacga gtcggttgtc tcctttttta agaataggag
    15421 ctattggcat tcgcacggta tatcacgctg tgcgtcaagc accaaatagt ctagggcaag
    15481 ctactttttt aaaagaatta gcttggagag acttttacaa tatggtctat gtggcttatc
    15541 ctgatcagaa aactcagcct atccaaaaag ccttttctca aatcgaatgg gttaataatc
    15601 ctgactggtt tcagttgtgg aaagaaggta aaacgggtta ccctattgtt gatgctgcca
    15661 tgcttcagtt acaaaagaca ggatggatgc ataatcgttt acgaatgata gtagcttctt
    15721 ttttaactaa agatctttta tgtgattggc gtttaggaga gcagtatttt caacaacaac
    15781 taattgatta tgatgctgcc agtaatatcg gaggatggca gtgggctgct tccactggaa
    15841 cagatgctgt tccttatttt agaatattta atcctgttac tcaaggtaag cgttttgatc
    15901 ccaaaggcga gtttattaaa gcgtatttgc ctcaactaga acacgttcca gagaagtatc
    15961 tccacgaacc gtggaagatg ccaaaatacc ttcaagagag tgtatcctgt attattggca
    16021 cagactatcc tcaaccaatt gtcgatcatg ctaaacaacg tgaacaagct attgcaaagt
    16081 atgagtgggc aaaagaaaaa gcaaaaatag aatgactgtt ctcattataa gagtttaaac
    16141 aaaaagttat catgaattaa gattatttaa tttaaaaaat aagttgactt tatttagatt
    16201 atttgatact attcagttgt ctcccttaga gaaagcgatt tcttgttttg gagctgattt
    16261 ttaccatttg gtcttagaat aggatgagta atatgactta caacgaggta tatcaagaat
    16321 ggttgcacaa taatgatctt agtgatgata ttaaagcaga tttagcagcc ataaaagaca
    16381 atgaggctga gattcaagat cgtttttaca aaacacttga atttggaaca gcagggctaa
    16441 gaggaaaact tggagcaggc accaatcgca tgaataccta tatggttggt aaggcagcac
    16501 aagctttagc taatactatt attgatcatg gacctgaagc ggttaaaaag ggcattgcgg
    16561 ttagttatga tgttcgctat caatctagaa catttgcaga attaacatgc tctattatgg
    16621 cagctaacgg tattaaggcg tacctttata aagggattcg gccaacacca atgtgttcgt
    16681 acgctattcg tgctttggga tgtatctctg gtgttatgat tacagctagt cacaatcccc
    16741 aagcttacaa tggttataaa gcttattggc aagaaggttc tcaaattttg gatgacattg
    16801 cggatcaaat tgcacaacac atggctgcac taactcagta tgaggaaatc aaacaaatgc
    16861 cttttgaaaa ggctctggac agtggacttg ttacttatat tgatgagagt attgaagaag
    16921 catataaaaa agaagtgctt ggtttaacga ttaatgatac tgacattgat aagtcagtcc
    16981 gagtagtcta taccccttta aatggtgttg ggaatctacc agtgcgtgag gttttaagac
    17041 gccgcggttt tgaaaatgtt tatgtggtac ctgagcagga aatgcccgat cctgatttta
    17101 caacagttgg ctatcctaat cccgaagtcc ctaaaacttt tgcatattca gaaaaattag
    17161 gtaaggcagt tgatgctgat attttgattg caactgatcc agattgtgac cgtgtggctt
    17221 tagaagttaa aaatgcagtc ggtgactatg tttttctcaa tggcaataaa atcggagcgc
    17281 ttttatctta ctatatcttt tcgcaacgat ttgacttagg caatttaccg gctaatcctg
    17341 ttttagtgaa atccattgta acaggagact tgtcacgggc tattgctagc cattatggta
    17401 ttgaaaccgt tgaaacattg actggtttta agaatatttg tggcaaggca aacgaatatg
    17461 atgtgacgaa acagaaaaac tacctgtttg gttatgaaga aagtattggt ttttgctatg
    17521 gcacttttgt tcgtgacaaa gacgctgtta gcgcctctat gatgattgta gaaatggcag
    17581 cttactacaa gaaaaagggg cagaatttac tagatgtttt gcagactatt tatgcgacat
    17641 ttgggtatta taatgaacgt caaattgcct tggagcttga ggggatagaa ggacaaaaac
    17701 gcattgcgag gataatggaa gatttcagac agacaccaat agctagtgtt gcagagatgg
    17761 cgttagacaa gacaattgat tttattgatg gctatcaaga ttttccaaag caaaactgtc
    17821 tcaaatttta tttggatgat ggttcttggt atgcacttag accatcagga acagagccta
    17881 aaataaaatt ttatttatat actattggcc aaacacaaga aaatagtgca acaaaattag
    17941 atgctattga agcagcgtgt cgcacaaaaa taaatcaggt taattaaaca tcaaaaatgg
    18001 ataacacttt tacactattt tccatataaa caactacaaa aggaggtgag acttttaggc
    18061 accttctttt tcttgtaggt gccactaatc aatttaatcg actcaaacca atactaaaaa
    18121 ataagtaaga gtataaagaa caggcatcta tttttttgtt ataatagaaa aatgaaatta
    18181 aagggagatg tcaatgacag aactaattga tggtaaagcc ttagctcaaa agatgcaaca
    18241 agagttagca gctaaagtca acaatctaaa acaaaaaaaa ggaattgtac caggcttagc
    18301 cgttattctt gtaggtgatg atcctgctag tcaggtgtat gtccgtaata aagagcgtgc
    18361 agctcttact gtaggtttta aaagtgagac cgttagatta tcagaattca tttgtcaaga
    18421 agagcttatt gcagtaatcg aacgttacaa tgcagataac actattcatg gtattttagt
    18481 gcagctaccc ctgccaaatc atattaatga taaaaaaatt attctcgcca ttgatcccaa
    18541 aaaagatgtg gatggttttc acccgatgaa tacaggtcac ctttggtcag gacgtccctt
    18601 aatggttcct tgtactccat cagggattat ggaattgctt cgagaatata atgttaacct
    18661 tgaaggtaaa catgccgtca ttattggcag atcgaatatc gttggaaaac caatggcaca
    18721 gctcttacta gacaaaaatg caacagtcac gttgacacat tcaagaacac gtcaattaga
    18781 agaagtatgt cgctgtgcag atgtgttgat tgtggcaatc ggacaaggtc atttcataac
    18841 aaaacaatat ataaaagatg gtgcgatagt gattgatgtg ggaatgaacc gtgatgataa
    18901 tggcaagcta attggagatg tggccttgga tgaggtggca gaagttgcag cgaaaatcac
    18961 ccctgtacca ggaggtgtcg gtcctatgac gattgctatg ttgctagagc aaacttatca
    19021 atctgctctc cgtagtactc ataaatagtt atcattagac aattcaacat aagagaatat
    19081 aagaagtcag caatggcttc cttttttgtt tttctgctca ctatttatcc agaaaaatgg
    19141 tataattgca ttagtatgca aagggactat gtcaggtcca actaagtgaa aggtggcttg
    19201 atggcagatt atttaaccgt cactcatttg acgaaatatt taaaattaaa atttgaccgt
    19261 gacccttatt tggaacgggt ttatctgact ggtcaagtgt ccaattttcg aaaacgacca
    19321 actcatcaat atttttcctt aaaagatgaa agtgctgtga ttcaagccac catgtgggca
    19381 ggagtctata aaaaactagg atttgaccta gaagaaggca tgaaaattaa tgtgattggg
    19441 cgagtccaac tttatgaacc gagtggttcc tattctatcg tgattgaaaa ggcagagcca
    19501 gacggcatag gtgccttggc tttgcagttt gaacaattaa agaaaaaatt aactgcagaa
    19561 ggttattttg agcaaaaaca caagcagctc ttaccacagt ttgtgtcaaa aattggggtc
    19621 attacaagtc caagtggcgc tgtgattcga gatattatca caactgtttc acggcgtttt
    19681 ccaggggttg agattttatt attcccaact aaagtacaag gtgatggagc cgcccaagaa
    19741 gtagtggcga atattcgaag agccaaccaa agagaggatt tggacttgct cattgttggc
    19801 cgtggaggtg gctcgataga agacctttgg gctttcaacg aggaaatagt agttcaggct
    19861 atctttgaat cgcaacttcc agtgatttcg agtgtgggtc atgaaactga tacaaccctg
    19921 gcagattttg tggcagatcg cagagcagcc acaccaacag cagcagcaga gttagcaacg
    19981 cctattacaa aaacagatct tatgtcttgg atagtagagc ggcaaaatcg ttcttatcag
    20041 gcctgcttga ggcggattaa gcaacggcaa gagtgggtgg ataaactatc acaatctgtt
    20101 atttttaggc aaccagaacg attatatgat gcctacctgc aaaaaattga tcgccttagc
    20161 atgaccctga tgaatacgat gaaagatcgt ctgagctccg ccaaagaaaa caaggttcag
    20221 ttggaccatg ccttggccaa tagtcaatta cagacaaaaa tcgagcgata ccaagaccgt
    20281 gttgctaccg ctaagcgttt actgatggct aatatggcta gtcaatatga tagtcagctg
    20341 gctcgctttg aaaaagcaca ggatgctttg ctatcactgg atgccagccg aattatcgcc
    20401 cgtggttatg caatgattga aaaaaatcaa gcactggtag cctctgtaag tcagataaca
    20461 aagggtgatc agttaaccat taagatgcgt gatggacaat tagatgtaga ggtaaaagat
    20521 gtcaaaaacg aaaacatttg aagaaaattt acaagattta gagactattg tgaacaaact
    20581 tgaaaatggg gatgtccctt tggaagaagc tatttcagaa tttcaaaaag gaatgcttct
    20641 ctcaaaagaa cttcaaaaga ccttacaagc ggcagaaaaa acactcgtca aagtgatgca
    20701 agctgatggc acagaagtag atatggatga ttaatggaca aattagctag aattgacgaa
    20761 gccattcgtc gctactataa gacgactagt aacggtgtat ctgaagagtt gattgatgct
    20821 atcttgtatt ctgttgacag tggtggcaag cgcattcgac cacttatctt attagagatg
    20881 attgagggat ttggggtatc gttacagaat gctcattttg atttggctgc agcccttgaa
    20941 atgattcata caggaagtct gattcacgat gatttgccag ccatggataa tgatgattac
    21001 cgacgtggta gactgaccaa tcacaaacaa tttggagaag ccacggccat tttggcggga
    21061 gatagcttat ttttagaccc ctttgggtta atagctcaag ctgaattaaa tagcgaggtt
    21121 aaagtagcct taatccaaga actttcccta gcttcaggaa cttttggcat ggttggtggt
    21181 cagatgctag atatgaaagg ggaaaatcaa gctttgagtc tccctcagtt gtcactgatt
    21241 cacctcaata aaaccggaaa attattaact tttcctttta aagcagcagc tcttgtaaca
    21301 gaacaggcta ttactgttcg tcaacaacta gagcaggcgg gaatgctcat cgggcacgcc
    21361 tttcagatta gggatgatat tttagacgtg acagctagct ttgaagatct tggaaaaacg
    21421 cctaaaaagg atttatttgc agaaaaagct acttacccaa gtttactggg gttagaagcc
    21481 tcctaccaac tgttgacaga gagtttagat caggctttga cgatttttca gacactagaa
    21541 aacgatgtag gctttaagcc tcaaataatt acaaaactga tagaagggtt acgacttaat
    21601 gcctaaagaa agagtagatg tgttagccta taagcaagga ttatttgaga ccagagagca
    21661 agctaagcgt ggtgttatgg caggcctagt ggtctctgtg attaatggcc aacgctatga
    21721 caagccaggt gacaaaattg acgatgggac tgagttaaaa cttaaaggtg aaaaactcaa
    21781 atacgtcagt cgtggtggat taaaactgga aaaggggctg cacgtttttg gtgtatcggt
    21841 tgctaatcaa attgggattg acattggcgc ttcaacaggt ggttttaccg atgttatgtt
    21901 acaagatggg gccaaactag tctatgccgt cgacgttggg actaaccagt tggtatggaa
    21961 actcagacaa gatccacgag taagaagtat ggaacagtat aactttcgtt atgctcagcc
    22021 agaggacttt agtgagggac agcctgtatt tgccagtatt gatgtgtcct ttatttctct
    22081 cagcttgatt ttgccagccc tgcataacgt tttgtcagat cagggacagg ttattgctct
    22141 cattaaaccg caatttgaag ctgggcgcga gcagattggt aaaaaaggca tcgtcaaaga
    22201 caaacagatt catgaaaaag tgattcaaaa ggtcatggat tttgcctcag gttacggatt
    22261 tacagttaag ggacttgatt tttcccctat tcagggtggt catggcaata tcgaattttt
    22321 agctcatctt gctaagtcac agacacctga aacgttagcc ccgcatttga ttcagaaagt
    22381 tgttgccaag gcacataagg agtttgagaa acatgaaaaa gagtgaacga cttgaattaa
    22441 tcaaaaaaat ggttttgacg catccaattg agacgcaaca tgacctctta agattattgg
    22501 cagagcatgg gttagaatta acccaggcta ctatttcaag agacatgaat gaaattggta
    22561 tagtaaagat tccttctggc agtggacgtt acatctatgg tctttctcaa gatagtggaa
    22621 aaaagatcgt tcaaggacct agatcgataa agagcactat tttagctgta tctgacaaaa
    22681 caaaaggttt agaacaacac ctctatttaa aagtcgtacc tggcaatagt aaattaatca
    22741 aacgttattt attagcagat ttttcaaaag ctatttttag tcttattgct gatgatgata
    22801 gtttattgtt aattgcaaag tctccttcag aagcagatat gatacgccaa gaaattttgc
    22861 tttggatgca gggtataacc tagaaaaaaa taggggagaa agtgatgtta ttagaaattt
    22921 ctattaaaaa ttttgctatt attgatgaaa tttccctaaa ttttgaaaat ggtatgacgg
    22981 ttttgacggg tgaaactgga gcaggaaagt ctattatcat tgatgctatg aatatgatgc
    23041 ttggtgcgcg tgctagtaca gaagtgattc gtcgtggagc taataaagca gaaattgagg
    23101 ggttcttttc ggtagatgct accccagaac tggttgcgtg tctggaatca tcaggtattg
    23161 ctatggaaga agaactgatt attcgccgag atatctttgc caatggcaga agcgtgagcc
    23221 gcattaatgg tcagatggtt aacctagcca ccttaaaaca ggtcggacag tttttggtag
    23281 atattcatgg gcaacatgac caagaagaat taatgcgacc acagctccac cagcaaattt
    23341 tggacgcttt tggtgataag gcttttgagc aattgaaaga gaactatcag cttatttttg
    23401 atcgttataa aagcttgcgt cgccaggtta ttgacaaaca aaaaaatgaa aaagaacata
    23461 aagatcgtat cgacatgttg gcttttcaga tagcggagat tgaagctgct gccttgagtc
    23521 gaggtgagga cgaccggtta aatcaagaac gtgatcgctt aatgaaccac aaacaaattg
    23581 ctgataccct gaccaatgcc tacgtcatgc tagataatga cgatttttca agtctatcca
    23641 atattcgctc tagcatgaat gacttactat caattgagca gtttgattca gagtacaaag
    23701 ggatgtcgac ttcgatttct gaagcctatt atattcttga agaagtgagc aagcaattat
    23761 cagataccat tgaccaactg gattttgatg gtgggcgatt acaggaaatt gaatttcgct
    23821 tggatacact caatagctta acccgtaaat acggtggtaa tgtgaatgat gtgcttgact
    23881 actacgataa tattatcaaa gaataccagc tattaacagg agatgacttg tcttcagggg
    23941 atctagaggc agaattgaaa agcttggaaa aacaattggt tgctgctgct tcggagttaa
    24001 gtgtctctcg ccatcaattg gcggagcaat tagaagctga gattaaagct gaacttaagg
    24061 aactttatat ggaaaaagca gatttcaaag ttcactttac cacatcaaaa ttcaatcgtg
    24121 atggtaatga aagcttggaa ttttacatct ctactaatcc aggcgaagga ttcaagcccc
    24181 ttgtcaaggt ggcttctgga ggagagttat cacgccttat gttagccatc aaggctgcta
    24241 tttctagaaa agaagataag acgagtattg tttttgatga agtagataca ggtgtttctg
    24301 gtcgcgttgc gcaagccatt gcccaaaaaa tttataaaat tgggcgacat gggcaagttc
    24361 tcgctatttc acacttacct caagttattg ctattgctga ttatcagtat tttatttcta
    24421 aagaaagtaa agaagagtcc accgtttcta aggtaaggtt attaactcct gaagaacgtg
    24481 tggaagaaat tgctagcatg attgcaggaa cagatatgac acaagctgct cttacgcagg
    24541 ctcgtgaact acttgccaaa cattaagatt atgtttggta tttgatattt tcataattag
    24601 atgacattga ttttttaggt gctaaaataa tcattgtgtc agaccatttt tcctctgtta
    24661 atctggcttg gtttgccttg acaaacctct gagaaatagt agaatagata agagaatttt
    24721 aagctgaggg gatagaaatg actagtaaaa aagcgtgttt atcaagcatc attgtgttag
    24781 caagtttaac gtgtggaaat gatactgtta gtgccaatca tctctcagca actggagata
    24841 agtttgatga ttgctcaaca cttgttgaaa aagatgtggc ccctaaagat gaacttgaga
    24901 tgttagcatg gtcctcgtct caaacaactg atgatgctga cagagactat gaagattttc
    24961 tcgatgatga ttcttttaat gatgattctt ttatttctca aaatgaaact gataagatgt
    25021 ttgagaattt aactgatgat aggttattag atgaattaga tgaagaagat acaattgagc
    25081 cagagcaaaa tgtaataatg cctagtgacg atgagctatt tgatttaact gatgctgttg
    25141 agacacgcct tactgtttct agtgctcccc atttagaggc tgaattgccg aaaccacatt
    25201 tgaggagcct atcagataca gcactgcggt ctggtgaaat tagaggacat ttagataaca
    25261 aactggacgc tttgtctgta acagctacaa agttagcatt aacgatggct caaaaatttg
    25321 atttgacaac gcatgtctat tctataggtg aaagctttag tgaagtatta gctgctcatt
    25381 atgaagacag aaaagcagaa tcagcttttt ctaagaaaaa gagatttcac cttcctattg
    25441 ctactccaga tgttgttata gaggagttaa ggcgcctggt ctcttctatt ggaagttcaa
    25501 aagaagatgt ttcagttcct tataatcgga agctaggtat ggcagttgca aaaagaaaaa
    25561 tagccctgcc acaaacggga gaggagttct cttattatcc agctttactt ggtttaatga
    25621 tattaggatt aacgccgatt atgataccaa agaagataaa taattaggta ataagttatt
    25681 gtagttgtaa aagacggggc aaatgttcaa gcgtgaaaag gttgactttt gcctcgtttt
    25741 gtatctcgtt attgctaagg cattttcttc gagcagctag tgctcgccat acctatctac
    25801 cgagtgacta ttcaatagca ctaccagttt tgctttattt agcaaggagt gttagaataa
    25861 agaggtgaga aactagttta gaatggaaaa atacatggga actataaaaa ttgttacaga
    25921 ttcatcaata actattgaac cagaattaat taaagcttta gatattactg tagtgccttt
    25981 atctgtcatg attgatagca aattatattc tgataatgat ttaaaagaag aaggtcattt
    26041 tttgagtctt atgaaggcta gcaaatccct tcccaaaacc agtcagccac cggttggtct
    26101 ctttgctgaa acttacgaaa atttggtcaa aaaaggagta actgacattg ttgctattca
    26161 cctctcacca gctttatcag gtactattga agcttcccgt cagggggctg aaatcgctga
    26221 ggcccctgtt acagttttag attcaggatt tactgatcaa gccatgaaat ttcaggtcgt
    26281 tgaggcagca aagatggcaa aagcgggtgc tagtttgaat gagattttga ctgctgttca
    26341 agctatcaaa tcaaaaacag agctctacat tggtgtatct accttagaaa atttagtaaa
    26401 aggaggtcgt attggtcgtg tgacgggtgt tttgagctcg ctacttaatg tcaaagttgt
    26461 tatggcactt aaaaatgatg agttaaaaac gcttgtcaaa ggtcgaggta ataaaacatt
    26521 tacgaaatgg ttagatagtt acctcgctaa aaatagtcat cgcccgattg cagagatagc
    26581 tatttcttat gctggtgaag ctagcctggc attaacctta aaagaaagaa tcgcagctta
    26641 ttacaaccac tctatttcgg ttttagaaac aggctctatc atccaaacac atacaggaga
    26701 aggagctttt gcggttatgg ttcgttatga ataatcgtca tttatttagt gggatatttt
    26761 tctttgttat tagtttatgt ctggcctttt tattgctaaa tattattatc cctaagtcaa
    26821 attcacgttt gaaaaagagt gattttctga aaaaagaaca agtagctatc caatatgttg
    26881 ctataggaga ttcattgaca gaaggagtag gtgatctaac tcatcaaggt ggttttgttc
    26941 ctttgttaac gaatgatctc agtgaatatt ttaaggctaa tgttaatcat caaaattacg
    27001 gcgtatctgg tgataccagt caacagattc ttgataggat gataaaacaa aagcagatac
    27061 agttatcttt aaaaaaagca gatataatga cgttaaccgt tggtggtaat gatgttatgg
    27121 cagttattcg gaagaattta gcggatttgc aagtttctag ttttagaaag ccagctcgtc
    27181 agtatcaaaa acgattaaga cagattatcg agttagccag aaaagataat aaagatcttc
    27241 ctatttttat tttaggcatc tataatccgt tttatttgaa ttttccagaa ctaactgata
    27301 tgcaaaaagt gattgatgac tggaatatca aaactaagga ggttgttgga gaatacgatc
    27361 gtgtgtactt tgtgccaata aatgacctct tgtataaagg gataaatgga caagaaggaa
    27421 ttgtccattc ttcaggagat caaactacaa ttgtcaatga tgccttgttt actggggacc
    27481 attttcaccc aaataatact ggctatcaaa tcatgtcaaa tgcagtaatg gagaaaatta
    27541 aaaagcatga aaaaaaaatc aaaccttaat tggtggaagt ggagcttctt atgtctgctt
    27601 gcttttaata ccgccttttt gatggttatt gcaagtcgtc tcattcaagt aagagaacct
    27661 gagtcagaac tgattgctaa aaaaccagtt aaaaatatca aaattggtac atttgtcaca
    27721 accagagaac agcttaacga aactgtagca agttatctta aagattatca gactaaaaaa
    27781 atgtcttata aattttatgc gacatcttct tctattttgt ttgaaggaac ttatcaatta
    27841 ttagggtatg aagtcccttt atatatctat tttcaacctc atcgtctaga aaatggagct
    27901 gtccaactac aggtgatctc tttttcagtg ggaactctgc cactcccaga aaaagatgtt
    27961 ttgcagtatt tgaaatcaag ctacaaattg ccaagctttg ttaaagtgat gccaaatcaa
    28021 tcagctatcg ttgttaattt acaagatatc caaaatgatg ctaaggttta tttaaaagcc
    28081 aagaaaattg atttatttaa tgatgaaatc agttttaaca tctataagaa ataagctcaa
    28141 ataacgttaa atacttgacc taatcgcttt ttttagatat gataatatct gttaaagcat
    28201 taagcttact aattatttgg aggatttgtt aaatggctaa caaacaagat ttaatcgcaa
    28261 aggttgcaga agcaactgaa ttgactaaaa aagattcagc agcagcagtt gatgccgtgt
    28321 tttctacaat cgaagctttc cttgctgaag gtgaaaaagt acaattgatc ggttttggta
    28381 acttcgaagt acgcgaacgt gcagctcgta aaggtcgtaa cccacaaact ggtgcagaaa
    28441 ttgaaattgc agcttcaaaa gttccagcct tcaaagctgg taaagctctt aaagacgctg
    28501 ttaaataatt gcatatataa aagcccattg tacaagcgtt gtagcctgtg cagtgggctt
    28561 ttttgtgttc aggggggtaa aaaaggggta aaaaatttaa tagttttcca taatatcagc
    28621 tacacttgat ttcattttct ttgtgacatg agtataaatt tgggcagtag ttttagcgtc
    28681 tgcatgtcct acacgttcca tgattgattt tagcggcacg ttattctctg ctagacggct
    28741 aataagagtg tgacggaaga tgtggctagt aagttttttt gtaattgggt cttccaatct
    28801 ttcattagct ttttttaaag ctaagttgaa tgagttagtc tgaattggaa caccgttttt
    28861 tgttgtaaaa aggtatccca tatctctata tctatgattt gtattttttt ctagttcgtt
    28921 cataaattct aactcttgta gaatttcaag ttctctactt gtcatgatgg tttcacgata
    28981 agaagctaat gtctttggtg ctgtcttttc cccgttacga tatccttctg tatgatcaaa
    29041 tgttccgtgc aactgcaata ttcttgactt agattcgtag ttgcacggct caatgctgac
    29101 agcttcaccg atacgacaac cgttcaaact gataaactca gccaacaaac caagtcggta
    29161 agtgctaggt cttctgtaca attctttcaa taatggttta atttcatctt cttcaagata
    29221 tttttcttca gcctttttcc agtcttcaag agttttcttt acccttggga gtttagcacg
    29281 tcttgcagga ttatcttgga taatatccaa accaacagca taatcaaatg ctaagtttag
    29341 catagactta ttacgctctt ttttattcct agagcaatct aggttatcga gataattctg
    29401 aacgtattta ggatcaatat tcactacttt aacacctatt ccaaaagttt cccttatctc
    29461 ttcgatatta cctctcagag aagctacaga cgacctttta agttctttct tataaaacgc
    29521 ccaccattca tctaaaagtt ccgtgaaaag taactcagag gcctttaatt gcgctatttt
    29581 ttctgttatt ttttgttcaa ggatttttcg agctgcttta taagctcttg aattatcctt
    29641 ctccatagta acggatacag gtttccatgt tccagtgtaa ggatctttat aattttcacg
    29701 aaatttgaat ttaccgttat cagtttcttc tatccacatt tgttttttac ctcattttct
    29761 gttaaaatag gtatagtaaa gagacctact gcgaagcagg tttttactat actagattcg
    29821 cctcacgctc tcctcgccaa atttgagcgt ggggcttttt tgttagttga gaaaccaaga
    29881 tgctatcgac tctaataatc cagcattttt actttttgat actctatcta cttttaaaat
    29941 agtcaatcgt aacttataag ttatatcttt ctttttagta accacggtct ttaaatcgtt
    30001 tttgagtgtt ttgtattgtc caccacgacc agtaagggtt gcttccattt ggtaatgact
    30061 agattttttt acataagggg ttaatcgttt agctaagtct gctggaaagt agccaacaaa
    30121 agttttgttt accatgactt ttatggcatt tggatcgtga cgattaagag gttctctgac
    30181 aatctctaca tcttttgttg agaccctgta atacttgtag atatccttga agtttgattt
    30241 tatgtagtca gaaataaaat ctttatcctt atcccagtat ggtgatttct taccaatttc
    30301 agccataact ttattagctt ctttttcatg ataatttgtt cccattaaga gaaagttatc
    30361 ttggaatatg acttttgcca taacagtctc ctttaatatt ccctataaat atccacaact
    30421 tcaccgattg tgcggatgtc gtcatccttt gatagataga tttcctcata gcttttattt
    30481 aaactttgca agtaccaagc gccatcataa tcacgcttga gtttttttac aaagttttta
    30541 ccattgactt ggaatatccc tatatcattc atatcgactt ggctagatac cttgatgaat
    30601 agcaaatcgt tgtcttgaat aagtggttcc attgaatcgc cagctacttt tgcaatagta
    30661 tcatactcat cggggacatc atcagaacgt agtttaactt tcatgtgtaa attgtcttct
    30721 tggtatgccc caagaccagc ggcaaccaat ccctcaacgt agtcagtgat ataatcttct
    30781 gtctcctcag attttttatc gaatatagaa acggttttat tttgttcttc taattgttcg
    30841 ttagcgaagt tgaggacttt ttcttgtcta ggttgttcta gttggttgta tatagaaacg
    30901 atttcaggtt gttcgttctg tattgtgatt ttcccaagtt tactatctgt gagtcctaaa
    30961 agatagtcag aggtaacgtt gaaaatctct gctagttttt ttaggtcttt accttttgga
    31021 aaattttcat tcttctccca ctttgaaaca gtagtatagg ttttcatgcc caatatttct
    31081 gaaagttcag tctgagtcat gttgcgccct tctctcaact ttcttattcg gtcccctaat
    31141 tgctccatag gatacctcct ttttaatttt gataagtaaa ttatatcaaa accatgatta
    31201 taaatcaacc atataagaaa aaagttttaa ataaactata tgatttacga ttttttcaaa
    31261 aaaacagaaa ataaatcata taaaacactt gacgcaagat ttaaaatcat atagaatgta
    31321 atcatcatca agaaaggagc gactcagcta tggtaactat tgcagaatta agagctaaac
    31381 ataataagat gtcacagcgt gaattggcaa aagaattagg tgttactcaa acatctatca
    31441 gcaactggga aaaagaccag acaaagattt caggtgagta tcttattagt ctagctttgt
    31501 ttttcgatgt atctaccgat gacattcttg ggataaacaa gcaagcaaca caaaaatttt
    31561 aaacactata tgattttaaa tcatatagta gaaaggacac acatgaacga aataacattt
    31621 accctatatt gcacaacatc tgaagaagca atcacggaag taaagaaact aaaagaagcc
    31681 catccaaagg atagacttcg attcaatgta aacattaagc ctgagtttta ctaatagaac
    31741 caacttaatt agataataaa aagtccgacg ggaatcggac tccaaacaaa aaatatttac
    31801 ttaattataa cacaagagag aggatattaa tatgccaaaa gcagaaatta cttatagagc
    31861 agttgatgtt aatgaaacag cttctcatgg tgattataaa cacttgattc aacaatggga
    31921 ggggttgaca gttgctactg caaagcagtg ggcgacagaa atgcgtgatc atccagactt
    31981 taaacagttt gtattaaatc caacgcatag aatcgtattc attgattaca aaggattcaa
    32041 actgtttgta cagtggaaat ctcgcaatcg ttacaaaaca aaaaaagaga cactgccaga
    32101 aatgcttgaa aatattaaat ttgaaaaaag agtaggagta taacatgaac aaattagaat
    32161 tatttttgtt agcaacaacc gttatcttag cggtcattgc tagggtgcaa cacgaagtca
    32221 ttaaaaaaca caattcgcca gagaataagc ggaaaatttt tagggaagta gctttaaaaa
    32281 acagcaaagg atggagcaag aagcgtgcaa gaggaggggt tgtcagctaa tgcagtacat
    32341 ttttcaagac attaacaggt agttacacag ctgttagcaa tgaatttatt caggacaaag
    32401 aacttttcaa taaggaaaaa ggactgctgc taaccatttt gagtaatgca gacgaatgga
    32461 gagtctatcc tgaagaactc gctagacgtt gtaaggatag cgaatctgca atcagaagcc
    32521 agttgaaagc gttagagaat gccaagtata tcagaactta tagaaaatca tttggcgggc
    32581 gatatggtac cgaagcctat agattctgtt ctgacagaaa aataagcgac gaggcgttca
    32641 atactttgaa ggcagaacag gacttagaac tagaaaaaat tgctaatacc taatttgcta
    32701 atgtgcaatt tgctaatgtg caatttgcta atcaacaaat tagccaacta ataaatacta
    32761 acttataaat aaatactaaa taacaataaa tactaacaga taataagcat catcatcaac
    32821 atcaggagga gctatggacg aaaaaaagct ttttgaaaat ttccaattaa cttttggacg
    32881 gatgatatcg ccatttgaaa tcgaagatat tcaaaagtgg attcacgaag ataacatgcc
    32941 aattgaagtt gtcaaccttg ccttaagaga agcggtagaa aacaacaaaa tcagttggaa
    33001 gtatatcaat aaaatcttag ttgattggta taaatctgga gatacgacag tagaaaaggt
    33061 cagagacagg ttgcaacggt ttgacgatag taaaaaacaa cgaagtgtaa ctacctcaaa
    33121 cgtcccaagc tggtcgaatc cagactacaa agaaccagat ttaaaagaat ttgctctagg
    33181 aagcatggac ggtatagaag atggatcagg agatttttaa tttttttaac aaacaaatca
    33241 aaaaagattt tggtaaaacg gcgagtaaag agacttttgc taagtttgct agttactgcg
    33301 ccgaaggaat cgaaaaaaat ggagttaagc caatttttaa ttggataaac ctatacgctt
    33361 ttggaactgg tatgacaaca gcagaagcag accggttgag aatagagcga tataaacagg
    33421 agaatgcgtt atgacaaaac aacatagaga aacgcttatc tggtaccgag caagtcatca
    33481 agagcgtgag agattgcttg attttggact agttgataaa gcacggtacg tgacactatt
    33541 gcggcaattg cgtaagaaat atgcgattta ggaggaaata tgacaccaga acaagcagaa
    33601 aaagcaaaaa tcagagctaa acaagaactt gaaacgttta gcatatacct tgatcaggca
    33661 attgatgatc tcggtggagt tctaacttca cgagaagtct ttttagcagc gggaataaca
    33721 tatcttggcg caggtcagac agatatacat gctgcagtcg agggattatg tgagcaaatc
    33781 caatgatttt aaatttagtg aagactggga gagcaactaa aacacaaaaa gaggaaatga
    33841 aatgaacatc aaagaaaaaa ttgtagtgct aagaaacact gaagacggaa gttttttaaa
    33901 gagtttcaaa aacaaaaaag atgtacttgc ttataatgtg gaacttacag atagcattca
    33961 actggcatca tttttaccag aagaagctta caacatacaa aaagaaaaaa attgataatt
    34021 tggcagaaac gcttgggtgt gatgttgtag ttatcgaagc atcatatgac ctaaaattta
    34081 ttgatggcga atcagtgcca gagttaacaa aagagcaaaa agttaaaagt atggtaaacg
    34141 gaatgtttga gcaggttttt ggaggtgaat agagatggca aatcaattat caacatacac
    34201 acacaaacaa ttttttaacg caccaacagt tcaaaaagct tttgatgacg tttggaaagg
    34261 cgccgggaca cagttcgcgg taagcatctt gtcagtacta caaggtagtc aaagtttgaa
    34321 atcggcatct aataaatcta tttatgcagc agctatgaaa gcagccgtgt taaatctgcc
    34381 tattgagcca agcttaggaa gggcctattt agttccgtac aaaggtcaag cacaattcca
    34441 attaggctat aaagggttga ttgagttagc gcagcgcagc ggacaataca aaaatattaa
    34501 tgcaggtatc gtctataaat cacaattaat ttcttacaac cctttgttcg aggaattaat
    34561 ccttgacttt agcaagccac aagatgaaat tgtagggtat tttgccgctt ttaaactttt
    34621 caatggattc gagaaagttt ctttttggac agtagaaaaa gtaactgcac atggaaagaa
    34681 attttcaaaa tcgtttgcta gcggtccttg gaaaacagac tttgatgcaa tggctcaaaa
    34741 aactatttta aaagatattt tgagtaaata tggtccgtta tcagttgaga tgcagaaagc
    34801 tatcgaggaa gataatcaag attcaacgat ttctacccca aaagacatta ccccacaaga
    34861 agcaaatagc cttgacgacc taattggtca ccagaacgaa aataaggatg ctcctaacaa
    34921 tttaaaagac gtaactgaag atttacatga cgaagaagaa aaaacgctca cagacgaaaa
    34981 taagacggtt ttagaagata cgtcttatcc agcagatgag gttcccgatt ttgaccaaga
    35041 gactggtgaa gtattagcta gcgaaggcaa cttatttgat aacctcggag acttaatatg
    35101 attaaacttg taaaaattga aggatattat attaatccag aatatgttgt tggcgtttgg
    35161 gaaagatctg ctttaaattt tgacgattta gatgaaaaag tagtggttat tcaattcgtt
    35221 ggagataggg aaagggaaga gtttgtcttt tgcgatacac ctattgatga agtaattaag
    35281 aggttgctag atgactagtt tagacttgct cggaaaggac tattacagcc gtgaatcagc
    35341 tatcaggtac tggtccatta gtcagtacaa gcgttttaaa gagtgcgaag cgcgggcgct
    35401 tgctgaatta caagggaatt ggacagatac cagagataac actgcgttgc tcgtcgggaa
    35461 ctatgtccac tcttactttg agagtaaaaa agctcatgaa gaattcaaag cccaaaacgg
    35521 ctctgaaatg atttcgaccc gaggagcaac aaaaggccaa ttaaaaaagg attacttagt
    35581 tgctgaacag atgattgacg ctcttaaaag tgatagtaac tttatggcta tctaccaagg
    35641 agaaaaggaa gcagcaatca caggatttct tggcgagatt gaattcaagg gtaaaatcga
    35701 ctgcctgaat gttgaacgtg gctattttgt agacatcaaa acaacaaaag ggccgattga
    35761 cgacacgatt tggagtggcg aagagcgtgt cagatggttt gaggcttacg gatatatctt
    35821 gcagatggct gcttacaaaa ccatgttaga agctaaatat aataaaccgt tcgagccgat
    35881 tatttacgcg gtaaccaagg aaacgccacc agatacaaga gccatcagaa tccaaaatgt
    35941 agacgctatg caaaacgagt tagatagcct agcacaaagc attaagcgat tagatgacgt
    36001 taaaaaaggc atagaaaaac ctaagccttg cggtcattgc gagtattgca gggctaatca
    36061 attaacacaa agagtaatga ttttttagga gataaaataa tgataataga gaggaataag
    36121 cggaggatat ggtaagaagt gagtatgcta gagctaacca catctctaaa gaatgggtag
    36181 tactttacta gaaaagtgga ggaatttaaa tgattgaatt cgtaaaagaa gtaggaatgg
    36241 ctttgttatg gctgtttgta ggatatcttg ttggagagcg tagccaacaa aaaaataagt
    36301 aaaaaatacg tgccgtgaac cacgaaaaaa gcgaactaga aataagtgtc atttaacggt
    36361 catgtgacta gaatgatgta aagaatagcg actgcccgta tttagccaaa ttaacaactt
    36421 ttggcagtcg cttttagttt tagggaaatg ctatggatga attaaaagag aaagcattat
    36481 ccaaaatgct agatgaaatg aacaaaaaac atagtgcggc tgaagacgcc atacataatt
    36541 ggctatctga tcaggatgac gaagaactat tcaaaggcat acttgacgat aagaaatcaa
    36601 ttaaagatgc catgaagtac tgcatcaatc aggcacaaaa acaaaaaaca ggtaattgcg
    36661 ccatggttga cgataaaaca gtattcggtt gggtccgtgt gtatttcact ggaaaaacca
    36721 aaaagatcga accagttcaa gcaactgtca cagttagcca agaaaatacg aaagttatac
    36781 caaagaaaaa taaaaaatca aaaggtgtgg ttgagggcca acttgaccta tttggtgcgc
    36841 ttgtatgaag aaaaaccaaa agattatcga aggtcgttta aagccaccta aggcattctt
    36901 tgactggtgc tatgaacaaa tacccaccat cagatggcaa aacaaggaaa agacaatcga
    36961 aactgaacgt gaacacaaag tctatattga taataggcgc ttgactaagc ggactagact
    37021 agatttcttt gataagtttt acagctttgc tattgtcctt gtcacttcca agcgaattga
    37081 aattcaatcc tatggctttt actccagata tagcaatgga agacaatcga ttgaagtgaa
    37141 gttgtgtaac tttgaaaaat tggccaacaa tcatcacatc aaattgactg aacaatttgg
    37201 ccagtatgtg cctggattaa caccaaattt tataggctct ggagcctatt caggtaccaa
    37261 attttatcct gatgattggg aagaaaaaat caagtcaata tcagaactga agtatttgca
    37321 atttccgatc ggcttagcac atcataactt gccccacatg tataagtaca gaacgcaaat
    37381 agagttccta caaaaaatcg atgcttggaa gatagcaaat gatttggctt atgatgtgac
    37441 tgaatacgat gcttggcatg tacggaaagc cgtagattgt cgagtgatta ccaaaaaatg
    37501 gttacaccag aacaagcaat tcttcaaaaa cagtaacagg agttttagag aatatgagct
    37561 tgagcgtcga attaaagcta gaaatgggaa gttggttcct ggtattgaaa aaatattgtc
    37621 ttatcaagac atcaataaaa ttccaaaagc ggccaaaatc aacaggtttc aaaactggtt
    37681 ggttaagaat aaggtagatt ttaactatta tatcgattat ctgagtatgc ttgatgaatt
    37741 aggtattgaa attgacactg ataatctgat tatgccaaaa gacctagtaa aggcccatga
    37801 taatgttgtc aaattagtca atcaaaagaa aagcgagatt gaaaaacgca aatttaaaaa
    37861 tcgtctcaaa agcctttcta aatatgagca aacgattggc gattactgtt tcagagcacc
    37921 tgtcgattca ggagaactca tccgagaggg gaaaactcta tctcactgcg taggaagcgc
    37981 acgatataca caggcccacg cttctggaaa aacaactatt atttttatcc ggagaaaatc
    38041 tgattcagac aaaccatttt acacaatgga gtataaagcc ggccatatcg ttcaagtcag
    38101 aggcaaacat aatcagtcag ctactgaaga agtccaaaaa gtagttgatc agtggctggc
    38161 cattgtaaac aaaaattata aacacgcata ggagaaataa catgataaca aaaattaatg
    38221 ttccaaaaac atccatcgta attgaaattg aaaacaagga aatcacgatt gagaatttga
    38281 ttaattatga tattaaaatg attttcagaa atcaggataa tgaaccgtct cttgatgaaa
    38341 acggggacat ctttgaaccg atgtactggc tagacataaa agctaaacct aatgatgaga
    38401 ttgagtatca cagcagctta ggcgtcaaaa aagaaaagag aagactcgct gaactacaaa
    38461 tcttctttga atatattgaa gcaaataaac aaaatctctt tgacctctgt gggctaaaag
    38521 gagaactcgc atgagtagct tgacattatc acttgatgtc tctactactg gaacgggttg
    38581 ggctattttt gatggttcaa ctctaatcca gagcggggct agtaaaccaa aacaaaaatc
    38641 attctatgag cgtgccaaat caatggctag cgagctaaaa actatccaac ttagagcgat
    38701 tcagaaacat gataagcctt ttgaggacat tgtgattgaa cagaacactg tacttggacc
    38761 gaatcaacag tcgtctataa aaatcgggat tgcaactggt attatcttag ggagattact
    38821 tgctgaagag atttattttg taaatgtatc gacgtggaga aaatactgga aatttagcta
    38881 taaagaccgc tcgaaaaaat ccatgaagaa acaggcaatc aatgcagtag ctgcggaatt
    38941 taataagcaa gtgaaggatg acgaagctga cgcgatactg attgggtctt actttactaa
    39001 tcttggaaag gattttggcg acttagaaag tcacaaaaat tgagagaata aagtgacata
    39061 taaagtggag gtaatgaaat ggaaattgta aaagatggag ttaagtttat tgccagtatg
    39121 ataattgttc tggcagctac atttggctgt ggatatctgt tttaccgtgc aggatacgaa
    39181 caggcgaaaa aggaagttca accagttacc atctataccg tcgataatgt aggtggtgta
    39241 atggtaggag aaattacgga taaagaaatt atagagggac ggtacacggt cacggctcat
    39301 gcctacggta agtttctagt aacaaaagaa cagtacaagg cgataaaagt tggcgataaa
    39361 atacctgact atttgaagaa aagaggtaca aaatgattga gttaacacaa aaacaggctg
    39421 attatgttga gtttgtcaga aaaactattg tagatccaga tatgatggaa ttcgcggtaa
    39481 atacacaact gattagctat gctttacttg ttggatattg cattgttgat gaagaggtgg
    39541 ccaaatgaaa cctagaaagt atccgtattc aggaaagata agaattataa aaaaagaatt
    39601 accaaggttt gtaagattgg gagattttgc ttttaatagc aacctagtta aacatattga
    39661 taaaatcaga caagtaaaac caaatgaaac gctaattcgt ttcaaaatcc ctaagttgtt
    39721 tatgacatat gaagaagaaa cttttaaagt aagacttgag attgataaag tcgtaaaaat
    39781 attgaaccaa tactaaacaa aaaaagccag ctcacagctg accattggtt aataattcga
    39841 taaatctatt ataccaaaaa ggagttagga agtgagcaaa gctaaggcaa ttttaaaaga
    39901 cttacgcaat ttagatttat atatcgctag tttaattaga cgtcaggaaa agattgagac
    39961 ctcattgctt tctagcccta aatggtcgtc cgataaggtt aatggtggta taaaacgtaa
    40021 gcaagatgat gtttacgtag agttgattgc aactgccgaa gatatcgaga agaagactgc
    40081 cgaagctata agaaaacaaa gagagcttca gaacctgatt gatagccttg aaaatacaga
    40141 cagtcaaaca attttaagca tggtctatat tgataagatg actagatggc aagtgattga
    40201 tgagctaaat tgcagcgaaa gcacctattt cagactgtta agagttgcaa ctaaggaatt
    40261 aaataatttg acagtaaatg acagcgattg acagtgaata acagtgcatg acagttttaa
    40321 agtgataata tagtattatc aagaaatgag ggacaggtaa gaaaataccc ccctctttta
    40381 aatttagaaa ggccccctat gtctcaatta agggcagata aaaaaggtac tcacagggta
    40441 gcatttgaaa agaataagcg aaagctgtta aagactacca acctctgtgg tatctgtggt
    40501 aagccagtcg ataagacact gaagtatcct cacccgctta gcgcagcaat agatcacata
    40561 gttcctattg caaaaggtgg acatccgtca gcgctagaga acttacaact tacacattgg
    40621 caatgtaata ggcagaagtc tgacaagttg ttcgctaacc aagcaagcaa cgagccaaag
    40681 acaataggaa atagaaacct tcctcaaagt cgagactggt catcttttac attaaaaaag
    40741 tgaatttgtg caaattattg atttatgcta aaactggtca gaagctaaac ggggggtatg
    40801 gccctccccg gtcggccggc cgagcttcac gccgtcactg tacatttttt ctcacgttag
    40861 gatttagaaa attttggagg ttgaatttca ttgaaaaaga aatgcttaat ttgcaaaaaa
    40921 aacttccaag caaaaaccaa tagaacttta tattgctctg aagaatgccg taagaaaggc
    40981 aatcgtgaga aacaacgtaa attgatgaaa caaaaacggg ctgaacagag gaaagaaaaa
    41041 aagaaagtcc taaatcctaa cacagatgtg acagaaaagc ctaaaaaaat acgtaattta
    41101 gcgcagcact ataaaaaact aaaaaaggaa attttggcaa atgaatctga atttggtttt
    41161 actggaataa cacttattga aggaatagat gtacatgaag aaaactttgt agatttagtc
    41221 atgcaaaaaa taaaggagca gaaatgaatt atatgggtat gggctatctt cgtaggaagt
    41281 tagctctttt taaaactgga gttgataaaa gatatcgtta ttatgccatg gatgacagag
    41341 acgacacacg aagtattgtc atgccaaata atgtgcgtga aatgtacagg tctgtgttag
    41401 aatggaccgc taaaggggtt gatagccttg cggaccgtat tattttcagg gagtttacca
    41461 acgatgattt taatgcttgg gaaattttta aagcgaataa ccctgatatc ttttttgata
    41521 cagccataca gtcagcatta attgcatctt gttgctttgt gtacatcatg ccaggagcgg
    41581 aagacggctt acctaaaatg caagttatcg aagctagtaa agcgacgggg atacttgacc
    41641 caactacatt tttattaaca gagggttatg caattttaga gtctgactca aacggtaatc
    41701 ctacgttaga ggcctatttc acagacaaag acatctggta ttatccaaaa aaagggaaac
    41761 catataatat taaaaatcca acaggtcacc ccttgcttgt acctatcatt cacagaccag
    41821 acgcagttag accatttggt cgcagtcgca ttaccaaggc tggaatgtat catcaaaagg
    41881 cagcgaagag aacgcttgag agagcagagg ttacggctga gttttactca ttcccacaaa
    41941 aatatgtttt gggaatggat ccagacgctg aaccgatgga aaagtggcgt gctacggtgt
    42001 caacgttact cgaaatctca aaagacgagg atggcgacaa gccaacagtt gggcaattca
    42061 caacagcaag catggcccct ttcatggaac acttgaaaat gtatgcttcg ctatttgctg
    42121 gtggttccgg tctcactctt gatgaccttg gttttccatc tgacaaccca tcgtctgttg
    42181 agtcaataaa agcggcacat gagaatttga gagcagcagg acgcaaagct caacgttctt
    42241 tttcttctgg atttctaaat gtggcgtata ttgctgtttg tttaagagat gaatttcctt
    42301 atcttcgtaa tcaattcatg gatacagtaa ttaaatggga gcctctcttt gaagctgatg
    42361 caaatatgct aactttagta ggggatggag ctatcaaact taatcaagct atccctggtt
    42421 tcatggatgc agatgttatc cgtgatttaa cgggagtaaa aggggctgat aaacctatac
    42481 ctgctatcac ggaggtaaca actgatggtt gatgatgtct tacctaagct actaaaatct
    42541 gttcgacaag attttgaaaa gtattttggc gaaagtgatg ttgtaaccaa ggcttttgca
    42601 gaattgcaag ctaaaaaagt gacctataaa acagtcaatg agtttgctat tgaagtcgga
    42661 agacttttat ctttggctct gacaggttct gttagctcgg ataaattacc agacggtaaa
    42721 atgtattaca atatcgctaa gcgtctctta gatgagacta tgggacggaa ttacaaattg
    42781 atttcaggtt atgctggtga tgttcagcgg attttaaatg agaatgctca gattggtcta
    42841 aaggtgcaac gtccaccgct aaatcgagac aagattaacg ggatggtaaa tcgtttggat
    42901 agcgagaata catttgatga tgtaaaatgg ctgtttggtg aaccgattgt taatttttcg
    42961 cagtccattg tggatgatac catcaaggca aatgcggatt tacaatataa aacaggtatg
    43021 acgccacagg ttgtcagaac agaaagtggc aactgttgtg aatggtgtcg tgaggttgtt
    43081 ggcacttata gttatccaaa agtccctaag gacgtatgga gaagacatca gcggtgtcga
    43141 tgtacgcttg actatgaccc gaagaatgga aaagttcaga gtgcttggag taaaatctgg
    43201 cgaaagaaag aaaaaactca agaatctata gaaagggttg aaaaatttaa ggaaagtgct
    43261 ctagtagaat ctatcaaaaa tgatatcgct aagttagata tgacaaaggt tggtccgagt
    43321 gatataattg atatagggaa acgtatcaat tatcacttta gagtttcaga acatatagga
    43381 gataaagaga aattaaaaga aattttctca aattttcgtg aaatcggtgg agaaatacct
    43441 aaaaatactt gggcaaaagg ttcatctaaa cttgttaaag accagctaca agaggctttt
    43501 caaaattatc caactgagtg ggcagctgtt ccggacggta ttggtaaaaa actaaaagct
    43561 ataaaaagga agcgcggtta cttcgatgga tatgatgaag atttagttat tgctacaaat
    43621 ggaacaagaa aaacaacacc ttaccatgag ataggacata tgattgaact ggttaatcct
    43681 gatttagtaa gattagagaa agcctgggta gataaaagaa ctgctaatga agctgaggtt
    43741 cgcttgaaag atatttttcc aagttcaaat tatggtattg gggaagttac taagaaagat
    43801 gactttatat caccatatat tggtaaatac tacagcgatg cagctgaagt tttcactatg
    43861 ggattacaag gtatttttgt tcctgaagaa cgatttgcta agtcctttga caaaaaaaca
    43921 tggaaatatg actacaagac aatcaatgac gaccctgaat ttttgaattt tattattgga
    43981 ttatttgtga aagtgtgata aatatggaac caaaattaca tcggcaactg cgtcaaaaat
    44041 atgacgacgc tgaaaaacaa tatcttgaaa agtttggaga agactcgctt gatagagtat
    44101 ttttttggga gccagacgtt tactttgatg agtggaaaaa ggttctacca gatgcaacac
    44161 tggaattaaa caaagctatt aatagcgggg tggcgattga tccagatcca gaaaacgcaa
    44221 tatattaagc acctagagca atctggtgct tttcttatgc ccaaaaagga gaaaagcatg
    44281 aataaaatat cataaaatgt cgaaatgact tgggaaaaca aagacgaatt tcaacaaatc
    44341 atgaataaag tcaatgaaac aaaagaagct tacgaaaaag ccttagaagc tgcggaaaat
    44401 tttgtcccta aaatgtcgtg tgcaacaaag ttaaataaag gagaaggtaa tgaataaacg
    44461 tatcaagaaa aaacgtaaat tggaaacagc tattatgcta ttgattgcag aaaatgcctt
    44521 gcaggctgaa gcaattaaaa atcaaaacaa agaaatcatg gagttgaaat caattgttca
    44581 gcggaacgct ctggcaacaa acgaagagtt agcgactgtt aaagctgcta ctttagataa
    44641 ccaatcagtt atcaaggcaa tcggtgacac ggttgactac atcaagaaaa actacaaacg
    44701 taagtggggg aagtgatatg aaatatcgta agaaaccggt cgtagttgaa gcaattcaat
    44761 ttacgggtac aaactatgaa aaaatcaaag agtttattgg tcaaaatacc ttatgttcga
    44821 ctttgagtat tgtaatcccc actcttgaag gcgactacat catcaaaggc atcgctggtg
    44881 aattttatcc atgtaaacct gatgtttttg aacagactta tgaatcaact taaaccaaag
    44941 tcgtagcaat acggcttttt attgtgccct gtcgcatggc taaaaactag gcagtacgat
    45001 tgaaaggaat aagtatggtt actaagacga aaacaaagct tggcaatcag cgacctactc
    45061 aatcggtaaa tttacatttt gctaaatctc tagcgcatga agctattaat tactacaaaa
    45121 aaacagggct aagctgctat ccatggcaag taaatatgct tatcccaatt atggccatag
    45181 atgaaaatgg tctgtgggtt catcaaaagt atgggtatgc tatcccacgg cgtaacggta
    45241 agacggaagt agtctatatt gttgagctgt gggctttgca taaaggttta aaaatcttgc
    45301 atacagctca tcgaattagc acatctcatg catcattcga aaaggtaaaa aaataccttg
    45361 agatgtcagg ttatgttgat ggagaagact ttatatcaaa taaagccaag ggtcaagagc
    45421 gtatagagtt caaagccagc ggcgctgtta tccagttccg aactaggaca tcaaacggtg
    45481 gacttggtga gggatttgac ttacttatca ttgacgaggc acaagaatac acatctgagc
    45541 aagaatcagc attgaagtac acagttactg atagtgataa tccaatgact attatgtgtg
    45601 gaacgccgcc aacgatggta tctactggta cagtatttga agcatatcgg aaagattgct
    45661 taaaaggcaa taagcgttat tctggttggg ctgaatggtc agttcctgag atggttaaga
    45721 ttaacgatgt atcttcctgg tatatttcca acccatctat gggattccac ctcaacgaga
    45781 ggaaaatcga agctgaatta ggtgaagatg agattgatca caacatccaa cgcttaggtt
    45841 attggccatc ctttaaccaa aaatcagtta tatccgaaaa agaatgggca aaactcaaag
    45901 ttgagcaagt gccagaactc aaaagcaagc tttttgtcgg tatcaagttt ggtcaagatg
    45961 gcaacaacgt atcactatca attgcagcaa gaacatcaga aaataaggta tttgtcgaga
    46021 ctattgactg tttatcagtt aggaatggta ctcaatggat tattaatttt ctgaaatcag
    46081 ctgacattgc taaggttgta attgatggcg ccagcggcca agaattactt gctcaggaga
    46141 tgaaagagca aggtctaaag aaaccagaat tgcctaaagt tgctgaaatt atcacagcta
    46201 acatgatgtg ggagcagggg atcatgcagg aaaccatttg tcatagtgat cagccatctt
    46261 tgacagcagt agtcacaaac tgtgaaaaga ggcaaattgg ctctaatggt ggttttgggt
    46321 ataagtcgct ttatgatgat agagacatta gcttaatgga cagtgcattg cttgcgcact
    46381 ggatttgtta cacaacgaag ccaaaaagaa agcaaagaac cagctgttaa aaaacgacat
    46441 ccgaaagggt gtttttttac tgctaaaaaa tctaccgaac tgccgggaaa gcaggagaaa
    46501 ggacgttaat atgtcagaat ttaaagttat tgaaacacaa gaagagttgg acacgattgt
    46561 gaaagctcgc attgctcgag aacgtgagaa atatcaagat tacgaccaac tgaaaactcg
    46621 tgttgaagaa ctagaaaccg aaaacagcag cttacaaact gctttgaatg atgctaaatc
    46681 aaacactgat agctatacgg aagagattag caccctgaag aatcaaattg ccgattatga
    46741 gacggcaaat ttacggacaa aggtagcgtt acagtatggc ttaccaattg atttagctga
    46801 tcgtttgcaa ggagatgatg aagatggact caaagtagat gcagaacgct tagcatcctt
    46861 tattaagcca tcccaaccac aaccgccagc aaaatcaaac gaaccaaata tcgatagtaa
    46921 tgcagacgca aattacagag cgttagtgca aggattaagt acagaagatt agaagattaa
    46981 ttaaaggaga aaaaatatgg gaacagaaac atcaaaagca agcttatttg acaaacattt
    47041 agtatcagat cttatcaata aagttaaggg gcatagctca ctagctaaac tatctagcca
    47101 aaaacctatt ccgtttaacg gatctaaaga atttacgttt acattagatt ctgatattga
    47161 tgtggttgct gaaaacggta aaaaaacaca cggtggctta tcgctagagc ctgttactat
    47221 cgtaccaatc aaggttgagt atggtgctcg tctttctgat gaatttttat atgcaacaga
    47281 agaagaaaag attgatattt tgaaagcttt taacgaaggg tttgcgaaaa aactcgctcg
    47341 tggtattgac ctaatggcga tgcatggtat caatccacgt acaaaaaaag cgtctgacgt
    47401 tatcggcacg aatcactttg atagtaaagt gacgcaagtg gttaaattta cagagagcga
    47461 agacgctgat gcaaatatcg aagcagctgt taatctaatt cagggggctg aaggtgtagt
    47521 gacagggctt gcgatggata cagagttttc aacagcactg gcgaaagtta ccaatgggga
    47581 gatggggcct aaaatgtacc ctgaacttgc ttggggagcg aatccagata gcatcaatgg
    47641 cttgaaatcg tccgtcaata ctactgttgg tgctggagct gatgaagcag aatccaaaga
    47701 tttagtaatt attggcgatt ttgaaagcat gtttaagtgg ggttatgcaa aacaaattcc
    47761 aatggaaatc attaaatacg gtgatcctga taattcgggg aaagacctta aagggtataa
    47821 ccaaatttac ttacgtgctg aggcgtatat cggctggggt attttggacg ctaagagctt
    47881 tgctcgtgtc actaaaggag aagtataatg ttatacgtta acagtaagac tggagctagt
    47941 ttttatagct ccgtccctgt ttgtggtgga gattggactt tggttgaaca gcagacaggc
    48001 gaaaaagcaa aaacagtagc agaaattaaa cgtcagttag atgctgctgg gataaaatat
    48061 agctctaaag ctaagaaacc tgaattagag gcactcttgc ctggttagga ggtaaaagtg
    48121 ggcaattttg caacaacaga tgacgtcatt ttgttatggc gtcccttatc tgttgacgaa
    48181 ttgaaacgtg caaatgcact cttgaaagtc gtatcagata cattaagaat ggaagctgac
    48241 aaagttggca aagacttaga taaaacgatg gttgataagc cttattttgt taatgttatt
    48301 aaatcggtta cggttgacat tgtagctaga acactcatga catctactca aggtgaaccg
    48361 atgtcgcaag aaagtcaatc ggcacttggc tacacttggt ctggaactta tttggttcca
    48421 ggagggggac tgtttataaa agacaatgag cttaaacggc ttggtctaaa aaagcagagg
    48481 tatggaggta ttgagcttta tggggaaatt aagagggata acgattactt tgatagataa
    48541 agtaactatc gatatagacc ctttcggaaa tccaataaaa aaagataaag aaatatctgt
    48601 cgataatgtc cttgtatcgc cagcaacaag cgatgacata acaagccagc ttagcctttc
    48661 aggaaaaaaa gctgtttaca ctttagctat tccaaaagga gacaaccacg attggggaga
    48721 taaggaagtt agattctttg gagaaaagtg gcgcactgtc ggcctagctc ttgaaggtat
    48781 tgaagagctt attccgcttg aatggaataa gaaagttatg gtggaaagat atgagtaagt
    48841 ttaaattcaa gctcaataaa gctggtgttg ctgaattgat gaaatcatca gaaatgcagc
    48901 aggtattaac cactaaggcc acagccatca gagaacgttg tggtgatggt tacgcccaag
    48961 atatccatgt cgggaaaaat agggctaatg ctatggtcag tgctaaaacc ataaaggcca
    49021 agaaagataa ttcaaaaaac aacacattgt tgaaggcggt gcgatgattg attgaagtaa
    49081 ttatcaaaaa atatttagac gagcacttag atgtgccgtc tttttttgaa catcaaaaag
    49141 atgaacctgc acgattcatc atcttagaaa agactagcgg ggctaagcaa aatcatttgc
    49201 taagttccac gtttgctttt caaagttatg ccgaatcgtt gtatgaggcg gctttactta
    49261 atgacaaagt aaagcaagta attgagcagc ttgatgtctt gccacaagtt tctggtgtac
    49321 atcttaacgc tgactacaat tttacagata cagcaactaa gcgttatcga tatcaagctg
    49381 tatttgacat taatcactat taacaaaagg agataataat ggcaaatgat actaaaaatg
    49441 taacatctgc aaagccaaaa gcaggcggag ctatttattc tgcaccgttg gggacaacat
    49501 tgcccgagga tgcaaaatca aaattagata ctaaatttaa gaatttgggt tatgtatccg
    49561 aggatggtgt ggtcaatgaa gatacacgct catctgaaaa tattaaagcg tggggtggag
    49621 atattgttgg atctgtgcag acagaaaaag aggataaatt tacttataag ctgattgaat
    49681 cactaaatgt agaagtctta aaagaagttt atggcgctgc caatgttact ggagatttag
    49741 ataagggaat ccatattaaa tcaaattcaa aagaacttga agctcatgct atcgttattg
    49801 atatgatcat gaatggtgga attctgaagc gcatagtttt accgaatgca aaagtcgatg
    49861 aggtaggtga aattaagtat gttgacggcg aagttgtcgg atacgaaaca acactaaaat
    49921 gttttccaga tgaaaaagga gatactcatc atgagtatat tgtaaaacct ggagaagcta
    49981 ataaaaaaga aaacagcttt gaaatgtaaa ggggagtaaa tggaaatctt aaaaggaaaa
    50041 acaacatcag gatttgaata cgaaatccct aaaaaacgat taaaaaactt tgaacttgtt
    50101 gaagctattg cagaagagga aaccgatcca acagcagtgg ttaaaatcgt taatttgtta
    50161 cttggtgatg ctgctaagtc tctaaaagaa catgtacgag atgcagaagg tatcgtagac
    50221 gttgaagcta tcggagtaga aatcaaagaa atttttgaaa gtcaaaaaga tttaaaaaac
    50281 tagcaatcct cgctcagatg atagcaaaag atgatgatgc attgacttgt gatttagctg
    50341 aaacatacgg catatatgat tacagacagc tacctgctta tcaggtggct gtttttgctg
    50401 tcggtttgag atctaactct aggataaaaa tggcattatc tggagagact gaggctttgg
    50461 atactgtttt gttagctggt atttacgata atactaattt gctgttttgg tctaaaacta
    50521 aggatggtca atctggtcaa aacaaaccta aatccgtggt ggaagctata tctggatcta
    50581 aatcacaaaa agctaatgat gtcatttctt ttgcgtctgg cgaggatttt gaaaatgcac
    50641 gtaaacaatt actaggaggt gatggctaat ggcaacagaa cttggtcaag cgtatgtgca
    50701 aattatgcca tccgctcgtg gaataagtgg agcaatctca aagcaacttg atccagaagc
    50761 aaggtcggct ggtttgagcg caggtaaatt gtttggtagt aaattgaaat tagcggctct
    50821 agcggctact gctggtttag gtattttact caagaaaaca atttctgcat ctttgtccac
    50881 tggtgctgac ttacagcaat cttttggtgg tattgatacc ttgtataagg gcgctgagac
    50941 tgctgtcaaa gggtttgcta aagaagcgta caaagctggt atatcagcaa atacttatgc
    51001 agagcaagca gtttcaatgg gtgcatctct aaagcaatca cttggaggtg atgctgtcgc
    51061 ggctgccaag gctgctaaca tggcaatcat ggatatggcc gacaactcgg ctaagatggg
    51121 tactgatatc acatcaatcc aaatggctta ccagggattt gctaagcaaa actatacaat
    51181 gcttgataac ctaagacttg ggtacggcgg cacaaaagaa gagatgaagc gtcttttatc
    51241 agacgctgaa aagttacctg ccgctatggg caagaagttt gatttgagta attatgctga
    51301 tgtggttgag gctatacact tggtacagga taacatgggt atcgctggag ttgctgctga
    51361 agaagcaaaa actacatttt caggctcact agctgctatg aagtcctctt ttacaaatgt
    51421 actggcaggt ttatcactag gagatgatat aagacctgct ttacgaggac tggctgaaac
    51481 aacttctaat ttcttatttg gtaactttat tccgatggtg gcaaatatct ttaaaggatt
    51541 accatcggca attggtactt ttattggagc agcaactcct attattgcca gtcaatttaa
    51601 agggctaatg agtagccttg ggattagtat tgatttaagt cctattactg ctaaatttgc
    51661 acagattggc caaaatttac aacctgtttt taacggttta aaaacggctt ttagtcagtt
    51721 gccatcattt tttactagca ttggtagtgc agttgcacca gtaatagaca ctattattag
    51781 cggattagcc agattagatt tcagtggttt tgaggcttta atttcagcaa tcttaccagc
    51841 aattcaaaca gggttccaaa cgttcatgtc tattgtaggt ccagcgatta gtcagcttgt
    51901 aaatagtttt gttaatcttt ggaatgcttg ccaacctcta gtaacaatat taagtggcgc
    51961 attgatgcca gcttttcaaa ttttaggagc ttttctcggc ggagtcttac aaggaatcct
    52021 tggcagtatt agctttgcat ttgatgcttt aaaagttgtt attgagtttt taacgccaat
    52081 tattgattgg cttgtacaag gttttaatgc tatttcaccg gcattacaaa tcgttgccca
    52141 gtgggttggt aatgtcattg gtatatttac tagcttaggt gcatctgggc aaggtttaag
    52201 tagtatgcta agcagtgctt gggggaacat ccaaacagta gtttcgacag ctaaaaatat
    52261 gataactttg gcgattgatg gtattaaatt ggtatttagc aatctaggga atgctggaaa
    52321 tattttaaaa ggattacttt cggcagcgtg gtcagctatg caaaatgcag tagtgatagc
    52381 taaaggtatt atcaacagtg cgataagcgc tataaaaaca gcatttagca gctttggtaa
    52441 tcttgtatct agcgtaagtg gaactataaa atctgttatt ggcagtttaa aaaatgcgtt
    52501 ttacagttta gcaagtattg acttagttgg tgcaggacgt gcaatcatgc aaggatttct
    52561 aaatggacta aaatcgatgt ggggggcaat caccggcttt gttgggggta ttgctgactg
    52621 gatccgtaag cacaaagggc ctatctcata cgatagggtt ttgctaaaac ccgcaggtaa
    52681 agtaatcatg caagggttca acaatagctt gatggatggc tttaaagagg ttaaatcaaa
    52741 tgtatctggc atggctgacg atcttgcagg caccataaca ggtaaaagtc tatctctcgg
    52801 tatcgatgct aaaccaagcg tcacagctga tgacttacta tcaagcaata ttagtactaa
    52861 aactacagtc ggttctgcta caagtgactt gtcattattt tttgttaagg tgcttgctct
    52921 gttgcaagat atccttgata aaaatacgga tgtctatcta gacaaagaaa aagtcagcgc
    52981 tattttatac gaagaatttg ccaaaatcat ggctagagag gggattgcat gataccaaag
    53041 gttattattg atggttttga tacctctaca atccctaatt gtgtcctaac tggttatgat
    53101 gtaggggatg ttttatcccc tcattttgtc gaaaatgaag tgtatgggat gaatggtact
    53161 agtaggggat tagagtcata caatgagtcg aaacccactc taacatggca tttgagcact
    53221 tttgatgatg cagttaattt agtgaatcat ttagacggac ttgggaaaat cattgaattt
    53281 tggcatattc cgaagtcatt ttattattat gattgcctat ctgtcaaaat caatgcggta
    53341 actatgaact cgtggagagt cacacttaaa cttgcactat atccatttag gtatgcgaaa
    53401 ggtatctcag atgtaacgat tgcaggcaat ggaagtataa ataatccagg aaatgttttt
    53461 agtgaaccta agataattgt tgagggtacc ggcaaaggaa cactaaccat tgacaaacag
    53521 gtcatggaat taaatttgtc aggtaaagca acgattgagt gcaaacatgg ccaacaatgc
    53581 gtttatgatg gtgaaggtaa tgtgaaaaac tcaatccgaa taagaggaag attttttgaa
    53641 atacaacctg gcacacaagg tattgccgta agcggaggca ttgccaggtt aacaattagt
    53701 ccaaggtgga ggtacaaggt ttgatatcga ttaaagatga taatacacct cttgtagcag
    53761 cctttgaaga tgagattaca caggaagcga atagcgatta taaattaagt tttaagtatc
    53821 cagctaaaca tgagtatcgc cccttgatca aaaaaggaat aatcctagaa gctgatgacc
    53881 tacatggaac tcagcttttt agggtttttg agattactaa gcgacatggc tatatcaatg
    53941 tttatggtaa tcaggtcgcc gatgatttaa atggctatgc aattgactct atcagtgttg
    54001 atagggtgca aggtatgaca gtaatgtcag agttagcagg taatatcaag cgtgagcatc
    54061 cttttagctt ttttagtgat attgacggtc gtcacacatt taatcaatca gacgtatctg
    54121 ttatggacgc tttagctaat ggcaagcact caatcatggg gcagtggggt ggcgagcttg
    54181 tacgtgataa gtatcaggtt aatttgctca aaaaagctgg taaagacact gagaccttat
    54241 ttatgtataa gaaaaacctc aaatcttatg aggagacaga tactataaaa ggtctcatct
    54301 cgatactgca tctcgttgca gaagttgagg agcagcggga agaggaatct agagaagttt
    54361 ctgatgcaga cattggccac aatgaagtta gcaaaaagaa aacgattagg gtaactgttg
    54421 agagcaagct caaagacact catccgataa ttgttgaaaa gactatcaag gtgcaggatc
    54481 aagatgtcaa aacagaagag gacttgcttg catatggtaa gaaatacttt gaaaaaactc
    54541 tttgcgacat accaggtaat agtttaaaaa ttgatgttac taataactac gagggcgctg
    54601 ttaggctatt tgacacagca attgtcttcc acgagctcta tgacagagac ttacgaatgc
    54661 aaatcactgg ctatcggttc gcccctatgg ccaatcggtt aaaatccatc atctttggag
    54721 agattaagac caacttagca aaacaaatta gcaatcaaat tgacaataag gtagctgaat
    54781 caactgctca acatgacgca gcatttgaag caaaattaca aaagcagatt gataatgcta
    54841 atcgtatttt tgacacaaaa gaagctaaac tccgtgaaga gattgaagat ggcatcaaaa
    54901 aagctgaagc taatgcagag gtcaaagttg ctgaggttaa cgctaaagtg ctggaagctg
    54961 aggagctagc caaggcagtc gatgagcgac tcaaaaaatt tttatctgat gctgacacta
    55021 aagagcaaga ttttgataaa aaacttgaag aatttagaac gtctcttaaa gaccttgaag
    55081 ttgatgaaaa gcagattgat gatgctttgg ccaaagccgg ttttagcaag gatagcttag
    55141 ctgacattaa agctaaactg gaagacacgt ctgaaactgc cacagttaca gctaacattg
    55201 ttggatcaac tggcggcacg ttttacaatc gcaacagact ggatggtgat actgacaaag
    55261 ttatcacttt tgaacaaggt tatattgaca ttgcccataa tggtgaaggt tttgaagaag
    55321 gcaagacata cactatcagc tttgaggcaa cctgcgagct actgcgtaaa gtaggaatca
    55381 cagtgacaca ggctaacatg aaaggtgctc gcttagtgtt aacacctaaa aatcccaaat
    55441 tagttgtcga gagttttggc ttgactaagg atactgagac tatcaatgtc tatccgttta
    55501 gctacacagt gcttgtaacc agcgactggt ataaatctaa gcaaatagat ttaaacgcgt
    55561 cggaggtgca ggaattggcc cttgagatgg cttataaaga tgtggttgac ggtaataatg
    55621 ccacgatagc agggcagtgg tcagacagcc cgcaaatgat tttagatgga ggtagttaat
    55681 gactgaaaat ataccattaa gagtccaatt taagcgcatg agcgctgatg agtgggctcg
    55741 tagtgatgtc atcttgcttg agggtgagat aggttttgag actgatacag gctatgctaa
    55801 atttggtaat gggaaaagca agtttagcgc actcaaatac cttaccggac caaaaggtcc
    55861 taaaggagac actggtttcc aaggtaaaac tggaggaact ggtcctcggg gccctgctgg
    55921 caagcctgga acgacagatt ataatcaact ccaaaataaa ccaaatctag atgcgtttgc
    55981 acgaaaacaa gaaactgata gtaaaatcac cgaattaaaa tcaaataaag cagataaaaa
    56041 cgctgtttac ttaaaagcag agtcaaatgc aaagctagac gaaaaattga gtttgacagg
    56101 cggcatagtg acaggacaac tacagtttaa acctaatagt ggtattaaac cctcatcttc
    56161 cgtaggagga gcgattaaca ttgatatgtc taaatcggaa ggtgctgcta tggtgatgta
    56221 tacaaataaa gatactactg atggaccatt gatgatttta cgttctgaca aagatacgtt
    56281 tgatcagtca gctcaatttg tggattacag cggtaagact aatgctgtaa atattgtaat
    56341 gcgccagcca agcgcaccta atttttcctc ggcacttaat ataaccagtg ccaacgaagg
    56401 cggtagtgcg atgcaaatta gaggcgtcga aaaagcgcta ggaacgctaa aaattactca
    56461 cgaaaaccca aacgttaagg caaattacga tgaaaacgct gcagcgttat ccattgatat
    56521 tgtcaaaaag acaaacggtg aaggaacagc cgctcaagga atctacatca attcctccac
    56581 aggaacaact ggtaaaatgc tcagaatcag aaataaaaat gaagacaaat tttatgtagg
    56641 tccagatggc ggctttcact caggtgcaaa ttcaactgta gctggtaatc taacagttaa
    56701 agatccaaca tctggaaaac atgctgcgac taaagattac gtagatgaaa aaattgctga
    56761 gttaaaaaaa ctcatactaa aaaaatagat taaggaggat aaatgagcag agacccaaca
    56821 tatacaataa acgagcacga cttatctttt gcagatggtc gtttttatgt gacctttaag
    56881 gcagataagt caagtgagac tgtgagactt aacagtagtt gccttggcaa taccataatc
    56941 aaaaagctac aggtcgagga tgacaataca atgcacgact ttgtaaagcc taaagttacc
    57001 actcaacaag cttttggact agctcagcag gtcaaagagc ttgatttaca gctaaaagac
    57061 cctaagtcag atttgtgggg caaaatcaag ttcaataata aggcaatgct agtcgagtac
    57121 gccaacaaag agatgtcaag tgccattgcg caatcagctg agcagatatt gttacaagtc
    57181 aaatctattg atgatgaacg atattccaaa tttgagcaaa ctctgaatgg tatcaaacaa
    57241 actgtcaaaa gtgagtcagt tgaatccgca cgtactcagc tagcatcaat gtttgatagt
    57301 cgtattagtg gacttgatgg caaatacagt cgtttaagcc aaacaattga tagtcttagc
    57361 agtcgtcttg atgatggtgt tggtaactac tcaacgctat ctcaaaaggt aagtggcatt
    57421 gatttacgag ttagtaatgc agctaatgat gtttctcgat tgtctcagac agcacaagga
    57481 ttgcagtcac aaatcacaaa tgcaaaccaa aattacagca gtttgtctca gactgtacag
    57541 ggactacaaa caactgtacg tgataatcaa tcaaatgcta caagtcggat taatcagtta
    57601 agtgacctga tcagcacaaa ggtatcaaaa ggtgatgttg agacaactat tgctcagagt
    57661 tacgacaaga tagccttcgc aatcagggat aaactcccag caagcaaaat gtctggcagt
    57721 gagattatct cggcaatcaa tcttgatagg tctggggtta aaatcactgg aaaaaatatc
    57781 actcttgatg gtaacagcta catcagcaac gctgtcatca aagatgctca tattgctaac
    57841 atggatgccg gtaagattaa tactggttat cttaatgcta ataggattgc aaccgaggcc
    57901 attactggtg agaaaattaa gatggactat gcctttttta ataaactcac tgctaacgag
    57961 ggatatttta ggacgttgtt tgccaaagac atctttgcaa catcagtcca atctgtaaca
    58021 ctatcagcta gcaaaattac tggaggtgta ttagccgcta caaatggggc aagtcagtgg
    58081 gacctaaata atgccaatat gacctttaat cgagatgcca caattaattt taatagcaaa
    58141 aacaatgcct tagtacgtaa agatggcaca catactgcct ttgtacattt tagtaatgcg
    58201 acgccaaaag gctatagagg ctcagcgttg tatgcgtcaa tcgggataac ctcatcagga
    58261 gatggcatcg acagcgcttc gtctggacgt ttctgtggag ttaggttttt ccggtacgc
//
LOCUS       DAUCXI010000006        55730 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.006, whole genome shotgun sequence.
ACCESSION   DAUCXI010000006 DAUCXI010000000
VERSION     DAUCXI010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55730
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.006"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            452..769
                     /locus_tag="VGY43_000361"
     CDS             452..769
                     /locus_tag="VGY43_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEQ4301582.1"
                     /translation="MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRAKVNQLAFMVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSIN
                     WIK"
     gene            893..2791
                     /gene="mnmG"
                     /locus_tag="VGY43_000362"
     CDS             893..2791
                     /gene="mnmG"
                     /locus_tag="VGY43_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEQ4301583.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGYVAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            2881..4857
                     /locus_tag="VGY43_000363"
     CDS             2881..4857
                     /locus_tag="VGY43_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEQ4301584.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYQLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKHLLLKTINMTMKETGEVES"
     gene            4854..5306
                     /gene="rplI"
                     /locus_tag="VGY43_000364"
     CDS             4854..5306
                     /gene="rplI"
                     /locus_tag="VGY43_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEQ4301585.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA"
     gene            5336..6703
                     /gene="dnaB"
                     /locus_tag="VGY43_000365"
     CDS             5336..6703
                     /gene="dnaB"
                     /locus_tag="VGY43_000365"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEQ4301586.1"
                     /translation="MRLPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDD
                     FYKYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSA
                     NAEYYAKIVAEKAMLRDIIARLTESVNLAYDEILKPEEVIAGVERALIELNEHSNRSG
                     FRKISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGK
                     TAFVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWN
                     NVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKP
                     ENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDA
                     DIVAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIA
                     QFEER"
     gene            6720..6992
                     /locus_tag="VGY43_000366"
     CDS             6720..6992
                     /locus_tag="VGY43_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEQ4301587.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            7724..8335
                     /gene="rpsD"
                     /locus_tag="VGY43_000367"
     CDS             7724..8335
                     /gene="rpsD"
                     /locus_tag="VGY43_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEQ4301588.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(8489..9022)
                     /locus_tag="VGY43_000368"
     CDS             complement(8489..9022)
                     /locus_tag="VGY43_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ4301589.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFRTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
     gene            9157..11430
                     /locus_tag="VGY43_000369"
     CDS             9157..11430
                     /locus_tag="VGY43_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEQ4301590.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGDDMVDKMSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNPEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLAALTGASQQFQQST
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNTELSTLQPPNLNADELGNSLGAIAQAAKQVIV
                     EETAAQNEELSALQATSVYQSLTAEQQGELAAALSQSDKSQTVSAAQTILSSVQTLST
                     SLQSLSQEDQSKQLEQLKEAVAQIANQSNQALPGASSALTELSTGLAKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTAIGSGVIKLSEGTNALSSKSGELLDGSHQLSEGATKLADG
                     SSQLSQGGHQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWDWAKQKFVINGFI
                     STMGSIVLYLAIQLLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            complement(11546..12619)
                     /locus_tag="VGY43_000370"
     CDS             complement(11546..12619)
                     /locus_tag="VGY43_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEQ4301591.1"
                     /translation="MKNISRKCFMTSVVCIILGGILLGAGYATGGLQDIKHQTAPKKV
                     IKTFDQITALDIDSSASTITVETGPVQRPTVTYYTHPKFIDPLEIKIENETLHISEKP
                     RDVIITGGMELIGFGLNKSDRNHNYRTTTITLPKGTSLKELKGSSMPQATISDLTIQD
                     LEFSGGLTLLNTRIKKGKVFGTFDATDSLLANLELKADYSLSSLTNSSLENGTISLGH
                     GQLTTKNTNLKSVTIQSLSPGGVEAEETSLENVTFTVTSEQENEETNDNGAIFTAHAL
                     TLKGTNTISGGDVAVDITLTNPKTTAYKTKTEDGKISLGSQLTPAKIGKESTSDVISY
                     VAENKAATGNLTVNLNKGDITIK"
     gene            complement(12616..13203)
                     /locus_tag="VGY43_000371"
     CDS             complement(12616..13203)
                     /locus_tag="VGY43_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEQ4301592.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEAMEYYIEYFDEAGPDKESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIACLMLGLTAIFAAYIFGIAGILVAGVTLFESLTLIGSSIPAQAIGIGSALLCFG
                     GGLLIWIIATAILRFSGRAFVAFIKWISNKKGAQA"
     gene            complement(13190..13516)
                     /locus_tag="VGY43_000372"
     CDS             complement(13190..13516)
                     /locus_tag="VGY43_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEQ4301593.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLQKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
     gene            13721..14362
                     /locus_tag="VGY43_000373"
                     /pseudo
     CDS             13721..14362
                     /locus_tag="VGY43_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
     gene            complement(14409..15251)
                     /locus_tag="VGY43_000374"
     CDS             complement(14409..15251)
                     /locus_tag="VGY43_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEQ4301594.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     MRDNFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVIVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKVDWLWLVLTFVTSGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMTFVLFALGIWLGLWMSQLE
                     EKYK"
     gene            15654..15698
                     /locus_tag="VGY43_000375"
                     /pseudo
     CDS             15654..15698
                     /locus_tag="VGY43_000375"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15705..15986
                     /locus_tag="VGY43_000376"
     CDS             15705..15986
                     /locus_tag="VGY43_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ4301595.1"
                     /translation="MLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGT
                     LLIAISIYPIMSWLGWWGYGPVAILWLIIMRIALRIERFKKTYDVQTYR"
     gene            complement(16462..17064)
                     /locus_tag="VGY43_000377"
     CDS             complement(16462..17064)
                     /locus_tag="VGY43_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301596.1"
                     /translation="MTTKTYFMRSFNLILYLLLIAPICYVFGWLFNLVSVQLSTVTFV
                     NLDTVKNVTDTISSVCYGFALISLLLALLSGLKMIQRLNTDSLGNYCQSIYRTFLLRH
                     FLFQRERVQKVSNFEHQTVTTINPIHNGFNRAVRKCIVDIRKDAITVFLKVPRDQQGQ
                     KILKDTGVQLKEEIVIQHTDYYFSSPVRVRNQLWFIGQKR"
     gene            complement(17061..17813)
                     /locus_tag="VGY43_000378"
     CDS             complement(17061..17813)
                     /locus_tag="VGY43_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ4301597.1"
                     /translation="MAIPDLDKFSSSLQQGKIPVIKHFELNLDKGSHWAIAGNSGSGK
                     PYALTYFLSVLKPMSGLIIIDPKFDTPSQWARENKIAVIHPVENHSKSDFVSQVNEQL
                     NQCATLIQKRQAILYDNPNHQFTHLTIVIDEVLALSEGVNKNIKEAFFSLLSQIALLG
                     HATKIHLFLGSQRFDHNTIPISVREQLNVLLQIGNINQKTTQFLFPDLDPEGIVIPTG
                     HGTGIIQVVDNEHSYQVLPLLCPTYYTKRGIL"
     gene            complement(17879..18652)
                     /locus_tag="VGY43_000379"
     CDS             complement(17879..18652)
                     /locus_tag="VGY43_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301598.1"
                     /translation="MLYLNTQTDSDYKEIIFGDIAKFVENMFYHYFSSILFRDLETVD
                     KRMYSFSDDDLISIQSSCLRLSKTFANFNIQRKNFLASDETEMDTFHKKDDIDITVGE
                     KSYNLARSFRTSTINELTVFNFEEMFDIIWLMLGDNLIKSFEVNVCGILFELNGNGIP
                     STFRQENIDPLINKWWYDNVSTEIIPNLIKKLKENPLFNIGFLVDDILERMYKENIPK
                     SYLTSVPLVISKKARSTLSIKSNGSQKIDKSKFAQILSL"
     gene            complement(18853..19191)
                     /gene="cadX"
                     /locus_tag="VGY43_000380"
     CDS             complement(18853..19191)
                     /gene="cadX"
                     /locus_tag="VGY43_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HEQ4301599.1"
                     /translation="MKKDSICQVGVINQQNVTTATNYLEKEKVQKSLRILSKFTDNKQ
                     INIIFYLLAVEELCVCDIACLLNLSMASASHHLRKLSNQNILDTRREGKIIYYFIKDE
                     EIRDFFNQLG"
     gene            complement(19203..19817)
                     /locus_tag="VGY43_000381"
     CDS             complement(19203..19817)
                     /locus_tag="VGY43_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEQ4301600.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKEGLSK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGETLEKYSRWFIAVVYLGLGMYILIENNSFDMLWAVLG"
     gene            complement(20110..20259)
                     /gene="rpmG"
                     /locus_tag="VGY43_000382"
     CDS             complement(20110..20259)
                     /gene="rpmG"
                     /locus_tag="VGY43_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ4301601.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            complement(20275..20457)
                     /gene="rpmF"
                     /locus_tag="VGY43_000383"
     CDS             complement(20275..20457)
                     /gene="rpmF"
                     /locus_tag="VGY43_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEQ4301602.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            20677..21957
                     /locus_tag="VGY43_000384"
     CDS             20677..21957
                     /locus_tag="VGY43_000384"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEQ4301603.1"
                     /translation="MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRAAYRQALIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKDMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGITLPIETEMDIYLA
                     VLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFENISEQLLS"
     gene            22295..24043
                     /gene="aspS"
                     /locus_tag="VGY43_000385"
     CDS             22295..24043
                     /gene="aspS"
                     /locus_tag="VGY43_000385"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEQ4301604.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFEMLLQDLTVTVKGIDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPAAKFLTAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            24036..24977
                     /locus_tag="VGY43_000386"
     CDS             24036..24977
                     /locus_tag="VGY43_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ4301605.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDIPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIITSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            24997..25875
                     /locus_tag="VGY43_000387"
     CDS             24997..25875
                     /locus_tag="VGY43_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ4301606.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRAMVYTVTGILSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGITGGLGGGLVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     DELGRGVTYLTGEGAYSGRRKKVIYVALGRRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            25918..26790
                     /locus_tag="VGY43_000388"
     CDS             25918..26790
                     /locus_tag="VGY43_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ4301607.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(26817..27125)
                     /locus_tag="VGY43_000389"
     CDS             complement(26817..27125)
                     /locus_tag="VGY43_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEQ4301608.1"
                     /translation="MPSEKEILDALSKVYSEPVIQTDDYFRQAIFELASQLEKERMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKACHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(27213..28904)
                     /locus_tag="VGY43_000390"
     CDS             complement(27213..28904)
                     /locus_tag="VGY43_000390"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEQ4301609.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKTKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLANIFAKMGYQPVKINHLGD
                     WGKQFGMLIVAYKKWGEEAAVQAHPIDELLKLYVRINAEAEIDPTVDEEAREWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLELLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCCATATVLKEALRLLGVDAPNEM"
     gene            29195..29632
                     /gene="argR"
                     /locus_tag="VGY43_000391"
     CDS             29195..29632
                     /gene="argR"
                     /locus_tag="VGY43_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEQ4301610.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            29629..29981
                     /locus_tag="VGY43_000392"
                     /pseudo
     CDS             29629..29981
                     /locus_tag="VGY43_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
     gene            29968..32523
                     /gene="mutS"
                     /locus_tag="VGY43_000393"
     CDS             29968..32523
                     /gene="mutS"
                     /locus_tag="VGY43_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEQ4301611.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFNSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRTGFDERLDYYRKVMREGTGWIADIEAKERQESGINNL
                     KIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIISVPS
                     QVESSSAVRQGQLSLFGDEEKTHEIRQALEAIDVMNMTPLQAMTTLYELKKLL"
     gene            complement(32919..33572)
                     /locus_tag="VGY43_000394"
     CDS             complement(32919..33572)
                     /locus_tag="VGY43_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301612.1"
                     /translation="MWSSIFNFKENIVKKKLVMMLTLLISICAISVRANESGDLFTTI
                     GQSHLPGVTVAPFKTGDTTINVNLDPYGYVYGFVTSSNGNKIKKPENKTYEIPCSILE
                     KQDNRNCEGRKWTVSGNRADGGGNYTVQLEKPLAEGDKVTLSFADDGNLYFGQLVFED
                     GKTHNERLQKERDAEEQQYAEELFKRSIEEESKKTWHQRLSDSIQDQWWNFKDWLRG"
     gene            complement(33737..34120)
                     /locus_tag="VGY43_000395"
     CDS             complement(33737..34120)
                     /locus_tag="VGY43_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEQ4301613.1"
                     /translation="MSKKNAIRKLKEFHRWQRIANSLDLTYTELYQFDIEYHPTRRKH
                     LEISRECALEELDAIRYAINQLSKLDYRKILIECYLISEKKPQQDIIAELNRSQSWYY
                     ETKKRALLEFVEFYRDGVLKNNVRL"
     gene            complement(34095..34457)
                     /locus_tag="VGY43_000396"
     CDS             complement(34095..34457)
                     /locus_tag="VGY43_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEQ4301614.1"
                     /translation="MSAKEQLKELKPLFALITLFEEQRDKDIKLINAFHNPEAIRHIE
                     KGTAKQLLYLAKERDKRLAMIATLQDERQIAVIKARYVDDLSWDEILDKLGYSRNTVF
                     KLHREALEVLDEQEERYS"
     gene            complement(34860..35348)
                     /locus_tag="VGY43_000397"
     CDS             complement(34860..35348)
                     /locus_tag="VGY43_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301615.1"
                     /translation="MLELSIENIIKPMKIQGKTRVTGSIGDQAIRIDLDGLVIHYNGQ
                     GLLLETIPGTYGGKRYFFVCPYCERRCRKLFKASHAFACGSCQKVHQATLNRSKTDCC
                     YYWQLAFKECLKVNPEARHIHGYYSRDDFPKRPKYMRLTKYLYHWRRFHYYMDKGDRY
                     WL"
     gene            complement(35422..35931)
                     /locus_tag="VGY43_000398"
     CDS             complement(35422..35931)
                     /locus_tag="VGY43_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301616.1"
                     /translation="MRTFSDTPKTFTFHYTFKDFDTAQVACHAILGYMTGTYEQPVID
                     ATYHNDDQGGHANQLVLKYAEDRKLSKVFKRICDSFKDYYNQPEDMTDEELDHQRVVS
                     LSKSTQGKVNNRDTLIAFISDHNQLAEHHSMNYKEMTPEDLGAILESISQAFNHLYDM
                     VVEGQLLVK"
     gene            complement(35933..36106)
                     /locus_tag="VGY43_000399"
     CDS             complement(35933..36106)
                     /locus_tag="VGY43_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001873750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301617.1"
                     /translation="MKLKLHTRGGNTITIQGDRTLYDELTKYLLSGQQPNWVACPSAI
                     INLSDIIAITKEK"
     gene            complement(36112..36285)
                     /locus_tag="VGY43_000400"
     CDS             complement(36112..36285)
                     /locus_tag="VGY43_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2758 domain-containing protein"
                     /protein_id="HEQ4301618.1"
                     /translation="MKIKLFYQKHNESLDDFEHRVNLFTLSVSVIDIKFQEATYGNYE
                     DMDSRTGLLVLYR"
     gene            complement(36282..36536)
                     /locus_tag="VGY43_000401"
     CDS             complement(36282..36536)
                     /locus_tag="VGY43_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301619.1"
                     /translation="MNPNYTNHGVKKMRYNYDDLPNDQLYRLELPNGQCGYDFITKIN
                     FNTKSRPGDCDFTRPELTRRGYQWVFDCGFAIPVEKGAKT"
     gene            complement(36830..38223)
                     /locus_tag="VGY43_000402"
                     /pseudo
     CDS             complement(36830..38223)
                     /locus_tag="VGY43_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656427.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
     gene            complement(38235..39101)
                     /locus_tag="VGY43_000403"
     CDS             complement(38235..39101)
                     /locus_tag="VGY43_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEQ4301620.1"
                     /translation="MAIYEARGFSSYLYPYKGPLEPFDYIAQFRPLKPPEDIDIEEYK
                     RTQAPYCLSGKVTAEKNGSYKRNNASLVYRDLIFLDYDEIETGVNLPKIVSQTLWEYS
                     YIIYPTIKHTPEKPRYRLVMKPSDVMTEATYKQVVKEIADKIGLPFDLASLTWSQLQG
                     LPITTGDPEDYQRYVNRGLGYPVPKNGNTPNRQVVTTYTPRPRSQRSITMRVIDTLFN
                     GFGDEGGRNVALTKFVGLLFNKWVDCDLETAYELVQIANSVTTKPLPIDEIDTTFRSI
                     LDKELRKRGIKP"
     gene            complement(39102..39374)
                     /locus_tag="VGY43_000404"
     CDS             complement(39102..39374)
                     /locus_tag="VGY43_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301621.1"
                     /translation="MNVFSQDYESKLLEQNLTAFNRFLEAYQKPKPRVLGLITAEQVK
                     EELNIKGKTLKRWENAGLRRYQPPLEDTRKHYYKVSDILIFLGVSV"
     gene            complement(39377..39685)
                     /locus_tag="VGY43_000405"
     CDS             complement(39377..39685)
                     /locus_tag="VGY43_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301622.1"
                     /translation="MTLPENYRRVLNLIKVGAEISLILKLEERSVQSIISSLITRYNV
                     PIIGIRHGFNRGYFIPANKEELLDGAKAFYNQVQKEQERLSVLLNADLTSYKELLKGG
                     "
     gene            complement(39682..40044)
                     /locus_tag="VGY43_000406"
     CDS             complement(39682..40044)
                     /locus_tag="VGY43_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301623.1"
                     /translation="MTTEEYFKKLLEDSEKQPTNWLSDRVLDKNIKMLDEDIEAEWDD
                     FPLFTKKIFINTTQRNYNKADAVVKFLESIPIEMEYKKGLNIVIQALNELKDSLKNQV
                     LGVIDNQILFPNDKEDTK"
     gene            complement(40056..40247)
                     /locus_tag="VGY43_000407"
     CDS             complement(40056..40247)
                     /locus_tag="VGY43_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301624.1"
                     /translation="MQELNLTPTQTLILFFVLSLLGLLLSLSKSLIDIDLPEDTQVPK
                     PPKNANYGAYIQSQNHYYN"
     gene            complement(40247..40579)
                     /locus_tag="VGY43_000408"
     CDS             complement(40247..40579)
                     /locus_tag="VGY43_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301625.1"
                     /translation="MKYRVETNPFSKDRYTPEQLEMFKNRQLSKNKAEAYFTRLYNQH
                     IAWVIIANVMTEYVIKFRKSATSFEEAWDALDYQRTTEIVFRAVNGLPCSEKDSGELE
                     TYLSEVSA"
     gene            complement(40836..41078)
                     /locus_tag="VGY43_000409"
     CDS             complement(40836..41078)
                     /locus_tag="VGY43_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor protein"
                     /protein_id="HEQ4301626.1"
                     /translation="MKATTYKELKKWIDEGVDLAELAQGYADKVPNADREQFEAITQE
                     IFNVLEGVSLMLDDKVLIYNRKAEQKRLNDIEQGNY"
     gene            complement(41105..41722)
                     /locus_tag="VGY43_000410"
     CDS             complement(41105..41722)
                     /locus_tag="VGY43_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEQ4301627.1"
                     /translation="MNKTETWNGYTIRFVEHQGEWWAVAKDITNALGLKQPSRAISTL
                     KGVTKSKTLTKGGEQELSIINEKDIYRLVFKSRKPEAEAFQEWVFETIKQLRQSTGLE
                     GFQVFRMFDKEHQKQSMNRLVNGLQNATKKDLIKANTIANKAVSNKYGLPKMISKNEM
                     TENMLRDREPILDETVELIKVKEKYGLNFSVSEAIFNQNTIKKAQ"
     gene            complement(41732..42499)
                     /locus_tag="VGY43_000411"
     CDS             complement(41732..42499)
                     /locus_tag="VGY43_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEQ4301628.1"
                     /translation="MRRNYSKVIDELRTSYNLNLVAIGQRIGIDPRTVGKWWQGKHNP
                     NQESRKKLNRLYREVKETMMTQVNIFEEANDNTKQVMQVITTTNFHGQPLDIYGDIQE
                     PLFLARAVAEMIDYTKTSQGYYDVQAMLRKVDEDEKLKGMALEGTTKNFRSGQKVWFL
                     TEHGLYEVLMRSNKPKAKEFRKAVKNILKEIRLNGYYMQGELVQELAQSSTQKLPGIS
                     DLTYIRNKLADLVDMDNLADISNGIDRVQQLVKLISL"
     gene            complement(42533..42739)
                     /locus_tag="VGY43_000412"
     CDS             complement(42533..42739)
                     /locus_tag="VGY43_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4301629.1"
                     /translation="MTQITLKAARINAGYTLKQVAGAVGKNPQTISKYEKDSSDISLG
                     LLQKLSSLYGVTIDNLFLGKKVRK"
     gene            42893..43660
                     /locus_tag="VGY43_000413"
     CDS             42893..43660
                     /locus_tag="VGY43_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ4301630.1"
                     /translation="MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTI
                     TGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSNNIETNSNIIPSTLQKVTSTLSQ
                     LEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
                     PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVIND
                     SGAFLHSLNDKYDDILIDRDSDFRIIGEVIGSFTSKS"
     gene            44051..44212
                     /locus_tag="VGY43_000414"
     CDS             44051..44212
                     /locus_tag="VGY43_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301631.1"
                     /translation="MSINKKQVFLTLCGISISVTGIDMLLSGEYLRGVIKLILAFGIF
                     VIFSKDRDE"
     gene            44473..45327
                     /gene="dinD"
                     /locus_tag="VGY43_000415"
     CDS             44473..45327
                     /gene="dinD"
                     /locus_tag="VGY43_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein D"
                     /protein_id="HEQ4301632.1"
                     /translation="MNGLQHYDELAFENIKHIDENGVEFWYARELQTVLEYAKWDNFL
                     NVIERAKIACENTGNPVAMNFPEVSKIVQLPLGDREIKDYKLSRYACYLIVQNGDPRK
                     EVIALGQSYFAIKTRQQELADNFNKLDEEHKRLAIRQEMKEHNKSLAEAAKMSGVTNY
                     GKFQNFGYKGLYGGMSMQDIHDRKELEKGQSILDYMGSAELAANLFRATQTDEVLRNR
                     QIHDENLANDTHFNVGRTIRKTMQKLGTTMPENLPTPQESIQDLKKKHKQLDKQPDDN
                     QLSLFDDM"
     gene            45585..46730
                     /locus_tag="VGY43_000416"
     CDS             45585..46730
                     /locus_tag="VGY43_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ4301633.1"
                     /translation="MKIKEHKKKNGAIVYRASIYLGIDQMTGKRVKTSITGRTQTEVK
                     QKPKHAQFDFLSNGSTIKRKVVIKTFKELSHLWLETYKLTVKPQTYDATVTRLNRHIM
                     PTLGNMKVDKITASDIQMLINRLSKYYVNYTAVRSVIRKVLQQGVLLGLIDYNPARDI
                     ILPRKQPNAKKKVKFIDPSDLKSFLEHLESSQHKRYNLYFDAVLYQLLLSTGLRIGEA
                     CALEWGDIDLENGTIAINKTYNKNLKFLSTAKTQSGNRVISVDKKTLRSLKLYQMRQR
                     QLFNEVGARVSEVVFATPTRKYFNASVRQSALATRCKEAGIERFTFHAFRHTHASLLL
                     NAGISYKELQYRLGHANISMTLDTYGHLSKDKEKEAVLYYEKAMNNL"
     gene            46825..48807
                     /gene="mutL"
                     /locus_tag="VGY43_000417"
     CDS             46825..48807
                     /gene="mutL"
                     /locus_tag="VGY43_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEQ4301634.1"
                     /translation="MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLTLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTT
                     KKMLAISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAV
                     DNSVKVEKAELLPHSEEVIGPSSVKHASRPQNIFTETDHPNLDLKNRQKLSQMLTRLE
                     NEEKSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            48818..50038
                     /locus_tag="VGY43_000418"
     CDS             48818..50038
                     /locus_tag="VGY43_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ4301635.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFAGILLVEIASSFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHGKGLLDSFRNYRQVFHDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLAFTFTQLYAIWLSVVLLTFGEMINVP
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALL
                     GIYFTVVSAKMKKV"
     gene            50040..50636
                     /gene="ruvA"
                     /locus_tag="VGY43_000419"
     CDS             50040..50636
                     /gene="ruvA"
                     /locus_tag="VGY43_000419"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEQ4301636.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL
                     LALGYKAKELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            50646..51206
                     /locus_tag="VGY43_000420"
     CDS             50646..51206
                     /locus_tag="VGY43_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEQ4301637.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVATFTSEELADALENPSIIRHKLKLAATVNNAIA
                     VQKIQEEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            51275..52546
                     /locus_tag="VGY43_000421"
     CDS             51275..52546
                     /locus_tag="VGY43_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEQ4301638.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRRDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPI
                     VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVAYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            52635..53771
                     /gene="recA"
                     /locus_tag="VGY43_000422"
     CDS             52635..53771
                     /gene="recA"
                     /locus_tag="VGY43_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEQ4301639.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPQLFD
                     EIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED"
     gene            54062..54460
                     /gene="spx"
                     /locus_tag="VGY43_000423"
     CDS             54062..54460
                     /gene="spx"
                     /locus_tag="VGY43_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEQ4301640.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
     gene            54574..54843
                     /locus_tag="VGY43_000424"
     CDS             54574..54843
                     /locus_tag="VGY43_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEQ4301641.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            54840..55259
                     /gene="ruvX"
                     /locus_tag="VGY43_000425"
     CDS             54840..55259
                     /gene="ruvX"
                     /locus_tag="VGY43_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEQ4301642.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            55271..55576
                     /locus_tag="VGY43_000426"
     CDS             55271..55576
                     /locus_tag="VGY43_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEQ4301643.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
BASE COUNT        17095 a         9716 c        11165 g        17754 t
ORIGIN      
        1 atttctagtt atacttttat ggttttgtta tcggcgttct tacttgtaga cttagaaaca
       61 acggtatctg tattttacta ctttagaaga tatcaaaaaa tcgtatgata atactgatga
      121 catttttatt tctcgcctcg ctagattaga catagtgata cttttgtaat cattttaaaa
      181 acattacaat agattgacag agctgtaaaa acattgacat tactgtaaag gtctgtgatg
      241 aaatcaatat tgacaatcac taatcatttt tttaaaatag atagtaacaa tcggaatgat
      301 ggtcaaagct catgaaagtt gtaggttttt ttgtcctgca atcttctagg gttttggccc
      361 ttttatggtt tagctctaga aatgagatgg ctaataggac tggaatttaa aatcactaga
      421 ggtcagataa ctttagttta cgagctagcg cttgattgtt agaaatggta agaatttttt
      481 aactagagat gcagctgacc aatattacac cattggtggt acaagtttgg taggtgaaaa
      541 aacgcatgaa actgttttac gtgaaacctt agaggaagtt ggtattcgag ctaaggttaa
      601 tcaactggct tttatggttg agaatcattt tgatatcgat gatgttttct ggcataatat
      661 tgaatttcat tatttggtaa gccccttaga agaccctaaa ctagaaatga tagagaatgc
      721 aagcgacagg tttgtgaatg gattccaatc aatcaactgg atcaaatgaa tcttgttcct
      781 gagtttttac aaaccgagtt ggctaaatgg ccaggacata ttgtccgcat tgaaggctaa
      841 actaaagcgt atgattttaa atgaatagac tgaaataaag gattttaaaa aaatgacaca
      901 tgaatttaca gaaagctatg acgtcattgt cataggtgca ggtcatgctg gtgttgaagc
      961 cagtttggcc actagtcgta tgggttgtaa aactttattg gcaacaatca accttgatat
     1021 gttggctttt atgccgtgta atccttctat tggaggatct gccaaaggga tagtagtacg
     1081 agaaatcgat gctcttggcg gcgaaatggg taaaaatatt gataaaacct atatccagat
     1141 gaaaatgctt aatacaggta agggaccagc tgtacgcgct ctccgagctc aagcagataa
     1201 atccctgtat gcgcgtgaga tgaaacatac ggttgaaaaa caggctaatt tgactcttcg
     1261 ccaaacgatg attgatgata ttctagttga agatggacga gttgtaggtg ttttaacagc
     1321 cacaggacaa aagtttgcag ctaaggcagt tgtagtgaca acaggaacag ctctgcgtgg
     1381 cgaaattatt ttaggagaac tcaaatattc ttctgggcct aataatagtt tggcatcagt
     1441 aaccttagca gataatttaa aaaaactcgg cttagaaatt ggcagattca aaacaggaac
     1501 gcctcctcgt gtcaaagcat cttctattaa ttacgatcaa acggaaattc agccaggtga
     1561 tgataaacct aatcattttt catttatgtc aaaagatgct gattacctca aagatcaaat
     1621 tccctgctgg ttgacttata ctaatcaaac tagtcatgat atcattaatc agaaccttta
     1681 cagagcaccg atgttttctg gcattgttaa aggtgtaggc cctcgttact gcccatctat
     1741 tgaagataag attgttcgct ttgctgataa agaacgtcat caacttttct tagagccaga
     1801 ggggcgtgat acagaagaag tgtatgttca agggttgtca acgagtcttc cagaagatgt
     1861 ccaaaaagat ttgattcatt cgatcaaagg acttgaaaag gctgaaatga tgcgcactgg
     1921 ttatgctatt gaatatgata ttgttttacc tcaccagcta cgtgccacac ttgaaaccaa
     1981 gctaatttca ggactcttta cggctgggca aactaatgga acttctgggt atgaagaggc
     2041 tgctggccaa ggacttattg ccggaatcaa tgctgctttg aaagttcaag gtaagccaga
     2101 acttattttg aaacggagcg atgcttatat tggcgttatg attgacgatt tggttaccaa
     2161 aggaaccttg gaaccttatc gattgttgac atcgcgagct gagtatcgtt tgattttacg
     2221 tcatgacaac gctgatatgc gtttgacaga gattggtcgc gacattgggt tggttgatga
     2281 tgagcgttgg aaggccttcg aaattaagaa aaaccaattt gataacgaat taaaacgtct
     2341 gaacagtatc aaattaaaac cagtaaaagc aaccaacgat cgtgtgcagg agcttggttt
     2401 taaaccattg acggatgcta tgacagctaa agaatttatg cgtcgcccag aaattgatta
     2461 tgcgactgca gtctcttttg ttggttatgt ggctgaagat ttagatgcta aaatcattga
     2521 acttttagaa acagaaatca agtacgaagg ctatattcgc aaagctttag atcaggttgc
     2581 taagatgaaa cgcatggaag aaaaacgtat tcctgcaaat attgattggg atgctattga
     2641 ttctattgca actgaggcgc gtcagaaatt taagaaaatt aatcctgaaa caattggaca
     2701 agctagtcgt atttcaggag tcaatcctgc ggacatcagt atcttgatga tttatttaga
     2761 aggaaacgga aaagctcatc gaaaatatta aatggaaatg aaattgtaat ctcaaagcaa
     2821 gtggaagctc tgtatttcag ggctttttta tggtataatg tgtgcttaag aggttataag
     2881 atgaaaaaat ttcgttttga aaccattcat ttgattatga tgggattgat tttatttgga
     2941 ctactggcac tttgtgtcag tattatgcaa tcaaaaatat taatattatt agctattttt
     3001 ctcgttttgc tatttgttgt tgctctttta tggtatcaaa aagaagctta tcaattatca
     3061 gacttagctc atattgagct cttaaatgaa caaacagaag ataacctaaa aacgctactt
     3121 gataatatgc ctgttggagt agttcaattt gatcaagaga ccaacgctgt agaatggtat
     3181 aatccttatg cagaattaat ttttacaact gaagagggtt ttatacaaaa cagtttgatt
     3241 cagcaaatta ttacggaaaa acgtcgtgaa gatatttctc aaacatttga agtttctggt
     3301 aataaataca cttcttatat tgatgtatca tcaggaattt tttatttttt tgatagcttt
     3361 gtgggaaaca ggcaattagc tgatgctagt atgttaagac cggttgttgg cattatttcg
     3421 gttgataatt atgatgatat cactgatgat ttatcagatg cagatacctc aaaaattaat
     3481 tcatttgtag ctaacttcat tgatgagttt atggagtcaa aacggatttt ttaccgtcgt
     3541 gttaatatgg atcgctacta tttctttaca gactttaaaa cattaaatga tttgatggat
     3601 aataaatttt ctgtcttaga agagtttcgt aaagaagctc aagatgctca gcgcccttta
     3661 acactcagca taggaatttc ttttggtgaa gaaaatcata gccagattgg acaggtagct
     3721 cttgagaatc ttaatattgc gcttgttcgt ggtggtgatc agattgtcat tcgtgaaaat
     3781 gcggatcata cgaatccaat ttatttcggg ggagggtctg tttctacagt taaacgttca
     3841 agaacacgta cccgtgctat gatgacagct atttcagatc gaatcaagat ggtggacaat
     3901 gtttttattg ttggacatag gaaacttgat atggatgcac taggttcagc tgttggtatg
     3961 caatttttcg caggtaacat tattgaaaat agttttgccg tttacaatcc agatgagatg
     4021 agtccagata ttgaaagggc tattgagcga ttgcaggctg acggaaagac tcgtctaatc
     4081 agtgtttctc aagcaatggg tttagtgact ccaagatcac ttttagtaat ggttgatcat
     4141 tctaagatat ctttaacact ttctaaagaa ttttatgaac agtttcaaaa tgttattgta
     4201 gttgatcatc acagaagaga tgatgatttt cctgataatg ctatcttaac ttttattgaa
     4261 agtggagcaa gtagtgctgc ggagctcgtc actgagttaa ttcaatttca aaatgctaaa
     4321 aaacgtttaa ataagatcca agccagtgtt ttaatggcag gtattatgct tgatactaaa
     4381 aatttttcta cgcgagtgac aagtcgtacc tttgatgtcg ctagttactt aagaagtaaa
     4441 ggaagtgaca gtgttgaaat tcaaaatata tccgcaacag attttgaaga atataagcaa
     4501 ataaatgaaa ttattttaca aggagaacgt cttggtgaca gtatcattgt agctgcagga
     4561 gaaaaaaatc atctttatag caatgttatt gctagtaaag ctgcagatac gatactgtca
     4621 atggctcacg ttgaggctag ctttgtatta gttgaaacag cttctcataa gattgctatt
     4681 tcagctagaa gtcgtagtaa aatcaatgtt caacgtgtga tggaaaaatt aggtggagga
     4741 ggccacttta atcttgctgc ctgtcagtta acggatatca gtcttcccca agcgaagcac
     4801 ttattattaa aaactattaa tatgacaatg aaagaaacag gagaagtaga atcatgaaag
     4861 ttattttttt agcagatgta aaaggaaaag gtaaaaaagg agaaatcaaa gaggtcccaa
     4921 caggctatgc tcaaaatttc cttattaaga aaaatttagc taaagaagca actagtcaaa
     4981 gcatcggtga attaaaagga aaacaaaaag ctgaagaaaa agctcaagct gaaatattag
     5041 cagaagctca agctgtcaag gctgttttgg atgaggacaa aacacgtgtt caatttcaag
     5101 aaaaagttgg tccagatgga cgtacatttg gttccatcac agctaaaaag atttcagaag
     5161 aattgcaaaa gcaatttggt gtaaaagttg ataaacgtca tattgtttta gatcatccta
     5221 tccgcgccat tggtctaatt gaagttcctg tgaaattaca taaggaagta acagctgaga
     5281 ttaaattggc tatcacagaa gcataatata aaaaacatca caagatttgg aggttatgag
     5341 gttgcctgaa gtagctgaat tacgagttca accccaagat ttactagcgg agcaatctgt
     5401 tcttgggtca atctttatct cacctgataa gctgattgca gtgagagaat ttatcagtcc
     5461 agacgatttt tataagtacg ctcataaaat tatctttcgg gcaatgatta ccctcagcga
     5521 tcgtaatgat gccattgatg caaccactat aagaacaatc ctagatgatc aagatgatct
     5581 gcaaagtatt ggtggcttat cctatattgt tgaactagtt aatagtgtcc caactagtgc
     5641 taatgcagaa tattatgcta aaattgtagc tgagaaagct atgttgcgtg atattattgc
     5701 taggttgaca gaatctgtca acctagctta tgatgaaatt ttaaaaccag aagaggttat
     5761 cgctggagtt gagagagctt taattgaact caatgaacat agtaatcgta gtggatttcg
     5821 caaaatttca gatgtgctaa aagttaatta cgaggcttta gaagcacgtt ctaagcagac
     5881 ttcaaatgtt acaggtttac caactggttt tagagacctt gacaagatta caacaggttt
     5941 acacccagat caattagtta ttttagctgc tcggccagca gtggggaaga ctgcctttgt
     6001 tcttaatatt gcgcaaaatg tggggactaa gcaaaaaaag actgttgcta ttttttcttt
     6061 ggaaatgggt gctgaaagtt tagtagatcg tatgcttgca gcagaaggaa tggttgattc
     6121 gcacagttta agaacagggc aactcacaga tcaggattgg aataatgtaa caattgctca
     6181 gggagctttg gcagaagcac cgatttatat tgacgatacg cccgggatta aaattactga
     6241 aatccgcgca agatcacgga aattgtctca agaagtggat ggtggtttag gtcttatcgt
     6301 aattgactac ttacagttga ttacaggaac taaacccgaa aatcgtcagc aagaggtttc
     6361 agatatttca agacagctta aaatcctagc taaagaattg aaagtaccag ttattgccct
     6421 aagtcagctt tctcgtggcg ttgagcaaag gcaagataaa cgaccagttt tatcagatat
     6481 tcgtgaatca ggatctattg agcaggatgc cgatattgta gccttcttat accgggacga
     6541 ttattaccgt aaagaaggtg atgatgctga agaagctgtt gaagataaca caattgaagt
     6601 tatcctcgag aaaaatagag ctggggcgcg tggaacagtc aaactgatgt tccaaaaaga
     6661 atacaacaaa ttctcaagta tagcccagtt tgaagaaaga taagaaagag agacaaaaaa
     6721 tgagcgatgc atttacagat gttgcaaaaa tgaaaaaaat taaagaggac ataagagccc
     6781 atgaaggaca gttagtagaa ttaacccttg agaatggacg gaaacgggaa aaaaataaaa
     6841 ttggtaggct tattgaggtt tacagttcac tctttatcat tgagtatagt gatagctctg
     6901 atactccagg agcaattgat aattcttatg tcgaatcata cacctattca gatattttga
     6961 cagaaaaaac attaattcgt tatttagatt gatttttgcc tcatagaggc tttttcttta
     7021 caataaattg atataattat tagcgataga agattattct gcctgtattc tttttatttt
     7081 gaaaaaattc ctataaaaga taatattttt aggttagatt gaggtaaaaa agaggtcttc
     7141 accatggtta agcaaatgat cttagtatta aggttaaaag attatcgtga aataaagttt
     7201 tgacacaagt gtaattaata gaggaacttg aagtatccgg taaaactatc ttgaagtgaa
     7261 aaaccgagta gacctcccct gactaaatac aatatactag ccatttcaga gcaattaaga
     7321 gtttccagtg aagtgctttt gatagagagc taagaaaaaa aacagtcaag gtttaagaac
     7381 tgcaaattag catttaaatt attttttgtt aatgacagtt gtctttatta ccataactat
     7441 aacttcttat aatatagtct tcttaattca tcagtggtgg ctcgtcccat atctgacctt
     7501 aaaatattaa actgatcatc agatgataga tagactgact ttacaaaaca actttcttat
     7561 ggtaaactgt tctttgtgcg aaataacagc agaaaaatat gaagctcgtc aacaggtggt
     7621 tatctattca agtaaccttt gctgtttagg cgaaaacccc ctgcacgaat caggattttt
     7681 taaaccgtta tttcctcaaa aaatttagag gaggacatgt aatatgtcac gttatactgg
     7741 tccatcatgg aaacaatcac gtcgccttgg tttatcactt acaggcacag gtaaagaatt
     7801 ggcacgtcgt aactacgttc ctggtcaaca cggtccaaac aaccgtagca aactctcaga
     7861 atatggtttg cagttagctg agaaacaaaa actacgtttc tcatacggtt taggtgaaaa
     7921 acaattccgt aacttgttcg ttcaagctac aaaaatcaaa gaaggaactc ttggtttcaa
     7981 ctttatggtt cttttagaac gtcgtcttga caacgttgtt taccgtctag gtttagcaac
     8041 tactcgtcgt caagcacgtc aattcgttaa ccacggtcac atccttgttg acggtaaacg
     8101 cgttgatatc ccttcatacc gcgttgatcc aggtcaagtg atttcagttc gcgaaaaatc
     8161 aatgaaagta cctgcaatcc ttgaagctgt tgaagctact cttggacgtc cagctttcgt
     8221 atcatttgat gctgaaaaac ttgaaggttc attgactcgc cttccagaac gcgatgaaat
     8281 taacccagaa atcaatgaag cacttgtcgt tgaattctat aacaaaatgc tttaatttta
     8341 agattaaact tacaaaaagc ctatttaata ggcttttttt gtatctcata acaaatctat
     8401 tctgatccct tcattttact atggcttcta aaaaagttat cactaaggct gatgacttgt
     8461 aaaatgatac tttcgtaagg gttactattt aggtactcgt aagcattttg agaacgaatt
     8521 gtgtcatttc ttgaggtgat tcttttttac ctttagcaat ccaactttga cagacaccaa
     8581 aaaaagcatg ggctaagtag atactttggt attctttttc cgtttgagat aactcttcgg
     8641 tgcggaactt gtcctgtaaa tcagtagtga tgagtaggcg aactttattg atgataaagg
     8701 cctgtatttc tttggtaccg ttagcagaca aaagggaaga gagaagctgt tctctttgga
     8761 gaaattcaaa tacttcaagg aaggcttgtt ctttattttg atactttttc tcaaaaatat
     8821 attctaattt gtgaaaaaag gtttgctgat aatagtcaat catttcatat ttatctttat
     8881 agtgtgtgta aaaactagag cgactaattc cagctctttt agataattta actgtggtaa
     8941 tatcgtcaaa actttcggtt tttagtaaca taaccattgc ttttaaaatt gcttgcttcg
     9001 tattttcttt acggttgacc atctaccatc tctccttttg aacactttta gacataatgt
     9061 ccaaaagtga aattttttat cttgtaaatt taaatttaaa ttgtataata tattttatca
     9121 taatttttga acaccatgtc cattttagga gaaaatatgt tagaagaatt gaaaacactt
     9181 attaaaaatc caaaattaat gattacaatg attggtgtgg ccctagtgcc tgccttatat
     9241 aatttatcct ttctaggctc aatgtgggat ccttatggtc gggtcaatga ccttcccatt
     9301 gctgttgtta atcatgataa gcctgcaaag agagctgata agtcattgac aattggggat
     9361 gatatggtag acaagatgtc taaaagtaaa gatttagagt atcattttgt ctcagctaag
     9421 caagctcaag agggacttaa agaaggtgat tattatatgg ttattacttt acccgaagat
     9481 ctttctcaac gggcagcaac cttattaaat cccgaacccc aaaaattaac tatccgttac
     9541 caaacgagta aaggacatgg aatggtcgct gctaagatgg gggaaacagc gatggctaag
     9601 ctgaaagagt ctgtttcgca aaacattacg aagacttata cctcagcagt ttttagcagt
     9661 atgacagacc tccaatcagg attaaaagaa gcctcagctg gaagtcaagc acttgcttca
     9721 ggagcgaaga ccgctcaggc ggggagtcaa acactttcga cgaacttagc agccttaacg
     9781 ggtgctagcc aacagtttca acaaagtact ggtcgattga catcaggttt gactacctat
     9841 acagatggtg tcaaccaagt caagaatggg ttaggaacat tatcaacgga catccccaat
     9901 tatttgaacg gggtttctag gttatcccag ggagcttctc agcttaatca gggtctttca
     9961 cagttgacac aagcaacaac actttctgac gagaaagcta agggaattca atccttaatt
    10021 gtaggactac cagtcctaaa tcaaggcatt cagcaactaa atacagagct atcaacattg
    10081 caacccccta accttaatgc tgatgagtta ggtaatagct taggagctat cgctcaagct
    10141 gccaaacaag tcattgttga agagactgcc gctcagaatg aagaattatc ggctctccaa
    10201 gctactagcg tttaccaatc attaactgct gaacaacaag gagagttagc tgcggccctc
    10261 agtcaatctg ataaaagtca gaccgtatct gcagcccaaa ctattttaag ttctgttcaa
    10321 actttgtcaa caagtttaca gtctctctct caagaagatc agtcaaaaca gttggagcaa
    10381 cttaaggaag ctgttgcaca gattgctaat caatccaatc aagctttgcc gggagcaagt
    10441 tctgctttaa ctgaattatc aacgggatta gcaaaggtaa atggtagctt aaatcaacaa
    10501 gttctaccag gaagtaatca attgacaaca ggattagcac aattaaacag gtataatact
    10561 gccattggtt ctggggtaat aaaactctca gaaggtacca atgccttgtc atccaagtcc
    10621 ggagaattac tagatggtag ccatcaatta tcagagggtg ctactaaact agctgatggt
    10681 agttctcaat tgagtcaggg tggtcatcaa ttaacgagcg gattgactga attatcaaca
    10741 ggattgtcaa ccttaaatgg ttccttagcc aaagcctctc agcagttatc gcttgtttct
    10801 gtgactgata aaaatgctaa agctgtcgca aaacctcttg tgttaaatga gaaagacaaa
    10861 gatggtgtta agacgaatgg gatcgggatg gcaccttata tgattgctgt ttctctaatg
    10921 gttgtggccc tttcaaccaa cgtcattttt gctaattctt tatctggtcg tccggtcaaa
    10981 gataaatggg attgggctaa acaaaaattt gttattaatg gttttatttc gactatggga
    11041 tccattgttc tctacttagc tattcaatta ttagggtttg aagcccgtta tggtatggaa
    11101 accttaggat ttattatgct aagtggttgg acgtttatgg ctcttgtcac agctttggtc
    11161 ggttgggatg atcgatatgg ctcttttgct tctttggtca tgttattgct tcaggttggc
    11221 tcttcaggtg gctcttaccc cattgagtta agtggagcat tcttccaaaa gttacatcct
    11281 ttcttaccaa tgacttatgt ggtatctggt ttacgacaaa ccatttcatt atcaggtcat
    11341 attggagtag aagtgaaagt cttaactggt ttcttactgg catttatggt attagcacta
    11401 ctcatttatc gtcctaagaa aacagtctaa ataaaataac ctcaaaaaaa acagcatcta
    11461 aggcagttac actagatgct gttttttgtc ttattttgac aataacttga caatttctgt
    11521 caagtttttt attgtcttgt taagatcatt tgatagtaat gtctccctta ttgagattaa
    11581 ccgttaaatt tccagtagct gctttattct cagccacata agaaataaca tctgaagttg
    11641 attccttacc aatcttagct ggtgtcagct gtgatccaag tgagatttta ccatcttcgg
    11701 tttttgtctt ataggcggtc gtctttggat tggtcaaagt tatgtcaaca gcaacatcac
    11761 caccactaat cgtattagtg cctttaaggg taagagcatg agcagtgaat atagcaccat
    11821 tatcattggt ttcctcgttt tcttgctcac tagtaacagt gaaagtcaca ttttcaaggc
    11881 ttgtttcttc ggcttcaacc ccaccaggag atagagattg gatggtgaca gatttaagat
    11941 tagtattttt tgtggttaat tgtccatgcc ctaagctaat cgtcccattt tctaaactag
    12001 aattcgtaag gcttgacaac gaatagtcgg ctttcaactc aagattggct aacaagctat
    12061 cagtagcgtc aaatgttcca aaaaccttcc ctttctttat tctagtattt agaagtgtca
    12121 gaccaccact gaattcaagg tcttgaatcg ttaaatccga tatagtggct tgaggcatgc
    12181 ttgagccttt gagctcttta agactggtac cttttggaag cgttatggta gtggttcggt
    12241 agttgtggtt gcggtcactt ttatttaatc caaacccgat cagttccata cctccggtga
    12301 tgatgacatc tctgggtttt tcagaaatat gaagtgtctc gttctctatt ttaatttcta
    12361 aaggatcaat aaatttagga tgtgtgtaat aggtcactgt tggtctttga acgggtcctg
    12421 tctctactgt aatagttgag gcagaactgt caatatcaag agcagttatt tggtcaaatg
    12481 ttttgatgac ctttttggga gctgtttggt gtttaatgtc ctgaagtcct ccagttgcat
    12541 agccagcccc tagaagaatg cctcctagaa taatacatac cacactggtc ataaagcatt
    12601 tgcgtgagat atttttcatg cttgagctcc tttcttatta ctgatccact taataaaggc
    12661 aacaaaagcc cgtcctgaaa aacgaaggat tgctgtggca ataatccaaa taagaagacc
    12721 accaccaaaa cacaacaagg cgctgccgat gcctatagct tgtgcaggaa tagatgagcc
    12781 aatcaaggtc aagctttcaa acagagtcac tcctgcgaca agaatacctg caatcccaaa
    12841 aatgtaggcg gcaaagatag ctgtgagccc gagcattagg caggcaataa taaagagaat
    12901 caacgctagc aatacgggta aagcaatcgg agcagcaaag agggacaaaa tggttaatcc
    12961 aataattgtt gcccgatttt tgggagtttt ctcgggagtt gccaagtgtt ttcctagaac
    13021 atttgaaatg atttcactgg cagcttcctt aggatttcct aaatcgtcga taacctggct
    13081 ttctttgtca ggaccagctt catcaaaata ttcaatataa tattccatcg cttcatggta
    13141 gtcttctcta ggtagtttgc gcaagtattt atctagttct gctagatact cagtccttgt
    13201 catgtcttaa gctcccttca ataatcccgt ctaaggcaaa tttatagctc tgccattctt
    13261 tttttagaaa aatcagctgt gctctccccg aagaagtgac agcataatat ttacgctttc
    13321 gtccctgatg ttcttgacta taagttgtca aaaaacctgc cttctgcaat tttttaagaa
    13381 taggatagag ggtggattct ttgatattag ccactagttt aatggtttga ctaatatcgt
    13441 aaccgtaaga atcgtttttt tcgacaatgg ctaaaatcag aaattcaatc aaggtagccg
    13501 atactggaaa atacatttta ggctcctttc atatataaaa attttatata taattatttt
    13561 acatatttag tataagctta gttttttgat atgtcaatat tttatatata aaaaaataat
    13621 atatatcaaa aaccactaac taggagtaat aagttgacca aaaagctagg attggttatg
    13681 atgaagataa gattaacaga aagagaaatt agggaaggct atgaaggact tattaaaaca
    13741 gtattaggca aaaccactag gagaggagaa gcggtacgcc gtatttttac ctcttattct
    13801 tgtcaatgat gactggcatg tcttatatga agtcagaagt cagcatattt cacaaccggg
    13861 ggaagtttct ttcccagggg gacaagtaga aaatcaggag acacttcaag aagctgctat
    13921 ccgagaaaca gttgaggaat tgactgttga tgcgtcccag atccagctat ggggtgaaat
    13981 tgattattta gtacagtctt ctagaactat tcattgtttc gttggtcaat tagtcgttga
    14041 tgactgggaa agcatacagc ctaacgaaga agttgacaag gtctttacag tacctttacg
    14101 tcagctactt gtcactgatc ctgtctatta tcatttagaa gccactccta ttgagacaac
    14161 ggattttcct tttgaccgta ttcgtaatgg gaaatactac caatttagtc aagagtgccg
    14221 tagtattccg ttttatgaaa atctagaaga aaccatatgg ggaatgactg cccagtttac
    14281 taagtgttta accgatattc taaatgatga atcaattgca aagaaaaacc ccttagatat
    14341 tgaaaaatct aaggggagat agagcactag tttgttggcg tcaacttttt gtcaacaacc
    14401 tgtaaaggtt atttgtattt ttcttctaat tgactcatcc aaagtccgag ccaaatacca
    14461 agagcaaata acacaaaggt cataagccag gttaagatac ctgcatgact gtaggaaatg
    14521 gattcgggac tactactatt tggaataaga attaatagcg tgctggataa tacaatacca
    14581 atgataaagt ggtaaacttt tgaatgatgg tgctgtaaag cataatccat acttttagaa
    14641 aaagccaaga tggctaggac tcctccgata gcaataggta agaaagtccc taataaatcc
    14701 aaagatttga accctattaa cataggacca tagagtccta agataagtaa gagatttgac
    14761 gggcttagtc cagggaccag tactcctaaa gcaattaagg cacctgctaa aataaaggtt
    14821 aaaaagttag ctggtaaggt accgattaag tcatttaaga agtaaagacc tagtcctgaa
    14881 gtaacaaagg taaggactag ccatagccag tcaactttgt ctctttgaga ctgcttggtt
    14941 gactccttaa tcagactagg aatagtgccg acaatagcgc cagcaaatcc ccataagacg
    15001 ataacttgat agtgcttaag caaaaactca acggggaaag aaaagagagc aatacctaaa
    15061 ataccaccaa ttcctactgg taagaaaaat aagacatttt caataaagtt atccctcata
    15121 tgagctaaaa aggaaatcat tcgctcatag attcctaaaa tggctgcgag aacaccaccg
    15181 gatacaccag gtaaaataaa acctagtgca ataatcatgc ctttaaaaac tcttgaaata
    15241 aatgaaacca ttgttacctc ctgaaaagaa tgattttatt gtatcataaa tttaaagaat
    15301 tgctgacaca aagctgcata tccctactaa aataattgtt cctaataaat aatacattca
    15361 attttgaaga tattttcctt aaacaccatg tctttgtgat caagtcaagt ttgattgtca
    15421 aagttgtaaa taaattttac aaagactgta aaccttacga taattatcaa aaagataaac
    15481 gaaaaaaagc ttaggtcaaa gacttttgat agtaaactta ttgaagaagg attatagtag
    15541 ctattaaaaa ggagatttat tatgggcttt aaaaaccagt taccttatta ttgaaaaaaa
    15601 ttacagatgt cacaagaaga gcttgctgaa atgatgtatg tttcaagaag actatctcaa
    15661 actgggaaaa cggtaaaagc tatccagacc tgcaaaatct tttgatgtta agtaagtcct
    15721 tacaggttcc tttagagcaa ctaatagcag aagatatccc aaaaatgact ttaattatta
    15781 aggatgagga gattaaacaa tgtgatagga atacgcatat tatgttattt gggacactcc
    15841 taattgctat cagtatttat cctataatgt cttggttagg ttggtgggga tatggtccgg
    15901 ttgctatctt atggttgata atcatgcgta tcgccttaag aattgagcga tttaaaaaga
    15961 catatgatgt tcagacttac cgataacttg aagctatagc aaagggtgag agcttagatc
    16021 agattgataa gattaaagaa aaagcaaaat atccttatca aaaagcatgg attgttattg
    16081 cgtacacagg attgacagtg ttaataaccc tactctctat tttgtttttt catttgtttt
    16141 tttaaacacg aaaaaagcct ttgaaacgtt catttcatag gcttttctca tctcaattat
    16201 tttacttctg taaaggttaa gtattttcta ttttagctgt tataaacctt attgtatcaa
    16261 tatttattga tagttgctta ataaaaggta gagtgaatgg tagagtagtt attgcgttag
    16321 ttcagcaatc ttttcaagat aaataaatac ccacagcttc taactttcgt tgtcgtagta
    16381 accccaatag gtcatgatag ataagaatat aaaaaagggg ctgtctggct tttgcttaac
    16441 gcaagccaca gccccaagga attaacgctt ttgaccaata aaccacaatt ggttacgaac
    16501 tcgaacagga gaagagaaat aatagtctgt gtgttggatg acaatctctt ctttcagttg
    16561 tactcccgta tcctttagga ttttttgccc ctgttggtct ctaggaactt ttagaaatac
    16621 agtaatggca tcttttcgta tatctacgat acacttacgt acagctcggt taaacccgtt
    16681 atggattgga ttgatagtgg taacggtctg gtgttcaaag ttgcttacct tctgtactcg
    16741 ttcacgctgg aaaaggaagt gtcttaatag aaaggtgcga taaatagatt ggcagtagtt
    16801 cccaaggcta tctgtattca agcgttgtat catctttaat ccagataata aggctagaag
    16861 taaagaaata agagcgaatc cataacatac agaactaatg gtatcagtaa cgtttttaac
    16921 cgtatccaga ttgacaaatg tgacggtaga taattgaact gaaacaagat tgaacagcca
    16981 accgaacaca tagcagattg gagcaataag cagtaagtat aatatgagat tgaagcttct
    17041 catgaagtag gttttagtgg tcataggata cctcgcttag tatagtaggt tggacagagt
    17101 aagggtagaa cttgatagga gtgttcatta tcgacaactt gaatgatacc tgttccgtgt
    17161 cctgttggaa tgacaatccc ctctggatct aggtctggaa ataagaattg agtggttttc
    17221 tgattgatat ttccaatttg caataatacg tttagctgtt ccctcactga aatgggaata
    17281 gtgttatggt caaaacgctg gcttcccaag aatagatgga ttttagtagc atgtcccaac
    17341 aaggcaattt gtgatagtag ggagaaaaaa gcttctttga tattcttatt gactccctct
    17401 gatagagcga ggacttcatc aataacaata gttagatggg taaattgatg attgggatta
    17461 tcatacaaga tagcttgtcg tttctgaatg agagttgcac actggtttaa ttgttcattg
    17521 acttgtgaaa cgaaatcaga ttttgaatgg ttttctactg ggtggataac ggcaatttta
    17581 ttttctcttg cccattggct aggggtatcg aattttgggt caatgataat taggccggac
    17641 ataggtttca ggacactcaa gaagtaagtg agagcgtacg gtttcccaga acctgaattt
    17701 ccagcaatag cccagtgact ccccttatct aaattgagtt cgaagtgctt tatgacagga
    17761 attttcccct gttgtaagct agatgaaaat ttatctaaat caggaatcgc caagcgttct
    17821 gaaatcccct ttctccaagg gaagaataat ccacgttgaa tgtgtaagtc atccgtctct
    17881 aaagggacaa aatctgtgca aattttgatt tatctatttt ttgacttccg tttgacttaa
    17941 tcgataaagt tgaccttgct tttttggaaa taactaacgg gacggacgta aggtaagatt
    18001 ttgggatatt ttctttatac attcgttcta gaatatcatc aaccaggaat ccgatattaa
    18061 atagtggatt ttctttgagt ttttttatta ggttagggat aatttctgtc gaaacattat
    18121 cataccacca tttattgatg aggggatcaa tgttttcttg cctaaatgtt gagggtatgc
    18181 catttccgtt taattcaaat aggataccac agacattaac ttcaaatgat ttaattaaat
    18241 tatcccctaa catcaaccaa ataatatcaa acatttcttc aaaattaaag acagtcaatt
    18301 cattgatggt actggttcta aaacttctag cgaggttata acttttttca ccaacagtaa
    18361 tgtcaatgtc atctttcttg tgaaaagtat ccatttcagt ttcatcagaa gccaaaaaat
    18421 tttttctttg aatattgaaa tttgcgaatg tcttggaaag tctaagacag ctggattgta
    18481 ttgaaattaa gtcatcgtcc gaaaaagaat acattctttt atctacagtt tccaaatctc
    18541 taaataaaat agagctgaag tagtggtaaa acatattttc aacaaacttg gcaatatctc
    18601 caaaaataat ttctttatag tccgagtcgg tttgagtatt caaataaagc aatattgaag
    18661 cggtaacttg tcgctttccc ttttcaactt ggctaacttg acctgcatta cctaggtcac
    18721 tttactttaa attatacttt tttcttaaac atttgatacg agtaggtatt tcttgtgaat
    18781 aattttcttc aaaaaatttc atatataatc cccctataat catggaaaag tagaaagtag
    18841 taaaaatagt tgttatccta gttgattaaa aaaatctctg atttcctcat cttttataaa
    18901 ataatatata attttcccct ctcttctagt gtccaagatg ttttgattgg atagtttacg
    18961 aagatggtgg gaggcagatg ccatactgag atttaataaa caggctatat cgcagacaca
    19021 gagttcttcg acggcaagga gataaaagat gatatttatc tgtttattat cggtaaattt
    19081 tgataaaata cgaagtgatt tttggacttt ttccttttca aggtagttcg ttgcggttgt
    19141 aacattttgt tgatttataa cacccacttg acagatacta tcttttttca taattttttc
    19201 tcctagccta acacagccca tagcatgtca aagctgttgt tttcaatcag gatatacatc
    19261 cccaatccta aatagacaac ggcaataaac catctgctat atttttccaa agtttctcca
    19321 acagaaggga cttgtgccaa tttttgggca gaaaaaacca agagataaat catgactaga
    19381 aaggtaagta aagccactat caaattcgct aaatttaagg tagtaaaata tgggacaaag
    19441 acaccaatat tgtcagcacc acaacttgca aaagtaatca tagcgactag aaaaatcagg
    19501 tttttattat ctttgctcaa accttctttg gcaatagctt ctccatcaga atctcctaaa
    19561 agcaaaactt tgaggcctag gaaaattgga atcaaaccga gcaaacctaa aatctcttta
    19621 ctaggaatat aatctaagac aaatgcaaaa agcaaactta gcaatattag actaacagag
    19681 cctagaaatt gtcctaaata gatgttaatg atgtcttttc tgctttttct tttggcaaaa
    19741 aataacatta ggataataag taagtctacg gctgtcccag aatacaggat tattgaagta
    19801 acaacatttt gaatcataaa acacctcatt caaatatatt tttgaatgaa ttttaacatt
    19861 aaactttgta gatgtcaatt tcagctacac caaaatatag ataagaagtt agtgtaccaa
    19921 atataaaaaa gccctgccat ccaaatgata acggggctta acttcaatat ccaaatgata
    19981 tattcatcta aaaaaggtag agtaaaaggt agagttctta ttgatttata ttacaatgta
    20041 atgaacttca aaaattcaaa aatcgcttaa aatcaacgtt ttgacgtcta atgacgtgta
    20101 gtgaacccct tacttaacct ctgtaaatgt aacgtgttta cgtaattttg gtgagtattt
    20161 tttcaattga agacggtctg gagtgttacg tttgtttttt gaagtaaggt acaagcgttc
    20221 accagattct ttatgttcaa gtgtaatatt tacgcgcatg gtatctccct tctattattt
    20281 agcttcgtta gctttagcga ttttacgtcc tttgtagtat cctttaaggg atacacggtg
    20341 agaacgtgag taatctccag tagtttcgtc gaattgtaca gatggagctg tcaatttgta
    20401 gtgtgtacga cgtttgtttt tcttcgcttt tgacgtgtga cgtgcaggta ctgccatttt
    20461 cttgttcttc ctttcgatgt gtaagttttg attttcatca acttcactat gataacatat
    20521 cttttttgta aagtaaagtt acttgacaaa actttttatt tttacaattt catggtgaaa
    20581 atactatcaa actaaagcaa atgatatatg cttgtttaaa atataagaaa aaatggtaga
    20641 atgtttaaag agaaaactaa tcaaagaggt aaacttatga aacttcaaaa accaaaagga
    20701 acccaggata ttctgcctgg ggatgctgcg aaatggcagt atgtggaatc tgttgcgcgt
    20761 gatacgttta gccaatataa ttatggagaa attcgtactc ctatgtttga acactacgag
    20821 gtaatctcgc ggtctgtagg tgatacgact gatattgtga cgaaggaaat gtatgatttc
    20881 tatgataaag gagatcgtca cattaccttg cgaccagagg gtacagctcc agtggtgcgt
    20941 tcttatgttg aaaataaatt gtttgcgcca gaggtccaaa aacccgtcaa actttattat
    21001 atcggttcca tgttccgcta cgaacgtcct caagctggtc gtttacgtga atttcaccag
    21061 attggggtag aatgtttcgg cgctgctaat ccagcaacag atgttgaaac cattgcgatg
    21121 gcctatcacc tctttgaaaa attgggcatt aaggatgtca cccttcattt aaatagtttg
    21181 gggagtcctg agagtcgtgc agcttatcgt caagccttga ttgactactt aacaccaatg
    21241 cgtgatcaat tatctaaaga tagtcaacgt cgcttggatg aaaacccact gcgcgtgctt
    21301 gattctaaag aaaaagaaga taaactagcc gttgaaaagg cgccttctat tttggattac
    21361 ttagatgagg aaagtcaggc gcactttgag gcggtcaaag atatgcttga agcacttgac
    21421 attccttatg tgattgacac caatatggtg cgtggccttg attactataa ccacactatt
    21481 tttgaattca tcacgtctgt ggaaggttct gacttaacta tctgtgcggg tggacgttat
    21541 gatagtttgg taggttattt tggtgggcct gagactccag gatttggctt tggtcttggt
    21601 ttagaacgtc tcttgatgat tattgaaaag cagggcatta ccttgccaat tgagacagag
    21661 atggatattt accttgctgt gttaggtgat ggtgctaata gcaaagcttt agaattggtt
    21721 caagccattc gccgtcaagg gtttacagct gaacgagatt accttggccg taagattaag
    21781 gctcagttta aatcagctga tacctttaaa gcaaaattgg taatgacttt aggagaaagt
    21841 gaagttgaag caggcaaagc tgtgattaag aataatcgta gccgtcaaga agtggaagtc
    21901 agttttgaag atatgatgac caactttgaa aacatctcag agcaattatt gtcttaatga
    21961 ttttattgtc gtcataagct tgtgttgata tgattgttta gaagataatc actaaaacag
    22021 gtgtaacttc tctttttaga agggagttgc acctgtttgt tttctgtaag gggattgatt
    22081 agctttctta gtattctgtg aggacacctg atatgtcaaa atgctgacga ctcagtattc
    22141 ttgctttatc tttagaaaaa ctctttttaa atgggtgggg tttttaaggg ctttttgcta
    22201 taatagtagg gaatgaatta attgatttat atagtgaaag gaattggaaa cgagcaggtt
    22261 tcacaggatt ctgtttgttt tagggaattt atttatgaaa cgtagcatgt atgcagggcg
    22321 tgttcgcgaa gaacacattg gaacgacaat cacattgaaa ggatgggtca gtcgtcgtcg
    22381 tgacttgggt ggtctcatct ttattgattt gcgtgaccgt gagggtgtga tgcaattagt
    22441 cattaaccct gaggaagttt ccagtgatgt gatggcaact gctgaacgct tacgtagtga
    22501 atatgtgatt gaagtggaag gttttgttga agctcgacaa caagccaatg ataagttggc
    22561 gacaggaatg gttgagttaa aagtatctgc tttgaccatt ttaaacacag ctaaaacgac
    22621 gccttttgaa attaaagatg acgttgaagt aagtgacgac acgcgtttac gttaccgtta
    22681 cttagattta cgacgtccag aaatgttaga aaacttcaag ctacgtgcaa aagtgactca
    22741 ttctatccgt aattaccttg atgaccttga gtttatcgat gtcgagacac ctatgttgac
    22801 aaaatcaact ccagaaggtg cgcgtgacta tctggtacca agtcgtgtta gccaagggca
    22861 tttctatgct ttgccacaaa gtccgcaaat aaccaaacag ttattgatga atgctggctt
    22921 tgatcgctat tatcaaattg tgaaatgttt ccgcgatgaa gatctacgtg gtgaccgtca
    22981 acctgagttt acacaagttg acttggaaac gtcattcctt tctgaacaag aaattcaaga
    23041 catcgttgaa ggcatgattg ctaaagtgat gaaagagaca aaagaaatag atgtaaccct
    23101 accattccca cgtatgagct acgatgtagc aatgaatagc tacggctctg ataaaccaga
    23161 cacacgtttt gaaatgcttt tacaagactt gacagtaact gtcaaaggaa ttgacttcaa
    23221 ggttttctca gaagcaccag ctgtcaaggc gattgtggtg aagggaaatg cagatcgata
    23281 ctctcgtaaa gatattgaca aattaactga gtttgccaaa caatttggtg ctaaaggcct
    23341 tgcctgggtt aaggtgacag atggtcaatt ggcaggccca gcagccaagt tcttgacagc
    23401 tattgagaca gagttgtcaa gccaattaaa acttgctgag aatgatttgg ttttatttgt
    23461 agcggatact cttgaggttg ctaataatac attaggtgcg cttcgtaatc gtattgccaa
    23521 ggaccttgac atgattgatc agtcgcagtt taatttcctt tgggtggttg attggccaat
    23581 gtttgagtgg tcagaagaag aaggacgtta tatgtcagct catcacccct tcactcttcc
    23641 aacgccagaa tctgctcatg agttagaggg tgatttggct aaggtacggg ctattgctta
    23701 cgacatcgtt ttaaatggtt acgagcttgg tggtggtagc ctgcgtatca atcaaaaaga
    23761 gatgcaagag cgcatgttca aggctcttgg ctttaccgct gatgaagcta acgaccaatt
    23821 tggtttctta ctagaagcga tggactacgg ctttcctcct catggtggct tggcaattgg
    23881 tcttgaccgt tttgtcatgt tgcttgctgg aaaagacaat attcgagaag ttattgcctt
    23941 ccctaaaaat aacaaagcct ctgatccaat gacgcaagca cctagtcttg tttctgaaaa
    24001 ccaattagaa gaactcagtc ttcaaataga aagtcatgat taagaaaaca acctataaga
    24061 aaaaagttaa atatgtcatt agtagagggg ccaagaaagt tggcctactc cacgctctaa
    24121 gaagtatttc aagagaaaaa tatgcagaga agatttcggc ttctctgctt tatggcattc
    24181 tctctagtat tgctgtgaat tttttcttcc agcctgggca tgtttattca agtggagcaa
    24241 ctggtctagc acaggttttt tcagctctta gtcatcgtct tttaggctat gatattccca
    24301 tcgcctttgc gttttatttg attaatattc ctttgcttat tttagcttgg tataaaattg
    24361 ggcatcaatt taccattttt acctttatca cagtcagcat gagttctttc tttattcaaa
    24421 tcatgcctca agtgacgctg acgactgatc ctcttatcaa tgctattttt ggtggcttgg
    24481 ttatgggaat gggaattggt acaggtctca aatcacgtat ctctagtggg gggactgata
    24541 ttgtcagttt gacccttaga aaacgaacag gcaaggatgt gggcagtctc tcattgatgg
    24601 ttaatggtgc aattttagcc tttgcaggga ttttatttgg ctggcagtac gccctttatt
    24661 ctatggtctc tatctttgta tcaagtcgtg ttacggatgc catttttacc aagcaaaaga
    24721 aaatgcaggc aaccattatt accagccatc cagagcgtgt gattcatatg atccataaac
    24781 gtctgcatcg cggggtgacc agtatcaacg acgcagaagg gacttacaag catgaacaaa
    24841 aagcagtttt gatcaccatt ttgacatgtg aagaataccc agaattcaaa tggctgatgt
    24901 taaaaacaga cccacaagcc tttgtttcag tggctgagaa tgttagaatt atcggtcgtt
    24961 ttgtggaaga tgattaagaa aaacacagga ggtgtcatgt caattgacca acgtttacag
    25021 ttaaagaaat tttgctttat tattttagga gctgctatct acgcctttgc ttttgtttat
    25081 ttttacatgg ctaatcgcat tgcagccaat ggtttagctg gtctcaccct agttggtaag
    25141 gcactttttg agattgatcc ttctttgata ggctatttga ttaatttgcc tttggtgttg
    25201 ttgggagcta gatgttttgg gaaaagagcc atggtttaca cagtaacggg tattttgtca
    25261 ctttactttt ttgtgtggct ctttcaacgc tttcctttgg tcgttgactt ggatcatgac
    25321 aatttagtcg tttccttgat ggctggaatt actggtggtc taggtggcgg tcttgtgttt
    25381 cgcaatggtg gaaccatcgg tggagcagat attattgcta agttattaga agacaagtta
    25441 ggactacagc tgaatcaagc tcttttaggc attgatcttt ttgtcatgat tgtctctttg
    25501 acttatattt ccctgccgca aatgatgtat gctctgattg ctagctttat gtatggtcaa
    25561 attgttcgct tggtacaaca aggtggttat tcagcccgtg gcatttttat cgtttcagaa
    25621 caagcggaga aaattgcccg gttcatcatg gacgaattgg gaaggggagt tacttatcta
    25681 acaggtgaag gagcctactc tggtcgccgt aaaaaagtga tttatgtggc tttggggcga
    25741 agagatatta gggaattaaa agctttttta actcaggttg atcccaatgc ctttatcact
    25801 tattttgatg ttaatgaagt caatagccca gaatttttaa ctattaaaag caaataccat
    25861 aaaaagagaa aataaatgag cattagagtt gcctgcgaag aatagtgagg ataaaggatg
    25921 gcacatcacg ataaattgac taaactacta aaactgtttt tgattgccct aggtgtagcc
    25981 atttatacct tcggttttgt taattttaac atggctaatg ctttggctga aggtggtgtg
    26041 gcaggaataa ccttgatttt acacgcgcat tttgggatta atcctgctta ctcttctctc
    26101 ttatttaatc ttccactttt tattttaggg gcaaagattt ttgggaagcg ttctttggct
    26161 ctaaccatct atggaacagt tctgatgtcc gcttttatct ggatgtggca aaaagttcct
    26221 atcgaacttg gcttggaaaa tgacatgatg ttggtggctg tagtggcagg tctcttttca
    26281 gggattggga gtggcattgt ttttcgctat ggtgcaacca caggtggaac ggatattatt
    26341 ggtcgcattg cagaagaaaa atttggagct aagctaggtc aaactttgct tttggtggat
    26401 gctcttgtat tgacagcttc gttgacttat gtggatttaa aacacatgct ttatactttg
    26461 gtggcaagct ttgtttttag ccaaatgatt agtgtggttc aaaatggtgg ttacactatc
    26521 cgtggaatga ttattattac caagcattca gaggctgccg ctcaagctat cctaaccgaa
    26581 atcaatcgtg gagtgactta cttgaaaggt caaggagctt actctggtaa tgattacaat
    26641 atcatgtatg tgaccttgaa cccaactgaa gttcgggaag tcaaacgtat tttagctggt
    26701 ttggatccag atgcctttat ctccattatt gatgtggacg aagttattag ctctgatttt
    26761 aaaattcgcc gaagaaatta tgataaataa aaatacaggt caaacagcct gtatttttat
    26821 tttggtcccc cacttaagaa actaccaagc ataatagctg atatagcagt tcccttgtaa
    26881 tggcaagctt ttgtttttac caagcgacta agatcaaata tgcttttagg agcatcaaat
    26941 tgatgtgtta agatgtattg attgataagt gagtcaattt ttgtagctag tagtgagctc
    27001 atcctctctt tttcaagttg actggcgagc tcgaagatcg cttgacgaaa ataatcatcg
    27061 gtttgtatta ccggttcgct ataaacttta ctaagagcat ctaatatttc tttttctgat
    27121 ggcatggcat tctcctgtaa catattgtgc tattattata atataaaaaa ctaagactgt
    27181 cataaatgtg acagccttag taatgttatt acttacattt catttggtgc gtcaacaccg
    27241 agtaagcgaa gcgcttcttt aagaacagta gcagttgcac agcagagagc taagcggtta
    27301 tcacgttctg agttgtcgtc aagaatgcga gtgtgagcat aatatttgtt aaagctttgg
    27361 gctaagttaa tagcaaattt agccataata gaaggctcaa agttatctga tgttcgcttg
    27421 ataatgcgtg ggaaatcttg gataagtttg ataatttccc agctttcagc atcagctaaa
    27481 ctgtaagtgg tggttgcaga tggcgtaaag tcagctttac gtagaataga ttggatacga
    27541 gcatgagcat attgaacgta aggtccagtt tctccttcaa aggaaaccat ggcttcaagg
    27601 tcaaagtcat acccattcat acgatctgtt ttgagatcgt aaaacttgat ggcaccaaca
    27661 ccaacggcat gggcaacggc ttctttgtca gcaaggtttg gatttttcgc ttcaatttga
    27721 gaagctgcac ggttaatggc ttcagcaact gtaggttcaa gaagaataac attaccttta
    27781 cgtgttgata atttagcacc gccttttgtg acaagtccaa aagcaacgtg tgtcatgtca
    27841 tctgaccaat cgtaacccat ttcttttagc actgctttta actgtttgaa gtgagcagct
    27901 tgctcattac caacaacata aacggattta gcaaagtcgt aagtgcgttt acggtaaagt
    27961 gcggcagcta ggtcacgggt aatgtaaaga gtagcgccat ctgatttttt gatcaaggca
    28021 gggtgttcaa tgccgtattt ttcaaggtta acaacttggg cacctttgga ttctacaaga
    28081 aggtttttcg cttctaatag ctcaagaacc tcatccattt tgtcattata gaaggcctca
    28141 ccgttgtaac tatcgaaggt gacatgtaat tggtcataaa gtcggttgaa ctcaagtaaa
    28201 ctttcatcac ggaaccattg ccataattca gtagcttctt tgtcgccatc ttccaattta
    28261 cggaaccatt cacgagcttc ttcatcgacg gttggatcaa tttcagcttc agcattgata
    28321 cgaacgtaaa gttttaagag ttcatcaata ggatgtgcct gaacagcagc ttcctctccc
    28381 cattttttgt aggcaacaat gagcatacca aattgtttac cccagtcacc aaggtgattg
    28441 atttttacag gttgataacc cattttagca aagatattag caaggctatc accaataaca
    28501 gttgagcgga ggtgaccgat tgaaaatggt ttagcaatat ttgggcttga catgtcaata
    28561 gcaacatttc gcccttgacc ttcgtcttgc tgagcatagt ctgaacctgc tgtaatcact
    28621 tgttcaagga cctgtgagga aatcttagtt ttatcaagga aaaagttgat gtaagggccg
    28681 acagctacga ctttttcaaa ttggctctca tcaatctgtt cagctaactc gctagcaatc
    28741 atttgagggg ctttgcgaag gacttttgct aaactaaagg ctggaaaggc aaggtctccc
    28801 atgtcagaat tttttggggt ttcaagcaag ttaaaaatag catcttgttc taactcaggg
    28861 acaactttag ctatttcact tgcgattaga gttttagtat ccatacggcg tctcctaaaa
    28921 attgtttgtc accctattct aacatatttc tttaaaataa acgaggagag gattgataaa
    28981 ttatactgaa actttcaagg aaatgaattg cttgaggttg ttatttttct gaaaatgtta
    29041 taaaaagaga aatgagattt cttttcaaca gttttcaagt gaaattctag ttggatttga
    29101 taaaaaattg ctgaaaatag ctgggcgaag atgaaataat acactttttt tgttataatt
    29161 tgagaggata attatacaat tggggtgata tatcatgaat aaaatggagc gtcaacagca
    29221 gattaagcga atcattcaag cagagcatat tggcacacaa gaagatatta aaaatcacct
    29281 tcaaaaagaa ggcattgtgg tcacccaagc aactctatct cgggacttaa gagaaattgg
    29341 ccttttgaaa ttgagagatg aacaaggcaa actctattat agtttgtctg aacccgttgc
    29401 aacaccattt agtcctgagg tgcgttttta tgttttgaaa gttgatcgag caggttttat
    29461 gctggttctc cataccaatt taggagaggc tgatgttcta gctaatttga ttgacaatga
    29521 tgccattgaa gatattctag gaaccattgc tggtgcggat accttgcttg tgatttgcag
    29581 agacgaagag attgctaaac gctttgaaaa agatttggct gcaggcctat gactagctat
    29641 taagagtctt tgacacaatt gattcttgct atccatgaat tctagtatcg ttgcttataa
    29701 agaagtgaag caatagctgt ctaagctcca tgattttaaa aagtaagctt atcagatgaa
    29761 acgctatcaa caagatgccc tgcttttcaa aaaaaataga taaagaaaag gctgcgacag
    29821 tatctgcaag caggtcaaaa gaactagaag ataggctcag tcatcagcca ttaattgatg
    29881 attatcgaga aaagatgcaa gatgcaagtg atgtgattca gtatatcacc aaacgtatag
    29941 aagatcagtt aaacaaggag ttaacaaatg gcaaaaacta acatttctcc tggaatgcaa
    30001 cagtatctgg acatcaaaaa agattatcca gatgcttttt tgctttttag gatgggtgac
    30061 ttttatgaat tattttacga ggacgctgtc aaagcagcac aactcttaga aattggtttg
    30121 accagtcgca acaagaatgc ggaaaatcca attcctatgg caggcgtgcc acatcattct
    30181 gcccaacaat acattgatgt gttaattgag ttgggttaca aggttgctgt cgcagaacaa
    30241 atggaagacc caaagcaagc tgttggggtg gtgaagcgtg aggtcgttca agtcataact
    30301 cctggaacgg ttgtggattc agctaagcca gatagcgcca ataacttttt ggtagctgtt
    30361 gactttgatg gttgccgtta tggattggct tatatggatg tatccacagg tgaattttgc
    30421 gtgacagatt tggcggactt tacgagtgtt cgtagcgaaa tccaaaacct caaggcaaaa
    30481 gaagtcttac taggttttga tttatctgaa gaagaacaga cgattttggt caagcagatg
    30541 aatttgctgc tttcttatga agaaacggtc tatgaagata aatctttaat tgacggccaa
    30601 ttgacaacgg tagaactgac agcggcagga aaactcttgc aatacgttca caaaacacaa
    30661 atgcgagaac tcagccactt gcaagccttg gttcactatg agatcaagga ttatttgcag
    30721 atgtcgtatg ccactaagtc aagtttagat ttggtagaaa atgctaggac taataaaaaa
    30781 catggaagtc tgtattggct tttagatgaa accaagacag ctatggggat gaggcttttg
    30841 cgctcatgga ttgatcgacc tttggtttct aaagaagcta ttttagagcg tcaagaaatt
    30901 attcaagttt ttctgaatgc ttttattgag cgaaccgatt taagcaatag tttaaaaggt
    30961 gtttacgaca tcgaacgctt atctagtcgc gtgtcttttg gcaaggcaaa tccgaaagat
    31021 ttacttcaat tggggcatac cttagcccaa gtgccttata tcaaagctat cttagagtct
    31081 tttaacagtc cttgtgttga caaacttgtc aatgatattg acagtttgcc tgagttggaa
    31141 tacttgatta gaacagccat tgatccagat gcaccagcaa ctattagtga aggcagtatt
    31201 attcgtactg gttttgatga gcgcttggac tattatcgta aagtgatgcg agaaggaaca
    31261 ggctggattg cggatattga ggccaaagag cgtcaagaaa gtggcattaa taacctaaaa
    31321 attgattaca ataaaaaaga tggttattat tttcacgtta cgaattcaaa tcttagctta
    31381 gttcccgagc attttttcag aaaggcaact ttaaaaaatt ctgagcgtta tggaacagca
    31441 gaattggcta agattgaagg tcagatgtta gaggctaggg aagagtcatc tagtttagaa
    31501 tacgatattt ttatgtgtat tcgagctcaa gttgaaacct atattaatcg tttacagaaa
    31561 ctggctaaaa ctttggcaac ggtggatgtt ttgcaaagtt tagcagtagt tgctgaaacc
    31621 aatcattata ttcggccgca gttcaatgat aatcatgtga ttacaattca agaaggtcgt
    31681 cacgccgttg ttgaaaaggt tatgggagtg caggaataca ttcccaatag tatctctttt
    31741 gaccaacaga ccagtattca gctgattaca ggtccaaata tgagtggtaa gtcgacttat
    31801 atgagacagc tggccttaac ggttatcatg gcccagatgg gttcatttgt ggctgctgac
    31861 catgttgatt tacctttatt tgatgcgatt tttacgcgta ttggggctgc tgatgatttg
    31921 atttctgggc aatcaacctt tatggtggag atgatggaag caaaccaagc aatcaaacgc
    31981 gcaagtgaca actctcttat tctatttgat gaactgggac gaggtacggc aacttatgat
    32041 ggtatggctt tagcccaggc aattattgaa tatatccatg atagagttgg tgctaagacc
    32101 atatttgcaa cgcattatca tgaattgaca gacttgtcaa ctaagttgac aagtctagtc
    32161 aatgttcatg tagcaacgct tgaaaaagat ggcgatgtta ccttccttca taagattgct
    32221 gagggaccgg cggataaatc ttacggtatt catgtggcaa aaatagcagg actgccaaaa
    32281 tccctattaa agagagcaga cgaagttctg acccgtttag aaacacagtc acgatctact
    32341 gagataatat cagtcccttc acaagttgag tcaagcagcg ctgttagaca ggggcaatta
    32401 tccctttttg gtgatgaaga gaaaactcat gagattaggc aagcactgga agctattgat
    32461 gtcatgaaca tgaccccgct tcaagcaatg acaacccttt acgaattgaa aaagttgtta
    32521 tagtctttca gctgaaaatg aaaaagatgc cttcaatata gaaagcatct ttttgttctg
    32581 tcaaaaacgg tccgaggcct tcggctattt attaagtgtg ttataatagt ccataagaat
    32641 gcgaggaaat tatgacaaac attattggac ttggattggc agtctttaca gggtattgac
    32701 agtccttaag cattgatatg actgtgtttt tgaaaaaata taggttttaa gtttccttag
    32761 acttccctca aaagtccaca aaaaggtgaa caaaaaaaga cctttgcagg tcctttacac
    32821 aatgagttca gcaggcaaga actagcgtgg tttagatact acgcttttag tttgccctat
    32881 ggcttattat agcacgatta gtgtcattga ggaaaaaact accctctcaa ccagtcttta
    32941 aagttccacc attggtcttg gatgctatcg ctcaagcgtt gatgccaagt ttttttggat
    33001 tcttcttcga tagaacgctt gaataactcc tccgcatatt gttgctcttc ggcatctctc
    33061 tctttttgaa gacgttcatt atgtgttttt ccatcctcaa atacaagttg cccaaagtat
    33121 agattcccgt catccgcaaa agataaggta actttgtctc cttcagcaag tggtttttcc
    33181 aattgaactg tgtagttgcc tcctccatca gcacgattgc cacttactgt ccatttcctt
    33241 ccttcgcagt ttcgattatc ttgtttctcc aaaatagagc aaggaatttc ataagttttg
    33301 ttttcgggtt ttttaatttt attaccatta cttgaagtta caaaaccata aacataccca
    33361 tagggatcta gattaacatt aatggttgta tctcctgttt taaatggtgc tacggttact
    33421 ccaggtaagt gcgattgccc tatagttgta aacaaatcgc cactttcatt agctctgaca
    33481 cttatagcac atattgatat taacaaagtt aacatcataa ctaatttctt tttcactata
    33541 ttctccttaa aattaaatat cgaactccac aataccagtt aatcagtcaa aaaatccatt
    33601 ctactttttg atattttatg tctaatttga cccaccaagt cagctttgca aacgatacca
    33661 agttcgtttc ttctaatcgt tattttctag atggatgtgt taactgtatt agagacgtat
    33721 taatcttaaa ccattgtcat aaacgaacat tattttttag cactccatcc ctgtaaaatt
    33781 ccacaaactc aagcaaagct cgtttcttag tctcatagta ccaactttga cttctgttaa
    33841 gttctgctat gatgtcttgt tgaggttttt tctcactgat caagtaacac tcaatcagta
    33901 tctttctgta atctagttta gacagttgat taatggcata cctaatagcg tctagttcct
    33961 ctagggcgca ttctcggctt atttcaaggt gttttctgcg cgtgggatgg tactctatat
    34021 caaactggta aagctcggta taagttaaat caaggctatt agcgatacgt tgccatctat
    34081 ggaattcttt cagcttacga atagcgttct tcttgctcat ctaacacctc taaagcttct
    34141 ctatgtagtt tgaacacagt gtttcttgag taacctagtt tatcgagtat ctcgtcccat
    34201 gataagtcat ccacgtatct agccttaata acagctatct gtctctcatc ttggagtgtg
    34261 gcgatcatgg ctagtctctt atcacgttct ttagctaaat ataagagttg tttagctgta
    34321 cctttttcga tatgtcttat tgcttcagga ttatgaaaag catttatcag cttgatgtct
    34381 ttatctcgtt gttcctcaaa taaggttatt aaagcgaaaa gtggtttcaa ttctttaagt
    34441 tgttctttag cgctcatggt cttttctcct ggttatggta taatttattt aagcttaaat
    34501 ttaaccaagg ggtgttccgt gtggacgtct ttttgttttg ttcattttgt aaactagata
    34561 ttttttgtag tacttcgctt ttggcttcta aaatcgtttc taagcacttt ttagagttta
    34621 tagtataaat catcaactta gtagctagaa gcgctaaaac aatgttttat tttagtctta
    34681 gatggttatt ctttgtggca gggttatggg ctaaaatgag atgtcaaatc ctttcatatc
    34741 aagtttttaa tcttcggtga aaatttcaaa aagggaattt tttgcacgga aaagggcgcg
    34801 ttcttaagtt tccgaacaat atagccccgt ttaaaaatga agggggtagt ttccgaatat
    34861 tatagccaat acctgtcacc cttatccata tagtaatgaa atcttctcca gtgataaagg
    34921 tatttggtta atctcatgta ctttggacgt ttaggaaagt catcacgact ataatatcca
    34981 tgaatgtgtc ttgcttctgg atttactttc aaacactctt taaaggctaa ttgccagtag
    35041 tagcaacagt ctgtcttgct tcgattgagc gtggcttgat gaaccttctg acaagaacca
    35101 caagcaaagg catgagaagc cttaaataat ttccgacaac gtctctcaca gtaaggacac
    35161 acgaaaaagt aacgtttgcc accataagtt cctggaatcg tttcaagcaa taggccttga
    35221 ccattgtagt gaatcactag cccatctagg tctatgcgga tagcttggtc acctattgat
    35281 cctgtaactc ttgtcttccc ctgtatcttc attggtttaa tgatattttc aatagatagt
    35341 tctaacattc tttctcctta aaactcaaac aacccaaaac tattgataaa acgacaaaaa
    35401 gagggaaaac cctctgaatg tctatttaac gagtaactga ccttcaacaa ccatatcata
    35461 caaatggtta aaggcttgac tgatagactc aaggatggcc cctaagtctt ctggcgtcat
    35521 ctctttataa ttcatagagt ggtgttcagc cagttggttg tgatcggaga tgaaggctat
    35581 aagtgtgtct cgattattaa ctttcccttg agtactttta gataaagaaa ccacgcgctg
    35641 atgatcaagt tcttcatccg tcatatcctc aggttggttg taatagtcct tgaaactatc
    35701 acagatacgc ttgaagacct tgcttaactt tctgtcttca gcatatttta agactaactg
    35761 attagcatga ccaccttggt catcattgtg ataagttgcg tcaatcactg gttgctcata
    35821 ggtcccagtc atatagccta aaatagcatg gcaggctact tgtgcggtat caaagtcttt
    35881 aaacgtgtag tggaatgtga atgtctttgg tgtgtctgaa aatgttctca tgctatttct
    35941 cctttgtgat tgctataatg tctgataaat tgatgatggc agaaggacat gccacccagt
    36001 ttggttgttg gccagataaa agatatttgg tcaactcatc atagagggtg cggtctcctt
    36061 gtatggttat ggtattgcca cctcgtgtgt gtaattttag tttcatatca gttacctgta
    36121 caagaccagt agtcctgttc ttgaatccat gtcttcataa ttgccataag tggcttcttg
    36181 gaatttaatg tctatcacag ataccgatag ggtaaagaga ttgacccgat gttcaaaatc
    36241 atctagtgat tcattgtgtt tttgataaaa tagtttgatt ttcatgtttt agctcctttc
    36301 tcaacaggta tcgcaaagcc acagtcaaag acccattggt aaccacgtcg tgttagttct
    36361 ggtctggtaa aatcacaatc acccggtcta gactttgtgt tgaaattaat tttggtgata
    36421 aagtcataac cgcattgacc attaggaagt tccaatcggt atagctggtc gtttggcaaa
    36481 tcatcataat tgtaacgcat tttctttacg ccatgatttg tatagttagg attcatatgt
    36541 ccctcttttc tctctaaaat gtgtgctttt tgttttttta aaaatcaaat agcacagcaa
    36601 aaagcacagg gataaagcca gtggtatcaa gggggttggg cactttgtgc ttttagtagc
    36661 attaatttga gcaaaagact ttcttttttt gcacgcgcac tattagttat aaatattatt
    36721 atctataata ttaaatacta ctaatactac aatagagtat aaagcctata ataccaaggt
    36781 tttagcttgt atcattacgt gtagttttta tgtagcatta gtgtagtttt taaactcgtt
    36841 catagtaagg tacgggagtt ccacctttaa atagtctttt tcttgcggga ttctctcctt
    36901 ttttccagcc gtcatcatta tctaagtaat cacgtatttt ttgagaaata agggccttac
    36961 caccttgcgt tggtttttgg ttaaatccta gataagcgat atggttagga cttgtcactt
    37021 ggagtaagca atctgtctgt gcggaagggt agtcactata gctttgagca ttatctaacg
    37081 gctctcctag ctgtttgagg atgtattgcc gttgttcata ctgtgataag ctatcccaac
    37141 cttcaacaat ttgaaactca ttcagtaatt gatcgataat ttctttgtcg acgtcttcaa
    37201 ccttataatc ttcttgaatg tctgctaact gattcattaa ctctttagat ggcgttagtg
    37261 gttcataatt gttaaaccat actttggctt cagcgagtac ctgtaagaaa taatcttctt
    37321 ccacctccat aggatgtttt ttcacgtcat tgataccaca ttcaataggg aaaaagcgtc
    37381 tttctgttcc actatcctta agaaaagatt ttttattagc tgttcgataa agacacagtg
    37441 ccttggatga ggagtggctt tacgttcata aggttcacga taagtatcac tatctgagga
    37501 aatgaagctt ttaactgttt caatttctgc ctttgacatg ccttttagct cccctagctc
    37561 aataatggca ttggcttgta tcttctgata atcactatca tttttaccaa acttgatttc
    37621 tgaatcagtg tggtagctag ggagtagtcg cttagtaacg gtgcttttcc cagttccttg
    37681 tcttttatca atgagaatag gaacgacttc aaactttact ttacggagat aaattctagc
    37741 catgagacct gttagccata ctttggcaat ttctctatta taggaattat cagcacagcc
    37801 taatagatca ataaagtagc gttctcctct agctttacca tcccattttt gactttcaat
    37861 acgctgttta atggggtgat aagtgttctt tttagctaaa gcggtaatag ctacctctat
    37921 atgttcttta cgaggggtaa accgatattt ttcatcaatg aatgcaatac aaaggctggt
    37981 ctgctcgttc gtccatagcc ctttttcttt agaccaagga actgctttag tgatttcaat
    38041 agttttttca aattcgttgt atttaatacc tgtatagata ttttcgtaaa attcaaaaac
    38101 cttaccgaca ttgtaggggc tactaatgac atattctttg tctcctctac cttttcgtgt
    38161 cctgaaagca ggggcaaaag caggttgagt ggcttgcgat agtttatttt gatagtcttt
    38221 caattcttct ttgtctatgg cttgattcct ctctttctta attctttatc aagtatgctt
    38281 ctaaaggttg tatctatctc atcaatgggt agtggcttag ttgtcacgct gttagctatt
    38341 tgtaccagct cataagccgt ctctaaatca caatccaccc atttattaaa tagcaagcca
    38401 acaaatttag ttaaggccac gttgcgcccg ccttcgtctc caaaaccatt aaacagggta
    38461 tctatgaccc tcatggtaat agaacgctga cttctagggc gtggcgtgta agtagtaaca
    38521 acttgtctgt ttggcgtgtt accattttta ggaacaggat aaccaagacc acggttcaca
    38581 tagcgctgat agtcctctgg gtcgcctgtt gtaataggta agccttgtaa ttgtgaccag
    38641 gtaaggctag ctaaatcaaa cggtagtcca atcttatcgg ctatctcctt gaccacttgt
    38701 ttataagttg cttcagtcat cacgtcacta ggcttcatga caaggcgata acggggcttc
    38761 tcgggggtgt gtttaatcgt tggataaata atataactat actcccaaag cgtctgagaa
    38821 acgattttag gtaggttgac gcctgtttct atctcgtcat agtcaagaaa aatcaaatcg
    38881 cgataaacta aactagcatt attgcgctta tagctaccgt ttttctcggc tgtgaccttg
    38941 ccacttaggc agtagggggc ttgtgttcgc ttgtattctt caatatcaat atcctcaggc
    39001 ggtttcaaag gtctaaattg agcaatatag tcaaatggtt ctaaaggtcc tttgtagggg
    39061 tacaaataag agctaaagcc tcttgcttca taaatagcca tctacacact tacccccaaa
    39121 aagataagaa tatcactgac cttgtaataa tgtttcctgg tgtcttctag tggtggttgg
    39181 tatcgtctta acccagcatt ttcccaccgt tttagggttt tacctttgat atttaattcc
    39241 tctttgactt gttcggccgt gatcaaccct aaaactcttg gtttaggttt ctggtaggct
    39301 tccaaaaagc gattaaaagc ggtcaggttt tgttctaaga gtttggattc ataatcttga
    39361 ctaaatacgt tcatgcctaa cctcctttga gtaattcctt ataactggtt aaatcggcat
    39421 tcaataaaac acttaggcgt tcttgttcct tttgtacttg gttgtaaaag gctttagcac
    39481 cgtctagcaa ttcttctttg ttagctggaa taaagtaacc acgattgaat ccgtgcctaa
    39541 tgccgataat agggacgtta tagcgcgtga ttaagctact gatgatactt tggacggagc
    39601 gttcttcaag tttcagtatt aagctaatct ctgccccaac cttaatcaga ttaaggacac
    39661 gtctataatt ctctggtagt gtcatttcgt gtcctcctta tcatttggaa acaggatttg
    39721 gttatcaata acaccaagca cttgattttt aagactatct tttaactcgt tcaatgcttg
    39781 tataactata tttagccctt ttttatattc catctctatt ggtattgatt ccaaaaattt
    39841 aacaacggca tcagctttgt tatagttacg ttgtgtagta ttgataaata tttttttcgt
    39901 gaataacgga aaatcgtccc actctgcttc aatatcttca tctagcattt tgatattttt
    39961 gtctaaaacc ctatcactca accagtttgt aggctgtttt tcgctatctt ctagcaattt
    40021 tttaaaatat tcttccgttg tcatgcagtt cctccctaat tgtaataatg gttctgtgat
    40081 tgaatataag ccccatagtt tgcgttctta ggtggtttag ggacttgggt atcttctggt
    40141 aaatcaatgt ctattaatga cttagaaagg ctaagaagaa gccctaagag acttaaaaca
    40201 aagaatagaa taagcgtctg tgttggtgtg aggttaagtt cttgcatcat gccgatacct
    40261 cacttaaata agtttctagt tcccctgagt ctttctctga acaaggtaaa ccgttaacgg
    40321 ctctaaagac aatctctgtg gttcgttgat agtctaaagc gtcccatgct tcttcaaagc
    40381 tggtggcact ttttctgaat ttaatgacgt actctgtcat aacgttagca ataattaccc
    40441 aagcgatatg ttggttatat agtcgagtga aataggcttc tgctttattt ttgctgagtt
    40501 ggcgattttt gaacatttct agctgttcag gagtgtatct atcttttgaa aaaggatttg
    40561 tttctactct atatttcatt atgttttttc tcgcttaatt attattttct gtgtagtgtt
    40621 tttattgatt gcttgtttct tatactagat tcatgctagt tttaaggggt agctccctac
    40681 gtatggtcaa aatagcttca atatgctata atttaagaca taaaacccct ttaataatag
    40741 cttgcctgct ttattaattg agtttagtta tactaattaa aggcttggaa gtttggtcgc
    40801 tgtcaaagcc tttttttgtt gctcttgatt attgattaat aattgccttg ttcaatgtca
    40861 ttcaaacgct tttgctctgc tttgcgatta tagattagca ctttgtcatc aagcatgagc
    40921 gatacgcctt ccaatacgtt gaaaatttcc tgtgtgattg cttcaaactg ttcgcgatct
    40981 gcatttggta ctttgtcagc gtaaccctgt gctagctcag ctaaatcaac accttcatca
    41041 atccatttct tcaactcttt gtaagttgtt gctttcataa tcatttctcc tttatccacg
    41101 cgcatcactg cgcttttttt attgtgtttt ggttaaagat tgcttcagat acgctaaaat
    41161 ttaagccgta tttttcttta accttgatta gttcaaccgt ttcatcaagg ataggctcac
    41221 ggtctcgcaa catgttttct gtcatctcgt ttttactaat catctttggt aacccatact
    41281 tattagatac cgctttattg gcaatcgtgt tggctttgat aaggtctttc ttagttgcat
    41341 tttgtaagcc attgacaagc ctattcattg actgcttctg atgttcttta tcaaacattc
    41401 taaatacttg gaagccctct aggcctgtgc tttgtcttaa ctgtttaatg gtttcaaata
    41461 cccattcttg gaaagcttcc gcctcaggtt ttcgactttt gaatactaat ctgtaaatat
    41521 ctttttcatt gataatagaa agctcttgct ccccaccttt tgtaagggtc ttacttttag
    41581 taaccccctt tagagtcgat atagctcttg acggttgttt taatcccaaa gcatttgtaa
    41641 tatccttggc aaccgcccac cattcgcctt ggtgctctac aaatcggata gtatatccgt
    41701 tccatgtttc tgttttgttc atagattgct cctacaagct gatcagcttc actagttgct
    41761 gaactcggtc aatcccattt gaaatatcag ctagattatc catatcaact aaatcagcta
    41821 gcttatttcg tatataagtt aggtcactta tacctggtag tttttgggtg cttgattgag
    41881 ctagttcttg caccaattcg ccttgcatgt aatagccatt caagcggatt tcttttagaa
    41941 tgtttttgac tgcttttcta aactctttgg cttttggttt gtttgaacgc ataagcactt
    42001 cataaagtcc atgctcagtt aaaaaccaaa ctttttgacc actacgaaaa tttttcgtag
    42061 taccttctaa agccattcct ttaagctttt catcctcatc tacttttctt agcatagctt
    42121 gtacgtcata gtacccttgg ctagtttttg tgtaatcaat catttcagcg actgccctag
    42181 ccaaaaataa aggctcctga atatcaccgt aaatgtctaa aggttgtcca tgaaaatttg
    42241 tcgttgtaat aacttgcata acctgctttg tgttgtcatt agcttcttca aaaatattta
    42301 cttgtgtcat catagtttct ttcacctctc tatatagcct attcagtttc tttctgcttt
    42361 cttggttcgg gttatgttta ccctgccacc atttaccaac tgttcggggg tctattccga
    42421 tacgttgacc aatagcaact aaattcaagt tgtaggaagt tctcagctca tctatgacct
    42481 tgctataatt ccttctcatt tcttgcctgc ctttctaatt aataaagtac tattattttc
    42541 gtactttttt acctaaaaaa aggttatcaa tagtgacacc gtacaaagat gataattttt
    42601 gcaatagtcc taaagaaata tcggagctat ctttttcgta ctttgaaata gtttggggat
    42661 ttttcccaac cgctccagct acttgtttta aagtgtaacc agcgttgatt cgggcagctt
    42721 ttagtgtaat ttgcgtcatg ttttcaactc ctttctaaaa agctatggct taatagtact
    42781 attattttcg taccaagtca atgatttttg tagaaaaata ttaaaaaaat agtactttta
    42841 ggtttatttg tgttagaatt aattcagata caaaaagaaa ggggtaagag aaatggctaa
    42901 aaatagtccc caagatttaa taaatagaga aattttctca acaaatctca acatgcttat
    42961 ggctaaaaag aatatcaaac agatagatat tcacaacaaa ctaggaatac ctaagagtac
    43021 gataactggc tatgttaaag gtcgttcact cccaactgct ggaaacgttc aaaagctggc
    43081 ggacttcttc ggagttctaa aatcagacat tgacccccgt tttgattcta ataatattga
    43141 aacaaatagt aatattatcc catcaaccct acaaaaagta acatctactt tatctcagct
    43201 agaacacaag cgacaattaa acgtccttga ttatgctgaa acacaattag aacaacaaaa
    43261 cacagtagaa gaaccacaag ccacctacta cacttacaat tactacgacc acgcagcttc
    43321 agctggtaca ggtcagtatc taaatgatgt acaagtagaa acaattgaat taccagtcga
    43381 ttacgacgct gattttgtca taccggttta tggcgattct atggaacccg aataccattc
    43441 tggggactat gtatttatca aactatctat taacctgtca gatggtgata taggagtttt
    43501 tgagtattac ggtgatgctt atatcaaaca acttgttata aacgattctg gagcatttct
    43561 gcatagtctg aacgacaagt atgacgatat actcatagat agagatagtg atttccgtat
    43621 tatcggagaa gttattggga gttttacatc taaatcatga ctatctgata cccacgcgcc
    43681 gaattccact attttccact aattttggtt gctttacctt taaggactcg cattttgctc
    43741 tttaagacag ccgaaaagtc cgattttctg aatactatat gctaaaaatg ccaactgatt
    43801 ttagaagctg tcacaacgga aaaagtaaat taataaacga ccgatatatc aagttcttta
    43861 agtgaattta ccgagcgttt tagaactatt gaaataggtt gacgtattat gtcggtacat
    43921 accaacattt tccagcattc cgaaatgcga ccatgtgttc gtgtttggga gtagtaacct
    43981 tctattctct aagttcgctc gaagttcagc attatgcgcg tggttgtatt tcaataaaag
    44041 gagattttct atgagtataa acaaaaagca agtatttttg acactgtgtg gtatttctat
    44101 ttcagtgaca ggtattgata tgcttctatc tggtgagtat ctaagaggag ttatcaagtt
    44161 gattttagct tttggaattt ttgtcatatt tagcaaagat agagatgaat agcccatagt
    44221 ttctatttta agttcgaaaa tgcccactat aatgtgttaa aacagacatg aaatactcta
    44281 gcagtgtaaa actatactcc actgctttaa gtctaaaaat gagctaccag agtagaaaaa
    44341 acgacttata actaaaacta ttatcttatc tgttaagcag ttgcataaaa tatcataaaa
    44401 atatacataa aattattttt attcattttt aactcaccgt accttgaccg ttagaccata
    44461 gaaaggaaaa gcatgaacgg attacaacat tatgacgaat tagctttcga aaatattaaa
    44521 cacatagatg aaaacggtgt agagttttgg tatgcccgtg aattacaaac tgttttagag
    44581 tatgctaaat gggacaattt tttaaacgtt attgagcggg ctaaaatagc ttgtgaaaac
    44641 actggaaacc ccgtcgctat gaattttccc gaggtcagca aaattgtaca gctccctcta
    44701 ggagataggg agattaaaga ttataaacta tctcgctatg cctgctattt gattgtccaa
    44761 aatggtgacc ctagaaaaga agtcattgca ctgggtcaat catattttgc tattaaaacc
    44821 cgtcagcaag aactagctga taatttcaac aaactcgatg aagagcacaa acgtttagcg
    44881 attcgccaag agatgaagga acataataaa tcattagctg aagctgctaa aatgtcgggt
    44941 gtcactaact acggcaagtt tcaaaacttt ggatataaag gcctttatgg tggaatgtct
    45001 atgcaagata ttcatgatag aaaagaacta gaaaaagggc aaagtattct tgattatatg
    45061 ggtagtgctg aattggccgc taacttattc cgtgctactc aaaccgatga agtgttaaga
    45121 aatcggcaga tacacgatga aaatctagct aacgatacac actttaacgt aggtagaaca
    45181 atcagaaaaa caatgcagaa actaggcaca actatgcccg aaaatctccc tacacctcaa
    45241 gagagtatcc aagatttgaa aaagaaacat aaacaactag ataaacaacc agacgataat
    45301 caactttcac tttttgatga tatgtaaaaa ataggcaata atatcctcgt atagctattt
    45361 caactctcaa tcatataatt ttatcaactt accccccaaa aaaaaaacaa aaaagacccc
    45421 gcaagttttc cacgctcgca aggtcttaaa aagcctaata ttataccatg attttctttt
    45481 ataatatttc ggatatttac ccgataccat tattatacca tgatatgaac taatctaaaa
    45541 cccttttaat aatagcttgc ctgctgatgg aaaggtttat aatcatgaaa ataaaagaac
    45601 ataagaagaa aaacggtgca atcgtttatc gtgctagtat ttatctaggc attgaccaaa
    45661 tgacaggtaa gagagtaaaa acaagcatca caggaagaac acaaacagag gtcaagcaaa
    45721 aacccaagca cgcgcagttt gacttcctgt ctaatggatc tacaataaaa agaaaagttg
    45781 tgattaaaac atttaaagaa cttagtcatt tatggcttga aacctataag ttaacagtaa
    45841 agcctcaaac ttatgatgct actgttacta gacttaatcg acatattatg ccaactctgg
    45901 gcaatatgaa ggttgataag ataaccgcta gtgatattca aatgctaatt aatagattat
    45961 ctaaatatta tgtcaattat actgcggtac gttcagtcat ccgaaaagtt ctccaacaag
    46021 gagtattgct agggctaata gattacaacc cagcaagaga tattatcctt ccaaggaagc
    46081 agccaaacgc taagaaaaaa gttaagttta ttgatccgtc tgatttgaag tcttttttag
    46141 aacatttaga atctagtcaa cacaaacgct ataaccttta ctttgatgca gttctctacc
    46201 aacttttatt atccactggc ttgaggatag gcgaagcctg tgcattagag tggggagata
    46261 ttgacctaga aaatggtaca atagccatta ataagactta caataaaaat ttgaagtttt
    46321 tgagtacagc taaaacccag tctggtaata gagtgattag tgttgataaa aagaccctta
    46381 gaagcctaaa gctctatcaa atgagacagc gacaattatt taatgaggtt ggtgcgcgtg
    46441 tgtcggaggt agtgtttgcc acaccaacac gaaagtattt taatgcttcg gttagacaaa
    46501 gcgctttagc tactaggtgt aaggaagcag ggattgaacg ctttaccttt cacgctttta
    46561 gacacactca cgctagttta ttgctgaacg ctggtattag ttataaggaa cttcagtacc
    46621 gtctaggaca tgcgaatatc agcatgactt tggataccta tggccatctt tctaaggaca
    46681 aagaaaaaga agctgtttta tattatgaaa aggctatgaa taatttataa gtccacaaaa
    46741 aagtccacaa attaatattt tgagaggtgt aaacctaatg aaaccttgtt atatcaacgt
    46801 ttagaaagtg ttaaaaacaa aattatgaca aacattattg aattaccgga agttctcgcc
    46861 aaccaaattg cagctggtga agttgtagaa aggccagcga gtgttgtcaa ggaattggtt
    46921 gagaatgcta ttgatgctaa aagtagccag attaccgttg aaattgaaga gtctggcctt
    46981 aagatgatac aggttacaga caacggtgag ggaatgtctc atgaagattt aactttaagt
    47041 ctgcgtcgcc acgctactag taaaattaag agtcagagtg atttgtttag aattagaaca
    47101 cttggcttcc gtggagaggc tttaccgtct gttgcctcta tcagtaaaat cacgataaaa
    47161 acagcaacaa aagaagtcac tcacggttct cttcttatag ctactggtgg ggaaattgag
    47221 acacttgaag cgatctcaac tcctactgga accaaaatta aggttgaaaa ccttttttac
    47281 aacacgcctg ctcgtctcaa atacatgaaa agtttacagg cagaattagc tcacattgta
    47341 gatgtggtca accggttgag tttggcacat ccagaagttg ctttcacact gattagtgat
    47401 ggtcgccaat taactcagac atcaggaact ggcgatttac gccaagcaat tgcagggatt
    47461 tatggtttga atactaccaa aaaaatgctg gctatctcta atgctgattt ggattttgaa
    47521 gtttccggct atgttagctt gccagagttg acacgcgcca accgtaatta catgacgatt
    47581 ttggttaatg ggcgttacat caagaatttc ttgcttaatc gagcaattct tgatggttac
    47641 ggttctaagc tcatggttgg acgtttccca attgttgtga ttgatattca gattgatccc
    47701 tatttggccg atgtcaatgt tcatcccaca aaacaagagg ttcgtatttc aaaagagcgt
    47761 gagttgatgg ctttaattag tacggcgatt tctgaaagtc ttaaggaaca agatttgatt
    47821 ccagatgctc tggaaaactt agccaaatca agcacacgac atttctctaa accagagcaa
    47881 acacaacttc ctttacagtc taggggactt tattatgatc ctcaaaagaa tgactttttt
    47941 gtcaaagagt cggctgtctc ggaaaaaata cctgaaactg atttttattc cggcgctgtt
    48001 gacaacagtg taaaggttga aaaagcagag ctgttgcccc actcagaaga agttatagga
    48061 ccttcttcgg ttaaacacgc aagtcgtccc cagaatatct ttaccgagac tgatcatcct
    48121 aatcttgact taaaaaacag acaaaagtta tctcaaatgc taacccgttt ggaaaatgaa
    48181 gaaaaatcag tatttcctga attggattat tttggtcaga tgcacggaac ttatctcttt
    48241 gctcagggaa aagatggttt atttataatt gaccaacacg ctgcccagga gcgggttaaa
    48301 tatgaatatt atcgtgataa gataggtgag gttgacagta gtttacagca attgttggtg
    48361 ccctatttgt ttgagttttc cggttcggat ttcattaact tacaggagaa aatggcactc
    48421 ttaaatgaag ttggtatctt cttagaagtt tatgggcaca atactttcat tttgagggag
    48481 catcctatct ggatgaaaga agaagagatt gcatctggtg tctatgaaat gtgtgacatg
    48541 ttacttctaa ccaatgaggt atctattaaa acttaccgag cagagttagc tattatgatg
    48601 agttgtaaac gatctatcaa ggcaaatcat agcttggatg attattcagc aagaaatctg
    48661 ctactgcaat tggcccaatg tcaaaatcct tataactgcc ctcatggtag acccgtattg
    48721 attaatttta gtaaggcaga tatggaaaaa atgttccgtc gaattcaaga aaatcacact
    48781 agcctgcgag agctaggaaa atattagaga ggatgagatg caagagtttt taaaccttcc
    48841 taagcagatt cagctgaggc aactggtacg ctttgtgacc attaccttag gtagtagtat
    48901 ctttcccttt atggccatgt attatacgac ttactttggt acgttttgga caggcctctt
    48961 aatgatgatt accagtttga tgggatttgt tggaacttta tacggtgggc atttgtcaga
    49021 tgctcttggt cgcaaaaaag tcattatgat tgggtcagta ggaacaacgc taggctggtt
    49081 tttgactatt ttagctaatt tgcctaatgc ggctattcct tggttaacct ttgcgggtat
    49141 tttattggta gagattgctt ctagttttta tggtcctgcc tatgaagcta tgttgattga
    49201 tttgactgat gagagtaatc gtcgatttgt ttacaccatc aattattggt ttatcaatat
    49261 tgccgtcatg tttggtgcag ggctatctgg gcttttttat gatcatcatt ttttagcctt
    49321 gttagtagct ttattactcg tcaatgtact ttgttttggc gttgcttact actattttga
    49381 tgagactaga ccagagacac atgcttttga tcatggaaaa ggcttgctgg atagttttcg
    49441 aaattatcgt caggtgtttc atgatcgtgc ctttgtcttg tttaccttag gtgccatctt
    49501 ttctggtagt atctggatgc agatggataa ctatgtgcca gtccatttga aactgtattt
    49561 tcagccaacg gctgtgttag gtttccaagt aactagttct aaaatgttat cattaatggt
    49621 tttaactaat acattgctga ttgtcctttt catgacagta gtaaataaat taacggaaaa
    49681 atggaaacta ttacctcagc ttgtggttgg ttctttacta tttactctag ggatgctctt
    49741 ggcatttacc tttacgcagc tctatgctat ctggttatca gttgttttgt taacttttgg
    49801 ggaaatgata aatgttcctg ctagtcaagt cctacgtgct gatatgatgg atcattccca
    49861 aataggatct tatacaggtt ttgtgtcaat ggcacaaccc ctaggtgcta ttttggctag
    49921 tctcctagta tctgtcagcc attttacagg tcctttaggc gtgcaatgct tatttgtagt
    49981 cattgctttg ctagggattt attttacggt tgtttctgca aaaatgaaaa aggtgtaata
    50041 tgtacgatta tattaaaggt caattgacca aaattacggc aaaatacatt gtcgttgaag
    50101 ctaatggatt gggctacatg attaatgttg ccaatcctta tagctttaca gatagtgtca
    50161 accaattggt aaccatttat ctgcatcaag tgattcgtga ggatgctcac ctgttgtttg
    50221 gttttcacac ggaagatgaa aaagatgttt ttctgaaatt aatttctgta tcaggtattg
    50281 gtccgacaac agctcttgct attgtggcag ttgatgataa tgagggactt gtgaatgcca
    50341 ttgataacag tgacattaag tacctaatga aatttcctaa aattggtaaa aaaacagcgc
    50401 agcaaatggt tcttgactta gctggcaaat ttgtggaggc tccacaagag actggtcata
    50461 ccaaagcgcg cagcaataaa gcaggcaata ctcaactgga cgaagcgatt gaagccctcc
    50521 ttgccctcgg ttataaagca aaagagctga aaaaaattcg tgccttcttt gaggggacct
    50581 ctgagacggc agagcaatac atcaaatcag cattgaaact gttaatgaaa gggtaggtgt
    50641 ttcacatgaa acgttgctca tgggttccta aggataacca gctttactgt gattaccacg
    50701 atttagaatg gggtcaaccc ctacatgatg atagagattt ttttgaatta ctctgccttg
    50761 aaagttacca gtcaggctta tcctggctga ctgttttgaa aaaacgccaa gctttcagaa
    50821 ctgtttttca tcattacgac attgcatcgg ttgcaacctt tacctcggag gaactggctg
    50881 acgctttaga gaatccatcc atcattcgcc acaagctaaa gctagcagca actgtcaaca
    50941 atgctatcgc agtacagaaa attcaagaag agtttggtag tttttcaact tatctctgga
    51001 attttgttgg gggaaagcca attaacaacc ttgtcaatca agagaatctt gttcctgctc
    51061 aaacagaatt atctattcgc ttagctaagg atttaaagaa aagaggattt aaatttttag
    51121 ggcctacaac ggtttattct tttatgcaag catcgggtct ggtaaatgac catgaagagg
    51181 cttgtgtttt caatagaatc ttctaattct tcgtgaattg gaagattttt tgataaaatg
    51241 agatcagatt acgaatagat aagtaggtgg ggaaatgaaa gctgaactga ttgcagtagg
    51301 taccgaaatt ttgactggtc aaattgtgaa taccaatgct caatttctgt cggaaaaaat
    51361 ggcagagcta ggtattgatg tctattttca aacggctgtt ggggacaacg aggagcgttt
    51421 actttcagtg attacaactg ctagtcagcg gagtgatttg gtcattttat gcggtggcct
    51481 tggtccaacg aaagatgatt taaccaaaca aactttagca aagtacctta ggagagactt
    51541 ggtttatgat gagcaagctt gtcagaaact agatgacttt tttgctaagc gcaagccttc
    51601 atcacggaca ccaaataatg agcgacaggc acaagtgatt gaaggatcaa tccctttgcc
    51661 aaataaaact ggtcttgcgg ttggtgggtt cattacagtc gatggtatta gttatgttgt
    51721 cttaccgggt cctccaagtg aattgaagcc gatagtaaat gaagaattgg taccacttct
    51781 gtcaaaacaa tacagtacat tgtattcaaa ggtactacgc ttttttggta ttggggaaag
    51841 tcagttggta acagtcttgt cagattttat tgagaatcaa actgatccaa ccattgctcc
    51901 gtatgctaag actggcgaag tgactcttcg cttatcaaca aaaactgaaa accaagctct
    51961 ggcagataaa aagttaggtc agctagaagc gcagctacta tcccgaaaaa ctcttgaagg
    52021 tcaaccctta gctgatgtct tttatggcta tggggaggat aattccttag cgcgtgagac
    52081 atttgagctc ttagtaaaat atgataagac aattacagca gcagaaagtc taaccgcggg
    52141 attatttcag tcaactttgg cgagttttcc aggagcttct caagtattca atggaggctt
    52201 tgtggcttat agcatggaag aaaaagcgaa aatgctaggc cttcctttag aggagttgaa
    52261 atcgcatggc gttgttagtg cttatacagc cgaggggatg gcggagcaag caaggttatt
    52321 gactggtgct gatattgggg taagtttaac aggtgttgcc ggaccagata tgttggagga
    52381 acagcctgca ggtacagttt tcattggcct tgccactcaa aataaggtag aatcaataaa
    52441 ggttttgatt agcgggcgaa gtcgtttgga tgtgcgctat atcgccactt tacatgcctt
    52501 taatatggtc cgtaaaactt tattaaaact tgagaatttg ctataatgtt atttagtagc
    52561 tatagtagga tatggtttac aattatgtag attaatcctg ctgacgatgg tttgttaaaa
    52621 aagaggagaa agtattggca aaaaaattaa aaaagaatga agaaatcact aagaagtttg
    52681 gcgacgaacg tcgcaaagcc cttgatgatg ctttgaaaaa tattgaaaaa gattttggta
    52741 agggcgcagt gatgcgatta ggagaacgtg cagagcaaaa agttcaggtt atgagttcag
    52801 gaagtctagc tcttgatatt gcgcttggag ctggtggtta tcctaaagga cgtatcatcg
    52861 aaatctatgg tccagagtct tccggtaaaa cgactgtggc tttacatgct gtagcacaag
    52921 ctcaaaaaga aggtggaatc gcagccttta tcgatgccga gcatgcgctt gatccagctt
    52981 atgctgctgc gcttggggtt aatattgatg aactcctctt gtctcaacca gattctggag
    53041 aacaaggact tgaaattgca ggtaaattga ttgattctgg tgcggttgat ctggttgttg
    53101 tcgattcagt agcagcttta gtgccacgtg ctgaaattga tggtgatatt ggcgatagcc
    53161 atgtcggatt gcaagcacgt atgatgagtc aggccatgcg taaattatca gcttctatta
    53221 ataaaacaaa aactatcgct atctttatta accaattgcg tgaaaaagtt ggtgtgatgt
    53281 ttggaaatcc tgaaacaaca ccaggtggtc gagctttgaa attctatgct tctgttcggc
    53341 tggatgtgcg tggaacaact caaattaaag gaactggtga ccaaaaagat agcagcattg
    53401 gtaaggagac caaaatcaag gttgttaaaa acaaggtcgc tccgccattt aaggtagcag
    53461 aagttgaaat catgtatggg gaaggtattt ctcgtacagg ggagcttgtg aaaattgctt
    53521 ctgatttgga cattatccaa aaagcaggtg cttggttctc ttataatggt gagaagattg
    53581 gccaaggttc tgaaaatgct aagcgttatt tggccgatca tccacaattg tttgatgaaa
    53641 tcgaccgtaa agtacgtgtt aaatttggtt tgcttgaaga aagcgaagaa gaatctgcta
    53701 tggcagtagc atcagaagaa accgatgatc ttgctttaga tttagataat ggtattgaaa
    53761 ttgaagatta aaaagagccc ttcagggctt tttaaaatgt atttttaaag gttagtagga
    53821 ctactgttca taggtgtgtg ggtgaataga aaccatcatt taaaaagatg tgagagagca
    53881 gaacttaggt taactgatat aaaattaaaa taactaataa ttcaagggaa tacaggtgaa
    53941 aaaccttatt ttactaagat aatatcttta aaattaaaaa aataggtcca aagacctata
    54001 tttatagata agaaactgtg ctacaataaa gctatcacga aatagaaagt gagtcagcaa
    54061 catgattaaa atttacacga tttcaagttg tacgagctgc aagaaagcca aaacttggct
    54121 aaatgcccat aagcttgctt ataaagaaca gaacttagga aaagaaccgc taactaaaga
    54181 agaaatttta gcaattttat caaaaaccga aaatggagtg gagagcattg tttcatctaa
    54241 aaatcgttat gccaaagctc tcgattgcga tattgaagaa ttaagtgtta gtgaggttat
    54301 tgatttgatt caagataacc cgcgcatcct taaaagtccc attttgattg atgataaacg
    54361 tctgcaagta ggctacaaag aagacgatat tcgtgctttt ttacctcgct ctattcgtaa
    54421 tattgaaaat actgaagcac gattacgtgc tgcactctaa aagctcttgt agagcttttt
    54481 tttaaatacc ttcttcgctt gaaattcttg tttatttaat agaaataagc tataataaag
    54541 catagcactt aattttagaa agaaggtgta agtatgggat ttacagatga aacagtccgc
    54601 tttaagttgg atgatggcga caaacgacaa attagtgaaa cattaacagc agtctatcat
    54661 tcacttgatg aaaagggtta taatccaatt aatcaaattg ttggttatgt cttgagtggg
    54721 gacccagctt atgttcctcg ttataatgat gctcgaaatc agattcgtaa atatgaacgt
    54781 gatgaaattg tagaagaact tgttcgctac tatttacaag gaaatggaat tgatgttaaa
    54841 tgagaataat gggacttgat gttggctcga aaacggttgg tgtagctatt agtgatcctc
    54901 ttggctttac agcccaagga cttgaaatta tcaagattga tgaggaaaaa gcagaatttg
    54961 gctttacacg tttagaagag cttgttaagc agtaccaagt tgaacagttt gttattggat
    55021 tgccaaaaaa tatgaataac accaatggtc cacgtgttga tgcaagtata acttatggaa
    55081 accacataga gcacctcttt ggacttccag tccattatca agatgaacga ttgacgactg
    55141 ttgaggcaga gcgtatgctt attgagcaag ctgacattag tcgtggtaag cgaaaaaaag
    55201 tcattgataa attagctgca caactcattt tacagaacta tttaaatcgg aatttttaag
    55261 gagataaaaa atgacacata atcatgagaa tgaccaccaa cacgaagtta tcacacttgt
    55321 ggatgaacaa ggaaatgaaa ccttgtttga aattttatta acaattgacg gtcgtgaaga
    55381 gtttggtaaa aattatgttc tcttggttcc agcgggatct gaagaagatg agtctggtga
    55441 aattgaaatc caagcctatt catttactga aaatgaagat ggtactgaag gggatttaca
    55501 accgattcct gaggattcag atgctgaatg ggatatgatt gaagaggtat ttaatagttt
    55561 tctagatgag aactaaattg ttagtgacac tatgttaaaa agtagccgtg agggctattt
    55621 ttttaatgtt attttcgaat aaataagcag gaggtgataa tgataaaaga attaaatgat
    55681 aaatttatta ataattgtaa ggctaaacct ttgcatagat ttagagaatt
//
LOCUS       DAUCXI010000007        53531 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.007, whole genome shotgun sequence.
ACCESSION   DAUCXI010000007 DAUCXI010000000
VERSION     DAUCXI010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53531
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.007"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            31..1017
                     /locus_tag="VGY43_000427"
     CDS             31..1017
                     /locus_tag="VGY43_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ4301644.1"
                     /translation="MKHPIRKTLVTLGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKR
                     DKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVNGPLVQENLYGMQVYSWNDNGKP
                     DQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
                     LYQHYYHKNQNIFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEI
                     PEYEDADPILSSWGLKRVGELWAYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFY
                     PDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQIIDAINKTP"
     gene            complement(1151..1501)
                     /gene="rbfA"
                     /locus_tag="VGY43_000428"
     CDS             complement(1151..1501)
                     /gene="rbfA"
                     /locus_tag="VGY43_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEQ4301645.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRDLDNKS"
     gene            complement(1707..4568)
                     /gene="infB"
                     /locus_tag="VGY43_000429"
     CDS             complement(1707..4568)
                     /gene="infB"
                     /locus_tag="VGY43_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEQ4301646.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNINAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVVEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            complement(4588..4890)
                     /locus_tag="VGY43_000430"
     CDS             complement(4588..4890)
                     /locus_tag="VGY43_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEQ4301647.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAIADAGFSKKMRTLME"
     gene            complement(4883..5179)
                     /locus_tag="VGY43_000431"
     CDS             complement(4883..5179)
                     /locus_tag="VGY43_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEQ4301648.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            complement(5195..6352)
                     /gene="nusA"
                     /locus_tag="VGY43_000432"
     CDS             complement(5195..6352)
                     /gene="nusA"
                     /locus_tag="VGY43_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEQ4301649.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATAVEELVVDDVMTAEKV"
     gene            complement(6527..7063)
                     /gene="rimP"
                     /locus_tag="VGY43_000433"
     CDS             complement(6527..7063)
                     /gene="rimP"
                     /locus_tag="VGY43_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEQ4301650.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            complement(7171..7257)
                     /locus_tag="VGY43_000434"
     tRNA            complement(7171..7257)
                     /locus_tag="VGY43_000434"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7221..7223),aa:Ser,seq:gga)
     gene            complement(7322..7957)
                     /gene="trmB"
                     /locus_tag="VGY43_000435"
     CDS             complement(7322..7957)
                     /gene="trmB"
                     /locus_tag="VGY43_000435"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEQ4301651.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            complement(7957..8748)
                     /locus_tag="VGY43_000436"
     CDS             complement(7957..8748)
                     /locus_tag="VGY43_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEQ4301652.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            complement(8812..9846)
                     /locus_tag="VGY43_000437"
     CDS             complement(8812..9846)
                     /locus_tag="VGY43_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4301653.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAVLLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNVLSFLRGLSFLMLIVNMLCCSSAPKALILIVGMVFIACIY
                     LPYKLKKIID"
     gene            complement(9849..10574)
                     /locus_tag="VGY43_000438"
     CDS             complement(9849..10574)
                     /locus_tag="VGY43_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301654.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            10646..11065
                     /locus_tag="VGY43_000439"
     CDS             10646..11065
                     /locus_tag="VGY43_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ4301655.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS"
     gene            11062..11418
                     /locus_tag="VGY43_000440"
     CDS             11062..11418
                     /locus_tag="VGY43_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEQ4301656.1"
                     /translation="MKVKTMIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQGDSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(11529..12812)
                     /locus_tag="VGY43_000441"
     CDS             complement(11529..12812)
                     /locus_tag="VGY43_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ4301657.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTGELSKTFKDF
                     STSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYE
                     NLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGSSYQSASTDQDSTASSH
                     TPTTPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(12821..13345)
                     /locus_tag="VGY43_000442"
     CDS             complement(12821..13345)
                     /locus_tag="VGY43_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ4301658.1"
                     /translation="MIQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATP
                     QELSDFLSRSRTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQAEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            complement(13320..13781)
                     /gene="tsaE"
                     /locus_tag="VGY43_000443"
     CDS             complement(13320..13781)
                     /gene="tsaE"
                     /locus_tag="VGY43_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEQ4301659.1"
                     /translation="MFYSENEYTLKAYGETLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHDSAKSRY"
     gene            complement(13935..15395)
                     /locus_tag="VGY43_000444"
     CDS             complement(13935..15395)
                     /locus_tag="VGY43_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEQ4301660.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSSVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFNSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            15659..16471
                     /locus_tag="VGY43_000445"
     CDS             15659..16471
                     /locus_tag="VGY43_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ4301661.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTG
                     RPYRMALGYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLKYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTRHED
                     KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNINKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
     gene            16823..17815
                     /gene="manX"
                     /locus_tag="VGY43_000446"
     CDS             16823..17815
                     /gene="manX"
                     /locus_tag="VGY43_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEQ4301662.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            17904..18713
                     /locus_tag="VGY43_000447"
     CDS             17904..18713
                     /locus_tag="VGY43_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEQ4301663.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAAAEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGVIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            18730..19641
                     /locus_tag="VGY43_000448"
     CDS             18730..19641
                     /locus_tag="VGY43_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ4301664.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            19755..20114
                     /locus_tag="VGY43_000449"
     CDS             19755..20114
                     /locus_tag="VGY43_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEQ4301665.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGMGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTTINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            20506..21783
                     /gene="serS"
                     /locus_tag="VGY43_000450"
     CDS             20506..21783
                     /gene="serS"
                     /locus_tag="VGY43_000450"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEQ4301666.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRALLVQ
                     SEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGETVISPK"
     gene            complement(22016..22786)
                     /locus_tag="VGY43_000451"
     CDS             complement(22016..22786)
                     /locus_tag="VGY43_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEQ4301667.1"
                     /translation="MTDVSRVLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(22783..23649)
                     /locus_tag="VGY43_000452"
     CDS             complement(22783..23649)
                     /locus_tag="VGY43_000452"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEQ4301668.1"
                     /translation="MALFRKKDKYIRITPNNFLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFTSIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            complement(23658..25022)
                     /locus_tag="VGY43_000453"
     CDS             complement(23658..25022)
                     /locus_tag="VGY43_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEQ4301669.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAY
                     GNIIHLGERDCSLQRNNQKVLEESPSIAIGNTLRHEMGQAAVRAAEAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAINQEDITITGH
                     SIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            complement(25054..25476)
                     /gene="fabZ"
                     /locus_tag="VGY43_000454"
     CDS             complement(25054..25476)
                     /gene="fabZ"
                     /locus_tag="VGY43_000454"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEQ4301670.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            complement(25473..25973)
                     /locus_tag="VGY43_000455"
     CDS             complement(25473..25973)
                     /locus_tag="VGY43_000455"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEQ4301671.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            complement(25975..27207)
                     /gene="fabF"
                     /locus_tag="VGY43_000456"
     CDS             complement(25975..27207)
                     /gene="fabF"
                     /locus_tag="VGY43_000456"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEQ4301672.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMIDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            complement(27222..27956)
                     /gene="fabG"
                     /locus_tag="VGY43_000457"
     CDS             complement(27222..27956)
                     /gene="fabG"
                     /locus_tag="VGY43_000457"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEQ4301673.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPMKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            complement(27946..28884)
                     /gene="fabD"
                     /locus_tag="VGY43_000458"
     CDS             complement(27946..28884)
                     /gene="fabD"
                     /locus_tag="VGY43_000458"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEQ4301674.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPAILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            complement(28909..29880)
                     /gene="fabK"
                     /locus_tag="VGY43_000459"
     CDS             complement(28909..29880)
                     /gene="fabK"
                     /locus_tag="VGY43_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEQ4301675.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAQRWQSVSIEK"
     gene            complement(30081..30305)
                     /locus_tag="VGY43_000460"
     CDS             complement(30081..30305)
                     /locus_tag="VGY43_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ4301676.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            complement(30366..31340)
                     /locus_tag="VGY43_000461"
     CDS             complement(30366..31340)
                     /locus_tag="VGY43_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEQ4301677.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVKI"
     gene            complement(31341..31775)
                     /locus_tag="VGY43_000462"
     CDS             complement(31341..31775)
                     /locus_tag="VGY43_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ4301678.1"
                     /translation="MEYDKINQYLVDIFNRILVIEEMSLKTSQFSDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            complement(31852..32643)
                     /locus_tag="VGY43_000463"
     CDS             complement(31852..32643)
                     /locus_tag="VGY43_000463"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEQ4301679.1"
                     /translation="MQFKHIIFDVVDDLATLTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGLDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
     gene            complement(32863..33999)
                     /gene="dnaJ"
                     /locus_tag="VGY43_000464"
     CDS             complement(32863..33999)
                     /gene="dnaJ"
                     /locus_tag="VGY43_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEQ4301680.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            complement(34280..36115)
                     /gene="dnaK"
                     /locus_tag="VGY43_000465"
     CDS             complement(34280..36115)
                     /gene="dnaK"
                     /locus_tag="VGY43_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEQ4301681.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETIISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAAQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            complement(36296..36868)
                     /gene="grpE"
                     /locus_tag="VGY43_000466"
     CDS             complement(36296..36868)
                     /gene="grpE"
                     /locus_tag="VGY43_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEQ4301682.1"
                     /translation="MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(36871..37905)
                     /gene="hrcA"
                     /locus_tag="VGY43_000467"
     CDS             complement(36871..37905)
                     /gene="hrcA"
                     /locus_tag="VGY43_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEQ4301683.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLE
                     DMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDNSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            complement(38040..38609)
                     /locus_tag="VGY43_000468"
     CDS             complement(38040..38609)
                     /locus_tag="VGY43_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ4301684.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQAA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            complement(38606..39349)
                     /locus_tag="VGY43_000469"
     CDS             complement(38606..39349)
                     /locus_tag="VGY43_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEQ4301685.1"
                     /translation="MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQ
                     KDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFL
                     AAAQAIDPQEHLISGYRSVAYQAELYQSYIKKEMANDPTLTQESAEALVQTYLQPPGA
                     SEHHTGLAIDISTVDTLNASDPSVSKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMAQHNLTLEEYIAALKEKR"
     gene            complement(39339..40046)
                     /locus_tag="VGY43_000470"
     CDS             complement(39339..40046)
                     /locus_tag="VGY43_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ4301686.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEIDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFLWLIDPDRDKQYIDNGSVTVVEFDDGQFTIKTIGDM
                     SYRYRGREIIEERSDEI"
     gene            complement(40438..40677)
                     /locus_tag="VGY43_000471"
     CDS             complement(40438..40677)
                     /locus_tag="VGY43_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ4301687.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            complement(40892..41107)
                     /locus_tag="VGY43_000472"
     CDS             complement(40892..41107)
                     /locus_tag="VGY43_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301688.1"
                     /translation="MIVADSNKLKYFVSEKKAVGLSQAAFLYVMLVTAYKKTIIYAKI
                     RLTGIALEPSGVSDGYLMNHHVCLHYY"
     gene            complement(41104..42543)
                     /gene="gatB"
                     /locus_tag="VGY43_000473"
     CDS             complement(41104..42543)
                     /gene="gatB"
                     /locus_tag="VGY43_000473"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEQ4301689.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSTYDASQLTATKALSDFFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLLD"
     gene            complement(42543..44009)
                     /gene="gatA"
                     /locus_tag="VGY43_000474"
     CDS             complement(42543..44009)
                     /gene="gatA"
                     /locus_tag="VGY43_000474"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEQ4301690.1"
                     /translation="MSFNHKTIEELHDLLVAKEISATELTQATLEDIKSREEAVGSFI
                     TVSEEVALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKEILTTAASKMLYNYEPIFN
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            complement(44009..44311)
                     /gene="gatC"
                     /locus_tag="VGY43_000475"
     CDS             complement(44009..44311)
                     /gene="gatC"
                     /locus_tag="VGY43_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEQ4301691.1"
                     /translation="MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            complement(44543..44791)
                     /locus_tag="VGY43_000476"
     CDS             complement(44543..44791)
                     /locus_tag="VGY43_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEQ4301692.1"
                     /translation="MIRSRSRPLIRKGLAVSLARSVKPELKLGICGEHGGDPASIAFC
                     HSQGLTYVSCSPFRVPLTRLAAAQAAIKASGHSLTQDK"
     gene            complement(45306..45860)
                     /locus_tag="VGY43_000477"
     CDS             complement(45306..45860)
                     /locus_tag="VGY43_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEQ4301693.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDPWHPESKLFAAHNIKGTTGRHLYGPLAEVYSHMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            complement(46007..46789)
                     /gene="codY"
                     /locus_tag="VGY43_000478"
     CDS             complement(46007..46789)
                     /gene="codY"
                     /locus_tag="VGY43_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEQ4301694.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            complement(47007..48221)
                     /locus_tag="VGY43_000479"
     CDS             complement(47007..48221)
                     /locus_tag="VGY43_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ4301695.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            48452..48904
                     /locus_tag="VGY43_000480"
     CDS             48452..48904
                     /locus_tag="VGY43_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEQ4301696.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDDFEKQAQIAGITNIKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            complement(49026..50414)
                     /locus_tag="VGY43_000481"
     CDS             complement(49026..50414)
                     /locus_tag="VGY43_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ4301697.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGVAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDVEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            50486..51451
                     /locus_tag="VGY43_000482"
     CDS             50486..51451
                     /locus_tag="VGY43_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEQ4301698.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQDIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFNLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVVLVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(51800..52504)
                     /locus_tag="VGY43_000483"
     CDS             complement(51800..52504)
                     /locus_tag="VGY43_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4301699.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYFLGNVFLFSKRELK"
     gene            complement(52517..53419)
                     /locus_tag="VGY43_000484"
     CDS             complement(52517..53419)
                     /locus_tag="VGY43_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301700.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
BASE COUNT        16170 a        11479 c         9273 g        16609 t
ORIGIN      
        1 aaaaataaca tttacattaa ggagataccc ttgaaacatc ctattcgaaa aacacttgtc
       61 accttaggtc tattactgac cttatgcctg ccgactccag ttgcagctag ttctcgttct
      121 tggaagagct ggtttatcga gcaatatttc tggttaaaac gtgacaagag ttactattct
      181 aaacaagatg acccaagctt ccaaagatac cttgatgcct gtcgtgaaca atctgataaa
      241 ccttatcaac tagatactaa tttagtcaat ggtccccttg ttcaagaaaa tctttatggc
      301 atgcaggttt actcttggaa tgataatgga aaacctgatc aaaaaacaat tatttatctt
      361 gccggtggtt cttatcttaa caatccaacg acataccata ttaatatgtt aaagacatta
      421 tccacaagtc ttgacgctaa aattgtttta cccatttatc ctaaagcccc acgttatacc
      481 tataactata ctatgccaaa attggtcaat ctttaccaac actattacca taaaaatcag
      541 aatattttcc ttatgggaga ttcagcaggt ggaggtttag ccttaggtct agctcatgcc
      601 ctacacaatg aatcagtccc tcaaccaaag cagctcgttc ttttatcacc ttggttagat
      661 gttactatgt cacacccaga gattccagaa tacgaagatg ctgatcctat tctatcttct
      721 tggggattaa aacgagtggg agaattgtgg gcttactctg ctgataatac caaccatatt
      781 tatgtcagtc ctaaaaatgg tccgatcact tatctaccac caattacttt atttactggg
      841 acacgagaga tcttttatcc tgatattcgc gattatgccg caaaactgaa agccgctaac
      901 cacaatatta ccttcattac ccaagaaggc atgaaccacg tttacccaat ttatcctatc
      961 gaagaggcaa aaacagctca ataccaaatc attgatgcca tcaacaaaac tccttaatga
     1021 ggggaataac tcctacctgc caccagttaa tctggtggtt tttttgtagt ttgcaccaca
     1081 aaataacaat taaaaagagc cctatcataa tgataaggct ctttctgtca taacatccgc
     1141 accgcaatac ttaggatttg ttgtcaagat ctcgtaagag ttgatcaatt ttattaccat
     1201 aggcgatgga attgtctttt tcaaacacca aatctggaat tttgtacatg gtcaattgtt
     1261 tgccaagttc acgtttaatc gttccagtcg ctttttcaag ccctgtttgt gctttttgat
     1321 tatcagatgc caagtcactc ataatagtgt aataaacttt agcaagtgac aagtcaccct
     1381 gcatttgcac ttctgtaatc gttactccct gaacgcgtgg atcacgcact tttttctgaa
     1441 gaatatcatt tacttcgcgc ttgatttcca tcccaacgcg gtcaatacga tgattagcca
     1501 tagccatttc ctttccacat ttttaaaaca aaagctaggc tgaaagccca gcttatgaca
     1561 ttgttacctg ttttgatagc gacaattaaa gggaatctga gaattccatg acgagactgg
     1621 aaggaatgcc ccaagtagct catctggtag aaaaagtcat tatttccgac agaggaaaaa
     1681 cgttacatct cagaccttct tagcccctat tttctcacaa tttcttccat aatataggct
     1741 tcaatagtat cgtcaacttt aagatcgtta aagttttcaa tcatcaaccc accttcttga
     1801 gcattaccga cttctttaac gtcatctttg taatgtttca agctggccag tttaccatca
     1861 aaaataacga cactatcacg gataacacga acactcgaat cacgtgtcac cttaccgttg
     1921 attaccataa agccaccaat tgttcccact ttagaaactt tgaaggtttc acgaataatg
     1981 gcttcaccaa gaattttttc ttggtaaaca gggtcaagtt tccctttcat ggcttcttct
     2041 acttcttcaa tgactttata gataatgcta tgaagacgaa tttccacatc atccgtatct
     2101 gcttgttgac gagcttgtgg ggtagggcga acgttgaaac cgataataac agcatttgat
     2161 gcttcagcaa gggtcacatc agactcattg atagcaccta cagcagagtg aacgacattg
     2221 acacggacac cttccacttc aatctttaca agagatgctg caagggcttc aacagaacct
     2281 tgaacgtctg ctttgatgat gacattaaca gtcttgattt ctcctgcttt aagggtatca
     2341 aagagattat caaggctaac acgctgtgta ttttgacgtt gtttgaggag ggcacgtttt
     2401 gatcgctcct caccagctgc acgcgcagct ttttcatcag cgtaaacagc aaagtgatca
     2461 ccagccattg gtgtttcgtt caaaccagta atggaaactg gtgttgatgg ctccgcagat
     2521 ttaacacgac gcccaaggtc atttaccatg gcacggacac gaccaaaggt attaccaaca
     2581 acgattgggt cttgaacatg aagagttcct tgttggacaa gaagtgtagc aatagcacct
     2641 ttacctttat ctaagcgtgc ttcaatcaca gtaccaatag cacgaaccgt tggatcagct
     2701 ttcaattctt ctacttcagc aaccaaaagg actgtttcta atagttcatc aatattttta
     2761 ttaaatttag cagatatctc tacaaattcg cactctccgc cccaagcagt tgagatgata
     2821 ccatattctg ccaattctgc gataacacgt tctggattag cacctggttt atcaattttg
     2881 ttgatagcaa caataattgg aacaccagca gcttttgagt gattgatcgc ttcaatcgtt
     2941 tgtggcataa caccatcatc agctgcaaca atcaaaatgg tgatatcggt aacggaagct
     3001 ccacgtgcgc gcatgcttgt aaaggccgcg tgtccgggag tatccaagaa ggtaattttc
     3061 ttgccagctt cttcaatctg gtaagcacca atatgctgag taattcctcc agcttctcct
     3121 gttgccacac gtgagttacg caaagtatca agcaaagttg tcttaccgtg gtctacgtgt
     3181 cccatgatag ttacaacagg tgcgcgttct acaatatttt caggattgag gtaattttca
     3241 tcctcaaaga agcgctcgat atcagcatca tctacttcta ccttagcctt agcctcaata
     3301 ccataatcta ccatcaataa ttcgatagta tccccatcta aagactggtt ttgagttgcc
     3361 ataacaccca tcataaacag ctttttaaca atttcagcgg gttcgcgttt gatacgtttt
     3421 gcgatttcga caactgtcat gccttcagta tattcaaatt cttttggcaa ttcatggaat
     3481 ttacgctcgg ttactggttt tggagcggtg ttggtattct taacattttt gccttttttg
     3541 gtctttttat ttttattcca gttactattt ttttgatttc tcacttggtt ttgactattc
     3601 caactcttct tatttttctt ttgtccttct tgtgaatgat gagttaactc acgattcttt
     3661 tcaggacgtg cttgtttttt acggcgatta tcagcagtag atttagcatt aatatttgat
     3721 gactttaatt tagtttctgc ttcttcaata gatttcagtg ctgcttcacg atggctcatc
     3781 tcctcagctt gtgcttttag agccgcttct ttagcttctt gtcttgccaa ctcagctaaa
     3841 cgcttagctt cttgctgtgc acgaaaacgt gtttcacttt ggcgtgagta ttcagcattt
     3901 tgttcagctt ttaaggcagc agcacgagct ttgaaatcaa ttttaggact tttcgattga
     3961 ggctcttgtc gtccttgctt tttttggttt gtgaatcgac cattcttgtg attctcctta
     4021 gcaaaggaac ggttacgatc accaactagc tgatgattat catgtctagg tgatacattc
     4081 gatgcttttc gctcaatacg cttatcgttt gtatcacctt gagaacgatg agtaatcctc
     4141 ttatctcctt gttcgttagt ttgatgatta ttgggctggc gataacctcc tcgacgttct
     4201 tgagaacgat gagaagagcc atttgcttgt tttcgagcag cctgttcctt tgcacgagcc
     4261 tctctctcag ctttaaaatt acgactcttt ggcttagaga cctgtgtttt ctctacatgc
     4321 tcagaacctg tttctttgac cactgttaca gagggttgag caacttcttt gggtttgact
     4381 gtttgagaag ctgtcacatc aggtttagaa gcctttgaaa aacttgaaat aatctttttc
     4441 gcatccgctt cttcaacact tgatgcatgg cttttcacat ctaatcctaa gtatttagcg
     4501 tgttcaacca cctctttact acttttacca atttccttgg caatttcatg taatcttttt
     4561 tttgacaatt tgtgtcctcc tattcatcta ttccataaga gtcctcattt tctttgaaaa
     4621 tccagcatct gcaatggcag caaccttcct tggtttacct agtgcagcac ttaattccag
     4681 tgcattcaac actgtggaga cttctacatt ataataatta cttttatctg ttactttttt
     4741 tgtcacatta ggaccagcat cattggctaa aaatactaat attacctgct ggtgttgaat
     4801 agcttttact actagttctt cacctgaaat cacttttcca gcccgttgag ctagaccaat
     4861 aagactagat aatctttcta aattagtcaa gacctaactc tcttcttttg attttgtgat
     4921 caacataagc aatcaagtca tcgtaaaaac tttctggaat gtccattgag aaactcctgt
     4981 tgaaaacttg ttttttcttg gccattaagg cctcttgatt gtctaatttg atataagcac
     5041 cacgaccatt ttgtttacca gttggatcaa tgaaaacttg accatcctta gtttttacaa
     5101 tcctaagaag atctcgttta gcaataattt caccagaaac aagtgatttt cgtaaaggta
     5161 tttttttgac tttagacatc aaacacctct tttcttatac tttctcggca gtcataacat
     5221 cgtcaacaac tagctcttcc acagctgttg ctgcttcttt ttccgcctca agacgatcat
     5281 attcgctagc tgatttgata tcaatacggt agccagtcaa atgtgccgct aaacgaacat
     5341 tttggccgcg acgcccgata gctaatgata atttgctatc aggaactact accgtagcac
     5401 gtttaagatc ttcatcgtca aaaagtacca tgtctacttc agccggagca atggcattgt
     5461 agatgaactc agctggatca tctacccatt gaatcacgtc aatattttct tcaactggaa
     5521 tttcaagccc cgtcttagca tctacacgtt ttggatggaa cttgctgatg acctttttaa
     5581 tattacttcc accacgtcca acaattgttc cgatggcatc aacgttagga ttatgactgc
     5641 gcacagcaac cttggtgcga tcacctgctt cacgagaaac actcatgatt tcaacagtac
     5701 catcaaagac ttcaggaatt tcttgctcca taatacgttt gatgaattct ggatggctac
     5761 gactaacaaa gacgttaact cctttaggat tattttcaac tttgtagaca taaacgtcaa
     5821 tacggtcatg tgatttgaaa gtttcacctg gaatctggtc ttggtgagac aattgtgctt
     5881 ctaaggaacc aagattgaca taaataaaac gttgatcaaa ccgttcaact gttcctgtca
     5941 taatttcacc ttcatgctct ttgtattcat tgaacatcac ttcacgcatt tggcggcgca
     6001 tcttttccat aatagtctgt ttagctgatt gagctgcgac acgtccaaat tcattgacag
     6061 attcttcaaa gcgaatctta tcacccaatt cataggcaga actgatagca agagcatctt
     6121 tcaaactaat ctcaagccgg ctgtcaaaaa cttcctcaac aacctcacga accgtgaata
     6181 cttgaaaatc agctgttttt tcattaaatt caataacaca tgattctgat tgaccatagc
     6241 gacgtttata ggcagacttt aatgattctg tcactgcgtc aataatatct gctttatcaa
     6301 tgtgtttttc ttcttccaaa atacggaagg cttctagcat ttctttgctc ataatgttat
     6361 ctaccttgct tgtaaagctt ggcaaaaatc ctttcttaaa ttaatacgat caatagcccc
     6421 ctaaaggctc ccttaattcc ttttgtttag cttgtataaa ctctataggt gttgtttcaa
     6481 atttgcttaa gcgctcctaa aaaagtttag tgctttgaaa taaaagttat aatttgacag
     6541 ccattctcac cttagcaact gcttgatatg gtatattcac gatcttatga cgtgttttat
     6601 caagataatc aatggtcaac gtttcaccat caaaggctaa taagtctcct tgaaaaactt
     6661 tcaccttatc aatagcttga taaagactca cattgatata agagccaact gctgctttta
     6721 aactgtcagc tgtcttaagc ggacgctcca aacctggact agagacttct agcatatatt
     6781 ggtttggaaa aggatctgga tcaatcgtat ctaacagcgg actaataata ttcgtcaagt
     6841 cagatgtatc ttccactgtg attccacctt ccttatcgac taaaatacta aggatgtagt
     6901 cactacccat tttgtcatac tcaacgtcta ctaattcata aggtgcctta atctcaggcg
     6961 ttactgtctt ggttacgata tcgataatag atgtatttgc tattttgatt acctcctcta
     7021 tttttatgct cttctctaag ataattggtc cttgggaatc cacttaatac aaaagtggcg
     7081 agacatatcc caccaccttt ctgtattatt taagcctatt ataccataat ttaagaggaa
     7141 tgcaaggata tgcactttgt tttactcaca aggagaggag gggattcgaa cccccgagcc
     7201 ccgttaagga ctacacgctt tccaagcgtg cgcactaagc cactatgcga cctctccatt
     7261 actaaagaag ttaatactgt atcaactcct ttatgttatc atattttgaa acaaaatact
     7321 actagaaatt tgcctcaact cggtaaatga cttgaccttt attagagaac ttctcttcat
     7381 attctgtcat gacatttcct tcatagttac tagcgtgtaa gtcaagccag atctgtctca
     7441 aggtcatgcc gtattgagaa aaactagcta aactgtactc aaacaagccc cgattatcgg
     7501 ttttaaaatg aatttcaccg tgttctggta agatacgctt gtaagtgtct aagaaatcct
     7561 tgtaggtcaa acgacgtttt tcatgcttgg tttttggcca aggatctgaa aagttgaggt
     7621 acatcatatc cacctcacca tcttcaaaat agttggttaa acttgatcca tccactcgca
     7681 gaagtttgac attgggtact tctgaagcta ataccttatc caaggcgtag cttaggacag
     7741 ataattgaat atcaatgcca atgtagttaa tatcaggatt tttcaaggcc atccctgtga
     7801 taaatccgcc ctttcctgaa ccaacttcga tatgaatagg acggtcattt ccaaaaacgt
     7861 catgccaacg gcccttggca tcttctggat ttaatatcac atagtgtggg ttattagcta
     7921 agtgctcctc agcacctttt cgttttctaa ctcgcattat ttctttctaa atatttctct
     7981 aaattttctg agggcataaa tctcctgatt cacatgctcc atgtcacgct tgtcaaaaca
     8041 cttgagaatt tgtgtcaggt gagaaaattg accataccaa ataatttttt gcataacctt
     8101 gtcattattt ttatagccat aataagacag ccattctgac caacgagacc gtggaatata
     8161 gtggctcaac aggtaagcaa catcatacat ccgatcagtc agacgaacag aatcccaatc
     8221 tactaaaaaa atcataccgc tagtagtaat cacccaattg ctatgtttaa tatctccatg
     8281 cacaatcgtt gctacttctg atttgaactc tggtaagctc cgttttaatt ctttaacgat
     8341 agcttgtaag tatgaatttt gctgaatttg caagggtgca ttttgctcaa aatcaaccaa
     8401 taaatcgtat gggttttcaa tcttataatt gagctgaagc agttgattga ctaatttttt
     8461 agatttgtga aggcgcaata gaatatgaat gatttgctta ctgttcatat cttctttggt
     8521 caatgtacgg ccgttaagcc attcttgggc actcatcata tcaccattgc ccatgcgttt
     8581 ggcccaaagt aactgtggcg caatctgttc ttttgctaag gcaggtagaa taggggtcgt
     8641 atttaatttt ataaagacac attccccatt tggataagtg cctttataag ctttgccact
     8701 tttcccacgt aagggagtca aggtaagttc ttgttccgtc gttgtcacct tatcgccctc
     8761 cttttctatc ttttatagtc gtttacccct attttacttg ttttaggcta cttagtcaat
     8821 gatcttcttt aacttataag gtagatatat acaagctatg aaaaccatac ctacaatcaa
     8881 aatgagtgct tttggcgctg atgagcaaca cagcatattg acgattaaca ttaaaaagct
     8941 taaacctcgt aaaaaactta acacattttt cttcttgctc cgactatttt caggataaag
     9001 actagtcata taatggtaat cgtagtgata ataaagtgaa agtaattgga atacaactaa
     9061 atagttaaaa atgagtgcta aacttactga caaataaaga ttatggataa aaaatacaga
     9121 taatgagctt aatagcatta gccgtaaaaa taagcccaaa taatctgaac tacgtaaaaa
     9181 ggctctagca taaagggaca gccaaaggtt tgaaggagtt tgcttaacta attttaaaag
     9241 aggatttaga taagttcttt ctttcacttt tgtagaaatt cctttgactg ttgtaaaaag
     9301 agaataaaac tttaaaatac tttgcttgcg attgctttca aatgcgacag cttttgccca
     9361 atctaaacga tttcctctca aaaaatatct tgtctttcga ctaagcacta ctctttttag
     9421 tgccaataat atcaaaacta agataataaa aataaataaa gacagaccta gacgtctaaa
     9481 aataggatat aaaaagagca atacagcagt ctgcaaagtt ccccaaagca aaaaagagag
     9541 tcgttcagct tgtttgatat aagaaatcac ttcttcttct tttggaagta agaaatgctg
     9601 atctgcctct tctagatacg ttgctataga tcccatactg agcaataatg ggatcaatat
     9661 cccaagacaa acctgaatag gtagatgatt cgttggaaaa tggtttagta gctgaccata
     9721 ctgcaccata gcaaagccta ataaaaacat caacaccaaa acaaagtgat catttaagac
     9781 gtaacgaagg tatttatttt gctgtttttg aaagtcttga cggcgtttca gaaataatgc
     9841 tttcatactt aatcctcttt tgttaatgca agatagatat catttaagct cgctgaacgg
     9901 tcaccaaaag cttcttgcaa gtcagcaaga gttccttggg cacgaacttg tccatgatgc
     9961 aaaatcacaa aacgatcaca cattctttca gcagagtcca aaacatgtgt actcatcaaa
    10021 atagattttc cttttgcttt ttcgacttct agcgtttgga ttaagtctga aatagctaaa
    10081 gggtctaacc ctaagaatgg ttcatcaaga ataaatagac ttggatcaat gacaaaggca
    10141 caaataatca tgactttttg tttcatccct ttagaaaaat tgacaggaaa ccattcaagt
    10201 ttgtcagtta aacgaaacat ttccaagaaa ggttgtgctc gtttttgtgc cacttctaag
    10261 tcgatatcat aagccatagc tacggtgttg atatgctctg ataaggtcaa ttcttcatag
    10321 agactaggag tttctgggat aaaacctatt ttttgacggt aggcaactgc attttctgct
    10381 agagttaaac catcaataga aatacttcct tgataaggct tcaaaaagcc aataatttcg
    10441 ttgatagttg ttgactttcc agcaccattt agcccgatca aaccgactaa ctctccattg
    10501 tctacagaaa atgagacatc gtttaaaaca gggatattgt gatatcctcc tgttagattt
    10561 ttaatgttta acatataatt tctttctagt ttttgatata cttataatat attataacaa
    10621 attcaagtag agaaggtgat ataaaatgga aaattgtatt ttttgcagca tcattcaagg
    10681 ggatatcccc tcttcgaaag tctacgaaga tgagcaggtc ctcgcctttt tagatatctc
    10741 acaaactaca aaagggcata ctctagtcat tcctaagcaa catgttcgta acttactaga
    10801 gatgactgct gagacagcta gtcatctctt tgctcgtatt cctaaaattg ctcgtgctat
    10861 ccagtcagct actggcgcta ctgccatgaa tatcattaac aataacgaag ccttagcggg
    10921 acaaactgtt ttccatgctc atgttcatct cgttcctcgt tataatgaag aagacggtat
    10981 ctcaattcaa tacaccactc atgagcctga ctttcctgtc ttggaaaagc tcgcccgaca
    11041 aatcaatcag gaggttagtt catgaaagtt aaaaccatga tagccgtcgg attattatct
    11101 tttaccgctt acaaagcata tcaaaaacgt tgtaccataa aagagctatt atccatcagt
    11161 cgacaagcaa aggatgctgc acaacttgat ttagataaca ttaaagcaaa ccttgacctc
    11221 attcacagtc aaggaaaagt aattcaaaat attagtcagg acttggccca taaatggcgc
    11281 tactttaacc aagagacaca agcacacctc actgaaatcc aaaatcgtat ggccaaatat
    11341 caaggagata gtgagctaat ttctagtgaa tcacctactt gccaaaccgt cattttaact
    11401 aacaaccatt ccagatagta ttatctccct catatacttt atttgaaatc acagacagct
    11461 atcatctttg atacctgtct tttttatatt caaaatcgga tattttaaac ataaaaaccc
    11521 tcagaacgtt aggtctgagg gttgatatta gcaggaggaa ctaatgatcc agaccctgat
    11581 gagctagact catcagctgc taaagcatct gatgaagaag acggcgtagt tggcgtatgg
    11641 cttgaagcag tagagtcctg gtctgtacta gcactctgat aagatgagcc ggtatctact
    11701 ccacttgaat aattagcgta agagctatga ctatcagaat aagatggagc ctggcctgaa
    11761 gagtcatagt tgttgtttac tgtctgagac ttagttgacc catacaaatt ttcataaaca
    11821 gtagcatttg tttttaattg actaacctta tgaagtccta attctgttcg gatacgattt
    11881 tggatttcta acaaatgatt agaggtaaca atttggtatg atccaccatc tgataaagtg
    11941 gcatcttctc cttttagttg ataagtctta atagttctaa gtgcgtcacg ataacctaat
    12001 agactaggga tagtgcgaga agagatttcg atattcgttt gcatattact acttacagca
    12061 gataaaatct tccgataaga gctaatgcta tcaagagcaa ggattttttt caataccttt
    12121 tgaatgactt cacgttgacg cttttgtcga ccataatctc cctcaggatc atcataacgc
    12181 atacgagcat aaaccaaagc ttgttcaccg ttaattttgt gtgttccagg cgcaacagta
    12241 gcttgatatt caggttcgtt ttcagcaatc gagataggaa aatcaaactc atttgtaact
    12301 gtaatccctc caactgcatt cacaagatca ataaggcctt gcatattaat ttgaacatag
    12361 ttatcaatgg tgatattcaa aagatcttgc acggtcataa tagccatctg agcgccacct
    12421 gctgcataag cagcgttaag cttagcttca acaccattca tttcattatt tttgggtcca
    12481 gataacgtgg ttaaggtatc tcgttctaaa ctagtcatag ttgttttctt ggtctttgga
    12541 ttaaccgtaa ccaaaatcat cgaatcactg tttccttccc acttggaggc acgctctgaa
    12601 gagcctgtat caacacccat caacaagata gaaaaagctc ttgtttgttt aatggcatca
    12661 cttttctttg aagatgtcga aaaatcttta aaggtctttg ataattctcc tgttgagaag
    12721 gtataagcac tagttagata gacacctaat gccaagacag ttgttaacac aatagctgtg
    12781 aacattaaaa ctattttttt tccaattttc atcgattcac ttactgactt acagatttac
    12841 gcatatgata aacatctaag tcatctccat tttttgattt gatgtcgttt tttcgcatac
    12901 tttcaatacg aaaaccatac tttttataca ggtaaatagc cttagtattt cttacttgaa
    12961 cgtccaactt aaggctttcg atataagggt tttcttcagc ccaatcaaga gcaatctcta
    13021 acaataattg accgatacca taaccacggt aagtcttagc aactaacata aatacatctg
    13081 cttcagcttg gccttgggat aatacttccc cagaaagatt taaaagccct actacttttt
    13141 catctaatct agctagcagg caaaaatcaa taaaagaggt tcgacttctt gataaaaagt
    13201 ctgacaattc ttgaggagta gcctctaata tagtctctac gcctgttata aaatctgttt
    13261 ctttggcagc tgccgtcact aaggaaagta cagcttttgc atcttgaggt acgccttctt
    13321 caataacgag actttgctga atcatgtgac attatctcca gaagctgacg agagcgctca
    13381 ccatgcgcta acaagtctag ttgacgacct ttgtctcgtt tagtaatggt aatttgcaaa
    13441 tagtcttgta ataatccctc tcctaataat tctccccact caataacggt aacaccatta
    13501 ccaaaaagaa aatcatctaa atcaatagag tctggatcat caccaacacg gtaaatatct
    13561 aagtgataaa gaggtagacg tccttcatat tctctaacaa tagtataagt tgggcttttg
    13621 atcatttgac taatccccat ccctttagca ataccttttg ccaatgttgt tttaccggca
    13681 cctaagtcgc cagacaatac aatcacatct ccaatagaca aataagtacc tagggtttcg
    13741 ccgtaagctt taagagtata ttcattttca ctataaaaca tagcaacatt atatcagaaa
    13801 aaaaacatac ttccaagcac tacctagaag atgactcaaa taaggtattc gtaaagtaaa
    13861 aacgcttctt tatattaaag gttaaaatca attaaagaag cggcagttag tagcaaaata
    13921 agtaaattat ttggttataa gatagttaat atgatgaaat ttacaatgaa caagaaggtt
    13981 gctccccaaa taatagggtg aatatctttt gtttttccct caacaacttt tactagacaa
    14041 tagaaaataa aggcagcggc aataccatag gaaatagagt aacacagcgc cataaagaaa
    14101 gctgcaaaaa aagctggaag agcatctgca aatttactcc aattaacatc aagaaaagaa
    14161 gacaccatca tgacacccac aacaattaaa gctggagccg tagcagcagc cgggacaata
    14221 cctacaagcg gtaatagcaa tattgataat aagaagcata ctgcggtgga gactgctgtt
    14281 agtccagtac gtccaccttc agcaattcct gctgctgatt caacataggt agtcgtattt
    14341 gaagttccaa ccaaagcccc aatagaagta ccgatagcat ctgcaaaaag cgcacgatcc
    14401 atttttgaat taaagcctat actattttcc aaagcattct catcgtcttg agagaaaata
    14461 cctgttcgac gaccagttcc gataaaggta ccaattgtgt caaaagtatc tgatagacta
    14521 aaagcaaaaa tagtcatgaa aactagcggt aaacgacttg aatcgctaaa aagagaactc
    14581 aaaccatcga aagctgcaag gaaagttgta cctaattcag tccaagcttc accaatatgg
    14641 ctgatcccaa aattgaggtt ggacacatcc actattccta aaggaatacc tacaagagtt
    14701 gttgcgacaa taccaattaa aatagcacct ctaaaatttc gaatcacaag agctgtcgtt
    14761 aaaagtaaac caaaaatagc aagtaataca ctggaatccg taaaactaga aatcgtaggt
    14821 acaactccac cattggcgtc tacaaataat agaccatctg caaatgtttt agccgatgct
    14881 ttagccggtt caacaccatt taccattact atattttcag cagagataga aaaagtaatg
    14941 atatttgcat ttttaaatcc taaataagct acaaagacac caattccccc accaatagca
    15001 tgctgtaaac taactggaat cgccttgatg atacttttac gaaacttggt tacggtaata
    15061 aaaatattga ataatccaca aatgaaaacc attgccaagg cttcttgcca tgaaaaccct
    15121 aaagcaaaaa caactgtata agtgaaaaaa gcgttaagtc ccattcctgg tgccaacgca
    15181 taaggcacat tggcaaataa tcccataatt aaggttgata tggctgctgc gataatcgta
    15241 gccaaaaaga cagcattaga gggcatcccc gctgcaccta aaatacttgg gttaacaaac
    15301 aaaatatagg acatggcaaa aaaggtcgtt aaaccagcca taatctcagt tgagacagtt
    15361 gtcccatttt cgcttaactt aaaaaacttt tccattgaaa tggagtctcc ttaattaaat
    15421 agtaggtaaa atcaaaaagc gcttatcact agataagtct ttttgacacc tcattattat
    15481 tgttattgtt cgtattaaaa tgaacaataa cactatgtta ccattttttt gttcactttt
    15541 caacgtctat accttcattt attcattaaa aaaacagtta tcctatcttt tttactaatg
    15601 aatacgctta acttatcttt tctctttatc ttggagcaaa atttgctata atctaattat
    15661 gactaaaaaa ttgattgcca ttgatttgga tggaactttg ttacatcatg acaacaccat
    15721 ctctacctat actcaaaaaa ccatcaaagc tgtccaagac aagggccacc acgtcattat
    15781 ttcaacaggc cgtccttacc gcatggcact gggctactat ctgcagctca atttaaagac
    15841 cccaatcatc acttttaatg gggccttgac ccacatgcct gaacaaaaat gggcctatga
    15901 acataatgtc actttggaca aaggctacct actaaggtta ctaaaatatc aggatgattt
    15961 ccagatggat tttattgcca gtgagtatcg aaaaaatgtc tacatcacca tgaccaatcc
    16021 agaaagtatc gacccgcaac tctttggtgt tgatgaaatt actcaggaca tggcattaga
    16081 gattaccaaa atcactcgaa atccaaacgc cttattgatg caaacgcgcc acgaagacaa
    16141 gtatgcctta gctaaaaaca tgcgtgcttt cttcaaagat gaaattgaaa ttgattcttg
    16201 gggaggccct ctcaacattc ttgaaatttc gtctaagaat atcaataaag cttacgctct
    16261 gaactatctc cttggaattt acaatatgga taaaaaggat ttaatcgcct ttggtgatga
    16321 acacaatgac actgagatgc tagcttttgc tggaactggt tatgccatga aaaatgctag
    16381 ccctgtgcta ctgccttatg ctgatcagca gcttaatttt tccaacgaag aagacggtgt
    16441 tgccaaaaaa ttggaagaac ttttcttata gtagcaaacg aaaccactat ttttcagaaa
    16501 atggtggttt ttcttctgtc aacagctatc aaaaaatgaa aatcatttta ataatttcaa
    16561 catttttcag catatttttg ttttaaacag cttaaaaaca cctttaatat caataatctg
    16621 cctattcaat cctaaattct gaaaattttt tcatgttttg tactattttt ccgaaagggc
    16681 ttgatttttt agtgaaaacg ttttaaaata gaaacgttct tgaatttcgt ttaagtgaaa
    16741 aagaattgcc aaaatttagt tttggaagga gattattctt cttcatttca acgaaaaata
    16801 ttttaaagga ggaagaacaa gaatgggtat cggtattatt attgccagcc atggtaaatt
    16861 tgctgaaggt attcatcaat ctggttctat gatttttggt gaacaagaga aagttcaagt
    16921 tgttactttc atgccaaacg aaggaccaga tgatttgtat ggacacttca acaatgctat
    16981 ccaacaattt gatgctgatg atgaaatcct tgtgctagct gacctttgga gtggttctcc
    17041 atttaaccaa gctagtcgtg tggcaggtga aaatcctgac cgcaaaatgg cgatcatcac
    17101 tggtctcaac ttgcctatgc ttattcaagc ttacactgaa cgtcttatgg atgctggtgc
    17161 aggtgttgaa caagttgctg caaacatcat taaggaatct aaggacggta tcaaagccct
    17221 tcctgaagac cttaacccag ttgaagaaac tgctgcaact gaaaaagttg ttaacgcact
    17281 tcaaggagct attcctgctg gaactgtcat cggagatggt aaattaaaga tcaatcttgc
    17341 tcgtgttgac actcgtcttt tacacggtca agttgcaaca gcatggactc cagcttctaa
    17401 ggctgaccgt atcattgttg cttctgatga ggttgctcaa gatgaccttc gcaaacaatt
    17461 gatcaaacag gctgcacctg gtggtgtcaa agctaacgtt gttccaatta gcaaattgat
    17521 tgaagcttct aaagatcctc gttttggtaa cacacacgca cttattcttt tccaaacccc
    17581 tcaagatgcc cttcgcgcgg ttgaaggtgg tgttgaaatc aacgaattga acgttggttc
    17641 aatggctcac tcaactggta aaacaatggt taacaacgtt ttatcaatgg acaaagaaga
    17701 cgttgctact tttgaaaaat tacgcgacct aggtgttaca ttcgacgtcc gtaaagttcc
    17761 taacgattct aagaaaaact tatttgagct tatccaaaaa gctaacatta aataagtttc
    17821 aaacgctata aggttttaaa acgatgacta gctaacttat tagcaaaaag tcctcgttta
    17881 ctatactttg aaaggattac aacatgtcag atatttcgat tatttctgca attttggtcg
    17941 ttatcattgc cttcttcgct ggtcttgaag gtatcctcga ccaatttcaa atgcaccaac
    18001 cacttgttgc ctgtactttg attggacttg taactggaca ccttgaagct ggtgtcatcc
    18061 ttggtggtac acttcaaatg cttgctcttg gttgggcaaa catcggtgct gccgttgccc
    18121 ctgatgctgc ccttgcctct gttgcagctg ctatcatcat ggtcaaaagt ggcgacttta
    18181 ctcaaaaagg aattaccttt gcttactcaa cagctatccc acttgctgtt gctggtcttt
    18241 tccttacaat gatcgttcgt actttgtcaa ctgcccttgt acacgctggt gacaaagctg
    18301 ccgctgaagg taatttcgca ggtattgaac gcttccactt tattgccctt cttcttcaag
    18361 gattgcgtat cgctgtccca gcagctcttc ttgttgctgt tcctacttca gccgtacaat
    18421 ctgttttgaa tgctatgcca aactggttga acgaaggtat gcaaatcggt ggtgcgatgg
    18481 ttgttgctgt aggttatgct atggttatca acatgatggc tactcgtgaa gtatggccat
    18541 tcttcgccct aggttttgct cttgcagcta tcagccaatt aacccttatc gctatgggtg
    18601 ttatcggtgt agcaattgcc ttcatctacc ttaatctttc taaaaagggg ggtaacggtg
    18661 gtaatgcagc aggttcagct gatccaatcg gcgacatctt agaagactac tagaaagggg
    18721 taagaacaaa tgactgaaca aattaaatta actaaatcag accgtcaacg tgtttggtgg
    18781 cgttcacaat tcttacaagg ttcttggaac tacgaacgta tgcaaaacat gggctgggct
    18841 tatgcactta tccctgctct taaaaaattg tatacgtctc ctgaagaccg tgcagctgct
    18901 cttgagcgcc acatggaatt ctttaacact cacccatacg ttgcagctcc aatcattggt
    18961 gtaacacttg cccttgaaga agaacgcgca aatggtacgc caattgatga caaggctatc
    19021 caaggggtta aaatcggtat gatgggacct cttgctggta tcggtgaccc agtattctgg
    19081 tttacggttc gtcctatcct tggggcactt ggtgcttctt tggcttcaac aggtaacatc
    19141 gttggtccac ttctgttctt ctttggatgg aaccttatcc gtatggcctt cttatggtat
    19201 actcaagaat ttggttacaa agctggttct gaaattacta aagacatgtc aggcggtatc
    19261 ctccaagaca ttactaaagg tgcttcaatc cttggaatgt ttatccttgc agtgcttgtt
    19321 caacgttggg tatctatcaa ctttactatc gaccttcctg gaaaacaatt gtcagatggt
    19381 gcctatgtgg tattcccaga tggcgctgtt aaaggtgctg agttgaaaac tatccttgcc
    19441 aacgctattg gtggtatgag ccttgataaa gtccaagctc aaacccttca aggacaattg
    19501 gactctctta tcccaggttt agctggatta ctccttacat tcctttgcat gtggttattg
    19561 aagaaaaaag tttctccaat cgcaatcatc atcggcttgt ttgcatttgg tatccttgct
    19621 caccttgcag gtattatgta atcaaccaat ggaagtctga gatgaactca ggcttctttt
    19681 ttatgcttta tgtcaggaaa atcccactta aaatatggta taataactac aactacgcaa
    19741 tgaaaggaac ttaaatggct caatctttaa acactagtgt cgaatataag acaaaagctg
    19801 tctcctacct tggaatggga ggcaaagttg gtcatatttt actcggtgac aaggcccttg
    19861 aattttacaa cgataaaaat gtgaatgatt atattcaaat tccttggaca actatcaatc
    19921 acatcggggc taatgtttca agaaaaaaag ttagccgcca ctttgaaatt tttacggacc
    19981 aaggcaagtt tttatttgct tctggagact ctggaaaaat cttaaaaatc actcgtcaac
    20041 atattggtaa tgagaaagtg attacattac caaccttgat gcaaaccttt attaacaaat
    20101 tttttcgaca ttaaaaaaat aatgcgcagt gccgatttat catttcaaga aagcaaagaa
    20161 tagtagctct aaattgctat ttagtggaaa agattccctc atttgagttt actttttctt
    20221 gttttttgtt ataatagtcc taacggataa gtaatacctt tttttcattc agagagtctg
    20281 tggatgctgt gaacagatag ggaaaatgat atgaaattct accgtgtcat caataaaata
    20341 gagattaagt gcacagattg tgaagctgga tggaaccgcg ccaaagcgct ccagcatctt
    20401 cataagctgt gctttttcta tcgtcagaga atcacaagat ccaactgtct tacttagcct
    20461 tgtttcactg acggctacta ataactatct taaaggagct tctgtatgct agatcttaaa
    20521 cgtatccgta ccgattttga cactgtcgct gccaaattaa aaaaccgcgg tgtttctgaa
    20581 gacaccctga cccatcttaa agaacttgat gaaaaacgtc gtgctctatt agtgcaatca
    20641 gaagaattaa aagcagagcg taatattgct tctgctgcca tcgctcaagc caaacgtcaa
    20701 aaagaagatg ccactcaaca aattgctgat atgcaaaaag tctctgcaga tatcaaaact
    20761 attgacaatc aactagtagc tatcgaccag caagttactg acatcatcac tgttttacct
    20821 aatactcctc acgattctgt ccctgttgga gctgacgaag aagacaatgt cgaaattcgc
    20881 cgttggggaa cgcctcgtga ctttgacttc gaagttaagg ctcattggga tctaggcgaa
    20941 gatcttgata ttttagactg ggaacgtgga gcaaaggtaa ctggtgctcg tttcttattc
    21001 tataaaaatc ttggtgctcg tttggagcgt gctctttata acttcatgct ggatgaacat
    21061 atcaaagaag gttatcaaga aatcatcaca ccttacatgg ttaaccacga ttccatgttt
    21121 ggtacaggac aatatccaaa attcaaagaa gacacctttg aattagcaga taccaacttt
    21181 gtcctgattc caactgctga agtgcctttg accaattatt accgtgggga aatcctagac
    21241 ggcaaagaat tgccaattta ctttactgca atgagcccat cttttcgttc tgaagcgggt
    21301 tctgcgggtc gtgacacacg tggccttatc cgcctacacc aattccacaa agttgaaatg
    21361 gttaaatttg ctaaaccaga agaatcttac caagaactag aaaaaatgac tgctaatgct
    21421 gaaaatattc ttcaaaaact tggtttgcca tatcgcgtca tttccctttg tactggagac
    21481 atgggcttct cagctgctaa aacctatgac cttgaagtct ggattcctgc acaaaacacc
    21541 taccgtgaaa tttcatcatg ttcaaataca gaagatttcc aagcacgtcg tgctcaaatc
    21601 cgttaccgcg atgaggctga cggtaaggtc aaactccttc acacccttaa tgggtcagga
    21661 cttgctgtcg gtcgtaccgt agcagccatt ttagaaaact accaaaatga agatggttct
    21721 gttaccatcc ctgaagtact ccgcccttac atgggtggcg aaaccgtcat ttcacctaaa
    21781 taataaactc accccagaga tcattaaagt gatttctggg gtttactatt ttaaagagcc
    21841 accacatcac ttgaaactca ctacattgcc cctttaacaa cacttttctt cacactagtt
    21901 tatcaaaagt cttattagta tacccatttc cttatttaca agactagtta aaaacccttt
    21961 tggaaaggcc tcccttagct tgataaacac gtagggagac tccaaaagga tgttgttaat
    22021 atttacgaaa gcgttggtag cgctcatcta ataattggtc taatggctta gcttgcaaac
    22081 tggttatttg ttcgatgagg ttagctttga tgatgtcaac gatttcactt gaaaaataac
    22141 catgttctgg gataatacga tctactatgc ccatttgata caattcgcct gcggtaattt
    22201 tcatcaattc agcagcctct gtcgctcttg aaccatcttt ccataaaata gaagcaaaac
    22261 cttctggact aaggactgca tacatggtat tttcaagcat ccagacctga tcggcaaccg
    22321 ctaaggctaa tgcaccacca gagcctcctt caccaataat gatagcgata atgggaacct
    22381 tgagatcact catttccatc aaatttttag caatggcctc accctgtcct cgttcttccg
    22441 caccgacacc tggataggct cctgcagtat tgataaaggt gacaacggga cgtccaaatt
    22501 tttctgcctg tttcataagg cgcaaagctt tacgataacc ttctggattg ggctggccaa
    22561 aattccttgc caaattatcc tgtaaattct tacctttttg aataccaatg accgtaacag
    22621 gttgtcccgc caaataagct aaaccaccta caatggcacc atcatctgaa aaatggcgat
    22681 cgccatgcag ttccataaag tcatcgaaaa taaggttggc gtaatccaaa gttgttaaac
    22741 gcccttgatc acgcgcttct tttaaaactc ttgatacatc tgtcattggc cacctccatg
    22801 aaatgctact aagtgggcaa tcttgtctcg caactctgtt cgtttcacaa tagcatccac
    22861 aaaaccatgg tcttgtaaaa attctgcttt ttggaaatca tctggcaagt tttcacgaac
    22921 tgtggtctca atgacacgac gacctgcaaa gccaaccaag gattgaggtt ctgccaaaat
    22981 aatatcccct tccatggcaa aactagctgt taccccacca gtagttggat ctgtcaaaat
    23041 agtgaggtaa aagaggcctg cattagaatg tcttttcaca gctgcagaga ccttggccat
    23101 ttgcatgagg ctcatgatac cctcttgcat acgggcgcct cctgaagccg taaaaatcac
    23161 caccggcaga ttttcttcaa tagccaattc aaacaatcgg gtaatttttt ccccaacaac
    23221 agttcccata ctagccataa taaagtgaga atccataata gcaagagcaa tttgttgtcc
    23281 tttaaccata gctttccctg tcaaaacagc ttcatgcaga cctgtcgttt ccttggcttt
    23341 ttgtaatttt tcctgataac ctggaaaacg taacggatcc ttggtttcaa tacttgtaaa
    23401 taattcctgg aaagagcctt catcaactgt taaggtcagc cgctcttggg cagaaatcct
    23461 aaaattgtaa gaacaggttg ggcaaatctt tgccaatccc aaatctttct tataaatcat
    23521 gtgcttacaa gctgggcatt tcgcaaagag ttcatctgga acttctggga cattatggct
    23581 gacagatcct ttgaggaaat tattgggagt aatacggatg tatttatctt ttttacgaaa
    23641 taaagccata ttttctccta atctttattg taatgtggca ggaacgtttc catcaagaaa
    23701 gaggtatcat aatctcctgc aatcactcgc ttatctgaaa tcaaatcgag ctggaagtct
    23761 gtattggtga taatgccttc aatttccaat tcaactaagg cacgttgcat tttcatcaaa
    23821 gcgtcaaatc gattgcttcc atgaacgatg attttagcaa tcatgctgtc ataataagga
    23881 ggaatggcat agccattgta aactgctgaa tcaactcgta gtcctacacc accacttggc
    23941 atatacaagt ctgtaatctt tcctggactc ggtgcaaagt taaaagcagt attttcagca
    24001 ttgatacgac attcaataga atgtcccgtg atagtgatgt cttcttgatt aatcgccaaa
    24061 ggctgacctg ctgcaatttt gatttgctct ttgacaatat ccactcctgt cacaaattcg
    24121 gtgacaggat gctcaacttg gatacgggta ttcatttcca tgaaatagaa tttctcgctg
    24181 tcttcgtcca acaaaaactc aatggttccc gcattttcat aggctacagc ttcagctgct
    24241 ctaaccgctg cttgccccat ttcgtgtctg agggtattgc caatagcaat ggatggactt
    24301 tcttccaaga ctttttgatt attccgttgc aaggagcaat cccgttctcc caagtgaatg
    24361 atgttaccgt aagcgtctcc taaaatttgc acctcaatat gtctagctgg ataaattact
    24421 ttttccaaat acatggcgcc atttccgaaa gctcccaaag cttcttgact ggcagcattg
    24481 aaagccgcct ccaaatctgc ttctgtctcc actttacgaa tccctttacc tccaccacct
    24541 gccgatgctt ttagcatgac aggataacca atcttattgg caatagctaa ggcttcttga
    24601 gcgttataaa cttcaccatc tgaccctgga ataacgggca ctcctgcctt aatcatttca
    24661 gaacgagcat tgattttatc acccatttta tccataaccg atgcggatgg accgataaat
    24721 ttaatattca tctcttcaca catggtcgca aactttgagt tttcacttaa aaagccaaac
    24781 cctgggtgaa tcgcttgcgc tcctgtcaca atagctgctg acaagacgga attcatatta
    24841 agataggatt ccttggaacg ggcaggacca atacagatag cctcgtccgc caatatcgtg
    24901 tgcagagctt ccttatccgc ttccgaataa actgcaactg tggaaatccc taattctcgt
    24961 gcagcacgaa tgatacgcac tgcaatttca ccacgattag caattaagat ttttttaaac
    25021 ataagggttt cttcctccgc agaacaatca ttctcattgc ccacaggcaa aggttaatgt
    25081 tccacttgct gctagcttgc catcaacttc tgccctggct tcaacgacag caatggtacc
    25141 gcgacgcttg ataaaggttg ctgtcatcac aagttgatca ccagggacga cttgtttttt
    25201 gaacttcact ttatccattc cagcgtaaaa gaccaacttg cctttatttt cttcttttga
    25261 caattctaag acaccagctg tttgagccaa agcttccata atcagaacac ctggcatcac
    25321 aggatagtga ggaaaatgcc cgttaaagaa aggttcatta atagtcacat ttttaatggc
    25381 aacgatatgg tcgtctgaca cttctaatac acgatcaacc aataacattg ggtagcgatg
    25441 aggcaaagcc gcttgaattt ctctaatatc catcatttga tccgcaccaa tccttgtcca
    25501 aattcaatga catcttcatt tgataccaaa atttctgtaa tcacaccatc acatggcgct
    25561 ggcacttcgt tcatcacctt catggcttcg ataatcacaa gggtttgtcc tttttttaca
    25621 gtatctccga ctgccacaaa tggtggcttg tcagggctag ctgcaagata ggctacaccg
    25681 actaaaggac tttcaacaat atcaccttct gctacaaaag attctgcttg tggttgctcc
    25741 tctacaggaa catccttaac tgatgctgga ctagacgctt ccgaagcagt tggattcgga
    25801 acaagttgta cctgtggtac aggcacagca tgttcttgat ttgatgtcga tgcattgagg
    25861 tgttgttcgt ttttactaaa gattagctca ccttcatttg ttttgaataa aaattcacgt
    25921 aggcttgagg tatcaaactg agccatcaaa tctttgattt cttgaatatt caacctactc
    25981 ctcccaacat ttgaaagcta atacagcatt atgaccacca aatccaaaag tatttgaaat
    26041 ggcatagttg atagctgttt cttttccttc tccaaagatg acatttgctt cgatatcctc
    26101 tgataaagct tgtgtcccag ccgtcatcgg aacatagtta tgacgcatag cctcgatagt
    26161 ggcaatagct tcaatagcgc ctgctgctcc aagaaggtga cccgtaaacg attttgttga
    26221 agacaccgga acatccttac caagaacggc tacaattgct tgactttctc ctttttcatt
    26281 agctggggtt gaagttccgt gcgcattgac ataattaata gcactggctt caataccagc
    26341 ttcttgtaag gctaagtgga tggctttacg agctcctaat ccctcaggat ttggagatgt
    26401 catatggtag gcatcgcagg tatttccata acccacaatt tctgctaaga ttgtcgcccc
    26461 gcgttcttgc gcatgttcta ggctttctaa aacaagcatt cctgatcctt ctcccatgat
    26521 aaaaccattg cggtctttat caaatggaat agagcttctg cttggatctt cagttgttga
    26581 gagagctgtt aaactttgga agccagcaat ggcaaacttg gttatggccg cctctgaccc
    26641 accaactatc atcacatctt gagtcccaaa tttaatggca cgaaaggcat ccccaatcgc
    26701 atcatttgaa gaagcgcagg cagtattaat tgatttacat actccttgag cttttaaaga
    26761 catggcgaca tttcctgcag ccatatttgg tagcgctttt ggcaacgtca ttggcttcac
    26821 acgttttggc cctttttcat gtaagcgaat cacttgctct tcaatctccg caattccacc
    26881 aatacctgaa gcaacaataa cgccaaatcg atcggaatca atcatctcaa tatttaaatc
    26941 agcatgatta atagcctctt tcgctgcgta aagagcataa agagaatatc tatcgaaacg
    27001 gttcaaatct tttttcacaa agtatttgtc aaatggaaaa tcctgaattt cagcagcatt
    27061 cttgactgca taatcagtcg tgtcaaattt agtaataggg ccaataccaa tttggccagc
    27121 tttcagattg ttccaaaacg tttcaggatc atgcccgatt ggagatgtta gaccataacc
    27181 tgttaccact actcttttaa atgtcatttc actacgtctc cttattgcat tgtcataccg
    27241 ccatcaatag cgataacttg tcccgtaata taatcttgtt ctaccaagaa gcttgctaag
    27301 tgagcaactt cttgagcttt tccaatacgt ttcattggga tttgacttaa gatttgctct
    27361 tgcatttttt caggaaggac acctgtcatg tcggactcga taaatcctgg agcaatagca
    27421 ttcacgcaaa tgttacgagc agcaacttca cgggcaacag acttggtaaa accaatcatt
    27481 cctgccttag aagcggcata gtttgcttgc ccaatattgc ctgttaaacc aaccacacta
    27541 gagacattaa taattgctcc ttggcgggcc ttgatcattg gttttaacac tgattgagtc
    27601 atgttaaaag caccggtcaa attgattttc aagacgcgct caaaatcctc ttccgtcatt
    27661 ttaagcatca atttatcatt agtaatgcca gcattgttaa ctaaaacatc aatcgaacct
    27721 aaactttcga tagcttcatt gaccatacgt ttagcttctg atgcttctga aacatcccca
    27781 gagatggtaa caactgtaac accgtagtca gtaaaactag caacaagctc ctcagagata
    27841 gcagagcgac catttaagac aatattagct cctaaactgg cgaattgatg agccattgct
    27901 aaaccgatac ctctcgttga gcctgtgata aatatatttt ttcctttaat ttccatgaat
    27961 gtcctctcta tctaaaaata aacgtaagct taccatgttt tcaacactag tacatagtaa
    28021 atttttatca attttcttca caaaacctgt caaaacctta cctggtccta cctcaatgaa
    28081 ttgtgttatg ccactttcta ctaaagtcgc aacactgtca taaaaacgaa caggctccat
    28141 gacttgacgg gctaatagtt ctgggatacg gtctttttcc ataatattag cttcggtatt
    28201 accaaccaaa ggaatcttga agtcactgaa gttgtatctt tccaactctt tagccaacaa
    28261 gcggctagct ggttctaaca aagcagtgtg gaaaggacct gacacgttta aagggattaa
    28321 acgcttaact cccctttcct ttaaaagttc aactgccacg ttcacagcat ctgtctgacc
    28381 accaattaca atttgactag gagtattata gtttgctgga gcaaccactc catgtttagc
    28441 agctatttga cagacttctt cgatgacttg cacgtctgta ttcataacgg caaccatctt
    28501 tccagatcct tgtggtgctg cttcctccat caagcgccct ctcttagcta ctaaggatag
    28561 ggtatcttca aaagagagtg cccctgatgc taccaaagct gagtactctc ctaaggaaag
    28621 accagctacc atatccggtt taacgtgatg taagcccaaa acacggtaaa tagcaattga
    28681 tgatgtcaaa atagctggtt gcgtatagct agtttgatta agttttaact cgtcactatc
    28741 aatcaaacgg cgcaaatcgt atcccaatac ttgactagct tgatcaaagg tttttcttac
    28801 aatagcaaag ttatcataaa aatcccttgc catccctaat ttttgggcac cttgaccggc
    28861 aaataaaaag gctgtctttg tcattatcat tatccttcat gtgtttatct acttttctat
    28921 tgaaacagat tgccagcgct gagcttcatt ttgaataaca cgagctgcac cataataaat
    28981 atcttttaaa atcgtttcac agctttcttc ttttctcaca agccctgcaa tttggccagc
    29041 cataacagat ccattgacta catcgccttc aataacagca tgtcgaagcg atcctgctcc
    29101 catttcttca atatcagtag ctgttttttg accaattaaa aatgcttttt ctgctttagc
    29161 gtaagctgag gtcaatttat ttttaataga acggacaggg tggcccacaa cctgcgcaga
    29221 aatcaccgta tcaatatctt ttgctgctaa gattttatct ttaaaatttt ggtgggcatt
    29281 ggattcttta gcaacaacaa agcgagttcc aatttgaaca gcctctgctc ctaacataaa
    29341 tgctgctgct gcaccatgac catcagctat accacctgcc gcaatgacag gaatcgaaac
    29401 cgcttcaaca acttgtctta ctaaagacat agtcgttaac ttgccaatat gtcctccagc
    29461 ttccataccc tcagcaatca ctgcatctac cccaagcttt tccatacgtt tggctagcgc
    29521 aacgcttggg acaacaggaa caacgattat acccgcctgg tgcagtcttt ccatatactt
    29581 tcctggattt cctgcgcctg ttgttactac tttaacacct tcttcaatga ccagatcaac
    29641 gatatcatca gcaaaaggag ataaaagcat gatattaacc ccaaaaggtc tatcagtaat
    29701 agctttaaca cggtcaatat tggctttaac aacttctttt ggagcatttc ccccaccgat
    29761 gatacctagc ccaccagcat tggacactgc tcctgctaaa tcaccatccg cgacccaggc
    29821 catacctcct tgaaaaatgg gataatcaat attaagtaat tctgtaatac gtgttttcat
    29881 aataactttc tataaaaaat aaggagaata atttgataat caaactatta tagtaagaag
    29941 aaagagcgag ctagatccta aaaagagtct aatcccaccc taatggtttg attaatactt
    30001 attgtttttt tagtgatgaa catgaacata acagcagtaa gcttttcata gacttctgat
    30061 gttacttgtc acttttatcc ttattttgac ttttcctcaa cgtaagcaac aaggtcacca
    30121 acagtattta atccttcttc tgtttcaatt tgaatatcaa aagcatcttc aatttctgaa
    30181 ataacttgga aaacatcaag tgaatctgca tctaaatcat caaatgtagt ttctagtgtt
    30241 acttcttctg tctccttacc aagttcttca acaataattt cttgtacttt ttcaaatact
    30301 gccatgttta tttctcctta aaaaatataa atttgttttt ataaatgtgc taagcacatg
    30361 aataactaga ttttaacaat tagacttccc catgtcaaac ctccaccaaa accggaaagt
    30421 aagatttttt gggtaccatc taacctaatc tgtccctttt gaacagcctc tgacaagagg
    30481 attgggatac tagcagcact agtattacca taacgcatca tgttttcaag gaatttttcc
    30541 cgaggaacat caatcttgcg tgctatttta tcaagtatac gacgattagc ttgatgcaat
    30601 aaacaatagt ctatatcatc ttttgtaata tctgattgcg ccattagtgt gaggatgctt
    30661 tttgacacat ccctaatcgc aaaatcaaat atggcacgtc catccatctg aatagtcgct
    30721 atggcttttt tgccaattga gtaaggagat gaaagactag tttctcctga aattaaactc
    30781 tgacatctcg caccatctgt gtgtaatgtt tccgctaaaa catgtttatc tttactggct
    30841 tccagtagca cgccaccagc tccgtctcca aaaagaacgg ctgtcgctcg atcctgccaa
    30901 tttactaact tagataaagt ctctgcacct attaccattc cgttttggta ggcacctgat
    30961 gcaataagct tatctgccat agccaaggca aagacaaagc cactacaagc agcagtcata
    31021 tcaaaagcaa aagcacttgt agccgcaata gctgcttgaa ctttcgcagc tgttgatggc
    31081 atagtggcat cagggctgat agttgcaaca ataataaaat caatagcatc agcttttaac
    31141 ccagactgag tcaaaagctg atcagcaacc tgaatagcta ggtcactagt catttcatct
    31201 ctagaaatat ggcgttctgc tattcctgtt cgagaaaaga tccactcatg actagtgtcc
    31261 attatgctag ctaaatcatt attagtcact aactgctgtg gaacatagtg ggctacctga
    31321 ctgattttag aaaaaatcat ttaaaccaaa tcctccaaaa attgatgtag attccctagt
    31381 ccacgcacca atgcctgcat ctcttcatca ctcatatcag caatgacatg tccaaccata
    31441 tttttatgga actttgcatg gaggcggtcc aaaagtcgac ccctttttgt taatgacagg
    31501 taaacaactc gcctatctga gcgtgatcgc gttcttgcga tataaccttt tgcttctaat
    31561 ttatttaagc tagtcgttac tgtccctaac gttaccatta attctctggc gatatcactt
    31621 ggagtcacct gatcatattt gccgataatt tcaatagtgt gcatctcttt taaagagaca
    31681 tcactaaact gactcgtctt taagctcatt tcttcaataa ccaaaatccg gttgaaaata
    31741 tcaactaagt attggttaat tttgtcatat tccaagtaaa cacctcctag caataaactt
    31801 tgacaatcaa attatatcaa agatcaaagt attttgcaag caatagctgt cttacttacc
    31861 ttgaaaattt ggtcggcgcc tttctccaaa agctatgaca ccttctttaa aatcttcctt
    31921 gaaagctagc tcctcttgaa tagcaagctc tgccttagca taatcttccc atcctgtgaa
    31981 aaagctttgc cagaccaatg atttcattcc agcataagaa tttgaagagc cacgtctcaa
    32041 tcgctttaaa agttgaagac aaactttgtc tagtttatca gattctgccg tacggtagac
    32101 aaacccataa tcgagacctt tatcagcagt aattccttca cctgtcatca caaggtgagt
    32161 tgcacgatta agtcctactg cacgagtcaa tagaaataaa ccaccggcat ccggtgctag
    32221 tccaacattt acaaaagctt ggataaattt tgtttgagta ctagcgatac aaaaatcaac
    32281 agctaaagct atattaaaag ccgctccagc tacagctcca tcggcgcaaa ggatgactgg
    32341 ttttggcaaa tgcttgattg caaaagaaat ttcttgtacc agttcagcaa tcttgactag
    32401 cgactgcaca ttatcttttg caacagcttc ttgcatttca actaggtcac caccaactga
    32461 aaacactttt ccaacggctt taattaataa aaaacgcaca gatgtatcgc gtttaacttc
    32521 tgctaatgct accagaatct cttgacaaat tggaatatta aaaccgtttg aaacctctgg
    32581 acggtttaaa gtcaatgtcg caagatcatc tacaacatca aagatgatgt gtttaaactg
    32641 cataacaatc ctcttttctg ataatttatt tgactaagaa attatttctc tttaaaatca
    32701 tttgataatc aaatcaatta cctaattatg atatactaaa taaaccattt tgacaagaga
    32761 aaaaaacgat atctataaaa gaaaacgttt tctctaactg ttttgacgta aaaaaacgta
    32821 taacttcggg aaaattatcc tgaaattata cgtttgacat ctttaaatat cctctaaggc
    32881 atctttcact ttatcaaaaa aacctttttt ctttggatgt aacatttttt caccactcgc
    32941 ttctgcaaat gcttgcaagg cttctctttg agcgtcattg agtttggttg gggtcacaat
    33001 attaacagta acatgttgat ccccttgacc tccaccacgg agttttggtg ctcctttgcc
    33061 tttgaggcgg aaggttttac ctgtttgtgt cccagcaggg atagccatct caacatcgcc
    33121 atgaaccgtt ggaatttcaa cagtatctcc taaggctgct tgagtaaaag aaatatctaa
    33181 gttgtagtaa atagtggaac cattgcgttc aaattgctta cttggtaaga cattcaaaat
    33241 aacaaataaa tcaccataag gtccgccatt aaagccagct tctccttgac cttgtaaacg
    33301 gatttgctga ccagtctcta caccagctgg aatcttaaca gacactttat gagcttgctt
    33361 ttcatgacca gtaccgtgac aggtttgaca gggttcttta atttccttac cactaccatg
    33421 acaaatatcg caggtgactt gtcgacgcat cataccaagt ggtgtttggg tgtcaattgt
    33481 cattacacct gaaccatggc acttacgaca agttactgga gcggtaccag gttttgcacc
    33541 tgagcctaaa caagtgccgc aggttgcttc gcgattatag ctaacttctt tttcaacacc
    33601 aaatacagcc tcttcaaaag ataaattaac acgatattgc aaatcgtcac cttgacgagg
    33661 ggcatttggg tttcggcttc caccgccacc aaagaagctt gagaagatat cttcaaaacc
    33721 accaaagcca cctccgtcaa aaccaccaaa gccgcccgct ccgccaccaa agccgccttg
    33781 agcacctgca gcgccgtatt gatcataagc agcacgcttt tgtgaatcac ttaaggtttc
    33841 gtaagcttct tgaacatcct tatacttttg ctccgctcca gcttctttat tgatatctgg
    33901 atgatatttc ttagacattt ttcgataagc ttttttgata tcgtcctgag aagcgtcctt
    33961 agaaaccccc agacgatcgt aatattctgt attgttcata atgtaagata ccaagccgta
    34021 aaacgactca atgaaaaata ggaaatccga caaagatact ctcgtatcta ggaggtattt
    34081 ctcttttttc gcagagtcgt aggcgtgttc gaatccgcaa aagagtcttt acacgcttta
    34141 gcctgtgttc gaataatcga acttgtattc ctttcttaaa atattttgac gtcagcattt
    34201 ttacatttta tttagccaaa aacagaggtt tggtacaacc tctgaattcg gatattaatg
    34261 ttactagata actaaatcat tacttttctg taaattcgcc atctacaaca tcatcattat
    34321 ttgctgaatc attagcttgt gcaccttctg caccttgtgc tgcttgtgct gcttgttgag
    34381 ctgctgcagc ttgctcgtac attttaacag ccaaagcttg cgctttttca tttaatgctt
    34441 caagtttagc tttcatgtcg tcaaggttgc cagattcttg cgcagctttt aactcgtcaa
    34501 gagctgattg cgctgcatcg cgttctgtat caaagccttt accttcagtt tctttgattg
    34561 ttttttcagt agcaaagata gcttggtcaa cttcgttttt aaggtcaact tcttctttac
    34621 gtttcgcatc ggcttcggca ttagcttcag cgtctttcat catgcgatca atttcttctt
    34681 cagaaagtcc gtcgtttgat ttgataacga tgtgttgttc cttttgcgta ccaaggtctt
    34741 tagcttttac agaaacaata ccgtttttat cgatatcaaa tgttacttca atttgtggga
    34801 ttccacgagg tgcagccggg atatcagtca attggaagcg accaagagtc ttgttatctg
    34861 ctgccattgg gcgttcacct tgaagaacat ggatatcaac agctggttgg ttgtctgctg
    34921 ctgttgagaa gacttgtgat ttagatgttg ggatagtggt gttgcggtcg atcaatttag
    34981 tgaagacacc acccattgtt tcaataccaa gtgacaatgg tgttacgtca agaaggacaa
    35041 cgtctttcac atccccagtg ataacaccac cttggatagc agcacccata gcaaccactt
    35101 catcagggtt tacagattta tttggttctt taccagtttc agcttttaca gcttcgacaa
    35161 ctgctgggat acgagttgat ccaccaacaa ggataacttc atcaatttct gacaatgaca
    35221 atcctgcatc tgaaagggct tgacgaactg gagttttcgt acgttcaaca aggtcacgag
    35281 tgagatcgtc aaatttagca cgagataagc tcatctccaa gtgaagagga ccagcagaac
    35341 cagcagtgat aaacggtaag ctaatttgtg tttgtgtcac acctgaaaga tcttttttag
    35401 ctttttcagc tgcatctttc aagcgttgaa gtgccatctt atcttgtgat aagtcaatac
    35461 cattttcttt cttaaattca gccactaaga aatcaataat tttttggtca aagtcgtcac
    35521 caccaagttt gttatcacct gctgttgcaa gaacgtcgaa gacaccatca cctaattcaa
    35581 ggattgatac gtcaaatgta ccaccaccaa ggtcaaaaac taagattttt tcatccttgt
    35641 cagtcttgtc cataccataa gcaagtgcgg ctgctgttgg ttcgttaacg atacgttcta
    35701 cttcaagacc tgcaatttta ccagcgtctt tagttgcctg acgttgtgca tcgttgaagt
    35761 aagctggaac agtaataact gctttttcta ctttttctcc aagatagtct tcagcataac
    35821 ctttaaggta ttgaagaatc attgctgaaa tttcttgagg agtatattct ttaccatttg
    35881 cagaaacttt ttcagaagtt cccatctttg atttgataga gattattgtt tctgggtttg
    35941 tcactgcttg acgttttgca gcatcaccca cgataatttc accatttttg aatgatacta
    36001 ctgaaggagt tgtacgattg ccttctgggt tagcaatgat ttttgattca gtcccttcaa
    36061 gaactgctac tgctgagttt gttgtaccta agtcaatacc aataatttta gacatgttaa
    36121 tacctcttat tttataatac tttattactt tttatttcaa tttatcttag taagcactcg
    36181 aattatttta cttccaattc taagcaatca ctatagttta atcagcaagc gaaatagctt
    36241 ctaacttgct atctagttta ctgtcattac ggacaaaaac gaaaactcat ttaccttagt
    36301 tataaacaac taccatcgct ggtcttagca gacgctcgtg caatttatat cccttttgaa
    36361 agacttctgc aatgctatcg gctggatgtt catcatcggc tgggagggtc tgaactgcca
    36421 tatgaaagtt gtggtcaaac gagtcgactt ctacttcttc tacgccttct tcctttagtg
    36481 cttgaataag gctatcacga gtcatttcta aacctttttt aacatcatct gtcaaccctt
    36541 caacagccaa ggcacgttct agattgtcaa gcgatggtaa gattgctttt gccagatcct
    36601 gagaacgata gcgttgaagt tgttgacgct cttcactaga gcgacgctgt atattctgca
    36661 tttctgcatg agctcgcaag tatttatttt caaactcatc agcacgttcg tttgcaagtt
    36721 ctaactctga tttttcagga gtttcttcaa taacttcctc aactgtctct tcagtttcag
    36781 tggcttccac ttcttcttgt aaatcgtctt ttttaatttc ttctgacact gagtgcctcc
    36841 ttttaaataa cttattgaat actgccatta tcagtgaact tcataatggt tagaatttag
    36901 gtatcgataa taatcaccta atttagcagc caataccttt ccaataatgt ttaccaaact
    36961 aacagaccta cgataatcca tatcaatagg accaatcaaa ctcaggagtc caaacccacg
    37021 gtaaggaatc aaaaatttgt gagttaaaac tgacacatct gcaagtgcgg cttcttgact
    37081 atctgccact tggacagaag ccatctcacc ttctttcaga ctttgcctca aagaaattgc
    37141 tacttgctgt tcattatcca aaaactgata cgttgataga tctgaatacg ttaaagaatt
    37201 taccttgcca gcaacaaata ccgtttccaa aaacagctct gaaaaaacat aatcaaatag
    37261 ttgtaaaaca ttatccgtag tcacaaaata cttttgaacg atctgaggaa tttctgtcct
    37321 caacttataa tgaatatcta tgacactatt atccagcaag cgctcctcta cgatagcttt
    37381 aaatgctatc aagtcacgtg tcaaaaagtt tcttggaata gcaaactgca ctgtcactgg
    37441 cttagattca tctaaagtca tgactgctag agcatcatgg ttgctaagct gaacaacatc
    37501 aaaccctgtt aaacgttgac gagctggctc cacatctaaa ataacggatg tatagcccgt
    37561 catctccgct aaaatgtgac tagctttttg aagcatgtct tctaatttga atgcttcaaa
    37621 atcaaaagct tttatgacat gataaatatc ttgctcatca atactatcta gcctgaggga
    37681 gtgctctaca aaatacttaa aaccagctgg acttggcatc cgtccactag aagtgtgcgc
    37741 tttttccaac aatcccaact tctctagttt tgccatatca ttacgaatag tggcgctact
    37801 agaatcaatc gttctctgta aagctttaga ccctactggt tcatgagttt gtgtaaatag
    37861 ctcaacgatt aaattcaaaa tatcattttg acgttgtgta atcacaaacc aaccactccc
    37921 tttcgtttag cactctattt agtagactgc taatttataa ttctattata ctctttatgg
    37981 gagacatgtc aagaaaaaaa ctcaaaaaaa ttagcactct tttataaaga gtgctaattt
    38041 cagtcatagt ttgttaaatc gttactttca atgacctgaa ttagtcgcct agcataggtt
    38101 ttatcagtat aatgcaaata cttttgtaaa cttttagctg gtgctttata ccctttttct
    38161 gtagcaagat tacgatacaa acgcttatcg acttctttgc cctgccgaag cattcgtaaa
    38221 taatctctaa ttgcactagc atcatcttta taaatagcat atctcacgtt ttggttggtt
    38281 tgtttagggg actttagggt aatggctgct tgtcctggag ttgctttctt gctaaaaaga
    38341 ttatgatact tagacgctag taatgttttt ccatcatggg tttccaaaag aatttgagca
    38401 atcaaaatag atggtctaat gccataatat tttgccaatg gtttaacttc tttacccatt
    38461 tttgtaataa attgtttttg gctgtagttc acccttactt ctttatctgc actagctatc
    38521 ctttggctac tcagtaaggg acaaacaatc agcaataaaa agcaagctag aagcgttaaa
    38581 aaatacggaa actttagtcg ttttctcatc gtttctcctt taaagcagca atgtactctt
    38641 ccaacgttag gttgtgctga gccatataac gagcagacgc cttgcctaca tagcggtaat
    38701 gccaatcctc ataatcaacc cctgtactag tcttttttcc ttctggaaag cgcaagacaa
    38761 acccataatc aggtgcaatt ttttgaactg ctttagatac cgatgggtca ctggcattta
    38821 aagtatctac ggtgcttatg tcaatagcaa gaccagtgtg atgttcacta gcccctggcg
    38881 gctgtaaata ggtttgcacc aaagcctccg cagattcttg tgtcaatgtt ggatcgttag
    38941 ccatctcttt tttaatataa gattggtaaa gctctgcttg gtaagctacg gagcgatagc
    39001 ctgaaataag gtgctcttgt gggtcaatag cttgtgctgc tgctaaaaag tcactagtgg
    39061 cttgctcaat gcgtttatcc acagaaatac cattaatgtc agctaattca ggactcattt
    39121 cttttgtaat gtgatcgcgg tttactaaaa ccaactccca atcttcaaca gataccttag
    39181 gtaaagctcg taaacggtcc gtttttttga tatctttttg ttggatttct tttttattca
    39241 actgagttgg tgttactgac tcttctggtt ttataaagag gtaaagccct cctaaaaaaa
    39301 caataacaat tagcaattgc actaaatagt ttaacgaatt atatttcatc tgaccgttct
    39361 tctattattt cacgaccgcg gtagcggtaa ctcatatctc caatagtctt tatcgtaaat
    39421 tggccatcat caaattcaac aactgtaacg ctcccattat caatatactg tttgtctcga
    39481 tctggatcaa tcaaccacag aaacgttcca attgtcatac catggctaac cacaagagca
    39541 tttccgccgc cagcattttg aatggacaag gcaatagctt caaacccctc ccaaatgcgc
    39601 ttacgaagaa cttcccatgg ttctgcccaa ttagcggtat ctatttccac gatgctttct
    39661 gccagttcag aatagggaac atcacgtagg ttatcacgat tttcaaaggc ttttgttctt
    39721 ggaaggacac ctagaaataa ttctgaatca taagtccctt ctagactccc aaaacaccac
    39781 tcacgaatac gattatcttt agtataaggc aaaaattcgt tttctgattc tcttaaaata
    39841 atttctattg tctgcatggt tcgacctgaa tcacttgaaa acgcagcctt aaatggtata
    39901 gttgcatctt ttaaacctaa gccaagttct cgaatacctt cttctccttt ttttgtaaga
    39961 ggtgtgtcac tccaaccctg agcgcgacca atggtattaa acatcgtttt tccatgtctg
    40021 gcaatataca accttgtttt tgtcatttca acctcctaaa ctgtcttatt aattattata
    40081 gcatttaaag aaaacacttg caaaacactt cctgatggct atttgagatc aaatagacca
    40141 ctgacttatt gtctatttta ttaaaaataa tgctattgct acaattcaaa tcatcacata
    40201 aatttccaaa cgattacatt tgtgtgtttc gctcaaatgt atataacaac agacccacac
    40261 tacaactaaa ctgacgttac aaaatgatgt caaaacagta acaaaatcta actatttgtc
    40321 aagaaaacga tattaaattt tcacacaact atcttataat gaggatgcaa ccaataaaaa
    40381 gataagacat tttatgttgc aaaaaaggct gcttggaaac ttccatgcag ccttttttta
    40441 ataccttttt ccaaaaatag ctgaaacaag tacaattaca attgctgctc ccaaaatgga
    40501 cgggaaaata gccatacctg ccaactgaat tccccaatcc ccaaaaagcc tttgcccaac
    40561 agctgaccct atgagacctg cgataatatt agtaaaacaa cccatggact ggcttttttc
    40621 agtcatttta cctgctatca tgccgataaa ggcacctaca attaaagacc atatcatcat
    40681 taacacctcc tttcttgtaa aatcctttta gaagaactgc tatccattaa atgttcttaa
    40741 ctttagttga ttcctttacc ttcttcttta gtaagtgttt ccgtgcctga gtaaaataga
    40801 aaaaacaatt ccttctatta agatagatcg agaacgacta gaagtcttcg cacactaaat
    40861 aacttaacaa actttatcac acagctaatc gctaataata gtgtagacaa acgtgatggt
    40921 tcattaaata cccgtcagaa actcctgaag gttctaaagc aatacctgtc agtcttattt
    40981 tagcatagat gatggtcttt ttataggcgg tcactaacat gacatacaaa aaggcagcct
    41041 gtgaaagacc gaccgccttt ttttcagaga caaaatactt taacttattg ctatcagcaa
    41101 ctatcaatct agcaattttt gcaattcttg tgccaataat tgttgagcga cttgtggatt
    41161 agcttgacct ttggttgcct tcatcaagaa gcctgtgaaa gccttatcag cattacgttt
    41221 gcctgatttg aaatcagcca ctgcagcttc attatcagca aagacttggt gaataattgg
    41281 taccaaaaca gcgggatcag aaatctgaac aagccctgcc ttttcgacgt aggcgcgagc
    41341 tgagccaccg tttttagcca aatgcacaaa gaccttctta gccattttag aagagattgt
    41401 accatcagca atgatagcaa tcatctccac caaattttct ggtgtcagag cgatttcttc
    41461 aatggttttg ccttctgcat ttaagaattg ggcaacttcc ccttgcaacc agttagagac
    41521 ttgcttggcg tcgccaccaa gacttactgc agtttcaaag aaatctgaca aggctttggt
    41581 agctgttagt tggctagcat cataagttga gagaccaagt tcctcttcgt atttagcacg
    41641 acgttgagct gggaattgag gtaattgagc acgcatctca tcaatccaag catcatcaat
    41701 ttcatataag ggtaggtctg gttctgggaa ataacgatag tccgctgccc cttctttgac
    41761 ccgcatcaaa atagtcccct tattcgcttc gtcatagcgg cgtgtttctt ggcgtatcac
    41821 accacctgaa cgcaagagtt tggcttgacg ttccacctca aattcaagcc ctttacggac
    41881 atttgagaag gagttcaagt ttttcaattc ggtctttgtt ccaaattgtt cttgcccgta
    41941 aggacgaaga gaaatattgg catccacacg catggagcct tcttccatct tgacatcaga
    42001 aatacccgta tactggatga tttctttcag agctgtcaaa taagcatagg cttcttcagg
    42061 agaacgcatg tcggcttctg acacgatttc aatcaaagga actccttggc ggttaaggtc
    42121 cacataagaa taaccatctg tgccatgagt gtttttacca gcatcttctt ccaagtgtgc
    42181 gcgttcaata cgaattttct tggttgagcc gtcttccaat ttaatctcaa tccatccgtt
    42241 gtagccaatc ggctcgtcaa actgtgaaat ttgataagct ttaggattat ctgggtagaa
    42301 ataatttttg cggtcgaaat gcatctcttt atggatgtcc atattgaggg caagcgcagc
    42361 ttttatgccc gcatcaataa cgcctttgtt catgactggt aagacccctg ggaaagacca
    42421 atcaatcaca ttcgtgttgg catttgggtc ttcaccaaag tgagctgacg aaggtgagaa
    42481 aattttggaa ttggtattta attccacatg gacttcaagc ccaataatgg tttcaaaatt
    42541 cattacttgt cacctccaaa aataatcggt tgttgcttgt gataatctgt caccgcttca
    42601 aaggctgctg ctgcctgata gatggtttct tcagcgtatt tcggaccaat taattgaagc
    42661 cctactggca agccatcgac gaatcctgcc ggaatagaaa tacctggcag accagctaag
    42721 ttaaccggaa tggtcaataa gtcggccaaa tacatggcaa caggatcatg gttgagtgtg
    42781 tctaagccaa aagcaaccgt cggtgttgtt gggcctaaaa taagatcata atccgcaaag
    42841 accttgtcaa aatcttgaat aatcaaagtg cgcacttgac cggccttttt gaaataagcg
    42901 tcataataac ccgatgacaa actaaaggtt ccaagcatga tacgacgttt cacctcatca
    42961 ccaaagcctt ggctacgagt gttaacatag atttcatcca agtttttagc atcgtcagca
    43021 cggaaaccat agcgaatgcc atcaaaacgt tgtaagtttg aagacgcttc tgacgaagca
    43081 ataatgtaat agacagccac accatatttg ctatgtggaa gactaacttc ctcaacagta
    43141 gctcctaagg cttcaaattg tttagctgcc gcaagaaccg tttccttaat ctcaggatca
    43201 atcccttcgc caagatactc tttaggaagg gcaatcttca tgcctttaat gtcacgacca
    43261 atcttagatg tgtagtctgc aatgcggaca ggcgctgaag tggcatcctt gacatcgcta
    43321 cttgcaatca catttaataa ttgggcgttt tctttgactg tcggagcaaa aggtccaatc
    43381 tgatcaagtg aacttccaaa agcaatgaga ccatagcgag aaacagtgcc ataggttggt
    43441 ttcaaaccga caacaccatt aaatgcagct ggctgccgaa tagaaccacc agtgtctgaa
    43501 ccaagagata aacggacttg tcctgaagcg actgctgtgg ccgaaccacc tgatgagcca
    43561 ccaggtactt ttgtgtggtc ccaagcattt ttcgttttct tgaaataaga ggtttctgtt
    43621 gaaccaccca tggcaaattc gtccatgttg gtttttccaa taacaatcat gtctttagcg
    43681 taggcatttg ctactgatgt ggcattaaaa atcggctcgt agttatacaa catttttgaa
    43741 gcggctgtgg ttaggatttc cttggttgaa atattatcct taacagctaa cggaatacct
    43801 gacatgaggt tatcagcatc aatacctttg gcatcaattg ccgcagcttg tttaagagca
    43861 acttcttctg aaacagtgat aaacgatccg acagcctcct cacgagactt gatgtcttca
    43921 agtgttgctt gggtcaattc tgttgctgaa atctccttag ctacaaggag gtcatgcaac
    43981 tcttcaatgg ttttatgatt aaaagacatt aggcatctcc tccgtcatcc aaaatagcag
    44041 gtaccttgat aaagtgattt tctttttcag gaacattttt aaagagcaag gcacggtctg
    44101 ttccttcttc agcgacatct tgacgcatca catttttctt atctgccatg gttgttgtaa
    44161 tggcgacacc ttcggtatca acttcgttca gcaattcaac catatcaacg attttggata
    44221 aggtcgttgc aaaggttgtt gtctcacttt ctgaaaatga taattttgat agcttcgcga
    44281 catggcgaac ttcttcttca gaaattttca tgatttctcc catccaagat gatcagaagt
    44341 attccaattc caaagaacag ccctgctatt ctccaaaggt agcggaaaaa ctcctcacat
    44401 catttttaca tagtctcaat tattatatca caattgctcc catttaccat aggtgactaa
    44461 tgcaattcta gaaagccata cagcaaaaaa cttcctgact aaggtcagaa aaccttagtc
    44521 aggaagtgtg acaaactaaa ctctatttgt cttgggtaag actgtggcct gaagctttga
    44581 tggcagcctg agcagccgcc aagcgagtaa gcggcactct aaatggcgaa caagaaacgt
    44641 aggtcaggcc ttggctgtgg caaaaggcaa tggaagcagg atcgccacca tgttccccac
    44701 aaataccaag tttcaactca ggcttaaccg aacgggctaa agagacggcc aatccctttc
    44761 tgatcaaagg tctggaacgg ctccttatca aaaatacccc tgtcaacgta ttcttccaag
    44821 tattttccta caaacatcac agaaaaagta acgttctttc aagtcggtaa tatgtttacg
    44881 aaggtagtaa aggggtgctt tattctaatt taccaaatcc tcaacgattg taacaacatg
    44941 tgatgtgata agcctaagat aaaaatggta cagactctag cattcaagag tttgaagctt
    45001 tatttatatt ctaatgctga aaagactaga gtttgtctaa tggctgtgag acgatcctct
    45061 aaaccatcaa ctcaaatcat ttctcaaaca gctaaaatcc tgtctccttc aaaaaaacat
    45121 gtgttctatc tgacacagtc caaagtttag ttgcctttta gacagcacaa gaatcatcag
    45181 gactaattct gaccagcatg tcacatacct catctaccta acccatacat acggtaaaac
    45241 cacatagagc aatgattacg gttaccaaac tcttagtcac tgaatcaata gtttggtagg
    45301 ctcttttagt aatcgttaat aagcttagca ccaagaacct gctcaaagtg agccaaagac
    45361 cactcataag attcttttgt aaggctagcg acagccgatt taacaatctc taattgataa
    45421 ccaagatgat aagcgtcaat agcagtatgt aagacacaga tatcagataa aactcctgtt
    45481 aacactaatt gagtgatacc tctttctcgt agtcgaatat ctaaatcagt ccccgaaaaa
    45541 gctgaataat aacgcttatc aatccaaaaa actctgggat gttgcttcat atgactgtaa
    45601 acttcagcta gtggaccata aagatggcgt ccagtagttc ctttgatatt atgtgctgca
    45661 aatagcttac tctcaggatg ccaaggatca ttttgatcat gacaatcaat agcaaaaaaa
    45721 atatagtctc cttgatcaaa tgccgtttta gttacctctg ctattttagt ggcaatagcc
    45781 tgagcagatt tacctgcact taatttacca tcatctgcta caaaatcatt tgtgtaatca
    45841 attgaaatca atgctctcat cactatctcc taaacaggga aacctctccc cttatctctt
    45901 atatatggca ttgtatcagt ttttattaca ggtatcaaga catctatttg catctaccat
    45961 taacagcaaa aaacatctct tttcaagaga tgttgtcttt ttctatttaa aattctttta
    46021 atttagcaaa aataccttcg ttgataactt tgaggtatgt ccctttcata ccaagagaac
    46081 gactttcaat aatccctgca ctttctagtt tacgcagagc attgacaata acagaacggg
    46141 taataccaat acgatcagca ataacagaag ctgttaatcg tccttcatta ccatctaact
    46201 ctccaagaat tgctgcaaca gctttcattt ctgaataaga aagcgtatta attgccatgt
    46261 tgaccgctgt ttgtttacgg atggtgtctt ctaagttttc tgtctgaaga tttaataatt
    46321 gaatccccac aacagtactt gagatctcaa ccaaaatcaa atcatcatca ctaaactcat
    46381 tgtcattacg ccagataatg agtgatccaa ggcgcatccc tccaccataa atcggcgcaa
    46441 tagtcgttag acctcctgga taagtgtctt tagactcaac agggaatata gtcaattcat
    46501 tttcgacaga aaggttagct tctgtatcgt aaactcggct agcagccttt acataagtat
    46561 ctggaaattg tttagcttca aaaaattcct caacacgatc agtgttagtt ttatatttca
    46621 tggcataacc aagcagtgtg ccgccgccat tgataataca agcattgcag tcaatgatat
    46681 ctgctaggcg agatgccatt gtgttatacg gtaattctgt ttctaggcta tctacggaac
    46741 gctgcaaaat agatgtgatt ttacgagttt tttctaataa gttaggcatt tttttccttt
    46801 tcctttgaat tatttgcgct ttcattataa caaagctaac tcgcttttgc aaggaattat
    46861 cagaaaattt tctattctta ctacaattcc aactattgat gccttattat cacttcattt
    46921 aaaggagata agcactagct tgttagagca tagggtcaca ttcttttaag aaacgctatt
    46981 tttattaatc aaagatgagc attgcattaa cgtctatact ggtataagac acgtgtaatc
    47041 ttttcttgga catcttctaa ttcttctaca cttggtaggt aaacaatacg gaagtgatct
    47101 ggatctttcc agttaaaacc acgtccatgt accaacatca ctttttcttg ctttaataac
    47161 tgtaagacaa attcttcatc atcatcaata cgatacatct gacgatcaat tttcggaaat
    47221 aaataaagac ctgcttcagg tttaactgcc gataagccag ggatagcatt aatagcttca
    47281 taaataaaat tacgttgctc aaaaatacgc cctcctggca gtaacagtgc atcaactgat
    47341 tgatggcctc ctaaggaagt ttgaacaact tgttgggcta aaacattgga gcataaccgc
    47401 atattggcaa gcatgttcaa cccttcaatg taacctttaa catggtcttt aggacctgat
    47461 aagaccatcc atccaacacg aaaaccagca atacgatgag atttggaaag gccattcata
    47521 gatacacaaa aaacatcagg tgccaaactt gcaatagcaa tatgctcttt accatccatc
    47581 accaaacgat catagatttc atcggcaaaa ataatcagct ggtgttctct tgccaaagca
    47641 acgatgtctt ctaaaatctc cttaggataa agggctcctg ttgggttatt aggattgatg
    47701 accacaatag ctttggtgcg actcgtgatt tttgatttga tatcagcaat atcaggatac
    47761 caaccagctt cttcatcaca aagataatgg accgcttttc ctccaccaag actcacacaa
    47821 gccgtccata aaggataatc cggcattggt actaaaactt catcgccatt atctagcaaa
    47881 gcttgaaggg acatggatat caactctgac acgccatttc ccaaataaat atcttcaatg
    47941 tcaacatctg ggaagccctt gagttggcaa tactgcatga tagccttacg cgctgaaaaa
    48001 atccctttac tgtcagaata gccctcactt agcctcgcgt tgacaattaa atcacgaatc
    48061 acttcatctg gtgcttcaaa accaaaagca gcaggattgc cagtatttaa acgcagaatt
    48121 ttttcaccac tcgcaatcat gcgattagct tcatccaaaa caggccctcg aatatcatag
    48181 gcaacatgtt ctaattttga tgatttttca ataattttca tagtctcata cacctcgtat
    48241 tccatattat aaaccaaaat acttaaaata gaaagaattt atccatcaaa gcttaggaca
    48301 gctaatcgtt ttaacacagg tcttatgaga cgataataca gtctttagtt tagcaaaaat
    48361 aatggatcgc tttcaaaatg actcaaaaaa gagtataatg aaaaaaagaa taaaagctat
    48421 tcttgtcaaa ctgttaaagg aggacagttc tatgtcacta aaatataaac gtatcctcgt
    48481 tgctattgat ggctcttatg agtctgaatt agctttcaat aaaggcgtta acgtagcact
    48541 acgtaacgac gctaccttac tactagtaca cgttattgat acccgtgcct tgcaaagcgt
    48601 agctactttt gatacttaca tctatgaaaa attagaacaa gaagctaagg atgttttaga
    48661 tgattttgaa aaacaagcac agatagcagg aattacaaac atcaaacaaa ttattgaatt
    48721 tggcaatccc aaaaacttac tagctcacga tattccagat cgtgagaacg ctgatttaat
    48781 tatggtagga gctactggtc ttaatacctt tgaacgcctc cttattggct catcttctga
    48841 gtacattatg cgacacgcta agattgactt acttgtagtc cgagatagca ctaaaacact
    48901 ctagtctatt acaattttca aacaccaaaa aacaagcagc atctacaacg aaattgcttg
    48961 ttttttgtgc tgagctaagg ctagtcaata tctttttatt tcttgatatt taaaagagta
    49021 aacctctatt tatcgaatcg ttgtagtgat ttttgtaatt gtttgtctaa ctcttttttt
    49081 atggctactt caggtgcgtg acgctcttgc caatagtcag gtttttgaat tttatgggta
    49141 acggggtcaa agtgtgcctt gccatctgga aaaattttag ccatatttgc ttcatgtact
    49201 gcttcaaata taggttgtgg atctactccc atcagtacaa aagaaccata agtaaaataa
    49261 agcaaatccg ctaaggcatc aacttgccca atcaggggcg tttcaacatg ttttttagct
    49321 tgtaccttat tagctgcttg gtcaacagca ccatgcaaat cgaaaatagc ctgtgtaaat
    49381 tgttgttggt ctcccttgct tgctgcgtaa agaaactcaa cgatttcttc tactttgaag
    49441 cctgacctat aaccagcttc tgaaatggta taactacgcg gtgtttcaat agtatctgag
    49501 tccatcagac gatgaaaatc tttgacttta ttaaaatttt catcacggct tttaaagctc
    49561 ttctctacat caaaatggat gagaccgtag tgagctaagg ctttggaaat cccatcatta
    49621 ttattagagt cggtagtgaa atgggctcca tcttttacca cagtttcagc atttcccata
    49681 gcaacaccga taccaactcc tgataacatt tcaaggtcat tatctgaatc tccaaaagcc
    49741 atcacttcag acaagtcaaa tccaaacatc tctcccaaac gttcaattcc ttttattttt
    49801 gattgatcaa cagagatcag atccaaggaa taaggactac ttcttgtaat ttttatatga
    49861 gggaacttct cttgtatttt cttagtttca gcttgtgacg ctaccagaac aacctgataa
    49921 ataggctccc gcataatagt tactaaattt ctaaaactct gtggcttgat tcggcgaatc
    49981 aaatgcttaa aactaccctc aactgttctt gcccaacttt tgggcacaaa actactaatg
    50041 acttgtccaa atgggctagt ccccatatca ataatacgcg atcctgctaa tccagaagct
    50101 gttccaagag aaatttctcg ctttttttcg ttggcatagc gaatcacttt gtaaatcatc
    50161 gactttggca attgattctg atataagacc ttatctcttg ttaagatata ttggccattg
    50221 taagtaacgg caaaatctaa tccaaaattt tctagaaaag gttgcacaaa tcccggtcca
    50281 cgaccagttg ctaaaccgac cataatgcct tgttttttga gttgttggat ggctttttgc
    50341 gttgtttttt ggatattttt acgatcattg agaagggtcc catcaatatc aaaaaagact
    50401 gcttttactg tcaaaacctt cttttgcctc ctgtgtttat gatagaatag attataccat
    50461 aaataaaagg aagtttgaca atcaaatgaa aaaaatccta gtcttacaca ctggtggaac
    50521 catttctatg caagctgata actctggtag ggttgttcca aatcaagata atcctatgac
    50581 gaaaatacat gctgcagccc aagatattca gcttaccgtt agtgattttc taaatcttcc
    50641 gagtccccac atcacgcctc accacatgtt atctatttat catcatattc aagaaagaac
    50701 tgatgtcttt gatggtatag tcatcacaca tggaacagat accttagaag aaacagctta
    50761 ttttttagat accatggcat tgcctactaa tatacctgtt gtcctaacag gtgctatgag
    50821 atcttctaat gaagttggta gtgatggcat atataattac cttaccgcac ttagagttgc
    50881 aagtagtgat aaagctaaag aaaaaggggt acttgttgtt atgaacgatg aaatccatgc
    50941 tgctaaatat gttactaaaa cacatacaac caatatttca actttccaaa cacccacaca
    51001 cggaccgctt ggtatcatca tgaaaaatga cctacttttt ttcaaaactg ctgaacctcg
    51061 tattcgtttt aacttgagat gcatttctgg aaccatcccc attatcaaag catacgcagg
    51121 tatgggcgat ggtagtatct tgagtctatt aactccaggt agcattcaag gtctagttat
    51181 cgaagctcta ggggcaggaa atgtcccacc attagcagtt ggggagatcg agcacttaat
    51241 tactttaggt attcctgtcg ttcttgtttc ccgttgtttc aatggtatgg cagaacctgt
    51301 ctatgcttat gaaggtggtg gtgcgatgct acaagaagca ggtgttatgt ttgtaaaaga
    51361 attgaatgct ccaaaagccc gtctaaagtt attaattgct ctcaacgccg gacttactgg
    51421 tcaagagcta aaagattata ttgaaggata atctagcttc ctgtagaaat gtcccactaa
    51481 aacatattag tgggacattt ctagtacttt aagctttaaa ttaggacatt tcctaaatgt
    51541 ctataataaa caactatgtt tcaaactatg agattgtgca ctcataatca tttctataac
    51601 agtttgagac cagtattcca ataaatccaa ctcttagcaa tcagatactg ggtaaacaag
    51661 tctttatttt gtctcattaa gtatgagctt acttgaataa taacaaaact acttgctcat
    51721 ccttttttag taatgatgaa gacgaccttt ttctaagaac ttctttgtct tttaaaataa
    51781 acaaagcaca tattaccctt tattttagtt ctcgtttgga aaaaagaaag acattgccta
    51841 aaaaataaca aagagttaaa ccaaaggcca ctaatatgct agtactagaa aggtgtttat
    51901 caccaagaga caaggatagg tgtttaaaca tcaaaactgg gctaatatct aacttaaaaa
    51961 aatggtttgc taaagtagca gatactttat caaaaagaag aacataaagt atataagctg
    52021 tgattgactg ataagtttta cgaagtatat taaacaaaaa ttgacacaaa gcaataatag
    52081 caatataaaa aggcagttgt ttaatcatcc gatctatgac tattccatag tatgcttgac
    52141 cagtaaataa atgaaatgct aaagcactaa gaagataagt taaactaata aataaaagag
    52201 ataagccaaa actaactagc agtttataga ttataattaa agtacgattt tgttgtttga
    52261 ccacaacatt attaatcgta cggtagttat agtcatcact aaaaaagata cgggctggtg
    52321 ttaaaaagaa aagcgtcaca aaatcagtaa taatattaat gatttgtatc atgatgactt
    52381 ggttaggtgt cttgcgaaaa ctataggcta caccaacagc aatgacaaca agtagcatac
    52441 aagaaaatag agctaaacgc tcttggcgta tccgaaataa atctgcttta agataggaaa
    52501 tcataaaaac ctctttctaa attaatggtg acgctgcatc tttacctaac aaatcgaggt
    52561 aataatgttc aaagctcact tgatgatgat aaatgtcaaa aatctcaaca ggcagatcta
    52621 gaacaatttt gataagctcc attactgata aagttggttt tattagtagc atctgaccat
    52681 cagtctcaac tctaagcccc aattctaaaa gtctattttt taccagctga tcatcgcttg
    52741 tatgaagggc aatttgtact tttacttgag ctttaagctc tgctttgtcc atactcttaa
    52801 taactttgcc tttatgcata atcacgtaac gatcaacaac taagtctaat tctgataaaa
    52861 tatgactgga aatcaaaatc gtaataccat agcaatctct taggttcaaa ataatctgac
    52921 gcatttcttt gattcctgct ggatcaagac cattaatagg ttcatctaag attaaaaatt
    52981 ctggaaaatc cagtatcgaa agaccaatag ccaaacgttg gcgcatcccc aaagaataat
    53041 ctttcacctt tttctttttg ctcacttttt ctaacccaat aagttccaaa acctcatgta
    53101 tgcgctcttt tgcatcagct aatctcaatt gcaacgctgc atagtaaaga ttatcatgag
    53161 ctgtcatatt gggataaagt gtcggtgact caataattga tcccattcga tagggttgta
    53221 actgtttgat ttgccctgaa tcttttccaa ttaggccaga taaaatacgc attaacgttg
    53281 tctttccagc accattttga cccacaaggc cgcaaatttc tcctttgtaa atatcaaaag
    53341 agatatcact taaaacctga tttttaccat aggatttatt tacttgctca atacttagta
    53401 acattgattg ctgtgtcatt ttccgctcct tttttgtact tatcgattaa tacaatatct
    53461 tacacataat aacatctgta aacggttgtg acaagttctt ctttttatta aaaaaatata
    53521 aataagaatt t
//
LOCUS       DAUCXI010000008        52852 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.008, whole genome shotgun sequence.
ACCESSION   DAUCXI010000008 DAUCXI010000000
VERSION     DAUCXI010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52852
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.008"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            143..3217
                     /locus_tag="VGY43_000485"
     CDS             143..3217
                     /locus_tag="VGY43_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ4301701.1"
                     /translation="MTKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDEIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPAATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNALMSQGRLESICL
                     EPFNRQESLAYISSQLGSQPVTEEEMEHLYQASQGNPFFLSEYTQALLRHEKFVPLTP
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYYRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDHQRLMEE
                     QFDKIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVAANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQFEKAVTY
                     QKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDEGLVFYLMAVVKYQLIFQGA
                     TLSQQEKEMADHLLSESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(3248..4234)
                     /locus_tag="VGY43_000486"
     CDS             complement(3248..4234)
                     /locus_tag="VGY43_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginase family protein"
                     /protein_id="HEQ4301702.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGIDPN
                     LAVLVLQHIAASRKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHS"
     gene            complement(4421..5962)
                     /gene="hutH"
                     /locus_tag="VGY43_000487"
     CDS             complement(4421..5962)
                     /gene="hutH"
                     /locus_tag="VGY43_000487"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HEQ4301703.1"
                     /translation="MTRVINLDGESLTLEDVIAIARQGVACRIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAIGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLLEGSQNTTVATQSRV
                     QDPYTLRCMPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDL
                     KPENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASTVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(5974..7317)
                     /locus_tag="VGY43_000488"
     CDS             complement(5974..7317)
                     /locus_tag="VGY43_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEQ4301704.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRDPEKNVPRALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPATIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFENLAKLSVVFRFFQYIPTALAVMKLRKDAPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPEEQI"
     gene            complement(7537..8133)
                     /locus_tag="VGY43_000489"
     CDS             complement(7537..8133)
                     /locus_tag="VGY43_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HEQ4301705.1"
                     /translation="MTKVTIKAPSDYLQTDWSGGETNQLFLYPEDGDYKKREFSYRLS
                     KSTVALRQTTFTLLDGYHRILMTLDKPITLSDLSHAKEISLTPFEPYAFEGDTRIVSR
                     GICQDMNLMYDDQYQGQLLPVWSDTLFEAPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVIEQEASLSDLKVCLNQTSPAQTPVAVWAGLWYKT"
     gene            complement(8155..9828)
                     /locus_tag="VGY43_000490"
     CDS             complement(8155..9828)
                     /locus_tag="VGY43_000490"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ4301706.1"
                     /translation="MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDAR
                     QLVALKGKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGEKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKA
                     RLEKIIIGYNYQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRA
                     LKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVTLAEQDNQFRFVYEEDDSIETKLT
                     KIVTKVYGGKGITLSPAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFT
                     VTISNLKVSAGAGFIVALTGTIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(9846..10472)
                     /locus_tag="VGY43_000491"
     CDS             complement(9846..10472)
                     /locus_tag="VGY43_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HEQ4301707.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQVIIEDLHTKSSRLQQDLLDAIDKDTEAFNLVSAVFDMPKETDADKA
                     ARRTGMQKALKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     GAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(10483..11382)
                     /gene="ftcD"
                     /locus_tag="VGY43_000492"
     CDS             complement(10483..11382)
                     /gene="ftcD"
                     /locus_tag="VGY43_000492"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HEQ4301708.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGVTAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEIIGLAPAKALIDV
                     AEYYLQVEDFDYHKQVLENHLLG"
     gene            complement(11470..13500)
                     /locus_tag="VGY43_000493"
     CDS             complement(11470..13500)
                     /locus_tag="VGY43_000493"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002914331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HEQ4301709.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRFRPKDRIYGKPIDEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFQSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKAVAI
                     IAEVDQSRIETRHSQGWVSQIAESPEEALQLAQKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGKHEDLVTTDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTIALKFNELVRKGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVNQLFQ"
     gene            13790..15055
                     /locus_tag="VGY43_000494"
     CDS             13790..15055
                     /locus_tag="VGY43_000494"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HEQ4301710.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGDPKAYLDVIIKDMLPVVKEKNLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITNDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYLFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(15113..16645)
                     /gene="ahpF"
                     /locus_tag="VGY43_000495"
     CDS             complement(15113..16645)
                     /gene="ahpF"
                     /locus_tag="VGY43_000495"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEQ4301711.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHDSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQIAGPLSEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTNNMTIIKNVATKDIVGEDHVTGLSYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(16666..17226)
                     /gene="ahpC"
                     /locus_tag="VGY43_000496"
     CDS             complement(16666..17226)
                     /gene="ahpC"
                     /locus_tag="VGY43_000496"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEQ4301712.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYKTLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            17632..17702
                     /locus_tag="VGY43_000497"
     tRNA            17632..17702
                     /locus_tag="VGY43_000497"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17664..17666,aa:Cys,seq:gca)
     gene            18211..18414
                     /locus_tag="VGY43_000498"
     CDS             18211..18414
                     /locus_tag="VGY43_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEQ4301713.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            18610..19071
                     /locus_tag="VGY43_000499"
     CDS             18610..19071
                     /locus_tag="VGY43_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEQ4301714.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            19071..21515
                     /locus_tag="VGY43_000500"
     CDS             19071..21515
                     /locus_tag="VGY43_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ4301715.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKPPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSHGKLTFHIA"
     gene            21693..21983
                     /gene="groES"
                     /locus_tag="VGY43_000501"
     CDS             21693..21983
                     /gene="groES"
                     /locus_tag="VGY43_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEQ4301716.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK"
     gene            22019..23650
                     /gene="groL"
                     /locus_tag="VGY43_000502"
     CDS             22019..23650
                     /gene="groL"
                     /locus_tag="VGY43_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEQ4301717.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF"
     gene            23902..24147
                     /locus_tag="VGY43_000503"
     CDS             23902..24147
                     /locus_tag="VGY43_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4301718.1"
                     /translation="MNHFGEIFKTFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTI
                     STFMLILDESNMSIDEFMYAVHDFHRDDTTQDSDGLK"
     gene            complement(24852..26351)
                     /locus_tag="VGY43_000504"
     CDS             complement(24852..26351)
                     /locus_tag="VGY43_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ4301719.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGEKWKDPSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGISMSATVSASANDAIQKIDPYVKNGLAESSMASVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVAKKAKSYTEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGGVMWLSIGSPRNAPYLPYLGNISRTYEAY
                     QEKSTQYNDKSWYWTVSHINDLVAAHPKPFGTKVIDEMKGLEKTWIAEQDKSTKEISD
                     LVVSDPKAAQEKADKISLDRAEKTFKRLKAIEAKLVEEKPKNKKGLNRS"
     gene            26598..28238
                     /locus_tag="VGY43_000505"
     CDS             26598..28238
                     /locus_tag="VGY43_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301720.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNHKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDNSTDPEQHTSGHINQDLIGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDQKGNRSKETRTAKISKVEDKGNGFYLYMPDPGSDISALVPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            complement(28327..29328)
                     /locus_tag="VGY43_000506"
     CDS             complement(28327..29328)
                     /locus_tag="VGY43_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ4301721.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHPVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLNCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKNPLTQEDICVQAKSATFDAVLNAQKARK"
     gene            29904..30284
                     /locus_tag="VGY43_000507"
     CDS             29904..30284
                     /locus_tag="VGY43_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ4301722.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            30323..32659
                     /locus_tag="VGY43_000508"
     CDS             30323..32659
                     /locus_tag="VGY43_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ4301723.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKTRLTPQHNQKQYSPNANH
                     LDSSATKNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            32708..32860
                     /gene="rpmG"
                     /locus_tag="VGY43_000509"
     CDS             32708..32860
                     /gene="rpmG"
                     /locus_tag="VGY43_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ4301724.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            32874..33050
                     /gene="secE"
                     /locus_tag="VGY43_000510"
     CDS             32874..33050
                     /gene="secE"
                     /locus_tag="VGY43_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEQ4301725.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(33287..34060)
                     /locus_tag="VGY43_000511"
     CDS             complement(33287..34060)
                     /locus_tag="VGY43_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEQ4301726.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLIDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLADYQAVFLNHNIHCYF"
     gene            34186..34932
                     /locus_tag="VGY43_000512"
     CDS             34186..34932
                     /locus_tag="VGY43_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ4301727.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLDVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKRNIKIITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSASGLVLDFVS"
     gene            34948..35928
                     /locus_tag="VGY43_000513"
     CDS             34948..35928
                     /locus_tag="VGY43_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEQ4301728.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRQQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            36216..36536
                     /locus_tag="VGY43_000514"
     CDS             36216..36536
                     /locus_tag="VGY43_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ4301729.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLIKEIIDLRKE
                     LATK"
     gene            36564..36872
                     /locus_tag="VGY43_000515"
     CDS             36564..36872
                     /locus_tag="VGY43_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ4301730.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDKSEAICKDNDIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            36882..38186
                     /locus_tag="VGY43_000516"
     CDS             36882..38186
                     /locus_tag="VGY43_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ4301731.1"
                     /translation="MAKMNMQNIIKPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSDVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGIIGAIVIGLTVGAVYTTFIR
                     RHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLVYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIVSGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQASEES"
     gene            38397..40814
                     /locus_tag="VGY43_000517"
     CDS             38397..40814
                     /locus_tag="VGY43_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEQ4301732.1"
                     /translation="MTETKSPYFGHLTDRMTHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFALNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAKTAKPERQAELLDIARICDKVPYEPAKTFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDSIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGYGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTPEELWQALESDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            40827..41495
                     /locus_tag="VGY43_000518"
     CDS             40827..41495
                     /locus_tag="VGY43_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEQ4301733.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVIAQDYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAINRENA
                     NSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RKSI"
     gene            41552..42640
                     /locus_tag="VGY43_000519"
     CDS             41552..42640
                     /locus_tag="VGY43_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEQ4301734.1"
                     /translation="MKVFASPSRYIQGKNALFTNAKTLKQLGDSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMTGE
                     TIHQMPFVISPEDVAAALVAVDAYVTSR"
     gene            complement(42722..43231)
                     /locus_tag="VGY43_000520"
     CDS             complement(42722..43231)
                     /locus_tag="VGY43_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEQ4301735.1"
                     /translation="MSTDHHLREVSYQLLAERGGSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNAIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGYSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            43595..44410
                     /gene="sdaB"
                     /locus_tag="VGY43_000521"
     CDS             43595..44410
                     /gene="sdaB"
                     /locus_tag="VGY43_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HEQ4301736.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            complement(44651..45493)
                     /gene="ropB"
                     /locus_tag="VGY43_000522"
                     /gene_synonym="rgg1"
     CDS             complement(44651..45493)
                     /gene="ropB"
                     /locus_tag="VGY43_000522"
                     /gene_synonym="rgg1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="RopB (Regulator of Protease B) is a paralog of the
                     quorum-sensing transcriptional regulators Rgg2 and Rgg3,
                     which bind short, hydrophobic peptides encoded by genes in
                     their respective vicinities. RopB binds the leaderless
                     short peptide SIP (SpeB-inducing peptide), with sequence
                     MWLLLLFL; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     RopB/Rgg1"
                     /protein_id="HEQ4301737.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTKQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            45992..46162
                     /locus_tag="VGY43_000523"
     CDS             45992..46162
                     /locus_tag="VGY43_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301738.1"
                     /translation="MDNPKKDKGLSLGVVDPITILITESVINKMRTVPYHLKKLSSTT
                     YCLLADLAYQSA"
     gene            46434..47630
                     /gene="speB"
                     /locus_tag="VGY43_000524"
     CDS             46434..47630
                     /gene="speB"
                     /locus_tag="VGY43_000524"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HEQ4301739.1"
                     /translation="MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWEAQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            47632..47937
                     /locus_tag="VGY43_000525"
     CDS             47632..47937
                     /locus_tag="VGY43_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HEQ4301740.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHS
                     GGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMIEAYQTQISSLD"
     gene            48422..49351
                     /gene="prsA"
                     /locus_tag="VGY43_000526"
     CDS             48422..49351
                     /gene="prsA"
                     /locus_tag="VGY43_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ4301741.1"
                     /translation="MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTTAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAPK"
     gene            complement(49628..49864)
                     /locus_tag="VGY43_000527"
     CDS             complement(49628..49864)
                     /locus_tag="VGY43_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301742.1"
                     /translation="MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPTAHGPCD
                     DTHQLLEDKSLSDDYLISTSAMRHLWYWGYSQIG"
     gene            50288..>52852
                     /locus_tag="VGY43_000528"
     CDS             50288..>52852
                     /locus_tag="VGY43_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ4301743.1"
                     /translation="MTNCKYKLRKLSVGLVSVGTMLIAPTVLGQEVSVSTETSASTST
                     STASAGTSTSETAASGTASGTNGASSVTSSEGSQSSESAPASPQPQAQTAVASSSSSS
                     NANASSSSDGKAPQAASTTSSSTPAAASSNGISQGTSAEAETPMMEVEQYTVGNKTTE
                     LNIKDGAQLKNGSKVDKDTKLIRNRDGEQRDIVDIKREVKTNADGTVDVTVTVTPKEI
                     DKGADVMALLDVSKKMTEDDFNNAKDKIKKLVTTLTSKSPDSQPNHNARNSVRLMTFY
                     RKVNDPIELNADNVDAKLDEVWKKAKEDWDWGVDLQGAIHKAREIFNKGKRKKSGKRQ
                     HIVLFSQGESTFSYDINDKDENDTVQKNRIAGKVTTSNPLFPWLPIFNHTNQKAEVID
                     DVDKLLGLAEKMGISLPDGLRAGVKAIGAGSSFLSTFTGSGLTEYLTLNEYRSDILKE
                     KQFDYTKRVGEGYYYHSYSKRTHGDKMPFEKQIREVLERFLPKIEDKEWPKKFIEIFG
                     LQEKEVNQIGVDVIMKVINSIFYKREYHYYNHNLSAIAEAKMAQKEGITFYSVDVTDS
                     DKASKRVKRQVGNEQSKKKKEDAEKDRNNKFDDYLKKMSEGGNFLSKVEERGKFKDTL
                     TELTIKDEFTNKVKVQEDSEGKKYKTGLISGTSNVTHTPAKTGFFSSNESLTWTISKE
                     QLKKAFEDGTSLTLTYKLKVENDKFKKSLEEDNKKKRAKRSAPTENENSVTEKIISNT
                     TTYKINEQKVEGNKFDDVNLTYSKFKVPVPQIDGQVIEPQAPKLPDLPPVIEHGPVLD
                     YTEESIYRLPLEHGSNAPDTQVTIEEDTVPQRPDILVGGQSGPVDITEDTQPGMSGS"
BASE COUNT        16334 a        10449 c        11155 g        14914 t
ORIGIN      
        1 atgaattccc ttattttcga gatgactagc ttctttgttt attggtaagt gttaagacaa
       61 gcttttgctc attttgggtg acacttgcca aatcgtttta tttaagatat agtgaacttg
      121 actaattttt ggaggcgttt tcatgacgaa gggtattcga tttcaattgc ttggcagtcc
      181 ccacattttt cttgatgaca aagaacaatt ttttgccttt gccaaagcaa atgctctcct
      241 ttattactta gtggttaatg gatctgttag ccgcgaggtg gcggcgagtc tactttggga
      301 aaataagaac acgcaaacag cgaaaaagaa tttacgaaac gctatctacc aggtcaataa
      361 agtcttgcaa gctgatgtga ttatttgtcc caatcgcaac ctgctggttt tgaataaaac
      421 acttgatatc aaaacagata ttaacctttt tctggctgat ccgctagctc acttagaact
      481 ctaccaaggg gagtttttgc agggctttta ccttaaaagt ggtgaggaat ttgatctttg
      541 ggtttcaaaa atgcgtatgc agtatgaaca ggtataccta aaagcgtgtt accaaaaaat
      601 tgaagaaaag ctctctttag atgccattga agatgtcgag gaacatttaa aacagcttat
      661 tgaacgtgat gaatttgaag agaaaaatta tcagctcttg atgaggcttt atcagcaggg
      721 gaattgtcct ggtaaggtca tcgaaactta ttatcagttg gctaatgtgt tggataagga
      781 gctagggatt cagccaagtt tgcaaagcca acagatttat caggaagtgg tcgctaaaga
      841 tcgtaatgaa cgcaaaatca agcatttttt gcgcaacagt aatcattttt tggggcggat
      901 tgatgagatt aagcagctgg aaaactattt tgccaactgt ttggcctgcc aagaggtagg
      961 agctctgctc ttaattggtg atacagggat tgggaaacga accctagcca gacaggtctt
     1021 agccaatcaa acccaaacgt ttcaaattgt cacagctaaa tgttttcgtg aagaggctat
     1081 ggattcctta ttgccttggc gtaatatctt agatggcctg ggagatttgg tgattcaaaa
     1141 ccgcttattg accaccaaag cttggaaggc tgctcttaaa cgctgttttc ctgcggcaac
     1201 catttttcaa gaagataaca accaaccctt tatcaaggac cacaccagct tgttggtttc
     1261 ctttattgtt gatattttac aacatttggc agaaatcaag gcgctggtaa tccttattga
     1321 ggattgtcat tggatggatg aggacagttt gaccttgttg caacgggtca tgaatcaatt
     1381 ggtccactat ccgattgctt ttgtcttgac caagcatcta ggaacgactc ctgagctcgg
     1441 tctttgtttg aatgctttga tgagtcaggg gcgtttagaa agcatttgtt tggagccttt
     1501 taatcggcaa gaaagtttgg cttatattag cagtcaattg ggtagtcagc cagtgacgga
     1561 agaagaaatg gagcacctct atcaagccag ccaaggcaac cctttctttt tgtcagaata
     1621 cactcaggcc ctactgcgtc acgaaaaatt tgtgccttta acgcctgcca ttaaggctaa
     1681 gttgggtctt aaactagcta atctaagtag tcgtgatgac gcattgttaa actatttgtc
     1741 ttgttgtcgg aggcctatcc ctctaaatac cctcgctcaa ttgatgttac tgcctttaga
     1801 agaagtgatc gagatggtgg ataatctggg gcactactat attttggtag aagaaagcgt
     1861 aggagaggag gtgttgattt catttcgtca gcgaattatt caactctata gttattaccg
     1921 tttatctttg tcaaaaaggc gtttattgca cggacaaatt gccaaacggt tagaagattt
     1981 actgcctatt ttgacaccaa gccctcactt attagatgac attgcttacc attatcagga
     2041 atcacggcag gtgattaagg ccttggaata caaccttaac tatctagatg ctaccttgcc
     2101 atttcagcat gagctgtttc ccatttattc aaagagtatt ggctccttgg aaaagtcaga
     2161 tcgtgaccat caacgcttaa tggaagagca gtttgataag attcggcaaa gcattgcgga
     2221 tttggaactg acctatgata ataaccgtga tttccagcag ttgcttattc gtttttctta
     2281 ccttgaaggc cgttatgata ttcgaacagg gaggtatcaa gaagggatta aacatattca
     2341 aaaggtcatc gctttggcaa ctgagctaaa acagccctcc ttcttgctag aaggctatcg
     2401 ccagttaatt cattactgta tccaagtgga aaacaagcca gaaatgcgtt attacactag
     2461 tctttcattg gaggcagcgg ttgctgctaa tcattttgag gccattgcga ttagtttgcg
     2521 gttaaacggt ctttatcatt tgattattgg ggagttaaat gaggcagagc gtctgcttca
     2581 acagtcgatt gacttcttta aggtgacgcc aggcttgcaa gctaactatg cgattcagat
     2641 tgctgctgcc ttagattatt tgggggagat tgcccagatt cgctatcagt ttgaaaaggc
     2701 cgttacttac caaaaacaag ccattgcctt gaccgaaaac aagccagctg agttatcggt
     2761 gagtattttt tatattggat tagggatttc ctacttttat ttagctgatt ttgaacaagc
     2821 tgagcaaatc ttgagtttgg ctaaggaagc tttggtcaat catagttatc cttggaaaga
     2881 aacgcaactt gaaatttacc tggccatgat tcaatggaaa aagggtaatt atcagccagc
     2941 cttgacccta cttgattaca gagaaacctt gatgtctagg tatcgcaatc cgcgtgatga
     3001 gggcttggtt ttctatttga tggctgtggt caagtaccaa ttgatatttc aaggagctac
     3061 cctaagtcag caggaaaagg aaatggcaga ccacctgttg tcagaatcct ttgagtatta
     3121 ttatgaaatt gctagtacta acctcaaccc ttaccgagat tgtcatttgg tgagtgagtt
     3181 gaacgatttg cgtcaacaat tatctgctaa aagctaagga aaaccctctg aagtgaatca
     3241 gagggtttta gctatgttgt gccataatct gtacgaggta aaagataaag gtggctgcta
     3301 aattggcggt gtggttatca atatcgtgtg gtggtgaaac ctcaaccaca tcaaagccaa
     3361 ctaattttct actagctgca atgtgttgca aaactaagac ggcaagattt gggtcaatac
     3421 cgagggactg gatagcacta accccaggtg cagcaccaac tgagaaacaa tccatgtcga
     3481 tagtcaggta gaccctttct tgcccttcta agaaacggtc aatggctcgg cagacctttt
     3541 gatgacccat ttggtagatg tcttgaccag tcaaaaattg aatgcccttg gattttgcca
     3601 caaagtcaaa taggaaaagg ttgttattat gttcttgaat gcctaaaacg aagtatttaa
     3661 agaggcgttt gtcagcaacc gcatcgtcaa acatttgtcg aaagcctgtc cctgaattag
     3721 ggcctgtttg gtcgtaaggc cttaaatcaa agtgggcgtc catattgatg acagctaggt
     3781 catcacttgg ggataggctt tggcgtaggc ctaagtagtg gccgtaggcg gtttcatggc
     3841 cacctcctaa gacgatgggt ttgagattga ggtcacacat ccgtttgatg gctttgctta
     3901 aactgttttg cagttgttcc aaagagcgat tggggccgtc aatgttaccc acatcgtaaa
     3961 ccataacttg gtttcctaaa tgccaaggga atttggcgag ctgggttcgt atagcagctg
     4021 gactttcgac cgctccgaca cgaccattat tgatataaac ccccttatca cttttaaagc
     4081 caatcaaggc aaaatgtgtc ccttcaaatg gggttagtga gctgtcgtta aggtcaagga
     4141 aagtcatgac catgccccat ttggcagtat ataagtcatc gtcgatccca ccatgataat
     4201 agctagtggt ggatgggtag taatcttcta gcatgcgcgt catctccttt aggattatga
     4261 tagcaaaata aaacttacag tcaactctct ataggctgtc atcactggtt tttaggaata
     4321 gcagagcaat aaaatcgtct gcttttggtc ccagttagtt agtctaaaga ggccatgacc
     4381 tctgccacag cccctctcag ttaaagaagt accttattca ctaaaattgg atactcaact
     4441 caactgcctg ctcaaccgct tcgaggaagc ttgggtcttc aatgactgtt gatgccttgt
     4501 ttagttcatc gtagatttcg atgtgtttat cgtgttcgat aaagttgact tccttgcgga
     4561 agagatcgta ggcaacctta gtccctttac ctagttcatg attttcaggt ttgagatcaa
     4621 gagcttggca ggctgccatg atttcagtag ccacgatgcg gcgagaattt ttaaggattt
     4681 caaaggcctt gcgagcagcg gtggtgccca tgctgacaaa gtcttcttgg ttctcacaag
     4741 atgggataga atccacactg gctggatgtg ccaaaacctt gttttcagaa gcaagagagg
     4801 cacaggcgta ctgggtaatc ataaagcctg aattgagacc tgggtatttg acaaggaagg
     4861 atggtagttt gctgagctgg ctattgacca aacgttccac acggcgttca gaaacatttc
     4921 caatttcaga aatggcaatg cctaagaagt caaatggctg tgccattggt tctccgtgga
     4981 agttacctcc tgaaataacg tggccatctt tacagataat tggattatct gtgacagaat
     5041 tgatttcaat gtcaactttg gatttgacat aggcgatact gtctttgcta gccccatgaa
     5101 tttgaggcat gcagcgcaag gtgtaagggt cttgcacacg agattgagta gctacggttg
     5161 tgttttggct gccttcaagg aggtttcgga tattgcgggc tgttgccaac tggccgcttt
     5221 gtgggcgaat ggtgtgaagg ttttcttcaa atggactagt aatcccgtta tgcacttcaa
     5281 gggatagggc accagctagg tctgacagtt tcaataattg aatggcgtca taggttgcaa
     5341 gggcaccgat tgcagtgaga acagttgttc cgttgataag ggcgagtcct tctttagcgg
     5401 ctaaagaaat cttgtcaata ccagctttat caagagcttc ttgaccagaa agaagctctc
     5461 ctttgtagta agctttccct agaccaagca taggaagcac catgtgagca agcggcgcca
     5521 aatctcctga agcccctaga gacccttttt caggaatgta aggatgaacc cctttattga
     5581 gcagttccaa cagcttttca atggtggata gacgaatacc agaataccct ttgacgagag
     5641 agttgatacg gatcagcatg atagctctca cggcatcttc tggcaatggg tcaccaaatc
     5701 cactagcatg ggtacgaatc aaattttctt ggagttggac tgtatcttct ggtgagatgc
     5761 tcacgttaca aagggatcca aaaccggtgg tcaccccgta aaccacccgt ttttcactga
     5821 caatgtcatc aacaatttta cgagaggcat tcacagcttc aatagcacta tcatcaatgc
     5881 gacaggctac gccttggcga gcaatcgcaa tcacgtcttc gagggtaagg ctttcgccat
     5941 ctaaattaat cactcttgtc atagtttttt ctcctaaatt tgttcttcag ggggcatttg
     6001 gtccatttgg tggttacgtc cgtgcataag gtagtacaca ctacttgcaa tgatgacacc
     6061 aactgcacca tagacaaagt tcattgggtt gtcaccccaa atcataacta aactaacgat
     6121 aactgcaaga atcgggataa tagggccaaa tggtactcgg aagatcacat tagcatcagg
     6181 agcatctttc cgtaatttca taacggctag tgctgttgga atgtattgga agaagcggaa
     6241 aacaacactg agttttgcta agttttcaaa tgagccagtg agtaggagta caatagcaat
     6301 tgctcctgaa accaagatag caacgagtgg cgcgccattt tgattttgct tggcaatagt
     6361 agctggtaag agcccttcat cagcaatggc agcaccgtaa cgtggcacca tgatggattc
     6421 tcccatgtta agacctgtaa tggaaattaa agcaccgatt gagaccatcc aagcgccagc
     6481 agggcctatc attttaacaa aggcatcttg aacaggtgca ttggtcatca tgatttgaga
     6541 gccaagcatg gcaatggttc caccgataat cagcatatat aagacagaga cgatactgat
     6601 tgatcctaaa agagcacgcg gtacattttt ttcagggtca cgcatttccc cagcgacaat
     6661 agagagggtt tcaaaaccga taaagccata aaagatataa acagcagtat tggagatagc
     6721 ccctaagagg ttagtccctg gttccaactg aacaaatggg gtaaagttag gaagcccgtt
     6781 tttgatgaag aaaagggtac aggcacaaaa ggcaacgatt ggaattaact tagcaatggt
     6841 ggctgtgatg gtgacaattt tagaggtttt caaaccagcg atattcatca aagatagtaa
     6901 gatgattaac ccaatgctaa gtggaatgtg ccaaccttca aaggcaggga aagtaatgat
     6961 aaacattctg gcaaacccag ctgccatggc tgcccaagcg aagatggtaa cggtccaacc
     7021 aaggaagcca acgttaaagc caataaaatc accaaaagct cgtttggaat attggaaggc
     7081 tccgccgttt ttcccaaaat aaccagagac ttctgcaaaa caaactgcca acatgatggt
     7141 caaaatagct gttccaaaca taacagcgat ggatgcaggg ccaaggccct tgtaaatggc
     7201 cctaggtaag agaaaaatac cagagccgat aacggcattg atcccgtaaa gagtggcacc
     7261 gctcaagcta aactttgcct gttctctttc ttgttcgttc atgtgatttg acgccataat
     7321 aatgctctcc tttttgtttg caaattgcgt tcaaatataa tggataaggt cgctaggaaa
     7381 tgaggagata gtcggtttag gagggtcctt cttgcaccta acgatagtga tgagctattg
     7441 gttagcgatg agaaataggt agccttttgt gatgatgtgt agtgatttca ttggagaaga
     7501 ataggcatga gtagtgtgat gcctatcttt atcccactaa gtcttatacc ataagcctgc
     7561 ccaaacagct actggagttt gggcggggct tgtttgattg aggcaaactt ttagatctga
     7621 aaggctggcc tcctgctcga ttaccaacaa gtgattggct tcaagctctt gattcgcctg
     7681 attggtcaca gaataagtca gtttgcttag ggcataaagc agttgacagt ccgctttagg
     7741 tgcctcaaat agtgtgtcag accagacggg taataattgc ccttggtatt ggtcatcata
     7801 cattaaattc atgtcttggc agattccacg actgacgatt ctggtatcgc cttcaaacgc
     7861 ataaggttca aaaggagtta gggaaatctc tttagcatga ctcaaatcac tcaatgtgat
     7921 gggtttgtct agggtcatta gaatcctgtg atagccatca agtaaggtaa aggttgtctg
     7981 tcgtagggcc acagttgact ttgagaggcg ataagagaat tctctctttt tgtaatctcc
     8041 atcttcggga taaaggaaca attggttggt ttcaccgcca gaccagtcag tttggaggta
     8101 atcagagggc gctttgatag ttacctttgt catttgttct ctccttgttt ccaattagaa
     8161 tagtcctgtg atgttgccct cctcgtcaat atcaatggtt tcgctggcag gtacttttgg
     8221 aaggccaggc atggtcatga tagtacccgt cagagcaacg ataaatcctg ctcctgcaga
     8281 cactttgagg ttgctaatag tcactgtaaa gtcagttggt gcgccaagtt ttttggcatc
     8341 gtctgagaag gaatattggg ttttggccat gcaaattggg tagttgccaa agccgaggcg
     8401 ttctaagtca gccagttcac gtttggctgc tgggctcaag gtgatgcctt taccaccgta
     8461 aactttggta acgattttag tcagtttggt ttcaatgcta tcgtcttcct cataaacaaa
     8521 gcggaattga ttgtcttgct cggctagtgt cacgactttt tcagctaatt cacggccacc
     8581 agctccgcca tttgcccaaa catcagaaat cacaacgtca acgccacgtt tgtcgcaggc
     8641 atcatagaca gcttgtaatt cagcatcggt atcaagcggg aatttattga tcgccacgac
     8701 aactggaagg ccatagacgt cttggatatt agccaaatgt ttgtcaaggt taggtaaacc
     8761 atccacaacg gcctgaacat tttcagtagc caggtctgct tttggcacac ccccatgcat
     8821 tttaagggca cgaatagtgg ctactaggac aacggctgct ggacgaaggc cggacatgcg
     8881 gcatttgatg tcaatgaatt tttcagctcc aaggtcagca ccaaatccag cttcggtaac
     8941 ggcataatca ccatatttca aggctagttt ggtggctagg acactattac agccatgggc
     9001 gatattagca aatgggccac cgtgaatgag ggctggtgtg tgttccaggg tttgcacgag
     9061 attaggatga atcgcatcct tgagcagtgc ggctagggca ccaccagctt tcaagtcttt
     9121 agctgttaca ggttcgcctt gatagttgta accgatgatg attttttcaa ggcgggcttt
     9181 gaggtcagaa atattttcgg ataggcacag gattgccatg atttcagagg cgacggtaat
     9241 gtcgtaacca tcctcacgag ggaccccgtt gaccttgcct tgcaagccgt caacaatatg
     9301 acgaagctgg cggtcattca tatccaccac acgtttccaa gtaatacgtc tggaatcaat
     9361 gcctaggcta ttgccatggt gaatgtggtt atcaatcaag gcagctaata agttgttggc
     9421 gacaccgatg gcatgaaagt cccctgtaaa gtgaaggttg atgtcttcca ttgggacaac
     9481 ttgcgcgtgg ccaccgccag cagctcctcc cttaacccca aaaacaggac caagagaagg
     9541 ttcacgaagg gcaataactg ctttttctcc aatggcagaa agagcatcta ccaatccaac
     9601 agaagtggtg gttttgccct caccagctgg tgttggtgag atagcagtga caagaatgag
     9661 tttgccatca ggtttgcctt ttaaggcgac cagttgacgg gcatcaattt ttgccttgta
     9721 cttaccatag agacagagcg cttccttgtc aatccctaat tgatcggcaa ccttactgat
     9781 aggttccata gtgacagagt tggctatttc aatatctgat aaaaccatag ttgctccttt
     9841 acttgttaaa caatatcgag aattttcgtg tagatgtcat ctgccaaatg acagcccttg
     9901 tctaataagg cttgtccttt ttggcgatag tcggtaacaa agtcttcatc tttgatgcca
     9961 gacagattaa tcaaaacatt caaccaagcg ccttgtaaac ctgcttttaa gtttaaagca
    10021 gcaactccta agtcgctagc agcatttgta ttagacttac cgacagctgt tgcagtgatc
    10081 tcaagtgctt cgaccatgag ggtcatcatc tcaaaaggtg attgtgcagc tgttttcaag
    10141 gccttttgca tgccagttcg tctggcagcc ttgtctgcgt cagtctcttt tggcatatca
    10201 aaaacggcag aaaccaggtt gaaggcttcg gtatctttgt caatggcatc taataagtcc
    10261 tgttgcaagc gactactttt ggtatgaagg tcttcaatga taacttgata atcagcatac
    10321 tttttcttac caagagtcaa ttcacagacc atcttggtta aggaaatgcc attagcgcca
    10381 gagagagcag cagcagaacc accacctgga gcaggggcat ctgagccaag gactttagcg
    10441 aaatctgtta agcttaaatc aactaaaccc ataagacacc ccctagccta ataaatgatt
    10501 ttctaacact tgtttatggt agtcaaagtc ctcaacttgc aagtagtatt cagccacatc
    10561 gattaaggct ttggctggcg ctaagccgat gatttcagaa ccaataacat tcacaccgta
    10621 gcgacgcgct tcaaatttga tggtttcaaa agtacggtaa agagaacatt tttcaaagtt
    10681 aaccatgttc atggagactt gggcaatatg acggtcttct aacatgacac cgatggcttt
    10741 acaatatttg tagccaccac ctgaaccgcg gataatttta gcaattttat gagcaatgtc
    10801 gatattgtca gtatccaaat taacattgaa agcaaccaat ggcatgcgag caccaacggc
    10861 agttacccca gcagttgggt gaatcttacg atctccgtaa tcaggtgccc aatcctcttc
    10921 caacagtttt tctggcatgc cttcgaattg tcctttacgg actttggcca ggttttgacg
    10981 ttctggacgt gtggcagaat cttcataaag gaagattggg attccaagtt cacggttaat
    11041 ccgttctgcg acttgtttgg aaatttcgac acattcttgt gtagtgatgt ctttgatcgg
    11101 gacgaacggg cagacatcgg ttgctcccat acgagggtgt tcaccatgat gtttggtcat
    11161 atcaatgttt tcagaagcgt atttcaccag ttggaaagct gcttcttgaa tagactggtc
    11221 atctccaact aaggtaaaca cgctccggtt gtggctcgca tcagaagagt agtcgaggag
    11281 ggtcactcca ggaatacttt tggccgtcgc taccaagccg tcgataacag cctgattttg
    11341 gccttctgag aagttgggaa tacattcaac aattttcgcc atgttaatct ccttttatgt
    11401 cattgagtta ctcattaagg gaatgggtta cctattatag ataacgctta catttttatc
    11461 tagctgcttt tactgaaata attgatttac cgctgaagtc acaaggtcat cgtcagccaa
    11521 atatggaata gtgatgtgat cagtacctgc atggaggcgg ttgtattcaa tagcggtttc
    11581 aatagcgtgc tcattgcgag cccaattgcg acgagcaaca ccacccatgg tgtcccaagc
    11641 aatagcagat ttaataatct catcaatgcg ttcgctacca tctagaacaa gtccaaagcc
    11701 gccgttaatg gctttaccga taccagttcc gccaccgtta tgaagagcca ctaaactcat
    11761 accacgcgca gcgttaccag cgtaacattg aactgccata tcacaggtga cattggaacc
    11821 gtctttaatg tttgaggttt cacgaaatgg tgagtcggta ccagacacgt catggtggtc
    11881 acgaccaatc atgacaggac caatcttgcc tttgcggacc aattcattaa atttaagggc
    11941 gatagtcaca cgaccgatac agtcttggta aaggatccgg gcttgggtac caactacgag
    12001 ttgatttttc tcagcatcac gaatccagtt gtagttatca cggtcttgat agcggcggtc
    12061 aggatcgata gcttccatgg cagctttgtc agtagtcacc aagtcttcgt gtttaccact
    12121 caagcagacc caacggaaag gtccatagcc atagtcaaaa agcataggtc ccatgatatc
    12181 ttccacatag gatggccaga taaagccgtc tttgtcgtta cgaccattct tagaaatttc
    12241 tgtaatacca gagtcgtaaa cagacttcat aaaggcattg ccgtagtcaa agaaataggt
    12301 gccattttca gttaacgtct taatagcttc aaaatgccgt gccaaggtat catcaaccat
    12361 ttggtggaag gtatccttgt cttctgccag gagccgggtt ctttcgtcaa agctaatacc
    12421 tactgggcag tagccaccgt cataaacgtt gtgacaagag gtttggtcag acaaaagatc
    12481 aacatgaatc tgcttgtcat tgacgtattc taaaaggtca acaatattac catggtaagc
    12541 aatcgaagtg gactccttag catctatggc tttttgggct aattgcagag cttcttcagg
    12601 gctctcagca atttggctaa cccagccttg cgaatgacgg gtttcaatcc gagattggtc
    12661 aacttcagca ataatggcaa ctgctttagc aatttcagca gccttacctt gtgccccact
    12721 catgcctcct aaaccagatg agataaagag tttaccggtc aaatcaccat cgtcagccac
    12781 tccaagtttg agacgaccag catttaagag agtattaaat gttccatgaa caatcccttg
    12841 tgggccaata tacatccaac cacctgcggt catttgacca tagttggtga cacccatctc
    12901 ttcagcgatt tcccagtctt tcatgttgtc gtattcacca accaaaaggc cattagtaat
    12961 aatcacacga ggggcttcag gtttggattg gaaaagacca acgggatgac cagattcaac
    13021 caccaaggtt tgttcatcag tcatgacctc taggtatttt ttaatcaaac aatattgcat
    13081 ccagttggca caaacagaac cagtttctcc ataagtgact agttcgtaag ggtacaaggc
    13141 aatctcaaaa ctcaagttat tgtcaatcat gacctgcatg gccttggcag ctgtacaatt
    13201 tcccttgtac tcgtcaatgg gtttgccgta aatgcggtct tttggtctaa agcggtagcc
    13261 ataaatacgg ccacgggttt tgagttcttc caaaaattct ggaatgactt cttcgtggaa
    13321 ctttgtaggt acatagcgta gggcattttt taaggcaatt tcggtctgag cctgggtcaa
    13381 tcgaaaacct ctgtctggtg ctcttcggat accttctttg aacacagtct tttccggtaa
    13441 aacatcgtct aacttaacag tcatagcggc agctatgtca gtttcactgt aaaatgacat
    13501 agaaaactcc tcctcaactc ctttttattg tcgagattag tctaacttag cctagtctat
    13561 aaaaagtcaa ccacgctttg aaatgcgaaa aaagtctaaa aaaaatcaaa acctcatttt
    13621 ttgactaaaa tttgacgctt aatcagtaca cttgaggtat gacagataaa gtcagtcaga
    13681 ggttaattgt tgttaccaaa gttgcaaaga tcgcaactat tgagtgggtg aggggggcta
    13741 gtaatggcta ttaatcagtt gacaaacgat gttaaaaaag gaggttttta tggttgctga
    13801 tgtcttatta acacatttta atcaactatt ttgtctaaat gatccaggtc atcctttaac
    13861 tggtcaagaa atgaaaaaag ccactatcgt tgaagatggc tatatagcca tcaaagacgg
    13921 cctcattgtg gctcttggtt ctggtgaacc agatgctgag cttgtcggtc cacagactat
    13981 tatgcgttct tataaaggta aaattgcaac gcctggtatt attgactgtc atacccattt
    14041 ggtctatggt ggcagtcggg aacatgaatt tgccaagaaa ttagcagggg tgtcttactt
    14101 ggatatttta gctcaaggtg gtggtatttt aagcacggtg agggccactc ggtcagccag
    14161 ctttgacaac ctttatcaaa aatccaagag attgctagac tacatgttgc ttcatggagt
    14221 gactaccgtc gaagcgaaaa gtggctacgg ccttgattgg gaaacagaaa aacgccaact
    14281 ggatgttgtt gctgctttag aaaaagacca tcctattgat ttggtgtcta cgtttatggc
    14341 agcccatgcg attcctgaag aatacaaggg ggatcctaag gcttatctcg atgtgattat
    14401 caaggatatg cttcctgttg ttaaagagaa aaatctggca gaattttgtg atattttctg
    14461 tgaaaaaaat gtttttacag ctgatgagtc ccgctatctg ttaagcaaag ccaaagaaat
    14521 gggcttcaag cttcgtattc acgcagatga aattgcgtct ataggcggag ttgatgtcgc
    14581 agcagagctc agcgcagtta gtgcagagca tttgatgatg ataacaaatg atggtatcgc
    14641 taagttgatt ggtgctggtg ttattggtaa tttgcttcca gccaccacct ttagtttaat
    14701 ggaagacact tatgcccctg ctcgcaaaat gatcgatgcc ggcatggcca tcaccctctc
    14761 aacagatagt aatccaggca gttgcccgac tgctaacatg cagtttgtga tgcaattagg
    14821 ttgttttatg ttacgtttaa caccgattga agtcttaaat gctgttacca ttaatgcggc
    14881 ctactctgtc aatcgtcagg agagagttgg tagtttgaca gttggtaaag aagcagatat
    14941 tgccatcttt gatgccccaa atattgatta cctattttat ttctttgcca ccaacttgat
    15001 tcaccaagtc tataaaaaag gacaactcac agttgaccga ggtcgtattc tttaaaaaat
    15061 ttcaaaaaga agctttgagc gttagctcaa aacttctttt aaatatgctg ttttattgac
    15121 gaatcaagta gtcaaaggca ccgatggcag cagtagcacc agaccccatg gaaataatga
    15181 tttgtttata agctgaatca gtacagtccc cagcagcaaa gataccagga atattggttg
    15241 acccatgttt atccacaatg atttcaccgc ggtcggttag gttgacacca ctatctttga
    15301 gccaagctgt gtttggaaca agaccaattt gaacaaagac cccttcaagg tcaaggtgtt
    15361 tgtcttcacc gctatcacgc tcagtgtagc taagacctgt aacatggtcc tctccaacaa
    15421 tatccttagt agcaacattt ttgatgatgg tcatattgtt agtcttagct gcgcggtctt
    15481 gaaggacttt gtcagcttta agttcaggca agaattctaa aacgtaaacg tgtttagcaa
    15541 gaccagccaa atcaagggcc gcttctaaac cggagttacc accaccgata acagcaacat
    15601 ctttgccttc aaagagagga ccgtcacagt gagggcagta agtcacccct ttattacgga
    15661 attcatcttc accaggaaca ttaatgttac gccatttggc cccaagagct aagatagcag
    15721 ttttggcttg tagaaccgca ccattagcta gagtaacctc gatgttttct tttttctcaa
    15781 tagaagtagc tagttgtgct ttgataatat caacatcata agacttagta tgggcctcca
    15841 cttcggccat taattttggt ccttcagtgt aaagggtacc aatcatgttt tcgatgccga
    15901 cagtttccat gacctgacca ccaaaggttt cagcaagtaa acctgttttt agtcctttac
    15961 gagctgcata gatagcagcg ctattgcccg cagggccacc accaataaca aggacatcat
    16021 agaggccttt atcagcaaag gcttcctcag aaagtgggcc agcgatttgt tctaagagtt
    16081 gctcaatggt agcacgacca gaagtgaatt cttccccgtc taaaaagaca gtagggacag
    16141 acataatgcc tttggctttc acttcatctt ggaacatgcc gccttctacc atagtgtgtg
    16201 aaatcttgtc gttcaagacg gacataatgt ttaaagcttg aacaacatct gggcagttat
    16261 ggcaggttaa gctgacataa gtttcaaaat gcaacggacg gtcaatggcc ttgatgcgat
    16321 caataacatc ttgatccact tttggagcac gtccagatac ttgcaagaga gcaagaataa
    16381 aggacgtcaa ttcgtggcct aaaggaagac cagcaaagac aaccccacta tcgtgacctt
    16441 ttttcgcaac cttaaagctt ggttgtcggt ctaaagtgat gttttcaata gaaatacgct
    16501 cagacatagc agctatttct tccacaaagt ctttgacttt ttgagactgc tcattgtcac
    16561 caagggaaac ttgcaaaaca agatcagctt ctaacagggt gaggtattgg gcaagttgtt
    16621 ctttaatatc aggacttaat gccatagctt tcctcctaaa atttattaaa ttttaccaac
    16681 taaatcaaga cttggtgtca aagtttcagc gccttctttc catttagctg gacaaacttc
    16741 acctggatgt ttacggacgt attgggcagc gtgaatttta tcaatcaagg tgctagcgtc
    16801 acgtccaata ccatcagcat taatttccat catttggata ataccatctg ggtcaacgat
    16861 aaatgttcca cgttgagcaa gtccgtcttc gccaagcact tcaaaggctt gtgaaataag
    16921 gtgtgaaggg tcaccaatca tagggtatgt gatagtgcca accacatctg aatcatcatg
    16981 ccaagcttta tgaacaaaat gagtatcagt agagacagaa taaacttcta caccaagaga
    17041 ttttagtgtt ttgtattgct cttgaaggtc accgagttca gttgggcaaa caaatgaaaa
    17101 gtctgctggg tagaaacaaa aaactgccca ttttccttta acgtcttcat ttgtaacagt
    17161 gatgaatttt ccatcgtgat aagcttgagc tgaaaattca gcaatttctt ttccaattag
    17221 agacatatag ttgtcctcct tttttatagt tttatacttg tattataaaa gaacaacaag
    17281 attatgtcta ctcagaaacc cttgatttta ctgggaaatc agcgattgtt ttctgacaat
    17341 tcagttgtga aataaatcac attaattaaa atgattctaa ataagccgaa gacgccgtta
    17401 aatcaaaggt taatttaatt ataatctaca gaaaatataa ttgttattaa agcgtttaca
    17461 aaaaactttt ttgattccgt taaggcaact taatattatg gttacctaat cactaatatt
    17521 gtaacctatt ttggcatgag atcagggaat ggctgttata ttaattggat atgtcttgtg
    17581 caaatagtgc ttgacggatt tgtggaatta gggtaaaata atctttgttg tggcggtata
    17641 gccaagtggt aaggcacggc tctgcaaaag cttgatcgtc ggttcaaatc cgtctaccgc
    17701 cttttatata caaaacaagc cttgattaac ttcgtgaaaa cgttgttaaa tcaaggtttt
    17761 tattttttgc ggcaggataa aaaaagagaa aaaaaaaaat aaagtcggtc aaatttcccg
    17821 aagatgtctt ttagagcctg attattaggt atgaaaaata ctatggccaa aattggtaaa
    17881 cgattgcaaa taaaggtcag agttcttacc cccttaaacg atatgcgtta aaagttagtt
    17941 gaactgccgt gcaccttaac gatagacacg gtgatgtgag agcgagtaga gttgaatctc
    18001 tacttgttta ccttaccata gtcagcttta taaagtaacc acccattaca atgcaactat
    18061 attcttaatg tttttaagca tgttattgac aagtgttata aaatgtgtta ctcttagtga
    18121 gtaaattagt ttttgagtta gtatttgtgt ttcaacatct ttatttctct ctatttttac
    18181 aaatgatttt tagaaaggaa gtggatgtac atggcacaag gtacagtaaa atggtttaac
    18241 gctgaaaaag gttttggttt tatttcaact gaaaacggtc aagatgtctt tgcacatttt
    18301 tcagcaatcc aaactaatgg ttttaaaacg ttagaagaag gacaaaaagt ggcatttgac
    18361 gtcgaagaag gtcaacgtgg acctcaagca gtcaatatca ctaaattggc ctaatctggt
    18421 taaagtaact aaagagaagc agatgttgga aacaacaact gcttttttga tttctaccag
    18481 ttacctttaa tgattaagag ttgcgtttaa ggtcttgtat ttgttataat aatagtcagt
    18541 tttagtcaaa atgtattgac gtggtgctac taagttttta gagtagcccg caagcaaagg
    18601 agtgacagca tgccaaccaa aaatacttca gacagcattg aagagtatat taaagaatta
    18661 ttagctaagt caggaatagc agaaattaag cggtccatgc tagcagattc gtttcaagtt
    18721 gtcccaagtc agatcaacta tgtcattaaa acccgtttta cggagagtcg aggctatgaa
    18781 gtagagagta aacgaggtgg tggaggctat attcgtattg ccaaggttca tttttcagac
    18841 aaacaccatc tgattggcaa tttaatggca actattgaag actgtatcag tgagcaagtt
    18901 ttcacggact cgatacaatt gctttttgac gaacacttat tgacagagcg tgagggaaat
    18961 atcattttgg ctgtggcgtc tgatgatgtt ttaggaactg atggttcaac tattcgtgca
    19021 cgaatgctct atcgcttatt gcaacgaatt gacagaaagg gaagcaatta atgattatgt
    19081 attcaacgaa gatgcaagac atttttagac aggcgcagtt ccaagctgct cgctttgata
    19141 gccattgcct ggaaacttgg catgttttgt tagctatggt agctgtagat aattctttag
    19201 caaatatgat tttaagtgaa tatgatgccc aagtcgccat agaagaatat gaagctgcag
    19261 ctattttagc catgggcaaa ccccctaagg aacagttgtc tcgtgtagac ttcagacctc
    19321 aatctaaaac cttgactaac ttgttagctt ttgcgcaggc tattagccaa atcactaggg
    19381 atcaagaagt cggctctgag catgtcttat ttgctatttt attgaatcca gatatcatgg
    19441 cgagtcgttt gttagaaata gcaggctatc agataaaaga taacggcaat gggcagccgc
    19501 gattagctga cttgcgaaaa gcaatagaac gtcatgcagg ttacagtaag gaaatgatta
    19561 aggctattca cgaactacgt aagcctaaaa aaacgaaaac acaagggacc ttttcagata
    19621 tgatgaagcc accaagtaca gctggtgagt tgagtgattt cacaagagat ttgactgaaa
    19681 tggcaagaca aggtttgtta gaatcggtga ttggacgtga ccaagaagta tctcgtatga
    19741 ttcaggtact aagtcgtaaa acgaaaaaca atcctgtctt ggtaggtgat gcaggtgttg
    19801 gtaaaactgc gcttgcttat ggccttgctc aacggattgc aaatggcgct attccttatg
    19861 aacttaagga gatgcgtgtc ctagaattag acatgatgag tgtggtagca ggaacccgtt
    19921 ttcgtgggga ttttgaagag cgcatgaatc aaatcattga tgatattgaa gctgatggtc
    19981 agattattct ttttgttgat gaactacata ctattatggg ttctggcagt ggtattgaca
    20041 gtacacttga tgcggctaac attttaaaac cagcattatc gcgcggtact cttcatatgg
    20101 ttggagcaac aactcaagaa gaatatcaaa aacatattga aaaagatgca gctctttcgc
    20161 gtcgttttgc taaaatatta attgaagaac ctaatacaga agatgcttat cagattttga
    20221 tgggcctaaa attatcttat gagacctacc ataatgtctc gatatcaaat gaagcagtta
    20281 aaacagctgt aaaaatggca caccgttatt taaccagtaa aaatctccct gattcagcta
    20341 tcgatttatt agatgaagct agtgctgctg tgcaaaacat ggtgaaaaaa tcagcacctg
    20401 agactttaac accaatagac caagctctta tcaatggtga tatgaaaaaa gtatctcgcc
    20461 tcttagctaa agaagcaaaa ggtcagatga gaaaaccaac accagtcaca gaagatgata
    20521 ttttggcaac cttgagtaag ttatcgggaa ttccacttga aaaactgacg caagctgata
    20581 gcaaaaaata cctcaattta gaaaaagaac tgcataagcg tgtgattggt caggatgctg
    20641 ctgttacggc tatttcaaga gccattcgtc gcaatcagtc aggtattcga acaggaaaac
    20701 gtcctattgg atcatttatg tttcttggcc caacaggagt aggtaagaca gaactagcaa
    20761 aggcccttgc agaagttctc tttgatgatg aagcagcgct tattcgtttt gatatgtctg
    20821 agtacatgga aaaattcgca gcgtctaggc ttaatggagc acctcctggt tatgtcggct
    20881 atgatgaagg aggtgaactg acacagaaag ttagaaataa accttattca gtcttgcttt
    20941 ttgatgaagt ggaaaaagca catcctgata tttttaacgt tctccttcaa gtattagatg
    21001 atggtatatt gactgatagt cgtgggcgta aggtcgattt ttcaaatact attattatca
    21061 tgaccagcaa tcttggcgca acagccctgc gtgatgataa aacggtcggt tttggggtca
    21121 aaggcattca ccaagaccat caagctatgg agaaacgtat cttagaagaa ttaagaaaaa
    21181 cttaccgccc agaatttatc aatcgtattg atgaaaaagt ggtctttcat agtctgaccc
    21241 aagataacat gcgcgatgtg gttaaaatca tggtacagcc cctgattact acattggcag
    21301 aaaaaggtat tacccttaaa attcagcctt tggccttgaa acatttgtcc gaggtcggct
    21361 atgatgagca tatgggggca agaccattac gtcgaacgct gcaaactgag atagaagata
    21421 agctatcaga gcttatcctt tctcgagaat tgacaagtgg gcatacgcta aaaattggat
    21481 tatcacatgg caaattaacg tttcacatag cttaatttcc atataaaagg tggatcatcc
    21541 ttgatgtcac caaaaaaaga ggttattctt acaaaaataa cttctttttt cttgactatt
    21601 tttgaccaag tgataaaata gaatataaag ttagcactcg atgaatatga gtgctaactt
    21661 tactaaagat tcttttattg gaggaaaatt tcatgttaaa accattaggt gaccgtgtgg
    21721 tcgtaagatt tgatgatgaa aaagagcaga cagtcggtgg ttttgtcctt gcaggcactc
    21781 ataaagagtc aacacgaaaa gcgacagtcc tcgctgtcag tgaaacgggt gttcgcacta
    21841 ttacaggcga tagcgtgcta ccttcagttt cagtgggtca agaggtttta gttgaaaatg
    21901 ggcatgattt agaagtaacc gtagatgatg agaaagtttc tatcatccgt gaatctgaca
    21961 tcattgctat tgtcacaaaa taaaacgaca aatctctaaa tagaaagaag gattgaatat
    22021 ggcaaaagat attaaatttt cagcagatgc gcgtgctgcc atggtgcgcg gagttgatat
    22081 gttagcagat accgtcaaag taacgcttgg tcctaaagga cgcaatgttg ttcttgaaaa
    22141 agcttttggt tctcccttaa ttactaatga cggggtaacc attgctaaag agatcgaatt
    22201 agaagatcat tttgaaaaca tgggagcaaa attggtgtct gaagtggctt ctaaaaccaa
    22261 tgatattgct ggtgatggga cgactactgc aacagttttg acacaagcca ttgttcatga
    22321 aggactaaaa aatgtgacag caggtgctaa tccaattggt atccgtcgag gcattgaaac
    22381 agcaacagca acagctgttg aagccttgaa agccattgct caacctgtat ctggcaagga
    22441 agctattgct caggtcgctg cagtatcatc acgctctgaa aaagttggag agtatatctc
    22501 agaagctatg gagcgtgtgg gcaacgatgg tgtgattacc atcgaagaat ctcgaggtat
    22561 ggaaacagaa cttgaagtgg ttgaaggcat gcaatttgac cgtggttacc tgtctcaata
    22621 catggtcaca gacaatgaaa aaatggttgc agaccttgaa aacccattta tcttaatcac
    22681 ggataaaaaa gtgtcaaaca tccaagacat tttgccacta cttgaggaag ttcttaaaac
    22741 caaccgtcca ttactcatta ttgcagatga tgtggatggt gaagcccttc caacccttgt
    22801 cttgaacaag attcgtggta ctttcaatgt ggttgctgtc aaagcgccag gatttggtga
    22861 tcgccgtaaa gctatgcttg aagacattgc tatcttgaca ggtggtacag tgattacaga
    22921 ggatctagga cttgaattaa aagatgctac aatgacagcc cttggacagg ctgctaagat
    22981 tacagttgat aaagatagca cagtaattgt tgaaggttca ggaagttcag aagctattgc
    23041 taaccgtatt gcactgatta aatcgcaatt agaaacaaca acttctgact ttgaccgtga
    23101 aaaactacaa gaacgtttgg cgaaattagc tggtggtgta gctgttatca aagtaggagc
    23161 tccaacagag acagctttaa aagaaatgaa actccgcatt gaggacgctc taaatgctac
    23221 acgtgcagcc gttgaagaag gtatcgttgc tggtggtgga acagcactta ttacggttat
    23281 tgaaaaagta gcagctcttg aacttgaggg cgatgatgct actggacgta acattgtgct
    23341 tcgtgctcta gaagagcctg tacgtcaaat tgctttaaat gctgggtacg aaggctccgt
    23401 agttattgac aagttgaaaa atagccctgc aggaacagga tttaatgctg caacaggtga
    23461 gtgggttgat atgattaaaa caggaatcat tgaccctgtc aaagtaacac gatcagcgct
    23521 tcaaaatgca gcttctgtag ctagtcttat tttgacaaca gaagcagttg tcgctaataa
    23581 acctgaacca gcagcgccag cgccagcaat gccagcaggt atggatccag gaatgatggg
    23641 cggcttctaa gctctctata gcattaagga ttatgaaaaa gaagttgaga ctaaaggtct
    23701 gcttcttact atgaaaaaag aacaaagatt ggatttcgac tcatgatatc ccatctttgt
    23761 tttttttagt tgtgatataa aatgccaatc tttgtggtta cagactttta atgtattgga
    23821 aaatatattg tttttctttg tcatgtgcta tcatggagtc aatgaaaagt tattcccata
    23881 tatgcgtggt ggaggtctgt gatgaatcat tttggagaga tttttaaaac ctttagagaa
    23941 tcaaggggat tacgattaaa agatgtcgca aaggctggta tatcaacctc tcagctgtcg
    24001 cgtttcgaaa aaggggagac ggatttaacc atatcgacat ttatgctgat tttggatgaa
    24061 agtaacatgt ccattgatga gtttatgtat gctgtccatg attttcatcg tgacgacaca
    24121 actcaagata gtgatggctt gaagtagtta cttcatgctc aactagcatc aactgataag
    24181 aaggaaatgt tcacggatat cttttggcat atccagcatg tctaagtctg ctatggcatg
    24241 ccattttggg agtccctcac gcgactctgt cagtagctct ccttcaaagg attcacatat
    24301 aaagtcgtaa tagacatagc actctttttt tgtcaggctt gataaagcta gaaataccct
    24361 ttaattgaag gtttaaagct gtcagaccta tctcttcttt tagttctcat aaagccgctt
    24421 caaagaaaga ttcacagggc tcgactttac cttctggctg gccccatcct gggaagttat
    24481 cgtgttgtct atggagtcat aaaatcatat cgttatgttt gacacacata ttgccccagt
    24541 ctctaaccgt tgctatcacc agattcacca ccttttagta tagtataaga aaaaaggggt
    24601 gaaagaggtt tcttgttgtt tttttggctt aagatttctt taagtcttat ctagtatact
    24661 aatgtcattc cttaatagga taagtatttg gttgtagaag tatcgtctta aactaacgct
    24721 atctcaaccg attcccatct tattcacccc tcctataccg ataaggtctc acaaagtgtg
    24781 agaccttatt ttttgacttc agctctagtt atggagaaac ttgttgatac aagctttttt
    24841 gggttatggt attatgatct attcaagcct ttcttgtttt tgggtttttc ttcaactaac
    24901 ttggcttcaa tagcttttaa gcgtttgaag gttttttcag cgcgatctag tgaaatctta
    24961 tcagcttttt cttgagcagc tttggggtca ctgacgacta agtcactgat ttctttggtg
    25021 cttttgtctt gttcggctat ccaggttttt tccaagcctt tcatctcatc aatcacttta
    25081 gttccaaatg gttttggatg agcagccacg agatcattaa tgtgtgacac cgtccaatac
    25141 catgacttat cgttatattg ggtgcttttt tcttgatagg cttcataggt tctactgata
    25201 ttgccaaggt atggcaagta aggggcatta cgaggactgc caatagataa ccacatgaca
    25261 ccaccaccca attcagcagg gatgtctttt ttcagttgga aaatatgagc ttccatgaca
    25321 ttaggattgg aaataggata cgcatagccc ttaacagctt ttttggattt tggtttaccc
    25381 ttaccgtcta atgccatctg atcaagtggt ttaagatcaa gcccctcaaa acgattacgt
    25441 tgcagtttca tcgcatcttc tagactaaag gtcttatcag tgctttggag caactcataa
    25501 ttgctgtctt tataagttac ttttgaatca gggtcaagtg atttaatccc tgagaaagag
    25561 cgagagcggt tggcatcgtt tagtggcgga ttgtaagatt tggcaatatg aaatttacca
    25621 tcaacttcgg tataagattt ggctttttta gcgacttttt ccacatcttc tgaggcaatc
    25681 gtattttcct tatcgttgaa atcgacatgt ccgagataga aggtatttgg aaaaacagcg
    25741 tatttatcat ctgggaattt gatggcaacg tattggtgac cagagagaat ttccatgtac
    25801 cagatgccgt ctttgtcagc caaggtaaca atatttcctt cagcagctcc tttttcagtg
    25861 actattttag caatcaatgc gacaccttca cgggctgttt tgacacttgg taaaatgacg
    25921 ctggccatag atgattccgc taagccattt ttgacgtaag gatcaatttt ttggatggca
    25981 tcattagctg aagctgatac tgttgcagac atagagatgc caaactcatt aaaaccagct
    26041 tcgtcataaa cgcctttatt aggtgttaca tcaggaatcg cactatagcg ataagaatgc
    26101 tcaggcaatg ggtactcaaa accattagag gggtctttcc atttttcgcc agcaggattg
    26161 tcctttgcta gacgtacaat gaagttttta ttatgatgtg gctcaagatc ttctgttcga
    26221 ccataaagaa gagaaccgtc tttggttaaa tctttgccaa taataaaacc agtacaagca
    26281 taactaacac tttgaagcga aaaggctgtc agaatactta aaactccaag tgatattttt
    26341 ttgtttatca tgcgaatcct cctagtaaac gataacgctt tcacagacat tataaaatgc
    26401 tctttttaaa aattcaagtc ttttatgaag tgttttgaaa ttgttagcta tctaaatatt
    26461 atgagaatta tctcttgaat tttggcttaa cggcccctaa aaacgtatag gcagtgaact
    26521 atctaggttt cttcgaaaat ccattagcca tttatgatat aatagtaaag aaaaacatag
    26581 aaagttgggg tctgttgatg accaaaccat ttcatcataa gaaactaaaa caaataacta
    26641 taatagctgc aactagcctt tttttattcc tgatcggtgg tgctttttac tactctaaaa
    26701 atcattgtat taatgcctat cttaaagctc gatcagccca atcaggacca gtttttgaga
    26761 atatcaaagc gtatctagtc tgggatgata ctaatgagca gatcacaaat gacgaggcga
    26821 tgtatactaa gtttagaagg tatagtcaaa aagaattgag gcaaaaaaag caggatttaa
    26881 aagccgctag tcaagatagt gccgttcaag taaagtctgt tggtcgtcgt ttttggattt
    26941 ttcctgatta tcggattgcc ataaaaccca tggatttaac gataaaaacg aatgtacctc
    27001 aagcagacgt tcttttaaat cataaaaaag ttgctgtttc tgattcagaa cagttctcag
    27061 tcaagcttga tcggctacca acggcagaat ataccgcaag tatcagaggc aaacacaacg
    27121 ggcgaaacat taaagtcaac aaatcatatg atggtgataa tcccgtgcta gatttgagtg
    27181 tgtcttttag aacttttttg gtaacaagca atgctaagca aggagatctt tacttcgatg
    27241 ataaccatat tggcacatta aaagatggtc aattacaagt agaagattac cctgttacag
    27301 aaaacgcaca agcttatatg aaaacaacat tcccagatgg tgagttaaga tcacaaaaat
    27361 atgctctagc tgatgttgaa gaaggagcaa ccctggagat tttagttaca gatcttttag
    27421 aagaggacaa ggcaggggag ctattagtat cagcttttga tcagctgatg cactacctca
    27481 gtacaggtca agactcatct aacttacgta gcgtctttga ggcagggtct agcaacgcat
    27541 tttatagagg attgaaagag tccataaaag cgaaatttca gacagataca agaaaagcca
    27601 gccgtctcaa tattccatct atccttttga caacaatgac tcaagtgggt aaaacaactt
    27661 acgtgcttga tttcacagct acctacgaat ttttgtatga caactcaaca gatcctgagc
    27721 agcatacctc tggacatatt aatcaagact tgattggaaa agtgactgta aaaaaagttg
    27781 gacagcatta ccttatcagc cagtccggct ccaaaaatat tactgttgtt aaagaggaca
    27841 atcaactcaa agcgccatct gtctttcctg agtctatttt gggaacgtgg acaggccaag
    27901 ccaatggttt gagcatccat atgtctctag catcagatgg aacaattacg actaaagttg
    27961 aagatcaaaa aggcaaccgt tctaaagaaa ctcggacagc taaaattagt aaagttgaag
    28021 acaaaggcaa tggtttttat ctttatatgc cagatcctgg aagtgacata agcgccttag
    28081 ttccagaagg aggattgggg ggtgcaaatg tcaaatatgc ttatggtttc aaaatatctg
    28141 gtaaaacagc ctctccagtg gtgtggcagg cagcattaac acatgaattt gattatacca
    28201 agccactttc gggagtaact ttgcaaaagc aaccataaag gatgcaaagc cacaaagaac
    28261 agtagaaaca atgttatcac tcaaatacag tgctatgaaa acagataaac tcaaaaggct
    28321 aggagattat ttcctagcct tttgagcgtt taagactgcg tcaaatgtag ctgatttagc
    28381 ttgcacgcaa atgtcttctt gggttagagg gtttttcaaa cgtaattgat aagcatggag
    28441 catcagtcga gcacaatctt tttttccatt agaatacaaa ggatcaccaa ataaaacatg
    28501 accttgatgg gctaaatgga ctcgaatttg atgagtccgt ccagtttgta attgacaatt
    28561 gagtaagctt gccgttttgt ggaagttttt gactagagtt acctcagtaa tagctttctt
    28621 gccatttatc ggatcgacaa cacgttttct gcggtcatgt cgatgacgac caattggatg
    28681 atggtaagtt accctaggac tgtctaagga tccgtgaact agtgccaaat attctcgatg
    28741 gatatctcgt ttttctaaaa gacgattaag gattggtaag ataaaaggtg ttttagcaaa
    28801 taaaatggcc ccacttgttt ccttatccag acgatgaacc acatagcagg tctgtcccgt
    28861 gtaagcagac acgtggttga gcagcgccaa ctctgttgga tcattgccgt gtgttttcat
    28921 cccttcaggt ttgttaacaa taatgatgtg ctcatcttca taaaggcagg ttactttttc
    28981 ggcctgcccc atcacgataa tcttttcagg ataatcttcg tgatcaaaaa aaagtttgac
    29041 ctgatcaccg tatttaacac aactttgcca gttaacagga tgaccattaa taagaacatg
    29101 ttttttagtt ctcagaaaat gcctaatttt acggggaatt aacaattgtt cctctaataa
    29161 tgctttgacc gtcaattctt caaagggatt tttcagtgtg acagtaaacc cctttgatgg
    29221 tttatttgtt gtcttcattg agccagttat ggtatttttc aacaaggttg atagccattt
    29281 gggtggcaag agcagcagag aaagcttcag taccttcacg ctcgtcatta gctacctcca
    29341 agcgagtctc gtcgtaaatg gcttttagac tttctgcgga taaggtttct ttaaaagctt
    29401 ggaatttatt cattggttaa acccgtcctt ctatgtttaa tgtgagctcc tgattaatgc
    29461 aaggaattca atgctattat agcatgtttc taatcaaaac gtaccactca aaaaggtaaa
    29521 aacgttattt tgctaatcca tataataaga aagtgtctta aataagacct cttgatagag
    29581 tttgtaacaa aaatgatatg aaactaggtg ctaacgcaga aatagaaacc aactaacgtg
    29641 ttgcgaagtt ggaacagtca taaaaaatag caagataaaa cttatcaaca cacagttacc
    29701 taagacgatg aatcaaacag gtatgttctt tcaaaacaac cccatgaggt tgaacgacgt
    29761 atcggaaaaa tacggattag tttggcctta tgataggtat ttctctatcg taaaagaagt
    29821 caaccaaagg tttttaatat aaaatattaa gaaaaattgt tataattatg ataaaaacat
    29881 aatcgtaaaa tagaggaaaa acaatgaaaa caattagacg ttatgatgtt aacgaagata
    29941 gagggcatac aggccttgta gaagcaggag atttctatta tttaaactat tgtgtcggca
    30001 atgttggaca agacattgaa agtcagatta atggagcctt tgatgagatg gagcgccgat
    30061 tagcattggt ggggctcaca ttagatgcag ttgttcaaat ggattgtcta tttcgagacg
    30121 tttggaacat acctgtgatg gaaaaaatga ttaaagagcg ctttaatggc agatatcctg
    30181 ctcgaaaatc gattcaaacg gaatttgcac atcacggtgg accacaagga ctactctttc
    30241 aagtggatgg tgtggcttat tcaaagcata tttcgatgac ctaatcaagg ttactttaag
    30301 atcatagtgg tataataacg ttatgagatt tctagaactt ttacaaaaga aattttttcc
    30361 taaagcatat caggaaaaac aattcttaat gcatcaaaaa acgcgtttaa cgccacaaca
    30421 caatcaaaag cagtattcgc caaatgccaa tcatttggac tcatcagcta ccaaaaactc
    30481 agaacaagac cctgcaatag ctctgcaacg cagtagagcc tatgaaggaa gccctaaaag
    30541 tcggcccgct tggttgcaaa agctggaagc tgttttgccg tctcctcaac atccaattcg
    30601 gcgtttttgg cgccgctatc acatcggaaa actgctaatg attctgattg gaactcttgt
    30661 cttactctta ggatcatact tgttttactt atcaaaaaca gctaaagtat ctgatttaca
    30721 agatgccttg aaggctacaa ctgttattta tgatcacaaa ggagagtatg caggcagttt
    30781 atctggtcaa aaagggagtt atgttgagct caatgctatt tcagatgatc ttgagaatgc
    30841 tgttattgcc actgaggata ggacttttta cagtaatagc ggtattaatc ttaaacgctt
    30901 cttattggca gtagttacgg cgggccgctt tggaggtggc tcaacgatta cacagcaact
    30961 ggctaaaaat gcttatctct cacaagatca gacaattaaa cgaaaggcca gagagttttt
    31021 tttggcgtta gagttgacca aaaaatacag taaaaaagat attcttacta tgtaccttaa
    31081 caactcctat tttggaaatg gagtttgggg agttgaagat gccagtcaaa aatattttgg
    31141 aaccacagct gctaacttaa cattggatga agctgccaca ttagcaggta tgctcaaagg
    31201 acctgaaata tataaccctt accattctct aaaaaatgct actcaccgta gagatactgt
    31261 tttaggagcg atggttgatg ccaaaaagat tacccaaaca aaagctcaac aagctagagc
    31321 agtagggcta aaaaatcgct tagctgatac ttatgttggt aagacagatg actacaaata
    31381 cccatcctac tttgatgctg ttattagtga agcaatagca acttatggtc tttcagaaaa
    31441 agacattgtt aataatggat acaaagttta caccgagcta gatcaaaatt accaaactgg
    31501 catgcagacg acttttaaca acgatgaact atttcctgtt tcagcttatg acggtagctc
    31561 tgctcaagca gctagtgttg ctttagatcc taaaacagga ggtgttagag gtctgattgg
    31621 tcgtgtgaat agtagtgaaa atccgacttt cagaagtttt aactatgcga ctcaagcaaa
    31681 acgtagtccc gcatcaacaa tcaaaccact cgtggtttac gcgccagccg ttgcttcagg
    31741 atggtcaatt gaaaaagaac taccaaatac cgttcaagat ttcgatggct atcagccaca
    31801 taattatgga aattatgaat cagaagatgt tcctatgtat caagcattag caaactctta
    31861 taatattcca gcagtttcta cattgaacga tatcggaatc gataaagcct ttacctatgg
    31921 taaaacattt gggttagata tgagctctgc caaaaaagag ttgggggtag ctttaggtgg
    31981 cagcgtgaca accaatccat tggagatggc tcaggcatat gctgcctttg ccaataatgg
    32041 agtaatccat cctgcgcact tgattaaccg gattgaaaat gccaggggtg aagtgcttaa
    32101 aacctttact gataaggcta aacgtgttgt cagccagtct gttgcagata agatgacagc
    32161 catgatgcta ggtacctttt caaatggaac agcagtcaat gctaacgtat atggctatac
    32221 actagctggt aaaacaggga cgacagaaac caacttcaat cccgacttag caggcgatca
    32281 gtgggttatt ggttatacgc cagatgttgt tattagtcaa tgggtaggat ttaatcagac
    32341 cgatgaaaat cattatctaa cggattcaag tgcaggcacg gcttcagcta tttttagcac
    32401 tcaggcatct tacattttgc cttataccaa gggcagccaa tttcatgtag ataatgccta
    32461 cgctcaaaat ggtatttcag ctgtttatgg agtcaatgaa acaggtaatc aatcaggagt
    32521 tgacactcaa tctattattg atggtttaag aaaatcagca caagaagctt cgcaatcact
    32581 atcaaaagca gtcgatcagt cagggttacg tgataaagcc caatctattt ggaaagagat
    32641 tgttgactat tttagatagc ttgcagtatt ttagagatcg tgttaaaata atagttacgg
    32701 aggcgttatg gcacagaaaa aagcgagtct agcgtgtgtc gaatgtggca gtcgcaacta
    32761 ctctatcgga gtgagtagca cgcctaaacc aacacgtcta gaagtaaata aattttgcaa
    32821 atactgcaaa acatatacct tacacaaaga aacacgttaa aaaggagagc ctgatgggat
    32881 tcattagcgg gacttttaaa gtcttaaaag acacaacatg gccaaatcgt aaacaacgtt
    32941 ggaaagattt tatctcagtt cttgagtaca cagctttctt tacggtgatt atctacatct
    33001 ttgaccagct cttagcaaag agtgtattag cactgattaa tttattttag gtcaagattg
    33061 gtagaaatga taagcttgct tggaaaagcc taggctggga gtattcccag ccttttttgt
    33121 agtatcaata atctgattag taagcttttt taaagcccat actggtttga gctattcaaa
    33181 agcataaagg taaaggcaat gtagcaacga tctccaaacc aagttcacta aattggcttg
    33241 taacagagtc atcgcataaa cagcctggcc tcacttgctt agcacattaa aaatagcaat
    33301 gaatattatg gttgaggaaa acagcctgat agtctgctaa atcttcggga tgataggcct
    33361 tgacctcagc catctcatac tccctaccta gaagtttgta cttgttttct ccaaattgat
    33421 ggaaaggtaa cagttgcact tggtcaatct caagctgatt aaagagctct gagaaggctt
    33481 tagcatcgtc tagggaatca ttaaattggg gaataacagg gatgcgcaag acgatttctt
    33541 ttccagcttg aaaggcataa tgaatatttt tgataatcaa gtcattacga accccagtca
    33601 ctttttggtg tctgagctga ttataatgtt tcaaatcggt atagataaag tccacgtagt
    33661 caataagggt gacaaattgc tcgtgtttgg caaaggcggt ggtttcaatt gcggtgtgaa
    33721 gacctgctgc tttggctgct tttaacaggg ctaaggcaaa gtcaaactga gcaaagattt
    33781 ccccccctga cagggtcatg cccccacctg actcttcgta gaaatcaagg tctttaagga
    33841 cttcttcgat cacctcgtcc acggtttttt cctctccaac tattttagta ttaagcccat
    33901 cacttgttaa catctgctca ggcgcttttt gttgggattc gggattggca caccaaggac
    33961 atctcaaggg gcaacctttt aaaaaaacgg ttgtccgaat accagggccg tcatgaatac
    34021 taaaatgttg gatgttgaaa acaataccgc gatcagtcat aagtgtgaat tcctttcgtt
    34081 gtaaaaccat cataccagat aaacgtaaat aaatcaatta cgaatgaaag taaatatccc
    34141 ttttctttta agaaaataac tggtacaatg aaagagaggt gaatgatgaa tcgattagaa
    34201 cgtattattc aactggtttc ccagaagaaa aaaatagatg ttaacagttt atcagagcaa
    34261 ttagacgttt cgaaagtaac cattcgaaaa gaccttgata agcttgaaag taagggcttg
    34321 ttgcgacggg aacatggcta tgcggtgcta aacagtggcg atgacctcaa tgtacgcttg
    34381 tcctacaatt acaacataaa gcgacggatt gcagaaaaag cagctgaatt ggtgcaagac
    34441 aacgatacca ttatgattga atctggctca acctgtgccc ttttggcaga agtgctttgc
    34501 cagaccaaac gaaatattaa aatcattacc aattcgtgct tcattgccaa ctacattcgt
    34561 caatatagta gctgtcaaat cattttactg ggcggttatt accagcccaa ttcagaggtg
    34621 actgttggtc ctttattgaa agaaatgata tccctttttc atgtcaatcg tgtctttgtt
    34681 ggaacagacg gtttcaacaa agatcttggc tttatgggca aggacatgat gcgctcagaa
    34741 ggggtgcgtt acatggcaga tgctgctgag gaagtggtga ttctgaccga ttccagcaag
    34801 ttttcaaaaa ccagtctggt acaccagttg tcattagctg atgtcaatcg cgtcattaca
    34861 gaccaagcac tagacaagca aacacaagag ttattaagtg ctagtggtct tgttcttgat
    34921 tttgtttctt agaaaatagg tggctagatg aaagaagaac gcagacggct ccttgccaag
    34981 gtggcttact tgcattatgt tcaaggcaag agccaaacct tgatttcaaa ggaaatgaat
    35041 atctaccgaa caacggtttg tcggatgtta gcaaaagcca aggaagaagg cattgttcgg
    35101 attgaaattg ccgactatga tgctgattta tttgctttag aagaatacgt gcgacagcag
    35161 tatggcttgg aaaaactaga ccttgtgccc aaccaggttg aagatacccc aatggatacc
    35221 ttgacaaatg ttgctaaaac agcagctgag gtttttagac atgttgttaa agatggcgat
    35281 aagatcggtc tgtcctgggg agcgactctt tcttgcttga tggatgagtt aaatccaaaa
    35341 gcgatgaaag atgtgtttat ttatcctttg gcaggaggac ctagccatat taatgccaaa
    35401 taccatgtca ataccctggt ttaccgcttg gctcgcatct ttcatggtaa tagcgctttt
    35461 atgaacgcta tggtcattca agaagacaaa cacttggcta agggaatctt acaatctaaa
    35521 tactttaacg acattttaac aagctgggac cagttagatc ttgccttagt aggaattggt
    35581 ggggagccta atagccttga gcagagccaa tggcgtgatt tattaaccag ctcagatcat
    35641 gaccaactca aatatgaaaa agccgttggt gaagtttgtt gccgtttctt tgatcaggca
    35701 ggtcagccag tttacactgg cctacaggat cgaactattg gtatttcact agaacagttg
    35761 aggcgtgtcc ccaaaacaat ggctgttgca acaggtaaac acaaggctaa ggcaatattg
    35821 gcagccttaa aagcaggttt tatcaattat ctagtgacgg ataaagagac catgctagct
    35881 gttttagcgt tagatgaaga tattgatctt aataacgttc ttctttaata gaaattcaaa
    35941 aatactatga tatttataga ggcccaagac caaacggtca gggctttttt tgtttgatgt
    36001 gttgataaaa cagagattgc tcaaatgtgc agttaatgta ttggcacaaa agtgcattaa
    36061 ccaaaatata gcacaaaata tattgaccct aaaaacaaaa atgatacaat aaacttacca
    36121 acgaaatgta aacgattaca aacacaataa catcaccttc gaaaaaaaga ctcattgccg
    36181 ttacatcaca tgaaaaagaa aaaaaggaga caccaatgca agttattgta ccagaccaaa
    36241 tcattatggg cttaatttta aatgcaggcg atgccaaaca acatatctac caagctctga
    36301 aatgtgctaa agaggacgat tatgccacta gtgaaaaaga aatggcctta gcagatgatg
    36361 ccttattaga agcccacaat ttacagaccc agtttcttgc ccaagaagct agtggtaata
    36421 agtcagagat tacagctctt tttgttcact cacaggatca cttgatgacg accattacag
    36481 aaattaatct catcaaagag attattgacc ttcgtaaaga attggcaact aaataagttt
    36541 tcatgactaa aaaggagatt gacatgatta aaattggatt gttttgtgca gcaggatttt
    36601 caaccggtat gttggtgaac aacatgaaag tagctgctga aaaaaaaggc attgattgtc
    36661 agattgaagc ctatgctcaa gggaaattag cggactatgc accattactt gatgtggcac
    36721 ttttaggccc acaggttgcc tatactctgg ataaatcaga agctatttgt aaagacaatg
    36781 atatccctat tgcagttatc ccaatggctg attatggaat gttagacggc aacaaggtgc
    36841 ttgatttagc ccttagcctt gttaaagaat aggagtcaat catggcaaaa atgaatatgc
    36901 aaaacatcat caagccaatc atgacatttg tgaatatgcg cggcatcatt gccttaaaag
    36961 acggtatgtt agccatttta cctttgaccg ttgtggggag tcttttcctg attgctgggc
    37021 agattccttt ccaaggggtt aatgatgcca ttgctagtgt gtttggtgct gactggacag
    37081 aaccctttat gcaggtttac catggaacat ttgctattat ggggttgatt tcctgttttg
    37141 caattggcta ttcttatgct aaaaactcag atgttgaacc tctcccttca ggggttctat
    37201 ccttgtcagc cttctttatt ttattgagat catcttatgt tccagcagaa ggtgaagcta
    37261 ttggagatgc tatcagtaag gtttggtttg gtggtcaagg gattattggt gctattgtga
    37321 ttggtttaac ggtcggagct gtttacacaa catttatccg tcgtcatatc gtcattaaaa
    37381 tgccagatca agtgccacaa gccatcgcca aacagtttga agccatgatt ccagcctttg
    37441 tgatctttac cttgtcaatg cttgtgtata ttattgccaa gtcagtaaca ggtggtggca
    37501 cctttattga aatgatttat gatgtcattc aggtaccgct gcaagggtta acgggttctc
    37561 tttatggcgc actaggtatt gccttcttta tttcctttct ttggtggttt ggcgtgcatg
    37621 ggcaatctgt ggtcaatgga attgtcactg ctcttctctt atcaaatcta gatgccaata
    37681 aggccttgat ggcagcaggt gagttatcct tagacaaggg tgcccatatt gtaacccaac
    37741 aatttttaga ctctttcttg attctatcag gttctggcat tacctttggt ttagtggtag
    37801 ctatgatctt tgcggctaaa tccaaacaat acaaggcttt aggtaaggtt gcagccttcc
    37861 cagccctctt taatgttaat gaaccagttg tctttggttt tccaattgtg atgaatccag
    37921 tcatgttctt gccatttatc ttggttcctg tcttggcagc tctcacagtt tatggcgcca
    37981 ttgctattgg tttcatgcag ccctttgcag gagtgaccct tccgtggtca acaccggcca
    38041 ttgtctcagg gttcatggtt ggtggctggc aaggagctat tgtgcaaatt cttatactca
    38101 tcatgtcaac gttggtgtac ttcccattct ttaaaattca agataatatg gcttatcaaa
    38161 atgaacaagc tagtgaagag tcatgattta gcgtccacac aaattcttga gaccatctcc
    38221 agttagaggt ggttttttag aaaaagaaga gcgacttatc aggcctatat tgcacaatag
    38281 tgcaaaataa agtgactatc tcttcttatg gttaaggata cgcaaaagtc gcaatatatg
    38341 ataaaatagt tacgaaagaa acatttataa tttcgtaaga aagaaggaga ccccgcatga
    38401 ctgaaacaaa aagcccttat tttggacatt taacagacag aatgactcac tatcgtgaag
    38461 ctgtgttaga caagaaacct tatattgatg ctgagcgtgc tattttagcc actgaagcct
    38521 atcaaaaaca ccaaaataag ccagcaaacc tcaaacgcgc ttacatgctt caaactattt
    38581 tggaaaacat gaccatctat attgaggatg aaagcctcat tgctggtaac caagcctctt
    38641 cgaacaagga tgcgccgatt ttcccagaat acactctgga atttgccctc aacgaacttg
    38701 atctttttga aaaacgagat ggggatgtct tctacattac cgaagaaacc aagcaacagc
    38761 tccgagacat tgccccattc tgggaaaaca ataacttacg tgctcgctgc ggggtcttgc
    38821 taccagaaga agtgcaagtg tacatggaaa caggtttctt tggcatggaa ggcaagatga
    38881 actctgggga tgcccattta gcggttaatt accaaaaact cttggagcac ggcttaaagg
    38941 gatttgaaga acgggcacga gctgccaaag ctgcgcttga tttgaccatt cctgaaaaca
    39001 ttgacaaata ccatttttac gactctgttt ttattgtcat tgatgcagtc aaaacttatg
    39061 ccaaacgcta tgccaagttg gctagagaac tagcaaaaac ggctaaacca gaacgtcaag
    39121 cagaattgtt agacatcgcg cgtatttgtg acaaagtgcc ttacgaacca gcgaaaacct
    39181 ttgcagaagc tgtgcaatct gtctggttca ttcagtgtat cttgcaaatt gaatcaaacg
    39241 ggcattccct atcttatggc cgctttgacc agtacatgta tccttatgtc aaagctgatt
    39301 tggaggctgg ccgtgaaaca gaagactcaa tcgttgaacg tttgactaac ctctggatta
    39361 agaccttgac cattaacaaa gtgcggagcc aagcccacac cttctcatca gcaggtagtc
    39421 cactttacca aaacgtgacg atcggtggtc aaacacgcga taaaaaagat gcggtcaacc
    39481 cactgtctta ccttgtccta cggagtgtgg ctcaaaccaa attgccacaa cctaacttga
    39541 ctgttcgtta ccacaaaggc ctagacaata cctttatgaa cgagtgtatc gaggtcatga
    39601 aacttggttt tggcatgcca gccatgaaca acgatgaaat catcattcca tctttcatca
    39661 aaaaaggtgt ctcagaagaa gatgcttatg attactcagc cattggctgt gtggaaacag
    39721 cggttccagg caaatggggc taccgttgca cggggatgag ttacatcaac ttccctaaaa
    39781 tcttgctgat taccatgaat gacgggattg acccagcatc aggcaagcgc tttgcaaaag
    39841 gatacggtca cttcaaagac atgacctctt atgaagaatt aaaagcagca tgggatgcca
    39901 ccttgcgcga aattacccgc atgagcgtca ttgttgaaaa tgccattgac ctaggtcttg
    39961 aacgtgaagt gccagatatt ctttgctcag ccttgacaga tgattgtatc ggtcgtggca
    40021 agaccttaaa agaaggcgga gctgtttacg actatatctc aggccttcaa gttggaattg
    40081 ccaacctatc agactcccta gcagcgctga aaaaattagt gtttgaagaa ggccgcttga
    40141 ccccagaaga actctggcag gcccttgaaa gtgactttgc tggagaacgc ggagaagaaa
    40201 tccgccaaat gctcatcaat gacgcaccaa aatatggtaa cgatgatgac tacgcagata
    40261 gtttagttgt cgaagcttac gacacctaca ttgatgaaat tgccaaatac ccaaataccc
    40321 ggtatggccg tggcccaatc ggaggtatcc gctattctgg gacatcatca atctcagcca
    40381 atgtcggaca aggaaaagga accttagcga caccagacgg tcgccatgca ggcacaccac
    40441 tagcagaagg ctgttcacca gaacacagca tggacaaaaa aggacctact tcagtattga
    40501 aatctgttgc taaattacca acagatgaga ttgtcggagg agtactactc aaccaaaaag
    40561 ttaacccaca aaccctggcc aaagaagaag acaaactgaa attaatggcc ttacttcgta
    40621 ccttctttaa tcgcctacac ggttatcata tccagtacaa tgtcgtgtca cgtgaaacct
    40681 tgattgatgc ccaaaaacat cctgaaaagc accgcgacct cattgtccgt gttgccggct
    40741 actcagcttt cttcaatgtg ctctcaaaag caacccaaga tgacattatt gaacgtacag
    40801 aacacacact ttaggagaaa ataagtatgg aatacatgtt agacacttta gatttagaag
    40861 ctattaaaaa atggcatcac attttgcctc tcgcaggtgt gacctcaaac ccttctattg
    40921 ccaaaaaaga aggtgacatt gatttctttg aacggattcg agaagtccgt gctattattg
    40981 gtgacaaggc ttctattcat gttcaagtga tcgcccaaga ttacgaaggc atcttaaaag
    41041 atgctgctga aatccgcagg caatgtggag atagtgtgta tgtcaaagta cctgtaacca
    41101 cagaaggcct tgcagccatt aaaaccttga aagccgaagg ctatcatatc acagcaaccg
    41161 ctatttatac gaccttccaa gggttattag ccattgaagc tggcgctgat tatttggctc
    41221 cttactataa ccgtatggaa aatctcaaca ttgatccaga agctgtcata ggacaattag
    41281 cagaagctat taaccgtgag aatgctaata gtaagatttt ggcagcaagc tttaaaaatg
    41341 tggctcaggt caataaatcc tttgctctag gagcacaagc catcactgct ggcccagatg
    41401 tgtttgaagc aggatttgcc atgccatcta ttcaaaaagc ggttgacgat tttggcaagg
    41461 attgggaagc cattcatcac cgcaagagca tttaagaaat agcatcagta gtaatcacat
    41521 cattaggaat cacagataaa ggagttcaac gatgaaagta tttgcaagtc catctcgtta
    41581 cattcaaggt aaaaatgcct tgtttaccaa tgctaaaacc ctaaaacaac taggggatag
    41641 ccccatttta ctgtgtgatg acgtggtgta tggcatcgtc ggagaaagat ttgaaagcta
    41701 tttgatagat aatggcatga ctcctgttca cgtagccttt aatggcgaag cctcagataa
    41761 tgaaatcagc cgcgtggttg ccattgccaa ggaaaatggc aatgatgtta ttattggact
    41821 tggtggcgga aaaaccattg acagtgctaa ggctatcgct gacttacttg ctgttccggt
    41881 gattattgcc ccaaccattg cttcaacaga tgccccaacc tcagccttat cggttattta
    41941 caccgatgaa ggagcctttg aaaaatacat tttctattca aaaaatccag atcttgtttt
    42001 ggttgacaca caagtgatct gtcaggcacc aaaacgatta ctggcctctg ggattgcaga
    42061 tgggttagca acatgggtag aggcgcgtgc tgttatgcaa aaaaatggag acaccatggc
    42121 aggtggcaat caaaccttgg caggagttgc cattgccaaa gcctgtgagc agaccttgtt
    42181 tgcagatggc ctaaaagcga tggctagctg tgacagacaa gtcgtgaccc cggccttgga
    42241 aaatgtcatt gaagccaata cactccttag tgggcttggt tttgaaagtg cgggtctggc
    42301 tgctgcacat gccattcaca atggctttac agcgctgaca ggtgctattc atcaccttac
    42361 ccatggtgaa aaagtcgcct atggcacgtt gacccaactc ttcttggaaa atcgttcgcg
    42421 tgaagaaatt gaccgctaca tcgactttta ccaagctatt ggcatgccaa caaccctcaa
    42481 agaaatgcat ttagacacgg ctactcaaga ggatttctta aaaattggcc gtcaagcaac
    42541 catgacaggc gaaaccatcc atcaaatgcc atttgttatc agtccagaag atgtagcagc
    42601 ggctttggtt gctgttgatg cctatgttac gagtcgatag gctaaccaaa aagagatttc
    42661 ttatttgcca gataacctca aaaaaacaag tctagggagt cacttcctag atttgttttg
    42721 cttattgttg gttggtaata gcacttttag cggggtcatt gtgggcaata cggctggcag
    42781 ctgcagcagc aatggcgcta acaatatcat ctaaaaaggt atggcaggag tagccatctt
    42841 tatggttgag tttgtcaaca attcctggtt ttgtcttgtc cagataccca taattggtaa
    42901 aaccgataga cccatagagg ttaacaatgg ataaggccag gatttcatca atcccataca
    42961 gcccttggtc ggttttcaag atactaagga gtggctcaga cagctggttg gcttcagcca
    43021 atttatctaa ttctacccca gtgataatag cgttttgcac ttctcgtttt gcaagcaccg
    43081 cctcaacgct ctctaaacat tctgccatgg tcaaattggg aatataatca ttctgcaaaa
    43141 aaagcaccag ctctgcaata gcttctaaag aaccccctcg ctcagccagt aattgataag
    43201 acacttctcg taggtgatgg tcagttgaca tgtgagacct cctttttttc tttattgtaa
    43261 cataaaagat ttcgagaaac ctctacaaca gctaaagagg ggatagttct tttttaagag
    43321 atgttgacta ctgagatccc ctacttggta aaagtcaaag aaacgatagt aaagtaacca
    43381 tcttacctag gcctaaatac aatcaccacc cctaggtgac acacagcacc tatttcaaaa
    43441 atgatattag tatggcaaaa caaaaagaca acgccttctt ttttctcctt actatctcct
    43501 ttaattttca tattttttaa aaaaactatt gataaactag ttaagtaagc gtatactatg
    43561 gttagtgagc gaaattagaa aagaggacaa gcatatgaat ctacttggat caagacgggt
    43621 tttttctaaa aaatgtcggc tagtaaaatt ttcaatggta gctcttgtat cagccacaat
    43681 ggctgtaaca acagtcacac ttgaaaatac tgcactggca cgacaaacac aggtctcaaa
    43741 tgatgttgtt ctaaatgatg gcgcaagcaa gtacctaaac gaagcattag cttggacatt
    43801 caatgacagt cccaactatt acaaaacctt aggtactagt cagatcactc cagcactctt
    43861 tcctaaagca ggagatattc tctatagcaa attagatgag ttaggaagga cgcgtactgc
    43921 tagaggtaca ttgacttatg ccaatgttga aggtagctac ggtgttagac aatctttcgg
    43981 taaaaatcaa aaccccgcag gctggactgg aaaccctaat catgtcaaat ataaaattga
    44041 atggttaaat ggtctatctt atgtcggaga tttctggaat agaagtcatc tcattgcaga
    44101 tagtctcggt ggagatgcac tcagagtcaa tgccgttaca ggaacacgta cccaaaatgt
    44161 aggaggtcgt gaccaaaaag gcggcatgcg ctataccgaa caaagagctc aagaatggtt
    44221 agaagcaaat cgtgatggct atctttatta tgaagccgct ccaatctaca acgcagacga
    44281 gttgattcca agagctgtcg tggtatcaat gcaatcttct gataatacca tcaacgagaa
    44341 agtattagtt tacaacacag ctaatggcta caccattaac taccataacg gtacacctac
    44401 tcagaaataa taccaaaagg ctagacctct gctcactagg cctagctttt tacatcaaaa
    44461 aaagcaatga ctatagaaag taaaaatact agaaaaagca atgattgccg tcattgcttt
    44521 ttatgatttg tcaaaaagta aaaagcaaat tgaaaaaatc gccctggagc tgttgagata
    44581 aactacacca tttattaaga taccaaatca aaaagctaac accataagag cgttagcttt
    44641 ttaaagagcc tcaggacagt ttatgtttaa tggcttctag gtaggtttga aacatatgat
    44701 ggatcgtttt gcaattaagt aattggaaga tctccaagat ctgcacacac ttttgctcag
    44761 ccccctcttt accatttatg aggccaataa tgccatcaaa aaaagacaca caacaccgtt
    44821 catataagca atcatcattt agctgataat cttcaatttt tgccaaaatc tcagaagctt
    44881 tatcatactc ttgtcgctga ataaacaaaa tcaacatatt gacaaacatc cgaatcgatt
    44941 cattcccata ataccttagg gtattgtatt tatcgaggtt caaaataact tttgaaaaca
    45001 ccatctcaat aaagcaagac tcaaaaataa acatacaatt attaaaaagc acagtctcat
    45061 agtgactcca agtttcaata ttaataagat agtttgacaa ataagtccgc tctgtcagac
    45121 agtcttcctc agtaagagtt gctaataaca ccttgaccaa ggcaaaaagg ttcttttcct
    45181 ttgttgactt actatcttta taagaatcaa ggatatgatt taaaccttct atgtttcggc
    45241 attcaaaata atgttttgcc gtatccatat caataaattc tttgtattgt ttaaagttat
    45301 tactaataaa gagaaactca tcaacattga cattcaagtt gtctaagata taaagtaact
    45361 ttttcgaaga aatgtcaaga ttatttttaa taaaacgata ataggtttgc ttagtgagat
    45421 aatcaccaca aacttgttta atcgaaatgt tttttgaatg cctaatgaat tcaacggttt
    45481 caccaatttc catatgtcaa gccttcctag ttgatgtcaa aaatacgtta cgcatgtacc
    45541 taatacgtaa caagttgaat gtttcggatg atagtcgctt atgataggtg cataaggtca
    45601 atagccagat gcgatagttt tatcaactgt catatgttaa acctttctaa tctaatagat
    45661 gttaaaaata cgttacgtgt gtacctaata cgtaacaaaa taatgggtta gcaaaataag
    45721 cagctatgat atagccataa ggttaaaagg aggcgcctac tatgtggtta ttgttactat
    45781 ttttgtagtt ccttttgcaa aatggtagta gataaaaatg agaagtcaat aaaagcattg
    45841 acaaacaaaa gaatcatttt gtttatatta tcagtatttt taagtttctt gtcaactgaa
    45901 atgagcatct actagccaca atagtaacta aaaggctaat tgtcagtaaa aatgagataa
    45961 atcagccagg aaaaagccta cgagtcaact aatggacaac ccaaaaaaag acaaaggact
    46021 ttcacttggt gttgtggacc ctatcacgat ccttatcaca gaatcagtta ttaacaaaat
    46081 gagaacggtc ccatatcatc taaaaaaact gtcaagcaca acctattgtt tgctagctga
    46141 tcttgcctat cagtctgcct agtagatacg gcagaagata agagatcaac caaaagatga
    46201 taagtgcaac gactcatagc gtcttttgac caaaaccaat taggctcaca tgagatgaga
    46261 ataattgggt tgggttgtca gtgtcaacta accgtgttat tgtctattac cattcatggt
    46321 atcagcgaca tcgtatgata accatacgat tcagctaagt aaggaggtgt gtccaatgta
    46381 ccgttaaaag caaatgcagt agattaactt attttgaaag aggtataaaa aaaatgaata
    46441 aaaagaaatt aggtatcaga ttattaagtc ttttagcatt aggtggattt gttcttgcta
    46501 acccagtatt tgccgatcaa aactttgctc gtaacgaaaa agaagcaaaa gatagcgcta
    46561 tcacatttat ccaaaaatca gcagctatca aagcaggtgc acgaagcgca gaagatatta
    46621 agcttgacaa agttaaccta ggtggagaac tttctggctc taatatgtat gtttacaata
    46681 tttctactgg aggatttgtt atcgtttcag gagataaacg ttctccagaa attctaggat
    46741 actctaccag cggatcattt gacgctaacg gtaaagaaaa cattgcttcc ttcatggaaa
    46801 gttatgtcga acaaatcaaa gaaaacaaaa aattagacac tacttatgct ggtaccgctg
    46861 agattaaaca accagttgtt aaatctctcc ttgattcaaa aggcattcat tacaatcaag
    46921 gtaaccctta caacctattg acacctgtta ttgaaaaagt aaaaccaggt gaacaatctt
    46981 ttgtaggtca acatgcagct acaggatgtg ttgctactgc aactgctcaa attatgaaat
    47041 atcataatta ccctaacaaa gggttgaaag actacactta cacactaagc tcaaataacc
    47101 catatttcaa ccatcctaag aacttgtttg cagctatctc tactagacaa tacaactgga
    47161 acaacatcct acctacttat agcggaagag aatctaacgt tcaaaaaatg gcgatttcag
    47221 aattgatggc tgatgttggt atttcagtag acatggatta tggtccatct agtggttctg
    47281 caggtagctc tcgtgttcaa agagccttga aagaaaactt tggctacaac caatctgttc
    47341 accaaatcaa ccgtagcgac tttagcaaac aagattggga agcacaaatt gacaaagaat
    47401 tatctcaaaa ccaaccagta tactaccaag gcgtcggtaa agtaggcgga catgcctttg
    47461 ttatcgatgg tgctgacgga cgtaacttct accatgttaa ctggggttgg ggtggagtct
    47521 ctgacggctt cttccgtctt gacgcactaa acccttcagc tcttggtact ggtggcggcg
    47581 caggcggctt caacggttac caaagtgctg ttgtaggcat caaaccttag tatggaaatg
    47641 catttcgtta gaacagaacc tgaggcacgc cgcatagctg aaaccttttg tgctgaaaac
    47701 acacaaacaa aaacccctat gcgcgtgcag cagttaagct atccatcaga cacagatcac
    47761 tcaggtggtg agctatacat ctatgctttg tctcctgctg gatttatcat cgtatcagga
    47821 gacaccagag cgcacaccat tttaggctat tcttttgata ataacctaga cctcaaccat
    47881 gataatgtca ggagtatgat agaagcttac caaacacaaa tcagctcttt ggattgatcg
    47941 gtcaaagtag cttttgcccc ctcaccactc gtttaagacg accgtgtttc taaaatacca
    48001 ctacctttta agtttcacgc cggcctaagc gagtgtttgt ctcatggagc aaactgtttc
    48061 catcgaaaag tcacccattg ataaaggagg tcatcaacgc ctactaatga tgacttccct
    48121 aagatgccaa ggtaaaggac tgagttctgt agagatggga ctcagtcctt ttacgatttt
    48181 tgggagttat tctagccata ccgtggcaag aaaacaacac tcaaaaatag ccaacgtcag
    48241 tttctgttca tacatgacca cagccaaaca ccacaaccta acctaaccta tcctaaacac
    48301 agtggctttc taacgaacag tcacaacgag cagcaacacc aaaaagcaag attaagctac
    48361 gtttaagact aatgatataa gataacagta attattaatg agaaaagagg ctcaaaagga
    48421 catgaaacaa atgaataaac tcattacagg agtggtaacg ctggcgacag tcgtgacctt
    48481 atcagcttgt caatcatcac acaacaacac caaactcgtc tcgatgaaag gagacaccat
    48541 cactgtcagt gacttctaca atgagaccaa aaacacagaa ctcgcacaaa aagccatgtt
    48601 aagcttggtg attagccgcg tttttgagac acaatatgcc aacaaagtct ctgacaaaga
    48661 ggttgaaaaa gcctataaac aaaccgcaga ccaatacggt acatccttta agacagtcct
    48721 agcacaatca ggcttaacac cagaaaccta taaaaaacaa attcgcctca caaaattagt
    48781 cgaatatgcc gtcaaagaac aagccaaaaa cgaaaccatc tcaaaaaaag actaccgtca
    48841 ggcctatgac gcttataccc caaccatgac cgcagaaatc atgcagtttg aaaaagaaga
    48901 ggatgccaaa gcagcacttg aagccgtcaa agctgaaggg gcagactttg cagctattgc
    48961 caaagaaaaa accactgcag ccgataaaaa aacaacctac acgtttgact caggtgaaac
    49021 aaccctacca gcagaagtag ttagagctgc atcaggcctc aaagaaggga acagatcaga
    49081 aatcatcaca gcgcttgatc cagccacctc aaaacgcacc taccatatca tcaaagtcac
    49141 caaaaaagca actaaaaaag cagactggaa agcgtaccaa aaacgcttga aagacatcat
    49201 cgtgactggc aaattaaaag accctgactt ccaaaacaaa gtcatcgcta aagctcttga
    49261 taaagcaaat gtcaaaatca aagacaaagc atttgccaat atcttagccc agtttgcaaa
    49321 acctaaccaa aaacaacctg ccccaaaata gagggttgtc agtttatttc cctaaggttg
    49381 cttaaaaaga tagccctagc catcactccc cttttcaaaa caccgataat ggaaacgtgt
    49441 cctatactga tggtctaggg caatgtcata aagctaaaga ctctatccaa aaataaggat
    49501 agagtcttta atgttttaaa accagtcagc aaaaaaattc acgctaagcc tagctagaat
    49561 gaggcttagc gtgaatggta tcagtgatag tccgttaaac tagctgattg ggagtcagaa
    49621 actctcctta cccaatctga ctataccccc agtaccagag gtgtctcatc gcagaagtag
    49681 aaatcagata atcgtctgat aagctcttgt cctcaagcaa ctgatgagta tcgtcgcacg
    49741 ggccatgagc tgtcggtggc tgatagctag taggctcatc agccaaaact tttttggagt
    49801 aacgctttgg tctcagacgg cgccagaggg ttgagagagg ggtgagaaag aaacgatggg
    49861 tcatcttggc ctccttatct aatgatagtc accttaacag acaagagtgt caatactgtc
    49921 attttaagga gaaaaagatt aaaaatcaag gtcacaaact ttcctttgct gaaaaaacgc
    49981 gaccataata aagaacctaa atacccctcg tacttgatct tctctttgcg cagttatctt
    50041 gcgcactcag tttcctccaa gatagtgata gcgataccat tactgaccta taggctatcg
    50101 cggcaacccc ttttttcgcc tcaatgaggc tgatacagct gtcatgacag gaaaaagacc
    50161 tctgcctatc taagggatca ttaatttttt tctcaccaaa aaactgattt tagaaacgaa
    50221 aaagcatggt gtataataag gttcggaaca attatgacat aataatgaaa gtaaggttaa
    50281 cgaaacattg acaaattgta agtataaact tagaaagcta tctgtagggc tcgtctccgt
    50341 cggaacgatg ctgatagccc cgacagtttt aggacaggag gttagtgtta gtactgagac
    50401 gagtgctagt actagtacta gtaccgctag cgctggtacc agtacgagtg agacagctgc
    50461 cagcggaact gcgagtggaa ctaatggtgc gtcttccgta acatctagtg aaggaagtca
    50521 gagttcagaa tctgccccag cctcacctca acctcaagca cagacagctg tagctagttc
    50581 ttcgagctcg tctaatgcga atgcctcttc tagtagtgac gggaaagctc ctcaggcagc
    50641 aagcactacc tcatcttcaa ccccagcagc agccagtagt aatggtatca gtcaaggaac
    50701 tagtgctgaa gctgaaactc caatgatgga ggtggaacag tatacagttg gtaataaaac
    50761 aacagaacta aatattaaag acggtgctca gctaaaaaac gggagtaagg ttgataaaga
    50821 tacaaaactt atcagaaacc gtgatggtga gcagcgtgat attgttgata tcaagcgtga
    50881 ggtaaaaaca aacgcagatg gcactgtcga tgttacggtt accgtaacgc ctaaagaaat
    50941 tgacaaaggt gccgatgtta tggcccttct agatgtctct aaaaagatga cagaagatga
    51001 ttttaacaac gctaaggata agatcaagaa attagtcaca accttaacga gtaaatctcc
    51061 tgacagtcaa ccaaaccata atgctcgcaa ctctgtgcgc ctaatgacct tttaccgtaa
    51121 ggttaacgat ccgattgagc tcaacgcaga taatgtagac gctaaactag atgaggtttg
    51181 gaaaaaagct aaagaagatt gggactgggg cgttgattta cagggagcta ttcacaaagc
    51241 tcgagagatt tttaataaag gaaaaagaaa aaaatctggt aaacgccagc atatcgtctt
    51301 gttctctcaa ggtgagtcga cttttagtta tgacatcaac gacaaagatg aaaatgatac
    51361 tgtccagaaa aatagaatag ctggaaaagt tacgacctct aacccactat ttccctggct
    51421 acctatattt aatcatacaa atcaaaaagc agaagttatt gatgatgtag acaaattact
    51481 gggtttagct gaaaaaatgg gaatatcact gcccgatgga ttaagagcag gagtgaaggc
    51541 tattggggca ggtagtagtt tccttagtac cttcacagga tctggattga cagagtacct
    51601 cactttgaat gaatatcgct cagatatact aaaagaaaaa cagttcgatt ataccaagcg
    51661 tgtaggtgag ggctactact accacagtta ttcaaagcga actcatggag ataagatgcc
    51721 ctttgagaaa caaataagag aagttttaga gagattttta ccgaaaatcg aagataaaga
    51781 atggcctaaa aagtttatag aaatttttgg attacaagaa aaagaagtaa atcaaattgg
    51841 ggtagatgta attatgaaag taattaacag catcttctat aagcgtgaat accattacta
    51901 taatcacaat ctttcagcca ttgctgaagc caaaatggcg cagaaagagg gcattacctt
    51961 ttattccgtt gatgttactg actctgataa ggcttccaaa agggtaaagc gacaagttgg
    52021 aaatgagcag tctaaaaaga aaaaagaaga tgctgaaaaa gatcgaaaca ataagtttga
    52081 cgactatctg aaaaagatgt ctgaaggtgg taatttctta agtaaggttg aggagagagg
    52141 taagttcaaa gacactttaa cagagctaac gattaaagat gaatttacaa ataaggttaa
    52201 ggttcaggaa gattcagaag gtaaaaaata taaaaccggc ttaattagtg gaacatcaaa
    52261 tgtgacacat acccctgcta aaaccggatt tttctcatcc aatgaaagcc ttacttggac
    52321 catttccaaa gagcagttga aaaaagcctt tgaagatgga acgtctttaa ccctcaccta
    52381 taagcttaaa gttgagaacg acaagtttaa aaaatctctc gaggaagata ataagaagaa
    52441 gagagcaaaa cgttctgcac ctacagaaaa tgaaaactct gtcacagaaa aaatcatttc
    52501 aaatactact acctacaaaa ttaatgaaca aaaagttgaa ggtaacaaat ttgatgacgt
    52561 taatctgaca tacagtaaat tcaaggttcc tgtaccacag attgatggcc aagttattga
    52621 gccacaagca cctaaattac ctgacttacc tcctgttatt gagcatggcc ctgttcttga
    52681 ttacacagaa gaatcaatat accgattacc acttgaacat ggcagcaatg caccagacac
    52741 acaagtgaca attgaagaag acacagttcc tcaacgccca gatatccttg taggcggtca
    52801 gagtggaccg gttgacatca ccgaagatac ccaaccaggt atgtcaggct ca
//
LOCUS       DAUCXI010000009        49331 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.009, whole genome shotgun sequence.
ACCESSION   DAUCXI010000009 DAUCXI010000000
VERSION     DAUCXI010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49331
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.009"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            94..246
                     /locus_tag="VGY43_000529"
                     /pseudo
     CDS             94..246
                     /locus_tag="VGY43_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(293..823)
                     /locus_tag="VGY43_000530"
     CDS             complement(293..823)
                     /locus_tag="VGY43_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HEQ4301744.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(816..2150)
                     /locus_tag="VGY43_000531"
     CDS             complement(816..2150)
                     /locus_tag="VGY43_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HEQ4301745.1"
                     /translation="MKKYLNQNVYDALIERLHFLFNEFPIVYISFSGGKDSGLLLNIL
                     LDFRDKYYPDREIGVFHQDFEAQYSLTTKYVQETFTSLEGRKKVSLYWVCLPMATRTA
                     LSSYEMFWYPWDDKTEDIWVRPMPSQDYVINLENNSITTYRYKMNQEDLAKQFGRWYK
                     QIHGNQKTVCILGNRASESLHRYSGFINKKYGYQKECWITKQFKDVWTASPLYDWSVE
                     DIWHAYYKFSYSYNELYDLFYKAGLKPSQMRVASPFQDYAVDSLNLYRIIDQETWVKL
                     LGRVQGVNFSNIYGRTKAMGYKSIALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKS
                     IDFWHKTGGGLTEETINELIEKGYRIARNGISNYTSFKHSRVIFLDQIPDDTDDIVTT
                     KDVPSWKRMCFCILKNDHICRTMGFGLTREQQKIVAFLKEKYKTSLKELESE"
     gene            complement(2826..3293)
                     /gene="perR"
                     /locus_tag="VGY43_000532"
     CDS             complement(2826..3293)
                     /gene="perR"
                     /locus_tag="VGY43_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEQ4301746.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQPDF"
     gene            complement(3345..3800)
                     /locus_tag="VGY43_000533"
     CDS             complement(3345..3800)
                     /locus_tag="VGY43_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEQ4301747.1"
                     /translation="MIYSFQNPSEDVLKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEAQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNH"
     gene            complement(3987..6629)
                     /gene="polA"
                     /locus_tag="VGY43_000534"
     CDS             complement(3987..6629)
                     /gene="polA"
                     /locus_tag="VGY43_000534"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEQ4301748.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK
                     GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKASKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAAISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     REAIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQAKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            complement(6760..8487)
                     /locus_tag="VGY43_000535"
     CDS             complement(6760..8487)
                     /locus_tag="VGY43_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEQ4301749.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGMFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAIFLIAALGRGIMTMASGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAKKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIDKFHWTQKDMAAVMLDINKGMSPEAAAKKWVEAN
                     KSKVSSWTK"
     gene            complement(8503..9699)
                     /locus_tag="VGY43_000536"
     CDS             complement(8503..9699)
                     /locus_tag="VGY43_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ4301750.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVRKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            complement(10187..11278)
                     /gene="ulaG"
                     /locus_tag="VGY43_000537"
     CDS             complement(10187..11278)
                     /gene="ulaG"
                     /locus_tag="VGY43_000537"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEQ4301751.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSLEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(11531..13177)
                     /locus_tag="VGY43_000538"
     CDS             complement(11531..13177)
                     /locus_tag="VGY43_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEQ4301752.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INQALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            complement(13502..14206)
                     /locus_tag="VGY43_000539"
     CDS             complement(13502..14206)
                     /locus_tag="VGY43_000539"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEQ4301753.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKAEVDGAYEQETGSVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVAKMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            complement(14208..15071)
                     /locus_tag="VGY43_000540"
     CDS             complement(14208..15071)
                     /locus_tag="VGY43_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEQ4301754.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDPAIEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLA"
     gene            complement(15076..15738)
                     /locus_tag="VGY43_000541"
     CDS             complement(15076..15738)
                     /locus_tag="VGY43_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEQ4301755.1"
                     /translation="MTHLPNLQVALDHSDLQGAIKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     MKEERGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIRRI
                     WG"
     gene            complement(15847..16332)
                     /locus_tag="VGY43_000542"
     CDS             complement(15847..16332)
                     /locus_tag="VGY43_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ4301756.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVQLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALITLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKNSPYLEGLDLD
                     S"
     gene            complement(16455..16733)
                     /locus_tag="VGY43_000543"
     CDS             complement(16455..16733)
                     /locus_tag="VGY43_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ4301757.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            complement(16804..18237)
                     /locus_tag="VGY43_000544"
     CDS             complement(16804..18237)
                     /locus_tag="VGY43_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ4301758.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGIIQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            complement(18544..21045)
                     /locus_tag="VGY43_000545"
     CDS             complement(18544..21045)
                     /locus_tag="VGY43_000545"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEQ4301759.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQ
                     AEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGNEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSGFLDHLDKASA
                     IAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK"
     gene            complement(21256..22395)
                     /locus_tag="VGY43_000546"
     CDS             complement(21256..22395)
                     /locus_tag="VGY43_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEQ4301760.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELVQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHPNHDTHLQQAKNGGAVLSFELASKEELMTFTHRIQLPILAVSLGGVESILSHP
                     ATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF"
     gene            22880..23161
                     /locus_tag="VGY43_000547"
     CDS             22880..23161
                     /locus_tag="VGY43_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301761.1"
                     /translation="MKNKLFLVALATVTVLGPSLATPHHQTVHAAEQALAGTCTYSNE
                     NPYVGVCFERKDGMPIEENIITKNNDFSLLNWFWEIVTNWWSKITGYFS"
     gene            23346..23513
                     /locus_tag="VGY43_000548"
     CDS             23346..23513
                     /locus_tag="VGY43_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301762.1"
                     /translation="MKKKLSLFMIATAAVAGLSLATLGEHQTVSANDANYSNGFYGHN
                     GPESWLLYTVW"
     gene            23925..24155
                     /locus_tag="VGY43_000549"
     CDS             23925..24155
                     /locus_tag="VGY43_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301763.1"
                     /translation="MKKKLSLFMIATAAVVGLSLATPENQTVSANEAVATQACNYDFY
                     GYCGPISWLFYKTKHLLMGEQPTTTSTATVTK"
     gene            complement(24436..24822)
                     /locus_tag="VGY43_000550"
     CDS             complement(24436..24822)
                     /locus_tag="VGY43_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301764.1"
                     /translation="MKQQSYQPLRFVYLLVALFAAMLLVARPVMADEEQTPEDRAYSQ
                     GLEKGTEAGRKAGEEATWTDLTPTVPTDLETPDDIEDTNKQLYKEGYTDGYKEGYNEG
                     FGEHYPLLIPVQFIWGIILHWWEMLS"
     gene            complement(25076..26791)
                     /gene="slo"
                     /locus_tag="VGY43_000551"
     CDS             complement(25076..26791)
                     /gene="slo"
                     /locus_tag="VGY43_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HEQ4301765.1"
                     /translation="MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETT
                     TTNEQPKAESSELTIEKADQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDMTYPAALQLADKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKDLQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRT
                     EYVETTSTEYTSGKINLSHQGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            complement(26815..27300)
                     /locus_tag="VGY43_000552"
     CDS             complement(26815..27300)
                     /locus_tag="VGY43_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HEQ4301766.1"
                     /translation="MYKVPKGLEHYQKMFQKEVTVNDFKKYLIGSDKEYRITRRDSYM
                     GDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSILANITKALKDAHIREAMAHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            complement(27305..28660)
                     /gene="nga"
                     /locus_tag="VGY43_000553"
     CDS             complement(27305..28660)
                     /gene="nga"
                     /locus_tag="VGY43_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HEQ4301767.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENK
                     KSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTVWEENSPGGGVGEVLSYKFASPM
                     RIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNMERDLFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAVQMSAVASRAEYYRMYVSRKYQYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     RYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDR
                     K"
     gene            complement(29032..29571)
                     /gene="nusG"
                     /locus_tag="VGY43_000554"
     CDS             complement(29032..29571)
                     /gene="nusG"
                     /locus_tag="VGY43_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEQ4301768.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            complement(29744..30787)
                     /locus_tag="VGY43_000555"
     CDS             complement(29744..30787)
                     /locus_tag="VGY43_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ4301769.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSAKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVVKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYVEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIETAK
                     KAIIEGTITVPEN"
     gene            complement(31114..32406)
                     /locus_tag="VGY43_000556"
     CDS             complement(31114..32406)
                     /locus_tag="VGY43_000556"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEQ4301770.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            32844..33722
                     /locus_tag="VGY43_000557"
     CDS             32844..33722
                     /locus_tag="VGY43_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301771.1"
                     /translation="MIRKYDRTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKVAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPKIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHEANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDEDLDETLRRLNESDLKDFDISLR
                     IMQGATQRRTTHHQKD"
     gene            33735..34997
                     /locus_tag="VGY43_000558"
     CDS             33735..34997
                     /locus_tag="VGY43_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEQ4301772.1"
                     /translation="MADFNFDIDQIADNAVVKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITAKAPALVDTFLADQNALLDFGQSAVEGVNATVNHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDNM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSTTPDYQIKADLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPA
                     LEQSAQSPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKTTHA"
     gene            complement(35117..35743)
                     /locus_tag="VGY43_000559"
     CDS             complement(35117..35743)
                     /locus_tag="VGY43_000559"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEQ4301773.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDL
                     IRENNELRQTLEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLEETIHYIELKLEEAERASLVRIMKITS"
     gene            complement(35788..37203)
                     /locus_tag="VGY43_000560"
     CDS             complement(35788..37203)
                     /locus_tag="VGY43_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEQ4301774.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            complement(37204..38979)
                     /locus_tag="VGY43_000561"
     CDS             complement(37204..38979)
                     /locus_tag="VGY43_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEQ4301775.1"
                     /translation="MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRR
                     DQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDF
                     LIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLV
                     AIHTGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQ
                     QSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFD
                     SVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFNEIMEGTAQVRDRIARSKFIPEE
                     NLEQIKGLTQKVTKEIHHVLAKGGI"
     gene            complement(39180..39500)
                     /locus_tag="VGY43_000562"
     CDS             complement(39180..39500)
                     /locus_tag="VGY43_000562"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEQ4301776.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEALTHYDNQVLPAVLPLPTHQGAQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            complement(39497..40495)
                     /locus_tag="VGY43_000563"
     CDS             complement(39497..40495)
                     /locus_tag="VGY43_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEQ4301777.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKERVIERMRPIA"
     gene            complement(40511..41095)
                     /locus_tag="VGY43_000564"
     CDS             complement(40511..41095)
                     /locus_tag="VGY43_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEQ4301778.1"
                     /translation="MNDITQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKALEQQFQVAQQQLKNQERQALLALKQDSIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            complement(41164..41643)
                     /locus_tag="VGY43_000565"
     CDS             complement(41164..41643)
                     /locus_tag="VGY43_000565"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEQ4301779.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            complement(41645..43645)
                     /locus_tag="VGY43_000566"
     CDS             complement(41645..43645)
                     /locus_tag="VGY43_000566"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEQ4301780.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPPIGKLTA
                     LRQKTPSLSFKQFEESHRQQAAQTTLKMMSQKIERLEQLQNKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANDHFYHQLKQYKGLFIEEVYHTEFEYGLVLFWQ
                     AQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQSQKILAQL
                     QVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEVDSVNQLKGLMTETLGDMFYLDSY
                     DVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTFFGMMVAD
                     LGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVALWGLIYGSFFGFDLPVALL
                     STKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFILLGLLLF
                     ILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGISSYLSDL
                     VSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLSMLSGYVH
                     GARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            complement(43635..43955)
                     /locus_tag="VGY43_000567"
     CDS             complement(43635..43955)
                     /locus_tag="VGY43_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301781.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            complement(44410..45429)
                     /locus_tag="VGY43_000568"
     CDS             complement(44410..45429)
                     /locus_tag="VGY43_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEQ4301782.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGGACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            complement(45466..45831)
                     /locus_tag="VGY43_000569"
     CDS             complement(45466..45831)
                     /locus_tag="VGY43_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEQ4301783.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            46005..46685
                     /locus_tag="VGY43_000570"
     CDS             46005..46685
                     /locus_tag="VGY43_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ4301784.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            complement(46806..47453)
                     /locus_tag="VGY43_000571"
     CDS             complement(46806..47453)
                     /locus_tag="VGY43_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEQ4301785.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGAAFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGVFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(47456..48115)
                     /locus_tag="VGY43_000572"
     CDS             complement(47456..48115)
                     /locus_tag="VGY43_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEQ4301786.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLILICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            complement(48127..49311)
                     /locus_tag="VGY43_000573"
     CDS             complement(48127..49311)
                     /locus_tag="VGY43_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEQ4301787.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLVDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELGLPILA
                     KITSYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
BASE COUNT        14744 a        10660 c         8907 g        15020 t
ORIGIN      
        1 ggtatgaagt ccccttatac acatactttc aaaacagctc tcaatcctct gtccgctaca
       61 aaaatacgtc accgctgccc tccggctgct tcattcaacg acaaacttga agccacaaac
      121 agactcatca agggcattaa gtacaatgcc tttagatttc agaactttga caactttaaa
      181 accaaaatcc tcatcgcttt gaacatccaa aaagagagaa ccaatctgat tctctctcgt
      241 tgttaatgat aagtcaccca ctacagttga caatgagtct cttacttcct gtttactcat
      301 ttaatagctc ttctggttcc caagattgat taaactcatg gtccttaaaa agagaagcca
      361 atcctgttat ttgtttcagt cttaaaattt catctttatc cattcctaaa tgttttgcaa
      421 tccagttatc acttcgccca cactcatgaa gatcctttac aatctgactc atcaaatcaa
      481 catcatgact tcctctagct ctattatgtc gaatggtaga agccattcga tagtctaatg
      541 acttatcaat aacagaaaca ggtaatctcc cactttccct ttcataaata tctgaataat
      601 ctagcattat acgatatcta tgaaaaccat caacaatact ataccgatcc tcttccttat
      661 cgtaatagca aacaatcggc atagtataac catcagattt tatactatca tacaataatt
      721 tcatttcagg cggagcaact gaattcggat tataatcatt tggagaaatc ttttcaattg
      781 gaattgattt aatctcatag actggactaa taaaattact cactttctaa ctcctttaaa
      841 ctcgtcttat atttctcttt taaaaaggct actatttttt gttgctctct tgtcaaacca
      901 aaccccatag ttcgacaaat atgatcattt tttaaaatac agaaacacat tcgtttccag
      961 cttggtacat cctttgttgt tacaatatcg tctgtatcat caggaatttg atctaaaaaa
     1021 ataacccttg aatgtttaaa agaggtataa tttgaaatac catttctagc aatacgatat
     1081 cctttttcaa ttagttcatt aattgtttcc tccgtaagtc ctccgcctgt tttatgccaa
     1141 aagtctattg atttattaaa ttttctaaca taattatttc ttaacctcac tggtagcgtt
     1201 gataaaagaa actgagtata cgacttccac gaatgaccct ttggtaaagc aattgattta
     1261 tatcccattg ctttagtacg tccataaata ttcgaaaagt taactccttg aacacgtccc
     1321 aaaagcttta cccaagtttc ttgatctatt attctataaa gatttaggct atcaacagca
     1381 tagtcttgaa aaggagatgc aactctcatt tgtgatggtt ttaaacccgc tttatagaat
     1441 agatcataaa gttcgttata agaataagaa aacttatagt aagcatgcca tatgtcttcc
     1501 actgaccaat catataaggg agatgctgtc cagacatctt tgaattgttt ggtaatccag
     1561 cattcctttt gataaccata ctttttattg ataaaaccac tatatctgtg taaggattct
     1621 gaagcacggt ttcctaatat acaaactgtt ttttgatttc cgtgaatttg tttataccac
     1681 ctaccaaatt gtttcgctaa atcctcctga ttcattttat aacgataagt agtaattgaa
     1741 ttattttcca aattaataac ataatcttga gatggcattg gtcttaccca gatatcttct
     1801 gttttgtcat cccacggata ccaaaacatt tcataactac taagtgcagt tctagtagcc
     1861 atcggtaagc acacccaata caaagaaact ttttttctac cttctaaaga agtgaatgtt
     1921 tcttgaacat attttgttgt taaactgtac tgtgcttcaa aatcttgatg aaacacacct
     1981 atttctctat ccggataata tttatctcta aaatccagta aaatattaag aagtaaccca
     2041 ctatcttttc cacctgagaa ggaaatatag acaataggaa attcattaaa caaaaaatgt
     2101 aatctttcta tcaatgcatc ataaacattt tgatttaaat actttttcac taaacttcct
     2161 cattatgcat ttaaaaatat taatacatag attcactaag aatctctttt tcgatctttt
     2221 tgttttttaa tttttcaagt tgaataatta aaccttgctt ttctttttca aggtaataga
     2281 ctctactcct tgtaagtcta acttattctt aatcttattt atcgctcatt ttttaaattc
     2341 cgatgctctc acagatatta tcattgttta gttacatgtc tgtcaatcta ttcgccacca
     2401 cactaggggc catctgattg aaaaataaaa tttcggagtc cgttgtttgc tcaagaatca
     2461 tatctgtcac aattacgtca tactctgaag acagtgaacc atatcaacca tggtcagcct
     2521 caagtcatca aagttgacaa tctcaaaaaa tcctccaaaa tactctttta agaagttgcc
     2581 aacattgtta taacttctct caaccactaa tagtttcaag cgacgacgcg attgatttgt
     2641 aagaaagaga ttttcccagg tgaggaacaa acaatagagg agatgattga tggttctttc
     2701 ctttaattcc ttatgatccc cagcaaataa ctctttaaca taagcaacaa aggtctgata
     2761 gtgaactggg ggtttttgat ttgtaaaggc actatattta taatgccttt atttaagggt
     2821 taactctaaa aatcaggttg atcttttgct tggcaatccg gacaaatccc gtaagcaata
     2881 actgggatac gcgtgacctt ataacctgtt tgctcatggg cttctttggc aatatccata
     2941 acatcaacat ccataaagtc agcaatcttc ccacatattt cacaaaccac attgacgtgt
     3001 tgatggccca taaagtcata gtaggtggtt aaatcattgc tgattttcaa ctctgagaca
     3061 aaaccttcat caactaaaac tttcaaatta ttatagactg tggcaaggct catgttagga
     3121 aagttaggct gtaagtcacg gtaaatctta tcggcactag ggtgttctgt ggactgaatc
     3181 atgtaagaaa taatggcttt acgtgtctct gtaattcgaa tatgtttttc ccgtagatgc
     3241 tctaggacat tttcataggc atctagggct tgctgatgtg aatgaatgtc cataagctgc
     3301 tactcctatc cttttttcct ttattatcac gcacgtctct agtttcaatg attcgtgatg
     3361 cattctggtt tagcgactaa ttgcaaatag tctattttta ggcagcggtt catcacaata
     3421 gcctctttgc ctgccgaccg taaaatggtt tgtgcttctt ggttttcaag gcctaattgc
     3481 gcccaaaaga ctttggcctg acctgctaaa aagtctctgg caacttctgg taaaaactca
     3541 cttctgcgaa agacatctac aatgtcaacc tcaaagggaa ttgccttgat actggcatag
     3601 accttctctc ccaaaataag ctgacctgct aatttgggat tgactggaat gatccgataa
     3661 tccatagcct gcataaattt ggcgacacca taagctgctg tgtctttgcg gtcagaaaga
     3721 ccaacaaccg caatggtttt ggctgactcc aagtaagctt ttaggacatc ctctgaggga
     3781 ttttgaaacg aataaatcac ttgttcccct atctatttaa taacctctac agctgttcaa
     3841 tatagcagga taactcctaa agcatggctt caatcacttt taaccttatc cgtcaaaaag
     3901 ctcaaagcag cttcatgact tctcctacaa ttttttagtt tattataaca taagttgtca
     3961 aaatgagaaa taacaagtaa gaaaacttat ttggcttcgt accagctctg cccagtactt
     4021 tcatcgacac ataaaggaac agctaaatca acagcagctt ccatggtgtc tttgacaagt
     4081 ttttttatag cagtcaactc atcatttggc acttccaaaa cgatttcatc atgcacttga
     4141 agcagcattt tagctctaaa accacctgct tgcaaggcct tatccagatt aatcatagca
     4201 atttttagaa tatcagctgc gcttccttga atgggcgagt tgatagctgt acgctccgca
     4261 aaagagcgaa cgttgaaatt acgagagttg atatccggta attcacgacg acgcttaaag
     4321 agggtctcta catagccctt gtctttagcc tcacgcacca cattttccat ataggcttta
     4381 atcccaggat agcgttcaaa ataggtatca atgtaagact tggcctgttt acgggtgata
     4441 ccaaggttat ttgacaaacc aaaatcagaa atcccataca caattccaaa gttaacagcc
     4501 ttggcattac ggcggtcatt ggcagtaaca tctgctgcct tgtcaatccc aaacacacgc
     4561 atagccgttg aggtatgaat gtctgcccct tcattaaagg cagcaatcaa atgctcatcc
     4621 cctgaaatat gtgccagtac ccgcaattca atctgtgagt aatctgaact caacaagacg
     4681 gcatcttcat gagatggggt aaaggcctta cgaatcaaac gcccctgttc caaacgaata
     4741 ggaatgtttt gaagattagg gtccacacta gacaaacgcc ctgtctgggt gagatcctgc
     4801 acatagcggg tatgaatctt gccatcagcc agaatataat cctgtaaacc aatcacataa
     4861 gtggattgca atttagtaat ctggcggtaa tccaaaattt tagccacaat tggagcaatc
     4921 ggtgccaaac gttccaaaac atccactgct gtagaataac ctgttttggt cttcttagtc
     4981 atctcaagag gtagttgcat cttctcaaac aagatactgc ccagctgttt aggcgaatta
     5041 atgttaaatt cttggccagc catatcataa atctcttggg tgagcgcttc aataatgacc
     5101 ttgttttgct ctgccatatc ttgcaaagtc gccctattaa ccttgatccc ttcaatttcc
     5161 attttagcaa ggacattagc caaaggcaat tcaatattct gatagaggtc tagttgctca
     5221 tgggcagtga gcttgtctag catttgagac ttgctatcta ataatacttt gaccttacga
     5281 gctaagtgtt ctaataagac gtctttatca ggaacagccc gtttagcacc tttaccatag
     5341 actgtatcgt cttcttccaa agagatgtca gtaaaaatgc gggcaatggt gctaagctca
     5401 ttgtcttcta cagttgacag aaggtaatta gctaatctag catcatagct aggtgctacc
     5461 aactcaattc ctaagtggct caacaaaacc ttgctacgtt taaaatcata agtggcaatg
     5521 ggtttttgga agacctgctt aaaactatcc gtcgctaata ggctaaggtc agtggatgcg
     5581 taaatctgct caccatgtcc ccaagcaaaa ccaatgatgg cctcacgatg gtaattgtcc
     5641 cgaagcgttt caaagtagaa gatgtcttct gcgctaaaca aatcagcaga cacattggtc
     5701 acttcttgat aggaaatggc agctactggc tcttgaggca tctggctagc aagacctttc
     5761 ttgagttgca caaaatccat ctcatcgtaa aattgagaga ggctagcaac atctggacca
     5821 ttgtagacga tatcatctaa gccaattgtg ataggagatg ctgtattgat agtggcgagc
     5881 gttttagata ggaaagcttg gtcacggtca ttaatcaagt tttctttcat ttttgaggcc
     5941 ttgaatccat caatatgctc gtaaatgcct tccaaactac caaattcatg aaggagctta
     6001 aggcctgttt tttctccaat ttttgtcact ccaggaatgt tatccgattt atctcccatc
     6061 aaggctttga ggtcaataaa ctggtttggc gtcaagccca ttttttccat gaggtaagcc
     6121 ggtgtgaatt cttcaaattc ggcaacccct tttttagaaa tttcaaccac ggtattttcg
     6181 tcagttaact ggatcaaatc tttatcacca ctgacaatgg tcacatcaaa aggcacttct
     6241 gtgcgctccg ccattttatc aagcgtcccg ataatatcgt ctgcttcgta gtgttccaac
     6301 tcataataag caatcccaag ggctgtcaac atctcacgaa tataaggaaa ctgctcacga
     6361 aattcatctg gggttttagc tcgacccgcc ttataatcgg catacatttc tgttcggaag
     6421 gtggttttgc ccgcatcaaa agccaccagc acgtgagtag gctggactct tttcatcatg
     6481 tggtctagca tcagatgaaa gccataaatg gcattggtat gaagaccgct atggttttta
     6541 aagcggtcaa tttgattgta aagggcaaaa aaggcacgaa aggcaacaga tgacccatca
     6601 attaatagta atttattctt gttttccata agcttattat aacacagagg gacgggcttt
     6661 tctcctttaa gccattggtt ttgctgataa gtaaatggtt aacctaaaaa gcctaggaaa
     6721 attcctagac ttctctattt gctatttaga caaaagcact cattttgtcc aacttgatac
     6781 tttagatttg tttgcctcta cccatttttt ggcggcagct tctggactca tgcctttatt
     6841 gatgtcaagc atgactgctg ccatatcttt ttgggtccag tggaacttat caatgatttt
     6901 gtagacattt ggaagatctt ttttcaagcc tttacgagca atggtattga tgttctcagt
     6961 cgagccaaag gtttctttag gatctttaag gtacttcaag tcatacttgg caaacatcca
     7021 gtgtggtgac caagctgtca cgacaatagg atcttttttc ttgatcgctt gatccaagga
     7081 agtcgtcatg gctcctgttg atgccgccac taactcccaa ctagatagat tatgatactc
     7141 ttttagagtc tttttggctg ctgccatgat acctgcacct ggttcgatcc ctgtgatttt
     7201 ttgatcggct tgtttgctta agtcctcaat actattgaca tctgtcatgt attttggaac
     7261 agctaaacca agtttggtcc cttttaggtt aggtcctaaa tcatctaatt ttgacttgta
     7321 tttctgatat tgttggccat gggtgactgg caaccaagca ctagttgaaa agtcagcgtt
     7381 gccattagca acggtttgcc acatgacagc attgtcaagc ggagtcaagg tcacatggta
     7441 accttcgttt ttcaaaactt ctgcaatcac atgagttgag gcaacctcag aatcccactg
     7501 cacgtaagcg atgttaacag tttcaccctt atctgccata cccgaagcca tagtcataat
     7561 accacgtcct aaagcagcta tcaaaaagat agcaagggct gctagaccaa tccatttatt
     7621 ggttttgcca gctttggctt tttcttgagg tttactattg aacaactgtg tcatacggtc
     7681 aagcacaatc gccaagataa ccaaggcaag accactgaca aatccactac caatatcagc
     7741 gtgttgaagg gctgacaaga cttcacgtcc taaaccagga gcaccaatca tggagcctgt
     7801 tactaccatg gaaagggcta acatcatggt ctgattaaca cctgccataa tagtattttt
     7861 agctaaaggc aattcaactt taaagagctt ttgtttccca gttgacccaa aggcatctga
     7921 ggcctcaatc aattctgttg gaatgtcacg aatggccaaa tttgtaaaac gaactgttgg
     7981 gggcaaggca aagatgactg aagcaaatac tccaggcacc ataccaatac caaaaaaggc
     8041 aacggcagga atcaagtaaa caaaagccgg catggtttgc ataaagtcca aaataggatt
     8101 cacaatctga cggacagtgg catttttagc catccaaatc cccagcggaa taccaataag
     8161 taccgaaatc aaactagcta ctaacaccag agtaaaggta ttcattagct gcttccataa
     8221 cccttgattg taaataaaga gcaatcctaa caaggtaaag gttggcaaag gccatttttt
     8281 cttagcaagg aaaaacatcc ctgctgttac tagaacaata aaaagtaacg ggtggataaa
     8341 taaaagtgtt ttggtcatcc aatccatcaa aaagctacca actacttgca taatatcaaa
     8401 tagacctgag aaagttttag ttagccactc cgttagctgc tccaccagtt gagctactgg
     8461 taattttgtt tgtaatatcg tttccaaaat gcatcactcc ttttagttaa ggtcttcgtc
     8521 tgagatatta gccaaggctt caatcactcg tcctcgaata atgacaccta acagacgatt
     8581 attatcatct gtcactgcaa tcggagcaga tgaatcatag ataagaggca aaatatctgt
     8641 aataatagta tcttttgaga cagttctcac atcgcgatca atcacttctg atagcggtaa
     8701 cccttttttg cgcgcctcta tagcggcatc ggccgtcaaa ctaccgacta attggcggcg
     8761 gcgattcgtc gccatcaaca tagacacctc ttcgttgtgc atacggttca aggcaacttg
     8821 aggtccatct aattcaacag tagttgttaa cggtttgatc atgatatttt gtgctgtcaa
     8881 gactttagaa cggtccacat cctcaacgaa ttcacgcaca aagtcattgg ctgggttagt
     8941 caagatttcc tcaccagtac caatttgcat aatttgtccg tctttcatca aagcaatccg
     9001 atcaccaata cgcaaagctt cattcaagtc atgactgata aagatgatgg tttgtttcat
     9061 gctatcttgc aaatcaagta attcatcttg catctcacga cgaatcaaag gatcaagcgc
     9121 tgagaatgcc tcatccatta agagaatttt aggactatta gctagcgcac gggctaggcc
     9181 gacacgctgc tgcatcccac cagatagttg gtttgggtac tggtctttaa aatctaatag
     9241 gcctgaatta tcaagggctt tttctgccaa tcgctggcgt tcttctttgc gaacgccacg
     9301 taattccaaa ccaaattcgg tattttccaa aatggtttta tgaggaaaga gggcaaagct
     9361 ttggaaaacc atgttaatgt catggcggcg cacctcacgc agctgatctg ctgacatggt
     9421 tgagatgtct ttaccttcca gcaagataga tcctgccgaa ggttcaatca aacgatttag
     9481 catgcggaca agggttgatt tcccacttcc tgatagcccc ataataacaa agatttcacc
     9541 ttttttgacc tcaaaactag cgtcatagac acctacagta gcgcctgttt tcttaaaaat
     9601 ctcgctctta tttttgccag tctttaccat ctcaagagct gctttttgtt ttttgccaaa
     9661 aattttactg agatgtttga cttctaaaat tgtttccatt cgttttttct cctaggtaat
     9721 cgtttatcat gtgaaatagt gacatagctt tggcgaaata ttagccaata tttaacaaag
     9781 tagctctaca caattaataa acgtgtggtc acttttttac ttaaaaaaag aatctgccga
     9841 aacagaacat aactatatta tcacgtgtgg tcactttttg tcaaggacaa taactcgatc
     9901 tggtaacgcc acaatgatag gtgatcgctt tcattctttt aggtatggtc ttttaaccag
     9961 tacaattttt tatcacaact gatgactatt tctttgctga ttaggctatt gttacattag
    10021 aaatccttct tttacctata atatctcttt tgcggccatc gtaaataacg accacggtga
    10081 ctcttaaaca tttgctcatc tctccaaaaa aactcaccta agacagtgtc ctacgaagcg
    10141 agttagctta atcaggcact atcatcttag gtgagtaggg tgttgcttat agtaaagctt
    10201 taaattggat attagaatct tctaagaagc agtcatcaaa tccacgagga tgatggtatt
    10261 cgatacgatt ttggtcttgt ggataggtgt acttgccacc aacctcccag ataaagggat
    10321 ggaaatcgta ttggagacgt tctttgcgca ttttccacag ttcaaggatt tcatctgttg
    10381 atgccataaa gtttgaccaa atgtcataat gaactgggat aacgacttta gcacggagat
    10441 tttctgccat acgaagaagg tcaacagaag tcatcttgtc ttgaatccca attgggtttt
    10501 ccccatagtt atttaacaca acgtcaatat cataatcacg tccatgttta gcaaagtagt
    10561 tcgaaaaatg agaatccgca ccatgataga tggtaccacc tggtgtttca aaaatatagt
    10621 taacagcttt gcgagccatg tcatcatctg tgatagctaa acctgctaaa tcaccatctt
    10681 gagcatcagc accttgtatt gggagagtta ccagacaggt gcggtcaaac gactctacag
    10741 cggtgatctt aatatctttg aattcaaggc tatcacctgg ctttaagatc ataatacgat
    10801 cttttggcac accccaattt ttccaaactt caccacattc ataaggtcct acaaatttaa
    10861 catgattaag ttttgggtta ttgataatgg ctgccgcagt attgatatcg atgtggtcac
    10921 tatgataatg agaaaccaaa taataatcca actcattaat cataaatgga tcaatcacca
    10981 ttggttgggc cctaagattg ggctgtaatt tacgagctcc tgccatatta gccatttgat
    11041 gtccacgaac catatcctta acttgcttgg tcgctttccc acgatttgac cataagtcca
    11101 tgacaacatt agcaccgcct ggtgtcttaa tccagatacc acagtttcct aaccaccaca
    11161 tcgcaaagtt gtcagctggc acgacttctt gctcgatttc ttcatttaac catgttcccc
    11221 attctggaaa cgtgttaagg atccatgatt cacgtgtaat atcttgtact ttagtcatta
    11281 gggtttcctc cgaatttgtt cttcgtttct atactttaag tatagacttt cttgtcaatg
    11341 ataaaaagac caagtgtcac acagatctgt gttcaaaagt ggactgactt tttcattagc
    11401 tcagtctaat actgtctcat tttgcacact gtatctcgca tcaatactgt attcaaagct
    11461 atattaaaaa cctcagttat atttttctat gtcatagaaa actgaggtac tttgacgact
    11521 taacacttac tcatagcagc tcgcgatgaa tgagtttttc aattttagaa accaaggcat
    11581 aacgatctga ttcatctttt acaacagctt caatagcttt tgtgagctct gtagaaaagc
    11641 gggagtgctc actcaagcgt ccttgctttg aaaagcgtat caatttgatg atatcatcgt
    11701 cacttaaaat agggttaaca ataagcatcg ggattttagt ctttagcgta tctgtagtag
    11761 caacaatcat atcgactgct aaaaggtcgt aaacactctg atactgttct gtcgtaaaaa
    11821 cagcttcaat ctgaccattt gctagatacc tttgacactg tttgaacaat aacttttgaa
    11881 tgcctatccc atcatctgaa acaataacga gtttggtctt ttcttgctct gtattattgt
    11941 gacgtagctc tcccccaaga tggatagtca agtaggcaat atcatcgtct gtcaagctaa
    12001 tcgtccaatc ttgttccaaa atagtggcac aagattgagt catagcaaac aattcttcgt
    12061 atttttcttt aatatggtct gttaagggat taactaaaaa aatcccataa gctttacggt
    12121 aaacgagcgc cttacagtgg gtcgtcaact gcttcagcaa atcctgttta tgcgtgaaat
    12181 gtaactgata acggctctcc aactggtcaa taaagtgact aatggttgct cgcatgtcgt
    12241 cataatcttg actttccacg tgatgatctt gatcttttcg aaaagacaac atcaacatcg
    12301 ctaccatact aacttcgata tcatccaaat gaagcttaaa attatggtaa agctctctag
    12361 ctaaatcctg agcaatgtga tattctttac gtttccaaat caaatgaaat tcttgtttaa
    12421 gagcagactt tgtttctgaa tcaagacgca tattacgata acttaaaagc atgaaaggta
    12481 aaatctgcaa catgaattgg ctatcttggg tattaattgt ctttcctaag ctagcttgag
    12541 ataaaaagag atactcatga aaataagtca aaatatcttt agaaaaataa accgataagc
    12601 cttgtatctc tgagagttta cggttgaata tatcaataaa gctagtattg ccaccttggt
    12661 aaacgtccac taacaatttg tacaggtatt gaataagagc cattggatga caaccaaaat
    12721 aatatcccct agcctttgtc gcatgaagct gaatcttgta ttgtttgtct tccagttctt
    12781 cccttaactc agtcaggtca tttaaaatcg tgttacgaga cacatcattg atctgcatca
    12841 gtttatcaat ggtcacgcgc tcagtggaaa ccgcaatata aatcgaggat aggcgtctgc
    12901 gctcatcact tttcatgaca taattataat cagtcacttc ttctaataat aagcgacaag
    12961 cagctttttg atcagctgtt aaaagaatgc caagtctagg ataagagata atctgatcta
    13021 ctccctttgg caaagcctga ttaattttgt caagctggta ataaacttta cgacgtgact
    13081 gatttaaagc atgagaaatg gccataactg tctcaggtgt ttctagttta agtaaataag
    13141 acagcaagtc ataactcttt ttatctaaaa tcatcatgtt tacaaacctc ctctctaaaa
    13201 atccatcctt gcttatttta tcatgatttc agtgactgcg cagccaagtt ttgaaaaact
    13261 caccataata agattcgctt aatatgattc gagctaatca cctcaactga tccaacacca
    13321 acaccttata tctggtctct aagaactcca caacatacga ttcatccagt ttgtgctcat
    13381 tggcgtttaa acagttcatc gaaaaggaca agtcaaaagg acttgcccaa acaatgatta
    13441 acaaaacctt gaactttctg gcttctagtg agaacctgtg ctaataagcc atatcgcgac
    13501 ctcatttttg accgtaataa gcatttgggc catgtttacg caaataatgc ttatccataa
    13561 tgtatcttgg cgctggctct acgcgtggat tgatttgttc tgtcaagcga ttcattttag
    13621 ccacttcttc taagacaacc gagtggtaaa cggcttgctc tggggttttc ccccacgtaa
    13681 atgggccatg attacgcacc acgattcctg gaaccgccat cgggtcaaga cctcgcttgc
    13741 taaactcttc taaaatcacg ctaccagttt cttgctcgta agccccatca acttctgctt
    13801 ttgtgagaga gcgagcacaa ggaaccgggc cataaaaata gtcagcatgg gtagtcccat
    13861 aaaacggaat atcacgacct gcctgtgccc agccgacagc ttctgtggag tgagtgtgga
    13921 caataccgcc cacttctggc caagctttat aaagttccac atgggttggc aaatctgaag
    13981 aagggttcaa atcaccttcg accacattcc catcaaggtc tgtcaccacc atattttctg
    14041 gtgtcaagag gtcgtagtcc accccagaag gcttgatgac aatacgtcct aattcacgac
    14101 aaacttcaga gacattgccc cacgtaaatt tgacaagacc gtgttgtggt agagacttgt
    14161 tagccgcaca gacacgttca cgcatttctt gcaagttttt cgccatatta tgccaacccc
    14221 gctttctcaa taagtgggta aaggaagtcc tgagcttctt tgatagcagc ttttgtttcc
    14281 tccaccgtgt cacaattttc tgaccacatt tcaatcaaaa aaggcccatt gtagttggtt
    14341 ttcttgagga ccgcaaacag ctcttgccag tccacacaac cttgaccaaa tggcacatca
    14401 cgaaactgcc cttttgaggt ttccgtgaca gcataagtat ctttcaagtg gagggctgca
    14461 atggacttgt gaccgttgta aaattcactc cacaaatcat tatgccaggc agaaacattg
    14521 cctgcatcag gataaacaaa gagataaggc gagtcaatct ctttttcaac tgccaagtat
    14581 ttttcaatag agttgataaa agggtcatcc ataatctcaa tagaaagcat cacttgggct
    14641 tcttcggccc agtcacaaga ttgtctcaag tttttgataa aacgagcacg ggtttcaggc
    14701 gatttttctt catagtaaac gtcataacca gctaattgaa tggtacgaac gcctaagtcc
    14761 tgtgccaatt caatacattg tttcatcagt ttaagggact tggcttcaat agcaggatca
    14821 tttgagccta gtgggtaacg tctatgacca gaaaaacaaa tggtcgggat gcgaatgcct
    14881 gtttcataaa tggctttcac taaatcaagc cgttcttcct tagtccactc taagcgcgct
    14941 aagcgagcat ctgattcatc aacagacatt tccacaaaat caaaacctaa gtcttttgca
    15001 aattgcaagc gttcacgcca ggtaaactgt tttggcgttg ctttttcata aataccaata
    15061 ggacgcgcca taaagttacc cccagatacg tctgatttca tctttgaagg cacgcgccgc
    15121 tgcagcagga tcttctgctt cagtaatgcc tcgccctgcg ataaaggtaa agacatcaac
    15181 cccttcaaaa agtttcaaag tgtctacatc aagcccacca gttactgaca cgcggaagcc
    15241 catgtcaatc aatgttttca ccttgttaag gtctttttca ccccaagttt ctccagcaag
    15301 aagggcatca cgagattggt ggtaaatcgc ttgggaaatc ccagcgtcaa gccataattg
    15361 agcttgctca taagtccaat caccataaag ttcgatttga atttccccac ggtcaccgcg
    15421 ctcttctttc atagccttga gggctgcttc catggttgga atcgtcgcac agcaaatgca
    15481 ggtcatccag tcagcaccac gttttgcatt gtttttagcg accgtaccgc cagcgtcagc
    15541 acatttggta tctgctacga taattttctc tgggaagagg ctgcgtaata cctcaactag
    15601 ttcgcttccc acttgaagca aacaaacggt accagcttca atcacatcta cttcgtgacc
    15661 cacagcaacg gctgctttga tagccccctg caagtcagaa tggtctaagg caacttgtaa
    15721 atttggaaga tgtgtcatgt gtttttccta gaactctcag cggctatgaa aaagctgatg
    15781 aggagttctt atcctttcaa taatgattgt gagtcgtttt atccgtttaa gtcagtaagc
    15841 tatcaattaa gagtctaaat ccaaaccttc taaatacggg ctattttttg attcttctac
    15901 catttctaga acctctttag gactttggca ggccaccaag cgttcaatgg cgttatctag
    15961 ttcaaacaag gccacaattt gtgggatagc cactgttgtg tgaatagaag ggtctgtagc
    16021 ggccaacgtc aaaagaacag aaacctcttt accatctgag aaggtaactg gttttgttag
    16081 tgtaatcaaa gcaaatgcat tgcgattaac gcctaaacct gcttctgcat ggggcatagc
    16141 catacctggc atcaacacat aataagggcc gtatttttct gttgatgcaa tgatggcgtc
    16201 gtagtaagct gacgtcactg ctttgctatc aatcaaaggt tgaacagcta attgaacagc
    16261 ctcttgccaa gtatcagcac ttagccccaa tcggatggag ttgttgtcaa taaaggcttg
    16321 ttttaaattc ataaaaacta tctctttcta gtgtcttgct ttgcaacaca caccattttt
    16381 actagtttta tcctactaaa gagaaagagc tgaaaacctt cgtcacaact ccttcgtttt
    16441 gattcagaat tagcttatag cacttcttgt agtttggttt taatttcatt atcatccatc
    16501 aggttatcaa gaccaaccaa gtggcctttg gtacgaccat caagctcatg aatcaagtgg
    16561 tttgatgcca ctacaatatc atagccagaa gctagacctt tagcttcacc aactgagcaa
    16621 gaagctgact gaatatctgt cacaccaagt tgacgaagcg cattttcaac tttcattttg
    16681 atcaccatag atgaccccat accattgcca catgctgtta agactttaac cattgttttt
    16741 tcctccgaaa atgttttatt attgttttgt taaaatagca gagctatttc ttaagatgca
    16801 gtgttattga gcttccccac ggtagtaagc ttctttgtcc ttagcttttg cgaactgcaa
    16861 ttgtggaatg gcaagtaaga agatgcaaac aagcacatac cctgcaatac caaggaattt
    16921 gaagaggtac ccaaatggta accatggaag aaccaagtcg atattaccgt gataaccacc
    16981 tgtaagtcct aaaagaccta cagcaacagc accaagtgcc acctgaataa tacctgagat
    17041 aaatgataga gctaccgctg ctttccagcc accacgttta tcagcataaa ccgcaattgc
    17101 cgcattatca aagaatacgg gaacgaatcc tgtgataatt aagattggat ttttaaagat
    17161 aacaagaaga gcaatggtga ttaattgacc aatcaaacca aaggcaaatc ctgaaagcac
    17221 cgcatttgaa gaaccaaagc cataggaagc tgcaacgtca accgctggga atgaccctgg
    17281 aagcaatttg cttgagatcc cttgaaaggc attggtcaat tcagaaacaa acatgcgaac
    17341 accctgcatc aagataaaga gataaactga gaaggtgaga gaggtttgca aaatatacat
    17401 gaagaaagct tgcttagctg ggttgaatgc tccaggtccg attaagtcca catcagacat
    17461 aatgtctgga ccaaggacag ccaagatagc tccgaaaaag accaacatca aagttgctga
    17521 tgcaacaaca gtatcatgga aaatgtttaa gaaggttggt aattttaggt tatcaaggtt
    17581 ttcttctttt ttaccaaaga acggtgcaac cttatccaca aaccaaatcg caaattgttg
    17641 ttggtgacca atcgcaaacc caccgccacc tgtaaggcgt tgagttgctt caacggtcat
    17701 attagaactg atagcccagt aaagcccaca gatgatacca actgcccacg ccccaaaagc
    17761 attttggaat tgagggatta aaagaaggac aaagacagag atagtcgctg cctgttggac
    17821 catgatgtgg cctgtgatga aaagagtacg aactttagtg accttacgaa gtgcaaccaa
    17881 aagaatgttg accccaaatc caatcaagag agctgtcgta gcaacactga tgaagcccat
    17941 ctcttctaac ttagtattag cagcagccaa accaaaataa ggatcaataa cggcggcttt
    18001 caattcaaat ttcttggcaa gagcaaccaa gatcggacga aaagtcgtta caagaccgcc
    18061 tgctccaacg ttcaaaatca agtaaccaac agtagccttt acaaaaccag caaagacctc
    18121 ataaatgggt tttttaagga gtaaataccc gattaaaacc aaaagaccta caaagaacgc
    18181 tgggttttgc aaaatatttt gcgagaacca gtttagggga gctaggagca tttccataag
    18241 aactacctct tttcaaagtt aataaagata aagtgtttat atgttcatta taggtaatga
    18301 aagcgtttta aaaaagacca actatcacac aaagaagtgt tcaatattag acttaagtta
    18361 acttatttta aaatttaact acacttaata ataaggagga aataccccta aacaacgatt
    18421 aaaaaccaca aaaacgaagg ttcttgtggt ttttctagat gagttgcttt ttgaatagat
    18481 cagctctttg gcattaactg tgacgtgacg caaataacca ctgaagggct gtgtcaagtc
    18541 aaactatttg ataacaatat taacgagttt gtttggtact gcgatgactt tgatgatgtc
    18601 tttgcctgcg atttcggctt ggactttttc gttagcaagg gcaacttctt gcaattcttc
    18661 gcgtgaaagg tctttggcaa ctacaagttt agctttgacc ttacctttga tttggacaac
    18721 gatttccaca tcgttttcaa ccaatttgct ttcatcataa cttggccatg gcacgtaaga
    18781 gattgactca cctgaggctg tcaaggcttg ccagagttcc tcacctaagt gcggtgcaaa
    18841 tggtgcaatc aattgaacaa agcctttggc atagtcgcta aagagtttgt cttccttgtt
    18901 ggctgcattg acaaagacca tgagttgagc gatagctgtg ttgaatttca tttggtcaac
    18961 ttgctcagta acggccttaa cagtttcgtt gtaaaccttg tcaagggctc cgctattttc
    19021 ctcagtaatc tctttagacg tgatcaaacg gtaaacacgg tccaagaact tacgtgagcc
    19081 ttcaagacct tcttcagacc aagcgatgga agcgtcaagt ggtcccatga acatctcata
    19141 aacacgaagg gtgtcagcac cgtactgctc aacaacatca tctgggttga caacgttctt
    19201 aagtgattta gacatcttag ctggtgcttg ttcaagctct tcaccagttt ccacatggaa
    19261 gaagctgcca tcacgttttt caaccttgtc agtcgctaca agcgctccac ggctgtcgcg
    19321 gtagcttgtt cccaaaatca tcccttggtt aaaaagtttt tggaatggct ctttggttgg
    19381 tacgacaccg agatcgtaaa gaaccttgtg ccagaagcga gcgtagagaa ggtgaagcac
    19441 ggcatgctct gcaccaccga catagatatc aactggcaac cattgtttga ggagttcctc
    19501 atcagctagt ttttcggtgt tgtgtggatc gatgtaacgg agatagtacc agcttgaacc
    19561 tgcccattgt ggcatggtgt tagtctcacg acgaccttta acaccatctt cacgagtcac
    19621 ttccaaccag tctgtcacgt tagcaagtgg gctctcacca gtacctgaag gacgaatatc
    19681 cttagttact ggaagaacca gtggcaactc actctcagga accgctgttg aggtcccatc
    19741 ttcccagtgg atgattggga ttggctcacc ccagtaacgt tgacggctaa agagccagtc
    19801 acggagacgg taagtgactt tttcattacc gacgccttct gcttcaagcc attcgaccat
    19861 tttggcaata gctgacgctt tgtcaagatg gtctaggaag cctgagttga tgtgaagacc
    19921 gtcttctgta aaggcagcct cttcaacatt accaccttca agaactggaa tgatatctag
    19981 gttaaattgt tttgcgaatt cccagtcacg ttcatcgtgg gctggaacag ccatgatagc
    20041 accagtaccg tagctggcaa ggacatagtc cgcaatccaa actggcattt cgttaccatt
    20101 aactgggtta atcgcatagc tacccgtcca gacaccagtt ttttctttgg caaggtctgt
    20161 acgagcaagg tctgatttga gacttgcttg acgtttgtag tcagccacgg cttctgcttg
    20221 gtcagctgtt gtaatagcat caaccaaggc atgctcagga gcaagaacgg cgtaagttgc
    20281 accaaaaagg gtgtcaggac gtgttgtaaa gacagtgaag tccttatctg tatccttaac
    20341 cttgaaggtt acattagcac cagttgattt accaatccag ttgcgttgca tgtccttgat
    20401 tgattctggc cagtcaactt cttctaagtc ttctagcaag cgctctgcat aggcagtgat
    20461 tttgagcatc cattggcgca tgggttttct gacaactggg tagccgccac gttctgatgt
    20521 cccatcaggg agaacctctt cgttggcgat agctgttccc aattcttcaa cccagttaac
    20581 gggaacttca gcttcgtagg ctaggccttt ttcataaagc ttagtaaaga tccactgtgt
    20641 ccacttgtag tagttagggt cagttgtgtt gacttcgcga tcccagtcgt atgagaatcc
    20701 gagagcgtta atctggcgct taaagttagc aatgttttca gctgtaaact cagctgggtc
    20761 attaccagta tccatagcgt actgctcagc aggaagtcca aaagcatccc aacccattgg
    20821 gtggaggaca ttgtgacctt gggcacgttt gaaacggctg agaatatcag ttgctgtata
    20881 gccttctggg tgaccaacgt ggagaccagc tcctgatggg tatgggaaca tatctagggc
    20941 ataaaactta ggttttgatg cgtctgttcc tgttttaaag gtatgattat ctgcccaaaa
    21001 ggcttgccat ttgggttcaa tagcggtgtg atcgtaaaat gtcatgtgaa atctcccatg
    21061 taaaaaatct agtcttctta ttatagcatg agatgaagct tttaggaatg gtcaagacat
    21121 gactagcacc ttggcttttg agacttcaga cgattagcta tttttaaacc ctgctttagc
    21181 atcaaccatc ctcacaaaaa gctaataaaa aagccagact tgctctgtaa acagagccaa
    21241 tctggacaaa tagacttaaa aagcaagtgc ttgctcaaaa tcggccaata agtcttcgat
    21301 attttcaaca ccacaagaca agcgcagcaa accatcaaca accccttgtt ccaaccgcgc
    21361 ttgtgatgat aaacaagcat gagacatcgt tgctggatgt gacaaaatgg actctactcc
    21421 acctagacta acggctaaaa tcggcaactg aatacgatgg gtaaaggtca tcagctcctc
    21481 cttagaagcc aactcaaagg ataaaacagc accaccattc ttagcttgtt gcaggtgggt
    21541 atcgtgatta ggatgactgt ctaagccagg gtaatgtacc ttaagaactt tggggtgctt
    21601 cgctaaatag ttagcgagct gctgagcatt ttttaccgct tgttccatac ggatccccat
    21661 agttttcatg ccacgaagaa tcagccaagc gtcttcgacc ccaacaattg ctccaaagtt
    21721 tttttgaaaa agcttgagct ggttgtagat agcctcatta ttggtagcag ctaaaccagc
    21781 taccacatca ctatgaccat tgataaattt tgtcacactt tctaccacaa tatccacacc
    21841 catagctaag ggttcttgat acaaacttgt cataaaggta ttatcagcca cagttagcac
    21901 accataagct ttggcgagtt gcacaagctc tgaaatatca caaattttca agagcggatt
    21961 tgacggtgtc tctagataaa tcatacgcgt attaggcctg atacttgctt ttactgttgc
    22021 taaatcagcc atatctacaa agcttgtttc aatctgataa ttgggtaaaa tagctgtcgc
    22081 aaattggcaa gtccctccat agacctccaa tgggaaaatc acatgatctc cagcttttaa
    22141 gagcatcaaa acagttgaaa tagcagccat accagatgca taagccaccg cataagtcgc
    22201 tttttctaaa caggctaacc cgtcttctaa agcttcagtc gttgggtttg aaaagcgtgt
    22261 gtacaaatgt ttttgactag gacaatacag ttctgaattg tggaacgtcg aagtctgata
    22321 gatgggaact gaagctgctc ctgtaaactc gtcaataacc gtatagccat gtaataaggt
    22381 cgtattttct ctcatttcgt gcacctccgc aatagcgtta actccaatga actctctttt
    22441 agacaatggt cccaccccaa tggttgcaca aaccaaaaag ctcttcaaaa aagcgtgatc
    22501 tgctaaccta ataagaaaag tagtgggcac cttttaaatg gataatgaat ttttccaaca
    22561 atatcatttt tagatcgatt acgtttatta tacaaccttt agctaagttt gcaagccctt
    22621 ttatcatctt tgaccaagct gccaacacct ctctagcaag ttaaagtata gctacctttg
    22681 gccccatcgt ctcaaaagct tagcttatca cactgacagt cctactttgc atcgtcacct
    22741 actcaatagg gcaatattgc catcaaaatt tcattaaaag gtcacaattt atttcattta
    22801 atgagaaaca gaacttgttt tcaccatgcg ccttatagta cactgctaaa gtactattta
    22861 tttttaggag agaaatatag tgaaaaacaa attattttta gttgcccttg cgaccgtaac
    22921 tgtcctaggg ccgtctttag caacccctca tcaccagacc gtgcatgcgg ctgagcaggc
    22981 actggcagga acatgtacat actctaatga gaatccttat gtaggtgttt gcttcgagag
    23041 aaaagatggc atgccaatag aagaaaacat tatcacaaaa aataacgatt tttcccttct
    23101 taactggttt tgggagatag ttaccaattg gtggtcaaaa ataacaggtt atttttcgta
    23161 atactagtca cagcatagtc taccgctaac tattaaaata aaaaaccatc tcgtggcggt
    23221 tttctaatcc taggtcgcca catttcttat tcagatgaat aataataaaa acattaaaat
    23281 aatacttgat ttattaacaa aaagttagta taatatagtc atactacaaa ttaaaggagt
    23341 tatctatgaa aaagaaatta tctttattta tgatcgcaac tgctgctgtt gcaggcctta
    23401 gccttgcaac actaggagag caccaaactg tttcagcaaa tgatgctaac tatagtaacg
    23461 gtttctacgg acacaatggt cctgagagct ggttacttta cacagtatgg taaacctcat
    23521 accgtaacat agaagctatc ttcttcgtaa gactacggtt atgaaaagcc tagggctgca
    23581 taagcagcct taggcttttt gattggctaa aacgtttttg ccaatgaccc ctcaaggtaa
    23641 aacagaaaag gcacaatgcc tataaaaaga gagaagccca aaacacaagt cgtaacagtt
    23701 gctagctaac cagcaccaaa aaagctgtaa cacctcaaat agaatgataa tcagattaat
    23761 attattaata attaatgtga tttatataag ataaagaaat gctttagtct tggctttctt
    23821 tgcctttttc ggtcaaacat attacaaaaa gattaaaatg tgatattgaa tcattaatat
    23881 aatatgagta taatatatgt atactataat ttaaggagtt acaaatgaaa aagaaattat
    23941 ctttatttat gatcgcaact gctgctgttg taggccttag ccttgcaaca ccagaaaacc
    24001 aaactgtttc agcaaatgag gcagtagcta ctcaagcatg taattacgat ttttacggat
    24061 attgcggacc tatcagctgg ttattctata agacaaaaca cttgttgatg ggagagcagc
    24121 ctactactac ttctacggct acagtcacaa aatagtgaga caacagttat aaaaaagccc
    24181 aggactgcgt aagcaggctt gggctttttt gctgtcctaa agttagggtg ttgccacaac
    24241 ttcaaaccca aagacactta aaccgcaccc caacaattag acataggcta tgtccccaga
    24301 atcctggaca catatcacta aagcctaatg attaaggtgc ggtttaaggt gtggtagcaa
    24361 ggaactgttt taaattcgtc tgcgtctaac tatacccact agctatggag tcagcttaga
    24421 gttgattgtc aaatgtcagc tcaacatttc ccaccaatgt aaaatgattc cccatataaa
    24481 ctggacagga attaacaaag ggtagtgttc tccaaatcct tcattataac cctctttgta
    24541 cccatctgta tacccttctt tataaagctg tttattagta tcttcaatat catcaggtgt
    24601 ttctagatca gttgggacag ttggggtcaa atcagtccaa gtagcttctt ctccagcttt
    24661 tctccctgct tctgtacctt tttctaaacc ttgactataa gctctatcct caggagtttg
    24721 ctcctcatct gccataacag gtcttgctac aagcaacata gcagcaaata gagccaccaa
    24781 gaggtagacg aagcgtagag gctggtaaga ttgttgtttc atgataatag ttatctctcc
    24841 cttttatgtt atgctttgct tgttaaaaag cagcttgtta gtattataga ttagaagcag
    24901 cttagcttca aggtcacgat gtgagaaaag aataattttt tgattagtat ataaaaaagc
    24961 ttgtctatga aggtatctca taaacaagct tttttctgta tttgtgagag gagtaggcac
    25021 aaggcctcaa gagataagca gcatcaagct gtttgacgaa cctcttgaac cagtcctatt
    25081 tataagtaat tgaaccatat gggctcaggg ttgatcctga gatgttgaca ttgatttctt
    25141 tagacagttt cacatctctt tcgtcgatca cttttcgcca ccattcccaa gctaagccgg
    25201 tgcactctct agccatgata cggatatttc gtgaattagc tcctagtggg ataactgtgc
    25261 taaatggtga tgtcttacta taccagttgt tgtcccaacg tcgttttgta atcacttctt
    25321 ttcctttgtc atcataattg atttcatccc aaaggatttc atattgagca acatacgcgc
    25381 cttgatgaga caggttaatt tttccactag tgtactcggt agatgttgtt tcaacgtatt
    25441 cagttctgtt attgacaccc gcaattttat tatttttaag gaaaacactg gtgtatgaaa
    25501 taggataagc tgggtttttt ctactgaagg tagcattgtc tttgataacg tttctaataa
    25561 catcaaagtc ttttgtgact accttattgt gctctgcagc atctcctcct aaaacgacag
    25621 ctgtaaatga actattttct aagatatcag agtattttcc attcgtttta acatctgttc
    25681 cttttagagc tgcactaaag gccgcttcaa catcattact tttagaactt gtttctagtt
    25741 tgacaaaaac agttcgacca taggctacgt tactcacaaa gagtggagga gcttcattgc
    25801 tgacaccttt tcgttgcaaa tctttaaagg tcactgattt atcaaacaca tccgcaggat
    25861 tattaggaag gtttgctgat acggtgtaaa aaatttgctt gtatgctgca atcatcacct
    25921 tcttttcacc ttttgaaatc gacttgaaat caatgcctaa agtaccatct aagattttgc
    25981 tattaacatt tagagctgct tcaatctgtg acttagaata taccattgat tcagtatatt
    26041 gtgttctggc aggaagcgta ttaccaccag aataattatc atgccattgg ttaacaagat
    26101 tatcaatagc tgttgaaaca ttggcatagg tagggtcatt gacctcaacc gttgctttgt
    26161 ctcccatacc tggtaaatca atatggattt tttgtgggtt tcgcttggtg actaccgcgt
    26221 ctggtttgtt ttcggtaaaa cctttatcag ccagctgaag ggctgctgga taggtcatat
    26281 cagtgacaga gtcaatgatg gaaatatcga ctggtgtagt gttgatattt tttttctttc
    26341 tttcaatgac aataaattta tcagctttct taacgccttc tttaggaaca aaattttcaa
    26401 tggtttcacc atttttagca agtacttcaa gctcattata atttagtgaa taaatcttgt
    26461 cattgatttc ttcagtgtga tcttcttcgc tctttttttt gtcttctgac tttttttctt
    26521 ctttttctgc agattctagt ggcatttctt tgggagcaag cttaatcata tcgttagagt
    26581 taagcatatc atccattttc tgatctgctt tttcgatagt tagctcacta ctttctgctt
    26641 ttggttgctc atttgtcgtt gtggtttctg tactagcagt gttttgtttg ttcgattcag
    26701 cattagcagt aacaagatta ccaatgataa gagctgccgt tagtagccca gcgacgcgac
    26761 tgtatttttt aaatgttttt ttattagaca tgtccttcat acctttttat cattctaaaa
    26821 tgtttctatt gttctttcga ccatatcaag catagtatct tgatagtgag caaattctcc
    26881 taatttgtaa tgtgccatag cctctctaat atgcgcatct tttaacgctt tggttatatt
    26941 agctagtatg ctttgacggt ttaaataaaa tggcaagctt tcgtaataat ttaataacat
    27001 gttttcagcg tttagggttt gaaccgcttg gtaaatgtct aatgcttgac cgctatttga
    27061 catttctaat aatgcttctt cgatattagc tttcaattgg gtatagcctt ttatgaaagc
    27121 agggtaaacc ccatactcta aaataacttc tggatcagaa atatctccca tataagagtc
    27181 tcttctagtg atacgatact ctttgtcact acctatcaag tattttttaa aatcattaac
    27241 agttacttct ttttgaaaca ttttttggta atgttctaaa ccctttggca ccttatacat
    27301 attgttactt cctatcttgc attctatctt gcattttctt aattttgaag cgaccagtta
    27361 cttttttatg gtcaccattt ggagcaatga tggtaggatc aataatttca aaatagcctt
    27421 tggcatcaat ctctgctaag acagctttag attttagatc tttaacacta atcgatggga
    27481 aaattaattc actttctgaa ttttcaatgt gttttcctga ccacgtttgg caaccaggaa
    27541 tgttgagcga atttgctcca ggggtatctc cgctagctgt tcggatatag cctagcttat
    27601 caatgttttt tgttagttca gaatcgtact catattgata aaccccatcg ctatatcttc
    27661 cgctatcgac accttttata ttttcaattt ggtcagctga ttttaactta ccttgatcag
    27721 taaagagcaa tgccatatct tcagcaaaac ttgtcacaaa aagaccgttt tcttgtcgac
    27781 caatcgttga ctttctttta gcatcatcaa aagctaacat caaatctttt ttgcttgtaa
    27841 cgtgggaagc tccgctttct ttgtagactt gttttagttt ttcaacaaac tcttttttgt
    27901 actggtattt gcggctaaca tacatccggt aatactcagc acgtgatgca acagcagaca
    27961 tctgaacagc tttatcagca tacttgtcgg cagtttcaat aaactcatct gcttgtttat
    28021 ctgttaccca tttatcttta atttctttaa actttttttc aaaaagatcg cgttccatat
    28081 tgccaaaagt gacctctgac aaggctaaaa tatccttgtt ttgtccctga tggacctctg
    28141 ttacctcaat atcaatacga tcaacatcta attttttatc aatctcaatg tgatgcggtt
    28201 ttttagtgta ggtgtcgcct aattcaattt tttgaaagag gaccaattta ttcccgttat
    28261 agtatttaac atcagccttt gcaattctat ttttcttgta gtaattctcc ttgctagatg
    28321 tatctccatt aacaattaaa attctcccaa tacgcatcgg ggaagcaaac ttgtaggaaa
    28381 gtacctcacc aacgccacca ccaggtgaat tttcctccca gacagtactc attgagccgt
    28441 ctaatgtgtg catgacatga ttgtcttctt tagaggaagt tgcgttagct tccataactt
    28501 tggtcgtttc atatttgaca tcgctttttt tattttcttt gccactaaca gcgtatgttg
    28561 tgctattagc taataaactg ctacccattg ctccagccaa agcaatagca acacttgtct
    28621 ttgcgacaat atgagctaat gttacttttt tgtttctcat gtaaaccacc ttatattatt
    28681 tttaagtaaa ctatacatta acaaatagtc tttgtcaatg cggtttatta acatcgtttt
    28741 aggcttttct atcaaaaaaa tgaacaaaaa aaaaacaagt agccaactgt tacaagtttc
    28801 aaggggatat ttccatctta ttatcacaga accttcacat ctgttctatt taaaccagat
    28861 taaaagtact agttaaatat ttgatagtag caccgttatc agtaatagat ctgttaatta
    28921 tctctgatta caatgatgtt aacaatagtc atacctttgt ttgtacacac gcttcactgc
    28981 caactaaaaa aggtctgatg gtaatattta taccatcaga cctttgagag cctatagctc
    29041 tgcaatttga taaagttcaa cttctgctac tgtttcagag ccaaacatgt tgagcatcag
    29101 cttcactttg ttgttttcga tttctaccac acgaccttct tgtcccataa aggcaccgtc
    29161 gatgatctga accacatcgc cttctttgat attggtatca aagacatcaa tggtttgacc
    29221 catagacaac aagatagcac ggatttcttc ttcaagaagt ggtgttggtt ttgatcggtt
    29281 cccgtgtgat cccacaaaac ctgtaacgtt tggtgtgtta cgcacaacaa accaagcttc
    29341 atctgtcatg accatttcaa ccaagacata ccctggaaag cgattttctt cgatttcttt
    29401 ggtttgccca tttttttcaa cgttaaccgt ttgtgtcgga atttcgacgc gcaaaatatt
    29461 gtccaacatg ttataggttt gggcacgttg caagaggttt tcttttactt tgttttcgta
    29521 gcctgagtaa gtttggagga cgaaccagcc cttatcaaat gaatctagca tgatgtttcc
    29581 tttcattata aaaaagccct ttttttggct tttgcgctgt tttctatcac cttcattata
    29641 ataaaagaca gggccgctgt caacgtatct gtggagctac ttgacacctt tattaaaaag
    29701 tccaaagtcg gttcgtgacg actctggacg gtattgtaca gttttagttt tcaggaactg
    29761 tgatggttcc ttcgataatc gcttttttag cagtctcaat agctttttta gtgtcttgtg
    29821 tcagagcatc cgttgtaaga ctaacaccac cttcttttaa accaaaagtg gttatttgac
    29881 cacctgggaa ttggccttct gaggttttta cggctacttt tactaaagct tttccgactt
    29941 ccttgatact tgaggtcaaa acaaaattag ctgacttgcc atcttttgtg gtgtattttc
    30001 catcttcact ttggtcacgg tcaacaccaa taacccaaac cttatcttct tctttacgtt
    30061 tttcgttgat agacttagct tcgctaaaga cacccgcccc tgtgcctcct gctgcatgat
    30121 aaataacatc tgcgccttca acgtattgag cagctgcaat cgtcttgcct ttggcagcat
    30181 ctgcaaaaga gcctgcataa gcaactctta ctttgatggt atcatctact gatttcacac
    30241 cagcttcaaa acctttttca aagcgcttga caacatctcc ttccatacca cctacaaaac
    30301 caacttgctt ggtttttgtc gttttagctg ctgcaacacc ggctaggtat gccgcttcat
    30361 ggtctgaaaa ggtgatactt gcaacatttt tttgaccttt aaccacatca tccacaattg
    30421 caaaatggtt gtcaggattg tttgcggcta ctttttctac agcgtcatgt aatggaaatc
    30481 caatcccaaa aacaagatta taaccattgg ttactgctga ctcaaggttt gtggtaaact
    30541 ctgattcatt ggctgattgg aaataatcat agccttttcc tttttcaagt ttattttctt
    30601 ttccccaagc ttgtaagcct tcccaggctg actggttaaa tgacttgtca tcaatacccg
    30661 tctgattagt aatcatagcg atttttaatg aattgtcagt tgtttgttta gcagagttat
    30721 tggtacagcc tcctaatgtg aatagggcag tcgaaacaag accaagtgac attacttttt
    30781 tgttcatgtg aaaatgaacc tcctaaatgt ttaatcctaa agtgatgtgt cattgttaac
    30841 gttctactta tgctctagaa cgaaaagttt agtatatcaa aaaaatcagt tttatcctac
    30901 tatttttgct gaaaaatctc tttctcacca aaatgaccga acgataaagt gagatcaact
    30961 ggtaaaaccc attatctcct caaaaatcac ctcttaagga gataagacaa cgacaaaact
    31021 caagcaacta gtaatagcat gactaactat acaatccaac aaacggtaaa aagagctgga
    31081 aacgctatcc aactctttgt catactagac accttagata gatgcccaga ctgactcaag
    31141 aatattggtc tgttcacgcc ctggaccaac tgagaaggtt gaaatgcgaa cgccaaccaa
    31201 ttctccaaca cgacgaacgt agttgcgggc attttcagga agctcatcaa ggctacgaac
    31261 acctgtgatg tcctcttgcc agcctggtaa ttcttcatag attggtttgc aacgtttgag
    31321 ttgttcaagg cttgctgggt aatagtcaat acgtttccca tcaaggtcat aagccacaca
    31381 aatcttaacc gtatcaagcc ctgaaaggac atcaattgaa ttcagagaga ggttagtaat
    31441 ccctgacaca cgacgactat gacgcataac aactgagtca aaccaaccca cgcgacgtgg
    31501 acggccggtc gttgtcccgt actcatgacc cacttcacgg atacgttcac ccacttcatc
    31561 aaagagttct gtagggaatg gcccatcacc gacacggctt gtgtaggctt tacagacacc
    31621 aactactttg ttgattttac ttgggccaac accagaacca atggttacac caccagcaac
    31681 tgggtttgaa gacgttacaa atgggtacgt tccttggtca atatcaagca taactccttg
    31741 agcaccttca aaaagaacac gtttaccggc atcaagtgca tcatttaaaa tcacagaagt
    31801 atctgtcaca tattgcttga tttcttgacc gtaagcatag tattcttcaa aaatagcatc
    31861 aaaatcaaga ggtgtactgt catacatttt ttcaaataaa cggtttttct cagctaaatt
    31921 aatgcgtagg cgctctgcaa agatatcctt atccagtaaa tctgcgatac ggataccaac
    31981 tcgagcagct ttatccatat aagctggacc aatcccttta atagttgttc cgattttatt
    32041 gtcacctttt gcatcttctt gcagttgatc cagctggata tgataaggta aaatgacatg
    32101 agctcggtct gaaatgcgaa ggttatctgt cgtcactcct tcatcatgca ggtacgccaa
    32161 ctctttgacc aaagatttgg ggttgaccac aacaccatta ccaataacgg aaattttttg
    32221 cgggaagaaa attcctgatg ggatcaagtg aagtttaaac ttcttaccat caatcacgat
    32281 cgtatgacca gcattatcac caccttgata gcgagcaatt acttctgcat ccgctgacaa
    32341 gaaatcagtg attttacctt taccttcgtc accccactgg gtaccaacaa caactacaga
    32401 tgtcatatca ttgtcctaac tttctgaaac acttattctc aataaaaatc ataggcaagc
    32461 taaccactgc ttaaaaacca aaaagaaggt cagatctgta agatcagcaa tgtagctctt
    32521 gatatttaaa gaaaacaggc aggaatctca cctgctagca tatatcttac aacttattat
    32581 agcaaaaaat ggttttttct gctagatttc ttagcattat taaggaaaaa gagaaactct
    32641 ttttttaacc atgataaaca atcctaaaaa aacgaacatt ataagagaaa agcttttaac
    32701 ctcgtttctc ctaagcttta gcagggttaa acgattctct taaaacatta gctcttttct
    32761 ttcagaaata gcggttttaa ggtaaaataa tagtaagtta cctctatgag atagccagta
    32821 aaaacatatc gaggaaatat cacatgatta gaaagtatga ccgcacgagc acaaaaaaga
    32881 aatcactaaa ctggatttgg ctaatcattg ctttttttat gatttcaagc tttataggtg
    32941 gctcttcttt tactgagtca cttctagaca ttttgcctgc catagccatt ggtggtacag
    33001 gttatgctat ttttcgtgtt agatctcatc aaaagcggct agcaaaggcc aaggttgcca
    33061 aacaattaga agatctaaaa gcaaaaattc agctagctga tcgtaaagtt cggctgttag
    33121 atacttattt ggcagaccat gatgacttcc aatataacgt actagctcag caattattac
    33181 cacaacttag tgacatcaaa gcaaaagcta ttacgttaaa agaccagtta gatcccaaaa
    33241 tttatcgtcg tatcaccaaa aaagccaatg acgttgaaag tgatattacc cttcaactcg
    33301 aaacactgca gattgccaca actcttaacc ctcagccttt gaaaacccca tctcctaatc
    33361 ttattaacaa agcacctgag ctcaaaccgt attatgataa tattcagaca gatcatcaag
    33421 ctatccttgc taaaatccaa ggagccgaca atcaagaaga attgcttgcg ctgcatgaag
    33481 ctaacatgag gaggtttgag gatatcttaa caggctactt aaaaatcaaa gaagagccta
    33541 aaaattacta taacgctgct gctcgtttag aacaagccaa acaagctatc caacaatttg
    33601 atgaagatct tgacgaaacc cttcgtcgac tcaatgaaag tgatcttaaa gattttgata
    33661 ttagccttcg aatcatgcaa ggtgctactc aaagacgaac aacgcatcac caaaaagact
    33721 aaaggagtcc ctttatggca gattttaatt ttgacattga ccaaattgct gacaatgctg
    33781 ttgtcaaaac cgataaaacc accgatatta tctcagactt accaactgac acaaatggcc
    33841 aaatctcttt ttttgagaaa ctaagtgctg accagcagac agctattact gccaaagccc
    33901 cggcattggt agataccttt ttagcagatc aaaatgcgct acttgatttt ggtcagtctg
    33961 ctgttgaagg ggtcaatgca acggtcaatc atatcctggc cgaacaaaag aagttacaga
    34021 ttcctcaggt tgatgatctt ttaaaatcaa ccaatcgtga actcaatggt tttatcgcta
    34081 aatacaagga tgccacacct gtggaccttg ataaaaagcc aaactttctt caaaaactct
    34141 ttaaacaaag ccgtgatacc ctgcaagagt tttattttga ttctcaaaac attgagcaaa
    34201 aaatggataa tatggctgca gcggttgtca agcaagaaga taccttagct cgcaatattg
    34261 tctcagcaga attgttaatt gaagataata ctaagtccat tgaacatttg gtaggcgtca
    34321 ttgcttttat cgaagctagt caaaaagaag ctagtcagcg cgctgcggct ttacaaaaag
    34381 acctaaaaac caaagacagt actacaccag actatcaaat aaaagctgat cttttggcaa
    34441 gaactaccga agtcatcaac accctcgaac aacaacacac cgaatacttg agtcgcctct
    34501 atgttgcttg ggcgacaact ccgcaaatgc gtaatctagt caaggtctct tctgacatgc
    34561 gtcaaaaact aggcatgtta cgccgcaata ccattccaac gatgaaacta tctattgctc
    34621 agttaggcat gatgcaacaa tcggttaaat ctggaatgac tgctgacgcc attgtcaatg
    34681 ctaataatgc tgcccttcag atgctagcag aaacaagtaa agaagccatc ccagcattgg
    34741 aacaatcagc acaaagccct actttgtcta tgaaatctgt gacaagtctg gcagaaagtt
    34801 tagtagcaca aaataatggc atcattgcgg cgattgatca tggacgcaaa gaacgagcac
    34861 aactagaaag tgctattatc aggtctgccg aaaccattaa cgattctgtc aaactacgtg
    34921 accaaaatat tgtgcaagca cttcttagtg aaggcaagga aactcaaaaa acaattgata
    34981 aaacaactca cgcataagct aaacatcacc tgtcacgcta cttaaaaagc aagccatcag
    35041 ttaggttaat ccctttgatg gcttgctttt ttactactta acgaataatc gccttgtttg
    35101 atataacact tatcttttat gatgttattt tcataatacg aacaaggcta gcacgctcgg
    35161 cctcttctaa tttcaactca atgtagtgaa tcgtctcttc cagttgcggg ataatagaat
    35221 actctaagcc attgacgcga cgtctagtct tttcaatgtc atcagccatt agttgacaag
    35281 ttttttcaac ttcagctaac cgtaagagct tttctaatag ttcttttgtc ttttggatag
    35341 tattgtccat ctcactattt gagctgaggt aactataagc aaactcacct tgttcttgct
    35401 ctcttgccgt attagactgg acatggaatt taggcacatt gacactcatg atattttcaa
    35461 tatcaatcca taaggtcact tcatggactg gaacagcaaa gagttcttct accattagac
    35521 tattttcaga tgcttttgcc aagacaaact ccttcatatt ggcagcaagt tctttttcga
    35581 gagtttgacg aagctcattg ttttcacgaa ttaaatcaac gaagcggcgc atcaactcat
    35641 cccgcttgtc ctttaataat ttatgacctc ttgtagctgt cttcaatcga tttttcaagt
    35701 tactaagttc catgcgtgtt ggtttaacat ttaatcgtgc cattgatata actcctttcg
    35761 tcaagggctt gaaattgcat ggtcaactca atcatttgca acaaaaacct ttgtcatcgt
    35821 ggtatctgct ttaggcaaat aacgatctaa catatcatct ttaatgcgtt ttaattcggt
    35881 acgtggcaaa atcgacaaca attcccaacc caagtcaaga ctttcttcaa tgctacggtt
    35941 ggtgtaaaat ccttggttaa tgtattcttc ttcaaaccgg ttggtaaagg ccacatatag
    36001 tttatccgtt tcagaaaggg ctgattcacc gagcacaaca gccaattcct tagcttgttt
    36061 tccttgggca taggctgcaa agagctgatt cattgtggca gcatggtctt gtcgagtctt
    36121 accttcacct gaacctttat cttttaggcg agatagcgat ggcaagacat taataggcgg
    36181 tctaaaacca tttttatata gttcttgcga caaaataatc tgaccttcgg taatataacc
    36241 tgtcaaatcg gggatagggt gggtaatgtc atcttctggc atggttaaaa taggaatttg
    36301 agtcactgac ccttttttcc cgatcaagcg accagcccgt tcatataagg tggagagatt
    36361 agtatagaga tagccaggat aacctcgtct gcctggaact tctctgcgag cggctgatac
    36421 ttctcgtaag gcttcacaat aatttgtcat atctgtcatg atgactaaaa catgcatacc
    36481 tttttcataa gccaagtatt cggctgttgt cagagctata cgtggtgttg caatgcgttc
    36541 aatagcaggg tcattagcta aattaataaa taaaacagat cgatcaatgg cacccgtttc
    36601 acgcaagtca ttcataaaga attctgcctc ttcaaaagta atacccatag ctgcaaacac
    36661 aaccgcaaag ttatcatcag agtttagaac agttgcctga cgagcaatct gtgcggccaa
    36721 ttcattatga ggtaaccctg agcccgaaaa aactggtaac ttttgaccac gaacgagggt
    36781 attaaggtga tcaatagctg agatacctgt ctggataaat tcgtctgggt aatcacgagc
    36841 gacaggattg atcgcttgac catcaatatc aaggtatttt tcgggaataa gttctggacc
    36901 gccgtctatg ggctgcccca ttccatcaaa gatgcgccct accatatctt ctgatacggc
    36961 taattctaaa ggatgccctg taaatcgaac cttggttttg gctaggttga tgccagttga
    37021 tccttcaaat agctgtacca tagccttgtc accttggact tctaagactt gacctttacg
    37081 cctttctcca ttatgcaaag taatatctac caattcgttg tagtgcactc ctgcaacttg
    37141 atcaacaatc atcaaagggc caaccacttc gctaaccgtc cgatattctt tgagaacgct
    37201 catctaaatt cctccctttg ctaaaacgtg atgaatctct ttggtaacct tctgagtaag
    37261 ccctttaatc tgctctaagt tttcttctgg gataaatttg ctgcgtgcga tgcgatcacg
    37321 tacctgagca gtgccttcca taatctcatt aaaataagct cccaaagaaa gggctttgct
    37381 ggcttcctca ttaaaggtca aaatattggt tagcatggcc tcttgtttcg gaaaggaagt
    37441 aaaggtatcc accgaatcaa aggcattttg ctggagataa tcctcccgaa tttgccgggc
    37501 aacagccatg gtcaaacgat cttgttcaga cagtgaatca agccccacca agcgtacaat
    37561 ttcttctaga ctggcttcac gctgcaaaat agccatggca cgagttacct tgttggacca
    37621 attagattgc tgtttacggt caatatagct tcctacatca tcttgataca atgaataaga
    37681 cgtcagccag ttaatcgctg ggaagtgacg ccgttgcgca agaggcgcgt cgagccccca
    37741 gaaaactttg acaatccgaa gggtgttttg agtgacaggc tctgaaatat cccctccagg
    37801 aggagaaacc gcgccgatgg ctgtaatggt tccctcacgt tcttgacttc ccaaggtccg
    37861 aacacgacca gcccgttcat aatattcggc aatacgactc cctaagtaag ccgggtagcc
    37921 ttcatcacca ggcatttctt gtaggcgtcc tgacatctcg cgcagagctt ctgcccaacg
    37981 tgatgtcgag tctgccatga tagccacaga atagcccata tcacggaaat attcggcaat
    38041 ggtaatacct gtgtaaatcg acgcttcacg cgctgctact ggcatattag aggtgtttgc
    38101 aattaacacc gtgcgctcca taatggactg gcctgtattt gggtcaatta actctggaaa
    38161 ctcattcaaa acgtcggtca tctcgttgcc gcgttcccca caaccgacat aaataacaat
    38221 atcaacgttg gcaaatttag ctatttgatg ctgcacaact gtttttcctg ccccaaatgg
    38281 tccaggaacg gcagcggcac caccttttgt aacagggaaa aaggtgtcaa taacccgttg
    38341 acctgtaacc aaaggttcga ctgggataag cttttgagca acagggcgac tttgacgaac
    38401 tggccaagtc tgcatgaggc taccttggta aatggaaccg tcttcctgct taatttcata
    38461 aactgtatct gttactgtga agtcccctgt atgaatagcc accaaggtcc ctgaaacttt
    38521 ataaggaacc atgatacggt gctcaatgac agctgtttct tgcacagttc ctaaaatatc
    38581 acctgcaact acttcttgac caacacttag cttgggaata aatgcccact tagcctttcg
    38641 atcaagactt gggatagcca caccacggat taaaaagtcg ctgtccgttg ctttttgaaa
    38701 acgatcaagc ggtcgctgaa taccgtcaaa catttctgaa atcaggcctg ggcctaactc
    38761 gaccgacaaa ggacaaccag tagtcactac tggttctcct ggaccgatcc ctgatgtttc
    38821 ctcataaacc tgaatagacg cttgatcgcg gcgcatttca ataatttctc cgactaagcc
    38881 aagatgtccc acacgacaaa tatcttgaat attagcttct tgcatcccag aagccacaac
    38941 aagaggtccc gaaacggtta ttatttttcc ttggttcacc tttttcctcc tttatttttt
    39001 tcaaatcata ctaactaatc tatactgtca aggtttaatg tgactatttt gaatagtcag
    39061 caaactatcc tatgcgttca gctgctaact tcaccaattt tcctgtcctt gcatttcatc
    39121 agttagctac tcataagcct caaacagagt ataagtcctc tttgcataac gtcttagtgt
    39181 tataaaatat tttgaccgac agccttttca accatggctt gtatgcgtga caggcctatc
    39241 ccttgcgctc cttgatgagt tggtaatggt aggactgctg gtagaacttg attgtcatag
    39301 tgagtgaggg cttctggaat agctgcagca atatcttctg tgatataaat aataccaaag
    39361 tcttccattg ctagttgacg caactggtta atagcgtctt gtggttttat tactggaaaa
    39421 gtttgaaacc caatcatctg aaaaggtaga ataacatctc tgttaccaat taccccgact
    39481 ttatacaatg ttttggtcat gctattggtc tcatcctttc tatgacacgt tctttgggta
    39541 aatcattagc taaagcagcc gctaaaagcc gtaggttttt tacttcaaac gatttagcga
    39601 gcaaaaagcg agcaagcaca taaggtccat cgacttgata tttggccttc gcaaataaat
    39661 ggtaaaggca ttcatcaaca aggtattcta actcagtcgt ttgaagagtg ccttggcgaa
    39721 gtttctctga ataaggtttt agggctgtca tatagctatc aggtgttaca ttttcaaacc
    39781 acgtcatcag atccttatca tcttcaagtg tgataaatgt tttacttggc ctacttgctt
    39841 catcagataa taactgcatc atgaaactta ttggtttatt ttgcgacttg gcccgtctga
    39901 cggtaatcag attatacaaa tcaatcacaa taagaacagc ttgttggaaa acagggtcct
    39961 ctaatctttg tgctatttgt ttcaacgcct taaaataagc taagtcagta ccaatttcta
    40021 agacgcgtat gtcttgataa tcttgatatt cggcccaaat ggactggatt tctgttacta
    40081 cctcttttgg aaactcatca gaagtcatcg tcctaatcaa atgttccaaa gccaccagag
    40141 gcttgtcacc aattggtagt aataagtgac tcagatctgc ttgactagct ttagctttta
    40201 acaacacttt gacattatga taggtgtaac gcaaggtaaa taattgtact atgtcaggtt
    40261 gaggggtttc tgcaaaagcc cagcgatagg tcttggttag ctcagccatt aagatagatt
    40321 ctagccgatc caaatcgttg agatcgtcaa cagttaggtg atagactgac tggtgcaaca
    40381 gtcgagctaa ggttgttgta ttgggagcct gcaatagctt atcaaattgc tctttagtca
    40441 ataactcttt ttctttgaca ctgatagtag tgtttaattc tagaaatgtt ggcatcgcta
    40501 gtcaaacctc ctatatctct gaaaaaagca tatcaatgat gcgggagctt tcttctttaa
    40561 gaactgattc taaaaggtaa cggtataaat aattgtcatc gacttggtct aaactgacta
    40621 aaaatcctgc ttcctgagga attagctctt gattatagct taattgagga aacgctaatc
    40681 tcagctcagc acaatcataa gaactgaact tttgccctgt tttttcgcca aaagtaactt
    40741 gcaatggctg ttctggatat ttagacaaga cttgcttcaa aaaagccaat tcttcttcct
    40801 tagaaaagtt cgtcatcttc tccaaagaag cttcaaatag ctcctttata ctgtcttgtt
    40861 ttaatgctag tagagcttgt ctttcttgat ttttgagttg ctgctgcgca acctgaaatt
    40921 gctgttcaag agcttttaac tctttttgac gctttgcttt taaatcgtgt agtccttgct
    40981 gttgacgctc tttaaagtca gtatcaagac tatctgtcgc tatctttagg cactgttgac
    41041 cttcttgatg tgctttttca agaacgtttt gtcttaactg tgttatatca ttcacctaat
    41101 ttcccccttt tgatagtgtt agtggtgtca ccgtttttta aaatctagat aaggaccgtt
    41161 accttatcca attttattta agagaataaa ggagacgaca aaggcaagaa tagcataggt
    41221 ttcaaccata gctgctaaaa tgacaccctt cataaaatct ttagggcgct tagccaagat
    41281 ttgcatacca gctacagaaa cattgccttg gtgcttggcc gaaaaataac caacaatagc
    41341 aattggaaga gataccaaaa agtaagctaa tccttggtta actgaaagtt ctggtgtcag
    41401 tttcatccaa attaaaatac caatagcaaa gccgtagatt ccttgactac cgggtaacag
    41461 ttgcaagata agcgcagacg taaatttttc gggttcttct tttaagagcg cagctgccgc
    41521 ttgaccacct ttaccgacac cataagctga gcccatgcca ctaagagcta cggctaaaac
    41581 aattcctaag gctgcgaaga aaacgccacc atgtgctgta aaataatgtg ctaaatgttc
    41641 catgttaatt gtcctccaaa tctgtttctt cattgacatt gacataatta tcagctaact
    41701 ttaaaggatt gaaagctttt cctccacctt cataaaattt tccaaaaaac tctacgaaaa
    41761 taagacgagc accatgcaca tatcctgaaa gcattgataa gaaaatattg atcgcatgca
    41821 aaagaataaa aataaagata cctactgtaa agcgcgtgac tggtggaaaa atcccaacaa
    41881 tcatgttaaa agccgctcca atactagctc cagaaagccc taatgccatt agacgagtaa
    41941 agctaaccaa atcacttaag taagagctaa tgccatataa attatataat ccactaccta
    42001 gacctaaaag gcttttgctt tttagtaaag aaacaaccaa aatcccaaag gcattgccca
    42061 atgcaagcca cttaccaata accgataagt aagcaaggcc agatacattc ttaccaagaa
    42121 taaataacag caggcctaat aaaataaaag tccaagctag acttgacgta taggccgtag
    42181 catatgcttt catccttact tgttgccatg ctcctaacaa aagcccaaat ataagtgtaa
    42241 caaacccaaa tagcaaagaa acaaccaaaa tagtaatcac atccgtttta gttgataata
    42301 atgccacagg taagtcaaaa ccaaagaaag aaccgtaaat aagcccccat agggctactg
    42361 aaatagctaa aatattaaag aaagtcacta accgtttact ggttttttgg agattaaaaa
    42421 agaccaatgc agctagtgtc acagcatata gcaacaaacc atagcccaaa tcagctacca
    42481 tcatgccaaa aaaagtaagg tataaaggag ctaaaaaagg tgtcggatct ttttcttgat
    42541 attttggcaa agcgtacatt tctgtaacca attcaaacgg tgcaatgtag cggtgattac
    42601 gtaacttaat gggaacatct tcccaatcgt ctggcgtgac atcgtaacta tccagataaa
    42661 acatatcacc tagtgtctca gtcattagcc cttttaattg gttaaccgaa tcaacttcta
    42721 tccacccttc taaggctatt agatgtcttg taccgagtaa ttgcttttta gtttgctgcc
    42781 gttgatactg actaaggaca tagtctattt caacctgtaa ctgtgccagt atcttttgag
    42841 actgcctaag ctcttttagt agactatctt tttcagctag ccaattcgtt agtaactctt
    42901 tgtttatacg aagttgttct gatggcagta gctgttcttt atataataag ggtttaaact
    42961 gatatttctg taaatgaatc gtatcttgtg cttgccaaaa taagacaagg ccgtactcaa
    43021 attctgtatg gtatacttcc tcaataaaaa gacctttgta ctgctttagc tgatgataaa
    43081 aatgatcatt tgctgtacta ggaatcgttc caactcttgc cgacaaaaaa tgaaattgcg
    43141 ctaagtcctg aggcaaaaca gtcaaggaac gccacttttc taactcctga cagtattctg
    43201 ttagctggtc tattttgttt tgcagctgct ctagtcgctc tatcttttgt gacatcattt
    43261 tcaaagtcgt ttgagctgct tgttgtcgat ggctttcttc gaactgttta aacgaaagag
    43321 atggcgtttt ttgtctcaag gctgttaact ttcctattgg tggtaaaaac gctgataagc
    43381 tagcaaggcc attttctaac tcttgttggc tttgtaaaag gtattgtaaa gcttcatcat
    43441 ctagtagagg tttttgatgc gtcagatcgt attggacgat ttgtggcaac ttgacgttgc
    43501 ctttgttaaa agcatcttgc caatgtttta gttgcttcat gtcacgaact tcaactaatt
    43561 gagattgttg aagtgttttt aaaacaagat caagataatc tttttcaaaa accattgcca
    43621 gctttttcat ttgactaatg gccatatgtc tccaccacct tatccactaa ctccctaaca
    43681 acggttagct tatgctcttc taaaatggca tgaagggcta gctgttgcgt cgctaacctc
    43741 ttttttgaag ctttttgttc ttgacgatta gcttcaaaaa acacctcacg tttagcttct
    43801 aatagtagct gagtttcttg ttcgtactca aggaacagct gctttaactc ttcttctttt
    43861 ttgtcagcta gagctttttt cttagcatcg taactgtcat aaattgttct agcctcttgt
    43921 tcgatactat tcattagtga caatagggta ttcatcacat atcaactcct tatctttatc
    43981 tattgctaat tctttgactc actaggtact taaaaacaaa gctacaagaa aggctacttt
    44041 tggggggtta atcaaccagc gaatataagc tagagctaaa tctctaacct atctactaac
    44101 agcttttttg agataggata atagcttaat taaacgaaca gcatctgtaa gttaagcgct
    44161 ttcaattcta tccataaaaa caatggctta gttcagaaaa aggttagcta aaaacctgtc
    44221 aaagcagtaa gatgacacag aactctaaag ctttgtattg ctgtctttca tgtgttatct
    44281 tatacttctt taggcattta gtaaccttga tctcgttgac ggtaaggaac ctttaccagc
    44341 caatagccaa gccaatgtga taacagtata actgctatcg tgttaaaagt cctgtcaaaa
    44401 agatgtttat tagtttctcg cttgtaattc ttgttttgtt actaaacggt aatttttaaa
    44461 gacagaacct ccaatataac ccacaattaa gctgataata atacatccaa gggctgttat
    44521 caacacttta gcgacaggat tataggcaaa catcaccgca aaaccggcaa tcggagtagc
    44581 tgtccctggc gtatcattaa ccaatttcat tagggcgatc aaaacaccac atgcaccacc
    44641 accaacaaaa ttagtcacat aaatcggaat gggattggct gacgtcacat ctgcctgagt
    44701 caacggttca atagcaaaag caatattgtc ttttctttca cccaatttta atcggtaaaa
    44761 aagaacacca ttcataaaag aagagccaaa gacagataag gcacctatag ccatcggaat
    44821 acctgttaga ccaagcatgg ctgtcaaagc cattgatgat agcggagctg ttgctacaac
    44881 aacaatcgta ccgcctagta tcattcccat gataataggg ttgctattag cacttgaggt
    44941 caggatgtct ccaatagtca ataaagtact attgatcact ggcgtaatta actgcgccaa
    45001 gaaacgagtt aatggtgcac cgacaataat aatcgagatt aaatcaagcc caccaggaat
    45061 atttttttcc atccacttga ttaaaaaaga taccacatac ccagccacaa aacctgggat
    45121 aatacctgtt cctgaaactg acaaaccaat caaaacggca taacctggag acacaccaat
    45181 tgcaatggca accaagatag cagcagctac ccctgataat gagccatttg ctccgcctac
    45241 ttcacttaga aactgaaagc ctaaaacctt accaaaaaaa gaatcttgaa aggcttcaac
    45301 taaaaaagag gcacaagctg ccgaagccaa agctcccatt gccttggcac catgaggagc
    45361 cttatagtta aacaagctaa aaatagctaa aacaagaatc aaaagacttg ttccaataat
    45421 aatatccata atctattcca ccaatctatc tcattacata agacactata actgcttcac
    45481 tctggcaacg gcttcgactt caatcaaagc ttgcaaagga agcgccgaca cttgaaccgc
    45541 tgtccgaaca gggtaaggct cttcaaacaa atcagtcatg acatgattta atatttccac
    45601 attggtcaca tctgttaaat acacatttag cttatagata tgattcaagt ccaacttttg
    45661 ctctgccaaa atagattgta aattaacaaa aacctggcga cactgtgcct caaaaccatc
    45721 tgacaattga cctgtcactg gattaagggg taattggcct gcggtgtata gaaaatgtcc
    45781 ttcaatcgta taagttgaat aagggcccat tggttctggg tagctcttca tatacgaacc
    45841 tcctcattga taatatagtt aaattttaca ggaaaccgca ttcacagtca ataataaatt
    45901 ctctttttga taaaaaatta ttattaaggt gattggcaat tgttttttag tctaaaatgt
    45961 attactatat ttgtaaataa gaagatagat ataggaagtt tgacatggat aaagaaacgc
    46021 taaactactg gaaaacggtt atcacatttc ttcacgatgt cttaggtgat aactatgaaa
    46081 ttattttaca tgtgattgat aaaaatgata tctatattgg agaactcgtt aatagtcata
    46141 tcagtggacg gtctaaacag tctcctctca ccacctttgc tcttgatttg attaccaata
    46201 aagtctataa ggaaaaagat tttgtgacca attacaaagc aatcgttagt cctcagcaca
    46261 aagaagttcg gggatctact ttttttatta aagataaaaa gggtaatctc gagggaatgc
    46321 tatgtattaa cttagatatt tcagcctatc aaggagtagc tagggacctc ttaaaacttg
    46381 tcaatctcaa tttagaacat ttcatcccaa ctgctaaaga acctaaaaca gtcacacccc
    46441 agccagaaga agctgttgaa attttaacct ctaacatcca agatattatt ggtcaaatta
    46501 ttgatccctc gttactgaga cacaatgtac atcttagcca agatgtcaaa atagacattg
    46561 ttgccaagct ttatgaaaaa ggagtctttc aactaaaagg agccgtctca aaagtcgctg
    46621 atattctatg tatttccgaa ccaagtgttt accgctacct taaaaaaatt gaagccgatc
    46681 aataaccaaa tcaccataaa acgccagtta aaagtatttc agataagcat cacaatctct
    46741 gatataccga tgactgacgt ttttttactc gatatgcctt tatggcaaga aaaggctact
    46801 agtcattaac cttcagctat gcttagaggt acgcctgtcg cagcttgaac ctcatcaaaa
    46861 gtaaaccctt cactgatttc aattacttgg ataccatctg gcgttacttt aaacacaccc
    46921 atttctgtga taataaggtc aaccacacct tttgctgtta aaggtaaggt acattctttt
    46981 aggagcttat gctttccttt attggtatgc tccatagcta cgatgacttt tttagcacca
    47041 actaataaat ccatcgctcc tcccatacca ggaaccattt tgcctggaat caggtaattg
    47101 gcgatatctc cattttctgc aatttctaaa gcacccaaga cggtcaagtc aacatgacca
    47161 ccacgtataa tgccaaaaga atctgcacta ttaaagaaag cggctcctgg ataaaccgtc
    47221 acaggctgtc ctcctgcatt aacgatagtc gaattcggat catctgactt aggacctagt
    47281 ccaataaacc cattttcaga ttgaaaatac actgtcattt cttcaggcac aaaatttgct
    47341 actttggttg gtagaccaat acctaaattt accaaagtac catcttctaa ttctttggct
    47401 acacgctttg caatacgatt ttgaatctct tctttactta atgcaaccgc cataactata
    47461 ctccttcttt aacaatgtaa tctacaaaaa tgtgtggtgt atgaacgcat tctggttgta
    47521 tggtgccgac tggtactatt tctcgcgcct gaacaattgt tgtttttgca caagctgcca
    47581 tcaattgatt aaaattattt tcagaaccac tatactgtaa atttcccatt tcatcagctt
    47641 tattagcaaa tatcaaggcg acatctgctt caaatgggta ttctaagaga taggtttttc
    47701 ccttgatggt ttttgtttcc ttgccttctg ccactaaggt tcctacccct gttggcgtgt
    47761 aaaagccacc aatgccataa gctccgatgc gaattttttc ggcgaaggtt ccttgaggaa
    47821 tgagctcaat cgtcgtttca ccggcagtca tttggcgccc agcttcttta tttaatccaa
    47881 tatgtgttgc ataaatggtt ttgaattgat gattagccac catttttcca acaccgcgat
    47941 caacaaaacc agcatcatta cagatcaaga ttaagtcttt tgtgcctttg tcaaccagtg
    48001 catcaattaa cgcttctggt gttccattag ccataaaacc accgaccata atcgtgtcac
    48061 catctttaat atgactgata gcttctgcta ttgctattct tttattctct ttcatacggt
    48121 taccttctat cttgttacga tgatactttg accttggcca ccaccaatac aaagcgttgc
    48181 taagccatgt ctcacatcac gcttagccat ttctgctaat aaggtgacta aaatacgagc
    48241 acctgatgct ccaatcggat gacccaaagc aatagctcct ccattgacat taactttttc
    48301 attgtcaaaa ccaaggtctc gtgaaaccgc taaagcctga gcagcaaaag cttcgtttgc
    48361 ttcaatcaaa tcaatgtcat caattgtcag ctgagccttt gcaagagcct ttttcgtagc
    48421 aggtattggt ccgcagccca taatacttgg gtctacacct gcacttgcat aactagtgat
    48481 tttagctaaa atagggagcc ctaattcttc agctttttct ttactcatca ataaaattgc
    48541 tgctgctcca tcattgattc ctgaagcatt accagcagtt actgtcccct catctttgat
    48601 aaaagcaggg cgtaactttg ctaacttatc cactgtcgtt ccaaatttag ggtattcatc
    48661 ttgatcaacg agtaaaggtt cacctttacg ctgaggaata gtgacaggtg caatctcttc
    48721 tttgaaacga cctttttcta tggcaagttg ggctttacgt tggctatcag ctgcaaaggc
    48781 atcttgttct tctctggtca gtccatactg ttgcacaata ttttcggctg ttatacccat
    48841 gtgataacct gcaaaagcat cactcaaccc atctttaagc atggtatcta ctactttact
    48901 atctcccata cgagatcccc aacgttggcc ttgtaaaacg taaggtgctt gactcatgtt
    48961 ttcggtacca ccgactaaaa caatatcagc gttgcccgtt tgaatctttt gagcacctaa
    49021 ctcaactgct tttaagccag aaccacagac catatcaatc gtaaaagcag gggtatcata
    49081 agaaagcccc gcatttagcg ctacttgccg agcaacattt tgacccagac ctgcatgtaa
    49141 cacattccca aagatcactt catcaatggc atcactttta agaccggtat cagctaaaat
    49201 ttttgtaaca actgtcaccc ccaaatctac ggctgataaa gatttaaaga ctcctccaaa
    49261 atttcctatc ggggtacgat aagcagatgt gatcaccact tctttagtca tagaaacttc
    49321 tcctttttca t
//
LOCUS       DAUCXI010000010        48234 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.010, whole genome shotgun sequence.
ACCESSION   DAUCXI010000010 DAUCXI010000000
VERSION     DAUCXI010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48234
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.010"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..322
                     /locus_tag="VGY43_000574"
     CDS             <1..322
                     /locus_tag="VGY43_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ4301788.1"
                     /translation="NKDKKKISAVLEKVGLSSDYLNQKIYELSGGQAQRVAIARMLMK
                     PRKIILADEPTGALDGEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDFIIDMKDI
                     GSKK"
     gene            319..810
                     /locus_tag="VGY43_000575"
     CDS             319..810
                     /locus_tag="VGY43_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301789.1"
                     /translation="MKKKIYIGLIVIVGVFVVFLSGKQITQKETSNKPEVTLTVYTIS
                     SSDTQKWSKVKQFETKEAIYLVKVKETTSSEEVFSNIIADGMAVGFGVSEEDVKQFND
                     NLCSPVEDAKNNKLIGIEFINFSSVDKGFVVANFDYGKKAFNSQKTENKKLYKKLYEA
                     YKG"
     gene            1014..1544
                     /locus_tag="VGY43_000576"
     CDS             1014..1544
                     /locus_tag="VGY43_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEQ4301790.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFLTRLFAK"
     gene            1593..2180
                     /locus_tag="VGY43_000577"
     CDS             1593..2180
                     /locus_tag="VGY43_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEQ4301791.1"
                     /translation="MKHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            2333..3070
                     /locus_tag="VGY43_000578"
     CDS             2333..3070
                     /locus_tag="VGY43_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ4301792.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTEGGRRLYT
                     DSDLEQLRMICFLRDLGFSIEQIRKVLAEENAAQVLELLLVDHIATAKEDLAAKEQQV
                     DIAVKILDRLRKQDPQSLDFLMDISLSMKNQKAWKKLQWKMGISIFLAIVSYVGLILL
                     SSYLQKFWLVYVAMGLFLPGFSWLVIYFRKQFIYLCPHCHQKFEPSFNEFALAGHTPR
                     TRKLTCSHCHQKSYCLELAKEDTVSRR"
     gene            complement(3127..3426)
                     /locus_tag="VGY43_000579"
     CDS             complement(3127..3426)
                     /locus_tag="VGY43_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEQ4301793.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDETTKKTLGAFAGKLPF"
     gene            complement(3619..3993)
                     /locus_tag="VGY43_000580"
     CDS             complement(3619..3993)
                     /locus_tag="VGY43_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4301794.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLENKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            4163..4384
                     /locus_tag="VGY43_000581"
     CDS             4163..4384
                     /locus_tag="VGY43_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4301795.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(4464..6746)
                     /locus_tag="VGY43_000582"
     CDS             complement(4464..6746)
                     /locus_tag="VGY43_000582"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEQ4301796.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKL
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRNKITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIVNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRAFKAALFKGKANQALVDILLEEDLLINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFRENSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(6768..7427)
                     /locus_tag="VGY43_000583"
     CDS             complement(6768..7427)
                     /locus_tag="VGY43_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEQ4301797.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
     gene            7593..8789
                     /locus_tag="VGY43_000584"
     CDS             7593..8789
                     /locus_tag="VGY43_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ4301798.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPACKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTAVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVVS"
     gene            9261..10109
                     /locus_tag="VGY43_000585"
     CDS             9261..10109
                     /locus_tag="VGY43_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEQ4301799.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKVSYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(10444..11340)
                     /locus_tag="VGY43_000586"
     CDS             complement(10444..11340)
                     /locus_tag="VGY43_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEQ4301800.1"
                     /translation="MNEMLILRLIQALLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYLGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            11638..12390
                     /locus_tag="VGY43_000587"
     CDS             11638..12390
                     /locus_tag="VGY43_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEQ4301801.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDTLFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            12375..13324
                     /locus_tag="VGY43_000588"
                     /pseudo
     CDS             12375..13324
                     /locus_tag="VGY43_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
     gene            complement(13504..15831)
                     /gene="pflB"
                     /locus_tag="VGY43_000589"
     CDS             complement(13504..15831)
                     /gene="pflB"
                     /locus_tag="VGY43_000589"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEQ4301802.1"
                     /translation="MATVKTNTDVFEKAWESFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            16041..17135
                     /gene="dinB"
                     /locus_tag="VGY43_000590"
     CDS             16041..17135
                     /gene="dinB"
                     /locus_tag="VGY43_000590"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEQ4301803.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVVGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDLVEPMSIDEAYLDVTDNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGVTMTNLEDKVADISLDL"
     gene            complement(17228..17710)
                     /locus_tag="VGY43_000591"
     CDS             complement(17228..17710)
                     /locus_tag="VGY43_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301804.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVLSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSVLNVLAIIAIIVFCAQNLSKLKQGLTVSYI
                     PYILGLILSVIGLVNQFTTTLSMVGTILILIQAALYGFAFYKAKTLNEKGDDTDQAML
                     "
     gene            complement(17801..20254)
                     /locus_tag="VGY43_000592"
     CDS             complement(17801..20254)
                     /locus_tag="VGY43_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEQ4301805.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFAFQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMTDALAENLGIESDSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNANPTENSQSDNDDFRLTPENYSTI
                     DSMIGLTESDIALFFQKKS"
     gene            complement(20312..20905)
                     /gene="lepB"
                     /locus_tag="VGY43_000593"
     CDS             complement(20312..20905)
                     /gene="lepB"
                     /locus_tag="VGY43_000593"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ4301806.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(20916..21818)
                     /locus_tag="VGY43_000594"
     CDS             complement(20916..21818)
                     /locus_tag="VGY43_000594"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEQ4301807.1"
                     /translation="MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHPFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            21975..22283
                     /locus_tag="VGY43_000595"
     CDS             21975..22283
                     /locus_tag="VGY43_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301808.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            22286..22831
                     /locus_tag="VGY43_000596"
     CDS             22286..22831
                     /locus_tag="VGY43_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEQ4301809.1"
                     /translation="MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSLLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLARL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            22980..25319
                     /locus_tag="VGY43_000597"
     CDS             22980..25319
                     /locus_tag="VGY43_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEQ4301810.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSADLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADERHEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFTLVRVQEEQ
                     KVKSKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG"
     gene            25323..25823
                     /locus_tag="VGY43_000598"
     CDS             25323..25823
                     /locus_tag="VGY43_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEQ4301811.1"
                     /translation="MESYEHFYAKLSQPFRKSPQLIILLNVLLKIITGVMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDFPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSVLLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            25904..26218
                     /gene="trxA"
                     /locus_tag="VGY43_000599"
     CDS             25904..26218
                     /gene="trxA"
                     /locus_tag="VGY43_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEQ4301812.1"
                     /translation="MALEVTDATFVEETKEGLVLIDFWATWCGPCRMQTPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(26270..26857)
                     /locus_tag="VGY43_000600"
     CDS             complement(26270..26857)
                     /locus_tag="VGY43_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4301813.1"
                     /translation="MEIGQQIIRYRKQQALSQEELAEKVYVSRQSISNWENDKTYPDI
                     HSLLLLSQIFQVSLDQLIKRDIEKMKYTITQVDKKNFKRDTKVMVTLMILLMISSYPL
                     VYFLEWLGLGIFVLLSIITMTYANRVERFKKKYDVQPYKEILAVSSGKLLDEIEKREE
                     RAKLPYQNPLIVTVFFLITVAIAFASRFMFTWLFH"
     gene            complement(27034..28158)
                     /gene="mutY"
                     /locus_tag="VGY43_000601"
     CDS             complement(27034..28158)
                     /gene="mutY"
                     /locus_tag="VGY43_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEQ4301814.1"
                     /translation="MWDNETIASFRRTLLGWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFSLYPFATPQKKMLETYLKQKNT"
     gene            28356..28649
                     /locus_tag="VGY43_000602"
     CDS             28356..28649
                     /locus_tag="VGY43_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301815.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            28822..29112
                     /locus_tag="VGY43_000603"
     CDS             28822..29112
                     /locus_tag="VGY43_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEQ4301816.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            29134..29625
                     /locus_tag="VGY43_000604"
     CDS             29134..29625
                     /locus_tag="VGY43_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ4301817.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            29790..30029
                     /locus_tag="VGY43_000605"
     CDS             29790..30029
                     /locus_tag="VGY43_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEQ4301818.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(30162..30818)
                     /locus_tag="VGY43_000606"
     CDS             complement(30162..30818)
                     /locus_tag="VGY43_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEQ4301819.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQRAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGVSLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(30951..31895)
                     /locus_tag="VGY43_000607"
     CDS             complement(30951..31895)
                     /locus_tag="VGY43_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEQ4301820.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
     gene            32098..34926
                     /gene="uvrA"
                     /locus_tag="VGY43_000608"
     CDS             32098..34926
                     /gene="uvrA"
                     /locus_tag="VGY43_000608"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEQ4301821.1"
                     /translation="MQNKIIIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPVVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGDIFDVTGVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLKEGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
     gene            35042..36115
                     /locus_tag="VGY43_000609"
     CDS             35042..36115
                     /locus_tag="VGY43_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ4301822.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLGADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRLIKDVSEIETIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIAASGYRSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIAKASAGMTYSDFDGIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHENPFLGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITKTGCQVLTLAPKELIVL"
     gene            36150..36611
                     /locus_tag="VGY43_000610"
     CDS             36150..36611
                     /locus_tag="VGY43_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEQ4301823.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ"
     gene            36707..37264
                     /gene="efp"
                     /locus_tag="VGY43_000611"
     CDS             36707..37264
                     /gene="efp"
                     /locus_tag="VGY43_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEQ4301824.1"
                     /translation="MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            37310..37699
                     /locus_tag="VGY43_000612"
     CDS             37310..37699
                     /locus_tag="VGY43_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ4301825.1"
                     /translation="MTTEYIGEIVISPRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTEEDGSVTADIYVYLQYGVKVPTVSMNIQKTVKSAVYDMAEVPISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            37692..38144
                     /gene="nusB"
                     /locus_tag="VGY43_000613"
     CDS             37692..38144
                     /gene="nusB"
                     /locus_tag="VGY43_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEQ4301826.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS"
     gene            complement(38285..39250)
                     /locus_tag="VGY43_000614"
     CDS             complement(38285..39250)
                     /locus_tag="VGY43_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ4301827.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEILKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(39255..40694)
                     /locus_tag="VGY43_000615"
     CDS             complement(39255..40694)
                     /locus_tag="VGY43_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEQ4301828.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGRYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRNANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFIADLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGA
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYNYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQIPQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTQGQTGIQVVEGQAFGHYYEMRY"
     gene            40936..42819
                     /locus_tag="VGY43_000616"
     CDS             40936..42819
                     /locus_tag="VGY43_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ4301829.1"
                     /translation="MDNRQIATEVIEALGGRENVRSVAHCATRLRVMVHDEGKIDKEK
                     AEAIDKVKGAFFNSGQYQMIFGTGTVNNIYGEVVALGLPTSSTSEQKAEAGKQGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSILGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSPKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGLAFAIA
                     YTWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLAAVSDPVFSSGAMGQ
                     GLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            42996..45974
                     /locus_tag="VGY43_000617"
     CDS             42996..45974
                     /locus_tag="VGY43_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEQ4301830.1"
                     /translation="MVYQLGSHDLVPKIRSVQMDKHLLVKRTLGCVCAATLMGAALAT
                     HHDSLNTVKAEEKTVQVQKELSSIDSLHYLSENSKKEFKEELSKEKVPEKVKEILAKA
                     QQADKQAQELTKMKIPEKIPMKPLHGPLYGGYFRTWHDKTSDPTEKDKVNSMGELPKE
                     VDLAFIFHDWTKDYSLFWKELATKHVPKLNKQGTRVIRTIPWRFLTGGDNSGIAEDTS
                     KYPNTPEGNKALAKAIVDEYVYKYNLDGLDVDVEHDSIPKVDKKEDTAGVERSIQVFE
                     EIGKLIGPKGADKSRLFIMDSTYMADKNPLIERGAPYINLLLVQVYGSQGEKGGWEPV
                     SNRPEKTMEERWQGYSKYIRPEQYMIGFSFYEERAGSGNLWYDINVEDESNPNIGKEI
                     KGTRAERYAKWQPKTGGVKGGIFSYAVDRDGVAHPKKNGYKNPKLDNIVTSDYSVSKA
                     LKTVMLKDKSYDLIDEKDFPDKALREAVMAQVGTRKGDLERFNGTLRLDNPAIQSLEG
                     LNKFKKLAQLDLIGLSRITKLDRSVLPANMKPGKDTLETVLETYKKDNKEEPATIPPV
                     SLKVSGLTGLKELDLSGFDRETLAGLDAATLTSLEKVDISGNKLDLAPGTENRQIFDT
                     MLSTVSNHAGSNEQTVKFDKQKPTGHYPDTYGKTSLRLPVAEGNIDLQSQLLFGTVTN
                     QGTLINSEADYKAYQNHKIAGRSFVDSNYHYNNFKVSYENYTVKVTDSTLGTTTDKTL
                     ATDKEETYKVDFFSPADKTKAVHTAKVIVGDEKTMMVNLAAGATVIKSENDENAKKVF
                     NGIMEYNPLSFNNKSSIIFEMKDPSLAKYWRLFNDSSKGKDDYIKEAKLEVFTGQLNA
                     EADVKTSLEKSDDWQTVSTYSGQEQVFSHALDNISAKYWRITVDNKKNQYGCVSLPEL
                     QILGYPLPNADTIMKTVTAAKELSQQKDKFSQKMLDELKIKEMALETSLNSKIFDVTA
                     INANAGVLKDCIEKRQLLKK"
     gene            46238..47122
                     /locus_tag="VGY43_000618"
     CDS             46238..47122
                     /locus_tag="VGY43_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEQ4301831.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFPTTTPEETIAQT
                     IAYFKTFEADLAGMAIGSFGPIDIDPSSETYGYITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     LHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQAIVFGGGVMAQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVVDN
                     GSATLGNFALAKLAAQGK"
     gene            47217..48170
                     /gene="manA"
                     /locus_tag="VGY43_000619"
     CDS             47217..48170
                     /gene="manA"
                     /locus_tag="VGY43_000619"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEQ4301832.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYAQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GHEHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATMVLDNMVATTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
BASE COUNT        14762 a         8488 c        10121 g        14863 t
ORIGIN      
        1 caataaagac aaaaaaaaaa tatctgctgt acttgaaaaa gtagggctct ctagtgacta
       61 tttaaatcaa aaaatatatg aattgtctgg agggcaggct cagcgtgtag ctattgcaag
      121 aatgttaatg aagccacgta aaataatttt agcagatgag ccaacaggag ctttggatgg
      181 tgaaattgga aaagaaatta ttaatttgtt gttgagcgaa acagccgaaa ataaatacgt
      241 tattatagca actcatgatc cagctgtata taataaggtt gattttataa ttgatatgaa
      301 agatataggg agtaagaaat gaaaaagaaa atttatattg gcttgattgt cattgttgga
      361 gtttttgtag tgttcttgtc tggaaaacaa atcacacaaa aagaaacttc aaataagcct
      421 gaggtgaccc taacagttta taccatctcc tctagtgata cccaaaaatg gagtaaagta
      481 aagcagtttg aaacgaaaga agcaatatac ctagtaaagg taaaagaaac tacctcttca
      541 gaagaagtct tttcaaacat cattgcagat ggaatggcag ttggttttgg agttagtgaa
      601 gaagacgtta aacagtttaa cgataattta tgtagcccgg tagaagatgc taagaataat
      661 aaattaattg gaatagaatt catcaatttt tctagtgttg ataaggggtt tgtggttgca
      721 aattttgact acggcaaaaa agcgtttaat tctcagaaaa cagaaaataa aaaattatat
      781 aaaaagctct atgaagcgta taaaggatag ctatttatag tttcttgaga gtgataccac
      841 ttctgaataa taaatgaact aacttggcat accgttttct attcatctaa caatgttttc
      901 aagaaataat tgatgccttt agcacggctg aaatgaggtc aaattgacag aatactccta
      961 ttatggtact atttttaata agaatattca gtgatagtga taaagaggaa aatatgggaa
     1021 ttgaaaagac agttagtgaa ctagctgata ttttgggagt gagtcgtcag gccgtcaata
     1081 atcgtgttaa gtctttaccc gaagaagatc ttgacaaaaa tgaaaaaggc gttactgtgg
     1141 ttaagcgcag tggtcttgtt aagctggaag agatctataa aaaaacaatt tttgacgatg
     1201 agcctatcag tgaagaaacg aaacaacgtg agcttttaga gattcttgtg gatgagaaga
     1261 acactgaaat cacgcgcctt tatgagcaac tcaaagccaa agatgctcaa cttgcctcaa
     1321 aagatgagca aatgcgtgtt aaagacgtgc agatcgctga aaaagataaa caattggatc
     1381 agcagcaaca attaactgct aaagccatgg ctgataaaga aaccctaaaa ctagaattgg
     1441 aagaagctaa agcagaagcc aaccaagctc gcttacaagt cgaagaagtt caggctgaag
     1501 ttggccctaa aaaaggcttt ttaacccgct tgtttgcgaa ataatcacaa aaaatgacga
     1561 aggccctatc agggtctttt ttggaggaaa acatgaaaca cttagatact tatattgcct
     1621 ttgatttaga atttaacact gtcaatgacg ttagtcatgt cattcaagta tcagcagtca
     1681 aatatgacca ccataaagaa gttgacagct ttgacaccta tgtttacaca gatgttccct
     1741 tacagagctt tatcaatggc ctaacaggaa tcacatctga caagattgct gcggcaccaa
     1801 aagtagagga ggttatggct gcgtttaaaa attttgtggg agagttacca ctgattggtt
     1861 ataatgctca aaaatctgac ctgcctattc tagctgaaaa tggcttagat ttaagggacc
     1921 aataccagat tgacctcttt gatgaagctt acgatagacg tagcgcagac ttaaatggga
     1981 ttgctaacct tcgtctgcaa acagtggcaa cctttttagg cattaagggt cgaggtcata
     2041 atagcttaga agatgccaga atgacagcag caatctataa gtctttttta gaaacagata
     2101 caaacaaagc atatctcagc cagcaagaag aggtaaccac agataaccct ttcgcagctt
     2161 tgggagactt ttttgactaa gggctctgct atttctaaaa aataacaaaa attcctaggg
     2221 ttagctcttg cttgtaacgc taggtcatgt gataagatag gggcatatca agagggagtc
     2281 gagtgcacac gaatcgtttt tgatcactaa atgatagaaa gaaggtgtgg aaatgtctca
     2341 attctattcg actggagaat tggccaactt agctggcgtt tctattcgaa ctgtccaata
     2401 ctatgatcaa cgtgggattt tgattccgac agctttgaca gaaggtggac ggcgactcta
     2461 tacggattct gatttagaac aattacgcat gatttgcttt ctgcgcgatt tgggattttc
     2521 cattgagcag attcgcaaag tcttagcaga ggaaaatgca gcccaggtgc tggaattgct
     2581 tctagttgat catattgcga ctgccaagga agacttggcc gcaaaagagc aacaagttga
     2641 catagctgtc aagatacttg acagacttcg aaaacaagac ccccagtcac tagattttct
     2701 gatggacatt tcgcttagca tgaaaaatca aaaagcttgg aaaaaattac aatggaagat
     2761 gggtatcagt atatttttag ccattgtttc atatgtagga cttattttac tatctagtta
     2821 tctgcaaaaa ttttggttag tttatgttgc tatgggacta tttctaccag gtttcagttg
     2881 gttggtaatt tattttagga agcaatttat ttatctctgt ccccattgtc atcagaaatt
     2941 tgaacctagc tttaatgaat ttgcccttgc aggccataca ccacgaacca gaaagttaac
     3001 ctgctcccat tgccatcaaa aatcgtattg cttggaactg gcaaaagagg acactgtctc
     3061 aagaagataa gcactaactc ataaaaaaac tagcctgaga tccttctcaa gctagttttt
     3121 gtttttttag aatggtaatt taccagcaaa agcgcctaat gttttcttag ttgtttcatc
     3181 aatttgcgta agggcatcat taatggcttg agtggtcatg tcttgaagcg tttctacatc
     3241 ttcaggatct acaacagctt ctttgaagtc aatcccaacc aattttttat cacccgtgaa
     3301 agtggcagtg acaaggtctt gagctgattt tccagtaaat tgcatagcag ccaaatctgc
     3361 ttgtttttgt tccatttgtt tctgaagctt ttgtgcctgc ttcatcatat tctgcatatt
     3421 catcataaga ctatactctc cttaatttaa tactaactat tataacatat aaaaagaggc
     3481 aataaaaaca atgtcagtta gtagactagc ctgtatcagt aagaaagtcg ctatggataa
     3541 gatggattag cagcaagggt ctggctaatg acagaataag tctagaaatg aactattttt
     3601 gtcatagact agtccgactt agtggttatc taattcacga tcttctttag cttgttgttc
     3661 taaaagaatt tgtgcgaagt caacccactt agtgtagtta ttttcggata attgttctga
     3721 aatcatcgct aactctcgtt gtggcaactg ataagagact cccttatttt ctaaggttaa
     3781 atcttcttcc attagggcgg ttaaactaac atcaaagata gcagcaatat cacttaatag
     3841 accagacttt ggagtatatt ttcctttttc ccactcactg attgaagaag agctttttcg
     3901 tcctaggaga ttagcaagtt ctaattgttc catgttcttt tttaatctaa ggtactttaa
     3961 attacttgca aaaaaagttt tcttggcgga catatttttc tccttttctt tatataaaat
     4021 atgataccat aaaagaggtt aaagcaaaag gtatcgtaaa agatggtcta aaaactctct
     4081 aaaaacttga cttcataaaa accgaagttt ataataaact taacatgatt aactaatctc
     4141 attttagtgt ggagggaaaa ttgtgaccaa atcaacttta aaagagttaa gaacaacaaa
     4201 gaaaatgaca cagcaggaat tgtctcactt aacaggtatt tctgtcagaa cgattgctag
     4261 gtatgaaaaa gatactaaaa agctaaggcg agcaaaatat gagaagctaa aaggtattgc
     4321 acaagcatta gcggtttccg ttgatgatat ttttttagga atagattcgg aatttatgaa
     4381 ctaagacgat cgttttctgt ttgctattag taagaccaat taacaaaaaa gtgcttagtt
     4441 atattgctaa gcacttttct ttgttaattt gatgctattg gcacaatcaa ttgagactga
     4501 ctgagatcga tagttaaagc atagttgctg ttgtcacgga cagtatgttc aaaatcggtt
     4561 gtgtataaga tgactcgaag ggtatctcct ttttctagat gatagatggt tggttgcaaa
     4621 ggaagtctaa cagtcatcca tttattatta ggaatagttt caattgacga caaattattg
     4681 cgattttgta aattcatgaa acctttcgaa ataacacggt aagaattttc tctaaatggt
     4741 agctctttaa ggggttctct agagaaattt tgcccattgt caatacttga ttgggtgaga
     4801 gcaataggaa gatcgcccaa gcgttttttc ttaccatagt caaggatttg tgcagataga
     4861 agtcctttat tttcacttga tttcactttt aactgtagga caatttcacc gttaataagt
     4921 aagtcctctt ccagtaaaat atcaaccagg gcttgattgg ccttgccttt aaagagagct
     4981 gctttgaacg cacggaaatc tttaccgtaa gctttaaatt catcttcacc atagtgatta
     5041 tcaattaaaa gcagttcctg accgaggtca agctctttga tggttgaggt tccaaagact
     5101 ttacgctcct gccagttttg tgggcaggtg ttatcctgcc agatcatttc aggaaggcta
     5161 aaatcattag ctaggcctaa gagtttttga cataaaaggg cattcatact ttcgcgaaaa
     5221 tcaatggatt gccaattatg catgtaaaca tgctcacctt gatgtaaaaa gaggtgcttg
     5281 ttgattgtgg aaggaagcgc attgacaatc tcatagacct gtcttggttt gacattccag
     5341 tcttgtaagc catgagtata aacgacatca cactttattt gatgagcatt ttttaagtaa
     5401 ttgcggtcgt gccaaaattg attataatca ccagattgtc ggtctaacgc ctgagactgt
     5461 tggtttagca attcttgata acgatcatta tggcgaagat aatcgccagc caataaatta
     5521 cgcgagtagg tgagctcagt taggacatct agatcctctc caggatagcc accaggacta
     5581 caaactaagc cattttcgcg gtagtagttg taccaagaag aaatagctga ttctgcaata
     5641 atcatggcta atccgtctac gcctgtagtg gctaaaccag tagacatagt tcccaagtag
     5701 gactttccag tcgtacaaac tagaccattt gcccaatcag ctctcacttg gtgggttttt
     5761 gagtggctgg tgtaggctgt ggctcttcca tttagccaat caataacggc tttaaagctt
     5821 tcaatttgag catagtctcc actcgtcata aagccagtgg aaccagcagt tcccacacct
     5881 gaaacataga tattagcaaa cccacgtgcg aggaaataat cgttgaggct ataggagtta
     5941 atgtagctaa agctttctag attttgacct ataggaagtt tgcaaggctg tgtctcaaga
     6001 ggaataaaat ccctgtcttc gacagtgatt ttattccttt ttttaacgac taactctttt
     6061 tccatacgat aaagtttttt gtcgttggct acttcattga taccttgatg gtatggacta
     6121 ggtgtcatca aagttggtaa tggtttttga gattgaggac gaatgatatt aaccttaata
     6181 agatcaagtt ggccatcttg atcggtatca agaggtgctt caacgtaaac aacttctcga
     6241 atcagctgtg acgtgtcaaa ggtagctaat gatttaccgt tgaagaagtg gtaatcattg
     6301 tccatagtaa gcattccttg gctgaccaaa tcatcaatca gggtcatgcc agacttacaa
     6361 cgggtcgcta ataagtggtg gatatgcttg ataatttctg tttcgtcaaa gtggatagga
     6421 aaggccagtt tatcaaggaa agcatcggcc tctgtaaaat caactccagg aataaagcca
     6481 aggacttgca gggccagtaa atcaaaaacc tctttggata actcttgctc tgattgaaaa
     6541 aagctcaatg cgtccatgtc atttttggcg attagatgac ttaaaggata atcactgtca
     6601 gggtagtgga agaagagttt acgtaaaaag ctttctaggt tagctttggc agttttttgc
     6661 agatccagat caaagcccaa ttcttttaat tcttcagccg ctctttctag actagttgga
     6721 atataggaaa attgattata gcgcatagga gtttcctttc tagtggctta gaaaacgata
     6781 ttatctttta atttgtcaag attggtaatg ataatatgtt gtttatcaat gcgaatgatg
     6841 tttttttctt tcaactgttt tagaatacgg ctgacgctgc tagcggtaga aatgccacag
     6901 aatttaccga gttcctcatt agtaatgaca aaattaatta aaatttggcc atttggtagt
     6961 tcttcgccaa atagggtcat taagtcatat atttgagtag aaatggcacc gatacggccg
     7021 ttagttaaca tacattgcat ttttttcatg gatttttgaa ggcgattatg gtaaaagtcc
     7081 ttcacatatc cttgtagttc aatatcttcg tttatatctt ttaaaaatgc tgagcggcga
     7141 accttgtaaa aactagcttt ctctgactcg atgcgaacat tataaggctc tcccatatct
     7201 tttgaataac cagtgttgag aacagaagta atttcaagtc ctgtaacata tctcaaatta
     7261 aattccattc catattttga aagaacactc tgcttcacaa tgccgtcttt taaaatataa
     7321 gtgaagtcct cttcgagact ttcaaaagtc aagtacttgt gataactttt ttcaatgata
     7381 ggaaagttat gattatcaat ataccgttgc aaaatgtgat gattcacgct tttctccaaa
     7441 tattctttta ccaatgtata atttgtatct tcaagagaaa ttaacatttg ctaatgccct
     7501 ttgatagtaa cacttatatt ataccattga aatatattat attctgcttt ttttgtaaaa
     7561 tgtttatgaa aatagagagg agttcatttt caatggaaga aaaattgttt aacaaacatt
     7621 ttgtggccat cacagtaata aactttatag tctatatggt ctactatctt tttacggtta
     7681 ttattgcctt tgtggcgact agagagctag gagctcagac tagccaggca ggattggcaa
     7741 cagggattta tattctaggg actttattag cccgtttgat ttttggaaag cagttggagg
     7801 tgtttggtcg tcgtttggtt ttaagaggag gtgctatttt ttacctctta acgaccttag
     7861 cctactttta tatgccaacg attagcatga tgtacttggt tcgtttcttg aacggatttg
     7921 gttatggtgt agtatcaact gcgacaaata ccattgtaac agcctatatt ccagcttgta
     7981 aaagaggaga aggaattaat ttttatggct tgtcaactag tctagcagca gctattggcc
     8041 cttttgtagg aacctttatg ttggataatc ttcatattga ttttcgcatg attattgtct
     8101 tatgtagcgt cttgattggg tgtgtggttg ttggtgcttt tgcttttcca gtcaaaaaca
     8161 tgtctttaaa tgcggagcaa ttggctaaaa ccaaatcgtg gactgtggat agtttcattg
     8221 agaaaaaagc cttgtttatc actgcaatcg cctttttaat ggggattgcc tatgcttcag
     8281 ttttaggatt tcaaaaatta tacacgtctg aaattcattt gacagcagta ggtgcttatt
     8341 tctttgtggt ctacgcctta atcattacca tcactcgtcc agcaatggga cgtttaatgg
     8401 atgctaaagg cgataaatgg gtcttgtacc caagttatct ttttttagca atgggactct
     8461 tcttgctagg tagtgtatcg tctggaggaa gctatttgct ttcaggagcc ttgattggct
     8521 ttggttatgg cacttttatg tcttgtggtc aagccgcctc catacaagga gtggatgagc
     8581 atcgctttaa tacggctatg tctacttata tgattggtct tgatttaggt ttaggtgctg
     8641 ggccttacct cttgggcttg attaaagatt tggcacttgg tagtggtgtg gcttccttta
     8701 ggcacttatt ctggttagct gctgtgattc cactgatttg taccttgctt tacttgttaa
     8761 aaacaaagac aagacaggtt gtgtcttaag gacaagaaaa ggagtttagt cttatactta
     8821 aatacaaacg tatcttaaca gctgtagata gttcctatga gccgggatta gctgtgggta
     8881 aagccgttac tgtagcgctt tgaaataatc ctagtttgct attggtacat gtcaataaaa
     8941 atgactcgca aaagccattc gtgaaagaga aaatgtggcc ttatttttag taggtgcaat
     9001 tggattaaca tcagaatata ggatttgtca tgttaagatt gatctgttga tagtgagagc
     9061 taataaaaaa tgttataata ctatgaaata aagtgataaa gataaggtct tttatggtcc
     9121 ttttctttac cgcttttatt attgtgtgaa aataacactt aatgatcatt ttatttatta
     9181 ttttattacc tttacattca tcaataagcc tgttaaaatg gtatttgtta tattttatta
     9241 tttggaggaa accagaaaac atggaaatga catggactgt gaaatacatc acagaattta
     9301 tcgcaacggc ttttttgatt attttgggga atggagctgt tgctaacgtc gacttaaaag
     9361 gaacaaaagg acataactca ggttggttag tgattgcttt tggctatggc ttaggagtta
     9421 tgatgccagc tttgatgttt ggtaatgtat ctggaaacca tattaatcct gctttcacag
     9481 ttggactagc agtgtcaggc ttgttcccat gggctcacgt cttacaatac gttgtggcac
     9541 aattacttgg agctatcttt ggtcagttgg tagtggtaat ggtttataaa ccttacttta
     9601 tgaaaactga aaatccaaat catgttttag gctcattctc aacgatttca tctcttgata
     9661 atggtcaaaa agacagccat aaagtctctt atatcaatgg tttcttaaac gaatttgtag
     9721 gttcatttgt tcttttcttt ggtgctttgg ctttgactaa aaactacttt ggggtagagt
     9781 tagttggtaa attgattgaa gcaggttacg accaaacaac tgcagcaaca caaatttcac
     9841 catacgtgac aggctcattg gcggttgctc acattggtat tggtttctta gttatggtct
     9901 tggttacttc attaggtgga ccaactgggc cagcactaaa cccagcgcgt gattttgggc
     9961 ctcgtttgtt acaccacttc ttaccaaaat cagttcttgg tcaagccaaa ggtgattcaa
    10021 aatggtggta tgcatgggtt cctgtagttg cacctatctt agcggcgata gtagccgtag
    10081 cagcgtttaa atacctttat atcagataaa aaaagaacta aagcttcttt tagactcaag
    10141 acaagctcgc ttaaggaact tgtcttttta tatgagttaa gcgaaatcta atgcaaactt
    10201 gactgtcttg tatagcgtat tttgtaaatt ttactagact tcttgtaaaa aagcctctcc
    10261 tcagataaga tgactaatgc ctctaaacgg tgttacaaat aaacgaggca tccctaactt
    10321 cctttatctg gtgttgaaac tattttgcac ggactaaatc actgatagag taaaaaacga
    10381 tttttcattt ttgttgtaaa atattaaaaa cgtctctggt tagtgattcc cagaaacgtt
    10441 atcttatcta tttgtttgtt gcttatgaga ggtaaaggag gaacgaatca gcattccacc
    10501 agtgaagaaa acgatagcga tgaccagaag tttcaagcta ttaatatcta aattcgttaa
    10561 gaaaaacaca gctagtaaaa cgccaataat accaccagaa acaattccag caaaaccatc
    10621 ccaactgaca cggtttgctt tgataaactg gctactagaa gctgtcataa tcatagctgc
    10681 atctagcatc ataacaggca tagcaactgt tgggctaaga cccattaatg aaaagaaaat
    10741 caattctgga gcataattgc ctaaccccat agtcatcaag actccaacga taaaattaaa
    10801 accaattcca acaaaaagcc agatgccatg gaggccatga atggtgtctg aaaggtgttc
    10861 tcctggatgg tagattattc taatgatcat gattatagct gctatgatta aaagactacc
    10921 aaggattcgt tggacagttg gagcatgcca gttttttgta atatgagtcc ccaaataagc
    10981 tccaataaaa gctgctgcag ccatagcaag taaagttaga acctcaactt ttacgacaaa
    11041 aataaagcaa agagattgaa tgagcaccgg aagcacatga gctacggtca tagtgccagg
    11101 caattgtcta tcgtcagtga ctaatttagt taacttaaag cacgttgtgg tagtagcaaa
    11161 agaccctatc ccaagggtgt caagggcatc tgttagcagg ccaatccaaa accccgtcca
    11221 aaagcgttta aaaggattga tcttattttt tttaagatgt tttactaaca taaagaaaat
    11281 aaaaagcatt gccgaaacta gcaaagcttg tatcagtcta aggataagca tttcgttcat
    11341 aaagactagt ttacaaaaaa aaaccttagc cgtcaacgtg atttacttca ttaaaacatg
    11401 ccactatgct tagaagagct ttggttcgat gtattttgtt aaaattaagc taaaatatta
    11461 atattgcatg aaaggggacg ccttcctttt tcccttactg agcttagctg ttattgtagt
    11521 gaatgtttaa aaggctagtt tgtcgctctt tatcaaaaat ctagtaggat gaatacgtat
    11581 aatttcttgt caaatagagg aattttgtct ataatagcag aggattagga ggaaattatg
    11641 actttaatgg aaaatattac ctttaaaact ccagtattac gcgttaatga tcgcgacctt
    11701 aatattgcat tttatcaaaa taatttaggg cttcgtttag tatctgaaga aaatgcgatt
    11761 gctatctttt catcttgggg agaagggcag gaatgttttg taattgaaga gtcaccttca
    11821 gttagaacgc gtgcggtaga aggccctaaa aaggttaata cgattgtcat caaaacaaat
    11881 caacctaaag aaatcgaaca attattagct catggagcac attatgatac tctttttaaa
    11941 ggtcaaaatg gctatgcctt tgagactatt tccccagaag gagaccgatt cttgttgcat
    12001 gctgaacaag atattaaaca tctccaaggt actgatttac catcgcttga aaaagatgcg
    12061 acttttaaag gtttaactca atttaagttt gatattattg ttttaaatgt tattagtgaa
    12121 gaacgctcaa aagcttttta tcgggatctg tttagtgatc agttacctat tactatggat
    12181 tttattcaag aagaaggtcc cgatttggca attgatcccc atattgcttg ggatttagaa
    12241 attttagaat ttcaagtctc aaaggactat gatatgaagg tcctaaaagc aactttagaa
    12301 gaagacgggc acaaggtcta cattgataaa aaacacaaag tattggtcct ttctgatcca
    12361 agtcagatcg aagtatggtt tacgaaatga ctttggcagt cattaaatgt attgaaaacc
    12421 atcttcacaa aaaagtatac aaaggggcca gtctggctct ctttcaatct ggtcgatggc
    12481 aagaatacca tatcggaaca attgatggaa gacgaccagt tgatgctaac ttagtttatg
    12541 acttggctag tgtttcaaaa gttgttggtg tggccacaat atgcaatatt tattgaataa
    12601 tggtacgtta gcattagatg atcccttaaa agtatattat cctagtattg ctgatacgac
    12661 tgtcactatt cgacagttat tgactcatac cagtggtctt gatccttata ttcctaacag
    12721 agatgtttta aatgcacaac aattaagaaa agtacttaat catcttactc aaaaagaaaa
    12781 taaaaacttt tattacacag atgttaattt cctcttgtta ggctttatgt tagaagagct
    12841 ctttagtgaa tctttagacc agatatttga taagactatc tttactccct ttgggatgta
    12901 tcatacgtct tttggccctc gtccagaagc tgtaccaaca ttaaagggtg tgagtgatgg
    12961 agaagttcat gatcccaaag caaaaatctt aaaaaaacat tctggatctg cggggctatt
    13021 ttcaactctt gcagatttag aaagttttag caatcattat cttaatgatc cattttcaga
    13081 ttgtctgtgg cgcaactaca gccaacaaac aattgagcgg tcactagggt ggaatttaga
    13141 tggcgattgg attagtcata caggttacac agggccgttt ctaatgctta ataaaaaaga
    13201 gcaaacggca gctatttttt tgaccaaccg tacttacgac gaggatgata aaagtaaatg
    13261 gttaaaagaa cgtcagttgc tttacaatgc actaaagcat gatctgacaa cacccgtatc
    13321 gtaacgtcta aaggggcagt tttagtgatc ttattactgt ttttaaagtt tcttctaaaa
    13381 aatagccatt tcatttgtct gatgcgatta gagtgattat aagtgaaaaa agaacagcca
    13441 tctcattttg aatcaaatga gatggctgtt cttttttata agttattgat catttagata
    13501 ctactattta cttgaaatag cttcagcggc atcatccatt gaaagcactt cgtggaagac
    13561 acgttgagtc aattcagttt tttgttctgg tgtaaggtat ttggtgttga cacagtaacc
    13621 agagatacgc acgataacgt cttcgccgtt catgattttg tcataaacat cgttaaggtc
    13681 cataacgttc aagttaacgt gctgaccacc attttcaaag taaccgtcaa gcactgttac
    13741 caagttgtca acttgttcgt caaatgtttt accaagagca cgaggtgata cttgagtagt
    13801 caatgagata ccatcgttag catgtgagaa ttccagttta gcaagtgagt taaggttttg
    13861 taaccagcca ccttttgctt tgttagatgg gttagcacct ggtgagaaga attccacttg
    13921 gctagtgtta actgtaccat cttcgttcaa gaagacgccg cggtgaactg gagagttacc
    13981 agtttgttta gagtaagcaa cgtttgaagt gatggtaaga agtgatactg aagcctcagc
    14041 attcttgtaa agtttgtggc ttgcaagacg tgtgtggtaa gcttccatca accatttcgc
    14101 gatgtcatca acacggtcgt catcttcacc gtaacgaggg aagtcacctg ttacttcgta
    14161 gtcataaatg tagccatttt catcgcggat agttttaaca gttgcgtatt taatagctga
    14221 caaggtatca actgtgttag cgaaaccaca gataccgaat cccatgttag cacgttggtg
    14281 tgttggcaag aaggccattt gaactgcttc gtagttgtat ttatcagtca tgtagtggat
    14341 gatgttaagc gcatctacat aagtatctgt caaccagtca agagatttct caaagttagc
    14401 cataacttcg tcgtactcaa ggacttctga tgtgattggt tcaacaacgt taaacacttt
    14461 gtagtctctg tgaacatcat cgtaaccacc gttaagacca gtaagaaggg ctttgagaac
    14521 gtttacacga gcaccgaagt attggatgtt atgacgttgt tcttcatttt ctgggtcaag
    14581 tggtgataca caacatgaaa tacatgacat ttcaccataa ccttctttag ccattgttgt
    14641 cacaccttca tattggatag aagagtgttt gtggctcatt ttcatacagt agcgacggaa
    14701 tgtttctggc agttggtcag tccaaagaac tgttaagttt ggttctggag agttaccgat
    14761 attatcaaga gtgtttaaga aacgatagtc catcttagtc acacggtgac gaccgtcgtt
    14821 acccatacca gccatagaag ttgtgatgaa tgttgggtca cctgagtaaa gggcatcgta
    14881 agctttagta cgaccaaatt ttacggtacg gagtttaagg acaaaatcat caacaaattc
    14941 ttggatttct gattctgtaa aggtaccgcg agcaaggtca cgttctgcaa agatatcaag
    15001 aacgattggc acacgtccaa gagaagtagc agcaccgttg atcacacgac atacagccat
    15061 gaaagcgatg tttacccatt ggatagcttc tttaacgttt tgtgctgggc gacgaacatc
    15121 aactccgtaa aggtcaccaa gtttaaccac ttcaccaaga gcttggtatt gaaggttaac
    15181 ttcttcgcga agacgaatgg attcttcatc gatttcagtg atagcattcc agtcattgac
    15241 tttttcttgc atcaagtagt cagcaccgta aagagcaaga cgagcgtaaa caccgatgat
    15301 acgtccacgt gagtaagcat ctggaagacc agttacagtg tgggcatgac gagcacgacg
    15361 aatatttgaa gtataagcgc ggaagatacc gtcgttaaca gttgtcacgt acttagtaaa
    15421 gatttcgtgt actgctgggt ctggttcata gccgttttct ttaagggtcg tttccgccat
    15481 acggatacca ccttttggca tgaagttcaa tttgaacaat tcatcgtttt gaataccata
    15541 aattaattca ttttctttat cgatgaaacc agcaggaatg tcagcaattg aagttggacg
    15601 agtatcgtat gggaaacgtg tagcttcata gtgtgctttt gtttcttcga taactttttt
    15661 gatgtgaagt gaacgttcag tagcaccagc caagaaagat tcatcgccat cgtatggggt
    15721 gtagttagct tgtacaaaac gtgagacact tgctttttct ttccagtcag ttcctttaaa
    15781 gctttcccaa gctttttcga aaacatctgt attggtttta acagttgcca taaatttctc
    15841 cttaaattct agtaacaaag cgatctgtta catttacaat tctaagttta acacatagga
    15901 aacgttttcc caagcaaaat tcttgacaaa attaagattc ttttataata cagattgttg
    15961 aaacagtcac aaactgtatt agaatgtatt ttttttggct ttaggtagcc taaaaggtat
    16021 aatagggaaa ggagggactt atgcttattt ttccactgat taatgacacg tcacgaaaaa
    16081 tcatccatat tgatatggat gccttttttg ctgcagttga ggaaagggat aaccctgctt
    16141 taaaaggaaa gcctgttgtg gttgggaaag atccaagaga aacaggtggt cgcggagttg
    16201 tttccacttg taattacgaa gcgagaaaat atggcattca ttcggccatg agctctaagg
    16261 aagcttatga gcgttgtccc aaagccattt ttatttcagg aaattatgaa aagtatcgaa
    16321 cagttgggga ccagatccgc cgtattttta agcgttatac tgatttggtt gaacctatgt
    16381 ctattgacga ggcttacctt gatgtgactg ataataagtt ggggattaag tcagccgtca
    16441 aaatagccaa gctgattcag catgatatct ggaaagaagt aggattgacc tgttcagcag
    16501 gtgtgtctta taacaaattt ttggctaaat tggctagtga ttttgaaaaa ccccatggcc
    16561 tcaccctagt cttgaaagaa gatgccctgt gctttttagc caaactcccc attgaaaagt
    16621 ttcatggtgt tggtaaaaaa tcagttgaaa aactgcatga catggggatt tatacaggac
    16681 aggatttgtt ggcagttcct gaaatgacct tgattgatca ttttggtcgg tttggttttg
    16741 acctttaccg taaagcgaga ggcatcagca attctcctgt caagtctgat cggatacgca
    16801 agtcaattgg cagtgagaga acctacgcta aactgcttta tcaagaaaca gacatcaagg
    16861 cagagatcag taaaaatgct aagcgcgtgg ccgctctctt acaggaccat aaaaagttag
    16921 gcaagaccat tgtgctcaaa gtgcgttatg ctgattttac caccttgaca aaacgtgtca
    16981 ccttgccaga attaaccaga aatgccgcac aaattgagca agtagctggg gatatttttg
    17041 acagcttaag cgaaaatcct gctggtatcc gcctgttagg ggtaaccatg accaatttgg
    17101 aggataaggt agctgatatt tccttggacc tataggagaa agagggctct atccgtccgc
    17161 ctcattttgg agaaaaaaga agctgattag ggatttccct aatcagcttc tttggtccat
    17221 tattttatta cagcatagct tggtctgtat catcaccttt ttcgttaagg gttttagcct
    17281 tgtaaaaagc aaagccataa agagcagctt gtataaggat aaggatagtt ccaaccattg
    17341 acaaggttgt tgtgaactgg ttaaccaagc cgataacaga aaggataagt cctaagatgt
    17401 aaggaatata actaaccgtt aatccttgtt ttagtttgga taagttttga gcacaaaaga
    17461 caatgatagc aataatagca aggacattta agacagataa gaaaatcata aatggtgtca
    17521 tgctgctttg tagctgtgcc aattgctcag ttgttaattg ggcccgaaat gcttcattct
    17581 tgagttggct ttgtaagtag aaaatccctg caaatcccat taatgacagt acaactccaa
    17641 gcccgtttag aataataatg gcaatagtag acgttttgag tgcctgacgc actttttcat
    17701 aagaaatcat ataatcctcc tagagtcctt aatccgaaat tgtataatgt gtttaataca
    17761 aaaatattat accatagatt aatcaaaaat gtccgttttt ctaggatttt ttctggaaaa
    17821 agagggcaat atctgactct gtaagcccta tcatcgaatc gatagtcgaa taattctcag
    17881 gtgttaacct aaaatcatca ttatctgact gagagttctc agtggggtta gcgtttgttg
    17941 attgagagga agatttttga gagtcgtcct caagggttgc cgtattagaa aaaagggagg
    18001 tttgctcttt tgattttagc tcttggttag gttgagagga ggctaagtcg gattgttctt
    18061 ggaagcgttc gatcaagtag gtttggcgtt tatcgccttc gtgtttaata gcatactcaa
    18121 aggcagtata ttctcccaac agaattaact tacttttaga ccgagtaatg gccgtgtaaa
    18181 tcacatttcg ttgcaagagt cggccgcttt ggcgtgtgat aggtaaaatc accacttgaa
    18241 actcactccc ttgcgattta tgaatgctca tggcataggc cagggttaat tttagccatt
    18301 catttctagg gtacgtgact tcgctaccgt caaaatctaa gattaattcg tcttgtttag
    18361 attcggtgta tttagcagga atcaaatctg taatataacc aatatctccg ttaaagacat
    18421 tcaactgagc atcgttgact aagtgcagga ctttatcacc tttacgaaaa tgcgtatcat
    18481 tgaacagaaa ttctgtttgt ccttgcaagg gattgagaag ttcttgcatg agttgattaa
    18541 gatgattgat gccagcttgt cctttgtaca taggcgctaa aatttgaatt tcctcagcag
    18601 ggatgccact tttaatagca gataggacaa ttttttgaat catgtcaggg ataaaggctg
    18661 cttgggcttc aaaataagaa cggtcagctt ttttatcacg aaagtcagca gctaagattc
    18721 ctcgacgcat ctgatctgcc aaattgacaa tagtagattc ttgggattga cgaaatatct
    18781 tttgcaaggc gatttggggc aggctattga cttttaaaag atctgacagg acttgaccgg
    18841 gtccaaccga aggaagctgg tcactatctc cgacaataat cacttgagtt gttgagttaa
    18901 tagctcctaa caactggttg gcaagccagg tatccaccat tgaaaattca tcgacaatca
    18961 gcaagtcgca gtctagataa tcctccatgg cttggtaatc gttgtcgcca ttgaggccta
    19021 agtgcctgtg gatggttgcg ctaggaagtc cagtcaactc attcatgcga cgtgcagctc
    19081 gacctgttgg agctgctaac aagataggaa ggtctttttt atccaaatca atctgatgca
    19141 ggttcgcgta agcctgcaaa atgcctcgaa taacagttgt ttttcctgtt ccgggaccac
    19201 ctgttaggag aaagaccttg ctggttaagg ccttagtaat ggcttcttgc tgcacttggt
    19261 cataggtgat ggcaaagtct ttttgaacgg cttggatggt tgtttgaatg gtatcatgac
    19321 taaatgactg acttaaaggg gtatctaaga gacgagagat gttgttagca atcccttctt
    19381 cagcaaaata aaggctagca tcaaacagtt tggtgtcact gtttttgatt ttgccctcta
    19441 tgattaactc gcttagttgc tcagccacag cagcaggatc acattctact tgacgtgcat
    19501 cttcaaggag tgtgatggca aagtctaata attgtcgtgc ttgaacataa gtatctcctc
    19561 gattgatgga ttcttccaag agacaatgaa ggagggctgc acgaaaacgt ttcggagagt
    19621 cgctttcaat ccctaagttt tcagcgagag catctgtcat tttaaaccca aaaccttgta
    19681 gatcttcgac taactgatag ggattttctt taacaaggtc aagagcctct tctttatact
    19741 tttcaaacgc ttgaaaggca aaacggttgc taagtccaag ttcgacgaga ccagcaatca
    19801 gttgctctgt gccgtaattc aattttagtt tagcgacaaa ggcttgacga ttagccttgg
    19861 acagaccaga gatagtttct aatttacttg ggtcttctaa aatatggtca atggtattat
    19921 gaccatatag cgcaatgatt ttctccgctg tttttttacc aatcccctta aaatggtcac
    19981 tagagaaata attaaccaaa ccagatgaac taggtttgat tttttggtaa cggcttagct
    20041 tgagttgttg accgtattta gggtgctggg tcaattctcc ccaaaaggtg tagtcatctc
    20101 cttcaataat gtcagccatc gttcctgtga taatgatttc aaagtcgtca atgtcactgt
    20161 ctgtatcctc aatggcaagg aggagaattt taaagaaatt agcctggttt tcaaaaatga
    20221 tacgatcaac agtacctgta aaaacgtatt ccatagtaac tctttctatt tatacaagat
    20281 aactgaaaac ctgcccaaag gcaggttttt tctaattaaa gacggtcatt ttattgagtg
    20341 gccaaaaacg agctttcact tcaccgataa ggttttcttt tttgaaacta ccaacttcgc
    20401 gactatcccg ggaaacaata cgatcatcac caagaagaag gtattctcct tttggaacac
    20461 tcatctcaaa gcgtgtttgt ccctcagaat tagttgtaaa agcatcagat gtttctgcta
    20521 actgttggaa tagggtatta taggcgtaag ttttttggag tttatcgttt ttaaattgtt
    20581 ttagatactc agccaaatac ggctcaactg tttttttacc attaatataa agtgtgtcat
    20641 cattataaga aatggtatcg cctggcaatc caataactct ttttacgatt tctttctttt
    20701 gtccgttttc ttcttcctga gcaactacaa tatcaaagcg atcaatccta gcttgattaa
    20761 aaacgataag gcgttcgcca tgagctagag ttgggtccat agaatggccg tctactttaa
    20821 cagcctgcca caaaaaaaga cgagatagac caaagagaat taaaaagaga gtgaatgggc
    20881 cccattcttt aataaactgt ttcatatgat tccttttatt tagtgagaag cgcttgcgct
    20941 ttgtgagtgt tggcgaagtg aagtttagca ctatattcta agctagacat accataagcg
    21001 gctaagagtt ggctagcaac tttatctgaa gctgaaccag caccgcttgg gagttggtaa
    21061 cctaaatctt gacctaattg atcgagattg tctaaaaata gatttctagc aatgatagag
    21121 ctaacagcca cagccaaata gtgactttct gccttttctt gaaaggttag aggatttggg
    21181 aaatggtttt tttccttttt tagatgcttt tcataatttg attggctagt gaaagcatca
    21241 ataacaattt gtttaggttg aatgcctttt tgtaacaaca aaaaaatagc ttggttatga
    21301 agagcaactt tgatagaaat ggcattatat ggtttacttt taccaaccaa ttcgttatat
    21361 tttttaggtg ataggagaag tgattgatga ggtatttgtt tctctaacag aggcgcaatc
    21421 tgttgaatgg ttttatccga taatttttta gaatcatcaa ccccaagctt tttcaggaag
    21481 ggatgatctt taggatcgac aaaacttgcc acaacagcaa tcccaccaaa ataagagcca
    21541 ttacccacct catcactgcc gattataggt atatcttggc tattgttgct tgcttcaaaa
    21601 actgtcttag ctactggaag attaagctct tgagctaaag catttgcacc gtttccctgg
    21661 agaactaatt ttccggattt gtacagcaaa acagtaaccc catttttttt agcagcaaag
    21721 gctacatagg tattttggct actgatggtg tagggggcta gctgtttttt taaatgttta
    21781 ctcagtatag catctatttt caaaactaag gtattcataa taattatttt aacataaaat
    21841 agttgactat ggttaattca taagtttatt taacaaagaa aacagagact cgaatgttta
    21901 gacgggttag ggcaatggtg ttgactattt tacgaaagtt tcattttacg gtataatgct
    21961 aatgaggtga ccctatgaaa agtattaatc gctacaaatt cacctttggt gaaaaaacat
    22021 taacattgac aactgacaaa gacaatctct ttatggaaga agttgagcgg gtagctaaag
    22081 aaaagtatca ggctcttaaa aatcatttac cagaagctga tgacgagact atcgctattt
    22141 taatggctat caataccttg tcaacacaat taagcagaga aattgccatt gaaaaaatgg
    22201 aagctgaaat tttagattta cgtcaaaaaa ccttggttgg tcttcaagaa aaagctaatc
    22261 aaatagatgt gaatgaggtt taatcatgtt atctttattg atagtgcttg ttttaacttg
    22321 gaatttttat attggttata gtagaggtat tattcttcaa tcgttttatg tcttaggagc
    22381 cctactttct cttttggtag ctaatcgatt ttatattgga ttagcccata agctaacgct
    22441 ttggattcct tattctaacc cggtagaagg aacatcagtc tttttcttta aatcagttga
    22501 tatctttgtt ttagataagg tttattatgc aggccttgcc ttttttatca ttttcttatt
    22561 ggggtatgca ttgagtcgct ttcttgggat ttttgttcat ttccttttgc tagattattt
    22621 tgataaccag tggacaaaat gtttgagtgg cggactagcg cttctagtat cgcttctttt
    22681 tttgaacatg ttactgtcta tttttgcaac ggtccctatg ccttttttac agcactattt
    22741 gcactctagt tttcttgctc gtttggtgat cgaacacctt ccaccattga caataattat
    22801 tcaaaaattg tggattcaag ccattatttg atatcgtttt gtgactaata taagaacctg
    22861 gagtgagttt cacctttagg ttctttattt acgagaaact gtttagaaat aaagagaacg
    22921 catgggaact tagtgacttt cttgccacat tttccatcat tttaggtata atgaagagta
    22981 tgaataacaa gattttagag cagttagaat ttaacaaagt taaggaattg ctattacctt
    23041 atctcaagac agaacaatcc caagaagaat tattagagct ggagccgatg acggaggctc
    23101 ctaaaataga aaaaagtttt aatgaaattt ctgacatgga acagattttt gttgaacatc
    23161 actcatttgg catagtcagc ctaagttcaa tctctgagag tttaaaacgc ttagaacttt
    23221 cagctgatct taatattcaa gaacttttgg ctatcaaaaa agttttacag agttcttcgg
    23281 atatgattca cttttattct gatttggata atgtttcttt ccaatctttg gatcgtttgt
    23341 ttgaaaattt ggaacaattc cctaatctgc aagggtcttt tcaagctatc aatgatggtg
    23401 gttttttaga acattttgcg agtccagaat tagagcgtat ccgtcgtcaa ttaacaaata
    23461 gtgaacgacg ggttcgtcag attttacagg atatgcttaa ggaaaaagca gagcttttat
    23521 cagaaaatct aatcgctagt cgtagtggac gaagtgtcct accagtaaaa aatacttatc
    23581 ggaatcgtat ttctggtgtg gttcatgaca tctcttcttc gggaagtact gtttatattg
    23641 agcctcgtgc tgtagttaca ctaaacgaag agataacgca gcttagagct gacgaacgtc
    23701 atgaagaagg tcgtatttta cacgcatttt cagacttgtt aagacctcat gtcgccacta
    23761 ttagaaataa tgcatggatt cttgggcatc ttgattttgt aagggctaaa tatcttttta
    23821 tgtctgataa taaggcgacg atacctaaga tctctgatga cagcacgtta gcattaatca
    23881 atgttcgtca tcctctttta agtaatcctg tggctaatga cttacatttt gatcacgatt
    23941 taactgcaat tgtcattact ggtcccaata ctggtggtaa gacgattatg ctaaaaacac
    24001 tcggtttagc acaattaatg ggacagtctg gtttgccagt attagcggat aaaggtagta
    24061 aaattgcagt atttaacaat atctttgcag atattggcga tgagcaatct attgaacaaa
    24121 gtctatcaac tttttctagt catatgacgc acatagtcag tattttaaac gaggctgacc
    24181 acaatagttt agttctcttt gatgaactag gagcaggaac ggatcctcaa gaaggtgcta
    24241 gtttggccat ggctatttta gaacacctta ggttaagtca tatcaaaacg atggcgacca
    24301 cgcactatcc agaattaaaa gcttatggga ttgagacaaa ttttgtagag aatgcgagca
    24361 tggaatttga tgcagaaacg cttagcccca catatcgctt tatgcaagga gttcctggac
    24421 gctcaaatgc atttgaaatt gcttctcgcc ttggtttagc tccatttatt gttaaacaag
    24481 ctaagcagat gacagattct gactcagatg ttaaccgtat tattgaacag ttagaggcac
    24541 agacacttga gacacgtaga agactggatc atattaaaga agttgaacaa gaaaacctca
    24601 aattcaatcg tgcggttaag aaactctata atgaattttc acatgaacgc gataaagagt
    24661 tagaaaaaat ctatcaagaa gctcaagaaa ttgtagatat ggctttgaat gagagtgata
    24721 ctatcttaaa aaaactcaat gataagagtc aattaaaacc tcacgaaatt atagatgcta
    24781 aggcacaaat aaaaaaatta gcacctcaag ttgatttatc aaaaaataaa gtcttaaata
    24841 aggctaaaaa aatcaaagca gctcgtgccc ctagaattgg tgatgatatt atagtgacta
    24901 gttatggaca gcgaggtacc ttaactagtc aattaaaaga tggacgttgg gaagcacaag
    24961 tgggaattat caaaatgaca ttaacacaag atgaatttac ccttgttaga gtccaagaag
    25021 aacagaaagt caaaagtaaa cagattaatg tggttaaaaa ggctgatagt tctggaccaa
    25081 gagctcgact tgatcttaga ggtaaaagat acgaagaagc aatgcaagag ttagatcatt
    25141 ttattgatca agcattgctt aacaatatgg gacaagttga tatcattcat ggtattggta
    25201 caggcgttat tcgtgaggga gtgacaaaat atcttcgtcg tcataagcat gttaagcatt
    25261 ttgcttatgc cccacaaaat gcagggggat ctggtgccac aattgtaacg ttagggtaaa
    25321 tgatggaatc atatgaacac ttttatgcca aactatctca accttttaga aaatccccac
    25381 agttaataat tcttttaaat gttttactaa aaataatcac aggagtgatg tacatacttt
    25441 atccatcttt tctgatattt acgctttggc aagggatgac atttcaatta tggttaaggc
    25501 tattaattat tcctgctgtt ggctttatag ctttgtctta cattaggaaa cgctttgatt
    25561 ttccacgacc gtatgaaaaa tggaatatta aacctttaat tgataaggat acaaagggaa
    25621 ggtcaatgcc tagcagacat gttttttcag ctacgatgat tagtatgtgt ttgttacgat
    25681 attatgttta ctttggaata gtttgtttaa tattatcggt tttattggca atttgccgtg
    25741 tgatagcagg tattcactat cctaaggatg ttattgtagg ttaccttatt ggcttgatgt
    25801 tagggctttg tttattgatt tagcgagttc gtagcaaata gtttcaaaaa caactaaatt
    25861 cttgtacaat aggcttatca ttaagatgaa atggagaaaa aagatggcat tagaagtaac
    25921 agatgctaca tttgtagaag aaactaaaga aggtttagta ctcattgatt tttgggcaac
    25981 ttggtgtggt ccatgtcgta tgcaaacacc aatcttagaa cagttatctc aagaaatcga
    26041 tgaagatgaa ctcaaaattt tgaaaatgga tgttgatgaa aatccggaaa ctgctcgtca
    26101 gtttggtatt atgtcaattc caacattgat gtttaaaaaa gacggagaag tggttaaaca
    26161 agttgcaggt gttcatacta aagaccaact gaaagctatt attgctgaat tgagttaact
    26221 aaaataaagc ccagcgtcac gctgagcttt attttatgac ctactaactt caatggaata
    26281 accatgtgaa cataaaacga cttgcaaaag caatagcaac agtaatgagg aaaaatacag
    26341 tgacaataag ggggttctga taaggaagtt ttgctctttc ttctcgtttt tcgatttcgt
    26401 ctaataattt tccacttgaa acagctagga tttccttata aggttgcaca tcatattttt
    26461 tcttaaaacg ttccacacga ttagcataag tcatagtaat tatcgataat aaaacaaaaa
    26521 tgccaagtcc tagccactct aagaaataga ctaatggata acttgaaatc attaatagta
    26581 tcatcaatgt taccattact ttggtatctc gtttaaaatt ctttttatca acctgagtga
    26641 tggtatattt cattttctca atgtctcttt taatgagttg gtctaagctc acttgaaaaa
    26701 tttgacttag gagtaagagg ctatggatgt ctgggtaagt tttgtcattt tcccagttag
    26761 atatgctctg acggcttaca tagactttct cggctaattc ttcttgcgag agcgcttgtt
    26821 gtttacggta gcgaataatt tgctgaccaa tttccataaa tatctccttt cataatatta
    26881 gtataaggat gataagctaa cgggtctatc aaatgtattt gacattaggg atagaccact
    26941 atttataggg tattaaaaga taatctgagg aaaactttac agcgacgtaa aggaattgta
    27001 aacaaaaagt gaaccgtcat agttcacttg tgattaagta tttttctgtt ttaagtaggt
    27061 ctctagcatt ttcttttggg gcgttgcaaa gggataaaga gaaaagtcct caattgctac
    27121 ccactttagg tgaggagcat taggtaaatc tgttgctttg accaccccct ctatgagttc
    27181 tattgtccac ttctggtgac taaaagtgtg cttaatattt ggaaagtgat tatcagtcca
    27241 ttggggcttt aattgatatt ctctttcgaa agtttcattt tgggtttgcc agattatggg
    27301 gttggattga ttgtcatcaa ataaatctaa ttgttgagaa agaggtgacg tttcgataat
    27361 aggaaatgac caaaaacctc ctagaagtct ccctttagta tttttctcca gtagatattg
    27421 gccattttgg ttacgaatga caaaagcctg aattcgcatt ggtttaggct ttttctttgg
    27481 attttttatg ggatatttac cataagtacc attcaaataa gcagcgttaa agaaacgaat
    27541 agggctttca tcaggcctag gtgtcttagc ggactcgatg tctgtaccta gatccataag
    27601 tgcctggtta aaatcaccgg gtctgtcagg gtcaattagt atttccataa tagcttgaaa
    27661 aattttacga tttttagggt caccgatatc ataattaact tcaaacaaac gagccatgac
    27721 acgcatcaca ttgccatcaa cagcaggctc tggtaagttg aatgagatgc tggcgatagc
    27781 acctgcagta taaggaccaa tcccttttaa tgaagcaata tcatcataag tgtgaggaaa
    27841 tatgccacca aaatcaacca tcacttgctg tgcagccttt tgcatattac gcacccgaga
    27901 ataatagcct agtccctccc atgcctttag taattgttct tcaggagcgt ctgccaaatc
    27961 ttttatttga ggaaaccact ctagaaaacg tttataataa gggattaccg tattaacttg
    28021 tgtttgttgc aacatgattt cagaaaccca aatataatat ggattagtag ttcttcgcca
    28081 agggagatca cgtttttctt ggtcatacca ccctaaaagt gtgcgacgaa aagaagcgat
    28141 tgtctcatta tcccacatat taataccata atcttttaat tcaatcatgt tgttattgta
    28201 acacaggagc cttaaaaaga gtaaaaaaag attttaggta tttgcgaaaa agaaaaggaa
    28261 atattataat aatattaggt ttacctcatc taaatgttga tttagaataa ctgaaattaa
    28321 cgatagaagc agacaggttt taatttggag gggacatgtt ccagaaatta aagaatctta
    28381 ttgatcggta ttcgtggttc gtttttataa tgatgattct tgtgttattt cttaactata
    28441 tttatccatt tgatccttct ttgagcggac tacagttgga atggctgatc atgacgcaag
    28501 tttttcctgg attaggtatc gtatgtgcca tggttgctat tatttttaaa aagtttaacc
    28561 tttttgtttt ggccctaatt ttatattttg cactttggtt aaaacttttc cttgcttttt
    28621 cttttttcac ctatttttta ggagtctgac taagtgccaa tttttaaaac tcgtgaaaga
    28681 aaatgtttga caaaacttag tcaagtagaa aaagttcctt gcttttaatt gactattagt
    28741 gtacaataag attctgtgag tatacctcac ttactcactc caaaagtagt gagtcattag
    28801 accaaaagga ggaaaatatc aatggctaaa tacgaaattc tttatatcat tcgtccaaac
    28861 attgaagaag aagctaaaaa cgctttggta gcacgctttg actctatctt gactgacaac
    28921 ggtgcaactg ttgttgaatc aaaagattgg gaaaaacgtc gtcttgcata cgaaatcaac
    28981 gatttccgtg aaggacttta ccacatcgtt aaccttgaag cgactgacgc agcagctctt
    29041 aacgagtttg accgtctttc aaaaatcaat ggtgacattc ttcgtcacat gatcgttaaa
    29101 cttgacgctt aattccaact aagagggtag tttatgatta ataatgtagt actagttggt
    29161 cgtatgacca aggatgcaga acttcgttac acaccaagtc aagtagctgt ggctaccttc
    29221 acacttgctg ttaaccgtac ctttaaaagc caaaatggtg aacgcgaggc agatttcatt
    29281 aactgtgtga tctggcgtca accggctgaa aatttagcga actgggctaa aaaaggtgcc
    29341 ttgatcggag ttacgggtcg tattcagaca cgtaactacg aaaaccaaca aggacaacgt
    29401 gtctatgtaa cagaagttgt tgcagataat ttccaaatgt tggaaagtcg tgctacacgt
    29461 gaaggtggct caactggctc atttaatggt ggttttaaca ataacacttc atcatcaaac
    29521 agttactcag cgcctgcaca acaaacgcct aactttggaa gagatgatag cccatttggg
    29581 aactcaaacc cgatggatat ctcagatgac gatcttccat tctagtcaga atggattgaa
    29641 cgaataccaa attatttgag ttcgggctaa aaatttagaa cttagaattt agatcaactc
    29701 cctaggaaat caagatttct tgccagtttt ctaaaattca gtcgtttttt aagagccctt
    29761 aacatcataa tttataaagg agaaaataca tggctcaaca gcgtcgtggc ggattcaaac
    29821 gccgtaaaaa agttgacttc atcgcagcta acaaaattga atatgttgat tacaaagata
    29881 ctgagcttct tagccgtttc gtttcagaac gtggaaaaat tcttcctcgt cgtgtaacag
    29941 gaacttcagc taaaaaccaa cgtaaagtaa caacagcaat caaacgtgct cgcgttatgg
    30001 ctcttatgcc ttacgtaaac gaagactaat aaacaaacag tccatttcgg actgtttttt
    30061 agttgactag gactagtcta ggcgtatagg tgagtttttt ctaaaagaga gaatgatagt
    30121 aaacgaaaat ccttgcgtag acagcaagga tgaaatgatt gttatttgtt aacaggtgac
    30181 atagtgtttt gaatgttgta tttgcgttgt aggtaatagc gtaaagcaag ggaaacacca
    30241 ccaataatga gcaaggcaag aggaggcaac tgtgggttaa gagaggttgg taaaaaggca
    30301 gttgcagagt acaaggcaat ccaaatcaac atggctaatg ataaggctgc gatgattttg
    30361 aaccaacttg gacgaaggct cttatctttt ccgagatgac ggtaaataaa gtaataagta
    30421 gcgtacatgg atgctcctcc accaaaacca agtgccagta aggaaatcaa tcctgtaact
    30481 gtagcgtttg tgttgaagaa ggtcatgatg ccatttaaaa gggcaacaat tccgatgaat
    30541 agcaaagagg tatctagcca catcaaccaa ggattggtgt ttttgtcagt ttctgctgct
    30601 ctttgactag ggtcttggct aaaagaagct gcccaagcag tcggagtgcc taatagattt
    30661 cgagcggtga cacctttttt ctggttttct agaatagctg gaatagcttc ttcgagaatc
    30721 agcttaatgt cctcatcaga cttgccgtct tggattaatt tgttcgtagc ggtgtggata
    30781 aattcttgat tttttttggt aagttcttgt aattccatgg gaatcccttc tttatatggg
    30841 ttagttaaag taagtcaatg gtattagcta gtttcaaatg agactttgga gccagtcgtt
    30901 tgacacagag ttttgtcagg tgttaaccgc attctgcagc ttgctccact ctagaaccat
    30961 ttttttctaa taaagtaaat cacaacaaag gaactaagga gcatagcaat caaggtaata
    31021 taccaaaaag catgttctag gccatttagt ggtaaccagt tgttttggaa attcatacca
    31081 taggcggaga aaatcacagt tggtatatct aaagccatgg tcatcaaggc caatgttttc
    31141 ataatggtgt tctggttatt gttgataatg gaagcagtgg tttcagtcat ggcattcaag
    31201 acattttcat aaatgccagc catctcaatg gcctgttggg tttcaatcaa ggtatcttct
    31261 agcaaatcct cgtcctcaat gtatttcttg agagagcttg ttgagctgga taatttcttg
    31321 acgatgcgtt cgttgaattt caaggaagcc tttaagtaga caatggattt ttcaagttcc
    31381 atcatgtcga taagttcttc atttcgagta gctgcttcaa gctgagcttc caaacgttcg
    31441 ctttggcgat caatggtcct caaggcagtc agaaagagct cggcgttgcg atatagaatc
    31501 tgaaaaacaa aacgtgtctt catgaaggta tagaaatttt tgacccggcg gttgtgaaaa
    31561 tgatcgaaaa gggtcatgtc atgcagacaa gttgtgataa cagcattttc cgttacaata
    31621 atgcctaaag gcatagtaat atagtaactt ttattgttac gttcttcgta tatcgggacg
    31681 tctacgataa ttagggtata atcatcttct acggcaatac gtgaggtttc ttccacgtcc
    31741 aaaggggcgc gcaagtcaga aatatcaatg ttgaattgat cggcgatctt catagactct
    31801 tcttgggaag ggttaaccag tttaatccaa gctcctggct cgaatgtttc tatttctttg
    31861 aattcaattg ccgatgaaag aaacatttgt ttcatgacaa gccctccttt ttgatgattg
    31921 actggtagag attgacatca aaccttgata ataaagcctt ctcaaggatt ttctgaaaaa
    31981 ttctcaatac ttatctatta taccaaaatt cgcaaagttt ggggcaatag gttatcagaa
    32041 atttttgtta taatataaga aagctcgatg aggagggtgc ctttaggcac attcaagatg
    32101 caaaataaaa taataattca tggggcaaga gcccacaatt taaaaaatat tgacgtggaa
    32161 attccacgag acaaattagt tgtcgtgaca gggttatcag ggtcaggaaa atctagtcta
    32221 gcctttgata ctatttatgc ggaagggcaa cgtcgttacg tagaaagttt atcagcttat
    32281 gctagacagt tcttgggtaa tatggaaaaa ccagatgtgg attccattga cggtcttagc
    32341 cctgctattt ccattgacca aaaaaccacc agtaagaacc ctcgctcaac ggttggtacg
    32401 gttacggaaa tcaatgatta tttacgttta ctatatgcgc gtgtgggcac accttactgt
    32461 atcaatgggc atggtgctat cacggcgtct tctgcagaac aaattgtaga gcaggtctta
    32521 gccctccctg aacggacacg catgcagatt ttagctcctg ttgttcgtcg gaagaagggg
    32581 caacacaaaa cagtttttga gaaaattcaa aaagacggct atgtccgtgt gcgcgttgac
    32641 ggggatattt ttgacgtgac aggagtacca gagttgtcca aaagtaagat gcacaacatt
    32701 gaggtggtta ttgaccgtct ggttaataag gatggtattc gtagccgttt atttgattcg
    32761 gttgaagcag ctttaaggct gggagatggc taccttatga ttgacactat ggatggcaat
    32821 gaactgctct tttctgagca ttattcctgt cctgtctgtg ggtttacggt tcctgaatta
    32881 gaaccaagac tcttctcttt taatgcgccg ttcggctctt gtccgacctg tgatgggcta
    32941 ggcattaagt tggaagtgga tttggacttg gttgttcctg acccaagtaa gtctttgaaa
    33001 gagggagctt tggcgccttg gaatcctatt tcctccaatt attacccaac catgcttgag
    33061 caagctatgg caagttttgg ggtggatatg gatacacctt ttgaggcctt gactgaggaa
    33121 gaaagggatt tagttcttta tggttcaggg gatagagaat ttcattttca ctatgtgaat
    33181 gattttggtg gtgagcgtaa cattgacatt ccttttgaag gtgttgtgac taatgttaat
    33241 cgccgttatc acgaaactaa tagtgattat acgcgcaatg tgatgcgtgg ttatatgaac
    33301 gaattgacct gtgcgacttg tcatggttac cgtttgaatg accaagcctt gtgtgtgcat
    33361 gtgggtggcg aagaaggacc tcatattggt caaatttcag aattatcgat tgccgaccac
    33421 ttgcagttgt tggaagaact ggaactcaca gaaaatgaaa gtaccattgc taaaccgatt
    33481 gtcaaagaaa ttcatgaccg cctgaccttc ttaaataatg tgggactgaa ttatctgacc
    33541 ttatcacgtg ctgctgggac tttatcaggt ggggaaagtc aacgaatcag gttagcgaca
    33601 cagattggtt ctaacttatc aggggtgctc tatatcttgg atgagccttc tattggattg
    33661 caccaaagag acaatgaccg tttgatcgaa agcctgaaaa aaatgcgtga tttgggtaat
    33721 accttaattg tggtagaaca cgatgaagac accatgatgc aggcagactg gctgattgat
    33781 gtggggcctg gggcaggtga gttcggtgga gaaattattg cctctggaac gccgaaacaa
    33841 gtggctaaga ataaaaaatc catcacgggt caatatttgt ctggaaaaaa attcattcca
    33901 gtgccattag agcgtcgttc tggtaatggg cgattcattg aaataaaagg agcagcgcag
    33961 aataatcttc aaagcctcga cgtgagattc ccactgggta aatttattgc ggtcacaggg
    34021 gtatcaggct cagggaaatc aaccttggtt aatagtattt tgaaaaaggc tgtcgcccaa
    34081 aaattaaacc gtaatgctga taagcctggt aaatatcact ctatttctgg tattgaacat
    34141 attgaacgct tgattgacat tgaccaaagt ccgattggaa ggacgccacg gtcaaatcca
    34201 gccacctata cgggtgtctt tgatgatatt cgagacttgt ttgcccaaac caacgaagct
    34261 aagattcgtg gctacaaaaa aggccgtttc tcttttaatg tcaaaggtgg gcgttgtgag
    34321 gcttgttcag gtgatgggat tatcaaaatc gaaatgcact ttttgccaga tgtttatgtg
    34381 ccttgtgagg tttgccacgg cagacggtat aattctgaga cgcttgaggt gcattataaa
    34441 gaaaaaaata ttgctgaagt gcttgacatg actgtcgatg atgccttggt atttttctct
    34501 gctatcccta aaattgcccg aaaaattcaa accattaagg atgttggttt gggttatgtg
    34561 accttgggtc aaccagctac tactctatct ggaggagaag cgcagcggat gaaattagct
    34621 agtgaattgc acaaacgctc gacaggtaag agcttgtata tcctagatga gccaacgact
    34681 ggtttacaca cagatgatat tgcaaggcta ttaaaagttt tggaacgctt tgtagacgat
    34741 ggtaatacgg ttcttgtgat tgagcataat ttggacgtta tcaaatctgc tgaccatatt
    34801 attgacttag gaccagaagg tggtgtcgga ggtggtcaaa ttgttgccac ggggacacca
    34861 gaagaggtag ctcaagttaa agaaagctat actggtcatt atttgaaagt aaaactacaa
    34921 caataggatt aggagttcgt ttgagctcct ttttaatctt ttaaatgctc tcaaaccatg
    34981 gtaaacttaa agtagttttt tcatgctaca atattctcaa aagttaccaa aggagttcgc
    35041 gatgtcagga tttttagagc aacgattagg tcactgccta aggcagatgg cagagaaggg
    35101 gctagaggct cttctagtca cccatttaac caatagttat tacttgacag gtttttctgg
    35161 aactgcagca actgttttga taacggccaa acgtcgtgtt ttgatcacag attcacgtta
    35221 taccttgctt gctaaagcta gtgttgaggg atttgatatt atcgaaagcc gcacgcccct
    35281 gaaggttgtg gcagaattgt taggggctga tcaaatagat tgccttggtt ttgaggacca
    35341 ggtatcgttt tctttttatc aggccatgca agcagaactg tcaggaataa ccttgcttgc
    35401 tcagtcaggc tttgtggagc atttacgtct tattaaggac gtctctgaaa ttgagaccat
    35461 tgctaaagcg tgctcgatct cagacaaagc atttgaagat gctcttgatt ttattaaacc
    35521 agggacaacc actgaacgtg acctggctaa ttttttagat tttcgcatgc gtcagtatgg
    35581 tgccagcggc acatcatttg atatcattgc agcttcaggc tatcgctctg ccatgcctca
    35641 tggacgcgcc agtgacaagg ttatccagaa taaagagagc ttgaccatgg actttgggtg
    35701 ttactacaat cactatgtta gtgatatgac gaggaccatt cacattggcc aagttactga
    35761 tgaagaacgt gagatttatg ctcttgttct tgctgctaat aaggctctaa ttgctaaagc
    35821 tagcgctggc atgacttata gtgactttga cggtattccg cgccaactta tcactgaggc
    35881 gggttatggc agtcacttca cacatggcat tggtcatggt atcgggcttg acatccatga
    35941 gaatccattt ttggggaaat ctgagcaact tctccaagct ggaatggtgg tcacagacga
    36001 gccaggtatc tatttggata acaaatatgg tgtccgtatt gaagatgact tggttatcac
    36061 aaaaactggt tgtcaagtct tgaccttggc acccaaagaa ttaattgtat tgtaaaagaa
    36121 tggttcagga aaggattagg ggagaagcaa tgacaaatcg tttatcatgg caagactatt
    36181 ttatggccaa tgcagagctg atttccaagc gctctacctg tgatcgcgcc tttgtgggag
    36241 ctgttttggt aaaggataac cgcattattg ccacaggtta caatggcgga gtttctgcta
    36301 cggataactg caacgaagcg ggtcattata tggaagacgg tcattgtatt cgcactgttc
    36361 atgctgaaat gaatgctttg attcaatgtg cgaaagaagg aatttcaacg gacggaactg
    36421 aaatttacgt gactcatttt ccttgtatta actgcactaa ggcgcttttg caggcgggga
    36481 ttacaaagat tacctataaa gcacattacc gtccgcaccc ctttgccatt gaactgatgg
    36541 agaaaaaagg ggttgcctat gtgcaacatg atgtgcctca aattgtttta ggaggcgata
    36601 aggaacaata gaaagtgtac ctaaaaggac ggtcataaaa gatttgagcc aaggccactt
    36661 ttgtggtaaa atgaagtgat aaatatttta gtaagaggta ataataatga ttgaagcaag
    36721 taagcttaaa gcaggtatga catttgaagc agaaggaaaa ttaattcgtg tccttgaagc
    36781 tagccaccac aaaccaggta aaggaaacac tatcatgcgt atgaaactac gtgatgtgcg
    36841 tacaggttct acttttgaca caacttaccg cccagatgaa aaatttgagc aagccatcat
    36901 tgaaactgtc ccagcacaat acctatacaa aatggatgac actgcttact tcatgaacac
    36961 tgatacttat gatcagtacg aaattccagt tgctaacgtt gagcaagaat tgctttacat
    37021 tcttgaaaac tcagacgtga aaatccaatt ttatggaagt gaagtgattg gggtaacggt
    37081 tccaacaact gttgaattga ccgttgcgga aacacaacca tctattaaag gagcgacagt
    37141 gacgggttca gggaaacctg caactcttga gacaggactt gttgttaacg ttccagactt
    37201 tatcgaagct ggccaaaaac taatcattaa cactgcagaa ggtacttacg tttctcgtgc
    37261 ttaatccttt gtcaaaacag attagtctaa aaaagagaaa ggaaatgcta tgacaactga
    37321 atatatcggt gaaatcgtca tttcaccacg agtgcttgag gttattacgg ggattgctac
    37381 gacacaagtt gagggcgtcc actcactcca taacaagaaa atggcagata gctttaacaa
    37441 agcaagtctt ggtaaagggg tttatctcca gacagaagaa gatggaagtg ttacagcaga
    37501 tatttatgtt tacttgcaat atggagtcaa ggtcccgact gtatctatga atattcaaaa
    37561 aacagtcaaa tctgctgtgt acgatatggc agaagtgcct atttctgcag ttaatatcca
    37621 tgttgaaggt attgttgcgg aaaagacacc aaaaccagat ttgaagtcac tttttgatga
    37681 ggatttcttg gatgactaac agctttcaaa attcaagaag agatttgcgt gaacgtgcct
    37741 ttcaggcttt atttaacata gagatgggag ctgagttatt ggcagcttct cagtttgcct
    37801 atggttatga taaagtaaca ggggaggacg ctcaagtatt ggagctgccg atttttttat
    37861 taagtcttgt aacgggtgtc aataatcata aagaagagtt ggataacttg atatcaactc
    37921 atttgaaaaa aggttggtcg ttagaacgct tgacactaac agacaaaacg ttattacgac
    37981 taggtctttt tgaaatcaag tattttgacg aaacaccaga ccgtgttgca ctaaacgaaa
    38041 tcattgaagt agctaaaaaa tattctgatg aaacctctgc taaatttatt aatggcttac
    38101 ttagccaata tgtctcggaa gctccttcag caaataaatc ataataagtc ggagcaatct
    38161 taggattgta tccgattttt tcaatttatg tacgaatatt aaaagacaaa caagcatact
    38221 ctcgcatcta gaaagagtat gcttgtttgt cttttagagt aattagtgat tggttatgtt
    38281 ttgtttaaat acttgctcct ggaagtagcg taatcggtaa aatatagtct ttactggttt
    38341 tttctttttt aatttttttg atgagtattt cgacactcaa tttagcaatc tcatcaatag
    38401 gttgacgaat ggtcgctaat tgaggaacat attgctggat aaatgtcgtt ccatcataac
    38461 ctatgacttt catatcctct ggaatagtaa tgtgaagttg tttggctact ttcataatga
    38521 ggatagcagt taaatcatca gaaacgaaaa ggccatcagg ttttcgggtt gccaaaatgg
    38581 atttaatttc catttcgcgt ctaacaggag ataggttatt tggtaatttg aggatttctg
    38641 cacttcgttt gagctggtag ttaaacccta gctggcgcaa ccctgtgggc gaatcagaat
    38701 tgtcattacc tgtaatcatg acaatgtttt gacaaccgtg tttttgcaaa gtttgtgcgg
    38761 ctaatttacc accttcaaaa ttatctgaag aaataaccgg gatatttggc gccagattac
    38821 ggtcaaaagc tacaatagga gcttcgacac gctcataatc ctcaattccc aaattatgac
    38881 tggaagaaat aatgccgtcc acttgattgg ccgcaagcat ttctaagtat tcgcgctctt
    38941 tgacgggatt atgttcacta ttgcaaataa tagttttgta gccctgttta aacaattcaa
    39001 tttccaaatg ttcaattaat tcagcgtaaa agatattgct aatgttgggg aagataagcc
    39061 caatgagttg ggttgattta ccttgcaaac ttctagcgag attgttaggc ttgtagccca
    39121 attcacgcat ggccttattc accttattca ctgttttttg ggaaaggtag ccttttttgt
    39181 tgattactcg cgaaacagtt gttggactga cacccgccaa ggctgccacg tctgttaatt
    39241 ttgcgaccac ttgcctaata cctcatttca taataatgtc caaaagcttg tccttctact
    39301 acttggatac ctgtttgtcc ttgggttggg aaaacacgac tcgttaggac tttttgccct
    39361 tggttaataa agatttcaag aatggaattg tccacataga cattaagtgt aacatggcct
    39421 tgtgggattt ggcaagagcg caccgtacca tagtcttggg catattgaac ccctgcccga
    39481 cttcggtcaa tgcttaactg tccttttgtt gtatccactt tcaatcttag gccattccct
    39541 ttttggtcag caaataggag caggtcaagc tttttttggc ctggaatcgt caattccaat
    39601 tcataacagt tagaactgtc tattttatta tgaaataatt ctgctggccc tcgaagattt
    39661 tgtagagctg aaacaggtgt ttgatagaga attccgtctt taatccttaa ttctttcact
    39721 aaactaagag ctccttgata gttataacga tctgtcggat aatcaatatc tggtaaccca
    39781 atccaagaca cggctagaac cctgccatct ggactactaa aggcttgagt ggcataagct
    39841 tcaaaaccaa agtcaagatt ttgaagggcc cccccaccca gcaattggcc agtttctgga
    39901 ttgaagcttt caaaaatttt ataggtattg gggtagatat tttgataatc taaatcagct
    39961 ttagccagtc cttgtgggct gaaaatcaaa acaggtttgt catcgacaaa cacaaggttg
    40021 gggcattcaa tcatgtattc cgtaccagaa tcgtcaaagt ccaaatcggc tataaatcgc
    40081 cagttgtcca catgattgtc cacagctttg taaagtttga tttttccttt gccatctaaa
    40141 ccttgggcgc caataatagc atagaattga ccttgataag aaaaaagctg aggatcccga
    40201 aaatgttctg taacatcatc gggctgttca atcaaaacct gcgggatttt ggaaatattt
    40261 ccttgtttat ccatccatgc gccaacctgt aatggtgttc tgacccagtt ggcattgcga
    40321 acattaccag tgtaaaagag gaagagcttg tcatcaatag cataggcaga acctgagtaa
    40381 gccccatgac tatcgtgagc gtggtctggc agaaggcggc tccttgtttc cgtaaaatgg
    40441 acgaggtctg tggatgtcat gtgtacccat tgtttcagac catgcgcagc gccataaggc
    40501 cagttttgat aaaaaagatg gtagcgaccg ttgaaataag aaaacccatt ggggtcattg
    40561 agtaatcctg tcttaggttc aacatgaaat tggctgtgcc atggggattg ggccattttt
    40621 tcagtaatag cttggtagtc ttttgagctc cactctttgt aagggcggta gcgaatagct
    40681 tgtggtagat ccatcaaaat ctccttgttt tatagtcgtc ttcaagaata tactaaacgt
    40741 tttctgttta aaaatcaaga atttaaaaca tataaaataa aaatatgtta aacgcttgac
    40801 ataaaaaata ttagtgataa aatgatagtc aagaagtgaa gcggattcac tagcgttggt
    40861 cctacacatt cttagccaca aagctggcag aatggatgag ggactaacac caaatgaaaa
    40921 aggagacttt taggcatgga taatcgtcag attgcaactg aagtgattga ggctttaggg
    40981 ggccgagaaa atgtgaggag tgttgcccac tgtgcaaccc gccttcgagt aatggttcat
    41041 gacgaaggaa agattgacaa ggaaaaagca gaagctattg acaaggttaa aggagctttc
    41101 tttaattctg gtcaatatca aatgattttt ggaactggta ccgttaataa catttatggc
    41161 gaagttgttg ctcttggttt acccacgtca tcaaccagtg agcaaaaagc agaagcaggc
    41221 aaacaaggca atatcttcca acgggccatt cgtacgtttg gagatgtctt tgttcccatt
    41281 attccagcta ttgtagcaac gggtctcttt atgggggttc gtggtttggt gacccagcca
    41341 gctattatgg atttatttgg ggtgcatgag tacggggaaa attttctcat gtacactcgt
    41401 attctaacgg atacagcctt tgtctacttg ccagctttgg tggcttggtc agcctttagg
    41461 gtctttgggg gtaatcctat tatcggtatt gttttaggct tgatgttggt gtccaatgaa
    41521 ttgccaaacg cctgggtagt tgcctctggt ggagatgtta agccgctaac cttctttgga
    41581 tttgttcctg ttgttggtta tcaaggtacc gttttacccg ccttctttgt tggtctggta
    41641 ggagctaagt tggagaaatg gttgcacaaa aaggttccag aagctttgga cttattggtc
    41701 acaccgtttt taacgtttgc tattatgagt atcttgggac tatttgtgat tggaccagtc
    41761 ttccattctc ttgaaaacct tgttctggct gggacacagg ccgtcttgca tttgccgttt
    41821 ggcattgctg gtcttattgt tgggggaatc caacaattaa tcgtagtgac tggtattcac
    41881 catatcttta acttcctaga agcgcagcta attgccaata ccggaaaaga tcctttcaat
    41941 gcttacctaa cagcagcaac agctgctcaa gctggagcta ccttagctgt tgctgttaaa
    42001 accaaatcac caaaattaaa aggtttggct tttccatcga ccttatcagc tcttttaggg
    42061 attactgaac cagctatttt tggggtcaat ctccgttatc caaaagtctt tgtttcaggt
    42121 cttattggtg gtgccttagg tggttgggtc gctggactct ttggcattgc aggaactggt
    42181 tttgggatta cggtcttacc aggaactctc ctttacttga atggccaatt attgcaatac
    42241 cttgtgacta tgcttgtcgg tcttgggtta gcctttgcaa ttgcttatac ttggggttat
    42301 caagatagag aaacccttcc gttaccagct gtcgaagttg atcaaacggc tgatcagcca
    42361 gccttagcag aggaaacttt atatagtcct ttgaatggaa cagttgtaga tttagcagct
    42421 gtttcagacc ctgttttttc atcaggtgct atgggtcaag gcttagcaat taagccagaa
    42481 gataataccc tatactcacc agttgatggt aaagttgaaa ttgtctttga aacaggtcat
    42541 gcctatgcta taacgtcaag tcaaggagca gaagtgttac ttcatattgg tattgatacc
    42601 gtgtcgatgg caggagatgg ctttgaatct cttgtagcag taggtcaggc ggttaaaaaa
    42661 ggtgatcttc ttggacactt tgatcctagc aagattgcag aagctggact agatgacacc
    42721 accatgatga ttgtgaccaa tagcgctgac tatcaaagcg tggacattct tgctcaagga
    42781 catgttttga ttggtgatca agtagcactt atcaaataag gacaaaagag ctaactaagc
    42841 agctcttttg tcctgccatg aatggcaggt tggcaaaaaa atgagaaaag cctaaaaacc
    42901 ttaaatttgt gttattttac ctatactttg taccttgttt tttttaataa agtgttgtta
    42961 tacttaaggc gaactatagg aatgcgctta catagatggt atatcaactg ggaagccatg
    43021 acttagtacc aaaaataagg agtgtccaaa tggataaaca tttgttggta aaaagaacac
    43081 tagggtgtgt ttgtgctgca acgttgatgg gagctgcctt agcgacccac catgattcac
    43141 tcaatactgt aaaagcggag gagaagactg ttcaggttca gaaagaatta tcttctatag
    43201 atagcttgca ttatctgtca gagaatagca aaaaagaatt taaagaggag ctttcaaaag
    43261 aaaaagtacc agaaaaggtc aaagagatat tagcaaaagc tcagcaggca gataaacaag
    43321 ctcaagaact taccaaaatg aaaattcctg agaaaatacc gatgaaaccg ttacatggtc
    43381 ctctctacgg tggttacttt agaacttggc atgacaaaac atcagatcca acagaaaaag
    43441 acaaagttaa ctcgatggga gagcttccta aagaagtaga tctagccttt attttccacg
    43501 attggacaaa agattatagc cttttttgga aagaattggc caccaaacat gtgccaaagt
    43561 taaacaagca agggacacgt gtcattcgta ccattccatg gcgtttccta actgggggtg
    43621 ataacagtgg tattgcagaa gataccagta aatacccaaa tacaccagag ggaaataaag
    43681 ctttagccaa agctattgtt gatgaatatg tttataaata caaccttgat ggcttagatg
    43741 tggatgttga acatgatagt attccaaaag ttgacaaaaa agaagataca gcaggcgtag
    43801 aacgctctat tcaagtgttt gaagaaattg ggaaattaat tggaccaaaa ggtgctgata
    43861 aatcgcgtct gtttattatg gatagcacct acatggctga taaaaaccca ttgattgagc
    43921 gaggagctcc ttatattaat ttattactgg tacaggtcta tggttcacaa ggagagaaag
    43981 gtggttggga gcctgtttct aatcgacctg aaaaaacaat ggaagaacga tggcaaggtt
    44041 atagcaagta tattcgtcct gaacaataca tgattggttt ttctttctat gaggaaagag
    44101 caggcagcgg caatctttgg tatgatatta atgtagaaga tgagtctaat ccaaatattg
    44161 gtaaagaaat taaaggaacg cgtgccgaac ggtatgccaa atggcaacct aaaacaggtg
    44221 gggttaaggg aggaatcttc tcctatgctg tggatcgtga tggtgtagct catcctaaaa
    44281 agaatggtta taaaaatcca aagttggata atatagtaac atcagattat agtgtctcca
    44341 aggcattaaa gacagttatg ctaaaagata agtcgtatga tctgattgat gagaaagatt
    44401 tcccagataa ggctttgcga gaagctgtga tggcgcaggt tggaaccaga aaaggtgatt
    44461 tggaacgttt caatggcaca ttacgattgg ataatccagc gattcaaagt ttagaaggtc
    44521 taaataaatt taaaaaatta gctcaattag acttgattgg cttatctcgc attacaaaac
    44581 tcgaccgttc tgttttaccc gctaatatga agccaggcaa agataccttg gaaacagttc
    44641 ttgaaaccta taaaaaagat aacaaagaag aacctgctac tatcccacca gtatctttga
    44701 aggtttctgg tttaactggt ctgaaagaat tagatttgtc aggttttgac cgtgaaacct
    44761 tggctggtct tgatgccgct actctaacgt ctttagaaaa agttgatatt tctggcaaca
    44821 aacttgattt ggctccagga acagaaaatc gacaaatttt tgatactatg ctatcaactg
    44881 tcagcaatca tgctggaagc aatgaacaaa ccgtgaaatt tgacaagcaa aaaccaactg
    44941 ggcattaccc agatacctat gggaaaacta gtctgcgctt accagtggca gagggaaaca
    45001 ttgatttgca aagccagctt ttgtttggga ctgtgacgaa tcaaggaacc ctaatcaata
    45061 gcgaagcaga ctataaggct taccaaaatc ataaaattgc tggacgtagc tttgttgatt
    45121 caaactatca ttacaataac tttaaagttt cttatgagaa ctataccgtt aaagtaactg
    45181 attccacatt gggaaccact actgacaaaa cgctagcaac tgataaagaa gagacctata
    45241 aggttgactt ctttagccca gcagataaga caaaagctgt tcatactgct aaagtgattg
    45301 ttggtgacga aaaaaccatg atggttaatt tggcagcagg cgcaacagtt attaagagtg
    45361 aaaatgatga aaatgccaaa aaagttttta atggcatcat ggaatataat cctttatcgt
    45421 ttaacaataa atcttcgatt atctttgaaa tgaaagaccc tagtttagca aaatattggc
    45481 gccttttcaa tgatagcagt aaaggcaaag acgactatat caaagaagca aaacttgaag
    45541 tctttacagg ccagctgaat gctgaagcag atgtgaaaac gagcttggaa aaatcagatg
    45601 attggcaaac tgtttcaacc tattcaggac aagaacaggt atttagccat gcactggata
    45661 atattagtgc taagtactgg agaataacag ttgacaataa gaaaaatcaa tatggatgtg
    45721 tttcactccc tgaactccaa attttaggtt atccgttacc taacgccgac actatcatga
    45781 aaacagtaac tgctgctaaa gagttgtctc aacaaaaaga taagttttct caaaagatgc
    45841 ttgatgagtt aaaaataaaa gagatggctt tagaaacttc tttgaacagt aagatttttg
    45901 atgtaactgc tattaatgct aatgctggag ttttgaaaga ttgtattgag aaaaggcagc
    45961 tgctaaaaaa ataaacaaag caactctctt agatagcaac attcagatta aattaacaaa
    46021 atgtgactat gataaaggtt tgctggaatt gattaaccaa aagactaaaa atctgagatg
    46081 aatagtccca gatttttagt cttttatagg ttttgatgac ataaagctaa ataatcgtta
    46141 gactaccaga aagtggcgct tgtccgtgag acatggctgt cttgataaga gcctgtgtca
    46201 tcataaagat aaaaaagaac aagaaaaagg agaaaacatg ggaaaattat atggaagtat
    46261 tgaagctggt gggacaaagt ttgtctgtgc cgtgggtgat gaggagttta cagtggtgga
    46321 taaaacacaa tttccgacca ccacaccaga agaaaccatc gcgcaaacca tcgcatattt
    46381 taaaaccttt gaggccgatt tggctggaat ggcgattggt tcttttggac caattgatat
    46441 tgatccgtcg tcagagactt acggttatat cacaaccact cctaagtcag gctgggctaa
    46501 tgtggatttg ttaggacaac tttcggctgc ttttaagatt ccttttgatg tgacaacaga
    46561 tgttaatagc tctgcttatg gtgaggtgct tgctcgtcct ggtgtggaaa gtttggtcta
    46621 ttacaccata ggtactggta ttggggcggg agctattcaa catggccact ttattggggg
    46681 attaggtcat acagaagcgg gtcataccta tgtcatgctc catcctgatg atatggccaa
    46741 gggattttta ggtgtttgcc cttttcataa agggtgtctg gaagggatgg cagcaggtcc
    46801 aagtattgag gccagaacgg gagtgagagg tgaacggctt gatcaggaag ctgatgtttg
    46861 ggacattcaa gccttctaca ttgcccaagc agcgctgcaa gcaaccatgc tttaccgtcc
    46921 tcaagcgatt gtttttggcg gaggtgtcat ggcgcaagaa catatggtgt tgcgcgtgca
    46981 tgataaattc actacccttt taagcggtta tttgccagtc cctgatttga cagactacat
    47041 tgttactcca gctgttgttg ataatggctc cgctactctg ggaaattttg ctttggccaa
    47101 gttggctgca caaggaaaat agggtctatt tttgcctgct tgtctagtaa aagaaagcgc
    47161 agtcagctag aacatgctat aataaacaga gatcaacatc agaagcgagg aatattatgt
    47221 cagaaccatt atttctaaaa tcaaccatgc acgacaggat ttggggtggc accaagttga
    47281 gagatgtctt tgcttacaac atcccaagtg acaccacagg tgagtattgg gctatttctg
    47341 ctcatcctaa tggtgtttcg acagttacta atggacgtta tcaaggacaa cctttaaaca
    47401 cattatatgc gcaagagccg gccttgtttg ggaatccaaa ggaagaagtt tttccactgt
    47461 taactaagat tttagatgct aatgactggc taagtgtcca agttcatcct gatgatgctt
    47521 atggacatga acatgaagga gaattaggca agacagaatg ctggtatatt atttctgccg
    47581 aagagggttc tgaaattgta tacggccatc aggccaagtc caaagaagac cttcgtgcca
    47641 tgattgaagc aggcgcttgg gatgatttgc tgactcgtgt cccagtcaaa gcaggcgatt
    47701 ttttctatgt tccaagcggc accatgcatg cgatcggcaa gggaattctt attttagaaa
    47761 cccagcagtc atctgatacc acttatcggg tttatgattt tgaccgtaag gacgttaatg
    47821 gtaatcttcg tgaccttcat attgaaaagt ctattgatgt cttaacgatt ggtaagccag
    47881 aaaatagcgt gccagccact atggttttgg ataatatggt agcaacaact ttagtctcaa
    47941 cgccattttt cactgtttac aaatgggtaa ctagtcaaat ggttgacatg aaacaagctg
    48001 cgccttatct tttagtgagt gttttaaaag gtcaaggaaa actctatgtg gaccagaagg
    48061 cttatgagct agaaaaaggc atgcacttta tcttgcctaa cgatgttaaa tcgtggtcat
    48121 ttgatggtca attagaaatg attgtgagtc accccaatca actcgtttaa taccatggta
    48181 tcaatatgag aaaaaaggat aaaattatga ctctctgttt ctctgataac ttta
//
LOCUS       DAUCXI010000011        47729 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.011, whole genome shotgun sequence.
ACCESSION   DAUCXI010000011 DAUCXI010000000
VERSION     DAUCXI010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47729
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.011"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(56..286)
                     /locus_tag="VGY43_000620"
     CDS             complement(56..286)
                     /locus_tag="VGY43_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEQ4301833.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
     gene            complement(350..1417)
                     /locus_tag="VGY43_000621"
     CDS             complement(350..1417)
                     /locus_tag="VGY43_000621"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEQ4301834.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            complement(1495..3954)
                     /gene="parC"
                     /locus_tag="VGY43_000622"
     CDS             complement(1495..3954)
                     /gene="parC"
                     /locus_tag="VGY43_000622"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEQ4301835.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPPGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKEADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLKVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            complement(4045..5994)
                     /gene="parE"
                     /locus_tag="VGY43_000623"
     CDS             complement(4045..5994)
                     /gene="parE"
                     /locus_tag="VGY43_000623"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEQ4301836.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEVLSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGAVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTIAERLKESAFLLKNVKMSLTDLRGDE
                     PIVEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDHDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVDSIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVETGHVYIALPPLYKMSKGKGKTEKIAYAWTDGEL
                     EDLRREFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
     gene            6129..6770
                     /gene="plsY"
                     /locus_tag="VGY43_000624"
     CDS             6129..6770
                     /gene="plsY"
                     /locus_tag="VGY43_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEQ4301837.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLTFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            complement(6828..8096)
                     /locus_tag="VGY43_000625"
     CDS             complement(6828..8096)
                     /locus_tag="VGY43_000625"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEQ4301838.1"
                     /translation="MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLIAGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFA
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(8228..8881)
                     /locus_tag="VGY43_000626"
     CDS             complement(8228..8881)
                     /locus_tag="VGY43_000626"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEQ4301839.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESSHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK"
     gene            complement(9014..9664)
                     /locus_tag="VGY43_000627"
     CDS             complement(9014..9664)
                     /locus_tag="VGY43_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ4301840.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLALLGR
                     SHQPLLHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWIIAFLLERYQEFLENKLALV"
     gene            complement(9693..10556)
                     /locus_tag="VGY43_000628"
     CDS             complement(9693..10556)
                     /locus_tag="VGY43_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ4301841.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWDTIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMVKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DVQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDK
                     KIPVIDTKDVN"
     gene            complement(10674..12128)
                     /locus_tag="VGY43_000629"
     CDS             complement(10674..12128)
                     /locus_tag="VGY43_000629"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEQ4301842.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGKPFAGVPIFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVK
                     RLEALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGIS
                     ALATASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKDSIYQSLQRSLTIGFYQRLSDGSPVSLDTAKALRQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LPMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(12325..12954)
                     /locus_tag="VGY43_000630"
     CDS             complement(12325..12954)
                     /locus_tag="VGY43_000630"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEQ4301843.1"
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(13012..13704)
                     /gene="pyrF"
                     /locus_tag="VGY43_000631"
     CDS             complement(13012..13704)
                     /gene="pyrF"
                     /locus_tag="VGY43_000631"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEQ4301844.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQG
                     PDIVRSIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            complement(13981..14517)
                     /locus_tag="VGY43_000632"
     CDS             complement(13981..14517)
                     /locus_tag="VGY43_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301845.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     PAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDLLYEHIQRVNLEE
                     EAFIKYYQGPKVPTGEFE"
     gene            14739..15644
                     /locus_tag="VGY43_000633"
     CDS             14739..15644
                     /locus_tag="VGY43_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ4301846.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHNKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            complement(15724..16512)
                     /locus_tag="VGY43_000634"
     CDS             complement(15724..16512)
                     /locus_tag="VGY43_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEQ4301847.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRTIEDQYHCSLWINQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWQFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(16505..17218)
                     /gene="deoD"
                     /locus_tag="VGY43_000635"
     CDS             complement(16505..17218)
                     /gene="deoD"
                     /locus_tag="VGY43_000635"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ4301848.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVGLETLIAND"
     gene            complement(17884..18693)
                     /locus_tag="VGY43_000636"
     CDS             complement(17884..18693)
                     /locus_tag="VGY43_000636"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEQ4301849.1"
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDTYTK
                     VYRDKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     gene            complement(18677..19117)
                     /gene="arsC"
                     /locus_tag="VGY43_000637"
     CDS             complement(18677..19117)
                     /gene="arsC"
                     /locus_tag="VGY43_000637"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HEQ4301850.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLADPILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSPYMKEDGESVNPIEVKGEKDVIDD"
     gene            complement(19136..20347)
                     /locus_tag="VGY43_000638"
     CDS             complement(19136..20347)
                     /locus_tag="VGY43_000638"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEQ4301851.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLSVPNMAKIGLGNISRPIPLKTIPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIFANMKEDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTA
                     MIGESFLGHLK"
     gene            complement(20424..21107)
                     /gene="rpiA"
                     /locus_tag="VGY43_000639"
     CDS             complement(20424..21107)
                     /gene="rpiA"
                     /locus_tag="VGY43_000639"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEQ4301852.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEAPKAG"
     gene            21485..23584
                     /locus_tag="VGY43_000640"
     CDS             21485..23584
                     /locus_tag="VGY43_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEQ4301853.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKERQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQTQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSGFNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVN
                     QTTAKKGISLTIADDAKAHLIDLGYNRAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILKEGQLVIRQNDQ"
     gene            complement(23642..24385)
                     /locus_tag="VGY43_000641"
     CDS             complement(23642..24385)
                     /locus_tag="VGY43_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301854.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(24533..25132)
                     /locus_tag="VGY43_000642"
     CDS             complement(24533..25132)
                     /locus_tag="VGY43_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEQ4301855.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDNKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(25142..26371)
                     /gene="clpX"
                     /locus_tag="VGY43_000643"
     CDS             complement(25142..26371)
                     /gene="clpX"
                     /locus_tag="VGY43_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEQ4301856.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQA
                     LLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            complement(26501..26671)
                     /locus_tag="VGY43_000644"
     CDS             complement(26501..26671)
                     /locus_tag="VGY43_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301857.1"
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLASLFLLNAFTNL
                     VNSIHAFYGTLF"
     gene            complement(26691..27188)
                     /locus_tag="VGY43_000645"
     CDS             complement(26691..27188)
                     /locus_tag="VGY43_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEQ4301858.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAIL
                     MGRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            complement(27268..28107)
                     /locus_tag="VGY43_000646"
     CDS             complement(27268..28107)
                     /locus_tag="VGY43_000646"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEQ4301859.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
     gene            28316..29491
                     /locus_tag="VGY43_000647"
     CDS             28316..29491
                     /locus_tag="VGY43_000647"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEQ4301860.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APVTEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQA
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIHLTGKFALTAIKEHRRIYHTNDKN"
     gene            29478..30755
                     /locus_tag="VGY43_000648"
     CDS             29478..30755
                     /locus_tag="VGY43_000648"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEQ4301861.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(30985..31974)
                     /locus_tag="VGY43_000649"
     CDS             complement(30985..31974)
                     /locus_tag="VGY43_000649"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEQ4301862.1"
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(31961..32974)
                     /locus_tag="VGY43_000650"
     CDS             complement(31961..32974)
                     /locus_tag="VGY43_000650"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEQ4301863.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPTIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGEN
                     DQP"
     gene            complement(32967..33911)
                     /gene="mvaD"
                     /locus_tag="VGY43_000651"
     CDS             complement(32967..33911)
                     /gene="mvaD"
                     /locus_tag="VGY43_000651"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEQ4301864.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSVSFLPDTATSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDQWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(33893..34771)
                     /gene="mvk"
                     /locus_tag="VGY43_000652"
     CDS             complement(33893..34771)
                     /gene="mvk"
                     /locus_tag="VGY43_000652"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEQ4301865.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLVIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            complement(35064..36296)
                     /locus_tag="VGY43_000653"
     CDS             complement(35064..36296)
                     /locus_tag="VGY43_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ4301866.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPDTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSMMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
     gene            complement(36305..36973)
                     /locus_tag="VGY43_000654"
     CDS             complement(36305..36973)
                     /locus_tag="VGY43_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4301867.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYC
                     LLEK"
     gene            complement(36976..37625)
                     /locus_tag="VGY43_000655"
                     /pseudo
     CDS             complement(36976..37625)
                     /locus_tag="VGY43_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
     gene            37845..39857
                     /locus_tag="VGY43_000656"
     CDS             37845..39857
                     /locus_tag="VGY43_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HEQ4301868.1"
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGAL
                     DNTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANS
                     ALLQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEH
                     EASHQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQ
                     NYEHYQFLDVAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQI
                     YPEHSIDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSAN
                     VVAVAPGIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNL
                     VTTAQLTIAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQM
                     TGQHIYDVLNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLT
                     TTYTVVVNDFLYGGGDGFSAFKKTKLIGAINTDTEAFITYITNLEASGKTVNATIKGV
                     KNYVTSNLESSTKVNSAGKHSIISKVFRNRDGNIVSSEIISDLLTSTENTNNSLGKKE
                     TTTNKNTISSSTLPITGDNYKMSPIMTILALISLGGLNAFIKERKS"
     gene            complement(39939..40349)
                     /locus_tag="VGY43_000657"
     CDS             complement(39939..40349)
                     /locus_tag="VGY43_000657"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ4301869.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            41067..41144
                     /locus_tag="VGY43_000658"
                     /pseudo
     CDS             41067..41144
                     /locus_tag="VGY43_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(41242..43119)
                     /locus_tag="VGY43_000659"
     CDS             complement(41242..43119)
                     /locus_tag="VGY43_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ4301870.1"
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSADVKAIQLIRQ
                     YELLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDTGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLENFLTNFAGPVITVSHDRYFLDKVATKILAFE
                     EGDIRVFYGNYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKRRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYDQLAQLQKELDQRNNDLLLAYERFEYLSGLD
                     I"
     gene            complement(43116..44324)
                     /locus_tag="VGY43_000660"
     CDS             complement(43116..44324)
                     /locus_tag="VGY43_000660"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEQ4301871.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLGRPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEATTFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDYHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKKMASLVEDLRKAQSLSVDMDR
                     INTLDQALVIHDKHDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            complement(44449..45297)
                     /locus_tag="VGY43_000661"
     CDS             complement(44449..45297)
                     /locus_tag="VGY43_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ4301872.1"
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            complement(45297..45677)
                     /locus_tag="VGY43_000662"
     CDS             complement(45297..45677)
                     /locus_tag="VGY43_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEQ4301873.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            complement(45924..46081)
                     /locus_tag="VGY43_000663"
                     /pseudo
     CDS             complement(45924..46081)
                     /locus_tag="VGY43_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051153.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            46580..47605
                     /locus_tag="VGY43_000664"
     CDS             46580..47605
                     /locus_tag="VGY43_000664"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEQ4301874.1"
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVT
                     PYHVTSVWTKGVTPTANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWLDQNNEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKA
                     FPGLSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGD
                     QSKLLTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSN
                     GNLKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQ
                     DSWNQTN"
BASE COUNT        14541 a         9794 c         8378 g        15016 t
ORIGIN      
        1 aacaaaaact attctatcat agtttttgta agctggcaag tgtttttgtc taattttaat
       61 ggttcaaatt gtagttttca atgatatttt caaccgcttg ttcgagcgtt ttgaagaagc
      121 aatctactcc atcatttttt aagacagcaa atttctcatc aagttctgca atttctccaa
      181 ccacacgttt accaatttgt aattgatagc catcaatctt agtctcatta accataactt
      241 tgtgatcaat cagttggatt tcaatttttt tatctttttt actcatcact ttacctcact
      301 ttgtctattt tacacaaaat caaaaaagct tgcaagagca agctctattt taatctactt
      361 ttacaatcca accttctggt gcttcaatat ccccaaattg aatgccgacc aactcatcgt
      421 ataaacggcg tgtcacagga ccaacttctg tttcactgta aaagacatgt aagttatcct
      481 tgtactggat accgccaatt ggagagataa cagctgctgt tccacaagct cctgcttcca
      541 caaatttatc caattcatta attggaacat caccctcaat tactgtcata ccaagtcttt
      601 cttcagctag ttgtaagagt gaatacttcg taatagatgg caagatggat ggactaagtg
      661 gcgtaacaaa ttcattattt gcagtaatgc caaaaaagtt tgcagctccg acttcttcaa
      721 ttttagtatg ggttgctgga tctaagtaaa tcacatcaga aaagcctgct gatttagcgg
      781 ccttacctgg tagcaaactt cctgcatagt ttcctcccac cttagcagca cctgttccgt
      841 aaggagcggc gcggtcaaac gcttcagaaa caataaaatt agttggagca agtccacctt
      901 tgaaatagtt tcctactggc atggcaaaaa tggtgaaaat atattcttcg gctggtttaa
      961 ccccaataat atctccaact ccaattaata acggtctcag gtaaagcgtt gcacctgttc
     1021 cgtaaggtgg tacaaagtct tcattggctt taaccacttg cttagctgca tcaataaatt
     1081 gctctgttga tacttgtggc atcaacaagc ggtctgctgt ggcttgtaaa cgcactgcat
     1141 tacggtctgg tctaaatagt tgaatagagc catctttggt gcgataagcc tttaaacctt
     1201 caaaagcttg ttgcccataa tgaagcgctg gagcgctttc tgagatatgt aaggtggcat
     1261 cttctgttaa ttgaccttta tcccattgac catttttgta ataagaaatg taacgaaatg
     1321 gcaacttatg atattcaaat cctaggttgt cccaatcaat tgctattgtc atcatcgtac
     1381 ctcttttctg cttttttcta ttgtaacttt ttttcaataa ttttcaagtt tattctactc
     1441 ttttgcatta atattctaaa tttaccataa aattaaaaag agttttcact ctttttaacg
     1501 tgttctagct accagtactt cttgatccga aatagtgtct gaaataaagg agccattgct
     1561 ggttctttcc gataacgaaa gcgtttctaa agcaatctcg taggtttgac cagtcttact
     1621 aatgacttta agcatttgtt gattagtttc ttcttcaggt atatcagtga acaaatcaaa
     1681 ctgctcagct gaagtatctg attgaacgcc tccggccaga aaaactctat gaggtttggt
     1741 ttttaactct cgtaggacca atagtccacg attggcacga cttgtctgag gaatatcatc
     1801 gacagccatc cgtttgagag aacccctctg agttaagaca aagaaagagt tacttgtcac
     1861 agcaaaggct gaggcaaggc tgtcatcatt tttcaagtta atgcctttaa caccagcaga
     1921 tttcaaccct tgaataggca cttcctgact ggagaatcgc aaagcataac catttttagt
     1981 cactaatagg aggtcttcca taataactgg tgacaaggta accacgcggt ctttgtcatc
     2041 ctttagcttc acatatttgg ttgatttaga tttataagtt cgccaaggac ttagttcttt
     2101 acgatcaaag cgtttgataa aaccattttg tgtgacagcc acatacaagc cctggtcaaa
     2161 ggaagtcaca atatcagcgt agagaatctc ttcttctgtc gcgaagtttg aaatggtttg
     2221 tgataaatgt tcaccgatat ccttccaacg taaatcggtc aattcatgga ttggtcggta
     2281 aatgacattg cctaaagttg taaacaacaa aaggtgttct gttgttttgg cctgtttaac
     2341 gaagatgagt tcgtcatcat ctctcttgcc aacttcttct aaactagacg cattgaagga
     2401 tcgtgggctg gttcttttga ggtatccgcc ccgtgtcaca ctaacaaaag tttcttcctc
     2461 tgcaatcaag ctggcagtgt caatctcaat gatttgactt tccgcttgta actctgataa
     2521 acgaggattg gcgaatttct ttttcacctc tcttaattca cgtttcatga cgttatacat
     2581 ggttgcttcg tcaccgataa tagcggaaag ggtcgtgatt aagtctctta aatcattttc
     2641 ttcattttgg agagtaacaa tatcggtatt agttaaacga taaagctgca aggttacaat
     2701 cgcttctgct tgttcctcag agaaatcata gctgactttc agattttctt tagcatcagc
     2761 cttattgtca gacgatctaa tcaaagcaat aatctcatct aagatggaca agacacgaat
     2821 caatccttca acaatgtgga ggcgtttttc agctttggct ttatcgaatt tagaccgctc
     2881 aataataata tctttacggt gactgatata gcttgatagt attttttgaa gtcctacttg
     2941 acgtggtgtg aagtggtcaa tagcaaccat gttaaaatta taattaactt gaaggtctgt
     3001 gtatttcaac aaataattta gaatggtttg gctatcagcc tcttttttca actcaatagc
     3061 tatgcgaaga cctgtgcgat cagattcatc gcgtacttct acgatgcctg ggactttatt
     3121 gttaacacgc acatcgtcaa tctttttgac caagactgct ttgttaactt cataaggaat
     3181 ctcagtgaca ataatttgtt gtttaccacc tttaagttcc tcgatttctg tcctagagcg
     3241 aacaacgaca cgtcccttac ctgtttcgta ggcttttttg atttcgtcag ctccttggat
     3301 aatgcctcct ggcgggaaat ctggtcctgg taaaaactcc attaatttct ctaaactagc
     3361 tttgggatga tcaatcatat acacaacagc atcaatcact tctgacaaat tgtgcggtgg
     3421 aatatctgtc gcatagcctg cggaaatacc agaagaccca ttgacaagta agttaggaaa
     3481 agctgctggt aaaacggtgg gttctttttc tgtgtcatca aagttccaag caaaagagac
     3541 cgtatttttc tcaatgtctt gaagaagata acccgcaatt tcagacaagc gagcttctgt
     3601 ataacgcata gccgcaggcg gatcaccatc cattgaacca ttatttccgt gcatttcaac
     3661 aaggatttca cggttcttcc aatcttgact catccgtacc atggcatcat aaatagagga
     3721 atccccatgt gggtggaaat tccccataat attaccaact gatttggctg atttacggta
     3781 acctttttca aaagtattgc catccttatt catcgaataa agaatccgac gctgaacggg
     3841 tttcaatcca tctcgaatat caggaagtgc ccgttcctga ataatatact tggaataacg
     3901 gccgaagcgt tctcccataa tatcctcaag ggacatgttt tgaatgtttg acatattcaa
     3961 atagctttct ttttcattat ttattaatta cctaaaaaac aatcgtcttt agcacttgta
     4021 attatctgtg agaaacttgt atgactaaaa caccgtattt tcttctaagg taaacttgac
     4081 gttatcctcg atccactgac ggcgtggggc tgctttgtca cccatcaaca cagaaacacg
     4141 tcgctctgct cttgccaagt cgtcaatagt aacacgaata agggttctgg tttcagggtc
     4201 catagtggtt tcccataatt ggttagcatt catttcaccc agtcctttat agcgttgaag
     4261 aatagccccc ttgccaaatt ctctgcgcag atcttccaat tcaccatcag tccaagcata
     4321 agcaattttt tcagttttgc ctttaccttt tgacattttg taaagcgggg gaagcgcaat
     4381 ataaacgtga cctgtttcta ctaatggtcg catataacgg taaaagaagg tcaataagag
     4441 ggtttgaatg tgggcaccat cggtatcggc atcggtcatg ataataatct tatcatagtt
     4501 gatatcctcg agattaaagt cagctcccac tccagctcca atggtataaa ccatagtgtt
     4561 aatttcttca tttttcaaga tgtcagccat tttagctttt tcggtattta aaactttgcc
     4621 acgtaatggt aaaatagcct gaaatttgcg gtctcgtcct tgtttggctg aacctcccgc
     4681 agaatctcct tcgaccagat acaattcatt tttcttggca tttttggact gggcaggagt
     4741 caatttcccg gatagtaggc ccttgtcttt tttgtttttc ttaccattgc gtgagtcatc
     4801 acgcgctttt cgagcagctt cgcgagcatc tctagcttta atggctttgc gaactagatg
     4861 agaagctact tctccatttt cgagtaaaaa gaaggttaat ttttcagaaa cgatactatc
     4921 gacaatcggt ctcgctaagg gacttcccaa tttgtctttg gtctgtcctt caaattgcaa
     4981 gtgctgctca ggaactaaga tagataatac tgctgagagc ccttctcgat aatctgagcc
     5041 ctctagattt ttatcctttt cttttaagag attggtttta cgagcatagt cattcatcgc
     5101 tttggtaata gctgacttca gtcccgtttc atggcttcca ccatctttgg tgcgcacatt
     5161 gtttacaaag gataagatat tgtcggagaa accatcgtta tactgcaaag caacctcgac
     5221 ttgaaagtcg tggtcttgac cttccatgta aataacaggt gtcaaggttt ccttatcttc
     5281 attgaggtat tcgacgaaat cttgaacccc attttcataa tgaaactctt caacaatcgg
     5341 ttcgtctcca cgaagatctg tcaagctcat cttaacgttt ttcaaaagaa aagcagattc
     5401 tttaagccgt tctgcaatgg tattgaactt aaagtcaatg gttgaaaaaa tcttatcatc
     5461 aggcataaag gtgacgacag ttcctgattt agacttagga gctgtaccaa cctttttaag
     5521 ggttgtaaca ggtttcccac cattttcaaa gcgctgacga tacactgccc cgtctcttgt
     5581 gatttcgact tctaaccagg cagacaaagc attgacaaca gaggagccaa caccgtgcaa
     5641 accacctgac gttttgtagc caccctgacc aaatttacca cctgcatgaa gaatcgtaaa
     5701 aataacttga acggtgggaa tccccatggc atgctgacct gttggcattc cacgtccgct
     5761 atctgccaca ctgaccgagc catctttatt gataacaacc ttaatatcat ctccaaaacc
     5821 agacaagacc tcatcgacag cattatcaac aatttcccaa atcaggtggt gcaatcccgt
     5881 agcatctgtt gaaccgatat acatccctgg acgcttgcga acagcatcta acccttctag
     5941 gacttggata gcatcgtcat tataattatt aattgtaatt tctttcttag tcaacaccga
     6001 cctccagaca gtttcatctt ttttatctta caagtttttt accaattttg caaaataatt
     6061 tgctaatttt ttccgaattc ttttccagat ctagttctcc aatctatgaa tatgttataa
     6121 taaggattat gaaattacta ctttttatta ccattgccta tttacttggt tctattccaa
     6181 ctggactatg gattggacag tacttttacc acatcaactt acgagagcat ggatcaggaa
     6241 atactggaac cacaaatact tttcggattt taggtgtcaa ggcaggaaca gctaccttag
     6301 ctattgatat gtttaaaggg acactttcaa tattgttacc aattattttt ggtatgactt
     6361 caatttcatc cattgctatc ggctttttcg cagttttagg gcatactttt cctatttttg
     6421 ccaactttaa aggtggtaag gccgtagcaa caagtgctgg tgtattgcta ggctttgctc
     6481 cgttatatct ctttttttta gcatctatct ttgttttagt tctctattta tttagtatga
     6541 tatctttagc tagtgtggtt tcagctatcg ttggtgtgtt atctgtttta acatttcctg
     6601 ccattcattt tcttttacca aattatgact actttttaac ttttattgtg atattacttg
     6661 cgttcattat tattataaga cacaaagata acattagtcg tatcaaacat catactgaaa
     6721 atctaatacc ttgggggcta aatttaagca aacaagtgcc taaaaaataa atttactaaa
     6781 agcctgactt tctctgaaag tcaagctttt ttgttttaac tcatttgtta attagggtaa
     6841 acaacctctc cgtctgcaat agtgtatttc acgacacctt tgagtttgtt accaataaat
     6901 ggggaattac tagctttaga agcaaaattc tcagtgatca gacgttcttg cttgtctgca
     6961 aaaataacca aatctgctgg accattttct gccaaataac ccgcatcaaa accataaagc
     7021 aaagctggat taagcgtcat tttttctaat agtgacataa gtgtaagatg acctggttca
     7081 accaaatgcg tcaaacctaa tgacaaagaa gtttcaagtc ctgtcatacc agatggggct
     7141 ttagtcatat catccacagc tttttcatcc ttgtgatgag gagcatgatc agtggcaatg
     7201 actgtgataa cacccgattt caagccttct atgacagcta agcgatctct ttgtgtacga
     7261 aggggaggat tcatcttggc gctggtacct gcgatcaata agagatcttc agttgttgaa
     7321 aaatgttgtg gggacacttc agcagttacc ttagcaccca actgctgagc aaaagccact
     7381 acttgaaccg attctgcttt agataaatgt tggatatgaa catgagcttg cctgtcataa
     7441 gcaatcatga catctcttgc aatcatacta tattctgcta caccagttgc cccacaaaaa
     7501 tgaaaatgct cctcagcaat accttcatta aaaccaagaa ccccatttaa ctgaggatct
     7561 tcctcatgca aagaaatgaa agtttggttg gcattagcca aatcaaaggc ttcttttaaa
     7621 actttagaac tttctaaggg aataccatca tctgaaaagc ttactgctcc tgcttccaac
     7681 aaagctttaa aatcagtcac gtcttttcca ttaaaggctt gggtgacact ggcattggtg
     7741 taaatatgaa tcttttcttt agctgcgcta gctagcactt cctgtaaagt ttcgacatct
     7801 gaaatgacag gattggtatt agccatcatg acaaccgtag tcacaccacc tgctgctgct
     7861 gccaaggctc ccgtgtgaat atcttctttg tgcgtttgac cgggttctct aaaatgcaca
     7921 tgaatatcga ccaaacccgg ggcaacaata agaccactag catcaatcac ttgagcttct
     7981 tggcattcaa tagctgaagc tatctttaca atctgtttac catcaatcaa gacatctgcc
     8041 acttgatctc tctgcgattt cgggtccata acgcgtccat ttttgatgag tatcatgttt
     8101 tctcctttat ttatctgttt taaccataag accttacgtt ctttaatagg aaaaatctac
     8161 tgcactcatt tcacttatta aaggtatcaa aatgtctagc ttaagctatt tagttgaaat
     8221 ggctggctta ttttagccaa tctacgccag tcatgccctc tttttctaaa atagcgttgg
     8281 ttcttgaaaa gggtttgctg ccaaaaaagc cacgataaga tgacaaaggg cttggatgag
     8341 agctctcgat gatgtggtgc tttggattag taatgaaggc ttttttcttc cttgcataag
     8401 ctccccacaa aatgaaaact acagggctgt ctttctcatt cagcacttta ataacagcgt
     8461 ctgtaaatgg ctcccatatt aagcctgcat gcccattagc ctgtcctgct ggcactgtta
     8521 aacaagcatt caaaagcaga accccttgac tagcccaagt gcttaaatca tgatggtcac
     8581 gaggaccaat gtcatctgct aattctttta aaatattaat aagggatggc ggagcagaaa
     8641 tctcttctgg aactgaaaat gataagccct gggcctgttt ggggccatga taagggtctt
     8701 gtcctaaaat caacactttg gtttcttcca aaggagtgac ttgtaaggct ttaaagacat
     8761 tttctcgtgg agggtagaca agaccggaag cataggcttc atctaaaaag tgattgatgc
     8821 gaccgtagta atgctccggc aaaaatgatt tgattttctc atgccaaatt gaatgagcca
     8881 taagattcct ttctaatcac gtcagtttct aagttaaata cgatgtcctt ttctatctag
     8941 tttaccacat tttaaataga aagaccctga aaatatgata tttccagggt taatattcgt
     9001 tttttacagg atattaaaca agtgctagct tattttctaa gaattcttgg taacgttcta
     9061 acaaaaaagc aataatccaa tagataaagg ctactaaaat gtacatggac atgtagtccc
     9121 actccctacc accgataatt ttggcatttt gaaaaatatc tggtacggta atcatggcag
     9181 ctagcgacga acttttaacc atatcaataa tgacattgcc tagaggagga actgcaattc
     9241 taaaggcttg aggaagaata attttcttaa ccataagagc atatggcaac cctaaagcct
     9301 tagctgcttc ccactgtccc ttgtcaatag cttctataga agagcgaaaa acttcagaaa
     9361 tataggcagc gctaaccata gaaaaaccaa gataagcgca aagtaaagct ggcaattcta
     9421 aaccataata aggcaacccg aaataaagaa caaagagcac cacgatcatc ggcacacctc
     9481 gcataataga gatgtaggcc ctaacaagat agtgtagcag tggctgatgt gaccttccca
     9541 gaagggctag gcctaaacct aaaaacagac ccgtaaaaaa actgagcaac gaaataccaa
     9601 gggtataagg taatcccgat aacacaaatc ctaaactatc tttcattaat gggatattaa
     9661 tcatgtggtt aggactcctt taacatcaag tattagttaa cgtctttcgt atcaatgacg
     9721 ggaatttttt tgtctttgcc aaaaggtttt gtcaaatctt gaccagcata gtaggtttca
     9781 gagattttct tcaagctacc atcttttatc atgtctttaa taacagcatc tatttttttc
     9841 ttgaggctat cgtctttttt gttcataaca attccttgtt cggttgggtt gtactgaaca
     9901 tcgctcattt tgacatttag atttggattt tgagataaca tgtaatccac aaataatttt
     9961 tgagctgggt aatcatttgg aatgaaatct gttcgaccgt tagccacatc gtttagataa
    10021 acatctcctg taacattatc gtaggtcacc agttcagctc cctgtttttg cgctactttc
    10081 atgtattctg ttccagaagc accagctgct ttttttcctt tccagtcgct aagatctttt
    10141 ttaaccatgt ttgagctgcc atcagcacgg acaatcatgc ctcctacccc gtatttataa
    10201 ggcgtagaga tattgtattt tttctgacgt tttggggtaa tgtcaaagtt gttcaaagaa
    10261 atatccactc gaccactatc aactgaggta aacgcttggt caaatcctgt ttcaacaaac
    10321 ttgactttaa tgttaagtcg tttaccgatt tctttgacca tatctacttc gtaacctact
    10381 aactcattat tatcgttgta aaaagaagtt ggctgatagg ttcctggggt agctactttt
    10441 aacacccctt tttctttgat agtgtcccaa cttgattttt gagatttatg tggcgcacat
    10501 gctgccaata aaaggctggc aagtccgata gacagtaaag taactgattt cttcatagta
    10561 actcctttat taagataaga atagtataac attttgatta agttgtgtta tcagtgagcg
    10621 ctcaatctct ttaaaaagtt aatctataat agttaaactg ttttataaga ttattattga
    10681 ggaatcttca ataatcctgc tgcctcaaac tgctctgcaa ttcctaataa taggtcctct
    10741 ctacctttgg ctgcaattag ttgaatgccc attgggagcc cttccttagt ttcgtaagta
    10801 ggtaaactaa tagctggctg gccagttaga ttaggcagag ctgtgtaagg attaatagcc
    10861 agactcttac caaacatggt ttcgaccaaa ttgaattgct cttcactgct gaaaatttca
    10921 gcttgagcca agttagccat gagtttcgaa tctgggacaa gttctccgtg cttaggagct
    10981 ggtgtgttgg ttgtgaacgt caacaacagg tcataagtct catgaaaact agccatggtt
    11041 gcactgtacg tatcccattt ttgaaggacc tgtgagtaac gccaagctgg gatgtcttta
    11101 cctgattggt aaatagccca ggtcatggtt tccatatcgt ctttggtcat cggacgtcca
    11161 aaagtgtctt caatatcagc aaacatagca gccgtttcca cactattcat aatataataa
    11221 tgacgaatca cttctgtcat atttacagga aactcttcca attcaactag ctgatgccct
    11281 tgttctctta gccaagttac tgcttgtctt aaagcttttg cagtatctaa agatactggg
    11341 ctaccgtcac ttaaccgttg ataaaaacca attgtcaagg aacgttgtag cgattgataa
    11401 atactatctt ttgttaaggt ggctaggggg aaggggcttt ccatttgttc catctgtaaa
    11461 tagtagagta gatttctagt atctctaacg gatttggtca aggcaaaatg aactgaggct
    11521 ccttgccagc ttcgataaga accaggtccg acaggcatgc gcccacggct aggtttgagc
    11581 ccaattaagc cattaaacga ggctggaatt cgaatagaac caccaccatc actagcagtt
    11641 gctagtgcac taattcctga tgacactaga gcagcagctc ccccagatga gccaccagca
    11701 tttcgtgtat tatcctttgg taaattcact ggtccgtgca aactgctatc gctaatattt
    11761 ttaaagccaa attcaggcgt gttggaacgc cctaaaataa taaagcctaa agcttctaat
    11821 cttttcacaa ataaatccgt tttagtcgct tgatactctt taaacaatct ggaacctgag
    11881 gttgatgagt gaccttttaa ttcttgtccc aaatctttca aaaaaatggg aactcctgca
    11941 aaaggcttac ctgaaaaatc cctttgtttg gcttcttcta gggctgcttc aaagcgttct
    12001 gaggtaatag catttaaggt agggttcaac tttttagcct tataaatagc ctgggttact
    12061 aattctagtg gtgtggtctg accggtctga acagcaatag ccatagccgt cgcatcttga
    12121 taagtcatag ctactcttcc tttctaagat atgaatccta aaacattctt ttttattaaa
    12181 acacaaataa aagaaaacca ccattaaaag gttagaaatt agaatgtgat gtgtaaggaa
    12241 tgtagacaaa acaatcaaaa cataacattt tgaattgggg ttaaagagat tttttcatta
    12301 aaaataaacc tggctgatag ttccttattg ttgccagttt acctggtctt ctttaaattt
    12361 tttaagtaaa tgtaaaccat cattagtaat atagccttgc aactttgcaa ctgcaattag
    12421 ctcagtataa ttagaaagcg taatcaactt gataccagct tctttaaaat tctgactagc
    12481 ttttggtaac tcataagtga aaatcgcaac aactcccaga acgtcagctc cctcacgact
    12541 ggctgctgcg gctgcatcta gtaccgaacc acctgttgaa atcaaatctt caatgataac
    12601 cattttttgg cctttaagca cacgcccctc aatctggttg cctgctccat gatcttttgg
    12661 cttactgcga atataagcaa aaggaagagt cattttatct gctataatgg caccgtgagg
    12721 aatacctgct gtagctgtac cagcgatgac ctcaacttct gggaaatgag ccctgatagt
    12781 ttccacaaac ccattctcaa ttaaatcacg agtcttagga taagaaaggg tgacacgatt
    12841 atcagtgtaa ataggtgatt taatgccaga tgcccacgta aaaggatctt caggctttaa
    12901 ataaacagct ttaatatcaa gtaattgagt tgcaatttgg cttgctagtg tcatttctta
    12961 ttctcctttt tcttctttaa cagacaagtg ttggtttcct aatcttatct gttagcctgc
    13021 ccactcagct tttatggctt ggtaagcagc cactgggtct tttgcctggg taattggtcg
    13081 ccctaccaca atataatcac ttccaatgcg tcttgcttgg tttggagtca tcactcgttt
    13141 ttgatcgcca atattactgc ctttaggacg aatgccagga gttaagcaag taaatcccgt
    13201 aggcgtcacc gccttgatag cttctacttc ttgtgccgaa caaaccaccc catctagctg
    13261 agctttagct gcccccttgc tgtaatgcaa aacagactct aaaagactcg tttgaatatt
    13321 ttgatcacca cgcatttggt cttcactggt tgaagttagc tgcgttaccg caattaaggt
    13381 agggccttgg cctagtcctt ctcgagctgc ttttagcatc tctacaccac cagctgcatg
    13441 aacagttgcc atatcaatat ctaattcttt aagaactgcc atagcagcac gaacagtatt
    13501 tggaatatca tgtaatttta aatccaaaaa tacattatgc cctaacgatt tgatagaccg
    13561 aacaatatct ggtccttgcg cataatataa ttccatacca attttcacgt atagtttttc
    13621 ttctgctgga aataagtcta aaaatgcttt agtctcctca aatgatgaaa agtctaaagc
    13681 aataattggg cgttcttctt tcataactta tcctttctat aatgtgtcaa tatctcatta
    13741 agtaccaaaa agcctcgcta ccaaagaagc gaggctacag caaactaaaa gggaattccc
    13801 tttttttatc ttgtatacct tgtttgcctc tctggactca cttaaaggtg tctaaattta
    13861 aactattata gcttttttaa aacaagatgt caaaactttt tgttatttga acacattttt
    13921 cctactatat ctttttttgt acacttacgt caactcattt tatcattttt acccaatcat
    13981 ttattcaaac tcacctgtgg gtaccttagg gccttggtaa tattttataa aagcttcttc
    14041 ttcaagatta accctctgga tatgttcata gagcaaatcc ggaataggag cttccttaag
    14101 tgacaaagca ctcactttta aagatgaaaa aacatcactt aagaccccaa aaactcgaat
    14161 gcgtttatct ccaataataa tttgaaagac ttctttggac tggcataaat ctatcagatg
    14221 atccactcct ttaatccaat tatcgacaat atccaaagtt ttgttcatca acttaaaagc
    14281 tgattcttca taccaaaagg tagactcaat caagcgttgc tgcatatcca aggtatcaat
    14341 ggccgcaaca atatctccca actcagactg tactaaatga gctggaaatt cccctccaag
    14401 tatagaagga gttcgttcta caagcttcag ttcatctcga aaaagagtca aatagtggat
    14461 actgaccaat aatttttgga ttaagatttg atgactattt tgttcagtaa cattcacacg
    14521 accaccaccc tttgattaga aaaataccta tttgttaata ctattaatat aacacaagaa
    14581 aaataaaagg gcaatgaaat tgatagattc aactctcaaa attgaatcat atttatccta
    14641 ggccatattg agaaaagact ccagcgcttt ttcaaagttc taaacccatg atgacgtttg
    14701 tgcttgcgtc tttatttttt ttgagctaga ctgtacttat gagaattcaa caactgcatt
    14761 atattatcaa aattgttgag tgcggctcta tgaatgaagc tgctaagcaa ttatttatca
    14821 cacaaccaag tctatccaat gcggtcaagg atttggaaat ggagatgggc attaccattt
    14881 tcaaccgaaa tcctaaaggg atcaccttga caaaagatgg ggtggaattt ttatcttatg
    14941 ctcgccaaat tatagagcaa acatcactgt tagaagaccg ctataaaaac cacaatactg
    15001 gccgagagct ctttagcgtt tcatctcaac attatgcctt cgtagtcaat gcatttgtct
    15061 cactcctcaa gcggaccgac atgactcggt acgaactctt tttgcgcgag acaagaactt
    15121 gggaaatcat tgatgatgtc aaaaactttc gatctgaaat tggtgttctc tttatcaacg
    15181 actataaccg agatgtcttg accaaattat ttgatgacaa tcatttgact gcctctccat
    15241 tatttaaggc acagcctcat atttttgtca gcaaatcaaa tcctctagca actaaaagcc
    15301 tattaagcat ggacgacttg agagattttc cttacctgag ctatgaccaa gggattcaca
    15361 actcctttta tttttcagaa gagatgatgt cccagatgcc ccacaacaaa tcaattgtgg
    15421 tcagtgaccg tgccaccctc tttaacttaa tgattggttt agatggctac accgttgcca
    15481 gtggtattct aaatagcaat ctaaatggtg accagattgt ggctatcccg ctagatgtcc
    15541 ctgacgaaat tgacattgtt tttatcaagc atgaaaaagc caacttgtcc aaaatggggg
    15601 aacgttttat cgaatacctt ctcgaagaag taacctttga ttaatgtctt tttcaatcgt
    15661 catactaaaa aaacacggta gtaagacctg tatcggtcaa gttatcgtgt tttttgataa
    15721 atatcagaca atagattgtc tccaaaggct caactccttt ttaataatgg cattcatgtc
    15781 atcaaagtaa aaaggctcac gtcggtagat tacaccagaa aaagtcgcta aggtgataat
    15841 gttttccaaa aaagcctgag aagaaaaatg agtggtgcga tgcagttcct cttcatcaaa
    15901 aggcttaatc aaatgagcca gaggattacg gacagccttt tcaaaatgtc gtaacaaaaa
    15961 aaccaagtcc ttgatttcct gaggtaagga ggtcaacgtc aacatgtctg ctaagctttt
    16021 ggtcgtcaca ttgcgagact gcttttgaga caggtaagcc ttgaaaacct cgtgatcaga
    16081 ttccaacatg gcctgaaact gccaggtatc atattggtca ttctttgtat caaaaatata
    16141 agccttgaag tttggaattt ctgacgtgat tagtctgaga aaaagtcggt aaagaatagg
    16201 cgacactgac ctgacgaaat caataatagc accgtttttt actttaactt ctaaatccaa
    16261 aatgtaattg gcaatctgct catcttcaag cgattggtta atccataatg aacagtggta
    16321 ctggtcttca atggtccgat tctctgctgc atgttccgcc agaaaggcaa ggttcaattc
    16381 tctgcgctct tttaacatct ctagtaaata gagagcagtt ttagggatat ttggcaaggc
    16441 tttagcaatt ctaaaggcgt gattataagc atagacatcc aaaaggatgt ctagcgtttg
    16501 attattagtc attggcaatt aaggtttcca agccgacctt catcatatca gtgaaagttg
    16561 tttggcgctc ttcagcagtg gtgtcttctg ttgggtcgtt caaattgtca gaaattgtca
    16621 taataccaag agctttgaca tggtgctgag cagctaaata gtaaagagct gctgcttcca
    16681 tttcgatggc tttaacaccc aatttaccaa gagccatatt acgctcaggc atgttagtgt
    16741 aaaagacatc agaagaaagc acattcccaa cgtgagttgt tactcccatt tctctggcga
    16801 tatggtaagc cttgtcaagt aaaccaaaat cagcaatttg tgggaaatca aattctggga
    16861 agtcattacg gataatgttt gagttggttg ctgctgcttg ggcaagcacc aattcacgca
    16921 catgaacttc tgggtcaatc gcacccgcag taccaacacg gatcaatgtt ttgacaccgt
    16981 aatcaacgat taattcacga gcatagatag agatcgaagg catccccata ccagttccca
    17041 tgacagaaac gcggtgccct ttgtaagttc ctgtgtagcc aaacatgtta cgcacttcgt
    17101 taaaacacac tgcatcttct aggaaatttt cagcgataaa tttcgcgcgc aaagggtctc
    17161 caggtagaag aattttatca gcaatatcgc cttttttggc agaaatatgg atagacataa
    17221 attatgatac tgagggcgtt aaaagaacga tggcaaaata ggaagttggc agaaaatcct
    17281 gattttctag acaacttatc tttttgacca agtccttagc ccgaattcaa attaatgaac
    17341 tcagccctca cctttcttat ttttttattt tttataagta agaaaaacag ttctccgccc
    17401 gtattcaatt caatgaatac agttagccct acctttcctt ttattttgta gaaggtcaga
    17461 gggcggacag aaagcaactg aaatttaggg aactaacgcc atgtgtgagc acaaaagtta
    17521 gtttatctag tttccgagct ttccgcccgt attcaattga atacaacccc attcctttca
    17581 taattgatat tgaatagaag aagagagcta aaaatcgagt tcaaataaga aaggactaac
    17641 tctctttcct ttattattta aaaattaata cgaagaaatg ttcgagtcca tgcttaattt
    17701 aaaccgaata cgtctctttc ccttcgttgg ttatgttagt tagaaaagct agaatctgag
    17761 ttcaacattc atggaactca cactccgtga ttattttttg atttttttat tgcgaacaga
    17821 tgtgccaaac tgacgacata aaataacatt cctgtaataa tgctccagtt gattttgttc
    17881 gtcctacaac tccgctaaaa tagctttaac aagacctttg aaatcttctt tgatatgttg
    17941 ggtcacttcc acaacttctt catggttcaa ttctgattga aaaccagctg caaagtttgt
    18001 aatagctgaa atgccaagca ctttaagtcc agaatgagca gccacaataa cttctggtac
    18061 agttgacatg ccaacagcat ctgctcctaa tactttgaaa gcacggattt ctgctggtgt
    18121 ttcataagtt ggaccagtca agcccatata aacaccatct tctagtttga tgttcatttt
    18181 ttcagccact tcatgtgcct tatcgcgata aaccttagta taggtatcag acatatcagg
    18241 gaagcgtgga ccaaactcgt ccaagttttc accaattagt gggttatttc cggtcatatt
    18301 gatatggtct gtgattgcca tcaaggtacc tgggccgtag ccgataccac cagctgcatt
    18361 tgtgacaaga acgccttcac atccaagagc tttcatgaca cgaacaggga aagtcaccac
    18421 ttcaagcgga tttccttcgt aaaaatggaa acgtccttgt aaggcgagca ctttacggcc
    18481 agctaaatct ccgtaaacta actttccagc atggccaaca accgttgact tgccccagtt
    18541 tggaatatct gcataatcaa taacaatagc attttctact tcttcagcaa gttcaccaag
    18601 gcctgaaccc agaattaatc caaattcggg agtttcaatt cctttagtaa ctaaaaagtc
    18661 ttttgtttcg ttaattttag tcatcaatga catctttttc tccttttacc tcaatagggt
    18721 tcacactctc gccatcctct ttcatataag gactaggcag gggaacagga agaatatcca
    18781 gtaaggtctc agaaggacgg caaagtttta ctcctttgcg agtcacaaca ataggacgat
    18841 tgatcaaaat tggatccgcc aacatggcat taataacgtc tttctcagct actgcttgat
    18901 ttgctaatcc atgagcctca aattcaggaa cattggttcg caagagttct cgcgcagaga
    18961 ttcccatcga ttgtaagagc tcaattaaag tctcccgatt aggtggcgtc tgcaaatact
    19021 caataatagt aggctcaata cctgcatggc gaatcatggc aagaacatta cgtgaagtgc
    19081 cacagtttgg attatgataa atcgtgattt cttccattat caattactaa ctttcttatt
    19141 ttaagtgacc aaggaatgac tccccaatca tggctgtatc aactccaaaa ttttctgcaa
    19201 cagttgctga aatatccgca aaatgccctt gtggaataag accatttcca gtaaaggatg
    19261 cagagtaggc aagcaatgga atgtattcac gagtgtggtc ggtgcctgca taggttgggt
    19321 cattaccatg gtcagcagtg atgagaagca aatcgtcttc tttcatattt gcgaagattt
    19381 caggtaggcg attgtcaaat tcatgcaagc agtcacgata accctctggg tcacgacgat
    19441 gaccaaagtt ggcatcaaaa tcaacgaggt tagtaaagga gaatccctta gtaaactcag
    19501 gtaattgaag agtcttaata agcgtgtcaa taccatggct gttcgactta ttgtgtccca
    19561 tgtcgtttgt aatacctgaa ccattaaaga tgtcattaat cttaccaacg gcataagttg
    19621 gaacgcctgc gtcagccagt ttgttcaaaa cggtatcttg gaaaggagac actgcatagt
    19681 catgacggtt agccgtacgt gtaaagtttc ctggttcgcc tacataagga cgcgcaataa
    19741 tacggcctaa aagggcaggg cgttcaagcg tgatggagcg agcatattca caaatcttgt
    19801 aaagctcttc cacaggaata atgtcttcat gggctgcaat ttgaagcact gggtctgctg
    19861 aggtgtaaac aatcaactca cctgtttcca tttgacgcgg accaaaatca tcaataaccg
    19921 cagttcctga atagggttta ttagcttcac gaataatttt gcgacctgag aattcttcaa
    19981 tcttagttaa aatctcttct gggaaaccat tccagaaagt gtcaaaaggt tccgtaatgt
    20041 tcaagcccat aatttcccaa tggcctgtca tggtatcttt tccaagagat acttcttcca
    20101 atttggtcac gtaaccagta ggattgtctt ctgttggaat agtttttagt ggtatcggac
    20161 gagaaatgtt tccaagtcca atttttgcca tatttggaac cgataagcct gctgtttctg
    20221 aaatatgacc gagggtgtca gaatctgtat cagctacacc agcattaaag aatttgtcag
    20281 catctggcgc tgcaccaata ccgacagagt ctaaaacaac caagtgaata cgattaaatt
    20341 ttgacataag tctccaatct aggggaggtt acggttgact ccccaatacc tataaaatat
    20401 attaacactg ttatatgcta agactagcct gctttaggcg cttctaaaac agtaacgccg
    20461 tctttactag caacaatcac cttatcaacc ataccattaa agagaccgtg ttccacaaca
    20521 ccaactgttc catctagcag gtgaccaaaa gcaacaggat ctttaataca acccaaatca
    20581 agatcaataa tatagttttg catgtctgtc accaaacgac tatcaccttt catacgaaaa
    20641 gacggtttgt aaccagcttt ttcaaagaca cggaacaaac gatcagcacc atattgaacg
    20701 acttcgactg gtaacttaaa ggcacccaga tgctctacca ttttagaagc atcaacaacc
    20761 cagatgtatt cttttgttgg tgttgcaaca attttttcca ttagtaaggc tgcgccgcca
    20821 cccttgattc cattgaaatc cttatccact tcatcagcac catctacggt gaggtcaatg
    20881 ctatcaatat catctatcga ttttaaagga atgcctaagc cttctgcttg cttgctagtc
    20941 acacttgacg tagtcacacc aaccacttgc agtccttctt gctttacgcg acggccaatt
    21001 tcctcaacaa aatagtaagc cgttgaccca gttccaagcc caatggtcat gccatcagtc
    21061 acatattgcg cagcggtaac accggcaatt tttttgagtg cttccatgat tcccccttat
    21121 aatagaattg cgtcttagca ctttattata ccatgaaagc gccaacttgt taatgaaaac
    21181 atttgttttt ctctcattga cagcctaagt gctatagaat aggatgatct ttttaaaact
    21241 tatgatttat tctaaagtca tcatataagc acttactttt cgtgtttatt tagctttttg
    21301 aaaatcaagt gtttttgttt gacctttact gaccttttga ttataataat actataagat
    21361 gagtaaaaat aatgtctgaa tcattttatt agcaaagggt ttcctatcat gtgaaatcct
    21421 aacaacgatt ctgcgactgc ttacaaacat cttatagtct attttttatt gcgaggtaac
    21481 tgatatgaca catttttctg gtaaagatcc ttttgtaaat atggatgata ttttcaacca
    21541 attaatggca aacatgggtg gttatcgtag cgaaaatccc cgctatctcg ttaacggtcg
    21601 cgaaataact cccgaagaat tccaacacta tcgtcaaaca ggacaactcc ctgtagcgac
    21661 aaccaaagca acaaattctc aaatgttaac acctaaagct gatagtgtat tgactcaact
    21721 cggaactaac ttaacacaag aagctcgtca agggcatctt gaccccgtca tcggtcgtaa
    21781 caaagaaatt caagataccg ctgaaatctt ggcacgacga actaaaaata atcctgtcct
    21841 tgtcggagat gctggtgtcg gtaaaactgc agtcattgaa ggtttagctc aagccattgt
    21901 taatggagat gtcccagctg ctattaaaaa caaggaaatc gtatcaattg atatttctag
    21961 tcttgaagct ggtacacagt atcgtggttc ctttgaagag accattcaaa acttgattca
    22021 agaagtaaaa gaagctggga atatcatctt attttttgat gaaattcatc aaatagttgg
    22081 cgctggtgcc acaagcagcg attcaggctc aaagggactt gcagatattc ttaaaccagc
    22141 cttgtcacga ggagaattaa cactgattgg tgctactact caagacgaat accgcaatac
    22201 tattttaaaa aatgctgctc tcgctcgtcg ctttaatgaa gttaaagtga atgcaccatc
    22261 agctgaagat acttttcaca ttttaatggg tattcgtaat ctttatgaac aacaccacca
    22321 tattaccctt cctgataatg ttctaaaagc tgctgttgat tattctattc aatacatccc
    22381 acagcgtagc ctgccagata aagcaattga cttactggat atgacagctg ctcatttagc
    22441 tgcgcaacac ccggtcactg acttaaaaac actcgaaact gaaatagcta aacaaaaaga
    22501 gaggcaagaa aaagctgtcg ccaaagaaga ctttgaaaaa gctttagcag caaaaacacg
    22561 gattgaaaca ttacaaaagc aaattgagca acataaccaa acccaaaatg tcactgctac
    22621 agtcaatgat atcgcagagt ctgtagagcg cttaactggt attcctgtct ctaacatggg
    22681 gactaatgat ttagaaaggc tcaaaggaat tagcagccgc ttaaaaagcc atgtcatcgg
    22741 acaagatgag gctgttgcag cagtagcacg cgctattcga cgaaatcgag caggttttga
    22801 tgatggtaac cgtccaatag gttctttcct ttttgtgggt ccaactggtg ttggtaaaac
    22861 agagttagct aaacaattag cacttgattt atttggttcc aaagatgcta ttattcgact
    22921 tgatatgtcc gaatataacg atcgcactgc tgtgtcaaaa ttgattggga caacggctgg
    22981 ttatgttggc tacgatgata ataataatac cctaactgag cgtgttcgtc gtaaccctta
    23041 tgctattgtc ttactagatg aaattgaaaa agctgatcct caaatcatta cacttcttct
    23101 acaagtgtta gatgatggac gattgacaga tggacaagga aatactatta actttaaaaa
    23161 taccgttatt attgctacat caaatgccgg ttttggccaa caagatacgg aaacttctgg
    23221 gtttaacatt atggatcgca ttgcacctta tttcagacca gagtttttga accgttttaa
    23281 tagtatcatt aaatttaatc atctgcaaaa agaaaattta gaagaaattg ttgatttaat
    23341 gctagctgaa gtaaatcaaa ccaccgcaaa aaaaggtatt agtttaacga ttgctgatga
    23401 cgctaaagct catttgatag atttagggta caatcgcgct atgggagctc gtccattacg
    23461 acgtattatc gaacaggaaa ttcgtgaccg tataactgat tattatcttg accatccaga
    23521 agtcaaaaaa cttcaggcaa tcctaaaaga aggacaacta gtgattaggc aaaacgatca
    23581 gtaataaact tcttcaactg aataattttc aaaacatgaa aaaatccgtc ttgtgactac
    23641 gttatacact tgacggactt ttttttagcg cttttttaaa aataattttt tcatcgccta
    23701 ataactcaag tttctttcca aatctggtgt aatcaaaata accattaggt gtgagcaatc
    23761 cttttgaaaa agaagtatgt cccgctgcta cttcttcttt gatatcaatg gtgtgcaaaa
    23821 tacgattaac ttttcctttg agaacaacag cagataaatg tcctgttttt tgattatatt
    23881 tgcctccgat ctgagaagct aatttctcaa aagcttgatc taaaatcatt tctaattcat
    23941 ggctagctgg catactattc tcaataattt ggcgttcttt actactcaag tcaccaacaa
    24001 ctaaatgatt ttcctttaat gtctttaata attcattttg gtgataagca gctaaacgtt
    24061 tgacaaaaat gtctcgttca acttgaacac taaaactcaa gtcaacgttg ttatttttaa
    24121 ctgttagtat catctgagat gacgttaata aactatcatc aataagaggg ctctgatgca
    24181 aaccagtaag acgtttagca aaatcatcgc ctaacttctg atcaatgctt gttgttcgcc
    24241 agataccttc aatagagcta ttacgatatc gaacaccaaa aagtacagca agcaagataa
    24301 gaaaaataat aaatacaaaa agggcattgc attgatggca taacaatgac tttcctttag
    24361 agcgcccttg ggctacttgt gtcatgactc atctccttaa tataaaatac tagcatgtca
    24421 tcattaaggc gtcaagtaaa atcggtaaac ctaactatga ttttttatgt tttcgataag
    24481 aaaaacaccc tctactgaga atgttttagc atagataaat caacacctat cgctagacct
    24541 gctctaaaat agcatcccaa gaatcatcga taccaatacg ttctaccgaa gaaaatacta
    24601 taaaagtatc agatttgtca aaattcaaag ctttcttgac cacagactca tgtttgttcc
    24661 atttgccacg aggaatctta tctgctttgg ttgccacaac aataacagga atgtcatagt
    24721 acttcaaaaa gtcatacatc tgaatatctt cttttgaagg ggcatgacgt aaatcaacca
    24781 aactcacgac tgcacgcaga ttgtctctgc tggttaagta ttcttcgatc atctttcccc
    24841 atttggcccg ttcactttta gaaaccttgg catagccata accagggaca tccacaaatc
    24901 taagcttgtt atcaatattg aaaaaattta atagttgggt ttttcctggc ttgcttgagg
    24961 ttcttgccaa atttttgcgc cccaatatgg tattaataaa acttgattta ccaacatttg
    25021 aacgtccagc aagggcaatt tctggcaaat catcttgggg gtaatgagat ttattggcag
    25081 cgctcaataa aattgaggcg ttatgggtat ttaagacttg ttcttcagcc attatttctc
    25141 cttaagctgt ctctaaaacg ggttttgact tgccttcgac agcagccttg gtgatacgca
    25201 cttttgtgac atcttcttgg cttggaattt caaacataat gtctaacatc gtttcttcaa
    25261 taatagaacg aagaccacgt gctcctgttt tacgttcaat ggctttattg gcaatggctt
    25321 ctaaggcttc cttatcaaat gccaattcga cgccatcgta agaaagaagg gcctgatatt
    25381 gcttgaccag ggcatttctt ggttctgtca aaatttgaat caaatctgat gtgtttagtt
    25441 gttcaagggc tgccacaact ggtaagcggc caataaattc tggaataagc ccaaactttt
    25501 gaatatcttc tgaaataatt tcttgcatat aagaagcatt gtcatcaatt ttacggctgt
    25561 tttgaccaaa accaataact ttttcaccta aacgttgttt aacaatctcc tcgatgccat
    25621 caaaagcccc gccaacaata aacaagatat tttttgtatc aatttggatc atttcttgat
    25681 tagggtgctt ccgcccacct tgtgggggaa cacttgctac cgtaccttca ataattttaa
    25741 gaagggcttg ctgtacacct tcaccagata catcacgtgt gatagatacg ttctcacctt
    25801 ttttagcaat cttatctatt tcatcaacat aaataatacc acgctctgct cgttcgacat
    25861 tatagtcagc agcctgaatc agtttgagta aaatattttc cacatcttct ccaacatacc
    25921 ctgcttcagt caaagaagtt gcatctgcaa tagcaaatgg tacattgagg cttttagcca
    25981 gagtttgtgc taagaaggtt tttcctgaac ctgttggtcc aatcatcaaa atgttggact
    26041 tttgtaaatc cacatcatcg tcatcacgac tttctgtaaa cgagacacgc ttataatgat
    26101 tgtacacagc aactgataaa gcacgtttag cacgatcttg accaaccaca tattgattta
    26161 aaacatcaag gagctctttt ggttttggaa cttctgtcaa atcggcaagg acttcttcag
    26221 ccaattcttc ttttataatt tcttgtgata aagctacgca ttcattgcag atgaaaacat
    26281 tatttcctgc gataattttt ttaacgtcat cctggctttt accacaaaat gaacagtata
    26341 ctttaatatc gttagttcta cttcctgcca tttcttataa ttctcttact ttctcttatc
    26401 ttttactgaa ttttaatatt agtcaatgtg ttgtattggt ttttggtgat tcttgcttga
    26461 tagctaaatc ttcaccagtg ctgtctttgc aagtcgcatc tcaaaacaat gtaccataga
    26521 aggcgtgaat actattaacc agattagtaa acgcatttaa taagaacaga cttgctaagc
    26581 cataacgatt ctttttaaaa gctgggatgg cacaaagaac acaaatcacg cacaaaaaag
    26641 ccgtaaatac tccaaaaata ctacgttgca tcgcttatca tctcctcaga ctatttgtgt
    26701 tttaaagcag taacggtaaa atcataagga tttttagcgt ctcgagcata gaacgtttgg
    26761 ctttcttgcg tgaaatgact aaaatctaga tttggtcggt aggtatctcc tttaaaacga
    26821 tgatggataa ctgtttttat gatacgatcg aaataaccat taaacgcttc taaaacctta
    26881 ttcccaccaa tgatataaag tgttttatcc tgcgcatggt accactccaa gactttttca
    26941 atactagtca ttgtcaacac ctcatctact tgataatctc tatttcttgt catgacaagg
    27001 gtttgacgtt gaggaagtct tttgcaattc attccttcaa aagtcacacg gcccattaag
    27061 attgcttgat gtagcgttgt ctttttaaaa tgttctaact cttttggtaa ataccatggt
    27121 aacttacccg caacaccaat aagccctgct tcatcctctg cccaaatagc aataatttcc
    27181 tttgtcatta attatttcct tcattttaaa ctctatttat tttaccaaat ttatgaacaa
    27241 aatgctcaca aaaaatctaa ataaagttta aatagcaagg tcaaagtgca actgaggctt
    27301 cactggatca taattttgta attcaaaatc atctggttta atatcaaaga aattagtccc
    27361 atctggaaca tttaaaacaa gcttaggctg actggcaact ggctgtcgtt ttagtaattc
    27421 ttgagcctga tcaaattggt tgtcataaat atgtaaattg ttaacaaaat aaaagaactt
    27481 acctattttc catccaaaat gtttagcaat catcatctgc aaggcaacgt attgcatggc
    27541 attgatgtga tgagcaacta atatgtcatt agaacgttgc gtcaaactag catctaaata
    27601 aagatcttcc cctacacgtc taacatcaaa catgatttga aaggcacatg gcaacaaccc
    27661 ttttgtctcc tcaaatgctt catagtccca gagagaaatg acattacgac gattccaagg
    27721 attttctgct aattgcttta gtatttttga gatgatatca tgttttttga ctacagcacc
    27781 ataacgttgt ccaatagtac gtgtctggtc aacttcccat tcattccaat aatgaacatt
    27841 atatttagct tctagcacat ctaaactgtt agactgatct tgatatatcc aaaataattc
    27901 ctttatagca gatttaattg gaatgggtcg taaagttgtg atgggaaact ctcctttagc
    27961 taaatcatat tcagcaaacg ccccagtaat atacttagaa tgagctgttc gaccatcttt
    28021 atatttagga cgtgcttgct cactcaatga tccttcgttt ataatttttt gaatattagc
    28081 tttaaaaatc tggtcagctt ttgtcatctc taataacctt tctgtaagca tacttcatac
    28141 tattctaact aattttacca aaaaatacca gaataaataa acattcgaaa aacttcatgt
    28201 ggtcatgaac attttaacta ttaaaggata aaacaaataa ctttatcagt ctaattttgc
    28261 agtaaaatgt gatagaatgg gtaagactat aaaaataact aaaagaagga caaatatgac
    28321 aattggaatt gataagattg gttttgcaac cagtcaatat gtcttgaaat tggaagattt
    28381 agcgcttgca cgccaagtgg atccagcaaa atttagtcaa gggctactca ttgagtcttt
    28441 tagtgtggca ccagtcactg aagacattat tactttagct gcttctgcag cagatcaaat
    28501 cttaaccgac gaagatcgag ctaagattga tatggttatt ttggcaactg aatcgagtac
    28561 tgatcagtca aaggcatcag ctatctatgt acatcactta gttggtatcc agccttttgc
    28621 acgttccttt gaagtaaaac aagcctgcta tagcgcaact gctgctctag actatgctaa
    28681 actgcatgtg gcttctaagc cagattctcg tgtccttgtt attgctagtg atattgctag
    28741 atacggtgta ggatctcctg gggaatcgac tcaaggctct ggtagtattg ctcttttggt
    28801 aactgctaac cctcgtattc ttgctctaaa taaagataat gtggctcaaa ctagggatat
    28861 tatggacttt tggaggccta actatagttt cacaccttat gttgatggta tttactctac
    28921 caagcaatat ctcaattgct tagaaaccac gtggcaagct tatcagaaaa gagaaaacct
    28981 tcagttatct gattttgctg cagtttgttt ccatattcca tttcccaagt tagccctaaa
    29041 aggtctaaat aacattatgg ataacacagt acctcctgaa cacagagaaa aactaataga
    29101 agcctttcaa gcttctatta cttatagcaa acaaattgga aatatttata ctggctcact
    29161 ttatctagga ttgttatctt tacttgaaaa tagtaaagta ttacaatctg gagataaaat
    29221 tggttttttt agctatggtt ccggtgccgt aagtgaattt tattccggtc agttagttgc
    29281 tgggtacgat aaaatgttaa tgactaatcg acaagcttta ctggatcaac gaacacgtct
    29341 ttccgtttct aaatacgaag accttttcta cgaacaagtc caattagatg ataatggtaa
    29401 tgccaatttt gacattcact taactggaaa atttgctcta acagccatca aggagcatcg
    29461 aaggatctat cataccaatg acaaaaacta atcttaactg gagcggtttt tcaaagaaaa
    29521 cattcgaaga acgcctccaa cttatcgaaa aatttaaact acttaatgct gaaaacttaa
    29581 atcaactcaa aacagacgtt cttttgccta tccaaacagc taatcaaatg actgaaaatg
    29641 tcttaggacg attggctttg ccctttagca tagctcctga ttttcttgtc aacggttcaa
    29701 cttatcagat gccttttgtc acggaagaac cttctgttgt tgctgcagca tctttcgcag
    29761 caaaactaat caaacgctca ggtggtttta aagctcaaac cctaaaccga caaatgattg
    29821 gtcaaattgt tctttacgat atcgaccaaa tagataacgc taaagccgcc atccttcata
    29881 aaacaaaaaa gctaattgca ttggcaaata aagcttatcc ttccattgtt aaaagaggtg
    29941 gaggcgctag aaccattcat ttggaagaaa aaggagagtt tttgattttc tatctgactg
    30001 ttgataccca agaagctatg ggagcaaata tggtcaatac tatgatggaa gctcttgttc
    30061 ctgatttaac aagactgtct aaggggcatt gtctaatggc gattttatct aattacgcaa
    30121 cagagtcgct tgttactact agttgtgaga ttcccgtgcg ccttttagat cacgataaaa
    30181 caaaatccct acagttagct caaaaaatag agctagccag ccgactagct caagtagatc
    30241 cttaccgggc tactactcat aataaaggta tttttaatgg cattgatgca gtggtaatag
    30301 ccacaggaaa tgactggcgt gctattgaag caggggccca tgcttatgcc tcaagaaatg
    30361 gtagctatca aggacttagt cagtggcatt ttgaccaaga taaacaagtt ctgcttggcc
    30421 aaatgaccct ccctatgcct attgctagta aggggggatc tatcgggctt aaccctactg
    30481 tttctatcgc acatgatctt cttaatcaac ctgatgccaa aacattagcc caattgattg
    30541 catctgtggg gttagctcaa aactttgctg cactaaaagc tctgacctca tctggcatcc
    30601 aagctggtca catgaaacta catgcgaaat cattagctct tttggcgggg gcaacccaag
    30661 acgaaattgc tcctttagtt aatgctttac tagctgataa accaataaat ctagaaaaag
    30721 cacattttta cttatctcag ctaagacagt cttagattta aacaactaat ataaggcaaa
    30781 cacccatgta aacaattggt ttacatgggt gtttaatctt tgtttctata catacaagtc
    30841 ttagaaatag tctccataac atactctatt tactcatcta ctctattctg agtttgatga
    30901 ggtatttata aatattttat attatgttct aaaaaagctc tatcatcttt gtagtaggtg
    30961 acactattgt agaggtgatg aagcctaatt gacctgctgc aagcgtccat atagtaagta
    31021 gtcgactccc tttaattctt taatagtttt acagtcaaga gcacacataa tgatttttaa
    31081 ttcttctttc cagccgttaa cgatagcaat cacacgctcg gttgggtatt tttcgaccaa
    31141 ttctaaaacg gtgcgtgaga gtcccactgc acgtgctcct aggacgaaac atttaatcat
    31201 gtccaagggg tgtctgacac cacccgaagc taagatttcc acttggtcca tcagtccttg
    31261 tgcattcagt aagcactgaa cggtggtttg tccccaatcg tttaagtaag agcggtctcc
    31321 tcctctttga ttttcaatat aggcaaatga ggtccctcct cttcctgaaa tatcaaaggt
    31381 ttgaatgcct aggtcatgtg ctagcttgat actattgaca tccatgccaa aaccaacttc
    31441 tttgagaatg acaggaactg gtatttgact agcgtattca gcgaggtgtt ttttccaggt
    31501 atgaaagacg cgctcaccct ctggcatcag caactcttgc atcacattca catgaacctg
    31561 taaaaagagg ggctgcattt cttgaaccgt ttgttgtcct agcgccacag gtttatctag
    31621 accaatattc gtggctagtt tcaagttatc tgccacctca tgtaaacgat aggaatcgtc
    31681 gttaggattt tttaaagcag cgctataaga ccctgtcacc atgacaatcc ctgttgctgc
    31741 tgctactttg gccaattttt cattgacagc tttgcctttt tgacttcctc ctgtcatggc
    31801 attgatgtaa aagggaaagt cgaagtcttg cccggcaaaa tgagtactga gatcaatatc
    31861 agacaaatca tagctaggta aggaatgatg tatgagttct atgtcatcaa aagcattata
    31921 aggcgattgg tacttgaggg catatttgat gtgatcatct ttacggttgg tcattctctc
    31981 cccacctttc ttgataaagt aatgcgatat cagcttcttg ccatttggaa ataagggtat
    32041 ctctggcatt ctgattaaag gcaagcgcga tgccacaatc tccaccacca gaacctgaag
    32101 atttagcaac agcatcttgc ttctgacaag cagctaccaa ggttactagc ttaggatggt
    32161 agatagtcgg atgaagctct tttaggagat gacttgctcc tgctaaactt ttcttgagtt
    32221 cttccttatg accttcttgc aaagctacca tagctgattg cgttagctgg taacttgttc
    32281 ttaagaaagc tggggtaatg ctcgctgtca cttgttgaat catctgcctt gaaatagcag
    32341 gtattttagt ccagccaacc aaaaagtcac aaggcagggc tggttgaatg acttggatat
    32401 ggtaacccca atctttgacg agaagttttt ttaagggcat ggtctgcagc cagttactga
    32461 cctgttctcg gtcaaaggag gtataggcga ctaaagtctg gtaagcgata caggcaatat
    32521 cccccataga cccattatct ccttgcttaa gcaaggtata agccgctagt ttaaagagta
    32581 actctggggt taaagtgatc tgataatagg ccgataaggc ctttaaggtt aagagggtga
    32641 cactaccact tgaaccaatg ccaaattttt tgccatcgcg ctccattttt cccgttataa
    32701 ttagggaaaa tggctccagt tggtcaattg actgtcctag ataatcagca aaggttttaa
    32761 ccgttgcttg aatcagtgca taagaggcat cgggtgtcat gcccgcttta tgggcaaaca
    32821 tatctgaagc taattgaata tgggctgctg ggctaatttc tgctgtcatc atcagtggaa
    32881 taaagtgaat taaggctttt tgtcctggtg ttaagatagc atattcgcct gtgaggtata
    32941 gtttcccacc tgtttgcaca caataattag acatctggta aatcctttgt ttttgaaacg
    33001 ataatacggt agttcttgcc aagtcgttct gctagttgag ccaagtcttt ttctaaacat
    33061 aggaccttca catttggacc tgcgtccatg gtaaaataac aagcaaaacc ttcttgacgc
    33121 agttctttca cagcctccat agcctggtaa gactcttttg ttaggtaaga aaagggagga
    33181 ttggctgtct ttgtcgtggc atgcatggcc aaggcattag cttctgttaa ctgaccaact
    33241 ttctcaaaat tattagtttt gagataggta agcatatgtt ggtaatcgat tgccgattgt
    33301 tctacccatt gatcaaatgt agttgaggta tcgcggcata acttcatgcc ctctcggcta
    33361 gaaattggct ttttcgcagc atttaagacc agcataatca tggccatttt caagtcagtc
    33421 tcaaccttgt aaatagcacc actatctttg tcccaagcag cgactgggcc aaaaaaagaa
    33481 cgagaagatg atcctgaggc gaacttagcc ttttgagcta aagctttctg atctagctgg
    33541 gtgtcaaata attgatcaca ggctttaacc aaggctgata agccactgga acttgatgat
    33601 aaacctgcag ctgttggcat attattttga gtttccatct ttacaaaagc ctgaccaggt
    33661 tggcgaaatt ggtcaatgat agcagaaatt ttggtatgtt cttcgtcatt ttgcaagaca
    33721 ccgttaatgt aaaactgatc actggttgca gtatctggta agaaggaaac gctggttgtg
    33781 gtgaacatgt tttccaaagt caaagaaatg ctagaggtcg aaggaatcat cttagcttga
    33841 ttctcttttc cccaatattt gataatagca atgttagcat aggatgttac ggttataaca
    33901 tttggatcca cgtgtttacg gctccttctt cttttaatct gtgactgatt ttttcggcca
    33961 tgtctttggt atctgctagg gcaatcatac agccacccaa gccaccgcct gtcatcttag
    34021 cgcctaaagc acctgctctt agggcagcct ccacaagttg gtcagcttta ctgatgctaa
    34081 cgccaatggc ctttaaagca gagtgcgctt gtgtcatgag ctgaccgata gccaccttat
    34141 ttttttggtt aatcgctctt tcaagggctt gtgtcaaagc tcctagttta gccagatagg
    34201 gcaaattcgt ttcctcaaac tgtgctacct tattgacggc ctcacgtgta tgaccgtgaa
    34261 tccctgtatc tgcaatgaca agataaccat ttaaggcgat ttcgatagtt tcaaagccaa
    34321 tgtttcggat aaacttaatg gcatggtcac taaggcatgt cttggcatct aaaccactag
    34381 gattggtgtg ggcaataatt tctgccttgt tgactaaaat ttccaacaaa tcatccgaga
    34441 ggggttcttg acaataagaa aaaacggctc taatagctgc aatagaaacg gctgccgaag
    34501 accccatacc acgcttttgt ggcacttgtg aaacaatctc ataagcaatt ggttcttgta
    34561 gtcgctgcaa ataatccaag gcagcataaa tggctgttga tagagtatca taaaaatcaa
    34621 agaccaatgg cttatcagct ggaaaaatat gacaaaccac ctcaatatct gttaaaggca
    34681 aagcaatagc tgggtagcca tacacaacag catgctcacc tatcaaaatg atcttactgt
    34741 gtgccttacc atatccaatg ttttcattca ttttttatct tttcattact aattcttcta
    34801 aacttttacc ttactatttt acactaaatg attagaaaat gcgatgatat atctttttaa
    34861 aatcatttct tcactgaaat taacaataaa gactatctac tctttttagg atcataacaa
    34921 aaattttctt atttcaaact accttcttta atcactcttc tactaaatta aacgttaaaa
    34981 ccagcctcat gggctggtta agcatcattt attacctttg cctagacatt attactagct
    35041 aaaggtactg aaaaatgttt aagttaaatc accactgtaa aaacaatagc atcgttttta
    35101 taatttacag ttatcgttcc tttaaataac ttaaccatac tttctgccat agataaacca
    35161 attccatagc ctttttcttt gctattatgg gattcgtctt cacgataaaa gcgttcaaaa
    35221 aagcggctgt aatcaatgga ttttccttcc aaataggtat tagaaacttc taatttcgct
    35281 cgttttcgtc ttcttccaat agtggttaaa gataccttga ccaagccttt aggatcacaa
    35341 tatttattgg cattatcaac taaaattgtc acaagttcaa ataatgactt ttcctccgct
    35401 ttaatcataa tattcggctg aatcgtcaaa tcaaaacgtt taccatcttt caaaaccaga
    35461 ctcttaaaat cttcagctgc atcttgagca atagctgaaa agtctaccat atgtaatacc
    35521 acatctggct gttcctccaa acgagccaaa gtaatcattt gattaatcaa gcctgtcaat
    35581 cgcttcacct gatcacttgt actcttggtc cattctgatt ctccagtcat taattcgacc
    35641 aattcattat tggctgagat aatggctaat ggtgttttta actcgtggcc tgcattagta
    35701 ataaagcggc gctgcttctc ataattttgg acaaaaggtt tgatgaccat accggaaaaa
    35761 agactcacta aaacaacaaa aaagataaat cctccaaagg ccaacatcat tgaaacagct
    35821 aataaatctc ctacactacg aaaataaaag gtagtatcta aaataacaac cagtttttct
    35881 tcatttggca gctgagtaat caagtacgaa taaacactat cttggtgacg gtaactgcct
    35941 ttttcttccc cagacttagc aaaaagtcta gcaaaatatt gggcttcttc tctatctaaa
    36001 gctgaaatat tagcagtatt agaagaaagt agatgtccat tagcattaaa aatgacacta
    36061 taataccgaa actggcttag gctatcttca gacagtttcg ttccaagtcg tttagagctt
    36121 tccgtagtgt caggtaattt acctttattt gaggaaatta aatgtaaaat acggttaatt
    36181 tcttgttgac tttggtaaca gcgtgccgtg ttaataatac caacaattga acttaaaata
    36241 ataaaaatgg caatagaagc aatcatgata aaacgaatac ggatacgatt aaacatgtca
    36301 cctcctattt ttctaataaa caatagctag tatctttatc acctgcaata atgacatttg
    36361 cttgaatagc taataatttt tgacgaagat aagaaatata aacccaaaca atagaagtat
    36421 cataatcttc ttggtctgac caaacatgtt ggtaaagtgt tttagtatcc aagtactttc
    36481 cttgatttaa cattaaaaag gccattaatt taccttcttt agaagctaat cgtatagcat
    36541 taccggcact cagttcttgc tcattaatat ttaatgtgac accagcaaat tgtaatacct
    36601 gaggagtaaa actttctact cgtctttcca tcgaccttaa tctagctaaa agttctttta
    36661 atgagaaagg tttagtcaga taatcatcag ctcccgcatc tagtccggta acacggtcat
    36721 taatttctgc catagccgtc agcataataa tatgtgagca atttcctgaa gcgcgaatct
    36781 cctttaaagc ctcaatgcca gacttaatcg gcatcatgat atctaaaatc ataatatcat
    36841 atgcattgtc tttggcttta tcaattgcct cttgaccgtt aaaaaccaca tcaacgtcat
    36901 aaccttgatg agtcatggca gttgtcaaaa cattagacat ctgccattcg tcttcagcta
    36961 ataaaatttt catggttact cttcctccgt cgtttcttga atcaattgac gaatggtttg
    37021 catggtaaca tcacaagatg ccaactcgtc tgcacaacgc tttaactctc ttgtaatcat
    37081 ttctgcatta gcaacttgat gtttgtactt catttgatgt tccaagctag cccaagagtc
    37141 ttgagcaatg gttcgcaact gcacttctat aaaataacat cctttttttc ccctaaaata
    37201 tctggaaaat gtgtttctaa ttccaaaatg agatgatatg atctatagcc attaggcttg
    37261 gcatttaaaa tataatcttt ttcagtgtta actgacatac caggaatgct tttgagcaag
    37321 tctaccatcc gataaatatc atcaataaaa ccacaaataa tgcgaatacc gatactatct
    37381 ttaatgattt ttaacgcaga tttgcttgtt agaggaagct gtttgcgttg acatttttca
    37441 atcatcgaag cttccgattt aatacgggat gtaaagtgtt cgtatagttt aaaccctgtt
    37501 tcttttttgc ttttgatatt ctcagcaata atcacatctg ttattgtctg tagtaccaac
    37561 ggcaagtaca cttcaaatcc gctatatata gagctggtag aataatgttc tagtctttct
    37621 ttcatacgct tattataaca aattttctca acaaatgctt aaatctctgc aatgatcggt
    37681 tatctttatt tctaactata taactgcaaa tgatctgtat cgtttgcttt taaatcgctt
    37741 tcatatattt tttgtacgtt attttttaaa aataccattg aattacaaac aaaaacatag
    37801 taaacttgat ctataacgat tacgttaact tattaggaga ttttatgaaa aaatatttta
    37861 ttttaaaaag tagtgtattg agtatcctga ctagttttac tctattagtt acagacgttc
    37921 aagcagatca agttgatgtg caattccttg gcgtcaatga ttttcacggc gctcttgata
    37981 ataccggaac agcttacaca ccaagtggta aaataccaaa tgctgggacg gctgctcaat
    38041 taggtgctta tatggatgac gctgagatag atttcaagca agcaaatcaa gacggaacaa
    38101 gtatacgtgt tcaagctgga gatatggtcg gagccagtcc tgctaactct gcacttttac
    38161 aagatgagcc tactgtgaaa gtctttaaca aaatgaaatt tgaatatggc actcttggta
    38221 atcatgaatt tgacgaagga ctagatgaat ttaaccgtat catgacaggt caagcgcctg
    38281 atcctgaatc aacaattaac gatatcacca aacaatatga gcacgaagct tcgcatcaaa
    38341 ccatcgtcat tgctaatgtc attgataaaa aaactaatga tatcccctat ggttggaaac
    38401 cttatgctat aaaagacata gccattaatg acaaaatcgt taagattggc ttcattggtg
    38461 ttgtgactac agagattcca aatctcgttt taaagcaaaa ctatgaacac tatcaatttt
    38521 tagatgtagc tgaaaccatt gccaaatatg ctaaagaact gcaagaacaa catgttcatg
    38581 ctattgtggt tttagctcat attcctgcaa caagtaaaga tggtgttgtt gatcatgaaa
    38641 tggctacggt tatggaaaaa gtgaaccaaa tctatcccga acatagcatt gatattattt
    38701 ttgcaggaca taatcatcaa tacactaatg gaactatcgg taaaacacgt atcgttcaag
    38761 ccctctctca aggaaaagct tatgcagatg tccgtggtac gctagatact gataccaatg
    38821 attttattaa aactccatca gcaaatgttg ttgctgtagc accaggtatc aaaacagaaa
    38881 attcagatat caaagctata ataaatcatg ctaatgatat tgttaaaaca gttactgaac
    38941 gaaaaatcgg aactgcaact aattcttcaa ctatttctaa aacagaaaat attgataaag
    39001 aatctcctgt cggtaactta gtaacaacgg ctcagcttac tattgctaag aaaacttttc
    39061 caactgttga ctttgctatg accaataatg gtggtattcg aagtgaccta gttgtcaaaa
    39121 atgaccggac catcacctgg ggagctgcac aggctgtaca accatttggt aatatccttc
    39181 aagtcattca aatgactggt caacacattt acgatgtcct aaatcagcaa tacgatgaaa
    39241 accagaccta ttttcttcaa atgtcaggtt taacatacac ttatacagat aatgatccta
    39301 agaactctga tacccccttc aagatagtta aggtttataa agacaatggt gaagaaatta
    39361 acttaacaac tacttacacc gttgttgtca acgactttct ttatggtggt ggtgatggct
    39421 tttcagcatt taaaaaaact aaattaatcg gagctattaa cacagatact gaagctttca
    39481 tcacatatat cacaaattta gaagcatcag gtaaaactgt taatgctact ataaaagggg
    39541 ttaaaaatta tgtaacttca aaccttgaaa gctcgacaaa agttaatagt gctggtaaac
    39601 acagtatcat tagtaaggtt tttagaaatc gtgatggcaa tatagtgtct agtgaaatca
    39661 tttcagacct tttgacttct actgaaaaca ctaataacag ccttggcaaa aaagaaacaa
    39721 cgacaaacaa aaatactatc tctagttcca ctcttccaat aacaggggac aattataaaa
    39781 tgtctcctat tatgacaatc cttgccttga taagcttagg tggactaaac gcttttatta
    39841 aagaaaggaa atcctagcgt ttactagtaa tcgatcaccc ttatataatc aggcatcttt
    39901 gccaaaaaaa cctaaagcgt cctactctag gttttttgtt aaattaaaat accttctaga
    39961 tgatctaatt cgtgctggca tatttgagca gttaagcctg ttaagcttaa tcgctttggt
    40021 cgccaattat ggtccaaata ctcaacagta atcttatcat accgctgtgt tttgcgatag
    40081 ccagataacg acaaacaaga ttctttagtt tggtaaattc cctttttaga aaccatcaca
    40141 ggattaaaca taaccaaatc aataaatccc atactcacaa taacaatgcg cttttgttca
    40201 ccaatcatat tggcagccat cccaagacat tcctgtctat aaaaggctaa ggtatcttgt
    40261 aaatcttggc caatccatag atcttctttc ttggcgactt gcgctttttg ctgtaataaa
    40321 aaatgatctg ttatgatttc tctaatcatt cttatctcct taaaccttct ttttaattca
    40381 taaactacat gttcaatgga ctattatcac catatgatag acttagtatc atctgtttaa
    40441 aacatcaggt gattccttat ttcaagatat cttgggcaac tttatgaaat tctgcaatat
    40501 gagtaccaaa taaaaattga cctgcatcag cagattgttg ctaagttctc atcacaatat
    40561 tatcgaattt actgtctgct tcttcaaatg tctaagagag atagttattg ctttgtgaga
    40621 ttttcaaacc agatactgct ttctcttgca tttgcagcct taacaggtcc aaataaaaca
    40681 cctgctgttt gaaatgcttt aatagctgat atgttgttaa tagttagtat tataaatttt
    40741 ctgaatattt ctgtcaagtt tttcagttga cttaactttt ttacttgatt tttcctcacg
    40801 taataataga aaagaagcgc cataatgtaa actacacccc aaacgttaga taaaaaaatc
    40861 taacgtttgg ggtgtttttg tatgacatta agctatgaag ataagctaga tatttagcgc
    40921 taaaaaaaac cgagggaact ccgtttgaaa gaagcatctc tgcaaagaag aagacaaaaa
    40981 accattataa agaatggaca aagacgagct ctgattagat tttcttttca gaacggctaa
    41041 agtgactcgt tctacctact attatcatcg attattgcaa caataaacgt atcaaaataa
    41101 aacgaaaagg acttagtcct ctacaacaca gaactaaatc ctttacttca aatagagtag
    41161 ccaacttttg gggctcagtg caagagcact tcttttctat tatcacttgt ttattataaa
    41221 cataacatta ccatagtata cttatatgtc tagtccactc aaatactcaa accgttcata
    41281 cgccaataat aaatcattat tgcgctgatc gagttccttt tgtaattgag ctaactggtc
    41341 ataatcacta actacagtta acatttggtt ttcaatttct tcaatattag cctcaatagt
    41401 tgctatttta tcttctatct gagcccattc ttgtttttca aggtaggaca tgcgcctttt
    41461 ctcctctttc ggaggaagtg gtacttcttc agtgactatt gctttagcta agtcagcttc
    41521 aactgtttct ttttcaaaag ctttttcatc aaggtaatca ctgtaattgc cataaaaaac
    41581 acgaatatcg ccttcttcaa aggctaaaat cttagtggct actttgtcta ggaaataacg
    41641 atcgtgacta accgtaatga ctggtcctgc aaagttagtt aaaaagtttt ctaagaccgt
    41701 caaggtggca atgtctaaat catttgttgg ctcatcaagg agaagaacat ttggcttttc
    41761 aatgagcagt tttagcaagt agagccgttt tttctcccca ccagataatt tagcaatcag
    41821 cgtgccatga cttgatctcg gaaaaagaaa ttgttctaaa agctcactga tactcgttgt
    41881 tcccacgctt gttttaacct catcagccac ttcttgaagg taattaatga cccgtttggt
    41941 ctcatccata tctttgagct gctgagagaa ataacctaca cgaatagtat ctccagtatc
    42001 aagcttccca gaagttggtt tgagatcacc gttgatgata tttaacaggg tagattttcc
    42061 gacgccgtta tctccaacaa ttccaatacg atctttattt tgaataatca agttaaaatc
    42121 cttaatcaac tgtcggtcgc cataagcaaa agaaaggtct tcaaagtgaa tcaccttctt
    42181 cccaattcgg ctcgtttcga aagccatctc caacttatcc gcagaactgt cttggtgaac
    42241 ttcttttttc aagtcagtga aacgattgat tctagcctgc tgtttggttg cacgcgcctg
    42301 tggctgcgtc ctcatccagg ctaattcttg tttatagagt tgcttcttct tgtgtaaatt
    42361 agcagcatct cgttcgtctt gttctgcttt taagcgcaca tagtcttggt aattgccttg
    42421 atattctgtc agtcccgctt tatccaattc aaaaatacgg gtagccacat gatcaaggaa
    42481 ataacggtca tgggtaataa aaaggacggt ttttttagct gtcttgagat aggttgttaa
    42541 ccaagcgatg gtatcaatat cgagatggtt ggtcggctca tctaatagga gtaagtcagc
    42601 agctcctagc aatacttgag ctagctggac acgtcttctc ataccacctg ataggtctcc
    42661 cactttttgt tccaaatccg tgatgcctaa ttttgatagg actgttttga catcactttc
    42721 aatagaccaa gcatctaagc gatccatttc agacatgagg gactctaagg tctcttgttt
    42781 atcttcagta taattcgcca tcaatagttc atactgacga atcagctgaa tcgccttaac
    42841 atcagctgac aataccgtat ctaaaacaga ggctgcatcg ttaaattcag gatcttgtgt
    42901 taagtaagcg attttgtaat cattggcttt agaaaatggt gaatggtctc cgtcaaaacc
    42961 aagccttccc gacaagacat ctaaaagagt tgtttttcct gtcccattaa ccccaataat
    43021 cccaatacgg tcaaagtcat gaataataaa ggaaatatct tgaaagacgg tcttatctcc
    43081 caccgttttt gtcaatttct ccaccaaaaa atggctcatg ttgctaattc ctctctaaca
    43141 aatgcttcaa ttgtagtgaa atcattatct aggcgcccct ctacaatcgc taattcaact
    43201 ttctcaagca taagccctag ctgaggacct ggtttcatcc caaaatcctt aatcaggtga
    43261 gaaccattaa ggacgatatc gtgtttgtca tgaataacca gtgcctgatc taaagtatta
    43321 atacgatcca tgtcaacgga taagctttga gcttttcgga ggtcttccac tagactcgcc
    43381 attttcttgc cgtactggta aatatccaat ttttcaaaag atctttcctg acgaattcta
    43441 taaagagcaa tcaactttgt gacataacgc tgaaaatcat ttgaagtctt ccatgctttt
    43501 aggaagcttt taggatcctc aatggctaaa ctaatcatca cataagccca agcttggtga
    43561 taatcactaa aggtaaagtt atctttcaaa gaaactatca gatgattcaa gcctgcttcc
    43621 tgctgcttca agcctggtaa atagtcgtaa gcctgacaag caatcatggc agaaatccct
    43681 tttcgccagt gcggtgccat caataattta tcaaattcag taaaagaacg ttccacagaa
    43741 attttttcca atagaggtga atggctcctc atagcttcaa aagttgtagc ttcaatgtca
    43801 aaatccagac tcgccgcaaa tcgaaagcct ctcataatgc gtagtgcatc ttcttcaaaa
    43861 cgttcctctg ctttacccac tgctcgtaac cgtttttgct ttaaatcaat gagtcctcta
    43921 aatttatcaa taacttgacc attttcatcc aaggccaagg cattgacggt aaagtctctt
    43981 cgttttaagt cttcctctaa agagcgcaca aaagaaacct gactaggacg gcgataatca
    44041 acatagacat cttctgtcct aaaggttgtg atttcatact caccgccatt ttcaagcacg
    44101 agcactgtac catgttcaat gccaacatcg acagttctgt taaaaatcgc tttagtctct
    44161 tcaggatagg aactagttgc aatatctaca tcatgaatgg gacgcccgag taaaacatct
    44221 ctgacgcttc ctcccacaaa gtaggcttca taaccagctt cttttatttt agtcaatatg
    44281 ggtaaagcct tctgaaactc agaaggcatt gtcattaatt tcatacgttg ttttctaacc
    44341 tatcatccaa ctagcccaat ctaaagtgtg attaggctac ttgggttcta tcacattttg
    44401 ttattgtttt agtgattctt gcaattaact attttttcta atcgacaatt aaagcctcgg
    44461 tgttacgcca aatgcaatgg ctccttctcc taaatgagta gcaatcaccg ctccaaaatg
    44521 aacctcttca atgtcatatt gataaccact gtcttgtaag agtcgtttca aataatcagc
    44581 tttgtcttgt gcttttgagt gaataataga cacattatac tgaccgtctg ctatcaagtc
    44641 atttaaaatc tcaaccaagc gtttcatggc tttcttttct gttctcactt tttcataaac
    44701 aacgattttt ccctcttcat caaagcgtaa aataggttta atactcaaaa gatttccaag
    44761 aagagcagac ccatttgaca ggcgtccgcc tttaaccaga tgattaaggt catcaaccat
    44821 aataaaggct gtcgtcccat caatctgttc ttgcagcttg tttaaaatag cttgaaatgt
    44881 cattccttga cgtgaccaat ctagcacatt ttttaccata ctacctaaag gagcagatgt
    44941 gatcttactg tctggaaatg ccatttcaat ctcaggatgt tcttcagcta aaaattgaat
    45001 attttgccaa aagcctgaga ttcctccagc taagaacaag ccaataacat gtgtataacc
    45061 cttagaagac aaaagcccta aaagattatc tagttcagat aaacttggct gacttgtctt
    45121 gggaagattt tgggagtcag ccatcttttg ataaaaatca tctatactca aatttcgacc
    45181 ttcaaaatag gtctcatcgt caatgataac tggtatatca aggctaaaaa tagctttatc
    45241 ttgtttcaga tctgttggta gtgttgctgt actgtcagta attactgcta atttcattaa
    45301 tttttaaact ccaaatgaat acctggacga tccaaggcaa tttctgtgac ttcataagtc
    45361 aatcgcttaa ccatgtctag caaaggagca gctaaggatt caacttcctc ttgcgtaaat
    45421 tcgcttggtt tatccactaa acgatctaaa atgcgaacca tttgtgagat gaccccacta
    45481 ataacaaatt cttctttgac aataacaaat tgcaatacag atacaattac tgtttctttt
    45541 tgctgctcat ctttatcaat caactgaaaa gtcacttcaa aattagtctc tggtgttccg
    45601 ttttcttttt cccactctaa atttctagca tcataatggt actggttgac aaattctttt
    45661 tcacgaacta attgcatttt ttattctcct tggtatcaat atgatccatt atagcataga
    45721 tttgaaaatt attaaagtag cccctaaact actattttcg cataacgttt taaacagtgc
    45781 tatctctcga acagatatct attttttcac ctatttatat ttagtcgtcc ttatactgac
    45841 attatatcaa aaaaacaccc gttagtggtc ttgtactgca cctcaattaa aacagaacca
    45901 ctggtcaggt aagttttaag tcaaggataa aaaggtttat cattaaggcc tcatcatgct
    45961 tagccaagta tttcgaacta gcttgtctta gctctagtcg ctcaaacgta aatcctaggc
    46021 gttcaatccg ccgcaaaacc tctccaacta acccatactt aaacccatcg ggcttaatca
    46081 tcgctccgcc cttcttcttt tatccattat aaaataaaaa cgttttaaca gacaaaaaat
    46141 aggaaagtac cagactattg gatttatttt tttatctcaa actccattaa cgatgttgag
    46201 ttaaaggcat tcaaaacaac atagatcgta agctaacaag attttttatc aattgaacct
    46261 atcgtcccca gttataccac gacctcttct ggatgaggtc tttttttatt tgtctaattt
    46321 catcaacgct tcttcccttc tttcttctat cacagctctc ctattgctca cttcctcatg
    46381 cagcaacata tcatcaaaaa accgttcatt tttaagcaca accactactg tatctcttgt
    46441 gatgtctcca ttgcaatcgc ttgtttaatt ttattaaaaa ttatttaaaa aattaaatat
    46501 tattttaaga acttgcaata atatatatct atattatata atttctttat cataaaatta
    46561 tatagaaaaa ggtattctta tgagaaaaag atgctattca acttcagctg cagtattggc
    46621 agcagtgact ttatttgctc tatcggtaga tcgtggtgtt atagcagata gtttttctgc
    46681 taatcaagag attagatatt cggaagtaac accttatcac gttacttccg tttggaccaa
    46741 aggagttact cctacagcaa acttcactca aggcgaagat gtttttcacg ctccttatgt
    46801 tgctaaccaa ggatggtatg atattaccaa aacattcaat ggaaaagacg atcttctttg
    46861 cggggctgcc acagcaggga atatgcttca ctggtggtta gatcaaaaca acgaaaaaat
    46921 tgaagcatat ctaaaaaaac acccagataa acaaaaaatc atgtttggtg atcaagaatt
    46981 attggatgta agaaaagtta ttaatactaa aggtgaccaa acaaatagcg agctttttaa
    47041 ttatttccga gataaagctt tccccggttt gtcagcacgc cgaattggag ttatgcctga
    47101 tcttgtttta gatatgttta tcaatggtta ttacttaaat gtttataaga cacagactac
    47161 tgatgtcaat agaacctatc aagagaaaga tcgccgaggt ggtatttttg acgccgtatt
    47221 tacaagaggt gatcaaagta agctattgac aagtcgtcat gattttaaag aaaaaaatct
    47281 caaagaaatc agtgatctca ttaagaaaga gttaaccgaa ggcaaggctc taggcctatc
    47341 acacacctac gctaacgtac gcatcaacca tgttataaac ctgtggggag ctgacttcga
    47401 ttctaacggg aaccttaaag ctatttatgt aacagactct gatagtaatg catctattgg
    47461 tatgaagaaa tactttgttg gtgttaattc cgctggaaaa gtagctattt ctgctaaaga
    47521 aataaaagaa gataatattg gtgctcaagt actagggtta tttacacttt caacagggca
    47581 agatagttgg aatcagacca attaaagcgt atcaataaga aagaatatct tcaacagatg
    47641 atggtattct aaggactaat actattgcag ggaatttttt tatagatggg caacagcaaa
    47701 aaacattaat aaatcctata aaaatcgat
//
LOCUS       DAUCXI010000012        47687 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.012, whole genome shotgun sequence.
ACCESSION   DAUCXI010000012 DAUCXI010000000
VERSION     DAUCXI010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47687
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.012"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(151..2361)
                     /locus_tag="VGY43_000665"
     CDS             complement(151..2361)
                     /locus_tag="VGY43_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEQ4301875.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLFGGALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIT
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILTQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNP
                     DEMTIAKTKEIRSAVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTKNRE"
     gene            2469..3632
                     /locus_tag="VGY43_000666"
     CDS             2469..3632
                     /locus_tag="VGY43_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEQ4301876.1"
                     /translation="MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNR
                     PIGTAYISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQ
                     EGDGFGGVTIDLYKDFAVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDT
                     ETAHLYGELAQETFSILENGIAYQVFLNEGLMTGIFLDQHDVRRALVDGLAMGKSLLN
                     LFSYTAAFSVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYF
                     KYAKRKKLIFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAA
                     NMTVSQFKKQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            3629..4315
                     /locus_tag="VGY43_000667"
     CDS             3629..4315
                     /locus_tag="VGY43_000667"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEQ4301877.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            4409..5575
                     /gene="aroC"
                     /locus_tag="VGY43_000668"
     CDS             4409..5575
                     /gene="aroC"
                     /locus_tag="VGY43_000668"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEQ4301878.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            5636..5977
                     /locus_tag="VGY43_000669"
     CDS             5636..5977
                     /locus_tag="VGY43_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEQ4301879.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASASELFDE
                     FVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            6199..7551
                     /gene="gorA"
                     /locus_tag="VGY43_000670"
     CDS             6199..7551
                     /gene="gorA"
                     /locus_tag="VGY43_000670"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEQ4301880.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHEAKVLLAEGKEIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKDKAFDFKQLKANRQAYIDRIHASYERG
                     FEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKAIVDVLVEEM
                     AVGGPCLHPHSEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFGLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSEHLFNNKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKKYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(7631..8908)
                     /locus_tag="VGY43_000671"
     CDS             complement(7631..8908)
                     /locus_tag="VGY43_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ4301881.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFPLIT"
     gene            complement(8938..9378)
                     /locus_tag="VGY43_000672"
     CDS             complement(8938..9378)
                     /locus_tag="VGY43_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301882.1"
                     /translation="MSSHYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITITRALQPVPDKTSNDTPKESSNTIVKIIEKESSQGNQNHTGTSETTDDNKTTLP
                     SSSTTPSHNETTPTAPETPSTTEGTQLPNATGAEDANTGLPTNP"
     gene            9613..10755
                     /locus_tag="VGY43_000673"
     CDS             9613..10755
                     /locus_tag="VGY43_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ4301883.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKNAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKALS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKHEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            10767..11981
                     /gene="thiI"
                     /locus_tag="VGY43_000674"
     CDS             10767..11981
                     /gene="thiI"
                     /locus_tag="VGY43_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEQ4301884.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVR
                     SDRDRTHVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQAINAVTSTPIIRPVVTMDKLEIIEMAQAIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            12019..13311
                     /locus_tag="VGY43_000675"
     CDS             12019..13311
                     /locus_tag="VGY43_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEQ4301885.1"
                     /translation="MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTM
                     ATVVALIVALLLFGLIYDLLGVQKNELAAQKSAQPKVKTARVVANGDILIHDILYMSA
                     RKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKN
                     TGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIKI
                     AILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQMGTEYA
                     LEPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRL
                     ETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTM
                     VLEDFIKGGKYHDKIDEETKAKVALAYQEINDLVNLKW"
     misc_feature    13416..13490
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            13525..13839
                     /gene="rplU"
                     /locus_tag="VGY43_000676"
     CDS             13525..13839
                     /gene="rplU"
                     /locus_tag="VGY43_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEQ4301886.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            13851..14177
                     /locus_tag="VGY43_000677"
     CDS             13851..14177
                     /locus_tag="VGY43_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEQ4301887.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            14205..14498
                     /gene="rpmA"
                     /locus_tag="VGY43_000678"
     CDS             14205..14498
                     /gene="rpmA"
                     /locus_tag="VGY43_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEQ4301888.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            14846..15760
                     /locus_tag="VGY43_000679"
     CDS             14846..15760
                     /locus_tag="VGY43_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEQ4301889.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLNDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            15757..16215
                     /locus_tag="VGY43_000680"
     CDS             15757..16215
                     /locus_tag="VGY43_000680"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEQ4301890.1"
                     /translation="MKKRLFVPSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMIHLDFMDFAIFNVADSYLTVGVILLVICLWKEEDYGN"
     gene            16205..17095
                     /locus_tag="VGY43_000681"
     CDS             16205..17095
                     /locus_tag="VGY43_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ4301891.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDALAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
     gene            17491..18012
                     /gene="pyrR"
                     /locus_tag="VGY43_000682"
     CDS             17491..18012
                     /gene="pyrR"
                     /locus_tag="VGY43_000682"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEQ4301892.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDTKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
     gene            18028..19287
                     /locus_tag="VGY43_000683"
     CDS             18028..19287
                     /locus_tag="VGY43_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEQ4301893.1"
                     /translation="MKDVSYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKAIGNDWIDNILPPIVVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPILLGLLVGYVVALLVGVFTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKILSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            19348..20283
                     /locus_tag="VGY43_000684"
     CDS             19348..20283
                     /locus_tag="VGY43_000684"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEQ4301894.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            20327..21409
                     /gene="carA"
                     /locus_tag="VGY43_000685"
     CDS             20327..21409
                     /gene="carA"
                     /locus_tag="VGY43_000685"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEQ4301895.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            21655..24831
                     /gene="carB"
                     /locus_tag="VGY43_000686"
     CDS             21655..24831
                     /gene="carB"
                     /locus_tag="VGY43_000686"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEQ4301896.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPTLDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSEAIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQDLQMHVEHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            25039..26310
                     /locus_tag="VGY43_000687"
     CDS             25039..26310
                     /locus_tag="VGY43_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ4301897.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNMLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANVKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGAAYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVTVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            26310..27020
                     /locus_tag="VGY43_000688"
     CDS             26310..27020
                     /locus_tag="VGY43_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4301898.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEIFNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            27032..28252
                     /locus_tag="VGY43_000689"
     CDS             27032..28252
                     /locus_tag="VGY43_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4301899.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGEGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVIGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            28506..30239
                     /locus_tag="VGY43_000690"
     CDS             28506..30239
                     /locus_tag="VGY43_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEQ4301900.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHVLLWMK
                     LFAINGLTLVVLSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDISHSKTVIAHR
                     GLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIRNL
                     TLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLETY
                     HRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFSYR
                     SYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIKDLKQDNSYF
                     SRLVRIISSLY"
     gene            30366..30638
                     /gene="rpsP"
                     /locus_tag="VGY43_000691"
     CDS             30366..30638
                     /gene="rpsP"
                     /locus_tag="VGY43_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEQ4301901.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            30648..30887
                     /locus_tag="VGY43_000692"
     CDS             30648..30887
                     /locus_tag="VGY43_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEQ4301902.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            31819..34845
                     /locus_tag="VGY43_000693"
     CDS             31819..34845
                     /locus_tag="VGY43_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEQ4301903.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSGPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQINSGSQLEQSKESLSLNKRVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPYGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVTGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKSFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTLGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STMVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDEAIAKAEKALVTKKATKNGQLLERSINKAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGSLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLIQLTSIRQVPT
                     AVYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSHPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLIAAIKKKKY"
     gene            34865..35266
                     /locus_tag="VGY43_000694"
     CDS             34865..35266
                     /locus_tag="VGY43_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEQ4301904.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINSESN"
     gene            complement(35446..36321)
                     /locus_tag="VGY43_000695"
     CDS             complement(35446..36321)
                     /locus_tag="VGY43_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEQ4301905.1"
                     /translation="MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCALHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLRESTTEKHCKKSIRLICQRYNINSVTVEIDTSLN
                     EHQHHCSSLSSIKVN"
     gene            36457..36978
                     /locus_tag="VGY43_000696"
     CDS             36457..36978
                     /locus_tag="VGY43_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ4301906.1"
                     /translation="MTKDRQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHILKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFVETLKWWLHQRQRMS
                     ANELLKYYLELIK"
     gene            37193..37711
                     /gene="rimM"
                     /locus_tag="VGY43_000697"
     CDS             37193..37711
                     /gene="rimM"
                     /locus_tag="VGY43_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEQ4301907.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DRFVQEVTIVSHRKQKHFDIIKLKDMYHINAIEKYKGYTLKVSKDNQGDLQEGEFYYH
                     QIIGMAVYEKDRLIGYVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLNVDVPNKRV
                     DVELMEGLDDED"
     gene            37701..38432
                     /gene="trmD"
                     /locus_tag="VGY43_000698"
     CDS             37701..38432
                     /gene="trmD"
                     /locus_tag="VGY43_000698"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEQ4301908.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTYLRRPDLL
                     ERYDFSEEERKLLDKIKEALGQGED"
     gene            38432..39424
                     /locus_tag="VGY43_000699"
     CDS             38432..39424
                     /locus_tag="VGY43_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ4301909.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGAELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            39602..40660
                     /locus_tag="VGY43_000700"
     CDS             39602..40660
                     /locus_tag="VGY43_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEQ4301910.1"
                     /translation="MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            40673..41596
                     /locus_tag="VGY43_000701"
     CDS             40673..41596
                     /locus_tag="VGY43_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEQ4301911.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     IVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPSNQEAGHQV
                     ADLLNEANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVKLNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
     gene            41852..42565
                     /locus_tag="VGY43_000702"
     CDS             41852..42565
                     /locus_tag="VGY43_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ4301912.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQFIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAARLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            42562..43473
                     /gene="pfkB"
                     /locus_tag="VGY43_000703"
     CDS             42562..43473
                     /gene="pfkB"
                     /locus_tag="VGY43_000703"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEQ4301913.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDITSTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELN
                     GQGPIISREQLEELKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
                     DFEGQTLIDALTYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            43470..45416
                     /locus_tag="VGY43_000704"
     CDS             43470..45416
                     /locus_tag="VGY43_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ4301914.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMIREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGNTYHAKNGKSET
                     AVSTEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSY
                     HEIAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            45509..46108
                     /locus_tag="VGY43_000705"
     CDS             45509..46108
                     /locus_tag="VGY43_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ4301915.1"
                     /translation="MKVKKRRRRAKSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDSLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK"
     gene            46259..46966
                     /locus_tag="VGY43_000706"
     CDS             46259..46966
                     /locus_tag="VGY43_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEQ4301916.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSAAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
     gene            complement(47023..47334)
                     /locus_tag="VGY43_000707"
                     /pseudo
     CDS             complement(47023..47334)
                     /locus_tag="VGY43_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(47538..>47687)
                     /locus_tag="VGY43_000708"
     CDS             complement(47538..>47687)
                     /locus_tag="VGY43_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ4301917.1"
                     /translation="HSKNRKHEKINLYDAKPNSTRSDVLKKYKDNKTINMKDFSHFDI
                     YLWTK"
BASE COUNT        15159 a         7832 c         9879 g        14817 t
ORIGIN      
        1 gtgggatatt tagatggtag caagaagttt tatagttgat ttgttttctt taggtctaat
       61 tagcatattt tgattactga taaacttgaa tatcgccaat aaaaaagaag caaaattatt
      121 attttgcttc tagtcagatc attaaattga ttattctcta tttttggtgt tatcctcttt
      181 tagttcagaa gttgccgcgt cagcttctac gggatttagt tctaagtaag atggtgcttt
      241 aaaaagtttc tgagttgatt tatgaccatt tttactgtat aaacttgttg actctgatcc
      301 gagttttgct gaaatatctt tcagttgttt taactgctta gtgtagataa actggttagg
      361 atcaatagct tttagaccat tttgagtatc aaagcgcagg agatcacccg tttgaatagc
      421 gtcgctagct gctagttgtt gagcaacagc agagcgaatt tccttagttt tggctatagt
      481 catttcatcg ggattagtga tttctaaacc tgtttgcgtg ttgtacagac gtccactata
      541 gttagtgtat tcaggagtca tataagtccc agatgttcgt tgtgccacaa tctggctatt
      601 ttgaggtgat aataaatctt gtcctaattg aacaaactga ctagtgtcaa taccaagtat
      661 gtggagtaaa gtaggaagag catcgatttc accgccaaag gtttctttga tactaccatt
      721 cgtataacct ggaatatgga tcatatacgg gactcgttgt agcatagcat tatcatattc
      781 agaccaagtt tcagaatctt taccaagaag tggagcaaga ctagaattac gagaatttga
      841 aataccataa tggtcaccat ataaaacaaa aatagaattg tcgtacaaac cagtggcttt
      901 caagtaatca aaaaaagatt taagggcagc gtctaaataa ttggcagtag caaagtaacc
      961 attgatcgtt tcatcgtctg ttttggctaa aggaaaacct tcttcactac tttcgccttt
     1021 tagactagta taaggatagt gattactcac agtgataaac ttggtataaa aaggttgttg
     1081 catctgttca agatatttta tggaatcctt aaacatgtac ttatcattta acccatattg
     1141 aaaagagttc ttactatttt gtttagagaa gtagctagaa tcaaaaaaat aattatagcc
     1201 ccattgttta taagcattat tgcgattcca gaaagttcca acgttaccat gaaagacagc
     1261 gctggtatag ccaccttttt gggttaaaat acttggagta gcaaattgtg tattttcacc
     1321 accgtagttc accataaaag aaccactatt taaaccaaat aaggaattct ccatcatggt
     1381 ttcagcatca gaagttttac ctgctttaac ctgatgaaaa aagttaggga atgctaaggt
     1441 agcatttgag tgataaagcg agttgataaa aggcgttacc tcatattctt tatctccttc
     1501 ttttagttta taatctatta agaattgttg aaagctttct aaatgaagaa caataatatt
     1561 tttgcctttt ccaattccaa aatactgagg atcaggtgct gcataatgtc ctttgacata
     1621 agttttaaca tcaattaatt cttctgcagt agctccattt cgttcttttt gagcttgata
     1681 ggtttgattg ccgctataga gggtaaacgc tggtagtcct aaagctctca caatataagt
     1741 atttgaaaag ccacgtgtta atagttccgg acgatcaatt tctgctaaaa aaagattaat
     1801 agaaagcaat agactagata aagcggtgat ggcaaatgct gcgcgcttgt taaaaggacg
     1861 ttggtcattt ttgatttttt tagtgataga taaactaatt agaataataa aatcaagaat
     1921 atagataata tcccagatgc gtaaaaggtt taaagcagag tcccctaatc cagcggagac
     1981 tttactacta gctagcatgg cactcactgt aataaagtct gaaaattctc ggtaatatat
     2041 agaatttgat atcaagagaa tgttaaggat aatataaacc acccaagaac agatataaaa
     2101 ggctcgggta ttcttaacgt aaagagcacc cccaaaaagt aaaaaagcta gtgggattgg
     2161 attgataata gttagaaaga cttggtatat atttcccaaa tctagtgaaa agtctgtatg
     2221 atatgcccac agggtcttta tccagtaaca aaagagtaga gtaattataa aacccaatct
     2281 tgtgttgata aaacctgtga taagtgtttt aaatttcttc acagtagcaa cttccttatc
     2341 gttttttcct aaagatgtca tctccaaata aaatctcaga ttaaattata ccaaaaatgt
     2401 gaagctaatg cttgttgtaa gttcaaattt agtaggattt tttatcagat tttgttataa
     2461 taaaaactat gaataaactc tatattgatt cttttgtcga aaagaagctg acagcagggg
     2521 tacaattatt agatgaaaaa gatttttcta atataaagga aaaaaatcag ttggttcaac
     2581 tggtgaccaa gtccaatcgt cccattggaa cagcatatat ctctaagcaa aataaaggaa
     2641 ttggttggta tctaggacca gaaaaaatcg acttgtctat ctcttatttt gttagtctat
     2701 tttcagttgc taaggccaaa agacaagatt ttgctcaatc ggacgagacc aatgcttatc
     2761 gcctttttaa tcaagaagga gacggttttg gtggagtaac aattgatctt tataaagatt
     2821 ttgcagtctt ttcatggtac aatgcctttg tctatgacaa aaaagaaatg attatggagg
     2881 cttttcaaca ggtttttcct gaagtcaaag gagcttatga aaagtgtcgc tttaaaggtc
     2941 cagatactga aactgctcat ctgtatggtg agctggcaca agaaaccttt tcgattttag
     3001 aaaatggcat agcctatcaa gtcttcttga atgagggctt aatgacaggt atttttctag
     3061 accagcatga tgttagaaga gcactagtag atggtttagc tatgggcaag tcccttctta
     3121 acctattttc ctatacggct gccttttctg tagcagctgc tatgggtggt gctatcgaga
     3181 ccacttctgt ggacttggct aaacgatcga gagaattatc actagctcat tttgagcata
     3241 accagttaaa cttagcctca catcattttg tggtgatgga tgtttttgaa tacttcaaat
     3301 atgccaaacg gaaaaaatta atctttgatg tgattgtgat tgacccacca agctttgcta
     3361 gaaataaaaa acaaactttc tctgtgagca gggactacca caaattaatc acagaggcct
     3421 tggacatatt gagtcctaag ggaactatta tagcttcaac aaatgctgct aatatgactg
     3481 ttagccagtt caaaaagcaa attatcaaag gatttggaag tcgtcgtcct gagtctatga
     3541 ctctccagca gcttccgagt gactttacta tcaataaagc agatgaaaga agtaactatt
     3601 taaaggtatt tactataaag gtacgagaat gagaattgta gcaccagtca tgccaagaca
     3661 ttttgacgag gctcaagcca ttgatatttc taaatatgaa gatgttaatt taattgaatg
     3721 gcgagcagac tttcttccca aggatgagat tgtcgcagta gcaccagcta tttttgaaaa
     3781 atttgccgga aaagaaatta tctttaccct tcggaccgtt caagaagggg ggaatattac
     3841 cctttcaagt caggagtatg ttgatattat caaagaaatc aatgctattt ataatccaga
     3901 ctatattgac tttgagtatt ttacgcacaa gtcagtattt caagaaatgc ttgattttcc
     3961 aaatcttatt ttgtcttatc acaactttga agagactcct gaaaatttaa tggaagcttt
     4021 ttcagaaatg accaagttgg caccgcgtgt ggttaaaatt gctgtgatgc cccagagtga
     4081 acaagatgtt ctagatttga tgaactatac cagaggcttt aagacgctca atcctgagca
     4141 agaatttgca actatatcta tggggaaatt aggaagattg tctcgttttg cgggagatgt
     4201 cattggctct tcctggacat acgtttcatt agatcatgtt agcggtccag gtcaagtgac
     4261 tctcaatgat atgaaacgta ttattgaggt cttagaaatg gatatctcta actagtgaat
     4321 ggtctaaaaa tattatttct acaatagtta agaaatgatg tttttagatt aatgttttta
     4381 aaataagtgg aaccaaaaag gagaaaaatt gcgttattta acagcaggag aatctcatgg
     4441 gccatcctta acagctatta ttgaaggtat accagcagga ttaactcttc atccagcgga
     4501 tattgatcac gaattacagc gacgtcaagg aggttatggc cgtggtgcca gaatgtctat
     4561 tgagactgat cgggttcaaa tatcctcagg agttcgtcat ggcaaaacaa caggggcccc
     4621 cattacctta acggtaatta ataaggacca ccaaaaatgg ctagatgtca tggctgtagg
     4681 agacattgaa gagactctca agttaaagcg tcgtgttaag catcctagac caggacatgc
     4741 ggatttggta ggaggtatta aatatcattt taacgattta agagatgctt tagagcgttc
     4801 ctcggctaga gaaacaacga tgagagtggc tgtaggcgct gttgctaaac gtatcttagc
     4861 tgaacttgga attgatatgt tacatcatat cttaatattt ggtggtataa cgatcacaat
     4921 accttctaag ctctctttta gagagttgca agaaagggct ctccattcag aattatctat
     4981 tgttaatcca aagcaagaag aagaaattaa aacgtatatt gataagataa aaaaagaagg
     5041 ggatactatt ggtggtatta tcgaaacgat agttcaaggg gtgccagcag gtcttggatc
     5101 ttatgtccaa tgggataaaa aattagatgc caagctggct caagcagttc tttccattaa
     5161 tgcttttaaa ggggtggaat ttggagttgg gtttgatatg ggattccaaa agggctctca
     5221 ggtaatggat gaaatcacct ggacacctac ccaaggctat ggtcgtcaaa caaaccactt
     5281 aggtggcttt gaaggtggca tgaccacagg acaacctctt gttgttaaag gggttatgaa
     5341 gcccattcct actttgtata aaccactcat gtcggtagat attgatagtc atgaacctta
     5401 taaagcaacg gtggaacgct ctgatccgac ggccttacca gctgcagggg ttatcatgga
     5461 aaatgtggtg gcgacggtgc ttgccaaaga gattttagag actttttctt ctactaccat
     5521 gtctgaattg caaaaagctt tttcggacta tcgtgcctac gtcaagcaat tttagatagc
     5581 gagatactgg cttttatggt atcatacagg tattaataaa caaaaggaga ctgtcatgtc
     5641 acaagaaatt tatgactatg ctaatcaact tgaaagagca gttcgtgctc tgccagaata
     5701 ccaaaaagtg ttagaagtaa aagaggccat tcaagcagac gctagtgcta gcgaactgtt
     5761 tgatgagttt gtcgctatgc aagaaaaaat ccaagggatg atgcaatcag gccaaatgcc
     5821 aacggctgaa gaacaaacaa gcattcaaga acttagccaa aagattgaag ctaatgacca
     5881 gctaaaagct tattttgaag cgcagcaggc cttatctgtt tacatgagtg atattgagcg
     5941 tattgtattt gctccgttga aagatttagt caagtaagcc aattaagata ggaaaaaaaa
     6001 cagattgctg gcagctcgtc aggatctgtt ttttagtgtt tattttcttt gtatcagaaa
     6061 gttgagcctc tttcttattt gtgatatagt caaataaatt gaccaaaata gcaggccagt
     6121 agtggcttta atgaaggcaa gttgtctgct aactggctat gctaaaacat cagtattaga
     6181 aagtaaaagg ttataaaaat ggttattcct tatgattata ttgttattgg tggagggagt
     6241 gcaggtattg cttctgcgaa cagggcagcc atgcatgagg ccaaagtatt gttagctgaa
     6301 ggtaaagaga ttgggggaac ctgtgttaac ctaggctgcg ttcctaaaaa agtcatgtgg
     6361 tatggcgctc aagtagcaga tattttaggg acttacgcta aggattatgg atttgacttt
     6421 aaagacaaag catttgattt taaacaattg aaagcaaatc gtcaagctta tattgatcgg
     6481 attcatgctt cttatgagcg aggctttgag cagaatggtg ttgaccgtat ttatgattat
     6541 gctgttttca aagatgctca tacggtagaa attgcagggc agctttatac cgcaccgcat
     6601 attttgattg ccacaggagg acatcctgtt tttccagata ttgagggggc acaatacggt
     6661 atcagctcgg acggcttttt tgccttagat gaggtaccaa aacgtacggc tgtggttggg
     6721 gcaggctata ttgctgtgga acttgccggt gttttgcatg ctttggggtc gaagacggat
     6781 ttgtttatcc gtcacgatcg acctttaaga agttttgaca aagccattgt ggatgtttta
     6841 gttgaggaaa tggcagttgg tggtccttgc ttacaccctc attcagaagt ggcaaaggtt
     6901 gtcaaaaata ctgatgagtc cttgaccctt tacctcaaag atggccaaga agttgaggtt
     6961 gaccagctca tttgggctat cggtcgcaag cctaatctag aaggttttgg tcttgacaaa
     7021 actggagtga cgttaaatga taaaggttat attgagacag atgcctatga aaacacgtct
     7081 gtcaaaggta tttatgccgt gggagatgtt aatgggaaac tggctttaac tccagttgct
     7141 gtggcagctg gacgtcgcct atcagagcat cttttcaata acaaaacaga cgagaaattg
     7201 gactaccaaa acgttgctac tgtgattttt agtcaccctg ttattggctc tgttggcttg
     7261 tcagaagaag cagcagtcaa aaagtatggg caagaagcag ttaaaacata tcaatcacgt
     7321 tttacgtcta tgtttactgc tatcactaac catcgccaac cttgtctgat gaagttggta
     7381 acagtcggag ataccgaaaa aatagttggt cttcacggaa tcggctatgg ggttgacgaa
     7441 atgattcagg gctttgcagt agctatcaaa atgggagcaa ccaaggcgga ttttgataac
     7501 accgttgcta ttcacccaac tggctcagaa gaatttgtca ccatgcgcta aaaaatgtag
     7561 cctaaggcaa taaaaaatga tgttaacagt tttcgaggaa agtcttctaa actgctagca
     7621 tcgttttttg ttaggtgatt agggggaata tgtttttaaa gatatttgcg ttgctcagac
     7681 aatattgcct tacctcggag ataaaataaa gtgaccctgt aacaacaaag agttcatcag
     7741 atgttacgga accttgtaac cagtctctgt aatcttttac ctgtgggtat ttatcaggat
     7801 aatcctctaa aagatttgct tcagggaaat caaaagtcgt gacagatact tcaaaagtat
     7861 ctagttgagc cagcaagtcg gctaaaggct tacgtttgag acctgcaaag aggatatgaa
     7921 taggacgttt gggaaattct tcttgcagta aagactttaa tttagcaatg gaatctggat
     7981 tgtgagcgcc gtctaataga agattaggtt gaataaattc ggaccggcca ggccaagttg
     8041 ttgcctcaat tcctttttga atcgtttttg gagatatttt aggaaaggat tttctaagta
     8101 attgagctgt cataatggct aaacaggcat tcgctttttg atgttgacct aatagtttga
     8161 gacggagttt ggttaaattc aagttatcgt gttgaaagga aaacgtcttt tctgaaggat
     8221 tgagcaaaaa atcttttcct aattgatata agcgtgaacc ggctttttgg gtaacttgtt
     8281 gaaagacttg actagcctcc tgctcaagtt gaccgataat aacgggttct ttagctttga
     8341 taacttctgc tttttggtga gcaatttctg ctaggctata acctaaacgt tcttggtgat
     8401 caaaactaat ggaagggcat acgacggcca gagcatgaaa aacattggtt gcgtcggttt
     8461 tcccaccaat ccctgcctca ataatggcaa tatcaacagg tttaagattg gcaaagtagc
     8521 aaaacattat gagagtcact aactcaaact cggtaggtct atcccaattt gtttcaaggg
     8581 acattttagt gagaatgggt ctaatcacgc tcacacattg cgccaattct aggtctgaaa
     8641 tgggctggcc attaaggcag atccgatcgt gaaaagagat gataaaagga gatgtaaagg
     8701 ttccgacctg ataaccagaa gttgacagga tatgctgtaa gtaggctgtc acagagccct
     8761 tgccgttagt tccaacaacg tgaatagcag ggaatttgtc ttgtggccgg cctagtgcct
     8821 caagtaacca agccattctg gccaaatcgg tcttgcgacc attagcctta aaggtatgaa
     8881 tccaggaaat gctatcatag gtagtcatta ctatttcttg tccttctaac aatgcttcta
     8941 agggttcgta ggaagaccag tattagcatc ttcagctcca gttgcattag ggagttgcgt
     9001 cccttcagtg gttgatggtg tctcaggggc tgtaggagtt gtctcgttgt gagaaggtgt
     9061 ggtagaagat gacggaagag ttgtcttatt atcatctgtg gtttctgaag tacctgtatg
     9121 gttttgatta ccctgagaag actctttttc aataatcttg acaatggtat tactcgattc
     9181 tttgggtgta tcattagagg tcttatctgg tacaggctgc agtgctcttg taatggtaat
     9241 ggttgccaca atgatactca aaatactacc aataagtgca atggattttt ggaaagctgt
     9301 aaaacctgtt ttaatatgct cggtagggac acctcctgat ttacgaggtt tttgttgacg
     9361 ggaataatgt gatgacatat ttttctcctt taaaatcatc gtaatgccaa gattaaggag
     9421 gaggaaatag aagtcctagc tcctctttaa cacttcatct atcagtataa tctagaaaaa
     9481 aagtgaagtc aacggtttac cttatgtcta ggacaaggaa gtcctttggg cttattgtaa
     9541 tacgaatatt cttgatttca ttttagctat tttgtgatag aataaagtat tgagtaaaaa
     9601 tgaaggtgac acatgattta ttttgataat gcagccacaa ccatacctta tggagaggct
     9661 cttaaaactt accaagaagt agcaacaaaa atatatggca atccctcaag tctgcaccaa
     9721 ttagggacaa atgcgtctcg cattttagaa gcttcccgta aacagattgc tggtttgttg
     9781 ggtgttaagt cagaagaaat cttttttacg tctggtggga ctgaaagtgc taattgggct
     9841 attaagggaa ttgcttttga aaaaaacgct tttggcaaac atattattat ctcagccatt
     9901 gaacaccctg ccgtgagtga aagtgtcaaa tggcttctca cacaaggatt cgaagtttct
     9961 tatgctccag tgacaacaca gggagttgtt gatgtgaatg ctttagctga gctgattaga
    10021 ccagacacca tcttaatctc gattatggct gttaataatg aaatgggagc tatccaaccg
    10081 attagagcca tttcaaacct attggctaac caaccaacga tcacctttca cgttgatgct
    10141 gttcaagcca ttggtaaaat accactctgt gattatatga ctaatcgtgt ggatttggct
    10201 tctttttcag ggcacaaatt tcatagtgtt cgtggtgttg gcttccttta taaaaaagca
    10261 ggcaagcgac tcaatcctct cttgtcaggc ggcggccaag agcaggagtt acgttcaacc
    10321 actgaaaatg ttgcaggaat tgctagcatg gccaaagcat taagaatagt cactgaaaaa
    10381 caagtgagcg tcttacctaa actaacagcg atgcgagatg tgatttacaa agctttgtcc
    10441 gcttacccag atgtgacagt attttcagct caagaaggct ttgcgcccaa tattttgacc
    10501 tttgggatta gaggggttcg aggagaagtt attgtccacg cctttgaaaa acatgagatt
    10561 tatatttcga ccacaagtgc atgttcgtcc aaagcaggta agccagcagg aagcctagtg
    10621 gctatgggga ttcctgtaaa aactgcccag acagccgttc gtattagtct agacgatgac
    10681 aacgatatgg gacaagtaga gcagtttttg accatattca aacagattta tgataaaaca
    10741 cagaaagtta ggtaagatta ggtaagatgg actattcaga aattatggtt cgccatggtg
    10801 aactatcaac taaagggaag aatcgcatgc gattcattaa caaacttaaa aacaatattc
    10861 aagacgtact ggctcctttc ccagccatta ctgtccgttc agatcgtgat aggacccatg
    10921 tgtctctaaa tggcacagat tatcagccta ttgtagaagc tttaaagctg gtgtttggtg
    10981 ttcaagctct atctcctgtt tataaacttg aaaaaagtgt ccctcttttg gtaacagctg
    11041 ttcaagatat catgacttct ctttatcgtg atggactgac gtttaagatt gccactaagc
    11101 gtagtgatca cgcgtttgaa ttggatagtc gtgagcttaa cagccttctt ggtggagctg
    11161 tttttgaggt tttacccaat atccaagccc agatgaaaca tcccgatgtg actctcaaag
    11221 tcgaaattcg tgatgaagca gcttacattt cttatgaaga gattaaggga gcaggcgggt
    11281 taccagtagg aacgtcaggg aaagggatgc tgatgttatc gggcggtatt gattcaccag
    11341 tagctgggta tttagccctt aaacgtggcc ttgatattga agttgttcat tttgctagcc
    11401 ctccgtacac cagtccaggt gccttggcta aagcccaaga ccttactcgt cggttaactc
    11461 gttttggtgg aaatatccaa tttatcgagg ttccttttac agaaattcaa gaagaaatta
    11521 aaaataaggc accagaggct taccttatga cattaacccg ccgctttatg atgcgcatca
    11581 cagatgccat tcgtgagcaa cgtaagggtc ttgttattgt taacggtgag agcctaggtc
    11641 aggttgctag tcaaaccctt gaaagcatgc aggccattaa tgcggtaacc tcaaccccaa
    11701 ttattagacc agtcgtgaca atggataaac ttgaaattat cgagatggct caggcgattg
    11761 atacttttga catttctatt caaccgttcg aagattgctg tactattttt gcaccagacc
    11821 gtcctaaaac caaccctaaa ctaggtaatg ctgaaaaata tgaagaacgc tttgatattg
    11881 atggtcttgt ccagcgtgct gtgtcaggaa ttgttgtcac agaaatcaca cctgaaatcg
    11941 tcaatgatga ggttgaaaat ctcattgatg ctttacttta aaagaaaaga tcaagtgtaa
    12001 atcttttagt agtcagtaat gatactattg aaaagcctct ataagggctt ttttgctgca
    12061 atgaaggagg aaaattttga ggcaagatgt tataatagag aaaaaggagg gtgtgtcttg
    12121 attaaaacta tgcaatacaa aaaaacgatg gcaacagttg ttgctcttat cgtcgcactt
    12181 ttgctatttg gcttgattta tgatttactt ggggttcaaa aaaatgagct agcagctcaa
    12241 aaatctgctc agccaaaggt caaaacagcg cgtgttgtag ctaatggcga cattttaatt
    12301 catgatattc tctacatgag tgctagaaaa gctgacgata cctatgattt cactccttat
    12361 tttgaatatg ttaaggactg gattagcggt gctgacttag ctattggaga ttatgaaggg
    12421 accattagcc cagattatcc cttagcaggc tatcccttat tcaatgctcc agaagagatt
    12481 gcaggtgctc tgaaaaatac tggctatgat gtagtcgatt tagcccataa tcatatctta
    12541 gattcccaat tagacggtgc ccttaacact aaaaaggttt ttcatcaatt aggtatagac
    12601 agtattggca tctatgacaa ggatcgttca aaagaatcct tcttaattaa aaatgtcaat
    12661 ggtatcaaaa ttgcaatttt aggttattct tatggttata acggcatgga ggccacactt
    12721 agccaagaag actatgagaa acacatgtct gatttagatg aagctaagat aaaaaaagaa
    12781 cttcagctag ctgaaaaaaa ggctgacgtg accattgtca tgccacaaat gggaacagaa
    12841 tatgccttag aaccgacagc agagcaaaaa gaactttacc acaaaatgat tgattgggga
    12901 gctgacgtcg tcctaggagg ccatccgcat gttattgaac cttcagagac agttataaaa
    12961 ggtaggcaaa agaaattcat tatttactct atgggaaatt ttatttcaaa tcagcggctt
    13021 gaaaccgtag atgatatctg gactgagcgt ggcctattga tggaccttac ttttgagaaa
    13081 aaagataaca aaacaaaaat taaaacagtt gaggcccatc caaccatggt tttagccaaa
    13141 ggtaaaggca ttgtgggtaa agaaggtttt gaactataca attatcgaac aatggtttta
    13201 gaagatttta tcaaaggtgg aaaataccac gacaagattg atgaggaaac caaagcaaaa
    13261 gtagcacttg cttatcagga aattaatgat ttagttaacc tgaaatggta atgtttggtg
    13321 gtttagcatc taacgataaa aaatagagat taaacttaat ttttccttga taaaaagcag
    13381 ttatggtgct aaaatagtaa cgttgactaa atgcacatcc tgtgcaaccg cgcgaaaatc
    13441 gttgtcaagt agaccaagtc tcacgattcc aggcgagtct tcacagaggg aaacctcaaa
    13501 caaaaatttt ataggaggtg catcatgagc acatacgcaa tcatcaaaac tggtggaaaa
    13561 caagttaaag ttgaagtagg tcaagcaatc tacgttgaga aaattgacgc tgaagctggc
    13621 gcagaagtca cttttaacga agttgttctt gtaggtggtg acaaaactgt agttggtact
    13681 ccagttgttg aaggagctac tgtcgttgga actgttgaaa aacaaggaaa acaaaagaaa
    13741 gttgtaacat tcaaatacaa acctaaaaaa ggtagccacc gtaaacaagg tcatcgtcaa
    13801 ccttacacta aagttgtcat caacgcaatc aacgcttaat ttactagctt atgattaaag
    13861 caatttttac tcgccaaaaa aatggtcaac tgagcagtgt tacactgaca ggtcatgctg
    13921 gtagtggtaa acatggcttt gatattgttt gtgcctctgt tagtactcta gccattaact
    13981 ttgttaattc tcttgaggtg ttagcagatt gccaagcatt agtagatctt aatgatgttg
    14041 aaggtgggta tatggctatt acaataccac cacatgacaa caaggaggaa gttcaattat
    14101 tatttgaatc ttttcttcta ggaatgacca gtttggcgaa ggactcttcg aaatttgtca
    14161 acactcaggt catctaaatt taatttaaga gaggaaacaa cattatgtta aaaatgaatc
    14221 ttgctaactt gcaacttttc gcccacaaaa aaggtggagg ttctacatca aacggacgtg
    14281 actcacaagc taaacgcctt ggtgctaaag ctgctgacgg tcaaactgtt tcaggtggat
    14341 caatccttta ccgtcaacgt ggaactcata tctacccagg tgtaaacgta ggccgtggtg
    14401 gagatgacac actttttgct aaagttgaag gtgttgtacg tttcgaacgt aaaggacgcg
    14461 ataaaaaaca agtttctgtt tacccagtag ctaaataatt gtttaatatc gcattatata
    14521 aggctttcca ggtgtctgga aagccgattt ttttattttg ctactcattt gctacccata
    14581 ttctaaaagc cgatgtagga agagagcttg tcagcagttt tatcttttga ggatttagta
    14641 acatgagcgt agatattcat ggtagtttgg atagtttcac aaccaagtgt attggatttt
    14701 cttctatcct actaaagatt gtagttgctt atttagagca atagttctaa ttgtaaaaag
    14761 tcagcataat aaaacaatat cataagatgt tgttataacg ggctttatgg tataattaag
    14821 gatactcatt ttaggaagga aagcaatgaa tattcaacaa ttacgctatg tggtagccat
    14881 cgctaataat ggaacttttc gagaagctgc ctctaaattg tttgtcagtc agcctagctt
    14941 atcagtttct atcaaagatt tagaggcgga attagggttt caaattttta atcggactac
    15001 ttcaggaaca gtcttgacaa gtcaaggact agttttttat gagaaagctt tagaagtagt
    15061 caaatctttt gattcttttg aaaaaacctt ttctcaagct gatctggatc aaaatgaatt
    15121 ttctattgct agccaacatt atgacttttt gccacctctt attacagctt tttcgcaaca
    15181 atacgatggt catcgtgtct ttcgtatttt tgaatcaaca actattcaaa ttttagatga
    15241 agttgctcaa ggaaacagtg aaattggtat tatttacttg aatgtagaca atcaaaaagg
    15301 tctctttcag cggatggata agctgggctt ggaatatgtt tctctaattc ctttcactac
    15361 tcatatttat ctttcaaaaa cgcatccatt ggctaatcgc gaagcgcttt atttgaacga
    15421 tattcaagga ttacctgcgg taaggtttac ccaagaaagg gacgagtatt tgtattattc
    15481 tgaaaatttt gtggatacta gtgaatgccc tcgtatttat aatgtgtcag atagggcaac
    15541 cttgaacggt attttagaga gaaccaatgc ctttgcgaca ggatcaggtt ttctcgatca
    15601 tcggagtgtt aatgggatta aagtgatacc tctagctgat catattgaca atcaaatgat
    15661 ttatgtcaaa cgaaaagata aaaacctttc tgttgctggg gccacttttg tgactatttt
    15721 aaaagactat tttgataaaa gaaggaaggc cttaacatga aaaaacgatt gtttgtgcct
    15781 agcttgatcc tccttgtagc tttggatcaa cttagtaaat tttggattgt ttctcatata
    15841 gcgcttggag aagtgaaacc ctttatccca ggtatcgtca gcttgactta cttgcaaaac
    15901 aatggggctg ccttttccat attgcaggac cagcaatggt tctttgttgt cataacggtt
    15961 ttagttatcg gttatgctat ttattacctt gctactcatc cccatttaaa tatctggaag
    16021 caattagctc tcttgcttat tatttctggt ggaatcggga attttattga tcgtttgcgt
    16081 ttagcttacg tgattgatat gattcattta gactttatgg attttgccat ttttaatgtg
    16141 gcagattcat accttaccgt tggtgtcata ttattagtga tatgtttatg gaaagaagag
    16201 gattatggaa attaatgtga taacatcggg gcaacgcttg gataaggcac tagctgattt
    16261 aagtcccctg tcacgtggtc aagccaatga ccaaattaag caaggccttg ttttagttaa
    16321 tggtcagcaa aaaaaggcta aatatacggt tcaagcagga gatgtgattt gttttgaact
    16381 ccctaaagaa gaagtcttag agtaccaagc tcagaatatt cccttggaca ttatctatga
    16441 agatgatgct ctcgccatta ttaacaagcc acagggaatg gtagttcacc cttcggcggg
    16501 acacccttca ggaacaatgg ttaatgcctt gatgtatcat atcaaggatt tgtcctcaat
    16561 caatggtgtg gttcgtccag gaattgttca tcggattgat aaggacacct caggtctctt
    16621 aatggtagct aaaacagatg cagctcatca agccttggca gaagaattaa aggctaaaaa
    16681 atctctcaga aaatacctcg ccattgtcca tggaaaccta ccgaatgatc gcgggatgat
    16741 tgaagctcct ataggtcgta gcgaaaagga ccgtaaaaaa caggctgtta cagcaaaagg
    16801 caaagaagca gtgacacgtt ttacagtgct agaacgtttt ggcgattaca gtctagtgga
    16861 attacaactg gaaactggtc gaacgcacca aattcgtgtt catatggcct atattggtca
    16921 tcctgttgct ggggaccctt tatatggacc acgtaagaca ctatcaggtc atggtcaatt
    16981 tcttcatgca aaaacattgg gattaacgca tcctatgaca ggaaaagaaa tgatatttac
    17041 tgttgaagct cccgaaattt ttcaaaaggt gttaaagctg ctaagaaaaa aataaacagc
    17101 gaggagtagc cattattttt agtcttatat ctttgtgtaa agtttttaac attataaaaa
    17161 atactaaaaa gcatttacga taagccagga aatatgagaa gtcttttatg ttattgggat
    17221 atgcaacata tctgttagag atctttattt aaactcctta aagaaaagag atattccaaa
    17281 tagatgctag gtattgtctt ttttacttgt ttttcttttc tttttttgct atactgattg
    17341 aaataaaata ttcctttaaa acagtcctgt gaggctgtca aggagacgga ttaaaaacat
    17401 gcactatgat acttaattgt gctatatttt gctgaatctc cttgtttcca aggagatctt
    17461 tttatttgaa tttttagagg aggtttcaac atgaaaacta aggaaattgt tgatgacgtg
    17521 accatgaaac gcgccattac ccgtattact tatgaaatta tcgaacgaaa caaacaattg
    17581 gacaatgtgg ttttggcagg catcaaaacg cgaggtgttt ttctagctcg tcgcattcaa
    17641 gaaagactgc atcaattaga agggttggat ttaccaattg gtgagttaga caccaagcct
    17701 tttagagatg acatgagagt tgaggaagac acaactctca tgtcagtaga tattacaggc
    17761 aaggatgtga ttttgattga tgatgtgctt tatactggtc gtaccatccg cgcagccatc
    17821 gataacttag tgagtttagg tcgaccagcc cgtgttagtc tagctgtttt ggtggatcgt
    17881 ggccatcggg aattaccgat tcgcgcggat tacgttggga aaaatattcc aacaagcagt
    17941 gtagaagaaa ttgttgttga ggttgtcgaa gtcgatggcc gtgatcgtgt tagcattatt
    18001 gacccaacat aagaaagagg ttttactgtg aaagatgtca gttatgatgt ggaagaagtg
    18061 ccaaaggcag gtatgttagt tggtttgtcc tttcagcact tatttgctat gtttggtgcg
    18121 actgttctgg ttcccattct agttggaatt gacccatcag ttgctttgtt atctagtggt
    18181 ttaggaaccc ttgcccactt atcagtgacc aaatttaaaa ttccagccta catgggctca
    18241 agttttgctt atatagcagc tatgcagtta ctgatgaaga caaatggtat tggtgctgta
    18301 gctcaagggg ctatgacagg aggtctcgtt tacctgattg tagctttgat tgttaaagct
    18361 attggcaatg attggattga taacatctta ccaccgattg tggttggtcc gattgttatg
    18421 gtcattggtc taagcctagc ttctacagct gttaatgatg tcatgctaaa aaatgggaac
    18481 tataatctga cttatcttgt tattgggtta gtcaccttat tatcagttat ttttttcaat
    18541 atttatggta aaggaattgt tgctattgta ccaattttat tggggctatt agttggttat
    18601 gttgtagccc ttttagtggg tgttttcacc ggtcaagaaa ttgttgattt taccaatgtg
    18661 gctcaggcca aatggtttag tatcccatca gtggaaattc ctttcttaac ctacggggtt
    18721 aaattctacc caagtgccat tttaactatg gcacccattg cctttgttac aatgacagaa
    18781 cattttggac acattatggt cttaaatagt ttgacaaaaa gagattattt caaggatcca
    18841 ggacttgaaa agactttaac tggtgatggt tttgcgcaaa tcattgccgg cttcttaggg
    18901 gcacctccgg tcacttctta tggtgaaaac atcggtgtaa tggctttgaa taaaatatta
    18961 tcggtctatg ttattgcagg tgccgcagtg attgccgctc tcctcagttt tatcggtaag
    19021 gtatcagcct taattcaatc tattccaaca ccagttattg gaggtatatc agttgccttg
    19081 tttggtgtaa tagcttctag cggtttgaaa atcttgattg aatccaaagt tgatatggat
    19141 aataagaaaa acttattgat tgccagtgtt attttggtct ctgggattgg aggattgatg
    19201 cttcaagtaa atggtcttca aatttcaggt gtcgctttct caacacttct tggcatcatc
    19261 ttatatcagg tacttcctga aaaataggaa gaattgttgt tagaccactt acatagtcat
    19321 cagtcgttaa tgataaaggg gataatcatg tcagttgtaa ataatcgcgt tgcacttacc
    19381 aatttagttt caatggaagc attaaccacc gaagaagttt taggtcttat caaccgtggt
    19441 tcagaatata aggctggtaa ggttgttatt tcggatcatc aaaaggatct tgttgccaat
    19501 ttattctttg aaaactccac ccgaacccat aagtcttttg aagtggctga gaagaaactc
    19561 ggcttgacag ttcttgattt caatgctgat gcaagtgcgg ttaacaaggg agaaagtttg
    19621 tatgatactg tgttaaccat gagtgcactt ggaacagaca tctgtgtgat tcgtcaccca
    19681 gaagatgatt attacaagga attagtagaa agtccaacta ttacagcttc cattgtcaat
    19741 ggaggagatg gttctggaca acacccgagt caatgtttac ttgacttatt aaccatctat
    19801 gaagaatttg gacgctttga aggcttaaag attgcgatcg ctggtgactt aactcactct
    19861 agggtggcaa agtccaacat gcaaatcctc aaaagattag gagcagagct ttatttctat
    19921 ggacctgaag aatggtattc agaagccttt aatgcttacg gcacttatat tgctattgac
    19981 cagattatta aggaattgga tgttcttatg ttgctgcgtg tacagcacga acgtcatgac
    20041 ggccatcaga gtttttcaaa agaaggttac catcaagcgt ttggattgac acaggaacgt
    20101 taccaacaat taaaagattc tgctattatt atgcatccag ctccagttaa tcgggatgtg
    20161 gaaattgcag atagtttggt ggaagctcct aaagcgagaa ttgtatctca gatggctaat
    20221 ggtgtctttg ttcgcatggc tattattgaa gccattttga atggtagaaa taaaaactca
    20281 tgatgaaaga ttaaagcatg tttagaaggt aggaaaaggt aggaaaatga caaaacgatt
    20341 acttatttta gaagacggca ctatttttga aggagaaccc tttggtgctg atattgatgt
    20401 gactggtgaa attgtcttta atacaggaat gacaggctac caagaatcca tcactgacca
    20461 atcctacaat gggcaaattt taacctttac ctatcctttg attggaaatt atgggattaa
    20521 tcgagatgac tatgagtcca tttcacccac ctgtaaaggg gttgttgtgt ctgaagtcag
    20581 tcggttggca agtaattggc gcaagcaaat gacgctagat gcgttcttga aaataaaagg
    20641 gattccaggg atttcgggaa ttgatacgag agctttgacc aaaattattc ggcaacacgg
    20701 taccatgaaa gctacgatgg cagatgatgg agatagtatc cagcatttaa aagatcaact
    20761 gcgtgcaaca gtcttaccga ctaacaccat tgaacaagtg tcaactaaaa cagcttatcc
    20821 tgcaccaggg atcgggaaaa atattgtatt ggttgatttt ggtttaaaac attctatttt
    20881 aagagaattt tctaaaagac aatgtaatat caccgttgtc cctttcaaca tcactgcaga
    20941 agaagtgctc caactaaatc cggatggttt gatgctatct aatggcccag gaaacccaga
    21001 agatttgcca gaggctttag acatgattcg tggggtacaa ggtaagattc ctatttttgg
    21061 tatttgtatg ggacatcaac tctttagtct agcaaatggt gccaagactt gtaaaatgac
    21121 ctttggtcat cgtggcttta accatgccgt tagagaaatt gcaacgggaa gaattgattt
    21181 taccagtcaa aaccatggtt atgccgttga acgtagtagt ctacctgata ctttaatggt
    21241 tacgcatgaa gacattaacg ataagacggt cgaaggagtg aaacatagag attttccagc
    21301 tttttcagtc caatttcacc ctgatgcggc tccaggacct catgatgcca gctacttatt
    21361 tgacgaattt ttggaaatga ttgattcttg gagatgtacg agtaaatagt aaatcagttg
    21421 caatttcacg actatatcac ctcttgttac tctatttatt aacatttaca gttgatttag
    21481 taccctatca aaaatattat ttaatgttgc tctgtgaggc aacaaataga gaaaggaagg
    21541 caaggagaac acaagtaaat aatttagtaa aaagttaggt tttcaaagag ataaagctct
    21601 tattgagaag tgctgacttt accgcttctt gtggtattct tggtatcatt aattatgcca
    21661 aaacgaaaag atattcaaaa aatcatggtt atcgggtctg gcccgattat tattggacaa
    21721 gctgctgaat ttgattatgc agggactcag gcctgtttgg ctctaaaaga agaaggctat
    21781 aaggtcatac ttgttaattc aaatcctgca acgattatga cagataaaga aatcgctgat
    21841 aaggtatata ttgagccttt gactcttgaa tttgttaatc gtatcattcg aaaagaaagg
    21901 ccagatgcca tactgccaac cttaggtggt caaacgggcc tcaatatggc aatggcatta
    21961 tctaaagctg gtattcttga tgatttagag attgaattgt taggtactaa gttatctgcg
    22021 attgatcagg cagaagacag agaccttttc aaacaattaa tgcaagaact agaccaaccc
    22081 attccagaat ctacaattgt taaaacagtt gatgaagctg ttacatttgc tagagatatc
    22141 ggttatccag tcattgtgcg cccagctttt actcttggtg gaactggtgg aggaatatgt
    22201 agtagtgaag aagaactttg tgaaattact gaaaacggcc taaagttatc accggtcaca
    22261 cagtgtttga ttgaacgctc aattgctggc ttcaaagaaa ttgaatacga agtaatgcga
    22321 gatagtgctg ataacgcgct ggttgtttgt aatatggaaa actttgatcc cgtagggatt
    22381 cacacaggag attctattgt atttgcacca acacagaccc tttctgatat tgaaaatcaa
    22441 atgttacgtg atgctagttt aaaaataatt cgagctctga aaattgaagg tggctgtaac
    22501 gtccagttag cactagatcc ttatagtttc aaatattatg ttattgaagt aaatcctaga
    22561 gtgtctcgtt cctctgccct tgcttcaaaa gcaacaggtt atcccattgc caaattggct
    22621 gcaaagattg ctgttggcct aacacttgat gaaatgatta accctatcac aggcactact
    22681 tacgctatgt ttgaacctac ccttgattac gttgttgcta aaattccgcg ttttccgttt
    22741 gataaatttg aacatggtga acgccaactg ggaactcaaa tgaaagcaac aggtgaagtc
    22801 atggctattg gccgtaattt ggaagagtcc ttactaaaag cctgtcgttc tttagaaatt
    22861 ggtgtttgcc ataatgagat gacaagttta agtaacatta gtgatgaaga gttagtgact
    22921 aaagtgatta aagctcaaga tgatcgactt ttttacttgt cagaagcaat acgacgaggt
    22981 tatagtatcg aagaacttga gagcttgacc aagattgatt tatttttctt ggataaatta
    23041 cttcatattg ttgaaataga gcaagatcta caaatgcatg ttgagcattt ggaaagcctc
    23101 aaaaaagcaa agcgttatgg attttcagat caaaaaattg cagaaatttg gcaaaaggat
    23161 gaaagtgata tcagagcgat gagacattct catagcctgt atcctgtcta taaaatggta
    23221 gatacttgtg cagctgaatt tgatgctaaa accccttatt tttattcaac atatgagttg
    23281 gaaaatgaat ctgttcagtc gaataaagaa tcaattttag ttttaggttc aggccctatt
    23341 cgtattggtc aaggggttga atttgactac gcaacggttc attctgttaa agccatccaa
    23401 aaagctggct atgaagccat tatcatgaat tcaaatccgg agactgtatc tacagatttt
    23461 tcggtatcag ataaattata ttttgaaccg ttaacctttg aagacgtcat gaatgtgata
    23521 gatttagagc agcctaaggg agtaatagtt cagtttggag gacaaactgc tattaactta
    23581 gcacaagcac tttctgaggc gggtgttaca atattaggaa cacaagtaga ggatttggat
    23641 agggctgaag acagagattt atttgaaaag gcgttgaaag agcttggaat cccacaacca
    23701 caaggtcaaa cggcaactaa tgaagaagaa gctttagagg cagctaaaaa aattggtttt
    23761 ccagtcttag ttagaccttc ttacgtactt ggtggccggg ctatggaaat tgttgaaaac
    23821 aaagaagatc ttagagaata tataagaaca gcggttaaag caagtcctga acatcctatc
    23881 ttagtggact cttatatttt cggtaaggag tgtgaagtgg atgccatttc agatggaaaa
    23941 tcagtcttaa ttcctggtat tatggagcac atcgaaagag caggtgttca ttcaggagat
    24001 tcaatggcag tttatccgcc acagcaatta tctaagcaaa ttcaagaaac aatagctgag
    24061 tatactaaac gtttagccat tgggttaaat tgtattggta tgatgaatgt tcaatttgtt
    24121 attaaaaatg aacaagtcta tgttattgaa gtgaatccac gcgctagtcg taccgtacct
    24181 ttcttatcaa aagtaacagg tattccgatg gctcagattg ctactaagtt gattttaggt
    24241 caaacattaa aggatctagg atatgaagat ggtctttatc cccaaagtca actggtgcat
    24301 atcaaagcgc ctgtgttttc atttacaaag ttggcacagg ttgatagtct tttaggtcct
    24361 gaaatgaaat caactggaga agtaatgggt tcggatacta gtcttgaaaa agcactttat
    24421 aaagcgtttg aagccaataa ttctcattta tcagaatttg gtcaaattgt ctttactata
    24481 gcagatgata gtaaggcaga agctctaagt ctagcaagac gatttaaggc gattggctat
    24541 caaattatgg ctactcaagg tacagcagct tactttgctg agcaaggctt aagcgcgtgt
    24601 ttagttggaa aaattggtga tgctgccaat gacatcccga cactcgtgcg acatggtcac
    24661 gttcaggcaa ttgttaatac agttggaatt aaacgcacag ctgataaaga cggacagatg
    24721 attagaagtt cagctattga acaaggagtt cctttattta cagctttaga taccgcaaaa
    24781 gctatgttaa cggttttaga aagcagatgc tttaacatcg aagcgatata aaaattaaaa
    24841 aaatcatttt taagaaaact taaaaatgat ttttttagat tataatgaca aaagtttcag
    24901 taagctatta atttgtcata gcatataagt cattattttg tggcttgttt tcgactaagg
    24961 actaagaatt tcttgacaac aatataaaaa ggtcatatac ttgtcttata caaatagtac
    25021 aaaaagggga ggatagaaat gtctaaaaga ggaaaaatta aaataacaac gaaaacaaag
    25081 cttattacag ctagtgttat aacgctagta ttaattataa ctggagtagt cttgtggaaa
    25141 caacaacaaa atatgctaac agctgatatc gctaaagaac cttactctac tgttagtgta
    25201 actgaaggga gtattgcttc ttcgacttta ctatcaggta ctgtaaaggc tttatcagag
    25261 gaatatattt attttgatgc taataaagga aatgatgcaa ctgttacagt taaagtaggt
    25321 gatcaggtaa cgcagggcca gcaattagtt caatataata caacaacagc tcagtcagct
    25381 tatgatactg ctgttaggag tcttaacaag attggccgac aaattaatca tcttaaaaca
    25441 tacggagttc ctgctgttag tacagaaact aataaagatg aagctaccgg tgaagagacg
    25501 acaacaacag ttcaaccatc agctcagcaa aatgctaatt ataaacagca gctgcaagat
    25561 ttaaatgatg cttatgcaga tgcacaagca gaagtaaata aagcgcagat agcgttaaat
    25621 gatacagtag ttatcagtag tgtctctgga actgttgtgg aagtaaataa tgatattgat
    25681 ccttcttcaa agaacagtca aacacttgtt cacgtagcaa ccgaaggaca gcttcaggtg
    25741 aaaggaacat tgacagagta tgatttagca aacgttaagg ttggtcaatc tgtaaaaatt
    25801 aagtctaaag tttattctaa tcaagaatgg actggaaaaa tatcatatgt ttcaaactat
    25861 ccaactgagt ctaatgcagg ttcaacaacg ccagcaggta gcactggagc gggaagttct
    25921 acaggagctg cctatgatta caagattgat attataagtc ctctcaacca gcttaaacaa
    25981 ggcttcactg tttctgttga ggttgttaat gaagcaaaac aggccttagt tcctttaacg
    26041 gctgttatta agaaagataa aaaacactat gtttggactt atgatgatgc tactggcaaa
    26101 gccaaaaaag tagaggtgac acttggaaac gcagatgcac aacaacaaga aattcataaa
    26161 ggagtaactg ttggtgacat tgttattgcc aatccagata aaaatatcaa accggataaa
    26221 aaactagaag gggttatttc aataggtacc aacacaaaac cggaaaaaga ttctcaatca
    26281 aagaataaaa aatcaggggt ggataaatag tgtcgcatga aaaaaaacaa ttaatgcaat
    26341 tatcaaatat tgtgaagagc tatcaaaatg gggatcaagt tcttaaagtt ttgaaaggta
    26401 ttaatttaac agtatatgag ggtgaatttt tagctattat gggtccgtct ggctcgggaa
    26461 aatcaacact aatgaatatt attggtttat tagatcggcc aacatccgga gattacacat
    26521 tacataatac taaaatagaa atctttaatg atcgtgaatt agcaaaagta cgaaatgatg
    26581 aaatcggctt tgtctttcaa caattctttc tgttagctaa attaactgca ttacaaaatg
    26641 ttgagttgcc tcttatttat gctggtgtaa acgtctcaaa aagacgtgaa caggctaagc
    26701 aatttcttga aaaagtagga cttggacgac gtatcaaaca tctaccgtca gaactgtcag
    26761 gaggtcaaaa gcaaagggtg gctatcgcac gagctttagt aaatgaccca tctattattt
    26821 tagcggatga accaacaggt gcactagata ctaaaacagg tcagcaaatt atggaactct
    26881 tgacagagtt aaacaaagaa ggtaaaacaa ttattatggt tactcatgaa ccagaaattg
    26941 ctgattttgc aactcggaaa attattattc gtgatggtga tatcacaacg gatactacag
    27001 ctagtgttgt tattgactag gaggaaaaat aatggaaaat tggaaattcg ctcttagctc
    27061 aatttggggg cataagatgc gctcaatcct gacaatgttg ggaattatca tcggtgtagc
    27121 agcagttgtg attattatgg ggttgggaaa tgctatgaaa aatagtgtaa caagcacatt
    27181 ttctagcaag caaaaagata ttcaactcta ttttcaagaa aaaggagaag aagaagacct
    27241 gtatgccgga ttgcacacgc atgaaaataa tcacgaagtg aagccagagt ggttagaaca
    27301 aattgttaaa gatatcgatg gtattgattc ttattacttt accaattctg ctacttctac
    27361 tatttcgtat gaaaaaaaga aagtagacaa tgcttcgatc ataggggtaa gtaaagatta
    27421 ttttaatata aaaaactatg atatcgtagc tggtcgtaca ctaacagata atgattattc
    27481 taatttttcg cgtatcattc ttttagatac agtattagcc gatgacctat ttggcgaagg
    27541 taattataag tcagctttaa ataaagtggt aagtttatct gataaagatt atttagttat
    27601 tggtgtttat aaaactgatc agacgccagt ttcttttgat ggattatcag gcggcgctgt
    27661 catggcaaat actcaggtag cttcagagtt tggcaccaaa gaaataggat ctatctacat
    27721 tcatgtgaac gatattcaaa acagtatgaa cttaggaaat caagcagctg atatgctaac
    27781 caacatatcg catattaaag atggacagta cgctgttcct gataatagca aaatcgttga
    27841 agaaatcaat agtcagttca gtatcatgac aacagtcata ggttcaattg cagcgatctc
    27901 tcttttagtg ggaggaattg gtgttatgaa tattatgttg gtatctgtca cagagcgaac
    27961 tagggaaatt ggtttacgta aagcacttgg tgcaacacgc ctgaaaattt tatcacaatt
    28021 tttgattgaa tccgttgttc taacagttct tggaggcttg ataggattat tattagctca
    28081 attaagtgta ggggctttag gaaatgcgat gacattaaaa ggagcttgta tttctcttga
    28141 tgtggcctta atagcagttt tattttctgc ctcaataggt gtcttttttg gaatgttgcc
    28201 agctaataaa gctagtaagt tagatccaat tgaggcatta cgttatgaat agaatagttc
    28261 gtatcaatta atctatagac gctgactagt ttaacgtctg attatatcta ttttttgtat
    28321 tagcacagta gttatatcat tgaagtgtta gtgcattttt tgaggtgata atatctagca
    28381 aagctatcat tggtatgatg atgtggatag cgtataagtg atacatctct tatttctagc
    28441 tgaacttcgg ttcggctagg aagttgtcag gcaatgagtt gtttaaaata aaggagatta
    28501 gttcaatgac atttttatct gatttgatat cattaatgac aaaaatcaga ttatcctggg
    28561 taataaaggc gggtattttt caattattat ttgtaacgat tgctaatatt gtcttatcag
    28621 aatttttcta ttttatatta gacgttactg gtcaatatca tttagataaa gacaatgttg
    28681 tgactttttt aaaaaatcct atagcacttg ctttattagg tgcctattta tttttattag
    28741 ctgcttttat tcaccttgag ttttttgctc tatatcgaat tattgcggat caagaaatta
    28801 gtttctatct ttttagaaaa cagttttctt attacctaag ggggctttgg aaaacatttt
    28861 ctggttacca attattactt tttttgcttt atatcctact gactattcca gtcttacata
    28921 ttggtttatc ttctgtgatt actcaaaagc tttatcttcc agaatttatt gttggggaat
    28981 tatcaaagat aactagcaca aagtacttgc tttatggcag tcttattctt gtgttttacc
    29041 ttaacctaag attagtatat tttttaccat tgatagcaat caaccatcgt acggttgctc
    29101 aagcatggag agagagttgg caaaagacta aaaagaaaca tgtattgtta tggatgaaac
    29161 tttttgcaat caatggtctt acgcttgtag tcttatcgct agctatttcc atgattctta
    29221 tttttgttga tatgtttaat cctaagggga ataatattat tgttcagctg ggagctttga
    29281 cctttacatg ggagctcatt ttttttacta ctattttttt taaactctgt tcagcaatga
    29341 ttttaaaaga ggcaattgaa ccacaaaagc aatatgatga gccaagaaga agtaataagg
    29401 catatgttgt aatctttatc gtggtgacag taggttttgc ttatcaatct cttgaacgtt
    29461 taactttttt tgacatatct cactctaaga cagttatcgc gcatagagga cttgtatcag
    29521 caggtgtaga aaattctctg gaagcccttg aaggtgctaa gaaagcagga agtgattatg
    29581 tagaactgga tctaatcttg actaaggata atcactttgt ggtgtctcat gataatcgat
    29641 tgaagcgttt agctggagta aataagacga ttcgcaactt aaccttaaaa gaagttgaac
    29701 atctaacgag tcatcaagga catttttcag ggcgttttgt ttcttttgac actttttatc
    29761 aaaaggctaa gaagttgaat atgccattac ttattgaact caagccaatt ggtacagaac
    29821 ctggaaatta tgtcgatttg tttttagaaa cttatcatcg acttggtata agcaaagata
    29881 ataaagtcat gtctttagat ttagaagtaa tagaagctat caagaaaaaa aatccatcaa
    29941 ttacgactgg ttatatcata ccaattcaat ttggcttttt tggagatgaa tttgttgatt
    30001 tctatgtcat tgaagacttt tcttatcggt cttatttgtc gtcccaagct ttttggaata
    30061 ataaagaaat ttacgtttgg actattaatg atcccaagcg catagagcat tatctcctaa
    30121 agcctattca gggaattatt acagatcaac cagctttaac taatcaattg attaaagact
    30181 taaaacaaga taattcttat tttagtcgat tagtcagaat tattagtagt ctttattaaa
    30241 ggtttaaaga aagtgtcaag aaaaaaactt gacactttct ttaaactgag ttatactgtt
    30301 taacatagga atttagcgta gctgtatttc ttatacatta ctaaaagaaa agagactatt
    30361 taaaaatggc agtaaaaatc cgtttaactc gtatgggttc taagaaaaaa cctttctacc
    30421 gtattaatgt tgcagattca cgtgcaccac gtgatggtcg ttttatcgaa acagttggaa
    30481 catacaaccc attagtggct gaaaatcaaa ttactattaa agaggatcgt gttcttgagt
    30541 ggttatctaa aggagcgcag ccttctgata ccgttcgtaa catcttgtct aaagctggtg
    30601 ttatggctaa gttccacgac caaaaattct ctaaataata atagcctatg gataccattg
    30661 aaaatcttat tatcgctatt gtgaaacctt tgatttcaca accagataat cttaccatta
    30721 aaattgaaga tactcctgac tttttagagt atcatcttga cttggatgct caagacatcg
    30781 gtcgtgttat cggcaaaaaa ggtcgaacta ttactgcgat aagatcgatt gtctactcgg
    30841 ttccaacact aggaaaaaaa gttcgcttag ttattgatga gaaataatca ctaacttgag
    30901 atggattgaa aagcttgttg actttaagtc aacaagcttt ttgaatagca aaaatcttaa
    30961 tatttctgaa atgaaaagat tagatttttc tgtctttaac taaaaagaag ttaaagaatg
    31021 gcttagctga ttgcctttat aagagattat actggttttt gatagctgct gtcatgtaaa
    31081 atagctacaa ttcatcttac gagattgacc ttagcattgc cagtgcagtc tttattttcc
    31141 aacctgctgt ttgttgtatg tttatagttt cctaaaaaat gctctctcag ttttttgggg
    31201 gacattccta aaattaagta tacttaattt taggaatgtt tatattcttt acattctgat
    31261 gaaaatacaa attatcctaa catgatgtat tgaaaggaga aatagtttat gttagtatac
    31321 tgattaagtg aagctgtaat gaggcttata cgatcaaaaa agttagagta actttataaa
    31381 acagtggtgt tgaagcaagt ttagcttctt ctcagaaata gattatctat aaaaaatccc
    31441 aaaagtagtt tgtttccagt taatgaactt cttttgggaa ggcttttttg ctgatcgcca
    31501 cttcacttgt atatcgggaa cattcacgct aagatgtata agttgaatcg tttgtctatg
    31561 gcttgatgaa aattaatcaa aagataatgt tcaactctat aattagtaca agcaaaatga
    31621 gataacttat tcattagtaa gcataagata taacaagaga aattacctta aaacaggaag
    31681 tactagagta tttaaaataa gtgatagact tggatattat taggtcgact agtgtccttt
    31741 tcaataattt aatatcgtta ttattagtat cagccaatca aatgtggata agttggcttt
    31801 tagaaaggtt ttaccacaat gaagaaacat cttaaaacag ttgccttgac cctcactaca
    31861 gtatcggtag tcacccacaa tcaggaagtt tttagtttag tcaaagagcc gattcttaaa
    31921 caaactcaag cttcttcatc gatttctggc gctgactacg cagaaagtag cggtaaaagc
    31981 aagttaaaga ttaatgaaac ttctggccct gttgatgata cagtcactga cttattttcg
    32041 gataaacgta ctactcctga aaaaataaaa gataatcttg ctaaaggtcc gagagaacaa
    32101 gagttaaagg cagtaacaga gaatacagaa tcagaaaagc agatcaattc tggatctcaa
    32161 ctagaacaat caaaagagtc tctttcttta aataaaagag tgccatcaac gtctaattgg
    32221 gagatttgtg attttattac taaggggaat acccttgttg gtctttcaaa atcaggtgtt
    32281 gaaaagttat ctcaaactga tcatctcgta ttgcctagtc aagcagcaga tggaactcaa
    32341 ttgatacaag tagctagctt tgcttttact ccagataaaa agacggcaat tgcagaatat
    32401 accagtaggg ctggagaaaa tggggaaata agccaactag atgtggatgg aaaagaaatt
    32461 attaacgaag gtgaggtttt taattcttat ctactaaaga aggtaacaat cccaactggt
    32521 tataaacata ttggtcaaga tgcttttgtg gacaataaga atattgctga ggttaatctt
    32581 cctgaaagcc tcgagactat ttctgactat gcttttgctc acctagcttt gaaacagatc
    32641 gatttgccag ataatttaaa agcgattgga gaattagctt tttttgataa tcaaattaca
    32701 ggtaaacttt ctttgccacg tcagttaatg cgattagcag aacgtgcttt taaatcaaac
    32761 catatcaaaa caattgagtt tagaggaaat agtctaaaag tgatagggga agctagtttt
    32821 caagataatg atctgagtca actaatgcta cctgacggtc ttgaaaaaat agaatcagaa
    32881 gcttttacag gaaatccagg agatgatcac tacaataacc gtgttgtttt gtggacaaaa
    32941 tctggaaaaa atccttatgg tcttgctact gaaaatacct atgttaatcc tgataagtca
    33001 ctatggcagg aaagtcctga gattgattat actaaatggt tagaggaaga ttttacctat
    33061 caaaaaaata gtgttacagg tttttcaaat aaaggcttac aaaaagtaaa acgtaataaa
    33121 aacttagaaa ttccaaaaca gcacaatggt gttactatta ctgaaattgg tgataatgct
    33181 tttcgcaatg ttgattttca aaataaaact ttacgtaaat atgatttgga agaagtaaag
    33241 cttccctcaa ctattcggaa aataggtgct tttgcttttc aatctaataa cttgaaatct
    33301 tttgaagcaa gtgacgattt agaagagatt aaagagggag cctttatgaa taatcgtatt
    33361 gaaaccttgg aattaaaaga taaattagtt actattggtg atgcggcttt ccatattaat
    33421 catatttatg ccattgttct tccagaatct gtacaagaaa tagggcgttc agcatttcgg
    33481 caaaatggtg caaataatct tatttttatg ggaagtaagg ttaagacctt aggtgagatg
    33541 gcatttttat caaatagact tgaacatctg gatctttctg agcaaaaaca gttaacagag
    33601 attcctgttc aagccttttc agacaatgcc ttgaaagaag tattattacc agcatcactg
    33661 aaaacgattc gagaagaagc cttcaaaaag aatcatttaa aacaactgga agtggcatct
    33721 gccttgtccc atattgcttt taatgcttta gatgataatg atggtgatga acaatttgac
    33781 aataaagtgg ttgttaaaac gcatcataat tcctacgcac tagcagatgg tgagcatttt
    33841 atcgttgatc cagataagtt atcttctaca atggtagacc ttgaaaagat tttaaaacta
    33901 atcgaaggtt tagattattc tacattacgt cagactactc aaactcagtt tagagacatg
    33961 actactgcag gtaaagcgtt gttgtcaaaa tctaacctcc gacaaggaga aaaacaaaaa
    34021 ttccttcaag aagcacaatt tttccttggc cgcgttgatt tggatgaagc catagctaaa
    34081 gctgagaagg ctttagtgac caagaaggca acaaagaatg gtcagttgct tgaaaggagt
    34141 attaacaaag cggtattagc ttataataat agcgctatta aaaaagctaa tgttaagcgc
    34201 ttggaaaaag agttagactt gttaacagga ttagttgagg gaaaaggatc attagcgcaa
    34261 gctacaatgg tacaaggagt ttatttatta aagacgcctt tgccattgcc agaatattat
    34321 atcggattga acgtttattt tgacaagtct ggaaaattga tttatgcact tgatatgagt
    34381 gatactattg gcgagggaca aaaagacgct tatggtaatc ctatattaaa tgttgacgag
    34441 gataatgaag gttatcatgc cttggcagtt gccactttag ctgattatga ggggctcgac
    34501 atcaaaacaa ttttaaatag taagcttatt caattaacat ctattcgtca ggtaccgact
    34561 gcagtctatc atagagccgg tattttccaa gctatccaaa atgcagcggc agaagcagaa
    34621 cagttattgc ctaaaccagg tacgcactct gagaagtcaa gctcaagtga atctgctaac
    34681 tctaaagata gaggattgca atcacaccca aaaacgaata gaggacgaca ctctgcaata
    34741 ttgcctagga cagggtcaaa aggcagcttt gtctatggaa tcttaggtta cactagcgtt
    34801 gctttactgt cactaatagc tgctataaaa aagaaaaaat attaaattga tttaaggaga
    34861 aaaaatgata acacaagaaa tgaaagatct tattaataac cagttagcaa tggttgcgac
    34921 ggttgatgcc aaaggtcaac ccaatattgg tccaaaacgt tctatgcgtc tctgggatga
    34981 taaaacattt atttataatg aaaatacaga tggtcaaact cgtattaaca ttgaagataa
    35041 tgggaaaatt gaaattgcct ttgttgatcg tgagcgcctt ttaggttaca ggtttgtagg
    35101 aactgctgaa attcaaacag aaggtgctta ttacgaagca gcgaaaaaat gggcacaagg
    35161 acgcatgggg gtaccaaaag cagttggtat tattcatgtc gagcgtattt ttaatttaca
    35221 atctggtgct aatgcaggta aagaaataaa cagtgaaagt aactaaaatt aactgtaaca
    35281 gtatttagga cccttatttt aaacgctaaa aaacaagcat actctttttt acagcatagt
    35341 gactatgttg taaaaagggg tatgcttatt aggtgctctt aatatttcta gataactgca
    35401 tctaataagt ttttaataga cttatagcac attaatagac ttcaattagt tgactttaat
    35461 actagaaaga gaagaacagt gatgttggtg ttcgtttaaa gaagtatcga tttccacagt
    35521 gactgagttt atattgtacc tttgacaaat cagtctaata gattttttgc aatgtttttc
    35581 agtggtagat tctctcaagc agcaatgtat agttgctcta tgatcaatac catccatcga
    35641 ccaaacatta agctgattaa cagacactat atgaggaagt tggctgagtt catggtgcaa
    35701 agcgcaatag tctatcgaat caggaacacc atctaaaaaa atgttagcag ttgctactaa
    35761 ctttggaaga gctttagata atataaaaga agcaatggca attgataata aaggatcaag
    35821 aatgtaccaa ggtttccatt ttaagatcag tgacaatatg ataatggcta accacccaag
    35881 gatatcttct aaaaagtgaa ggcttaatat ttcttcattt tttgtctggt tagagtgaat
    35941 gatgaagcta gcaaatccat tgattataat tgcaaaaata gctaaaacga acataccgtc
    36001 ataattaaca atagtaggat gccataattt tggtatcgtt tcaatcatta ctaataatga
    36061 cccgctaata agtattagat ttgttgttag tgctcctaaa aggctaaatc gcttatagcc
    36121 tagtgaaaaa tttggactct cttttttaac agcctttctt tctaagatag ctgagatacc
    36181 aatagcaatg gcatctccaa aatcgtggac agcatctgct aaaatagcac ccgaaaagaa
    36241 taatgttcca aaaataaatt caatgaggga aaaactaaga tttaatataa aaataatggt
    36301 gactttttta cttgctggca taattttctc cttttgttat actggtaata tgtatagtag
    36361 aattctttat tctattatct agaagttaaa atacaattac tataaccaaa aatgagcacc
    36421 tgttcaatag tgaacaacat ttagaaagtg tccgatatga caaaagacag acaaatcaaa
    36481 aaaacaaaaa cagctatcta tagtgctttt attgctttat tacaaaaaaa agaatattcg
    36541 aaaataactg ttcgagatat gattacactt gctaatgtag ggagatcaac cttttatgca
    36601 cattatgaaa gcaaagaaat gttactaaaa gaactctgtg aagaactttt tcatcatttg
    36661 tttaggcaaa aaagaaatgt gacttttgaa gactatttgg tacatatttt aaagcatttt
    36721 gaacaaaata aagacagcat tgcgacgttg ttactttcta atgatcccta ttttttatta
    36781 agatttaaaa acgaactaga acatgatgtt taccctaact tgcgctgcaa gtatatcgac
    36841 aaaacgacta ttccagaagt attcctgaaa caatttgttc tatctagttt tgtagaaacc
    36901 ttaaaatggt ggctccatca aaggcaaagg atgtctgcaa atgaactatt aaagtattat
    36961 ttagagctca taaaataatg actagtgagt catcttgcca aattcaattt tttaatacag
    37021 acgtatttta acaatttaac agagaaagac aaaactgtaa gtgcaaaata gactataacg
    37081 tgataaaata ataggtaatt tggttctgaa aaagaagtgt ctatcaaact ttagaatcaa
    37141 gagaggtcgc taaagtgacg tgagataaag agttaacgat ttaggagcta ccatggaata
    37201 ttttaatgtt ggaaaaattg tcaacacgca aggcctgcaa ggagagatgc gcgtgttgtc
    37261 tgtcagtgat tttgctgagg aacgctttaa aaaaggctca caattagctt tatttgatga
    37321 taaagatcgg tttgttcaag aagtgacaat tgttagtcac cgtaaacaaa agcattttga
    37381 tattatcaaa ttgaaagaca tgtatcatat taatgctatt gaaaagtaca agggatacac
    37441 tttaaaggtc tcaaaagata atcaagggga tttacaagaa ggagaatttt attaccatca
    37501 gattattggc atggctgttt atgaaaagga ccggttgatt ggctatgtca aggaaatctt
    37561 gcagccaggt gctaatgatg tttgggtagt gaaacgccaa ggaaaacgag acttgctctt
    37621 accatatatt cccccagtag ttcttaacgt agatgttcct aacaagcgcg tggatgttga
    37681 attgatggaa ggcttagacg atgaagattg atattttaac cctttttcct gaaatgtttg
    37741 cccctctaga gcattccatt gtaggcaagg caaaagaaaa aggtctgtta gacattcact
    37801 accataactt tcgagattat gctgaaaaag ctcgtcatgt ggatgacgaa ccctatggtg
    37861 ggggccaagg catgttattg agagcgcagc ccatttttga caccattgaa cagattgaag
    37921 ccaaaaaacc aaggattatt cttttagatc cagcaggtaa accctttact caggcttatg
    37981 ctgaagaatt agctcttgag gaagagttaa tttttatttg tggtcattat gaaggttatg
    38041 atgagcggat taagaccttg gtgacggatg aaatttcatt aggcgacttt gtattaacgg
    38101 gaggtgagtt ggcggccatg actatggtgg atgcgaccgt caggttaatt ccacaggtac
    38161 ttgggaaaga aagtagccat caggacgatt ctttttcatc aggactttta gaataccctc
    38221 aatacacaag accttatgat tatcgtggta tgacagttcc agatgttcta atgagtggtc
    38281 atcacgaacg tattcgcttg tggcgtctag aagaaagtct cagaaaaacc tatttgagaa
    38341 ggccagattt gttagagcgg tacgattttt ccgaggaaga gcgcaagcta ttggataaga
    38401 ttaaagaagc attgggtcaa ggagaagatt agtgaaagat aaagcatatg atattacgat
    38461 tattggtggt ggtccaatag gtttatttgc agccttttat gcaggtctta ggggcgtaac
    38521 agtaaagatt attgagagtt tgtcagaact tggtggacag cctgccattc tttatcctga
    38581 gaaaatgatt tatgatattc cagcttatcc atctttaaca ggtgctgagt tgacagaaaa
    38641 tttaataaaa caattaagcc gttttgaaga tcgtacaacc atttgtttaa aagaagaagt
    38701 attaaccttt gacaaggtta aaggtggttt ttcgattagg actaataagg cagagcattt
    38761 ttcaaaagcc attatcattg cttgtggaaa tggcgctttt gcacctagaa ctttagggtt
    38821 agaaagtgag gaaaactttg ctgatcataa ccttttttat aatgttcacc agttggacca
    38881 gtttgcggga caaaaagttg tgatttgtgg tggtggagat tcagcagttg attgggcttt
    38941 ggctttagaa gatattgctg agagtgtgac ggttgtgcac cgtcgtgatg ctttcagagc
    39001 acatgaacac agtgtggaat tattgaaagc atcaacggtc aacctcttaa caccttatgt
    39061 gccaaaagca ttgaaaggaa ttggaaacct ggctgaaaaa ttagttattc aaaaagtgaa
    39121 agaagatgaa gtgttagaac ttgaattgga cagtcttatt gttagttttg gtttttcaac
    39181 ttctaataag aatttgaaaa attggaatct cgactataag cgttcaagta ttactgtttc
    39241 accacttttt caaacaagtc aagaaggtat ttttgccatt ggtgatgcag ccgcttataa
    39301 tgggaaagtg gatttgattg ctactggttt tggcgaagca ccaacagcag ttaatcaggc
    39361 cattaactat atttatccag atcgagataa ccgtgtggtg cattcaacct ctttaattga
    39421 ctaagggagt cggaagtttc aagagcagta gcaacagcta atattcagtt tgtcaggaga
    39481 ggacaaatgg tttttaccta agtcttcgtg acaagtttta tactttgtga taaaatagtc
    39541 attgtgaaaa aagtgtgatg gttttcacag attaacacat tacaatgaaa aggggtctat
    39601 catgacaaca acagataaag agacatttag ttcttttatg aataaggtct tggctggtac
    39661 agcgattgct atcgttgtgg cactcattcc aaatgctatt ttagcgactt tcttaaaacc
    39721 gcttttgcca aacatggcag ctgctgaatt tttacacatt gtgcaagtct tccaattctt
    39781 cacgccgatt atggctggtt tcttgattgg gcaacaattt aagtttaatc ctatgcaaca
    39841 gttggctgtt ggtggagcag cctatattgg ttctggagcc tgggcttata cagaagtcat
    39901 tcaaaaaggt gtggcgacag gaacattcca acttagaggt attggggatc tcatcaatat
    39961 gatgattaca gctagccttg cggttttagc tgtgaaatat tttgggaata aatttggctc
    40021 tttaaccatt atcttgttac ctatcactat aggaactggc gtaggttata ttggttggaa
    40081 atttttgcct tatgtgtctt acgtgacaac cctgatcgga caagggatta attcttttac
    40141 aaccttacaa cctattttaa tgtctatttt aattgcagtt gctttctcgc ttatcattgt
    40201 tagtccgatt tcaactgttg caatcggttt agctattggg cttaatggaa tggctgcggg
    40261 agcagcttct atgggaattg catcgacagc agcagtctta gtgtgggcga cgcttaaagt
    40321 taataaatct ggtgtaccaa ttgctatcgc acttggggct atgaaaatga tgatgccaaa
    40381 cttcttgaaa catcctatca tggctattcc gatggtgttc actgcagcaa ttagctcatt
    40441 aacagtacca ttgtttaatc ttgttggaac accagcttca tctggttttg gcttagttgg
    40501 tgcagtaggt ccgattgctt ctttagcagg tggtagctca atacttatta ttatccttgc
    40561 ttggatcatt gttccgtttg cggttgcttt tgcggcgcat aaggtttcta aagatattct
    40621 aaaactttat aaagaagaca ttttcgtctt tgaaggctaa taggaggaaa atatgttagt
    40681 ttatattgct ggctcaggag ccatggggtg ccgttttggt taccaaattt caaaaacaaa
    40741 taacgatgtg attttgttag ataactggga agatcatatc aatgccatta aagaaaacgg
    40801 gttgattgta acaggtgatg tggaagaaac agttaagctt cctattatga aaccgactga
    40861 agccactcaa gaagccgatt tgattatctt gtttacaaaa gcaatgcagt tgccacaaat
    40921 gcttcaagac attaaaggca ttattggaaa agaaaccaaa gtgctttgcc ttttaaatgg
    40981 tcttggacac gaagacgtta ttcgtcagta cattccagag cacaacattt tgatgggggt
    41041 cactgtctgg actgctggtc tagaaggtcc tggtcgtgct catcttcaag gtgtgggagc
    41101 acttaactta caaagcatgg atccaagcaa tcaagaagct ggacaccaag tggctgattt
    41161 gttaaatgaa gctaacttga atgcgactta tgatgagaat gttgtgccaa acatctggcg
    41221 aaaagcttgc gtgaatggta ccatgaactc aacttgtgcc cttctagatt gtacaattgg
    41281 tgaattattt gccagtgaag acggtctcaa aatggtaaaa gaaatcatcc atgagtttgt
    41341 tatcgttggt caagcagaag gtgtcaaact aaacgaagaa gaaatcacac aatatgtaat
    41401 ggatacatct gttaaagctg ctcaccatta cccatcaatg caccaagacc ttgtgcaaaa
    41461 tcaccgattg actgaaattg attttatcaa tggtgcagtc aataccaaag gtgaaaagct
    41521 tggtatcaat actccatact gccgtatgat tacagagcta gttcacgcta aagaagcagt
    41581 gttgaacatc caataaacgc tatcaaatcg ttatactcaa tattatggct aaagctttaa
    41641 tattgagttt tttgttatgc tgatagtatt tttcctaggc gtcattattt gtgagcctag
    41701 attatgagtt aataaaagaa ataataattg gtagaatttg atagattttg aaaggttatg
    41761 cttgactttt agttataaaa tagtataata attgtaaacg atttcagtta ggggtggttc
    41821 tatcttaaaa tcaaaacgaa aacaattaat catggcaaag atcactgaag aaaactatgt
    41881 ttctttagag gatttaatgc aattactcaa ctcctctgag tctactatcc gtagagatct
    41941 aggagagttg gagcaagaag gacggctaca tcgtgttcat ggaggtgctg aactttttca
    42001 ctctttacaa gaggaacttt ctaaccaaga aaagtctgtc aaaaacagtc atattaaaaa
    42061 agctattgcg caaagagcct ctcagtttat ctatgacaac gatgtgatct ttattgatgc
    42121 tgggacaacg actgaatttt tattaccttt tttacaagct aaaaatttaa ctgtagttac
    42181 taattctatt catcatgctg ctagattagt tgaactctct attgagacga ttattgtagg
    42241 gggttatgtc aaacaaacga ccgatgccag tattggtaat gtagctttgg aacagattag
    42301 gcagatgaat tttgacaagg catttcttgg aatgaatggt gttgatgatt cttacctgac
    42361 gactcctgat atggaagaag cagttattaa aaaagcggtt ctgtcaaatg caaaattagc
    42421 ttacatttta gtagatggca ctaaaattgg tcaggtatcg tttgtaaaag tagctcctat
    42481 taatgatgtg actattatta cattaggagg atcagcaagt attcttaaac aaataaagga
    42541 aaaggcaaag gtgattgaat tatgatttat accgtgacct taaacccttc tattgacttt
    42601 attgtcagaa ttgaccaaat aaatcttggg tcagtgaatc gcatggcgag tgatgataag
    42661 tttgctggag gtaaaggcat taatgtgagt cgtatcttgc aacgtttaga cattactagc
    42721 acggcgacag ggttcttggg tggttttaca ggacgtttta tcgaagaaag tttgagtgca
    42781 gaaggcgtta aaactgattt tgtaaaaggt gatcaagata ctcgaatcaa tgttaaaatc
    42841 aagtcacaag aagagaccga attaaatggt caaggaccta tcattagtcg ggaacaacta
    42901 gaggagttga aaactaagct ttcccagcta acagcagagg atacagttgt ctttgcaggt
    42961 tcagcgccag ctaatcttgg caatgctgtt tataaggaat tacttccttt agttaggcaa
    43021 agcggtgctc aggtggtttg tgattttgaa ggacagactt taatagatgc gcttacatat
    43081 aatcctctgt tggttaaacc taataatcat gaactagaag ctatttttgg tacgattctg
    43141 actagtcttg atgatgttga aacctatgcc cgtcgtcttt tagagatggg tgctcaaaac
    43201 gtcatcattt caatggctgg tgatggtgct ttgctggtta ctaaagaagc gacttatttt
    43261 gctaaaccga ttaagggaga agttaaaaat tctgtcggtg ctggtgattc gatggttgct
    43321 ggctttacag gcgaatttat gaagagtcaa aatccaatag aagccttaaa atggggcgtg
    43381 gcttgtggta cagcgacggc tttctctgat gacttggcga caattgcatt tattaaggaa
    43441 acatatcata aagttgaggt agaaaaacga tgaaaattca agatttattg agaaaagata
    43501 ttatgattct cgatttacag gctatttcta aagaagttgc cattgacgag atgattacta
    43561 aattagttga aaaagatatt gtacatgatt ttgatgtctt taaaaagagt atcatgatac
    43621 gtgaagaaca aacatcaaca gggcttggtg atgggattgc catgcctcat tctaaaaata
    43681 ttgtagtaga taaaccagcg gtcttgtttg cgaaatcaaa taaaggcgtg gattataagg
    43741 ctttagatgg tcaaccaacg gatctcttct ttatgattgc tgcgcctcaa ggagcaaatg
    43801 atactcactt ggctgcgcta gcagaattat cacaatacct tttgaaagac ggctttgctg
    43861 ataaacttcg tgctgcagcg acaccagaag cagtcattgc tgtttttgat gaagcgtcaa
    43921 cagctaaaga agaagtggtt gctccaacaa gtggtcaaga ctttatcgtt gctgttacag
    43981 cttgtccgac aggaattgct cacacttata tggcagaaga ggctttgaaa aaacaagctg
    44041 cagaaatggg agtagctatt aaagttgaaa caaacggtgc ttctggtgtg gctaatcgtt
    44101 taaccgctga agatattcag agagctaaag gagttattgt tgcagctgat aaagcggttg
    44161 aaatggaccg ttttgatggt aaacaattca ttgctcgccc tgttgcagat ggtatcaaga
    44221 aaagtcagga attgatttct ttgattttaa acaatgaagg aaacacttat catgctaaaa
    44281 atggaaaatc tgaaacagca gtatcaactg agaaaacaag tttaggcggt gctttctata
    44341 aacacttgat gggcggtgtc tcacaaatgt tgccatttgt tattggtggc gggattatga
    44401 ttgctctagc atttttattg gataacatgc ttggtgtgcc aaatgatcag cttggaagtc
    44461 ttggatccta tcatgaaata gcagctattt ttatgaacat tggtggagca gccttttcct
    44521 tcatgttacc agtactagca ggttatatcg cttattctat tgctgaaaaa ccgggcttag
    44581 tagctggttt tgtggcaggt gccattgcct caaatggtct tgcttttggt aaggtaccat
    44641 ttgcagcagg aggagaagtg agcttgggct taacgggcgt gccatcaggt ttccttgggg
    44701 cgcttgtggg tggtttcctt gccggtggtg ttattcttgc ccttcgtaaa ttgttggcag
    44761 gcctaccacg ttctctagaa ggggttaaat ctatcctcct ttacccatta cttggcgtcc
    44821 ttgtcactgg tttcttgatg ctttttgtca atattccaat ggcagctatt aacacagccc
    44881 ttaatgattt cttacaaggt ctttcaggaa gctctgctgt ccttatggga cttcttgttg
    44941 gtggaatgat ggctgttgac atgggtggtc ctgttaataa ggcagcttat gtttttggta
    45001 caggaacttt agcagctact gtggcaaatg gtggttcggt cgttatggcc gctgttatgg
    45061 caggtggtat ggtacctcct cttgctgttt ttgtagccac tctcttgttt aaagataaat
    45121 ttaccaaaga agaacgtgaa tcaggcttga caaatattgt tatgggactt tcattcatca
    45181 ccgaaggagc aattccgttt ggtgcagctg acccagcacg tgcgattcct agctttatcg
    45241 caggttctgc cttgacagga gctcttgttg gtttggctgg tattaaatta atggcgccac
    45301 atggtggtat cttcgtaatc gctttaacaa gcaatccaat cttatatctt gtctttgttg
    45361 tgattggcgc ccttgtatca ggtatcttat ttggcgctct tcgcaaaaaa gcctaaaagg
    45421 taaagaactt ttttcttact aaaactagaa tctgtcaagg ttctagtttt ttgctatact
    45481 agagttaaag gataagaaac gaggaccttt gaaggtgaaa aaaaggagaa gaagggctaa
    45541 atcatcagta aatcgacttg tcttagggtt agtattactt aatctgattg ttagtatgtg
    45601 gacactaaaa ttgggaaacc agcgattagc tccgtatgcg gatcacgaaa ctctgacatt
    45661 tgtcaggaag attagtcatg ctgctcaatc agtcgctcaa aagaaacagt tatacagttc
    45721 ggtgatgatg gctcaggcca ttttagaatc caataatggc aagtcacaac taagtcaaaa
    45781 accttattat aattttttcg ggattaaggg gagctataaa gaacggtcag tcatttttcc
    45841 aactttagaa gacgatggac aagggaatct ttatcaaatt gatgctgctt ttcgttccta
    45901 tgggagcctg acagcttgtt ttttagatta cgcaagagtt ttgaatgatt cactttatga
    45961 caaaacccac aaaaagtttt ggtctcatta tcaagatgct actgcaacct taacaggcac
    46021 ttacgccact gatacaactt accataccaa attaaatgaa ttgattgaat ggtatcaact
    46081 cactaatttt gatggtctaa tgaaatagtt atccacaatt ttaaaaaaat cagaagaaat
    46141 atgtcgattt caagacaaaa gttatcaatc tcattaaatt atctgtggaa aagttaattt
    46201 aaacgttcgt gtgctataat agaaacatag aaaatgtata aaaaaggata tgtgaataat
    46261 gacaaaaaag aaaggtaagc ttgtacttat cagtcttttt gttctagcag cttgtttagg
    46321 agcttatagt gcaatgagac aatctcataa aacttcaaac gtgtcagctg agactatcgc
    46381 cagttcttca acccgacatt ttattgatga aattggtcca actgctagta ctattggtca
    46441 agaacgtgat ctttatgcgt ctgttatgat agcacaagcg attttagaat caagtaatgg
    46501 taaatcaagt ctaagtcaag caccttatta taattttttc ggtattaagg gtgcctataa
    46561 cggttcttct gtgacgatgt caacttggga agatgatggt aatggcaata cctatacgat
    46621 tgatcaagcc tttagagctt atccaagtat tgcagactcc cttaatgact atgcagactt
    46681 gctaagttct agcacttata taggtgctag aaaatcaaac acgctatcgt atcaagatgc
    46741 tacagcagct ctaactggct tatacgctac agacaccagt tataacttaa aactaaataa
    46801 tattattgca acctatggtt tgacggctta tgatgttgct aatagcgcag ctcaagaaac
    46861 tggtctagca acttcgggtt atgtttggaa tgagtatcgt cgtaattaca ctgatgcgga
    46921 gaccctagca gttgatgagg cttgggctaa acgcatgact tattaatgta acactaacaa
    46981 caatctgctt gcactgaccc caaaaaagct ggatactcta ttttaagtaa aggatttagt
    47041 tctgtattgt acagaactaa atccttttag ttttactttg atatgtttat cgttgtaata
    47101 atcaatgtca tttgtaatcg cttgttctaa gtcttctagt gatttatagt tattctcata
    47161 accatagaac atttctgact ttaagatgcc aaagaaagat tccatcatgc cattgtcagg
    47221 actgtttctt ttacgtgaca tagacggacg aattccttta gagtttagga aatgatgata
    47281 atagttgtgt tgatattgcc aaccttgatc actctatcat atagttccat catagcattt
    47341 atttggagat gtctttttcc attattggtt taatgtgatt taagcaaggt tattagctaa
    47401 acttaatgcc agacaaaaac accccaatta ttagattttt tgtctaactt ttggggcgca
    47461 attcaatctg agcagtttta gatttggtat caatgttatt ataggtcaat tgatcatatt
    47521 tatccaaagc ttttagctta tttagtccaa agataaatat caaaatggct gaaatctttc
    47581 atgtttatag tcttattgtc tttatatttt tttaagacat cagatctggt gctattgggt
    47641 tttgcgtcat ataaattgat tttttcatgt ttcctatttt tactgtg
//
LOCUS       DAUCXI010000013        44783 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.013, whole genome shotgun sequence.
ACCESSION   DAUCXI010000013 DAUCXI010000000
VERSION     DAUCXI010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44783
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.013"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            16..303
                     /locus_tag="VGY43_000709"
     CDS             16..303
                     /locus_tag="VGY43_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-damage-inducible protein J"
                     /protein_id="HEQ4301918.1"
                     /translation="MTTVKKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNV
                     VVTNEVDLLTEEELEKEKLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
     gene            293..628
                     /locus_tag="VGY43_000710"
     CDS             293..628
                     /locus_tag="VGY43_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ4301919.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGQRKMEQIISD
                     IEKLEVFPEVGFEADEKYGSKISHYHSTKGYTLSKDYIVLYHIEGEENRVVIDYLLPT
                     QSDYIKLFK"
     gene            780..1250
                     /locus_tag="VGY43_000711"
                     /pseudo
     CDS             780..1250
                     /locus_tag="VGY43_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
     gene            1213..1713
                     /locus_tag="VGY43_000712"
     CDS             1213..1713
                     /locus_tag="VGY43_000712"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ4301920.1"
                     /translation="MAALRKGELCALKWADIDFQSETLSVNKSLGRLDGQAIEKSTKN
                     DFSVRKIKLDSETLSILQEWKAICQKEKAQLAVAPLSIESDFIFTYCTREGSIEPLHA
                     DYINNILSKVIKQHSLKKISPHGFRHTHATLMIEIGVDPVNTAKRLGHAISQMTLDTY
                     SHATAV"
     gene            complement(1881..2273)
                     /gene="rpsI"
                     /locus_tag="VGY43_000713"
     CDS             complement(1881..2273)
                     /gene="rpsI"
                     /locus_tag="VGY43_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEQ4301921.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(2294..2740)
                     /gene="rplM"
                     /locus_tag="VGY43_000714"
     CDS             complement(2294..2740)
                     /gene="rplM"
                     /locus_tag="VGY43_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEQ4301922.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(2958..3164)
                     /locus_tag="VGY43_000715"
     CDS             complement(2958..3164)
                     /locus_tag="VGY43_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4301923.1"
                     /translation="MKNLKLKAARAGKDLSQQALADLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEADDSR"
     gene            complement(3161..3859)
                     /locus_tag="VGY43_000716"
     CDS             complement(3161..3859)
                     /locus_tag="VGY43_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301924.1"
                     /translation="MFDSKQNLAKSQWMFIIIIAVMDLVVLVATLLAKTSFQRYLVGG
                     VAVILTSFLILLVWGLKTAKKLQMRLDSKEVLDSKVRDDQKLPKYDERQKQILLKGYT
                     IGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGGLAVQTTYCNLNGVSPFVDRRF
                     GKQGILMGMIATGMSLVTIGLAVREMMAGQLKMGSFFKAGGSGSLMVLGITLLSMGAS
                     IFYRHYLDAKEADE"
     gene            complement(3995..4855)
                     /locus_tag="VGY43_000717"
     CDS             complement(3995..4855)
                     /locus_tag="VGY43_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEQ4301925.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNSR"
     gene            complement(4952..5470)
                     /locus_tag="VGY43_000718"
     CDS             complement(4952..5470)
                     /locus_tag="VGY43_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEQ4301926.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     SQLKDFMSQLDR"
     gene            complement(5474..6220)
                     /gene="rlmB"
                     /locus_tag="VGY43_000719"
     CDS             complement(5474..6220)
                     /gene="rlmB"
                     /locus_tag="VGY43_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEQ4301927.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDVDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            complement(6267..7064)
                     /locus_tag="VGY43_000720"
     CDS             complement(6267..7064)
                     /locus_tag="VGY43_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301928.1"
                     /translation="MTTMQKTVSLLSLALLIGLLGTSGKAISVYAQDQHTDNVIAEST
                     ISQVSVEASMRGTEPYIDATVTTDQPVRQPTQATITLKDASDNTINSWVYTMAAQQRR
                     FTAWFDLTGQKSGDYHVTVTVHTQEKAVTGQSGTVHFDQNKARKTPTNMQQKDTSKAM
                     TNSVDVGTKAQTKQSANQEIDSTSNPFKSATNHRSTSLKRSTKNEKLTPTASNSQKNG
                     SNKTKMLVDKEEVKPTSKRGFPWVLSGLVVSLAAGLFIAIQKVSRRK"
     gene            complement(7260..7673)
                     /locus_tag="VGY43_000721"
     CDS             complement(7260..7673)
                     /locus_tag="VGY43_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEQ4301929.1"
                     /translation="MTNPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            complement(7666..9009)
                     /locus_tag="VGY43_000722"
     CDS             complement(7666..9009)
                     /locus_tag="VGY43_000722"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEQ4301930.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNPRVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKAIHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLKVDIEALIAKRQEARANRDFATADAIRDQLAAQGIKLLDTKDGVRWLRD"
     gene            complement(9037..9267)
                     /locus_tag="VGY43_000723"
     CDS             complement(9037..9267)
                     /locus_tag="VGY43_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301931.1"
                     /translation="MNKIRVGLYVIMSLSILVFSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            complement(9746..10327)
                     /gene="cysE"
                     /locus_tag="VGY43_000724"
     CDS             complement(9746..10327)
                     /gene="cysE"
                     /locus_tag="VGY43_000724"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEQ4301932.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTIRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            complement(10336..11088)
                     /locus_tag="VGY43_000725"
     CDS             complement(10336..11088)
                     /locus_tag="VGY43_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEQ4301933.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSVALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMFLFKEEQKSAQSQYWLERSALAVLEEVITSGAAGLVFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDDNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            complement(11081..13213)
                     /gene="pnp"
                     /locus_tag="VGY43_000726"
     CDS             complement(11081..13213)
                     /gene="pnp"
                     /locus_tag="VGY43_000726"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEQ4301934.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKQANGATVVRYGDSTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIVAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAIDRTKEIIAGLVREAKV
                     GEVYHAKVIRIEKFGAFVNLFDKTDALVHISEIAWTRTANVSDVLEVGEDIDVKVIKI
                     DEKGRVDASMKALIPRPPKPEKKEEKHD"
     gene            complement(13493..14224)
                     /locus_tag="VGY43_000727"
     CDS             complement(13493..14224)
                     /locus_tag="VGY43_000727"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HEQ4301935.1"
                     /translation="MMTKKLNIKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGI
                     SSYIGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGES
                     TCPLIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTARVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICRQKEGVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDAKH"
     gene            complement(14234..15613)
                     /locus_tag="VGY43_000728"
     CDS             complement(14234..15613)
                     /locus_tag="VGY43_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEQ4301936.1"
                     /translation="MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGP
                     ILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVPNNEAVTSVAQKILGVETMSILV
                     VGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILGGFLLGAWS
                     AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSF
                     LRNTTISTGLIMVIFYLVATVASVLRNASVTEELAAGQNPFIFAIKSGLTFAVGVAIV
                     YAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVIIGFASSFVGGLLGM
                     LILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLP
                     VLGKLGFSNTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLTIVLVLPSFLSKSQE
                     AINNVSEEI"
     gene            complement(15640..15924)
                     /locus_tag="VGY43_000729"
     CDS             complement(15640..15924)
                     /locus_tag="VGY43_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ4301937.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKGADLFVTVKEFEDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            complement(15917..17977)
                     /locus_tag="VGY43_000730"
     CDS             complement(15917..17977)
                     /locus_tag="VGY43_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ4301938.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQDERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVISGSWVFSYLLHELGLPDQTKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRAEAVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKSVNEDEVAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPEKGTRQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            complement(18329..18598)
                     /gene="rpsO"
                     /locus_tag="VGY43_000731"
     CDS             complement(18329..18598)
                     /gene="rpsO"
                     /locus_tag="VGY43_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEQ4301939.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            complement(18774..18974)
                     /locus_tag="VGY43_000732"
     CDS             complement(18774..18974)
                     /locus_tag="VGY43_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301940.1"
                     /translation="MTMLGYRLSAEVLGSAILPLLAGYLIRQAIAQVYSDLKTAFWLF
                     GLASSVAYGGLVKAKRAHSMTR"
     gene            19100..19369
                     /locus_tag="VGY43_000733"
     CDS             19100..19369
                     /locus_tag="VGY43_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ4301941.1"
                     /translation="MTQNVCQQNITYIVKERFASYILKAQANQEVHLNFILLANRFET
                     SDRHLKHVLKQPIFQRIIERICFKTYRIADLDALTQLRPLRYAVH"
     gene            19470..20084
                     /locus_tag="VGY43_000734"
     CDS             19470..20084
                     /locus_tag="VGY43_000734"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEQ4301942.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(20118..20660)
                     /locus_tag="VGY43_000735"
     CDS             complement(20118..20660)
                     /locus_tag="VGY43_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ4301943.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKETKANLLSQAEALLAAI"
     gene            complement(20790..21218)
                     /locus_tag="VGY43_000736"
     CDS             complement(20790..21218)
                     /locus_tag="VGY43_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEQ4301944.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            complement(21328..25725)
                     /locus_tag="VGY43_000737"
     CDS             complement(21328..25725)
                     /locus_tag="VGY43_000737"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEQ4301945.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYENDKLIIAAPRFVNNDHFRKNHLPNLVKQLEAFGFGTLTID
                     MVSDQEMTEHLTKDFVSSRQALVEKAVQDNLEAQKSLEAMMPPVEEATSAPKFDYKER
                     AAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRAKKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGGGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     ILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLQPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHYPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMGILGNMPEDNQLSLFDDFF"
     gene            complement(25979..27835)
                     /locus_tag="VGY43_000738"
     CDS             complement(25979..27835)
                     /locus_tag="VGY43_000738"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEQ4301946.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPART
                     DLDRWVVLDKSVASMDDIPKEVLEEIKAELAAWMISGEDTIAYSTESSYAANLEMATN
                     EYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQAAQDLTAKLEADLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            complement(28033..29292)
                     /gene="rseP"
                     /locus_tag="VGY43_000739"
     CDS             complement(28033..29292)
                     /gene="rseP"
                     /locus_tag="VGY43_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEQ4301947.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHA
                     KTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNALKGLITGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLYLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            complement(29365..30159)
                     /locus_tag="VGY43_000740"
     CDS             complement(29365..30159)
                     /locus_tag="VGY43_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEQ4301948.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPRVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            complement(30172..30921)
                     /locus_tag="VGY43_000741"
     CDS             complement(30172..30921)
                     /locus_tag="VGY43_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEQ4301949.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNRRQRRFGKV"
     gene            complement(31140..31505)
                     /gene="yajC"
                     /locus_tag="VGY43_000742"
     CDS             complement(31140..31505)
                     /gene="yajC"
                     /locus_tag="VGY43_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEQ4301950.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETSVVN
                     EPAVETVDSTDTDSAIESH"
     gene            complement(31621..31995)
                     /locus_tag="VGY43_000743"
     CDS             complement(31621..31995)
                     /locus_tag="VGY43_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HEQ4301951.1"
                     /translation="MRPKEKETSMTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRS
                     SCPYCRRFAPKLAQVATDNQKEVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQ
                     HQRAVCDSSLTPDDILAFLTRE"
     gene            complement(32110..35607)
                     /locus_tag="VGY43_000744"
     CDS             complement(32110..35607)
                     /locus_tag="VGY43_000744"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEQ4301952.1"
                     /translation="MKKKVNQGSKRYQYLLKKRGIGFVIAATGTVMLGCTPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSGDGFQSSSKEAKPVLDSSSTNPDSIAEHHLRMHFKT
                     LPAGETLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDKDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYAYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTKVLGQANL
                     TKSDKGVWRAHLTSDSIKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNNATAT
                     DDIKTAKAAFIDPSKLGPAGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYKTKVS
                     DDKVPNKATLIDAVAQYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDGIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLLRAQVLADAEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKV
                     SSKTANPSQQKSQTDNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEAPSKGLLA
                     AGVALLLLAISLLMKRQKD"
     gene            complement(35805..37418)
                     /locus_tag="VGY43_000745"
     CDS             complement(35805..37418)
                     /locus_tag="VGY43_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEQ4301953.1"
                     /translation="MKKHWWHKATIYQIYPKSFKDTNGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIADVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
                     RQPDLNWENEALRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDSEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAKELDVPALKAIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVDDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSKAQETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFATDLAGAQ
                     VIIANTDVDTVLETKHLQPWDAFCLKLKA"
     gene            complement(37547..38680)
                     /gene="ugpC"
                     /locus_tag="VGY43_000746"
     CDS             complement(37547..38680)
                     /gene="ugpC"
                     /locus_tag="VGY43_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEQ4301954.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLDIAIPEG
                     QAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            complement(38978..39826)
                     /locus_tag="VGY43_000747"
     CDS             complement(38978..39826)
                     /locus_tag="VGY43_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEQ4301955.1"
                     /translation="MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLYETSQFIYLNHQQALPADLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQFLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
     gene            40166..41464
                     /gene="ska"
                     /locus_tag="VGY43_000748"
     CDS             40166..41464
                     /gene="ska"
                     /locus_tag="VGY43_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023611186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HEQ4301956.1"
                     /translation="MKNYLSFGMFALLFALTFGTVKPVQAIAGYEWLLDRPSVNNSQL
                     VVSVAGTVEGTNQEISLKFFEIDLTSRPAHGGKTEQGLRPKSKMPYKLEKADLLKAIQ
                     EQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDDSVTLPTQPVQEFLLSGHVR
                     VKPYQPKAVHNSAERVNVNYEVSFVSETGDLDFTPLLRNQYHLTTLAVGDSLSSQELA
                     AIAQFILSKKHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYHIKDREQAYKANSKT
                     GIEEKTNNTDLISEKYYVLKKGEKPYDPFDRSHLKLFTINYVDVNTNKLLKSEQLLTA
                     SERNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGKVEDNHDDTNRIITVYMGKRHE
                     GENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPKDK"
     gene            complement(41562..42005)
                     /locus_tag="VGY43_000749"
     CDS             complement(41562..42005)
                     /locus_tag="VGY43_000749"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEQ4301957.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDNAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     RQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(42020..44239)
                     /locus_tag="VGY43_000750"
     CDS             complement(42020..44239)
                     /locus_tag="VGY43_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEQ4301958.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKADVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGQDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLSFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVPDVYSVKRTNG"
     gene            complement(44491..44601)
                     /locus_tag="VGY43_000751"
                     /pseudo
     CDS             complement(44491..44601)
                     /locus_tag="VGY43_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_129544913.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
BASE COUNT        13074 a        10005 c         8479 g        13225 t
ORIGIN      
        1 aaggggttac ataaaatgac tacagtaaaa aaaaacagag cggttacctt tcaagctaat
       61 aaagaattgg taagcgaagc aatgacagta ttaaacaaaa aaaatttaac cttatcatct
      121 gctttaagat tattcctaca aaatgtcgtt gtcacaaacg aggttgactt attgacggaa
      181 gaggagttag agaaagaaaa acttttcaag caatttcaag ctgaaatcaa caaaaatatt
      241 gaggatgttc gtcaagggaa gttttatacc tctgaagaag tgagagctga acttggacta
      301 taagaaatat cagattatct atgctcctga tgttttagag aagctaaaag aaattcgtga
      361 ttatatttct caaaactatt cctcaacatc aggtcagcgt aaaatggagc aaatcattag
      421 cgacatagaa aaactcgagg ttttcccaga agttggtttt gaggctgatg aaaaatatgg
      481 ttcaaaaatc agccattatc acagcactaa aggttacacc ttaagtaaag attatattgt
      541 cctataccat atcgaggggg aagaaaatag ggtcgttatt gattacttgc ttcctactca
      601 aagcgactat ataaagttat tcaaataaca cgttaaaagc cttagcagtc ttgctagggc
      661 ttttttggta gattaccaat taactaggag caaaatgagt tcgggctgtt tagtagatat
      721 tccacaaaga agccaaagac tacgaagcta ggctaatcta ccttaaggct tcaggaaact
      781 tggaggagtt cgccaagcca actcataaaa cttatagcga gatattcgag aaatggtatc
      841 aagcctatca agatacggta gagccaacca cggcttctcg tactcttgat ctgtttcgac
      901 ttcacattct gccagtcatg ggagaattgc ccattaacaa aacctcccct ttagactgct
      961 agaacttcat caccgataaa gcaaagacct ttaagaatat caagcaaatc aagtcctaca
     1021 ctgaaaaggt ctttgatttt gccatcaaga tgaaactgct caagcataac cctatggctg
     1081 aaatcattat gccaaagcgg aaaaagacac gaatagaaaa ctattggacg gttcaagaac
     1141 ttcaggagtt tttagccata gtacttcaga aagagcctta caagcactac gcactatttc
     1201 ggctactagc ttatagcggc cttaaggaaa ggcgagctat gcgctcttaa atgggctgat
     1261 atagactttc agagtgagac actaagcgtc aataagagcc taggacgatt agacggacag
     1321 gcaatcgaaa aaagcactaa aaatgatttc tcagtaagaa agattaagct agacagcgaa
     1381 actctttcca ttcttcaaga atggaaagcc atctgccaaa aagaaaaggc acaactagca
     1441 gttgcacctc tttcaattga gtctgacttt atatttacat actgtactag agaagggagt
     1501 attgaaccac ttcatgcaga ctatattaac aatatcttat caaaggtcat taagcaacat
     1561 agtcttaaaa aaataagtcc tcacggcttc aggcataccc atgcaaccct gatgattgag
     1621 attggagttg acccagtaaa tacagccaaa aggttaggac atgctattag tcaaatgact
     1681 cttgatacat acagtcatgc tactgcagtc tgagaggaca aatcaatcaa acaatttgct
     1741 aactatctca aaaataacta aataaacgta ttaaaccaaa tcaaaagttt tccgaaacgg
     1801 tatcaaaagc aaaaaacgac aaaaaaagca ccttgcaaga gacttgcaaa atgcttgtaa
     1861 tcgttgatgt aaagctgttc ttaacgtttt gagaattgtg aagctttacg agctttctta
     1921 agacctggtt ttttacgttc aaccatacgt gcgtcacgtg taagaaggcc agcgcgtttc
     1981 aatgaatcgc ggaagtctgg gtctacttga agaagcgcac gagcgatacc atgacggatc
     2041 gcacctgatt gtccaccgta accaccacca acaacgttaa cgaaaacgtc gtatgaacct
     2101 tcagttgatg taactgcaaa aggttggttg atgatcaaac gtaggtcagc atgtgggatg
     2161 tattcttcta catctttttt gttaacagtg attttaccag tacctggaac caaacgaacg
     2221 cgtgcaacag cgtttttacg acggccagta cctgcatatt gtgcttgtgc cattatttaa
     2281 tgctcctttc ctcttagata agtcctgaga tgtcaagtac ttctggttgt tgtgctgcgt
     2341 gagtgtgctc accgccaacg aagactttca atttcatacc ttgtgcacgt ccaagagtgt
     2401 tatgtggaag catgccttta actgattttt caatcaagcg aactgcgttt ttagagcgaa
     2461 gttcaccagc agtgattgat ttcaaaccac ctgggtacat tgagtgagtg tagtaaactt
     2521 tatcagttgc ttttttacca gttaatttaa ctttttcagc gttgataacg ataacaaagt
     2581 cacctgtatc agtgtgtggt gtgaaagttg gtttgttttt tccgcgaagt acgctagcaa
     2641 ctactgcaga aagacgtcca agtggcacat cagttgcgtc aacaacgtac catttgcgtt
     2701 caacttggcc tggtttagcc atgaaagttg ttttgttcat gatttctcct atacgaattc
     2761 gtaatatttg tttacaaggt gatgggtgtt ccgtcccatc gaaggtattt ggaaggttcc
     2821 ggggcctttc aaatggggta aacaataccg cctactatga tatcaaactt aagaggctcc
     2881 agtcaagtgc tttagctgat tttattggat tattttttct ttcgatttag gagaatggca
     2941 gagctgctct gctggtgtta acgagaatca tcagcttccc aaaaaaggtc gtctaaggtc
     3001 ttatcaagca ctcgacaaat ggcaatgcaa agattaatcg ttgggttgta atcacctttt
     3061 tcaacagccg caatggtttg tctggagacg cctaccaaat ctgctagagc ttgttgagac
     3121 aaatctttgc ctgcacgcgc tgcttttaat ttgaggttct tcattcatct gcctctttag
     3181 catccagata atgacgatag aaaatactag ctcccatact aaggagcgtt atgcctaaca
     3241 ccattaaaga tccactgccg ccagccttga aaaagcttcc cattttaagt tgccctgcca
     3301 tcatctctct taccgccaaa cctatagtga ctaagctcat tcctgttgct atcatcccca
     3361 ttagtattcc ttgttttcca aagcgcctat ccacaaatgg cgataccccg ttgaggttac
     3421 aatatgtcgt ttgaactgcc aaccctcccc ataaagccaa cgtaaagagg aagcttgcag
     3481 ataccagtcc ctctgtgaat cggctaataa agagtgacag ccagataacc acaatcataa
     3541 accaaaaccc aatagtgtat cctttgagaa gaatctgttt ttggcgttca tcatatttgg
     3601 gcaacttctg atcgtccctt accttagaat ctagtacttc cttgctgtct agtctcattt
     3661 ggagcttttt cgctgtcttt agcccccata ccaacaatat gagaaagcta gtcaatataa
     3721 ccgctacgcc tccaactaag taacgttgaa aactggtttt agccagcagt gtcgctacta
     3781 acacaaccaa atccatcact gctattatga ttataaacat ccattgtgac ttagcgagat
     3841 tttgtttgct atcaaacatg attcgtttct cctttaaatc tttacatgac ataatacaaa
     3901 ttattttgga tattttgtca aatatatttt acattcttga ttgatttaag cagcaaaaaa
     3961 ggattgagga tttctcttca atccttataa gggattaacg ggaattctgc ccaatcacaa
     4021 aaactgccag ggtgttagga ccaacgtgag ctgagataac tggtcctagt ggcatcataa
     4081 gaacatcgct aatattctca tgcgccagta gctcttctcg caacttttcg gcactaccct
     4141 gatcgcttgt ataagagaca ataaccgtcg aatccgcaat atctttttcc acttgagcca
     4201 ccatttcttt gatggctttt tggcgtcccc gaatttttgc aatgggcacc aatttccctt
     4261 cctcatcaat ccacaaaaga ggtttgatac tggctaaact gcctagaaaa gctgaacctt
     4321 ttgacagacg cccaccacgc atcaaatgaa aaagatcatc tactaagaaa taggtgcgca
     4381 gtcgagggat cactgcttca acaatatctt tagtctccag taaatttttg ccactatctc
     4441 tggcttctgc tgctaaaatg gttagatagc cttctcctcc tgcagcagcc aaggtatcaa
     4501 caatttcaat caccgcatcg ggataatctt ctcgaacaag atcgcgtgcc attagagcgc
     4561 tttgataggt acccgataaa accgaagaaa aagcaagata aagcagtgct ttgttgttcc
     4621 tagcatgttc acgaaaaacc ttctcaaact ctcccacatt aatctgactg gtttgaggat
     4681 gactgccagc tttcatcttt ttcaaaaggt aatcactact aatacggtta ggaccgaccg
     4741 tttcataaac ctctccatcg cacaaaatcg ttaatcctat aaggacaata tcatgatctt
     4801 ctgcccaggt ttgattcaaa tcagcggttg aatctgtcat tattgtaaag gtcattctta
     4861 cttctcctca tccagttttt tagtttgaca atcaaataat tattgtttta ttttatcaaa
     4921 aaaacccgca cttggcgagt cgtaattctc attatcgatc taactgagac ataaaatcct
     4981 tcaattgact aagctgtcct tggtcaaaag gccgcagttt aggcgttttg agatcaatat
     5041 ctctagacat tttatctaaa tcagctttga cagtatgaac tctttgctct aattctcttg
     5101 cagtgacacg aagagctcct tgagaaaaaa tcgtccattg ttcatttaaa tcactcgtag
     5161 ctacttctac catatgtata gccgtattta actctgctgc catgcgctca atgtagctat
     5221 ctgctgtttc gtcttcctct gtaaatacca ctgagatata atactggtca tatcgttgcc
     5281 ttagccccgg tacatattgg gcatcaaaaa cacaaataat attaatattc tcaaaatggg
     5341 cataatgatt aagttttgtt aaaagtgtgt tacgtgcctg atcaagctga tttgtcttaa
     5401 acaactgacg ggttgattgc caaaaggcaa tcatattata cccatctact aataatatcc
     5461 gttttttcat aatttagcgc ctatttcgga aaacttcata catgagaata gctgccgcta
     5521 cgctagcatt taagctctgt acgtgaccat tcataggaat cgtaatcatt tcatcaactt
     5581 gctttttgat attagtagag atgcctttgc cttcgttacc aatgactaaa gcaagtttac
     5641 cattagtgtt ccagcaatca gacggtgttc cattcatgtc tgtgccaaaa atccagaatc
     5701 ctcttgcttt caatttatct agagtttgac taaggttagt tactctcgct atcggaatat
     5761 gttcaacagc acctgtagat gtctttgaaa ccactggagt cacaccaaca gaacgatgtt
     5821 taggaataat cactccacat acatttgtag catcagctgt ccgtaaaatc gatcctaaat
     5881 tatgaggatc tgtcagacca tctaaaataa gaatcaaagg atttgcttct tgctctgcta
     5941 tttcgaggat ctcatcaaca tcagtatagg caaaagctga tactctcaga acaaaacctt
     6001 gatgcacagc tccatcagtc atttgtgaca aggttttttt aggcgtccat gaaatagcga
     6061 cctttttttg tgtcgctaag cttttgatgt tatccacttt ctttcctctt aaatcctctt
     6121 ggatataaag cttatttcct gtatttgctt gaaggctttc tgtaacggca tgaacaccat
     6181 agacgatatc gtttgtttca atagtatctt tatcttccat gagtttatta taccatgaat
     6241 gtttcaaaat aaatgcatag actcttttat tttcgtctag atactttttg aatagctata
     6301 aataaacctg cagctaaact gactactaga cctgataaga cccaagggaa tcctcttttt
     6361 gaagtaggtt ttacttcctc tttgtccact agcatttttg tcttgttgct accgtttttt
     6421 tggctattac tagcagttgg tgtaagtttc tcatttttag tagatcgctt taaggaagtt
     6481 gatcgatgat tagtagctga tttgaaagga tttgaagtag aatctatttc ttggttagct
     6541 gattgttttg tttgagcttt tgtgcctaca tcgaccgaat tcgtcattgc tttagaagta
     6601 tccttttgtt gcatattagt tggtgttttt ctagctttgt tttgatcaaa atgaacagtt
     6661 cctgattgac cagttactgc cttttcttga gtatgaacgg tgacagttac atgatagtca
     6721 ccactctttt gtccagttaa atcaaaccaa gctgtaaaac gacgctgttg cgctgccata
     6781 gtatataccc aactattaat agtattatca ctagcgtctt taagtgttat cgttgcctga
     6841 gttggttgtc tgacaggttg atctgtggtg actgtagcat caatataagg ttctgttcca
     6901 cgcatactgg cttcaacact gacctgacta atagttgatt cagctataac attatcagtg
     6961 tgctgatctt gtgcatacac agatatggct ttgccagaag tccccagcaa accaataagt
     7021 aaagctagtg ataataagct aactgttttt tgcatagttg tcataataaa tatctcctct
     7081 ttaaattagt cttaccctct cattataaac tattcgaaaa tgattccatt atttttatgt
     7141 cttttttgtt acaaatgtat cctttttata tcattatgtc tttttgatgt cataaaaaga
     7201 cttaatggct ctctaccttt acttcagatc tatgaaaata agagtctcct aggggactct
     7261 tatgaggata tcaattgttg cttttctaca tactcaatac accatctgat caattcttct
     7321 aaccgctctt tttggcccat catatcaaga taacccataa tggcttcaaa acctgtcgac
     7381 atacgatagg taataatatc ggcattctta gctttagtat ggctattggt attgcgacca
     7441 cgcttataga tgtcttcttc tttttcggtc aatagctgcg cttctaacat agcctgaatc
     7501 aagttggctt gtgccttagc agaaacatat ctcgttgcta aacggtgtag ctggctaggt
     7561 ttcgttttac cttgaaaaat gagatgacga cgaacatagt aggaataaac cgcatcccct
     7621 tcaaaggcta gggcaatacc attaatcaaa ttcacatcaa ctggattagt cacgcagcca
     7681 cctcacacca tctttggtat ctagcagctt gatgccttga gctgctaact gatctcgaat
     7741 ggcatcagct gtggcaaaat cacgattcgc gcgtgcttct tgtcgcttag caatcaaggc
     7801 ttcaatgtca accttaagca cctcttcttc aaagataatg ccaaaaacag ctaacatttt
     7861 ctcaaaagcg cttttaacag gttctgtata agagccagaa ttaatccact tggccatgtc
     7921 aaatacgacg gtaatcccat ttgctgtatt gaaatcatcg tccatagcgt cttggaaagc
     7981 tattacaaac tgttttagct cttgctcatc tgcagtttct gtcagcggtt gttgcaaggt
     8041 gtttttaaga tacttcagat tgatttccgc atcatgaata gccttttcag tgaagttaat
     8101 tggttttcgg tactgttgtg tcgcaagaaa gaatcgcaaa acctgaccat caacggtttg
     8161 taacatgtca tgaacggtca caaaattacc tagtgacttg gacatttttt cgttatcaac
     8221 agtgacaaac ccattgtgca tccaatagtt agcaaaagtc ttgcctgttt tggcctcaga
     8281 ttgggcaatt tcattggtat gatgaggaaa ttccaaatca gctccgccac catgaatatc
     8341 aatggtatca ccaagaattt cagtagccat cacagaacat tcaatgtgcc agcctggacg
     8401 accaaacccc caggggctat cccaagaaac ctcacctgcc ttagctgatt tccaaagagc
     8461 aaagtccagt ggattttctt ttaaagctgt ctcagcatct gttcgaccac tggctccaac
     8521 ttcaagttct gacagggttt tattagctag cttggcataa tgctctgact tttccacgcg
     8581 gaaatacaca tctccatctg cttcgtaagc aaaatctttt tcaatgaggc tttcaacaaa
     8641 tgaaatgatt tctgctatat aatccataac acgaggattt tgtgtggctg gcttaacacc
     8701 aagtgccttg gtatcttcta taaaagctgc aataaagcga tctgacaatt ctttaggaga
     8761 aacacctgct tgagtagcag ccttgataat tttatcatcg acatcggtaa aattggaaat
     8821 gtaattgacc tgatagccag tatactcaaa ataacgtcga atggtgtcaa aagcgaccgc
     8881 tgatctagca tttccaatat gaatataatt atagaccgtc ggtccacaaa cgtacatatt
     8941 gactgtattt tcagtcaaag gtacaaactt gcggagcgaa cgggtcatgg tatcataaat
     9001 tttaatcatg taaactcctt attcaatagc ctggcattag ttgtcatctt gatatcctaa
     9061 gtctttttct gaaatgctgt tccacctttt caacaatttg atattaataa ccaaacctat
     9121 taaccaaaat agggtcaaaa tgaagtatat aatcgcttta accatgtctt gtctcagtaa
     9181 aaaaattaga ctagccacca gtgtaatact aaaaacaagg atagacaaac tcataatgac
     9241 atacagccca actcttattt tattcatgag gctcctttat taacgaaaaa ccttcacaac
     9301 ctgtgaaggc ttcagaaagt agacaaaccc acttttatgc tcaaaaagca tgaatagatc
     9361 tactgatttg acatcaggtt tcctatttct gcatgtgggg tgagccaaaa cagctacttt
     9421 ttgttgtggt aaaagtggca tcaatattga cagtgatacc catacggatt tttgagatct
     9481 taggctcaaa actaaggtat ggaattccaa aggaagtcgc tgccgtaagc acaacctgag
     9541 aaaaagtatc acaatagact gtttcttcag tctaagactt gcttagttga tgctctttta
     9601 cgcgtttttt gtattttgta acattcccat atcactacac tcagcaacca aactgatagg
     9661 actagctaag ttcaacatta ctctactaga aagtccaaaa atattttatt ggaagtcatc
     9721 agtgcttctt tttgttattt tccgatcatt ttgacaactg ataagagacc tctcgttgtt
     9781 tttgtaaact ttgaatttga cgattatctt tttgtccatg cactcgtact atcttagctg
     9841 gcacacctac aactgtcacg tcttcaggaa catctgataa cacaacagct gctgccccta
     9901 ctttagcatt tgctccgatg tcaataggtc caatcacttg ggcatgtgcc gaaattaagg
     9961 caccttgtcg aatcgttgga tgacgcttgc cacaatcttt tccggttcca cctagggtca
    10021 ccccatgata aagcatcaca cctttttcaa caattgctgt ctctccaata acaagaccag
    10081 caccatggtc aatgaagact ccaggagcga tttgtgctcc aggatggatt tcaatttgtg
    10141 tccaaaatcg ccaaaattgg ctatgcattc tggctagtaa tttaaaatga tgtcgccaaa
    10201 gaaaatgaga caaacgatga gcagctaggg ctttgatgcc tggataagtt aggataacct
    10261 caagactatt acgagcagct gggtctagag ctttaacaat agctatactt tctttccacc
    10321 aacccatact aactcctacg acttatctaa ttctgaccaa tcaacaagaa tttgttggtc
    10381 atcaaaagga ttgatggcga caccgaacgt ttcatcaagc tcgttttcac catttcttgg
    10441 ttgataaata tcatcaatcg tccaagtcag aatcactcct tcagctttcc tgaaaaggcc
    10501 tccaaaatcg tcttggttgt accatttcgc aaagctttga agatttgaaa aggcgggaac
    10561 atagcttttt ccttcaggcg ttgacatggt aggaaaaagg cggtcgtaat ggttatcatc
    10621 tttaggataa acaaaggcgg gaacaaggta aaccttttcc atcgtatctg ccgccacatt
    10681 gtcatcactc ataagcgtat ttaacacagt ggtgtaatgg ttcataaatt gaatcatgtc
    10741 actgcttttg aaaatggtag aattcccaaa atctcccttt ttcttaaggt taaagacaag
    10801 acctgctgca ccagatgtaa tgacttcttc tagcactgca agagctgaac gctccagcca
    10861 atactgactt tgagcactct tttgttcctc tttaaagagg aacatatctt ccttatcggt
    10921 aaaaacaggg gtaaccttga caccttctac ctctatgacg tagggttctt tagcagccca
    10981 gacaggaaaa ttatggaaag cgttgacaag ggcaacacta tccaaaaaat tatcaggcgc
    11041 attgataaaa gctcttaagc gaatatctaa ttcatttgat ttagtcatgt ttttcttctt
    11101 ttttctctgg ttttggtggg cgtggaatca aagctttcat tgaggcatcc acacgaccct
    11161 tctcatcaat cttaatgacc ttaacatcaa tgtcttcacc cacttcgagg acatctgaca
    11221 cgttagctgt tctcgtccag gcaatttcag aaatatgaac aagtgcatct gtcttgtcaa
    11281 agaggttgac aaaggcacca aatttctcga tacggataac cttggcatgg taaacttcgc
    11341 ctaccttggc ttcacgaaca agacctgcaa taatttcttt agtgcggtca atggcagctt
    11401 ggtcacttga gtagatagag acatttcctt cgtcgtcaat atcaattttg acacccgttt
    11461 cggcaataat cttatcaata gtttcgccac ctttaccgat aaccactttg attttgtcta
    11521 cgtcaatctt gatggtgtca atttttggtg cagttggggc taactcagga cgtggttcag
    11581 cgatagttgc ttcaatcaca tcaagaattt caaagcgagc ttttttagct tgtgcaagag
    11641 cttcttctag gatttgaggg gtaattcctg caatcttaat atccatttga agggctgtaa
    11701 tcccttcacg agttcctgcc actttaaagt ccatatctcc aaagtggtct tcaagacctt
    11761 ggatatcggt caagactgta taattcgtcc cgtctgaaat gagacccatg gcaatccctg
    11821 ccacaggagc cttgattggt acaccaccag ccatcagagc aagggtacca gcacagatag
    11881 aagcctgaga agacgaaccg ttagattcta gaacttcggc aactaaacga atggcataag
    11941 gaaattcttc taagcttggc aagacttgtt caagagcgcg ttcacctaag gcaccgtgtc
    12001 caatttcacg acgaccagca gctccgtaac gacccgtttc accaactgaa tattgcggga
    12061 aattgtagtg gtgtaaaaag cgttttttgt actctggagc cagaccatca atgatttgag
    12121 tttctcccat tggtgccaag gtcaaaactg atagcgcctg agtttgacca cgtgtaaaga
    12181 gacctgatcc atgtactttt ggcaagaagt caaccacagc atcaagcgga cgaatttcgt
    12241 caatcttacg accgtcagga cgaatcttgt cctctgtaat gaggcggcgc acttcagcat
    12301 gctccatttg ttcaaggatt tctgccacgt cacgcataat ggttgctagg ttttcgtctt
    12361 ctgcgtaacg ctcttcgtac tcagccttaa ccatttcttt aacggcttct gtggctgctt
    12421 cacgcgcttt tttctcttca acttgaacag ctttttgcag ttgagcattg tacttagcca
    12481 caatatcagc ttgtaagtct gcatcaacct gtaacagttc aacctcagct ttctctttac
    12541 caacaactgc tacgatttgt tcttggaagg caattaattc ttgaatggct tggtgacctt
    12601 ttaaaagagc ctcaagcatg atgtcttctg ataattcttt ggcaccagat tcaaccatgt
    12661 tgatggcttc tttgctacca gcaacggtta attctaagag cgacgcttcc atttgttctt
    12721 tatctgggtt gatgatgaac tcgccatcaa tatagccaac ttgaacacct gcaatcggtc
    12781 cattaaatgg aatatctgag atggacaagg ccagagatga gccaaacatc gctgccattg
    12841 gagcgctagc attttcatca taagaaagga cagtgttaat cacttgtact tcgttacgga
    12901 aaccttcggc aaacatggga cgaatcgggc ggtcaatcaa gcgagctgtc aaggtcgcat
    12961 ctgttgaagg gcgtccctca cgtttcatga aacctcctgg gaatttacca gcggcataca
    13021 ttttttcttc gtaattaact tgaagaggga agaaatcacc cgttgccatt ttcttagaca
    13081 tgacagctgc ggttaggaca gttgagtcgc cataacgaac aacggttgcc ccattggctt
    13141 gcttagcgac ttgaccaact tcaacaacaa ggggtttccc tgcaaatgtt gttgtaaagg
    13201 tttgttttga catatattct ccttttaatt ttcagagggg taaagaggta cctgttctct
    13261 gcttagattc agttgttata cgttgttttg ctacaaaaag caacctgcca cgcttgtcac
    13321 aagctcctct ttgtatcaaa cgacgtatct gctacatttt accataaaat agcagaaatt
    13381 tcactgtcag atcgcaatct cttgaaatgt ccttgaaaaa tattaaacga aacttatact
    13441 ctttaacaaa gcaaaaaaag caggttggta tgcctgcttt cgtctcctaa tattaatgtt
    13501 tggcatcctc taaaatttta aagccgaggc tggtactgtc tttcagaaac atttgcacgg
    13561 tttcaaggga atagtcttct aaatcttttc cttgaagagg caacttggca atcaaatcag
    13621 tggtacaagt gataatgtcc acgcctagct gatcagcttg atagatatta taagtttcac
    13681 gaggactagc ccacaacaat tcgacccctt ctttttgacg acaaatgcgt agagcttctt
    13741 ccatgattgg cattgggtca acgccggtat ctgcaatacg accagcaaaa acagacacaa
    13801 tagctggaac tcgagcggtt aaatgatcaa ccacagcttg agtctgctca attgtaaaaa
    13861 tggctgtgac gtttaactta atgcctttgg ctgacaactt ttgaatgagg ggacaggttg
    13921 attctcctgt tgaagtggtg actggaattt tcacatagac attgtcacct agactggcaa
    13981 ttttctcagc ttccttttcc atgcttgcga gatcatccgc aaagacttca aaggacactg
    14041 ggtagtctgt aattttggca agcacttctt tggcaaagcc aatataagaa ctgatgcctg
    14101 cttttttcat caaacttgga ttggttgtaa agcctgtgac caaacctgtt tgtaaatcct
    14161 ttaacatggt ctctaagacc gcaccgtctg aaaagacttt aatgtttagt ttttttgtca
    14221 tcatatcctc cttttagatt tcttctgaaa cattattgat ggcctcttga gattttgaca
    14281 gaaagcttgg aagcaccaat acaatagtaa gcacagcaac caccaagtaa ataccgattt
    14341 gaccaatcga cgttcctaag cggcccagta aaatccctaa aacaccgaaa tccacatctc
    14401 caaaggtcgt gtttgaaaaa ccaagtttac caagtacagg tagaagcatg gctggcaaga
    14461 aggcgagtaa taagccatta gcgaaagcac caatcatcgc accgcgacga ccccctgttg
    14521 aatttccaaa aatccctgct gttgcaccac agaagaaatg aggcaccata cctgggataa
    14581 tcaggacacc acctgcaact cctaaaatca acatcccaag taagccacca acgaaacttg
    14641 acgcaaaacc gatgataaca gcggttggcg cataagggaa gaataccgca cagtctacag
    14701 ctggaatagc atttggaatt aatttgttag caataccttg gaaggctgga atcaagtcag
    14761 ccaaaatcat gcgaacaccg gcgtagacaa ttgccacacc aaccgcaaag gtaagaccac
    14821 tcttaatagc aaagataaat gggttttgac ctgctgctaa ttcttctgtt actgaagcat
    14881 tcctcaaaac agaagccact gttgccacca agtagaaaat caccatgata agtcctgttg
    14941 aaatggtggt gttgcgtaag aaactccatt tttcagaaat ctgaaggtcc tcggtatctt
    15001 tactgtcttt gccaaccttg ctaccaaccc aggcagaaag gtaatagccc aaactaccaa
    15061 agtgtcccat ggcgatttca tctccgtcag tcactttcag agtatactgt tgaccaatgg
    15121 ctggcgaaat agctgaccaa gctcccaaga ggaacccacc taagataatc aaaagacttc
    15181 ctttgaaacc aacagctcca agcacggcgg acaagagaca agccataaag aagctgtgat
    15241 gtcctgttaa gaaaatgtat ttgaagcggg taaaacgagc aaaagccaaa ttgagcaata
    15301 acccaaccac caagatggac atggtttcca cacccagaat cttttgagcg acagaagtga
    15361 cggcttcatt atttggcact acgccagtga tgctaaaacc gtgctcaatg agtttggcaa
    15421 gagggtccag attggtcaca ataacacccg cccctgcagc aagcataagg tatcccaaaa
    15481 tcggccccaa ggttcctgtc aacaccttat gagcaggtgt tttcaaagcc accaaccctg
    15541 caaaggcaat caagcccatt aaaaatgcag gttcttttaa aatatctcga ataaatgata
    15601 ataatgcttc catagtatct tcctatctcc tttaaaggct tattccttgc cactcatttc
    15661 cttgagaacc ggaaccaaat cttcttcaat ttttttacga ttggtatagc ttttaacgat
    15721 acaaaccttg gcatcctctg gaaaaatatc ttcaaattct ttaacggtaa caaacaaatc
    15781 tgcacccttt ccaacagccg cattggaatc acaggattct gcatccacat caatacccaa
    15841 actagaggcg atagcttcta ctttcatgcg aagtaacaag ctactaccaa taccgtttcc
    15901 acaaaccgtt acaattttaa tcatgtgatt catctccttt ttcaatcata tggctaatca
    15961 gactcattat ttcctcagta ttcttagcct caattaattg ctcaatatgt tcatcatcat
    16021 ctaaaatcaa cgacagttcc tgcaaagcct tcaaatgtga actagaatcc acagcagaca
    16081 aaacaaaaat caattgcact tgcttgtctg gatcaccttc ttgcttcaaa tcaaagctga
    16141 caggttcttt tagttgtaag agagacatgc ctaactgccg cgttcctttt tcaggcgccg
    16201 catgaggaac agccacctta ggggctaaaa caatataggc cccaagctca ttgaccgaat
    16261 caatcatgcc atcgatataa gatgtttcaa tcatctggtg ttctagtaaa ggctgagcag
    16321 ccaaacgaat cgcttcctgc caatccgaaa cagcatcagc ctgcctaata aaatctgctg
    16381 ttaacaagtc caatagtcct agacctcctt tttcaatcgt taaatggtta ccaatcaggt
    16441 aacgggataa atcactaaca agtccttctt tattagtaat cgtggtgtgt ttatgaataa
    16501 tactcaacag gtcatccaaa gcgaattgct ctgacaaggg aagatgaaaa tcatcacaga
    16561 ccatcttttt caacatcatt ttctcaacag gtcccatcaa agcttgcgtc acataaacag
    16621 gtttagcaca gtcaaaagct actgttgaaa aaatcaaatc aaaggaagct ggatccaaca
    16681 actttatttt gtccagctgg tgaatcctaa taaactgtag ctgtggaaaa agttccttca
    16741 aggttgcctc caacatcaga gacgaactaa tgccattagg gcaaacagat aaggctacca
    16801 gctgattgct tggcctcttc ttaggggcct gcaaccatct cccaaaatga atggtaaaat
    16861 aagcaacctc atcttcatta actgatttcc ccaattgttt ttctagagga gaaaggctgc
    16921 gcttgaccaa gtaaaagaga gattcataat cttgtttgat ttgttccttc aaaggattgg
    16981 tcaagttaat gtcgtagtaa agtcggtaat aagctggcaa aaggtgactg tataggttct
    17041 gacgaagttc tggggtatcg gtgatagaca atcccgtgtt aaccgccacc gaattgatga
    17101 tttcctccat aatgtcataa ataggttgct gaaagactaa ctctaagtca ccttggatac
    17161 aaccaagtaa cctagattga accaaatatt tttcttcggt tagactgggg aagttgacca
    17221 ataactggtc caccatcgtt tcaacagctg gcgaagctaa aggaaaagta tccactgctt
    17281 cagctcttac attccgtgaa aatggtcgat gagcgagaag gcagaaaaaa taaatcaaat
    17341 ccctcaattt ctccgaaata aaagttaagt ggttctccct gctcagttcc tccaacgttg
    17401 ctgccatcac ctttgtctgg tcgggcaaac caagttcatg caataagtaa ctgaacaccc
    17461 aagatcctga tatgacttgc aaaagagaac tgaccgctga ttctaagaga cgccgcaagg
    17521 ctaagggttc tccttcaaaa aaataaccat cctggcgatt gtaagctaaa gttacctgaa
    17581 aggcttgtac ccgatcacgc accaagttta aatcagcaat aacagaattt ctgcttaggc
    17641 gtaacaagct ttccaagtgg ttaatggaga taaattcttt agccatcatg atgtaaatga
    17701 taatcatgtc cagacgctca tcttgaaaga gatagtcgtc taaggtaggt agcatgcgat
    17761 tcaacaagtc cttttcagta aggtctggcg gataaaccag ctgcctgtcc agagcaataa
    17821 ggggtaactg atagagtgac aacgtgtcat tgattttagc aatatctgcc agtatatgac
    17881 gtttgcttgt ctttaatatg gattcaaatg cctccagtga atgtccttta tatttagaaa
    17941 agagttgata gtttctgatg agctcgtgag atagcatgtc atctcctcct ataatgtcag
    18001 tataaaatga agcgttttca ttttcaagac aaattgagtc caattgtctc tcgtcatttt
    18061 taactgcaat tggactcaac aggtgatatc attgtaacaa gttcctcaaa aggtggcaaa
    18121 aaataggcaa atctgggaat tgattccctt tttcttcatg atacaacaaa agatacctca
    18181 tcactgagat accttttgtt gctaaataaa atcatcaact gctaaaaaaa cagtcttaga
    18241 ccattctagc caaatgtgta agttaacaaa caacatgtca aaaatgaaaa agcccactgc
    18301 ataagcagag gactttttaa acttgaaatt aacgacgaag tccaagagat tggatcaact
    18361 cacggtaacg gttaacatct gtacgacgta ggtatgccaa caagttacga cggtgaccaa
    18421 tttttttcat caatccacgg taagtagcgt ggtctttttt gtgttctttg atgtggctgt
    18481 tcaagtggtt gatttcccat gtaagaactg ctacttgaac ttcaactgaa cctgtatcgc
    18541 cttcgtgacg tgcatattga gcaatgattt catttttttt ctcttttgag attgccataa
    18601 tatattctcc tttttttgct taatccgagt cctaggattg gcactcctaa aaccaagaaa
    18661 aagttggttt gtctttcgac cactctattc tagcagattc ataatattag gtcaaccgtt
    18721 atcctattat tctgagctct cacatccaaa ccacctcact aggcttaaaa aggttatctg
    18781 gtcattgaat gtgctctttt tgctttaacc aaaccaccat aagcaacaga actagcaagg
    18841 ccaaatagcc aaaaggctgt ttttaaatca gaataaacct gtgcgattgc ttgcctaata
    18901 agataaccag ctaaaagagg taagatggct gatcccagca cttcagctga taagcggtag
    18961 cctagcatag tcattcattt ctttccaata aagtgttcac tgataatatg aattgctcta
    19021 gtattaacaa acccaatccc taatccatga acacagctta ttaaccgatg ctacctgcct
    19081 ttatgacata ggtcaagagt tgacacaaaa tgtttgccaa caaaacatta cctatatcgt
    19141 caaagagcgc tttgcttcct atatccttaa agcgcaagcc aaccaagagg ttcatctgaa
    19201 ctttatatta ttagcaaacc gttttgaaac aagtgatcgc catcttaagc acgtacttaa
    19261 gcagcccatt tttcagagga ttatcgaacg catctgcttc aaaacctatc gtattgccga
    19321 tttagacgct ctaactcaat taagacctct gaggtatgca gtccattaac ttataataac
    19381 aatcactcta accactatct gacttttctt taaaaaagaa atgatttgtg atatagtaaa
    19441 tccagttaaa aaaaagtaaa ggagtagaca tgtctgcaca agataaatta attaaaccta
    19501 gtcatctgat taccatggat gacattattc gtgaagggaa tccaacttta agagctgtcg
    19561 ccaaagaagt gagcttaccc ttgtgtgatg aggatatcct attaggagaa aagatgatgc
    19621 aatttttgaa gcattctcaa gatcctgtaa tggcggaaaa acttggtctt agggccggtg
    19681 ttggtctagc agctcctcag attgatgtgt caaaacgtat catcgctgtg ctcgttccta
    19741 atcttcctga taaagaagga aatcctccta aagaagccta tagctggcaa gaagtcctgt
    19801 ataatcctaa aatcgtttct cattctgttc aagatgcagc cctttctgat ggtgaaggtt
    19861 gtttatctgt cgatcgtgtt gttgaagggt atgtggttcg ccatgctcgt gttacagtag
    19921 actactatga taaagaagga caacagcatc gcatcaaatt aaagggatac aacgctattg
    19981 tggttcaaca tgaaattgac catatcaatg gtgttttgtt ctacgatcgg atcaatgcta
    20041 aaaacccctt tgaaaccaaa gaagagctct tgattttaga ctaacaaaaa aaggcccttt
    20101 agcctttttt tgttagtcta aatagccgct aaaagagcct ctgcctgaga tagcaagttt
    20161 gcttttgtct cttttgaaat ctcaagcctt cctgttcccc aggcatcagg attcacagtt
    20221 gcttttgtaa actctcctgc tactgaagtt cggataaacg gcaatagtgc tttaaactga
    20281 tcaaatactt gatcatgccc gccatttgca actgaagaga ccgtaaccac cttaccgcca
    20341 atagcagatg ggcccgtcgg atcagacaaa tcaagagcac gagacaacca gtctagcagg
    20401 tttttaacag aacctggaat agagaagttg taaactggtg taaaaatcca gatagcatcc
    20461 gctgactgaa cagcttgacg agcgtcaaca actggtaaag gtgcattagc ttcgatatct
    20521 tgattcaaaa caggaacgtc tttccaattt aagtaagata caactgcttg atgttccaga
    20581 gctttttgtg cttgagccgc taattgatgg ttaaaagacc cttcacgaag cgagccaaca
    20641 ataaataaaa tatgtttcat ctctttgtcc tcttttttaa agatcgtttt aaagctttct
    20701 aaaagtggta tttcattgat acttcttttt gaaatttatc actatgtagt aattatatct
    20761 tctctaagaa gagccgtaaa gagatttgtt tataattgtt tgaacttttt gagaagttca
    20821 atcagacaaa gttgttcttt ttcagtcaaa acagcaaagg cttcttccac ccgtgcgacg
    20881 tgtttaggca aaacagcttc aatcaagcga gtacccttat ctgttaaggt aaccacatag
    20941 gctcttttat ccgttttgtc tttgcacttg ctaatccagc cattacgttc catattattt
    21001 agtacaacag tcatattccc cgaagtcgct aacaaagaat caatcaagtg attgattcgc
    21061 atacagcctt tagtatatag tacttcaagc acactgaact gcgtggctgt taaatctgcc
    21121 tttttaaaaa tatcagcccc aaaagcatct agcgttcgct gagctttacg aaacaccacc
    21181 atggctttca aagcggtgtt cttatctaaa tgactcattt gatttcctcg ctttatacgg
    21241 tatgtcacag tttagtatca gagagattag aaagtgatct tgtccctctt cttttatgac
    21301 tttgcatatg actaccatca tgataatcta gaaaaagtca tcaaaaagac ttaattgatt
    21361 atcttctggc atatttccta aaatacccat ctcatccatt ttctcaacga gcgttgacga
    21421 tgccccgcct cgtttacgca attccatttt agagaggaat tcgccttctt gacgagcttt
    21481 aacgatttgc ttggccacgt tttcacccag accttctaac gctataaatg gagggataag
    21541 ggtatctcct ttgatttgga attctatagc atcacttttg taaaggtcta atttgccaaa
    21601 cttaaagccg cgttctaaca tttcgttgac aatctccaag gttgtaaaga ggtcattttc
    21661 cacattggtg gcttcattat ttttacgttt tatagtaata tcttccattc ttgctttaac
    21721 agcatctaag ccaccactca tggtttttaa ttcaaaagcc ttcgcacgaa tagagaaata
    21781 agcacaataa tacataatgg gatagtgcac cttgaaataa gccacccgaa gggccatcaa
    21841 gacataagct gccgcatggg ctttagggaa catgtacttg atttttccac acgattcaat
    21901 gtaccagtcg ggcacattgt tttctcgcat ggcatcaata tagccattac gttcttcctc
    21961 agaaattttt agccataatc ccttacgcac acgctccata atggtaaagg ccattttcgg
    22021 ttgcaagcca gcgtgcatga ggtaaaccat gatgtcgtca cgacaaccga taacggtttt
    22081 tagggtcgca atgccttctt taatcaaatc ttgtgcattg ccaagccaaa catcggttcc
    22141 atgagatagt ccagacaact gcaacaattc tgcaaaagtg gtcggatgcg tctcattaac
    22201 catgccgcga acaaagttgg ttccaaattc tggaatgcct agcataccag tcggtgtccc
    22261 aatttgttcc ggggtaacgc ccaaaatctc tgtcccagaa aagagagcca taacccccgg
    22321 atcatcagca ggaatagtaa taggatcaat gcccgataaa tcctgaagtt tacgaatcat
    22381 ggtcggatca tcatgcccta ggatatcaag tttcaagacg ttttcatcaa tatcatggaa
    22441 gttaaagtga gttgtctgcc aagaagccgt tacatcatcg gctggatatt gcacgggggt
    22501 aaaatcataa acatccatgt aattaggaat aacaacaatc cccccagggt gctgcccagt
    22561 cgttcgtttc acaccagcag cacctgctgc tagacgatcc acctcagcat cccgatagaa
    22621 cttgccatag tcgcgttcat agcctttaac aaatccataa gctgtttttt ctgccacggt
    22681 acctacggtt ccagcacgaa aggcgtattc gtcaccaaaa atatctcgga catccaaatg
    22741 ggcactgggt tggtcatcac cagagaagtt caaatcaata tcgggcacct tatccccgtc
    22801 aaatccaagg aaggtctcaa agggaatatc ttggccgtct ttttgataag gggtgccaca
    22861 ttttggacaa ggcttattag gtaaatcata gcccgatccg actgaaccat ctgtgataaa
    22921 ttcagaatgt tggcaggacg ggcaaacgta gtgaggcggc ataggattaa cctcagtaat
    22981 cccgatcatg gttgccacaa aactggaccc aacagatccc ctagaaccaa ccagatagcc
    23041 tcgctcattt gaccggttaa caagcatttg tgacgctagg taaatcacgg caaagccgtt
    23101 ccccaagata gaggttagct ctttttcaat tcgcaaatcg ataatatctg gtagaggatt
    23161 accataaatt tcaaaggctt tttgataggt taattcggca accgtctctt cggccttgtc
    23221 aatatacgga gtgtaaagat cgcccttaac cacttccact tcctcaatac ggtccgcaaa
    23281 atcctgagta ttttgcacaa ccacttgata agcgaggtct tttccaagaa aggcaaactc
    23341 atccagcatt tcattggttg ttctaaagtg cgccttaggt agaggagcag gctgtgcccc
    23401 tcccccacgg ccgattgttc tattaatcat ggcaccctga ccgagactac gcacaataat
    23461 ttcacggtaa atctcttctt caggctctag ataatgcaca ttcccagtgg caagcacagg
    23521 tttcttagct cgtttcccta cttcaatgag gtcacgaatc acctgctcaa tacctgcttg
    23581 atctttgatt aattcacgga caaccaatgg ctggtaaatg gctggtggca tgatttcgat
    23641 aaaatcataa tacctagcta aatcaaccgc cgcatcaatt cctttagtca gaacggcatc
    23701 aaaaacctcg ccgtcagaac aagctgtacc tagtaacaaa ccctctctgt gagcatctaa
    23761 gacggttctt ggaatacgcg gcaccccttc aaaatatttg atattggaaa ggctgaccaa
    23821 cttaaacata tttttaagac caacctgatt ttgcacatag atagtcgcat gcttaatccg
    23881 cgcttttttg taagaatcct cagccaccaa atctgtattg agttgcaaaa gatttttgat
    23941 gccatgcttt tctctggcat ctcttagaaa aataaacaaa agacgtcctg tggcttccgc
    24001 gtcgtaattg gccatatgat ggtggtctag actcacttgg aaacgcttgg tgagcggtcc
    24061 caaaccgtga cgcttgtatt caggatacaa gtttctagca aattctaagg tatcaatcac
    24121 aggctgtgtg attttgggca agtcgtggcg ttcataattg gcgttcataa agcccacgtc
    24181 aaaactggcg ttgtgggcaa ccaagatact atctttgcaa aagtcctgaa aagcttttag
    24241 gacggtaacc aatggcttgg cgccctgcaa atgcttatcg gtaatccctg tcaattcggt
    24301 ggtaaaggca gaaagaggat gcccaggatc aatgaattca tcaaactgct ctacaatatt
    24361 tcctttaaac attttggaag ccgcaatctg aatcaggtca ttattcatag cagatagacc
    24421 tgtggtttcc acgtcaaaga ccacataggt agcttcgtgc aaatccatat caacaggatc
    24481 ataagaaata ggcaccttgt cctcaacaat attggcttct aggccaaaaa tagccttaat
    24541 tccagctttg cgagccctat ggtagccatg aggaaaactt tgcacattag catggtcggt
    24601 gatagcaacc gccttgtgtc cccacttggc tgccgtatca atcaagcttt ctactgtcgg
    24661 taaggcatcc atggtagaca tattggtgtg ggcatgaagt tcgacccgct tttgcccttc
    24721 tggcatcagg tctttgcgct catgatgtac aatttctttg acctgctgga cattcatggt
    24781 gagactcttc gtaaaaggat tggtctcaat attcccttgt acccgtaacc aagccccctt
    24841 agcaatcata tcaaatttac ggagctcctc atcgtctttg gcccattttt ggagagcaaa
    24901 cgaggaggta tagtctgtca ttttaaagtt aatgatatga cgacctgttc tagtcgtttt
    24961 acgctccaca tcaaaaacca tcccctcaaa gacaatccgg ttttcttcgg tctcaatctc
    25021 aatcattggt gtgatggtcg ctttttcaaa ccctgcctga cgcttagctg ctcgttcctt
    25081 gtagtcaaac ttaggagcag atgtggcttc ctcaactggt ggcatcatgg cctcaaggga
    25141 tttttgggct tccaaattat cctgcacagc cttttccaca agagcctgac gactggaaac
    25201 aaaatccttg gtcaaatgct cagtcatctc ctgatctgac accatatcaa tggttaaggt
    25261 gccaaagcca aaggcttcta attgcttgac caaattaggc aaatgatttt ttctaaaatg
    25321 gtcattatta acaaaacgcg gcgctgcaat aatgagtttg tcattctcat aagtcacttt
    25381 gagctttgag aaagaagatt taaaactagc actattacac ggtgcatgct caaaagcttc
    25441 ttggtaataa gcttgaagca gatcatctga ataatccacc tgagcagctt ggatatcaaa
    25501 ggttacctta atgtcagccg cctcaaaagt tcttatcaaa cgatcatgca attcacgata
    25561 agttgcaatc ggtaaaaccg ccgcgaaagc aaaatgaaat tcccacaagc gtgacaccga
    25621 atgcaccttt acctcgataa tatcagcaga tgaaaaggca cttgaacgtc tcatgtcaag
    25681 tggcatttct atctggtcca tcaatttagc gaataaatct gacataattt tctcctgatt
    25741 ttactaggct ttattttatc acaattcaag atgattttcg agttttagat ggaaagaaaa
    25801 gcagggcttt cttctgacgt tctttggcta atttagtcca agtgatagct cagctgagat
    25861 catttttttg tcaatctttt atcgccaagc gtttttggta aagcaaaagc tactctgtat
    25921 cagacaagtt cacagcaaaa agaggccgct ctaaacaggc agcctcttca tttctttttt
    25981 agtgttcttt tgttaaaatt tcaagggttt cgatgaggtt ttctgcatta acttcaatgc
    26041 tgtcacctgt tgccttgatt ttaatttcca cgataccttc agcggctttt ttaccaacag
    26101 tgacacgaat tggcaaacca atcaaatcgc tatcagagaa tttcgaaccg acgcgttcat
    26161 tacggtcatc tgtcaaaaca tcataccctt tagccatcaa gtcagcttct aacttcgccg
    26221 ttaggtcttg tgctgcttgg tctttgacgt taaccgtaat caaatgcacg tcaaacggtg
    26281 ccaattcttt agggaagtta atcccccaag cataacggta atcacctttt ggtgtcttgt
    26341 tcacaaagag acgggcatgc tgttcaatga cagcagacag gatacggcta acaccgatac
    26401 catagcatcc catgacaatt ggaacggctc tgccattttc atcaagaatc gttgctccca
    26461 tgctgtctga ataacgagtg cccaacttga agatatgacc gacttcgata ccacgcgcaa
    26521 actggagaac accatgacca tccggagaca tttccccttc tttgacttca cgaatatcta
    26581 catattcagc ctggaagtca cgtcctggat tgactcctgt cacatggaaa ccatccttgt
    26641 tagctcctgc aacggcattg gtaaggtttt gcactttgcg gtcagccaca atgcgactac
    26701 cttgtgccaa gttgacaggc ccaagtgagc caaaacctgc accaaagaaa gcacgggctt
    26761 cttcttcact agctggctct aaaaaatcag cagctagata gttttttaat ttaacggtat
    26821 tgatatggtc atttccaact agcaaagcaa caacaggttc attatctgcc acaaaaagca
    26881 aggttttgat ggtttgtgtt tcatctactg aaagaaaagc agccacttca tcaatcgttt
    26941 tgcaatgtgg tgtctcaact tctgccaagg catcttcagc agctactttt gaggacggtt
    27001 tgtattcgtt agttgccatc tcaaggttgg cagcgtagct tgattctgtt gaataagcaa
    27061 tagtatcttc acctgaaatc atccaagcag ccaattctgc cttaatctct tctaagacct
    27121 cttttggaat atcatccatt gacgcaacag acttgtcaag aaccacccag cgatcaaggt
    27181 ccgtacgagc tggtgtaatg gccataaatt cttgggaatc tttccccccc atggcaccgc
    27241 catctccaat aatccctttg aaatctagac cagctctggt aaaaatagct tcgtaagctt
    27301 gacgataatc ttcgtaggtc acatctaaat cttcatagtt gtgatggaaa ctatagccgt
    27361 ctttcatgat aaactcacgg gtacgaagca agccattacg cggacgtttt tcatcacgat
    27421 acttagactg aatttgataa aggtttaagg gcaattgctt gtaagatttg accgcatcac
    27481 gcaccaaagt cgtaaaggtt tcttcgtggg tcggacccaa gataaagtct gagttatcac
    27541 ggtttttaag cttatagagg tcctctccat aggtctcata acggcctgat tcacgccaga
    27601 gatcagctgt caaaagagct ggtgccaaca tttcaacagc accgatcttt tcaaactctt
    27661 cacgcatgat ggtcttgaat ttctcaatgg tacgatttgc cagtggtaaa taagcataga
    27721 taccagcaga aacttggcgc acataaccgg cacgcaccat aagcgcgtgg ctgataacct
    27781 gggcatcact tggcatttcg cgcaaggttg ggataagcag tttactttgt ttcatagatt
    27841 attccgtttt aatacatccc cttatcctca aacccttctg gaaacatcaa gtaagagtga
    27901 agcgggatta ttcaataatt tgaatgtgta ttcctttcat tttgagtaag acctcaatcc
    27961 ttgcaaatct tagggttgag gtctttttcg atctttaaca tgataaggtc agcttaagat
    28021 gacctatctt gattagaaaa agacgcgcat gatatcattc catgtcacag caatcatcaa
    28081 tacgaccatg atagcaaccc cagctagggt gatataggcc tctgtttctt gcttgatagg
    28141 cttgcgacga atggcttcaa tgatattcat caagattttt cccccatcaa gtgcaggaat
    28201 cggaatcagg ttaaagatcc ctaaattgat cgaaagcatt gccataagat ataagactga
    28261 ctctaagccg ttttgagcag cctgattgga catgtcatac atggcaacag gtccacctaa
    28321 tttattgaga ctaaagccag tgatcaatcc tttcaaagca ttcaaaatag taaacgcccc
    28381 actccaagct aattctagac cgcctaagag cttatcctta aatcctgttt tcagactcgc
    28441 cttaactcct atcgtgtatg tctttgcatg cttttgtggt ttcacagcca ccgtttttaa
    28501 gcgctgatgt gacttgtagg tgaccttaat ggtctgtgac gggcctagat cccgtgttgc
    28561 aaggtctaca gcctcagtga gatcattcca gctagtcacc ttataaccat taattgcgac
    28621 aatttggtca ttatctcgaa gaccagcctt agctgctgct ccattttctt gaacacggac
    28681 atgattgcta ctaaaatctg gcatcccacc ttgtaaaaag accaagagga taaaaaccac
    28741 aatccctaaa ataaaattat tcatggggcc tgcaaaattg gtgattaaac gtccgccaat
    28801 actagcattt tgatattgaa catcaagcgg agcaattctt atctcagtac cgtcttcttc
    28861 aacaatagta gcatcgtgag cgaccttata tgtcttggtt tcttctaaaa ccaagccagt
    28921 aatactcagc tgatcttcta agtcatagcc tgtaacatgc attgggagac tcgttgggtc
    28981 taacttactt tgagacaagt tgatgcgctt aacaaaacct tgctcattaa gggttaaact
    29041 tgctggagta cctgttttga tctcagtttt gtcatcaccc caaccagcca ttcgcacata
    29101 accgcccaag ggtaacatcc tcaaggtata aagagttcct ccttggtcaa catgagaaaa
    29161 aattttaggg cccattccaa tggcaaattc tcttactaga atgcctgatt ttttagcaaa
    29221 atagaaatgt ccaaattcat ggacaatcac taaaatacca aaaataataa taaaggttat
    29281 tattcctaac atagatttcc tttcagtcta ttgctttttt gagttttgtc gcgttgttgc
    29341 gactccaaac attacctctt aagattaaaa taaaccaaag agatgcatga tgggaaaaac
    29401 aaaaatcatg gaatcaaagc ggtctaaaat accaccatgt cccgggataa gcttacctga
    29461 atctttgaca ccaaagtgac gtttgagagc actttcaacc aaatcaccaa attgggcaaa
    29521 aatggaaaaa agagcgacca ataccaacat ggtcaaaaag tgatgtggcg cataaacaga
    29581 cctatcaatc accataaaga taaaagacac aaggactgca caagcgatcc ctcctaaact
    29641 accttcaatg gttttgtttg gagaaactct aggcaatagt ttgcgtctac caaactgacg
    29701 cccaatcaga tatgctccaa tatcagtggc ccaaacgata aataaggcca aaaagacctt
    29761 gtcaattcct gacaggcgag cattgatcaa atgttgaaaa ccaatcccaa cataaaaact
    29821 agttgcaatc ggaaaggccg catcatcaaa tgaataagct ctgctattta aaacagtacc
    29881 tgccaaaatg aaaaaaacca ttaagctgta aaaagcaaca ttcgcatcaa ttggtaaaaa
    29941 agtgaggtaa tggtccatcg gaactgccaa tacaaaggcg gctaacatgg caaaaacacc
    30001 ttcaaaagaa aagacttcta atcttttcat tttcagtaat tctgataccc caatcatggc
    30061 caaaacgcct acaaataatt ggaatggtag gtttcctatt atgagaaaag gtaggaaaat
    30121 agctactgct actccccccc aaacaacacg ctctttcata actatctcct tttagacctt
    30181 gccaaaacga cgttggcggc ggttataatc cgcaatggcc tttagtagct ctgccttttt
    30241 aaaatcaggc cacaagactg gtgtgaaata aaattcactg taagctgatt gccaaggcaa
    30301 gaaattgctc aaacgcagct caccactggt gcgaataatc aaatcggggt ctcggtagag
    30361 atatggcaga tggtctgtca tcaagtaatt agcaatcaaa tcctccgtaa tatctcctgg
    30421 atttaatttg gcatctaaga catcttgagc aataaagcga acagcactgg taatctcagc
    30481 acgtcctcca taattgagag caaaattcaa aattaaaccc gtattacgtt ttgttttgtc
    30541 gatggctgca tttagcgctg ccaaggtatc ttcaggtaaa cgactagtct ctccaatcat
    30601 ttgaatcttt acattgttct catgaagcac aggcacatat ttgtcaaaga aggttactgg
    30661 taaattcatg ataaaagaca cctcatcttg gggtctggac cagttttctg tcgaaaaggc
    30721 atagactgtc agaactttaa cccccaactc agatgcagta atcgttactt cttgtaaagc
    30781 atccatccca gctttatgcc caaacactct aggttttagt ctttttttgg cccaacgtcc
    30841 attaccatcc atgataattc caatatgctt tgggatactc cccaaaactt tttttgttga
    30901 tttcgctttt aatccaaaca tgttttttcc ttattgataa gcatacttat ctcatatttt
    30961 atcatatttc acgccttttg gcttgttttt tatcaattag atcttatctt cacaaaatgt
    31021 tcacctatcc tctgatagat gtgtcagctt ttcatgaacc tgttagcatc agaataactg
    31081 tttcagtcca gggatcaaaa caaaaaagtt tggcatattt catccaaact ttccccgcct
    31141 taatggcttt caatggcact gtcagtgtca gtgctatcta ctgtctcaac agcaggctca
    31201 ttaacaacac tggtttcttc agtttcaacc agtgtcgttt ctgtggtagc ttttgttaca
    31261 atacgcttaa tagctgatag ctcaaatgtc aaaaagacgc catccacatc taacacaatc
    31321 tttttagctg ttgtatcgac ttcgtcaaca atcgcaaaca tgccaccaat cgttacgact
    31381 tcgtctcctt tttcaatagc gtttaactga ttttggcgtt cttgcgcttg ttttttttgt
    31441 tgacgttgca taaaccaaat caatccaagc atcactacaa acattaaaat tgttggaaat
    31501 cccataatgt ctccttttta ttctataaaa gtcatgtctt actatatcaa aaatcaagcg
    31561 gtatagcaag actagacgtt acctgatgtc ttctttaaac gagacgctaa gcgcagtgct
    31621 ttactcacga gtcaaaaaag ctaagatgtc atctggtgtc aaacttgaat cacatacagc
    31681 cctttggtgc tgatcgtaac taaccagcaa agctggaact gtcactaatt ggtagttctc
    31741 acgaaaggca gcaagctcag cagcatcagc agcgttttcg ctatccacaa aatagacttc
    31801 tttttgatta tctgttgcta cttgtgccaa cttgggagca aagcggcgac aataaggaca
    31861 gctcgaacgt cctaaaaaga caatcatgtc tttgccacta gcgatagctg atgtgacttc
    31921 tgcaacactc gacggtataa aattcgcaac gatttcttca aatgtcatgg atgtctcctt
    31981 ctcttttggt ctcatgatac actaaagtag caattttctc aatcacaagg tcttttcaca
    32041 gctcagagct tttatagccg tcaaaaagaa tccgcaaacg gcaatctttt tgtctctatt
    32101 aacaccaccc taatcttttt ggcgcttcat caacaggcta atagccaata aaagcagagc
    32161 tactccggct gctaataagc cttttgaggg ggcttcaccc gtttttggga gcttttggtt
    32221 tgttttagct ctttttggcc tagtcattaa tgatttgtct aggtcttttg agccatctgg
    32281 tgttttggtt tgatgattat ctgtctgact cttttgctga gagggattag ccgtttttga
    32341 ggatactttg aggaccaggg cagttaggcc atcaatagtc aagccttctt tggtaaactg
    32401 gactccctta ggcttagcaa tggcagtaac accagcttgc tcagcatcag caagcacttg
    32461 ggctcttagc aaatagcggt aggcttgagg taaaactacc ttgcgggtct tgttgtctgc
    32521 attgacaaag acagcatagc gatctccatt tgatgccacc gtttggtaac ccatgatgag
    32581 gtcctcttgt tgaataccat cttgtcctgc ttgggtgatc aaggtcacat cccgatctac
    32641 ctcagctttg gttgcttttg taaaggcatc tgttgagcga cgcaacgcaa ttagtccctg
    32701 tgtataggct tttgtttggt tgctaatcgg gtgagctatg gaatctgttg cctttgccca
    32761 gtcaaaatga ttgaccgcat cagacgaatc ataagaatcg tggatgaagt aagggtattg
    32821 cgctacagca tcaatcagag tcgccttatt tggcaccttg tcatcagaca cctttgtctt
    32881 gtagtcggga tttagaagct gcttggttcg tccatattcc tgaccagaat ggataaaggc
    32941 agtcccttga gcagttaaaa tcatggtatt tcctagacga atacgcttgt gaatctcttc
    33001 ttcagccact ttaggatcct tattgatgga tttggcaatg acatcatgta aggtcaggtt
    33061 gtcatgggct gcaatatact gcactacatc tccaggggca tctgcttcaa aattactagg
    33121 ctgtgctttg atcgttttga acagtccttc tagatttttt gcgccaccag taataaaggc
    33181 tgctgtgcct tcatttggaa aacctgattt gagggtattt ctgatatcat cagagaaaac
    33241 accgaccgta ttggttgctt tcatccaatc ttgatctgcc gcaatttctt ttttcccctc
    33301 atcaccttgg taggtacgcc agccttcgcc aatcataatg gtatttggat taatggcttt
    33361 ggctgcctta aaggcttgct caatagctgc cgcatcatgg tcacccatca tgtcgaaacg
    33421 aaaaccatct accttgaatt cacgagtcag ataagtaatc gaatccacca agatacgacg
    33481 gctcatggca tgtgtcgttc ctagacgacc tccgccaaaa ctctctctag ctgtgccatc
    33541 agcattcata aaatgatagt agttgggttc caaatcttca aagagatagg ttctagccgt
    33601 gtggttataa accacatcaa aaataacacc cataccacgt ttgtgaatct cattgacaag
    33661 gtttttaagc tctgcgatac gtaaagcagg gtcgttagga tttgccgaat acatgccaga
    33721 aagggcaaag tagtgttgtg ggtcataacc ccagttgtaa ttattatctg aagacgtgta
    33781 ggctgttgag cggctcttgt ccagctcatt ggcataaaaa taactcaaaa ccggtagcaa
    33841 ttgaacgtgg gtaaccccca agtctttgag atagtctagc tgttcaacga aagctgaaaa
    33901 agtcccaaaa gggtgtgtta acttgccttc tagagcctta tctgacgtaa aatctcgcac
    33961 atgtgcttca tagataatag cgtcttcacg ctttttaaag ttgttaattt tggcaaaatc
    34021 aaggcctgct ggtcctagtt tgcttggatc aataaaggca gcttttgctg ttttgatgtc
    34081 atcagtagca gtcgcattat tccaggcagc gagagatttg gcgtaaggat ccaaaaccat
    34141 gactttttcc tgaccgcgcg tgatttcata aaggtaatag tagcctgtgt aatcactaat
    34201 gcccttgata ctatcagaag tcagatgagc tctccaaaca cccttgtccg acttggtcaa
    34261 attagcttga ccaagaacct ttgtctgatc ttgtttatca taaacgacaa ccttaacagt
    34321 atcagcactt ggagaccata gcgctaaatc aacagaacca tccttagcta gggtagctcc
    34381 aagttcacca tcgtaagcat agagtttatc ttttaattgc caggattggc gagcgacttg
    34441 gctaacttct ccaaatgtaa ccgtgtagac tgcaccttgt gccttaaaat caccctttaa
    34501 tgtcattaca gacttatcct tgtcaagtgt caactcatca attgcaacag ttttccctgc
    34561 tttgtcagtg atcttgatgt tttgtttcac cgcatcttca tcaagcccat ctaaggtcgt
    34621 aaaaatggct ttaatctcat ttggcgtggt ttgttcagct cctttgagac taacctgatc
    34681 aatataataa ggattgttgt aaacttttgg gtcagtgtct ttgacaaaaa cctgagtatg
    34741 attgtctaac tctttaaaca gataatcttt tggttgcact ttaatagcat ctcctgtctt
    34801 acttttatca aggattaaaa atccgatttc gttagctcct tcttttaagg ggacatcaac
    34861 ataagctcca taaggccctt tatgtgacaa gtcaagtcca tttggccagt cggtcgttgg
    34921 ggttttgaca tctttaaagg tccagacagc taagttatcg tagtgtcccg attgattgtg
    34981 gtagttgatt cgaaggtaac cttttttcaa aggtcgataa gcgtgcgcat ggtaattctc
    35041 gtctatccaa acttcattca tttttggcgt gagaagcgag atgtgctggt cctttgaaag
    35101 attctctcca gctttattat taatgagata agacacttgc tggcggtgtt tagctgctag
    35161 tggcacatct agataatagc catagtcatc ttttttcgcc tttgtcatgg tgatagcacc
    35221 atttggccaa tcctttgaag gttgatccac atctccccac acccaaagtc ccaagcttcc
    35281 tagcgtctca ccagctggca atgttttaaa atgcatacgc aaatgatgct cagcaatact
    35341 atcaggatta gttgacgagc tgtctaaaac tggttttgcc tccttgctag acgattgaaa
    35401 accatcacca gatttagcat tgccatctcc ttgttgagct tcatcgcgag ctagtccaac
    35461 aatggtttta gcagcaactt gatgtgttaa gatactaggg gtgcacccta acatgacagt
    35521 cccagttgca gcgattacaa aacctatccc ccgctttttt aacagatact gatagcgctt
    35581 tgatccttgg ttgactttct ttttcataag acctccattt agtataacat tcaaacaaga
    35641 ctatcttatc acattgcgca agcgcttgca agacgtgccg cacttcaact tagaacacag
    35701 ctcaaacaat gactatcacc ccttaatagg atctcaagaa tcaaacagcc aaaacgagtt
    35761 tccgctcgct tggctgttgg gtaaactcaa atcacataca actgctaggc cttcagtttg
    35821 agacaaaagg catcccaagg ttgtaagtgc ttggtctcta ataccgtgtc cacatctgta
    35881 ttggcgatga tcacttgtgc acctgctaag tctgtggcaa agacttgctc ctcatcagac
    35941 acattgacaa caatcacata cgtctcttct ccaagctgac gctgataagc aaacacttta
    36001 tcagctgttg gcaagaggtg ataatccgct tcaactagcc agtcttgctc cttacgcaag
    36061 gcaatcaatt tttggtaggt gtaaaaaata gagtctggat cagcaagggc atcggccaca
    36121 ttgatgtctt ggtagttggg gttgaccggc aaccaagtct cttgggcttt agaaaagcca
    36181 gcatgtgtgt ccttagacca ctgcatcggc gttctagcat tgtctcgtcc taccttacgg
    36241 atgctatcca tcacacgcgc agctgacact ccatttccca tagcttcctt agcatagttg
    36301 agtgactcaa tatcatcaac ctcagttaag tctttaaaag gatagttggt catgccaatc
    36361 tcttctcctt ggtaaatgta aggggttcct cgcatcaaat gcagtaaaat agctaaagcc
    36421 ttggctgatt tttctcggta agtgctgtca ttgccccaaa tggataagac ccgtggcaag
    36481 tcatggttat tccaaaaaag cgaattccag ccttctccca actttaattc tgtctgccac
    36541 ttgctgaaaa tagctttcag agcaggcacg tctaattctt tggcataatc ccacttggga
    36601 gcgtcaggtt tatgttgaag acccacatgc tcaaattgga agaccatgga taactctttg
    36661 ttttcagggc gagaatactg gcgagcaatt tcaggcgttg ctccccaagt ctcaccgaca
    36721 gtcatcacgt catggttgcc aaaggttgct tgattcattt ctttgaggta atcgtgtaag
    36781 cgcggcccgt tacccgtgat ttcagaatct ggaaccttcc caatcaggtc aatcacgtcc
    36841 atacgaaaac caccgatgcc tttagcaatc cagaaattca tcatatcgta aattttatga
    36901 cgtaaagctt cattctccca gttgagatct ggctgacgtt tgctaaaaag gtgcaaataa
    36961 tattgacctg atgcattatc atattcccaa gctgagccac taaaaataga agtcaaatcg
    37021 ttaggttcat ctcgccaaat ataaaaatca cgctcaggac tattagggtt ttccctagct
    37081 tcaacaaacc aagcatgctc atcagacgta tggttgacca ccaagtccat gataatctta
    37141 atgcctcgct cattagctgc tgctaagagc tcatccatat ctgccatgtc tccaaaaaca
    37201 tcagcaatcg cttcatagtc agagatgtca tagccattgt catccatggg cgactggtaa
    37261 acaggagata accaaatggc tgtaatgcca agtttttgca agtagtccag ctgactggta
    37321 atgcctttta aatcaccaat accattgcca ttggtgtctt taaaggattt cgggtaaatc
    37381 tgataaatcg tagctttatg ccaccagtgt ttcttcatta ttcttctcct attaatcatt
    37441 cattcatctt ttattttaac gttttttctc cttttgtgca atcgtttgcg caaatgacat
    37501 gataaaaagg ctggaaccca acctttttat gaatatcgct tataccttaa cgaatagctt
    37561 gttcggtatc tctgtcaaag aaatgcccct tagccacatt aaaggtcaag ctaacttgct
    37621 cccctggact atggaaatca cgcgcatcta cccgagaagc aaactcagtt tgtccaagct
    37681 tgacatagag catcgtctca gatcccagta actcagaaac caaaacttct gctgtgacag
    37741 ttgcacttgg ataagtatca tgcacgattt gtctactaga aatgtcttct ggacgaatac
    37801 caaaagtgac ttttttcccc ttgtaaccag cagcttcaag catttttgct tgaccttcag
    37861 gaatagcaat gtcaagacca tcttcactca caatgcggcc atctttaact tccacttcaa
    37921 agaagttcat ggcagggctt ccgataaaac cggcaacgaa tttattagct ggaaggttgt
    37981 acaattcttg tggtgaacct acttgctcaa ttttaccaat cgttccatta ccttgagggt
    38041 ttttagtggc actcatgata acgatacggt ctgccaaggt catggcttct gtctggtcat
    38101 gggtaacgta aatagttgtt gagccaatcc tacgatgaat ctttgcgatt tcagcacgca
    38161 tggagacacg aagcttcgca tccaagtttg acaaaggttc atccatcaag aataccttag
    38221 catcacggac aatagcacgc cccatggcaa cacgttggcg ttgtccacca gacaggtcag
    38281 caggtttacg ctctaaaaat tcggtcaaac caaggatctg cgcagcttcc ttgacacgac
    38341 ggtcaatatc atcttttttg tacttacgta atttcaaacc aaaggccatg ttatcataca
    38401 cggtcatgtg tgggtaaagg gcgtagtttt gaaagaccat ggcaatatca cggtctttag
    38461 gagacttgtc attcaccact tcgccaccga tttttaactc tccttcagaa atgtcctcaa
    38521 gacctgcaat catacgaaga gtagtcgatt taccacatcc tgaaggtcca acaaagacga
    38581 taaattcttt atctttgatg tccaagtcaa aatcttcaac ggcataatga gtagtattgg
    38641 ggtatttttt atagatgtga tttagattta attcaaccat gtgtaactcc tatttgaata
    38701 gcaaacgttc tagctgactg caaagctaga aaccgctgat atcttttata tgatgctttt
    38761 attataacaa aaatagcgct ttcaaaacag agacaaagcg accaaacttc tttgggcaac
    38821 ttgcacaata gcagggctag tcaagtcgta aagacccata aaacaagaaa accatgtaaa
    38881 cacaggccgg tcacaggagc caaaacaagc tgaacgatct atcatcctcc ttatcagcta
    38941 cagtcaaggc agcaaaaaag aaagccctgt ggctttccta atatttcaac aaaaagagat
    39001 gagcaaaggc taaatcatcc aattgcttca agtgtagtcc tgattgctga gcaaatttat
    39061 caagcttata ttgcaacgaa ttgcgatgaa tgtagaggcg ctgcgctgtc tgcaccagat
    39121 tgccgtgttc tgaccatagc gcgtgaacca catcggccat atcactttga ggacttagga
    39181 attggtgaaa ctgacgcgtc aatgccaaaa aagtgtggtg cgacagcaaa gaccacagca
    39241 tcagtcctga aaatgttaat aattttctgc ctgattgttg ccttaaatag gccgttaaca
    39301 gctgacattc ctcctcaaaa cactctctca atgtacccgc agctacttga taccaggcat
    39361 ttccaacaaa catggttaag gccaaaccaa aatcactttc tagcgttggc aggagatctt
    39421 caagccagcg caagaccttt attgagattg cttgtcggca taaaaatgcc gtctgagttg
    39481 cgctgatagg caaaatgacc tcaagccctg caatcatctg ttggagcaac tcaactaagt
    39541 cagctggtaa agcctgctga tgattgaggt aaatgaactg agaagtctca tacagctgag
    39601 ggggattgcc ctgatgatca agcaaatacc gctgccaagg tgaccctagc ggctgcaaga
    39661 cctcacactg acccagtccc acctcaagta ataagcgctc tttttcggat aaacatgatt
    39721 tgggaaaatg cacatattgg tccccttctt tgacactcac ccactcttta tctcctaacg
    39781 gatgagggcc tacttgcatc tctggaaaat agtcttttag ctccatagcc attcctttca
    39841 tgacggtctt taaaccatta taacacatga ctctttatca cacagttcgg tttgttgtca
    39901 gcatgatttt gtattttctg actttctaat cattgaagct aaataatggt tattcatttt
    39961 tagcaagaac attcaatcaa atagctattt atcggaagat taatttattt ttatactaaa
    40021 ataggtattg tttctctttt ttcattatca tgacattatc attaagatat catttaaaaa
    40081 caattattag gtttttgttt gtatctataa aattattatg ttattctaat aatggggatt
    40141 gaaacttaac ttttaggagg tttctatgaa aaattactta tcttttggga tgtttgcact
    40201 gctgtttgca ttaacatttg gaacagtcaa gcctgtccaa gctattgctg ggtatgaatg
    40261 gctgctagac cgtccatctg tcaacaacag ccaattagtt gttagcgttg ctggtactgt
    40321 tgaggggacg aatcaagaaa ttagccttaa attttttgaa attgacctaa catcacgacc
    40381 tgctcatgga ggaaagacag agcaaggctt acgtccaaaa tcaaaaatgc catataaact
    40441 ggaaaaagct gacttattaa aggctattca agaacaattg atcgctaacg ttcacagtaa
    40501 cgacggctac tttgaggtca ttgattttgc aagcgatgca accattactg atcgaaacgg
    40561 caaggtctac tttgctgaca aagatgattc ggtaaccttg ccgacccaac ctgtccaaga
    40621 atttttgcta agtgggcatg tgcgcgttaa accgtatcaa cctaaagccg ttcacaactc
    40681 tgctgaacgc gttaacgtca actatgaagt gagctttgtc tccgaaacag gagatttaga
    40741 ctttacaccg ttgttaagaa accaatacca tttgaccaca ctggcagttg gtgactctct
    40801 ttcatcacaa gagttagcag caattgccca atttatccta tcaaaaaaac atccagatta
    40861 tatcattaca aaacgtgact cctcaatcgt cactcatgac aatgacattt tccgtacgat
    40921 tttaccaatg gatcaagagt ttacttacca tatcaaagac cgggaacaag cttataaggc
    40981 caattctaaa acaggtattg aagaaaaaac gaacaacact gaccttattt ctgagaaata
    41041 ttacgtcctt aaaaaagggg aaaagccgta tgatcccttt gatcgcagtc acttgaaact
    41101 gttcaccatc aattacgttg atgtcaacac caacaaattg ctaaaaagcg agcagctctt
    41161 aacagctagc gaacgtaact tagacttcag agatttatac gatcctcgtg ataaggctaa
    41221 actactctac aacaatctcg atgcttttgg tattatggac tataccttaa ctggaaaagt
    41281 cgaggataat cacgatgaca ccaaccgtat cataaccgtt tatatgggca agcgacacga
    41341 aggagagaat gctagctatc atttagctta tgataaagat cgttataccg aagaagaacg
    41401 agaagtttac agctacctgc gttatacagg gacacctata cctgataacc ctaaagacaa
    41461 ataaccacga tcttctaaaa cgatgagatt aactgacaaa aaaagcaagc aacacgctat
    41521 caacagttgc ttgctttttt ctaatctctt agttgtagag actagtgaca tttcgtgtct
    41581 aaaataatcg taactggtcc atcattgatg agactaacct gcatatctgc cccaaaaacg
    41641 ccacgctcaa ctggcacaaa ctctgccaat tgttcattaa agctatcata caactgccta
    41701 gccaaatctg gcttagcagc accagtaaag gcaggacggt ttcccttttt ggtgtcagca
    41761 taaagggtaa attgcgacac agataagata ctgcccttga tgtcttggat agactgattc
    41821 atcttgccat cagcatctga aaaaatgcgc atgttgacta tttttcgcac agcgtaagcc
    41881 aaatcttctg cattatcatc tggtcccaca cctactaaca acaacaatcc ttgattaata
    41941 gcgccagcaa ttttcccatc aatagaaaca gaggcctctt tgacccgttg caagacaagt
    42001 ttcatgtttt tatcctttct tagccattgg tccgcttcac actataaaca tctggaactg
    42061 ccttgatttt ttcgacaaca gtggtcagat gcgtcagatt tggaatgcca aagctcacgt
    42121 gaatattagc aaacttcatg tctttggtcg gctgagcatt gactgtcgat atgctcttgg
    42181 ttgagtttga taaaatttgg agcacatcat tgagcaggcc actacgattg agcccataga
    42241 tgtcaatttc agcctgataa tctttactcg aattgtccaa atcccactcg acctcaatca
    42301 agcgttcttg gtagccatct tgactcttaa tgttatgaca gtccgatctg tgaatcgcaa
    42361 tgccacgccc tttggtaatg tagccgtcaa taggatcacc aggtacagga ttacaacact
    42421 tggcaatccg catcaagagg cctgatgctc cttggataat gactccattt tcactgcgaa
    42481 ccttgagcac atctttgttt tcgtgtttga cctcaccgcc cttaaccaat tcttcagctt
    42541 ctgctttagc cttggccctt tcttcttcac ggcgctcttt ttcggttaac ttgttaaaga
    42601 cactgatagg actaatgtca ccaaacccaa cggctgcata gagcgattct tcgctcttca
    42661 cactgacttt tggaaggatc gcttcaatgc gttttttgtc aaggtattta ttggcaacgt
    42721 agccctgctc ttgaaaataa gacaccaaca aatcacggcc tttattcact gacaattcct
    42781 tgtcttgatt tttaaagaac tgacgaattt tgttgcgagc cttattggtt ttgaccagtt
    42841 ttacccagtc tcgactaggg ccaaaggaat tggcattggt gatgatttca accacatcgc
    42901 ctgtttttaa cttggcagtg agaggaacca tacgtccatt gactttggca cctgttgctt
    42961 tttcaccgat ttgcgtatgg atcgcataag caaaatcaat aggacctgat tcttttggca
    43021 actcctgaac ggcccctgtc ggtgtaaaga cataaatccg ttcagaaaaa atgtcttctt
    43081 tgaccgaatc cacaaagtcc actgcatcac catttgaggc atcttgcaat tctaccagct
    43141 ctttgatcca gttcatgcca acggcttgct cagcctgatt gaccttacca cgcacgcctt
    43201 ttttataagc ccagtgagca gcaaccccgt actcagccac ttgatgcatg tccttagttc
    43261 tgatttgaat ctcaataggt ccttttggtc catacacggt ggtatgaatc gactggtagc
    43321 cattagcttt aggagctgca atataatcct tgaagcggcc tggcatggga cgccaaagct
    43381 catgaatata gccaaccata gcataaacat cgctctgcgt ttccatgaca caacggatag
    43441 caatcaaatc aaaaatctga tcgaaacgtt tctttttgtc ccgcattttc cgataaatgg
    43501 aataaatgtg ttttggtcga ccatacacat ctccaaacaa gccttgttgt gtcgtatagg
    43561 ttttgacctt actgacaata gcctctacca aagcttcacg ctcgcgacgt ttttctttca
    43621 tcatatggga aattttgtaa aattcggttt cattgaggta acgaaaagac aaatcttcta
    43681 gttcccattt gatgcgacta atccccaaac gatgcgccaa gggggcatag atttccatgg
    43741 tttcgcgcga aatacgctct tgtttgtcct tgcgcaaatg tttgagggtg cgcatattat
    43801 gcaggcggtc agccaatttc accaaaatca cgcgaatatc tttggacata gccatcagca
    43861 ttttgcgatg gttttcggcg agttgctcct catgagattt gtactcaact ttacctaact
    43921 tggtgacacc atcaacgata tcacgagcat cttggccaaa gtctgcttcg atctcatcta
    43981 aggtaatatc cgtatcttct acgacatcat gtaaaaagcc acaggcaact gtcacagcat
    44041 ccagatgcaa atcagccaga atccccgcca cctgaatcgg atggacgata taaggttcgc
    44101 ctgactttct cacttggtag aaatgggccg ctgttgcata tgctaaagcc tttgccacaa
    44161 aagccacatc agccttggtc atataggtgg ccgctaaggc aatgacttct tctcctgtta
    44221 cgttcattat ttttgccatt tcgttcctca tctagcattt cttttcccta ttttaacact
    44281 ttacacacaa aagcaaaagg cagaatctgc taagaaagcg cttagtgtga ccttttctta
    44341 gaaaacggtt agtgagctgc ttttgatatc ttttgggatc tctcaggcgt gagcatgata
    44401 ccaaaggcct gctcccgacc aaaaatagag agaaccaagg ggctctctct attatgtttg
    44461 cttatcagta aggcctctca atttagagga ttagttgttt tctttacgtt ttgtaacggc
    44521 taggacacca gctgttgtca tcactgctac tgctgctgct gtaaagaatg ggttggcttg
    44581 ctcaccagtt gctggtagac gtctgtggtt gttggctaca ggtgtcttag ccatattgcc
    44641 attgcgacgt tctggcgttt ggttagcttc tttgtcagca ggtttttctg gagctggagt
    44701 tacctctttg ctcttttctg gagctttttc gcctggttgc tctggcattt ctggcgttgg
    44761 tgtcacttct gggctctttt ctg
//
LOCUS       DAUCXI010000014        41768 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.014, whole genome shotgun sequence.
ACCESSION   DAUCXI010000014 DAUCXI010000000
VERSION     DAUCXI010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41768
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.014"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..913)
                     /locus_tag="VGY43_000752"
     CDS             complement(<1..913)
                     /locus_tag="VGY43_000752"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ4301959.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGLNITLPYKREVMRYIDNLDRVAEIT
                     GSVNNIYKSGNIITGTNTDWKGIYNTLVFFNISHITKCCVLGTGGTARAAIFTLQKLQ
                     ISPTVVYREPISENTRSLIKSFPDLKYITYKELADQQILNDIEIIINTTPVGMINYEE
                     SLPINFDHLDNVNYKDKYFMDVVFNPLHTKLHEYFGKRGAKIIDGLWVLIFQGIEAFS
                     LWSDKINGGKYFFSKDDVVLIHTFLEGK"
     gene            complement(982..1053)
                     /gene="shp3"
                     /locus_tag="VGY43_000753"
     CDS             complement(982..1053)
                     /gene="shp3"
                     /locus_tag="VGY43_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEQ4301960.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            1133..1984
                     /gene="rgg3"
                     /locus_tag="VGY43_000754"
     CDS             1133..1984
                     /gene="rgg3"
                     /locus_tag="VGY43_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HEQ4301961.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNPYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     TLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            complement(2237..5776)
                     /gene="smc"
                     /locus_tag="VGY43_000755"
     CDS             complement(2237..5776)
                     /gene="smc"
                     /locus_tag="VGY43_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEQ4301962.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFDKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVVLDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQRTEQLLHIDQQLCDVKQQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKRVQELERDYQLNQERLFDLLDQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKLGGIIGAVSEHLSFDSDYQTALEIALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLVRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGANRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVAALQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKSALTCDIDDIKENKDLVR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAITQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKMT
                     FEAIRKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(5777..6469)
                     /locus_tag="VGY43_000756"
     CDS             complement(5777..6469)
                     /locus_tag="VGY43_000756"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEQ4301963.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKD
                     YKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            complement(6923..7732)
                     /locus_tag="VGY43_000757"
     CDS             complement(6923..7732)
                     /locus_tag="VGY43_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ4301964.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDIYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            complement(7736..9088)
                     /gene="vicK"
                     /locus_tag="VGY43_000758"
     CDS             complement(7736..9088)
                     /gene="vicK"
                     /locus_tag="VGY43_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEQ4301965.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADIELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            complement(9081..9791)
                     /locus_tag="VGY43_000759"
     CDS             complement(9081..9791)
                     /locus_tag="VGY43_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4301966.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            complement(9953..10987)
                     /locus_tag="VGY43_000760"
     CDS             complement(9953..10987)
                     /locus_tag="VGY43_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ4301967.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     PIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYIISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFILDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISRHDP
                     QFRRDTLKGFRTPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            complement(11043..12290)
                     /locus_tag="VGY43_000761"
     CDS             complement(11043..12290)
                     /locus_tag="VGY43_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEQ4301968.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDQTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDGELLKKADFAVL
                     SSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLKDNGKINREVLLNKIPKQWLS"
     gene            complement(12247..13395)
                     /locus_tag="VGY43_000762"
     CDS             complement(12247..13395)
                     /locus_tag="VGY43_000762"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEQ4301969.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNAVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREHGFT
                     KEYLNHWTLRSHQKASYCQEQALLADLILDLPGASDQGIRPRLSSKVLSKVPPILGED
                     HVISAANACLTHDAAAFLQLSSQPSAFKLIDVVEVAGDPQRSPLMVIKASQVLLEKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGHYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            complement(13790..13939)
                     /locus_tag="VGY43_000763"
     CDS             complement(13790..13939)
                     /locus_tag="VGY43_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HEQ4301970.1"
                     /translation="MQLLDNIYGTLRSFAFMRPVKSSNDTSLADALQADTDMAFILVR
                     GINYQ"
     gene            complement(14140..14925)
                     /locus_tag="VGY43_000764"
     CDS             complement(14140..14925)
                     /locus_tag="VGY43_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4301971.1"
                     /translation="MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVVSLLVLALSLKLWKWGLDAYESAGS"
     gene            complement(14927..15745)
                     /locus_tag="VGY43_000765"
     CDS             complement(14927..15745)
                     /locus_tag="VGY43_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEQ4301972.1"
                     /translation="MWSFWKRYSPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLVVLSGIKVMAGLSILQVLASSCLYLVSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKMVSIVLSFLPL
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            complement(15747..16739)
                     /locus_tag="VGY43_000766"
     CDS             complement(15747..16739)
                     /locus_tag="VGY43_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ4301973.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEAVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVTQLKQTFGKMKSLSFELEAGQEEVVSQFLGLPDIT
                     VERHELTLEIQYDSSRYQTADIIQKTIADFAVRDLKMTDVDIEDIVRRFYRKEL"
     gene            complement(16880..18823)
                     /gene="thrS"
                     /locus_tag="VGY43_000767"
     CDS             complement(16880..18823)
                     /gene="thrS"
                     /locus_tag="VGY43_000767"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEQ4301974.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLHLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQVTVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTE
                     SVEEFVENILADIARKSRPDAQA"
     gene            complement(19245..20579)
                     /locus_tag="VGY43_000768"
     CDS             complement(19245..20579)
                     /locus_tag="VGY43_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ4301975.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGDGPYLQDLKHFAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLR
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            complement(20581..21579)
                     /locus_tag="VGY43_000769"
     CDS             complement(20581..21579)
                     /locus_tag="VGY43_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEQ4301976.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADPKKEAAFRRYFDIKEG
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDVRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            complement(21709..22710)
                     /gene="ccpA"
                     /locus_tag="VGY43_000770"
     CDS             complement(21709..22710)
                     /gene="ccpA"
                     /locus_tag="VGY43_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEQ4301977.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            22884..23969
                     /locus_tag="VGY43_000771"
     CDS             22884..23969
                     /locus_tag="VGY43_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEQ4301978.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYAEFD
                     HLNVNKFHGLQTIFSGQFNNLTPYVQGMRLIKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVAVGQPDQFKIDIYNLCLEAQLVAIDFIKPGVTAAQVDAVARQ
                     VIEKSGYGEYFNHRLGHGIGMDVHEFPSIMASNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            24018..24683
                     /locus_tag="VGY43_000772"
     CDS             24018..24683
                     /locus_tag="VGY43_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEQ4301979.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SVGLEGWRFVVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            24694..25071
                     /locus_tag="VGY43_000773"
     CDS             24694..25071
                     /locus_tag="VGY43_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ4301980.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFKENYRKDFPDSQFTLVYL
                     TLEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            25216..26142
                     /locus_tag="VGY43_000774"
     CDS             25216..26142
                     /locus_tag="VGY43_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ4301981.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDD
                     GSKDNTLGILRELATRFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPVMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            26351..27034
                     /locus_tag="VGY43_000775"
     CDS             26351..27034
                     /locus_tag="VGY43_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEQ4301982.1"
                     /translation="MEWIKLIGIVIIVLGFILKCDAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQSLTVGRLLTLYLII
                     RELAGLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDAEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            27034..27960
                     /locus_tag="VGY43_000776"
     CDS             27034..27960
                     /locus_tag="VGY43_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 family protein"
                     /protein_id="HEQ4301983.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEEIAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIISHIALMYLLAYY"
     gene            28010..28657
                     /gene="pcp"
                     /locus_tag="VGY43_000777"
     CDS             28010..28657
                     /gene="pcp"
                     /locus_tag="VGY43_000777"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEQ4301984.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(28774..29493)
                     /locus_tag="VGY43_000778"
     CDS             complement(28774..29493)
                     /locus_tag="VGY43_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HEQ4301985.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNSHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(29499..29966)
                     /gene="smpB"
                     /locus_tag="VGY43_000779"
     CDS             complement(29499..29966)
                     /gene="smpB"
                     /locus_tag="VGY43_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEQ4301986.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLENELKGSG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            complement(29969..32302)
                     /gene="rnr"
                     /locus_tag="VGY43_000780"
     CDS             complement(29969..32302)
                     /gene="rnr"
                     /locus_tag="VGY43_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEQ4301987.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGAKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSSLDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNVDRLTQSALMEINPQGYVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVALHRILETMRSKRGALNFDTQEAKVIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKAEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMMLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYSQPSQEKRDHFTQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVASVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKMSDKASRRDRRKSSKSSKGIK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            complement(32396..32632)
                     /gene="secG"
                     /locus_tag="VGY43_000781"
     CDS             complement(32396..32632)
                     /gene="secG"
                     /locus_tag="VGY43_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEQ4301988.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            complement(32678..32824)
                     /gene="rpmG"
                     /locus_tag="VGY43_000782"
     CDS             complement(32678..32824)
                     /gene="rpmG"
                     /locus_tag="VGY43_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEQ4301989.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            complement(32821..34014)
                     /locus_tag="VGY43_000783"
     CDS             complement(32821..34014)
                     /locus_tag="VGY43_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEQ4301990.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPTELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCSLMTAVYVKEEFKPIRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVTPILSLYIRHLGQIHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVVAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            complement(34136..35638)
                     /locus_tag="VGY43_000784"
     CDS             complement(34136..35638)
                     /locus_tag="VGY43_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HEQ4301991.1"
                     /translation="MTTMTIAKGNQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISELGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DHASDYSSHYGNVTKQSVGAIQRSLLTLEQEGAEQFFGEPALEVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYELLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLAQLGNRIQHALRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSDI
                     ESQQLVQSSPFASKYSQSIDRDSAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKA
                     QAATKKASRRSVGRPRKTVVEKATDAFISTTVKTIGRELVRGLLGSLRKR"
     gene            complement(35828..36421)
                     /locus_tag="VGY43_000785"
     CDS             complement(35828..36421)
                     /locus_tag="VGY43_000785"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEQ4301992.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKTDGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLA
                     QSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNSGDIAALIKQVQSALLSLANPR"
     gene            complement(36418..37245)
                     /gene="mutM"
                     /locus_tag="VGY43_000786"
     CDS             complement(36418..37245)
                     /gene="mutM"
                     /locus_tag="VGY43_000786"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEQ4301993.1"
                     /translation="MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKEIFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIKKGGS
                     TVRTYRNALGADGTMQDYLQVYGQTGKSCPRCGQDIVKLKVGGRGTHICPKCQKKRP"
     gene            complement(37417..38283)
                     /gene="rgg2"
                     /locus_tag="VGY43_000787"
     CDS             complement(37417..38283)
                     /gene="rgg2"
                     /locus_tag="VGY43_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HEQ4301994.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKMLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            38372..38440
                     /gene="shp2"
                     /locus_tag="VGY43_000788"
     CDS             38372..38440
                     /gene="shp2"
                     /locus_tag="VGY43_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HEQ4301995.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            39354..39623
                     /gene="stcA"
                     /locus_tag="VGY43_000789"
     CDS             39354..39623
                     /gene="stcA"
                     /locus_tag="VGY43_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HEQ4301996.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIERKRTAMTIGHS
                     KQNPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(39971..40369)
                     /locus_tag="VGY43_000790"
     CDS             complement(39971..40369)
                     /locus_tag="VGY43_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEQ4301997.1"
                     /translation="MHRLPNRLIPEEDNNKLSRVAKEVVTEPRLNNPFLLPKKVLSLE
                     DDAAILNHLEEDRNVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTG
                     ITYGDDTLADLAHHLLHSDGVIPSLNDKSA"
     gene            complement(40462..41532)
                     /locus_tag="VGY43_000791"
     CDS             complement(40462..41532)
                     /locus_tag="VGY43_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4301998.1"
                     /translation="MMMLRDVKVKTSSLLVGCAATLLVSLSGTVAADSVHSSDRRFGV
                     GYKEETTSQFSSDQPSQVVLYRGEANTVRFTYTNQMYLMKDIRIALDGSDKSLTAQTV
                     PGMGHVYEGFQTSARGIFTMSGVPESTVPVANPNVQTKYIRYFKVIDDMHNTMYKGTV
                     FLVQPQAWKYTMKSVDQLPVDDLNHIGVAGIERMTTLIKNAGALLTTGGSGALPDNIK
                     VSINPKGGLATITYGAGSTDIIPPAVLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQ
                     SLNEHEAMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNEDEKEKPASDVKVRPAEVG
                     SWLEPATALPSVEMSAEDRLKS"
BASE COUNT        12606 a         8851 c         7267 g        13044 t
ORIGIN      
        1 tcttcccttc tagaaatgta tgaattagga caacatcatc ttttgaaaaa aaatatttac
       61 caccattaat tttatcactc cacaatgaaa atgcttcaat tccctgaaaa atcaaaaccc
      121 ataaaccatc aattattttt gctcctcttt taccaaaata ttcatgaagt ttcgtatgta
      181 aaggattgaa aactacatcc ataaagtatt tatctttata attaacattg tccaaatgat
      241 caaaatttat aggtaaactt tcttcataat ttatcatacc aactggtgta gtatttatta
      301 tgatttctat atcatttaaa atttgttgat cagccaattc cttatatgta atatacttta
      361 aatcagggaa actctttatc aaacttcttg tattctcact aattggctcc ctgtatacaa
      421 ctgttggtga gatttgtagt ttttgtaaag tgaaaatagc agctctagca gtaccgccag
      481 tgcctaaaac acaacatttt gttatatggc taatattaaa gaaaactaat gtattataaa
      541 tacctttcca atcagtatta gttcctgtaa ttatatttcc agatttataa atattgttaa
      601 cagatcctgt tatctctgct actctgtcta aattgtcaat atacctcatt acctctcttt
      661 tataaggtaa agttatattt aatccaatac attttggatc atttatcaga tgtttgattt
      721 tatcttctaa acacactgag tctaccaaaa tttttttatg tttatattca tccagaactc
      781 ctatgttgtg atttagatat tcaaataatt catctgatat agaatgttca actggattac
      841 caagcaatgc agaatacata aatttcatcc tcctacgttt aattagttta ctactaacat
      901 aaagtacaag cattacacag agctaaccat tacctataag tctttagagt atctaaagac
      961 ttaggtatac acctaagtaa cttacccacc aacaataatg ataatatcca ttgctaaaat
     1021 taaaatcggc aaaaattttg aaattttctt cataagtgga cttcctttca gtttttattt
     1081 attgtacaat aaaaaaaaac ggaattgatt tttgttggga aagtgggaaa atatgaaatc
     1141 aaaacttggt gccacactta gaaaagttcg aaaaggaaag caaattagtc tgtgcttcgt
     1201 ggcagatgaa cacctttcaa aatcacaaat ctctcgtttt gagcgcgggg agtcagagat
     1261 atcgtgtatc cgactgatca atattctaga caaattacac attactttgg atgagttcct
     1321 tattttacat gatgaagact ataccaattc cgaaacattt gctaacctgg tacagtatat
     1381 tcgtaagcaa tattcatcac aaaatatcaa taatatagca tgtttacttt ccgacacttc
     1441 tgattacact ctgaattctt ttgagaaaac aatggtaaag tccattttac acacaatgga
     1501 ttcaagcatc attccatcag atgatgaatt acttcaacta acagattatc tctttaaagt
     1561 tgaaaaatgg ggctactatg aaatcctttt attgggtaac tgtgtacgaa caattaacta
     1621 caacccctac ttcctattga caaaggagat gttaaataat tacatttact cttcacggaa
     1681 caaaactaat aaacgaattg tcactcagct tgctataaat tgtttcattc ttagcatcaa
     1741 taaggaggaa ttttctaatt gctcctattt aattgatgag ataaaaacct tgttagataa
     1801 tgaattaaac ttctatgaac agacagtttt tctctatgca acaggttact ttgaatttaa
     1861 gcgccaatta gaaactggag ttgaaaagat gaaacaagcc atacaagttc ttgatatttt
     1921 aaatgaagac aagttaaaat tacattacgc tgaccatttt gataaactag tcaacaaaga
     1981 ttaagtaaaa tcattcttta ccttttaacg aaacgccaat caagggtgtc tcaataaaaa
     2041 atcatctact ctgacaactt ttctctttta cctatcgaca gctaaaaagc cttggaaact
     2101 gctatttcca aggctttctt tgtactctat tgtatcaatt agcttattcc gatttctgtt
     2161 gctattagtt taatcatgaa atctcctaac ttatggccga acatccaaaa aaacagaagg
     2221 aactgccttc tgttttttaa ttggtcatct cttgagcttc ttttaatttt acagatacaa
     2281 ttttagagac ccccgattcc tgcatggtaa ttccataaat actatctgct gcagccattg
     2341 ttcctttacg atgggtcacg acaataaatt gactatcttt gtcaaagcga ttgaggaaat
     2401 ccccaaagcg cttaacattt gcttcatcaa gagccgcttc tacctcatct aaaatcacaa
     2461 acggaatcgt tttaacacgt ataatagcaa acaataaagc cagtgctgac aaagcttttt
     2521 ctccgcctga catcaagtta agagattgga ttttcttacc aggaggctgc acagaaatct
     2581 ctataccagc agacaagagg tctgtttccg ttaaaaccaa atcagcagaa ccccctccaa
     2641 acatctgagt aaaggtttcc ttaaaacttt ttcgaattgc ctcaaaagtc attttgaaac
     2701 gagccttcac ttcgctatcc atactattaa tagtctctag caaaagattt ttagcttttg
     2761 tcagatctgt cttttgactt gttaaaaaag tcaaacgctc atgcacttcc tcatactgag
     2821 taatagcatc actattaatt ggtcctagtg cacgaatagt cttttgtaaa tggtgtaatt
     2881 tttctttggc actttctaag tgatcaatac tatttgttac ctcctttgcg tctgctagtg
     2941 tcatttgaaa atcttctgat aaacttttag cataggctcg taagcgatta gccacttgct
     3001 ctaaatgtgt ctctaacttg gtttgacgac gaataaatgt gtcatttttt tcgctttctt
     3061 tggttatttt ttctgctgtt tcttctaagc gggcctcata gtcctctatt tcaaatctta
     3121 attggactaa acgtttttga gcaccagact tatgctctgt ggcatcttgt aactgttttt
     3181 gccactgggg tagtctttga atgctgtctt gacttacgtt gttgtttagt atgctttcaa
     3241 gtttgagaat attttgctgg cattgcttca gctgagttct tagacgagat tgattagctt
     3301 gctcaaattt cttttcatta agtaaatctc tttcttgcaa acgagcttga gataaagctt
     3361 ggtgaatgtt ttgtgttttt tgcctaacca aatctttgtt ttctttgata tcatcaatat
     3421 cacaagttaa ggcacttttt ttcttagcaa tagctgttaa tgcttcttca atacgagctt
     3481 gctctgccaa taaagattca tcagaatgag tcgtctgact ttgatcaagg gcagctaata
     3541 aagcctttga atcttcttgt ttttcttgca attgctgata agccatttga gctctttgtt
     3601 cagctaagcg tgcctggtca ccggctaatt tcaattgtgt cagttcttct ttttttgcta
     3661 tcaaatcgct ttgcaaggca gctacttctt tttcagttat ttttaattgc tcaactaatc
     3721 gcgttaattc ctcactgatt tgttctaact ctggtttgat aaaagttgta ttgctttgtc
     3781 tattagctcc tcctgaaaaa gaaccacctg gtcgtaattc tgttccatca agagtaacaa
     3841 ttcttacctt atatcctaat aagcgcgctg caatattagc ttggtcaata gtttcaaaga
     3901 tagcagtact agataaaagg ttttggataa tagctgaaag actatcatca tagcgaacca
     3961 atgattctgc agttcccaga taaccttcac aagtcgctaa ttgacgatga tagtgttctg
     4021 acaatgatct agcctttata gtagttaaag gtaaaaaagt tgctcgtcct tggcgatttt
     4081 ttttcaaata agcaattgct ctttttgctg cagcttcgtc tgttacaata atatgctgac
     4141 tattagcacc taatgcaatt tcaagagctg tttggtaatc agaatcaaaa gaaaggtgtt
     4201 cactgactgc acctatgatc cctccaagct ttttttgtga ttgaaggaca gctcgtactc
     4261 ccgcatagaa ttgactatga cttttttgaa tagattctaa gctagcctta cgagcttctt
     4321 ttcctttttt ttgatccaac aagtcaaata gtctttcttg attcagttgg taatctcttt
     4381 ctaattcctg aacgcgttta tcaccttctt gataattttg gagcaacatt tcgacttgct
     4441 ctttttgagc tttataatga gcttgagctt tttgagactc gtcattaagt tgatcaagct
     4501 tagtaacaag tagctgatat tcttgagcct tatgttgacg agcctgtttt tctttgtcta
     4561 aatgggcttt taaagctgtc agctgatttg ataaggccgc ctctttttgc atcaataata
     4621 caaactcttc tcttagagtt tccattaatt ggtcgggatc acttgaaaaa cgctctaatg
     4681 cattgctcaa ttcgtttaac tgttgtttga catcacaaag ttgttgatca atatgcaata
     4741 attgttctgt acgctgcttt tcttctgctt gaaaaccatc caattgttct tgtaactgtt
     4801 cgagatgttt tttggcttct gcctttttct ctgcttcttg gccactttct agcttaacca
     4861 attcaatttg cttttccaag tcagctatta gcttggttaa ttctaataat gttgtttggg
     4921 tttgatctga ctcttgacta agaacctgct ttttttgctt gaatttttgg taatcttctt
     4981 ccatagattg acgcttagcg taataagatg ctaagtcttg ttgtaaagca gctaaagctt
     5041 cagtatcttt agtctgtctt tcttgagcta tatcaatatc tttgactaga atatctagtt
     5101 gtagttgctt acgattggca tcaagttcta aaaattgttt agctacttta gcttgctttt
     5161 caagtggggc caactgcgtg tctagctcat aaataatatc ctctagacgg tctaaattat
     5221 cttgagtttg atttaattta atctgagttt cttttttacg tgttttatat tttaaaacac
     5281 cagctgcttc ttcaaaaatg gcgcgccttt cttcaggttt actattgaaa atttcctcta
     5341 cacgaccttg agaaataatg gagaaagaat cacgaccaag ccctgtatcc ataaacaaat
     5401 catgaatatc acggagcctt accttgcgac catcaatcag atagtcacta tctccatttc
     5461 ggtaaatatg cctttcgaca cggatttctt tcttggcagt ttttataaaa tgatcggaat
     5521 tatcaagaac aaccgctacc ttagcatagt ttagaggatt acggttttgt gtcccagcaa
     5581 aaatgacatc tggcatcttg cccccacgca gatttttagc acttgattct cctaaagccc
     5641 aacgtaaact ttctgtaata ttacttttac ctgaaccatt tggtcctacg actgcagtta
     5701 ctcccttatc aaattcaatt ttagtcttgt ccgcaaagga cttgaaccct tccaactcaa
     5761 tttcttttaa aaacatctaa acctcactaa gttgggcaag ggcattttta gcagcatctt
     5821 gctccgctaa ttttttagac ttacctaaac ctttactaag gacagcacca ttaacaacta
     5881 tcgatacctc aaattgttta gcgtgggcag gtcctttctc actaatgact tgataatcaa
     5941 tagccacatc accttttgtt tgcaaaaact cttgaagaca agttttatag tctttaaccc
     6001 tttcaaaatt ccctttttcc acctgaggaa tcatgacttg tttcaagaag cgacgtactg
     6061 catcaatccc cttatctaat aaaagagcac ctaaaaaggc ttcaaataag tctcctaaaa
     6121 tagtatcacg acggcgacca cctgactttt cctcaccttt tcctagtttg atataagcgt
     6181 caaaagaaca aaatcgtgaa aaacctgcca agctttcctc acgtacaatc atggaacgta
     6241 acttagacat atctccttct gtctttttag gatactttgc aaataaatac tctgaaataa
     6301 tcaattgtag aacagcgtct cctaaaaatt ccaagcgttc attatgtgaa acgtttagga
     6361 gacgatgctc gttagcgtaa gaggtatggg taaaagctgt ttctagtaaa gtcaaatcat
     6421 taaattgaat atcaaaagat gttgagagta actcttcaag ctgtttcata aaaaatccct
     6481 ttcatatttg tcagtagacc ttatttagta taccaaaaat ccacctagaa aaccgactct
     6541 aagtggattt ttcgtgattt attaaacatc ttaaataccc gtcaaaggaa actttctcat
     6601 acaatcaaaa gactctacac tatctgaggg gaatttccca ctacagtccc actacagtcc
     6661 cactacagat agtatagagc tattttgttt ttagtctgaa caactaaaaa actaccttat
     6721 ctttataatc ctcaacacct ttgataaata gatcagacaa gccaaaacta caggctaatt
     6781 taagtctatt gatgctctaa aggataacca atgagagttc attgaactca gaagacaata
     6841 cgctttaaga catcaaaaaa tagccctgac tggtatatca ccaatcagcg ctactttgca
     6901 tattctcttt tagtttctta tctcaaatat cagttaatgg acaagcagta tctggagagg
     6961 tatcatggac cgtaaagtct gtacctactg ctaaatctgc catagccagt tgattgacca
     7021 tcgtcatatg cgctaactct ttgatgttat tttctttact cagatgacct aggtatattt
     7081 ttttggtatt gtaccccagg cttctaatca tggctcccgc tccatcttca tttgataaat
     7141 gtcctaaatc agataaaata cgctgcttca agctccaagg ataagagcct gatctcaaaa
     7201 tttcaatatc atgattggat tcaatcaagt agccatctgc attttcaata atacctgtca
     7261 tcctatcact gacatatcct gtatctgtca acatcacaaa agacttatta tctttcataa
     7321 tccgataaaa ttgaggatca atagcgtcat ggctgactcc aaaactttcg atatcaacat
     7381 ctccaaaggt caaaacttta tccctttgga aaatatgttt ttgtgaggca tcaagcttac
     7441 ctagcatatt gcactcatcc atcagctgcc atgttttttc attagcatag atatccaaat
     7501 ggtatttgcg ggccataacg cctacaccct taatatggtc agagtgctca tgggtaatca
     7561 aaatagcatc caaatcctca ggtttgcggt caatttcagc aagaagactg gtaattttct
     7621 taccagtaag ccctgcatca atcaataagc gttttttagg tgtttctaaa taaaaacaat
     7681 ttcctgtgga cccagatgct aaaatactat atttaaaacc actctcattc attgattagt
     7741 ctacatcttc ctcccattct tcatagatgg ctgcatcttt ttcataaggc aagacaatag
     7801 taaaggtcga tcctttacca tagtcactct tagcccagat aaagccatgg tgctgcttga
     7861 tgatttcttt agcaatggca aggcctagac cggtccctcc ttgggcacga cttcttgcct
     7921 tgtctacacg atagaaccga tcaaaaataa gaggcaaatc tgttttaggg atacctagtc
     7981 cttggtctga aatggaaata attaattggg tatctgttgt tttcatacgg actgtaattt
     8041 ttccaccatc tggagaatac ttaatggcat tgttcaaaat attctcgata acctgtgtca
     8101 ttttatcatt atcaatttca agccagacag aggtaatagg gtaatctctt acaatttcat
     8161 agacttttcc tgtacctgta tgctgatttt taaccaaatc aaatctgttt aaaatagaag
     8221 ttataaaagc agtaaaatta gtcatctcta ctgctaattg ggttacttga ttatcaatcc
     8281 gagacaggtt taaaagatct gaaatcatac gcatcatccg attagtttca tcaagagaaa
     8341 cttttatgaa acttggagca atatcttctt taagtgcacc ttcatcaaga gcctccaagt
     8401 aggatttaac cgaagttaaa ggggtcctta attcatgact tacattagaa acaaaaagac
     8461 ggcgttcacg ttcttctttt tcttgttctg tggtgtcatg gagcaccaca accaagcccg
     8521 aaataaaacc actctctctc ctattcaacg caaaacgcaa gcgtaatgaa acaaactcac
     8581 ccatatcatt tcggctatta acagttacca ctggtgtttt ggataccaaa tcacggtagg
     8641 tatatgaagt atcaccttct aacaaatctg taatgttttt ctttagtgcc tcttctttac
     8701 ttaaatttaa ttgcttgcga gctgtctcgt taatcatgat gattttacca gaccggtctg
     8761 tagcaagtac accatctgac atataagcca aaatacttgc caagcgattt ttttcttggg
     8821 caagattttc atgcgtcaag cgaaaaacat ctgacaggtc atttaactgg tctgaaagct
     8881 ccattaactc aatgtctgct ttttcgtcga ttatatcagt atagcgacca ttaatcaagt
     8941 ctcggatttt atggctcatc atccgaataa tacgtgcatt tcggtaatca cgcaccgcaa
     9001 gatggataaa gtaaaaagca acaaaaacaa gtaagataag gatcgctaat tcaaatgtgg
     9061 ataagtttcc aatgatatct ctagtcataa gatttcatgt agtacccaac accacgtctt
     9121 gttaaaatat actcaggacg acttggtgtg tcttcaattt tttcacggag acgacgaaca
     9181 gtcacatcaa ccgtgcgcac atcgccaaaa taatcatatc cccaaacaat ttccaataag
     9241 tgttctcgtg tcatcacctg acccatatgg ttagctagat gatgcaatag ttcaaattca
     9301 cgatgagtca actctacctc ttgaccatgt tttttagcaa caaacgcatc tggtaaaatc
     9361 tgtaaattac caatggttag ttcctgtgta cctgaagaag cattttcttc tgcaacagcc
     9421 gtttcaatag tttcggtacg acgcagatga gccttgacac gcgccagcaa ttcccgatta
     9481 gaaaagggct tggtcacgta atcatcagcc ccaatttcaa gtccaataac cttgtcaaac
     9541 tcactatctt tagccgacaa cataataatc gggacatgac tggttttacg aatttccttg
     9601 gctacttcaa gaccgtccaa ctcagggagc atcaaatcaa gaataattaa atctggcttt
     9661 tcttcttcaa aaatggttac cgcttcgcgt ccatcaaaag ctgtaacaat gtcataacct
     9721 tcttttgtca aattaaactt aataatgtca gaaatcggtt tttcatcatc cacaataagt
     9781 atttttttca tgtctatacc tcagaaagtt cttgtaattg atattacaat ttgtgatttt
     9841 tgtggttaat aaaaaatcac aaaactatat ttttctaaat tatttctacc tgattatacc
     9901 aaaaattcag cctaattgac aatgacgact accgttacaa atagagtact ttctaaaacc
     9961 aaccctttat aggatgaatt tggcgtttga attgcttagc agattttttg actctggcaa
    10021 aactactctt gttgtggtaa gcaaaaagtc ctttggcatt aaaataagag aacataaagt
    10081 catctttttg agctctaaac cactgacgaa atactctttt tggcgttcga aatcctttaa
    10141 gggtgtctct tctaaactga ggatcgtgac ggctaatcgg atcaacatct aaatcccaat
    10201 gtctaggacc atctgtgcca tagttaaaag atgcaccatt gacaattcct ttttcggtca
    10261 ctacttctgc atcaacttca ttaagaaaaa agcctgtgct atctagaata aattcggtat
    10321 gaaaccaaag aagtactttt atattatagg aaacttcttg acttggaaaa atgactttat
    10381 tatcttcaaa tcttagttta ttatgtaacc tggcagaatc catcaaggta taatctggtg
    10441 cttgccgcca caaacaaggc ccttttttag acctcaaaaa aagggccaga gcttgggcgt
    10501 ctgtcatctc aatcatttta taatggtttc tgatagattg agcttgttga ctagagatga
    10561 tataacgaaa ttgatgcaaa cgcttttcaa gctcacctgc ttggcttagt gttttgccag
    10621 gaaaagcttg atcaactaag ctagccaact ctttccaaaa catatgatct ggcaatagag
    10681 atggatggaa tcgggtgagt agcgtttgag tttcatgcaa ctgaccactt agctcaaatg
    10741 gcatctctac caaatcaaga agaaacgtta gtaactgctt agctgattgg ttttcttttt
    10801 caataggcca tattacccag aaagttggag aaccaagtcg attatcaatg ataggctctt
    10861 tagctatagc acgaaatgct tggtttgata aacctgcgtt ttgatagcat ttcaaggcct
    10921 gatagcgatc taagatagct tgtttcatgg ccttctcctc atcttttttg accatattat
    10981 aacacatcta aagctgaatc gtcacttgta tctcactata agcaaaacga aacctgaagt
    11041 ggttaactaa gccactgttt gggtatttta tttaaaagaa cttctcgatt aattttacca
    11101 ttatctttta aaggcaaaca atcaatcaca agatagtact tgggaagttg tccagagttt
    11161 aaataaagag ctaaaaagtc tttaataggt gctaggcaat ccttcttagt caaaactaat
    11221 actaatatta gggtttcgtt ttctcctttt cctatcttta aagcgtgcgc ttctttgacg
    11281 tttggcgctt ggtgagcgag ttcaactagg ctaggcaggt ggcatttcac tcctcgttga
    11341 ttaacccagt catcttgtcg cccttctaaa attaaacccg ctgggctcat ttttcctaag
    11401 tctgagacac tgtatggttg tgacattcct tctacactat aaggagtctc tacaaaaatt
    11461 tccttatctt tgaaactgat agacacatca ggaaagggct gtcctaccaa accattaatt
    11521 ttgacagcag ctctgccatt acaccacgtt ataaaagata attcactagc cccgtagaaa
    11581 atgacaattt caagctgagg aaattttttg taataatgtc ttagtaattc ttgtgatatc
    11641 atttgcgaag aggtcaataa gtgagtcgca gtcatgttgt tcttagtcaa ataaggtagc
    11701 aagcgattta ggtaggtcgg taaaaggtaa aggtgactca ccttttttgc ttgccataag
    11761 cttaaccacg ttttcaaaga cagcttttgg cttaaaacca gacatccccc ggcccatagt
    11821 tgagctaatg ctaagttaag attgccagta aaactaaaac taccatgtaa gaatagacaa
    11881 ctattaccag tcataccaaa caccttattt tgataatcaa aaagtctcgt ccaagttgat
    11941 agacaacgcc aaaataattt tgctttgcca gttgttcccg aactcaaaac agcaaaatca
    12001 gcttttttaa gaagctcacc atcgacgtgt tttatttgct gctgaaatgt acctgagata
    12061 ttagggtgta aaatgatagg acaactgcct tcttttaatc ctcgtaaaaa agagagtaac
    12121 tgattaagat agcgactatg actgatgata tatggtacac tgtcttttat tgtctgatcc
    12181 tttattaaaa ccgcttgcca tagctcttga taagtcaagc ttatctgatc ggctacgata
    12241 gcttttttat ttgggcattg ctttgcccaa tattctagct ttgtcagcat gactaaactc
    12301 cttatgatat tttagtaaaa cagcaaaccc ttggccacca gctgctgcta tagcagctat
    12361 tccatagtgt ccatttttaa tctctaaagc cctcattaag tgcaatatta taatggctgc
    12421 tgaggcacca tagggatgac cataagctaa tgcaccacca aatatattat agcggtccaa
    12481 taaatctggg taatgggttt caaataaacc atcaataacg gcaaaggctt cgttccattc
    12541 aatcgctgtc atatctgcca tccctagacc atgtttttcc aaaaggactt gactagcctt
    12601 aatcaccatt aaagggctac gctgtgggtc tcctgctact tctaccacat caatcagttt
    12661 aaaagctgaa ggctgactac ttagctgtaa aaaggcagca gcatcatggg ttaggcaggc
    12721 attggctgca ctaatcacgt gatcttctcc taagataggg ggtacctttg acaacacctt
    12781 acttgacaag cgcggtcgaa taccttgatc actggctcct ggcaggtcta gaataagatc
    12841 agctaacagg gcttgctcct ggcaataact agccttttga tgacttctca atgtccagtg
    12901 attcaaatac tcctttgtaa agccatgctc tcttgccact cgttctgccc cttcaatcat
    12961 cgcaaaaggg ctgatactat ctggagaaaa ctgagctacc ttgtaggctc cttggcgcca
    13021 atcagctgaa gcatataccg attcaggttg taaggagctg ctttcaatcc ctcccactaa
    13081 aaggttgctt gccatacctg ccttgatttt agcataaccc acggaaagag ctgcaccagc
    13141 tgatgcacac tgcatatcaa ccgtcaaagc agagacagat tctcctaaat gagaatacag
    13201 ggtcatcaag cgcccaatat taccacccgt tccgacggca ttgccacaaa tcacttggtc
    13261 aatgggaact ggatacttat tttgtaaagc gttgatgagc tttgctccaa ggatttctgg
    13321 ttgttcttta gcaaattgtt tccctactaa accgataggg gttctaaggc ctgcagcaat
    13381 ataaacatcc gtcattatat tgacctcctt tattttcgat gtgcttaaat ggttattata
    13441 taattatttc tgatggtttt cttttttgaa ctaataactg ctaaaaatac acctaaatta
    13501 atttagagaa tctctttagt ctcgctagtg tgccatcaat aaaatctata aaattctcta
    13561 acgtcattga aatgtcaagt cccacaacta ttgtcgtaga agtcacttac tttgttgctt
    13621 taacattcaa actgtaacct ttgtttttga tacagggtga ctttattata ctggaaaacc
    13681 attcctaaga aaagaaaatc ttatatagaa taaagaatta gacaccataa aaaagctaag
    13741 ctgtgacact taactttttt atggtattga caaaccttgt ctttactatt tattgatagt
    13801 taatgcctct aactaaaata aaagccatgt ctgtatcagc ctgcaaggca tctgctaagc
    13861 tggtatcgtt actagatttg acaggtctca taaaggcaaa agatctcaaa gttccataaa
    13921 tgttatctag caattgcatg caaccacttg aaatatatct gcttatgtta ttttaccgcc
    13981 cttaatttag accaatctgc tgatgatggt tccaaccaat gcctacgctt ggtaaaccat
    14041 cacaaaaaaa agcagccgtt tttacaacag ctgccttcct tcattatcta ggttttcata
    14101 ttctgaccta aacgattttc aatttgttta agagtctctc taggaacctg cactttcata
    14161 agcatctagg ccccatttcc aaagcttaag cgacaaggcc aaaaccagta acgacaccac
    14221 taccaagcct ccaatattaa agagcaggtg ttgacctgtt aaaaaataag aagcagggta
    14281 ataagctgta aaagcaaagg gaatgataaa actgattaac caccgcaaaa aggaatggta
    14341 aatggacata gggtacttgg aaaagtcatt gaacatgtaa aaaatataga taactgcccc
    14401 agactgcttg gtccaaaaag aaatgctggc ggtcgcaatt tttaaagagg tgtaaatcaa
    14461 ggtcgcaaaa ggaataacca aaataaacaa aagcacctta ggaagagtcc atacgatact
    14521 accagccgtg gtcactaata agataacccc aaccaataat tcacccaggg catccacttg
    14581 aaaggtctca accaaaacat gaaacaaagg actaattggt ctggtgaggt acttgtcaaa
    14641 ttctcctttg cggacaagcc gttgccctaa agcccaaaga ttgtcaaaaa agaggtgatc
    14701 aattcccttt ggaatcaaag aaaagccata aataaaggca atttgttcaa acgtccagcc
    14761 ttctaaagaa gggatatgtt ggaaaagtac cgataaaaag agcagattaa gtccctgagt
    14821 gagaaaaaca cctagcactc ccaccacaaa atcaaccttg tattccataa tttgtttgag
    14881 gtattgtttg ataaaaatag cgtgcatacg tctcaatttt gccatctcac cctccttgaa
    14941 tcgttaaatg gtactgaacc tttttccaga tgacttgcga taagactacc atcaccagta
    15001 accaaaagat ttgcaaactt agggcaacca ttatctgact aaggctgtat ttcccaatga
    15061 caatcataac tggcgtgtaa accaaagagg ataacggtag aaaactaagc actatagaaa
    15121 ccattttagg aaaaaaagcc aatggaatca aactgcctga cataaaggca accaaggcat
    15181 ttttcaataa attagacccc caaaggtttt taaaaacaaa tgctgaaaag ccaaaacaaa
    15241 tgttgaaata aaaattgatt aaaaaagcta ataaaaggct aactaaatac agacaactgc
    15301 tggctaggac ttgcaagata gacagccccg ccatgacttt aataccagat aagaccacta
    15361 aaaaaggaaa gccgacactc attagcacaa tccagcgaaa accaatttcc ataaagaggt
    15421 aagaggctgc aaaatgaact ggtcgaagca ggcgcatgat gatagaacca tctttcactt
    15481 cttcgccaat cataaaggag ctgtctgatt tggtcagtaa agtggtcaca aaactcatga
    15541 taatgtaaaa ggtcatgtca gacagagtaa aaccattgat taaggattgc ttagacgaat
    15601 caaaaacagc cttccagagg taataagcca caaaagcccc catgacatct ccaatacgat
    15661 acaaaaagaa attaacgcga taggttatta attcctgaat tcctgcactg agaaaggggc
    15721 tataacgttt ccaaaatgac cacatcttaa agctcctttc ggtagaaacg acgaacaata
    15781 tcctcaatat ctacatcagt catcttcaaa tccctgaccg caaaatcagc tatggttttt
    15841 tgaataatgt ccgctgtttg atagcgcgaa ctgtcatatt gaatttccaa agttaattcg
    15901 tgtcgttcca cagttatatc aggcaaacca agaaactgag aaacaacttc ttcctgtccc
    15961 gcttccaatt caaaagataa gcttttcatc ttcccaaatg tttgtttgag ttgggtcacc
    16021 gtgccatcaa agatttcttg gcccttatca atcatgataa tccgatcaca gagctgttca
    16081 atatcactca aatcatgggt cgtcagtaaa atagttgtct cttcttcttg attaatttga
    16141 gtaatggcac gccgaatgtt gtccttcaca gaaacatcaa gtccaatcgt tggttcatct
    16201 aaaaacaata ctttaggatt atgcaacaag gaagcagcaa tatcagctcg catccgctga
    16261 ccgagtgata aggtccggac aggatcctta ataaactcat tcaggtccaa aacctcattt
    16321 aaaaaatcca tgcgcttgcg aaaggctttt tcaggcacat cgtaaatttc ttttaaaacg
    16381 acataggtct cttgcaaggc caaatcccac catagttgtg ttcgttgacc aaaaacagct
    16441 ccaatgtctc tcacataatc ttgacgatta tcttgtggaa tctttccgtt aatgcgacag
    16501 taacctgatg taggctttaa aatacctgtt aacatcttaa tcgttgttga ttttcctgca
    16561 ccattggcgc caataaaacc taaaatttgc cctttgggta cctcaaaaga taagtcctta
    16621 accgcctcaa agatttctct ttggggatga acaaaggact tcaaggctcc ctttaatcct
    16681 ggctctttaa tggttttgga aaaatttttt tgaaggtggg acacttctat catgaccatt
    16741 taccattcct cgtttctgtt atcgtcttat caccgttact aaacaattta ttataacacc
    16801 ataaaaaaga cggtgcaatc gtttgcttaa ttttttaaga aagaaaaaga agcccataag
    16861 gacctctttt tgccattgat taagcttgtg catctggacg tgacttgcga gcaatgtctg
    16921 ccaagatgtt ttccacaaat tcttccacag attcagtgtg agtcgcctta ctaccatagc
    16981 ggcgaacatt gactgatttg tcttccattt ctttgtcccc aacaattaat tggtaaggaa
    17041 ttttgctggt ttgagacgca cgaatcttgt actgcatttt ttcattgcgg tcatcgacat
    17101 ctgcacgaac accacggtca cgaagggttt ttgctacttc ccaagcatag tcaatgtggg
    17161 cttcatttga aattggaatc acggttactt ggtgaggtgc caaccaagtt gggaaagcac
    17221 ccttgtaagt ttcaataagg atagcagtga aacgttccat agttgagata acaccacggt
    17281 gaatcatgac tgggcggtgt tcttcgccat ctgcaccaat gtatttaagg tcaaagcgtt
    17341 ctggcaacaa aaagtccaac tgaatggttg atagggtttc ttcgttacca agagctgttt
    17401 tcacctgaat atcaagctta ggcccataaa aggctgcttc accttctgct tcaaagtaat
    17461 ctacacccat ctcatcaagt gcagctttaa gcatactttg agcattttcc cacatctcat
    17521 cattgtcata atatttatga gtatcgttag ggtctcggta tgacaaacga aaacgataat
    17581 cagtcaagtt gaagtcagca taaacatcaa tgattaattg aagggcacgt tgaaattctt
    17641 cctggatttg ctctggtgtt acgaaaatgt ggccatcatt caaggtcatt tcacgtaccc
    17701 gttgaagtcc tgatagggca cctgattttt cgtaacggtg catcatgcca agctcggcaa
    17761 tacgaatagg caattcacga taagaacgca catgattttt atacacttga atgtggtgtg
    17821 ggcagttcat tggacgaaga acaaactcct caccatctcc catatccatt acagggaaca
    17881 tatcttcttg ataatgatcc caatgacctg atgtcttgta caattctaca gaagcaagtg
    17941 gtggtgtgta aacgtgttgg tagcctgatg ctaattcttt atctgtgatg tagcgctcaa
    18001 gtgtacgacg aatagtcgct ccatctggta accaaaatgg caagccttga ccaacttctt
    18061 gactaatcat gaacaagtca agctctttac caagcttacg gtgatcacgt tctttggctt
    18121 cttctagacg agtcaagtaa gctttgaggt cttttttatc aaaccaagct gttccataga
    18181 tacgttgcat catgttattg tcgctgttac cacgccagta agcacccgcc acattgagca
    18241 agtggaagac ttggatacgg cctgttgatg gcacatgagg gccacggcaa agatccacaa
    18301 attcaccttg acggtaaacc gtcaagccag caccagcatg ctcattaatc aattctacct
    18361 tgtatggatc atctttgaac aattccaaag cttcttcttt ggtcacttct tcacggatac
    18421 atgggtaatt ttctgtcacg attttttgca tttcagcttc gatacgtggc aaatcttcgt
    18481 ttgaaatttg gccttcagca ttatctgtat catagtaaaa gccttctgca atggcagggc
    18541 ccacacccaa atgaagattt gggaacaagc gttttgcagc ttgggcaaat aaatgggctg
    18601 cagagtggcg aagcacctca taagcatctt tgtgatcagg tgtcacgatt tcaatactgc
    18661 catcttcttc aatggcacga gtggtgtcaa tgagttgatc attgaactta ccagctaaag
    18721 cttttttagc caatgatttg ctgatggact cagcaatgtc aaacgttgtt acgccagatt
    18781 caaattcacg cacggcgcca tctggaaaag taatcttaat catttgcttt ctcctttaag
    18841 tcagttaaga tttccactaa aacatggata gtaagacaaa ttagggacaa gaggttagtg
    18901 aatagctcaa taccaccacg tagaagaaca ataccttatt cacgaatcta ccctccctag
    18961 tccttaaaaa caaggctaat cccctccaaa acaaaaaaac tgaccgcatc ccaaaggacg
    19021 caatcagcgt ggttccacct taatttatgc aggacaaaaa acatgccttg cacctctagt
    19081 ggcgataagg gggccaccct tttatgtttg cataaaaacc aggaaggagt atcagattag
    19141 ctatccttgt gctctttcca ccaaccagca ctcgcttaaa agattctgtc caatctaact
    19201 tgtcttcaag attattatag caagttttca aaaatttaca agccttaatc cagaaaatct
    19261 ttgatagcat ggaccagctt gataggagcc ttgactactt ttactgaggt gatagctgtg
    19321 accttagcag cacgtttagg caagtgaata gcaccttgca ctaattttag agaactactt
    19381 ttaccagaat gattaagata aagtctcagc ttttgagctt ctttgctatt tctagcaatt
    19441 aacgtatcta aatagaacgt gtaaatagat tttccaaagt gctgtgctga gatttcataa
    19501 cgtttttttg ctaataaccg cttatccata actggtgttt ttagtatggc atcaataata
    19561 gcatcagtta aatctgtttc agcgtaataa agagtgccaa acattttatc agtcaccaca
    19621 tcatctaaat aaggattgcc atgagcaata ataggagtgc cactagccaa actttcaata
    19681 taggtcaagc cctgagtctc actagttgat gctgagataa agaaatcaca agccttatag
    19741 tacagagcaa ccttatcatg aggcaccatg cctgtaaagg tcacgtgttt gtcaacctct
    19801 aactgcatcg caaagtgttt caaatcttgc aaataggggc catctcctac aataataagc
    19861 tttatcttgg cattttcagc caaaatagct ggcatctgat tgatgatagc ttgaatattt
    19921 ttttcataag aaatccgtga caaactcaat aacatggttt catcaccagc aatgcccaat
    19981 tctgctttta agttggttac ttcttctgct gtgatgtcat cacgaatata tttttccaaa
    20041 ggaatgcctg ttgggataac ccgcttaggg atagtcactt cgtaaccttc tagaagattg
    20101 aggacaatcc tacttgggca gataacccca tccaaatcct tcaaatagcc cctaagaaga
    20161 ggtttgacca tacttggtcg aatgattttt ccgttggcaa tataactcac gtagtcctca
    20221 tattgggtat ggtaagtatg gacaacagga attcgcaaag ctttgcctat cattttccct
    20281 aataagccta agctaaactc agtttgcgta tgaataatat caagattata gtgttttgca
    20341 attttgtatg acgaaatgag gccacgataa accacacgtc tatccgtaaa tgacacaaaa
    20401 ggaacacttg gcagtcgaat aatggtcggg tcttcaaagc gtttgacatc tctatcagta
    20461 gtggtgaaaa tataaacttc gtgaccttct ttttctagct cttcttttaa cgtacgaata
    20521 ctagtagcga ctcctgaaac ttgtggaaaa taggtatctg tgaatagacc tatacgcatc
    20581 ttataactcc attacttttt tatagacatc tactaaggca tggccaaccg tttctaggcg
    20641 acgactctgg gcaaccttgt aaccagcttc aactttgttg ctggcaccag aaaagacttt
    20701 tttcagagct tctataaaac ctggtatatc ggttgctaat tccgcactac tttgatcaac
    20761 ccatccgtag taaactggta tatcacgtaa aacaaggtgc tggcgactgg ccaaggcttc
    20821 taagacaaca atgccttctg tttcttcacg acttggaaag aaaaaggcat ctgcaccagt
    20881 catggcacct tcataaacat cccctttaat gtatcctggg aaaataagat ttttcgggtg
    20941 gttaccattg accatttggc gaacttgagc aggaatgacc catttgttgg tctcgccaaa
    21001 ccagataaaa cgaacatctg gcatagcttg ggcaactttg acaaagtcat caattccttt
    21061 cctcagaaaa aataatcctg ctcccataac cactttttca ccctctttaa tgtcaaagta
    21121 gcgacgaaaa gctgcttcct ttttaggatc tgctccgtac tgctccaaat caatcccatt
    21181 tgacactgca aaaataggtg acttcactcc ataactctca atcaaagact tagaatatag
    21241 ggtaggggta atgatagcat ctgccttatt gtaaaagtga caaaggtatt ttttaaacca
    21301 aggagataat agatttgaaa aaataaaaga atttctaaaa tcttcttctg tagaatgccc
    21361 atgcatgata accttcttac cagctttttg tgcttttatc atcagcagcc aactttttaa
    21421 accataggta ttgagatgaa ccaaatcata agtttctctt ggattagtcg taaaatgttg
    21481 accaacaagt gacaaggctt tagcctgatg cttaatcgct cgaccaattc ctgattttct
    21541 tagataattt tctgcttcta aatacaataa gactttcata agttctatta tagctcattt
    21601 tatagtattt ttcactaaga catgcaaaaa tcagccctaa ggctgatttt agtattgaag
    21661 aaacagtcta ttgtgatact tttgttagat ggtgctcata agtcacagtt acttagttgt
    21721 cccacgtttt ttaataccat gattcaaaag aatttctttt tcttccaact cttctttgtt
    21781 catgatttta gtcaacatcc gcatgctaac agcacctaag tcataaacag gttgactgat
    21841 agaactcaaa ttgggacgag tgtattgaac cactggtgaa tcgttgctag tgatgatttc
    21901 aaagtcctct ggtacgcgtt tacctgcttc aaacaagccg tttaaaaggc ctgctgccaa
    21961 ttcatcttca gccacataag ccgctgttgc tcctgagtta atgacgcgct gcgccaattc
    22021 aaatccttct ttataagaat agttcgcttc aaaaacaaga ccttctttga agtcaagctt
    22081 attgtgcttc aacccttctt tgtaccctgc taagcgcact ttaccattga tatcatcaat
    22141 gagtggtcct gacacaaaag cgatacactt atgattttca gctaaaatat caacaacgtt
    22201 tgacaccgcg gctctatagt caatgttgac gcttggtaat tgatgatcaa gatctacagt
    22261 tcctgccaaa acaactggag tacgagagcg tgaaaactcg gcccggattt tttctgtcaa
    22321 gtgatgcccc ataaaaataa taccatccac ttgcttggca aaaagggtat tgacaacatt
    22381 aacctcctta tcatcatctt catcactgga ggcaagcaca atattatatt tgtacatagc
    22441 ggcgatatcg tcaataccct tagctaagat agaaaaataa ctatttgcaa tatttggaat
    22501 cacaacgcca acggttgttg tctttttgct ggcgagacca cgcgcgacag cattgggacg
    22561 atagtcaagg cgatcaataa cttctaaaac tttcttacgt gtattttcct taacattttt
    22621 attgccatta acaacacgac taacggttgc cattgaaaca ccagcttcac gggcaacatc
    22681 ataaattgta atggtatcat ctgtattcat tttttatctt cctttctatt tgaaaatgac
    22741 gctttcaaaa agtattttag catgatttgt aaccactttc aagtgttata ggttaatttt
    22801 tgaaaaagtt ttcaaaaatt aactcgaagc ttgatttttt aagctttttt tgaaaaaata
    22861 gtaagtagaa agaaggttag cctatgacaa aattagacca aatacgtttg tatcttgacc
    22921 aaaagggagc tgaattggcg attttctcag atcctgttac gattaactat ttaactggat
    22981 tcttctgtga cccacatgaa agacaactgt tcttgtttgt ctaccatgat ttagctcccg
    23041 tgctttttgt acctgccctt gaggtggcca gagctagcca ggccatatca tttcctgtgt
    23101 ttggttatgt tgattctgaa aatccttggg aaaagatcaa ggccgtttta ccaaatacag
    23161 cagccaaaac catttatgct gaatttgacc accttaacgt caataagttc catggcttgc
    23221 agactatctt ttcagggcaa tttaacaatc taacccctta tgtccaaggc atgcgcctca
    23281 tcaaatcagc tgatgaaatc aataaaatga tgattgccgg gcagttcgct gataaggctg
    23341 ttcaagttgg ttttgacaat atttccttag atgctaccga aacagacgtc atcgctcaaa
    23401 ttgagtttga aatgaaaaaa caaggcattc ataaaatgag ctttgacact atggtcttaa
    23461 ctggaaataa tgcagccaat ccccatggca ttcctggaac aaataacatt gaaaacaatg
    23521 ccctacttct ttttgactta ggtgttgaga ccttaggcta caccagtgat atgaccagaa
    23581 ctgtggctgt tggtcagcca gaccaattta aaatcgatat ctacaatctc tgcctagagg
    23641 cacaactagt ggctattgac tttatcaaac caggtgtaac agctgctcaa gtagatgctg
    23701 ttgctcgtca agtgattgaa aagtctggat atggtgagta cttcaaccac cgcttgggac
    23761 atggtatcgg catggatgtc cacgaatttc cctccattat ggctagcaat gacttggtcc
    23821 ttgaagaagg tatgtgcttc tctgttgaac caggcattta cattccagga aaggtcggtg
    23881 tgcgcatcga agactgtggc catgtcacta aaaatggctt tgaagtcttt acccatactc
    23941 caaaagagtt gctttatttt gaaggctaag cccctaccat ctggttaaac aaaccctcgc
    24001 gaaaggaagg tattcgtatg gatcaaacca ttcatcatca aatacagcaa gcactacact
    24061 ttagaacagc cgttcgtgtt tataaggaag aaaagatttc tgatgaggat ttagccctta
    24121 tccttgatgc tgcttggtta agcccttctt ctgttggctt agaaggctgg cgctttgtcg
    24181 ttttagacaa caagcctatt aaagaagaaa tcaagccctt tgcctggggg gcccagtatc
    24241 aactagagac agctagtcac tttattcttt taatagctga aaaacatgca agatacgata
    24301 gccctgctat caaaaatagc cttttacgac gtggtatcaa agaaggtgat ggtctcaaca
    24361 gccgcctaaa actctatgaa tctttccaaa aagaggacat ggatatggca gataatcctc
    24421 gggcactctt tgattggaca gctaaacaaa cctatatcgc tcttggtaat atgatgatga
    24481 cagctgctct tttgggcatt gatacttgcc ctattgaagg ctttcattat gataaggtca
    24541 atcatatcct agctaagcat aatgtgattg atttagaaaa agaaggcatt gctagcatgt
    24601 tatccctagg ctatcgcctg cgagatccca aacatgctca agttcgtaag cctaaagaag
    24661 aagtgatttc agtcgttaaa taaggagatt aaaatgaaag cattacatac ctgtatccgc
    24721 gtcaaagacc ttgaccagtc ggttgctttt tacacaagcg ccttcccttt taaggaaaac
    24781 tatcgtaaag attttccaga tagtcaattt actcttgttt atctgacttt agaaggagaa
    24841 agttatgaat tagaattaac ctacaattat ggtcatggcg actacgactt aggaaatggc
    24901 tatggtcata ttgcccttgg ctctgaacat tttgaagcag accataaaaa acatcgacaa
    24961 gcaggttttc cagttaccga tatcaaagaa ctggctgaca aatctgcccg ctattatttc
    25021 attcaggatc cagatggcta caaaattgaa gtcattgatt taaacaacta atactattaa
    25081 caacagaagc tttaaagctt ctgttgtttt attttttaac ctgacgattg ggacaatctc
    25141 attattaaca gagttttgaa atatctcagc ttttgtgtta caattgccct aaaattccat
    25201 ttgaaagaaa agtctatgac actactatct atcattgtcc cctgctttaa tgaagaagca
    25261 aacattcttc cttattttga agaaatgcat caactagaaa cgtccatgac caaccaactt
    25321 gcttttgaat acatttttat tgatgatggt tctaaggata acaccttggg tattttgcgt
    25381 gagctagcta ctcgctttcc aaatgtgcat tatctgtctt tttcacgcca ttttggcaag
    25441 gaagctggac tcttagctgg actaaaagaa gccaaaggca attacattac tgtgatggat
    25501 gtggatctgc aagatccacc cgaacttttg ccagttatgt acgctaagct aaaagagggt
    25561 tatgacatcg ttggcaccag gcgccaaaat agacaaggag aaccactaat tcgttcaatg
    25621 tgttcgaatc tattttatgg actgatcaaa cacttatcag atactgaaat ggtcaatgga
    25681 gttcgggatt atcggttaat gaccagacaa gtcgttgata gcattcttga gttgggagag
    25741 gttaatcgtt tttcaaaagg gatcttttcg tgggttggtt atcgtatcac ctatcttagt
    25801 tttgaaaacc aaaaacgcaa atatggaaaa agtcgttggc atttttggga gttgctccga
    25861 tattctttag atggctttat caacttttca gaaatgccgt taaccattgc tacctggaca
    25921 gggactttca gctttttgat ttctattttc gccatcttat ttatcattat cagaaagata
    25981 ctctttggtg atcctgtctc tggttgggcc agcactgtct ctattatttt attcatggga
    26041 ggcattcagc tcttttgcat gggtattatt ggaaaatata tttcaaaaat attccttgaa
    26101 actaaaaaaa ggcctctcta tattatcaaa gaaaaacatt aaattaaaac atttttctca
    26161 tcaatcgttt cctactttct gtgcgcgaag ctttcttttt aagcccgtta taccaaatga
    26221 taatgacctt tccaaaatag tatcaccttc cttaacactt taagtagaaa aggaactatt
    26281 aggttgagcc tttttgcaaa tcctagcgac taatgttata atcgtcatac tattgaaaaa
    26341 ggagttcttt atggagtgga ttaaattaat cggtattgtg attatcgtgt tagggtttat
    26401 tttaaaatgt gatgctatcg ctaccgtagt tgttgcagga cttgttaccg cgctggtttc
    26461 aggaatttcg tttatcgatt ttctagatat tttaggaaaa gaatttacca atcaacgttt
    26521 gctaaccatt ttcttcatca ctttaccgct tatcggcttg tcagaaactt atggactgaa
    26581 acaccgagct actcagttga ttcaacgtgt tcaatccctt accgtcggcc gtttattgac
    26641 tctctacctt attattcgag aattagcagg tctcttttcg attcgactag ggggacatcc
    26701 acagttcgtt cgccccttga ttcaacctat gggagaagct gctgctaaag ccaacattgg
    26761 agaagagttg accgatgcag aaaaagatga catcaaagct atggcagctg ccaatgaaaa
    26821 ctttggcaat ttctttgccc aaaatacctt tgttggcgca ggaggtgtcc tacttatcgc
    26881 tggaacttta gaacagcttg gctatgatgg taaccaagct aaaattgcat tttcttctat
    26941 tttaattgct attatctcta ttattatagt tgctatttac aattacctct ttgagaaaaa
    27001 aatggaacgt caacatcaga aaggagataa ctaatggcta acattgcaaa ccttgtttta
    27061 gaaacgatat atatccttat cggcttgcaa ctgtttcaca cagcctactg cacctttaaa
    27121 gataaaacca accctgtcta ttttgggaca gctctgttct ggggattgct gggtgttacc
    27181 ttcgttggcg gtgccttttt gcctaataaa gttatcggtt ttatcgtgat tgtcctagct
    27241 cttttaacct tgtttaagca agttcgtatt ggaacattac cagcctttaa tgaacaaaaa
    27301 gctgaagaaa ttgctcaccg cattggtaac tggattttct taccagttat gttaatggct
    27361 atgatttctc tacttcttgc cttgatcctt cctgatttca gtaaaagtgc cattgggatt
    27421 gctggtatct tagccactat tgctatttta ataatcacta agcaaaaacc atctgctctt
    27481 ttagctgaaa ataatcggat gaaccaacaa gtgtccacaa gcggtatttt gccacagctc
    27541 ttaggagctt taggagctat ttttgcagct gctggtgttg gtgatgtgat tgcttctctc
    27601 attcgggaga ttgtacctgc tgatagccgc ttctttggtg ttctcgctta tgtgcttggc
    27661 atggttattt ttactatgat tatgggaaac gcttttgctg cctttaccgt tattacaacc
    27721 ggtatcggtg ttccttttgt ttttgcttta ggagctgacc ctattattgc cggtgcttta
    27781 gctatgactg ctggtttttg tggtacctta ttaacaccaa tggcagcaaa ctttaatgcc
    27841 ttgcctgttg ctttgatgga gatcaaagat cgaaatgcag ttatcaaaaa gcaagctcct
    27901 atcgcccttg ttttaattat tagtcacatt gccttaatgt atttacttgc ttattactaa
    27961 cttttttgct aagttagtag cgtcagttat tcattgaaag gacattatta tgaaaattct
    28021 tgtaacaggc tttgatccct ttggcggtga agctattaat cctgcccttg aagctatcaa
    28081 gaaattgcca gcaaccattc atggagcaga aatcaaatgt attgaagttc caacggtttt
    28141 tcaaaaatct gccgatgtgc tccagcagca tatcgaaagc tttcaacctg atgcagtcct
    28201 ttgtattggg caagctggtg gccggactgg actaacgcca gaacgcgttg ccattaatca
    28261 agacgatgct cgcattcctg ataacgaagg gaatcagcct attgatacac ctattcgtgc
    28321 agatggtaaa gcagcttatt tttcaacctt gccaatcaaa gcgatggttg ctgccattca
    28381 tcaggctggg cttcctgctt ctgtttctaa tacagctggt acctttgttt gcaatcattt
    28441 gatgtatcaa gccctttact tagtggataa atattgtcca aatgccaaag ctgggtttat
    28501 gcatattccc tttatgatgg aacaggttgt tgataaacct aatacagctg ccatgaacct
    28561 cgatgatatt acaagaggaa ttgaggctgc tatttttgcc attgtcgatt tcaaagatcg
    28621 ttccgattta aaacgtgtag ggggcgctac tcactgactg tgacgctact aaacctattt
    28681 taaaaaaaca gagatatgaa ctaactctgt tttttttgtg ctaaaaatga aagacctagg
    28741 gaaacttttc atcggtcttt ctcaattatc atcttaatct aatactactt ctaacatcag
    28801 cgggtatagt ttgccagtaa ttaagaaacg ttgttgatct aaatgagcaa tcccattcaa
    28861 aacattaagg tcagggtaat gggacttatc aagatttaag gcttttaaca aaggactaat
    28921 atcataggtg gctaccacct ttccagaatc aggttggagt ttgacaatag tattggtttg
    28981 ccaaatattg gcatagagat aaccatctac atactctaat tcgttaagca ttgagatggg
    29041 gacactttct atagcaacta gtacggtatc caataaagca aaatctttgg ggtctcgctt
    29101 ctgcaaaaaa gcatttccac tagtcatcca aagacactgg ttttccttat cataggctaa
    29161 tccccagcca tctccttcaa atggataggc ccctaaacaa ttgcaggtag ccttatcaaa
    29221 cttgtaggct acaccctctt tataggttag taaccaaaaa taatcctcaa caactgttag
    29281 cccttctgca aaaactgtat ctggaaaagc tattttttct gaaaagatct cttgagtaag
    29341 gtcatacacc cctacttttg agaaaccata acgaccggca ctaagtaata tatgactgtt
    29401 gttgagttgt tctaatccct gcgtgtataa gttgctatca taagaataag ttcgtaacaa
    29461 acgaacttgt cctttagtta tcataatact cattcacctt accttgcatt gtagtgtttc
    29521 atttgttttt taatatctct ttcctgatca cggcgtttaa tggtttcgcg tttgtcatac
    29581 tcgtgtttcc ctttagctag accaatcaga actttagcaa agccatcctt gaggtaaact
    29641 ttgagaggaa ctaaggtcat gccagatcct ttaagttcat tttctagatg cgtaatctca
    29701 cgttttttga gcaacagttt gcgggtccgt tcaggatcag cgttccaaat attaccttgt
    29761 tcaaaaggtg caatatgcac gttgaccaac cacgcttccc cattcttaat ttgggcaaag
    29821 ccatctttca gttgaatacg ggctgcacga acacttttaa tctcagttcc cgttaagaca
    29881 atccctgctt caacggtttc aacaatgtga taatcatgtc tagccttttt attttgcgcc
    29941 agtatatgac cttcaccttt tgccatagtt aactcctttt acgactcttc ttttttgctt
    30001 gttctttgta aaatggtttt ttagaccctt ttttagtttt acccttggtt tttgccttgg
    30061 ctacttcttt aggttctttt ttctttatcc ctttagatga ttttgaggat ttacggcgat
    30121 ctcgtcgact agctttatcc gacatcttga ttttttcaac cacatcaaag tcgctaggta
    30181 aatactcaaa gtcaatgtca ccagtttcct tgtcagcctt aaccaatttc acacgaatag
    30241 gttgaccaac tttaaagact ttacctgatt tttcaccttg aaggcttagc gttctttcat
    30301 taaagtgata gtattccggt aagctagtaa tatgaaccaa accttcaatc gtatttggca
    30361 actctacaaa aaaaccaaat ttaacgacac tggccacgat accgtcaaat tcttcaccca
    30421 catactctgc catatactca gcttttttca tggcttcaac cacgcgttca gcatcaatag
    30481 cacgacgctc taactgtgaa gaagatgttg ctaattctgg aatgatctga gtaaaatggt
    30541 cgcgcttttc ttgactaggt tgactgtact cacgaaccat gcggtgaacc aacaagtcag
    30601 ggtaacgacg aatcggactg gtaaagtgag tgtaatattc tgcggccaaa ccgtaatgcc
    30661 catgattatg ttcagaatat cttgcctgtt gcatagagcg taagagcatc atgttaagca
    30721 cttctgctcc tggttgacct tcgacttttg ccataaaggc ttgcaaggct tcctgagaaa
    30781 tcttgttggc tgttccttga atgtgaatac caaaggtgct agcgtaatca ataaattgtt
    30841 gaagtttttc ggcctttggt tcttcgtgaa tacggtagat aaacggtaac ttagcttttg
    30901 caaaatgttc tgccacacac tcattggctg ctagcataaa ggactcaatc atccgctctg
    30961 caattcccct ttgacgaagc accacatcaa ccggcattcc tttgtcatta acaataactt
    31021 tagcttcttg cgtatcaaaa ttcaaggcgc ctcgttttga ccgcatcgtt tccaaaatcc
    31081 tatgcaaagc caccatgagg gtcacatcat cagcaatgct agcgaattct tggagcgctt
    31141 cttcatctcc tgcaatcatg tcattgaccg tactatacgt cattcggtaa gttgtcttaa
    31201 tcactgattg acagatttga taattgacca catacccctg cgggttaatt tccattaagg
    31261 ctgactgggt caaacgatca acgttagggt tcaaagagca gatgccattt gacaaacgct
    31321 ctggtaacat cggaaccaca cgatcggtga catagacaga agtgccacgg gcgatagctt
    31381 ccttatcaag ggaagatcct tctgtcacat aatatgagac atccgcaata tgtaccccaa
    31441 gttcatagtt accgttatcc aatagcttaa tatggatagc atcatctaag tctttggcgt
    31501 ccgcaccatc aatagtaatg gtggtttctt gacgcaaatc cacacggcct attaaatctt
    31561 tagcagttgg tgcttctgaa atagcattgg cctcagctaa aacttctgct gggaactctg
    31621 acacgatatc catcgattca aggacttcta ggacatcaat tccaacgtct ccttgatggc
    31681 ctacgatatc acgcacactg gctacaaaat aatcgtgccc gcgtgtcggg tatttatcaa
    31741 tatcaacctt gatgatttca gtgcctttaa gcacaacagg ctcttttttg atatagattt
    31801 tttgttgaat cttttgattt ttggacctga tataaccagc atattttggt ttgtcatcat
    31861 ctaaaataaa ggttccaaca gctgttttta aagaacgatc aacaatagca acgaccttag
    31921 cttcagccgc tgtgcctttg agacggtctg ctggcttttt aaccactact tcgacagtat
    31981 caccatcaat agcataccca acatcattac gaccgataaa catatcgtct tcattctcat
    32041 ccacatgtaa gaaaccaaag cctgctttat tggcacgaaa aacaccctga acagtaggtt
    32101 cttttttctt ttcacgctct tttctaagag ccagactgcc atcatctgaa aaccgtaaaa
    32161 ggctctgact ttccattttg gaaatggttt taataaggct gggaaaatgc ttagctccag
    32221 ccatctccaa ggccgcagcc aagtcgttca cattggactt gccatgctcc ttgaggtaag
    32281 tcataattct ttctttcatc atacctaatt tctatttctg ttttgtttgt tggaggatat
    32341 caatccgttt cgctgataaa aaaatgagct agactaactc tgtcaagctc actccttatt
    32401 tacttgataa aatggcaagc acaagtgcaa tcgctagcca aaaaaatact agaactgctg
    32461 tgaatcgttg catgaatgct tcaaagccac gagcttttgt acgttcaaac aaggcttctg
    32521 aaccgctgct atcaaaaaca ttgctacttg ggtttttttg aggttgcata aaaatagcaa
    32581 tcacaagcaa taccgacagt actagcaata tcgtaagtag taagttgtac atgttatttc
    32641 ctccactatt gtcatgacca ttctaacaca attcttatca agtttcaaca tgcagggtca
    32701 cttttctctc cttggggcag tatttgggaa cttttatttt ttccggatga ctgcttttat
    32761 ttttactcgt tagataattg ttactgccac actcactgca ttctaaatta atttttactc
    32821 tcacacaata tccttaactt taatatattt tcgaaatata atcaaactcc atattaaatt
    32881 aacaaacaca atcaaactag tcacataaaa aacagaacgg tagcctaaca ctacagccac
    32941 atttgatccg ataaaagggc caatgacttg accaaggtta ctaaacattt gattataggc
    33001 aactactcta gaaatacctt cttttggtgt taacttagtt agtaaagagt taatacttgg
    33061 catcaaagcg cccacaccaa acccataagc aaagcgtagt actcctaatt gaaaactggt
    33121 ctgcgctaag gcactgctaa aatacatgat aaagctataa cacaaagcgg ctaacaataa
    33181 tcgatgattg ccaaatcggt ctcctaattt tcctaagtaa gaactgctaa ataagctaga
    33241 aaaccccatg gccgaaacta ccaggcctga agtaaacatt aagttgtgaa tttgaccaag
    33301 atgacgaata tacaatgata aaatgggggt cactgattga gctgaaattt gaataatcat
    33361 actagtcaca aacaaaccaa gcataatctg gggacttttt acctgtttta aaatgacttt
    33421 tgtaggtatc atctcaaagc gcctaatcgg cttaaactct tctttaacat aaacagctgt
    33481 cattaaagaa cataaaaata atatcacacc aactaataag aaaacttgtc gaattcctaa
    33541 tagctctgcc aaaattcccc ctagtaaagg accaattaaa gcgcctgctg tcactcctgt
    33601 tgctaatgtg cctaaagcat aacctgactc ctcttttggg gcttggctgg caatcaaggc
    33661 agtggcattt ggcacatagc ccgcaaagac acctgttaat aatctcaaaa taagtaacca
    33721 aaacacatta ggaataatag ctaaaccacc catggtaaag gtcatgacaa aacttgctcg
    33781 cagcatcata ggttttcggc cataacgatc agccaacttc ccccaaacag gagcaaataa
    33841 agctgaagca agtgccgtca cagcaactgc cagaccagca tagtattcta ctaattctgt
    33901 cggagtacct aaattttcca catatagagc cataaaaggc ataacaagtg aaaagcttgc
    33961 cccagtaaag aagttaccaa gccaagccac ttttagattt tgtcgccagt tcactgtcgt
    34021 taccgcttta tcactaatag atcatcatct tctttccatt gggcctttga ttattataac
    34081 acatttctgc caaaaacagt atcccataat agtgctaagt ctcatctgat agccttcatc
    34141 gtttacgtaa actacccagt aaacctctga ccagttctcg cccaattgtt ttaaccgtcg
    34201 tactaataaa cgcatctgtt gctttttcga cgactgtttt tcgtggacgc ccaacagaac
    34261 ggcgactagc ttttttggta gctgcttgcg ccttgatggc ttctttagct tctttttcgc
    34321 gttgtgctgt cgctatcgct tcttgggcca gtcggttgtc ttctaaaacc ttagcagcta
    34381 atttttcata agcagagtca cgatcaatgg actgactata tttactggca aaaggtgagg
    34441 actgcacaag ctgctgactt tctatatctg acaaaacagc aaagctactc ttaggcggca
    34501 tgatataggc acgttcaacg atggatggtt gtcccttatc attcaaaaca gaaatcaaag
    34561 cttcgccgac ttctagttct gtaatcaccc ttgccacatc taagtcagga ttttgtcgga
    34621 aagtatccgc agcgacacga accgcctttt gttctttcgg tgtataagcg cgcaaggcat
    34681 gctgaatacg atttccaagc tgagccaaaa ccgtttctgg caaatcaagt gggttttgag
    34741 tcacaaagaa aatcccaact ccctttgaac gaataagtcg cacaatctgt tcaacttttt
    34801 ccaagaaaac tttaggggca tctttgaaga gcaagtgagc ttcatcaaaa aagaaaacca
    34861 tcttaggttt atccaaatcc ccaacttctg gcaataattc gtacagctct gataataacc
    34921 aaagtaagaa ggtcgtgtaa agtgtgggtg attggaaaag cttagtcgct gacaaaatgt
    34981 taatggctcc ataacccgaa gcaacatcta attgcatcaa atcagccacc tctaaagcag
    35041 gctctccaaa aaattgttcg gccccttctt gttccaaagt caagagactt ctttggatag
    35101 ctccgacaga ttgtttggtc acattaccgt aatggctgga atagtctgag gcatggtcac
    35161 caacttcttt tagaatggcc tgcaagtctt tcaaatcaat caaaagccaa cctttctcgt
    35221 cggcgatttt aaagacgatg tttaagacac ctgtctgggt atcattaaga ttcaataaac
    35281 gcgacaacat catcggtccc agctcagaaa tcgttgtccg taagggttga ccgttttgac
    35341 caaaaacatc ccacattctt acaggaaagg cctgaggctg gtaatcactt acccctattg
    35401 tggctaaacg cgcagccaat ttatcagtca cctctcctgc tttagtaaga ttagacaggt
    35461 ctcctttgat atctgccaaa aagactggca caccagctaa acttaattgc tctgctagca
    35521 cttttaaggt cacagtttta cctgttccag tcgctccagc aatcaaaccg tgacgattta
    35581 gcatccctaa ttgtaaggct atcggttgat tgccttttgc aattgtcatt gtagtcatag
    35641 gcttcctctt ttttgatgat catacttgtc gatatgtgtt tacccataag ttaaagtgtt
    35701 tagaagggtc tcgctcttaa tattattata acatatagcc cttgatgcgc taatttaaaa
    35761 gggaccagct agttttagac agaaatagct tgattttgac agctatgata cgaatctctc
    35821 agcttagcta cctcggattg gctaatgaca acaacgcaga ttgtacttgc tttattaagg
    35881 ctgcaatatc cccactatta tcaatcacta gactggcata gggctttttt tcctctattg
    35941 gtaactgact ggctattcgc tgccttgctt ttcctttgtc taaacgattt ctagccatta
    36001 agcgctgcaa ttgtgtctga gcatctacat aaaccagcca aatcgcatca aaccagtctt
    36061 ggtagcccaa ttccattaaa aggggaatat ccatgaaaaa aatggcttgg ctctgtgcta
    36121 agtggtcacg cttagccgcc aattcttcct taatgatttg attttgaatg gctgaggatg
    36181 ttgccatatt atctgggttt gaaaaaagca tttctgacag ctttgtgcga tctaactcac
    36241 catctgtttt taaaatctga ttcccaaaag cttctctaag agcctcgtaa aggcgaccgc
    36301 ctttttcttg caagtcatgg accacttgat ccgcatcaat cacctgataa ccagcttttc
    36361 taatgacctt aaccacagtc gattttcctg atgcaatgcc tcctgtgatg ccaataatca
    36421 tggtcttttt ttctggcatt ttggacaaat gtgcgtcccc cttcctccaa cttttaattt
    36481 gacaatatcc tgtccacaac gaggacacga tttcccagtt tgaccataaa cctgcaaata
    36541 gtcctgcata gtgccatcag ctcccaaagc attacggtaa gtacggacgg tcgaaccgcc
    36601 ctttttaatt cctaaagcta ggattcgtat ggtttcatca tgcagccgtt ttatctccgc
    36661 cttattcaac ctagaagacg cagtttctgg atgaacctta gcagcccaaa gtacctcgtc
    36721 cacataaata ttccctaaac cagcaaccaa ggtctggtct aacagatgtg gttttatggg
    36781 tttttgggag gatagcaaag cagcctcaaa ggtttttaac ttaaagatct ctttctttgg
    36841 ttcagggcct agttttcgtt tggcaaaaaa cgctgataat tgagattttg ctatcaaatc
    36901 aaaggttcca aatttacgca catcttggta aaccaaggtc gaaccatttt tcaattcaaa
    36961 aaagacatga aagtgtttgt tatcagggac ctcatctgga aaaagcaaat atttgccttc
    37021 catccgcaaa tgtgatacca acactaattg ccccaaatca attaataaat attttccccg
    37081 acggccaact gactgaatga tttgaccagg tagggtcagg gcaaacgtct ctaagtcggt
    37141 tttaaccatt tttggcactt taagcgtaac agccacaatt tcttggccaa gcactaaagt
    37201 ctcaagccct cgtcggaccg tttcaacttc tggtaattct ggcataatcc attatttaaa
    37261 ggacagctag accctttgct gctacaaaga ataaactcag cataaaaaag tcactcaata
    37321 gactcaggtc taggctactg actgcgtttc aaaaaacaca gctgtccttc tcctttctta
    37381 tttcttattt tacgaataca tctgatagaa agcaactcat aaatctgcct cagaccagtc
    37441 ctcatccccc ttacctccca gcactatttg gcggtaatgt tccttataac tataatacaa
    37501 tgagtcctct ccaagatact taaaaatctg caaggcctgc cgcatgtcct cttctccaga
    37561 catttcttcc tgctttaatt tataataccc atgcacatat aagaaaacag tcttttcata
    37621 aaaattgagc tcgtctcgca gcaaaagatc aattttgtta atcaaatagc gactatgttc
    37681 aaagcaagaa tggtcaatac tgataatgag acaattaatg gataactgag tcactaacat
    37741 tttattggtt ttattttgtt ccgaataagc aaaagatgct accatttcct tagtcaataa
    37801 aaatagggta ttgtaattca tgaagcgcga gcaattcccc agaagaatga tctcataata
    37861 tccccactgt tccactttaa ataaataatc tgtgaggcga gtcaattctt cttgactagg
    37921 tgcaattgag gagtcaatag aaaaaagaat agctttaatc atcgttcgtt cataatcttt
    37981 atgagcataa tccttcaaca gtttggtcaa tttaaccacg tttttctcag cataacattt
    38041 tctcgcctga cttaagagcg tgaaaaaatg cgtatgcgtc ttggaatgag ccgaaacaaa
    38101 ttcgtcaatc gtaatattca gtttatccaa aagattaagc aagcgactgc aggtgatttc
    38161 tgattcccct cgttcaaatc ttgaaatttg tgacttggac aggtattcat ctgctaaaaa
    38221 agaaatgcta acctgcttac ccttacgtaa tcgccttaag gtttttccga gttctttttc
    38281 catttttccc actttcacaa caaaaaatta aaatctgcta aatccattat ataatacaag
    38341 tacaaaatag aaaatcagaa aggagacagt catgaaaaaa gttaataaag ctttgctttt
    38401 tacattgatc atggatatcc tgattatcgt tggtggataa cctttcgctt aaaaacaatc
    38461 cacttttggg aaacccttat atttagtttg taacaggaaa actaataaat attaaaaaga
    38521 gtgttagcga cctagcggca gctttactct taagtgcgtt tgctgccatt gacagcaagg
    38581 tcaaagctga tgaaacagca ggggcatacc gttatgatgt gtctgaacaa aacacttact
    38641 atcaaactat cagctccatt aaccagcaac gacctggtgc cactctcgac gaatgaggtg
    38701 attattatgg aacccttact tcatttactt cccaaagtcg taccagtact tatacacttg
    38761 gtagacaaag ccaacgtatc atggttaaca gtgatattac agttacctat actcttaaag
    38821 acaatttggt agcccttcat aaggaatata aaacctttgt caaaaaaata ttacagataa
    38881 accgatcacc agtgactacg acaaggctaa ggttatttat aaccatttaa tcaacgaata
    38941 cacttacgcc acaaaataac ttagcaccaa tcgcaaaacc gtaagcagca tcaacaatca
    39001 tactcctaaa gctctttatc gtggcaagtg tggtgtttgt caagcttatg ccgtcgtgtt
    39061 taaagatatg gcagaagctg caggcttatc agcttggtat gtgataaaaa aggattgaat
    39121 gagcaccatg cttgaaacat cgttaccatt catggtgtta attcctacgt tgatgctacc
    39181 tggaatgatt cagcatacac cacaaggtat ttccttgctg gaaaagacgt gaggaatact
    39241 gagtaccgtt tagatagcca gtacaaccac ttggctaatg ctattttaaa taccagctac
    39301 taaaaaggct aaactaacaa caactacatt tttcaactag aaaggcctaa acaatgacca
    39361 aaaaacagtt ttatcttatc ttagctatta gcatactgtg ttttattctt gccgtcagcc
    39421 ctaaaccacc aattcctaaa cacactattg aaaggaaaag gactgcgatg accataggcc
    39481 actcaaaaca aaaccctcac aaaaaagaag cccttaaaca caaaaaaaat aaaaataagg
    39541 ctctatttct tccaagtggg gacagcgcta tcaaatctgt tattagcatg acagttagac
    39601 tcctgttaga tgaccaatct tagctctcct aaaattagtg gacactacca tttcggtagt
    39661 gttctttttt aagctaatct catcaccacg ctttcttcaa gctaaaaaac tgatcatgaa
    39721 agagcaaccc catcacccta acagcccact ttgcccgcac tttcttaaaa agttaggaga
    39781 aaacgatata ccaattattt tctgatccca gctccctatc attaacaaga tgtgtagcac
    39841 ggacctacat acaggtaagc tagagtcatt ctcgctattt cggacaaaaa gaggccggta
    39901 gttccctgac ctcttcttta tttatcttgt aacactcctc ttcttagcga gacttactag
    39961 cacataattc ttaagcactc ttatcattta gactaggaat aacaccatct gaatgaagca
    40021 aatgatgcgc cagatctgcc agagtatcat ctccataagt aatccctgtt tggtgctgtt
    40081 tctgatgaaa atcagatgac tccttaactt tagcagtcac ctgctggtca cttggatgaa
    40141 aattaatttc tctcttggct tcagccgcaa ctggctcgag gaacaactta ttgacattac
    40201 ggtcttcctc caaatgatta aggatagcag catcatcttc taacgaaaga accttcttgg
    40261 gtaacaaaaa ggggttattt agccttggct cagtaacgac ttccttggct actcgtgata
    40321 gtttattatt gtcttcctca ggtatcaaac ggttaggcaa tcgatgcaat tcttccggct
    40381 gtgaggcgct cacagctact tcagaagaaa cctccaagcc ctttcctgtt tgcctgtcta
    40441 aagcaaccgg caaattatta actaactttt taacctgtcc tcagcgctca tttcaacact
    40501 aggaagagct gtcgctggtt ctagccagct accaacttct gctggtctta ccttaacatc
    40561 gctggcaggc ttctccttct catcttcatt aggtctaaaa ggctcaaacc gccctgttga
    40621 tttttcatct atgaccttta tattgtcttt tactacatga gacagtggtt cgacatttac
    40681 catagcttca tgctcgttaa ggctctggtc tcgtttgaat ttaccaggaa taccaggagt
    40741 cggtgttccg acagattgat cggcttcagt aggctctttt acggagcctt ttttccataa
    40801 aactgctgga ggaataatat ccgtagagcc agccccataa gtaatcgtgg ccagcccccc
    40861 ctttggatta atagatactt taatattgtc cggtaaggct ccactacctc ctgtggttaa
    40921 aagggcaccc gcatttttaa tgagagttgt cattcgttca ataccagcaa cgccaatatg
    40981 gttcaagtca tctactggta actgatcaac agatttcatg gtgtatttcc aagcttgcgg
    41041 ttgaacaaga aaaacagttc ctttatacat tgtgttatgc atatcatcaa tgactttgaa
    41101 ataccttata tatttggttt gtacattagg gttagcaacg ggaacagtgc tttcaggaac
    41161 tcctgacatc gtaaaaatcc ctctagcaga agtttgaaag ccctcataaa catgacccat
    41221 accaggaaca gtctgagcgg tcaaagactt atcagaacca tccaaagcaa tgcgaatatc
    41281 tttcatcaga tacatctgat tggtgtaggt aaacctaacc gtgttagcct cacctcgata
    41341 caataccacc tgggagggct gatccgaaga aaactgagag gttgtttctt ccttatagcc
    41401 aactccaaaa cgtctatcag acgaatggac tgaatctgcc gcaactgtac cactcaaact
    41461 gactagtaaa gtagccgcac aaccaactaa taaactgctc gttttaactt taacatctct
    41521 taacatcatc atgttccttt cattattttt tatttaggaa ttcgtcatac tatattttct
    41581 catattagtc taacaaaaaa ctcgtaattc tatataaatc atataaaatg acgagttttg
    41641 gcaaagatga gtatagcagg atagaagaca gattatttct gaaacttcaa aggtatcttc
    41701 ttgtcacgaa ctattcttta attgaatcgg ttacactaaa ctagtcccat tatttaaaaa
    41761 caaacttt
//
LOCUS       DAUCXI010000015        40464 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.015, whole genome shotgun sequence.
ACCESSION   DAUCXI010000015 DAUCXI010000000
VERSION     DAUCXI010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40464
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.015"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            18..98
                     /locus_tag="VGY43_000792"
     tRNA            18..98
                     /locus_tag="VGY43_000792"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="VGY43_000793"
     tRNA            105..175
                     /locus_tag="VGY43_000793"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="VGY43_000794"
     tRNA            187..259
                     /locus_tag="VGY43_000794"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="VGY43_000795"
     tRNA            268..339
                     /locus_tag="VGY43_000795"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            359..442
                     /locus_tag="VGY43_000796"
     tRNA            359..442
                     /locus_tag="VGY43_000796"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Leu,seq:caa)
     gene            1525..1833
                     /locus_tag="VGY43_000797"
     CDS             1525..1833
                     /locus_tag="VGY43_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEQ4301999.1"
                     /translation="MKHRFQVKRGVSVYLEKRIPMCAGMGGGSSDAVTIRALNQLWLL
                     TLSRKDMMDIGIPIGSAVPYCLLSGCAQVTGKGEVVCRILGLLSSWVVLVKPDFGIST
                     "
     gene            1888..2100
                     /locus_tag="VGY43_000798"
     CDS             1888..2100
                     /locus_tag="VGY43_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEQ4302000.1"
                     /translation="MVAAIEAGNYNDGILTEMNNLLEDIFIAKRPFIQKIKEKTLQAG
                     AATTLMTGSGPTVFALCQTEKQTIIV"
     gene            2210..2653
                     /locus_tag="VGY43_000799"
     CDS             2210..2653
                     /locus_tag="VGY43_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEQ4302001.1"
                     /translation="MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKVLNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2657..3376
                     /locus_tag="VGY43_000800"
     CDS             2657..3376
                     /locus_tag="VGY43_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302002.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEAETDDEKGGHGHA"
     gene            3369..4184
                     /locus_tag="VGY43_000801"
     CDS             3369..4184
                     /locus_tag="VGY43_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ4302003.1"
                     /translation="MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVIGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLF"
     gene            complement(4224..4607)
                     /locus_tag="VGY43_000802"
     CDS             complement(4224..4607)
                     /locus_tag="VGY43_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEQ4302004.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEVRYDLIDLQAALVAKLEQHLPISGVTSVSNDKELMEEGTHFHLHLIPRL
                     TNDSFWESITINQENWDLTPFLKHL"
     gene            complement(4658..5914)
                     /locus_tag="VGY43_000803"
     CDS             complement(4658..5914)
                     /locus_tag="VGY43_000803"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEQ4302005.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSIDNHNIVEILVAAKISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LNNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            6006..8318
                     /locus_tag="VGY43_000804"
     CDS             6006..8318
                     /locus_tag="VGY43_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEQ4302006.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQEHKGVVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLYNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTLGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADPNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8582..12148
                     /gene="rpoB"
                     /locus_tag="VGY43_000805"
     CDS             8582..12148
                     /gene="rpoB"
                     /locus_tag="VGY43_000805"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ4302007.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            12239..15862
                     /gene="rpoC"
                     /locus_tag="VGY43_000806"
     CDS             12239..15862
                     /gene="rpoC"
                     /locus_tag="VGY43_000806"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEQ4302008.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDGLEINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAE"
     gene            16014..16379
                     /locus_tag="VGY43_000807"
     CDS             16014..16379
                     /locus_tag="VGY43_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEQ4302009.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            16472..17410
                     /gene="tadA"
                     /locus_tag="VGY43_000808"
     CDS             16472..17410
                     /gene="tadA"
                     /locus_tag="VGY43_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEQ4302010.1"
                     /translation="MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQEA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYVRLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            17394..18381
                     /locus_tag="VGY43_000809"
                     /pseudo
     CDS             17394..18381
                     /locus_tag="VGY43_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
     gene            18383..18709
                     /locus_tag="VGY43_000810"
     CDS             18383..18709
                     /locus_tag="VGY43_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEQ4302011.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18684..19112
                     /locus_tag="VGY43_000811"
     CDS             18684..19112
                     /locus_tag="VGY43_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEQ4302012.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP"
     gene            19117..19353
                     /locus_tag="VGY43_000812"
     CDS             19117..19353
                     /locus_tag="VGY43_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ4302013.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEMTLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            19346..19780
                     /locus_tag="VGY43_000813"
     CDS             19346..19780
                     /locus_tag="VGY43_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEQ4302014.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD"
     gene            19764..20090
                     /locus_tag="VGY43_000814"
     CDS             19764..20090
                     /locus_tag="VGY43_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEQ4302015.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVFFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            20188..21141
                     /locus_tag="VGY43_000815"
     CDS             20188..21141
                     /locus_tag="VGY43_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ4302016.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN"
     gene            21200..22396
                     /locus_tag="VGY43_000816"
     CDS             21200..22396
                     /locus_tag="VGY43_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEQ4302017.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGEISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22583..22891
                     /locus_tag="VGY43_000817"
     CDS             22583..22891
                     /locus_tag="VGY43_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302018.1"
                     /translation="MYVFIEPNDLKDYLITVYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLTIRDLVSYKLALIFAYLYLIIRSLVAKKMEALGKITTNSQKPPFDTSQVLC
                     "
     gene            complement(22974..23744)
                     /locus_tag="VGY43_000818"
     CDS             complement(22974..23744)
                     /locus_tag="VGY43_000818"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEQ4302019.1"
                     /translation="MKIGIIGIGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLA
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRDLTDSFGSTFDISEKDFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTTTVSSAIDKTIDKAKSL"
     gene            complement(23792..24859)
                     /gene="pepA"
                     /locus_tag="VGY43_000819"
     CDS             complement(23792..24859)
                     /gene="pepA"
                     /locus_tag="VGY43_000819"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEQ4302020.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPHIEDIVFDGGFTDKAEAERFGITPGDI
                     IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEEAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKCY"
     gene            25315..25608
                     /locus_tag="VGY43_000820"
     CDS             25315..25608
                     /locus_tag="VGY43_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEQ4302021.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRQRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDKG"
     gene            25605..25922
                     /locus_tag="VGY43_000821"
     CDS             25605..25922
                     /locus_tag="VGY43_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEQ4302022.1"
                     /translation="MIRPTSYESLAALIEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFVCVNRDQFIEVAQKWDIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            25940..26566
                     /locus_tag="VGY43_000822"
     CDS             25940..26566
                     /locus_tag="VGY43_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEQ4302023.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEASSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQIV
                     EMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELALPNAPQKRGIIELDESAVVGEAFDLAKHWKG"
     gene            26718..27113
                     /locus_tag="VGY43_000823"
     CDS             26718..27113
                     /locus_tag="VGY43_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEQ4302024.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISVVVWGKLAETLVSYASKGSLMSIDGELRTRKYDKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(27373..28014)
                     /locus_tag="VGY43_000824"
     CDS             complement(27373..28014)
                     /locus_tag="VGY43_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEQ4302025.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
                     HQVHGEYPAWYEDYKVSPKMKIDGNSLDFVQNPQDLATVLKMIDTKLKELHLL"
     gene            complement(28034..29011)
                     /gene="dusB"
                     /locus_tag="VGY43_000825"
     CDS             complement(28034..29011)
                     /gene="dusB"
                     /locus_tag="VGY43_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEQ4302026.1"
                     /translation="MIKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELADLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFETVR"
     gene            complement(28998..29870)
                     /gene="hslO"
                     /locus_tag="VGY43_000826"
     CDS             complement(28998..29870)
                     /gene="hslO"
                     /locus_tag="VGY43_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEQ4302027.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPGASEEEIARYEKRLQEMPAISHLLASKNHVDSLLEAIY
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNESDLEALINDKA"
     gene            complement(30017..31510)
                     /gene="rofA"
                     /locus_tag="VGY43_000827"
     CDS             complement(30017..31510)
                     /gene="rofA"
                     /locus_tag="VGY43_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HEQ4302028.1"
                     /translation="MIEKYLESSIESKCQLIILFFKTSYLPITEVAEKTGLTFLQLNH
                     YCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALIPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSHDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRDLNHKHFHLFCHYVEQILRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVQHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTKQLT"
     gene            31777..33669
                     /gene="sfbI"
                     /locus_tag="VGY43_000828"
     CDS             31777..33669
                     /gene="sfbI"
                     /locus_tag="VGY43_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein SfbI"
                     /protein_id="HEQ4302029.1"
                     /translation="MNNKMFLNKEAGFLAHTKRKRRFAVTLVGVFFMLLVCAGAIGFG
                     QVAYAADEKTVPNRINSNPEFPWYGYDSYSGRLLRYHNLKVNLNGSKEYQAYCFNLKR
                     FEPKKEESSSPNWYKKLDGSTETFKKYAENPRFSGEELRRHILKVLYNGYPNSNEIMK
                     GIDPLNAILVTQNAIWYYSDSAPINDINNFFTSEANDLNIPPQQLTLMREALRKLISS
                     DENLVKQVPSNFKLSIFESSDKSYQNLLSAEYVPDDPPKPGDTSEHNPKTPELDGTPI
                     PEDPKRPDESSEPALPPLMPELDGEEVPEVPSESLEPALPPLMPELDGEEVPEVPSES
                     LEPALPPLMPELDGEEVPEVPNESLEPALPPLMPELDGQEVPEVPSESLEPALPPLMP
                     ELDGEEIPEVPSESLEPALPPLMPELDGQEVPEKPSVDLPIEVPRYEFNNKDQSPLAG
                     ESGETEYITEVYGNQQNPVDIDKKLPNETGFSGNMVETEDTKEPEVLMGGQSESVEFT
                     KDTQTGMSGQTTPQVETEDTKEPGVLMGGQSESVEFTKDTQTGMSGFSETVTIIEDTR
                     PKLVFHFDNNEPKVEENREKPTKNITPILPATGDIGNVLAFLGILILSVLSIFSLLKN
                     KQNNKV"
     gene            33957..34805
                     /locus_tag="VGY43_000829"
                     /pseudo
     CDS             33957..34805
                     /locus_tag="VGY43_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407229.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
     gene            35091..37361
                     /locus_tag="VGY43_000830"
     CDS             35091..37361
                     /locus_tag="VGY43_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus ancillary protein 1"
                     /protein_id="HEQ4302030.1"
                     /translation="MNNKKLQKKQDAPRVSNRKPKQLTVTLVGVFLMFLTLVSSMRGA
                     QSIFGEEKRIEEVSVPKIKSPDDAYPWYGYDSYDSSHPYYERFKVAHDLRVNLNGSKS
                     YQVYCFNINSHYPNRKNAFSKQWFKRVDGTGDVFTNYAQTPKIRGESLNNKLLSIMYN
                     AYPKNANGYMDKIEPLNAILVTQQAVWYYSDSSYGNIKTLWTSELKDGKIDFEQVKLM
                     REAYSKLISDDLEETSKNKLPQGSKLNIFVPQDKSVQNLLSAEYVPESPPAPGQSPEP
                     PVQTKKTSVIIRKYAEGDYSKLLEGATLRLTGEDILDFQEKVFQSNGTGEKIELSNGT
                     YTLTETSSPDGYKIAEPIKFRVVNKKVFIVQKDGSQVENPNKEVAEPYSVEAYSDMQD
                     SNYINPETFTPYGKFYYAKNKDKSSQVVYCFNADLHSPPESEDGGGTIDPDISTMKEV
                     KYTHTAGSDLFKYALRPRDTNPEDFLKHIKKVIEKGYNKKGDSYNGLTETQFRAATQL
                     AIYYFTDSTDLKTLKTYNNGKGYHGFESMDEKTLAVTKELINYAQDNSAPQLTNLDFF
                     VPNNSKYQSLIGTEYHPDDLVDVIRMEDKKQEVIPVTHSLTVKKTVVGELGDKTKGFQ
                     FELELKDKTGQPIVNTLKTNNQDLVAKDGKYSFNLKHGDTIRIEGLPTGYSYTLKETE
                     AKDYIVTVDNKVSQEAQSASENVTADKEVTFENRKDLVPPTGFTTDGGTYLWLLLLVP
                     FGLLVWFFGRKGLKND"
     gene            37354..37875
                     /gene="lepB"
                     /locus_tag="VGY43_000831"
     CDS             37354..37875
                     /gene="lepB"
                     /locus_tag="VGY43_000831"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ4302031.1"
                     /translation="MTNYLNRLNENPLFKAFIRLVLKISIIGFLGYILFQYVFGVMIV
                     NTNQMSPAVSAGDGVLYYRLTDRYHINDVVVYEVDNTLKVGRIAAQAGDEVNFTQEGG
                     LLINGHPPEKEVPYLTYPHSSGPNFPYKVPTGTYFILNDYREERLDSRYYGALPINQI
                     KGKISTLLRVRGI"
     gene            37897..38940
                     /locus_tag="VGY43_000832"
     CDS             37897..38940
                     /locus_tag="VGY43_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QVPTGV class sortase B protein-sorting
                     domain-containing protein"
                     /protein_id="HEQ4302032.1"
                     /translation="MKKNKLLLATAILATALGTASLNQNVKAETAGVVTGKSLQVTKT
                     MTYDDEEVLMPETAFTFTIEPDMTASGKEGDLDIKNGIVEGLDKQVTVKYKNTDKTSQ
                     KTKIAQFDFSKVKFPAIGVYRYMVSEKNDKKDGIRYDDKKWTVDVYVGNKANNEEGFE
                     VLYIVSKEGTSSTKKPIEFTNSIKTTSLKIEKQITGNAGDRKKSFNFTLTLQPSEYYK
                     TGSVVKIEQDGSKKDVTIGTPYKFTLGHGKSVMLSKLPIGINYYLSEDEANKDGYTTT
                     ATLKEQGKEKSSDFTLSTQNQKTDESADEIVVTNKRDTQVPTGVVGTLAPFAVLSIVA
                     IGGVIYITKRKKA"
     gene            38956..39681
                     /gene="srtB"
                     /locus_tag="VGY43_000833"
     CDS             38956..39681
                     /gene="srtB"
                     /locus_tag="VGY43_000833"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HEQ4302033.1"
                     /translation="MMMTIVQVINKAIDTLILIFCLVVLFLAGFGLWDSYHLYQQADA
                     SNFKKFKTAQQQPKFEDLLALNEDVIGWLNIPGTHIDYPLVQGKTNLEYINKAVDGSV
                     AMSGSLFLDTRNHNDFTDDYSLIYGHHMAGNAMFGEIPKFLKKDFFNKHNKAIIETKE
                     RKKLTVTIFACLKTDAFDQLVFNPNAITNQDQQRQLVDYISKRSKQFKPVKLKHHTKF
                     VAFSTCENFSTDNRVIVVGTIQE"
     gene            39698..40285
                     /locus_tag="VGY43_000834"
     CDS             39698..40285
                     /locus_tag="VGY43_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HEQ4302034.1"
                     /translation="MRKYWKMLFSVVMILTMLAFNQTVLAKDSTVQTSISVENVLERA
                     GDSTPFSIALESIDAMKTIEEITIAGSGKASFSPLTFTTVGQYTYRVYQKPSQNKDYQ
                     ADTTVFDVLVYVTYDEDGTLVAKVISRRAGDEEKSAITFKPKRLVKPIPPRQPDIPKT
                     PLPLAGEVKSLLGILSIVLLGLLVLLYVKKLKSRL"
BASE COUNT        12571 a         7158 c         8601 g        12134 t
ORIGIN      
        1 aaaatttaat attttacgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgtgggtt cgaatccctc tctttccatc ctaaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttaga
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttaaatttta tatttaaagc
      361 cggcgtggcg gaattggcag acgcgctgga ctcaaaatcc agtgtccgca aggacgtgcc
      421 ggttcgaccc cggccgccgg tatacttgaa aaacaaggtt tgtaaacctt gttttttgtt
      481 ttgatcttag gctgtagcta cgtagtacaa tctcttatat tactgataag gtctatttaa
      541 tgcgcaagat ttgtggtatg atgaatatga ttgagtattg atgctttatg ggattaccgg
      601 taaggttttt aaaaaggttt gtcactacta ggtgcttttt taactataga aagacagtta
      661 tggattgatg tattgtaact aatgttggag gttaatggtg gttgagtttt gagatattta
      721 cactgataat cgggtggaaa ctggtcgggt atcgggtaat ggagtgtggt tcttcgttta
      781 agcaaggaga ttatcgtttg gtggttcata tttgcttgtt aaatgttagg gatgagatgc
      841 tgagtcagca aggccatgaa gataaagctg actggctaga gccttgagat gtgacgtttg
      901 gtggaagtcc tttttggtga gatggcacag catatagtaa tattagatcc tgaggaagaa
      961 ttgggacttt cattaggctt gactggggta tgacctcact ttacaattca tttcgatgat
     1021 gggtttgatg atacgttttt agttcaagac tttgtagagt tggagaattt ggttctttat
     1081 gaggaagaag tgcaggtaat tcgttgagcc agtcgtgaag atattttagg tatgattgat
     1141 gaaggttcgt tcattcctta tctgaagtat aaaataaatt tgtgctttga gatggttggt
     1201 caatataaag tccatcaatc ttagaagtaa taatttttga attttttctg aggtttgtgt
     1261 atatttgata gtgtactgat gtaagaagta aggagtacta tgatggcaat caatgagaga
     1321 gcttctgcaa aaatcaagtt aggccttgat actaagaata agcgatgaga tggttaccac
     1381 gatttatcga aggttatgat gagtattgat ctgtgtgact atgtgacggt tgaccatata
     1441 gatgacaata agattgtctt tgcctcaaac tgtccgaaaa tacctattaa ctaagataat
     1501 gatgtttata agatagttca gctaatgaaa catcgatttc aagttaaaag aggagtttcc
     1561 gtttacttgg aaaagcggat tcccatgtgt gctggtatgg gaggaggttc tagcgatgct
     1621 gttactatca gagcattaaa tcagttatgg ctccttactc ttagccgaaa agatatgatg
     1681 gatattggta taccgattgg tagtgctgta ccttattgct tgctttcagg ttgtgcccaa
     1741 gttactggta aaggtgaagt ggtttgtcgc attttggggc tgttatcgtc ttgggtggtt
     1801 ttggttaaac cagattttgg tatctcaact tgaacaattt ttctagatat taattgtaaa
     1861 accatttcaa gagtgtctac tactcatttg gttgcggcga ttgaagcggg taactataat
     1921 gatgggatat tgactgaaat gaacaatttg ctggaagata ttttcattgc caagcgaccc
     1981 tttattcaaa aaataaaaga gaaaacactg caagctggtg ctgctactac tttgatgaca
     2041 ggaagtggac cgactgtttt tgctttgtgc cagaccgaaa aacaaactat aatagtttaa
     2101 aaggactttg caaggaagtt tttaaggtga gaatgttgta atattttgtt gggattgctt
     2161 ctttggaagc ttcatgttat aattaactgg ttaatgaaag aggagattta tggggacttt
     2221 agaaaaaaaa cttgataact tagtaaatac tattttatta aaagcagaaa atcagcatga
     2281 gttattattt ggagcttgtc aaagtgacgt taagcttact aatacgcaag aacatatttt
     2341 aatgttacta tctcagcaac gtctcactaa tacagatttg gctaaggtat taaatattag
     2401 tcaggcggca gtaactaagg ctatcaagag tttggtcaaa caagacatgc tagcaggaac
     2461 taaggatacg gttgatgcta gggtgactta ttttgaatta accgagttag ctaagcctat
     2521 tgcatcagaa catacccatc atcatgatga aactttaaat gtttacaacc gtttattaca
     2581 aaaattctct gcgaaagaat tagagattgt agataagttt gtaacagttt ttgctgagga
     2641 attagaaggg taatccatga gatacatatc agtgaaaaat ctctcctttc aatatgaaag
     2701 tgagccagtt ttagaaggga tcacttatca tttagatagt ggagaatttg tcaccatgac
     2761 cggtgaaaat ggcgctgcaa agtcaacctt aataaaagca accttaggaa ttttacaacc
     2821 aaaggctgga cgagttacta ttgctaaaaa aaataaagac ggtaaacaat taaggattgc
     2881 ttacttgccg cagcaagtag ctagctttaa cgctggtttt ccatccaccg tttacgagtt
     2941 tgtcaaatca ggtcgctacc cacgtagtgg ttggtttaga catttgaaca aacacgatga
     3001 agagcatgta caagcaagct tagaagcagt cggcatgtgg gaaaaccgtc ataagagaat
     3061 tggtagttta tcaggtggtc aaaaacaacg tgtggttatt gcccgtatgt ttgcttctga
     3121 ccctgatatt tttgtgctag acgagccaac aacgggaatg gatagcggta ctactgatac
     3181 cttttatgaa ctgatgcacc acagtgcaca tcaacatggg aaatccgttc tgatgattac
     3241 ccatgaccca gaagaagtga aggcttatgc tgatcggaac attcatttag tcagaaacca
     3301 aaaacttcct tggcgttgtt tcaacattca tgaagctgaa acagatgacg aaaaaggagg
     3361 tcatggtcat gcttgatatt ttatcctatg atttcatgca acgggcggta atggcggtag
     3421 ttgccattag tatttttgct ccgattttag gtattttcct tattttacgt cgtcaaagtt
     3481 tgatgagcga tacccttagt catgtttctt tggctggggt agcgcttggg gtagtcattg
     3541 gtatttcacc aaccatcact actattattg ttgtggtttt agctgctatt ttgttagaat
     3601 acctgcgtgt agtttacaaa cactacatgg agatttcaac ggcgattttg atgtcacttg
     3661 gcttggccct atctctgatt attatgagta agtcgcatag ttcatcaagc atgagtttag
     3721 aacaatacct ttttggatcg atcatcacga ttagtatgga acaagttgtc gccttgtttg
     3781 ctattgctgc gattatttta atcttgaccg ttctcttcat tagaccgatg tacattctga
     3841 cctttgatga agatactgct tttgtagatg gtctgcccgt tcgcttgatg tctgttctat
     3901 tcaatatcgt cactggggtt gctattgctt tgaccattcc agcagcagga gcacttttgg
     3961 tttctaccat tatggtcttg ccagcaagta tcgcaatgag attgggtaaa aactttaaaa
     4021 cagttatctt actgggaatt gtcatcggtt ttagcggtat gttatctggt attttcttat
     4081 cttatttctt tgaaacgcca gctagtgcca ctattaccat gattttcatt agtattttcc
     4141 tcttagttag tctaggtgga atgcttaaaa aacggttatt ttaataagaa aaatcctcac
     4201 atgtttaaca tgtgaggatt tatttataaa tgctttaaaa agggggtaag gtcccaattt
     4261 tcttgattaa tggtgatgct ctcccaaaag ctatcattag ttaaacgagg aatcaaatga
     4321 aggtgaaaat gagtcccctc ctccatcaac tccttgtcat tgctgacgct agtgacgcct
     4381 gaaatgggaa ggtgctgctc tagcttagca actagagcgg cttgtaagtc gatgagatca
     4441 tagcgcactt cctttggtag ttgtgttaga ctagtgtaat ggtctttgga aatcagtaaa
     4501 aggtgcccct tttggatagg atcaatatca aaaacaacct tgaaatattg actttgagtc
     4561 agtagctgat ttgctttgag ctgatggcaa aagatacatt ctgtcatagg tacatctcct
     4621 tatgaaaaaa cgagccagag ctcgtttaat cggttatcta gtaagtgaga acagcgtatt
     4681 ttttcttacc gcggcgaata acggttaatt gatcatcaat tttatcatca ttatttaatt
     4741 ggtaatctaa atcttgaacg cggtctccgt taatgtagat tgctccattt tgcacgtctt
     4801 cacgcgcctg gcgttttgat ggggaaatct tagcagctac taaaatctcg acaatattat
     4861 gattgtctat tgattgaacg tgataatttg gtacattgct caatccttgt tttaattcat
     4921 tagcagaaag atttttgatg tttccagcaa ataactgctc ggtaatgtta agagcttgtt
     4981 tataagcttc ttcgccatga accaaggtaa ccacttcgcg tgccaaggtt ttttgagcga
     5041 gacgctcgtg acgagcggca ttaaattgag tttcaatttc tgcaatctca tctagagata
     5101 agaaggtgaa gattttcaag aaacgcactg catcatcatc catgacattt aaccagaatt
     5161 ggtacatctc gtaaggagac gtcttatcgg catcaagcca gacggcatta ccttctgatt
     5221 taccgaattt tttcccggtt gagtcagtga tgagtggtac agtcatgacg tgcccagttt
     5281 tatcagcctt tttgcggagc aattcagtac cagctgtcat attgccccac tggtcagagc
     5341 cgccaatttg taaggttaca ttatgcttgt cattgagttc gtagaagtcg tagccctgca
     5401 tgatttggta agcaaactca gtgtaagaaa tgcctgtttc aatgcgtttt ttaacagagt
     5461 ctttactcat catgtagtta acggtgaagt atttaccgac atcacggagg aagtcaataa
     5521 agctgatttg cgagaaccag tcgtagttgt tgacaagctc tgctttatta tcaccatttt
     5581 caaaatcaag gaaagtagac aactgccctt taatcttgtc actccactcc aaaactgttt
     5641 ctttggtttg aaggctgcgc tctgcatctt taaaggaagg atcaccaatt aaacctgtgg
     5701 caccacccac aagagcgtaa ggtttgtgcc ctgctagttg caagcgacga gatgttaaga
     5761 tagccactag atggcccaga tgaaggctgt cagcggttgg atcataaccg gtataatagg
     5821 atacttgccc ttctgttaat gctttgacaa gggcttgttc atcagttgtt tgaaagacca
     5881 agccacgagc tttgagttct tcaaaaatat tcataggctt tctccatttt cattatagtt
     5941 tcgaatcatt atatcaaaaa acgctactgc tatgcaagct ttatcaaagt ttggtataat
     6001 gataaatgag gtattttatg gtgaaatgga acacgaaaca aaagcgtata agtcatcaaa
     6061 gattaggtct cttggatttg gggccggtgc tattacgtac gttgagacta ctgtctaact
     6121 ttttttatat tgttatcttc ctttttggaa tgatgggatt tggtatggca tttgggtatt
     6181 tggctagtca gattgaatct gttaaggtac caagtaaaga aagtttagtc aaacaagttg
     6241 aatcattaac gatgatttcg caaatgaact attctgataa tagtttaatt tctactttag
     6301 atacggattt acttcgaaca ccagtagcta atgatgcgat ttcagagaat atcaaaaaag
     6361 ctattgtatc aacagaagac gaacattttc aagaacataa aggtgtcgtg ccaaaagctg
     6421 tttttcgggc aacattggct tctgtattgg gatttggaga agctagtgga ggttcgacct
     6481 taacacagca attagtcaag caacaagttt tgggagacga tcccacattt aagcgcaagt
     6541 ctaaggagat cgtttacgct cttgccttag agcgttatat gtccaaagac aatatcttat
     6601 gtgattatct taatgtttca ccttttggcc gtaacaacaa gggtcaaaat attgctggtg
     6661 ttgaagaagc tgcgcgtggc atttttggcg tttctgccaa agatttaacg gtgccacagg
     6721 cagcattttt ggcgggtctt ccgcagagtc ctattgttta ctctccttat ttgtcaacgg
     6781 gacaactgaa gtcagaaaag gacatggctt atggcatcaa gcgtcagcaa aatgttctct
     6841 ataacatgta ccgtacaggt gttctgtcta aaaaagaata cgaggactat aaggcttatc
     6901 cgattcaaaa ggattttatt caaccgggaa gtgcaatagt aaataatcac gattaccttt
     6961 attacacggt gttagcggat gctaagaaag ccatgtatag ctatttgatt aagcgagata
     7021 aggtgtctag tcgtgacttg aaaaatgacg agactaaggc tgcttatgaa gagagagcct
     7081 taacagaatt gcaacagggt ggctatacca tcaccacaac cattaataag cctatttaca
     7141 atgcgatgca gacagcggca gctcagtttg gtggtttgtt agatgatggc actggtacag
     7201 ttcaaatggg aaatgtcttg acagacaatg cgactggtgc tgtgttaggt tttgttggtg
     7261 gtagagatta tgctctgaat caaaataatc atgctttcaa tacagttaga tcgccaggtt
     7321 ctagcattaa accgataatc gcttatggtc ctgctattga tcaaggttta atggggagtg
     7381 ctagcgtttt gtctaattac ccaacaactt actcgagtgg tcaaaaaatc atgcatgctg
     7441 atagtgaagg aacagccatg atgccacttc aagaggccct aaatacttct tggaacatcc
     7501 cagctttttg gacacagaaa ttactgcgtg aaaaaggggt cgatgtcgaa aattatatga
     7561 caaaaatggg ttataagatt gcagactact cgattgaaag tttacctcta gggggcggta
     7621 ttgaagtctc ggttgctcaa caaaccaatg cttaccaaat gctttcaaac aatggcttat
     7681 atcaaaagca atatattgta gataagatta ctgctagcga tggtacagtc gtttacaaac
     7741 atgaaaataa gccaattcgt attttttctg cagcaacagc tacgatttta caagaattgt
     7801 tgagaggtcc gattacttca ggcgctacga ctactttcaa gaaccgtttg gcggctatta
     7861 atccgtggct tgctaatgct gattggattg gtaagaccgg aacaactgag aattatacgg
     7921 atgtttggct agtcctgtct actccaaaag ttaccttagg cggttgggca ggacatgatg
     7981 acaatacctc attagcgcca ttaacaggat ataacaataa ttctaattac cttgcctatt
     8041 tagctaatgc cattaatcag gccgatccca atgttattgg agtagggcaa cgcttcaact
     8101 tagatccagg agtcattaag gcgaatgtct tgaagtcaac aggtttacaa ccaggaactg
     8161 ttaatgtcaa tggacatact ttttctgttg gtggagaaat gaccaccagt ctatggtccc
     8221 aaaaaggacc gggggctatg acttaccgat ttgctattgg tggcacggat gccgattatc
     8281 aaaaagcctg ggggaacttt gggttcagaa aaaattaggt tgccatttat cgataaaaag
     8341 ggtataatag caataactat ttgtcgtcca atctagctga aatattgtcc agttaggaag
     8401 aacagcagtt aaatcacact gataaagtca gatttagctg ctctttttgt gtctattttt
     8461 agaaaagata gggtttgtaa cctatattta aatattctaa aaattaacat ttagggcaaa
     8521 tgataactta gttgcgattt gctgaaacag caaagcttaa atagaagaag gagctaaaaa
     8581 cttggcagga catgaagttc gatacggaaa acaccgtaca cgtcgtagct tttcaagaat
     8641 caaagaagtt cttgatttac caaatttgat tgaaattcaa actgactcat tccaagattt
     8701 cctcgattca ggtttgaaag aagtatttga agatgtactt cctatttcaa actttacgga
     8761 tactatggaa cttgaatttg ttggttacga atttaaagaa cctaaatata cccttgaaga
     8821 agctcgtatc cacgatgcaa gttattctgc accaatcttt gttaccttcc gtttggtcaa
     8881 taaagaaact ggtgagatta aaactcaaga agtcttcttt ggtgatttcc caatcatgac
     8941 ggaaatgggt acctttatta tcaatggtgg tgaacgtatc atcgtttctc agttggtgcg
     9001 ttctccaggt gtttatttca acgataaagt tgataaaaac ggtaaagttg gttacggatc
     9061 aacagtgatt cctaaccgtg gggcttggtt ggaattagag actgactcaa aagacattgc
     9121 ctacactcgt attgaccgta cccgtaagat tccattcaca accttggttc gtgcccttgg
     9181 tttctcaggt gatgatgaaa ttgttgatat ctttggtgaa agcgaccttg ttcgtaatac
     9241 cattgaaaaa gacattcaca aaaatccaag tgattctcgt acagacgaag cccttaaaga
     9301 aatttacgag cgtcttcgtc caggtgagcc aaaaactgca gatagctctc gtagtctctt
     9361 gattgcgcgt ttctttgatg cacgtcgtta cgatttggct gcggttggtc gttacaaagt
     9421 gaacaaaaaa cttaatatca agactcgtct tttgaaccaa atcattgctg aaaaccttgt
     9481 ggatgctgaa actggcgaaa ttttggtaga agctggaact gagatgactc gtagcgtcat
     9541 cgaatccatc gaagaacacc ttgacggtga tttgaacaag tttgtttaca caccaaatga
     9601 ttacgctgtg gttactgaac ctgttgttct tcaaaagttc aaggttgtgt caccaattga
     9661 tcctgatcgt gtagtaacta ttgttggtaa tgccaatcca gatgataagg ttcgtgcatt
     9721 gacacctgct gacattttgg cagaaatgtc ttacttcttg aaccttgctg aaggtcttgg
     9781 aaaagttgac gatattgacc acttgggtaa ccgtcgtatc cgtgccgttg gtgaattgct
     9841 tgccaaccaa ttccgcatcg gtcttgctcg tatggagcgt aacgttcgtg agcgtatgtc
     9901 tgttcaagac aacgatgtgt taacaccaca acaaatcatc aatatccgtc ctgtcacagc
     9961 agctgtcaaa gaattcttcg gttcgtctca gttgtcacag ttcatggacc aacacaaccc
    10021 attgtcagag ttgtctcaca aacgtcgttt atctgcctta ggacctggtg gtttgacacg
    10081 tgaccgtgct ggttatgagg ttcgtgacgt gcattacacg cactatggcc gtatgtgtcc
    10141 gattgaaaca cctgaaggac caaacattgg attgattaac aacttgtctt catttggaca
    10201 tcttaataaa tatggtttca tccaaacacc ttaccgtaag gttgaccgtg cgactggtag
    10261 ggtaactaac gaaattgttt ggttgactgc cgacgaagaa gacgaataca cagttgcaca
    10321 ggccaattcg aaactaaacg aagatggcac ttttgctgaa gaaatcgtta tgggtcgtca
    10381 ccaaggtaat aaccaagaat tttctgcaag tgttgttgat ttcgttgacg tttcccctaa
    10441 acaggtagtt gctgttgcga cggcatgtat tcctttcttg gaaaacgatg actccaaccg
    10501 tgccctcatg ggtgccaaca tgcaacgtca ggctgtgcca ttgattgatc caaaagcacc
    10561 atatgttggt actggtatgg aatatcaagc tgcccatgac tcaggcgctg cggtgattgc
    10621 tcagcacaat ggtaaagttg tcttttctga tgctgaaaaa gtggaaatcc gtcgtcaaga
    10681 tggctcactt gatgtttacc acattaccaa attccgtcgt tcaaactcag gaacagccta
    10741 taaccaacgc acccttgtta aagtaggaga catcgttgaa aaaggtgact tcatcgctga
    10801 tggaccatct atggaaaacg gtgaaatggc tcttggacaa aacccagtcg ttgcttacat
    10861 gacttgggaa ggttacaact tcgaggacgc tgttatcatg tctgaacgcc ttgtgaaaga
    10921 ggatgtttac acatctgttc acttggaaga attcgaatct gaaacgcgtg atacaaaact
    10981 tggccctgaa gaaatcactc gggaaatccc aaatgttggt gaagaagccc tcaaagacct
    11041 tgacgaaatg ggcattatcc gtatcggtgc tgaggtgaaa gaaggcgaca tcttagtagg
    11101 taaagtcaca cctaaaggtg aaaaagacct ttctgctgaa gaacgtttac ttcacgccat
    11161 ctttggggat aaatcgcgtg aagtgcgtga tacctcactt cgtgtccctc acggtggtga
    11221 tggtatcgtt cgtgatgtga aaatctttac acgcgctaac ggcgatgaat tgcaatcagg
    11281 tgttaatatg cttgtgcgtg tttacatcgc tcaaaaacgt aaaatcaagg tcggagataa
    11341 aatggccggt cgtcacggaa acaagggtgt cgtttcacgt attgtaccag ttgaagacat
    11401 gccatacctt ccagacggaa caccagttga catcatgttg aaccctcttg gggtgccatc
    11461 acggatgaat attggtcagg ttatggaact tcaccttggt atggctgctc gtaatcttgg
    11521 cattcacatt gcaacacctg tctttgacgg ggcttcatca gaagaccttt gggacactgt
    11581 tcgcgaagct ggtatggata gcgatgctaa gacggtcctt tatgatggtc gcaccggtga
    11641 accatttgac aaccgtgtat ccgttggtgt catgtatatg atcaaacttc accacatggt
    11701 tgatgataaa cttcatgccc gttctgtagg accatactca cttgttaccc aacagccact
    11761 tggtggtaaa gctcaatttg gtggacaacg ttttggtgag atggaggttt gggcccttga
    11821 agcttatggt gcatcaaatg ttcttcaaga aatcttgacc tacaagtcag atgacgtcac
    11881 aggacgtttg aaagcctatg aagcgattac taaaggtaaa ccaattccaa aaccaggtgt
    11941 accagaatcc ttccgtgttc ttgtaaaaga attgcaatcg cttggtcttg atatgcgtgt
    12001 gcttgatgag gatgataatg aagtggaact tcgtgatctt gatgaaggtg aagacgatga
    12061 cattatgcat gttgacgatc tcgagaaggc acgtgaaaaa caagctcaag aaacccaaga
    12121 agtttctgaa acaactgacg aaaaataagc aatcaattct tattaaataa ttatttactg
    12181 gtctggggca aaggtcccag gaactggtaa agtcatcaaa ggcagaaagg taaaactagt
    12241 ggttgacgta aatcgtttta aaagtatgca aatcacatta gcctcaccaa gtaaggtccg
    12301 ttcatggtct tatggtgaag ttaaaaaacc tgaaacaatc aactaccgta cattaaaacc
    12361 agaacgtgaa ggactctttg acgaagtcat ctttggtcca acaaaagact gggaatgtgc
    12421 gtgtggtaag tacaaacgta tccgttataa agggatcgtt tgtgaccgct gtggggttga
    12481 ggtaactcgt gctaaagtac gtcgtgaacg tatgggtcac attgagttaa aagctcctgt
    12541 atcacatatc tggtatttca aagggattcc atctcgtatg ggattgactc ttgatatgag
    12601 tcctcgtgcc cttgaagaag tgatctattt tgcggcttat gtggtcattg atccaaaaga
    12661 tacaccgctt gaaccaaaat cattattaac agaacgtgaa taccgtgaaa aactacaaga
    12721 gtatggtcat gggtcatttg tcgctaagat gggtgctgaa gccattcaag atctcttgaa
    12781 acgtgtggac ttggcagctg aaatcgctga attaaaagaa gagttgaaat ctgcttctgg
    12841 tcaaaaacgg attaaagcag ttcgtcgttt agacgtcctt gatgccttta acaaatctgg
    12901 aaataaacca gaatggatgg ttcttaacat cctgccggtt attccaccag atcttcgtcc
    12961 gatggttcaa ttggatggtg gccgttttgc ggcatcagac ttgaatgact tgtaccgtcg
    13021 tgtgattaac cgtaacaacc gtttggcacg tttgttagaa cttaatgccc ctggcatcat
    13081 tgttcaaaat gaaaaacgaa tgcttcaaga agccgttgat gctttgattg ataatggtcg
    13141 tcgtggtcgt ccaatcactg gaccaggaag tcgtccattg aaatcattga gccacatgct
    13201 taaaggtaaa caagggcgtt tccgtcaaaa cttacttggt aaacgagtag acttctctgg
    13261 acgttccgtt atcgctgttg gtccaaccct taaaatgtat caatgtggtg tcccacgtga
    13321 aatggctatc gagcttttta aaccatttgt aatgcgcgaa attgttgcca aagaatatgc
    13381 tggtaacgtt aaagccgcta aacgtatggt tgaacgtggc gacgaacgca tctgggatat
    13441 cttagaagaa gttatcaaag aacacccagt cctacttaac cgcgcaccga cccttcacag
    13501 acttggtatt caggcttttg aaccggttct tattgacggt aaggcacttc gtcttcaccc
    13561 acttgtgtgt gaggcctaca atgccgactt cgatggagac caaatggcca tccacgtgcc
    13621 actttcagaa gaagcacaag ctgaagctcg tcttttgatg cttgctgcag agcacatctt
    13681 gaaccctaaa gatggtaaac cagttgttac cccatctcag gatatggttc ttggtaacta
    13741 ctatcttacg atggaagatg ctggtcgcga aggcgaaggt atgattttca aggataaaga
    13801 cgaagctgtg atggcatatc gtaatggcta tgctcatctt catagtcgtg tgggtatcgc
    13861 tgttgacagc atgccaaaca aaccttggaa agacagtcaa agacataaaa tcatggtgac
    13921 aactgttggt aagattctct ttaatgacat catgccagag gaccttcctt acctccaaga
    13981 gccaaacaat gccaacttga cagaaggaac acctgataaa tacttccttg aacctggtca
    14041 agatatccaa gaagtgattg acggcttaga aatcaatgtg ccattcaaga agaaaaacct
    14101 cggtaacatc attgcggaaa ccttcaaacg tttccgtaca acagaaacat cagccttcct
    14161 tgaccgtttg aaagaccttg gttactacca ttcaaccctt gctggtttga cagtgggtat
    14221 cgctgacatt cctgttattg ataataaagc tgaaatcatt gatgctgctc accatcgtgt
    14281 tgaagaaatt aacaaagcct tccgtcgtgg tttgatgaca gatgatgacc gttatgttgc
    14341 cgttacaaca acatggcgtg aagctaaaga agcccttgaa aaacgtctga ttgaaacaca
    14401 agatcctaag aacccaatcg ttatgatgat ggactcagga gctcgtggta acatctctaa
    14461 cttctcacag cttgcgggta tgcgtggttt gatggctgct cctaacggac gcatcatgga
    14521 acttcctatc ttgtcaaact tccgtgaagg tttgagcgtt ttggaaatgt tcttctcaac
    14581 ccacggtgca cgtaaaggga tgaccgatac ggcccttaaa acagccgact caggttatct
    14641 tactcgtcgt ttggttgacg ttgcccaaga tgttatcatt cgtgaggacg attgtggcac
    14701 tgatcgtggt cttcttatcc gtgctattac agatggtaaa gaagttaccg aaacgcttga
    14761 agagcgtctt caaggtcgtt acacacgtaa atcagtcaaa caccctgaaa ctggtgaagt
    14821 cttgattggt gctgaccaat taatcactga agacatggct cgtaagattg ttgatgcagg
    14881 tgttgaagaa gtgaccattc gttctgtctt tacctgtgcg actcgtcatg gtgtctgccg
    14941 tcactgttat ggtatcaact tggcaactgg tgatgctgtt gaagtgggtg aagcagttgg
    15001 tactattgct gcccaatcta tcggtgagcc tggtactcag cttaccatgc gtaccttcca
    15061 cacgggtggt gtagcctcaa ataccgatat cacccagggt cttcctcgta ttcaagagat
    15121 ctttgaagca cgtaatccta aaggggaagc ggtcattact gaagtgaaag ggaatgtcgt
    15181 cgagattgaa gaagatgcgt caactcgtac caagaaagtc tacgttcaag gaaaaactgg
    15241 catgggcgaa tatgtcgtac catttacagc acgtatgaaa gttgaagttg gcgacgaagt
    15301 taatcgcgga gctgccctta cagaagggtc aattcaaccg aaacgtctcc ttgaagtgcg
    15361 tgataccttg tcagttgaaa cgtaccttct tgcagaagta caaaaagttt accgtagcca
    15421 aggggtagaa atcggagaca aacacgttga ggtaatggtt cgccaaatgc ttcgtaaagt
    15481 tcgtgtcatg gatccaggtg atacagacct ccttccaggt acacttatgg atatttctga
    15541 tttcacagat gctaacaaag atattgttat atctggtggt attcctgcga catctcgtcc
    15601 agttcttatg ggtattacta aggcttccct tgaaaccaat tccttcttat cagctgcatc
    15661 cttccaagaa acaactcgtg ttcttacaga tgctgctatc cgtggtaaga aagaccactt
    15721 acttggtctt aaagaaaatg ttatcattgg taaaatcatc ccagctggta ctggtatggc
    15781 gcgctaccgt aacattgaac cacaagcgat gaatgagatt gaagtgattg atcatacaga
    15841 agtctcagca gaagcagaat aatctcatga aagagtcctt aggggctctt ttttgtctga
    15901 gtttgttggc agtaaaaagc attgacaatc agtcttagtc ccaatgagca gatgtttttc
    15961 aaaatactta tgatttagct ataataatgc ataagaggaa tgggtaatgt gttatgtatc
    16021 aagtaattaa aatgtatggt gattgggagc cttggtggtt catcgatgga tggcaagacg
    16081 atattataga tgagcaacaa tttagtgact ggcaagaagc gcttgattat tttaatcaag
    16141 aatggcagcg catgaaagct atttttccta gttatcatag ccaaaagaat ttgttagcta
    16201 ctttttggga aaaagaagat aaaagatggt gcgaggactg tgacgaagat ttgcagcagt
    16261 ttcattctct tttactcctt aaaaataaag atattgtacc aagcaataat tatattcctg
    16321 aatttgaaca acgaaatgat tcaccacagg tagcttatct ttgcaagtta aacctttaag
    16381 tgtttgttaa aaacaaaata agttaaaaga aaatatcact tcttatgata ttttcttttt
    16441 ttgtttacga ataaatgagt aaggaggaat tatggtacaa gcattagcaa aagctattct
    16501 agcaaaagct gaacaggttc aggcacaaga tatttatatt ttgccaagag cagatcaata
    16561 tgatcttttt ttacgaatag gagatgaaag gagattagtt gatgtttatc agagcgatcg
    16621 gatggctcct cttattagtc actttaaatt cgttgcagga atgatagttg gtgaaaagag
    16681 acgttgtcag gtgggttcat gtgattataa gcttagtaaa gataagcagt tatctttgcg
    16741 cttatctagc gtgggtgatt atcgcgggca agaaagctta gtgattcgtc tgcttcatca
    16801 tcaaaataaa agtgtacatt attggtttga tggattgaca aaagtagcca atcaagttgg
    16861 cggtagaggg ttgtatttat ttgcaggacc agttgggtct gggaagacaa ccttgatgta
    16921 ccagctgatt tcgaattatc atcaagaagc acaggttatt agtatagaag atcctgtaga
    16981 aattaaaaat caccagattt tacaattaca agtgaatgat gatattggta tgacttatga
    17041 caatttgatc aaactgtctt tacgccatcg accagatatt ttagttattg gtgagattcg
    17101 agatagtcaa acagcaagag ccgttattag ggctagtcta acaggtgcca tggttttttc
    17161 aacggttcac gctaaaagta tctcgggtgt ttatgtaaga ttgttagaac ttggtgtaac
    17221 gaaagcagaa ctgtctaatt gcttagcatt aattgcttac caaaggttac ttaatggagg
    17281 agcattgatt gactctactc aaaacgaatt tgaatattat tcctcatcga actggaatca
    17341 acaaattgat cagcttcttg aggcaggaca tctcaatccc aagcaagcta agcttgaaaa
    17401 aattatctag taaacatcag cataaattca ttcaattact agctaatctt ttatctacag
    17461 gatttagctt cgcagaggtt attgcttttt taaaaagaag ccagttgctt cagctagatt
    17521 atgttcttaa aatggaagag tctttattaa aaggacaagg cttagcagat atgttgtcgg
    17581 gtttaggttt ttcagatgct attcttactc aaattagttt agctgataga cacggtaata
    17641 ttgaaacaac attagtagcg attcaacatt acttgaacca aatggcaagg atcagacgaa
    17701 aaactgttga agttatcacc tatcctctta ttcttttact ttttcttttt gtgatgatgc
    17761 tagggttgag acgctattta atccctcaat tagaaactca aaatcagata acttactttc
    17821 ttaaccattt tcctgccttc tttataggtt tttgctcagg tcttattttg ttgttcggga
    17881 tggtatggct acgatggcga tctcaaagcc gcttgaaact ttatagtcgg ctaagccgtt
    17941 atcctttttt aggtaaactg ttaaaacaat acttaactag ttattatgct agagaatggg
    18001 gtacgttaat aggtcaaggt cttgatttga tgactatttt agacattatg gctattgaga
    18061 aatcctcact aatgaaagaa ttagctgagg acatcagaat gagtctgctt gaagggcaag
    18121 cctttcacat taaagtagct acctaccctt tttttaaaaa agaattaagt ttaatgattg
    18181 aatacggtga aatcaaatcg aaactggggg gctgagttgg aaatctatgc ccaggaaagc
    18241 tgggaacaat tttttagtca gctttatcaa gtgacacaac ttattcaacc agctattttt
    18301 ttagtagttg ctgtgacaat cgtcatgatt tatgcggcaa tcctattacc aatttaccaa
    18361 aatatgggag gtatttttta agatgattaa tcaatggaac aacttacgac acaagaagct
    18421 aaaaggattt actcttctag aaatgttatt ggtgattctt gtcatcagtg ttttgatgct
    18481 attatttgtg cctaatttaa gcaagcaaaa agacagggtt acagaaacag gtaatgccgc
    18541 tgttgttaaa ttagtggaga atcaagcaga actatatgaa ttatctcaag gctcaaaacc
    18601 aagtttgagc cagttaaagg cagatggtag tatcactgag aaacaagaaa aagcttatca
    18661 agactattat gacaaacata aaaatgaaaa agcccgtctt agcaattaaa gcttttactt
    18721 tgcttgaaac tttactaagt ttgtcagtga tgagtttcat tatattggga ttgtctgtac
    18781 cagtgacaaa aagctatcaa aaagtagaag agcatctgtt ttttagccat tttgaacatt
    18841 tgtatcgaca tcagcaaaag ttagccatat tacagcaaaa acagcgcgtc ttggatattt
    18901 cttcaacaaa aattgttaca gaaggtaata gcctaacagt tcctaaatca ataacagtga
    18961 atcatcctta tcggttagtt attgatcaga tgggaggcaa ccattcctta gctaaaatta
    19021 tttttgacat gactgatcga cgctttaaat accaatttta tctagggagt gggaattatc
    19081 aaaaaacaag tcaaagctta catagccctt gaaagtatga tcgcaacagg catcctcttt
    19141 agtattgtca ttctcgtctt gagcagttta cagcagagtc aggctgctct aacgtactat
    19201 cgaaagcagc aagaaaagct taatctagct ttgatggcag tacaaactag aactaaagag
    19261 atgacattga atggttgtca tattactatt ttacgtacgg atagatatat tagtattcac
    19321 gatgacgaag gagaagtgat gaagattgag taaacaatta agtaacataa aagcttttac
    19381 ccttctagag gcgttaatag ccttactcgt gatatcaggg tctttattgg tttatcaagg
    19441 tttgacccag accctcctta aacgtagcca ttatctagcc cgtcatgatc aagacaattg
    19501 gctcttattt tctcatcaat tgcgagagga gttaagtgga gcaagatttt acaaagtagc
    19561 tgataataaa ctatacgttg aaaagggaaa gaaagtacta gcttttggcc aatttaaaag
    19621 tcatgatttc cgaaaatcag ctagtaatgg aaaagggtat caacccatgt tatttggaat
    19681 atcacgtagt catattcaca tagggcagtc acagatttgc attactttaa agtggaaaag
    19741 tgggttagaa aggacttttt attatgcctt tcaagactaa tctcaaagca ggcatccttt
    19801 tgtatgctat gtttatggct agtatttttt tgctggtttt acaggtttac ctttctcaag
    19861 tgacagctct acacaaggaa taccaagctc aaactgacta tgttaaagcc cgactgatag
    19921 cagaaatagt ttatcaagat catagatata aagcttctaa tcctgtcttt tttaaaggtg
    19981 gtcaagtcat ttgtcgagag cgaaaagaga gatggatgtt aattgttaag ttagatcagc
    20041 aacgacagta tcagtttgaa taccttaaac ccaaacaata tagtcaataa atagtattgt
    20101 tgtcgtaaat ccttaaaatg atccaatata tagtaattaa aggtgacact tcttttcatt
    20161 tcaagtgtaa tttggtatga taaggttatg acttttgaaa aaattgaaga agcttatcag
    20221 ctgctcttag agaactgtca actaattgaa aatgatctaa aaacacatat atacgatgcc
    20281 attgttgaac aaaactcctt ttatttaggg gctgagggag ctagtcctca agttgctcaa
    20341 aatagtgata aactgaaagc cttgtgcctg acaaaagaag aatggcgtaa ggcctaccag
    20401 tttcttttta ttaaggcagc tcagactgag caactccaag ccaaccatca gttcacacca
    20461 gatgctattg gcttcattct gctgtatctt ttggaacaat tgagtgataa agatagctta
    20521 gaggtacttg agattggaag tggaacaggg aacctagccc aaacccttct caacaacacg
    20581 agcaagagcc ttgattatgt agggattgaa cttgatgatc tcttgattga tctgtcagcc
    20641 agtattgctg agataatgga ttcttcagct cattttattc aagaagatgc ggtaaggcct
    20701 caattactaa aagaaagtga cattgtcatc agtgacttac cagttggtta ttatcctaac
    20761 gatgatattg ccaaacggta caaggtggct agttcagata agcataccta tgcccatcat
    20821 ttattaatgg aacagtcttt aaaatacttg aaaaaagacg gttttgcgat ttttctggca
    20881 ccagtcaatt tattgacgag ccctcagagc cagttattga aacagtggtt aaaagattat
    20941 gctcaggtgg tggccttgat tacgctacca gattctattt ttggtcatcc ctcaaatgcc
    21001 aagtccatta ttgtcttaca aaaacaaaca gaccacccaa tggaaacctt tgtctatcca
    21061 attcgggatt tgaagcttgc agagaatatt catgatttta tggaaaattt caaaaaatgg
    21121 aaactgagta atgtcaatta attgattttt tgttataata aaaaagcatc acagaaaacg
    21181 atttcaagag aggttaaaaa tgtcaaagac aattgcaatt aatgcaggta gttctagttt
    21241 aaaatggcaa ctttatcaga tgccagaaga agaagtgtta gcacaaggaa ttattgagcg
    21301 tatcggtctc aaggattcta tttcaacagt taagtacgat ggcaaaaaag aagagcaaat
    21361 tcttgatatt cacgatcata cagaagctgt taaaatctta ttgaacgatt tgattcactt
    21421 tggaatcatt gcagcttatg atgaaattac aggagttgga caccgtgttg ttgctggtgg
    21481 tgaacttttc aaagaatccg ttgtggttaa tgataaagtt cttgaacaga ttgaagaatt
    21541 atccgtttta gctccacttc acaatcctgg agcggcggca gggattcgtg ccttccgtga
    21601 tattttgcca gatattacca gtgtttgtgt gtttgacacg tcatttcaca ctagcatggc
    21661 aaagcatact tacctttacc caattcctca aaaatattat acggactaca aggttcgtaa
    21721 atatggggcg catgggacaa gtcataaata tgtagcgcaa gaagctgcta aaatgcttgg
    21781 tcgtccatta gaagaattaa aactaattac tgctcatatt ggaaatggtg tctcaattac
    21841 agctaattac cacggtaaat cagttgatac ctcaatggga ttcactccat tagctggtcc
    21901 tatgatggga acacgttctg gtgacattga cccagctatc attccttatt taattgagca
    21961 agacccagaa ttaaaagacg ctgctgacgt tgtgaatatg ttaaacaaaa aatcaggtct
    22021 tagtggggtg tcaggcattt ctagtgatat gcgtgatatc gaggctggtt tacaagaaga
    22081 taatccagat gctgttttag cttacaatat ctttattgat cgcattaaaa aatgcattgg
    22141 tcaatatttc gctgttttga atggagcaga tgctttggtc tttacagctg gtatgggtga
    22201 aaatgcacca ttgatgcgtc aagatgttat tggtggctta acatggttcg gaatggacat
    22261 tgatcctgag aaaaatgttt ttggataccg tggtgaaatt tcaactcctg agtcaaaagt
    22321 gaaggttctt gttatctcaa cagacgaaga attgtgcatc gcgcgtgacg ttgagcgttt
    22381 gaaaaataca aaataaaaga gactaagtct caatagatta accaagtaag gcaacacttt
    22441 acttggtttt ttatgaggtt tatctgttag ttatggtgcc taggtattag ttctgatcag
    22501 tctccttgct ttttgtaatc ttgtgctagg cgatttggat gtcagcctta tttagaagtt
    22561 tttaattgct tcaacgcttt tcttgtatgt gtttatagag cccaatgatc taaaagacta
    22621 tttgataacg gtttatgatg agcgtaatcg tgcgattcga aaacagacac aagtttactg
    22681 cttttacctg atgattgttc tatttgttgc cttgttcttt ttcttccctt gcttaaccat
    22741 tcgagacctt gtttcttata agctagcttt gatttttgct tacctttact tgattatcag
    22801 aagtctggtg gctaagaaaa tggaggcact agggaaaata acaactaata gtcaaaagcc
    22861 tccgtttgat acgagtcagg ttctttgcta gatgacttgt ctaacggttg agtttcctgt
    22921 ctggtcaacg gaggtgtttg tattgttgtc tgatttgtat tggggcactt attttacaag
    22981 cttttagcct tatcgatggt tttgtcaatg gcagagctga cagtagttgt gaggccaagg
    23041 cgttctaact ccatcagacc agcaatagtt gtgccaccgg ggctacaaat agcgtcaatg
    23101 aaatcgtgcg gactttgaga actggtcttg agattgctgg cactagccaa gactgtttga
    23161 gtaacaatct ccagcgcctt tgctttaggc atgccattct tgacgccagc cttagccaaa
    23221 gcctcaataa agagataaat ataggcagga cttgaccctg ctaaagcggt aaaggtgtca
    23281 aaatcctttt cactaatatc aaatgtgcta ccaaagctat ctgttaagtc tcgaacacgt
    23341 gcttgtaatt cctgggacac caaagcattt cccgttaaag cggtactgct ttggagaatt
    23401 tgtgcattca tgtttggcat gatacgcagc agcggaaggt cttgtcctac gaatgttgct
    23461 agtcgttgaa gggaaatgcc tgctgccata gatataatag gctgtttgaa gtgaagcggt
    23521 ttgagtaccg tttcaaatag ttgaggcttg atgcctaaaa taacaagatc aacctggtca
    23581 ataaggtctt ggtgggacat agcataaggc agtgctaact gctccgcaat ttccttggac
    23641 cgttctaaag atgatcctga aatgataagt tcatggggtg tttgtttaag gcctttgatg
    23701 atagcgctag ccattttgcc aataccaata atgccaattt tcattctgtt gctccttgtg
    23761 ggatattatg gttaatcagg ctaatgctag tttagtaaca tttaatcaag tcaacggttg
    23821 agcgatccag ttttttgata atggcttgta agaaggcttg ggcttctacg aaatcatcca
    23881 tagcgtagag ggtttgatga gagtgaatgt agcgtgcaca gactccgatg gttgttgatg
    23941 ggacaccacc attttgaagg tgtgcagcac ctgcatctgt gcctcccttg ccacaatagt
    24001 attggaaatt gacaccagct tcctcagcag tagtcagtaa gaagtcgcgc atatctttga
    24061 gcatgacatg gcctgggtcg tagaaacgca acaaggtgcc atctccgatt gttccaggat
    24121 tgccataaat atcaccagca ggcgaacaat ctactgcgaa aaagagttca gggtcgaact
    24181 tggtggttga gacgtgggct ccgcgcagac caacttcttc ttgaacgtta gcacctgcaa
    24241 ttagggtgtt gttaaggtct tgtcctttta acgcttcaag catttctgtt atcatgagaa
    24301 caccatagcg attgtcccaa gcttttgaaa taatattttt ttgattggct gttaggatcg
    24361 tttcagattg agggacaata atatcacccg gtgtaatacc aaatctttca gcttctgcct
    24421 tatccgtaaa gccaccatca aacacaatat cttcgatatg tggtagacta gcagagccat
    24481 ttgccccacg gagaaaatga ggaggtaccg atcctgaaat aaggggaata acttggccag
    24541 tgcgtgtgta aagggtaaac cgttgtgaac tgacaacaag tgggttccaa ccaccgatac
    24601 caaccacgcg tagcgttccg tcaactttga tatcactgac cataaaaccg acttcgtcca
    24661 tgtgcgcagc tactaaaata cggggggctt tttcagcttt actatctctg ataccaaaaa
    24721 tgccaccaag cccgtctgtt tcaacacggt caaccagcgg ggttattttg gtgcgtaggt
    24781 agtcacgaac gctatgttca tagcccgcaa tgccatccag ttcggtaact tctttgattt
    24841 ttgagaataa gtctgtcatt tttcatctcc atttacaagg tttcagacca gttcaacgcg
    24901 gtcatctccc tatattctac cactttttaa gtaagaatgg gtttcacagc aaagaaaaat
    24961 cccagagact agagatctct ggaagaagtg tttgtctttt ggcgataacc tgttttttta
    25021 ggcagcaagg aaatcattaa aatgataaag cacaagctgg ttaataagaa tagtagggcg
    25081 cttaggatgc gaaaagactc ttcactagcg aaaagtaagg ataatggagt cataaggaga
    25141 accttccatt ttaggttaat cagtgatttt tatagtgtgg ttaaattaat aataaacaac
    25201 acctaatcaa tgtattttta gtttagttgt ttttactatt tttgtcaata cataacagta
    25261 gaaatcttta gttttcttat ttcagatcgt ccaatttgat ctttttatga taaaatgagg
    25321 gatatgagta aaaagaaaat aggtatgatt tcaggtatct ttggatttag tttagctatt
    25381 ggcctaggaa tagttatcaa agattattgc caagacaggc agcgtcgaca aatgacaagg
    25441 gatttacgca cctttttttc acctttagga caaatcgaag ttttatatat caatccttgt
    25501 caggtcaaac aagattatat ttcaggtggg gttgttatgt caaacggcaa acagtaccaa
    25561 ttcacctatc acagtcgaca aattagtttt gaggaggaca agggatgatc agaccgactt
    25621 cttatgagtc attagcggct cttattgaaa aagaagataa gctggtgtta ttttttacgg
    25681 cagactggtg tccagactgt caatttattt atcccattat gccagaaatt gaagcagaac
    25741 ttacagatat gacttttgtt tgtgttaatc gtgatcagtt tatagaggta gcacaaaagt
    25801 gggatatttt tggtattcct agttttgtcg tgattgaaaa aggtcaggaa gtagggcgtc
    25861 tggttaacaa aatgagaaag acaaaaactg agattatgca ttttttagct gcttatcaat
    25921 aagaaaagag gaagaataaa tgatttttgc atacaataaa gaacaagttg gcgatgtctt
    25981 gatggttatc ttacaagaca ccaaagatat caaacgtcaa gtagaacgaa aaggcaaagt
    26041 agcccgtgtt tttgcagaag aaagcggcaa aacccttgct tggaatatct ttgaagcgtc
    26101 aagcttgatt actattgaag gcaatggaca gatttttttg acagacgagg accttgcaag
    26161 attaaatgca gagcttgcta aggaaggatt ttcagaaagg cttgaaccga ctgtgggacc
    26221 tgtttttgtg gttggtcaaa ttgttgagat ggtggctcat ccagatagcg accatcttaa
    26281 tatctgtcaa gtggctattg gtgaagatca aacggttcaa atcgtagcgg gcgcaccaaa
    26341 tgctgcgctt ggtttaaaaa cgattgttgc cttaccaggt gctataatgc caaatggtag
    26401 tctgattttc ccaggaaaat tgcgtggtga agaaagttat ggtatgatgt gctctcctcg
    26461 tgagttagcc ttgccaaatg caccgcaaaa acgtggcatt attgaacttg atgagtcagc
    26521 tgtggtagga gaagcttttg acctagccaa acattggaaa ggttagaaaa accagctgaa
    26581 ataagactgt atttaactaa atgaccagaa aaaaaggatt aggagcccct agtccttttt
    26641 tcttatgttt tcaaaaacgt ttaaaatgaa acttatttta ccacaatttt tacgaataat
    26701 aagataagga ggtcagtatg tataataaag tgatagcaat cggtcgtttg gtggctaaac
    26761 cagaattggt aaaaaccgct acggataagc atgtagcacg tctctcttta gctgttaatc
    26821 gaagatttaa aaatgcttct ggagagcgag aagcggattt tatctctgtt gttgtttggg
    26881 gaaagttagc agaaactctg gtttcttatg ctagcaaagg tagtttgatg tctattgatg
    26941 gcgaacttag gacccgcaag tatgataaag atgggcaagt gcattatgtg acagaagttc
    27001 tctgccaatc atttcaactg cttgaaagtc gtgctcaacg cgctatgaga gaaaataatg
    27061 ttactaatga tctagttgat ttagtcttag aagaagatac tcttcccttt tgatagggga
    27121 taatgcttct catcacggtt cagctgatta ctgaaatata tgatgaggtg atatccgagc
    27181 aacaaaagtg tgaccagata cttctgataa aaataaaaaa acaccttacg agtatgaaca
    27241 aagtttcaag tgctagatgt tggaactttg ttcatcatag gaatagtagg gtgtttttta
    27301 gtgtattact tctttttgtt gctagtgtta aggtttactt gcttacaaac ggttatcagg
    27361 ccactagaac tcttataata aatggagctc tttgagtttg gtgtcaatca tttttaagac
    27421 agtcgccaaa tcttgtgggt tttgaacgaa atcaagggaa ttgccatcaa ttttcatttt
    27481 tggagagacc ttgtagtctt cgtaccaggc tgggtattca ccgtggactt gatggtaata
    27541 ttgctcaaga ctaggattgc cgtcgacctg ctcaaaactt cggccacgtt tttcaatgcg
    27601 ctcaagcatt ttgtcaaaag acacatcaat gtagatgaga agatcagggc gttttttagg
    27661 catgccttct agttcttcta acatgttggc gagaagttcc tgatagatgt caagttctgt
    27721 cttagtgaca ttgccatttt tgtagttaag ttttaaaaag agttcgtctt caaaaataga
    27781 gcggtcaaga atgttgttat cggcttgata agcttctttg atggacttaa accgtttatt
    27841 caaaaaataa atttgaagta aaaaggcgta ctttttaggg tcttggtagt agaggtctag
    27901 cacggggtta ttatcaacag cttcgtaaaa aacgtcagtt cctaaatgct ctccaagtgc
    27961 agcagcaagc gagctcttgc cagccccaat tgttccagct agtacaatca acatgcgtct
    28021 ccttctaatg tcattagcgt actgtttcga agatggcttc aacctcagct agagtctcag
    28081 cgcgtgaaac agcaccacga actttggcag cacctgctgt tccgcgaaga tagtgtggcg
    28141 ctaagccccg aaattcccga acagcaatgg tttcaccttt gaggttaatc aggcgtttga
    28201 ggtggtcttt ggcgatgtct aattttttgg caaaaggaag atcagccaat tcttgaccag
    28261 tttcaaagaa atgattgatt tgggtaaaaa gataaggatt gttcatggct gcgcggccaa
    28321 tcatcacggc atctacaccg atttcttcaa tcataaattt ggcgtcttgc accgaacgca
    28381 cgtccccatt tccaataaag ggaatcttag tgatagcctt agaaactcgg gctaatgtct
    28441 catggtcgca ggttcctgta tacatttgct cacgggtacg accgtgcatg gcaagagcag
    28501 atacacctgc cgactcagcc gcaagggcat tttcaacagc aagtgaacta tccgcccaac
    28561 ctgtacgcat tttgacagtc agtggaatat ctaaaacaga cgtgacttcc ttgacaatgt
    28621 ggtaaatctt atcagggtca cggagccact tggcaccagc ctcgtttttg acaactttat
    28681 taacagggca gcccatatta atatcaacaa tatcggcctt ggtattggtt tgaatgaaat
    28741 cagctgcacg tttcaaccct tctgcgtcac caccaaataa ttgaatggac atagggtgct
    28801 cattttcatc aatatggagc atgtgaaggg tcttttcgtt gttgtagagc agcccttttt
    28861 cggaaatcat ttccataacc accaaaccag caccaaattc tttagcgatg gtacgaaagg
    28921 cagagttggt cacgccagcc atgggagcaa ggacagtgcg gtgagggatt tccacatcac
    28981 caatcctaaa ggaagaatta agctttatca ttgatgaggg cctccaaatc actttcatta
    29041 aattggtact tggtaccaca aaattggcaa acaatctcag cacccttatc ttcgtcaatc
    29101 atggcctgta aatctgcttt tggcaaagtc attagggctg cttcaaaacg ttctctagaa
    29161 cagtcacact gaaaactcag aggttcttca gaaagacgtt tgtaaggttc atctccatag
    29221 atggcctcca aaagggaatc cacatgattt ttggaagcta gtaggtgaga aatggcaggc
    29281 atttcttgca ggcgtttttc atagcgagca atctcttctt cagaagctcc tggtagcacc
    29341 tgcaccataa agccaccagc aaccttaacc ttatcatttt catctaaaag cacattaagt
    29401 ccgattgcag atggtgtttg ctctgattcg gttaagtagt aggcaaaatc ctcaccaatt
    29461 tctccagtaa taagaggcgt tgttgaggtg taagggttac ctgtgccata atcaataatc
    29521 gtcacaaaat gaccattccc cataaaaggc ccaacaagga cttcacctgt tgcggtcttt
    29581 ttaatatcga caccagtatt ttgaatgtaa cctttcacat gtcctttggt atctgccaca
    29641 gagataatgt gtccaaaaga agaatcacca atcactttga cggtgatttt actatcgcct
    29701 ttttgattag ccgccaaaat ctggttggcg atcaaggtac ggccaagcgc aacagtagac
    29761 gatgacagcg tgttgtgttt ttcctgagct aatgcaaccg tctcagtgct atcaaggaca
    29821 taagccctaa aagcccctga ttgtgctatt gatttaatta ttttatccat aacttagatt
    29881 atagcataaa gtgtaaaact tgtattgaca ggattgcttg aaaaatcaat acagatagac
    29941 agtaaaaaat cccagagaat gactcgggat taagttaagg tgtggtctaa agtcgcgcaa
    30001 tgtggtgaca tggcgcttat gttaattgtt tggttaaatc agcttggaat ttttcctctt
    30061 taacttgata catcaattct tggatagaca gaatcgattc atcaaaagat atttcagcaa
    30121 cagcaattcc ttttgtaagc tcatgctgaa caaaaggaat cagttggctg tgagtgatga
    30181 ctaaatctgg ttttaaatca ggaatttgat aaacattatc ttgcaataga taataggaat
    30241 gaaaatcaat gcttttatcc gagaaatacc ttggaaaaga atccgttagg agatgagcat
    30301 tgataaaatt actggctacg aaaacaacaa ctaaaggagg ttggatattt cttagaattt
    30361 gctcgacata gtggcaaaaa agatgaaaat gcttatggtt caagtcacgc ttaccaggaa
    30421 gtttggccat ccattcttcg acaattaact ttaaggacgt atagagtttt tggtttcctt
    30481 tatagtacgg agaaacgaat aagttggtct caggaataaa atgttgcaga ttaaacaaga
    30541 atgattttga aaaaaacata agagctttta ctaaactagc cttttgctct tttaggttag
    30601 gtaaaagagt gatgatagga tttaaaagca ggcgaaaagt atcattttct tcaaaaagtt
    30661 gacaacattg tctgatatgc tcaggtgtcc attgtaagct cgcaaaagaa ttattagcgg
    30721 tgatataaat taaatagagg tagtccaaat ctcccgctga aaagtttagt tggcagtaag
    30781 tttcgataat atcatggcta ctttttttca aagaatcgta gacaaaaagt ttttttaatt
    30841 gttgaaaaat tctggtttgg ggaatagtta ccgaaaattg atgccgcttc cacgataaag
    30901 ccaataaaat gtcatagaaa gaaaacgatt ccgataacca aggagaggtt ttaaggtggg
    30961 tggaactatg ggataaaaag ctatgaatag tgtttttgtc ttgctgcgtc aagtcataaa
    31021 ctttaatgcc aaacttacta tatagcagag cgatgaggta acggatgcga tattcctcac
    31081 cgacaatctt gttcttagag agttttaatt caaagtttct taataaagga atcaatgctt
    31141 cgcgcatccg ataagctgag gagtttgata aaaaatgact tcttgcaaaa tccgtaaggg
    31201 gacgagagtg ggaaccattt tttattaaaa acgctagtaa ttgtaagaca ttagatgatg
    31261 catagagttg gtaaagataa gtttctttaa aaggatgtgt aaattggcaa gatatcatcc
    31321 ttttttggat ggtcatagac agactaccag ggaaaaaggc attcagttcc tcacaataat
    31381 ggtttagttg taaaaaggtt aagccagttt tttctgctac ctcagttatt ggcaaataag
    31441 atgtcttaaa aaacaagata attaactgac attttgattc gattgatgat tccaagtatt
    31501 tttctatcaa ggaaagggac ctctcttcct aaacttagaa agccaaataa gtctttgata
    31561 agtgtattct cctatttcaa ttctatctaa gctaaaaata gaaatcaaat ctaatggttt
    31621 ttggtgaaaa gtcgaaacct tttgaaatag ctttaaagca atattttctc aaaaaatcat
    31681 tttcaaaaac attaatttgg tgaaaaatat aatcaaaaaa ttgtctttct tgacaataac
    31741 gtggtaagct catatatgtt tttgagagga gagaaaatga ataacaaaat gtttttgaat
    31801 aaagaagccg gttttttggc acacacaaaa agaaaaaggc gatttgctgt cactttagtg
    31861 ggagtctttt ttatgctttt ggtatgcgcg ggtgctatcg gttttggtca agtagcctat
    31921 gctgcggatg agaagactgt gccgaatcgt attaattcaa atcctgagtt tccttggtat
    31981 ggttatgatt cgtatagcgg aagattgtta agatatcaca atctgaaagt aaatctaaat
    32041 ggaagtaagg agtatcaagc gtattgtttt aacctgaaaa ggtttgagcc aaaaaaagaa
    32101 gaaagtagca gtcctaattg gtataaaaaa ttagatggga gtacagaaac ttttaaaaaa
    32161 tacgctgaaa accctaggtt tagtggagag gaattaagac gacatatatt gaaggttctc
    32221 tacaatggat atcctaatag taatgaaata atgaagggga tagaccctct caacgctatc
    32281 ttagtaacac aaaatgccat atggtattac tcggatagtg caccgattaa tgatattaat
    32341 aacttcttta ctagtgaagc caatgatctt aatataccac ctcagcagct aacgttaatg
    32401 cgtgaagctc tgagaaaact aatttcctct gatgaaaatt tggttaaaca agttccatcg
    32461 aactttaaac ttagtatttt tgagtcttct gataagtcct accaaaatct tttaagtgct
    32521 gaatatgtac ctgatgatcc tcctaaacct ggtgatacgt cagaacataa tcctaaaact
    32581 cccgagttgg atggcactcc aattcccgag gacccaaaac gtccagatga gagttcagaa
    32641 cctgcgcttc ccccattaat gccagagcta gatggtgaag aagtcccaga agttccaagc
    32701 gagagcttag aacctgcgct tcccccatta atgccagagc tagacggtga agaagtccca
    32761 gaagttccaa gcgagagctt agaacctgcg cttcccccat taatgccaga gctagatggt
    32821 gaagaagtcc cagaagttcc aaacgagagc ttagaacctg cgcttccccc attgatgcca
    32881 gagctagatg gccaagaagt cccagaagtt ccaagcgaga gcttagaacc tgcgcttcct
    32941 ccattaatgc cagagctaga cggtgaagaa atcccagaag ttccaagcga gagcttagaa
    33001 cctgcgcttc ccccattaat gccagagtta gatggtcaag aagtccctga aaaacctagt
    33061 gttgacttac ctattgaagt tcctcgttat gagtttaaca ataaagacca gtcacctcta
    33121 gcgggtgagt ctggtgagac ggagtatatt accgaagtct atggaaatca acagaaccct
    33181 gttgatattg ataaaaaact tccgaatgaa acaggttttt caggaaatat ggttgagaca
    33241 gaagatacga aagagccaga agtgttgatg ggaggccaaa gtgagtctgt tgaatttact
    33301 aaagacactc aaacaggcat gagtggtcaa acaactcctc aggttgagac agaagatacg
    33361 aaagagccag gagtgttgat gggaggccaa agtgagtctg ttgaatttac taaagacact
    33421 caaacaggca tgagtggttt cagtgaaaca gtgactatta ttgaagatac gcgtccgaag
    33481 ttagtgttcc attttgacaa taatgagccc aaagtggaag agaatcggga aaaacctaca
    33541 aaaaatataa cacccatcct tcctgcaaca ggagatattg gaaatgtttt agcctttctt
    33601 ggaatcctta ttttgtcagt actttctatt tttagccttt taaaaaacaa acaaaacaat
    33661 aaagtctgac gtaaaagtgt tccataagaa ataatgcgca aatatgctga atagtggata
    33721 actgctacag tcaagacaaa tgttaattca aaaggtacta cttatacatc tgataataat
    33781 aaggtgacag ataattcaga gcaagtagga tggctaaaaa atggtgtatt ctatgtataa
    33841 tagacttaca agaaatcaag ttattgttaa acgtcgtaaa gcttaacgct ttcaaaagtc
    33901 gaaatcaatc gagactgtct ttaggcagtc tcgattttta ttgataagga actgcaatga
    33961 cagaaagact aaaaaatcta gggctactct tattattttt tttgggaaca gccacttttc
    34021 tttaccctac gctaagtagt cagtggaatg tctatcgtga tcgttaattg ttatcaactt
    34081 atcacaaaca agtgactcaa aagaagccct cagaaatgga cgagatgtgg caaaaggcta
    34141 aggcgtataa cgctaggctt gggattcagc ccgttccaga tgctttttca tttagggatg
    34201 gcattcatga taaaaactac gaaagcctac ttcaaattga aaacaatgat attatggaat
    34261 atgttgaagt gtcctccatt aaagtgacgt tacccatata ccactatacg acagacgagg
    34321 tgctaactaa aggagcaggt cacttatttg gaagtgcctt accagttggt ggcgacggga
    34381 ctcacacggt tatttctgct catagaggcc ttccatcggc agaaatgttt actaatttga
    34441 atttagtgaa aaggggagat actttttact ttcgtgtgtt aaataaagta ttggcttata
    34501 aagttgatca gatactaact gttgaaccag atcaagtcac atctctttct gaggtaatgg
    34561 gaaaagatta tgctactctg gttacctgca caccatatgg tgttaatacc aagcgtctat
    34621 tggtcagagg tcatagaatt gcatttcatt acaaaaagta tcaacaggct aaaaaagcaa
    34681 tgaaactcgt ggataaatca agaatgtgga cagaagtagt atgtgctgct ttcggggtgg
    34741 ttatagctat tattttagta tttatgtatt caaagatgac tgataaaaaa gtgattaaaa
    34801 actaacttgc cctgaatctt cattatcgta ctgaaactgt tgtaaaagta aaataatctg
    34861 gtagttacta tcccctttga tgaagtttaa ttaaatctca tcaagagaaa aatattaggc
    34921 ggttacaaat gattttccca aaaattattt tttggaacgc ataatatgga aaaaaagatg
    34981 ataagaacaa ctgttttaaa catcaaataa atgatatagt agctatgaaa tagcattgtg
    35041 actgtccggt aaagggatgg gactgaagat tttattcaga aggagaggga atgaataaca
    35101 aaaaattgca aaagaagcaa gatgctcctc gggtatcaaa cagaaagcca aaacaattaa
    35161 ctgtcacttt agtgggagta tttttaatgt ttttgacctt ggtaagttcc atgagaggtg
    35221 ctcaaagcat atttggagag gaaaagagaa ttgaagaagt cagtgttcct aaaataaaaa
    35281 gtccagatga tgcctaccct tggtatggct atgattcata tgactctagt catccttact
    35341 atgaacgttt taaagtagca catgatttaa gggttaattt aaatggaagt aagagctacc
    35401 aagtatattg ctttaatatc aattctcatt atccgaatag aaaaaatgct ttttctaaac
    35461 aatggtttaa gagagttgat gggacaggtg atgtgttcac aaattatgct cagacaccta
    35521 agattcgtgg agaatcattg aataataaac ttttaagtat tatgtacaac gcttatccta
    35581 aaaatgctaa tggctatatg gataagatag aaccattaaa tgctatttta gtaactcaac
    35641 aagctgtttg gtactattct gacagttctt atggtaatat aaaaacgtta tggacatctg
    35701 agcttaaaga cggaaaaata gattttgaac aagtaaaatt aatgcgtgaa gcttactcaa
    35761 aactaattag tgatgattta gaagaaacat ctaaaaataa gctacctcaa ggatctaaac
    35821 tgaatatttt tgttccgcaa gataaatctg ttcaaaattt attaagtgca gagtacgtgc
    35881 ctgaatcccc tccggcacca ggtcagtctc cagaaccgcc agtgcaaaca aaaaaaacat
    35941 cagtcattat cagaaaatat gcggaaggtg actactctaa acttctagag ggagcaactt
    36001 tgcgtttaac aggggaagat atcctagatt ttcaagaaaa agtcttccaa agtaatggaa
    36061 caggagaaaa gattgaatta tcaaatggga cttatacctt aacagaaaca tcatctccag
    36121 atggatataa aattgcggag ccgattaagt ttagagtagt gaataaaaaa gtatttatcg
    36181 tccaaaaaga tggttctcaa gtggaaaatc caaacaaaga agtagcagag ccatactcag
    36241 tggaagcgta cagcgatatg caagatagta actatattaa tccagaaacg ttcactcctt
    36301 atgggaaatt ttattacgct aaaaataagg ataaaagttc acaagttgtc tactgtttta
    36361 atgctgattt acactctcca cctgaatcag aggatggagg aggaactata gatcctgata
    36421 ttagtacgat gaaagaagtc aagtacacac atacggcagg tagtgatttg tttaaatacg
    36481 cgctaagacc gagagataca aatccagaag acttcttaaa gcacattaaa aaagtaattg
    36541 aaaaaggcta caataaaaaa ggtgatagct ataatggatt aacagaaaca cagtttcgcg
    36601 cggctactca gcttgctatc tattacttta cagacagcac tgacttaaaa accttaaaaa
    36661 cttataacaa tgggaaaggt taccatggat ttgaatctat ggatgaaaaa accctagctg
    36721 taacaaaaga attaattaat tacgctcaag ataatagtgc ccctcaacta acaaatcttg
    36781 atttcttcgt acctaataat agcaaatacc aatctcttat tgggacagaa taccatccag
    36841 atgatttggt tgacgtgatt cgtatggaag ataaaaagca agaagttatt ccagtaactc
    36901 acagtttgac agtgaaaaaa acagtagtcg gtgagttggg agataaaact aaaggcttcc
    36961 aatttgaact tgagttgaaa gataaaactg gacagcctat tgttaacact ctaaaaacta
    37021 ataatcaaga tttagtagct aaagatggga aatattcatt taatctaaag catggtgaca
    37081 ccataagaat agaaggatta ccgacgggat attcttatac tctgaaagag actgaagcta
    37141 aggattatat agtaaccgtt gataacaaag ttagtcaaga agctcaatca gcaagtgaga
    37201 atgtcacagc agacaaagaa gtcacttttg aaaaccgtaa agatcttgtc ccaccaactg
    37261 gttttactac tgatggtgga acctatctgt ggttattatt gcttgtccca tttggtttgt
    37321 tagtgtggtt ctttggtcgt aaaggactaa aaaatgacta attacctaaa tcgcttaaat
    37381 gagaatccac tatttaaagc tttcatacgg ttagtactta agatttctat tattggattt
    37441 ctaggttaca ttctatttca gtatgttttt ggcgtcatga ttgttaacac aaatcagatg
    37501 agtcctgctg taagtgctgg tgatggagtc ttatattatc gtttgactga tcgctatcat
    37561 attaatgatg tggtggtcta tgaggttgat aacactttga aagttggtcg aattgccgct
    37621 caagctggcg atgaggttaa ttttacgcaa gaaggaggac tgttgattaa tgggcatcca
    37681 ccagaaaaag aggtccctta cctgacgtat cctcactcaa gtggcccaaa ttttccctat
    37741 aaagttccta cgggtacgta tttcatattg aatgattatc gtgaagaacg tttggacagt
    37801 cgttattatg gggcgttacc catcaatcaa atcaaaggga aaatctcaac tctattaaga
    37861 gtgagaggaa tttaaaaaaa tttggagaga gagaaaatga aaaaaaataa attattactt
    37921 gctactgcaa tcttagcaac tgctttagga acagcttctt taaatcaaaa cgtaaaagct
    37981 gagacggcag gagttgtaac aggaaaatca ctacaagtta caaagacaat gacttatgat
    38041 gatgaagagg tgttaatgcc cgaaaccgcc tttactttta ctatagagcc tgatatgact
    38101 gcaagtggaa aagaaggcga cctagatatt aaaaatggaa ttgtagaagg cttagacaaa
    38161 caagtaacag taaaatataa gaatacagat aaaacatctc aaaaaactaa aatagcacaa
    38221 tttgattttt ctaaggttaa atttccagct ataggtgttt accgctatat ggtttcagag
    38281 aaaaacgata aaaaagacgg aattaggtac gatgataaaa agtggactgt agatgtttat
    38341 gttgggaata aggccaataa cgaagaaggt ttcgaagttc tatatattgt atcaaaagaa
    38401 ggtacttcta gtactaaaaa accaattgaa tttacaaact ctattaaaac tacttcctta
    38461 aaaattgaaa aacaaataac tggcaatgca ggagatcgta aaaaatcatt caacttcaca
    38521 ttaacattac aaccaagtga atattataaa accggatcag ttgtgaaaat cgaacaggat
    38581 ggaagtaaaa aagatgtgac gataggaacg ccttacaaat ttactttggg acacggtaag
    38641 agtgtcatgt tatcgaaatt accaattggt atcaattact atcttagtga agacgaagcg
    38701 aataaagacg gttacactac aacggcaaca ttaaaagaac aaggcaaaga aaagagttcc
    38761 gatttcactt tgagtactca aaaccagaaa acagacgaat ctgctgacga aatcgttgtc
    38821 acaaataagc gtgacactca agttccaact ggtgttgtag ggacccttgc tccatttgca
    38881 gttcttagca ttgtggctat tggtggagtt atctatatta caaaacgtaa aaaagcttaa
    38941 gtgattagtc aaagaatgat gatgacaatt gtacaggtta tcaataaagc cattgatact
    39001 ctcattctta tcttttgttt agtcgtacta tttttagctg gttttggttt gtgggattct
    39061 tatcatctct atcaacaagc agacgcttct aatttcaaaa aatttaaaac agctcaacaa
    39121 cagcctaaat ttgaagactt gttagctttg aatgaggatg tcattggttg gttaaatatc
    39181 ccagggactc atattgatta tcctctagtt cagggaaaaa cgaatttaga gtatattaat
    39241 aaagcagttg atggcagtgt tgccatgtct ggtagtttat ttttagatac acggaatcat
    39301 aatgatttta cggacgatta ctctctgatt tatggccatc atatggcagg taatgccatg
    39361 tttggcgaaa ttccaaaatt tttaaaaaag gattttttca acaaacataa taaagctatc
    39421 attgaaacaa aagagagaaa aaaactaacc gtcactattt ttgcttgtct caagacagat
    39481 gcctttgacc agttagtttt taatcctaat gctattacca atcaagacca acaaaggcag
    39541 cttgttgatt atatcagtaa aagatcaaaa caatttaaac ctgttaaatt gaagcatcat
    39601 acaaagttcg ttgctttttc aacgtgtgaa aatttttcta ctgacaatcg tgttatcgtt
    39661 gtcggtacta ttcaagaata acgaaaggag gagacttttg agaaaatatt ggaaaatgtt
    39721 attttctgtc gtaatgatat taaccatgct ggcctttaat cagactgttt tagcaaaaga
    39781 cagcactgtt caaactagca ttagtgtcga aaatgtctta gagagagcag gcgatagtac
    39841 cccattttcg attgcattag aatcaattga tgcgatgaaa acaatagaag aaataacaat
    39901 tgctggttct ggaaaagcga gcttttcccc tctgaccttc acaacagttg ggcaatatac
    39961 ttatcgtgtt tatcagaagc cttcacaaaa taaagattat caagcagata ctactgtatt
    40021 tgacgttctt gtctatgtga cctatgatga agatgggact ctagtcgcaa aagttatttc
    40081 tcgaagggct ggagacgaag aaaaatcagc gattactttt aagcccaaac ggttagtaaa
    40141 accaataccg cctagacaac ctgacatccc taaaacccca ttaccattag ctggtgaagt
    40201 aaaaagttta ttgggtatct taagtatcgt attactgggg ttactagttc ttctttatgt
    40261 taaaaaactg aagagtaggc tataaaaccc atttctagtt gctctatttt tataatgaaa
    40321 cttattgaca tctccatagt cttgcttgac tttggagatg tttttctatg ctgataggtt
    40381 tttgtaccat ataagataat gattgatgaa aagagtgtct tgaattctta aatattatct
    40441 cggtatttag caagatagtc tttt
//
LOCUS       DAUCXI010000016        39317 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.016, whole genome shotgun sequence.
ACCESSION   DAUCXI010000016 DAUCXI010000000
VERSION     DAUCXI010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39317
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.016"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(1..444)
                     /locus_tag="VGY43_000835"
                     /pseudo
     CDS             complement(1..444)
                     /locus_tag="VGY43_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370026.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            complement(961..1593)
                     /locus_tag="VGY43_000836"
     CDS             complement(961..1593)
                     /locus_tag="VGY43_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEQ4302035.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLKTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDS
                     SWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
     gene            complement(1593..2357)
                     /locus_tag="VGY43_000837"
     CDS             complement(1593..2357)
                     /locus_tag="VGY43_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEQ4302036.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQSMLTNQFHVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQVTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            complement(2357..3109)
                     /locus_tag="VGY43_000838"
     CDS             complement(2357..3109)
                     /locus_tag="VGY43_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEQ4302037.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGG
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFKTDFVKKLHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCAFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQIISDGQLNAQAMIEWRAIKQTESEID"
     gene            complement(3119..4249)
                     /locus_tag="VGY43_000839"
     CDS             complement(3119..4249)
                     /locus_tag="VGY43_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEQ4302038.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FESYDIHDLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIY
                     ALPGQTLEQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGISFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            complement(4312..4953)
                     /locus_tag="VGY43_000840"
     CDS             complement(4312..4953)
                     /locus_tag="VGY43_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302039.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTPKQDI
                     QKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKGLAYHLLSTVAANQVFAAAV
                     NEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLTD
                     MQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP"
     gene            complement(5077..6432)
                     /locus_tag="VGY43_000841"
     CDS             complement(5077..6432)
                     /locus_tag="VGY43_000841"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEQ4302040.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGS
                     THPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAI
                     ANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
                     N"
     gene            complement(6486..7442)
                     /locus_tag="VGY43_000842"
     CDS             complement(6486..7442)
                     /locus_tag="VGY43_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEQ4302041.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSYPGTVSVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVNKVEVTSDESTIALIDHVVAKLPDDQVLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            complement(7439..8290)
                     /locus_tag="VGY43_000843"
     CDS             complement(7439..8290)
                     /locus_tag="VGY43_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEQ4302042.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVSLPWYKK
                     ILGGKSK"
     gene            8397..9740
                     /locus_tag="VGY43_000844"
     CDS             8397..9740
                     /locus_tag="VGY43_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEQ4302043.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     GRQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFICLNCGFKRPQLDYRLTELTTITNHSSEFIIDGQDYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI"
     gene            9740..10531
                     /locus_tag="VGY43_000845"
     CDS             9740..10531
                     /locus_tag="VGY43_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEQ4302044.1"
                     /translation="MTYTSLKSPENQDYIYDLTIAHLYGNLMNTYGDNGNILMLKYVA
                     EKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTALKKKYGSAISLSSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(10640..11629)
                     /locus_tag="VGY43_000846"
     CDS             complement(10640..11629)
                     /locus_tag="VGY43_000846"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ4302045.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILTKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIGRNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFERLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            11862..14279
                     /gene="hylA"
                     /locus_tag="VGY43_000847"
     CDS             11862..14279
                     /gene="hylA"
                     /locus_tag="VGY43_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEQ4302046.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMIGQGTAIYADTLTSNSEPNN
                     TYFQTQTLTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KDAQNIIKSYQGPDHENRTYLWEHAKDYSASTNITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYPY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEANSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSPIEADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     NDTFVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTS
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKHPYHAYVNNQPVDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPT
                     TLSISKALQTGQWQNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYGKKATMFSNHNLSHQGFYSFPH
                     PVKQNQQ"
     gene            complement(14952..16715)
                     /gene="lpdA"
                     /locus_tag="VGY43_000848"
     CDS             complement(14952..16715)
                     /gene="lpdA"
                     /locus_tag="VGY43_000848"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEQ4302047.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVP
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAI
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            complement(17046..18455)
                     /locus_tag="VGY43_000849"
     CDS             complement(17046..18455)
                     /locus_tag="VGY43_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEQ4302048.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKIVRPAGDTVLVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPAVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKVAAEMGIDLGQVPGTGPKG
                     RVHKEDVENFKGAQPKASPLARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKP
                     AEAKAPAAKEEKVVDLPEGVEYKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKLEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(18640..19638)
                     /locus_tag="VGY43_000850"
     CDS             complement(18640..19638)
                     /locus_tag="VGY43_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEQ4302049.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            complement(19697..20665)
                     /locus_tag="VGY43_000851"
     CDS             complement(19697..20665)
                     /locus_tag="VGY43_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEQ4302050.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLSYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            complement(20950..22857)
                     /locus_tag="VGY43_000852"
     CDS             complement(20950..22857)
                     /locus_tag="VGY43_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ4302051.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDQTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQDLTRLMTDYDLLTEHFRQQGGFTYESDIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPHGLDRYVGNYSRFLTLKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAI
                     GYNQHVLSEPINLDVHKLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVETG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHASNDTAQLIAWQKEWDQLDQEQETLME
                     EWETIAEQIES"
     gene            complement(22903..23229)
                     /locus_tag="VGY43_000853"
     CDS             complement(22903..23229)
                     /locus_tag="VGY43_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302052.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            complement(23259..24044)
                     /locus_tag="VGY43_000854"
     CDS             complement(23259..24044)
                     /locus_tag="VGY43_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEQ4302053.1"
                     /translation="MANIAIEYHSVVLGMERKVNVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRAAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGN
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADF
                     QAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            complement(24177..25838)
                     /locus_tag="VGY43_000855"
     CDS             complement(24177..25838)
                     /locus_tag="VGY43_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ4302054.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIVYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            complement(26042..26800)
                     /locus_tag="VGY43_000856"
     CDS             complement(26042..26800)
                     /locus_tag="VGY43_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302055.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSQSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            complement(26797..27666)
                     /locus_tag="VGY43_000857"
     CDS             complement(26797..27666)
                     /locus_tag="VGY43_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302056.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCFPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERFFKGVRLTR"
     gene            complement(27843..28061)
                     /locus_tag="VGY43_000858"
     CDS             complement(27843..28061)
                     /locus_tag="VGY43_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302057.1"
                     /translation="MLLTGKIFLQLLLLRINTKTCDIKGQEKTIKNTLTEVNLDAKSD
                     NRLEDVMVIFIIFSFKMLYFRHVKNLAF"
     gene            complement(28012..29010)
                     /locus_tag="VGY43_000859"
     CDS             complement(28012..29010)
                     /locus_tag="VGY43_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ4302058.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANQQNITIGIL
                     QLVTHEALDDIKRGIEDQLKKQKPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAAASKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAINREDFPSASFIEN"
     gene            29364..31016
                     /gene="fbp54"
                     /locus_tag="VGY43_000860"
     CDS             29364..31016
                     /gene="fbp54"
                     /locus_tag="VGY43_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HEQ4302059.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGRIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRLQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIEPPKTAAVNPFTITDVPLFEILQTQELTVKRLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSDMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGKTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLF"
     gene            complement(31075..32322)
                     /locus_tag="VGY43_000861"
     CDS             complement(31075..32322)
                     /locus_tag="VGY43_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEQ4302060.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLV
                     MADLYDLEGLTEVAREKLLQAVAISSEPLVIFGLAEIDMSLQYFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLMYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDSVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(32312..33493)
                     /locus_tag="VGY43_000862"
     CDS             complement(32312..33493)
                     /locus_tag="VGY43_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ4302061.1"
                     /translation="MSLIPEKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            complement(33551..34027)
                     /locus_tag="VGY43_000863"
     CDS             complement(33551..34027)
                     /locus_tag="VGY43_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEQ4302062.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY"
     gene            complement(34631..35341)
                     /gene="speh"
                     /locus_tag="VGY43_000864"
     CDS             complement(34631..35341)
                     /gene="speh"
                     /locus_tag="VGY43_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeH"
                     /protein_id="HEQ4302063.1"
                     /translation="MRYNCRYSHIDKKIYSMIICLSFLLYSNVVQANSYNTTNRHNLE
                     SLYKHDSNLIEADSIKNSPDIVTSHMLKYSVKDKNLSVFFEKDWISQEFKDKEVDIYA
                     LSAQEVCECPGKRYEAFGGITLTNSEKKEIKVPVNVWDKSKQQPPMFITVNKPKVTAQ
                     EVDIKVRKLLIKKYDIYNNREQKYSKGTVTLDLNSGKDIVFDLYYFGNGDFNSMLKIY
                     SNNERIDSTQFHVDVSIS"
     gene            complement(35367..36044)
                     /gene="spei"
                     /locus_tag="VGY43_000865"
     CDS             complement(35367..36044)
                     /gene="spei"
                     /locus_tag="VGY43_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEQ4302064.1"
                     /translation="MSSVGVINLRNLYSTYDPTEVKGKINEGPPFSGSLFYKNIPYGN
                     SSIELKVELNSVEKANFFSGKRVDIFTLEYSPPCNSNIKKNSYGGITLSDGNRIDKKN
                     IPVNIFIDGVQQKYSYTDISTVSTDKKEVTIQELDVKSRYYLQKHFNIYGFGDVKDFG
                     RSSRFQSGFEEGNIIFHLNSGERISYNLFDTGHGDRESMLKKYSDNKTAYSDQLHIDI
                     YLVKFNK"
     gene            complement(36318..37652)
                     /locus_tag="VGY43_000866"
     CDS             complement(36318..37652)
                     /locus_tag="VGY43_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEQ4302065.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLRTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
     gene            complement(37764..37949)
                     /locus_tag="VGY43_000867"
     CDS             complement(37764..37949)
                     /locus_tag="VGY43_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302066.1"
                     /translation="MNNWFKKVAIKTIKTMAQTAVGLIGSSVLITDINWPTMLSAVLL
                     SGLTCILMNVSQIKEEE"
     gene            complement(37946..38242)
                     /locus_tag="VGY43_000868"
     CDS             complement(37946..38242)
                     /locus_tag="VGY43_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302067.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANEFAMAQLKD
                     SIKELAYELKNLDREREITKKIIDRHEERLGRVEDEVIINKERIITLFKKGEEK"
     gene            complement(38252..38863)
                     /locus_tag="VGY43_000869"
     CDS             complement(38252..38863)
                     /locus_tag="VGY43_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ4302068.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITTEDGSVISQLVKQDLIS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHMLTSGGKIDPDIYKGLLELIEPAKKGEYQAYDVFTVVDESHEEQ
                     AGEGNLVFVHVNEPFTYDKQTLEELESEDKVTVIKYADLVKQD"
     gene            complement(38866..39294)
                     /locus_tag="VGY43_000870"
     CDS             complement(38866..39294)
                     /locus_tag="VGY43_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEQ4302069.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKINE
                     YAKDETDLIDMYAAKDKDDKFVIDEHKNIKLADPAKLDELNDLLNELADEEIVIKGGE
                     YSKRFIDFLEYLAESEDEFTAQEIIIVDSILEQYEGSKGE"
BASE COUNT        12022 a         8243 c         6729 g        12323 t
ORIGIN      
        1 cggattatct tgcaagagaa tagcggagct accgagatta ctttgatgag cccaaaggac
       61 aatctcacgc ctagcagagt ctcttgaatg agacccatac gccatgttaa aaatacctcc
      121 atcatcacca agagcctgag caaaattccc acgaatggtt ccgcaaagag catccgtagg
      181 attggttact ctcatcatgc atggttcaaa aagacaaaac caccttagtc cccaagaatt
      241 atcccaatta aaacaggacc acttgtcatg taagctttaa gtttaggatc aaaaggttta
      301 tcaccaaggt ctcgtcgtgc ttagccaagt atttcgaact agcttgtctt agctcgaatc
      361 gctcaaacgt aaatcttagg cgttcaatcc accgcaaaat ctctccaact aaccctctcg
      421 cttaacccca tctggcttaa tcataaaaaa atgttggttc catcactcta ctcttctttt
      481 gtctattata acatgaaaac gctttaacaa aaagaatatg aaggtatccg actgctggta
      541 tgaaccctct ttctcaagtt atcattggca atgttgaatg gagaccactc aaaacagcat
      601 agctctaaaa cccagagatg gcaaagattc ggtttactct agttttggga ccactcaaaa
      661 cagcatagct ctaaaaccca tctaaaatta tttgtgggct gtctgacgtt ttgggaccat
      721 tcaaaacaac atagctctaa aacgttcctg taattttgat ttgttccata ttgttttggg
      781 accattcaaa acagcatagc aagttaaaat aaggctagtc cgttatcaac ttgaaaaagt
      841 ggcaccgagt cggtgctttt tttgatactt ctattctact ctgactgcaa actaaaaaac
      901 aagcgctttc aaaacgcttg ttttatcatt tttagggaaa ttaatctctt aatcctttta
      961 tcattctaca tttaggcgct gccatcttgc taaacctact aagctccaca ggatgatttc
     1021 gtaaactatc ataaagaaaa ggaaacagtg caagaaaaag acttctggaa ggatccaaat
     1081 cacaggatct ttcaagggat caaagagcca gctgctatct cctacaaaaa gcacctgatg
     1141 aaaaagagta aaaaaatgtt caaacccaat gaaactagcc attagaccaa tcataagagg
     1201 aaacaaagct gctagtatta aaggtttttg aaggagccag aaacgtttgg tttttaacct
     1261 ttgtgtgaaa gtcttaaggg ttgggtaaag gaggccaaga aaaacgactt gagttaggtg
     1321 aaaaagccac ttcacatctg caaaatgctt gagtccgtct gctgatgagt gaaaattagc
     1381 aaattccaac cttgtcacaa aaggattggt gaggtaattt agtagtccgt tatagttatg
     1441 caagatagca tccttgctca taaaaacaac ttgttctaac tttagatggt ccacctcaag
     1501 aggataccac agccacgttg aatagatcgt tatgagaata gctaacgcta ataaccatac
     1561 ccagctacat agtaatttag tgttttctac catcacaacc tccactcatc aaggctagat
     1621 aggacatgat ctggctgaat tggtaaggtt ggtacctctt caggtctggt aaagcctgtt
     1681 gtcacgagga tcgttgcaat atcattttga atacctgcca tgatatcagt caagtaatta
     1741 tcgccaacca tgacggcttc agagcgctga atgcccaata cctctagtga tttattcata
     1801 atgatagcgt tgggcttgcc aataaaaaca ggttttacac gtgtggcagc ttctagtaag
     1861 gcattcaatg cacctgctcc tggcatcaaa ccacgttcgg ttggaatgtt taaatcagga
     1921 tttgtcccaa taaagagggc acctttttga atagctaagg tggctatagc caacatctca
     1981 taggtcacct gactgtctaa accaaccacc acgtaagcgg gattctcaag ttcttctacg
     2041 taacctgctg ctgcaatagc tgatttgagc cctgtttctc caataacgta agctgtcttg
     2101 ccacggttca tgtcattcat gtaatcgacg gttgccatgg tagccgtata aatggtctca
     2161 atgcctgtct caacatgaaa ctgattagtc agcatgcttt gcaccatttc gggtgttctt
     2221 gtggtattat tagtcactaa taaataggga atgccttttt cttgtaggcg tttgataaac
     2281 cgctcccctg ctggaatacg gtttttccct tggtaaatcg ttccgtctaa atcaattaaa
     2341 taacccttat aaggcactag tctatctcgc tttctgtttg tttaatcgct cgccattcaa
     2401 tcatggcttg ggcattcagc tgcccatctg agatgatttg atggtaagaa gttaattggt
     2461 ccaaatggta actggaagta atttgaccgc ctggtgagac ttctttaaca tatttcaaag
     2521 tcatcttaag aggctgatgc gtttttaaaa acgcacaccc caacacatca tacatccaat
     2581 ctaaatattt actgttgttg acatgaccat tcatatcaat atcaaaataa cgcacataat
     2641 aatcacgatc aattgattgt tctaaaagag gcattttagg aacacggtgt agctttttaa
     2701 caaaatcagt cttaaaaggc gctactaaat cttctggaat agttgccact tttcgcgtat
     2761 ctgggtttaa caaagcaaaa taggctaaga tatccactaa aagacccccc tcttgatcat
     2821 aaatataaaa ttggcgataa caaaaaaatt tattatagga aagggctttt gtttcaatgg
     2881 tgatggtttc ttgaaaatgt ggcaagcgat gaatagtgat ctcataatcc gttacaatcc
     2941 aaacaagctt gtaatcaact aaaagattgt tgttacttcg tcctaattgc gcagactgtc
     3001 taccagaaac catcaaacaa tagtctaata aaaggggcaa ttttatatct gatttgacat
     3061 cacataattc aaaaggaagt gtcaactcct cctgataact taatcccata atactctcct
     3121 aatctaatat aaaccgctca gcaacagaat cacctaagaa aagacccttt ttagtcattc
     3181 tgacaaaggc gtcatctttg acaagcagtc cttggttttg aagctcccta acaatatttc
     3241 cataacgctc ctcaaaagaa ataccaaatt tttcttggaa ccgctggatg gagactcctg
     3301 tctttttacg taagcccaaa aagagttcct cttccatcat ttcctctttg cgcagcactt
     3361 cttcatttag tctagcgttt cctgcttcaa ccgctttaag ataatgctgg atgggcaccc
     3421 gattttgata acgaatgcca ttaaggtaac ctgaagcccc tgcaccacat ccaaaatact
     3481 ccacattatc ccaatacatc aagttatggc gactttcaaa acctggtttg gtaaaattgg
     3541 aaatttcata atgctcaaaa ccattagctt ccatttctga aataatatac tcaaacattt
     3601 ctgcttccaa gtcttccgtt ggtaagttaa gtttaccacg ccgcattttg ttcataaaaa
     3661 cggtgtgatg ttccaaaata aggctataaa gactaagatg gggaatatca agtgccaaag
     3721 ctttagcaac attttccttg acttgttcta aggtttgacc tggcaaggca taaattaaat
     3781 caatggaaat attgtgaaag cctgcagttt ttaaattggc aatggtgcta taaatttgtt
     3841 cttcattatg gctacggcca atctgcttta attgcttgtt attaaaagtc tgcaccccca
     3901 aggaaatccg attgacagct gacctctgaa gcaccgcaat tttttctggc gtcaaatcac
     3961 caggatttgc ctcaattgtg aattcttcaa gatcatctaa attgaggttt cgttcaaggt
     4021 gatttaggag atactccaac tgtttagcag tgatagctgt aggcgtacct cctccaatat
     4081 aaagagtctt taagtcatga atgtcatagg attcgaattc ttgaatcaag gctttcaaat
     4141 aagcatcaac aggttgattt tggataaaga cttttgaaaa atcgcaataa taacaaattt
     4201 gtgtgcaaaa aggaatgtgc acataggctg aagtaggttt ttttgacatg gtcttattat
     4261 accactttga tgataaaatg tttctatgaa taaaccattt cccttgattc ttcatggctt
     4321 ggaaaagtat tttacgagct gacaaacgtc agagtcattt tcgtttcctg gcttgcaacc
     4381 cttagctagc aaaacaaacc cttgttcttg gtaaaaaagc ttgcttgatt cttgactgac
     4441 cataatgctt aaagaaggga gtttctcttg catatctgtc agaagatatg tctggacagc
     4501 ctccacaata gctgctggaa cctcgttttc tgtcactgtt tcaagaatcc ctaaagtcat
     4561 ttctagaaat tcaccctttt cttgaagaat cacaaaggct actcttgctc catttcgaag
     4621 cacttgaaaa agcgtctgat cctcgttaac agcagccgca aacacttgat tagctgcaac
     4681 tgtcgataac aaatgataag ctaggccttt atctgctagc aattgctctg ctgtttttct
     4741 tgtcacaggc atcacataaa aagatggggt atctagtaat cgttcaaaat ttttagttaa
     4801 ctgcttgatg cggcgctttt gaatatcttg ttttggtgtt tgataaacat atgaagcata
     4861 accttcctga aattcaggaa tcatatctaa gtaaagtgtg gctgcaaaag gaggcagtaa
     4921 gtccgctagt ttttcgattt gctgttttgt catccgatat cctttctctt ctactttagc
     4981 aatttataaa aagagacttg ggctaaacgc cccaagcctc tttccaattg ttgacagaag
     5041 ccttagaaat aaggtttctt gtttgtactc aactcgttag ttatcgcatc cgatttctgt
     5101 acggacgaca tcagcaatag tatcgacata ataatcaact tcggcatctg ttggcgcctc
     5161 tgccatgaca cgaagaagag gttctgtacc acttggtctc acgagaatac gaccattacc
     5221 agccatttca tcctccattt ttgcaatgat gttcgcaata gctggaactt ccatagcacg
     5281 gtctttcatg ctgttttcca cacgaatatt caccagtttt tgagggtaaa tggttacttc
     5341 agcagctaat tccgaaagtg atttcccggt ttccttcatc accttggcta attggatagc
     5401 tgtcaactga ccatctccag tggtattgta gtccatgata atgacatgac ctgattgttc
     5461 accaccgaga ttgtatcctg agctacgcat ttcttcaacc acatagcggt ctccaactgc
     5521 tgtaattgct ttattaatac cttgtttatc taaagcttta tgaaaaccga ggttagacat
     5581 caccgttgtg acaatggtat tgtgagcaag aagccctttt tctgacaaat atttaccaat
     5641 gataaacata atacgatcac cgtcaacaat ctcaccagtt tcgtccacgg caatcagacg
     5701 gtcgctatcg ccatcaaagg ctaaaccaag atctgctcct gtttccttaa ctaactcttg
     5761 aagttgttct ggatgcgttg aaccaacacc gtcattaata ttaagaccat ttggtttttc
     5821 gccaatgaca gcaatttctg catttaaatc taaaaagaca tcacgtgctg acactgaagc
     5881 agctccatta gcagtgtcta aggcaactgt cataccgctt aagtcagtac ctgttgttac
     5941 caagaacttt tcatatttac gaagtccttc tggataatct accaaggttc caagtccttc
     6001 tgcactcggg cgaggaagcg tgtcctccgg agcatctaag agagcttcaa tttccaattc
     6061 ttggtcatca gctaacttaa acccatcatt cccaaagaat ttgatgccat tgtcaagcgc
     6121 agggttatga cttgcagaaa tcatcacacc tgcacttgct ttttctgttc taactaaata
     6181 agagacacca ggtgtcgcta aaacaccaag tttataaact tcaataccaa cagatagtag
     6241 accagcaatc aaggctgact ccaacatttc tcctgaaata cgggtgtcac gcgccacaaa
     6301 aactttaggt ctttcggtct catgttgact taaaacataa ccaccgaatc ggcccagttt
     6361 aaaagctaac tcaggtgtca gctcaacatt tgcttcacca cgaacaccat ctgttccaaa
     6421 atattttccc ataatttata taagcctaat ggcttcctcc attcaatttt cctagttatt
     6481 atccattatt ttttggtggt tgtcaactga acggtcacta ctgacggctc aattgacacc
     6541 tgactagaag acaaactcac ggtcttacta gtatttttag tgacatcaga aatgttaact
     6601 tctgcaataa tttcatcaat atcttctaag acctctcgac tacctgagat aacagctgtt
     6661 tgttttgaca atttgtattg aatatctgat aagctatcat ccatcatccc cactgcctca
     6721 actctaatcg ggactgattt cgttattttt tttacagcaa ctgataaatt tgtttttgca
     6781 ggatcaattg cacttgctaa aatagttcca tcagctgaga cagcttgtaa ggtcactcga
     6841 ctactataat tcctatctaa cacttgatca tcaggtaact ttgccacaac gtgatcaatt
     6901 aaagcaatgg tagattcatc actggtcact tcaaccttat taacccccgt ttcaattttg
     6961 ctaatttcat aaccatttgc aatttgttta gcatcaacgc ttcctctaac aggaaatacc
     7021 ttagattctt ttttgccaat tgtgactgat attttatctg gagatacggt agctgtcacc
     7081 ccagaaggaa ggttttctac tcttaggttg acacttactg tacctggata actatgtgtt
     7141 agatccgcca caatcttaaa attacgtgta tcattgttca cttcagaatc taatttgata
     7201 cgattagtgg aggttagata aacttccgca ccataagaat acccactgat aaaatatttg
     7261 tcactatcat acttcatatc aattggtaca tctttaaggc tatgcgtata ggtttcaatc
     7321 gggctataaa tttgcgagct agaattatta tgattgctcg atgctgcagt taaaaaaagg
     7381 agaatcgcaa aaaagactga taccattcct aaccaaggac gactatttaa aaatcgtttc
     7441 atttagattt ccctcctaga attttcttat accatggtaa actaacattt gaatcactca
     7501 tcaggtaggt cctaagtacc gtttcaaatt catctgtgct taaatcgtgt aaaaattggc
     7561 ctttgcgagt tactgaaata gctcctgttt cttctgaaac aatgatagtt agtgcatcag
     7621 agttttcaga taatccaata gccgctctat gacgggtccc aaattctttg gaaattgcct
     7681 ttgattctga caaaggcaag taagcacagg ctgccacaat cttattctga ccaacgataa
     7741 cagctccatc atgaagcggc gtattcggaa taaaaatatt gatgagtagt tgacttgaaa
     7801 tgtcggcatt cagcggaatt cctgtcgcaa tatattcttg taaggtttga gtctgttcaa
     7861 tagcaatcaa tgcacctatc ttgcgtggac ccatataggc cacagattta atcaaagcat
     7921 cgaccaaagc agattcactg ctgacgtact gtttttgtaa aaaaacttgc gtagaacgac
     7981 caaatttctc cagtcctgct cgaatttcag gggtaaaaat gactactcct gcaattacac
     8041 cataagtaat gacttggttc attaagtatg tgattgtcgt aaagccaatc cactctgcaa
     8101 taaaacgaag aaccaaaaag aaaatgaccc cttgaactaa agacatgatt ttagttccag
     8161 tcaatgcttt aataaaacga taaatcaaat aggcaacaat tagaatatct aaaagatgca
     8221 ctgccagcag ccaaggatcc gcaaataagc ttaataaaaa tttaatatcg atactagata
     8281 aattattcat acaactctca tttctatatc aaaaaagtta ttagctatat tatatcatat
     8341 catgatcaaa gatttttccc tatctaaaat caataaactt atgataaaat ataagcatga
     8401 aaatgaagac attactcggc attattgctg gcaaagctgc tcaatccatt ttaacaaaac
     8461 tagggcgagg atctacttat cctggtcgat tggctctagc ttgtaataaa gatattttaa
     8521 aggatttgtc taaagactat gatattgtgg tcgtcactgg tactaatggt aaaacgttaa
     8581 caactgctct tactgtcggt attttgaaag aggcatttgg cgagataatc acaaatccaa
     8641 gtggtgccaa tatgattact ggaattactt ctactttttt agctgctaaa aaagggaaat
     8701 ctggaaggca aattgctgtt ttagaaattg acgaagctag tcttcctaga attaccactt
     8761 acttaaaacc tagtcttttt gtttatacta atatttttag ggatcagatg gaccgctacg
     8821 gagagattta tactacttat cagatgattg tagatggtgc tcgaaatgct ccaaaagcaa
     8881 ctattctagc caatggagat agtcctattt tctcttctaa ggacatagtt aatccagttc
     8941 agtattatgg ttttgatact gctaagcatg ctccgcagct agctcattac aacacagaag
     9001 ggattttatg tccaaaatgc gaacatattc ttcagtatcg tctcaatact tatgcgaatc
     9061 taggagactt tatttgttta aattgtggct tcaagagacc acagttggat tatcgattaa
     9121 ctgaactcac gacgattacc aatcacagtt ctgagtttat cattgatggc caagattaca
     9181 aaatcaatgt cggtggctta tataatattt acaacgccct cgctgccgtc tctgttgctg
     9241 aatttttcgg tgtttctccc gagaaaatca aggcgggctt taacaaaagt aaggcggttt
     9301 ttggaagaca agaaactttt actattggtg ataaatcatg cacccttatc cttatcaaga
     9361 atcctgttgg agccagtcaa gcgcttgaaa tgattcagct agctgattac ccatttagct
     9421 tatctgtgct tttaaatgct aattacgctg acggcattga taccagctgg atttgggatg
     9481 ctaattttga actcatcacc caaatgccca ttacagaaat taatgctggc ggcgtccgcc
     9541 actctgaaat tgctagaaga cttagagtca caggatttga cgatactaaa ataaagcaag
     9601 ctgaaaagct cgagcaaatc atagaaacca ttgaaaaaca agaagctaag catgcctata
     9661 ttttagcaac ctatacggca atgttagaat tccgtagctt acttgctgac cgccatgtcg
     9721 ttgaaaagga gatgatctaa tgacatacac ttcactaaaa tctcccgaaa atcaagatta
     9781 catctacgac ctcactatcg cccatctcta tggtaatctt atgaatactt atggtgataa
     9841 cggcaatatt ttaatgctca agtatgtcgc tgaaaaactt ggagctaggg ttactgttga
     9901 tattgtgtct atcaatgata cctttgaaca agacgattac gatattgttt tctttggtgg
     9961 tggtcaagat tatgaacaaa gcattgttgc caaggatttg cctagcaaaa aagctgcctt
    10021 agcggattac attgctaata ataaagtggt gcttgccatc tgtggtggct tccaattact
    10081 agggcaatac tatgtccaag ctaatggggt taaaattgat ggacttggaa ttatgggaca
    10141 ctacaccctt aatcagcacc aaaatcgctt tattggagat attaaaattc ataatgacga
    10201 atttaacgaa acctattatg gctttgaaaa tcatcaagga cgtaccttct tatctggtga
    10261 cgaaaagcca cttggacgag tggtttatgg caacggtaat aataaagaag accaaactga
    10321 aggtgttcac tataaaaacg tctatggtag ttatttccac ggtcctatct tatcacgcaa
    10381 tgttaatctt gcttaccgct tagtaacaac agctcttaaa aaaaagtatg gatcagctat
    10441 ttcactatct agctatgatg atatactgaa acaagaaatc actgaagaat atgccgacct
    10501 taaaagcaaa gcttccttta ataaagttta agttcttctt tcatgtcatc aaacaaaaac
    10561 tcctaagcag gacacgatat ttcgcttagg agttttatag ttttttcttc tgacagagct
    10621 tcttaagtga ttaaaaccac taagaaacaa tagctttagc aacttcttca acggtcatgc
    10681 gtgagaagta ctgggtcgta tcaatcgttt ttaaacgttc aaaaacatca cggtactcat
    10741 atttacaacc aattaataag ttctcaatgt cttgcacatc tttgattcca aagaaatcac
    10801 catagatttt aaggttttta atgatagaat tttcaacatt tgcaaaggtt gaaattttac
    10861 ctgcagggta acgaacattg cgtccaatcg tatattctgg cgctttgccg taggtccaat
    10921 cccaactacc aaattgctct ttggcagatt gttcaatctt agccaactca tcctctgaca
    10981 agacatattc tgtcatgtct ggatacgttt ctttcatctt ggtcaagatt ttatctgaaa
    11041 attcctcaac ggtaattttt tctggtaatt catttaaaat attggtcacg cgagcacgaa
    11101 cagacttcac tcctttagac tcaatcttat ccttacttac cttaagagca tcgccaagaa
    11161 cggtcatatc cacatcaaac aaaaggcaac catggtgcat catgcgacct ttgtagtaag
    11221 cttgagcatt accacagatt tttttgccat caatttcaat atcattacgg cctgtaaagt
    11281 tggctgttac acccaaatca gctaaagtcg caatcacagg ttgtgagaag gttttgaaat
    11341 caaatgcgcc ttccgctgtt ttatttgaaa tgatagtgta gttcaagtta ttcaaatcat
    11401 gataaaccgc accaccacca gataaacgtc gcacaacatg aataccatgt tcatcaatgt
    11461 attctttatt gatttcttga atggtgtttt gatgtttgcc aataataata gctggctcat
    11521 tgatccaaag gataaacaat tcgtcttctt ccactagttc tctaaaagca taggcttcca
    11581 aagcgatgtt aaaggcagga ttgtgacttt tgttaacgat gtatttcata ggagaaaaaa
    11641 tcctttcaaa aatgtaatct acctctctag tataatgaaa acaaatataa aagacaagtg
    11701 tcctattctg tatgacatct tcagtaccta cacttattag tgcacaaaaa ctcagccatt
    11761 atttatgtaa gggtttataa aaatacttta acgtggtata tttttactta gtaaaccaat
    11821 ctacttttat tatctcattt ttatattgga ggaatgtatc agtgaatact tatttttgca
    11881 cacaccataa acaattacta ctttattcaa acctattcct tagctttgct atgataggcc
    11941 aaggaactgc catttatgcc gatacactga cttcaaattc agaacctaat aatacttact
    12001 ttcaaacgca aacgctcact actacagata gcgaaaaaaa ggtagtacag ccacaacaaa
    12061 aagactacta tactgaattg ttagaccaat ggaacagtat tatcgcaggc aacgatgctt
    12121 atgataaaac caatcctgac atggtcactt ttcataataa agctgaaaag gatgctcaaa
    12181 acattattaa aagctatcaa gggcctgacc acgaaaatag aacttacctt tgggaacatg
    12241 caaaggatta ttccgcttct actaatatca cgaaaactta ccgcaatatt gaaaaaatag
    12301 caaaacagat cactaatcct gaatcatgct attatcaaga tagtaaagct attgctattg
    12361 taaaagacgg tatggccttc atgtatgaac acgcttataa tctagatcgt gaaaatcatc
    12421 aaacaactgg aaaagaaaac aaagaaaatt ggtgggttta tgaaattgga actcctcgtg
    12481 ctattaataa taccttatcc ttgatgtatc cttattttac tcaagaagaa attcttaaat
    12541 acacagctcc aatcgaaaaa tttgtgcctg accctactcg ttttagggtt cgcgccgcca
    12601 atttttcacc ttttgaagcc aatagcggaa atttaattga tatggggcgt gttaaactca
    12661 tttccggtat tcttcgtaaa gatgatctcg aaattagtga tacaatcaaa gcaattgaga
    12721 aagttttcac gctagttgac gaaggaaatg gtttttacca agacggttct ttaattgatc
    12781 acgtggttac taacgctcaa agtccacttt ataaaaaagg cattgcttac actggagctt
    12841 acggtaatgt gcttatagat ggcttatcgc aattaattcc tattattcaa aaaacaaagt
    12901 ctcctataga agcggataaa atggctacta tctatcattg gattaaccat tcttttttcc
    12961 ctatcatcgt tcgtggagaa atgatggata tgactcgagg gcgttctatc agtcgtttta
    13021 atgctcaatc tcatgttgct ggcattgaag cacttcgtgc tattttacgt attgctgaca
    13081 tgtctgaaga gcctcaccgt ttggcactta aaacacgtat aaaaacactc gtcacacaag
    13141 ggaatgcttt ttacaatgtc tatgataatt tgaaaaccta tcacgatatc aaacttatga
    13201 aagaactact aaatgatact tttgttccag tccaaaaact tgatagttac gtagctagtt
    13261 tcaatagtat ggataaattg gcactatata ataataaaca cgattttgct tttggcctat
    13321 caatgttttc gaatcgaact caaaattatg aagctatgaa taatgaaaat cttcatggct
    13381 ggtttacttc tgatggaatg ttttacctat acaataacga tttaggacac tacagtgaaa
    13441 actattgggc aacggtaaat ccctaccgct tacctggaac cacagaaact gagcaaaaac
    13501 cactagaggg aactcctgag aatattaaaa cgaactatca acaagttggc atgactagtc
    13561 tctctgatga cgcttttgtt gcaagtaaaa aacttaataa cacaagtgct ctagctgcta
    13621 tgaccttcac taattggaat aaaagcctca ctctcaataa agggtggttt atcttaggaa
    13681 acaaaataat ctttgttggt agcaatatca aaaaccagtc atctcacaag gcgtatacaa
    13741 ctattgaaca acgaaaagaa aatcaaaagc acccttacca tgcttatgtt aacaatcaac
    13801 ccgttgactt gaataatcag ctagttgatt ttacaaacac taaaagtatt ttccttgaaa
    13861 gtgatgatcc cgctcaaaat attggttact acttcttcaa gccaacaaca cttagcataa
    13921 gtaaggcact tcaaacaggg caatggcaaa acataaaagc tgatgacaaa tcaccagaag
    13981 ccatcaaaga agtttcaaat acctttatca ctatcatgca aaaccatact caagatggcg
    14041 atcgttatgc ctatatgatg cttccaaata tgactcgtca agaatttgaa acctatatta
    14101 gcaagcttga tatcgacttg ttagaaaaca atgacaaact ggccgctgtc tacgatcatg
    14161 atagtcaaca gatgcacgtc attcactatg gaaaaaaagc aacgatgttt tcaaatcata
    14221 atctttctca tcaaggcttt tatagttttc ctcatcctgt caagcaaaat cagcaataaa
    14281 agcttgctca tcaaggaatt gcagctaaaa acaatgctct taactctcat aaaattaccc
    14341 acaaaagaca acgacgctta ccgcatactg ggtatcagtt ctcctcttta gaattcttag
    14401 gtggagcttt agttgcttct tttaaccata tcacaaaacc ctttcgtaag aaagacttaa
    14461 ggatttagct gttattggaa agtaagggtt aacaatgaaa cgttattaaa gacaaaaaac
    14521 tggaaactgc actgagcccc aaaagttggc tactctattt gaagtaaagg atttagttct
    14581 gtattgtaga ggactaagtc cttttcgttt tattttgata cggttattgg tgcaataatc
    14641 gatgataata gtaggtagaa cgagtcactt tagccgtcct taaaagaaaa tctaatcaga
    14701 gctcgtcttt gtccattctt tataatggtt ttttgtcttc ttcttttcag agatgcttct
    14761 ttcaaacgga gttctctcgt ttttttagcg ctaaatgtct agcttatctt catagcttaa
    14821 tgtcatacaa aaacacccca aacgttaggg ttttatatct aacgtttggg gtgcagttca
    14881 tagttgtgct agtctttttt gtgatctgtt atgtgatgat atttttcatt agttaataag
    14941 acaaagacgt tttacttacg ttttggtggg ttatggatag cttcgccaag cacatctgca
    15001 aaggcttcgt acatcacttc agagaaggtt gggtgtccat gaattgataa taacaattca
    15061 tcaacggtta attcagattc cataatagta gctgcttcgt taatcatctc agctgcagct
    15121 ggaccaataa tatgaacacc taagatttcg tggtatttgg catcagcaat aactttaaca
    15181 aaaccatggg cttcatttga agcaatcgca cgtccattac cagtaaagct gtttttacca
    15241 ataagcacat caccatattg ttcacgcgct tgttcttcag ttaaaccaac cattgccact
    15301 tcagggtgtg tgtaaacggc tgctggagtg tatttaaggt tagctttacg agttgtgttg
    15361 ccatgtatcg cattttctgc agccacttca cccatacggt aagcagcgtg agcaagcatt
    15421 ttcgttccgt taacgtcacc tggcgcatag atacctggaa ttgatgtctc ttggtagtca
    15481 ttaactttga tacggttacg atccatttca aggttaagat tttccagacc gttcatttgt
    15541 ggtacacgac cgatagaaag aagagctttt tcagcgacaa cttcttcacc attgttaagt
    15601 ttcaaggtca attggttatt tgcttcaaca atttcagaga caccaacaga tgttttgatc
    15661 ttcatgcctt tcttagaaag gattttttga agttcaagag agacttcctt atccatagct
    15721 gggataatgc ggtcagccat ttcaataacg gtaacatcca caccgtaaga tgcccaaaca
    15781 agtccaagct cgataccaac aacaccaccg cccataactg ctagtgattt tggcatttca
    15841 cggaggtcaa ggatatcgtc agacgttaag acaagtttag agtcaattcc tgggatattg
    15901 atacgtgata ctttagaacc tgtagcaagg ataacgttgc gacccttaat ggtttgtgac
    15961 ccaatggtta cagtcttgtc agggttaact tgaccaagcc cattaaagat agtgacttta
    16021 ttagctttta gaagaccttg aacgccgcct gttaaggttt taacaacggt gtttttaaag
    16081 tcaactgttt tgtccatgtc aatggtatag ttagttgagg caaggttaat cccacgtcct
    16141 gctgcaatct taataccatc aaggatttca gcatttttaa ggtaagtttt ggttgggata
    16201 caccctacgt tcaagcaagt tccaccaaat tcagatttct caacgatggc aattttacca
    16261 ccaagttgag caccacgaat agctgcataa taaccagcag ggccaccacc aacaacgatg
    16321 atgtcatact catcatcagc aagtgcagct tttggtgcag ctgaagcagc ttgagctggt
    16381 gcttttggca cttcaagtcc agcagcttct aaatcttctg ttgtacgagc aacattcaca
    16441 tctgaagcag ctgggctaga aacctcaaca gattcacctt cagcaccgat atatccgata
    16501 acttctgtta caggtactgt ttcacctgct tgacgtgtaa ttttaagaag aacacctgag
    16561 tcttctgctt caagttccat attggtttta tctgacatga tttcaagaag aatatcgcct
    16621 tcattgacag tatcaccttc ttgttttttc cactcgatga tttcaccttc ttgcatgtca
    16681 acaccgagtt ttggcataat aatttcaaca gccataattt aagataccaa gagcaaggag
    16741 aaagcgattg aatttttgcg gtaagtcaga aatctttgat ttcgttgacg cacccacgtc
    16801 aggacgacta ggactttccg aaacaaaaat tgaggaaagt tcagacgtct acgacgctaa
    16861 gattagccaa ctcttaccat ttttatccga gcttttcgct cggattcaat tgcttatcac
    16921 tcatttgcat gagatctcct cgttctacat cctttctata tttttgagaa aagggcaccc
    16981 accaagtcta aacttagcaa aatccctttt attattgaat gcttttcttg tttaaaactg
    17041 attgatcaga ttaacaattc aaatggattt tccatcaatt tcttgagatc aaccatgaat
    17101 tttgcaccgt tcataccatc aactaaacgg tggtcgatgg ttaggcacat cgccataatt
    17161 ggacgggcaa caatctcacc atccacaacc gttggagttg ggatagttgc tccaacacca
    17221 agaattgctg agtttggttg gttaataatt gggttaaatg tcttcgtacc aaacattccc
    17281 aagtttgtga tagagaaggt tgatccagac atttcagctg ccttcaactt accagtttgc
    17341 gcttttttaa tcacatcttt tgaagcaagc acaaaatctg acaagctcat cttgtcagcc
    17401 ccatggataa caggaacgat aagaccatca tcaagaccta cggcaatacc aaggttcaca
    17461 aagcggtgca attcaatatc attagcatca ttgatgaggg aagcattcat gtactcatgc
    17521 tcaagtttca tcaaggtttt aaccactgcc ataccaatca agtctgtaaa gctgacttta
    17581 aggcctgttt tagccatgat tgggtcaatt aacttcttac gaagggcaat catctctgtc
    17641 atgtcaatat cgtagttaag cgtaaaggta ggggcagtaa ggtaagagtt tgtcatacct
    17701 ttagagattg ccttacgcat agctgacatt ggcttgtatt ccacaccttc tggaaggtca
    17761 acaacttttt cttctttagc tgctggggct tttgcttcag ctggtttagc cgcttcaaga
    17821 atagccatga tgtcttcttt catgacctta ccgttaaagc cagtacctga tacggttgcc
    17881 aaatcaatac ctttgtctgc cgcaatttta cgagcaagtg gtgaagcttt cggttgagca
    17941 cctttaaagt tttcaacgtc ttctttatgg acacgtcctt ttggtcctgt tcctggaact
    18001 tggccaaggt caatgcccat ttctgctgct accttacgtg cagctggagt agcacgaact
    18061 tttccaccat ttccttgcgg aatagctgtc gctgccactt gaggagctgg acttgccaca
    18121 ttttcttttg gagcaactgc tggtccagca tctgctgaag caggaactgg aatttctgtt
    18181 gttttttcac ttgaagcaat agtatctact gattcaccct ctgcaccaat gtaaccgata
    18241 acttcagtta caagtacagt atcaccagct ggacggacaa ttttcaatag cacacctgag
    18301 tcttctgcct caagttccat attggttttg tctgacatga tttcaagaag gatatcacct
    18361 tcattgacgg tatcaccttc ttgttttttc cactcgatga tctcgccttc ttgcatgtca
    18421 acgcccagct ttggcataat aatttcaaat gccatttcta catcctttca cgatttgata
    18481 agcgccatca acatccccac cttgttacga aaacatacga aaggtgaggt gccgcgacac
    18541 gggataagac aactcagttc ttctaaaaac ttttaaaata gtttttagct gagacgttac
    18601 tgataaacat agcctttatc agaccacttg ccttatcttc tagttgcctt tgtttgccat
    18661 tttcacaatg gcagctttga ttttctcaac gtctggtaag atcgcttgtt caagtacacg
    18721 tgcataaggt actggaacat cttcacttgc aagacgaacg attggatgat caaggtaatc
    18781 aaaggcttca ctttcggtaa tcatggttgc aatttcccca atgaatccac cggtcttgta
    18841 ggcatcgttg acaagcatca atttacctgt tttcttaaca gattcaataa tcaactcttt
    18901 atcaagtgga atgagggtac gtgggtcaac aacttcaacg ttaataccat ccgctgcaac
    18961 ttcttcagcc gcttgaagaa cacgctccaa catacgaccg tatgacacaa ttgtcaaatc
    19021 agttccttca cgtttgatgt cacctttgcc aagtgggata tagaagtcag gatcttggtt
    19081 aacttcttct tttttaccgt aaagcgcttt tggttccatg aaaagaacaa tgttattatc
    19141 acggatagct gattttaata agcctttagc atcgttggca ttaccaggag caacaacttt
    19201 gattcctgga atgtgagtca accatgcttc aagagattgt gagtgttgcg cagcggaacc
    19261 aataccagaa cctgatgcca cacggaaggt tacaggggta ataaggcctc caccgaacat
    19321 gtaattattt ttagcaccat tattcacgat agcgtccatc atgatggtaa ggaaatccat
    19381 gaaggtaacg tcgacaattg gacgtagtcc tgtaatcgct gcaccaatag ctgcaccaga
    19441 gatagcagct tctgaaattg gggtatcttt aacacgttta ggaccaaatt cttcaatcat
    19501 tccaacagaa gtcccgaagt ctcctccgta aacccctacg tcttctccca taaggaaaat
    19561 gttttcgtcc ttgcgcattt cctcagtcat agcaaggttg actgcttcac gcaaagccat
    19621 taattttgtt tctgacatca tttttacttc tccatttatt attcaaatac gattgcttct
    19681 tactgacaag gtgatcttag tcaacccaaa cgtcttcgaa ggctactgaa agttctggat
    19741 ctggactgtt ttgtgcaaat tcataagcat cgtcaacttc ttttttgact tgtgcttgaa
    19801 tagcatccaa ttcgtcatca gtggcaatgc cttcgcttgt cagataagta cgatatttga
    19861 tcattggatc tttttctttc cactcatcca cttcttcttt agtacggtat ttaccagcat
    19921 ctgcagtcga gtgaccaaac caacggtatg attctacctc aacaatagct ggaccatttc
    19981 caccacgaac atgttcaacg gctttcccca ttgtttcata aacagccatc acgtcattgc
    20041 catcttcaca gtagaaacca ggaattccgt aagcttctgc acgtgtgtat aagtgtggtg
    20101 tatttgttgc attattgatg ctcattgaaa ttccataacg gttgttgatg atgaagaaaa
    20161 taacaggaag tttccatgtt gcagccatat taacagactc gtggaatgat ccttcgttag
    20221 tagcgccatc acctgagaaa gcaacagcta tattgttagt tcctttgtat tgttgagtga
    20281 gggcagcacc aactgcaaga gcgtaaccac caccaacgat accattggta ccatagtttc
    20341 ctttttcaaa atcagccaag tgcattgagc caccacgccc tttagacaca ccagttgctt
    20401 taccagcaag ctcagccatc attttattaa ggtccatgtc tttagcgatt gattgtccat
    20461 gtccacggtg atttgaaaaa ataatgtcat cgtaagacaa gtgagccacc gctccaacat
    20521 tggctgcttc ttcaccaact gagaagtgag tcatcccttg tacaaatcca cgacggacga
    20581 gtttattaat acgtgaatca aattcacgaa tacgttccat tttaaggaac atatccaaat
    20641 gttgttcttt agaaactgtt accatttcgg cctccatatt atcatattac ctttttatga
    20701 taaaactttt tttcacaatt tgcaaataat taaatcgctt tctaccttac cttatttggt
    20761 tttttagaaa tgcaatagtt tgtgaaatta caaacaaaac tgtactaaaa aatttaaaaa
    20821 tactatataa cagtttcacg ttttaccgac cttgacataa aaaacatatc attttaaaac
    20881 ctctttcaca ccttcaaaca agtagcaaag cgataaaaat aagcttagca aaactgctaa
    20941 agcttatttt tatgattcta tttgttcagc gatggtttcc cattcttcca taagagtttc
    21001 ttgttcttga tccaattggt cccattcctt ttgccaagcg attaactgcg ccgtatcatt
    21061 ggaggcatgc atgtcttctt gaatagcacc aatgcgctct tcaatggttt caagtcttgc
    21121 ttcaatctcc tcatatcggc gggtcaagcg acgacgctct ttttgattag ctttttgtag
    21181 ctgataatca gtggcagagg cttcttttgt ttcctcaact gtctctcctg ctgctaggcg
    21241 ggctagttct tctagctctg cctttttctc aaggtaataa tcatagtcac ctaagtaaag
    21301 ggttgagcca ttttcggtaa tttccagaac cttagttgcc aaacgattaa tgaaatagcg
    21361 gtcgtggctg acaaaaagca aggtgccgtc aaagtcaatg agggcattct ctagcacttc
    21421 tttactgtca atgtctaggt ggttagtcgg ctcgtccaga acaagaaaat tattgttttc
    21481 catagataac ttcgcaagaa gcagacgggc tttttctcca cctgacagca tggccaccga
    21541 ttttttgaca tcatctccag aaaagagaaa ggctcctaat cggtttctga tatcaacttc
    21601 tggcgtggtt gaaaaatcct gccataattc ttccaaaact gtgttgctag acgtcaaatg
    21661 tgattgggtt tggtcatagt aacctgtttc aacattggca ccgtatttca cttctccttt
    21721 gatgaaagga atctgtccaa taacagattt aatcagagtg gatttaccaa taccatttgg
    21781 accaacaata gcaatcgcat ctaatttgtg aacgtctagg ttaataggtt cagataagac
    21841 atgttggtta taaccaatag cagctttttc aaccgtcaac accacattgc cagacggctt
    21901 atctgcctga aaagtcatgt gagctgattt tctagcacta gtcggtttgt ctaagcgttc
    21961 tattttttcc aattgcttac gtctcgcctg agcacgtttt gtagttgaag ccctgacaat
    22021 atttttttga acaaaatctt ctaacttggc aatttctttt tgctgtttgt caaactgctt
    22081 ttcttcggct actaattttt cagcttttaa ggtcagaaaa cgagaataat tgccaacgta
    22141 gcgatccaag ccatgaggag ttaaatccaa ggtcactgtt gccaccttat ccaaaaaata
    22201 acggtcgtga ctcacaatga ttagagctcc ttgataattg gccaagtagt tctctaacca
    22261 ggcaatggtt tcaatatcta agtggtttgt tggctcatca aggaccaata gttctggctt
    22321 ttctaaaagc attttagcca aggccagacg agtgttttga ccccctgaca gctcagcgat
    22381 agtcatctgc cacatgctct catcaaactt aaacccattt aaaatggctt tgatgtcaga
    22441 ttcatacgta aagccgcctt gctgacgaaa atgctctgta agcagatcat aatctgtcat
    22501 cagtcgggtt aaatcttgac ctgaaacggt tgccatatcc atttccatct gacgcaggcg
    22561 cttttcatct tggcgtaatg cttcgaaaac cttgagcatt tcctcatata ttgtttgatc
    22621 tgattcaaaa cggctatttt gagccagata agacaaggtt aggtcttttt tagtattaac
    22681 ttctccgctc gttggggttt cttccccaac caatagcttg agtaaggttg acttaccagc
    22741 tccatttggc cccactaatg caattctgtc tctttcatca acttgcagtg atatgttttg
    22801 aaaaagaaca tctcctgaga aagagcgttc taacttgttt ccttgtaaaa taatcatact
    22861 ttcattctaa caaaaaaatg cccttttgag gacattttca gcctagtttc caaaagaaat
    22921 cgaactcttt ttaagtcgtt gattaccttc tttagcgcta acaaggaaag tggaatgact
    22981 attaccactc ccatgacgcg tctttgcaga tggcttttgt gttaagatat caaaaatttg
    23041 caccacttgc tcagtaacta tcgagatctt attggctaaa acggaatcac tgtgattaga
    23101 atagtacatc agccctataa taataatcgt tactaataag atagtttgta aaaacccttt
    23161 gataagatgc caaaacattt tcactattag cttaggcagc cacaatatga tcgccagtaa
    23221 ttgtttcatt tgtcacctca tgttgtacta ggaaatggtt aagacaacct ttcttctttt
    23281 tggtagttta tcggtaacca ctctaacagg acttctaatt gctggttcca atagtaccac
    23341 tcatgtttac catgaccttt atgataatca atgtcaagac cttgagcctg aaaatcagca
    23401 atggcttttt cattagtggc aaaaagaaaa tcctcatagc cacaccaagc ataaaatttg
    23461 gtttttccat cactttctgc caccatattt ttaaggtaat gcttatcaag atcaggatca
    23521 tcaaactggc caaaaacgcc ctgccaatag gctaattctc ccaggtttcc ctcaagcaag
    23581 gtctcaggag aaaaatccaa agcgcctgaa aacgatgccg cataagaaaa ccgattgctt
    23641 ttgagtgccc acttaaaggc accatagcca cccatagaga gcccagcaac aaaggttttt
    23701 tctcgtttct gggtcatatt aggaaagaaa gctgctaaga cctgcggtaa ctcttgtgac
    23761 aacgcccgat aatagttaag tccataagcc gtgtctgtat accaacctag gtctgtcgaa
    23821 ggcataacga ctatcaaatt ggtatgccgc aacaagcgtt caatagctgc tcgtttttgc
    23881 caagagtttt cattgcctcc cataccatgt aacaaatata aaacaggaat atccttatcc
    23941 ccttgatctt ttttagggat ttcagactgg tcaggataaa tcacatttac cttacgctcc
    24001 attcctaaaa ctaccgaatg gtattcaatt gcaatatttg ccattcatta cactccttta
    24061 taccaaaata atcctatcac gtaaatctac tgtatttttg ggtgaacagt ttcctggttt
    24121 accagttgtt aaaatcaaag aaggtaggca gtttttgcct aaccttccta ttttcactaa
    24181 cgaacttcca tcacaaccgg cagaatcgct gggcgccttt tggtttgttc aaataagaat
    24241 ttagacaaat catctctgac attccctttt aattcgcccc agtcaaaggt atcttttttt
    24301 aagtaattgc caacagttgt attaactaat tctgcacttt ctcttaaaat atcatgactt
    24361 ttcttgacat acacaaatcc acgcgtatta actttagcct tagaaataat gcgtttttct
    24421 tttttagaaa cagtaatagc aacaatgaaa ataccatctt ctgacaagac tttacggtct
    24481 cgtaagacga tattacccac atcaccgata gcattaccgt caatcatgac atcactggca
    24541 ggtacacctc cttcatggag aaaaccttcg tcattaagca ccatgatatc gccacgcttc
    24601 agaatatgaa tattctctgg aaaaatacca acttcttcag ctagctttgc atgggcagct
    24661 aaatcacgat attctccttg tactggaaaa agatactggg gttttaacaa attcatcaat
    24721 agttgcaaat cacgcccatt agcatggcct gacacgcgta agttttgagt gattaattta
    24781 acagaaccac cggccttgta aatcaagttt tcaacacgcg ccaccatagc ttctttagcc
    24841 gtacttggtg ttgttacaat ataaacaagg tctccttctt tgatttgaac ataacggtga
    24901 cgtcccgctg ccattttttg taagctatta attggctcac ccatacgacc agcttcaagg
    24961 atgattaatt catggtcttc gaatttagac atatccttag gtttaattaa aagacgctca
    25021 tccgtaatca ttaatttttc tagacgtaaa gctgttctga caatgttttc tgcatctgtt
    25081 ccggttaaaa caacacgacg cccatgggct gtggcggaat caaatacttg ctgaatccga
    25141 acaagatttg aggctactgc agctacaatg acacggccat cagcatcaga gataacactg
    25201 tccatttctt caccaacttc agattcgctg gcaatctgat cgttgcttgt cgcattgact
    25261 gaatctgata aaagagctag aaccccttct ttcccaatct cagctaaacg taacaaatcc
    25321 gtctgataac cttctcttgc tgcttgatca aatttgaagt caccggtata aacaatattt
    25381 cctttatctg ttccaataac aatacccata ctttctggga ttgaatgcgt tgttctaaag
    25441 aacgaaacta gcccatcttt aaattcaatt tcagtatcac tgtctaccac atgaaaatta
    25501 ttaaatttct tagtgctgtt attacttttc acaaatagct tagctaattc aatagtcaat
    25561 tcagatccaa atacaggagc tgatacttca gctaacaaat aaggaagggc tccaatggcg
    25621 tcagcatggc catgactcaa gaaaatccct tgtactttac ctttgttttc aattacataa
    25681 tctaaattgg ggatgactaa atctacccca agttgctcat tttcggggta cttgagccct
    25741 gcgtctaaaa taaacataga atcgttaatt tctaccaaat agaagttttt tccgtattca
    25801 cggacccctc ccaaggcaat cattttaata tcagtcatga tactccttta aatattttat
    25861 tattacaaac ggtccttaca acgtaagtcg aattactgtt atgtagctat gctactatct
    25921 tctatagtat atcatatttg aggcgttttt tctctaaata gccttgatac tttcagatta
    25981 ttttcagtac agaaatcaaa aaatcactga cttattatta gtcaatgatt tagatcgttg
    26041 actaatcaaa tagttggtaa tagtcagtaa tcgtcagttg ttctttttcc atttgattta
    26101 aatctttaat aatgtttcca tctttcatta caatcagacg attcccataa gttaatgcat
    26161 cttccatatg gtgggtaatc atcaaagctg ttaagccatc ttttgtcaca aactcatctg
    26221 tcagttgcat taaagattga ctcgtcttag ggtcaagggc agccgtatgc tcatctaata
    26281 ataagagagc tggctttttc aacgttgcca ttaataaact taaagcctgt ctttgtccac
    26341 cagacaaaag acctgctggt gtttctaaat gcttttctag gccatttcct gttcgtttaa
    26401 ccaaatcctc aaaactagct aagtgctctg ttatttttcg agaagccaag gagcgttttt
    26461 ctcctctttg acgtgcgatt aagagatttt cagccactgt catccgaggg gctgttccca
    26521 ttttgggatc ttgaaagact cgcgataggt aaagagctct tttttctgcc ggccaatgcg
    26581 tcacatcctg accaagaatc ctaatttgcc cccgtgtcaa acttagcgtt cctgcaatta
    26641 cattaaaaag ggttgatttt ccagctccat ttcctcctaa aatagttaaa aaatcatgtt
    26701 catagatagt tagtgtcaca ttgtccaata ttgttttagc atcttcaaaa ccattatcta
    26761 cgtcaactgt tgcattgatc aattcaataa tttttgtcat cgtgttaacc tcactccctt
    26821 aaagaagcgc tcttttacca ctggtatcat gaggcacagt gctaaaacaa gagcactaat
    26881 taatttcaaa taacttgtat taaaacctag cgtaataact actgaaatta aaaattgata
    26941 aagaatcgag cctattacaa tagcaatcaa acgttctaaa agagtcagtc cagttgagta
    27001 tagtacttca ccaacaatta tgctcgccaa accaataaca ataactccaa tcccttttga
    27061 gacatctgca tagccatctt gttgactcac tagagcacct gataaagcta ttaaactatt
    27121 agaaaccaca agtcccataa cttccatcca atccgtgtta ataccaaaac tcttagccat
    27181 atctttattg tctcccgtag caatataagc ttgacctaga ttagtgtaaa ggaaatagat
    27241 caaaacgcta ataacaatca caacagttat cagacctgtt aaaaggctat ttaaatcaat
    27301 tgaaaaaggg aaacaatcct gaatacgttt atgatcatgt aaacccaagt ttgctcttcc
    27361 cattaccatt agcataatgg agttacatga cgtcatcacc aaaattccag ctaaaagtgt
    27421 tggcattttt cctttcgtat ataacagccc tgttagaaaa cctgctaaag cacctgataa
    27481 cataccaagt aaggttgata gaaatggatt ccaccctaag ctaatagcgg tgaccgcaac
    27541 agctcctcct aaaggaaaag aaccttctgt agtcatgtca gggaagttta aaatcctaaa
    27601 ggtcaggtag attcctaatc ctaaaactcc ccatataagg ccttgtgaaa ctgatgaaat
    27661 aatcatattt ttcctcatat ttatattagc gggtaacgct cgccagtata aaccctttct
    27721 ttacattaat ttttagattt gttttatact tagttcagca ccgtggctta gtcttttttt
    27781 tcaatcactt tgacgaaact aagacagaaa acaaaaaagt cgagaatcat gtttaaactt
    27841 actcaaaagg caagattttt tacgtgtcta aaatagagca ttttaaaact aaaaatgata
    27901 aaaataacca ttacatcctc aagacgattg tctgacttgg catccaaatt cacctcagtg
    27961 agggtgtttt ttatggtttt ttcttgacct tttatatcac atgtctttgt attaattctc
    28021 aataaaagaa gctgaaggaa aatcttccct gttaatagca atacctaatt ctgctgctac
    28081 attcttatta attagcggtt gaccaatatc cacaactttg acaggaacat ctacaacacg
    28141 ctttcctttg attaatttta acacctgatt agctgtttga actcccaaat cgtactgatt
    28201 ttgagaaata gctgccaaac cacctttttc aaccattcga tcaacgctag tgtagacagg
    28261 aatctttgca gccttactgg ttgtcatgac tgatgaaaat gcacttgcta tagtattgtc
    28321 ttgggggata aataccgcgt ctactttacc taacataact gacatcgtgg caggaacttc
    28381 gttagtagaa ggaaccgcgt atgaaataac ttgatagccc tttttgcgag ctaaccgcct
    28441 aaactcttta acttgagata aggaattatc ctcattactt gcatataaaa ttccaactgt
    28501 tttgacatgt ggtgtcagct ttttcattaa atcaattgtc tgtttaacag gcactttatt
    28561 agatagacca gttacattag cttcaggttg atccaattgc atcactaatc tagatcctac
    28621 tggatcagat actgctgaca tgacaactgg gatatccttg ctggcagctg ctaagccttg
    28681 cgccgccggg gttgcgatac caatcacgat atcacttcct gattgcacta attgcctact
    28741 cattgtttgg attttactct gatccccctc agcattcata accttaatca ctacattttg
    28801 tttttgaggc ttctgctttt tgagttgatc ttcaatacct cgcttaatat catcaagagc
    28861 ctcatgagta accaattgta agatgccaat tgtaatgttt tgttggttag ccaaatcacg
    28921 gttttccttt gatactcctt ttgataatag agagcctatc actattacag ttaaaacaag
    28981 gagggtagct attaaactct tgtttttcat ctgaattcct cacatttcat gtcaatctct
    29041 ttaaaacgtt gatgatgaga atacttctca aaagaaaaag cacttagtaa tgattactag
    29101 acgctcttgt gaaatccaat gtcagcgcat agatatcttt ttagaagtac tctaaaagtc
    29161 gtatctatgc caattcataa acacaactta tctatgccag ctttgccaat ttgctaagtg
    29221 ttgtgttttt accatcattg acttcctttc tcgttttttt aacattataa cctaaatcaa
    29281 aaaaattgca agctctttcg tccatatttt tagtcaagta tttgtggtat aatgaagaga
    29341 ttagaattca gaaaggagaa accatgtctt ttgacggctt tttcttacac catttaacca
    29401 acgaattaaa agagaacttg ctttacggtc gtatccaaaa ggtcaatcaa ccctttgaac
    29461 gggaacttgt cttaaccatt cgtaaccatc gcaagaatta taaattgcta ttgtctgccc
    29521 atcctgtttt tggacgactt caaattaccc aagcagactt tcaaaatcct caggtaccta
    29581 atacctttac catgattatg cgtaaatacc tccagggtgc agtcattgag cagttagaac
    29641 agattgataa tgaccgcatt atcgaaatca aggtatctaa taaaaatgaa atcggagatg
    29701 ctattcaggc aaccctaatc attgaaatca tggggaagca cagcaatatc atcttggtgg
    29761 accgtgcaga aaataaaatc atcgaatcca ttaaacatgt tggcttttca caaaactctt
    29821 accgcaccat tttacctggc tctacctaca ttgagccccc taaaacagct gctgttaatc
    29881 cttttacaat tacagatgtt cctctatttg aaatcctcca aacacaagaa ctaacagtta
    29941 aaagattgca acagcatttt caaggcttag ggcgagacac cgcaaaagag ttggccgagc
    30001 ttctgaccac agacaaatta aaacggttcc gtgagttttt tgctagacct actcaggcaa
    30061 atctgaccac agcttctttt gcgcctgttc ttttctcaga tagccatgcg acgtttgaga
    30121 ctttgtctga catgcttgac cacttttatc aagacaaggc tgagcgcgac cgtatcaatc
    30181 agcaagccag tgatttgatt caccgtgtgc aaactgaact ggacaaaaat cgcaacaaac
    30241 taagtaaaca agaagctgaa cttttggcta cggaaaatgc tgaattattc cgtcaaaaag
    30301 gagaattatt gaccacctac ctcagtctgg tcccaaacaa ccaagactct gtgattttag
    30361 acaattatta tacaggggaa aaaattgaga ttgccttaga caaggctctg acaccaaatc
    30421 aaaatgctca acgttatttt aaaaaatacc aaaagctaaa agaagctgtc aaacacttat
    30481 ctggactgat tgccgatacc aagcaaagta ttacttactt tgagagcgtg gactacaatt
    30541 tatctcaagc aagtatcgac gacatcgaag atattcgcga agaattatat caggctggct
    30601 ttttgaaaag tcgccaaaga gacaaacgcc ataaacgtaa aaagcctgag cagtacctgg
    30661 cttcagatgg aaaaaccatt ctcatggtgg gacgcaataa cttgcaaaat gaagaactca
    30721 cctttaaaat ggctaaaaaa ggagaactct ggttccatgc taaggatatc cctggaagtc
    30781 atgtcatcat caaagacaat cttgacccaa gtgacgaggt taaaactgat gctgccgaac
    30841 tagctgctta ttattcgaaa gctaggttat caaatctcgt tcaggtcgat atgattgaag
    30901 ctaaaaaatt acacaaacct agtggcgcca agccaggatt tgtgacttat actggtcaaa
    30961 aaaccttacg ggttactcct gaccaagcca aaattctctc tatgaaatta ttctgataag
    31021 caactaaaaa acagctctcc taggaaagtt atttccccta ggagaactgt ttttttattc
    31081 tgattgttga tgcttgatat ggtcaagaaa gtcttgcata ttcacatcat caggtacttg
    31141 tctgaggtaa gcggtagcca tttggatagc cttgtgaaac tggccaaact cccttaataa
    31201 ataggcataa tcctgtaaaa actctggatt ttctgccaaa tcagccgaaa tctcattata
    31261 aagagccaag gcaacttctt cttgttccaa ggcgtggtaa gcctttgcaa tggtccattt
    31321 ggttaagaca ctatcaatcg tctcacgatt aagagcaata acctcctcaa aacgctcggc
    31381 atcaaaataa agggtcacta aacgcatgag aatctcttcg tcatcaacag ctacttcctt
    31441 tgcttgaagc aggtaatttt cagcattctg cctatcgtgt aattcataag aaagctgcga
    31501 tgctagtaat aataattgac tgtcaaatgc atttttacgt aggccctgtt gaaccaagcg
    31561 caaagcttct gacgtcttat gctcttcatg aagactcaaa gcataaccat attcataacc
    31621 tggataatct ggattgatgg tttccaactg tttaaagtaa agattggctt tttgataatt
    31681 ttcttggtca tacatgaggg tcgccaattc aaaaacagtt tcatcttcgt attcaatggc
    31741 cacggccttt tccaagaatt cgatggctgc ctcaaatttc cctaagctag cataggctcg
    31801 tccaatgcgt tgataagtgg aaatacctgt caattcaagg atttgacgat tgtctaactg
    31861 tgcatagtaa tcaatagctt ctttaaaata ctgcaaggac atgtcgattt ctgccaaacc
    31921 aaaaatgacc agtggctctg agctgatggc cactgcttga agcaattttt cacgcgccac
    31981 ctctgtcagt ccttccaggt catagaggtc agccatgact aagagagctg acaaataatt
    32041 agggctatct tttgaaacct tatccaaata caagaaagct tcttcaatgg cgtcgtcttc
    32101 tgctgcaatc tgagctaaat ttatattgag ttctgggtaa tcatcagcta actgcaaata
    32161 aatacgcttg gcatgtggca aaaaacctat actttctaag tattctccta aggcgattaa
    32221 actatctgca tcatcttctt ttaaagcttt ttggaaatat ttttcagcgt gcgctaggtc
    32281 ttgctgatcc aaggaagcaa tcattttttc actatttaac atggtcctta acctcctcaa
    32341 tcaccaatac ttcttcgtca tacaaaccgc taactttttt gtaccagtca aataattctt
    32401 taatcacaac tttgacagaa gcgtagattg gaatgacaag gaaaacaccc cagacaccaa
    32461 acatagagcc tgcagtcaat aacaagaaca taatggtaat aggatgaatg ctcagcttat
    32521 ttcccaaaac aagcggtgct acaaaacgcc cttcgatggt ttgctcaatc ataaagataa
    32581 caagcacctt aaccaacata aatgggcctt gtaccatagc cataatcaca acaggtatca
    32641 tggcaaggaa acttcctaag taaggtatca tgttaagaaa gccagcaata atcccaaaag
    32701 tgatggcata tttcagtccc acaaggctaa acatgataga aaacataaag ccgacaacaa
    32761 ttgcaaccgt aacctgccct tggacatagc ctgataattg cttgttaata tctcccaaga
    32821 ctcgaaccat aggcacccgt aatttgagag gtaagacatt cacaaggcca tttttcatgt
    32881 ggctactgtc tcgtaaaaaa taaaagagaa taaagggcga aataataata gccacggtaa
    32941 tccgagcaat ggcaccagca aaattaccag cccagtcaat agcatttttt gaaaaacttt
    33001 gcgcgtaatc taaagccttt tgacttgtat gggtaagcat gtcttggagt tggggcttgt
    33061 agctgactaa ccattcattt tcaagaagtt tattggcttc ttcattgacc ttgcccacgt
    33121 atttgggcag atcctcaata aaactggtaa gttgggtctg taccatggga acaaagcctg
    33181 aaatcgccca gacaaaaagt aaggtaatca aaccaaaaac aataaaaata gaggtggtac
    33241 gattcgggcc caagtgatta ataaggtcaa ctaagggttt ggtcagataa tacagaatgg
    33301 tcgaaataac caagggcaac atgatgaccg caaaaaaaga aatcactggc ataaataaaa
    33361 aagagatctt agtaaaaaca aaaatcgtta aaaaggctaa aagtgttatt actaaagcca
    33421 tggtagcttg attatttaaa aaccatttgt aaaataagct atctgttcta gacttttcag
    33481 gtattaagga cattaagata gggttccttt ctttgagaaa atgataagtt ttactggtaa
    33541 cctgggtaaa tcaataaaag gtcacagatt tatccatgag ttggttgttt tggtcatagg
    33601 taaatttggc agagaaaaaa ggacggtctt ctaaaatcca tttaaaaatg tcataatcac
    33661 cttcccaagt tggcttttcc aacacttgat cgtaaggtac ccattccaag gttccttctc
    33721 gtgactcttc atcggaaatg aggtctcctt caaatcctgt tactttaaaa acataggtat
    33781 accagtcatg accaggggta aattctggaa aagtaatgat tcctttaaag gccatctctg
    33841 taacagtcaa atgggtttcc tctaaaatct cacgacgggc acactcatct ggggtctcac
    33901 cagcctcgag cttaccccca actgaaatcc acttgccttt gtggacatca ttttcttttt
    33961 tattgcggtg taataatagc aaagaatcgc cattatcaat gtaacaaatg gttgctaatt
    34021 gagtcatcta tctctttcct ttccatcttt gtttctatta taccaatctc tagaaaatat
    34081 gctatcattt tatgagtcaa agtgtgaata cttagtcacg ctcaaaacct tctaaagatg
    34141 ccttaaaaaa gtgtagataa gagcctacaa tgaaaaacat caatttaaac tatcaaaaga
    34201 accttgtcat atcaacgata attgatatga caaggctctt taatgtttta tttaatcact
    34261 tcttgagttt attcccgaaa aaacacaagg aacaataatg gttacaaagt cgataataaa
    34321 agcatttgtt agtattaaac cggtattgta tcgacacaag aaacgacaaa agttctaaac
    34381 ttatgcccca attttgcccc aatggttctt ttttgattct ttggtgaact aaaattattc
    34441 agactcagaa agttctgcca taacatctga tatccgctcg attgtcacaa cctcccaatc
    34501 tcttatctcc tcatatattt tatattaaaa tatcaataaa tattagcata attttaaaac
    34561 actaaaaata tatcttggta atttttactt tatttatcta tttttaataa acagcttctt
    34621 aaaaatataa ttagctgatt gacacatcta catgaaattg agttgagtct attctctcgt
    34681 tattggaata tatttttagc atgctattaa agtctccatt gccaaaataa tacaaatcaa
    34741 aaacaatatc tttacctgaa tttaaatcta aggtaacagt tcctttagag tatttttgtt
    34801 cccggttatt atagatatcg tatttcttaa tcaataactt tctaactttt atatccactt
    34861 cctgagcggt tactttcggt ttattgactg taataaacat aggcggctgt tgtttacttt
    34921 tatcccacac gtttacagga actttaattt cttttttttc tgaattagtt aatgtaattc
    34981 caccaaacgc ttcatacctt ttccctggac attcacaaac ctcttgtgca gatagagcat
    35041 aaatatctac ttctttatct ttgaattcct gtgatatcca atctttctca aaaaaaactg
    35101 acaaattttt atccttgaca ctatatttca acatatggct tgttacaata tctggagaat
    35161 tttttatact atcggcttca atcaagttag aatcatgctt ataaagcgat tctagattat
    35221 gtctattggt tgtattataa gaatttgctt gaacaacatt ggaatataaa agaaatgaca
    35281 aacatataat catgctgtag attttcttat caatatgtga gtagcgacaa ttatatctca
    35341 ttttttctcc ttaagaagtg agagttttat ttattaaatt taactaagta tatatcaata
    35401 tgaagttgat cagaataagc ggtcttatta tcactgtatt tttttagcat actctctctg
    35461 tcaccatgtc ctgtatcaaa aagattataa gaaattctct ctccactatt caaatgaaaa
    35521 ataatatttc cttcctcaaa gccagattga aatctagagg agcggccaaa atctttaaca
    35581 tcaccgaatc cgtatatatt aaaatgtttt tgaagataat atcttgattt cacatcaagt
    35641 tcctgaatcg taacctcttt cttatcagta ctcactgtac ttatatctgt atagctatat
    35701 ttttgttgaa cgccgtctat gaaaatatta acaggtatat tttttttatc aattctatta
    35761 ccgtcgctta aagtaatacc tccatatgaa ttctttttta tattagagtt acagggagga
    35821 gaatactcca aagtaaatat atccaccctt ttaccagaaa aaaaattagc tttttctacg
    35881 ctattaagtt ctacttttaa ttcaatcgaa ctattgccat aaggaatatt tttgtagaac
    35941 aaactacctg aaaatggcgg accttcattt atttttcctt ttacttctgt tggatcatat
    36001 gtagagtata aattccttaa attaataact cccacactac tcatctcata cgcgtaacac
    36061 gttggaatta tagctgatat aaatacccac aatagaaaag atgaagttaa aaacttttta
    36121 aaattaacat ttacaatttt tctcacttat aagtgtaccc tattcttctt taataataag
    36181 aaatcacaaa atattttagc acaaaaaaga aaaaaatcaa cgaaaatgct taaataacaa
    36241 ttaaaatctt tataacaaaa acagcccccg caaaagcgag ggcatttgtc ttatctaaag
    36301 gagctttacc tcctatttta tacttgtgtt gcattagata aatacttatc ttcgacccac
    36361 tggtcagact gagaagcgtt aatacgtgac catccattca ctttttcata gactcttaca
    36421 cgagttcctg ccttgataaa ttctttatca gcgctacttg cgtttggctt agactctaca
    36481 taatagtctg ttctaagggt tgcttcgtag taaggtacat tcgagttgtc taatttagtg
    36541 ttagtatcta gcttttgatt aaaagtaagc tggctttgtg gtttgtcaat cttaggtata
    36601 tccactttgc tactatcatc tgctaataat acaatatttt tatctaaacc acctgctact
    36661 cctacacttg tgaactgcca ccagcgcaca ccatccattg aagggaagaa ctcccaaagt
    36721 ggctctgttc gtacttcgta gtctggataa ccagctatcc aaatgctgtt tgggtactta
    36781 gcgataattt gctgataatc aatattatta agcgtaaatg gtttatagct gtaataaaca
    36841 ggcttatatc cagcgtttgc aattttatcc ataaacgcaa taactgcatt agtgttagct
    36901 tctttgtcgg cacttgcaga gtcttcataa tcaatgacta agtaagagac ttttttggtt
    36961 ggtaaattgg acagaaataa atctgcttct cgttgcgcta agttgctatc tcctccaaat
    37021 cgtccaaagt gataataacc aatagggtca ctagtattag cttgttgctg atgcctatca
    37081 gacagccaag cgagtgactc ggatactttg ataatcgttt tagtagtgcc agcttgctga
    37141 caagtagcgg ttaagtctgc ttgttgataa gctgatacat caataaaata atcgccttta
    37201 tttagtccta tattacctat aacagtaact gcatttttaa aaacttttgg tctaaatgca
    37261 gtaggataag tcgttgaata tggtattttt actaaattat atgctccgtt tgctccaccc
    37321 tggttttgac ctaaaaacca tccgtatcca ctacctgcat cactatcaaa aatagccaca
    37381 tggctatacg gtgtaacacc tgcaactacc ataaaaattg cgacatctcc agcttgcata
    37441 gtctctactt cgtcaaagta gtttaaaata ccatttttgt gacgttgttc ccatatatcc
    37501 cttgcatatc ctgtatttgt acagtttgcg tatggcagtc ctagatactt acagtagtct
    37561 gcgtagccat cccaacattg cgcaccaagc gatccatcaa tatcgtaagc attgccattt
    37621 gaacgacttt tatattcctg atatgtagcc atttatccct ccttatctaa aaatggataa
    37681 aaaatcaaag caaccacaga taatggcaca tacagtattg cgattgctat aactaatgct
    37741 aatcgtgtga ttgctcgcat gacctattcc tcttccttga tttgtgacac attcatcagg
    37801 atacatgtta gtcctgacaa cagcactgct gacaacattg ttggccaatt aatatccgtg
    37861 attaacacgc ttgacccgat tagaccaacg gccgtttgtg ccattgtttt aattgtttta
    37921 attgctactt ttttaaacca gttattcatt tttcttctcc ttttttaaat agcgtaataa
    37981 tacgctcctt gttgataata acttcgtctt ctacgcgacc taaacgctcc tcgtgtctgt
    38041 cgataatttt tttggtaatc tcacgttcac gatcaagatt tttaagctca taagctaact
    38101 ccttaattga gtccttgagt tgagccatgg caaactcatt agcttccatg gcttttttaa
    38161 agggattgac gataaatccc caaacaccca agatagacaa agcagcgcca caaaaagcac
    38221 caatttgtac aaaatctatc atctaaccac ctcaatcctg cttaactaag tctgcatatt
    38281 tgataactgt tactttgtct tctgactcta gctcctctaa ggtttgtttg tcataagtaa
    38341 atggctcgtt aacgtgtaca aagacaagat taccttctcc tgcctgctct tcgtgcgact
    38401 cgtctactac cgtaaagaca tcataggctt gatactcacc ttttttggct ggctcgatta
    38461 gctctaaaag acctttgtaa atatcaggat caatcttgcc gccgctcgtt aacatgtgga
    38521 tcgtttgtaa gttaatcatc ttttgcgtgc gctctgcgga caccttagct agtccagcag
    38581 ctgtttgagc agttttggca gtcttagcgg tttcctgtga gattttttca aggtcgtcta
    38641 ccttttgcac ggcttcgccc attgcaattt caacgtattc agatttttta aattcttcca
    38701 aagtagcttt gataatctct gtgtcattag tcgagattaa gtcttgctta acaagttgag
    38761 agatgactga gccatcctca gtagtgataa taatatgtgt gcttgcgact gctcctgtgc
    38821 tgtcaaattg tgggtatttt cctgtcactt tccaatttct catggttatt ctcctttgct
    38881 tccttcgtat tgctctaaga tgctgtcaac aataatgatt tcttgagctg taaactcatc
    38941 ttcagattcg gctaaatatt ccaaaaaatc gataaatcgc ttggagtact cacccccttt
    39001 aatcacaatt tcttcatcag ctagctcgtt gagtaggtcg ttgagctcgt cgagtttagc
    39061 ggggtctgct agcttgatgt ttttgtgctc atcaatgaca aatttgtcat ctttatcctt
    39121 agctgcatac atatcaatta agtcggtctc atcttttgca tactcattga ttttatcgac
    39181 tacttttgcg agtagcttag cacgtccgcg gtttgctcgc atgttcgtga ctttgatttt
    39241 gtctagtaca ctatatagtg tgtttaaatc tttgttttta agcgttaaat ccattgtttc
    39301 tcctataagt tattaat
//
LOCUS       DAUCXI010000017        35718 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.017, whole genome shotgun sequence.
ACCESSION   DAUCXI010000017 DAUCXI010000000
VERSION     DAUCXI010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35718
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.017"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(179..2977)
                     /gene="ppc"
                     /locus_tag="VGY43_000871"
     CDS             complement(179..2977)
                     /gene="ppc"
                     /locus_tag="VGY43_000871"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEQ4302070.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQTIIAEEVALLKEMLENITRR
                     MIGDDAFTVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINHQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQIQLTNQPAARMNSSVGLNTSAWPSPASLEKPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNTIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     SNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEW
                     QLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            3136..4935
                     /gene="pepF"
                     /locus_tag="VGY43_000872"
     CDS             3136..4935
                     /gene="pepF"
                     /locus_tag="VGY43_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ4302071.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEEALQDIDLFKRN
                     YEDRLTSVDDFTQALIEIEHIYTQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRAGDFDMDDFEVDGKTYKNSFVSYENFYQNHENAEIRDKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYTSVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNDLNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVMSTAGYLNLKNNPDGAKEWLDFLKSGGSRTPLDTAMLIG
                     ADIATEKPLRDTIQFLSDTVDQIINYTEEMSHA"
     gene            4928..5407
                     /locus_tag="VGY43_000873"
     CDS             4928..5407
                     /locus_tag="VGY43_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEQ4302072.1"
                     /translation="MPNLYDFTVKAQDGSDISLVNYKEKVVLVVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPCNQFLNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKD
                     ADPLFTWLKEEKSGPLGKRIEWNFAKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(5453..5836)
                     /locus_tag="VGY43_000874"
     CDS             complement(5453..5836)
                     /locus_tag="VGY43_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEQ4302073.1"
                     /translation="MNKGFKIGFLALVAMLLVACSQGTKQTQTPSVPKSDHHVRLVVK
                     EDTNTVDEKVSFEEGDTVLEILKDNYEVKEKDGFITAIDGIEQDMKANKYWLFKVNGK
                     MADKGANQITVKDGDSIEFYQEVFN"
     gene            complement(5820..6323)
                     /locus_tag="VGY43_000875"
     CDS             complement(5820..6323)
                     /locus_tag="VGY43_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ4302074.1"
                     /translation="MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFVLYPLSQQFPKYQLGCQ
                     AFLVALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVIMMLFRR
                     LIGEQRI"
     gene            6648..7496
                     /locus_tag="VGY43_000876"
     CDS             6648..7496
                     /locus_tag="VGY43_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEQ4302075.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPSKAKASTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDAV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     regulatory      7623..7719
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            7764..8327
                     /gene="thiT"
                     /locus_tag="VGY43_000877"
     CDS             7764..8327
                     /gene="thiT"
                     /locus_tag="VGY43_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEQ4302076.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMALSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSDSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     gene            8418..8897
                     /locus_tag="VGY43_000878"
     CDS             8418..8897
                     /locus_tag="VGY43_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEQ4302077.1"
                     /translation="MAKKTKLKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            9238..9861
                     /locus_tag="VGY43_000879"
     CDS             9238..9861
                     /locus_tag="VGY43_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEQ4302078.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEEAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKITTMAAIY
                     PQQMLAFRENLAQFKPDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNASLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(9969..10871)
                     /locus_tag="VGY43_000880"
     CDS             complement(9969..10871)
                     /locus_tag="VGY43_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEQ4302079.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRGRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDINDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            11045..12538
                     /gene="lysS"
                     /locus_tag="VGY43_000881"
     CDS             11045..12538
                     /gene="lysS"
                     /locus_tag="VGY43_000881"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEQ4302080.1"
                     /translation="MSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVG
                     FWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            12674..12814
                     /locus_tag="VGY43_000882"
     CDS             12674..12814
                     /locus_tag="VGY43_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302081.1"
                     /translation="MTKEYISYISAAIFLLYGLLAAKWIFLGLGLILVLVGLADRLQS
                     KK"
     gene            complement(12917..13129)
                     /locus_tag="VGY43_000883"
     CDS             complement(12917..13129)
                     /locus_tag="VGY43_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEQ4302082.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(13339..14625)
                     /locus_tag="VGY43_000884"
     CDS             complement(13339..14625)
                     /locus_tag="VGY43_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ4302083.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            complement(14727..15653)
                     /locus_tag="VGY43_000885"
     CDS             complement(14727..15653)
                     /locus_tag="VGY43_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEQ4302084.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQIAKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            15857..16141
                     /locus_tag="VGY43_000886"
     CDS             15857..16141
                     /locus_tag="VGY43_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEQ4302085.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLFAKVIKSLLM"
     gene            complement(16300..16728)
                     /locus_tag="VGY43_000887"
     CDS             complement(16300..16728)
                     /locus_tag="VGY43_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEQ4302086.1"
                     /translation="MNKSFKNLVIGAASGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     LAEVEAKEKQDDVIIDLNEEDIIIDYTEQEEPVSDTLDKH"
     gene            complement(16721..17128)
                     /locus_tag="VGY43_000888"
     CDS             complement(16721..17128)
                     /locus_tag="VGY43_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEQ4302087.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            complement(17150..17929)
                     /locus_tag="VGY43_000889"
     CDS             complement(17150..17929)
                     /locus_tag="VGY43_000889"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEQ4302088.1"
                     /translation="MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESFWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            complement(17926..18858)
                     /locus_tag="VGY43_000890"
     CDS             complement(17926..18858)
                     /locus_tag="VGY43_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEQ4302089.1"
                     /translation="MTVTVKMLVQKVKLNVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            complement(19223..19495)
                     /locus_tag="VGY43_000891"
     CDS             complement(19223..19495)
                     /locus_tag="VGY43_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEQ4302090.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            complement(19559..19996)
                     /locus_tag="VGY43_000892"
     CDS             complement(19559..19996)
                     /locus_tag="VGY43_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEQ4302091.1"
                     /translation="MTLTNYVQEVSLADFGKPFHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIVRHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVSTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            complement(19983..22115)
                     /locus_tag="VGY43_000893"
     CDS             complement(19983..22115)
                     /locus_tag="VGY43_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEQ4302092.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFSVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            22349..22504
                     /locus_tag="VGY43_000894"
     CDS             22349..22504
                     /locus_tag="VGY43_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302093.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            22652..23554
                     /locus_tag="VGY43_000895"
     CDS             22652..23554
                     /locus_tag="VGY43_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEQ4302094.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKAFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            23554..24369
                     /locus_tag="VGY43_000896"
     CDS             23554..24369
                     /locus_tag="VGY43_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEQ4302095.1"
                     /translation="MIRFLILAGYFELTMYLQLSGKLDQYINVRYSYLAYISMILSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFLDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLAEVHQTKEPNNPYVYRVF"
     gene            complement(24468..25892)
                     /locus_tag="VGY43_000897"
     CDS             complement(24468..25892)
                     /locus_tag="VGY43_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ4302096.1"
                     /translation="MGIFSKDFLWGGAVAANQVEGAFEADAKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(25911..27773)
                     /locus_tag="VGY43_000898"
     CDS             complement(25911..27773)
                     /locus_tag="VGY43_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEQ4302097.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLTMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGAATIVLAFSLTWFMGIDEE
                     SPEQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSE
                     GVVYAPFDGEVITFFPTKHAVALKNTRGVEVLIHVGIDTVELKGQGFEQLVSVGDVVK
                     RGQALLKMDTDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
     gene            complement(27775..28617)
                     /locus_tag="VGY43_000899"
     CDS             complement(27775..28617)
                     /locus_tag="VGY43_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEQ4302098.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFVLKNSDNMNRFTELFITVPQEVVACSERIINLGKIKLGKTLDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSE
                     MSYDDDDAELLLVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            28945..30312
                     /locus_tag="VGY43_000900"
     CDS             28945..30312
                     /locus_tag="VGY43_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ4302099.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTQSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPFDWLAFIALSISLTSALLA
                     ITSLENGSVNLYYLGLFILSFVLFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQPEFTSGVQSVYLLFTIFALLDFIFFFAMFYHLG
                     KKGLA"
     gene            complement(30366..31916)
                     /gene="ftsY"
                     /locus_tag="VGY43_000901"
     CDS             complement(30366..31916)
                     /gene="ftsY"
                     /locus_tag="VGY43_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEQ4302100.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDK
                     IEAVQQEDVSSEGAGSVENGPEAASVNAQVEEETGDNSNHPSEDTNKFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSANEEAVDTSKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATYDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KEVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(31916..32740)
                     /locus_tag="VGY43_000902"
     CDS             complement(31916..32740)
                     /locus_tag="VGY43_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ4302101.1"
                     /translation="MNIRILALDLDGTLYNTEKIVTDANKKALAAVREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKDIIYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKAVADAVTTLTNDESGVAEAVKTFILEEES"
     gene            complement(32744..33541)
                     /locus_tag="VGY43_000903"
     CDS             complement(32744..33541)
                     /locus_tag="VGY43_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEQ4302102.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYRGEILFADMMTKEQYTEVAKKILANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            33846..34973
                     /locus_tag="VGY43_000904"
                     /pseudo
     CDS             33846..34973
                     /locus_tag="VGY43_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(35344..35643)
                     /locus_tag="VGY43_000905"
     CDS             complement(35344..35643)
                     /locus_tag="VGY43_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302103.1"
                     /translation="MGIGTTVLSQEIEYEIEDRIMILVEKIDVKIYKNCLELANKISG
                     YHCSVFEFPYKKIKKFFKHELYSRHHYIIVRLDGSMEYRFSSVALKNKIKSILDS"
BASE COUNT        10710 a         7589 c         6370 g        11049 t
ORIGIN      
        1 aatcttcata gttttccctc tacttcttga gataatcatt tagcattata acatctttct
       61 atatcaaaca aaaggaaaag tcaagaatcc tcaaaaaaag aagctccaag ggctaacctt
      121 taaaattctg attagtcact tgaaaacttc tataaatacc aattaatact caagggcatt
      181 agcctgaatt acgtaaacca gtcgctatgc cattgatagt tgtatggatc aatttttcat
      241 cattttcgtc aagttgatta ttacgccaac gtttaatcaa ttcaatttga atatagttca
      301 acacattaaa atacggcaag cgtgacttca agctatgctt aagggaagga ttatcctcca
      361 atagatcatc atggtcttgg atagcaagaa taacattttt tgtcaattgc cactcatcca
      421 aaatctcata aaaaacatct cgaacatcct gactttcagc tagttgtgca tactgaaagg
      481 caatattcat gtttgattta gataatacca tatcaacatt tgataacaag gaatggaaaa
      541 aaggccacgt ctgatacatg tgttggaggc gttcaaggtt actttgtgct cggtcaatat
      601 aacgtttaaa ggctgaacct accccatacc aacctgggaa catgatacga ttttgtgacc
      661 atgaaaagac ccaaggaatg gcacgcaagc ctgtaatttc cgtaatcgtt ttacgggctg
      721 ctggtcttga cccaatgttg agactggaaa cttccttaat cgggcttgcc tcaaagaaat
      781 aatcatagaa atggggattg tcaaaaacca attttcgata aatggtattg ctatcagcaa
      841 caatgctatc catgatttct cgaaaactat caatctcatt aggatctgtt atcatttgag
      901 tcaccatacg attgatagaa gctgaaatca acatttctaa atggtaataa gccacatctt
      961 tattgccgta tttgttttca ataatttccc cttgctctgt cagacgaatc cgatctttga
     1021 tggaaccaaa aggttgtgaa gtaatggcat cataagaagg gccacctcct cgaccaactg
     1081 ttcctccacg accatggaag aaggtgattt tcactccatg ttcctcacca atagctgtta
     1141 attcattctg agctttataa agagtccaac ccgatgccaa gtagccacca tctttattac
     1201 tgtcagaata gcctaacatg atttcttggt aattacgatt cgttgcaatc caagatttga
     1261 caatgtcatg gcttaaatag gctgccatga tgtcacgggc attatctaaa tcctcaatgg
     1321 tttcaaagag gggaacaatt tgcacacgag cccgctgctg gtcaaccaat cccacttctt
     1381 taagcataat ggccaactca aacatatcag agacactttc tgtatgtgaa ataatatgtt
     1441 gcttaataac ctcttctcca agcttatctt tcaattctcg tgccgtagta tagatagcca
     1501 gttctttttc taataggtct gatttagcaa ctgccgctga ggataaggtt cttggctcct
     1561 ccattaattg ttgtaagaga acatcgcatt tttcagtttc tgaaagagag ctataatcgt
     1621 caacaatatt ggctcctttt aataactctg ccacacaagc ttcttggaca ctggagtctt
     1681 gcctcatgtc aatgcttgct aagaagaagc caaaaatatc aacagcttgc atgacttctc
     1741 gcaaatcccc ctcaatcaaa gcggagttgc cattatcaag tagcgactgc tcaatagcct
     1801 ttaaatcagc tttaaaatca acaggagagt cataggctaa gatgggtttt tctaaactag
     1861 ctggtgaggg ccaagcagat gtgtttagtc ccacactact attcatacga gctgctggct
     1921 gattagttag ttgaatttgt gtttgtttaa gacgcgattg aatataatga aaagctctgc
     1981 gataaggttc atttccacgg taaatcgatt ggtcctgaga caaactggct aaacgttcca
     2041 cttccgagtt gggttgtacc aaggttgacg acagtgaaaa tgttcggtaa agggctgcta
     2101 atttgtcaat gtagtaattg aggataacct cactttgaac cgtagctgac aagcacaagg
     2161 tttcagctgt gacaaagggg ttgccatcac ggtccccacc aatccacatc cccatggtaa
     2221 tgggtttggg attgtctaac tctagaccgt gtttttgggc taagtttttg tactctgttg
     2281 tcaacttggt cactgcttga atgagagaac catcgtaata ctgcatgaca ttttttatct
     2341 cgtttttcac ctgaagcttt ttctcgcgaa taatatctgt ctgcatgatc atttcaatat
     2401 aacgatatag ctcctgacgc catttctcaa gattaatcac accagcctta gcatcacggt
     2461 atttgcgcag aagtttatga atgtgagttg tcaattccag aatcgtttta cgttgtactt
     2521 gcgtcggatg tgctgttaaa acaggaacca cattaacctg ctccaaaatg tctttaccat
     2581 tatcttttcc agcaagatcc ttgatggtta gggctaattt tcctaaataa tcagtatccg
     2641 tattattttg atgattaatt tcataggcta aatcgacatc ttctgaaata ttgattagca
     2701 agggtaaaat agaaaaatac ctggaaatca cttccatttc ttgatttgaa atattggcga
     2761 caactttttc taattctatg taatcttgtt tttcagataa caccataata gactcgataa
     2821 ctgtaaacgc atcatctcca atcatccgtc gtgtgatatt ttccaacatt tctttcaaaa
     2881 gagcaacttc ttcagcaatg atagtttgat tgttactact ctctaacttt ttaagtggca
     2941 aatgaccatc tccttctttg ctagtttctt ctatcatacc actttttacc aaaaataaaa
     3001 gtgagcatgt tcataacgtt tgttttttaa caaaagtaag cgctttattt caaaaaatgt
     3061 ttggataggt ttagtctcca tattccacta aaattctgtt atactagtct tgactatatt
     3121 gttaaggaga caactatgga attgaaaaaa cgttcagaat tccctgaaaa tgaactttgg
     3181 gatctaacag cgctctacaa agaccgccaa gattttttac tcgctattga agaagcctta
     3241 caagatattg acctgtttaa gcgcaattat gaagaccgct taacatcggt ggacgatttc
     3301 actcaggcct taatagaaat tgagcatatt tatactcaaa tgagtcatat tggcacttat
     3361 gcctttatgc ctcaaaccac tgacttttca gatgaaagtt ttgctcaaat tgctcaggct
     3421 ggcgatgatt tcatgactaa agctagcgtt gcccttagct tctttgacac cgccttagcc
     3481 aatgccgacc ttgacgtgtt agatacatta gaaaagaacc cttatttcag cgcagctatt
     3541 cgcatggcaa aaatccaaaa agaacacctc ttaagtcctg atgtggaaaa ggctttggct
     3601 aacttacgcg aggttatcaa tgcgccctat gatatttaca ccaaaatgcg ggctggtgac
     3661 tttgacatgg atgattttga ggtggatggt aaaacctata aaaatagctt tgtttcttac
     3721 gaaaatttct atcaaaatca cgaaaatgct gaaattcgtg acaaagcttt ccgttccttc
     3781 tcaaaaggtc tccgtaaaca ccaaaatact gctgctgctg cttatttggc caaggttaaa
     3841 tctgaaaaat tgttagctga tatgaaaggc tacacttctg tctttgatta cctcctagct
     3901 gaacaggaag tggatcgtag cttgttcgac cgccaaattg acctcatcat gactgaattt
     3961 ggaccggttg ctcagaaatt cttaaaacat gtcgcccaag tcaatggtct tgagaaaatg
     4021 acttttgctg actggaagct agatattgac aatgatctca atccagaagt cagcattgat
     4081 ggtgcctatg acctcgtgat gaagtcttta gccccattag gacaagaata cacgaaagaa
     4141 atcgaacgtt atcagacaga acgctgggtt gactttgctg ctaatgccaa taaagattct
     4201 ggtggttatg ccgctgatcc ttacaaggtc catccgtatg tcttaatgag ctggactggc
     4261 agaatgtctg atgtctacac gctcattcat gaaatcggac actctggcca atttattttc
     4321 tctgataatc accaaagtta cttcaacacc catatgtcaa cttattacgt cgaagcgcca
     4381 tcgaccttta atgaattgat gcttagtgat tacttggaac atcagtttga tgaccctcgt
     4441 caaaaacgtt ttgctcttgc tcaccgttta acagacacct actttcataa cttcatcact
     4501 cacctattgg aagcggcttt ccaacgtaag gtttacaccc tgattgaaga aggcggtacc
     4561 tttggagctg accaattaaa tgcaatgatg aaagaggtct taacagactt ctggggagat
     4621 gccgttgaca ttgacgatga cgcagctctt acctggatgc gccaagcgca ttactacatg
     4681 ggcttatata gttataccta ttctgctggg cttgttatgt caacagctgg ttaccttaac
     4741 cttaaaaaca acccagatgg ggcaaaagaa tggcttgatt tcctaaaatc aggtggtagc
     4801 cgtacgcctc ttgatactgc aatgctcatt ggggcagaca ttgccactga aaagcctctt
     4861 cgagatacca ttcaattctt gagtgatacc gttgaccaaa ttatcaatta caccgaggag
     4921 atgtcacatg cctaatctct atgattttac ggttaaggct caggacggca gtgacatctc
     4981 actagttaac tacaaagaaa aagtggtttt ggtcgtgaat acagctacca aatgtgggct
     5041 aaccccacaa taccaggcct tgcaagcact atatgacaca taccatgaca agggatttga
     5101 ggtcttagat tttccttgca accaattttt aaatcaagct ccaggagatg ctgaggagat
     5161 taatcacttt tgcagtctga cctatcacac tactttccct cgctttgcaa aaatcaaagt
     5221 gaatggtaaa gacgctgatc ctttgttcac ctggttaaaa gaagaaaaaa gtgggcccct
     5281 cgggaaacgc atcgaatgga acttcgctaa atttctcatt gaccaaaatg gtcaagtcat
     5341 taaacgctat tcctcaaaga cagatcctaa actaattgaa gaagacctta aagcacttct
     5401 tggttaatat aaaatagact tggtgtgcca agtctatttt atattatagt tactaattaa
     5461 aaacttcttg ataaaattca atgctatcac catctttaac ggtaatttga ttggcaccct
     5521 tatctgccat ctttccattc accttaaaaa gccagtattt gttagctttc atatcttgtt
     5581 caataccatc aatagcagtg ataaagccat ctttttcttt gacctcataa ttatctttga
     5641 gaatctcaag cactgtgtct ccttcctcaa aagaaacttt ttcgtcaaca gtattggtgt
     5701 cttctttaac aactaagcga acgtgatggt ctgatttggg aacgcttgga gtctgtgttt
     5761 gttttgttcc ttgcgagcaa gccactagta gcatagcaac aagtgctaaa aatcctattt
     5821 taaatccttt gttcaccgat taacctccta aataacatca taataactgg aaaaaagacg
     5881 agagttgata aagcatgcgc tatattaaag ggcatccctg ctaaaacata gctccaccaa
     5941 ggcatactat ataaatacgc aaaacaagta tctatcagca ccccataaag gaggccacat
     6001 aaggcgacca agaaagcctg acagccaagc tgatatttgg ggaattgctg agacaaaggg
     6061 tacaagacaa aacgccataa caaaagaaca agcacaaaac aagtaacttg ccaaaagacc
     6121 caagggccaa atcccagcaa aaaggctgat aaaaacaagc acaacatcat aactaataca
     6181 gcctcggcta acccaaagta aagaagataa ctgagtaaaa atgccgtcac aggctgcacg
     6241 ttaggcaggc tgctaaaaac cattctcaac acaacacata gggctgacat gatagcaatg
     6301 cgactcataa gcttagctga cataaacttc ttcctcgttt ttttctctat tatgacagat
     6361 ttacaaagcg tttaccagtt tggagctcac ttatttatca aatgataata acatgagaat
     6421 taaataacaa aacagtactt gctgactgtc atgatatagt caaagactaa actaatattg
     6481 taaagaatat agctaccaac tataagagat agtgacataa acttgacata gttagagagg
     6541 atctcatttg taacttctca aagagaatac cttaaaatgc aagacaatat aagaaaacag
     6601 ttaggatatt ttgatttttt ttagtaatta gggtacaata acagttaatg agaagaaaaa
     6661 taaaacctat tgttgtgcta gtcttcttta ttttactggc aatggtattg attatcggaa
     6721 aaagacaagc taatcatgcg aaacaaaaag aagttgaaga cgctaagagt catattccta
     6781 ttgcaaccag taatcctagt aaagcaaaag ctagcacttc tgaaaccgaa gactttattt
     6841 taaatcctat tgttgatgtt tccggctggc aactccctga agaaattgat tatgacacat
     6901 tgtcacgtca catctctggc gcaattgtac gtgtctatgg aggatcgcaa attacagctc
     6961 ataacaacgc tgcttttaca actggaattg acaaatcttt taaaacgcat atcaaagaat
     7021 ttcaaaaacg aaatgttcct gtagctgttt acagttacgc acttggtcgt agtactaaag
     7081 agatgaaaga agaggcccga gctttctaca aaaacgctgc tccctataat ccaacttact
     7141 actggattga tgtcgaagaa gccactatga aagatatgaa taaaggcgta acagccttcc
     7201 gagaagagct taaaaaactt ggtgctgaaa atgttggtct ctatattgga acttatttta
     7261 tggcagaaca agatatttca acaaaaggtt tcgatgctgt atggattccg acttatggta
     7321 gtgattctgg ctattatgag gctgctccta atacaacctt agattacgat ttacaccaat
     7381 atacctcaca aggttatctc agtggtttta acaatgcttt agatttaaat caaattgccg
     7441 taacaaaaga cactaaaaaa acgtttgaga agttatttgg caactccaac aattaagagg
     7501 ttagcatcat ggctaatctt ttttgtagtt tacatcttac caagaaaaac tctaggtcaa
     7561 taatttaacc ccccttatcc ttgacaagga gattatctca tcatataatg aaagcactat
     7621 aatatttcac aaaggagtgc tttggctgag atcgcaattg cgaaatcctg aggacctgat
     7681 cttgttagta caagcgtagg gattgtgacc aataatcaat gattggaaag cgatactctt
     7741 tttgtgcaca aaaggagttt tttatgtcac caaacaccaa tgtcaaatac cttatcgaag
     7801 ctgctatttt tgctgcattg gcgatggccc tttcatttat tccagatttt gctggctggt
     7861 ttagtccttc ttatggtgct attgcactgg ttattttctc tttgcgccgt gggttaaagt
     7921 acggcatgtt ggcgggtctc atttgggggc tgcttcactt tgtacttgga aaagtttact
     7981 atctcagcat gtcccaagtc tttattgaat atatcttagc ctttacctct atgggattag
     8041 ccggtagttt ctctgatagt ttgattaaaa ctttaagaag acaacaaacc ttttttgccg
     8101 tttttcttgc aataatggct agtttactag ccgttacagt acgttacttg tggcacttcc
     8161 ttgcaggaat cattttctgg ggcagttacg cccctaaagg catgtccgct gtctggtatt
     8221 cttttagcgt taatggtaca gctggtgtcc taactttttt aataacatgt ttagcgttaa
     8281 tgattgcttt accaattcat cctcaattat ttgatcccaa agactaattt ttagtcattt
     8341 gaatcttaca ttaaaaaaat ggtataataa tgttgttata ccattttttt atgtttagat
     8401 aaaggtaagg acttgatatg gctaaaaaaa caaaactcaa aaaaacctta gtagaacaaa
     8461 tcctcgataa ggctaatatt gctcatcaag gactcaagct taatgcttta gaaggcgact
     8521 ttccagatga ccttcaacca tcagatattt acaagacact tgctctgact ggtgatcaaa
     8581 caggtcctct aattggcatt attccattaa cagaacactt atcagaaaaa caattggcaa
     8641 aagtatcagg taacaaaaaa gtgtccatgg ttcctcaaaa agacttgcaa aagacaacag
     8701 gctatattca cggtgccaat aatcctgttg ggattcgtca aaaacattca tatcctattt
     8761 ttattgacca aactgcactg gaaaaaggtc aaataatcgt ttcagctggt gaagttgggc
     8821 gttctataaa gatttctagc caggctctag ctgatttcgt tggcgcaagc tttgctgatt
     8881 taaagaagag aaaatgaaca ctactgccaa ctttatctgg tttctttttt aagtttttcg
     8941 ccttgattaa gctagtcttt gtttagtatt attttgatct caactgcttt aacattgatc
     9001 ctgttaatct ttttcttttg tagagacttg atatcacgac aaattcaggt cgatttgtct
     9061 tagatctaat atgggcttta cactttaatc agaacctagc tattatacac ttatactacg
     9121 cttttttact ttatcttttc actataggta ttatttttgc ttggtgatgc ctaaactttt
     9181 tctggttact tttttatttt tagcgctcgc atcagttatc tctaaaagga ggcttaaatg
     9241 aaattatatt ttgtaagaca tgggaaaacc ctttggaatt tagaaggtcg ctttcaaggc
     9301 gctgggggcg attcgccatt acttgaagag gcaaaagacg aaattcactt acttggcaaa
     9361 gagttagcta aggtggcttt tgatgccgtt tatactagcg accttcaaag agctatggca
     9421 acagcagcta ttatcttaga tgcttttgac caacagccaa aactttacca caccgaccag
     9481 cttcgggagt ggagattagg taaactggaa ggggctaaaa taacaacaat ggcagctata
     9541 tatccccaac aaatgctggc ttttcgggag aatctagccc agttcaaacc agatcagttc
     9601 gaggctgaat caatttacca aacgactcaa cgtgtctgcc atcttatcca atcgtttaaa
     9661 gataaacatt atcaaaacgt tcttattgta ggacacggcg ctaacttaac agcaactatt
     9721 cgctcattat taggttttga acctgctctt ttactcgcta aaggtggctt agataatgcc
     9781 agtcttacta ttcttgaaac taaagattat ttaacttatg actgtttaat ttggaatgat
     9841 aaatcttttc tagaggtgta aaaccactag acaataataa aaaaagctaa cacattgatt
     9901 tcttactgac aagacactca ctttgctagc tttttttatt attatctaat gggctattat
     9961 ggtttcatct atctggcata ttttaagcgc aaaacttttt cttgctgctt ggttaaccga
    10021 agcaagataa ccactttgtc aatgctcatg ttactttcaa gtaaacgctc tgctgccatc
    10081 atcaagccgt tgttgatacc catctgtaaa attggatttt tcttgtcatt aatatcaaaa
    10141 ataaatttat tatcaggtaa atcaaagagt actttaacgg caccaaagag ctgttcaaag
    10201 ttatcaatag ccacatcata aacaggctta gtgcctggtt ttagctgacg acctctatga
    10261 ttaaaccaca tggaatgcca accaccatta aaggcaccca tgatatcatt gtcataagag
    10321 tccccaacat atagtgtggt ttgtgggttc atgtcaaatt gttctgctgc caggttaaaa
    10381 atttcttttt ctggtttttg aaagcctgtt gcttggctca caatgacacg cttaggatca
    10441 atataatcat aaagccctaa tttacgaact tttttcagct gatgttctgt tggcccattg
    10501 gtaataatcc ccataggaac attctttgat tttaaaaagt caagggtcat gcgcatctca
    10561 tctaacatgg taatgttctc aagttcgtgc tcatagactt cttgaaaatg tactcccgca
    10621 gcttcgtcga tttctcgata gccaaactca agcagtgttt ccttgcaacg ccagaatcgg
    10681 aaatattctg tggtccactc ccctgccatt actcttggga atccaacatc tgaatagtga
    10741 cgaaagcgaa tataagcttg attcattact gacatatcaa aatctgggaa gcacttttcc
    10801 atggcgattc gataaggcgc ttgctggtcg taaattgtgt catccacatc aaaaacaata
    10861 gcagtaatca tgagtctctt ttcttttcta gtttaatatc ccaatcatta tactattttc
    10921 catttggctt ttcaatttta ttttcaaaaa agtgccccgc tgcagtcgca ttttccaacg
    10981 aaatataggt gtattctagc ctcttttatg atacaatgga aaggaaatcg tattggagga
    11041 aaatatgtct aatcaacaca tcgaagaatt aaatgaccaa cagattgtcc gtcgtgaaaa
    11101 gatgatggct ctggctgaac aaggaattga tcctttcggt aaacgctttg accgcacagc
    11161 caattctgct gaattaaaag aaaagtatgc tgataaaaca aaagaagaat tacatgagtt
    11221 aaacgaaaca gctattgttg ctggccgctt gatgacaaaa cgtggcaaag gtaaggttgg
    11281 ttttgctcat cttcaagacc gtgaaggcca aatccaactt tatgttcgca aggactctgt
    11341 tggcgaagac aactatgaaa tcttcaaaaa agccgattta ggcgacttta tcggcgttga
    11401 aggcgaagtc atgcgtacag acatgggcga gttgtcaatc aaggcaacca agttgactca
    11461 cctttctaaa tcacttcgtc ctcttcctga aaaattccac ggattaactg atattgaaac
    11521 catttaccgt aagcgtcacc ttgatttaat ttcaaatcgt gaaagctttg accgcttcgt
    11581 gacccgttcc aaaatgattt cagaaatccg tcgttattta gacggtcttg atttcctaga
    11641 agtagaaacg cctgtgcttc ataacgaggc tggtggtgct gctgctcgtc ctttcgttac
    11701 tcaccataat gctcaaaaca ttgatatggt tcttcgtatc gcaacagaac ttcatttgaa
    11761 acgtttgatt gttggtggta tggaacgtgt ctatgaaatt ggtcgtatct tccgtaacga
    11821 gggaatggat gctactcata atcctgagtt cacttctatt gaggtttacc aagcctatgc
    11881 agactatctt gatatcatga acctgacaga aggcattatc caacatgctg ctaaagctgt
    11941 taaaggtgat ggccctattg attatcaagg aactgaaatc cgtatcaatg aacctttcaa
    12001 acgtgtccac atggtagatg ctatcaagga agtgacaggt gttggtttct ggcctgaaat
    12061 gactgtcgaa gaagctattg cacttgccaa agaaaaacag gtcccactcg aaaaacactt
    12121 cacaagtgtc ggacatatca tcaatgcttt cttcgaagaa ttcgttgaag aaaccttagt
    12181 ccaaccaacc tttgtgtttg gtcatcctgt tgaagtatcg cctttggcta agaagaatcc
    12241 agaagatacc cgcttcaccg accgcttcga acttttcatc atgaccaaag aatacgccaa
    12301 tgctttcaca gagttgaatg atcccattga ccaattatct cgttttgaag cacaagcaca
    12361 agccaaagaa cttggtgatg acgaagcaac tggcattgac tacgacttcg ttgaagctct
    12421 tgaatatggt atgccgccaa ccggtggact cggaatcggg attgatcgtc tttgcatgtt
    12481 attaacaaac acaacaacaa tcagagatgt gcttttattc ccaacgatga aaccttaact
    12541 tttttaagat ttgtattcat atcttaaaac cgataagtgg caatataaca taacgtttta
    12601 ttatctctaa ccagtcttca ttaccatgaa gactggttta ttaacagtag cttatagaaa
    12661 gtgacttaac aagatgacca aagaatatat ctcctacatt agtgctgcta tcttcttgct
    12721 ttatggcctt ttagctgcca aatggatttt tcttgggcta ggcttaattt tggtacttgt
    12781 cggccttgct gaccgtcttc aatctaaaaa ataacccttc tccgtgtcaa ctgcacccga
    12841 ttaccagcct taaaatggcc aagatgtcaa ggtgcagttg actagaaggg ttatttttta
    12901 caaccacaga gaggttttac ttacgaaaag cgtctaagat ggttttaaat tcttcattag
    12961 taagagtaat gcctttcccc attttcgtat ggtctggact ccacgtgcgg atgtcccatt
    13021 tcgcttctgc gccattaaag ctgacgcggt tcaattcttt cgtccaacct ttatcatttt
    13081 ctgataaggt gagtaaatgt tcctcaatgt tgaatgtaaa ttctgccatt agttttcctc
    13141 ctcatctata ctattcgaaa ttaaagtgga aaaaatcatc tttttttcac tttttttatg
    13201 actcattctc ctattattct atcaagtttt gagaaaataa gctattgtga tatccaattt
    13261 tcaaaaaaaa caggctctct tttcccaact atggtcgtat accatttgga aaaagagggc
    13321 ctctagtatt tcttgttact atgttctaac agttttactg gtgccatctt tttgatagag
    13381 gttgacaaga ccttccttgc aagccctaat catatcccct ggcttaactt ctctcggtaa
    13441 agagatggtt aagagttcca ttggatttgg ggcacggtca atcttttggc catccgcatc
    13501 atgtaagtcc ttaacaaccg tttcaaaatg acggaaacct ggtccataac attcaatccg
    13561 atcgccttcc atgatgacat tacgctgacg aatggtcgct gtcatgctgg ctgagtcaaa
    13621 ggcaactact tctccgacaa atttatattg tggaattttg cggcgagcac caaataattg
    13681 ttcattttca gttgggatac catagtaaaa acctgtagcc aactcgcgct gggcaacctt
    13741 ccacaactcg tcaatcaatt cctctttgat agcataaaaa gcttctgggc tttccatgta
    13801 agcatctaca gccgccttgt aacagttggt tacggttgag acgtagtgga tagatttcat
    13861 tcggccttca atttttaagc tatcaacccc attttcaatc aggtcaggaa tatggtcaat
    13921 catacacatg tcaacagagg acatagaata gtcttctgga atttcccctt ttaaggagcg
    13981 gcgctctcct ccaaatggca tgtcatacaa atcatacttc cagcggcaag actgtgagca
    14041 gccgcccctg ttggcatcac ggtgactcat gtggtttgac aaaacacagc ggcctgaata
    14101 agagatacac atggctccat ggacaaaggc ttcaatttcc acatctgtcc gcttacggat
    14161 ttctgctaac tcggccatat taacctcacg agctaaaaca actcgggtca aacccatggc
    14221 tttccaaaat tcaaaggtct cgtaattggt agatgaagct tgcgttgaca aatgaatttc
    14281 caaacctggg gcttctgttg aacaaataac aatcaaggct ggatctgaaa caatgaccgc
    14341 atcaagcccc atatcacgca gttgacgaaa ccactcgccc gcaccaattt cgttcccttc
    14401 gtgggtaacc atgttggcag caacatagac cttagctcca cgcgcatgtg cataatcaat
    14461 gccttcttgc aattcttcca tagagaagtt accagcgcgg cttcttaggc cataggcctg
    14521 tcctccaaca aaaacagcat ctgcgccata gtcaatcgca acttttaatt tttcaagtgt
    14581 tccagcaggt gataagacct cgggacgttt tttcatatgt gacatgtgat attctttcta
    14641 ttttcaagat aggtagatta cctgtgtaat ggtgtcataa ccctgtcttg ccctgaaata
    14701 gtaaactcac tcaagacaag gattacttat ttaacggttt ttggatcgaa ctcataaaag
    14761 ccagtatcta atccacggcc agctggatga tgggcatgca ctgcttgatc aagcttttca
    14821 gcttcttctt gggtaaattg cccagcttct aataaggttt tagcctgaat aaacaattta
    14881 gtaatagcga caaaatcatc acctggacag taaatgccat ctagcttcca atgagttaag
    14941 ccatgcgcat acagctcacc caatttagac atcatgtcga tatcgttatt aatgaaaata
    15001 tgagtgccat gattgtcttc ataaatggag taatggctgc tagcatctcc tggttctgcc
    15061 aagaaaagtc ctcgttcacg actaacctca tcatcaatct ttgtaaaatg gtaataattt
    15121 tctagcaagg gacgtttcga gtgatgaatc accgaggcgc cgtaaactag cacctctgct
    15181 ggaaattcca aattttcagc taaggtgaat aactctgctg atgggatttc ccttgctaaa
    15241 acactttcaa cagcaccatg ttgcccccag aaatttacct gacggctaga agtcacaaaa
    15301 acagaggtat cataaatcag tttaaagtta tagccatccc ttttattgac ataaaacaca
    15361 cctgcatcac caaccacaag ataatcaaca gcaatctcta tcattaagtc taaaaagggt
    15421 ttgatctgat ccatcatatc ttgatgcatc aaagcattgc aagctactgt caactctttg
    15481 cctgcatcat gcactagttt ggcaatttgt ctcaattcat cataagaaaa attatgggga
    15541 aggcgtaacc cgtaattggc ttcaccaaca taaatacgat caacaccagc agctaataaa
    15601 gctttgactt gctcaatgct ttcagctgtg gctgtaataa ttattttttc catataagct
    15661 ttattatacc aaaaatttta agaccgtaag catctttctt gcaaaagccc aagcattaag
    15721 ctagtcccct tactgttata gcatgataag tcacttgtca ttagtaaatc ttttcaaatc
    15781 ttttaaaaaa agatgacaag aagagacttt tatgatagaa ttacttagta tgttaaggaa
    15841 aggagaggag aggactatgc ctgcaccgtt aaagaagcat aattcggttg aacaggatga
    15901 ttcttaccaa gaatctcaaa gtaaatttcg agattttcaa gagttcaatg gccaaagtgc
    15961 aaagctaaaa gaattagtct tctttgctcg tatcgctagt ttcagcctta ttaccgtttt
    16021 atttgcattt gtcctgctcg taatgaattt agcgccaatg tttgctttct tatttgcaag
    16081 catcattagc ttaggcatta cttccttatt cgccaaggtt atcaaatcat tactgatgta
    16141 acttccagag tccgttttac gtgactcttt ttttgtgtca aaaacaaaaa aagattgaag
    16201 ccacaatacc ccccttcttc agttagccta aaactaacca tcgggactag tgatcagatc
    16261 cttcaatctt ttcttcttct atgttttagg tcattttagt tagtgtttgt ctaatgtatc
    16321 actaacaggc tcctcttgtt cagtatagtc aatgatgatg tcttcttcat ttaaatcaat
    16381 gataacatca tcttgctttt ctttcgcttc aacttcggca agggtttctt ttgttttttg
    16441 cacgaaagct gttgttttat ctttgagcaa gtctaacatg tcctctttag ttaagtcacc
    16501 agaagccaac ttatctttca catcatagaa agtgtcacgt gctaaatggc tgtattcact
    16561 acctttttct ttagcaaatt ggtggtaatc atctggactt tctttgtagg cttgataagc
    16621 tttttcagca cgatttttca aagccttgcc tttttctgtt gataagaagt aagctgccgc
    16681 tactcctgaa gcagctccaa tcactaagtt tttgaaactt ttattcatgc ttttctcctt
    16741 tttttccaaa tacttttgag gctactttac caactaatgc taattttcca gcttttgaaa
    16801 cattacctgt agcattagtt gctttttgcc caaaatgcct tgcttgacta tttaaatctg
    16861 aaagactttc tgacaaatca gcaatagcaa caaacaatgg atcgatggtt gctactttac
    16921 cattaacatc ttcaacaagg atattagctt ttgctaaaat atcattagtt tgatgaagtg
    16981 tcacattaac atcacttgtc aatacagaaa tcgttttttt ggcttcatca attgtttctg
    17041 agactttctt taatacaata atcaagaaaa tcaccaaagc aacaaatgcg agtgcaataa
    17101 tcatcagtga gattccaact aagtccataa gtttctcctt tttctatcct tattcttgat
    17161 aataagaaat tcctttttga cgacgtcttt ttataacaaa gattaagcca ataataatta
    17221 ataaggcaga cacatattgg gagatgcgaa tacctaaaaa cataagacta tctgttcgca
    17281 taccttcaat gactagcctt ccactaccat accaaattaa gtaaaatgca aagatttctc
    17341 catctaatag gctttttggc ttacgacgcc acatcataat aatgacaaat cccaaaagat
    17401 tccaaaatga ttcatagaga aaggtcggaa tgcggtaact tccctctata aacatttgct
    17461 tttgaataaa gcttggtaag taatttaact ggctcacagc tttaccatag gcttcttggt
    17521 tgataaaatt tccccagcga ccgatagctt gagcgaccat gacacttggt gcggcaatat
    17581 ctaaaaaatg aatgggattg agcaccttgt tataacagta agccaaaagt acaagagctc
    17641 ctgtaatgag accgccataa atagcaatac cgccattcca aatggctatg atttcatcta
    17701 aatgcttgac ataataagac cattcaaaaa taacatagta aattcttgca ccaacaatag
    17761 caagtggaaa agcaatcaga ataaaatcga aaatagcgtc agatgatatt ccttttttgg
    17821 gtgcttcttt tgatgctaag taaaccgcca aaacaagtcc tgacaagata catagcgcat
    17881 accagtggat ggctagtgga ccacatttta aggcaatggg attgatcatt gactcacctc
    17941 atttttggtg attagttgag ttaaacgatc ttcaaaagtt tttgtagcat caaagcccat
    18001 ttctttagcc cgatgattca tcgcagcggc ttcaataacc actgaaacat ttcgacctgt
    18061 ttttaccgga atacgaatac gagggattct cactcctgag aaagttatct cctcattacc
    18121 gtttccgaga cgatcaaaaa ctttaccagc ctcaaagttt tcaaggtaaa tggccaattg
    18181 aacttgcgat gagtccttca cagcactagc tccataaagc gacatcacat caataatacc
    18241 taccccacga atttcaagca agtggcgcaa gatctctgct ggctctcccc aaagggtttc
    18301 ttcatctttg gcatagacat ccacacggtc atccgcaacc aaacgatgcc ctcgcttaac
    18361 taattctaaa ccagtctcac ttttaccaat tccagaatcc ccttggataa gaacccccat
    18421 accataaata tccattaaaa cgccgtgaac actagtacgt tcagctaaag aagcgtcaag
    18481 aaaataagac atttctccag ctaagcggct agttgaaaca cggctactta aaagtgaaat
    18541 accttcttct tttgcagctt gaaccatttc ttttggaatg gctaaatttc tagagacaac
    18601 cactgcagga gtgtcctttt tgaacatctc ttttaaaaca gaataacggt tgtgagaagt
    18661 catctgtgtc agataagacc actctttcat tccaaatagc tgcaaccttt ctggagcata
    18721 ataatcaaaa taaccagtca tttcaagacc tggacgtgaa atatctgatg ttgttatctc
    18781 ttttgacagc aagttatctg tagcataaac cacattaagt ttaacttttt gcactagcat
    18841 ctttacagta acggtcataa tttctccttt ttcaatatta taacacaaat cgaccgttag
    18901 acccttgcaa atactcattt tttcactact aaatgagaac aacgacacca aaaatggtct
    18961 tagctctatt aaaaactagg ttttatcatt tagagatatg agtcaaaaat aagacaatgg
    19021 caaacaaata ctttactagt atcattgagc aattagtgct tattatggtg tttaaaaagg
    19081 tatcatctta ctaagtcaaa aagcaaaaag ccttatcata gctgataaga cccttcgctt
    19141 acttacatat caaaacattt tattatcatc agttaatcac atggttgctc ttacgtgatg
    19201 aattatcatt ttaactgatt gtttaccaga accagccatc ttcttcttca tttaagacat
    19261 cagcgtcttt acgacgacga ggacctcggc cataacgttc ttcaagcaag tcttccttgt
    19321 aaggtaagaa gatggccaac aaaatataaa gcaaaactcc aaaaccagtt ccgtaaataa
    19381 gaagagccgc taagacacgc gctagagcaa gatcccaacc atacttatct gctaaaccag
    19441 caatgacacc tgcaaccaag cgattttttc gctgtttata gaatttagtt tccacgtttc
    19501 tttacctcct cattctatga tactagttta catttttttt cgcaaaataa aaccagtctt
    19561 acgactgatt tttttccata agtttcccgt ggcaatttcc acaaacatat ttagccagat
    19621 tgatacgcct ttttcgttga taaacctgcc cacaggtttg gcaactataa tgatgattag
    19681 tctttgattt agagctagtt gagacataac gaagcccgtt tacttgagct agcagatctt
    19741 tgaaatccct atctttatga tggtaccctc ttccttcaaa ataaagatgg taatggcaga
    19801 gctcatggcg aacaattttc cgaaaaataa gctcaccgtg ctcctcaagc atcctagggt
    19861 taaaatccaa atgaccatct tttggaaaaa agcgaccgcc agttgttttt aggcgcttgt
    19921 tccaataagc cttgtggtga aatggtttgc caaaatcagc cagggaaact tcttggacat
    19981 aattagtgag tgtcacgcgg tggcaatagg ctgagattga ccttgtggcg gtccaagtca
    20041 atcttagaga cccaaacagt taccaagtca cccactgaaa caacttgact agggtggttg
    20101 acaaaggttt tgctcatttc agaaatgtga ataagcccat cttcatgaac accaatgtct
    20161 acaaaagcac caaagtcaac gacgtttctc acagttcctt caagcttctg gccaatttcc
    20221 aaatctttca aatcaaggat atcttgacgt aagattggtg cttcaaagtc atcacgaagg
    20281 tcacgacccg gtttaaggag atcagcaatg atatctttaa gggtttcctg cccaatagcc
    20341 agtgtttctg ccatttgggg aacttgaact gctgctaaag ttgccttggc agcgtcgtcc
    20401 aagtcctgaa taccaagtac cttaaagagt tctttgactg ctgggtagga ctcggggtga
    20461 actcctgtgt tgtctaaaat atttttggct cctggaattc tgagaaaacc tgctgcttgc
    20521 tcaaacgcct tagctcctaa tcgaggcact tttttgatgt cagcgcgtga tgtcagtgct
    20581 ccattttctt cgcggtattt gacaatattt tctgaaatcg ttttgttcaa acctgacaca
    20641 tgtgctaata aagatggact agccgtgttc acattaacac cgacttggtt aaccacagta
    20701 tccacaacaa aaccaagatt ctcactcaac tttttctgac tcacatcgtg ctggtactga
    20761 ccgacgccaa tagatttagg atcaatttta accaattctg cgagtgggtc ttgcaagcga
    20821 cgagcaatag aaatagcaga gcgcttttcc actgtgaggt ctggaaactc atgacgggct
    20881 aactctgacg ctgaataaac cgaagcaccg ctttcgttaa cgatgacata ggacgtattt
    20941 gggaaatctt tcaaaacgtc tgctacaaag gcttcacttt cccgactggc tgttccgttt
    21001 ccaatggcaa taatatcaat ctggtaagtc tcaatgagct gagtcagtgt ttctttagct
    21061 gcttgaatct tcgtttggct agctggtgct acgggataaa taacctgagt agtcaacaat
    21121 tttccagtct gatcaacgat agccaatttt gcacctgttc gaaaggcagg gtcaaaccca
    21181 agaaccattt tcccttttaa aggagacact aacaaaagat gacggagatt ttcagaaaag
    21241 aggtggatag ccccatcttc tgcggcatca ctgagttctg aacgaacccg tctttccata
    21301 gctggaacaa ttttcttttt gatggtctga ttgatgacct cttcaatata agggttggtt
    21361 tctttgaacc gcacactgaa aaagcgttgc attttctcca agttatgctc aaaagacact
    21421 tttaagatgc ctaacttttc gccacggtta agggctaaag tacgatatcc ttgcatgtta
    21481 gacacttggt cagaaaaatc gtaatagatt tggaaaacct ttttctcatc caactgctca
    21541 tctttaagcg ttgatactaa gcggctgtac tgccaaatct cattgtaggt ccaagagcgt
    21601 aatttagcat cttctgacat ggcctccaca aggatgtcca cagctcctgc tagagcttct
    21661 tgtgggctgg caaatccttc tgtgacaaag ggttctgctg ctgtttcaag gttttgcgca
    21721 ttttgtaaaa tcaaacgtgc taatgggaac aagcctgctt cacgcgcaat cgtcgctttt
    21781 gtacggcgtt tttccttata aggcaggtac aactcttcca aatcagcgag tttttcggtt
    21841 gcttcaatac tcgttcgtaa ctgatctgtc agttttccct gttcctcaat tttagcgaga
    21901 atggttgctt tgcgctcatt cagggtagtg agagacttat ccatatcaat aatggactta
    21961 atcaccactt catctagatt tcctgttact tctttacggt aacgtgcaat aaagggaatg
    22021 gtattgcctt gtgctgttag ggcaagcacc tgttcaattt gatggagact aactgacaaa
    22081 gcctctgcaa tgttgtgatt attgttattt tccataatat tgctattata acacaaacta
    22141 tgttaatgca aaaaatgata gcgaaacatt gtcctaatat aaagttgcgt aaagaatcaa
    22201 aaaaagctac ttttagtaaa taactgacga aaccctaaat aacaatacct aattttaaaa
    22261 aagaaagaag taaacagcac ttccgctttg gcattgttct caaatgatag tataatagac
    22321 ttatcttgaa tgaaagaagg tcatagatat ggcaattacc cataaaaaaa atgatgaact
    22381 tgaaaaaatg ctagcaggct ttgcatcaat ccctagtttt gataagcctt tggaagtcaa
    22441 tactgatggt aaactagcga ccaaagaaaa aacgacagaa caaacaaaac caagcaaacc
    22501 atagctagtt tgtttcattc tcttaacata tcgtccattc gtttaaactg agttgagata
    22561 tttttagcga tcaggctaac aaaacgtatc agtcgaggct gaacattcgt gtttcagcct
    22621 cctcttttat catctagaaa ggatatggtg aatgtcactc ttttccaacc ttcctcccag
    22681 tgtcttgcaa tggtttgcga tttttatgtc cattatcatt gaagctcttc cttttgtgct
    22741 cctaggaact attttatctg gttgtattga agtctttgta acgccagaat tggttcaaaa
    22801 atacctacct aagcaaaaat gcttgcgcat tctgtttgga acctttgttg gatttgtttt
    22861 tccttcttgt gaatgcggga ttattcccat catcaaccgc tttttggaaa aaaaggtgcc
    22921 tagttatacg gccgtccctt ttctggcaac agcgcctatt attaatccta ttgttttgtt
    22981 cgctacttat tctgcttttg ggaattcttt gcgctttctg atacttcgct tggtcggtgc
    23041 tgcactagta gccattacac ttggggtaat gttagctttt attgtagatg ataacattct
    23101 caaggataat gctcaacccg tgcattttca tgattattct catgaaagct tgccaaaacg
    23161 catttatcta gcactggtac atgctattga tgaattcttc gacaccggta ggtatctcgt
    23221 atttggaacc ttgattgcct ctgccatgca aatatatgtc ccaactcgtg tgttgacaac
    23281 gattgggcac aatcccttga cagccatttt gatcatgatg ctgatggctt tcattctatc
    23341 attatgtagt gaagccgatg cctttatcgg agcttcctta ttatccacct ttggagtggc
    23401 tccagttctt gcctttcttt taattggtcc tatggtggat attaaaaacc ttatgatgat
    23461 ggtaaaggct tttaaaggac gcttcattgt ccaatttatc ggcgtatccg ttcttatgat
    23521 tgccgtttat tgtttacttg tgggggtgct ctaatgattc gctttttaat tttagctggc
    23581 tattttgaac taaccatgta tctccagctg tctggcaaac tggatcagta catcaatgtt
    23641 cggtattctt accttgctta tatttccatg attttatctt tcattttagc tcttgttcaa
    23701 ctctatacct ggatgaaaaa cattaaggta catagccatt taaccggaaa aatcgcaagg
    23761 ctgaccagtc cttttatctt ggtctttcct gttttgattg gtctccttgt gccgaccgtg
    23821 accttagatt ccaccacggt ttctgctaaa ggctatactt tcccattggc tgcaggagcc
    23881 tctaaaacgg gagtcagtga tgacggtacc accattcaat acctcaaacc tgataccagc
    23941 ctttacttta caaagtctgc ctaccaaaag gagatgcgtc aagaactcca taaatataaa
    24001 ggcaagaaac cggtcaccat taccactgaa aattatatgg aagtgatgga attgatctat
    24061 ctctacccag atgagtttct tgatcgtgac atccaataca ctggctttgt ttataacgaa
    24121 ccgggccatg acaactacca attccttttc cgcttcggca ttattcactg tattgccgac
    24181 tcaggagtgt acggactttt gaccacaggt aatcaaacca gctaccctaa caacacatgg
    24241 ctaacagtta aaggtcgcct tcatatggaa tatgataaaa acttagaaca acatctacct
    24301 gtccttcaac ttgctgaggt tcatcaaacc aaagaaccta ataatcctta tgtttaccgc
    24361 gttttttaaa gactaataaa aaagcacttg ttttttatca aaacaaatgc tttttgagtt
    24421 ttatcagtta gcataggaac agagtcacca tcttaaacaa gacctattta ggaaaaatta
    24481 tcctcaaggt aacgtccatt ggtttgaatg acttgtcggt accaatcaaa tgattttttc
    24541 ttatagcgtg tgagttgacc agtaccatca tcatttcggt caacataaat aaaaccgtag
    24601 cgcttactta attgggctgt tgacatagag acacaatcaa tacagcccca agcagtgtaa
    24661 cccatgacct caacgccatc ttcaatcgct ttggcaactt gtacgagatg ctgactcatg
    24721 tagtcaatgc gataatcatc gtgaaccgtc atgctgccat ctgcggtttg caccagctga
    24781 tcctttgcac ctaagccatt ttcaacaata aacaaaggaa tctggtagcg gtcatagtac
    24841 tgattcaaga ccaatcgcag accaattggg tctatctgcc aaccccactc tgaagattct
    24901 aaatatggat tggacaaacc acctagaata tttccctgac cagatgtgta agcttcagga
    24961 ttgtgggctt gtgtgacact catgtaatag ctaaaggata gaaaatcaac cgtatgttcc
    25021 gctaataatt ccttgtctcc gtcttcaaaa acaatctcaa tcccattttc tttaaaatac
    25081 gacttaatat atgaaggata cttgcctctc acatgaatat ctgaaaataa gagattaaga
    25141 ttttcaaatg catgcgcagc aagtatatca cgaggatcag aggtcattgg gtaagcaggc
    25201 atcgccaaaa tcatacaccc aactttaaca tcaggattga tttcatgcgc tagctttgtg
    25261 acactagcag atgctaccaa ttcatgatga atagcttggt ataaatcttg caggctcagc
    25321 ttttcttttt ctgtcatgat gccaccactg gtaaagggca tgtgtaaaat cgagttgact
    25381 tcgttgaagg tcaaccagta tttgactttg tccttatagc gttccatgac tgtctgagca
    25441 aagcgctcaa aaaagccaat cagacgtcta tctgtccaac cattataggc tttggccaaa
    25501 tgcagaggtg tctcataatg cgacaaggtc actaagggtt cgataccata gttcaacaat
    25561 tcatcgaata agtcatcata aaattgcaaa cctgcttcat tgggctggtc atcgtcacca
    25621 tttggaaaaa tacgagacca agcaatagac gttcgaaaga ctttaaagcc catctcggca
    25681 aaaagagcaa tgtcttcttt gtagcggtgg taaaaatcaa tcgcctctaa agttaaatta
    25741 tcgctggtag gactatctgt ccattctcct agcccaccat ttggtagaac atcttgtacg
    25801 gacaaacctt ttgcgtctgc ctcaaatgct ccttccactt ggttggcagc tactgcgccg
    25861 ccccataaga aatcttttga aaaaattccc attctccctc tccttttagg ttataaaatg
    25921 actaacaaag cgtcctcttt agtcaccatt tttttgtcat cttgaataat aatctccaac
    25981 tgctcagccg aattggtcac gaccacagga ctgatgagtg aatagccttt tgaagtaatg
    26041 aaatcagtat ccatttttag aagtgcctgg cctcgtttca cgacatcgcc aacagacact
    26101 aactgctcga aaccttgccc ttttaactca accgtatcaa taccgacatg aatcaagact
    26161 tccacaccac gtgtgttttt taaggcaaca gcatgcttgg ttggaaagaa agtgatgact
    26221 tcaccatcaa agggggcata gaccacacct tcgcttggta atatggcaaa tccttctcct
    26281 aataacttgg aagaaaaggt ttcatcagga acttctgata gaaaaagcat ctcacctgtc
    26341 attggagcat acaacgtttg tttggttgac aagccgctct taacttgtga catatctgct
    26401 gcaacactca cttgctctgg ggattcttca tcaattccca tgaaccaagt caaactgaag
    26461 gctaacacaa tcgtcgcagc tccggcaatc aaagcatttg taaaattagc tccgcctgat
    26521 gggttgatgt actgtggtaa accaataata gaaggtacga caaaggtata agaagcaata
    26581 ttgacaaaac caataaaggc tccgaccaga ccacctgaaa tcatggctgc atagagtggc
    26641 tttttaaatt tcagtgtgac cccataaagt gccggttccg tgatacctgc cagcaaagct
    26701 gaaatccccg cggcaagggc aacttgacgt gtttgtttct gctttgtttt aaaggcaaca
    26761 gccaaagatg cggctccttg agccaaatta gaagccaaca ttgctggtaa aatcaagaca
    26821 tctggtgttg cgaccgaagc ggccaaaaag attggtgcaa aagcccagtg catccccgtc
    26881 atgacaacaa gcggcataat cgctcccaaa atggcaagtg ctagccacgg agccacatga
    26941 taaatagcga gcatggtatt agataaccct tgaccaataa tcacaccaag aggacctaca
    27001 accactaaag ccaaaaagcc agaaatcaaa atgattaagg ttggctgtaa gaagcttttc
    27061 atcacgcttg gcaccaagcg attgacccat ttttcaatgt attgcatcaa gtaaaccatc
    27121 atcaaaatgg gaataacaga tgagccatag ctagcaggag tgactggtgc tccaaataaa
    27181 gccaatggtt taccttctgc taccattgca acaaaggcag gatgcaataa aatccctgcg
    27241 atcgtcgctg ctaaaacagg tgtcacctta aagcgcgccg ctgctgaata ggcaatcatg
    27301 acaggcataa aataataagc cgcatcgcca aagaagttaa taaaggcaac ggtttgagag
    27361 tccgcactcg ctaagccaag catagtaagc aagattccca ccactttgag cattccacca
    27421 ccaagaaggg ctggaatcag cggtgtaatc acgccagcaa tggtttcaat caagcgctca
    27481 aggatacttc ctttcgcttt tgaagaatga tcttcatctt gattgtcaaa atgccctagg
    27541 cttaaaaagg cttggtaata attattgaca tcattgccca agataatttg gtactggccg
    27601 tttttgcgca tcacgccaat cacatttgaa atggctttga cttgctgatc tttaactttc
    27661 tcatcatttt tcagtactaa gcgtagacgt gttacacagt gtgtcacacg ttgaatattt
    27721 gttttgccac caaccgccgc taaaatagcc ttggcagttt cttgatacgt catattaagt
    27781 ctcctttaaa tgtttcacta aacgtttaac atgaaccgtc aaatacaaaa gttcgcttga
    27841 attaaggtgg tagttgtacc gcttttttat ctcctcacta atatctaaga cgcaccggta
    27901 ttctttaggg tatttcgttt tcaccactaa aagcagttcc gcatcatcat catcgtaaga
    27961 catctcggat aacacacgtt gagcaaataa tttaatatgg gtcataaaac ggtaataatc
    28021 gatggatgtg tcatccaatt ctgttttgaa gtctgttttg attttttgct caatataaga
    28081 aacaatctcc gtcaggcgat gtggctcctt aaaaggagtg tccaaactag cattgacaaa
    28141 atgcatggca ataaaagctg cttcatcaat agctagagtg actcctagat tacgctcaat
    28201 tagctctaag gcttttaccc ctagactata ttcatcagga taatagcgtt gaatttccca
    28261 ccgtagtggg ttatgaatca acattccttg ctcatgcctt tcaatagcag agtgaatatg
    28321 atccgttaaa ttaatataga gaatttcatc taaggttttg cctaatttaa ttttacctag
    28381 attgataatt ctctctgagc aagcaacaac ttcttgtggc accgtaataa ataactctgt
    28441 gaagcgattc atattgtcac tattttttaa aacaaatgat gtttcgatag cattaagctc
    28501 aatactatct ccaacttttt ttccaaaggc aatccctttt cccatcaata aaatatctaa
    28561 tccttgatgg ttggtcgaaa tcgccgcatt atggtttaaa acgcgtttaa tcaacataaa
    28621 agtcctagtc ctttagtatc acaataaaaa atgacctatc caaaagctcg ctaaaaagca
    28681 cttttcgaat aggtccctgc tcacaaaact gtgataacat cctttaatat tctgattgtt
    28741 atgtctctag cctgcttacc tgaagtaatc acatctgaga acgctttaat gttatcatct
    28801 ctttaagatt ctgtcaagcg ttttcaaaaa attctctgaa agagcaacta ttgttattcg
    28861 tatctattga tttagcaaaa aagagtttct gacaatttta agattatatg atacaataac
    28921 aatcgattag ataaaggagt tatcatgtca catcatcaac aaaccgtttc aaaacaaaca
    28981 attatggcga ttatcgccat agcactcatt ggtttttcag gaattttgtc tgaaaccagt
    29041 atgaatgtca ccttcccgac actgatgtca gtctatcagt tgcccttaaa tagcttgcaa
    29101 tggatgacga ccatttattt actagcagtg gcgattatga tgaccacttc ggctacactg
    29161 aaaaaaaatg tgcgggaaag acccctcttt tttatggcca caggtctttt tacatttggc
    29221 accatcttgg ccgttctgac ccagtccttt gcgatcatgt tgctagcccg catttttcaa
    29281 ggcattggta ctggtctggt aatgcctcag atgtttaata ttattttaga gcgtgtccca
    29341 atgcataagg taggtctatt tatgggattt gctggtctta ttattagctt agcacctgct
    29401 tttgggccta cttatggggg ctttatgatt agccatttta gttggcaatg gatttttatc
    29461 tgtatactcc ctgtaccact gattgcaggt attctagctt attattacct cgaagattct
    29521 ccagtaagcg aaaaagtacc ctttgactgg ttggcattta ttgcactatc gattagctta
    29581 acttctgcct tattagctat tactagtcta gaaaacggaa gtgttaattt gtattactta
    29641 gggcttttta ttctcagctt tgtcctcttt ctctacaaga atctcacagc taagcaaccc
    29701 tttcttgata ttcgcattct caaaattccc tctctaacct ttggcctgat tccctttttt
    29761 gtcttccagc tgattaattt aggcataaat tttctaacgc caaactttat tgtcatggaa
    29821 aagattgcta atagttctca agctggtatg gtgttactac ctggtacctt actcggagct
    29881 ctactagcac ctgcttttgg taaactttat gatcaaaaag gagcaagact ttcgctttat
    29941 ttaggaaatg ccttatttag tttatcattg attattatga cacttcaaac aagacatttt
    30001 atgcttttac cattcactct tttatatatt ttattcacgt ttgggcgtaa catgggcttt
    30061 aataatagct tagccacggc tattcgagaa ttgcctgccg agaaaaatgc cgatgccacg
    30121 gccatttttc agatgatgca gcaatttgct ggcgctctag gaactgctat ggcatcactg
    30181 atagcaaata gtcagccaga attcacaagc ggtgtccagt ctgtctacct tctctttact
    30241 atttttgctc tacttgattt tatctttttc tttgctatgt tttaccattt agggaaaaaa
    30301 ggattagcct aagctgactt acttaaaaac cagcctcgtt ctgttgaaca agactggttt
    30361 ttttcttata aaataccttc taaaagacct ttcataaagt cttctgagtg gaattctcca
    30421 atatcatcca ctttttcacc aaatccgatg aacttgactg gaatgtctaa ttcttgacga
    30481 atggctagga ccaccccacc ttttgcagtc ccatcaattt tcgttaaaat taagcctgtt
    30541 aaaggtgtta tttttgaaaa ttccttggct tggctaagcg cattttgacc tgttgacgca
    30601 tctaaggcca aaagcgtttc atgaggggca tctggtagaa cgcgcttaat gatacgaccc
    30661 attttttcca gctctgccat gagattttct ttgttctgca ggcgaccagc cgtatcaatc
    30721 agaagaatat ctacttcttt tgccacagct ttttccatcc cgtcaaaaac aacagacgct
    30781 ggatcagcct tttcagggcc agtaatgact ggcacatcta ctcggcgtcc ccattcgact
    30841 agctgagcca cagcccctgc tcggaaggta tctgctgcca ccaacatgac ttttttacct
    30901 tcttgtttgt aacggtaagc cagcttcccg attgaagtcg ttttaccaac cccgttaaca
    30961 cctacaaaaa gcataaccgt caagccatct tgataattaa tggcttcatt ataacgcccg
    31021 tctttttcat agatatctac caatttttcc acaatcacac gtttcaaggc atctggtttt
    31081 ttcgcatttt ccagtttggc ttcataacgc aactcctctg tcaaagttgt cgccacatgt
    31141 acaccgacat ctgataagat cagcatttct tccaagtctt caaagaattc ttcatccact
    31201 cgcctgaaat tggcaaagaa actgttcaga cgagctgaga agccagtccg cgtttttttc
    31261 aagctacgct tgtatttttc ttgatctgtc tcaggaatgg tatcgtaggt tgccttgttt
    31321 tgagaagctt ctgctgaggt agaggcctga ttttcttgtg gaacctcttc tggcatcact
    31381 ggaaccgttg ccgctgcttt ttcttgaagg cttttttcaa gagcagcctt acgacgatag
    31441 tagtcttcca taacctgttg gctactggat tgctcttttg aagtgtctac tgcttcttca
    31501 ttcgccgaat catttgaggc atcagcttgg gcttgttttg ttggaaactg ttccacaact
    31561 ggctggtcaa caaggtcttt tggttctgat gccgtagatt gactaagttc acttacctta
    31621 aggtctgttt tgtcggcagc aaacttattg gtatcttctg atggatgatt actattgtca
    31681 cctgtttctt cctcaacctg tgcgtttact gaagctgctt cgggaccatt ttccaccgaa
    31741 cctgcgccct ctgaagaaac gtcctcttgt tgaaccgcct caatcttgtc ttgctcattg
    31801 gctttttcag aaagctcctc tttctgagtt gtttctgtca aaagattttc ttctaacttt
    31861 tcctcagcta ccttcggggt ttcttttttc ccaaataaac gatcaaataa tcccattaac
    31921 tctcctcttc taaaataaat gtcttcacag cttctgcaac tccagactca tcattggtca
    31981 aggtggtcac ggcatcggca acggctttag ctcctgaaac accattagcc atagctactc
    32041 caagtcctgc ccattctaac atcgcaaagt cgttagcttc gtctcccata gccatgacat
    32101 gtctagcgtc aaggccaagg tgctggcaaa gcaagtttaa tccaaaagct ttatcaatgc
    32161 cttttggcat gatttcaaaa ataatatctc gtgatttaaa ggcttcaaaa tcctcaaata
    32221 agcttgggga tagctttata atctgctgat ccaaaaagtc tggatcggtg actgtcacaa
    32281 ttttgttata gataatgtct tttggtagtt ccgctacaga tgtcacctca ataaaggtca
    32341 acagtgggtt agctagatgg tactgcgaat gcctaccgtc cttacttgga atgctataca
    32401 catccccacc actgataata tctgttggta agccaaccgc ctctaaagct tgctgaatct
    32461 ggcaaacctg gtcaaaactg agagagctct tatccaaaac ctcccctgta tttcgctgaa
    32521 ccaaaccccc attaaaggta atactgtagt catcgtggtc aagcaagtcc aactcttcta
    32581 gcaagttacc gatggccttt agagggcgac ctgtggtaat aaccacctta accccttttt
    32641 ctctaaccgc tgctaaggct tttttattgg catctgtgac aattttttca gtgttgtaga
    32701 gggtaccgtc taaatcaagc gccaaaattc taatattcat gagttacact agtcctttta
    32761 aatacgttag tactgctccg tcattacagt ggccaatgac ttggtctgaa atcactttga
    32821 tttcaggtct tgcattttcc gtagcaatag ccctaccagc aaactccaac atctggtaat
    32881 cattaaaatt atccccaaaa gcaatcgttt ctgctttctt aatgcccaag gcttgacaaa
    32941 gatgctccat accaaagccc ttattcacct cttttaagat aatatcaatg gaatcaaagc
    33001 cggtggtcac tgcagtggca taagggaggg cttgattcaa ccaatcgctt ccttctaaga
    33061 cggtatggcc tgtgaagttg gtagaaactt taaaaatggc gtcattctcc atatcttcaa
    33121 aaccattaat aaccttaaca ttagcatagt aatgttttgt tttttgaatg tactcttctg
    33181 atgcgccttt taaaatatag gctgcctttt gcccagaaaa aaccatacct gtttctacat
    33241 agtgaggatt ggctaaaatc ttttttgcaa cttcggtata ctgctctttg gtcatcatat
    33301 ctgcaaatag aatctcacca cggtattgaa ccacggaacc attttctgca ataacagcaa
    33361 tctgatccaa aaagggctca aagagctgat caatggctaa gagcgagcgg ccactcgaaa
    33421 ccgcaaataa aatgcctttt tcggctaact ttggcaagag cgcagctagt tgctcttgat
    33481 tataagtacc atcttcagct aggaaggtac catccatatc tgttgctatt agttttatca
    33541 tacaatgtct ccttttttta ctctaggggg gtgcaaacgc catttagggt gtgcactttt
    33601 taacgattta aataagcccc atcatttctg cattctgttc aatttttctt attatatcat
    33661 aaaaagcagc tttcattcca ttcgtaaaaa acagccagat tatatttcga taacctgacc
    33721 gtttttgaag tgaactgcta ctttttttat ttttataaat gaccactgga tgtatactat
    33781 aaaagtagac aaaactttgt gtgttacaat ctgttttaaa agacacaaaa acgaaaggac
    33841 aacctatgtc aacagttaaa cgctacagat gaagaattta aacaatccct tgtcaacctt
    33901 tatcaaactg gaaaaactca gtctgaactc tgtaaagact atggggtatc cgcttctgcg
    33961 cttgcaaaat ggatcaaaca gtattctcaa gtcaaactcg aagataattc tgtacttact
    34021 gccaagcaaa tacaagagct acaaaaacgt aatgcgcagc ttggagagga gaaccttatc
    34081 ctaaaaaaag caagtgccat attcatgcaa aacttaaagt aagactcctc gctgtctatc
    34141 ggttacgctt tgaacacgcc acaacaacct tgtatcgtgt tttacgtgtc aatcgctcca
    34201 cttactataa atttctaaaa cataagccct caaaaagaga attggataag caaatttata
    34261 gaaaacaaat acttgagatt tataccaaag cgaacaaaag acttggtgtg aagtctatca
    34321 aggtcattct tcaaagagac tacgacacaa aaatctctga aggaagaatt taccgtctaa
    34381 tgaagaatat ggcgctccct aaaatggcta ccgttaagcc aaaaacagct cttaaaagga
    34441 ctcaaaaaac gtatcctcaa aacttactca accagaaatt taatcctgac aaaccaaatc
    34501 aagtatggtc tactgacttc acctatattt ctattggata taagaaatat gtctatctct
    34561 gcgcaatact tgatctctat tctagaaaat gtattgcttg gaaattgagt catcatatgg
    34621 atgcaaagtt agcatgtgac actctagaat tagctcttaa taaaagaaag attgaaggaa
    34681 cacttctctt tcattccgac caagggtcac aatttaaggc caggaaattg agaaaaataa
    34741 ttgatgacaa cactatcatg cattcttttt ctaaacctgg atatccttat gataatgccg
    34801 taactgaagc atttttcaag tatttaaagc atagacaaat caaccgaaaa aagtatcaaa
    34861 atatcaaaca ggttcaatta gactgctttg aatacattga gaatttttat aacaattaca
    34921 acccacatac ggctaatcta ggactaaccc ctaatcagaa agaagaaaat tagtttaacg
    34981 taataaaata acacggtttt ctgtctactt atttgacatt agtccaaaat acatcctaat
    35041 ggtgtcgctt tttttatttc actagacatt cgttctagtt taggatataa gaaggtctca
    35101 aatttttttc aggatgttta ttccaaacat ccaatcacct ttctatataa ctgttcattt
    35161 agtggtatag acaaacagaa atactccgtt tctagtttca tagaagacgg agtatttttt
    35221 agtagagacg tctggattga tagatagttg gtatatagct catccctact aggctttcat
    35281 tataggctat ggtgggcttc gttgacaaca atatgtgatt attattctaa atgacagtat
    35341 acatcaacta tcaagtatgc ttttaatttt attttttaaa gctacagatg aaaatctgta
    35401 ttccatactt ccatctaatc gaacaataat ataatgatgt ctcgaatata attcatgttt
    35461 aaaaaacttt ttgatttttt tataaggaaa ctcaaaaaca gaacaatgat acccacttat
    35521 tttatttgct aattcaagac aattcttata gattttcaca tctatttttt caactaatat
    35581 cattattcta tcttcaattt catactcaat ctcttgtgat aaaacagtgg ttcctattcc
    35641 catgcaaact cctaatacgt ttactttatt aaatttagaa accatatcat caattctacc
    35701 accatcagca atatcaaa
//
LOCUS       DAUCXI010000018        35291 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.018, whole genome shotgun sequence.
ACCESSION   DAUCXI010000018 DAUCXI010000000
VERSION     DAUCXI010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35291
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.018"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            24..452
                     /locus_tag="VGY43_000906"
     CDS             24..452
                     /locus_tag="VGY43_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEQ4302104.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVETKLSE
                     YAKDEIDIIDQYVAKNDDDKWITDDKGNPKIEDTSKLAELNDFLDELASEPIVIKGGE
                     YSKRFIDFLEYLVESEDEFTSEEIVLIDNILEQFEESKGE"
     gene            455..1066
                     /locus_tag="VGY43_000907"
     CDS             455..1066
                     /locus_tag="VGY43_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEQ4302105.1"
                     /translation="MRNWKVIGKYPQYDSTGAVASTHIIITAEDGSVISQPIKQDLTS
                     TNDTEIIKATLEEFKKSEYVEIAMSEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKKGEYQAYDVFTVVDDKHEEQ
                     AGEGNLVFVHVNDSFTYETQTLEDLESEDKVTVIKYADLVKQD"
     gene            1076..1531
                     /locus_tag="VGY43_000908"
     CDS             1076..1531
                     /locus_tag="VGY43_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEQ4302106.1"
                     /translation="MIIDLTSLIHLFGDLVRTVEIHVFTLFVCFDIITGLTKGITNKR
                     ANSTKGLSGIIKHFLVVLLVYTVYPYLILLGAKPLAVAFVLFFIACYGISIVENWGQL
                     GLPMPSFVRSFFEKLKRDTDQFDIATIKIDKTGVKLEAPQVDLKQKEEE"
     gene            1649..2401
                     /locus_tag="VGY43_000909"
     CDS             1649..2401
                     /locus_tag="VGY43_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEQ4302107.1"
                     /translation="MATLDEVLSFAKGLADAGQGVDLDNVYGTQCVDLPNWITTKYFS
                     IALWGNAIDLLDSAAAQGMEVVYNAPGVNPRAGAIFVMVTYAHGYGHTGLVIVTSDGY
                     VLHNIEQNVDGNADALYIGGPARYVDRPFEDGTGYILGWFYPPYDSTPAAVTEPSAPV
                     VAQSDGTYVANPETGTFTVRVAALNVRSAPRLDAEIVATYGENMEFNYDGWIDSDGYI
                     WVTYISVTGVRRYVSVGNSENGRRVTNFGTFR"
     gene            complement(2470..3177)
                     /gene="speC"
                     /locus_tag="VGY43_000910"
     CDS             complement(2470..3177)
                     /gene="speC"
                     /locus_tag="VGY43_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021733756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeC"
                     /protein_id="HEQ4302108.1"
                     /translation="MKKINIIKIVFIITVILISTISPIIKSDSKKDISNVKSDLLYAY
                     TITPYDYKDCRVNFSTTHTLNIDTQKYRGKDYYISSEMSYEASQKFKRDDHVDVFGLF
                     YILNSHTGEYIYGGITPAQNNKVNHKLLGNLFISGESQQNLNNKIILEKDIVTFQEID
                     FKIRKYLMDNYKIYDATSPYVSGRIEIGTKDGKHEQIDLFDSPNEGTRSDIFAKYKDN
                     RIINMKNFSHFDIYLEK"
     gene            complement(3288..4046)
                     /gene="mf2"
                     /locus_tag="VGY43_000911"
     CDS             complement(3288..4046)
                     /gene="mf2"
                     /locus_tag="VGY43_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNase Mf2"
                     /protein_id="HEQ4302109.1"
                     /translation="MKLSKQKASLLTAVLLLLSLSITTITVDAAKVRTYPNVSHANTH
                     YKNTASSKLLPFTANYQLQLGELDNLNRATFSHIQLQDRHETKDVRTKINYDPVGWHN
                     YQFPYGDGSKSSWVMNRGHLVGYQFCGLNDEPRNLVTMTAWLNTGAYSGANDSNPEGM
                     LYYENRLDSWLALHPDFWLDYKVTPIYSGNEVVPRQIELQYVGIDSSGELLTIRLNSN
                     KESIDENGVTTVILENSAPNINLDYLNGTATPKN"
     gene            4286..4468
                     /locus_tag="VGY43_000912"
     CDS             4286..4468
                     /locus_tag="VGY43_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEQ4302110.1"
                     /translation="MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPNEKIKNGE
                     IVTDEKVEEVLVELSR"
     gene            5000..6862
                     /gene="cadA"
                     /locus_tag="VGY43_000913"
     CDS             5000..6862
                     /gene="cadA"
                     /locus_tag="VGY43_000913"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEQ4302111.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQLASAIFITA
                     FLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAEAASTHPISKAFLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKSFILEMVPDLSAFEETIQVEESQGKTLIFVSRDNQLVAYYALLDDIKL
                     ESKRAIEALHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     gene            complement(7162..8097)
                     /locus_tag="VGY43_000914"
     CDS             complement(7162..8097)
                     /locus_tag="VGY43_000914"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEQ4302112.1"
                     /translation="MVSTATQISHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLKVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNVPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIEDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGVKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            8336..9031
                     /locus_tag="VGY43_000915"
     CDS             8336..9031
                     /locus_tag="VGY43_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEQ4302113.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            9138..9659
                     /locus_tag="VGY43_000916"
     CDS             9138..9659
                     /locus_tag="VGY43_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEQ4302114.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            9820..10362
                     /locus_tag="VGY43_000917"
     CDS             9820..10362
                     /locus_tag="VGY43_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302115.1"
                     /translation="MIKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            10486..11265
                     /locus_tag="VGY43_000918"
     CDS             10486..11265
                     /locus_tag="VGY43_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEQ4302116.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFVTNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            12054..12650
                     /gene="recR"
                     /locus_tag="VGY43_000919"
     CDS             12054..12650
                     /gene="recR"
                     /locus_tag="VGY43_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEQ4302117.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYRG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            12751..13797
                     /locus_tag="VGY43_000920"
     CDS             12751..13797
                     /locus_tag="VGY43_000920"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEQ4302118.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIRTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEIFDQRESHLI"
     gene            13996..15363
                     /locus_tag="VGY43_000921"
     CDS             13996..15363
                     /locus_tag="VGY43_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEQ4302119.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELPGKLHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMISAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIHLLSEIARPRIAVLTLVGEAHLEYFGSRDKIAQGKMQIVDGMDSNGILIAP
                     GDSIIDPYLPENQMVIRFGDHQELNVTDIREEKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVADEDIIEALESVQLTANRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGPDSVALHSQLIKQLSPDRIDQLVFYGDDIQE
                     LAQLAHEFYPEGHVQFFQKNQQEDQFEDMVRQVQQLLAPSDQILLKGSNSMGLAKLVN
                     HLVEN"
     gene            15467..16162
                     /locus_tag="VGY43_000922"
     CDS             15467..16162
                     /locus_tag="VGY43_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEQ4302120.1"
                     /translation="MDFFAIDPIGLPHTSLIFYLSSLLIALLLVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYLGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLALAFSKEK"
     gene            16410..17954
                     /locus_tag="VGY43_000923"
     CDS             16410..17954
                     /locus_tag="VGY43_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEQ4302121.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGVVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            18261..19880
                     /locus_tag="VGY43_000924"
     CDS             18261..19880
                     /locus_tag="VGY43_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ4302122.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGSYRGDRNRDERDGDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            20007..22007
                     /locus_tag="VGY43_000925"
     CDS             20007..22007
                     /locus_tag="VGY43_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEQ4302123.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWL
                     IIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYL
                     IKKGTRPILAHLAMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKR
                     PKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA"
     gene            complement(22031..22309)
                     /locus_tag="VGY43_000926"
     CDS             complement(22031..22309)
                     /locus_tag="VGY43_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEQ4302124.1"
                     /translation="MTTKKAYMYVLECVDKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(22299..23153)
                     /locus_tag="VGY43_000927"
     CDS             complement(22299..23153)
                     /locus_tag="VGY43_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEQ4302125.1"
                     /translation="MKADFSKVKITLQTFTSSLFYVKITGMIKAILKEGERIDQLFSS
                     DVGIIQNKDVFSYSIDSVLLSRFPKMPSKGLIVDLCSGNGAVGLFASTRTKAAIVEVE
                     LQERLADMGQRSIQLNQLEDQVTMICDDLKNLLNHVPRSGVDLMLCNPPYFKSHESSK
                     KNVSEHYLLARHEVTTNLEEICQVARHALKSNGRLAMVHRPDRFLEIIDSLRANGLAP
                     KRVQFVYPKLGKSANMLLIEAIKDGSIEGMTILPPLVVHKENGEYTDHIFEIYFGVAS
                     KGKPNHDH"
     gene            23193..23933
                     /locus_tag="VGY43_000928"
     CDS             23193..23933
                     /locus_tag="VGY43_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEQ4302126.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKMAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRMDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTMLFSYIASFVWNPDKHRH"
     gene            24132..24794
                     /locus_tag="VGY43_000929"
     CDS             24132..24794
                     /locus_tag="VGY43_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEQ4302127.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKEIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            24775..27018
                     /locus_tag="VGY43_000930"
     CDS             24775..27018
                     /locus_tag="VGY43_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEQ4302128.1"
                     /translation="MTFSWTKLMPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICL
                     LVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLEIQPVQITSVALVPDSIRINGDQ
                     LAVLGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVMHAKVTLEKAEEVRNFKGFNYQT
                     FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLL
                     FGYLDKSFGEMTDYYSQLGIIHLFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELP
                     FACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLT
                     FSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTALLSYLF
                     DLFILPLLCLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
                     VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSILVREWTGK
                     NLLIDVGGRPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHADTDHMGD
                     IEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPW
                     QLGDGKNNDSLVLYGRLLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTS
                     SSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDRQITYYRTDTQGAIRLTGRTS
                     WHLETVR"
     gene            27089..28129
                     /locus_tag="VGY43_000931"
     CDS             27089..28129
                     /locus_tag="VGY43_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEQ4302129.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMEQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEASPLKEAELRTYFQKYSHQ
                     LGLGFESGAFEQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLRGKIDAARDLIHDLRLSGEDDIKLIAIMLGQFRLFLQLTILARDVKNEQQL
                     VISLSDILGRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            28226..28831
                     /locus_tag="VGY43_000932"
     CDS             28226..28831
                     /locus_tag="VGY43_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEQ4302130.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSELYQAAK"
     gene            28998..29221
                     /locus_tag="VGY43_000933"
                     /pseudo
     CDS             28998..29221
                     /locus_tag="VGY43_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            29209..29436
                     /locus_tag="VGY43_000934"
     CDS             29209..29436
                     /locus_tag="VGY43_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302131.1"
                     /translation="MDALGLYYDDNHLSLVNTVKVYLKEFGIGESQIAFSYKDLNSGR
                     TAAMNDHQPMIAGSTYKLPLNMLVVDKANYP"
     gene            29433..30010
                     /locus_tag="VGY43_000935"
                     /pseudo
     CDS             29433..30010
                     /locus_tag="VGY43_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S11"
     gene            complement(30124..31344)
                     /locus_tag="VGY43_000936"
     CDS             complement(30124..31344)
                     /locus_tag="VGY43_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEQ4302132.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKLYQDLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSTLIQAYYVNLEHIPYSRFNRKIHQLRYLISTQQMEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(31351..32379)
                     /gene="queA"
                     /locus_tag="VGY43_000937"
     CDS             complement(31351..32379)
                     /gene="queA"
                     /locus_tag="VGY43_000937"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEQ4302133.1"
                     /translation="MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGRLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGSKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            32581..33285
                     /gene="nagB"
                     /locus_tag="VGY43_000938"
     CDS             32581..33285
                     /gene="nagB"
                     /locus_tag="VGY43_000938"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEQ4302134.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDI
                     EAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIEANSRF
                     FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADAIKGMVFGPITEDLPASILQKH
                     DHVIVIVDEAAASQLD"
     gene            33404..34120
                     /locus_tag="VGY43_000939"
     CDS             33404..34120
                     /locus_tag="VGY43_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ4302135.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPSHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTASERQLIKTYLD"
     gene            34417..>35291
                     /locus_tag="VGY43_000940"
     CDS             34417..>35291
                     /locus_tag="VGY43_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEQ4302136.1"
                     /translation="MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESF"
BASE COUNT        10752 a         6167 c         7264 g        11108 t
ORIGIN      
        1 attaataact tataggagaa acaatggatt taacgcttaa aaacaaagat ttaaacacac
       61 tatatagtgt actagacaaa atcaaagtca cgaacatgcg agcaaatcgt gggcgcgcta
      121 agctgcttgc aaaagtagag actaagctaa gcgagtatgc caaagatgag atcgatatta
      181 ttgatcaata tgtcgctaaa aatgatgatg acaagtggat tacagatgac aaaggtaatc
      241 caaaaattga ggacacctca aagttagctg agcttaacga ctttttagac gagttagcaa
      301 gcgagcctat cgtcatcaaa ggtggcgagt actctaagcg ctttatcgat tttttggaat
      361 atttagtcga atctgaagat gagtttacat cagaggaaat cgtcttaatt gataatattt
      421 tggaacaatt tgaagaaagt aaaggagaat aattatgcgc aattggaaag taatagggaa
      481 atatccacaa tatgacagca caggagcagt cgcaagtaca cacatcatta tcacagcaga
      541 agatggctca gtcatctctc aaccaatcaa gcaggactta acctcaacta atgacacaga
      601 gattatcaaa gctactttgg aagaatttaa aaaatccgaa tatgtcgaaa tcgctatgag
      661 cgaagcagtc caaaaagttg atgacttgga aaaaatctca caagaaaccg ctaagactgc
      721 taaaacagcc caaacagccg ctggactagc taaggtgtcc gcagagcgta cacagcggat
      781 gattaacttg caaaccatcc acgtattgac aagtggtggg aaagttgaac ccgatatcta
      841 caaaggtatg ttagagctta ttgagccagc caaaaaaggt gagtatcaag cctatgatgt
      901 ctttacggtg gtcgacgata aacacgaaga gcaagctggc gaaggcaact tagtctttgt
      961 ccatgtcaac gactcgttta cttatgagac acagacctta gaggacttag aatcagagga
     1021 taaagtcaca gtcattaagt atgcggactt agttaagcag gattgaggtg gttagatgat
     1081 tattgattta acaagtctta ttcacctttt cggggattta gttcgtaccg tcgaaatcca
     1141 cgtttttacg ctttttgtct gttttgacat tattacagga ctgacaaaag gtattactaa
     1201 taagagagca aacagtacaa aagggctatc tggcattatt aaacactttt tagttgtgtt
     1261 gttagtctat actgtctatc cttacctaat cttgctcgga gctaagcctt tagcagtcgc
     1321 ctttgtccta ttttttatcg cctgttatgg tatttcaatc gtagaaaatt ggggacaact
     1381 aggtttgcca atgccaagtt ttgtcagatc atttttcgaa aagctcaaac gtgatacaga
     1441 ccagtttgat attgcgacaa tcaaaattga taaaacaggt gttaaactcg aggcgccaca
     1501 agttgattta aaacaaaaag aagaggagta gcatgagaca agcagtcaca cgattagcat
     1561 tagttatagc aatcgcaata ctgtatgtgc cattatctgt gattgctttg attttaagcc
     1621 cattttttga agaaaggaag taactgatat ggcaacttta gacgaagtct tgtcttttgc
     1681 aaaaggatta gcggatgctg gccaaggagt tgatcttgat aatgtttacg gtacgcagtg
     1741 cgtggacttg ccaaactgga tcacgacaaa atattttagc attgcccttt ggggcaatgc
     1801 tattgactta ctagatagtg cagctgccca aggaatggaa gtggtctata atgctcctgg
     1861 agttaatcca cgagctgggg ctatctttgt gatggtgacc tatgctcatg gttacggtca
     1921 tactggatta gttattgtga cgtcagacgg atatgttctg cataacatcg agcaaaacgt
     1981 ggatggtaat gctgacgccc tttacatcgg tggtccagct cgatatgttg accgcccatt
     2041 tgaagatggc actggatata ttttgggttg gttttaccct ccttacgata gtacgccagc
     2101 agcagtgaca gagccaagcg ctccagtggt tgcacagtca gatggtactt atgtagctaa
     2161 ccctgaaaca ggtactttta ctgttcgtgt tgctgcttta aacgtccgtt ctgcgcctcg
     2221 attagacgca gaaattgtgg caacttatgg cgaaaacatg gaatttaact atgatggttg
     2281 gattgactca gatggttata tttgggtgac atacatcagt gttactggtg ttagacgata
     2341 tgtgtccgtc ggaaattccg aaaacggacg acgtgtgacc aactttggta cttttagata
     2401 ggaggtaaag ctccgagata agacaaaacc gctcagataa tttctgggcg gttttttgtg
     2461 tatgatgaat tatttttcaa gataaatatc gaaatgacta aagttcttca tattgataat
     2521 tctattatct ttatattttg caaaaatatc tgatctagtc ccttcatttg gtgagtcaaa
     2581 taagtctatt tgctcatgtt tcccatcttt tgtgccaatt tcgattctgc cgcttacata
     2641 aggagaagta gcgtcataaa ttttataatt atccataagg tattttctga ttttaaagtc
     2701 aatttcctgg aaagttacga tatctttttc tagaataatt ttgttattta agttctgttg
     2761 agattctccc gaaataaata gatttcccaa taatttatga tttactttat tattttgagc
     2821 aggcgtaatt cctccataga tgtactcacc ggtgtgagaa ttaagaatat aaaataatcc
     2881 aaaaacatct acatgatcat ctcgtttaaa tttttgagag gcctcataag acatttcgga
     2941 actaatataa tagtctttcc ctctatattt ttgagtatca atgtttaatg tgtgtgtcgt
     3001 tgaaaaattt accctgcaat ctttataatc ataaggagtt atagtgtatg cataaagtaa
     3061 atcactttta acattcgaaa tgtctttctt agagtcactt ttgatgatag gtgaaatagt
     3121 agaaatcagt atgactgtaa ttatgaaaac tattttgatg atgttaatct ttttcatttt
     3181 ttctccttaa ttaaatgtat tactcgtacg agaatacatg aaatagcagt aagtagttaa
     3241 aaatcagatt tctgtttatt tagaaatttt ataaatgtat ttatatttta gtttttagga
     3301 gtggcagttc catttaaata gtcaaggttg atatttggag cagagttttc taagattact
     3361 gtagtaacac cattttcatc aatactttct ttattactat ttagccttat agtaagcaac
     3421 tcaccagatg aatcaattcc aacatactgt aattcaattt gtcgaggcac tacttcattg
     3481 ccactatata taggagtgac tttataatct agccaaaagt cagggtgaag tgcaagccaa
     3541 gaatctaaac ggttttcata gtataacatc ccttcaggat tgctgtcatt tgctcctgaa
     3601 taagcacctg tgtttagcca ggctgtcatt gtcactaaat ttcttggttc atcgtttaat
     3661 ccacaaaatt gatatccgac tagatgccca cgattcatta cccatgaaga ttttgagcca
     3721 tctccgtatg gaaattgata gttatgccat cccacagggt cataatttat tttagtgcgt
     3781 acatctttag tttcgtgtct atcttgcagt tggatatgtg aaaaggtagc gcggttaagg
     3841 ttatccaact caccaagttg taactgataa ttagcagtaa aaggtaagag cttactagaa
     3901 gcagtatttt tataatgtgt gtttgcatgg gatacattcg gataagttcg taccttagct
     3961 gcgtcaacag ttattgtcgt tatagaaaga gaaagtaaca gtaaaacagc ggtaagcaaa
     4021 cttgcctttt gtttagataa tttcatgata acacctaaac ctttccattt ttagctttta
     4081 gagtggatca aatattgcac ttttctagtt aattatatca ctttaaatta aaaaaactta
     4141 aaattaataa aattaattta tcaataatat tacgctaaaa tttctttttg tttaataaaa
     4201 tagaagttat taaattttaa taagttttaa atttaagtgt actatattct cgtaaaatac
     4261 gaataataag ataaggaggt gctttatgct aacatacgac gaatttaaac aagcaattga
     4321 caatggatat atcacagcag acacagtaat gatcgtgcgc aagaacggac agatttttga
     4381 ttatgtgttg ccgaatgaga agataaagaa tggagaaatt gtgacagacg aaaaagtgga
     4441 agaggtgctg gtggagcttt cgagataagt attttctttg ccccctgaga agtagtttta
     4501 ttaaaggggt aaataggggg cataagttta aaacttacat agttgattcg aagcaattat
     4561 ataaagtttc gttattttgt agctttataa aatcaaagtt tattatatta tatgtgcaca
     4621 atattaagta atctttaaaa gacgctgtta aataattcgt ctagaaaaat cttgttgcta
     4681 tcgatgttta ttgatagcga caaggttctt tttttatatt tggggcataa agttagtagt
     4741 tttctcttca gttaagctaa gttctaatgc atgcactcta taatggtcag tcatccttct
     4801 attagtatat catttccgca ggtaggggga gtttttttca tatttgcaaa tagttgaagt
     4861 taggattttt gaaagcaaaa ggtaagttta aaaaagttta tttagaatgt ttctaaatta
     4921 cttgacttat ttatttagaa ttattataat taatatatct taaggattga gataactttt
     4981 aattgcgagg gaactaaaaa tgacaatcag acaatggatg gcagaccatc ttcatttaat
     5041 ggagacttta gcgtgtttgg tattaataat aattggccta gcctttttac actcatttcc
     5101 acaactggct tccgctattt tcattacagc cttcttgatt ggaggatatg cgtctgcaaa
     5161 aacgggtata ttggatttgg tgaagaacaa acacttgtca gtggatattt tgatgatttt
     5221 ggcagctatc ggtgctggaa ttatcggcta ttggctggag ggtgctctgc ttatttttat
     5281 cttttcgttg tccaatacgc ttgaagaaat ggccatggaa aaaagtaagg atgctatttc
     5341 agccttgatg tccttaacgc cagatacagc tcgtcaatac caagaagatg gccatatttt
     5401 agaagttgag accagatcct tgagtgttgg tgatcgttta caagttcgta aaggcgaagc
     5461 tgttccaatt gacgggcagt tgcttagtcc ttttggtcaa tttgatgaat ctatggtcac
     5521 tggtgagcct atcactgttg ataaggcaga aggccaggat ctgattgggg gaaccattaa
     5581 ccaaggacaa accatagata tgttggttac tattgaaaat gacgatactc tctttgccaa
     5641 gattattaat ctggtagaat ctgcccaaga aaagaaaagc aaaaccgcca cctttatcga
     5701 aagcttagaa gatggttatg tcaaatttgt gctcgtcctt attcctgcct ttatcctctt
     5761 tagccacttt gtgctttctt ggacttggtt ggctgctttt taccgaggga tgattctctt
     5821 aacagtagct tcaccatgtg ccctaattgc cagttccaca cctgctagct tggctgctat
     5881 ttctcgtgca gccaggaagg gattgattat caaaggaggg gatattgtcg ataacatggg
     5941 agatattaag gctgttgtca tggataaaac gggaacgctc acccaaggaa aaccttctgt
     6001 tgtgaatgct cattatttgg aagatgagtt gctcgtgaat agactggtaa aaggagcaga
     6061 ggctgctagt acccatccta tttctaaagc ctttcttgaa tacactgaaa aattggagcc
     6121 actgaccttt gaccacttag aagaaatttc tgggaaaggt tttcagggct tctatcaagg
     6181 gcaagaatgg cgcattggga agaaatcctt tattttagag atggtgccag atctttcagc
     6241 ttttgaagaa acgattcagg tagaagaaag tcaagggaaa actcttatct ttgtttctcg
     6301 cgacaaccaa ctagtagcct actacgcttt gttagatgac atcaaattag agtcaaaacg
     6361 tgccattgaa gctcttcatg ctatgggaat caagacggtc atgttaacag gggaccaaga
     6421 acgaactgcc aattatgtgg cacaaaaact tggtattgat gaagtggtag ccaactgtat
     6481 gcctcaagat aaggtggcta agttagcaga attaaagacc aaatatggtt ttgtggccat
     6541 ggtaggagat ggtattaatg atgctcctgc ccttgctcaa gcagatgttt cttatgctat
     6601 tggatcagga acagatattg caatggaaag tgcagacagt gtgattatgg atgacttgac
     6661 tcgtattcca ttttcgattc aactttcccg caaaatgaag accattatca aacaaaatat
     6721 tgtttttgcc ttatctgtga ttaccttatt gattttagcc aatgtttttc aggtagttaa
     6781 cttgccgctt ggtgttgttg gacacgaagg ctcaacgatt ttagtgattt taaatggctt
     6841 gcgtttactt tcttttaaat aatttagaaa cttgcttgaa aacttgaaag tgtttataat
     6901 aatactaaga cttatgaaag agaaaaccgc cgtatgttta ctattatgat cattagttta
     6961 gctgtatttt caataattaa aatcattcta tttttctatt tttatcagca atttgagcgc
     7021 aagcaaaaaa gaaaagttga atcaaacaac cagcaaagac agtccaaaga aagtgacgct
     7081 gtcccttcaa aaaaattccc attttaaaaa gcttggaaag tgtacaaagt gcacatttcc
     7141 aagctttttt gactattaag gttaatcttt gtaacgtaag ttcccacgaa aatcgtctaa
     7201 gctttggtag cctttttcta ccataatcgt ttttagttcc ttagtgaccc gttcaaagat
     7261 agctggccct tcttgatgaa gggctgtccc aatttggacc atgctggcgc cacaaagaat
     7321 atgttcaaag gcatcgcgtc ctgttttaac tccccctgta ccaataatgt ggatagaagg
     7381 ttttaagcgt ttgtaaaacg catggacatt ggctagagca gtaggtttga tgtaatctcc
     7441 acctatacca ccaaagccat ttttaggctt gatgaggact tgctcatcct caatgaccag
     7501 cccatttccg atagaattga cacagttaac aaaggaaagg gggtatttat tgaaaatcgc
     7561 agccgcttga tcaaaatgca caatgtcaaa ataaggaggt aatttgatac caagaggttt
     7621 agtgtaatag gtaaagatgt tctctagaag ttgatcagtg gtttcaaaat cataagcaat
     7681 ctgtggtttt cctggaacgt tcgggcaaga aaggtttagt tccactagac cctcataatc
     7741 tgaagccatg atggctttta aaatggtttc ggtttcagta ggagatagcc cgacaacgga
     7801 gagaaaatga ggtttatgtt gcccggtttt ggcaagatca ctgacaaagt ctaagtagta
     7861 gcgaaaacca ttattaggga gtcccattga attgatggaa ccaagacgag tatctgcgta
     7921 gcgaggttct ggattacctg gacgaacttt aagcgtccct gttttggtga caaaggaagc
     7981 ggcttgagac ttttcaacct ccataagctc ttcttttgtc atgcagtaaa caccagcagc
     8041 attcatcaaa cagttatcaa aagagaaatg actaatttgt gtagcagtag aaaccattat
     8101 ttcctccata ttttagacaa attttttcta ttctaccact aggcatgaat aatagcaagc
     8161 tatttttaca aaaatgtaaa tatattactg ttattgacga acatttgaaa ttttcatgat
     8221 agtcacatta tgattttcaa taaagtcaga atagactagc ttttttgcta tattttttgt
     8281 aaaataggaa ttgtaaaaag gtagcaacct ttaaattaaa aggagatatt aactcatggt
     8341 aaaattggtt ttcgctcgcc acggtgagtc agaatggaac aaagctaacc tcttcactgg
     8401 ttgggcagat gttgatcttt cagaaaaagg gacacaacaa gcgattgatg caggtaaatt
     8461 gatcaaagaa gcaggtattg aatttgacct tgctttcact tcagtattga cacgtgctat
     8521 caaaacaact aaccttgccc ttgaaaatgc aggtcaattg tgggttccaa ctgaaaaatc
     8581 atggcgcttg aacgagcgtc actatggtgc tttgactggc aaaaacaaag ctgaagctgc
     8641 agaacaattt ggtgatgaac aagttcatat ctggcgtcgt tcttacgacg tattgccgcc
     8701 agctatggct aaagatgatg agtattcagc acacaaagac cgtcgttatg ctgatcttga
     8761 cccagccctt attccagatg ctgaaaactt aaaagtaact cttgaacgcg caatgcctta
     8821 ctgggaagaa aaaattgctc cagctcttct tgacggtaaa aacgtctttg ttggcgcaca
     8881 tggtaactca atccgcgctc ttgtgaaaca cattaaaggt ctttcagatg acgaaatcat
     8941 ggatgtggaa attccaaact tcccaccact tgtttttgaa ttagatgaaa aacttaacat
     9001 tgttaaagaa tactaccttg gtggtgaata acttaaaaac cagactttgg tctggttttt
     9061 tgattctata tcctaagaag aaagaaaacc ctgcttaaaa atatgatatg atagaaataa
     9121 aaaaggatag atagattatg aaagcagaag atcgtcgtca aaaaattatt gagtgcttaa
     9181 atagtgaaca aaaagctgta tctgctactc gtttaggtaa gttattagga gtgagtcgcc
     9241 aagtaatcgt tggagatata gctcttcttc gagctcagca gattgatatt atttcgactc
     9301 caaaaggtta tattatgtca acagcgcttt atagtcacca attttgtgca cgtattgtgt
     9361 gccaacataa tgtagaagaa actaaaaaag aattagaaat tattttagct catcaaggga
     9421 ttattacgac ggtagaggta gaacatccta tttacggtat gataacagcc cctttaaata
     9481 ttaagacaca ctctgatgta actaatttca tgtccaaact cagtcaatct aaagcagagt
     9541 tattgtcttc gttgacagaa ggactacata gtcacttaat ttcgtgtcct agtcaagaag
     9601 cctttttagc tatcaagcat gatttagaat tagcaggtat cttatacaaa ggaatataac
     9661 tatagtatat tatgccattg atggttgtta tgaataccat gctaaaatat tctattgatt
     9721 atttatcagc aacaaggtat cgtttaaaaa taccaaaaga tacaggtgtc ttgatagtta
     9781 ttggttttta aggtatacta tttttgaaaa ggagataaaa tgattaaaaa accaacacag
     9841 ctaatagctt atacctctat tttggtcgca tttgcgattt tgattccgat aatcatgcct
     9901 cttaagctta ttattggacc agcttccttt actctggcga gccatgttcc tttgtttttg
     9961 gctattttta tgtcgattcc agtagcaatt ttggtcgctc ttggtaccac attaggtttt
    10021 ttattagctg gacttccttt aattattgtt ttaagagcac tctctcattt attgtttgct
    10081 attttggcag cgtggtggtt aagtagaaaa ccacaactga tgacatcggc agtaaaatgt
    10141 tttagttttg cgtttttcat taatgtcatt catggcttgg ctgaattttt agttgtctat
    10201 attttaacag caaccacagc aacttctatg tcttattttt ggtctatgct aggcttgatt
    10261 ggcttaggtt cgcttattca tggcatattg gatttctatc ttgctttagt tctatggcgt
    10321 tttttagcaa aaaacttaaa acttcccacc ataaatgcct aagactaaaa tagagatagt
    10381 tatatgataa tgacgagccc tttcttgttg aaagggcttg cattttttag gaaaattgat
    10441 atactaaagt gtgtgtttgt gaatacagta acaaaaggag atatcatgaa aacaccagaa
    10501 cagattttag aagcaactat tcatattggg gaacataagg ttaccaaaac ttttttggct
    10561 aaatctatct taggctttat tggtggagcg atgattagcc ttggttattt actctacgtg
    10621 agaattgccg ccagtggttt agaaactttt ggtgcttttt ccagtatcgt aggagcttgt
    10681 gcttttccga ttggtctaat tattatttta atggcgggtg gagaattaat tacagggaac
    10741 atgatggctg tttctgcagc tttgttggcc aaaaaaatta agtttagcga gcttgccaag
    10801 aattggctta tcattacctt gtttaatgtg attggagctg tttttgtagc ttttgtgttt
    10861 ggtcattttc taggcttgac atcagctggt atttttaaag aagaagtgat tgaggtggcc
    10921 catgctaaaa tagcagcgag ccctttgcag gcactagtat caggaattgg ttgtaactgg
    10981 tttgttggtt tggccttgtg gctatgctat ggggcaaatg atgctgctgg taaattcctt
    11041 ggtacttggt ttcctgtcat gacctttgta gcccttggtt ttcagcatag tgtagcaaat
    11101 gcttttgtca ttcctgctgc tatttttgaa ggaggagcaa catggttgga ttttgtcact
    11161 aattttattt ttgtctatag tggtaatatt atcggtggag ccatttttgt tagtttttta
    11221 tattttaaag tttactatca tccgcaaaag agtaaaactc aatgagaaaa tattttttta
    11281 gactgagggc gtcctattct cagtcttctt tttataattt atggtaaaat aagaagcgaa
    11341 gtttaaaaaa tttagctaaa taatggttag tttattccct aaaaaatgag tattcccaaa
    11401 aaatccgtaa aaagaatttg ctatgggagt agttcccaaa ataatgtaga tcattagttg
    11461 tctttcaaaa atagccttga tagggtaaaa agtggacagt gatgcagcaa cagattcatc
    11521 aggcgtacaa actgtcttat ggtttgtgct tagagatttc ttaataatgc ttttggtaat
    11581 acacttttag tgaagaaagt gtagcatgaa agcttaaaga taaccatgag ttcgctttat
    11641 gcactattgt tgagaaaaat agcatagtca attgagtaaa catcatttct gcatggaatg
    11701 aaacaattcc tataaactta tatcataagg atggtttgcg gtttctaaaa aagtaacatg
    11761 aatcaaaaaa caaaagccaa atatcccaag gccaaggtaa caagtcgagt aaaaaagttt
    11821 ttacttggct aatccaaacg gttctgtcac gattcacgct aaaattggaa ctgctgagac
    11881 ttgtatcaca gacaattcag atcagacctt agtaacttac aacttaaatg tagtagctta
    11941 taatacaaat aacgaagata atattgcggt tgctgtacat attacgaata tatcggcaaa
    12001 gatgtgaggg cgctttatgt ggcgatatat ggaaaacaat aaaggagaac ttagtgcttt
    12061 atccaacacc cattgcaaag ttaattgaca gttactctaa acttccagga attggtatca
    12121 agacggcgac gagattagcc ttttatacta ttggaatgtc aaatgaagat gtcaatgatt
    12181 ttgctaaaaa tttattagca gctaaaagag aactgaccta ttgttcgatt tgtggaaacc
    12241 ttaccgatga cgatccttgt cacatttgca cagacacgag ccgtgatcag acgaccattc
    12301 tggtagtaga agatgctaaa gatgtttctg ccatggaaaa aatccaagag tatcgtggct
    12361 attatcatgt gcttcacggc ttgatttcgc ctatgaatgg tgtggggcca gatgacatca
    12421 accttaaaag tttaattacc cgtctaatgg atggtaaggt gagcgaagtt atcgtagcta
    12481 ccaatgccac agcagatggg gaagcaacgt ccatgtatat ttcacgtgtc ttgaaaccag
    12541 ccgggattaa ggtaactcgt ttggcaagag gtctcgcagt aggttcagat attgagtatg
    12601 ctgatgaagt aacattattg agagctattg agaatcgtac tgaactttaa tgatcatgtt
    12661 ggtgccttta ctcgcaaaga gaggttttga aaaggctaca tctttttgtt ataataaaaa
    12721 aacattcaat tcagataaga aaggttagct atgtccaaac aaacgttagt tctattatat
    12781 ggaggccgct cagcagaacg tgaagtctca gtgctttcag cagagagtgt gatgcgagca
    12841 gtcaactatg ataagttctt agtaaaaact tattttatta ctcagatggg ccaatttatc
    12901 agaactcagc aattttcaga aaagccatcg gaatcagaac gcttgatgac aaatgagacg
    12961 atagagctaa ctcaaaaaat aaaaccaagt gatatctatg aagaaggtgc agttgtattt
    13021 cctgtattac atggacctat gggagaagat ggctctatcc aaggtttctt agaagtgctt
    13081 agaatgccat atatagggac taatgtcatg tcttctagca tagctatgga taaaattact
    13141 actaaacgtg tcttagaatc aattggaatt ccacaagttg cctatactgt ttatattgac
    13201 ggacaagatt tggaggcttg tttagttgaa actttagcaa gacttacttt tcctatcttc
    13261 gtaaaaccag ctaatatggg ttcttctgtg gggatttcca aagcccaaac aaaagtagag
    13321 ttaagaaaag cgattcagtt agccctgacc tatgacagtc gtgttttgat tgaacaaggc
    13381 gtagttgcca gagaaattga agttggtctc cttggaaatg ataaggttaa atcaactcta
    13441 ccaggagaag taatcaagga cgttgatttt tacgactacc aagcaaaata tgttgacaat
    13501 aagattacga tggccattcc agcagatgta gaccagagta ttgtgacaga aatgcgttct
    13561 tatgctgaag tagcctttaa agccttaggt ggttgtgggt tgtctcgttg tgactttttc
    13621 ttgacccaag acggacaggt ttaccttaac gaattaaaca ccatgccagg ctttacccaa
    13681 tggtctatgt atccactctt atgggaaaat atgggattgg cttatccaga tttgattgaa
    13741 gagctggtga cactggcaca agaaatattt gatcagcgtg agagccatct gatttaaacc
    13801 tatgagatga ataaacattg acttggatgg aacggcaaac atcgtcaaga tgtgacgttc
    13861 gtcctttttt tgttgctctt ttaggaagaa tagtagagcc attaagggag tttgacattt
    13921 tagaaatttt tctaatgttt tgtgctataa tagataggac atcgtaaata ctagtgttct
    13981 tagaaagaaa acaaaatgaa attaacctta cacgaagtgg ctaaaatagt tgacgcccaa
    14041 aataatgtgt ctgacttaga cgacgttcct ctgcatcaca ttgaatttga tagccgaaag
    14101 attacaaaag gagacctctt tttaccctta aaaggtcaaa gggatggtca tgagtttatt
    14161 gatttagcct ttcaaaatgg agctgtcgct actttttcag aaaaagaatt gccggggaaa
    14221 cttcaccttc ttgttgaaga ctgcctaaaa gcttttcaaa agctagccca ttattatatt
    14281 gataagatgc gcgtggatgt tattgctgtg acaggctcaa atggtaaaac ttccaccaaa
    14341 gatatgatca gcgcagtcct atcaacaacc tataaaactt ataaaacgca gggaaattac
    14401 aataatgaga tcggattacc ctacaccgtt ctccacatgc ctgaagatac cgaaaaaatt
    14461 gttcttgaga tgggacaaga ccacatggga gatattcatc ttctctctga aattgcaaga
    14521 ccccgtattg ctgttttaac tctggtaggc gaagcccatt tagaatattt tgggtcacgt
    14581 gacaagattg ctcaagggaa aatgcaaatt gttgatggaa tggattcaaa tggcatttta
    14641 attgccccag gtgattcgat tatcgatcct tatcttccag aaaaccagat ggtcattcga
    14701 tttggcgacc accaagaatt gaatgttact gatattcgag aagaaaaaga tagcttaacg
    14761 tttacaacaa atgtgttagc aacacctgtg tccctacctc taccaggaaa atacaacgcg
    14821 accaatgcta tggtagcagc ctatgttggc aaattgttgg cagtagcaga tgaggatatt
    14881 atcgaggcgt tagagtctgt tcaactcact gctaatcgta cagaatggaa aaaagctgct
    14941 aatggtgctg acatcttatc agatgtttac aatgccaatc cgacagccat gcgcctgatt
    15001 ttagaaacct ttgctaacat agcaaagaac cccggtggaa aaaagattgc agtgctagct
    15061 gacatgaaag aattaggacc agattctgtt gccctacatt cgcagttaat caaacaattg
    15121 tcacctgatc gcattgacca acttgttttt tatggtgatg atattcaaga gttagcccaa
    15181 ttagcacatg agttttatcc tgaaggacat gttcagttct tccaaaaaaa tcagcaagaa
    15241 gatcagtttg aagacatggt aagacaggtg caacaattac ttgctccctc tgaccaaatt
    15301 cttttaaaag ggagtaactc aatggggctg gctaaattgg tcaatcattt agttgaaaat
    15361 taaagtgaag acttacctta gccttacttt ttagaaaaag cacagagaag ggcttgttct
    15421 ctcataaaga ttaaggtata atgaaaaaac gtagaaaggg atggttatgg atttttttgc
    15481 aattgacccc atcggactgc ctcatacctc acttatcttt tacttgtcgt cactcttgat
    15541 agcgcttttg cttgtttttt tgacttttca agcatatagg ttaaaatctt atcgttattt
    15601 tttcttgttt ttacagttat ctcaggtgat tggcttgtac acatggtacg tgttaagggg
    15661 gtttccttta gatgaagctt tgccgttgta tcattgtcgc atcgctatgt tagctatctt
    15721 ttttctacct gatcgtaata agtttaagca attatttatg gttttgggga taggtggaac
    15781 attccttgca cttttatcgc cagatcttta tccgtttaga ttatggcatg tagcaaatgt
    15841 ctcgttttat cttggtcatt atgctttgtt agtgaatggt ttgatttacc tcttgcgttt
    15901 ttacgatgcc agtcagttaa gactgctatc agtagtacgc tatttagcaa ctgttaactt
    15961 tcttcttctg ttggtcagtt tagccacgaa aggaaattat ggttttgtga tggatattcc
    16021 agtgattcat acgcgtcatt tgctacttaa ttttgtgatc gttacaagtg gcttgacttt
    16081 tatggttaaa ataaccgaat atttttacct taaatttggt gaagctcaac agctggcact
    16141 tgctttctct aaagaaaagt aggtcgttga aaaagcactt aaaatcagct ataataagaa
    16201 gagtctggaa tgatttccag gctcgatttt tttaaaaaag acactcattg atagcccaag
    16261 ataagttata ataccagttt tgaagaactt tagaggctaa tcgtatatgg agaaacccaa
    16321 tgtagcccaa ctcttttgat aaacaagtaa tacctaacga aaataactca gagaaaagct
    16381 ctgccatttt actatacaag gaaaaaagaa tgtcacttac agaagaaatt aaaaaacgcc
    16441 gtacttttgc catcatttct cacccggatg ctggtaagac gactattact gagcaactat
    16501 tatattttgg tggtgaaatt agagaagcag ggacagtaaa agggaaaaaa tcaggtacgt
    16561 ttgcaaagtc cgactggatg gatattgaaa agcaacgtgg tatctctgtt acttcatctg
    16621 ttatgcaatt tgattacgcg ggtaaacgtg ttaatatttt ggatacacct ggacatgagg
    16681 atttctcgga agatacatac cgtaccttaa tggctgtgga tgcggctgtc atggttgtag
    16741 attcggctaa aggtattgag gcgcaaacga aaaaactttt tgaagttgtc aaacatcgta
    16801 atattcctgt cttcaccttt attaacaagt tagaccgtga tgggcgtgag cctttagaac
    16861 tcttggaaga attagaagaa gttttaggga ttgcttctta tccgatgaac tggccgattg
    16921 gtatgggacg cgcctttgag ggcttatatg atttacataa taaacgttta gaactctata
    16981 agggagacga gcgttttgca agtattgaag acggtgatca gctgtttgcc aataatccct
    17041 tttatgaaca agtcaaagaa gatattgaac ttcttcaaga agcaggtaat gacttttcag
    17101 aacaagctat tcttgatggt gacctaactc cagtcttttt tggctctgcc cttacgaact
    17161 ttggagttca gacttttctt gatactttct tggagtttgc cccagaacct catggtcaca
    17221 agactacaga aggtaatgtt gttgacccct tagctaaaga tttttcaggt tttgtcttta
    17281 aaattcaagc taacatggac cctaaacacc gtgaccgtat tgcttttgtg cgtattgttt
    17341 ctggtgaatt tgagcgcggt atgggagtta atttgacacg cactggcaaa ggcgctaagc
    17401 tctccaatgt tactcaattt atggcagaat cacgggaaaa tgtgacgaat gctgttgctg
    17461 gggatattat cggggtttat gatacaggaa cttatcaagt tggggatact ttaacagttg
    17521 ggaaaaataa atttgaattt gaacccttac caacttttac cccagaaatc ttcatgaagg
    17581 tttctccgaa aaatgttatg aagcagaaat ccttccacaa aggtattgaa caattagtac
    17641 aagaaggagc aattcagctt tataagaatt atcagacagg cgaatacatg ctgggtgttg
    17701 tgggtcaact gcagtttgaa gtctttaaac atcgtatgga aggtgaatac aacgctgaag
    17761 ttgtgatgac accaatgggt aaaaagactg ttcgctggat ttcagaagat gatttggatc
    17821 aacgcatgtc ctcaagccga aacattttag ctaaggatcg ttttgaccaa ccagttttcc
    17881 tatttgaaaa tgattttgcc cttcgctggt ttgcagacaa atacccagat gtcactttag
    17941 aagagaaaat gtaaccgaaa catgattttc aacagtctaa cgttttggag atcaatttac
    18001 tgagtaactt tttaaaagaa atgagtggct agttatctct tttgcagatt taagattcta
    18061 tcaaaaaacg atatcttcac aactgtaagc atatttatga tttagcggat aatcgtgaaa
    18121 gcgtgttatt gcttatatta gccttatttc ctatcttttt gattctaatt gtgttacact
    18181 agttaggttg ttaatcaaac gacgaaaatt aaaaggttta taaggcagct tcgcactgcc
    18241 tttttagaaa agagaaacaa ttgaaattta cagaatttaa cttatcacaa gacatccaat
    18301 cagctgttgt taccgctggt tttgagaaag catctcctat ccaggaaatg acgattcctc
    18361 tcgcactaga agggaaggat gttattggtc aagcacaaac aggaactggt aaaacagcag
    18421 cgtttggtct accaaccttg aataagattc gtactaacga aaatatcatc caagcattgg
    18481 tcattgcacc aacgcgtgaa ttggctgtac aaagtcagga agaattgttc cgttttggac
    18541 gtgaaaaagg ggttaaggtt cgctctgttt acggtggatc aagtattgaa aaacaaatca
    18601 aagcccttaa atcaggtgcc cacattgtcg tgggaacacc gggtcgcttg ttagatttga
    18661 ttaagcgcaa ggctcttatt ttagatcatg tggaaacctt aatccttgat gaagcagatg
    18721 aaatgcttaa catgggattc ttggaagaca ttgaagctat tattagtcgt gtcccagcag
    18781 accgtcaaac cttgctcttc tccgcaacga tgccggcacc tattaaacaa atcggggtta
    18841 aattcatgaa agaccctgaa catgttcaaa ttaagaacaa agaattaaca aacgtcaatg
    18901 ttgatcaata ctatgttcgt gtgaaagaac aagaaaaatt tgatactatg acccgtctga
    18961 tggatgttaa ccagccagaa ttatccatcg tttttgggcg gactaagcgc cgagttgatg
    19021 aaattacacg tggcttgaaa cttcgtggtt tccgtgccga aggaatccat ggtgatcttg
    19081 accaaaataa acgcttacgt gttatccgtg atttcaaaaa cgaccaaatt gatattcttg
    19141 ttgccactga tgtagcagcg cgtggccttg atatttcagg agttacccac gtttataact
    19201 acgatattac ccaagatcca gaaagttatg ttcaccgtat tggtcgtaca ggtcgtgccg
    19261 gtaaatctgg tgagtctatc acttttgtct caccaaatga gatgggctac ctctcaatga
    19321 ttgagaactt aacgaaaaaa cagatgaaac ctcttcgccc agcaactgct gaagaggcct
    19381 ttcaagccaa gaaaaaagta gccctcaaga aaattgaacg cgactttgcg gatgagacta
    19441 ttcgttcaaa ctttgataaa ttcaaaggtg atgctgtcca attggctgcc gaattcactc
    19501 ctgaagaatt agctttatat attttgagct taacagttca agatccagat agcttaccgg
    19561 aagttgaaat tgcacgtgaa aaaccattac cattcaaata tgtgggtggt ggtcacggca
    19621 ataaaaatgg caaaggtggt cgtggacgtg acaaccgtaa ccgtggtgat cgccgtggca
    19681 gctatcgtgg tgaccgtaac agagatgagc gtgatggtga ccgtcgtcgt caaaaacgtg
    19741 ataagcgtga tggtcacgat ggcagtggca accgcgattt caaacgtaaa tcaaaacgta
    19801 atagtaaaga ctttttcaat aaagagaaaa aatcaagtgc taaaaatact ggttttgtga
    19861 ttcgtcacaa aggtgaataa gcttaaagag agttgatgag agtcagctct ttttaatttt
    19921 ctgaaaaagt tgcttttata atggaatctg ttataatggt ttcagttatt ttgttataat
    19981 ttttaaaaaa ttaggaggag tataagatgt ctgatagcca tcttactgcc tttgacaaag
    20041 cttcaaaagc aggttttatt attgctttag gtattgttta tggagatatt ggaacaagcc
    20101 ccctttatac gatgcagtct ctagttgaaa atcaaggagg ggttaatcag gtttctgaat
    20161 cctttatttt aggatcaatc tctttaatta tttggacact gaccttaatc acaacaatca
    20221 agtacgtttt gattgctcta aaagcggata accaccatga aggtgggatt ttttctttat
    20281 tcaccttggt acgtaaaatg tcaccgtggc tcattattcc ggcgatgatt ggaggtgcaa
    20341 cacttttgtc tgatggggct cttacacctg cggtaacagt tacttcagct attgagggct
    20401 tgaaagccgt tcctggtctg agtcacatct accaaaatca aaccaatgtc attatcacaa
    20461 ctctagtgat tttaatagtc ttgtttggta ttcagcggtt tggaacaggt tttattggta
    20521 aaatttttgg accagttatg tttatctggt ttagttttct aggtgttagt ggttttttta
    20581 atacgttggg gcatctggaa attttcaagg ctatcaatcc ttactatgct ctgcatttgc
    20641 tgtttagtcc tgaaaaccat cgtgggattt ttatcttggg gtccattttt cttgcgacaa
    20701 caggagctga agccctttat tcggatttag gacatgttgg tcgaggaaat atttatgtga
    20761 gctggccctt tgttaagatg tgtattgtgt tgtcttactg tggccaggct gcgtggattt
    20821 tagcgaataa acactcaggt attgaactaa accctttctt tgctagtgtg ccatcacaat
    20881 taagggttta ccttgttagt ttggcaacct tggcagctat tattgcctca caggctctta
    20941 tttcaggctc ctttaccttg gtttcagagg ccatgcgttt gaaaattttc cctttgtttc
    21001 gtgtgactta cccaggggca aatttgggac aattgtatat tcctgtcatt aactggattt
    21061 tatttgcagt gacctcttgt actgttttgg cttttagaac atcagcccac atggaggcag
    21121 cttatggtct tgctattacc atcaccatgt tgatgacaac aatcctctta aagtattact
    21181 taatcaagaa aggaacgaga cccatcttgg ctcatttagc gatggctttc tttgcccttg
    21241 tagaattcat tttcttcttg gcttcagcta tcaaatttat gcacggtggc tatgcggttg
    21301 ttatcttggc acttgcaatt gtctttgtca tgtttatctg gcatgcgggc acacggattg
    21361 ttttcaagta tgtgaaatct cttaatttga atgattacaa ggagcagatt aaacaacttc
    21421 gtgacgacgt ttgttttgac ctctaccaaa caaatgttgt ctacctatcc aatcgtatgc
    21481 aggatcatat gattgaccgg tctattttat actccatttt agacaagcgg ccaaaacgcg
    21541 ctcaagttta ttggtttgta aatgtccagg taactgatga accttataca gctaagtaca
    21601 aggtagatat gatgggaacg gattatatgg ttcgagtcaa cctttatctt ggttttagaa
    21661 tgccacagac tgtgccacgc tatttgcgca cgattgttca ggatttgatg gaaagtggcc
    21721 gtttacccaa acaagaacag gaatatacca tcacacctgg tcgtgatgtt ggtgattttc
    21781 gctttgtttt aatagaagaa cgggtctcca atgcacgtca attgagtaac tttgaacgtt
    21841 ttatcatgca gactaaggca agcattaaac atgttaccgc tagtccaatg cgttggtttg
    21901 ggcttcaata ttccgaagta acccttgaag tggttccctt gattctatca gatgtcttga
    21961 agttaccaat caaagaattg gtgcctgtgg aagacagtga agcataaaac aatcattgag
    22021 atgataagtc tcaatgattt ttcttttctt tttgatgagt agcaatatag gccaatttct
    22081 ggcttcttgt ttttcgtttt ttaaagagtg cttcagcgct catcgcagcc tctttgctat
    22141 caaacacttc gtaataaagt aaagaaacag gtaaccggta gcgagtatat ttagccccct
    22201 ttcctgcgtt atgtgtagct aaacgctttt tcaaatcagt tgtataacca gtgtagaggg
    22261 ttttatcaac acattctaac acatacatat aagctttttt agtggtcatg attaggtttt
    22321 cctttggaag caacaccaaa ataaatctca aaaatatgat cagtgtattc tccgttttcc
    22381 ttgtggacaa ctaaaggagg taaaatagtc atcccttcaa tagaaccgtc tttgattgct
    22441 tcaataagta acatattagc tgatttgcct aatttaggat agacaaattg tacccgttta
    22501 ggggcaagac cattagctct aaggctatct ataatttcca agaatcgatc tggtcgatga
    22561 accattgcca gacgaccatt tgatttaagg gcatgacggg ctacctgaca aatctcttct
    22621 aaattagtgg tcacttcatg acgagccagt aaataatgtt cagagacgtt cttcttagaa
    22681 ctttcgtgac ttttaaagta agggggattg cagagcatca aatcaactcc tgaacgtggc
    22741 acatggttta ggaggttttt taaatcatca caaatcatgg ttacttggtc ttccagttga
    22801 ttgagctgga tagagcgttg tcccatatca gcaagccgtt cttgtaattc gacttcaacg
    22861 atggctgcct tggttctagt gctagcaaat aagccaaccg ccccatttcc tgagcacaaa
    22921 tccacaatta accctttgga aggcatcttg gggaagcggg ataagaggac gctatcaata
    22981 gagtaactaa agacatcctt gttttgaata atgccaacat cacttgaaaa gagttgatca
    23041 atacgttcgc cttcttttaa gattgctttt atcatacctg ttattttaac ataaaatagg
    23101 cttgaggtga atgtttgaag agtgattttg actttcgaaa agtcagcttt catgatacaa
    23161 taagtaagat tattctatta aaggagaagc ctgtgtttta cgcttactta cgcggtttag
    23221 tagtcttttt attatgggtt gtcaatggca atgcccacta tcatcatgaa gaaaagatgt
    23281 tagatgcttc tgagaattat attctggtag caccccatcg aaccttttgg gatccagttt
    23341 acatggcatt tgcagcacgt cctaagcagt ttatttttat ggctaaaaaa gagttgtttg
    23401 caaatcgtct ctttgcttgg tggattaaaa tgtgtggtgc ttttcctatt gatcgtgaca
    23461 aaccgagtcc agatgctatt cgttaccctg ttaatatgct caaaaagagc aatcgttctc
    23521 ttcttatgtt tccaagtgga agtaggcatt cgcaagaggt caaaggaggg gtcgctgtga
    23581 ttgctaaaat ggctaaggtc aagattatgc cagcagccta tcaggggcct atgtcggtta
    23641 agggattact agcgggagaa cgggttgaca tgacttttgg gaatcccatt gacgtctcag
    23701 atattaaacg catgaatgat gaagggattg ctgaggtggc aaaccgtatt caggcagagt
    23761 ttgatcggat ggatgacgag ttggcacctt tccaaccagg caaagcaagg aaccctttaa
    23821 cttatctcta ccgtttacca ttaggattgg ttttggtggt ggtattatta ttaaccatgt
    23881 tattttccta tattgctagt tttgtttgga atccagataa acatcgccat taagaacatg
    23941 agggctaaca tgtgcctgaa ataagaagtg attgagatta gtcttctatt gaaagaagcc
    24001 gctaatgctt aatcactttt ttcatttcta aaaaagatat tcgatgacac ccttaactct
    24061 tttaagcaca aaaatgacaa tactgctata cttttggata tcatttacga ataaaaagat
    24121 gaggtaaaaa aatgttagac gaattattaa ttaaaggaaa atcgtttttg agagagcggt
    24181 attttctgcc atacctaatt agtcttttat taggactttt tctaatacta agcttcagtt
    24241 ttttgttctg gggaaatagg cagagcaagg cagccgttcc tgctttgaga gaaatatcgc
    24301 ctgtgaaaca gcaggttagt gaagaaaaaa aggaaattca agaagatagc agtattttag
    24361 tggatttaaa aggcgccgta caaaaagagg gagtttataa gctaactgct agcagtcgtg
    24421 tgcgagatgt cattgaacta gctggaggcc taacttcaga agctgataaa catgctatta
    24481 attttgcaga aaaactaact gatgagcaag ttgtttatgt acctaaacaa ggagaagaga
    24541 tttctgtgct accaagatca ctagtttctg gtaaaaaaga aactgccagc aaggatcagt
    24601 caaaggttca tattaataag gccagcttag aagaactaca acatatccca ggtattggtg
    24661 ctaaaagagc tcaggatatt attgatatga gagataagtt aggtggtttt aaagcgttag
    24721 aagatctccg tcaggtttcg gggattggcg aaaaaacgct cgagaaatta aaagatgaca
    24781 ttttcttgga ctaagctaat gcccctgtca aagattcaat ttgctttttt aatcttggtt
    24841 ctcttttatc aaatccatag ccctagctgg ttaacgtttc tccttagcct tagtttgatt
    24901 tgcttacttg tcaagcgttt gtctaaaaaa gaatttctcg gtgtctttgc catccttagt
    24961 ttctgtgctt tgtttttgct gtatcagaaa cagcagttgg ttcaaaaact ggaaattcag
    25021 ccagtacaaa taacctctgt agcattagtt cctgatagta ttcggattaa tggtgatcaa
    25081 ttagctgttc ttggacgtca cgggaaacat tcttatcagt tattttaccg tttgaaaagc
    25141 caagcagaag cccaattgtt caagaaagag caccgttggt tagtgatgca cgcaaaagtg
    25201 acattggaaa aagctgagga agttcgaaat tttaaaggct ttaattatca gacttttttg
    25261 gcttatcaag gaatttacag gatagggaag gtagagcaaa tagaacagct tgaagtgatt
    25321 tcacccgagt caatatgtga ctatttgtcc tctttaagac ggcgagccat tgttcattgc
    25381 cagcagcatt ttccaagacc tatgtctcac tacctgacgg gcctcctttt tggttattta
    25441 gataagtcgt ttggtgagat gacagattat tatagtcagt tgggtatcat tcatctcttt
    25501 gctttatcag ggatgcaggt tggcttcttt cttacttgtt ttagaagggt gttgctatta
    25561 ctcgcagttc ctttggaatg gataaaatgg atagagcttc cttttgcttg cttttatgcc
    25621 gcgttgacag gttatagtat ttctgttatt cgaagcctcg tgcagtcgca gttgcgtcat
    25681 ttaggaataa aaggattaga caatctggct tgtacttttt tacttgtctt tttatgggat
    25741 gctcatttct taatgactgt tggtggcgta ttaacgttta gctatgcttt tttgttaaca
    25801 gtggttactg ttgaagaatt atcaggagct aaaagacagt tggtacaagt cttgaccatt
    25861 tccctaggaa tattaccatt tttgctcttt tatttttcca gttttaaccc aatgtcaatg
    25921 gtcttaacag ctctcttgtc ttatctcttt gaccttttta ttttgcccct tctttgtctg
    25981 gttttttgtc tatccccttt ggtgactgtc tcaatatgca accatctttt tattttatta
    26041 gaaaaagtca ttcaatttct cggaaatact ttcaatagtt cccttgtttt tggaagcccg
    26101 accagttggc acttgcttat cttggtgatt agcttcgcta ttttttatga ttatcggcag
    26161 gtgcgacaac gagttatcac ttgcggtttg gttatagcgt tgacgctttt gtctgtcaaa
    26221 tatcctttga ccaatgaagt gacctttatc gacattggcc agggagatag tattttggtg
    26281 agggagtgga cagggaaaaa tctcttaata gatgtaggtg ggcgcccttt cttttcttca
    26341 aaagagcact ggcgacgagg acatcacgta gctaatgctc agaaaacctt aattccttac
    26401 ttaaaaagta gaggtattca cacaattgac caactattag taactcacgc agatactgat
    26461 catatggggg atatcgaagt ggttgccaaa gctattcgga taaaggagat tttgactagt
    26521 caaggcagtt taagccatcc aagctttgtt aggcggctaa ggcgtttaaa atgtcacgtt
    26581 agggttttag cagctggaga ccagttgcct attatgggaa gtgtcttaca ggtactctat
    26641 ccttggcagt taggggacgg gaaaaataac gattctttgg tactttatgg caggctctta
    26701 aatcgaactt ttcttttcac aggtgacttg gaaaaagagg gggaaaacga gatcataaaa
    26761 cgttatcctc aactaagagt agattattta aaagcaggtc accatggatc aaatacctct
    26821 tctagtgcag cttttttaga ccatattcag cctaaagtgg cctttatttc tgctggaaaa
    26881 aataaccgtt atcagcatcc tcacagagaa accttagccc gtttggaaga cagacaaatc
    26941 acttattacc gaacggatac gcaaggagct attcgtttga ctggtcggac aagctggcat
    27001 cttgaaacgg tccgttagtt aaaattccag cctgacgaag aaacaggcag tcgctttcct
    27061 tttaggagaa agatgatata ataaaagcat gattgcgata gaaaagattg aaaaactgag
    27121 taaagaaaat ttgggtctta taacccttgt cacaggagat gacattggtc agtatagcca
    27181 gttgaaatcc cgcttaatgg agcagattgc ttttgataag gatgatttgg cctattctta
    27241 ctttgatatg tctgaggccg cttatcagga tgcagaaatg gatctagtga gcctaccctt
    27301 ctttgctgag cagaaggtgg tcatttttga ccatttgtta gatatcacga ccaataaaaa
    27361 aagtttctta aaagaaaaag acctaaaggc ctttgaagcc tatttagaaa atcccttaga
    27421 gactactcgg ctaattatct ttgctccagg taaattggat agtaagagac ggcttgttaa
    27481 gcttttgaaa cgtgatgccc ttgttttaga agccagccct ctgaaagaag cagagctaag
    27541 aacttatttt caaaaataca gtcatcaact gggtttggga tttgagagtg gcgcttttga
    27601 acaactgctt ttaaaatcaa acgatgattt tagtcaaatc atgaaaaaca tggccttttt
    27661 aaaagcctat aaaaaaacgg gaaatattag cctaactgat attgagcaag ccattcctaa
    27721 aagtttacaa gacaatattt ttgacttaac cagactcgtt ctacgaggaa aaatcgatgc
    27781 agctagagat ttgattcatg atttacgctt atcaggggaa gatgatatta aattaattgc
    27841 tattatgttg ggtcaatttc gcttattttt gcagctgact attcttgcta gagacgtaaa
    27901 aaacgagcaa caactagtga ttagtttatc agatattctt gggcggcggg ttaatcctta
    27961 ccaggtcaag tatgcgttaa aggattctag gaccttatct cttgcctttc taacaggagc
    28021 ggtgaaaacc ttgattgaga cagattacca gataaaaaca ggactttatg agaagagtta
    28081 tctagttgat attgctctct taaaaatcat gactcactct caaaaatagg cattggaccg
    28141 ctttccaaga gataatcaaa ttagttgaaa gctcttattt tttgcgataa gatagacgta
    28201 tcataaagga aaagaggaca ggaaaatggc tattatttta ccagaacttc catacgcgta
    28261 tgatgctctt gaaccacagt ttgatgcgga gacaatgact cttcatcatg ataaacacca
    28321 tgccacttat gttgctaata ccaatgcggc tttagaaaaa cacccagaga tcggagaaaa
    28381 tctggaggaa ctattggcag atgtcactaa gattccagaa gatattcgtc aagccttaat
    28441 taataatggt ggcggacacc taaaccatgc gcttttctgg gaactattat cacctgaaaa
    28501 acaagacgtc actcctgatg ttgcacaagc cattgatgat gcttttgggt catttgacgc
    28561 ctttaaagaa caatttacag cagctgctac tggacgtttt ggttcaggtt gggcatggtt
    28621 agttgttaat aaagaaggac aactcgaaat cacatcaacc gctaaccaag atactccaat
    28681 ttcagaaggc aaaaaaccaa ttctagcgct tgatgtgtgg gagcatgctt actacttgaa
    28741 ttatcgtaat gtacgtccaa attatatcaa agctttcttt gaaatcatta attggaaaaa
    28801 agtatcagaa ctttaccaag ccgctaaata agaaaagggt ttccaatctc aaaaagagat
    28861 tggtttttta agtgcttttg tgaataacag tgtggggaca tcatttttta gaaaagataa
    28921 aaatagtttg tctttttaat gtaattcctt gatttttagc taaatttagc tagaatagaa
    28981 tggataggag attttaggtg ttaagaaaga agaaaactac cattgtaggg attattttag
    29041 gaatgatgat agtgacctta cttgtcggct gtttgactgg taaaaagaaa ggctttcctc
    29101 ctaaagcagg tgagcggcag caaacagctg acttaaaaat gaaaaaagat tagaaaaact
    29161 gttcaaaaac cgttacctga aaaatctaaa gaggctaagc aagctgttat ggatgcctta
    29221 gggctctatt acgatgacaa ccatttgagt ttggtcaata cggtcaaggt gtatttaaag
    29281 gaatttggca ttggtgaatc tcaaattgcc ttttcctaca aagacctcaa ttcaggcagg
    29341 actgctgcca tgaatgatca tcagccaatg attgcaggaa gcacctataa gctgccatta
    29401 aacatgctgg tggtagataa ggcaaattat ccatgacaga gcgttttgac attacagaaa
    29461 ctgattatga atatgatcag gaacatcatg cctatgttgc tcaattcaat ggtgccatgt
    29521 ctattccgga tatgcaagat actcagaaat cacgccagct tatgctctag cagaacgatt
    29581 gggtggcatg aataaggctt accaattatt tgaccgctac gggaaggtat ccggggctat
    29641 tacgaccatt gatcgtaatg gcaataaaat caccaccgct tactatttgc aagttttgga
    29701 ttacttgtgg cagcatcagg ataaatataa ggatatcttg tactacattg gtgaatcttt
    29761 ccctgatttg tattacaaga cttatttgtc tcatgtaaag gtttatcaaa aaccgggtta
    29821 tgtcagagaa gccttaaatg taggtgccat tgtttgcgaa gagtctcctt atttgattgc
    29881 tctttattca tctggtttgg gtggagcaac acaagcatca gaggaagtca atggccttgg
    29941 ttatgtgcag cttgttcagc taacatatgt aattaatgag tggcatagag tcaatcacaa
    30001 catgatctaa tactcagttg acattagtct gatagtagac atacttactg atgacagtca
    30061 ctaaaataag ttgttgctca ttaaaaaagc ttggcctgtt tcttcaggtc aagctttttg
    30121 agattaatgc tgtgtttttg aggtcttatt gtcacctctt gtttcttgat aatggtgaag
    30181 caattttttg aattttttaa cggcagcgcg tgttagctgc ttagatgatt tgccatttct
    30241 gctgtaaatg ggattgtgct tatccctttg ctgttctaaa tcgggaacta gaaaagttgc
    30301 atcaggacta ttaattgctt tttcaataaa agccggatca aaaagcagaa tagggtcaat
    30361 atcaagcaga cggtgcaagt catcgttttg gttgccataa ttgaaagaag aaccattgac
    30421 aatactattt cgcgttaggt tatcaggatc tagtgctact aaaaattgtc cagattctga
    30481 caaaataaac tctgagtgaa aatgaatcaa aatcttatag ttggcttgag gaatattgtc
    30541 tgtatagact gcctgatgat tgccattagc atctaaaata ctagcaacct tattatggta
    30601 tctagaagat tcataaagag cataatcgtc atcttctaga gtagccaaat atttggctaa
    30661 ggcatccgca tcggttttcc ctttattccc ataatgtgag cgaacccact ccatttgctg
    30721 ggttgatatg aggtaacgga gttgatgaat tttccgatta aaacggctat aaggaatgtg
    30781 ttcgagatta acataataag cctgaatcag ggtagataat tggtcccaaa aaggatctgt
    30841 tggcgatagc tttggactta attgtgccaa tacttgctgt gtttgttttg attgtcctgt
    30901 caactcgtct ggcatcttta aatacgtcaa gagcagttgt aaccgttttt gagcttcttg
    30961 aggcgtctgt gccatctctt cttgttgcca aagcttttga aagtcaggtg atcctatcag
    31021 gcgaatgcga ctataaagtt gttcgaaatg ataagagttt cctctaacag cgagttgttc
    31081 aaggtatcct ttttggatgg ctttatagga ccatccgtcc ttatcgagct ttcgaacata
    31141 atcaagcaag tcgtggcgta atttaatagc ttctgaaagc tggagttctc gtaatttagg
    31201 atagttttgg taaaaaggtg ccactaaatc ttgataaagt ttgtgttctt tttcaaaggc
    31261 aatccgctga tagtctttct gccaaaaact gacgcaaaaa gtcagaaaca tcaagaagaa
    31321 tagccatttt ccaagtaatt tcataggttt ttagttgaca aacatggcat cgccaaagct
    31381 aaagaaacga tacttttcgt caaccgcgtg tctgtaagct tcaaggacaa agtcacgccc
    31441 tgcaaaggct gatactagca tcacaagggt tgattttgga agatggaaat tagttgaaaa
    31501 agcatcaact accttgaatt ggtagcctgg tttaataaaa atattggtcc aacctgaatc
    31561 agcttgaatg tccccttgga acttactccc gatggtttcc aacgtacgaa tagaggtggt
    31621 tcctacagct acaacacgac cgccagcttg tttgacgtct cttagggttt gcgctgcttc
    31681 ttctgagagg gaataaaatt ccgaatgcat atcatgctca tcgaggttat ccacggaaac
    31741 aggtctaaaa gtcccaagcc ctacatgtag ggtcaaataa accaaatgta cccctttggc
    31801 ttcgattttt ttgagcaagt ctgttgtgaa gtggagacca gcagttgggg cggccgcaga
    31861 gccattttct ttagcataaa cggtttggta tcgttcagca tcctctaatt tttcgtgaat
    31921 ataaggaggc aatggcattt cgccgaggct ctctaaaact tctaagaaaa tcccatcata
    31981 gctgaattca acaattcgtc caccatgttc taattcgtcg ataatggtgg ctttgagacg
    32041 cccatctcca aaattgactt ggctaccaac cttgagccgt ttggctggct tggctaaaac
    32101 ttcccattga tctccttgtg tatttttaag caaaagcaat tccacatgac catgagtatc
    32161 gggtttttct ccataaagtc tggcaggtaa gacacgggta ttattcatga cgagggcatc
    32221 ccctggattt aattgatcaa tgatatggtc aaaatggcta tcaaccatag ttttttgacg
    32281 gtgatcaata atcaatagtt ttgaactgtc tcttttttcg agtggggttt gggcaatcaa
    32341 ttcttctggt aactcaaaat caaaatcgtt agtattcatt gggactcctt taaagccact
    32401 agtaaatctc ttcctagtaa ctctttcatg taagataaat cttttctatt atatcacttg
    32461 tcgtctaacc cgtcatcttt aatctttcat cagaaagtaa aggataggct tgacaaaaat
    32521 tggtatatac catataataa aaacacgaaa ggtctatacc aattagaaaa ggagaatgac
    32581 atgaaaatta ttcgggtcca agatcagatt gaaggtggga aaatcgcttt taccttattg
    32641 aaagatagct tagctaaggg agctaagacg ttaggattag caacaggaag ttcaccaatt
    32701 agtttttacc aagaaatggt caaaagtcct ttggattttt cggacttaac aagtattaac
    32761 ttggatgaat atgtcggtct ttcagtagag agcgatcaga gttatgatta ttttatgcgt
    32821 caaaaccttt ttaatgcgaa gccttttaaa aagaattact tgcccaatgg tttagcaact
    32881 gatatcgaag ctgaagctaa acgatatgac caaatcattg cagagcatcc gattgatttt
    32941 caagtgcttg ggattgggcg taatgggcac attggtttta acgaacctgg gacctctttt
    33001 gaagaagaaa cgcatgtggt ggatcttcaa gaatcaacca ttgaagctaa tagtcgtttc
    33061 tttacaagta ttgaggatgt gccaaaacaa gctatctcta tgggaattgc ctccatcatg
    33121 aagtccaaaa tgattgttct tcttgccttt ggacaagaaa aagctgatgc gatcaaggga
    33181 atggtttttg gaccaatcac agaagacctc ccagcaagta ttctccaaaa acatgatcat
    33241 gttatcgtca ttgtggatga agctgctgcg tcacaattag actaacctaa ccagtcgtta
    33301 aaccttgtaa gaacaaaaat gaggagatag tcaacctcat ttaagaagaa gtcttgtaac
    33361 ttctatttct tttgcaaggg taaatttatg ttacactact aatatgcgtt tagataaatt
    33421 attagaaggt acaaaagttg gctctagaag tcaagtgaag aaactgatta aggctcaagg
    33481 ggtttgggtt gatcacatgc ctgccagaaa tggtcgacaa aatgttgatc ctggcttgca
    33541 actgattgag gtgactggac agcgagtgac gcatcctaaa cattcttaca ttatcctcaa
    33601 caagccatca ggggtggtct cagctaagaa agatactaac tatttaaccg ttattgatca
    33661 gcttgctgaa gaagataaaa gtccagactt gtatcctgtt ggcagattgg atagagatac
    33721 cgaagggttg gttttactca ctgataatgg tcccctaggg tttcggatgt tgcaccctag
    33781 tcatcatgtt tctaaaacgt atcttgtaac cgttaatggc ttgttagcag aagatgcctc
    33841 agattttttt gcagctggta tttgtttccc aacaggtgaa caatgccaac cagctcaatt
    33901 gactattctt aaagccgata cagaccagtc acaggctagt ttgaccattt cagaaggaaa
    33961 atttcaccaa gtgaaaaaaa tgtttttgac ctatggtttg aaagtgacct ctctgaaacg
    34021 gacgcacttt gcaggactgg aactcggtca tttagccagc ggagaatatc gttatctaac
    34081 agcgtcagaa aggcaactca ttaaaacgta tctggactga gcaaaacatg ctttcaaaaa
    34141 gaagctattc ttgcttaatc aataaagtgt ccattgacta ttatagtcat gatgagtccg
    34201 acttttgcta tgtttagtca tcttgttgtt acaaaatcag ataagcaaaa agattcaatt
    34261 cccactatct ccttaacctg aagcgttata aaaacccttg tgttaaactc tcataaaatt
    34321 ggaaatggga gtgttttttg atggctaaaa aaaactaaag ctacttaaag tttggtactt
    34381 agttttcgaa taataaggtg gaagatctaa taggaggtga caaaaatatt aaccgcttta
    34441 gatggtaaga atcagctcat ttcgctagta actcagccta tttcaacgaa accgcctttt
    34501 cgttgcccag cttgcaaatc tcctgttcgc ttgcgtcagg ggacaattag acgacctcat
    34561 tttgcccatg tacaactagc tcattgtcaa ttccaagcag aaaatgaatc tgaggaacat
    34621 ttgacgttga aggcaaaact ttacaccagt ttagtccgaa cagaagctgt ctgtattgaa
    34681 aaatatcttc ctgagctgca acagatagca gacctttggg tgaatgataa gttagcctta
    34741 gaaattcagt gcagtccctt gccagttgag cgtctaaaga aacgcaccaa agcctatcaa
    34801 gaaaaggggt atccggtacg atggttactg ggaagaaaat tgtggcttaa cactcactta
    34861 actgctttgc aaaaacagtt tctttacttt tcatctagtt tgggctttca tttgtgggag
    34921 ctggatgcag ctgcaaatct gctacgtctc aaatatttaa tccatgaaga cttatttggt
    34981 aaggtaagtt acctaaccaa aaccatttct ttagaccaca atattatgga aatgtttcga
    35041 ttaccctatc agcaagaaat cctttattct tatcagaaaa aaatgactgt gaacctatct
    35101 aaaagaatac aaagagctct tttagctaga cacccgaaat ggctacgacg acaagaaaag
    35161 gcttacttat caggctataa tttacttatg ttaacaactg atgcttttta tcctcaatgg
    35221 agaccagttc aatcttccag cggtttttgt caaattaaag gaaatcttcg cccttattat
    35281 gaaagtttta a
//
LOCUS       DAUCXI010000019        31059 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.019, whole genome shotgun sequence.
ACCESSION   DAUCXI010000019 DAUCXI010000000
VERSION     DAUCXI010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31059
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.019"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..140
                     /locus_tag="VGY43_000941"
     CDS             <1..140
                     /locus_tag="VGY43_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ4302137.1"
                     /translation="MAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQAIQKKQV
                     S"
     gene            189..869
                     /gene="radC"
                     /locus_tag="VGY43_000942"
     CDS             189..869
                     /gene="radC"
                     /locus_tag="VGY43_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEQ4302138.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(871..1566)
                     /locus_tag="VGY43_000943"
     CDS             complement(871..1566)
                     /locus_tag="VGY43_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEQ4302139.1"
                     /translation="MTKPIIGITANQRLNMALDNLPWSYAPTGFVQAVTQSGGLPLLL
                     PIGDEAAAKTYVSMVDKIILIGGQNVDPKYYQEGKAAFDDDFSPERDTFELAIIKEAI
                     TLKKPILGICRGTQLMNVALGGNLNQHIDSHWQEAPSDFLSHEMIIEPDSILYPIYGH
                     KTLINSFHRQSLKTVAKDLKVIARDPRDGTIEAVISTNDAIPFLGVQWHPELLQGVRD
                     EDLQLFRLFVNDF"
     gene            complement(1576..2220)
                     /locus_tag="VGY43_000944"
     CDS             complement(1576..2220)
                     /locus_tag="VGY43_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEQ4302140.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(2472..2819)
                     /locus_tag="VGY43_000945"
     CDS             complement(2472..2819)
                     /locus_tag="VGY43_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEQ4302141.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLETIPNSGDGFPLKITINKELTGFKLAITDQSGLRLVNIFKTKDNQILQDKFYFLMD
                     SLVEREIFSKTVV"
     gene            complement(2809..3936)
                     /locus_tag="VGY43_000946"
     CDS             complement(2809..3936)
                     /locus_tag="VGY43_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEQ4302142.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKGI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            complement(3933..4913)
                     /locus_tag="VGY43_000947"
     CDS             complement(3933..4913)
                     /locus_tag="VGY43_000947"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ4302143.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAADVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            complement(5053..5631)
                     /locus_tag="VGY43_000948"
     CDS             complement(5053..5631)
                     /locus_tag="VGY43_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEQ4302144.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLFQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFVNSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHITFKYAKSKVARCINTLKKFNDK"
     gene            5719..6390
                     /locus_tag="VGY43_000949"
     CDS             5719..6390
                     /locus_tag="VGY43_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEQ4302145.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKEKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            6365..7201
                     /locus_tag="VGY43_000950"
     CDS             6365..7201
                     /locus_tag="VGY43_000950"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEQ4302146.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEI
                     DS"
     gene            7198..8103
                     /locus_tag="VGY43_000951"
     CDS             7198..8103
                     /locus_tag="VGY43_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEQ4302147.1"
                     /translation="MRFEFVADKRIKVKTLLKSHDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGTLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSYAIHLTDDFDSVIIGLQKKDRGY"
     gene            8107..9102
                     /gene="pta"
                     /locus_tag="VGY43_000952"
     CDS             8107..9102
                     /gene="pta"
                     /locus_tag="VGY43_000952"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEQ4302148.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKEAFVDIRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIAKGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFIFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            9229..9984
                     /locus_tag="VGY43_000953"
     CDS             9229..9984
                     /locus_tag="VGY43_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEQ4302149.1"
                     /translation="MGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKALET
                     SFGSDNFYPLQMDVTDTKVIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENW
                     MTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTISYPGANIYGASKAFVKQF
                     SLNLRADLAGSHIRVTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIAST
                     VSWVIHQPPHVNVNRIELMPVSQSYGPQPVTRD"
     gene            complement(10177..10866)
                     /locus_tag="VGY43_000954"
     CDS             complement(10177..10866)
                     /locus_tag="VGY43_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEQ4302150.1"
                     /translation="MKNAISILALLTPENQLEDTFIRELSHHFSHLFEVTILTSKANI
                     ESNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTRF
                     YQKFDRHFLEYLPLQARLSDAKGNILVDNHAFNGSFLPTTDNEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLDTVQDIKPLLSQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            11283..12011
                     /locus_tag="VGY43_000955"
     CDS             11283..12011
                     /locus_tag="VGY43_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302151.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQKELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPDM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVVNLFGGDEHA"
     gene            12004..13530
                     /locus_tag="VGY43_000956"
     CDS             12004..13530
                     /locus_tag="VGY43_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEQ4302152.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKVARDYLLKTGLIQK
                     "
     gene            13808..14791
                     /gene="guaC"
                     /locus_tag="VGY43_000957"
     CDS             13808..14791
                     /gene="guaC"
                     /locus_tag="VGY43_000957"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEQ4302153.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKAYEY
                     EFVTSLKEDTPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLSALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTVEVNGETFKEYYGSASAYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     regulatory      14914..15009
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            15096..15677
                     /locus_tag="VGY43_000958"
     CDS             15096..15677
                     /locus_tag="VGY43_000958"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEQ4302154.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     gene            15677..16960
                     /locus_tag="VGY43_000959"
     CDS             15677..16960
                     /locus_tag="VGY43_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEQ4302155.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSSAM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVAGTLVSAMMGLVDTTPVVEASWIH
                     VPTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFTS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(17024..17962)
                     /locus_tag="VGY43_000960"
     CDS             complement(17024..17962)
                     /locus_tag="VGY43_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEQ4302156.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPVSVHSDLFNLIQIGKAYSLSTPSNLNIAIGPLVQAWRIGFE
                     DARVPSHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVLVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTAKGKQYHHILDRQTGYPIETDMLSLTVMAPSSFYCDIWATRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(18015..18200)
                     /locus_tag="VGY43_000961"
     CDS             complement(18015..18200)
                     /locus_tag="VGY43_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEQ4302157.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            18338..18907
                     /locus_tag="VGY43_000962"
     CDS             18338..18907
                     /locus_tag="VGY43_000962"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEQ4302158.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPEI"
     gene            18942..20021
                     /gene="prfA"
                     /locus_tag="VGY43_000963"
     CDS             18942..20021
                     /gene="prfA"
                     /locus_tag="VGY43_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEQ4302159.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            20021..20860
                     /gene="prmC"
                     /locus_tag="VGY43_000964"
     CDS             20021..20860
                     /gene="prmC"
                     /locus_tag="VGY43_000964"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEQ4302160.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLAYVFREIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERSNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISGTFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLAKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRVVTDIFGKERMVVVDYG
                     VSS"
     gene            20844..21434
                     /locus_tag="VGY43_000965"
     CDS             20844..21434
                     /locus_tag="VGY43_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEQ4302161.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPNHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAITKEELLANVPELRF"
     gene            21452..21904
                     /locus_tag="VGY43_000966"
     CDS             21452..21904
                     /locus_tag="VGY43_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ4302162.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALESQA
                     RQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            21894..23150
                     /locus_tag="VGY43_000967"
     CDS             21894..23150
                     /locus_tag="VGY43_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEQ4302163.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     PYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIARLIIKALVN
                     HDQETILEEVRQEVRQLTDAFPLYKK"
     gene            23157..24134
                     /locus_tag="VGY43_000968"
     CDS             23157..24134
                     /locus_tag="VGY43_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEQ4302164.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDVLSPEKLADQLFDDNLTARLTFVDQVKEVIPEPIKISDIDHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            24135..24734
                     /locus_tag="VGY43_000969"
     CDS             24135..24734
                     /locus_tag="VGY43_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEQ4302165.1"
                     /translation="MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAEN
                     DTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLAL
                     AEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPSLGNTSGQTYF
                     YYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF"
     gene            24744..26468
                     /locus_tag="VGY43_000970"
     CDS             24744..26468
                     /locus_tag="VGY43_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302166.1"
                     /translation="MKRLRPYLKGYLKESILGPLFKLLEALFELLVPLLIANMIDISI
                     SQHNSQGILRVVLTLFGLATIGLLLSVTAQYFSSKAAVGFTRQMTDDLFKKIMFLSKE
                     DQDHLGYASLLSRLTSDSFQIQTGINQFLRLFLRAPIIVCGATVMAYWISPSLTLWFV
                     MMVIVLLTLVFVMSHLLGPLYLLIRRETDHLVRLTSQQLQGIRVIKAFNQTQKELQAF
                     KQQNMLLSRHQYQAATLANVLNPMTFLVVNLTLLILIWQGSWQVAHRSLSQGMLVALI
                     NYLLQILAELLKMTMLMGTINQSVTAAKRINQVFVLADEAPLPSLKDGPISTHLLTIR
                     HLTFTYPGAAEPSLYDIQLSADQGEWIGIIGGTGAGKTTLIDLICQTYSPYSGEISLN
                     WQGEVPKTLTEWRNVIALVPQKAQLFKGTIRSNLLLGQSMPISDEELWRALELAQAKE
                     FVAALPEQLEAPVEAFGRHFSGGQRQRLAIARALLKPKPILILDDASSALDNETRGRL
                     FKALKEELSDVLVILVTQSIKNLQFADKILVLEQGHQLDFASHDQLKVSNALYQEMLA
                     LYVKGEQK"
     gene            26465..28180
                     /locus_tag="VGY43_000971"
     CDS             26465..28180
                     /locus_tag="VGY43_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302167.1"
                     /translation="MIKTDHHLLKRMLHDLLKKPLPVCILVIASFVQVGLSVYLPVLI
                     GKAVDMSLSVNSWQTLKWLLGQMLVVIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTILCTIIAMAQID
                     WFMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNA
                     QEQSICDYHVLNKTYCEASQKVIFYASTVNPATRFINSVIYALLAGLGAVRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSVLAEIQSSLACAQRLYDLLDIEIKEEEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVPAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRGEVVAAA
                     KAAHVHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSID
                     IRTEAVIQEALKERTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNGCYAR
                     LQKIE"
     gene            28421..29791
                     /locus_tag="VGY43_000972"
     CDS             28421..29791
                     /locus_tag="VGY43_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEQ4302168.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDVSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(29950..30933)
                     /locus_tag="VGY43_000973"
     CDS             complement(29950..30933)
                     /locus_tag="VGY43_000973"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEQ4302169.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
BASE COUNT         9647 a         5378 c         6343 g         9691 t
ORIGIN      
        1 taatggcaat tacaataggc gcttctttaa agggaatagt tggtatgatt attgcagttc
       61 ctttagcagc gacactttat caagtgatta aagataatat tcaaaaaaga caagctattc
      121 aaaaaaaaca agtttcctaa aaggaacttg tttttttgtc gaataaaaag atggaggtaa
      181 tatgataaat gtattctata aaatgtgatg ataataaagc catgccaaga gaacgtttga
      241 tgcgactagg agcagagtct ctaagtaatc aagaattatt agcaatttta ttacgaacag
      301 gtaataaaga aaagcatgtc ttagagctgt catcctatct tttatcgcat ttagacagtc
      361 tggcagattt taaaaagatg tctttgcaag aattacaaca tttggcaggt ataggaaaag
      421 ttaaagcgat tgaaattaaa gctatgattg agttggtttc ccgaatttta gcgacagata
      481 agacattaac tgatagcgta ttaaccagtg ttcaggtcgc tgaaaaaatg atggcagctt
      541 taggagataa aaaacaagag catttagtcg tattgtattt agataatcaa aatcgtatta
      601 ttgaagaaaa aactattttt attgggactg tccgacgttc acttgcagaa ccaagagaaa
      661 ttttatacta tgcctgtaaa aatatggcga ctagtctcat tgttattcat aatcatcctt
      721 caggaaatat tgaacctagt tctaacgatt attgctttac tgaaaaaata aaacgatcat
      781 gtgaagattt aggcattatc tgtctagatc acattatcgt tagctataaa gattattata
      841 gttttcgaga aaaatcaacc cttttttaag tcagaagtca ttgacgaata agcggaacaa
      901 ttgtagatct tcatctcgaa caccttggag aagttcagga tgccactgaa cacctaaaaa
      961 aggaatggca tcgttggttg atatgactgc ttcgatggta ccatcacgtg gatctctagc
     1021 gattactttt aaatccttag caacagtttt taaactttgg cgatgaaaag aattaattaa
     1081 tgtcttatga ccataaatag gatataagat agagtctggc tcaataatca tttcgtgtga
     1141 taagaaatca gaaggcgctt cttgccaatg tgagtcaatg tgttggttaa gatttcctcc
     1201 taaggcaaca ttcattaact gtgtaccacg acaaatccct aagattggtt tttttaatgt
     1261 tatagcctcc ttgatgatag ctagctcaaa tgtgtctcgc tctggtgaaa aatcatcatc
     1321 aaaagcagcc ttcccttctt gataatattt tgggtcaacg ttttgcccac caattaaaat
     1381 gattttatca accatagata cataagtttt agcggcggct tcatcaccaa tgggtaaaag
     1441 aagcggcagc cccccagatt gagtgactgc ctgtacaaat ccagtaggtg catatgacca
     1501 tgggagatta tccaaagcca tatttagtct ttgatttgca gttattccaa taatcggttt
     1561 ggtcattata cctccttaat ctagatgatt ttgattcata aaatagagta gtgtctggag
     1621 ctcactggtc aaatcgacag attgaacaat aactccttta ggaacttgta ggtgaacagg
     1681 agcaaaactc aagattcctt tgattcctgc ttcaataagt tgatcagtaa cttcttgagc
     1741 atgaatgctg ggaaccgtta agatagccgt ttcaatgtca gtgttcgcaa tccgttcttt
     1801 gacagatgag ataccatgga ctggaatatt atcagctgtt ttagtaccaa caagagcgtt
     1861 atcatcggta tcaaaaccca tggcaatttg catcttatta cgatcatgga agcggtaatg
     1921 taatagagca cgccctatat taccgcatcc aactaagata acgtttgttg tagagtgatc
     1981 attaagcaag tcagcaaaaa aattcatcaa tttggtaaca tcatagccaa acccacgacg
     2041 ccccaattct ccaaaataag aaaagtcacg gcgtacagta gcagagtcaa ttcccattgc
     2101 atctgcaatt tgtttagaac tggctttttc aacttggtca gcatggaatc gtttaaaaat
     2161 acggtaataa agtgataagc gctttgcagt cgcttttgga atagatttgt caataaccac
     2221 tattttactc cttgtagatt tctcgttaaa tatgtctgtc tttattgtaa caaaaagatt
     2281 gtgaaaaatg caacattttg attgtttttg tatgagttaa aaaagctaaa attagtttta
     2341 gcactatata atagtattca ttaggaaagt aagttatgac agtcaaaatg aacaacatga
     2401 attaatagca atagaagcga aatcatttat tgacattgtg atatgactaa aaaaacaaaa
     2461 tttaaagttg attagacgac tgttttgcta aaaatttcac gttctacaag gctgtccatc
     2521 aagaaataaa atttatcttg aaggatttga ttatcttttg ttttaaaaat attaactaat
     2581 ctaagaccag attgatcggt gatagctaat ttaaaacctg tgagttcttt attaatagtg
     2641 atttttaaag ggaaaccatc ccctgaatta ggtattgttt cgagtaaacg tattaattgg
     2701 tagtgcccta ctttagtttg actaaatgta gtatctctta gggtatattt tttaatgttt
     2761 ggactgattg tataaaggta tttacagtct ttaagcttaa tttctttttc aaaagccatc
     2821 tgttcctcct aaaatatttt ttaatgtttg agctaattga ttaacatctt caatgctatt
     2881 ttgatctgaa aaactgatac gaattgattc ttttaaacga gaagagtcat ccccatagta
     2941 cgcagctaaa acatgacttg gattaacagc tccagcagta caagcagaac cagttgatac
     3001 tgcaatgcct gctaagtcaa gttgtgttag taaaatagta ttttggtagc ctaaaaatcc
     3061 aatattgaga acatgaggaa gataatgagt accttgatta atatagtagg gtagtccttc
     3121 taggaggcta atcaagtgat gacgtaaact gataatgtga tcagttgatt ggtcaagaca
     3181 agtcatagca tcagtcaaag cttgtgccat accaataata cctaacatat tttcagtact
     3241 tgcgcgtcgc tttccttctt gatcaccccc gtgaagaaga gggtcgattg gttgtccgtt
     3301 actgtataaa aagccgcatc ctttaggacc atgaaatttg tgagcagaag cagataaaaa
     3361 gtcaatccca agttcgctag gaataatctt gagtttgcca acagcttgaa cggcatcaac
     3421 atgaaaagca gcttgatggt ctttgagcag attcccaatg cccttaatag gtaacaggtc
     3481 acctgtttcg ttattggcat acattatgct taccaaaatg gtgtcatctc tcaaggcttg
     3541 ttttaagtca gataaattta tttgtccatt ttgacaaggc aaataagtga cctcaaaacc
     3601 aaatcgctct tcgagatagg ccatggtatg aagaacagag tggtgctcaa tagtagttgt
     3661 gatgagatgt ttgccctttg cttgatgagc taaagcatag ccttttatgg ccatattatt
     3721 gctttcagtt ccaccggacg ttactataat ttgctgttca cttgccccca agtttctagc
     3781 gatagcttgt cggcattcac gaaggatttt attggctcgg cgcccgtaga aatgaatact
     3841 agaggggtta ccaaagttat cttgcatagc tgctgtcatc gccctaatca cattaggact
     3901 aagtggtgtg gtggcggcgt tatcaaagta agtcatgcgt tatttttgcc tttaggttga
     3961 taagaaaaaa gtggacttaa gggtcttctt tcatggatac gaataatagc ttctgcgatt
     4021 aaatcactgg cgctaagata agtaacgttt tctggcacac gatttttagt tttaacagaa
     4081 tctgtaacga taatttcttt gattggagct gtttctaata catcagcagc tccaccagca
     4141 aataagccat ggctagcgac cgcgtaagta tcagtagcgc ctgagcgttc aagaatttta
     4201 gcagcttctg caaaggtttt cccagtattt aaaatatcat caattaaaat ggctttttta
     4261 ccagaaacat caccaataat ataaccttgt tcacgttcag aatcatcttg tgcatagtcg
     4321 ataatagcaa tcggggaatc aagatattca gccaagcttc tagcacgttt aattccagaa
     4381 tttttagggc taacgacaac aacatcagaa cctgataagc ctaatttact gtaacgttct
     4441 gcaaaaagag ggactgtaaa gaggttatcc actggaatat caaaaaaacc ttgtacctga
     4501 acagcatgta agtcaagcgt cactacacga tcaataccag ctttagtcag catattagct
     4561 actagtttag cagtaatcgg ttcgcggggc ttagcgacac ggtcttgacg agagtaacca
     4621 aagtatggca atacaatatt gacggtatta gcacttgcac gtttacaagc atcaatcatg
     4681 atgagtaatt cccaaagatt atcattgaca ggaaaactag tggattgaat aatatagata
     4741 tcatctccac gaactgtttc ttcaatattg atcataattt ctccatcgga aaattgacgt
     4801 gaagacattt ttccaagagg gattccagca gctttagcaa ttttttcagc aattggaaga
     4861 tttgatgtga gtgagaacag tttgatttgc ttgtcagcat atcgttcagt catgatagat
     4921 ttagctcctt aacttcaata aaattgggta aactgtttta ttaatgagtc acattaccca
     4981 aaagtgttta attgacatcc ctattttaac agaaaaacag aaaaatttca gtttttctgt
     5041 cgcttttagc cattatttat cgttgaactt ttttaaggta ttaatacacc gagctacttt
     5101 gcttttagca tatttgaaag taatgtgatg ttcagataaa aaagaatcaa aatcaatctt
     5161 tccttgaaga gcgtcactta cttctaattc taattcatag tctttggtat tggcatatag
     5221 gttatagtct aaggccaatt tacctatcgg tatcactgtc tcgcgacgaa cggtagttaa
     5281 attgccaaaa gttaccagtg cagatggttt gatacctttt gaaataataa tatcaagagc
     5341 agttgattca ggaagattcc catgtttaat catatctttt gcttgttcaa gaaaaagagg
     5401 gacattgtac tcacgattcc ccactttttc tggcactttt aaggttaatt cggcgctatt
     5461 tacaaatgtt cgaatacgta atgacatttt gttagctttt aaatcaaatg cttttgtatc
     5521 aatatagtaa ttagtttgtg taacaggcgt cacatgtttc atttgaaata aaagacggtt
     5581 atactcattt tttgtaagta gagttttata ttcgatttct aggttagtca tgggaaattc
     5641 cttttaattt gtgctataat aaattgttat ttcaatttta tattattatc ctggctttga
     5701 caagaaagga gacaatagat gaccttagat tgggaagaat ttttagatcc ttatatccaa
     5761 acagttggtg aattaaaaat aaaactacgg ggtattcgca agcaatatcg taagcaaaat
     5821 cgttattctc cgattgaatt tgttacggga cgtgttaagt caattgaaag tattaaagaa
     5881 aaaatgattt tacgtggtgt tattgaagaa aatatagcac aagatattca agatattgct
     5941 ggactacgta ttatggttca gtttgttgat gatgtggaag aagtcttagc tctattgcgt
     6001 caacgacaag acatgacaat tgtttatgaa cgagattata ttcgcaatat gaagtccagt
     6061 ggctacaggt cttatcatgt ggtggttgag taccctgttg ataccattga gggtcaaaaa
     6121 aaggtcttag cggagattca gattcgtact ttggcaatga acttttgggc gaccattgag
     6181 cattctttaa attataaata tggtggagac ttcccagaag aaattaaaaa gcgtcttgaa
     6241 gtgactgcta aaattgcctt agaattagac gaagaaatgc gtaagattcg agaagatatt
     6301 cgggaggctc aattattgtt tgaccccgtg acacgaaatt taagtgatgg tgtaggaaat
     6361 agtgatgaca cagatgaatt atacaggtaa ggtaaagcga gttgctatta ttgcaaatgg
     6421 taagtaccaa agtaaacgcg ttgcctccaa acttttctcc gtatttaaag atgatcctga
     6481 tttctatctt tcaaagaaaa atccggatat tgtgatttct attggcggag atgggatgct
     6541 cttatctgct tttcacatgt atgaaaaaga attagataag gtacgttttg taggaatcca
     6601 caccggtcat cttggctttt ataccgatta tagggatttt gaagttgata aattgattga
     6661 taatttaaga aaagacaagg gagaacaaat ctcttatcct attttaaaag ttgctattac
     6721 tttagatgat ggtcgtgtgg ttaaagcgcg tgctttgaat gaagcgacgg ttaagcgtat
     6781 tgaaaaaacg atggtagcag atgttattat taaccatgtc aaatttgaaa gcttccgagg
     6841 tgatgggatt tcagtatcga ccccgacagg gagcacagcc tacaataaat ctttaggtgg
     6901 tgctgtcttg catccgacga ttgaagcgct gcaattgacg gaaatttcca gtcttaataa
     6961 ccgtgtcttt agaaccttgg gctcatcaat cattattccc aaaaaagata agattgagtt
     7021 agtgccaaaa cgattaggaa tttataccat ttccattgat aataaaacct atcagttaaa
     7081 aaatgtgacg aaggtggagt attttatcga cgatgagaaa attcattttg tttcctctcc
     7141 gagtcatacg agcttttggg aaagggtcaa ggatgccttt attggagaga ttgactcatg
     7201 agatttgaat ttgtagcaga taaacgaata aaagtaaaaa cccttttaaa aagtcatgat
     7261 gtctctaaag gactattggc taaaatcaaa tataagggcg gtaatatatt agtgaatggt
     7321 attgaacaaa atgccattta tttattgcaa gtgggagatg ttgtcaccat tgacattcca
     7381 aacgaagagc cctttgaaaa gcttgaagcc atcccttttg atttggatat tgttcacgag
     7441 gatgatcatt ttttggtgat taataaaccc attggctttg ccagtattcc aagtgccatc
     7501 cactccaata ccattgctaa ctttatcaag gcatattatg tggacaatca ttacctagac
     7561 caacaagtgc atatcgtgac tcgtttagac agagatacga gtggcttgat gttatttgct
     7621 aagcacggtt atgctcatgc aaggttggac aagcaactcc aaactcgctc aatagagaaa
     7681 cgttattttg ctctggtttc tggaaatggg acgttgccag atgaaggaga tattattgct
     7741 ccaattgggc gttcaaaaga tagtattatt accagggcag ttgaccctat gggcaaatat
     7801 gccaagacta gctataaggt tgtggcgcgc tattcagaaa atgtgcattt agtggatatc
     7861 aaattgcata caggacgtac ccatcaaatc agagttcatt ttgcccatat tggttttcca
     7921 cttttagggg atgaccttta cggaggtcgt ttggacttag gaataacaag gcaagcttta
     7981 cattgtcatt atttgaattt caaagatcca tttacagaaa gtgattgtag ctatgcaata
     8041 cacttgacag atgactttga tagcgttatc ataggtttac agaaaaaaga tagaggttat
     8101 taaagaatga gtattcgtag tttattcggt ggtttaagag aaaaaattct tggtaaaaac
     8161 atgaagattg ttttcccaga aggtaatgat gagcgcgtcg tccgtgcagc tgctcgtttg
     8221 aaatttgaag gactcttaga accgattatc cttggacagt cagaagaggt acgcaacctt
     8281 ttgacaaaat taggtttcgc tgatcaagac tatactatca ttaatccaaa tgaatatgcg
     8341 gattttgaca aaatgaaaga agcttttgtt gacatccgta aaggaaaagc aacgcttgaa
     8401 gatgctgata aaatgcttcg tgatgtgaat tactttggtg ttatgttggt taaaatggga
     8461 ttagcagatg gaatggtatc tggtgctatt cattcaacag ctgatactgt tcgtccagcc
     8521 cttcaaatca ttaaaaccaa accaggtatt tcaagaactt caggtgtttt cttgatgaat
     8581 cgcgaaaata cgagtgagcg ttacgtgttt gctgattgtg ctatcaatat tgacccaaca
     8641 gcacaagaat tggcagaaat cgctgttaac acagctgaaa cagctaaaat ctttgatatt
     8701 gatcctaaaa ttgctatgtt aagcttctca acaaaaggtt ctggtaaagc gcctcaagtt
     8761 gataaggtaa gagaagcaac agaaattgct aaagggttga atcctgattt ggcacttgat
     8821 ggtgagttgc aatttgatgc agcctttgtt cctgaaacag cagctatcaa agcaccagat
     8881 tcagcagttg ctggtcaagc taatactttt attttccctg acttacaatc tggaaatatt
     8941 ggttacaaaa ttgcacaacg tttaggaatg tttgatgcta ttggaccaat cttacaagga
     9001 ttgaacaaac ctgttaatga tttatctcgt ggctcaagcg ctgaagatat ttacaaatta
     9061 gctattatta cagcagcaca agctattgaa agccaagggt aacttaagac cccttgatat
     9121 aggatcctaa ccgctaagtg atgtgttaga agttgtccta agactaattg acattattaa
     9181 aaacgagttg gccagaccat ctcgtttttt ttgaaggtga ggaaatgtat gggaaatatt
     9241 gccttagtaa caggggcttc agccggtttt ggcagagcca ttgtcgaaca cttaattgca
     9301 gatgggataa aggttattgg tgcttctcgt cgtcttgaga aactcaaggc cttagaaacg
     9361 agctttgggt cggacaactt ttaccctttg cagatggatg tcacagatac caaagtgatt
     9421 gatgatgctt tgacaagtct accaaatcag tggcaagata ttactatttt agtgaataat
     9481 gcaggcttgg cattgggact tgataaggct tatgaagccg attttgagaa ttggatgacg
     9541 atgattaaca ctaatattgt tgggttgatt tatctcacac gtcaattatt accacatatg
     9601 gtctccaaag atgatggtat tattattaat ttagggtcaa ccgcagggac aatttcctat
     9661 ccgggagcta atatttatgg ggctagcaag gcttttgtta agcagttctc actcaattta
     9721 cgagctgatt tagcaggtag ccatatacgt gtgaccaata ttgaacccgg tctatgtgaa
     9781 gggacagaat tttcaaaggt tcgctttaat ggtgatgagg cacgggtgaa ggccatttat
     9841 caaggagcac atgccattca acctcaagat attgcgtcga ctgtatcatg ggtgattcat
     9901 cagccccctc atgttaatgt taatcgtatt gagctgatgc cagtgtcgca aagttatgga
     9961 ccgcaaccag ttactcgtga ctagcaaggg atgagtccat aagaataata atctttagaa
    10021 aaatggttta ctggaatgga ttattcttta taagtgagac ttaccgattt agtcatcaaa
    10081 aaaagcagtc aagaagaagg ttttgatgtt tccaagtgtt cttgattgct tcttgtgcgt
    10141 tgatgattta ggctggactc cctattaaaa tcaagtttag tgatctaaaa tggaaggacc
    10201 tgatgtcaca tcggaccagc caacaatggc ttgtccagtt tcttctaaat actggcttaa
    10261 taacggttta atgtcttgga cggtatccaa aactcccacc agctgacctt gaggattttt
    10321 aagagcttga taatgctgca tgtaaatatg atccaatgaa cccgaaggaa gtaggaaggt
    10381 tttacaaggg ttatctgata aacgcaattc agcaagaatc caatcttcta tttcgttatc
    10441 agtagttggc aaaaaacttc cattaaaagc atgattatcg actagaatgt tcccctttgc
    10501 gtcagataac cttgcttgca aaggaaggta ttctaaaaaa tgtctatcaa atttttggta
    10561 aaatctagtg aggtattggc ttaacgataa gactgctgtt gcttgatcaa agacactttc
    10621 tgtcactaaa aatccctgac catgttgaga ggttttgaaa tagagtgtag gcaagtcaat
    10681 gtcatgctca tggaaactga aaattccttg gaaagtcgac aattgatttg actcaatgtt
    10741 ggctttgcta gtgagaatag tcacctcaaa aaggtgtgag aagtggtggg aaagctctct
    10801 aataaacgta tcttcaagtt ggttttcagg tgttaagagc gctaaaatgg aaatggcatt
    10861 tttcataatt gtatgatagc cgtattttct agaaaagaca actaatctgc ttatctatca
    10921 taggcaagtc taggattttt gataaggtaa ttttggagag gtaggctgac ccagtgacct
    10981 gtttttctat aagggggtaa tagtctcatt atttgactta tagtgggaaa ctttttataa
    11041 tggtcaacaa caaacgacaa gaaaataatg agagaaaatg tttttgagaa ttggtagttt
    11101 ttaccttact gaggatacct aagagtccct ttaattagta gatgcgtttg tctaaaaatg
    11161 gtagggcatg cagtgattcc ttgtagttac tcagaacgtt ttgagaaaaa atgacagaga
    11221 gacaggttga atgaactcat cagcttttat gctgttactt taaccaatga attggagaga
    11281 taatgatacg ttttaataat gtttctaaaa cttttggtca gacaaaggtt ttgcaagagc
    11341 agacctttca aattaatgac cgtgaatttt ttgtgctggt tggccccagc ggatcgggga
    11401 aaaccacact tttaaaaatg attaactgcc ttattgaacc aagctctgga gatattttac
    11461 tgaataacgt cccacagaaa gagttagatt tacgtgagat gaggctatct attggatacg
    11521 tgttgcagca aattgctctt ttccccaatc tcacagtagc tgaaaatatt gcgattatcc
    11581 ctgatatgaa gcaatggtca gctgaagaaa ttagacaaaa aactgaagaa ttattggata
    11641 aggtgggcct acctgctaaa gattatcttg atcgttaccc aagtgattta tcgggaggtg
    11701 aacagcaacg tattggtatt gtacgtgcta tcatttctca tcctaaaatt ctattgatgg
    11761 atgaaccatt ttcagcctta gatcctattt cacgtaaaca attgcaagag ttaatgttga
    11821 gtcttcacaa ggaatttgac atgacgattg tatttgtgac acatgatatt gatgaggcca
    11881 ttaaattagg agaccgcgta gctattttaa atgagggaga aattgtgcaa ctggatcgcc
    11941 cagaaatgat taagacccac cctgctaatg cttttgtggt caatttattt ggaggtgatg
    12001 agcatgccta gtttgtttgt aactttccaa aaccgtttta atgaatggct ggcggctctg
    12061 ggggaacacc tgcaaatttc ccttttatct cttatgatcg ccttgctaat aggtgtgcct
    12121 ttagcagccc ttctcagtcg cagcaaacgt tggtcagaca ttatgttaca ggtaacaggt
    12181 gtttttcaaa ccattccctc actggctttg cttggtcttt tcatcccttt aatgggaatt
    12241 ggaacgttgc ctgcagtgac agctttagtt atctatgcga tttttccgat tttacaaaac
    12301 accatcacag gattaaatgg tattgaccca agtcttgtgg aagcaggaat agcttttggg
    12361 atgaccaaat gggagcggtt aaaaacgttt gagattccaa ttgccatgcc tgtcattatg
    12421 tcaggtgtgc gaacgtcagc agtcatgatt atcggcacag ctactttagc ttccttgata
    12481 ggagccggtg gacttggctc tttcatctta ttggggatcg atcgtaataa tgctaacctg
    12541 attctgatag gggctatttc ttcagctctg ctagctatta ttttcaatag tttgttacag
    12601 taccttgaga aagcttcctt gcgacggatt atgattagtt ttggaatcac cttacttgca
    12661 ttgctagcat cgtatactcc tatggcgctt agtcagtttt caaaaggaaa agatacagtg
    12721 gttattgccg gtaaattggg agcagagccc gatattctga ttaatctcta taaggaatta
    12781 attgaagacc aatcagatat aagtgttgag ttgaaatcta attttgggaa aactagcttc
    12841 ttatatgaag cccttaaatc tggagatatt gatatctatc ctgaatttac aggaaccata
    12901 acatcaagtc ttttacgcga caaaccacct ttgtctaatg accctaagca ggtctatgag
    12961 gatgctaaaa aaggcattgc taagcaagat aaactgaccc ttcttaagcc atttgcttac
    13021 caaaatacgt atgctgttgc tatgccagaa aaattggcta aggaatatca gattgaaacc
    13081 atttctgatt taaaagcgca tgctgatact ttaaaggctg gttttactct ggaatttaag
    13141 gacagagcag atggctataa gggaatgcaa tctcaatatg gattacagct atctgtggcg
    13201 actatggagc cagctcttcg ttatcaagca attcaatcag gagatatcca agtaacagat
    13261 gcttactcta cggatgctga aattacgaaa taccatttga aagttttaaa ggatgataaa
    13321 cagttgtttc caccttatca gggagctcct ttgatgaaaa cttccttatt aacaaaacat
    13381 ccagaattaa aaggcattct taatcaatta gcgggaaaaa ttactgaaaa agagatgcag
    13441 gacatgaact acgaggtatc tgttaaagga gcagatgcta ataaggtcgc tcgagattat
    13501 ctgttgaaaa caggcttaat ccagaaataa acagaaatgt tggtccgtag gactggcatt
    13561 ttttcgtctc ttaagttcaa gaagtaacaa ttcataaata caaaaaccga actttaaaat
    13621 taaaaatagc atataaattt gacaaaatat aaacaaataa gtaatctata aaatgaaagg
    13681 taagttttta cctaaagata cctctaatca tcagaggtca taggaagatt attttgtata
    13741 gaggacttag agaagaaggt gagaactgac ttattttctt tcatctgtgc taaaagagga
    13801 gaaacttatg tttaatgaca tccctgtatt tgattatgaa gatattcaac tgattcctaa
    13861 caagtgcatt attactagtc gttcacaagc agatacaagt gtgacactcg gaaaatacca
    13921 gttcaagcta ccagttatcc cagcaaatat gcaaaccatt attgatgaaa caattgctga
    13981 gcagttggca aaagagggtt atttttatat tatgcatcgt tttgatgaag atagccgcaa
    14041 accttttatc aaacgcatgc atgaacaagg cttgattgca tccatctctg ttggggttaa
    14101 agcttacgaa tatgaatttg tgacttcttt gaaagaggat actcctgagt ttatcaccat
    14161 tgatattgct catggtcatg ctaacagtgt tattgatatg attaagcata tcaaaactga
    14221 attaccagaa acatttgtca ttgctggaaa tgttggtacg ccagaagctg tacgagaact
    14281 cgaaaatgca ggtgctgatg ctactaaagt aggcatcggt ccaggcaaag tatgtatcac
    14341 taaagttaaa acaggtttcg gtacaggtgg ttggcagtta tcagcactgc gctggtgcgc
    14401 aaaggcagct cgtaagccta tcattgctga tggtgggatt cgcacacatg gtgatatcgc
    14461 taaatccatc cgctttggag ctagtatggt catgattggt tcgctttttg cagggcatat
    14521 tgaaagtcct ggaaaaacag tagaagtgaa tggtgaaacg tttaaagaat attatggctc
    14581 ggcgtcagca tatcaaaaag gcgagcataa aaatgtagaa ggcaaaaaaa tcttattgcc
    14641 tacaaaaggt cacttatcag ataccctgac cgaaatgcaa caggatttgc aatcgtccat
    14701 ttcttacgcg ggtggtaaag atttagacag tttgcgtcat gttgattatg ttatcgtcaa
    14761 aaattctatt tggaatggtg attccattta aatgatatgg agttagctag gaccagtaaa
    14821 gaatttttta gcttaatgct ggagatgctt ttatcatatc tctgtaggta ttgaaaaaaa
    14881 taagaaacat ggtaaaatag taaattatca taatgaattc aataatgaca tacttattta
    14941 tgctgtgaat tggcgcagcg tctctacaag acaccttaat gtctaacaat aagtaagctt
    15001 ttaggcttgc ttggttttta accttgcaaa gtgagaaact cttatagttt ctggctttgc
    15061 ggcaggcttt ttctatttga atcaaaagga gatttatgca gttacttgaa gaacgcatct
    15121 taacagatgg caatattcta ggagagaata ttctaaaggt agataatttt ttaactcatc
    15181 aagttgatta ccggttgatg aaagcaattg gtaaagtgtt tgctcaaaaa tatgctgagg
    15241 ctggcattac aaaagtggtt acaatcgaag cttcaggtat tgcaccagcc gtatacgctg
    15301 cagaagcaat ggatgttcct atgatttttg cgaaaaaaca taaaaacatt accatgacag
    15361 aaggcatttt gacagcagaa gtttattctt tcactaaaca agtgacgagc acggtgtcta
    15421 tcgctggtaa attcctatct aaagaagaca aggttttgat tattgatgac tttttagcta
    15481 atggtcaggc agccaaaggc ttgatcgaga ttattggtca agcaggggca caagtcgtcg
    15541 gcgttggtat tgtgattgag aaatctttcc aagatggtcg tcgattgatt gaagatatgg
    15601 gcattgaagt gacctcatta gcacgtatta aaaactttga aaatggtaat ctaaacttct
    15661 tggaggctga cgcataatga cacattcaac aaagcaggaa cattctcact cgcaatcagc
    15721 tgtccttggc ttacagcatg tgctttcgat gtatgccgga tctattttag taccaattat
    15781 gatcgcaggt gctttaggtt attccgctag agagttgacc tacctgattt cgacagatat
    15841 tttcatgtgt ggtgtggcta cttttttaca gttaaagtta accaagcata caggagtagg
    15901 gttaccagtt gttttaggct gtgcttttca atcagtggca cctctatcca ttattggagc
    15961 gcaacaaggt tcaagtgcca tgtttggagc cctcattgcg tcaggaattt atgtcatttt
    16021 agtggcaggt attttttcta agattgctcg tttcttccca ccaattgtta caggatcggt
    16081 cattaccgtt attggcttaa gtctcgtagg tgttgctatg gggaatatgg gagataacgt
    16141 caaagagcct acggcacaaa gcatgatgtt atcattgttg acgattgtca ttattctttt
    16201 agtccaaaaa tttaccaaag gttttgtgaa atccatttcc attttgattg ggcttgtagc
    16261 gggaactttg gtttcagcta tgatgggatt agtagataca actcctgttg tagaggcttc
    16321 ttggattcat gtgccaaccc cattttattt tggcatgcca acttttgaaa tcacttctat
    16381 tgtgatgatg tgtatcatcg caacggtttc tatggttgaa tcaacaggtg tctacttagc
    16441 gctttcagat ttgactaatg atcaattaga tgaaaaacgt ttgcgcaatg gttatcgctc
    16501 agaagggatc gcagtctttc tcggtgggtt atttaatacc ttcccttaca ctggtttttc
    16561 tcaaaacgtt ggacttgtcc aaatctcagg tattaaaacc cgtcgtccga tttactacgc
    16621 agcaggtatc cttgtggtca ttggtctact ccctaaattt ggagcaatgg cacaaatgat
    16681 tccaagccca gttcttggtg gagccatgct tgttctcttt ggtatggttg ctcttcaagg
    16741 aatgcaaatg cttaatcgtg ttgatttcca aaagaacgag tataatttta ttattgctgc
    16801 tgtttccatt tcagcaggct tagggtttaa tggcaccaat ctttttacta gcttaccaga
    16861 gacagctcaa atgttcttaa cgaatggtat tgtgattgcc actttgacat ctgttgtctt
    16921 aaatttagtt ttaaatggta aagacaaaca agatgaataa ttaaaaaacg gctaattgag
    16981 ccgttttttc tgtgatcagt tttgagcaaa ccgttaaccc cttttaatga tagtatggtt
    17041 gaaaatagtg tctcaaacca tttgacataa ggacatggtg ctttcttgtt actagaagac
    17101 cttcaatatt atcaaaggtg tttaaaagtg tgataatcat tgagctatca agaccaaata
    17161 aacgggtagc ccatatgtca caataaaaag aagaaggagc catgaccgtt aagctaagca
    17221 tatctgtttc tatagggtag cctgtctgac gatctaagat atgatgatac tgtttccctt
    17281 tggctgtaaa ctgcctttca taaattccag aagtcacaac agagtgattg ttaaccttga
    17341 tgacaccaag atgttgccca cgtttagcat ctggtttttg aatgccaatt cgaaaagtct
    17401 tgtcagggct tttcggatta ggtccatgaa ctaagacgtt tccacctaaa ttaataaggg
    17461 cagagtcaat accatcttca atcaggtagg ccataatctt atcagtaata taaccttttg
    17521 ctaaggctcc taagtctaaa gccattccta cttgttgtaa aaagacagtc tgttttttgt
    17581 catctataag aacctgtcta ggatctgtta gagctaactg ttgtgagata aggttatgac
    17641 taggcactct agcatcttca aatccaattc gccaggcttg aacaagtggc ccaatggcga
    17701 tattaagatt acttggtgtt gacaagctat aagctttacc aatttggatt aggttaaata
    17761 aatcagagtg aacgctgacg ggtttaacac cagccgcctg attaatagcc atcaattcag
    17821 agtttgaatc attagctgaa aaacgatttt tgtaagtata taataagtca atgactctac
    17881 ttagttgttg gcaagctttg tcagattcga tctgaatatc aataactgtt cccattagct
    17941 ttaattgttg cgtaacaaac ataattagtc ctctttttag cagaataccc ccactaagga
    18001 gtgggggaag gtcattatga tttttgtttc atttcacctt gaggatagta agttccttca
    18061 ggcatatcgt tgataaaaac atggatattt tctttaggtg cttttgcaat gcgtgagact
    18121 acttcggtaa cctcgcgagc taattgattt ttttgttctt gtgagcgtcc ctcaaacaag
    18181 tcaattgtta caaatggcat aatgttactc ctttatgtta ttgggcatca ttgtaacata
    18241 atgctgtgaa aaagtataca ctgttttcaa tggctgggaa aacttcagcc tttgtggtaa
    18301 aataggtaga atactataga aagtaggatt ttccgctttg gctcaactct attataaata
    18361 tgggacaatg aattctggta aaaccattga aattttaaaa gttgctcata actatgaaga
    18421 acaaggcaaa cctgttgtca ttatgacaag tgctcttgat acacgtgatg gttttggcat
    18481 cgtctcaagc cgtattggta tgcgacgaga agctattccc atttcaaatg acatggatat
    18541 tttcacattt attgcccaat tggaggaaaa accttattgt gtcctgattg acgaaagcca
    18601 atttttaagc aagcaaaatg tttatgattt ggcgcgtgtg gtggatgagc taaatgttcc
    18661 tgtcatggct tttggtttga aaaatgattt ccaaaacaat ctttttgaag gttcaaaaca
    18721 tttgctatta ttggccgata agattgatga aatcaaaaca atttgccaat actgtagtaa
    18781 gaaagcaacc atggttttaa ggacagaaaa cggaaaacct gtctatgaag gcgatcagat
    18841 acaaattggt ggtaatgaaa cctatatccc agtttgtcga aaacattatt ttaatccaga
    18901 gatttaaaag gtaatcagtt ttaaaggaga tacaaagaaa aatgaatatt tatgatcaat
    18961 tgcaggcagt tgaagatcgt tatgaagagt taggtgagtt acttagtgat ccagatgttg
    19021 tttcagatac aaagcgattt atggaattat cacgtgaaga agctaatact cgagaaactg
    19081 tcacagctta tagagaatat aagcaagtca ttcaaaccat ttcagatgct gaagaaatga
    19141 tcaaagatgc cagtggtgat cctgaattag aagaaatggc taaagaagaa cttaaagaat
    19201 caaaagcagc taaagaagag tatgaagaaa aattaaaaat tcttctatta cctaaagatc
    19261 ctaacgatga taaaaatatt attttagaaa ttcgtggtgc tgctggtggc gatgaggcag
    19321 cgctttttgc tggtgatctt ttaacaatgt atcaaaaata tgctgaaact caaggatggc
    19381 gttttgaagt tatggaatca tccgttaatg gtgttggtgg tattaaagaa gtggttgcca
    19441 tggtttctgg tcagtcagtt tattctaagc ttaaatatga atcaggagct catcgtgttc
    19501 aacgtgtccc agtgacagag agtcagggtc gtgttcatac ttcaactgca actgttttgg
    19561 taatgccaga agttgaagaa gtagaatacg acattgatcc taaagactta cgtattgata
    19621 tttaccacgc gtctggtgct ggtggtcaga acgtcaataa agttgctact gcagttcgta
    19681 tggtacacat tcctacagga atcaaagttg aaatgcaaga agagcgtact cagcaaaaaa
    19741 accgtgataa agcgatgaaa atcattcgtg ctcgtgttgc tgaccatttt gcgcaaattg
    19801 ctcaagatga gcaagatgct gaacgtaaat caacagttgg tactggtgat cgttcagaac
    19861 gtattcgtac ttataatttc ccacaaaatc gtgtaacaga tcatcgtatt ggtttgacac
    19921 ttcaaaaatt agatactatt ttatctggaa aaatggatga agttattgat gcactcgtta
    19981 tgtatgatca gacaaagaaa ttagaatctc tcaataacta atgaactatg ctacattaat
    20041 cagaacttat gaagataaac tagaacaaat agatgaggat cgcgaaaatc tcgcctatgt
    20101 ttttagagaa atcaaagaat ggtcaagtct agatatgttg attcaccaaa atcaagctgt
    20161 gactcctgaa gatgctgttc ttttggaaca tattttctgt tctctaagtc agcatttatc
    20221 tcctcaatat attacaggta atgcttattt tcgtgatttg aagcttgcag tcgacaagcg
    20281 tgtattaatt ccaaggccag aaacagaaga attagttgac atgattttag ctgaaaatct
    20341 tgatgcaccg ttgaatgttt tagatattgg tacaggtagt ggagcgattg ctatttctct
    20401 caaaaaagaa aggtctaact ggcaagtaac ggcatctgat atttctagag ctgctcttga
    20461 cttggcaaaa gccaatgctg atgcttacca gcttgatata acgtttattg aatcagatgt
    20521 ttttagtctc atttcaggaa catttgatat tattgtgtca aatcctccct acatatccta
    20581 cgaggataag gaagaagtta gtctaaatgt tttgcaatca gagcctcatt tggcactttt
    20641 tgctaaagaa aatggctatg ctatttaccg taagattatt gaacaagctg acaattactt
    20701 agctaaggag gggaagcttt actttgaaat tggttataag caagctgaag gtataaaaga
    20761 tatgttacaa gcctattttc ctcaaagaca tatacgagtc gtaacggata tatttggtaa
    20821 agaaaggatg gtggttgttg attatggagt atctagctag tatcattgaa tcaggtgatg
    20881 cccttgtttt gccaacagaa acggtttatg gtcttttcgc caaggcttta gatgaaaaag
    20941 cagtaaatgc tgtttatgac ttaaaacaaa gaccccgaga taaagcaatg aaccttaatg
    21001 tggctgattt taatagtatc ttagcctttt caaaagaaca gccgagatac ctcaagaaat
    21061 tataccaagc ctttttacca ggtccgttaa cgattatttt aaaagctaat gaccaggttc
    21121 cttattggat taattcgggt ctttcaacgg ttggttttcg cttaccaaat catccaatta
    21181 ccgcagcttt aattcaaaaa acaggccctt taattggtcc ttctgcaaat ttatctggca
    21241 aagctagtgg tcgagttttt gatcatatta tgcaagattt tgactttcaa gtgtttggtt
    21301 atgcagatga tccttttcta acaggtaagg attcaaccat cttagactta tcaggtgagc
    21361 gtgctgtgat tttacgtcaa ggtgctatca ccaaagaaga attattagcc aacgtgcctg
    21421 aacttcgctt ttaagagagg agccgcttgg aatgttgaga ccattaagta aaacggactg
    21481 tcctatgcta caagaaatta acgccaaagc ccttggctat ttagtttcgc ttgacttgtt
    21541 agaaaggcaa tatgaacgat tgattgagga ttgccatcac tattttttag cttatgccga
    21601 caaggatacc aatcaattat taggctatgt tcacgctgaa cgttatgaga ccctttatgc
    21661 ttctgatggt cttaatctct tgggcttggc tgttttacca gcctatcaga gaaggggaat
    21721 tgggagtgcc ttactaaggg ccctggaatc ccaagctagg caggaaggca ttgcctttat
    21781 tcgcctcaat tctgccagtc atcgtaaaga agcgcatgct ttttaccgaa acctcgacta
    21841 tgcagatgat aaaacacaat tacgattcat caaaaactta caaggagatg acaatgattt
    21901 ttgataaagg taatgttgaa gactttgata aagagctttg ggatgccatt catgctgaag
    21961 aagaaagaca agaacatcat atcgaattga ttgcatctga aaacatggtt tcaaaagctg
    22021 tcatggcagc tcaaggttct gttttaacca ataagtatgc agaaggctat ccaggtaatc
    22081 gctattatgg tggaacagaa tgtgtggata ttgtcgaaac gcttgctatt gaacgtgcta
    22141 agaaactttt cggtgccgca tttgccaatg ttcaagccca ttccggaagt caagccaatg
    22201 cagcagctta tatggcctta attgaggctg gtgataccgt attaggaatg gatttggctg
    22261 caggtggtca tctcacgcat ggctctccag taaatttttc tggaaaaact taccattttg
    22321 tgggttattc agtagatgct gatactgaaa tgttaaatta tgaggcgatt ttagaacaag
    22381 caaaggcggt ccagccaaag cttatcgttg caggggcttc ggcctactct agaagcattg
    22441 attttgaaaa gtttcgtgcc attgctgatc acgtaggtgc ttacttaatg gtggacatgg
    22501 ctcacatcgc tggccttgta gcagcaggtg tgcacccgag tcctgtccct tatgcgcata
    22561 ttgtgacgtc aacaacccat aaaaccttac gtggtcctcg tggaggcttg atattaacca
    22621 atgacgaagc tcttgctaaa aagattaatt cggccgtttt ccctggttta caaggaggac
    22681 ctctggaaca cgtgattgct gccaaagcgg ttgccttcaa agaagccttg gatccagcct
    22741 ttaaagacta tgcacaagct attattgata atactgcggc tatggcagca gtttttgcac
    22801 aagatgatcg tttccgtctg atctcaggtg gtacagataa tcatgtcttt ttagtagatg
    22861 tcactaaggt tattgctaat ggtaaactag cgcaaaatct tctggatgag gttaatatta
    22921 cccttaataa aaatgccatt ccttttgaaa ccttgtcgcc atttaaaacc tcaggtattc
    22981 gcattggttg tgctgccata accagccgtg gtatgggtgt taaagagagt cagaccattg
    23041 cccgtcttat catcaaagcc ttggttaatc atgatcaaga aactattctt gaagaagtcc
    23101 gtcaggaagt gcgtcagtta accgatgctt tcccactcta taaaaagtaa ggaatcatgt
    23161 tagatagtta tataaaacgt attgtcattc atcaattttc tcccaatgac actgagttac
    23221 tgttatcaga tcgtttagtg agcattacac cacgaattga tgaatatttc cggaaaaaat
    23281 tggctaaagt gttctcggat gaagccaaac ggggtcagtt tgaggctaat aatacctttt
    23341 ttacaaccat tggtgatgat ttgttggaaa cgtctgttac cattgcccag ttatggaagg
    23401 aagcctttgt tatttcagag gatcaaaaaa ccaatgattt agtctttgtc cagtttgata
    23461 aggatggcga accctttttt gctttcttgc gaattgcttt gaaagaacag tttgctcacc
    23521 tttctgacaa ttatgaacat ccatttacgg tgacgcagaa taatctgccg agtcccaccc
    23581 agacaccaga tgaagcacta gtcattaatc tcaaatctgg tcagtactac ttgattgaaa
    23641 agcgtgtgaa gcataatggc agttttgcta attatttttc agaacacctc ttgaaagtta
    23701 cacctgagca atctgttaaa aagtctatca aaatgataga acaaaccgct caaaaaattg
    23761 cagagcattt taatcaagat gattttactt ttcagtcaaa gatgaaatcc actcttttta
    23821 agcagttaga agcagacgac gttttatcac cagaaaaatt agctgaccaa ctctttgatg
    23881 ataatttaac agcccgttta acctttgtgg atcaagtcaa agaagtcatt ccagaaccta
    23941 taaaaattag cgatattgat cattctagac agataaaaaa actagaaaat caaaagctat
    24001 cgttatcaaa cgggatagaa ttaacagtac caaatgccat ttatcaggat gctgaagcgg
    24061 ttgaattttt gttaaatgat gatgggactt attcaatctt gattaaaaat atagaggata
    24121 ttaaaaccaa atagatgttt agacttttaa agcgtgcctg cagttttctt cttctttttg
    24181 tcatttatca atcctttgtt attcatcaca atgttcaacg tgttttggca tataagccta
    24241 tggttgagaa aacattagca gaaaatgata caaaggcaaa tgtagactta gtcttagcta
    24301 tgatatacac cgagacaaaa ggaggagaag cagatgtcat gcaatccagt gaaagcagtt
    24361 caggacaaaa aaactcgatt acagatagtc aggccagtat tgagcacggg gtgaatttac
    24421 tgtctcataa tcttgctcta gctgaggaag caggagtaga ttcttggacg gctgttcagg
    24481 cctataattt tggaacagct tatattgatt atattgctaa acatggaggt caaaataccg
    24541 ttgatttagc gactacctat tccaaaaccg ttgtggcgcc aagcctaggc aacactagtg
    24601 gtcaaaccta tttttattac caccccctcg ccttgatttc tggaggtaag ctttataaga
    24661 atggcggcaa tatctattac tcacgagaag ttcatttcaa tctttattta attgaactga
    24721 tgagcctttt ttagaaagtt atcatgaaac gattacgtcc atatttgaaa gggtacctaa
    24781 aagaaagtat cttaggtcct ctttttaaat tattagaagc tttatttgaa ttattagtcc
    24841 ctttgttaat tgctaacatg attgatatat cgattagtca acacaacagc cagggaattt
    24901 tgagggttgt tttaacatta tttggtttag caaccattgg cttattgctt tccgttacag
    24961 cccagtattt ttcttcgaaa gcagctgttg gttttacaag acaaatgaca gatgatttgt
    25021 ttaaaaaaat catgtttttg agcaaggagg accaagacca tcttggttat gctagtctgt
    25081 tatcacgatt gaccagtgat agttttcaaa ttcaaactgg tatcaatcaa tttttgcgtc
    25141 tttttctaag ggcccctatt atcgtatgtg gtgctacggt aatggcttat tggattagtc
    25201 caagtctaac cctatggttt gtgatgatgg tgattgtctt actaacactt gtttttgtta
    25261 tgtcacattt attaggtccc ctttatctct taatccgccg agaaacagat cacttggttc
    25321 gtttgactag ccaacagtta caaggaatcc gagtaattaa ggcttttaat caaacccaaa
    25381 aagaactcca agcatttaag cagcaaaata tgctcttaag tcgccaccaa tatcaagctg
    25441 ctaccctagc caatgtcttg aatcctatga cttttttagt ggtcaatctt accctgttaa
    25501 tcttgatttg gcaaggaagt tggcaagtag ctcatagatc gcttagtcag ggcatgttgg
    25561 ttgctttaat taattacctc ttgcagattt tggcagaact tttgaaaatg accatgttga
    25621 tgggaaccat caatcaaagt gtaacagccg caaaacggat taatcaggtg tttgttttag
    25681 ctgatgaagc gcctttgccc tcacttaaag atggtcctat ttcaactcat ctgttgacca
    25741 tccggcactt gacctttact tatccaggag cagcagagcc aagtctgtat gatattcagt
    25801 taagtgctga ccagggagaa tggattggca tcattggtgg tactggagca ggcaaaacga
    25861 ctttgattga cttgatctgc caaacttatt caccatatag tggtgagatt agtcttaatt
    25921 ggcaaggaga agtgccaaaa acactaaccg agtggcgaaa tgtgattgct cttgttcctc
    25981 aaaaagctca attatttaaa ggaacgatta gaagtaacct cctactggga caatcaatgc
    26041 ctattagtga tgaggaactg tggcgggctc ttgaattggc tcaagcaaaa gagtttgtcg
    26101 ctgccttacc agaacaatta gaggcacctg ttgaagcctt cggtcgtcat ttttcaggag
    26161 ggcaacggca acgtctagct attgccagag cacttctgaa gccaaaaccc attttgattt
    26221 tggatgatgc cagttccgcc ttagacaatg agactcgagg acgacttttt aaagctctaa
    26281 aagaagagtt atcagatgtt ttagtgattc tagtcacgca atccatcaag aatttgcagt
    26341 ttgctgataa gattttagtg ttggaacagg gccatcaatt ggattttgcc agtcatgacc
    26401 agttaaaagt aagcaatgca ctttatcaag aaatgctagc gctttacgtg aagggggagc
    26461 aaaaatgatt aaaacagatc atcacctcct aaagcgaatg cttcacgatt tgttaaaaaa
    26521 acctctacct gtttgtattc tcgtgatagc tagttttgta caagttggtt taagtgttta
    26581 cttgcctgtt cttatcggta aagccgttga tatgagtttg tcagtcaatt cttggcaaac
    26641 tttaaaatgg ctgttggggc aaatgttagt tgttattgtg gtcaacacat tgattcaatg
    26701 ggtgatgcct cttgtctata gtcgtttgct atatcaatat agccagcaat tgaaagataa
    26761 gcttttggaa aaaattcatc gtcttccttt tgcatatcta gatcgtcaaa ccattggaga
    26821 tttggttagt cgagtgataa ccgacactga gcaactgatc aatggtctac aaatggtttt
    26881 taaccagttt atacttggac tattgacgat tctgtgtacc attatagcta tggcacagat
    26941 tgactggttc atgttaatct tggttttggt gttaacacca agctccctct ttttagctcg
    27001 ttttattgct caaaagagtt ttcattatgc acaagcacag accaaaagca gaggaaattt
    27061 agctcagttt actgaagaaa tccttcgtca agaaggtttg gttcaactgt ttaatgctca
    27121 agagcagtct atctgtgatt atcatgtttt aaataaaacc tattgcgagg cttcacaaaa
    27181 agtcattttt tacgcctcaa cagtcaatcc agccactcgc tttattaata gtgtcattta
    27241 tgctttactg gcaggtttag gggctgttcg tatcatggct ggactttttt cagtaggtca
    27301 gctaaccact tttttaaatg ttgttgtcca atataccaaa cctttcaacg atatttcatc
    27361 tgtcttggca gagatacaga gttctttagc ttgtgcgcaa aggctttatg accttttaga
    27421 tattgaaata aaagaggaag agcacttttt aacatttaag gcatcagcgg ttaaggggca
    27481 aattgacttt gaagaagtaa gtttttctta tcaaaaagac aggcccttac tgaaggatat
    27541 taatttttct gttcctgcgg gttccaaggt agcgattgta gggcctacag gtgcaggcaa
    27601 atcgacttta atcaatttac tcatgcgctt ttatgaactt gatgctggta gcatcaagtt
    27661 agataaagtt cctattaagt gttatgctaa ggaagaactt aggtccatta ctggcatggt
    27721 attgcaagaa acctggttga aagatgcgac tgttcatgag ttgattgctt acggcagtga
    27781 agaggctagc cgtggtgaag tagtggcagc agccaaagca gctcatgtac acttctttat
    27841 tatgcaactt cctaagactt atgatactta cttaagtgct tctgatgatg ctttgtccca
    27901 agggcagctc cagttattag ctattgccag aatgtttttg aaaaaaccaa aagtcttgat
    27961 tctagatgaa gccacctcct ctattgatat tagaacagaa gctgttattc aagaggcact
    28021 aaaagaacgg accagcttta tcattgccca tcgtttatca acgattcaat cagctgattt
    28081 gattcttgtt atggatcaag gtcgattggt tgagtgggga acacatgcca gcttaatgtc
    28141 aaaaaacgga tgttatgcta gattacaaaa gatagaataa agttcgtctt ttaacaaagg
    28201 tgaacttttt aactcttcct aaagttagtt aattaacaaa ctttaaactg ttatataaaa
    28261 aaataacagc gaaaaagcgg acgatctttt tttataagtg agaaaaaaca gttgactaaa
    28321 gaagaaataa ctcaaaaaag tgagcaatat atttggaagc gttttttgac tgtggtataa
    28381 tagagcccta tataatattg tgaaatgagg aacaaaatat atgagtaaaa tcgttgttgt
    28441 tggtgcaaac catgctggta cggcctgtat caagactatg ttaacaaact acggtgatgc
    28501 taatgagatt gttgtatttg accaaaactc aaatatttca tttttaggct gtggtatggc
    28561 actttggatt ggtgagcaaa ttgctggacc agaaggactt ttctattcag ataaagaaga
    28621 attagagtct ttaggggcta aagtttacat ggaatcacct gttcaatcaa tcgactacga
    28681 tgccaaaaca gtgacagcgc ttgttgatgg taaaaaccac gtggaaactt acgacaagtt
    28741 gatttttgca actggctcac aacctatctt accaccgatt aaaggtgccg aaatcaaaga
    28801 aggatcactt gaatttgaag caactcttga aaatcttcaa tttgtgaagt tataccaaaa
    28861 ctcagctgat gtgattgcaa agcttgaaaa caaagacatt aaacgtgtag ccgtagttgg
    28921 tgctggttac attggtgttg agttagctga agctttccaa cgcaaaggca aagaagtggt
    28981 tctgattgat gtcgtggaca cttgcttggc aggttattac gaccgtgatt tgactgactt
    29041 aatggctaaa aacatggaag aacatggtat tcaactagcc tttggtgaaa cagttaaaga
    29101 agtagctggt aatggtaagg ttgaaaagat cattactgac aaaaatgagt acgatgtgga
    29161 tatggttatc ctcgccgttg gtttccgtcc aaacacaact cttggaaatg gtaagattga
    29221 tcttttccgt aatggtgctt tccttgtcaa taaacgccaa gaaacttcta ttccaggtgt
    29281 ttatgctatc ggtgactgtg caactatcta cgataatgct actcgcgata caaactacat
    29341 tgctttagct tcaaatgctg tccgtacagg aattgtagca gcacataatg cttgtggtac
    29401 agaccttgaa ggaatcggtg tccaaggctc aaacggtatt tccatttacg gcttgcacat
    29461 ggtatcaact ggtttgactc ttgaaaaagc taaacgactt ggttttgatg ctgcagtgac
    29521 tgagtatact gataaccaaa aacctgaatt tatcgaacac ggtaacttcc cagtaaccat
    29581 taagattgtt tacgataaag actcacgtcg tatcttgggt gctcaaatgg cagcccgtga
    29641 agatgtgtca atgggaattc acatgttctc acttgctatc caagaaggcg taaccattga
    29701 aaagttggca ttaactgata ttttcttctt accacatttc aacaaacctt acaactacat
    29761 cacaatggca gcacttggtg ccaaagacta gtatctgata ggaaaaagcc agagcagttc
    29821 agcagcactg gcttttttgc tttttaattg ttgcaacctg aaaagttcta aacttatgat
    29881 tatcctctta tagcacgttg gaaaaggaat atccggcaaa acaaaaagag accaaagtct
    29941 cttttgtgat tagtttttag cagcagaagc aaattcttcc ttagcaaagg cttcatcaat
    30001 gatagctttt aattgatttg cagaggcttg cattttttgc aattcagcat cgttaagtgg
    30061 aatgtttact ggacgaacaa ttccatacgc tccaacgata gctggttgac caatatagca
    30121 atcttcaaca ccttcgtatt ggccttcttg gaaaacagaa agtggaagaa cagcattttc
    30181 atcatcaaga atagcttttg taatacgagc tagggcaact gcaataccgt agaaagtagc
    30241 acctttttta ttgatgattg agtaagcagc atcacgtaca gaaatgaaaa gatcaactag
    30301 gccttgctca tcaatgtcac gattagcttg gagccagtcg taaagaccta caccagcaac
    30361 gttagcgtgt gaccaaacag caaattcaga gtcaccgtgt tctcccatga tgtaagcgtg
    30421 aaccgaacgc gcatcaacac cgattttagc agccagagct tgacggaaac gggctgaatc
    30481 tagagatgta cctgatccaa taacacgctc tttagggaaa cctgagaatt tccatgttga
    30541 gtaagtcaaa acgtcaactg ggttagcagc aacaagaaag attcctttga aaccagatgc
    30601 aacgatttgt gtaacaacct ctttattgat acgaaggttt ttttcaacaa ggtcaaggcg
    30661 tgtttcacct ggtttttgag gagcaccagc tgttaagaca acaagatcag cgtcatgaca
    30721 gtctgagtag tcagctgcat agattttttt aggtgatgta aaagctagag cgtggcttaa
    30781 atcttctgca tctccttgag ttttttcttt aaaaatatca ataataccaa gttcttgagc
    30841 aatattttgt gttaccaatg caaaagcgta tgatgaaccg acggcaccat caccgaccaa
    30901 gattactttt ttgtgttgtt tagttgcagt catttctaaa catctcctta attttattag
    30961 agcaaaagct catacggtct tattttaaca tattgataat tgtttgtcat tgaattcaga
    31021 aaaataatga aaatagtttc ctgataacgc ttccaataa
//
LOCUS       DAUCXI010000020        28695 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.020, whole genome shotgun sequence.
ACCESSION   DAUCXI010000020 DAUCXI010000000
VERSION     DAUCXI010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28695
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.020"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            665..901
                     /locus_tag="VGY43_000974"
     CDS             665..901
                     /locus_tag="VGY43_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEQ4302170.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGAGEGFSMWAPTPCDVLAEDWIEVND"
     gene            894..1592
                     /locus_tag="VGY43_000975"
     CDS             894..1592
                     /locus_tag="VGY43_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEQ4302171.1"
                     /translation="MTKVVLVTGCASGIGYAQARYFLRQGYHVYGVDKSDKPDLNGNF
                     HFIKLDLSSELSPLFKVVPSVDIVCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTKPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            1668..2627
                     /locus_tag="VGY43_000976"
     CDS             1668..2627
                     /locus_tag="VGY43_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ4302172.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLKTAKDLA
                     KAYHMPLATSEYEAVLGNEEIDTVYIGLPNHLHFAYAKEALLAGKHVICEKPFTMTAG
                     ELDELVIIAKKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNYSQYSSRYDAF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANMDKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKSTIQGNKGSLAVLGATNTLPQIELVIYGQKPQVINHNKH
                     DHRMYEEFVAFRDMIDQRDFEKVNQALEHSRAVMAVLERAVHS"
     gene            2960..4297
                     /locus_tag="VGY43_000977"
     CDS             2960..4297
                     /locus_tag="VGY43_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ4302173.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIV
                     FVYERLTATGAPNYFLLLVIAGILGSLIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            4470..5852
                     /gene="glmU"
                     /locus_tag="VGY43_000978"
     CDS             4470..5852
                     /gene="glmU"
                     /locus_tag="VGY43_000978"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEQ4302174.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKAVTVIGHKSEKVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLKSLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILR
                     DFNESLGVNDRVALATAETVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGQGSIITNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEVGDNALTAAGSTISKTVPADSIVIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            5883..6437
                     /locus_tag="VGY43_000979"
     CDS             5883..6437
                     /locus_tag="VGY43_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ4302175.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKIVLVKQYRKAIESVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            6437..6688
                     /locus_tag="VGY43_000980"
     CDS             6437..6688
                     /locus_tag="VGY43_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302176.1"
                     /translation="MGRPLLTDDIIEKARRMETFEPDDAVDFDTKVMTLPEKDEKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            6707..7402
                     /locus_tag="VGY43_000981"
     CDS             6707..7402
                     /locus_tag="VGY43_000981"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEQ4302177.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQILMTFLENSPV"
     gene            7553..7894
                     /locus_tag="VGY43_000982"
     CDS             7553..7894
                     /locus_tag="VGY43_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302178.1"
                     /translation="MTLKKHYYLLSLLALVTVGAAFNTSQSVSAQVYSNGGYRQGLTD
                     EKSHLQYSKDNAKLQLRNILNGYQSDLGRNYSSYYYYNLRTVMGLSSEQEIEKYYEEL
                     KNKLHDMYNHY"
     gene            complement(7993..8640)
                     /locus_tag="VGY43_000983"
     CDS             complement(7993..8640)
                     /locus_tag="VGY43_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEQ4302179.1"
                     /translation="MTPNKEDYLKCIYEIGEQEPKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDTFIDRLDKILDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLETHHLSINTELTLTQIDTFAKTYTICYGDKELVIPENIAKQLYVTAL"
     gene            8786..9718
                     /locus_tag="VGY43_000984"
     CDS             8786..9718
                     /locus_tag="VGY43_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEQ4302180.1"
                     /translation="MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            9782..10507
                     /locus_tag="VGY43_000985"
     CDS             9782..10507
                     /locus_tag="VGY43_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302181.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIEGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGNVC
                     EVFTVDTLSKAYGNHLILGKEMV"
     gene            10508..11362
                     /locus_tag="VGY43_000986"
     CDS             10508..11362
                     /locus_tag="VGY43_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEQ4302182.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLGVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(11510..12316)
                     /locus_tag="VGY43_000987"
     CDS             complement(11510..12316)
                     /locus_tag="VGY43_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEQ4302183.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPKQDITITSIDIVKDYRFKN"
     gene            12533..14938
                     /locus_tag="VGY43_000988"
     CDS             12533..14938
                     /locus_tag="VGY43_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ4302184.1"
                     /translation="MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQAIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLK
                     DDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTI
                     DLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIA
                     GYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(15008..15361)
                     /locus_tag="VGY43_000989"
     CDS             complement(15008..15361)
                     /locus_tag="VGY43_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEQ4302185.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTSLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            15605..16030
                     /gene="rplK"
                     /locus_tag="VGY43_000990"
     CDS             15605..16030
                     /gene="rplK"
                     /locus_tag="VGY43_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEQ4302186.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            16136..16825
                     /gene="rplA"
                     /locus_tag="VGY43_000991"
     CDS             16136..16825
                     /gene="rplA"
                     /locus_tag="VGY43_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEQ4302187.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            17148..17876
                     /locus_tag="VGY43_000992"
     CDS             17148..17876
                     /locus_tag="VGY43_000992"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEQ4302188.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            17906..18463
                     /gene="frr"
                     /locus_tag="VGY43_000993"
     CDS             17906..18463
                     /gene="frr"
                     /locus_tag="VGY43_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEQ4302189.1"
                     /translation="MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKATDDAIKEIDRMTAEKEKELLSV"
     gene            18571..19428
                     /locus_tag="VGY43_000994"
     CDS             18571..19428
                     /locus_tag="VGY43_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEQ4302190.1"
                     /translation="MNDLLATVITGLIKEENANDYFIQKEGFTFTLSKAEGERQIGDM
                     VTGFAYTDIKQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYIRLEVDKKDRIWGLPAEPEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKATFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            19501..20010
                     /gene="msrA"
                     /locus_tag="VGY43_000995"
     CDS             19501..20010
                     /gene="msrA"
                     /locus_tag="VGY43_000995"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEQ4302191.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPKQIAYKDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIR
                     HQFLEENWS"
     gene            20007..20222
                     /locus_tag="VGY43_000996"
     CDS             20007..20222
                     /locus_tag="VGY43_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEQ4302192.1"
                     /translation="MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            20378..21559
                     /locus_tag="VGY43_000997"
     CDS             20378..21559
                     /locus_tag="VGY43_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ4302193.1"
                     /translation="MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTEIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATTL
                     TVQAPASSPASVSHVPSSEPLPQASATSQSTVPMAPSATPSDVPTTPFASAKPDSSVT
                     ASYELTSSTNDVSTELSSESQKQPEVPQEAVPTPKAAETTEVEPKTDISEDSTSANRP
                     VPNESASEEVSSAAPAQAPAEKEETSQMLTAPAAQKAVADTTSVATSNGLSYAPNHAY
                     NPMNAGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPENSALGDQV
                     AQYAIDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFN
                     A"
     gene            21875..23647
                     /locus_tag="VGY43_000998"
     CDS             21875..23647
                     /locus_tag="VGY43_000998"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEQ4302194.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELIHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWIYWATMFAFEKWHSAVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELTPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKDNETTVWIYGLYSNSEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLM"
     gene            23806..24858
                     /locus_tag="VGY43_000999"
     CDS             23806..24858
                     /locus_tag="VGY43_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEQ4302195.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYETSSEEMKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            24904..25479
                     /locus_tag="VGY43_001000"
     CDS             24904..25479
                     /locus_tag="VGY43_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEQ4302196.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARIIIVGQAPGIV
                     AQETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            25638..26135
                     /gene="ybeY"
                     /locus_tag="VGY43_001001"
     CDS             25638..26135
                     /gene="ybeY"
                     /locus_tag="VGY43_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEQ4302197.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            26116..26523
                     /locus_tag="VGY43_001002"
     CDS             26116..26523
                     /locus_tag="VGY43_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEQ4302198.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            26643..27539
                     /gene="era"
                     /locus_tag="VGY43_001003"
     CDS             26643..27539
                     /gene="era"
                     /locus_tag="VGY43_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEQ4302199.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            27559..28035
                     /locus_tag="VGY43_001004"
     CDS             27559..28035
                     /locus_tag="VGY43_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ4302200.1"
                     /translation="MPQDYISYIRSKVGHDKIILNFAGGILTNDDGKVLMQLRGDKKT
                     WAIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
BASE COUNT         8779 a         5050 c         6293 g         8573 t
ORIGIN      
        1 aatttcagaa agattttata gaattattat tacggttttt cgattttgga aaataaaagg
       61 taccttcaag gtgactttta ttatttaagt ggcttaatga attggttaaa atctttttag
      121 tttagtaaaa ttgctattta aggttagcca cctctcgtat ggtcacagtt gatgaattat
      181 gctatagtat agacataaaa aatagttcaa attccttctt gcctgttggt ggattttgaa
      241 ctgaaagcct ctctgattgc agttggtagg cttttttgat gctttttcgt acttttttta
      301 tttattacgc taaaaaatgt tatacttgat gaagaaaaag gagagtttag aacgttaaga
      361 tacctcacag cagattgata gaggatatgg aagaaggtta gctttcccaa gagatgccgt
      421 ttgggaatgg tataacaata actggcagaa gttataagta aaacaaaaac aaattaactc
      481 agatgatttt tagacgttcc cacgcgtgtg cgaatgcgtg tgcgaattga tgttatcaat
      541 aaatccttta ataacgcctt tttcgaacag gaaacaaatt tattatccca cgcgtgtgcg
      601 aatgtgtggg cgaattaatt ggagaaaaaa tgagaaaata cgatatacaa aaaaggagaa
      661 caatatgaca tttgaagaga ttttaccagg tttaaaagcc aagaaaaaat atgtacgtac
      721 aggttggggt ggcgctgaaa attatgtgca gttgtttgat acccttgaag tggatgggaa
      781 agtactacag gcgacgcctt attttctgat tcatgttact ggtgcaggtg aaggtttttc
      841 catgtgggca ccgacaccat gtgatgtgtt agcagaggat tggatcgagg tcaatgacta
      901 aagttgtttt agtgacgggc tgtgctagtg ggattggtta tgcacaggcc cgctattttt
      961 tgagacaagg gtatcacgta tatggtgtgg ataaatcgga taaaccggac ttaaacggta
     1021 attttcactt tatcaaattg gatttatcct ctgagttatc cccactattt aaagtggtcc
     1081 ccagtgttga tattgtgtgc aatactgcag ggattttaga tgcctacaag ccacttttag
     1141 acgtcagtga tgaagaagtg gaacacctat ttgatattaa tttttttgcg acggtgaagt
     1201 taacacgtca ttatcttaga cgtatggtgg aaaagcagtc aggtgttatc atcaatatgt
     1261 gctcaatagc aagttttata gcgggtggcg gtggtgttgc ctatacgagt tctaagcatg
     1321 cccttgcggg attcacgcgc cagctggctt tggattacgc caaagatcag attcacattt
     1381 ttggtatagc accaggtgct gtcaaaaccg ctatgacggc tagcgatttt gaacctggtg
     1441 gcttagcaga ctgggtagct cgtgagacgc caattgggcg ttggactaaa ccagatgaag
     1501 ttgctgaatt aacgggattt cttgcgtcag gaaaagcgag atcaatgcaa ggtgaaattg
     1561 tcaaaattga cggtggctgg actttgaaat gatcacatgc cttagcttga gctggcgcag
     1621 taagccctag aggtgtgacg agtcaaacag tcaaaggaga tgaacaaatg aaattagcgg
     1681 ttttggggac aggtatgatt gttaaggaag ttttgcctgt cttgcagaaa attgatggta
     1741 ttgatctagt tgctatctta tcaactgtta gaagtttaaa gacagctaaa gacctcgcta
     1801 aggcatatca catgcctcta gctacgagtg aatatgaggc tgtcttaggc aatgaggaga
     1861 ttgacacggt ctatattgga ctgccaaatc acctgcattt tgcctatgcc aaggaggctc
     1921 ttctggctgg taaacatgtc atttgtgaaa agccctttac catgacagca ggagaattag
     1981 atgaactggt gataatcgct aaaaaacgaa aactcatttt gttagaagcg attacgaatc
     2041 agtatttaag caacatgacc tttatcaaag agcatcttga ccaacttggc gatatcaaaa
     2101 ttgtagagtg taattattca cagtattctt cacgctacga tgccttcaaa cgaggtgata
     2161 tcgcaccagc cttcaatcct aaaatgggtg gtggagcttt acgtgattta aacatttaca
     2221 acattcattt tgtggtagga ttatttggtc gccctaaaac ggttcaatat ttagccaata
     2281 tggacaaggg cattgacacc tcaggcatgc ttgtcatgga ctatgagcag tttaaagtgg
     2341 tgtgtatcgg ggccaaagac tgcactgcgg aaatcaaatc aaccatccaa ggtaataaag
     2401 ggtcactggc agtgcttgga gcaacaaata cccttcctca gattgagctc gttatttatg
     2461 gtcaaaaacc acaagtgatt aaccacaaca agcatgacca ccggatgtat gaagagtttg
     2521 tcgcttttag ggacatgatt gaccaaagag actttgagaa agtgaatcag gctttggaac
     2581 atagccgagc tgttatggct gtgttggagc gggctgttca ttcgtgattg taatctggta
     2641 gccattgcct tttgtgcagc tgctatggta atggttgaaa gacgtgtttt cacgagggtt
     2701 aaccccctcg tgcttttttg gtaaaaataa cttgttcagg atttgggctt tctttgtgag
     2761 atgagagatg cctgacgaat tgatttgatt aaaataatga taaagccaaa cgatttaaga
     2821 aatgaccgtt cggaaattct gtcccaaagg agctctagaa gcagtaaaat cgaatttgta
     2881 agcgttgaca ctgttgcata actctgttac actaagagaa tgtcatgaca aaaattacag
     2941 tgtaggagtt taattgttta tggaagagga ttataacaaa agagaacctg agaagtttac
     3001 gcaatttctg cgccgtcaaa aggttgtctt ttttgtcgca ttttttggtt atgtgtgtgc
     3061 ttacttggta cgcaacaatt tcaaactaat gtcaaacact attatggtcc aaaacggttg
     3121 ggacaaggct caaattgcga ccttgttatc gtgtttgacc gtttcttatg gcttagcaaa
     3181 attctatatg ggggccttag gggatcgtgt tagcttgaga aagctctttt cgatcagctt
     3241 gggtgccagc gctttaattt gtattttaat cggttttttc aatagttcaa tggtggtatt
     3301 aggaatactg ctagtcttgt gtggtgtcgt acaaggtgcc ttggcacctg cctcacaagc
     3361 catgattgcc aattattttc caaataaaac acgcggcgga gccatcgctg gatggaacat
     3421 ttctcaaaac atgggatcag ccctcttgcc attaaccatc gccttgctca ccagtatggg
     3481 cttggtggta ccagctaatg gcaatatttt acttgccttt ttaatccctg gtgttttagt
     3541 gttcttgttt gctttgtgtt gctggaagct tggcggtgat aaccctgagt ctgagggact
     3601 tgactctctt cgaacgatgt atggtgatgc gggcgagtca gctgttgcta gtgaagaaga
     3661 aaagcataac ctgtcttatt ggcaactcat ctggaaatac gttttttgta acccgtcgct
     3721 cttacttgtt gctgctgtca atgtggccct ttattttgtt cgttttggga ttgaagactg
     3781 gatgccgatc tacttgtcac aagtagccaa tatgtcagag gctcatattc attttgcgat
     3841 ttcaatgtta gagtgggtag ctattccagg ctcgctggta tttgcgtggt tagcggttcg
     3901 ttatcctaat aaaatggcca agattggggc tattgggctt tttgtgttag cggctattgt
     3961 ctttgtctat gaacgcttga ctgccacagg tgctccaaac tatttcttgt tgcttgttat
     4021 tgcaggtatt ttagggtcat tgatttatgg cccacagttg atcgtgaata ttttaacaat
     4081 taactttgtt cctttaaatg ttgcaggaac agcgattggt tttgtaggag taacagctta
     4141 tctcatcggc aatatgggag caaactggct gatgccgatt ttggcagatg gttttggctg
     4201 gttttggtca tatattgtcg ttgcagcctt atctgctttt tcagcggttg gttatttgat
     4261 tttagccaaa cgtgaggaag aaatcatcaa agattagcta ggcaaatgcc taagaaagac
     4321 agacttattg ctgaagtcct gtctttttta gtcatcacaa gccgcaaatg acactataaa
     4381 agacaagaaa atgctaggat gtttcaggaa aaaaagagaa aatatgctat aatgagaagg
     4441 tatttaaatt atatagtaag gaaaaacaaa tgacaaatta tgccattatt ttagcagcgg
     4501 gcaaagggac tcgcatgact tctgatctcc caaaagttct tcataaagta tctggactaa
     4561 ccatgcttga gcatgttttt cgtagtgtaa aagcgattag tcctgaaaaa gccgtgacgg
     4621 ttattggtca caaatcagaa aaggtacgtg ctgtcttagc agatcaatca gcctttgtcc
     4681 atcaaacaga gcagttagga actggccatg ccgtgatgat ggcagaaaca caactagaag
     4741 gactagaagg gcataccttg gtgattgcag gagatactcc cttgatcact ggagaaagcc
     4801 tgaaaagtct gattgatttt catgtgaatc ataaaaatgt cgccactatt ttaacagcta
     4861 cggctcaaga tccatttggt tatggtcgta ttgttcgcaa caaagatggc gaagtgatca
     4921 agattgttga gcaaaaagac gccaatgagt atgagcaaca attaaaagaa atcaatacag
     4981 gaacctatgt gtttgataac aagcgtctct ttgaagcgct caaatgcatc actaccaaca
     5041 atgctcaagg agagtattac ctgactgatg ttgtggctat ttttagagca aacaaagaaa
     5101 aggtaggagc ctatatcctg agagacttca atgaaagtct tggtgttaat gatcgtgtgg
     5161 ccttagcaac agctgaaaca gtgatgcgcc aacgcatcac ccaaaaacat atggtcaatg
     5221 gggtgacttt ccaaaatcct gaaaccgttt atattgaaag cgatgttgag attgctccag
     5281 acgtccttat cgaagggaat gtgaccttga aagggcgtac acatatcggc tcaggaactg
     5341 tcttgacgaa tggtacttat attgtggatt ctgaaattgg tcaaggaagt atcatcacca
     5401 actcaatgat cgaatcatct gttttagctg caggagttac ggtaggccct tacgcccacc
     5461 ttcgaccagg aacgacctta gatagggaag tccatatcgg taactttgtt gaggtcaagg
     5521 gttctcacat tggtgaaaaa acaaaggctg ggcatctgac ttatattgga aacgctcagg
     5581 ttgggtcttc agtcaatgtt ggggctggaa ccatcactgt caactacgac ggccaaaaca
     5641 aatatgaaac agtcattgga gatcacgctt ttattgggag caactcgact ctcattgcac
     5701 ctttggaagt tggagataat gctttaactg cagctggctc aacgatttct aagacagtac
     5761 cagctgatag cattgttatt ggtcgtagcc gccaagtcac aaaagaaggt tatgccaagc
     5821 gcctagcgca tcacccaagt cgaagcaaat aattcaagat ctatttagta aggaggccag
     5881 gcatgaaatt tgaagaaaaa acgcttaaga gacaaacagt ttttgatggt catattttta
     5941 aagttgttgt ggatgatgtt gaacttccca acaatctggg acaatccaag cgagaattaa
     6001 tttttcatcg tggtgccgtt gctgttttgg ctattactcc tgaacgtaag attgtccttg
     6061 tcaaacaata ccgtaaggct attgaaagtg tctcatacga gatcccagcg ggtaagctag
     6121 agattggtga ggaaggctca aagctaaaag ctgctgcacg tgagctagaa gaagaaacag
     6181 cctatacggg gacattgacg tttttgtatg aattttatac agcgattggt ttttgcaacg
     6241 aaaaaatcac acttttctta gcgacagacc taacacaagt tgccaatccc aaacctcaag
     6301 acgacgatga agttatcgag gtcttagagt tgacatatca agagtgcatg gacttagtcg
     6361 ctcaaggtaa acttgctgat gctaaaacgt tgattgcttt gcaatactat gccttacatt
     6421 ttggaggtga gcagtgatgg gaaggccatt gttgaccgat gatatcatcg aaaaagcgag
     6481 acgaatggaa acatttgagc cagatgatgc tgtagacttt gacacaaaag taatgacgct
     6541 accagaaaaa gatgaaaaag cacgcattta taaaagccgt cggattgaaa atgccaaacg
     6601 cagccaattg caatctaaat taaatgtgat tttgatagct gttatgctgt taattgccat
     6661 cttggtatat gctatctttt atctttaaaa aacgtaagga aatgatatga aaataggaat
     6721 tattgctgct atggaggagg agttgtctct gctcttagca aatctcttgg atgctcaaga
     6781 acatcaggtg ctttcaaaaa cttactatac gggtcgtttt ggcaagcatg agctcatttt
     6841 ggtacagtca ggtgttggaa aagtgatgtc tgctatgaca gttgcgatct tggttgagca
     6901 tttcaaagcc caagctatta tcaatacagg atcagcaggg gcagtcgctt cacatttagc
     6961 gattggagat gtggtggttg cagatcggtt agtgtatcat gatgtggatg ctactgcatt
     7021 tggttatgct tatggtcaaa tggctggtca accattatac tatgattgtg atccacagtt
     7081 tgtggctatc ttcaaacagg tcctaaaaca cgaaaagaca aatggccaag ttggtttgat
     7141 tgcaacagga gacagttttg ttgctggtca ggacaagatt gaccagatca aaacagcttt
     7201 tagcgacgtg ttagcagtag aaatggaagg cgcagctatt gctcaagcag cacatactgc
     7261 agggaaaccc ttcatcgtcg ttcgtgcgat gagtgatacc gcagcgcatg atgccaatat
     7321 tacttttgat caatttatta tagaagctgg caagcgttcg gcccagatat taatgacatt
     7381 tttagaaaat tcacctgttt aactcacctt atcgtgagtc aattagctgg ataatctcta
     7441 ttttaggagt ctggtcactt cttgttttga aacctaaaaa taagaattgc aatcacttga
     7501 ccaaacgcta taatgggtta aggaacgata gattactaaa aggagtctaa aaatgacact
     7561 aaaaaaacac tattatcttc tcagtctgct agctcttgta acggttggtg ctgcctttaa
     7621 cacaagccag agtgtcagtg cacaagttta tagcaatgga ggatatcgtc aaggtttgac
     7681 tgatgaaaaa tcacacctgc aatatagtaa agacaacgcc aaacttcaat tgagaaatat
     7741 ccttaacggc taccaaagtg acctagggcg aaactactct agctattatt actacaatct
     7801 aagaaccgtt atgggactat caagtgagca agagattgaa aaatattatg aagagcttaa
     7861 gaacaagtta catgatatgt acaatcatta ttaagtcaaa ggtttaaaaa tggcgactag
     7921 cccctcaaaa aaagaggcca cactcattta aatttaaatg agtgtggcct ctttttgagg
     7981 agacgcaagg ggttaaaggg ctgtgacata gagttgctta gcaatatttt cagggatgac
     8041 aagttccttg tcgccataac aaatcgtata ggtttttgca aaggtatcaa tttgagttaa
     8101 ggttagctcg gtattgatac tcaggtgatg tgtttctaga tactgaatta aatcaaagtg
     8161 gtcgtggatt ctgcttaggc gaaaccgtcc caactccgtg atggtgttga gagttgtagt
     8221 gttcatttcg acaagaggct gaccatagcg aggaatagtc cctccgtgtg ggcagaaatc
     8281 tggaaaatca aggatcttgt ctaaacggtc gataaaggtg tctgagacag tgtgctctaa
     8341 gacttcagct tcttggtgca cttcttgggt attatagccc agctgatgaa tcaaaaatac
     8401 ctcaatcaag cggtgtttgc ggtagaggtt agcaacaaga gcatagcctt tgtcttttag
     8461 caaatagcct tttgctttat ctttgacaat ccagccttgt gaaatcattt ttttaatcat
     8521 ctctgaaacg gcaggtgccg aaacgtgcat cttttctgca accattttat ttgtaatctt
     8581 gggttcttgt tctccaattt catagataca tttcaagtaa tcttctttat taggcgtcat
     8641 atcgtttggc ctttctctta tttataatga ttattatatc agaattttta ggaaaaagct
     8701 tgacaaaaag cctaaaagag gatatcctta tagcataatt aactaaactt aattaaataa
     8761 ataatatatc ctaaggagag aaatgatggg aaagagaatg agcctcattt tgggtgcttt
     8821 tttatctgtt tttcttttag tagcttgttc ttcaactggt actaaaactg ctaagagtga
     8881 taaattaaaa gtcgtggcaa ccaattcaat tattgccgac atgacaaaag ctattgctgg
     8941 tgataaaatc gatctgcaca gcattgtgcc aatcggtcaa gatcctcatg agtacgaacc
     9001 attaccagaa gatgttgaaa aaacaagtaa tgctgatgtg attttctata atggtatcaa
     9061 tctagaagat ggtgggcaag cttggttcac caaactagtg aaaaatgctc aaaaaacgaa
     9121 aaacaaagat tactttgccg tgtctgatgg cattgatgtg atttacttgg aaggtgcaag
     9181 cgaaaaagga aaagaagatc cacatgcttg gttaaatctc gaaaacggaa tcatttattc
     9241 aaaaaacatt gccaaacaat tgattgcaaa ggatcctaaa aacaaagaaa cttatgaaaa
     9301 gaacctaaaa gcttatgtgg ctaaattgga aaaactagac aaagaagcca aatcaaaatt
     9361 tgatgctatt gcagaaaata aaaaattgat tgtgactagt gaaggttgct tcaagtactt
     9421 ttcaaaagct tacggtgtcc catctgctta tatctgggaa attaacaccg aagaagaagg
     9481 aacaccagat caaatttcat cattgattga aaaactaaaa gtcatcaagc catctgcgct
     9541 ttttgtagag tcaagtgtcg atagacgccc tatggaaact gtttctaaag atagtggtat
     9601 tcctatttat tctgagatct ttacagattc aattgctaaa aaaggtaaac ctggcgatag
     9661 ttattatgct atgatgaaat ggaaccttga caaaatttct gaaggtctag caaaataaga
     9721 taacaataaa gcacagcgat tttagtgttg tgctttgttt tatttatgta aaggagacaa
     9781 aatgattaca actaacaatc tttgtgtgac ctacgatggc aacagtaatg ctttagaagc
     9841 gattaatgtg acaattgaag gtccttctat cgttggtatt atcggtccta atggagctgg
     9901 gaaatcaacc tttatgaaag ctattttaaa tcttattgat tatcaaggtc acgtaacggt
     9961 tgatggcaaa gatggtcgta agcttgggca tacagtagct tacgtagaac aacgaagcat
    10021 gattgactat aattttccta ttactgttaa agaatgtgtg gcgctaggga cttatagtaa
    10081 attaggcctt tttcgccgag taggaaaaaa acaatttgag caggttgata aggttctcaa
    10141 acaagttggt ttagaagact ttggccatcg accgataaaa tccttatctg gtggtcagtt
    10201 tcagcggatg ttggttgcgc gttgcttgat tcaagaatca gactatattt tcttagatga
    10261 accgtttgtt ggcattgatt cggtcagcga aaaaatcatt gtagatcttt tgaaagagct
    10321 caaaatggct ggcaaaacga ttttaattgt acatcatgat ttgagcaaag tagagcatta
    10381 ttttgacaaa ctcatgattt taaataaaca tttggtggct tatggcaacg tttgtgaggt
    10441 atttactgtt gataccttgt caaaagctta tggcaatcat ttgattttag gaaaggagat
    10501 ggtgtaaatg tctatgaaat tttttgaggg cttgatgtca taccactttt tacaaaatgc
    10561 actgataacg gctgtagtca ttggtatcgt ctcaggtgct gtagggtgtt ttattatcct
    10621 taggtcaatg tctcttatgg gtgatgccat ctcacacgct gttttaccag gggttgcttt
    10681 gtcatttatt ttaggagtca atttttttat tggagcgatt atttttgggt tattagcttc
    10741 tgttattatt acttatatca aggaaaactc tgtcattaaa ggagatacgg ctattggtat
    10801 cacctttagc tcttttttgg cactgggagt catcttgata ggggtagcca atagttcgac
    10861 ggacttattt catattttgt ttgggaatat tttagctgtg caagacagcg ataagtggat
    10921 tactattggt gtttcgattt ttgttttagg ggttattagt ctctttttca aagaactatt
    10981 attaacatca tttgatccta tcttagccaa atcaatgggt gtgaaggtca atgcgtatca
    11041 ttatttgttg atggtcctat taactttagt ggctgttacg gcgatgcaaa gcgtgggtac
    11101 tatcttgatt gttgccttac tgattacgcc agcagcgaca gcttatttat atgctaatag
    11161 cttaaaagta atgttagtga tgtcatcttt actaggcgct ttagcatcgg ttttaggact
    11221 ttatctgggc tataccttta atgttgccgc agggtcaagt atcgtactga cttctgcgat
    11281 gatgtttttg atcagtttct ttgtttcacc caagcaaggc tacctcaaaa gatggatgca
    11341 aaaaaaggaa aaaacacctt aaacttttca ctttaaacac cttagtggtt tgcaaatagt
    11401 ggcaaatgac atcaaagggt gttttttata tgtcatcaaa agaccataaa aaaccttatc
    11461 aaaccaaggt atttagccta ttatctgata aggttttttt aagcatgact tagtttttaa
    11521 agcgataatc tttgacaatg tcaattgagg taatcgtaat gtcttgtttt ggtttatcat
    11581 tttggttgat agaagtcgcg gcaattttat cgacaacatc cataccatca atgacttgac
    11641 caaatacagt ataaccgcca tctaagcttg gattgccgcc atgctcatag gcagagatga
    11701 taggttttgg gtagttggta cttgataatc ccttgctttg atttttcttg ttttggttga
    11761 tataaaattg gctaccgtta gtattagcgc cagcatttgc catggcaaga gcaccgcgaa
    11821 tatgatataa aaatggagag atttcgttga caaagccatt gccagcatct tttttaggat
    11881 ccttgccctt ccaaatcgat tcaccacctg tgccatctcc tttggggtca cctgattgaa
    11941 tcataaagtc gttgatcaca cgatggaagg taaggttatc atagtagcct tttttagcat
    12001 gggtgaggaa gttctcaaca gctaagggag catattttgg gaataactta agggtgatgt
    12061 ccccttgact tgtcctcatt acgaccttag cttcttcttt gccgacttct ttggttagtt
    12121 gtggaaattg gctagcatca gctttgagag ctttttgaat gctttcttca taggctttag
    12181 aagctgcttc gctttcttct ttggcagttt tttcatcaat gtatttatcg ccttttatag
    12241 cgcggtcaac agattcacaa gcactcaaac taagtaaact aatggctact aaactgagag
    12301 ataataattt tttcatgtct actcctaaga atgattttct ttattttatc ataaaatgca
    12361 acagaaaata gtagtaaaga gttaaaaacg cctatttttg tgttttatga tctaaccttg
    12421 gttaaaaggc tgctacgact gttattatag cacaagatgc tatagaaaaa cttaaaacac
    12481 cttggttttt tagagctatt tcctaatagt taaaaaatgg tataatagtg ttatggttaa
    12541 aagaaatcaa agaaaaaaaa gtgcgcctaa gaagcgttta acaaaagcag aagtggaaaa
    12601 gcaacgtgcc attaagagga tgattttatc tgttttaatg gctttgttgc ttatttttgc
    12661 gatgcttcgc ttgggcgtct ttggcgtgac aacttataat atgattcgtt ttttggtggg
    12721 tagtttagcc tatccgttta tgtttgcctg gttaatttac ttattttgtt ttaaatggtt
    12781 acggcaaaaa gatggaatga ttgcgggagt tgttattgcc tttttgggat tgctagttga
    12841 gtggcacgcc ttcttatttg cgatgcctag gatgcttgat caagctattt ttctaggcac
    12901 tgctcggcta attacaagag atttactagc cctgcgcgtg actgaatttg ttggtggagg
    12961 aatgcttggt gcattacttt ataaacccat agccttttta ttttcgaata tcggctctta
    13021 ctttattggt tttttgttta tcttattagg attatttcta atgacgcctt gggatatcta
    13081 tgatgtgagt cactttgtga aagaggctgt tgataaacta gcagtggctt atcaggaaaa
    13141 taaagaaaag cggttcatca aacgagaaga gcaccgctta caagctgaaa aagaggcttt
    13201 agagaaacaa gcacaagagg aagaaaaacg tctagcagaa ttgacggttg atcctgagac
    13261 gggagagatt gttgaggata gtcagtctca agtcagctat gatttggctg aggatatgac
    13321 aaaagagcca gagattcttg cttatgatag tcacctcaaa gacgatgagg caagcttatt
    13381 tgaccaagaa gacttggctt atgctcatga ggaaattggg gcttatgact ctttatctgc
    13441 tttagcatct tctgaagatg agatggatat ggatgaacct gttgaagttg atttcacacc
    13501 aaaaacccat cttctttata aacttccaac tattgattta tttgcaccag ataagcccaa
    13561 aaaccagtcc aaagagaaaa acttagtccg caaaaatatc aaggtgcttg aagatacctt
    13621 ccaaagtttt gggattgatg tcaaggtaga acgagcagaa atcgggcctt ccgtcaccaa
    13681 atatgaaatt aaaccagctg tcggggtccg agttaatcgt atttcaaatc ttgctgatga
    13741 tttggcactt gctctggctg ctaaagatgt tcgtattgaa gcaccaattc ctggaaaatc
    13801 gttaataggt attgaagttc ctaactcaga aattgcaacg gtttcttttc gcgaactttg
    13861 ggaacaatct gatgccaatc ctgaaaacct tttagaagta ccactaggta aagctgttaa
    13921 tggcaacgct cgcagtttta acttagctag aatgccgcat cttttggtag ctggttcaac
    13981 tggttcaggt aaatctgtgg cagttaatgg cattatttca agtattttga tgaaggcacg
    14041 tccagatcaa gttaagttta tgatgattga ccccaaaatg gttgaattat ctgtttataa
    14101 tgatattcca catttattaa tccctgttgt aaccaatccg cgtaaagcca gtaaggcact
    14161 ccaaaaagtg gttgatgaga tggaaaaccg ctacgagtta tttagtaaaa ttggtgtgcg
    14221 taatatagca ggttataata caaaggttga agagtttaat gcttcttctg agcaaaaaca
    14281 aataccgttg cctttaatcg ttgtcattgt agatgaattg gctgacttga tgatggtggc
    14341 tagtaaagaa gttgaagatg ctattattcg tttgggacaa aaagcacgtg ctgcaggtat
    14401 ccatatgatt cttgcaactc aacgtccctc tgtagatgtt atttctggtt tgattaaagc
    14461 aaatgttccg tcgcgtatgg catttgctgt ttcaagtggt actgatagcc gtacaatcct
    14521 tgatgaaaat ggtgctgaaa agctcttggg acggggtgat atgctcttta agccgattga
    14581 tgaaaatcac cctgttcgct tgcaagggtc tttcatctca gatgatgatg tggagcgtat
    14641 tgtcaacttt atcaaagacc aagctgaagc ggattatgat gacgcctttg atcctggtga
    14701 agttagcgac aatgatcctg gtttttctgg aaatggcgga gctgctgaag gtgatcctct
    14761 ttttgaagaa gcaaaagcct tggtcttaga aacacaaaaa gctagtgcct caatgattca
    14821 aaggcgtttg tcggttggat ttaatcgtgc cacgcgcttg atggatgaat tggaagaagc
    14881 aggtgttatc ggtccagcag aaggaaccaa acctcgtaag gtattgcaga caaactaaaa
    14941 gaacctgacg tctcatgatg agatgttagg ttcttttttt gtgatgtcag gccagttgat
    15001 gagatgccta tgctaatgta aaaataaaga taactagaat aaggtagaaa ataacggtga
    15061 ctaaaaagcc aactcgccaa aatagcttca taaagcgatg gtaagaaaac gactgagttc
    15121 ggatgactag cagtagtgaa atgacgatgg ctagcagcga catgataata aggtaataag
    15181 gcagtaaatt atgggtgaaa aattttcctg agacaagcac aatttctatc gcaaaaagta
    15241 aaagtgcgac atctggaaat ttaaatccct ttttattaag tttaaataaa gaggttacaa
    15301 tcatggcaaa aagaggcgtt actatcaaga aagctaaggc agttaattta tagatcatca
    15361 taggtctatt ttatactcaa atcccttact tgtaaactga tacttacctg ttgtgataga
    15421 aaatgatctt tgagagggaa agcgcctact tcaatttaaa cattgcaaaa ggcatcagct
    15481 attttaacaa aaagacttga tttattttgg caataagcta taatagtaag gtatgcaata
    15541 ttgcatatct gtgggaggta aaaatctcaa ttaccgccaa aaccacaaca ggaggatttt
    15601 taaaatggct aaaaaagtcg aaaaacttgt aaaacttcaa atccctgctg gtaaagctac
    15661 accagctcca ccagttggac cagctcttgg tcaagcaggt atcaacatca tgggcttcac
    15721 taaagaattt aacgctcgta cagctgatca agctggtatg atcatcccag ttgttatctc
    15781 agtttatgaa gacaaatcat ttgatttcat cactaaaaca ccaccagctg ctgttctttt
    15841 gaaaaaagct gcaggtgttg aaaaaggatc aggtacacct aacactacta aggttgcgac
    15901 agttactcgt gcacaagtac aagaaattgc tgaaactaag atgccagatt tgaacgctgc
    15961 aaacattgaa gctgcaatgc gtatgatcga aggtactgct cgttctatgg gattcactgt
    16021 tactgactag tcagtcaaga acccctatta cccgcacgac ttcatcataa gagatgagtg
    16081 acgtgggaga ttttaaatca aatcgatatg accacattac aaggagaatt ttaaaatggc
    16141 taaaaaaagc aaacaaatgc gtgctgcact tgaaaaagta gatagcacaa aagcgtacag
    16201 tgtagaagaa gctgtagcat tagtaaaaga aacgaacttc gcaaaatttg atgcgtctgt
    16261 tgaagttgct tacaacttga acattgacgt tcgtaaagca gaccaacaaa tccgtggcgc
    16321 aatggtattg ccaaacggaa ctggtaaaac acaacgtgtt cttgtttttg cacgtggtgc
    16381 aaaagctgaa gaagcaaaag cagctggtgc agacttcgta ggtgaagacg accttgttgc
    16441 aaaaatcaat ggtggatggc ttgactttga cgttgttatc gcaacgccag acatgatggc
    16501 tatcgtaggt cgtcttggac gtgtccttgg acctcgtaac ttgatgccaa accctaaaac
    16561 tggtacagta acgatggatg ttgctaaagc cgttgaagag tctaaaggtg gtaaaatcac
    16621 ttaccgtgct gacaaagcag gtaatgttca agctcttatt ggtaaagttt catttgatgc
    16681 tgacaaattg gttgaaaact tcaaagcctt ccacgatgta atggctaaag ctaaacctgc
    16741 aacagctaaa ggaacttaca tggcaaacgt ctcaatcaca tcaacacaag gtgttggtat
    16801 caaggttgat cctaactcac tttaagaaaa aaattagggc atcgcctaat catagcaaaa
    16861 agacaaattt ctgaagacaa atcttcacta gaggtttgtc tttttttatg gtttaaaatg
    16921 gaatgcaaac aaaaaagtgt aggcgataat accatgaaag gagctgattc tcttaatgag
    16981 atgtggtatt aacacatcat gagctcacaa aaaatgataa aggaagtatc ggtggtgtta
    17041 aaaaagggat tttaattgat atttattagc ctctaaaatg tcctttccct attcataatt
    17101 gagggtttgt ggtaaaatag taaggacaaa ctaaggagaa catagtagtg gaacctaaat
    17161 atcaacgtat attaattaag ttatctggtg aagcattagc aggtgaaaaa ggagttggca
    17221 ttgacattcc aactgttcag gctattgcaa aagaaattgc cgaagttcat gtgtcgggag
    17281 tacagatcgc tcttgttatt ggtggaggca atctctggcg tggagagcct gcagcagacg
    17341 ctggaatgga ccgtgttcag gctgattaca ctggcatgct tggaacggtg atgaatgccc
    17401 tagtcatggc tgatagtctt caacattatg gtgttgatac ccgtgtgcaa acagctattc
    17461 ctatgcaaaa tgtagcagaa ccttatattc gcggacgtgc cttgcgccat ctagaaaaaa
    17521 atcggattgt tgtttttgga gctggtattg gctcgcctta tttttcaaca gacaccaccg
    17581 cggcactgcg tgctgctgag attgaagcag atgctatttt aatggcaaaa aatggtgtgg
    17641 atggggtcta taatgctgat cctaaaaaag atgctaatgc ggttaaattt gatgaattaa
    17701 cacatggtga agtgatcaaa cgtggtctca aaatcatgga tgcaacggca tcgaccttat
    17761 cgatggacaa cgatattgat ctggtggttt tcaatatgaa tgaagctggc aatattcaac
    17821 gtgttgtctt tggagaacat attggaacta ctgtatcaaa taaagtttgt gactaaaagt
    17881 tagaaaagaa agagagtaaa aaaacatggc aaatgcaatt attgaaactg caaaagaacg
    17941 ttttgcacaa tcccatcagt ctttatcacg tgaatatgcc agcattcgtg cgggtcgtgc
    18001 caacgctagt cttttagacc gtatccaagt tgattattac ggggcaccga cgccattaaa
    18061 tcaattggct tcaatcactg tgccagaagc gcgtgtctta ttgatctcgc cttttgataa
    18121 atcttctatc aaagatatcg agcgcgctct taacgcatca gatttaggca ttacacctgc
    18181 taacgatggc tctgtcattc gtttggttat tccagctttg accgaagaaa cacgtaaaga
    18241 attagccaaa gaagtgaaaa aagttggtga aaatgctaaa attgcaatcc gtaatatccg
    18301 ccgtgatgct atggatgatg ctaaaaagca agaaaaagca aaagaaatca ctgaagatga
    18361 gttaaaaaca cttgagaaag atatccaaaa agcaaccgat gatgctatca aagaaattga
    18421 ccgcatgacg gctgaaaaag aaaaagaatt gctctcagtg taacaggatt tctacgaaaa
    18481 atagacgact atagacacaa aaagataggt gaccatttca gaagcgtttg gttttgattt
    18541 gtccctattt tttaaagaaa gaaaaaagat atgaatgatt tactagcaac agtcattact
    18601 gggcttatta aagaagaaaa cgctaatgac tattttatcc aaaaagaggg gtttaccttt
    18661 accttgtcta aagcagaagg agaacgccag attggtgata tggtcacagg ctttgcctat
    18721 acagacataa agcaaaaggc acgtctcaca accaaagaga tccgttcaac acggacaagt
    18781 tatggctggg gggaagtgac agaggttcgt cgtgacctag gcgtttttgt cgatacagga
    18841 attccaaata aagaaattgt ggtttctttg gacgtgttgc ctgaaatgaa agaactatgg
    18901 cctaaaaaag gggataaact ttacattcgc ttagaagtgg ataaaaaaga ccgtatttgg
    18961 ggacttccag cagagcctga ggtctttcaa aagatggcta gccctgcata caataacatg
    19021 caaaatcaac attggccagc aattgtttac cgcctaaaac taacaggaac gtttgtttac
    19081 ctgcctgaaa acaacatgtt gggctttatt cacccaagtg aacgctacgc agaaccgcgc
    19141 ttaggtcagg ttttagatgc ccgtgtgatt ggctttagag aggtcgatcg taccctaaac
    19201 ttgtcgttga aaccacgttc ttttgagatg ttggagaatg acgctcagat gattgttact
    19261 tatctggaag ccaatggtgg tttcatgacc ttaaatgaca agtcaagtcc agaagagatt
    19321 aaggcaacct ttggtatttc aaaaggccag tttaaaaaag ccttgggtgg attgatgaaa
    19381 gctaaacgca tcaaacaaga cgccacagga actgaattaa taggataaaa atgctttgcc
    19441 actggcaaag ttttttgtta caatgaagac cattaactga agaaaaaggg gatatagaga
    19501 atggaaagag ccatttttgc aggaggttgt ttttggtgta tggtgcaacc ttttgaggag
    19561 caagcaggta ttttgtcagt cagaagtggc tacacaggtg ggcatctccc aaatcctagc
    19621 tatgaacaag tttgtgccaa aacaacagga catacagaag ctgttgaaat tatttttgac
    19681 cctaagcaaa tcgcttataa agatttggta gagctctatt gggcgcagac ggatccaaca
    19741 gacgcctttg ggcaatttga agatcgtggg gacaactacc gtcctgtcat ttactacaca
    19801 acggaaagac aaaaagaaat tgcagagcaa tcaaaagcaa acttgcaagc ttcaggacgt
    19861 tttgaccaac ccattgtcac cactattgaa ccagcagagc cattttatct cgcagaggat
    19921 tatcaccaag gtttctataa aaagaatccc aagcggtatg cacaaagcag tgctattcgt
    19981 catcagtttt tagaggagaa ttggtcatga gaaaatcatt ttacagctgg ctgatgacac
    20041 aacgtaaccc taaatcaaat gaacctgtgg cgattttagc agatttggtg tttgatgaca
    20101 ccacttttcc aaagcatacc aatgattttg aactcattag tcggtatcta gaagatcaag
    20161 ctagtttttc ctttaattta ggtcaatttg atgaaatctg ggaagattat ctagcacatt
    20221 aatacgtgga taaaaaagag tcatatcgac tcttttgaag ggttatcacg ttattattac
    20281 aaaatgacat cactttcttt caaaaaaatg acaagctact ttttttctta aaaatatgct
    20341 atgatatagc ttagaaaaaa ataaaaagga agcagagatg attattacta aaaagagctt
    20401 atttgtgaca agtgtcgctt tgtcgttagc acctttggcg acagcgcagg cacaagagtg
    20461 gacaccacga tcggttacag aaatcaagtc tgaactcgtc ctagttgata atgtttttac
    20521 ttatactgta aaatacggtg acactttaag cacaattgct gaagcaatgg ggattgatgt
    20581 gcatgtctta ggagatatta atcatattgc taatattgac ttaatttttc cagacacgat
    20641 cctaacagcc aactacaacc aacacggtca ggcaacgact ttgacggttc aagcgcctgc
    20701 ttctagtcca gctagcgtta gtcatgtacc tagcagtgag ccattacccc aagcatctgc
    20761 cacctctcaa tcgactgttc ctatggcacc atctgcgaca ccatctgatg tcccaacgac
    20821 accattcgca tctgcaaagc cagatagttc tgtgacagcg tcatatgagc tcacatcgtc
    20881 aacgaatgat gtttcgactg agttgtctag cgaatcacaa aagcagccag aagtaccaca
    20941 agaagcagtt ccaactccta aagcagctga aacgactgaa gtcgaaccta agacagacat
    21001 ctcagaagat tcaacttcag ctaataggcc tgtacctaac gagagtgctt cagaagaagt
    21061 ttcttctgcg gccccagcac aagctccagc agaaaaagaa gaaacctctc agatgttaac
    21121 tgcgccagca gcacaaaaag ctgtagctga caccacaagt gttgcaacct caaacggcct
    21181 ttcttacgct ccaaaccatg cctacaatcc aatgaatgca gggcttcaac cacaaacagc
    21241 agccttcaaa gaagaagtgg cttctgcctt tggtattacg tcatttagtg gttaccgtcc
    21301 aggtgatcca ggagatcatg gtaaaggttt ggccattgat tttatggtgc ccgaaaattc
    21361 tgctcttggt gatcaagttg ctcaatatgc cattgaccat atggcagagc gtggtatttc
    21421 atacgttatt tggaaacagc gattctatgc gccatttgca agtatttacg gaccagccta
    21481 cacatggaac cccatgccag atcgcggcag tattacagaa aaccattatg atcatgttca
    21541 tgtctccttt aatgcttaat tcatgctatc aaaaaaaact cacgtttagg cgtgagtttt
    21601 ttgacaattc tgacagagta agccctataa gaggctgaga tacgctttta atacctgttg
    21661 tttttctcac cctttagaca gttttaacgt tatgtctaaa agagatggtt tttattagcg
    21721 caaatatggg tttaggggta aaatataggt aattaacctg atatgatcat gataaaggta
    21781 gaagaatacc tattatttcg tgacaactga gcaatctgcc cttacctttg gagtgatgat
    21841 atcactttgc ttgactattc aaggaggtct tgaaatgtat tatactagtg gtaattacga
    21901 agcttttgcg acacctcgaa aacctgaagg ggtagatcag aaatcggctt atattgttgg
    21961 tactggttta gctggtttag cagcagctgt tttccttatt cgcgatgggc atatggctgg
    22021 ggaacgcatt catctgtttg aggaattgcc tttagcaggt ggttctttag atggtattga
    22081 aaagcctcat cttggttttg tgacccgtgg tggtcgtgag atggaaaatc attttgagtg
    22141 tatgtgggac atgtatcggt ctattccctc actggaaatt cctggtgcgt cttatttgga
    22201 tgaattttat tggttggata aggatgatcc taactcatcc aactgtcgtt tgattcacaa
    22261 gagaggaaat cgtgtggatg atgacggcca gtatacgctc ggtaaacagt caaaagaatt
    22321 aatccattta atcatgaaga cagaagaatc tctaggagat caaaccattg aagagttctt
    22381 ctcagaagat ttctttaaga gtaatttttg gatctattgg gcaaccatgt ttgcttttga
    22441 aaaatggcat tctgctgtag aaatgcggcg ctatgcgatg aggtttatcc accatattga
    22501 tggtttgcca gatttcacct ctctcaagtt caacaaatat aaccaatatg attctatggt
    22561 caaaccgatt attgcttacc tagaatcaca cgacgttgac atccaatttg acacaaaagt
    22621 cactgatatt caggtggaac aaacagctgg taaaaaggta gcaaaaacca tccatatgac
    22681 ggtgtctggg gaggctaagg cgattgagct aacacctgat gatttggttt ttgtgaccaa
    22741 tggttctatt actgaaagta gcacatacgg tagtcatcac gaagtggcta agccaaccaa
    22801 agcgttaggt ggttcttgga atttatggga aaatctagct gctcaatcag atgattttgg
    22861 tcatcctaaa gtgttttacc aggacttgcc tgctgaaagc tggtttgtgt ctgccacagc
    22921 aaccataaaa cacccagcta tcgagcctta tattgaacgt ttgacccacc gtgatttgca
    22981 cgatggcaaa gtgaacactg gcggcatcat cactattaca gattctaact ggatgatgag
    23041 ctttgccatt caccgtcaac ctcattttaa agaacaaaaa gataatgaaa ccactgtctg
    23101 gatttacggt ctttattcca atagtgaggg caattacgtc cacaagaaaa ttgaggagtg
    23161 tacaggtcaa gaaatcacag aagaatggtt gtaccacctt ggggtacctg ttgataaaat
    23221 caaggactta gcgagtcagg actatatcaa tacagttcct gtttacatgc cttatattac
    23281 gagttacttt atgccacgtg tcaaaggaga ccgtccgaaa gttatcccag atggttcagt
    23341 caacttggcc tttattggta actttgcgga atctccatct cgagatacgg tctttacgac
    23401 tgagtattct attcgtactg ccatggaagc agtgtatagc ttcttgaatg tggaacgagg
    23461 cattccagaa gtctttaatt cagcctatga tattcgtgaa ttgctcaaag ccttttatta
    23521 ccttaatgat aaaaaggcaa tcaaggatat ggatttgcca attcctgcac tgattgagaa
    23581 aatcggacat aaaaaaatca aggatacctt tatcgaagaa ttgctcaaag atgctaatct
    23641 tatgtaacat gctttagagt agttaaagct gataagttta ggcttatcag cttttttgat
    23701 gatttataga aaagtgataa aggaaaagtc tgacgtgaac gtcacataag aatttaaaat
    23761 ttgttataat gtaagcaata aagatgaaag aaagagggac tctatttgca agagtattct
    23821 attgacatta ccttaaccca tcctgatgat gttttagctc tttttggtag caacgagcgt
    23881 catttgaagc taatagaagc tcatttagga gttattgttc acgcaagaac cgagcgagtc
    23941 caagtgattg gtgatgatga agaagctgtg gaattggctc gattgaccat caaagcccta
    24001 ctggttctag tgggtcgtgg catggtggtc aacacatcag atgtggtgac agctttatct
    24061 atggcagaat ctcatcagat tgaccaattt atggcgcttt atgaagaaga aatcattaaa
    24121 gataactatg gtaaggcaat acgagtcaaa acattaggtc aaaaaaccta tgttgatagt
    24181 gtcaaacgtc atgatgtggt ttttggtgta ggacctgcag ggacagggaa aaccttctta
    24241 gctgttacgc ttgcagtcac tgctctgaaa agaggacagg taaagcgtat tattttgacg
    24301 cgtcctgcgg tagaagctgg tgaaagccta ggttttttac caggcgattt gaaagaaaag
    24361 gtggatcctt acctcagacc ggtttacgat gccctttatc acattttagg caaggaacaa
    24421 accacacgcc tgatggaacg agatgtgatt gagattgctc cgttagctta tatgcggggt
    24481 cgtactctgg atgacgcttt tgttatctta gatgaggctc aaaacacgac catcatgcaa
    24541 atgaagatgt ttttgacccg tcttggtttt aattctaaaa tgattgtcaa tggagatacg
    24601 agtcagattg atctccctcg aaatgtcaag tctggtttga ttgatgctac tcagaaatta
    24661 caaggcatta aacagattga ttttgtctat ttctctgcta aagatgttgt ccgacatcct
    24721 gttgtggctg atattatcaa ggcttatgaa acgtcctcag aggagatgaa ggacttacta
    24781 aaacctaagg ctagtgacgt tgaagctgac taccagccag gcttgacaaa ataccctgtg
    24841 atcggtcaag agcactaaga cctttacgat gatgtttaat atggcctttt taaggaggat
    24901 tctatggatg atttaaccaa agctattatg gcagatgagg ctaatctctc ctataccgaa
    24961 agaggtattt ttcctttata tgatgctcct caaacagcta ggattattat tgttggccaa
    25021 gctcctggaa tagtagctca agaaaccaaa ctttactgga atgatcgtag tggcatccgc
    25081 ttacgagact ggctaggtgt ggacaatgac accttttacc actcaggatt gtttggcatt
    25141 atccctatgg atttctatta tcctggtaag ggaaaatccg gtgacttacc acctagagaa
    25201 ggttttgcgg ctaagtggca cccgccatta agagcattga tgccagaagt tgaattgacg
    25261 attttggttg gtcgctatgc tcaggacttt taccttggta acaaggctta caaaacctta
    25321 actgaaacag tccgtcactt tgaggattac ttgccagact attttccact tgttcatcct
    25381 tctccaagaa accaattgtg gttagctaag aacccctggt ttgagcagga tttattacct
    25441 atcttgcaaa aacgtgtgga ggcaattcta accaaatagg ccctgattta cctagcattc
    25501 ccatttttaa ggggcttgtg gtataatggg taaataacaa atgctgattg aaaggataag
    25561 ggaaattatc tgtcagataa taatgggtgc ccaacatacc aaatgaggtg ggcagccctt
    25621 ccctaacaat taaccttatg tatatcgaga tgattgacga aacgggacaa gtttcgcaag
    25681 agattatgga gcaaacactt gatttgctca attttgctgc tcaaaagacg ggcaaagaag
    25741 aaaaagaaat gtctgtgacc tttgtgacca atgaaagaag tcatgaactc aacttagaat
    25801 accgagatac tgatcgtcca acagatgtga tttctctaga atataagcca gaaacgccta
    25861 ttttatttag tcaagaggat ttggctgctg atcctagttt ggcagagatg atggcagagt
    25921 ttgatgctta tattggcgaa ttgtttattt ctattgacaa ggcgcgtgag cagtcccaag
    25981 aatatgggca ctcttttgag cgtgaaatgg gatttttagc tgttcatgga ttcttacata
    26041 ttaatgggta tgatcactac acccttgaag aagaaaaaga gatgtttacc ttacaggaag
    26101 agattttgac tgcttatggc cttacacgac aataatacca ccaaacggaa atggaaaaac
    26161 agaaccatta cctcaagctt ggagtttgcc ttgacagggg ttttcacagc ttttaaggaa
    26221 gaacgcaatc tcagaagtca ccttttgtct gcctgtttag cttgtgttgc tggtttattt
    26281 tttagcattt cagccatcga atggttattt ttacttctag ccattttttt ggtcattacc
    26341 ttagaaattg tcaattctgc tattgaaaat gtagttgatt tggctagtga ctatcacttt
    26401 tctatgctag ctaaaaatgc taaggatatg gcagcaggtg ctgttttgat gatttctggc
    26461 tatgctgtct tgacaggact tattattttt attcctaaaa tttggaatat tttcgttcat
    26521 taaaaagaaa ggaatgggct atcctatgtg atgatggcat aggagaataa ggaaaggaca
    26581 agacggttaa gcttagtgac aagcttgatc tgaagcccta ccgttaaagc ccgtaattat
    26641 ctatgtttaa atcaggcttt gtagccattc ttggtcgtcc aaatgttggc aaatccacct
    26701 ttttaaatca cgtcatgggg caaaaaattg ccatcatgag tgacaaggct cagaccaccc
    26761 gtaataaaat tatgggcatt tacaccacag aaacagaaca aattgtcttt attgatacgc
    26821 caggtattca taaaccaaag accgcccttg gtgattttat ggttgaatct gcttatagta
    26881 ctttacgtga agttgagacg gttcttttca tggttcctgc cgatgaaaag cgtggtaagg
    26941 gtgacgacat gattatcgag cggctaaaag cagctaagat tcccgttatt ttagtcatca
    27001 acaaaattga taaggttcat ccagaccaac ttttggaaca gattgatgac ttccgtagcc
    27061 aaatggattt taaagaagtg gtcccaattt ctgccctaga aggtaataat gtgccaaccc
    27121 taatcaagtt attaactgat aatcttgaag aaggtttcca atattttcca gaagatcaga
    27181 ttactgatca tccagaacgt ttccttgtgt cagaaatggt tcgtgagaag gtactgcatt
    27241 tgacgcaaca agaggttcca cattccgtag ctgttgttgt cgaatccatg aagcgagatg
    27301 aagagactga taaagtgcat atccgtgcaa ccattatggt ggagcgcgat agccaaaaag
    27361 gcatcatcat tggaaaacaa ggagccatgc tcaaaaaaat cggaaaaatg gcgcgccgtg
    27421 atattgaact catgttaggt gacaaggtct acttagaaac gtgggtcaaa gtcaagaaaa
    27481 actggcggga taaaaagctt gatttagctg attttggcta taatgagaaa gaatactaac
    27541 atagtaaagc gagatcatat gccacaagac tacatttctt atatccgctc caaagttggg
    27601 catgataaga ttattcttaa ctttgctggt gggattttga ccaatgatga cggcaaggtg
    27661 ctgatgcagt tgcgtggtga taagaaaacc tgggctattc ctggtggcac tatggaactg
    27721 ggtgagagct ctttagagac ttgcaaacgt gagttcttag aggaaaccgg aattgaggtt
    27781 gaagctgttc gcttactgaa tgtttacact cattttgagg aagtttatcc caacggtgat
    27841 gctgttcaga ctattgtctt tatctatgaa ctaacggctg tttctgatat ggctattgat
    27901 aactttcata atgaggaaac gctcaagtta cagtttttct ctcatgagga gatagcagag
    27961 ttagagagtg tctcagccaa acatcgcctg atgttagagg aatattttag tgatagcttt
    28021 gctatggggc attaagaact ctctaggaca gttggagtat ttttggagat tggcttgtta
    28081 aaaaaatttt tgaaagacga tgtttcgaga gcttatgctc tctttttttg cttccaattt
    28141 ttctgattaa gtctgaataa ttttgttaaa tgttaacagg attttctttc caattgatac
    28201 tagcagacat caaacatttg ttttagagtt atgacgaatt gccacctagc catgcatgac
    28261 ttaggcaagt tgaacctaac tgtggcaata gacttggaag gggtgacaag aatcatttcc
    28321 taaaagaatt gatgaagtgc ctatccatta ttcgaattgt aaagttcgtc taagtaaagt
    28381 tgaatttggt ctcgaatgga ccttaatgat ttatgacttg ttgtgtcaat aacaccaaaa
    28441 actcgataat gatttttaaa tatttcctcg taattaatat gatttccgat tagaataata
    28501 tgagcatgag gataacacat acgtatttcg tttagaaggt catatacttg cttagattta
    28561 aacaagtatg atttatgata aaataaacct gacatttgta tttataatct aagtttttcc
    28621 cactaataat ttgagttttt agaaagtatc tcttgaggta atagttaata tagatagata
    28681 tcatatatcc taaaa
//
LOCUS       DAUCXI010000021        27902 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.021, whole genome shotgun sequence.
ACCESSION   DAUCXI010000021 DAUCXI010000000
VERSION     DAUCXI010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27902
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.021"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..143
                     /gene="whiA"
                     /locus_tag="VGY43_001005"
     CDS             <1..143
                     /gene="whiA"
                     /locus_tag="VGY43_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEQ4302201.1"
                     /translation="LQQVAQLRVKHPDYSIQQVADALEFPITKSGVNHRLRKINKIAD
                     DL"
     gene            276..1673
                     /locus_tag="VGY43_001006"
     CDS             276..1673
                     /locus_tag="VGY43_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEQ4302202.1"
                     /translation="MACTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMIVVKPEDQ
                     PRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATETITTNSR
                     VLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVAFSDEHDI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGIDHFEFNNPEDYLCSADLKDFIDTYHLDL
                     TYSYEHFNPRYAFGSQRDKDRHYNTPRAWIMQKFLNPEIVQDPCSFALAWCQKPYRKI
                     TVEDVKYVLSSHYQDTVYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRPNKPQEIA
                     AIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVSTDNFYWTNRLIAALADPHYNH
                     HETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQTLLNKIL
                     FDASNLMTNRFSLSD"
     gene            1825..3372
                     /locus_tag="VGY43_001007"
     CDS             1825..3372
                     /locus_tag="VGY43_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEQ4302203.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGVIGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHERNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            3519..4241
                     /locus_tag="VGY43_001008"
     CDS             3519..4241
                     /locus_tag="VGY43_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ4302204.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRI
                     TIRLALKELELRDLIYKKQGKGTYVSGIKEPVTDLSSTYSFTEQMKKMGKMPKTEILS
                     FEQYQVTPYLSGLLELDPDTEVFELERLRIADDMPLMFERSYIPAQPFQGLSIADLKR
                     KALYDIFAKDYQETIRLAEEEFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILI
                     EFTFSIARADQFRYRVQHHPNG"
     gene            4261..5460
                     /locus_tag="VGY43_001009"
     CDS             4261..5460
                     /locus_tag="VGY43_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEQ4302205.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDS
                     FLKRVCKSANGNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQCYLFESVASTDLVAAP
                     DYYLAEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEVYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKTLALLQGGDINFSEDQFRL
                     DTRHLLPEAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(5557..5817)
                     /locus_tag="VGY43_001010"
     CDS             complement(5557..5817)
                     /locus_tag="VGY43_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEQ4302206.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(5932..6873)
                     /locus_tag="VGY43_001011"
     CDS             complement(5932..6873)
                     /locus_tag="VGY43_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEQ4302207.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLAWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LVSQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
     gene            7267..7716
                     /locus_tag="VGY43_001012"
     CDS             7267..7716
                     /locus_tag="VGY43_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEQ4302208.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSEQFALTGAIKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            7892..8176
                     /locus_tag="VGY43_001013"
     CDS             7892..8176
                     /locus_tag="VGY43_001013"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEQ4302209.1"
                     /translation="MRLEEIRQEINSIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QARENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRQYQTQRLTGGDTND"
     gene            8169..9431
                     /locus_tag="VGY43_001014"
     CDS             8169..9431
                     /locus_tag="VGY43_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEQ4302210.1"
                     /translation="MIKSIATLPKPSLKEALGLIGLALPIGVAVGVVDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGTLRYCALLPSLVAACVASWTSHSLGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFACLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHV
                     GRYSGLGTHLLAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYTTVFGSATNTFWAPIFIGIEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            9546..9893
                     /gene="rplS"
                     /locus_tag="VGY43_001015"
     CDS             9546..9893
                     /gene="rplS"
                     /locus_tag="VGY43_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEQ4302211.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            10140..10211
                     /locus_tag="VGY43_001016"
     tRNA            10140..10211
                     /locus_tag="VGY43_001016"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10173..10175,aa:Arg,seq:cct)
     gene            complement(10174..10488)
                     /locus_tag="VGY43_001017"
                     /pseudo
     CDS             complement(10174..10488)
                     /locus_tag="VGY43_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234471.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            10896..11465
                     /locus_tag="VGY43_001018"
     CDS             10896..11465
                     /locus_tag="VGY43_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HEQ4302212.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVATFAPNEPEFLHVYRLREADKLAQPIWCLGAKEILEKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDINSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            11466..13418
                     /gene="gyrB"
                     /locus_tag="VGY43_001019"
     CDS             11466..13418
                     /gene="gyrB"
                     /locus_tag="VGY43_001019"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEQ4302213.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQKFKRGAVV
                     ADLEIIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRDFIEENAVYSTLDI"
     gene            13786..15510
                     /gene="ezrA"
                     /locus_tag="VGY43_001020"
     CDS             13786..15510
                     /gene="ezrA"
                     /locus_tag="VGY43_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEQ4302214.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLLEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(15642..16100)
                     /locus_tag="VGY43_001021"
     CDS             complement(15642..16100)
                     /locus_tag="VGY43_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEQ4302215.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISSKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKKTPEKTKSFWKRFLKK"
     gene            16327..17634
                     /gene="eno"
                     /locus_tag="VGY43_001022"
     CDS             16327..17634
                     /gene="eno"
                     /locus_tag="VGY43_001022"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEQ4302216.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAVLGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERGVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWDGWKALTERLGGRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(18116..19145)
                     /locus_tag="VGY43_001023"
                     /pseudo
     CDS             complement(18116..19145)
                     /locus_tag="VGY43_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677767.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19412..20953)
                     /locus_tag="VGY43_001024"
     CDS             complement(19412..20953)
                     /locus_tag="VGY43_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ4302217.1"
                     /translation="MLHLHLETKLQDKLSLLNILLDVSEVSIDQLCQETELKKQRVYN
                     LLFEMIKDLEDTLTLTICDDTVSIPYKTYQLKMPYFKKLYQTSIFLKILCFLIEPGEL
                     SLHDFIKREYISQATAYRIRTNCRKYLKKVGLNVRQNHVVGPKYRIRFLIALLHYQFG
                     MTIYDFDKTSMNKVVSLIINSNQAITLNDASKAPYEFSYFAILISLIWKRRHDNLGIP
                     QTDAFKHLKKLSIYHDIKMTSQEIIGKWYHPDLTDEDLDYIFLCFCTTNNPFHKDKWT
                     PKKVKELFELVMTKTIGKTLKASLRPLLGNNILKSLPFKRILVSFSRLFISNLQVLLP
                     DIHLFHYLRRQQKRNKSFYNTLKTIVEEWMSAEGIVGKLPSYHLLLFTIQLEELLKTY
                     LPPIPVYLLTNNTAALDLMTNALSIYFPPAIATVMPVNVEIIPFKDIVKEKQSVIIAD
                     RQYLNLIQHLYQNQGHLFLYFLFSFRDVSEAYIHKAFLDFRQKRYDEFIVTLLDTYHK
                     NLSSP"
     gene            21425..27322
                     /locus_tag="VGY43_001025"
     CDS             21425..27322
                     /locus_tag="VGY43_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEQ4302218.1"
                     /translation="MFLKHQDVKQKNWRMRKVKKLFVSSCMLLTVGLGVAVPTGFSQS
                     NGVMVVKADVTQEGSPENVLKIANSLKATTDGTKIGRYSAINTQNLDVSEYKFYYVNS
                     TKLNKNPQQRLWHYEKPKEIYDSTIRVAGDGTANIRFYADGDGSKTPNGFSFAYKFNT
                     TNLKTDHKYKLSFKQTQNNDEEVYTKYLVGKASEGVANYLTSEETSVARNVELFEGNQ
                     KTTAERKFAKHQSGEKSLQFISKTDGTASLVLAAGVKNTPKKNTDITFDSFEFIDITE
                     PAQVSSGEAIAGNKNLTVNLSGSDGRKNFSGEIIEVYKNGQLLKKETVTTAGNKVNIA
                     LSDDVVLKKDDEITFKVKQGSSGKKNQAAGKIIVQQNPAVVAEQENSKKSLEEVYNKA
                     KKAISDDEWLSDEEKRVQTAAVEKTYNEGQTSINNAETVTEIKDAFKKYSTQGNKISI
                     PDQYKKGEKAIKQEQARKSLKQVHEDTLGKIRSDDWLTEEEKATQTENAKQSYNQGEN
                     KINQSDSLKTLNQILKDYTSEEPNKKESIPNKYEKGKKEELKRDAETKLREAQETTKQ
                     AIENDPWLSPEQKKAQKENAKTRLDAGLKAVETTESLDKLKEVESDFLDKEKAESIPS
                     QHQAGTPEVARKTFLDNFEKEAKKEIESIKNDATLTDAEKATAKAKVEAQLQEAKDKA
                     KESKSFDDLKNIQDKFNSELPHTTGKPLKDQQSDAIAELEKKQQEIEKAISEDKTLSK
                     DEKEKQIADSKAKLVAEKEKVSKAPDADAVKKALELGKQEIAKAYVPQNLEDHKKKLL
                     AELKQKANDTEKAIDFDKTLTAKEKEEQKAKTKEELQKATEAVGAIDNREELDKKVPE
                     LKKAIQDSHVKGDLEGVKNKAIEDLQKVHDETVAKINGDDTLDKATKEAQVKEADKAL
                     AAGKDAITKADDADKVGAAVTEHTPKIKAAHKTGDLKKVQEEANQALDKAAEKERGEI
                     NNDITLTAKDKEQQLKEVETALTKAKAKVAEAKTADAINDARDKGVATIDAVHKAGQD
                     LGARKSGQVAKLEEAAKATKDKISADPTLTSKEKEEQSKAVNAELKKAIEAVNAADTA
                     DKVDDALGKGVTDIKNQHKTGDPVVARREAHGKQLDRVAQETKDAIEKDPTLTTEEKA
                     KQVKDVDAAKERGMAKLTEAKNADELDKAYGEGVTDIKNQHKSGDPIEARRGLHNKSI
                     DEVAQATKDAITADTTLTEAEKETQRGNVDKEATKAKEELAKAKDADALDKAYGDGVT
                     SIKNQHKSGKGLDVRKDEHKKALEAVAKRVTAEIEADPTLTPEVREQQKAEVQKELEL
                     ATDKIAEAKDADEADKAYGDGVTAIENAHVIGKGIEARKDLAKKDLAEAAAKTKALII
                     EDKTLTDDQRKEQLLGVDTEYAKGIENIDAAKDAAGVDKAYSDGVRDILAQYKEGQNL
                     NDRRNAAKEFLLKEADKVTKLINDDPTLTHDQKVDQINKVEQAKLDAIKSVDDAQTAD
                     AINDALGKGIENINNQYQHGDGVDVRKATAKGDLEKEAAKVKALITNDPTLTQADKDK
                     QTAAVDAAKNTAIAAVDKATTADGVNQELGKGITAINKAYRPGEAVKAHKEAAKVKAL
                     IAKDPTLTQADKDKQTAAVDAAKNTAIAAVDKATTAEGINQELGKGITAINKAYRPGE
                     GVKARKEAAKADLEKEAAKVKALITNDPTLTKADKAKQTEAVAKALKAAIAAVDKATT
                     AEGINQELGKGITAINKAYRPGEGVKARKEAAKANLEKVAKETKALISGDRYLSETEK
                     AVQKQAVEQALAKALGQVEAAKTVEAVKLAENLGTVAIRSAYVAGLAKDTDQATAALN
                     EAKQAAIEALKQAAAETLAKITTDAKLTEAQKAEQSENVSLALKTAIATVRSAQSIAS
                     VKEAKAKGIAAIRAAYVPNKAVAKSSSANHLPKSGDANSIVLVGLGVVSLLLGMVLYS
                     KKKESKD"
     gene            complement(27508..27624)
                     /locus_tag="VGY43_001026"
                     /pseudo
     CDS             complement(27508..27624)
                     /locus_tag="VGY43_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611995.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         9104 a         4865 c         5845 g         8088 t
ORIGIN      
        1 aattgcaaca ggtagcccag cttcgggtta agcatccaga ctattccatt caacaagttg
       61 ctgatgccct tgagttccca atcaccaaga gcggggtcaa ccatcgcttg cgtaaaatca
      121 ataaaattgc agatgactta tagaacattt ttatcgtatg agcctttgtt catacgattt
      181 ttctgtctaa aagtcgtttt ccattgtttt tttgaagtgt ctgatgttct gtgatatgat
      241 aaaagggata ataacgtttg taaaggagac tgataatggc atgtacaact atactcgtcg
      301 gtaaaaaggc atcttatgat ggctcaacca tggttgctcg aacagaagat tctcaaaatg
      361 gagatttcac gcctaaaaaa atgattgtgg tgaaaccaga agatcaaccg agacattacc
      421 gttcggtgca atcttccttt gagatggact taccggacaa tcccatgact tacacgtctg
      481 ttcccgatgc gcttggtaaa gatggtatct gggcagaagc aggcgtgaac gaggctaatg
      541 tggccatgtc agcaactgaa accatcacta ccaattctcg tgttttaggg gcagatcctc
      601 tagtagcttc tggtattggt gaggaggaca tggtgacctt agtgctccct tatatccgtt
      661 ctgcgcgtga aggggttttg cgccttggtg ccattttaga agactatggc acttacgagt
      721 caaatggtgt ggctttttca gatgaacatg acatttggtg gctggaaacg attggtggtc
      781 atcactggat tgcaagacgg gtgccagatg atgcttatgt caccaatccc aatcaatttg
      841 gcattgatca ttttgaattt aacaatcctg aagattacct ttgctcagct gatttaaagg
      901 actttattga cacgtatcac ttagatttaa cctatagcta tgagcatttt aatccgcgct
      961 atgcctttgg tagtcaacgt gacaaagacc gtcactataa tacgccacgt gcttggatca
     1021 tgcaaaaatt cttaaaccca gaaattgtgc aagacccgtg cagctttgcc cttgcttggt
     1081 gtcaaaaacc ttaccgtaaa ataacagtag aagatgtcaa atatgtattg agtagtcact
     1141 atcaggacac ggtttatgac ccttacggtt cagaaggaac tcctgttagt aagaaagtct
     1201 ttcgccctat tggcattaac cgtaccagcc aaaccgctat cttacacatt cgtcctaata
     1261 aacctcaaga aattgcggct atccagtgga tggcttatgg gtcaatgcca tttaatacca
     1321 tggtgccttt tttcacacag gtgaagacta ttccagatta ttttgccaat acttacgaaa
     1381 atgtgtctac cgacaatttc tattggacca accgtctgat tgcggctcta gcagatcctc
     1441 actacaatca tcatgaaact gatttggaca attacttgga agaaaccatg gcaaaaggtc
     1501 atgccatgtt acatgctgtg gaagcacagt tattggctgg tgaaaccgtc gatttggaag
     1561 aggaaaatca aaaaatgagt gactatgtgc aaggagaaac gcagacgctg ttgaacaaga
     1621 ttctctttga cgctagcaat ctaatgacta atcgtttcag tttgagcgat taaaagtgaa
     1681 gctaaggctg agcaactgct tagccttttt tacgataact ttttaggaaa agtaatcgca
     1741 aaaagacaaa aacttggaaa aaaaatcaaa gtatgctata cttaactggt caatttttaa
     1801 ccagttaata acaaaggagg aatcatgaaa aagaaaattc ttttaatgat gagtttaatc
     1861 agtgtctttt ttgcttggca acttactcag gcaaaacaag tcttagcaga gggtaaagtg
     1921 aaggtggtga caactttcta tcctgtttat gaatttacaa aaggggttat tggtaatgat
     1981 ggcgatgttt ccatgcttat gaaagcagga acggaacctc atgattttga gccttctaca
     2041 aaagacatta aaaaaatcca agatgcagat gcatttgttt atatggatga caatatggaa
     2101 acttgggttt ctgatgtgaa aaaatcattg acatctaaaa aagtgaccat cgtcaaggga
     2161 actggtaaca tgctcttggt agcaggagct ggacatgacc atcaccatga ggatgctgac
     2221 aaaaagcatg agcgtaataa acatagcgaa gaaggacaca accatgcttt tgacccacac
     2281 gtgtggttgt caccataccg tagcattaca gtcgttgaaa atattcgcga cagtctttca
     2341 aaagcttacc cagaaaaagc agagaacttc aaagccaatg ccgctactta tattgaaaaa
     2401 ttaaaagagc ttgacaaaga ctatacggca gcactttcag atgctaagca aaagagcttt
     2461 gtgacacaac acgcagcttt tggttatatg gcacttgact atggcttgaa ccaaatttct
     2521 attaatggtg tcacaccaga tgcagaacca tcagcaaaac gtattgctac tttgtcaaaa
     2581 tacgttaaaa aatatggcat caaatacatt tattttgagg aaaatgcgtc aagtaaagtc
     2641 gcaaaaaccc tagctaaaga agcaggagtt aaagcggctg tgcttagtcc gcttgaaggt
     2701 ttgactgaaa aagagatgaa agctggccaa gattacttta cggtcatgcg taaaaacctt
     2761 gaaaccttac gcttaaccac tgatgtggct ggtaaagaaa ttcttccaga aaaagacacg
     2821 actaagacag tttacaatgg ttatttcaaa gacaaagaag tcaaagatcg tcaattatct
     2881 gactggtcag gtagctggca atctgtttac ccctatctac aagatggtac tttagaccaa
     2941 gtttgggact acaaggctaa aaaatctaaa ggtaaaatga cagcagccga gtacaaagat
     3001 tactacacta ctggttataa aactgacgtg gaacaaatca aaatcaatgg taagaaaaag
     3061 accatgacct ttgttcgtaa tggtgaaaag aaaaccttca cttacacata cgccggcaaa
     3121 gaaatcttga cctatccaaa aggaaatcgt ggagttcgtt tcatgtttga agctaaagaa
     3181 ccaaatgctg gcgaattcaa atacgttcaa tttagtgacc atgccattgc tcctgaaaaa
     3241 gcagagcatt tccacctgta ctggggtggt gacagccaag aaaaattaca taaagagtta
     3301 gaacattggc caacttacta tggttcagac ttatctggtc gtgaaattgc ccaagaaatc
     3361 aatgctcatt aatcttaact cactaagcaa atcttctttt aaggaggttt gctttttctt
     3421 tgtggagtaa aaaaattaat aattctcaac attaatttga cgggcactta tgattataat
     3481 atactttaag tggttataac aagttagagg tgaataagat gccaaaagaa caaccactct
     3541 atttacagat tgttgatgac ttggaagtga aaatcaaaaa aagcatgaca gaaaacgata
     3601 agttgttgtc agaacgagaa ttaagtgacc tttacggtgt tagtcgtatc acgattagac
     3661 tggctcttaa ggaattggaa ttacgagact taatttataa aaagcagggc aaggggactt
     3721 atgtttcagg aatcaaagaa cctgtcactg atttatcaag tacatatagc tttacagagc
     3781 agatgaaaaa aatgggaaaa atgcctaaaa cagaaattct ttcctttgaa cagtatcagg
     3841 taacacctta cttgtctggt ctcttagagc ttgatcccga tacagaagtt tttgaattag
     3901 aacgcctaag gattgcagat gatatgccct tgatgtttga acgatcctat attcctgctc
     3961 agccttttca ggggttaagc attgcggact tgaagcgtaa agctttgtac gatatctttg
     4021 caaaggacta tcaagagaca atccgtcttg cagaagagga gttttatgcc agcattgcct
     4081 tggactatga agcggacctt ttgggaatca aaaaaggaga tcctgtctta catattattc
     4141 gtaaaactta taacgataaa aatattttga tcgaatttac tttcagtatt gcaagagcag
     4201 accagtttag gtatagggta caacatcacc ccaatggtta aagaaatggg aggttaatac
     4261 atgtttacaa aaacgcagga agctttggag gctcttggtg cagctatcac taccaaggaa
     4321 attaaacaag aaccccgttt atggcaagaa accatgacgt tttttgaaga aacaagagat
     4381 tctctggatt cttttttaaa gagagtttgt aaaagcgcta atggaaataa cgttcatgtc
     4441 atctttacag gtgcgggtac atctgagtac atcggtaata ccatttgccc ttacttgaag
     4501 aaggtgggga atcggcagtg ctatctcttt gagagtgttg cttcaaccga tttggttgcg
     4561 gcgccagatt attatcttgc tgaggaagag acggtactat tagtctcctt tgctaggagt
     4621 ggtaatagtc cagaaagtgt agcggctgtt aacctggtca atcaactagt gccaaatagt
     4681 tatcatttaa ccattacgtg tgccaaagat ggagaactgg cgaaaaaagc acagcaagat
     4741 gagcgttctt acctttattt gatgcctgaa gacgctaatg atgctggttt tgccatgact
     4801 ggtagtttta cctgtatgat gctagcggct cttttgattt ttgatgatgc taacagtata
     4861 gctcagaaag aagtttatgt gactgatatg attcttgctg ggcaagctgt tattgaccaa
     4921 gaaagacggc tacaagagct agctgattta ggatttgaac gtttagttta tctaggttct
     4981 gctggtttag ccaagttaac ccaagaagct caattaaaaa tgttagaatt gacagctgga
     5041 caagttgcga ccctctacga gtcctctatg ggctttaggc atggtccgaa atcttttatt
     5101 aatgaccgta ccttagtcat tggatttgtc aataatgatg cttacgtcag acaatacgat
     5161 ttggacatgt tagaggaaat ccaagcagat ggcattgccc ttaaaacctt ggctctattg
     5221 caaggagggg atatcaactt ttcagaggac caatttcgac tagacacccg tcacttattg
     5281 ccagaagctt acttagcttt tcccatgatt ttagtcgcgc agaccttggc cctcttaacg
     5341 gccgttacat taggaaattc ccctgacacc ccatctgcga caggaacggt taatcgtgtg
     5401 gtcaaaggag taacgattca cccttacccg actagtagtc gtcaatgcaa caaagcttaa
     5461 agcttttgtg tagaagccgt aaaacgaaat gattttgtgc tagtaggcca aaagaaaaac
     5521 cctcctgata caggaaggtt ttttgtattg tcttgcttat tttgctgcgt ttgcgtcttt
     5581 gagaccgtat tttttgttga agcggtccac acgtccatct gcttgagtga acttttgacg
     5641 tcctgtgtag aatgggtgtg aatctgatga aatttccaca cggataagtg ggtaagtttc
     5701 accttcaaac tcaacagttt ctttagaagc ttttgttgag ccgctaagga actggtaacc
     5761 tgtagttgta tcaaggaaaa caactggacg ataatctgga tgaatgtctt ttctcatctt
     5821 aaaaaattcc tttctgccat gacacttgat gcgtcatagt tattaactat tctagtgtaa
     5881 caaaacttga atgacttgac aaggcttttc tttccttatt ttttaaaaat cctaaatctc
     5941 ttggcaaaca gcgatgagtt ctcggaaaat agcttgattt tcttctaaat tagctgagtt
     6001 ggctccgcta gcaaggggat gcccccctcc accgtgacgc ttagcaatgc cattaataat
     6061 cttttcttta ctgcgcatac gcacacggta gttgccgtca gttaactcaa caaaaatagc
     6121 ccaagcttga acgttatcaa ttttaccagg agcacagaca atggcagagc tttctgctag
     6181 ggtcacgtca aaatgtttta aggtttcttg gctgacaagg acataagcag ccccactctc
     6241 atcaattgtt aaatgctcaa agacgtagct ttgcagcttt gctattttca aaggaaacga
     6301 atccatttgc cttgaaatcg cagcaaagtc gaactcgaaa tgtctgagtt ggctagcaat
     6361 ggaaagggtt ttactagtgg ttgaggcata aagaaatcgc cctgtatcac caacgatacc
     6421 agtgtataag agcttagcag ccttgtcaga gagagtaaga ttctgactaa aggcaaagtc
     6481 tgcaatgatt tcacttgcgc tagaagcgct tgtgtccaca taatagaagt caccatacac
     6541 atcatcgttg ggatggtgat caatcttaat taagcactgc cccagtgtgt agcgctcatc
     6601 atcaatcctt ggtcgattcg ctgtatctgt aatgatgacc aaagcctctt tatagtcttt
     6661 gtcagtcacc tgatccattt ggctaatcca agctaaacta ggctcatcaa aaccagtcat
     6721 taaaaccttt ttgtctggga aattttgtgc aataatttct ttcaagccgg cctgactacc
     6781 aagagcatca gggtcaggat tttgatggcg atggataata atagtttggt gggcttttat
     6841 tttatctaaa attgtttcaa aagttgttat catgctttaa tctttctttt tcaaaaagag
     6901 gaaaataacc gtttaacata gtcttcaaaa aacggtttgt gtcataagga ggtgtgcgtt
     6961 atgttaagtg gctaatgcta gaatttttta agattgtcaa agaccataaa ttgacatttt
     7021 atctgaaaat catatcctat tttattatag cataaaagta agctctagat aatggtaaat
     7081 taatctagga agaaaagagg ttagttatca gttatgatac tatcaaagct agtcttgcaa
     7141 atgcaagtga aaaaatagtt tttaagtgtt ttaagtaatc atatcaacct tctcgttaaa
     7201 caattagtgc ttttcctaaa aaagtgtgtt aaaataaaca tagtttagta attttgggag
     7261 gaatttatgg cattagcaaa aatcgtttat gccagcatga cgggaaatac tgaagaaatc
     7321 gctgatatcg ttgcaaataa attgcaagaa ttgggccatg atgttgacat tgatgagtgc
     7381 acaacggttg acgcttcaga gtttgagaat gctgatatcg ctgtcgttgc gacttatact
     7441 tatggtgacg gtgacttacc agatgaaatc gttgattttt acgaagattt acaagattta
     7501 gatttagaag gtaaaatcta tggcgttgtc ggctctggtg acacttttta tgactatttt
     7561 tgcaaatctg ttgatgactt ttcagagcaa tttgcgctta ctggtgccat caaaggtgca
     7621 gagccagtca aagtagattt ggcagcagaa gatgaagaca tcgatcgttt agaggccttt
     7681 gcagagcaac tctcacaggc tgttaataat ctataaaact atttagtaaa aatgtcaggg
     7741 acttccttgg catttttaga tttttaacct aaaataaagg gaatgtcact tcagggtagg
     7801 aattgaaaaa aacaatcagc ttcaccttgc ttctgatcct cttattaact ataataaaaa
     7861 gataatctaa tacatctaga aaaggaaagt tatgcgttta gaagagatac gacaagaaat
     7921 caatagtatt gatcaccact tggttgcctt attagaaaag cggatggcac ttgtagagca
     7981 agtaacagct tataaactag ccaatcactt gcctgtctta gatcaggcga gggaaaatca
     8041 gatcctagat agggtttctt atctcgttaa agaccaagca tttgagccag ctatccatga
     8101 gacgtttaaa accattatgt ctctttcacg gcagtatcaa acgcaacgct taacaggtgg
     8161 tgacactaat gattaaatca attgcaacac tgcctaaacc ctccttaaaa gaagcgttag
     8221 gactaatagg cttggcgctt cccatagggg tcgcggttgg agtggttgat gtgatttttg
     8281 gtaaaggact tttgtttctt tccgagtatc gcgatcacca ccttttcttg cttcttcctt
     8341 ttcttgccct agcaggtctt gttatcgttt ttctttacga taagttaggc aaagaggttc
     8401 gtcaagggat gggattggtt tttcaggtag ggcatggtca aaaagatcag attcctccta
     8461 ttctcattcc tcttattttg ttctcgactt gggtaaccca cttatttgga gcgagtgcgg
     8521 gtagagaagg ggtagccgtt caaataggag ctaccatctc tcattattgt cagagatttg
     8581 tgactagtca agaagccgca cgacaccttt tgattatggg gatggcagcc ggttttgcag
     8641 gactttttca aacgccgatt gctgctgtcg tatttgccct cgaggtttta ttggtaggaa
     8701 cgcttcgcta ctgcgcttta ttaccttcct tagttgctgc ttgcgtggct tcttggacct
     8761 ctcattcttt gggattagag aaatttacga ttgttcttga agaaacattg accataactc
     8821 ccttaacctt agttaaatta attgggttag gtcttatttt tggtctggtg ggaaatagtt
     8881 ttgcctgttt acttggctgg tttaaacctt acctgagtca aaagctacca aatccttatc
     8941 tcaggattgc tttcattggt gttttgttat ctatctgttt gatgattggt cacgttggaa
     9001 gatatagtgg tctagggact catttgcttg cggcagcttt ttctggccaa actatcctaa
     9061 cttacgactg gcttttaaaa atgatcgtga cggtgattag cttatctgca ggctttcaag
     9121 gtggtgaagt gacgcctcta tttgctattg gagcttcttt aggtatcgtt ttggcccctt
     9181 acttaggtct tcctgtactg ttggttgctg cacttggtta caccacggta tttggaagtg
     9241 caacaaatac cttttgggcc cctatcttta ttgggataga ggtctttggt ccagagaatg
     9301 ccctagcata ttttgtcacc tcggctgcag cctatatggt tagtcacaga cattccattt
     9361 acagttatca aaaagtagtc atgatcaatt taaaagacat gacggtaaat cagatggatt
     9421 taaaaaaata gctttacaat aaagaagctt tttgttagaa taaatctcgt gtgtaatgga
     9481 cacacgaaaa ttacggctaa tccgctaaga caagtactta agattagtaa gataggagaa
     9541 taaaaatgaa tccattaatc caaagtttga cagaaggtca acttcgctct gatatcccta
     9601 acttccgtcc tggtgacact gttcgcgttc acgcaaaagt tgtcgaagga actcgcgaac
     9661 gtatccagat ctttgaaggt gttgttattt cacgtaaagg tcaagggatc tcagaaatgt
     9721 acactgttcg taaaatctca ggtggtatcg gggtagagcg tacattccca atccacacac
     9781 cacgtgttga caaaatcgaa gttatccgcc acggtaaagt ccgtcgtgcg aaactttact
     9841 acttgcgtgc attacaaggt aaagcagctc gtatcaaaga aattcgtcgt tagtttgaac
     9901 cgaaacgtaa cataatagaa taaaaagact agagtctcta gtctttttat gtcgtcgtga
     9961 caatgtgaca cttggtgatt aacgctatgc tcgtaggaca ctttgaaagt tccttagcag
    10021 ttataattag tatattgtaa taacaaaatg aagcaaaata aactttcagt tatctgatat
    10081 ttcatcttgc attaccttat tttctaggtt aaaatagaag acaaggtgaa tataagatag
    10141 gccccttagt tcaatggata taacaactcc ctcctaagga gtagttgctg gttcgattcc
    10201 ggcaggggtc attattgtca ctgaaaaagc ctttacatca aaggcttttt gttttattcc
    10261 ggttctaaaa ggggcagttt gtttatttat aatttctttc atgtttacag ttgtgtgact
    10321 gtaaatagat aatgttgttt ttggatcgct gtgaccaact ctatccatta tcgcatttag
    10381 cggtatccct ttttctgcta aaaatgatat atgcgagtgt ctaaataagt gcgtgtgata
    10441 atctccgtaa attttcaatc gcttattgat gtacgcgttt aaaattggta aaccttttga
    10501 atatggaaag ctgttagcac tctgcttgtg attaatctat cgtatgttaa aagtgacatt
    10561 taaattaaat cattttttat acatatattt caacaggatt tatcatattg gaaaatagcg
    10621 gtgcttctat tggcatttta ctattgacag gaatttccct gccttttgtc tcctaaagaa
    10681 gatcagcttt gatttctaac ttgattagag tgggcttggt actgtttatg aattatcagt
    10741 gcatactttc tggagatcaa aaaggaaagg agcagctaaa gaggtgtatg tgttaccatt
    10801 agaggaatag agcatcgcaa gactcgttta ttcagtcatt acgatacctg ttttatttgg
    10861 gaaataacta taatattaag tgaatttgtg atataatgaa aggtatgaat tatcaagatt
    10921 atatatggga tttgggaggt accttactcg ataattacga gctttcaacc caagcttttg
    10981 tccaaacgct agcttttttc agccttccag gagatcacga tgctgtttac caaaaattaa
    11041 aagaatcaac cgctatcgct gtggcaacgt ttgctcctaa tgagccagaa tttttgcatg
    11101 tgtataggct aagagaagca gacaaattgg cacaacccat ttggtgtttg ggagctaaag
    11161 aaattttgga aaagatagcg acttcaggtt cgcgaaattt tttaatttct catcgagatt
    11221 gtcaggtgaa ccaactttta gagcaagctg ggttgttaat ctattttaca gaagtcgtga
    11281 cagcttcaaa tggctttgct cggaaaccaa atcctgaaag tttgttttat ttaaaagaaa
    11341 agtatgatat taatagtgga ttagtaattg gagatcggct aattgataaa caagcaggac
    11401 aagcagcggg ttttaatacc ttgcttgttg acggtagaaa aaacctattg gagatagtaa
    11461 cgtagatgat tgaagaaaat aaacattttg aaaaaaaaat gcaagaatac gatgccagtc
    11521 aaattcaggt tctagaaggg ctggaggctg tccgaatgcg tccagggatg tatattggct
    11581 cgacagctaa agagggtttg catcatttag tctgggaaat tgttgacaac tcaattgacg
    11641 aagcattagc aggttttgcc tctcatatta aagtctttat tgaagcagat aattccatta
    11701 cagtagtaga cgatggccgt ggaattccag ttgacatcca agccaagaca ggacgtcccg
    11761 ccgttgaaac agtttttaca gtcttacacg caggtggtaa atttggcgga ggcggctata
    11821 aggtttctgg aggactacat ggtgtagggt catctgttgt taatgcttta tcaacacaat
    11881 tagatgtgcg tgtttataaa aacggccaaa ttcattacca aaaatttaaa cgcggagctg
    11941 ttgtagcaga tcttgagatc attggaacca ctgatgtgac tggaacaacg gtacacttta
    12001 cacccgatcc agaaattttt actgaaacga ctcagtttga ttacagtgtt ttagcaaaac
    12061 gtattcaaga gttagccttt ttgaatcgtg gtttaaaaat ttccattaca gataagcgct
    12121 caggtatgga acaagaagaa catttccatt atgaaggtgg aattggttct tatgttgaat
    12181 ttttaaatga taaaaaagat gttatctttg aaacgcctat ctatacagat ggtgaattag
    12241 aaggtattgc agttgaagta gccatgcaat acacgactag ctatcaagaa acagtcatga
    12301 gttttgctaa taatattcat actcatgaag gtggaacgca tgaacaaggc tttagagcgg
    12361 ctcttactcg ggtcatcaat gactacgcta agaaaaataa aattcttaaa gaaaatgagg
    12421 acaatttgac aggagaagat gttcgtgaag gtttgacggc ggtaatttct gttaagcatc
    12481 caaatcctca atttgaaggt caaaccaaaa caaaattggg caactcagaa gtggttaaga
    12541 tcactaatcg tctctttagt gaggcctttc aacgttttct tttggaaaac ccacaagttg
    12601 ctcgtaagat tgtggaaaaa gggattttgg cttctaaagc tagaattgca gctaagcgag
    12661 cccgcgaagt cacccgcaaa aaatcaggct tagaaatttc aaacttacct ggaaaattag
    12721 cagactgttc gtcaaatgat gctaaccaaa acgaactttt catcgtcgaa ggagattcag
    12781 cgggtgggtc ggccaaatca ggtcgtaacc gagagtttca agctatcttg cctattcgtg
    12841 gtaaaatttt gaacgtggaa aaagcaacta tggataagat tcttgccaac gaagaaatta
    12901 gaagtctttt taccgctatg ggtacaggtt ttggtgcaga ttttgacgtg tcaaaagctc
    12961 gctaccaaaa gctggttatc atgaccgatg ccgatgtgga tggcgctcat attagaacct
    13021 tgcttttaac cttgatttac cgctttatga ggcctgttct agaagctggc tatgtttata
    13081 tcgcccagcc acctatttat ggtgttaagg tcggtagtga gattaaagag tatattcagc
    13141 caggtattga tcaagaagac caattaaaaa cagctcttga aaaatatagt attggtcgtt
    13201 caaaaccaac tgttcaacgt tataaaggtc ttggggaaat ggatgaccat caactttggg
    13261 aaactactat ggatcctgaa aatcgtttga tggcgcgtgt gacagttgat gatgccgcag
    13321 aagcagataa agtatttgat atgttaatgg gagatcgtgt tgaaccaaga cgtgatttca
    13381 ttgaggaaaa tgcggtttat agtacactgg atatttagtc acctttttag tttcacaagg
    13441 aatctgctac caaagaggac gaattgacta aaaatcatga tgcatgatgc caacagcttt
    13501 gttagttagt acgtcttcat cttgagggac agcgttaatg cataggtatt gagaccgccc
    13561 cttaatacct atgttagtcc ttattaagaa agccttttga gtcgctggta cgagattgtt
    13621 gaattagtca aatatatttt gaaatgcatt ttaaagtatg ttataatcgt aatgttatag
    13681 tgtattttaa ataaaatttt aataaaaggc gattgaggaa tttcagtttt tagttattac
    13741 tggaacaatg ttgataaatc gtgtctaaat aataaggaga ttcagatgtc aagcggaatt
    13801 atcttgctga ttgtggctat agtcctacta gtgattatcg cctatctagt gggtgtcatc
    13861 atacgaaagc gtaatgattc cctaattacc agtctagaag aacgaaaaca ggccttgttt
    13921 gctttgcctg ttaatgatga aattgaagaa gtaaagtcac ttcatttgat aggacagagc
    13981 caaacctctt ttcgggaatg gaatcagaaa tgggtagact taactgtaaa ttcgtttgca
    14041 gatattgaaa atcatatttt tgaagctgaa aatttgaatg atacgtttaa ttttattcgc
    14101 gccaagcatg agattaatag cgttgaaagt cagcttaatc ttgttgaaga agatatcgct
    14161 tctattcgtg aggcacttaa tatcttaaaa gagcaagaag aaaaaaatag tgctcgtgtc
    14221 acccatgctc ttgatttata tgaaaagctc caagcttcta tttctgagaa tgaagataat
    14281 tttggttcaa ctatgcctga aattgacaaa cagatgaaaa acattgaaac tgaattttca
    14341 cagtttgtcg cactcaactc atcaggtgat cctgtagaag cttctgaagt tctggataga
    14401 gcagaagagc atactattgc tctagggcag attacagagc agattccagc tattgtggcc
    14461 aagttggaag atgattttcc agatcagtta gatgatttgg aaacaggata tcgccgttta
    14521 cttgaagaaa actatcattt tccagaaaaa aacattgagg cacgttttca ggagattcgt
    14581 gagtctattc gtgccaattc atcagagtta gttacacttg acttggatcg tgctagagaa
    14641 gaaaacacgc atattcaaga acgcattgat tctctttatg aagtctttga gcgcgaaatt
    14701 gccgcttata aggtagctgc taaaaatagt aagatgctac ctcgttacct agcacatgtg
    14761 aaacgtaata atgaacaact caaagatgaa attgcacgtc tatcacgtaa atatattcta
    14821 agtgaaacgg aaagtctgac tgttaaggca tttgagaagg atattaaaga gatcgaagac
    14881 agtacacttg ctgttgcaga acaatttggt ttacaagaaa aaccattttc agaactgcaa
    14941 gtgacttttg aacgcagtat aaagacgctt actaatgtcg agtcaggtca aatggatgtt
    15001 tttgcagcag ttaaagacat tgaaaaaatt gaatcacagg cacgccataa ccttgatgtt
    15061 tatgttactc agcttcatat gattaaacgt tatatggaaa aacgtcactt gcctggaatt
    15121 ccacaagact ttcttagtgc tttctttaca acgagttcac agttggaagc tttgatggat
    15181 gagcttagta gaggacggat caatattgag gcagtgtcac gtttgttgga agttgcgacg
    15241 gttgctattg ctaatctaga agatttaacc tatcaagtgg ttcaaaatgc taccttgact
    15301 gaacaattac tacaatattc taatcgctat cgttcttttg aagcaggagt tcaaagtagt
    15361 tttgaacatg ctttgagact tttcgaagta gaaaatgatt atcaggcttc ttttgatgaa
    15421 atttcttatg ctcttgaaac agttgaaccc ggggtaacag atcggtttgt taactcttat
    15481 gaaaaaacac gagagcacat tcgtttttga tacttgaaag tcgtgatatt ctcacgactt
    15541 tttattagct ttttggacca atacgtgttt ttgactagaa tcttcttttt aatgatcaaa
    15601 agaagaagta gtaacagtgt tttttgctat tgagaggata gttatttttt caaaaatctt
    15661 ttccaaaagg atttggtttt ttcaggagtt tttttgctaa gttgatcgtt ttttgtctgc
    15721 tttaagatga cttctaaacg tgtttccttt agatttattg cgtggtcggt atgaaggata
    15781 aacgcaaaag gtgaagtcat atgcgtttct gtaataatag taacaggtaa atggttttct
    15841 tttgctaatt tcatatagag tatttgaagt tgaggtgcca gcttggaaga gatttttaag
    15901 tgtaaaggtt gatagactaa ctgaaggctc ggtaattctc ttttcaaata gtcttttact
    15961 gttttagttt gagcttcgtc taataaagca cttaaaacga ctcgttcagc atacgttcct
    16021 agatagtagc gttgctgctc aggatttaat cttctttctc cccaggctcc ttttaatagc
    16081 ttatcttcta aattagtcat agataccctc gcttctttat aatagtttct ttattatatc
    16141 gatttctaca ataaaatacc aatttgaaaa ttttcggtaa atgtgttaaa aaacaagaaa
    16201 gaaagtgatt tttcttgcaa aaaacaaagg aagcttttca tgagattgct ttttaagttg
    16261 attaaaggcc tagtttgtgg tattatgaac atgtaaaata ttaaaactca taaggagagt
    16321 attacaatgt caattattac tgatgtatac gctcgcgaag tccttgactc acgcggtaac
    16381 ccaacacttg aagtagaagt ttatacagaa tcaggtgcat tcggacgtgg tatggttcct
    16441 tcaggagctt caactggtga acatgaagcc gttgaacttc gtgatggtga caaatctcgt
    16501 taccttggtc taggtactca aaaagcagtt gataacgtta ataacattat cgctgaggca
    16561 atcatcggtt acgatgttcg cgatcaacaa gctatcgacc gtgcaatgat cgcacttgac
    16621 ggtactccta acaaaggtaa acttggtgct aacgctgttc ttggtgtttc tatcgctgtt
    16681 gctcgtgctg ctgctgacta ccttgaagtg ccactttaca cttaccttgg tggattcaac
    16741 actaaagttc ttccaactcc tatgatgaac atcatcaacg gtggatcaca ctcagatgct
    16801 ccaattgcat tccaagagtt catgatcatg ccagttggtg cacctacttt caaagaaggt
    16861 cttcgttggg gtgctgaagt tttccacgct cttaagaaaa tccttaaaga acgcggactt
    16921 gttacagctg taggtgacga aggtggattt gctcctaaat ttgaaggaac tgaagacggt
    16981 gtagaaacta tccttaaagc tattgaagca gctggttacg aagctggtga aaacggcatt
    17041 atgatcggtt tcgactgtgc atcatcagaa ttctacgaca aagagcgtgg cgtttacgac
    17101 tacactaaat ttgaaggtga aggcgctgct gttcgtacat ctgcagaaca aatcgactac
    17161 cttgaagagt tggttaacaa atacccaatt attactatcg aagatggtat ggacgaaaac
    17221 gactgggatg gttggaaagc tcttactgaa cgcctaggcg gacgtgttca attggttggt
    17281 gacgacttct tcgttacaaa tactgaatac cttgctcgtg gtatcaaaga aaatgcagct
    17341 aactcaatcc ttatcaaagt taaccaaatc ggtactttga ctgaaacttt tgaagctatc
    17401 gaaatggcta aagaagctgg ttacactgcc gttgtatcac accgttcagg tgaaactgaa
    17461 gattcaacaa tcgctgacat cgcagttgca acaaacgctg gccaaatcaa aacaggttca
    17521 ttgtcacgta cagaccgtat tgctaaatac aaccaattgc ttcgtatcga agatcaactt
    17581 ggtgaagttg ctcaatacaa aggaatcaaa tcattctata acttaaaaaa atagacggta
    17641 agacagaaat cggtcattcg tagaatgcga tttcgtcgtc gcacctccgt caggctgact
    17701 aggttggtca cgacaaaagg agtggacatc cagtcagcta cgacgcaaaa gttaaagatt
    17761 aaagaataga aagcttggga aaatcccaag ctttttgatt tctaaatagt gaaaatttac
    17821 tgtggactaa tttatcctga gctaatgtat tagcgaggta aagttattga ggaaggcttg
    17881 gatttgtact gcccccaaac agttggacac tatattttaa atacagaact aagtcctttt
    17941 ataccaattg tcaagcacat caaggtttta actgaaaaaa tgttttagac aatagcctag
    18001 gtttagctgt tgtcttactt gttgtgctct gattagcata aaaaagtgta caagaaaaaa
    18061 accttgccta gtatttttaa gatcaaggtg ttacaatgat agagcaacaa cgactttaat
    18121 gattttgggt cgaagcgtaa ttgtaaagtt tgttatgcgt tatgaggtaa agcattgtcc
    18181 tgacaaggca atgtctagag gcaatcgtat gtggcttggt tgaagctgtt tgcgattgcc
    18241 tttttcgttt ctcatagaag tctgcgatat gacaaggatt ggtatgacta gcagaagcaa
    18301 tgtcatggat acacttgaaa agaatctttg gagcataagg attccaacgt ttggtaatgt
    18361 gctcttgagc tagatagttg ccagactcat aatgtctaaa gtcaatccca atgaaagcat
    18421 taatttgatt agcagattga aaacgacgaa tagcaccgag ttcgccaata atacttgttg
    18481 cagttgtttc tgcgatactt ggaatagagc gtagaatctt gtcttctggt aaaggttgag
    18541 ccaacgccac catcttatca aaaatagctt gacgacgttc agaaagtcta agtaattctt
    18601 tggcatagca acgaacctct tctatcatcg gagaggtttt cgtaacagta aaataagact
    18661 gcttggctaa tgagacaagt ttttccacta agtagatccc acacttgtca gagatacgtt
    18721 tagaggtaga ttgacggatg atagctgaca atgctttgtc agctagctct agtacaaagc
    18781 tattacatgg aaaagccgtt accacattcc agtattactc accagttggt gcaaataaga
    18841 tgtgttccag ttcaggaaaa gtgacttgta agatcttgtg aaggcgattc ttaactctcg
    18901 aacaatatta tcctcagtca atttttgata gaagcgactc aagtcacgta gcagctgata
    18961 aacttcttcc tgaacgtaag ttggttttct aactagaata aattgagact gagccaattt
    19021 ttcagtgtct aacttatccg ctttacgcac ccgtagacta tctagttttc taaaggattg
    19081 agttgtgtat aagcgtagcc atttttctca aggaaggact gaagccgacg agaatagact
    19141 cctgttgtga tggtctccct tttgcctttt aaacaatagt atagccgttt ttcaagatgt
    19201 tattaatgat tttttccttt attctagaag aataagtctg atactgtttc ttcttaataa
    19261 tctcaatgcc ctaacagtcc atcagtcgaa cggtatttct caaattactg cagttgactc
    19321 ttgcgttcag ttccctcacc ttgtggatgc cgtttagaac aatattagct tgctgagcct
    19381 tttggtaatg tgaacaaagc atctttatca ctcaaggaga agacaggttc ttgtggtaag
    19441 tgtccaacaa ggtcacgata aactcatcgt accgtttttg gcggaagtct agaaatgcct
    19501 tatgaatgta agcctcagaa acgtctctaa aactaaacaa gaaatacaag aacaaatgcc
    19561 cttgattctg gtacaaatgc tgtatcaggt tcaggtattg cctatctgcg ataatgacac
    19621 tctgcttttc cttaacaata tctttgaaag gaatgatttc gacattgaca ggcataaccg
    19681 ttgcaatagc tggcgggaag taaatcgaga gtgcattggt catcaaatcc agcgcagcag
    19741 tgttattggt caaaagatag acaggtatcg gtggcaaata tgtttttagg agttcctcta
    19801 actgtatcgt gaagagcagt aaatgatagg acggcagttt ccccacgatg ccttctgcgc
    19861 tcatccattc ctcaacgatg gtttttagag tattgtagaa gctcttgttt cgtttttgct
    19921 gtcttctgag gtaatggaac aagtgtatgt caggtaacaa aacttgaaga ttactgataa
    19981 agagacgtga gaaggaaacc aaaatccgtt tgaaaggaag ggattttagg atattattgc
    20041 ctagtagtgg acgcagggat gctttcaagg tttttccaat tgtttttgtc atcaccaact
    20101 caaacaattc tttcactttt ttaggtgtcc atttatcctt atggaaagga ttattggtgg
    20161 tgcaaaaaca taagaaaata taatccaaat cctcatcagt taaatcagga tggtaccatt
    20221 ttccgatgat ttcctgactg gtcattttga tatcgtgata gatagacagt tttttcaagt
    20281 gtttgaatgc atctgtctga gggatcccca agttatcatg tcgccgtttc catataaggg
    20341 atatcagaat ggcaaagtac gaaaattcat aaggggcttt actggcatca ttaagtgtga
    20401 tggcttgatt ggagtttata atcagcgaaa ccactttatt cattgatgtt ttatcaaaat
    20461 cataaatggt cataccaaac tgatagtgca acaaggcgat cagaaagcgg atacggtatt
    20521 ttggtccaac aacatggttt tgccgaacgt ttaaacctac ctttttcaag tatttccgac
    20581 aattggtcct gatacggtaa gcggtggctt gggaaatata ctctcgttta atgaagtcgt
    20641 gtaggctcag ctctcctggt tcaattaaaa aacataatat ctttaagaat atcgaggttt
    20701 gatagagttt cttaaaataa ggcattttaa gttggtaggt cttatagggg atagaaacag
    20761 tgtcgtcaca aatggttaag gtgagggtgt cttctaaatc cttaatcatt tcaaagagta
    20821 agttgtagac acgttgtttt ttgagttctg tttcctgaca caactggtct atggagactt
    20881 cggaaacgtc taacaaaatg ttgagcagtg ataatttatc ttgtaatttg gtttctagat
    20941 gaaggtgtaa cataactgaa ctcctttcat ttttatagca gaaactcgta tttatttaat
    21001 tatcacataa ttaaataaaa cagtcaaata attcaatggt gacgcgtgtt taaggagtat
    21061 tgagaatgtc agatataagc aaaatgcagc tgaatattct taattttagg tatgaaaaag
    21121 cgtcgggatt gataaaaaat ctattgaatt gggtaaattt aagttgatat aataagttga
    21181 ttagaaaaat taataattca tttaaattct aatcagctgt aacgttccgg ggcatgttaa
    21241 actgtctgaa tatagaaaat acaggtttct aaggtgacta agataagtta aggaggattc
    21301 cttaaattct gtgataggaa cgtaaactct ctacaagcgt agagcacgtc atcagtcagt
    21361 ctgggtgtct actggctgac aacgtcaaat aagataggca tgaaaaaata agggggaaca
    21421 cagaatgttt ttaaaacacc aagatgtgaa acaaaaaaat tggagaatgc gtaaggtcaa
    21481 aaaactcttt gttagttcat gtatgctttt aacagtcggc ctcggagttg ccgtacctac
    21541 tggattcagc caatctaatg gcgtgatggt tgtaaaggct gatgttacac aagaaggaag
    21601 tcctgaaaat gttttgaaga tagctaattc tttaaaggct acaactgatg gtacaaaaat
    21661 aggtagatat agtgcaataa atactcaaaa tctagatgtt tctgaatata aattttatta
    21721 tgttaactca actaaattaa ataaaaatcc tcaacaacgc ttatggcact atgaaaaacc
    21781 aaaagaaata tatgattcta ccattcgagt tgcgggtgat ggaactgcta atattcgttt
    21841 ttatgcagat ggagatggta gtaagactcc taatggattc tcttttgcat ataagttcaa
    21901 tactactaat ctaaaaacag accacaaata taagttgtcg ttcaagcaaa ctcaaaataa
    21961 tgacgaagag gtttatacaa agtatctggt aggtaaagca agtgaaggtg tcgctaatta
    22021 tttaacatct gaagaaactt cggtagctcg gaatgttgag ttatttgaag gtaatcaaaa
    22081 gacgactgca gagagaaaat ttgcaaaaca tcaatcagga gagaaatctc ttcagtttat
    22141 ttcaaaaaca gatggaactg ctagtttagt tttagcagct ggtgtaaaaa atactcccaa
    22201 gaaaaataca gatataacct ttgacagttt tgaatttatt gatataaccg aaccagctca
    22261 agttagttct ggagaagcga ttgcaggaaa taaaaatctt acggtaaatc taagtggttc
    22321 agacggtaga aaaaacttca gcggggaaat cattgaagtt tataagaatg gacaattatt
    22381 aaaaaaagaa acagtaacta cggcgggtaa taaagttaat attgctttga gtgatgatgt
    22441 tgttttgaaa aaagatgatg aaattacctt taaagtaaag caaggtagtt ctgggaaaaa
    22501 gaatcaagcg gcaggaaaaa ttattgttca acaaaatcca gcagttgtag cggagcaaga
    22561 aaactctaaa aaaagcttag aagaagtata taacaaagct aagaaagcta tttctgatga
    22621 tgagtggtta tcggatgagg aaaagagagt tcagactgca gcagttgaaa aaacttataa
    22681 tgaaggtcag acttcaatta ataatgcaga aacagtgact gaaataaagg atgctttcaa
    22741 aaaatattct acgcaaggta ataaaatttc tatacctgat caatataaaa aaggcgaaaa
    22801 agctataaaa caagaacaag ctcgaaaaag tttgaagcag gtacacgaag atacattagg
    22861 aaaaattaga tcagatgatt ggttgactga agaagaaaaa gcaactcaaa cagagaatgc
    22921 aaaacagagt tataatcaag gagagaacaa gattaatcaa tcagattctc tgaagacatt
    22981 aaatcaaata ttaaaagatt atacttctga ggaacccaat aaaaaagaat caatacccaa
    23041 caagtatgaa aaagggaaga aagaagaatt aaaaagagac gctgaaacaa aattaagaga
    23101 agctcaagaa actactaaac aagctataga aaatgatcca tggttgagtc cggaacagaa
    23161 aaaagctcaa aaagagaacg ctaaaacaag attagatgca ggtttaaaag ctgtcgaaac
    23221 tacagaaagc ttagataaac ttaaagaagt tgagagtgac ttccttgata aagaaaaagc
    23281 agaatctatt ccatctcaac atcaagcagg aactcctgaa gttgctcgca aaactttctt
    23341 agataacttt gaaaaagaag ctaaaaaaga gattgaatca attaaaaatg acgctacatt
    23401 aacagatgct gaaaaagcaa cagctaaagc taaagtagaa gcacaacttc aagaagctaa
    23461 agataaggct aaggaatcaa aatcgtttga tgatttgaag aacattcaag ataagttcaa
    23521 ttctgaatta ccacacacaa caggtaagcc gcttaaagat caacaatctg atgctattgc
    23581 agaattagag aagaagcagc aagaaattga aaaagctatc tcagaagata agacattgtc
    23641 aaaagatgaa aaagagaaac aaattgctga ttctaaagcg aaattagtcg ctgagaagga
    23701 aaaagtttct aaagcacctg atgctgatgc tgttaagaaa gctcttgagt taggtaagca
    23761 agaaattgct aaggcttatg ttccacaaaa cttagaagat cacaagaaaa aacttcttgc
    23821 agagttgaag caaaaagcaa atgatactga aaaagcgatt gatttcgata aaactttgac
    23881 agcgaaagaa aaagaagagc aaaaagcgaa aacaaaagaa gaacttcaaa aagcaacaga
    23941 agctgttgga gcaattgaca atcgtgaaga actagataaa aaagtcccag aacttaagaa
    24001 agctattcaa gattctcacg ttaaaggaga ccttgaaggt gttaagaata aagctattga
    24061 agatcttcaa aaagttcatg acgaaacagt tgctaaaata aatggtgatg atacccttga
    24121 caaagctact aaagaagctc aagtgaaaga agctgacaaa gctttggcag caggtaaaga
    24181 tgcgatcact aaagcagatg atgctgataa agtgggtgca gctgttacag agcacacacc
    24241 aaaaattaaa gcagcacata aaactggtga tcttaaaaaa gttcaagaag aggctaacca
    24301 agctcttgac aaagcagctg aaaaagaacg tggagaaatc aataatgata tcacattaac
    24361 ggcaaaagac aaagaacaac aactgaaaga agttgagaca gctcttacta aagctaaagc
    24421 taaagtggca gaagctaaga cagcagacgc tatcaatgac gcacgtgata aaggcgtagc
    24481 aacaattgat gccgttcata aagcaggtca agacttaggt gctcgtaagt caggtcaagt
    24541 cgctaaactt gaagaagcag ctaaagcaac gaaagacaag atttcagctg atccaacttt
    24601 gacaagcaaa gaaaaagaag agcaatctaa agctgttaac gctgaactta agaaagcgat
    24661 agaagctgtt aacgcagctg acacagctga caaggttgac gatgctcttg gtaaaggtgt
    24721 cacagacatc aagaaccaac ataagacagg tgaccctgtc gtagctcgtc gtgaggctca
    24781 tggtaagcaa cttgatagag tcgctcaaga aactaaagat gcgattgaaa aagaccctac
    24841 tttgacgact gaagaaaaag ctaaacaagt taaagacgta gatgccgcta aagaaagagg
    24901 catggctaag cttactgaag ctaagaatgc tgatgagtta gacaaagctt acggtgaagg
    24961 tgttacagac atcaagaacc aacacaaatc aggtgaccct atcgaagctc gtcgtggatt
    25021 acacaacaag tcaatcgacg aagtggcgca agcaactaag gacgctatca cagcagatac
    25081 gactttgact gaagctgaaa aagaaacaca acgtggcaat gttgataaag aagcaactaa
    25141 agctaaagaa gaacttgcta aggctaaaga tgctgatgct ttagacaaag cgtacggtga
    25201 cggtgtaacc agcatcaaga accaacacaa gtcaggtaaa ggtcttgacg ttcgtaaaga
    25261 tgagcacaag aaagctcttg aagctgttgc taaacgtgtc actgctgaaa ttgaggctga
    25321 tccaacctta acaccagaag tgagagaaca acaaaaagca gaggttcaaa aagagcttga
    25381 acttgcgact gataagattg ctgaagctaa agatgcagat gaagcagaca aagcttacgg
    25441 tgacggtgtc acagcgatcg aaaatgccca cgttattggt aaaggtatcg aagctcgtaa
    25501 agaccttgct aagaaagacc ttgctgaagc tgctgctaag acaaaagctc tcattattga
    25561 agacaaaacg cttactgatg atcaacgtaa agaacagtta ttaggtgttg atacagagta
    25621 tgctaaaggt atcgagaata ttgatgcagc taaggatgct gcaggtgttg ataaagcata
    25681 tagtgacggt gttcgtgaca tcctggcaca gtacaaagaa ggtcaaaacc ttaatgatcg
    25741 tcgtaatgct gccaaagaat ttcttcttaa agaagcagac aaagtgacga aactaatcaa
    25801 tgatgatcca accttgactc atgaccaaaa agttgatcaa atcaacaaag ttgaacaagc
    25861 taagttagac gcaatcaagt ctgttgatga tgctcaaaca gctgatgcta tcaatgatgc
    25921 tcttggtaag ggtattgaaa acatcaacaa ccaataccaa catggcgatg gcgttgatgt
    25981 tcgtaaagcg actgccaaag gcgatcttga aaaagaagct gctaaagtga aagctcttat
    26041 tactaacgac ccaaccttga ctcaagctga taaagacaaa caaacagcag cggttgacgc
    26101 agctaagaat acagcaattg cagcggttga taaagcgaca acagcagatg gtgttaacca
    26161 agaacttggt aaaggcatca cagctatcaa caaagcttac cgtccaggtg aagctgttaa
    26221 agcacataaa gaagctgcta aagtgaaagc tcttattgct aaggatccga ccttaactca
    26281 agctgataaa gacaaacaaa cagcagcggt tgacgcagct aagaatacag caattgcagc
    26341 ggttgataaa gcgacaacag ctgaaggcat taaccaagaa cttggtaaag gcatcacagc
    26401 tatcaataaa gcttaccgtc caggtgaagg tgttaaagca cgtaaagaag ccgctaaagc
    26461 tgatcttgaa aaagaagctg ctaaagtgaa agctcttatt actaacgacc caaccttaac
    26521 aaaagctgat aaagctaaac aaacagaagc tgttgctaaa gctcttaaag ctgctatcgc
    26581 agcggttgat aaagcgacaa cagctgaagg cattaaccaa gaacttggta aaggcatcac
    26641 agctatcaac aaagcttacc gtccaggtga aggtgttaaa gcacgtaaag aagctgctaa
    26701 agctaatctt gaaaaagtag ctaaagaaac taaagctctt atttcaggag accgttactt
    26761 gagcgaaact gaaaaagcag tccaaaaaca agctgttgag caagctcttg cgaaagcact
    26821 tggtcaagtt gaggctgcta agacagttga agctgttaag ttggcagaaa accttggtac
    26881 tgtagctatc cgttcagcat atgttgctgg tttagctaaa gatactgatc aagcaacagc
    26941 tgctcttaac gaagcgaaac aagctgctat tgaagctctt aaacaagctg cggcagaaac
    27001 acttgctaag attacaactg atgctaaatt gactgaagct caaaaagctg aacaatcaga
    27061 aaatgtatca ttagcgctta agacggctat tgcgactgtt cgttcagcac aatctattgc
    27121 gtctgtgaaa gaagcaaaag ctaaaggtat tgctgctatc cgtgcagcct atgtgcctaa
    27181 taaggcagtc gcaaaatcat cgtcagcgaa ccatcttcca aaatcaggtg atgcaaactc
    27241 aattgttctt gttggcttag gagttgtgtc tcttctttta ggtatggtgc tttatagcaa
    27301 gaaaaaagaa agtaaagact aaaaacctgg ctttatccaa attgctttct actatatttt
    27361 caaaccaagg tgattttgaa atcaccttgg ttttttggat cgtaagggcc caagaacgga
    27421 gtgtattgaa aacatttcaa agttcaattg aaaaggcaac agttttctgt acagaattta
    27481 taaggcgttt tttgttcaaa cgatgactca tttagttatg ggtgtttgat aattaagatt
    27541 actgcgaagg tgatggtagt tccaccagtg gacttcctcc ttggttttaa gggttaattg
    27601 ttctagtgaa taaaaggttt cttggtcgcg cagtagggat caagcgagca aataaaatgc
    27661 ctattttaaa tcagttcgag cgaattttcg tgctacaagc tcaaaagagg ctactaaagt
    27721 attagaacag tttatctctg agtgaagttc ttgttataag aagatgatgt tatcgtttga
    27781 aacgaccaaa aaatctccta acttttacta atttctacat gaaatctagt ccagcattta
    27841 ctccacaacc ttgattgatt cgcttaataa agacatttct acttgattgt ttacacatag
    27901 tt
//
LOCUS       DAUCXI010000022        27521 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.022, whole genome shotgun sequence.
ACCESSION   DAUCXI010000022 DAUCXI010000000
VERSION     DAUCXI010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27521
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.022"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..823)
                     /locus_tag="VGY43_001027"
     CDS             complement(<1..823)
                     /locus_tag="VGY43_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ4302219.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFVIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSII"
     gene            1067..2314
                     /locus_tag="VGY43_001028"
     CDS             1067..2314
                     /locus_tag="VGY43_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ4302220.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQVLFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFN
                     GKIKESDYLTKLQQFDKDIAATK"
     gene            2588..3949
                     /locus_tag="VGY43_001029"
     CDS             2588..3949
                     /locus_tag="VGY43_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ4302221.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPSFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            3949..4785
                     /locus_tag="VGY43_001030"
     CDS             3949..4785
                     /locus_tag="VGY43_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEQ4302222.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            4972..5788
                     /locus_tag="VGY43_001031"
                     /pseudo
     CDS             4972..5788
                     /locus_tag="VGY43_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(6260..7243)
                     /locus_tag="VGY43_001032"
     CDS             complement(6260..7243)
                     /locus_tag="VGY43_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ4302223.1"
                     /translation="MVIIAVVIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGMQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTAPQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDYEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEHT"
     gene            complement(7274..8524)
                     /gene="dltD"
                     /locus_tag="VGY43_001033"
     CDS             complement(7274..8524)
                     /gene="dltD"
                     /locus_tag="VGY43_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEQ4302224.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDETCRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(8517..8756)
                     /gene="dltC"
                     /locus_tag="VGY43_001034"
     CDS             complement(8517..8756)
                     /gene="dltC"
                     /locus_tag="VGY43_001034"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEQ4302225.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(8774..10030)
                     /gene="dltB"
                     /locus_tag="VGY43_001035"
     CDS             complement(8774..10030)
                     /gene="dltB"
                     /locus_tag="VGY43_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEQ4302226.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAMAL
                     FPLIWVKVVPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(10027..11565)
                     /gene="dltA"
                     /locus_tag="VGY43_001036"
     CDS             complement(10027..11565)
                     /gene="dltA"
                     /locus_tag="VGY43_001036"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEQ4302227.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELASGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(11577..11720)
                     /locus_tag="VGY43_001037"
     CDS             complement(11577..11720)
                     /locus_tag="VGY43_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEQ4302228.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            complement(11984..13975)
                     /gene="uvrB"
                     /locus_tag="VGY43_001038"
     CDS             complement(11984..13975)
                     /gene="uvrB"
                     /locus_tag="VGY43_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEQ4302229.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
     gene            14168..16342
                     /locus_tag="VGY43_001039"
     CDS             14168..16342
                     /locus_tag="VGY43_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEQ4302230.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPIKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATITDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDVVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            16342..17082
                     /locus_tag="VGY43_001040"
     CDS             16342..17082
                     /locus_tag="VGY43_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302231.1"
                     /translation="MTELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVMVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEVAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(17230..17382)
                     /locus_tag="VGY43_001041"
     CDS             complement(17230..17382)
                     /locus_tag="VGY43_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302232.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
     gene            complement(17379..18758)
                     /locus_tag="VGY43_001042"
     CDS             complement(17379..18758)
                     /locus_tag="VGY43_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEQ4302233.1"
                     /translation="MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGASSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNITITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLIWAPFVILA
                     NKEKASDLA"
     gene            complement(18936..19385)
                     /locus_tag="VGY43_001043"
     CDS             complement(18936..19385)
                     /locus_tag="VGY43_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEQ4302234.1"
                     /translation="MIISAEGDVSIHHCFEAMLISLQEDYRQNTLRQLSRDDIKAGIN
                     YVKHYGKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYQLEALGENRTRITYSYD
                     YHPLDIFQKANQFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            complement(19382..19717)
                     /locus_tag="VGY43_001044"
     CDS             complement(19382..19717)
                     /locus_tag="VGY43_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ4302235.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            complement(19720..20031)
                     /locus_tag="VGY43_001045"
     CDS             complement(19720..20031)
                     /locus_tag="VGY43_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEQ4302236.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EVAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            complement(20054..22048)
                     /locus_tag="VGY43_001046"
     CDS             complement(20054..22048)
                     /locus_tag="VGY43_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEQ4302237.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVSQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNIFLEGINFAEIMIIVLDECRDAKLKLSDFVI
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLAH
                     MMPLITRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LSKAEQLLTGVFSPNRFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVSICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            complement(22154..23248)
                     /locus_tag="VGY43_001047"
     CDS             complement(22154..23248)
                     /locus_tag="VGY43_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEQ4302238.1"
                     /translation="MVDLGFSLYPERYDVTKSKAYIDLCHSYGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAERSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFITAQSASEGPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEQIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVREDYLSLLDDLRPWQEFCLEIDPS"
     gene            complement(23257..24657)
                     /locus_tag="VGY43_001048"
     CDS             complement(23257..24657)
                     /locus_tag="VGY43_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEQ4302239.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWDYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMTPAYPRSNAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGK
                     KVNPHRGWEIYEPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            24882..25577
                     /locus_tag="VGY43_001049"
     CDS             24882..25577
                     /locus_tag="VGY43_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEQ4302240.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILVTLIFYGILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDSSQYAVVICFATFLINDSYTFYSWL
                     MLQRYQEKKVKKG"
     gene            complement(25582..25740)
                     /locus_tag="VGY43_001050"
     CDS             complement(25582..25740)
                     /locus_tag="VGY43_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302241.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(25809..27122)
                     /gene="obgE"
                     /locus_tag="VGY43_001051"
     CDS             complement(25809..27122)
                     /gene="obgE"
                     /locus_tag="VGY43_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEQ4302242.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDMPEAQENLKAFKKKLATQYDEFNDLPMIFPISSLAHQGLENLLEATA
                     ELLAKTDEFLLYDEADLVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDPVRIGKFEFEFVD"
     gene            complement(27179..27307)
                     /locus_tag="VGY43_001052"
     CDS             complement(27179..27307)
                     /locus_tag="VGY43_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEQ4302243.1"
                     /translation="MAFGENGPRKKTTFEKVTMVVVILMVLVTVGGLIASALSVLM"
BASE COUNT         8560 a         5698 c         4791 g         8472 t
ORIGIN      
        1 tgataattga catatcatct ggcactttta tatcataaaa agataataac tgtaccatac
       61 gaatagccag aacatcacca acaacaacca aggcagttgc tttaaaggaa gatatagttt
      121 ccatcaatat ttctacgcta acaggatcct tacgatcaaa taacagcatt ggcttcgttt
      181 ttaaagatcg cttaaaacaa cccttcaaat agccaagata acgctcagaa gttacttctg
      241 atagtaaatc atctgttata aataatatgt tgtgatggcc tttttgataa aggtgttcta
      301 ctgctgtttt agccattagc tgattatcat tatcaatata agtggtttta ttagtgtcac
      361 cttgtggagc acctacaatg acaaatggta agttatttgt catcaaatat tttttgacag
      421 gatcatcttg atcagaataa agaataataa aaccatcaac tcgtttttga agatgcatca
      481 gtttcacttg ctctatcagg tcatcaagag atatacctgt agcaatcgac acagtaaaat
      541 gagattcttt agcttcgtta gtaatagtcg acaaaatttc cataaagaaa ggttcactta
      601 atctatcgct agttgtaata ggaggaaaaa caagtcctat attgtgtgtc aaaccactcg
      661 ctagaatctg tgctgcgaca tttggaacat atcccaaatc tgccatcgct tttctaacct
      721 tctcttttgt tttcatagaa atagatcgat tatcttttaa taccctactc accgtcgaag
      781 ggttaacacc tgccttttga gcgacatctt ttattgttac catattaacc tcgttactat
      841 atttaccaaa gataaacctt atcatgggtt tgtcatgtat ttcgtttcca ttatacaatt
      901 atctttcaaa aaatcaactt caatcaagat tcccttgtca ttttaactca aattctctaa
      961 actatttttt aaaaaaaacg accttttttt aaaaaaaggc ttgacttttt ctgcaagcgg
     1021 ttgcataata ttaagtgtaa gaaatatacc ttaggaggaa atagctatga aatcatggca
     1081 aaaagttatc gtcggcggag caagtttgac acttgcaagt accttgttag tgggatgtgg
     1141 atcaggttca aaagataaaa aggaagctgg cgctgactca aagactatta aactttgggt
     1201 accgactggc tctaaaaaat catatgcaga taccattgca aaatttgaaa aagattctgg
     1261 ttacaccgtt aaagtggttg aatcagaaga tccaaaagca caagaaaaaa tcaaaaaaga
     1321 tgcctcaact gctgccgatg tcttttcact tcctcatgat caacttggtc aacttgtaga
     1381 atctggtact attcaagaag ttccagaaaa gtacaataaa gaaattgctg ctacttctac
     1441 tgatcaggcg ctcgtcggtg cacagtacaa agggaaaaca tatgctttcc catttggtat
     1501 tgaatcacaa gttcttttct acaataaatc aaaattagct gctgaagacg ttacttcata
     1561 tgatacaatt actacaaaag caacttttgg tggtaccttt aaacaagcta acacttacgc
     1621 tactggtcca ttattcatgt cagttggtaa cactttattt ggggaaaacg gtgaagatgt
     1681 aaaaggtact aactggggca atgaaaaagg cgctgctgtt cttaaatgga tcgcagacca
     1741 agcttcaaat aaaggttttg ttagcttaga tgctaacaac gttatgtcta aatttggtga
     1801 cggttcagta gcttcttttg aatcaggacc gtgggactat gaagctgctc aaaaagctat
     1861 cggtaaagaa aaccttggtg ttgctattta tccaaaagta actattggag gcgaaacggt
     1921 tcaacaaaaa gcattcttgg gtgtaaaact ttacgcagtc aaccaagcac cagctaaagg
     1981 tgatacaaaa cgtatcgcag ctagctacaa attggcatcc tacttgacta atgctgaaag
     2041 ccaagaaaac caattcaaga ctcgtaacat tgtcccagcc aacaaagaag ttcaatcttc
     2101 agaagctgtt caatcaaacg aacttgctaa aaccgttatc actatgggtt cttcttcaga
     2161 ctacactgtc gtaatgccaa aacttagcca aatgggcaca ttctggactg aaagtgctgc
     2221 tattcttagt gatgccttca acggtaaaat caaagaaagc gactacctta ctaagttgca
     2281 acaattcgac aaagatatcg ctgcaacaaa ataatatgat ctcatgtcat cactgctata
     2341 ctaaaacaag cacaaggtaa gtacttctaa aaagttcttt ccacttacct tatgaagagt
     2401 ggaactaggc tccatcacat tttattcaag cttagtctca ctcttacttg tttttgtttt
     2461 actagtagct tagtgctact taaattttta actctttaaa agtttacgta acacttagct
     2521 atttcatcct aacaagagat tgaatctgaa ctaccactct agtatcctaa aataaaggag
     2581 aatctatatg actcagtcaa acttgacacc aaatatatct gtaatagaag ctttaaaaag
     2641 aggcagttgg gatattaaac tttcgagtat tatcatggga tttgccaact ttgctaacaa
     2701 acagtttatc aaaggaatct tatttttaat aagtgaactt atctttctag tagcttttgt
     2761 ctcccaaatc atccctgcta tccgtggcct tgtcactctt ggtactcaaa ctcagggaat
     2821 gactacaaaa actattgatg ggattaacat ccaagttgct gttgatggcg ataactctat
     2881 gttaatgctt atttttggtt tagcatcact cattttctgc ctagtctttg cttacattta
     2941 ctggtgtaat ctcaaaagtg ctcgtaacct ttatcttttc aaacaaaaag gtcagaagat
     3001 accaagcttc aaagaagatc ttgccacact tacaaatggt cgctttcata tgactttaat
     3061 ggctatccca ctgattggtg tgcttttatt caccattctt cctttgattt acatgatctg
     3121 tttggccttt accaattttg atcataatca cttgcctcca aaatctttat ttgattgggt
     3181 gggacttgct aactttggaa atgttttaag cggccgtatg gcaggaacct tttttcctat
     3241 cttctcatgg actttgattt gggctgtttt tgccacagta actaatttct tctttggtat
     3301 tattcttgct ttgttaatca ataccaaagg attaaagtgg aaaaaaatgt ggcgaaccat
     3361 ctttgttatc accattgcag ttccacaatt catctcatta ttgattatgc ggaacttact
     3421 caatgacgaa ggcccactga atgctcttct caataaaatc ggcttgatta atggctcact
     3481 gccattttta tctgatcctc tttgggcaaa attctcaatc atttttgtca acatgtggat
     3541 cggtattcca tttaccatgt tgattgcgac tggtattatc atgaaccttc caagtgaaca
     3601 aattgaggct gctgaaattg atggcgctag caaattccaa gtcttcaagt ctatcacatt
     3661 ccctcaaatt ctcttgatca tgacaccaaa cttgattcaa caatttatcg gaaatatcaa
     3721 taactttaac gtcatttacc tccttactgg tggtggtcca acaaattcag aatactatca
     3781 ggcaggaaca acagacttac tggtcacttg gctctataaa ttaaccgtca cagctgctga
     3841 ctacaattta gcttctgtta tcggtatctt aatctttaca gtttcagcta tctttagctt
     3901 acttgcttat acaaggacag catcctacaa ggaaggagcg gctaaataat gaaaaacaaa
     3961 cgtcgatttc aacttggact tgtttatgct actttaatca tcctctcaat catttggctc
     4021 ttcccaatcg cttgggttat tcttactagc ttccgtagcg aaggaactgc ttacgtcaat
     4081 tattttattc ctaagacttt tacattaaat cactacatta atctttttac taatgaaacc
     4141 tttccttttg gaaaatggtt tatgaatact cttattgtag ccacttttac atgtattatt
     4201 tcaaccttca taactgttgc catagcctac tctcttagcc gaattaagtt taagtttcgc
     4261 aatggctttt taaaactagc ccttatttta aatatgttcc ctggtttcat gagcatgatt
     4321 gccatctact atatcttaaa ggccttaggt ttgacgcaaa ccctaacagc acttgtcctt
     4381 gtttattcct caggtgcagc ccttggtttt tacattgcaa aaggattttt tgataccatt
     4441 ccttattcac ttgatgaatc agctatgatt gatggcgcta ctcgtatgga tattttcttt
     4501 aaaataaccc ttcctttagc aaaaccaatc attgtctata ctgcccttct tgcttttatg
     4561 gggccttgga ttgactttat ctttgcacaa gttattttag gtgatgctac aagtaaatat
     4621 accgttgcta ttggactatt ttcaatgctt cagccagata ccattaacaa ctggtttatg
     4681 gccttcactg ctggttctgt cttaattgcc gtcccaatca ctctcctctt catgtttatg
     4741 caaaaatact atgttgaagg catcacaggt ggttctgtta aataagttac aacataccaa
     4801 accttctaag ggcaagccct ttaggaggtt tttgataaat aaggccgtag ataatcatat
     4861 tagtcctcac atttatcttc agatcccgcg ttgtaaaatg aagtgcaaca aaaaagacat
     4921 gttcgtctga tatactagaa ttccccaatt cagtatggaa agcagatgaa catgtctaat
     4981 attaattcta ccagaaaatc ctcctattct catctttcag ccacagaacg gggtgaaatt
     5041 gctgcttatc ttaaaatggg aaagaaaccc gttgagattg ctcgacttct gggtagtcac
     5101 cgttctacaa tctgccgaga aataaaacgt ggttcagtag atcaggtaaa ggataagaat
     5161 ggaaaacaaa ccttcttcaa cgcctatttc gctgatagtg ggcaacgtgt ctattaaacc
     5221 aatcgatttg cctaagatgg ttagtatcag aaaacgttct aagaaagtca tgaaaacgaa
     5281 taagaagact ttaggtaaat ctatcgaaga acgtccagaa tatattaatg atcgttctga
     5341 atttgggcat tgggagattg atttgattct cggcaagaaa accaaaggtg aagctgttat
     5401 gttgactttg gtagagcgcc agacacgcta tgcactagga gttaagctag aagacaagca
     5461 gtcccaaacc attaaccgcg ctgtcacgca tctcatcagt cagtatccta ttgcatccat
     5521 cacagcagat aatggttctg agtttagttt actctcaacc ttagaagctg ttgacgttta
     5581 ctttgcacat ccctattctt cacatgagag aggaacaaac gagaacttca atggcctcct
     5641 cagagaatat gtccctaaag gaatctcact taatccacta acctctgaag aacttgacaa
     5701 ttatcttaca gccatcaatg agcgcccaag acgacttctt caatatcaat cctcaacatt
     5761 cctgtttgag ctagcccgaa cagcttaacc tctggaactc tagttatcta tgaactcgtt
     5821 gcacttgact tgacaacttg cgagagcata tcagtagttt ttctgctaat tgaaaacagg
     5881 gtatttactg tcacacaagt ctgtcctttc tttttttcta caactttatt tcgtcagcgt
     5941 aaataaaaca aaagctctat aatctcttga atgggtaaat ccactgtaga gattatagag
     6001 ctttttgaat atcaaaaaag tcccataaga tttataatga aaagcaacca aactctcatt
     6061 agaaagactc ttatggaaca tatcaatcat accttacaac acatcggaat taaagacaaa
     6121 aatatcactc taaacaatgt tttgaaggat gaatctccta ctgagctcgt tactacttat
     6181 cagaaaggta gataggaaat cctgatgaag agtgtgtcca agggattatc aattaggtct
     6241 tagattacaa aatagtaatt caggtatgct ctactgtttt caacactagt tctgcaattt
     6301 gttttcgagc ttgcttagct tctcttattg gaaaaataac atacgcatga atcatttttt
     6361 ctgcaataat cagctgatta gcaattcgtt gtcttgttaa ttgatcatgt aaagacataa
     6421 tgtctgggta aaaaatctct tttgtcccaa caaaggtcgt tatttcaggc aaatcctcat
     6481 aatcaccata caaaggactg acataaggaa gttgcatatt accttgacca cctgcccata
     6541 gttcacctat atcacgaaga cgacgagcat ctaggtaagc ttcttctgct tcaaaatcct
     6601 tgtaggcttg atttttaaaa ctaacatcta accaaggaga tataagaatt aattgctttg
     6661 gctggggtgc tgttttagta tctcgtatat acttagcaaa cgccaaagcc atacccccac
     6721 cagaagaatc accaatgaca ctaacttgac tcggtccatt agacaagcaa aattgctggt
     6781 aagcttcaac taatttagga tagacatctt gataagtagc atacggtact ttaggaaagt
     6841 taggaaaaac aaccttggca ttagtcagct gtataagatg cttaaccgtc ttaaaatgaa
     6901 gtttttcggg tcgtcgtaaa tagacactgc cataaagata ataaataaca ggctgatgac
     6961 tttgcttttg atcattaata ataaaaactt gcatcccgtt cacatcgtat tcttgagttg
     7021 aaaaacctac tatctcttca ggattatcta gatgataagg gatattacga ttacgctgcg
     7081 tctcaacccc cttataatta tcaacttttt tagataactt atactttcta taagcaaaca
     7141 ttttctcaac caaccaactt gaaaaggagc gcttttgacc atattcaact atcaaaatac
     7201 ctagtatcac tccaaaaaaa atcaccacag caataatgac cacttattat cctcgttttc
     7261 taatattatt ttactattgc aagtctttcc tatttgccca aattttacta taaaaataag
     7321 ggttcatttt atagttgggc actggctgct tcgtttctag aaatggttgc actttcttat
     7381 caaaagctaa ccagccattc caaccgagat ggatggtatc ttgcataaag taggactcac
     7441 caccatcttt tgagaagtca gcaatgcgat gaaatccttg tgactttaac tggaatttta
     7501 ttttacgaac tgccgcttga tacttatctt gatttaagcc ggtataatcc gcccaagctt
     7561 tattaacagg agttataaca aagagtacat ctgtttttcg tttagcaaat tctgataata
     7621 aaagctgaaa atcattgtat tctggtgacg ccaggtaact ataattaact tggaaattct
     7681 tataaagatt gtatttaggt gctattcgtt tacgataaaa tgtattttta atcccaaaac
     7741 ggttgttggt tgttgctaat tggcctctct tagttgctaa tgcattcaat tgtttatacg
     7801 aaaatacttt aggtaatccc ttaacgcgag gcaaaattct tttttcatag ttagtagatt
     7861 tgcctaaaaa actaaaaagg gactcttctc tcaatgctac ttgatgttga catttcaaaa
     7921 tagctctgtc taaccgacta agagacttac ccttacttac ttttttcaat aagtttgatt
     7981 tagacacacc agggttaagc tcaagcaaac gctttgctgc aaactgtgat tctttatcag
     8041 ttctagcttt tagtaaaaat tcaatcactt gagtgttaga caagtacatc tgaaccgcac
     8101 taggattaat cccttgagca gtaaaccatt gaggagatac tacaaagatg gcttttttct
     8161 tttgcatttc attggtaatt tgttgcatac cataataatg cgacaaagat gctgatcctc
     8221 tcttaccaat taaaaatggt ctatagctcc gcttgtagcg ctctgcaagc accgaagggt
     8281 gcatactatc cattcgactc cattcgctag aaccaaaaaa aggcacaaaa cgacaagtct
     8341 catctgataa agcttgtctt ttaatcaaac catttttaaa agaactatct gtgatcgcaa
     8401 cggcatttgc tttttcctga gctatggaat gatcaagttg tgtaggaaaa ctaaaaatag
     8461 taatcactac taaaacaaag gcaataagaa gaggacctag aattaaccag agtctcttaa
     8521 gcatgttgca attcctctac accttgaaca atcttagtta ctgtgttcca atcatcacga
     8581 ccaaattctg aaataggtac tttaatattg aacgttgact ctaactcaac aatcaattcg
     8641 actgtcccaa gactatccaa cacacctgca tcaaacaagt cttcgtccat catctctgaa
     8701 acatcttcca taaacaaacg gtcaaacaat tcaattacag tttcttcaat agacattttt
     8761 atacttcctt ttattaatgt agtggtctgt taaaccaaag gtcatttaaa aaaccagaga
     8821 ataacagaag tgaaaacatg acaacgtgga aagttaccac gatacataag acatggaatg
     8881 ccctgctttg aaagaggggt gataagcctt ttttcttacg gtgacggttg atttcttttt
     8941 tcttacgaat ccaagcatca ttaataataa gtcctatacc atggaaaagc ccataagcga
     9001 tataatacca ggttaagcca tgccaaaatc ccatgactag catattaacc agataggcaa
     9061 cacctgaagt gacatttcgg tttttaaagg ttttatgctt aatcaataga tgaaccaatc
     9121 gcataaacac ataatctcta aaccagaagg acaaactcat gtgccatcta ttccaaaaat
     9181 ctttcaaact tgcagataag aaaggcatgt taaagttttc tggtgttcga atacccaata
     9241 ggtaggaaat accaatcgca aacatcgaat aaccagcaaa gtcaaaaaag agattcaagc
     9301 catacacgta cataaccaga atagtttcct tattaaagta gccaccaacc atcaaagcct
     9361 tattttcaag gagaggaagt aagatgccac ccaaacaata ggaaatgata tgcttgtata
     9421 gaaaacctaa catgagatac atgactgcct tattgagcat tgcaaaataa tcatcacgtt
     9481 caggaagttt atgataatct tcctgaaaac gtctgaagcg atcaatgggg ccacttgaga
     9541 aggtggggaa gaaaatcatg aagcgaataa aatccggtaa acgaacctct tggagagtcc
     9601 cgtcacgcat ctcaataatc attccaatac ttttaaaggt caaatatgaa atccctagaa
     9661 aactaaagag tgtttgagaa gaaggacctg ttaggggaac aactttgacc cagataaggg
     9721 ggaataaggc catcgcaata gctaagtaaa acactcctgc actattagct ttctcacggt
     9781 atttctggta agcaaaaaca ctgatgattt gccacaaaag ataaaagaga aaagcaacta
     9841 attgttgata atgatctcct ccaaacataa agagaataaa taccaaactc accaaggttt
     9901 cataagtgct taagcgcttt tgtttaaaaa tcccaatgat gactggtaag aaagccaaaa
     9961 taagatagac aaagtaaatg gggttaccgt aaggttccat gtagggaatg tggctaaaaa
    10021 acatcatcat cggttattga cctcattaat caaagtttta atatctatct taccatttgg
    10081 agttaatggt agactatctc gataaagaaa cttagaaggc atcatataac tcatcatatg
    10141 atccttaaca gaggctttga tagctttggt taactccaat tccctatcaa aacgctcttt
    10201 aaccccatct ttgacaacga tataggccaa gagattttga accttatgtt ctttattgta
    10261 ccttggaaca gccacagccg atgctaccat tggtgattga ttcaactgtt gggaaacatc
    10321 ttctagttca atacgataac cagcatattt aatctgaaaa tccaaacgcc caccatacag
    10381 caaaatatta tcttctgtca gtgagccaat gtcccctgta tgataagcag gctgtccttt
    10441 aaaagtaaag aaagcttctg cggttttctc aggattgttg aggtaacctt ttgacacagc
    10501 aggccctgta acaataattt caccctgctc ccctgaagct aactccttac catcttcatc
    10561 aataatatag gtcggagaat ctggtttggg gtagccaatc ggcaagcggg tataattatc
    10621 caccatttct ctggtaattt caatagcgga taaggctaca gtcgcttctg ttggtccata
    10681 ggcattgatg atcttggcac tcgggaaacg ttcaaagagt tttcgagccg tagaaacggt
    10741 taattcttcg ccatcaaaat aaaaatgcgt taaagctggc atcttagcct ggcaaaaatc
    10801 atcgctaagc atggccatat cagcaaatga aggagtcgat gtccaaatgc caactggaag
    10861 ttgcgcaatc gttgtaaata actgtttaaa gtctgccacc aattcttttg gaagtgcaaa
    10921 taaggttcca cctaaagcca aggtaggtgc ccagtacatg acagaaaggt caaaggaata
    10981 gggtggctgc gccagcattt gtggctgttt aggtacatca aatgctgcat cttcgatcat
    11041 ccagttggta aagctcaaaa gattgtcatg tgaaatttgc accccttttg gttggcccgt
    11101 tgttccagag gtgaaaataa tgtaataatt atcatctcct ttaacagaat gtgttcgctc
    11161 atagggcatt tctgctaatt ttgctgactc aatctctgat agtgagacaa gggaaatccc
    11221 ttcaatagta agagggaatt cctcaatagc aatgattaaa ctgggctttg caatctcaat
    11281 aatcgctaaa atacgttctg gtgctgaatg cacatctact gggatatagg catgaccaga
    11341 tttggttaaa gctacaaaag tagctaacat atcataagtt tgcgccccaa aaaccaaaac
    11401 tggagatttt gccagtaaag ctaagctatc tataaatgca gcaatgctat cagaatctct
    11461 tttgagttgt ccgtaagtgc ggcgttcccc taaacaatca taaactggga aatcagcctg
    11521 tgtctgagca aactgctcaa tactgtcaat catatcctta atcatcagtc aatctcctaa
    11581 aattcattat aaataaagtt actttgacca tgtcctagat aaccaaagaa atagaccagc
    11641 aacattaaaa tcagataaaa taaaattgtc ttgccaataa aaacagcaat tcctctcatt
    11701 cttgatttgt tttttatcat actttacctt cttgtattag tgaaataatg tcctaaaaaa
    11761 ttctactcga aaaaacctaa cttgacaagc taaaagtcat attattaaaa agaaaatttt
    11821 tttaaagctt aactatttag acagttaaat tttatgcctt tttactaaac ttactaagtt
    11881 aatctttact ttaaaaagtt aacttaaaat tgtcctaata aaaagaatta tttgacttta
    11941 acttatatat gttaataagt ataatataag ctttattcaa aacctagtcc attaatttaa
    12001 gttctaaaat caagtctcgc atttgagctg ccaattcgaa atcaagtaat tcagctgcct
    12061 cttgcatttg tttttgcaga gcattgatcg cttcttttcg ttctcctctt gacatacttt
    12121 cataatccat ctcttctttt gatatatcat tgtggcttgt tttacttata ctaataaggc
    12181 ctctgatgtc tttttttata gtttgtggaa cgatgccgtg cgctttgtta tatgctattt
    12241 gaatctcacg acgacgagcc gtttcgtcaa tagcccgctg catagaatct gtcatcttgt
    12301 ccgcatacat aatgacatga ccatctacgt ttcgagctgc tctaccgatg gtctgaatca
    12361 agccgcgttc attacggagg aaaccctctt tatcagcatc caaaatggct acaagactaa
    12421 cttctggcac atcaatccct tcacggagca gattgattcc aatcaagaca tcaaaaacac
    12481 caagtcgtaa atcacgaata atttctgtcc gctctaaggt tttaatatca ctgtgcatat
    12541 acttgacctt gacacccatc tcttttagat aatcagtcaa atcttctgcc atttttttag
    12601 ttaaggttgt gatgaacgtc cgttcatcgc gcgctacgcg ctggttaatt tctcccaaca
    12661 aatcatccat ttgccccata cttggcctta catcaatttc aggatcaagt agcccagtcg
    12721 gacgaataat ttgctcaata attgtattag tctgtgacat ttcgtattca ccaggcgttg
    12781 ctgaaacata gacaatttgg tgcacatgac tttcaaattc ctcgcgtctt aagggacgat
    12841 tatcaagagc tgatggcaat cgaaaaccat agtcaactag catttgtttt ctggcttggt
    12901 caccattata catgcctttg atttgtccca ttgtcatgtg actttcatca atcataatta
    12961 aaaaatcttc tgggaagaaa tctaacaagg tataaggagg ttctcctggt gacctgccat
    13021 ccatatgacg ggaatagttt tcgactccgc tagtatagcc catttcacgt aacatttcaa
    13081 tatcatattc cgttctttgg cgtaatcgct gtgcttctag tagtttacct tcagattcaa
    13141 ataactgtaa ctgctctgct aactctgctt gaattttggc tattgattgc tccatatgct
    13201 catcatttgt tacaaagtga gtagctggaa ataaaaccaa atggtcaact tctccaatag
    13261 ttttcccagt taaactttcg atttcacata tacgatcaat ctcatccccg aaaaattcca
    13321 cccgaaaagc atgttcatcc ctggatgctg gaaagacctc aacaacatcg ccacgtacac
    13381 gaaaacagcc gcgttgaaaa tcaatatcat tacgctcaaa ttgaatatct actaattgat
    13441 ttagcaaagt gtcacgtgat atctcctgac ctggacgtag gctgactgct gaatctgcgt
    13501 actcttttgg cgaacctagt ccataaatac aagatacaga agctaccact atgacatcgt
    13561 tacgctcaag taaagaagag gtggctgaat ggcgaagttt atcgatttca tcattgactg
    13621 aactatcttt ttcgatatag gtgtcgcttg atgggacata tgcttcaggt tggtagtaat
    13681 cataatagga aacaaagtat tccacagcat tgtctggaaa aaattcttta aattcaccat
    13741 ataattgtcc tgctaaggtt ttattgtgag ctatcactaa ggtaggttta tttactttac
    13801 taattacttg gctcatggtg tatgtttttc ccgttcctgt agcacctagg agaatctgag
    13861 ctttttctcc gccctcgata ttatcaacta ggctttcaat agcttgtggc tgatcaccag
    13921 acggtttata ctttgatttt agtttaaatg gtttatcatc acgtttatca atcattttat
    13981 accctctaat agtcttactc tcttatagac tattttaaca tagataagcc agaatcacct
    14041 ccaataagcg taaaaaacat gtcatttaca tgttatgttt tatgacatat aaataacaaa
    14101 tttcttgctt aatgttcaat attttgttat aattaaccat attttttagt tttataagga
    14161 gattagtatg acgcacaaaa taaaagtatt gctgcttgcg ataatgtcta tttttttgac
    14221 atgcaatatt gcaagtgctg aaactattgc tattgtttca gatacagctt atgccccatt
    14281 tgaatttaaa gactcagatc aaatttacaa aggaattgac gttgatatta ttaatgaagt
    14341 agccaaacgt caatcttggg atttcagtat gagtttcccg ggttttgatg cagctgtaaa
    14401 tgctgttcaa tctggtcaag cgagtgctct aatggccggt acaaccatta cgaatgctcg
    14461 taagaaagtc tttcatttct cagagccata ttacgatacc aaaattgtca ttgcgacacg
    14521 taaagccaat gccatcaaaa aatacagtga cttaaaagga aaaacggtcg gtgttaaaaa
    14581 tggaacagcg gctcaagcct ttttgaataa ctataaaaaa aagtatgatt atactgttaa
    14641 aacatttgac acaggtgatc ttatgtataa tagtttatct gctggttcta ttgccgctgt
    14701 tatggatgat gaggcggtta tccaatacgc aatcagccaa aaccaagata ttgctattaa
    14761 catgaaagga gagcccattg gaagctttgg gtttgctgtc aaaaagggaa gcggatatga
    14821 ttatctagtt aatgatttca atacagctct taaagctatg aaagctgatg gtacctacca
    14881 agctatcatg accaagtggt taggcacaga tgataaagct accaccagtc aggcaacggg
    14941 aaatccatct gccaaagcta cacctataaa ggacagttat aaaattgtct ctgattcgtc
    15001 ttttgcacct tttgaatttc aaaatggtaa gggcaaatac gttggtattg acatagaatt
    15061 aatcaaagct attgctaaac aacaaggttt caaaattgaa atcgctaatc caggtttcga
    15121 tgctgcctta aatgctgtgc aatctagcca agcagatggg gtcattgctg gtgcaactat
    15181 tactgacgct cgtaaagcta tctttgattt ttctgatcct tattatactt ctaatatcat
    15241 tttagctgtt aaagctggaa aaaacatcaa gaactatgaa gacttagaca gaaaaacagt
    15301 cggtgctaaa aacggtactt catcttactc ttggttaaaa gaaaacgctc ctaaatatgg
    15361 ttataatgtc aaggcatttg atgatggttc tagcatgtat gatagcttaa attcaggttc
    15421 tgtagatgct atcatggatg atgaggcggt tcttaaatac gctatctctc aaggtcgtcg
    15481 ctttgaaaca cctcttgagg gcatttctac tggtgaagtt ggttttgctg tcaagaaagg
    15541 aactaatcca gaattaatcg aaatgttcaa caatggctta gctgctctca aaaaatctgg
    15601 tcagtatgat gacattatag ataaatacct tgactctaag aaagctgcaa ctccttctga
    15661 aaaaggtgct gatgagtcta ctatttcagg cctattatca aataactaca aacaactatt
    15721 ggcaggactt ggaaccacgc tcagtttaac ccttatttca tttgctattg ctataattat
    15781 cgggatcatc tttgggatga tggccgtgtc accaactaaa tcacttcgac tcatttcaac
    15841 ggtctttgtg gacgttgttc gagggattcc tttgatgatt gtggctgcct tcattttctg
    15901 gggagtacca aaccttatcg agagtatgac cggccaccag tcaccgatta atgatttctt
    15961 agctgctaca attgcactgt cacttaatgg cggagcctat attgctgaaa ttgttcgcgg
    16021 tggtatcgaa gctgttccag cagggcaaat ggaagctagt cgaagtcttg gtttgtctta
    16081 cggaaccacg atgagaaaag taattctccc acaagctgtg aaactaatgt tacctaactt
    16141 tatcaatcag tttgttattt cattgaagga tacaacaatc gtctcagcaa ttggtttagt
    16201 ggaactcttc caaacaggta aaatcattat tgctagaaat taccagtcgt tccgcatgta
    16261 tgctatttta gcaattattt accttatcat gattacactc ttaacaagac ttgcaaaacg
    16321 tttagaaaag aggcttaact aatgacagaa ttaaaaattg atgttcaaga tttacacaaa
    16381 tcttatggtc aaaatgaagt cttaaaagga attgatgcca aattctacga aggcgatgtc
    16441 gtttgtatca ttggtccttc tggttctggg aaatcaacct ttctacgtac cctcaacctc
    16501 ctagagacga ttaccagtgg taaggtcatg gtggacggtt ttgaattatc agatcctaag
    16561 actaatattg acaaggcacg tgaaaatatc gggatggtat tccaacactt caaccttttc
    16621 cctcacatga ctgttcttga gaatattatc tttgctcctg ttgaattagg taaagagtct
    16681 aaagaagttg ctaaaaagca tggcatggca cttctagaaa aagtcggact ttctgataag
    16741 gccgacgcct tcccaggaag tttatccggc gggcaaaaac agcgtgtcgc catcgccaga
    16801 agtttagcaa tgaacccaga tattatgctc tttgatgaac caacttctgc tcttgacccc
    16861 gaaatggttg gggacgtttt gaacgttatg aaagacttgg cagaacaagg catgaccatg
    16921 ttaattgtta ctcacgaaat gggatttgct cgccaagtag ctaaccgtgt tatctttaca
    16981 gacggtggtc aattcttgga agatggtact cctgaagaga tttttgatca tcctaagcac
    17041 cctcgtctca ttgaattttt agacaaggtc ttaaacgtct aatagagcag acaccatact
    17101 aacttccaaa aaataataag gcaaggaaac aggtttcctt gccttttttg gttactgtta
    17161 ttattcaaac cagcaaaata gggatactct tatgactctc tccttcataa gagtgtcccc
    17221 tatgcttttt tatgggcgtt tatgtttagt gaggtaataa cctaatcccg taagagctag
    17281 tcccgtcact atgtgtaagt atttgttacc aaccatcgga ctaatggcaa tgagaaaaaa
    17341 gccaacagcc attaaaaaag ttgctccatt tttttctgtc atgcaaggtc actcgctttt
    17401 tctttattgg ccaaaatgac aaatggtgcc cagataagga aggcaacaaa gaggttaaac
    17461 agtgaaacca aacctgccat aatattacct ccagtagcta ggtaagcata aagtccaaca
    17521 ggggtaatcc aaggtactga taagaatacc ggtggaatca aacctattgc agtagcaaaa
    17581 taagctatgc tagcacaaat tggtggcaca attagccatg gaatcacaaa ggttggattc
    17641 aaaacaattg gcatcccaaa tgtaattggt tcgttgatat tgaaaacacc cattggtgcg
    17701 gacaatttgg caatggtttt atgctcttct cgttttgaga atatgaagat agcaataatc
    17761 aatgccaagg ttactcctga accacccatt tgagcataag catcaaagga cccgcgtgtc
    17821 caaaggtatg gtaaattagc agcgctatgc gctgtattgt aagcagctgt attttctgtt
    17881 aaagctacca tataaatacc atccatcact ggggctaaga cattatgacc atgcaagccg
    17941 aagaaccaga gcagttgaac taagaaggtt aacaagataa ctgaaccaat accctgtgat
    18001 aagcctagca atggtaattg gatataggtt gaaatgacat cacttaggga agaacctgtt
    18061 aatgcgaaaa tgaggtaggc gaaaattgcc gaagcgtaaa tcgcaactgt tcctggaata
    18121 atggcagcaa aggctttatt aaccgcaggt ggtacattat ctggtaaggt aatggtaata
    18181 ttacgtttgg tcaaagccgc atacacaaaa cttgataaaa agccaataat taaagctgtg
    18241 aacaagcctg tggcaccgac atactttaga gctattgctc cccattgact agtttcaata
    18301 cttgaagctc cacccgcagt aacgactgaa agccccattt ctttcaaatt gctaattagg
    18361 ttagcagagg cattttcaag tggtgtcgaa atggttaaag tctgaggtag ggtggcaata
    18421 aatgagccaa aagaaatcaa tcctcctgcc aatggattaa tcttatgcat aacagctaaa
    18481 ttgtaaccga aagcaaaggc aaaaaagagc gccatgatac caattgtccc aaaataaaca
    18541 tagccattga tgtcgataac aggttgcata gcttttgcaa atcctgtcca tcccatattg
    18601 tttggaatat cgcgtaaaaa aacgttcaat aagacagcaa ctgaacctgc catggtaata
    18661 ggcatcattg aaataaagga atcacgaata gctactaaat gccgttgtga cccaattttt
    18721 cctgaaatct ccataaactt atcagaaaaa tgcgacataa atcttctcct ctttttattt
    18781 ttttaatgta acaaaggtaa ccttaaaagc agcggtgtct gcctaacaca attatctcaa
    18841 aatcatcctt gttaaacgtg atgcttagag ataaccggta atcggctctt atccaaatga
    18901 acccttctct ctcattcaag gtctgtgaat aatcttcaca aagacgatgg ttgctgcaac
    18961 tgtttagcat attggataag ggctgctaac tgagcttgag attggcgttc taggcttttt
    19021 ttgaacagtt tgccaacaat aaattgattt gctttttgaa aaatatctag aggatgatag
    19081 tcataagaat aggtaattct agtccgattc tcccccagag cctctaattg ataagccaat
    19141 tcctttatcc catgattgga actaaaacaa gcagtatata attgcggagc ttctagggcc
    19201 gtaataagca ccctcactgt acgttctttg tatttaccat aatgtttaac atagtttatc
    19261 cccgctttga tatcatctct tgacaactgt ctcaaggtat tttgtcgata atcttcttgg
    19321 agcgatatca gcatggcttc aaaacaatga tgaatggaaa catctccttc tgctgaaata
    19381 atcatgactc acctctttgt attgctgaca ttttgtcgta aacggtaacc aattccttgg
    19441 ctaaatcaat aaaggctaag gcagtcatca tgtgatcttg cccatgcacc atcaataaag
    19501 acaattcaac cgcatcacca gctgcttctt gggacagcaa atgtgtctgc gatttatggg
    19561 caatatttaa cgagtttgtc gcttcttgaa gtaagtgctg agcctcctca aactgcccat
    19621 ctcgtgctgc atgaatagcc tctacggcct tgcccttggc ttcgcctcca tacatgatta
    19681 agcccataat agcttctaag ttggatggtt ccgtcatgcc tactcctcca tcattgctag
    19741 ggctgtttca aggacttttt caccgttcat aagaccataa tcagccatgt taatggcatc
    19801 tactttaata tctggttcaa acttatcttt aaaatccttt agtaagaatt tgacttgtgg
    19861 acctaacaag agaacgtcaa tgctattagc agccacttcg ttgtcagctt cactcacagg
    19921 aactgcccaa atagaaactt caaggtcacg cgcttgggct gctttttgca tcttagtcac
    19981 caacatacta gttgacatac cggcattaca aactaacata atagatttca taaggtttct
    20041 ccttttaatc gttttaatca tgaataagtg gggtaaacac tgtcatgaat ttggaataat
    20101 ttggttcttc tagtaacgct tgctgaagct ccacctgatt gacaaaagat gccaaacctg
    20161 gtgatacata ttttaaccta tgattatgcc ctttagacgg ggataataga aagacaaaat
    20221 gaacagcttg atgcgccttg tcccactcaa gaggctctcg gcaaatagac actactacct
    20281 gttcagaata agtcatggga ttagcaggat gcggaaaggc aagcacttct ccatagatga
    20341 ctgggctgta attttccctc agtaccattt gatgatagaa gtcctctaca aacgtttctg
    20401 ttcccgcctc gtcaagacaa gcaatcatcc gtaaaagcaa gtcttccttt gagattttct
    20461 cgtctaaata aagaaaacga ttagggctaa aaacacctgt tagaagctgc tctgcttttg
    20521 ataaactcat ctgtgacggt aaactgacct ctttcttgat accttcttgt tctccaataa
    20581 attgtcgaat agtttcaata tcctgatttg acaaaaaaac actgacagta atcactggtg
    20641 ttaaaaacat cagattggca aggctgatag aggaaataat caaatcaacg gttttcagtc
    20701 gctcttcggt tatttcatag taactgataa catcgacaat acgcaaacgt ccttcaaatt
    20761 ccttttccaa ccgatttttc aacatcatgg cactaccata acctgtggca caaactacta
    20821 gaaccctcaa tttatgacgg tttgaataac gctcaatggc cgccattaaa tgcaaactaa
    20881 tataagccca ttcatcatct gagacatcat tcttttgaca tacaagcaaa tccgaaaagg
    20941 tctgcttggt aagggtaaat atttcaggat actggctttt aatttcctca gttaaaggat
    21001 tagtcagctg aatatggttt tcaagacgtg tgatcaaggg catcatgtgg gctaataaac
    21061 cttgaaataa attggtatct gtttctaaag tcatgcctgt caattgacta atcttggcaa
    21121 tacatgcttt taaatggtcc tgcaactttt catcggtatt atcatcttgc caatgcttac
    21181 caacagaatg tttgaccttt agatgcagtg caatataatt agcctcctct ttaggaaaac
    21241 gtatccccat cacttcttcc actcgataca aaatgcgcag agctacttga tactcatcag
    21301 actgacgaat agctattgga atggaaaaca gttctaatgg acaccccgat cgaatacgct
    21361 gaaccattaa ggcaatatgc aagactagat tatttatgac aaaatcagaa agtttcaact
    21421 tagcatcccg acattcatcc aagacaataa tcatgatttc tgcaaaatta ataccttcaa
    21481 gaaagatatt acctaccatg gtggacaagg tattatcaaa actagtaaca aaaaaatagt
    21541 ccatgataaa atgcctaata tcctcttctt tacctcttat ttgaatatgt tggtgagtta
    21601 tttcaagctc taactggtaa ggtattatgc gctccttaat gcctgctaaa acatgtttta
    21661 aagttgtccg actgatatac aattcttgac aaagctcttc aaaatcctga acggcatctt
    21721 caaaaaagaa tttatgaagc acataatctt ctcgatcaac cgattcttcc acttgagaca
    21781 catctgccaa acgtttttta gacgtcacac tttcttgcca aaagatgtca aatgccatag
    21841 aatggtcaat ttctaagcag taacctcgac cttgtttaga aatgatgtga gctccgtgtt
    21901 caggaaggct actgatcagt tctttgaggt atttcctaac cgtacggtca ctcataccaa
    21961 taacctcagc cagagttgca ctagagacaa actgctcttt gtgatggatt agaaatgtta
    22021 tgatagccag ttcttttttt gataacatta gtcctcctta ctactttaga aaacgctttc
    22081 taccctcttt tagtgtacca aatatttcct gaaaaaggtg accatcattt tccgcattga
    22141 ttgtgaaaag aatctatgat gggtcaatct ccaaacaaaa ttcctgccaa ggtcgcaaat
    22201 catctaacaa actaagatag tcctctctga cctcagcaac cacattagct tttgaactga
    22261 ccgtaaaatt tttcaaagca atttgcagtt ctcccttata tcgatgatag cggtcattgt
    22321 caataataat gctacctcgt ttgacctcct tagattggtc tcttggagca atcgattcct
    22381 gagcatagac tagacgtggc atggttgatc gaatcacata atcagataca tcgccacgat
    22441 aacaatgcgg atagccaatg atttgctcct caacttctgt caaatcgatg ataggcctaa
    22501 ccttgatcgt tgtgactggc cttgctaaag cctgagtaca tgctgccaat tcttcttccg
    22561 aaatgaattg gttagatatg aggatattat caatggttcc tatcgctttc attaattcta
    22621 cttgcaggcc aatgggcaag tgcctatggt cttccactgt cggcaagcct tctgccagta
    22681 gccaagggcc ttcagatgct gactgagcgg taataaaagc agccgtttca atatcatgct
    22741 catgataaaa acgtgacata tccttaaaat gttgccatga caaaccggta aattcatgtg
    22801 gataaaaatt atggcaacca ataatattgc tccgttctgc atctgtcgct agcaatgaca
    22861 tcaataattg tttatcagtg ctcatattaa gttcaatttt aagcccaaag ggatttcttg
    22921 ttaaagttac aatctctgct agagggagag cctcgtctaa gcgtaagccc gctaacccga
    22981 aggcatgagc tcgttcaata agctgatctg accaaccagc ttggctaata aagcttggac
    23041 taacgtcagc aatcactcga atgcctaatt gatttgcata agcaatgagc tctgcgtagc
    23101 aatgaaacat ctggtgatca gctggtgcca gctgtaagag actcataaac aagcgcttgg
    23161 ctccatagct atgacataag tcaatataag ctttactctt ggtaacatca taccgctcag
    23221 ggtatagaga aaatcctaaa tcaaccatat tgcctcctat ttatcaaaac catttgactc
    23281 gctcaacgcc ttaaaccagt aacctgattt ttttatggtt cgcttttgac tctctaaatc
    23341 caaagctacc aaaccatatc ggtttttata agcatttaac caagaccagc aatcaataaa
    23401 agtccacaag aggtagcctt tgcagttggc tccttctccc aaagccttat gaagctggat
    23461 aagatgatcc tctataaagg tgatgcggta gtcatcttgt atctggccat ctgctaaaaa
    23521 agcttcttca ccttcgacac ccataccatt ttccgtgact agccattcga tgttaccata
    23581 gtgttctttt aaattaaggg caatatcata aagtcctggt tcataaattt cccaaccccg
    23641 gtgaggattg acttttttac caggcatatc ataaggttca aaataaatat ctaagataag
    23701 ggggtccccc tcttgctgtg acttactagg tgcctgaacc cgcaaaggct gataataatt
    23761 aactcccaaa aaatcaacag tattgttttt gataatctct aattcatcag cactatattg
    23821 aggtaataaa tcagcttcct ctaaaatgga aactaactct gctgggtaaa cacccaaaac
    23881 tgatggatct aggaaggatt tggtttggaa aagctctgcg attctagcag ccttgacatc
    23941 ttcaggagca ttactccgag gataagcagg tgtcatgtta agcacaatac taatcttgtg
    24001 gtcgggatga agcttatgac aagctttgac tgccagtgaa ctggccagtt gtgtgttgta
    24061 agccacttga actgctgcct tggcatctac tttacaaggg tagtgataat aacctaaata
    24121 gccacattcg actggaacaa tcggttcatt aaaggtaatc caagtgttta ctaaatcacc
    24181 aaaaagctca aaacaggttt ttgcgtaggt ttcataagcc cagacagtag ctttgttttc
    24241 ccagccacct ttttcttgca aggcataggg gaggtcaaaa tgatagaggt taacaatcaa
    24301 tttaatacct tgagcaataa tgtcttgaaa tacttctcga taaaatgtca ccgcctttgg
    24361 attaacctcc ccgactcctt ctggaatcaa tcgagaccac tggattgagg tccgaaaaat
    24421 cgtgtggcct gtttctttca aaagggcaat gtcaccctta tagttttcat aaaaggttga
    24481 ggttttttct ggaccaattt ggtgatgaaa cttagctgac tcaatactaa accagtaatc
    24541 ccagttgcta ggtcctttgc catctccagg aaccgttcct tcgctttgag gcccagatgt
    24601 ggaacttccc cataaaaagc catctggaaa ttgataacgg tgttttcttt gtttcatatc
    24661 ctttgtcctt tctttgctca cttctctttt tattataaga agaaaaacag gtgatgtaaa
    24721 cgctttaaaa aatctgtttt ttccttatca tcacggaaaa taagtgattt aaagcttgac
    24781 atattttatt atcttaaaga gcctatctaa cctgccctgc tacttcttat caaaaccaag
    24841 cccctattga cagatgcctt agcctatgtt tgaatagggg tatggcttat ttaaactact
    24901 ttacaaaaac cgagtgggca ctttggttaa gctctgtctt ggccatttta attagcgccc
    24961 ttttattcgg taagcaagct cccttagctt taatagcttc tttgattggt gtgacctctc
    25021 tcatttttag tgctaaagct aatcctattg gtcaagggct cgtcattatt ttttccatta
    25081 tctatgccta tctttcatta cgaaacagtt actatggaga gttaatgacc tatcttttca
    25141 tgaccctccc tatgactatt ttttcacttt ttacttggtt aaaccatcct tttgaaggga
    25201 aaaaatcaca agtgactatt tcacgattaa cacccactga tcgaagatgt cttttcgttt
    25261 ttactatact ggtcactctt attttctacg gcatcttggc ttctattcaa acagcctatt
    25321 tacttgtctc cactttatcg attgccactt ctttctcagc cgtttatctc agttataagc
    25381 gtagccctta ttttgcttta gcatacgggc tcaatgatct agtcctcatt ctcttatgga
    25441 tgcatgctgc tcaaacagat tctagccaat atgcagtagt catctgcttt gccacctttc
    25501 ttattaatga tagttacact ttttatagtt ggctaatgct ccaacgttac caagaaaaaa
    25561 aggtcaaaaa aggatgaggg cctaagcctc atcctttttc aatttttcac gttctaagcg
    25621 caaacgtcta ttgggattta aaagattaaa caattcttct aatttctcag cattccaaac
    25681 atctgctgcc gatacaaaat ttccatcctt atccttaaag gatatcggtt tatcacccat
    25741 aatcagaaac ctccatctta aagataacac acaagagcac tatcacactg ctattgtaat
    25801 ggattgcctt aatccacaaa ttcaaattca aacttgccaa tacgaacagg atccccatct
    25861 tttgctccac gttcacgaag ggcttcgtca acccccatac cacgcaattg acgggcaaat
    25921 ttcatgatgg actcatcacg ttccatattg gtcatgacaa agagacgttc taacttctca
    25981 ccagacaaga cccaagtagc gtcatcgtca cgtgtgatct caaagtcttt ttcagtctca
    26041 gcaaagccat agtaagcttc ttcatccacc agatcagctt catcatataa taagaattcg
    26101 tctgttttag cgagtaattc tgccgttgct tctaacaagt tctctaagcc ttgatgtgct
    26161 aggcttgaaa tagggaaaat cattggcaaa tcattaaact cgtcatattg ggtagccaat
    26221 tttttcttga aggctttcaa gttttcttga gcctctggca tgtccatttt attagccaca
    26281 ataatctgtg ggcgctccat caatcgcaaa ttataggttt ccagctcgtt attaatggaa
    26341 acataatctt cgtaaggatc acgaccctca ctagcagaca tgtcaatcac atgaagaata
    26401 acccgtgtcc gctcgatatg acggaggaat tgagttccca aaccaacccc ttggctagca
    26461 ccttcaatca aacctggcag atctgccata gcaaagctat cacctgactt tgtacgaacc
    26521 attccaagat taggaacaat agtggtaaaa tgataggcac caattttcgg tttagctgat
    26581 gacacaacac ttaacaaggt tgatttccca acagatggga atccgaccaa gccaacgtca
    26641 gctaagattt tgagttctaa ctctaactga cgttcctcac ctggctcacc attttcagca
    26701 atctctggcg caggattacg aggagttgca aaacgaatat tcccacggcc accacgacca
    26761 cccttagcaa tgaccacttc ttgaccatgt tctactaagt ctgtaattac ttttccagtt
    26821 tcagcatcac gaaccgttgt cccttgagga acaaagacaa tcaaatcttc tgcaccacgg
    26881 ccgtgcatgc ctttggtcat acctttttca ccagatttcg ccttgaattt acgattatac
    26941 cggaaatcca tcaaggtacg caaaccttcg tccactcgga agataactga gccaccttta
    27001 ccaccgtctc ctccccaagg accgccattt gggacgtact tttcacgacg aaaagctacc
    27061 ataccatcgc caccacggcc tgcttggaca ctgatttttg ccgtatctaa aaacatactc
    27121 atactttttt tattctctaa ctttctttta ctttaaaaaa acgcctttca gcgtttcctt
    27181 acattaatac tgatagggca ctcgcaataa gcccgccaac agttacaaga accattagga
    27241 taacaacgac cattgtcact ttttcaaagg ttgttttttt gcgaggtcca ttttctccaa
    27301 atgccacgtt aaatacctca tctattgatt tttcttctta tatcttaaca tgaaagatcg
    27361 ttttaggcaa atatcagatg aatatttacg ctatgtaggc tattactgag tattgtatct
    27421 tgtgaatttc atatgaatat gatacattag catttgcaaa ataatgttac agataaaaac
    27481 ctcctcgtct ggtgaactgc accccaaaag ttagacacaa a
//
LOCUS       DAUCXI010000023        27476 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.023, whole genome shotgun sequence.
ACCESSION   DAUCXI010000023 DAUCXI010000000
VERSION     DAUCXI010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27476
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.023"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(38..607)
                     /locus_tag="VGY43_001053"
     CDS             complement(38..607)
                     /locus_tag="VGY43_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ4302244.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEIIISAIITFVLIPTLSRLKR"
     gene            complement(665..1210)
                     /gene="coaC"
                     /locus_tag="VGY43_001054"
     CDS             complement(665..1210)
                     /gene="coaC"
                     /locus_tag="VGY43_001054"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEQ4302245.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     LVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(1203..1895)
                     /gene="coaB"
                     /locus_tag="VGY43_001055"
     CDS             complement(1203..1895)
                     /gene="coaB"
                     /locus_tag="VGY43_001055"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEQ4302246.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKPLPNKRLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            2076..2927
                     /locus_tag="VGY43_001056"
     CDS             2076..2927
                     /locus_tag="VGY43_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEQ4302247.1"
                     /translation="MKGRIVITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKTEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKDFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            2924..4123
                     /locus_tag="VGY43_001057"
     CDS             2924..4123
                     /locus_tag="VGY43_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEQ4302248.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     VSYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVIKQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNVAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            4120..5118
                     /locus_tag="VGY43_001058"
     CDS             4120..5118
                     /locus_tag="VGY43_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEQ4302249.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEEAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            5160..5492
                     /locus_tag="VGY43_001059"
     CDS             5160..5492
                     /locus_tag="VGY43_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEQ4302250.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            5485..6297
                     /locus_tag="VGY43_001060"
     CDS             5485..6297
                     /locus_tag="VGY43_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HEQ4302251.1"
                     /translation="MPSSFDLLGEMIGLLQTEQLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAQIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKALYDTYLQKENNCE"
     gene            6290..7171
                     /locus_tag="VGY43_001061"
     CDS             6290..7171
                     /locus_tag="VGY43_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HEQ4302252.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGPRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILETKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            7218..8237
                     /locus_tag="VGY43_001062"
     CDS             7218..8237
                     /locus_tag="VGY43_001062"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEQ4302253.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KRTYQPAIEALHHLGATEVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLTEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     YLIFS"
     gene            8365..10035
                     /locus_tag="VGY43_001063"
     CDS             8365..10035
                     /locus_tag="VGY43_001063"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEQ4302254.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTPALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            10120..11697
                     /gene="cls"
                     /locus_tag="VGY43_001064"
     CDS             10120..11697
                     /gene="cls"
                     /locus_tag="VGY43_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEQ4302255.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGRWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMTSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLKQRP
                     WYQKLIGLLVRTIAPLL"
     gene            12037..12375
                     /locus_tag="VGY43_001065"
     CDS             12037..12375
                     /locus_tag="VGY43_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302256.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
     gene            complement(12846..14114)
                     /locus_tag="VGY43_001066"
     CDS             complement(12846..14114)
                     /locus_tag="VGY43_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEQ4302257.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYSTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPHFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTTDSYRNFTLDKSDRIIIT
                     GKKRYLSIAINQQIQSKLNSLIKNTCGKSN"
     gene            14204..15070
                     /locus_tag="VGY43_001067"
     CDS             14204..15070
                     /locus_tag="VGY43_001067"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEQ4302258.1"
                     /translation="MKRIVVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQSPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIEIMIKLTQKAELVLPNISEACLLTQTAYLAKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEDSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            15048..15605
                     /locus_tag="VGY43_001068"
     CDS             15048..15605
                     /locus_tag="VGY43_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ4302259.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRIPVGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVTIGQAKRGF"
     gene            15739..17283
                     /locus_tag="VGY43_001069"
     CDS             15739..17283
                     /locus_tag="VGY43_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEQ4302260.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGINRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKASILMVCHEPDFYNGWVTDTW
                     DFSKLT"
     gene            17648..18857
                     /locus_tag="VGY43_001070"
                     /pseudo
     CDS             17648..18857
                     /locus_tag="VGY43_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
     gene            complement(18913..20475)
                     /gene="guaA"
                     /locus_tag="VGY43_001071"
     CDS             complement(18913..20475)
                     /gene="guaA"
                     /locus_tag="VGY43_001071"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEQ4302261.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELHEINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEITK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     GKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            20642..22075
                     /locus_tag="VGY43_001072"
     CDS             20642..22075
                     /locus_tag="VGY43_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302262.1"
                     /translation="MLRKKRILGLFRPVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKKPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKRYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            22158..22856
                     /locus_tag="VGY43_001073"
     CDS             22158..22856
                     /locus_tag="VGY43_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ4302263.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            22945..23286
                     /locus_tag="VGY43_001074"
     CDS             22945..23286
                     /locus_tag="VGY43_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEQ4302264.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            23301..24863
                     /gene="ffh"
                     /locus_tag="VGY43_001075"
     CDS             23301..24863
                     /gene="ffh"
                     /locus_tag="VGY43_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEQ4302265.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNEELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENRNDYVLIDTAGRLQIDEKLMEELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQLFGKGFKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(24998..25696)
                     /locus_tag="VGY43_001076"
     CDS             complement(24998..25696)
                     /locus_tag="VGY43_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4302266.1"
                     /translation="MFSGHQLKTARLSRGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
     gene            26166..27236
                     /gene="xerS"
                     /locus_tag="VGY43_001077"
     CDS             26166..27236
                     /gene="xerS"
                     /locus_tag="VGY43_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEQ4302267.1"
                     /translation="MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIISLLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
BASE COUNT         8817 a         4632 c         5451 g         8576 t
ORIGIN      
        1 ttttaaaaga gaaaaactcg gttattgtga aagctaatta cctttttagt cttgatagtg
       61 ttggaataag tacaaaggta ataatagctg agatgattat ctcaacaata gcgtttgatg
      121 agatgatggc tgttagtagt gctttaatat ttccatcaaa aactgtcgcg aaaaaaataa
      181 atatcccaga taatacaaat atagtatttg ttagagaacc aatgataccg gatactatta
      241 aaccaaactg attaggaatc aatttatagc aataataagg ggtaatacca atcaaaatac
      301 gtgggataat agcaattatt aaagaagcga aagttccatg atcgacaaaa ggtgaaaaga
      361 gataatttgt aggcagtaga atgatggtat ttgtaatgac acttataatc cccattaatc
      421 ctcctaaaat agcacctatc cttgggccat ataagacaga agcaataata actgggatat
      481 ggacaagcgt tggtttgatt ggaataggcc aaatattaaa gacaagactg ctcacaaaat
      541 gaatgactaa catgatggca aaaaagatag caatacgaga aatatctgct gatttacggt
      601 gattcatttt actctccaaa aaatataata cttaattcta aaaaggtgat cagaaaaacg
      661 actgttaaag tttccaaatc gtatcaatag tagctaagat aacatcaata tcagccaaag
      721 caccaggtcc tttatctcca caggctaata agctagattt tggaggaatt tctgtaaacc
      781 ctattgtcga taagcgttta atattttctt gagtaatagg gttttgatac attttggtat
      841 tcatggctgg ggctattaat tttggtgtgg tagctggtag ggcaagagca acacttgtta
      901 caagattatc agcgaatcca tatgctagat gagcaatagt attagcagag gcaggtgcaa
      961 caataaataa atctgtgcgt tttgctaatt cgatatggtt gataactttt gggtcatgct
     1021 catccataac atctaaatga atagcatttt ttgataacac ttgcagggtt aatggtgtaa
     1081 taaattgtgt agcagcctga gtcattatga tgtgaacatc atagccaatt ttagttaatt
     1141 gactcgtaag atctgctgct ttataggcag atatactacc agaaacagct aaggtaatat
     1201 gtttagtcat gtttggtcat cctttcatat aataagtcag caattgcctc tttggtatct
     1261 gcagatgcaa cttcgttatt ggatatcaaa agagccttgt gcatacctgt ttggatatca
     1321 actaaatcat tggcgagaat ataatcagca tggtttttag ctagacttgc tctggctact
     1381 ttaattaact cttcttgagg cacattaact agaagtttga agccgactag tttaatatta
     1441 ggattccact gtttaacata agagataact ttgggtgttt ttttcaaaaa aagaacctga
     1501 taatcagatg cagatgagat tttcggctca ctgttatgtt cacatagaaa acaattaagg
     1561 ttatcagctt gagagacttg ttccaaatca gtcatgtaga ctggagtata gtcagaaaca
     1621 gccatactat gaattagaat gtcatggtga ggaacctgat ctttgagtgc agccattaag
     1681 tcgttaactg tttccacttc aataatcctt aggcgcttat ttggcagggg tttagtggct
     1741 gttttagtag tgactagggt aacgtcatga tgatattgta aaaatcgctc tgtgattaat
     1801 tttccaagtt gcccagttga gtgattagtg atacctcgta ctgcatctat aggttcagtt
     1861 gttccacctg atgttattat taatttcata gtcatatttt atcaaaaaag gagctgatag
     1921 taaacggaag ataatgacgc cagacattgt cttgcgtttg tattaatatg gaatagtaat
     1981 agatttctag taattaaaac gaagttctgg aaagcaagac actatagtag ctaaaatcta
     2041 aattttaagg taaaatagag caagcggttt caagtgtgaa aggaagaatt gtgataacta
     2101 ttagagattt agcgtcactg ccgatttttg tttacggtga tggaaataaa aaagttccag
     2161 gagctttgag tccttttgtg tggacagagg tgtttttaaa aactatcaat caagaaccta
     2221 atcaactgat cttacatatt tggccgatga caagaacagt tatattagga atgttagata
     2281 gacagcttcc ctactttgag ctggctaaaa cagagattgg caataatggt tatgttcctg
     2341 ttactcgtaa tattggcggt ttggctgttg tcgctgatga tgggattttg aatttttcgc
     2401 ttgttattcc agaccatttt tcggaatcta tcagtattag taatgcttat ttaataatgg
     2461 ttgatgtcat tagagagagt ttttcggatt attatcagcg tattgaatat cacgaaatta
     2521 aaaattctta ttgccctggt aattttgatc ttagtattgc aggccgcaag tttgcaggta
     2581 tcgcccagcg tcgtatcaaa aagggaattg ttgtgtctat ttacttgagc gtttgtgggg
     2641 atcaagcagc gcgtggtcaa ctcatcaagg atttttatga ggccggaaca caaggagaag
     2701 ttaccaaggt taattaccct caaattgatc cagaatgcat ggcaactctt tcagaactcc
     2761 ttgagacgcc ttttacagtg gcagaagtcc ttgaacgtct tcgattgacc ttgcgacagc
     2821 ttggcttttc cctcacggaa aaaagtccag atcaagcctt actgactaat tttgatgctg
     2881 tctatgaacg gatgcagcta gaagtcgtca gaaaggaagg taaatgaaag aaagatttag
     2941 tcctttattt gagcctttga ctttgccaaa tgggagtcaa ttggataatc gctttgtttt
     3001 gtctcctatg gtgaccaact catccacaaa agacggttat gtcacccaag atgatgtatc
     3061 ctatgctttg agacgagcag cttctgcccc tctacaaatt acaggagcgg cctatgtgga
     3121 tccttatggt caattgtttg aatatggttt tagtgttaca aaagatgccg atatttctgg
     3181 cttgaaagag ctagctcaag cgatgaaggc aaagggagct aaagctgtct tacaactgac
     3241 ccacgctggc cggtttgcta gccatgcctt gactaaatat ggctttgtct atgggcctag
     3301 ttacatgcag ttgagatctc cccaacctca tgaagtcaaa cctttaacag gtcagcaaat
     3361 agaggaattg attgcagctt acgctcaggc cactcggcgg gcaattcaag caggctttga
     3421 tggcgtggaa gtatcttcgg cgcagcgctt attgattcaa acgttctttt cgactttttc
     3481 gaacaagagg acagatagtt atggttgtca aacacttttt aatcgctcta agttaactct
     3541 agctgttttg caagctgttc aacaggtgat taaacaagaa gctcctgatg ggtttatttt
     3601 tggatttcgt gctacaccag aagaaactag gggaaatgat attggttata gtattgacga
     3661 gtttttgcag ttgatggatt gggtacttaa tgttgcaaaa cttgattatt tagcgatagc
     3721 aagttggggc cgtcatgtat ttcgaaatac tgttcgttct cctggccctt attatggaag
     3781 gcgagttaat caggtagtta gagattattt aagaaataag ctacctgtta tggctacagg
     3841 gggaatgaac acacctgaca aagctattga agcattagct catgctgatt ttattggagt
     3901 atctacacct tttgtcgtgg atccagaatt tgctcataaa atcaaagaag ggtgtgaaga
     3961 gagtattcat ttaaggattc gacctgctga tttgaaaagt ttagcgattc ctcaggcttc
     4021 tttcaaagat attgtacctt tgatggacta cggggaatca ttgcctaaag aatcaagaac
     4081 tttatttcgt agtcttactc acaattataa ggagattaaa tgaaagtcag tattcttgat
     4141 tatggggtga ttgataaaga aaaaacaccc caagaagctt tattagaaac gcgctgctta
     4201 gcacaagtag ccgacaaact tggttttcat cgtttttggg tagcagagca tcataatatt
     4261 tatgcctttg caataagcag tccagagctg ttgatgatgc atttagcaga tcataccaaa
     4321 cagattcgga taggttcagg aggtattatg cctctacatt atagtagctt taagattgca
     4381 gaatggataa tgactttaga ggccttgcac cctaatcgga ttgatttagg tattggcaac
     4441 tctttaggaa ctacgttagt tcaaagagct ctatcaagta tccattgcaa agacagctat
     4501 agtcaggttg tcacagaatt ataccagtat cttaatcctg atcatttgtc accactaccg
     4561 atttttgtta accctagggg taatacttac cctcagattt ggacgctaag caatagtttg
     4621 gagacagcag aactggctgg tcaattaggt ttaggctata cctttggtat tttcccctat
     4681 ataccaaaag atcctataac agaagctaaa agagtatcgg cacattatag aaaggctttt
     4741 aggccttcaa agctattaaa aatccccaag ttaatattag cagtttttat tgtcctttct
     4801 gataccgacg aggaagcaga agctttggct aaaccgttgg acatttggat gcttggtcag
     4861 caagatttta atgaatttaa gacctaccct gatgttgagg aggctagaaa ctatcactta
     4921 acagagaaac aaagagaagc cattgcagca aatcgtagtc gcatggttat tggatcacct
     4981 cacacagtca agaaacaatt ggataggctg atagaagctt gtcaagctga cgaattatta
     5041 gccatcccct tagttcctga atttgccaat agacaacgaa ccttagagct gctagcagac
     5101 ttatacgtga ccatttaacc ttaccaaaaa caattcccta aactgaaagg aaagaaacaa
     5161 tgaaaaaaat tgcaaattac ttattaattg agaaaacaga tgaccgctat accattagca
     5221 tgacaccaga attacaagac gatattggta ctattggtta cgctgaattt acggataacg
     5281 accaccttgc cgttgatgac attatcttaa atctagaggc ttctaagacc gtcatgtctg
     5341 tcttgtcacc attggctggg gcagttgttg agcgcaatga ggcagccaca ctaacaccaa
     5401 cccttttgaa ttcagaaaaa gctgaggaaa attggattgt tgtgctaaca gatgttgatc
     5461 aagcagcttt tgatgcctta gaagatgcct agttcatttg atttattagg ggaaatgatt
     5521 ggtctgttgc aaacagagca gcttactagt tcttgggcct gtcccttgcc taatgcttta
     5581 acaaagcgac aagacttgtg gcgggcgctc attaaccagc gccctgcttt gcccttatca
     5641 aaagattact tgaatctgga agatgcttat ctagatgatt ggcgtgcttc ttttgttcct
     5701 gtatcagtca aggattgcca aaaaactaat tataccagtc tttttcttta ccatggggat
     5761 attaggtacc ttgctgtgga tgctattgtc aatgctgcta atagtgagtt attgggatgt
     5821 tttattccta accatggctg tattgataat gcgattcata cgtttgccgg aagtcgttta
     5881 cgcttagctt gtcaggcaat catgactgaa caaggccgta aggaagccat tggacaagca
     5941 aagcttacca gtgcttatca tctaccagcc tcttatatta ttcataccgt agggccaaga
     6001 attaccaaag gacaccacgt ttctccgatt cgagctgatt tgttagcacg ttgttatcgt
     6061 tctagtcttg atttggcggt taaagcagga ttgactagcc tagctttttg ctctatttca
     6121 acaggagaat ttggctttcc taaaaaagaa gccgctcaga ttgctattaa gacagtttta
     6181 aaatggcaag cagaacatcc agaatctaag accttaacta tcatttttaa tacctttaca
     6241 tcagaagaca aggccttata cgacacttat ttgcaaaagg agaataactg tgagtaattg
     6301 gacaacctat cctcagaaaa acctcaccca ggcagaacaa ctggctcaat taatcaaaga
     6361 agcagatgcg cttgtagttg gtattggagc tggcatgtct gcagctgatg gttttactta
     6421 tatcgggccg cgttttgaga cggcattccc agattttatt gctaagtatc agtttttgga
     6481 tatgctgcaa gctagccttt ttgattttga agattggcaa gaatattggg cttttcaaag
     6541 tcgctttgtc gctttgaatt atcttgatca gcccgtaggc cagtcttatc ttgatttaaa
     6601 agagattttg gaaaccaaag actatcatat tattactact aatgctgata atgctttttg
     6661 ggtggctggt tatgatcctc ataacatttt tcacattcaa ggagaatatg gtttgtggca
     6721 atgtagccag cactgccatc agcaaactta taaggacgat acggtcatcc gtcaaatgat
     6781 cgcagagcaa aaaaacatga aagtcccagg tcaactgatt cctcattgcc ctgaatgtga
     6841 ggcgcctttt gaaatcaata agcgtaatga agaaaaagga atggttgaag atgctgactt
     6901 tcatgcccaa aaagcacgtt atgaggcttt tttatcagaa cataaagagg gtaaagtgct
     6961 ttatctagaa attggtgtgg gacatacgac gcctcagttt atcaaacacc ccttttggaa
     7021 acgtgtctca gaaaacccta atgccttatt cgttaccttg aatcacaaac attaccgcat
     7081 ccctctgtca ataaggcgac aaagcctaga actgacagaa cacattgcac aattgattag
     7141 cgccacaaaa accatttacc aaaaatcgta accaaagcca atagacggtt aattaagaga
     7201 tagagatgga gactaacatg taccttattg aaccgattcg taacggtaaa cgtatcaccg
     7261 atggagctgt tgctctagcc atgcaagttt atgttcaaga aaatctattt ttagatgatg
     7321 atattttatt tccctactat tgtgatccca aagttgaaat tggaaaattc cagaatgcag
     7381 ttgtagaaac taatcaagag tatttaaaag agcatcatat ccctgttgtt cgcagagata
     7441 ctggcggtgg tgccgtttat gtagattctg gtgctgttaa tatttgctac ttgattaatg
     7501 ataatggtat ttttggtgat tttaaaagaa cctatcagcc cgctattgaa gcccttcatc
     7561 atttgggagc aacagaggtt gaaatgtctg gacggaatga cttggttatt gatgggaaaa
     7621 aggtatctgg cgctgcgatg actattgcta atggccgtgt ttatggggga tattcccttt
     7681 tgctagatgt ggactttgaa gccatggaaa aagcattaaa acctaatcgc aaaaaaattg
     7741 aatcaaaagg catcaggtca gttcgtagtc gcgttggaaa catcagagaa catttggcac
     7801 cacaatacca aggtattacg attgaagagt tcaaagattt aatggtttgc caattgttac
     7861 agattgagac gattagccaa gctaagcgtt atgatttaac ggaaaaagac tggcaacaaa
     7921 ttgatgcttt aacagagcgt aaatatcaca attgggaatg gaattatggc aacgcgcctc
     7981 aataccgtta ccatagagat ggccgtttta ccggtggaac agtagatatt catttagata
     8041 ttaaaaaagg ctatattgca gcttgtcgca tttacggaga tttttttggc aaggcagaca
     8101 ttgcagaact tgaaggtcac ttgataggaa cacgaatgga aaaagaggat gtcttagcta
     8161 ccctcaatgc aattgattta gccccttatt taggtgcgat tacagcagaa gaattaggat
     8221 atttgatatt ttcttgataa aaaagatacc tcagaccggt aaagtgcgat taaaaacgaa
     8281 caataattgt tttaattcaa ataaatgtat gtatgatatg aattgtgata taatgacgtc
     8341 attacgtaaa attgaggagt catcatgaaa tcagatatcg aaattgccca aagtgtcgcc
     8401 ttacaaccaa tcactgacat tgttaaaaag gttggaatag acggcgatga cattgagctt
     8461 tatggcaaat ataaggctaa attgtctttt gagaaaatga aagctgtcga agctaatgag
     8521 cctggaaaat taatcttggt aactgctatt aaccctactc cagcaggaga aggaaaatca
     8581 accatgtcta ttggactggc agatgcctta aatcaaatgg gaaaaaaaac catgcttgcc
     8641 ttacgtgaac cctcccttgg tcctgttatg gggattaaag gcggggcagc aggtggtggt
     8701 tatgcccaag tattgcctat ggaagacatt aatcttcact ttactggtga catgcatgcc
     8761 attacaaccg ctaataatgc attatctgct ttgattgaca atcatttgca gcaaggaaac
     8821 gatttaggaa ttgatcctcg ccgcattatt tggaagcgcg tgttggacct taatgatcgc
     8881 gctcttcgtc aggtaattgt tggcttgggt agtccagtga atggtgtgcc acgcgaagat
     8941 gggtttgata tcacagtagc ttctgaaatc atggcaattt tatgtttggc aactgactta
     9001 aaagatctaa agaaacgtct tgctgatatc gtcgtggctt atacctatga tcgtaagcct
     9061 gtctatgtgc gtgacttgaa ggttgaagga gcattgacat taattctaaa agatgctatc
     9121 aagccaaact tggtgcagac tatttatgga acaccagctc ttattcatgg ggggccattt
     9181 gctaatattg ctcatggttg taattctgtc cttgctacct caacagcttt gcgattagca
     9241 gattacactg ttaccgaagc aggattcggg gccgacctag gagctgaaaa attcctaaat
     9301 atcaaagtac ctaatcttcc taaagcacca gatgctattg tcattgttgc aaccttgcgc
     9361 gcccttaaaa tgcatggagg tgtcgccaaa tcagatttag ccgctgaaaa ttgtgaggct
     9421 gttcgcttag gatttgccaa cttaaaacgt cacgtggaaa acatgcgcca attcaaagtt
     9481 ccagttgtgg tggctatcaa tgaatttgta gcagataccg aggctgaaat tgctacctta
     9541 aaagcgcttt gtgaagagat taaggttcca gtagaattag ccagtgtttg ggcaaatgga
     9601 gctgagggag gcttagcatt agctaaaaca gtggttcgtg tgattgatca agaagctgct
     9661 gactacaaac gtctctattc agatgaggat actttggaag aaaaagtgat caatatcgtt
     9721 acccagattt atggtggcaa agctgttcaa tttggcccca aggccaaaac acaattgaag
     9781 cagttcgcag aattcggttg ggataaattg cctgtttgta tggctaagac ccaatacagt
     9841 ttttcagata acccatcctt gcttggagcg ccaaccgatt ttgacattac cattcgtgaa
     9901 tttgttccta aaacaggagc aggttttatt gttggtttaa caggtgatgt gatgaccatg
     9961 cctggtttgc ctaaagttcc agctgccatg gcaatggacg tagcagaaaa tggcacagcc
    10021 ctcggtctct tttaggaaaa attgctcgaa taattcgagc aagcgctcct ttcttcccgc
    10081 tttactgtga tataataagg taaatgagat tttggaggga tgattatcaa aaagaaagca
    10141 aaagtaaaat atttgctcca taaagggaaa catggatttt taagaggaat ttttagtaga
    10201 acaacaatca ttgtattatt aattattttg caattagttt tcttatttca atcttatgcc
    10261 tggatggagc agtaccgtgt ttggataacg attcttgaaa gtgtctttgc tattactatt
    10321 gttttatatt tagttaatag tgatatggat gctatttcaa gaatgacgtg gttaattttg
    10381 attatgattg ctccattact agggtcactg tttttaattt atacaaaatt ggattggggt
    10441 tacagagggc taaaacagag aataaatcat cttgtagatc tgtctgcacc ttaccttagc
    10501 gatgatgacg ctatattaga ggtattaaag gatagcacat caaccacata tcatttagta
    10561 cagtacttag aaagaagtcg tggcaacttt ccgatttata ataatacaag ggtaacttac
    10621 ttcccaacag gtgaaacttt ttttgatagt ttaaaagaac agttattctt agctaaaaag
    10681 tacatttttc ttgaattttt tattattgca gaaggccaaa tgtggggaga aatccttagt
    10741 attctagaaa aaaaagtcag tgaaggtgta gaagttaggg tgttgtttga tggcatgaac
    10801 gaactatcaa cgctatcatc agattacgcc aagagattag aacaaatagg gattaaagct
    10861 aaatcatttt taccgatttc accctttatc tctacctatt acaattatcg agatcaccga
    10921 aaaattgtcg ttattgatgg ggaggtatca ttcactggag gtattaatct agcagatgag
    10981 tacattaatg aagtagagcg ttttggccgc tggaaagatg ctggtttaat gcttgagggt
    11041 gaagcaacag acagcttttt aattttgttt ttacaaatgt ggtctatcac agaaaaagaa
    11101 ctgattattg atccttatct ttcagatcat tctttaaaac ttccttcaga tggctatgtt
    11161 attccctacg gtgattcccc gcttgatact gataaaatag gtaaaaatgt ttatatagac
    11221 attttaaatc atgctaaaga gtacgtttat atcatgacac cttaccttat tttagatagc
    11281 gagatggaac acgctttacg atttgcatca gaacgtggag tagatatccg aattattatg
    11341 ccaggagtgc cagataaggg ggtaccatat gccttagcta aaacctatta taaagctttg
    11401 atgacttctg gagtaaaaat ttatgagtat caaccagggt tcgttcattc aaaggtattt
    11461 atctctgata atacaaaagc agttgtcgga acaattaact tagactatcg tagcctttat
    11521 catcattttg aatgcgcgac ttatttatat cgtgtgtcag ttattgctga tattgtgaat
    11581 gactttaatg aagctcaaaa gcaatcacta ttgatgacat cagatcattt gaagcaacgt
    11641 ccttggtatc aaaaattgat aggattatta gtacgaacaa ttgcccctct cttgtaattt
    11701 tcgtaaaata tgttataata tctgtatgcg atgagtcgat tgtgactgca aagtcacttt
    11761 tgcgcagggg aggtcattaa ggcgggaagc cgactttgat aatctgtgtg aaccatttta
    11821 tcacaatctt atttattaag aatgcccctt ggattgagat attctcaatc ctttttttaa
    11881 ttttattaac ttagttaaaa ttcagaatgt atcagtgatt actgtgtttc aaaataagaa
    11941 agtagttttt cgggtatgag tgctatgact tgacaaatgc taataacatt tgcataatgt
    12001 aagtagagat gaaaacttat gaaaagagat gatcttatgc aaattattaa gcgtgatggc
    12061 cacgttgctg attttgatcc agataaaatt tatcaagcaa ttattaaagc agcaaggacg
    12121 gtctatgtta ttgatgacac gtggcgacaa aacttaacac atgtcactaa aaaagtagtt
    12181 attgatttag aagaagcaca tgtagaacgt cctactatca atatggtcca atcccttgtg
    12241 gagaatcgtt tgatggatgc tggatatatt accattgcag aacattacat ttcttatcgt
    12301 cttcagcgag atttagagcg caatggctat ggtgataaga ttgtggttca cttgcgtttt
    12361 gaacaaataa aataaaaacg cttctaatgg cattttagtg tctttgaggg gataaggttt
    12421 aaatacctaa cagataaaaa tctgttaggt atttttttgc tactattagg tgtattctat
    12481 attacataga acttaagcat tcaagcctta gtttaacttt ctgtttattt tttgctacat
    12541 tttgggaaac tcccctcctt tcttagttga ggtgaataaa cttttatttg ataaatcata
    12601 tccttagtct taatgaaaca gtctaagata atactacttc gaagtgacag ctagtagttt
    12661 ccaattttta agtagtctaa aattatgttt ttttaatttc aaaaccatgc tttcgtttgt
    12721 tataaaaacc gatcttccat agttagagtt tttatccagg cattgaagat tggggcaact
    12781 atccaattag agattttata atacttattt atccccattt tttatattaa tggtacgaag
    12841 aaaagttagt tgctctttcc acaagtattt ttgattagcg agtttaattt gctttgtatt
    12901 tgttgattga tagcaataga gagatagcgt ttttttccag ttattattat tctatcagat
    12961 ttatctaatg taaagtttct ataagagtct gttgtcgtgt aatcaatcac taaatgagta
    13021 ggggttagtt gatagtgaat atcagggcaa ttttgtttta aaaagagagc caattgacgt
    13081 tcccgctgtt ttagataacg cttaataaag cgaagatttt tttgaaacat cccattttct
    13141 aaataaagag ctaatgcttt ttgcattagt aagttcgtgt ctaaatcaat caatgatttt
    13201 tgggttaaaa aatgaggttt taaacctgac ggtaaaacta gagctccgat acggagtgca
    13261 ggaaaaacac tcattgaaaa agattttaga tagatgattc ggtgatgagt gtcataataa
    13321 tgaattggtg gctctttaag tttcacaaaa tctcctaaat aatcatcttc taaaatataa
    13381 acctggtatc gttgtgctag acgaacaata gcttcctttt ccttagtgct ataagaaagt
    13441 cccagaggat gtgaaaatcg tgaaatcgtg taaaaaaatt taatatcgcc agtttgaaat
    13501 aaagattcta agagttctaa atcaaggcca ttaaagtgtc tagagatagt ttgatagggt
    13561 aatcctaact gagcaacaat agcttccatc cgatgataag taggcttttc aaggagaatt
    13621 gttttgcccg cattaggaaa aggcatttgt gataaaatat aaagcgcttg ttgcgtccca
    13681 gaggtgatta atagttggtc tttgttactg taaacactat tttcagctaa gtaaagaagc
    13741 aaagcttccc ttagttcttc tagtccttcg gttttgtgat aataatgaaa gaggtatttg
    13801 tctttagcac ttaaagcctc atttaagcag agtcggaaat cttcataagc catattatta
    13861 taatcttcaa gacttagatt aagaacatta tcgggcatgc ttacgttacc caaaacataa
    13921 taaccacttt taggaacagc ataaattaag tgacgatatt ttaattctaa aagagcccgc
    13981 tgaacagtat ctttgctaca atgataaacc ttacttaata ccctaattga aggtagcttg
    14041 tccccttttt ttagtcgctg tttctggata tcttgttcga tattggaaat gattgtttga
    14101 tattttgttg tcataaattg tccccataca gttaagtgtt ataactattg tatcttatgc
    14161 ccctttttct tacaatagtt attatagaaa agaggtaata gctatgaaac ggattgttgt
    14221 ggcaaatgat ctggttggtg ttggtaaggt agccttgtct gctagtattc ctttaatggc
    14281 ttcttgtttg ttagagcaag ttttattacc aacttgcctt ttatcaagcc atactggcgg
    14341 aggacagagc cctgtgaagc atactacatc aagtatatta gacgtttttt taacagattg
    14401 ggacaacaaa agaattaagt ttgacggcat ctttataggt tattttacga caacaagaga
    14461 tgggcaaaag ctgctagaat ggctttcaag aaagcaactt cccttaattt tagatccaat
    14521 tatggcagat aatggaaaac tttatcaagg cttcagtcaa aaacatatag agattatgat
    14581 aaaacttact caaaaagctg agcttgtttt acctaatatt agtgaggctt gtctattaac
    14641 acaaacagct tatttagcaa aaaattatga tgaagaagat attagacagg tggctagaaa
    14701 attagctaag cttggaccta aacaggttgt cattagcgga atctcttttg aggaggacag
    14761 cattggtttt gcttactatc agtcagattc agatcaatta acattccatt ttgggaagca
    14821 attcccttac catttctatg gtacaggaga tatagcatca gctattataa cagcaggatt
    14881 ctattatcag ctaccactaa cacaaattct agatcttgtt gtttcatttc ttgaaaaagt
    14941 attgcaaaat acccttacat taaaaagaga tttaatctta ggtgttgctt atgaatctca
    15001 tttaaattac ttaactaaat cgtttaaaaa gttgttggag gaaaaaaatg tcatctcaaa
    15061 aattagctaa ttatattgaa ttgagtatgt atgccgcttt aatttttatt tcagtacaag
    15121 tgttgcgtat ccctgtcggt atgcagttta ttcatcttgg caatgcatta gttgttattg
    15181 cagtcttaat ctatggtagt aaaaaaggag ctctagttgc tagtcttggt ttagggatct
    15241 ttgatgtttt gaacggctat gcttcagtcg tttggataac tatcttagaa tccttggcta
    15301 tttgtttaat tttgcatttg gtatatgaaa gagctatgca atctagtaaa aaaccaaaag
    15361 ccattataac aataacagtt attgctgcat tgtcaaaatt aactattaac cttataaaat
    15421 acttactgtt agcttatata ggtactcagc taccactttc agtatctttt tgggtagctc
    15481 ttggaaaaat tggtggtagt ttcggaacat cttttgtgac tttagttgct gttcctcttt
    15541 tgtatcctgt tatcaaaaac ttaaaagaaa aggttacaat cggacaagca aaaagaggtt
    15601 tttgatacaa gtaccttatc gataaaaaag caaggtacac ttttagtcaa atattgacaa
    15661 aaggttacaa ttttgccata atgaaataac tataaagccg ttttgacggc ttttttgatg
    15721 acagttaagg aagaaacgat gagtatttta gaagttaagc agttgagtca cggttttggg
    15781 gatcgggcta tttttgaaaa tgtgtcattt cgcctcttaa aaggcgaaca tattggacta
    15841 gttggggcaa atggtgaagg aaaatcaacc tttatgagta tagtcacagg acatttacag
    15901 cctgatgaag gaaaagtaga gtggtcgaag tatgtcactg caggttacct ggatcaacat
    15961 acagtgttgg aatcaggaca aaccgttcgt gatgtcttgc gaactgcttt tgatgagtta
    16021 tttaagaccg agaatcgtat taatgagatt tacgcgtcaa tggcagatga taaagctgat
    16081 attgctgttt tgatggaaga agtaggtgag cttcaagatc gtttagaaag tcgtgatttc
    16141 tatactttgg atgctaagat tgatgaagta gcgcgtgcgc ttggtgttat ggattttgga
    16201 atggagtcag atgttacatc cttatcaggt gggcaacgaa caaaggtttt attagccaaa
    16261 ttactattag aaaaacctga tattctgcta ttagatgaac caactaacca tttggatgct
    16321 gagcatattg aatggttaaa acgctattta cagcattatg aaaatgcttt tgtgttgatt
    16381 tcgcatgata tttctttctt aaatgatgtg attaatattg tttaccatgt tgaaaatcaa
    16441 agtttagttc gctatactgg ggattattac caatttcaag ctgtttatga gatgaaacaa
    16501 tctcaacttg aagcagccta tgaacgtcaa caaaaagaga ttgctaactt gcaggatttt
    16561 gtcaaccgaa ataaggctcg ggtagcgaca cgtaacatgg caatgtctcg ccaaaaaaaa
    16621 cttgataaga tggatataat tgaacttcaa gctgagaaac caaaaccaaa ttttgaattt
    16681 aagcaagcta gaactcccag tcgattcatt tttcaaacaa aaaatcttgt gattggttat
    16741 gattacccat tgaccaaaga acccttaaat ataacgtttg aaagaaacca aaaaattgct
    16801 attgttgggg ccaacggtat tggaaaatct actttgctaa aaagtttatt aggtgttatc
    16861 gagcctttag aaggtcatat tgtcacaggg gattttttag aagttggcta ctttgaacaa
    16921 gaagtgacag gtattaaccg acaaactccg ctagaagtag tttgggatgc ttttcctgcc
    16981 ttaaatcagg cagaagttcg agcggcacta gctcgttgcg gactaacatc aaaacatatc
    17041 gaaagtcaaa ttcaagtact ttcgggtggt gaacaagcaa aagttcgttt ttgtttgttg
    17101 atgaatcgtg aaaataacgt gcttatttta gacgaaccaa caaatcatct tgatattgat
    17161 gctaaaaatg agctcaaacg tgctttaaaa gcatataagg cttctatttt aatggtttgt
    17221 catgaacctg atttctacaa tgggtgggta accgatactt gggattttag taagttaacc
    17281 taaactattc cttaattttt tacacagaaa ttactaaaat cagtaaagat atagaataaa
    17341 tactgctaga tatgtgatgg tttaggtaac tgatcaccaa ccaaaaaaga tgtgactaca
    17401 tctttttttt atctaatgga atggtgtaaa gtcgtttaat aatagcttat tttttgatga
    17461 tcagttgttc atgaaattgt tggtgattaa caagtcattt aagatacaaa cgttattact
    17521 aaaaagtgat tcaaatagtt tccctatttt tatgtttttt taaaatttat tacgaataaa
    17581 tagataaaga cagtgaagat gattagtaag tacatctgct aagattacga atagatgggg
    17641 acaataaatg acgaatttaa cgttttatgc aaaaatcggt atttcagaag aagagcatga
    17701 ctcttttgtt aaagaacatc agcaaattag cgttttacaa ggtagtgatt gggcaaaaat
    17761 caaaaatcaa tggcagaatg agcgaattgg tatctataaa gaggaaaagc aggttgcctc
    17821 tttatcactt ttgattaagc tattgccact tggaagaagc attatttata ttccaagagg
    17881 gccagtcatg gattatcttg accgtgattt ggtggcattt accatgaaaa cactaaagga
    17941 ttatggtaaa actaaaaagg ccctctttat caaatatgat ccagctatcc tgttaaaaca
    18001 atacgcactg ggacaggaag aagaagaaaa acctttagct ttagcagcta ttaagaatct
    18061 ccaagaagct ggtgttcatt ggactggttt aacaatggag attgcagata gtatccaacc
    18121 tcgtttccaa gctaatattt acactcaaga aaaccttgag atgcaatttc ctaagcatac
    18181 cagacgttta ataaaagatg ctaagcagcg tggtgtagaa acatatcgtg ccagtcaatc
    18241 agaacttcac aaattttcca agattgtctc cttaacagaa aagcgtaaaa atatttcttt
    18301 gcgtaacgaa gcttattttc aaaagttgat gactacttat ggggataggg cctacttaca
    18361 tctagcaaaa gtgaatattc ctcaaaaact agatcaatac cgccagcaat taaatcttat
    18421 taaccaagat attactcgca cccaagctca tcaaaagaag cgtttaaaaa aattagaaga
    18481 tcaaaaagct tctttagaac gttatataac tgaatttgaa ggctttacag accaatatcc
    18541 tgaggaagtt gttgtagcag gtatattatc tatttcttat ggaaatgctt tatgctggga
    18601 tgaatgatga ttttaagaag ttttatcctc agtatctgct gtatcctaaa gtttttcagg
    18661 atgcttatca agatggtatt atttgggcta acatgggagg agtagaaggc tcgcttgatg
    18721 atggacttac caaatttaag gccaactttg ctccgacaat agaagaattt ataggagaat
    18781 ttaatctccc tgtcagccca ctttatcata ttgctaatac catgtacaaa atacgaaaac
    18841 agttgaatgg gaataacaga ataaacatta aaagactcgc caaaatgagc gagtctttta
    18901 atgtttattc tgttattccc attcaactgt tgcgggtggt ttacttgtga tgtcgtagac
    18961 gatacggtta acgtggtcaa cttcatttac gatacgtgtt gagatttttt tcaagacatc
    19021 ccaaggaagt tgagcaaagt cagctgtcat accatcaata gacgtaatag cacgaatggc
    19081 gatggtataa tcataagtac gaccatctcc catgacgcct acagaacgga cacctgtgtt
    19141 aactgtaaag tattgccaca cgtcacgatc aagtccagcc ttagcaattt cttcacgaag
    19201 gatagcgtct gattcgcgaa cggtttcaag tttttcttca gtaattgctc ccatgacacg
    19261 gatagcaagt ccaggacctg gaaatggttg gcgccaaaca atttcttcag gcattccaag
    19321 agcgattcca agcgctcgaa cttcatcttt gaaaagagtg tttaagggct caatcaattc
    19381 aaactgcatg tcttcgggga gaccacccac attgtgatgt gatttgatgg tttgagcagt
    19441 ttctgttcct gactcaatga tatcagtata aagtgttcct tgggcaagga agtcaacacc
    19501 ttttaatttg ctggcttcat catcaaaaac atagacaaat tcattaccaa taattttacg
    19561 ttttttctca ggatcttcaa cgtctgcaag aaggtctaag aaacgttttg aagcatccac
    19621 acggataata tttaggccaa atttgccccc aagcattccc ataacttgat cgccctcgtc
    19681 tttacgaaga agaccgtgat caacgaaaat acaagttaat tggtcaccga tagctttttg
    19741 aagtagaaca ccaacaactg aagaatcaac tccaccagaa agacctagaa gaactttacg
    19801 atcgcctaca gtttcacgaa ttttagtaat ttccatgtca ataaaattat ccattgacca
    19861 atcaccacgc gcgccacaaa ttgatatagc aaagttttta agaatgtcat tcccataaac
    19921 agagtgtctc acttctgggt ggaactgaat accgtaaagg tttttctcag tattttcaat
    19981 agctgcatag ggacagtcat ttgagtctcc aacaaggtgg aaaccttctg gaatttcagt
    20041 aacagcatca ccatggctca tcaaaacgag ttgttcttga ggtgtgcctg aaaataattt
    20101 tgacgtttca cgaagatgaa gggttgactg accgtattca cgattaccag cttgtccagc
    20161 aggaacaact ttaccaccta atttatgggt gattaattgc ataccgtaac agataccaag
    20221 aatcggaatc cctagttcaa agatttcagg gtcaatgcca aaggcgttat cagcgtaaac
    20281 agagttaggc cctcctgata aaacgatacc tatgggattg atctcatgaa gttcttgagc
    20341 ggtgatttta tggcttttta gttcggagaa aacaccaaac tctcgaatac gtctagcaat
    20401 aagctgattg tactggctac cataatcaag aacgataatt ttttgaacat cattcaaaat
    20461 tgaaatttca gtcattataa tcctttcatt ctataccaac cgtcaggctg atagttgtca
    20521 acttattgta gcatattttc atcgaaaaga cattacaatt tctctagctc gttggaaaaa
    20581 aacgtaatcg ttatgttaca atagaggcta tgaaagggaa ttaagacaac agggagggcc
    20641 tatgctaaga aaaaagagaa ttttgggttt atttcgacct gttgaattaa ttttcctagg
    20701 attattgttg agtttagttg tttcgtacct tgcgtggacc aatagttttg caacacttca
    20761 taatatatta gcaactgtcg gaatagtgga acgaagcaaa gatcaacagc ctcgctatca
    20821 cattggacaa gctattcaag tacaaaaaag tggtccatat catcaatgga ttggaactat
    20881 taataaacag gtagaagata tagccgaaaa ttaccgagtg agttatcatt atgaagtggt
    20941 atttccaata ggaaaagtca ctgtttcttt gccagaacat aacctgaaaa agcctgataa
    21001 accgaggttt aaaaaaggag atatcgttaa attatcttca ttaactaaaa agccacatat
    21061 aaaagtgtat caaggtcaat tagcgactat taaacaagtt aaaaaacgct atgactattc
    21121 gttaggagga tatcagtacg atattaacct gaaagataat ctaagattag atggaatttc
    21181 agagcaagat tttgttaaac cttattatat taggttcaat aaaggaaatt cccctgagca
    21241 aaacaatcgt cttttgcgaa aagctttcgc ctatgcaaag cagcatccaa atagcgttat
    21301 atcttttcca aaggggcaat ttcacattgg ctctttgcct tcacaaaaag attattttga
    21361 gcttccatct gatacagcta ttattggtca tcagacagag ttcattattc acggtaaaat
    21421 gttgtggttt ggattcccta caggaccaaa ggctgaacaa ggtgttcgta atctcgtgtt
    21481 gactggagtg catttcaaag caaatgattt gaaaaaagga gaccacttta tgattatggc
    21541 tgatcatggt actgattggc atatttacga taacaaattt actatggttc ataagcgtaa
    21601 tagtcatatt tttgatttag gatctctaca aaattcattg tttgagaaaa accaatttat
    21661 tggctatgcg ccagaattag tacaagacca acagctgcta tcaaaggctc aagggcatga
    21721 ttttttttca gaagtcattc agtttgatgc tgctgttcat cattttgcat gggatggagg
    21781 tctacttagt aatattgctc caaactatga agcatttaac caaactcgac atctatgtca
    21841 caatattact gtaagccaaa atcaattttt accttatata gatccgactg gttgcctgag
    21901 agcctatagt ggttctattg gtcagcattc ctcaaaagta ggagttatta gggttttaaa
    21961 taatgttttt acctcatcca ttgttactaa agcgaagctc actagttggt ttatggaacc
    22021 tattcatttt ccaccaaatt caccagttat tgtcgcaggt aatatcatta attgatgcca
    22081 aatacctcaa tatttacaat tcaattttca tcaaaaatat gataaaatag atgaataacc
    22141 gacttgagga gtgtggcatg ttaccagctt atataaaaat tcatgatgca attaaaaaag
    22201 acattgatct gggcatctgg ccaattggta gtcgcttacc aagtgaacga catttagcgg
    22261 aacatttcac cgttagtcga atgactctac ggcaggctat tacattacta gtagaagaag
    22321 ggattcttga aaggcggata ggaagtggta cttatgttgc cagtcatcgt gttcaagaaa
    22381 aaatgcgagg aacaacaagt ttcacagaaa ttatacgctc ccaaggacga caaccctcct
    22441 ctaaattatt atcctatcaa aagcaattag ctagtgatac cgaagttaaa gaattgaact
    22501 tagacaaaac agacttggtc attcgaatgg aacgtatccg ctatgcagac agtgtccctt
    22561 tggtgtacga aattgcttca atcccagaaa aatttataaa aacggttaaa cgagctgata
    22621 ttacagaaca cttttttcac tcattgatag caaatggtta cgagattggt aaaagtaaac
    22681 agacaatcta cgctaagcta gcaagtgagc gtgtagcctc ctacttggaa gttgctaaag
    22741 gacatgccat tttggctcta actcaggtgt cttactttac agacggcaaa ccttttgagt
    22801 atgtccgcag tcagtatatc ggtgaccgtt ttgaatttta cttagaaaat aattagtaaa
    22861 gaagtcattt atgacttcct tttttacacg aacagcataa ggcaattaat ttgctactgt
    22921 taaaaacaat catagtatga taaaatgaac attatggaaa ttgaaaaaac aaacaggatg
    22981 aatgcccttt ttgaatttta tgcagctttg ctaacagata aacaaatgaa ttatattgag
    23041 ctgtattatg ccgatgatta tagcttagct gagattgctg atgaatttgg tgtcagtcgt
    23101 caggctgtct atgataatat taagcgtacg gaaaaaattt tagagactta tgagatgaaa
    23161 cttcatatgt attcggatta tgttgttcga agtgaaatct ttgacgacat gattgctcac
    23221 taccctcatg atgagtattt gcaagaaaaa atttccattc taaccagtat tgacaataga
    23281 gaataagagg agttttgact atggcttttg aaagcttaac ccaacgtttg caagatgtgt
    23341 ttaaacacat tcgcggtaaa aagaaattat cagaatcaga tgttcaagaa gtgacaaaag
    23401 agattcgtct agctctttta gaagccgatg tcgctttacc agttgttaaa acctttatta
    23461 agcgcgtacg tgagcgcgct attggccatg agattattga tactcttgat ccaacacaac
    23521 aaattcttaa gattgttaat gaagaattaa cgagtatttt aggctcagaa accgcggaga
    23581 ttgataaatc tccaaaaatt ccaactatta tcatgatggt cggtttgcaa ggggctggta
    23641 aaaccacttt tgcaggaaaa ctcgctaata aattaattaa agaagaaaac gcgcgaccac
    23701 tgatgattgc tgccgatatt taccgtccag cggccattga tcagttaaaa acactggggc
    23761 aacaaatcaa tgtacctgtt tttgatatgg ggacagacca ctcagcagtc gatattgtca
    23821 gaaaaggttt ggaacaagct cgtgaaaacc gcaatgacta tgtcttgatt gatactgcgg
    23881 gtcgcttgca aattgatgaa aaactgatgg aagagctgcg cgatgtcaag gctttagcac
    23941 aaccaaatga aattcttttg gttgtagata gcatgattgg tcaagaagct gccaatgtag
    24001 cctacgagtt taatcatcag ttgagcatca caggggttgt gttaacaaag attgatggtg
    24061 atacccgtgg aggtgcagca ctatctgtcc gtgaaatcac tggaaaacca attaaattta
    24121 caggtattgg tgaaaaaatc acagatattg aaacatttca cccagaccgc atgtccagtc
    24181 ggattttggg aatgggtgac ttactcactc ttattgaaaa agctagccag gaatatgatg
    24241 agaaaaaatc cttagagtta gctgaaaaaa tgcgtgagaa cacctttgat ttcaatgatt
    24301 tcattgaaca gttagatcaa gtgcaaaata tggggcctat ggaagacctc ttgaaaatga
    24361 ttccaggaat ggctggtaac ccagctttgg ccaatatcaa agttgacgaa aaccaaattg
    24421 ctcgcaaacg tgctattgtc tcttcgatga cccccgctga acgtgaaaac cctgacttac
    24481 taaacccgag tcgtcgccgt cgtattgcag ctggttccgg gaacagcttt gtggaagtta
    24541 ataaatttat caaagacttt aaccaagcca aaagcatgat gcaaggggtt atgtcgggcg
    24601 atatgtctaa gatgatgaaa gatatgggca ttaatcccaa taatcttcct aaaaacatgc
    24661 ctgctggtat gccagatatg tcttccttag aagggatgat gggacaaggt ggtatgcctg
    24721 atttatctgg ccttggtggt gatatggata tgagtcaact atttggtaaa gggttcaagg
    24781 ggaaaattgg acaatttgcc atgaaacagg ccatgaaacg tcaagctaac aaactaaaaa
    24841 aagcaaagaa aaaacgaaaa taaaagagac ggaaattttc gtctcttttt gatgtgaaat
    24901 tcatttatct tgtatacaag attattaaaa ttatggaaga ccgcgttaca tgcatgatga
    24961 gttcatttaa aatttgaaat aacctaatca atctaactta aatttctaag ggcctaaaat
    25021 tagcgataat tttgccaata atgcgaggtt cttcgctata gggagcaaac ttatcagaat
    25081 attttttatt taaggacact agacgtaatc cctcatcttc acgaaatacc tttttgatat
    25141 atgtttgccc atcccattcg actgcataaa ttgctccatc gtaatcaaaa ctattttgtt
    25201 ttataagaac aacttcgcca tttaaataag ttggctccat agaatctcca aaaacccaag
    25261 acgcaaaatc gtattctaat tgttcatcgt aaaagacaac atcaaagtta ccatcaccaa
    25321 aataggagta accagtacca gcagataaac tttcatagac ccgataagca tataattgtg
    25381 atggtttatc tatgagatct ttagattttt tgtctatttg atgatttaac aatcgctctg
    25441 aatagccaat tactttttct ttattagata ttgtcagctg gttataaggc gttagcaatc
    25501 tatagtttgg gtcgaaataa tcagatgtca cattgaatag atgcaataag gcatttaaat
    25561 gtttttcatt tggtatattc ttaccttttt cccaattaga tattgtcatt ttattgacat
    25621 gcaacaatct tcccaattct gattgagtta ttccccttga taatcgtgct gtttttagtt
    25681 gatgtccaga aaacatttgg tagctccttt agtaaagtta taactttact aatagtatca
    25741 aaaaaataaa acgaaagcaa gtgtaacatt tcctacaatt aattcatgtg atagcaatac
    25801 tgtcaaaaag gggaaacacc taaaacatag cgactagatt tgtgtactag caggtctata
    25861 tctgataaag agttaattac tttaaagata aaattatcat ttagttctga gctaaacaaa
    25921 ttctgtgcct gaagttacta aaataatgat agtaaattat tactgaatct aaaagaagtg
    25981 acgttagtat ctgtaaaaaa agagatttgt ctcgtgacat ctttccgaaa aactgtaatt
    26041 ttcttgaaaa atatttatag gtgtgatata ctgctcttgt aaagaatgaa tggcataaaa
    26101 tacatgagac aatttgcgaa aattcatttt tgaaaaaatt gttattgtta aggaattatg
    26161 atgatatgag acgcgaatta ttactagaaa aaattgaaac ctataaggcc atcatgcctt
    26221 ggtatgtttt agattattac caatccaagt tagctgttcc atacagcttt accaccttat
    26281 atgagtattt aaaagaatac aaacgctttt ttgattggct gatggatgct gatttaacgc
    26341 aggcgccaaa gattgctgat attgacttga gcacgcttga gcaccttacc aagaaggatt
    26401 tagaggcctt tgtgctttat ttgcgggaac gaccttctct caacacctat tccaccaaag
    26461 agggtctttc tcaaaccact attaatcgga ccttgtctgc cttatcaagc ctttataagt
    26521 acttgactga agaggttgaa aatgaccaag gagagcctta tttttatcgg aatgttatga
    26581 aaaaagtgtc aacaaaaaag aaaaaagaaa ccctggcttc cagagcggaa aatattaagc
    26641 agaaactgtt tttaggtgat gaaactctag ctttcttgga ttatgtggat aaggaatatg
    26701 agcaaaaatt gtctaatcgt gccaaatctt ctttccgtaa aaataaggag agggatttgg
    26761 ctattatttc tctactactt gcttctggtg ttcgtttgtc tgaagcagtg aatcttgatt
    26821 taaaagatgt caatctaaat atgatgatta tcgaagttat tcgcaaaggc ggaaaacgtg
    26881 attcagtcaa tgtagcaggt tttgcgaaag gttatttgga gtcttattta gctgttcgtc
    26941 agagacgtta caaggctgaa aaacaggatc ttgctttctt tttaacagaa taccgtggcg
    27001 ttccaaatcg aatggatgct tctagtatag aaaagatggt tggcaagtac tctgaggatt
    27061 ttaaaattcg tgtgactcct cacaaattgc gtcatacgct agcgacaaga ctatatgatg
    27121 ctactaaatc tcaggtgtta gttagtcatc aattaggcca ttcctctact caagtcacgg
    27181 atctttatac ccatattgtc aatgatgagc aaaaaaatgc tttagataac ctttaatgtt
    27241 acataattgt ttttatgtaa cattaaaggt aaaaatagct tcaaaattaa ctttaataga
    27301 tggctactat taaccgtgac agtttggtgt cagaccgttt tccaaactac tcaagccact
    27361 tagaaaaagg aatatcactg ctaactttgt cccttctttg aatgactttt tttgcgatgt
    27421 ttatagatta aatctagtag ggttctcatc aaaaagatga gataagccta ttttta
//
LOCUS       DAUCXI010000024        25384 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.024, whole genome shotgun sequence.
ACCESSION   DAUCXI010000024 DAUCXI010000000
VERSION     DAUCXI010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25384
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.024"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            209..457
                     /locus_tag="VGY43_001078"
     CDS             209..457
                     /locus_tag="VGY43_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEQ4302268.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN"
     gene            494..1105
                     /gene="amaP"
                     /locus_tag="VGY43_001079"
     CDS             494..1105
                     /gene="amaP"
                     /locus_tag="VGY43_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEQ4302269.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFKIIVKGRLASRVAVADQIS
                     GVKEGIEKGLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            1116..1304
                     /locus_tag="VGY43_001080"
     CDS             1116..1304
                     /locus_tag="VGY43_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEQ4302270.1"
                     /translation="MEFYEKFKYPIIGGLVGLILAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1317..1856
                     /locus_tag="VGY43_001081"
     CDS             1317..1856
                     /locus_tag="VGY43_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ4302271.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1897..2097
                     /locus_tag="VGY43_001082"
     CDS             1897..2097
                     /locus_tag="VGY43_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ4302272.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKVK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            2108..2596
                     /locus_tag="VGY43_001083"
     CDS             2108..2596
                     /locus_tag="VGY43_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ4302273.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEAASVTVQDRVTSAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            2759..3400
                     /locus_tag="VGY43_001084"
     CDS             2759..3400
                     /locus_tag="VGY43_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ4302274.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICSQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(3543..4085)
                     /locus_tag="VGY43_001085"
     CDS             complement(3543..4085)
                     /locus_tag="VGY43_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEQ4302275.1"
                     /translation="MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            4203..4904
                     /locus_tag="VGY43_001086"
     CDS             4203..4904
                     /locus_tag="VGY43_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302276.1"
                     /translation="MAFIELKQVSKSYQVGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            4919..7555
                     /locus_tag="VGY43_001087"
     CDS             4919..7555
                     /locus_tag="VGY43_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEQ4302277.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELVVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSNLRLTNAFS
                     KDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRAALAKETVKLAASEENL
                     TFLEGSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLPDKQSISILSSSTTSLSPYFNLLDC
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSNTYFRNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNVNHIKSVQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVILSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            7647..8243
                     /locus_tag="VGY43_001088"
     CDS             7647..8243
                     /locus_tag="VGY43_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ4302278.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLINL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDLPIGQALLDAADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            8254..9210
                     /locus_tag="VGY43_001089"
     CDS             8254..9210
                     /locus_tag="VGY43_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ4302279.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGSQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMAINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            9307..10647
                     /locus_tag="VGY43_001090"
     CDS             9307..10647
                     /locus_tag="VGY43_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEQ4302280.1"
                     /translation="MNEIKCPHCHTLFTINESEYSQLLEQVRGQAFDEELQKRLINEI
                     ALLEEKAKHQLHEVVAKKETAITSLTNQLEQIEKEQAYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVVSLTNQLDKLALEKDATFQSKLATIEKERDGIKNQL
                     ALQAKESELSLASVRSDYEAQLKAANEQVEFYKNFKSQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFAKDNQLSSRGSKGDYIYREVDANGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKGCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAAMNSLHYKQELALIKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVKRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFEALKDQ"
     gene            10763..11647
                     /gene="truB"
                     /locus_tag="VGY43_001091"
     CDS             10763..11647
                     /gene="truB"
                     /locus_tag="VGY43_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEQ4302281.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            11676..12608
                     /locus_tag="VGY43_001092"
     CDS             11676..12608
                     /locus_tag="VGY43_001092"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEQ4302282.1"
                     /translation="MEIEYIKDYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVAN
                     KEGLKVVVFTFTESPKLAFLRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNCTDSDYLTRNFEGQVYTIEEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            12651..13055
                     /locus_tag="VGY43_001093"
     CDS             12651..13055
                     /locus_tag="VGY43_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEQ4302283.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDVDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            13057..13335
                     /locus_tag="VGY43_001094"
     CDS             13057..13335
                     /locus_tag="VGY43_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEQ4302284.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLNS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            13325..14113
                     /locus_tag="VGY43_001095"
     CDS             13325..14113
                     /locus_tag="VGY43_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEQ4302285.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAVTLEDQ"
     gene            14116..15426
                     /locus_tag="VGY43_001096"
     CDS             14116..15426
                     /locus_tag="VGY43_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEQ4302286.1"
                     /translation="MMSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAA
                     PGGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALAMLKPGGELI
                     YSTCTWAPEENEDVVQWLLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLIKDQLRLWKMFEKDHINLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFRPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
     gene            15565..16431
                     /locus_tag="VGY43_001097"
     CDS             15565..16431
                     /locus_tag="VGY43_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEQ4302287.1"
                     /translation="MKMKKKFFLLSLLVLSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            16442..17377
                     /gene="pstC"
                     /locus_tag="VGY43_001098"
     CDS             16442..17377
                     /gene="pstC"
                     /locus_tag="VGY43_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEQ4302288.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFIDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTVLSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPSSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            17367..18254
                     /gene="pstA"
                     /locus_tag="VGY43_001099"
     CDS             17367..18254
                     /gene="pstA"
                     /locus_tag="VGY43_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEQ4302289.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSARFIGKKLHSKMTAAK"
     gene            18270..19073
                     /gene="pstB"
                     /locus_tag="VGY43_001100"
     CDS             18270..19073
                     /gene="pstB"
                     /locus_tag="VGY43_001100"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302290.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            19086..19844
                     /gene="pstB"
                     /locus_tag="VGY43_001101"
     CDS             19086..19844
                     /gene="pstB"
                     /locus_tag="VGY43_001101"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302291.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            19912..20565
                     /gene="phoU"
                     /locus_tag="VGY43_001102"
     CDS             19912..20565
                     /gene="phoU"
                     /locus_tag="VGY43_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEQ4302292.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            20770..23307
                     /locus_tag="VGY43_001103"
     CDS             20770..23307
                     /locus_tag="VGY43_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEQ4302293.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTPRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     GALRFNIDNTAHYITDYQGSLLDALVTELAQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNQHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQNNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQSTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
     gene            23654..24328
                     /locus_tag="VGY43_001104"
     CDS             23654..24328
                     /locus_tag="VGY43_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4302294.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGY
                     ILKNNE"
     gene            24321..>25384
                     /locus_tag="VGY43_001105"
     CDS             24321..>25384
                     /locus_tag="VGY43_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ4302295.1"
                     /translation="MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYS
                     SVDSSLVSVSNNASSYANRTMARISSFYFDTENNIIKALPDSDSSKLLGTPAANTDII
                     LFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
                     PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILENSEHLASSLDEVRNMRILTTNL
                     LNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQNQVNRSLRMDKALLK
                     QLITILFDNAIKYTDKNGII"
BASE COUNT         8077 a         4176 c         5209 g         7922 t
ORIGIN      
        1 gtggtcactt tataaaatat tatcaaaata acattttata ggattttgaa atatcggtat
       61 tcaaacaaaa aataaactaa cactttatta tttagtttat atagtcactt tttgaaagtc
      121 gactattaaa agactattgc ttgaagaata acagctgtta ttcttccttg gacaaaaggt
      181 acaggagtat ctaaaaagga gaattatcat gggacttatt tggactttaa tcgtcggtgc
      241 gcttattggt gtgattgctg gagcacttac taaaaaaggt ggttcaatgg gctggattgc
      301 aaacatcgct gctggtctag ttggttcttc cgttggtcaa gctttacttg gttcgtgggg
      361 cccttcttta gcaggaatgt ctttgatccc gtcagttatt ggtgccgtta tcgttgttat
      421 gatcacttct tttgtactaa acaaaactaa caactagttt cctctttatt tagtaagtac
      481 ttacaaatag agaatgttaa gtagaaaaga ggtctgtatg tcaaaattgt taaagattag
      541 ttattgtctt gtcggacttg ttctattgtc tgtttttgga tgggtagttg gaataaccgg
      601 aggctatata tatttacctt atagttatcg ttggctaagt tggggtatgg atagttttcc
      661 caatctctta gattcagctt tatcctatta ttacttctgg acagcccttg tattatttgt
      721 tataacattt cttgccttat tagttattat tttataccca agaatttata ctgaggtcca
      781 gttacgccat aaaaataaaa aaggaacact tttattaaaa aaatcggcta ttgaaagtta
      841 tgttgcgacc gctattcaaa ctgcaggttt gatgccaaac ccaacagtca cagctaaatt
      901 atataagcgg aagtttaaga ttatcgttaa aggacgttta gcttctcgtg tagcagtggc
      961 agatcaaatt agtggcgtga aagaagggat cgaaaaaggt ttaactgagt tcttcggaat
     1021 taattatcct gttaatttca aagtttatgt taaagatatt gctgattctg atcgtaaaca
     1081 tattaccaga aatcgtgtag aataggagat ctatcatgga attttatgaa aaattcaagt
     1141 accctattat tggtggcttg gtggggctaa ttcttgccat attgctcatg gcttttggtt
     1201 tattcaaaac gctactagca attattttca ttattttagg gatatatggc ggcctgtatg
     1261 ccaaaaaaac aggtattatt gatcaatttc ttaatcgcaa ataaaggaga cttattatga
     1321 ctgaaactta tattaaaaac acatctaaag acttaacttc agcaattcgt ggtcaattaa
     1381 catatgatga taaagtaatt gaaaaaattg ttggtttagc acttgaaaat gttgatgggt
     1441 tactgggtgt aaatggtggt ttttttgcta acctaaaaga taaattagta aacaccgaat
     1501 ctgtacgtga tggcgtgaac gtggaagttg gaaaaaaaca agttgccgtt gatcttgata
     1561 ttgtcgctga atatcaaaag catgtgccga ctatttatga ctctattaaa tcaatcgttg
     1621 aagaagaagt gaagagaatg accgatctgg atgtgattga agttaatgtt aaagtagtcg
     1681 acattaaaac aaaagaacaa tttgaagctg aaaaagtaag tttacaagac aaagtttcag
     1741 acatggcacg ttcaacatct gaatttacga gtcatcaagt tgagaatgtt aaagcttcag
     1801 tggataacgg tgttgaaaaa cttcaagatc aaaaagctga gccacgtgta aaataattat
     1861 atgtcgtcaa ttaggtaagc taaaggaggg tttattgtgt cagatgaaaa atataatgcg
     1921 aaattagatc aagctggtgg caagttaaaa gaaggatttg gtaagatttc tggagataaa
     1981 tctttagaaa ctgaaggtaa agtagataaa gttactggaa aagttaaaga ggttattgca
     2041 gacgccaaag atactgtaaa aggattagct aaaggcttag ataataaaga taaataaagg
     2101 ggacatgatg gaaaaaactc aaattaaaag cactcttact tatgacgata aggtcatcga
     2161 aaaaattgtc ggtcatgctt tggaaaacgt tggcggatta ctagctgtaa caggtggatt
     2221 tttctcaaat atcaaaaata atttggtgaa ttctgagtct gtaactgatg gtgtttcagt
     2281 tgaagttggt agcaaggaag tagcagttga tttagcaatc attgtagaat acggtaaaga
     2341 tattcctgct attgcagaat ctattaaagc tattgtttct caaaacgttg acagtatgac
     2401 acatttgaaa gttgttgaag tcaatgtgaa cgttgttgat attcgtacta aggaagaaca
     2461 tgaagctgct agcgttactg ttcaagatcg tgtcactagt gcagcttcaa gtacttcaca
     2521 atttgtatca gaacaaacag aaaaattaaa agatactatc tctgatactg taaatagtga
     2581 tgaggcagct aaataagcaa tcgtctagga agtattattg actagtggtg ataagtttga
     2641 gctggtattt accagctctt tttgtcacgg ttaaaaagat acggactatt gtcatctctc
     2701 taaaaatatg atttaattag atagaaattt ttcaaattgt tagaaaggag taaattaagt
     2761 gataagtcct aaaaaagaga taacaagttc aaaatatcaa aaaattgcta tttcagtagc
     2821 tcagcgtatc gcaaatggcg aatatgaagt gggcgaaaag ttaaagtcaa gaactactat
     2881 cgcctcgaca tttaatgtat caccagaaac ggctcgtaaa ggcctgaata ttttagctga
     2941 cttgaaaatt ttgactttaa aacatggtag tggagctatt gtgctgtcaa aagaaagagc
     3001 tattgagttt ataaatcaat acgaatcaac ccattccatc gctgttttaa aagaaaaaat
     3061 acgtgagact attaatgatc agggaaaagc aatggaaaaa atggctgttt tggtcaatga
     3121 ttttttaatg caaagtcaat ctgttagtaa gcaataccca ttagcacctt atgagattat
     3181 ttgtagtcaa gattcggaac attttggcaa atctattggt gtgttaaata tctggcacca
     3241 gacaggagca actatcgtcg ctattgaaca tgctggtcag tttatcgttt caccaggtcc
     3301 ttattctgtt attgaaaaag gcgatcatat ttatttcgtt ggtgatgagt cagtcatttc
     3361 acgaatgaag acctttttta atttacgaaa aggattataa gtttgaggac ccacctcaaa
     3421 ctttttttgt tgctgtttag cattattaaa agaggcagat catcatggtt tgtctttcca
     3481 aaatatctgt ttagacagtt gttttggatt gggagcatga tttcagactc ttttgatgtt
     3541 ttttaattgt ctagagtaac tgctttgaga ataatatcgg caacctcttc agtggtttct
     3601 tgatagccat tagcaatcca atagctgata atgctctcaa tactggcaag gtaaacttct
     3661 aaagcatagg gataaggaat atggtattga ttggtcacaa tgtcttggaa accagtaata
     3721 gtagtcaaaa attggtaaca gaaatccttg atgagttgcg gaaatttgag gtaagaaata
     3781 gtagcgagtg cggttataaa ttctctatgt tctataaggt aggacaaggt ttgattgagg
     3841 acttgtcgag tgtctgtgta gatttcagcc tgatttaaca aacggtacaa atcatccaga
     3901 gtgtcatttt tgaagtgatt catcatgtca aatttatcag tgtagtggag gtagaaggtt
     3961 cctctattga taccagcctt tttagtaagg tcagagacag taagagtttc aaaagattgt
     4021 tcagttagta aggtggttaa ggcggtcttt acataagctt tggtttcagt atgtcttttg
     4081 gtcattctca ggtgctcctt aaatcaacag ttgcgtcaga tttgttcttg ttaaatactt
     4141 agggccatta tataataagg ctataattaa atcaacacta tgttcaaata atggaggggc
     4201 agatggcttt tattgaatta aaacaggttt caaaatctta tcaggtagga gagacgactg
     4261 tttttgccaa ccacgaagtg tcttttgaga ttaataaagg agaactagtg gttattttgg
     4321 gagcatccgg agctggtaaa tcgacagtcc tcaatatttt ggggggcatg gacacagtag
     4381 atgcaggtca agtaattatt gatggcaaag acattgctca ttacacatct aaggccttaa
     4441 ctcagtatcg tcggaatgct attggtttcg tttttcaatt ttataatttg gttcctaatt
     4501 tgacagctaa agaaaatgtt gaattagcag ttgaaattgt agcagatgct ttagatcctg
     4561 tgaccatttt aaaggaagta ggactcagtc atcgtttgga tcattttcct gctcagctct
     4621 caggtggtga acagcaacgg gtttcgatag cacgtgcctt agctaaaaac cctaaattgc
     4681 ttctttgtga tgaacctaca ggtgcccttg actaccaaac aggaaagcaa attctaaccc
     4741 tcttacagga tatggcacga actaagggga ccacggtagt tattgtaacc cacaatgctg
     4801 ctattgctcc gatagctgat cgtgtcattt ttatgcatga tgcacaggtt accaagacag
     4861 tcattaataa ggaacctgca agcattgaga caattgatta ttaagaggaa ggtgtcgtat
     4921 gataaagaaa accttatgga aggatatttt gagagctatc aagaatagta aagggcgatt
     4981 catttcctta tttttcctaa tggccttagg ctcctttgct ttagttggac ttaaagtcac
     5041 cggtccagat atggaacgaa cagccagccg ttacctcgaa agacaccagg tgatggacct
     5101 aacggtactg gcttctcatc aattttccca agccgataaa caagagttag atacgttaaa
     5161 aggggctcat ttagaatatg gtcatttact tgatgtcagt ctaactagca accagaaatc
     5221 tcttaggctc tatagcgtgc caaagaaagt gtctaagcca gtcttggtta aagggagttg
     5281 gccaaagcga gagacagatt tggttttatc ctcctcactt gctaaaaact atcagattgg
     5341 agatgaacta gtagtcacct cacctatgga aggtttgctg acgacaaccc attttcaagt
     5401 ggttggtttt gcgaattctt cagaagtttg gtccaagtcc aatttaggaa gttcctcaac
     5461 cggagatgga agtctctacg cttatgcttt tgttaatcca aacgttttta aaagtgcctt
     5521 taacctgctg cgcatccgtt ttagtaatct tcgtctgaca aacgcttttt ccaaagacta
     5581 tcaaaaaagg gtaacccaaa accaagctca tttggataat ctacttaaag ataatggcca
     5641 gaagcgttat gatgacctcc aaaatcagta tgaccttgcc ttaaaaaatg gcagagcagc
     5701 acttgcaaag gaaacagtga aactagctgc gagtgaggag aacttaactt ttttagaagg
     5761 ctctgcttta caagaagcta agcatcagat tgaacaaggc aaacaagcat tagccaagga
     5821 ggaaaagcag ttagagcagg tgcaggctac aaaagataag ctagaaaaac ccagttacct
     5881 gacttataat cgctcgaccc taccaggagg agaaggatat catacttatg caacttcaac
     5941 gacctccatt tcaaatgttg gaaatatttt tcctgttgtt ctttatctcg tagctgctct
     6001 agtagccttt accaccatga cacgttatgt tgatgaagaa agaacaagct ctggtctatt
     6061 aaaagccatc ggttattcta acaaggatat cagtttaaag tttcttatct atgggctttt
     6121 agccagtttt ttagggacaa ctttaggtat tattggggga acttacctct tatctgcctt
     6181 gatttcagag atcttaacag gagctttgac tattggaaag actcaccttt atagttattg
     6241 gttttataat ggcatagctt acttgctggc tatgttatct gctgttttac cagcctactt
     6301 aattgtcaaa aaggaattat tcctcaatgc agctcagtta ttgctgccca aacctcctag
     6361 taagggggca aaaatctggt tggaacacct gacttttgtc tggaaagctc tgtcctttac
     6421 tcacaaggtg accatacgta atatttttcg ctataaacaa agaatgctga tgaccattgt
     6481 aggcgttgca ggctctgtag cccttttatt tgcaggctta gggattcagt cgtcattagc
     6541 caaagtagtt gagcatcaat ttggtgattt aacgacttat gatattttgg ctgtcggttc
     6601 ggccaaagcg acagcgacag agcaaactga cttagctagc tatcttaaac aagaacctat
     6661 tacagggtac caaaaggtat cttatgccag cttaaccctt cctgtaaagg gattacctga
     6721 taagcaaagt atttccattt tatcaagttc aactacctct cttagcccct attttaatct
     6781 gctggattgt caggagcaaa agaaggttcc cattccaacc tctggtgttt tgatttctga
     6841 gaaattagcc tcttattaca aggtaaaacc aggtgatcag ttggtattga ctgatcggaa
     6901 aggacagtct tataaagtga cgattaaaca ggttattgac atgacagttg gccattacct
     6961 gataatgtct aatacctatt ttaggaatca ttttaaagga ttggaggctg ctcctgccta
     7021 tctgattaag gtaaaagaca aggatagcaa gcacataaag gagacagcca gtgacttgtt
     7081 aaccttaaaa gcgattagag cagtttcaca aaacgtcaat catattaaat ctgttcagct
     7141 agtagtcacc tctcttaatc aggtcatgac cctccttgtc ttcttgtcta ttttattagc
     7201 aatcgttatc ctttataact taacgactat taatattgct gagcgtattc gagaattatc
     7261 cactattaaa gttctgggat tttacgatca ggaggtcacc ttatatattt atcgagaaac
     7321 tatttcgcta tccctagtag gcattctttt aggtatctat ttaggaaaag gcctgcatac
     7381 ttatatcatg acaatgattt caactgggga tattcaattt ggtgtaaagg ttgatgctta
     7441 tgtttatcta gtgccaattc tagtaatcct tagcttgtta gcggtattag gtatctgggt
     7501 taatcgccat ttaaaaaagg ttgatatgtt agaagctttg aaatccatag attgattggt
     7561 gaaaagacag agatagacag cacttgaaaa gttaatcata ttatgatagt atctaaatac
     7621 tataatttaa tagaaagata ctatgtatgg aaaatagcat tgaggcctat ctagcagata
     7681 gcagagaaaa ggtaacatta ggtacagttg ttgattgttt taaaggaaaa gcagtctcaa
     7741 gtaaggttgt gccaggtgat gtgggattga ttaatttatc tgacatgggc accttaggaa
     7801 ttcaatatca ccaattaaga actttccaga tggatcgtag gcagctcttg cgttaccttt
     7861 tggaagacgg agatgtctta atcgcctcta agggaaccct aaaaaaagtc tgtgtttttc
     7921 ataagcaaaa tcgagatgtg gtggcatcat caaatatcac tgtcttacgc cctcaaaaac
     7981 tgttaagggg ctactatatc aagttctttt tggacttacc tattggtcaa gcgctcttgg
     8041 acgcagcgga ccatggcaaa gatgtgatca atctctcaac gaaagaattg ttggatattc
     8101 caattcccgt tattccttta gtgaaacagg attatttgat taatcactac ttgagaggat
     8161 taacagatta tcatcgtaaa ctcaatcgag cagaacagga gtgggaatat attcagaatg
     8221 aaattcaaaa aggattaggt taggagtctt gtcatgggtt cagttgaacg tacattaaaa
     8281 atgaccttgg ctaccattgt tgccatttta attgcttacc aacttcatct ggattatgca
     8341 atgtcagcgg ggatcattgc cctgttaagt gttttagaca cccgtaagtc cagtttggtg
     8401 gtcgctagga atcgcttgct atcttttttc ctggcttttg ggattgcgat gatgtgcttt
     8461 agcttgtttg gttttacgac agtaggtttt atgtgttatt tgttaattat tattcctttg
     8521 ctctatcact ttcagataga ggcaggactg gttcctataa cagtacttgt gacacatttg
     8581 attgctaaaa agagtattgc attacctatt ttatcgaatg agtttatgct cttttttgta
     8641 gggactagtg tcgctttact atttaatgct tatatgggtt cacaagatca gcaaattcgg
     8701 tactatcacc aaaaagttga atcggatctg aaaggtatct tataccgttt tgaaagtttt
     8761 ctactggaag gaaaaggtca aaatgaaggg ctcttgatca aaaaccttga taaaatatta
     8821 gatgaagctc taaaactagt ttatcgagaa aggcataatc aactatttca gcagaccaat
     8881 tatcaagttc attattttga gatgcgacga caacaaaata gactattggg acaaatggct
     8941 atcaacgtaa acacgttaat gagacaaagt aaggaaagta ttcttttgtc acatcttttt
     9001 cacgaaactg cttgtcagct aagcgaacaa aatccggctt taaccttgat tgatgacatc
     9061 gaacaattgc ttgaaacctt tcgtcatggt gatcttcctc aaactcggga ggaatttgag
     9121 cgacgtgcgg ttttatttca gctcttacaa gacttagagc gctttatctt attaaaggta
     9181 gagttttatc aggattatca aaatgactaa atctctattg cacacttctt atctatgaca
     9241 gcttgggact taacttcctg agcttttttg ctataataaa aagaagaatc tcagaatgga
     9301 gacaagatga acgaaataaa atgccctcat tgtcataccc tatttactat caatgagtca
     9361 gagtatagtc aattattgga acaagtcaga gggcaagcct ttgatgaaga attgcaaaaa
     9421 cggctaatca atgagatagc cttgctagaa gaaaaagcga agcatcaatt gcatgaggtt
     9481 gtcgcaaaaa aagaaacagc tattaccagc ttgacaaacc aattagagca aattgaaaaa
     9541 gaacaagcct acctcagaca agaagaactg gctaaaaaag accagcttat tgcttcttta
     9601 gaagcgaaac ttgataaatt agcctcacaa aatgctttgg aactggccaa tcaattagct
     9661 gagaaggaca aagaagtggt tagtttgacc aatcagctgg acaaattagc acttgaaaaa
     9721 gatgccacgt tccagtcaaa gcttgctaca atcgaaaaag aacgcgatgg aatcaaaaac
     9781 caattggcgc ttcaagctaa agaaagtgaa ttgtcgttgg cttcggtgcg cagcgactac
     9841 gaagcacagt taaaagcggc taacgagcaa gttgaatttt ataaaaattt caaatcgcag
     9901 caatctacca aagcaatcgg agagagtcta gaactctatg ctgaaacaga gttcaataaa
     9961 gtaagaagtt atgcttttcc caatgctagc tttgctaaag ataatcaatt gtctagtcgt
    10021 gggtcaaaag gggattatat ttaccgagag gttgatgcca atggtgtaga aatcctctct
    10081 atcatgtttg aaatgaaaaa cgaggcagac accaccaaaa caaaacataa aaatagtgat
    10141 tttttcaagg agttagataa agaccgtcgc gaaaaaggtt gtgagtatgc tgttttggta
    10201 agcatgttag aagctgataa tgattactac aatacaggga ttgttgatgt cagtcatgaa
    10261 tatcaaaaga tgtatgtggt tcgtcctcaa ctctttatcc agttgatagg gattctgcga
    10321 aatgcggcca tgaatagttt acattataag caagagttgg ccttgattaa ggaacaaaat
    10381 attgacatca ctcacttcga agaggatttg gaccaattta agaatgcctt tgctaagaac
    10441 tatcagtctg ccagcaacaa ctttaaaaag gctattgacg agattgataa atcgattaaa
    10501 cgcatggagg aagtgaaacg ctttttaacc actagtgaaa atcagttacg cttagctaat
    10561 aataaattag aggatgtttc agttaaaaaa ctgacccgcc aaaacccaac catgcgagag
    10621 aaatttgaag ccctcaagga ccagtaagcc tgaaagtgag tctttccctg ctaaaattgg
    10681 ttaagcgttt attttgggaa aactgatgat aaagcggtag aatagaatca gtaataatta
    10741 ctaattagag agaaaaatag acatgataaa tggaatcatt aatttaaaaa aagaagccgg
    10801 catgacctct catgacgcag tttttaaatt acggaagttg ttacaagaaa aaaagattgg
    10861 acatgggggg accttagatc ctgatgtggt cggtgttcta ccaattgcag ttggtaaggc
    10921 tactcgtgtg atcgaataca tgacagaagc tggtaaagtt tatgaaggac aagtgactct
    10981 cggttactca acaacgactg aggatgctag tggagaggta gttgcgaggt cctctttgcc
    11041 agctgtgcta acagaagaac tcgttgatca aacgatgacg actttccttg ggaaaatcac
    11101 acagacccca cctatgtatt cagccgtaaa ggttaatggc cgtaaattat acgagtatgc
    11161 gcgtgctggt gaaagtgtgg aacgtcctag aagagaagtg actatttctc tgtttgaacg
    11221 caccagccct ttgaatttta ctgaagacgg tctttgccga ttctctttta aagttgcttg
    11281 tagcaaaggg acttatgtgc ggaccttagc agttgattta ggtcgagctc taggggtaga
    11341 gagtcatatg tccttcttgc agcgatcagc ttcagcagga ttaaccctcg agactgccta
    11401 tactttggga gaaattgctg atatggtttc taaacaagag atgtcttttt tgttaccgat
    11461 cgagtatggc gttgctgatc ttcctaaaat ggttattgat gatactgaat tgactgaaat
    11521 ttcatttggt cgccgtctta gtctccctag tcaagagcca ctgttagctg cttttcatgg
    11581 cgaaaaagta attgctattt tagaaaaaag agatcaagaa tacaaaccca aaaaagttct
    11641 tatttaaata gtttgagtaa gtagaatgga taattatgga aattgaatat atcaaagatt
    11701 atcgtgatat taaccaagaa gatgatacag tcttggtatt gggatatttt gatggattac
    11761 accgtggtca taaagcctta tttgacaaag caagagaggt tgcaaataaa gaagggttaa
    11821 aagtagtcgt ttttacgttt acagagtctc cgaaattggc ttttttgcgt ttttctcctg
    11881 agttattgct tcatattact tatccaaaga agcgttatga aaaatttgcc gattacggtg
    11941 taaataaatt atatttggtt gattttactt ctaaattctc taaggtctca tctgatcatt
    12001 ttataactca ttatattaaa aacctgaaag caaagcatat tgttgtcggt tttgactata
    12061 agtttgggca taattgtaca gatagtgatt atttaaccag aaattttgaa ggacaagttt
    12121 ataccattga ggaaataaaa gaagatcatc gaaaaatttc tgctacatgg ataaggaagc
    12181 ttattcaaga aggtaatgta gttaaagcaa accacttgtt aggctatgac ttatcgacaa
    12241 gggggagagt cgttcacggg gatgcgcgtg gccgtactat tggtttccca acagccaatc
    12301 tagctccaat tgacaacaca tacttaccag ctgatggagt ctatgttaca aatgttattg
    12361 ttgctaataa aatctatcgc tctatgacga gtttaggtaa aaatgtgaca tttgggggga
    12421 aagagttgcg tctagaagtt aacatttttg actttgacga agagatctat ggagaaatta
    12481 ttgagattgt ttggttagat aagattcgag acatggaaaa attcgaggga atcgaagatt
    12541 tgactgatag attggaatat gataaacgaa cagcattaaa ttggaaaaaa gatagcaaat
    12601 tatcttaaat ttttgtataa taaggtaagt aaatttgata gaggaaaaat atggttacct
    12661 tatttttatc acctagctgt accagttgtc gtaaagcaag ggcatggtta gtaaaacacg
    12721 aagttgactt tcaagagcat aatattatta caagtccatt aagccgtgat gaattaatgt
    12781 caatcctctc ttttacagag aatggaacgg aggatattat ttcaacacgt tcaaaggttt
    12841 ttcaaaaact tgatgttgat gtagaagagc tttcaatttc agatttaatt gatttaattg
    12901 ctaaaaatcc aagtcttctt cgtcgcccta ttatcatgga tcaaaaacgc atgcaaattg
    12961 gttttaatga agatgaaatt agagcgtttt tatcgagaga ttatcgcaag caagaactac
    13021 gtcaagcaac gataaaagca gaaattgagg ggtgatatgt caggtaatta ttattatcca
    13081 cttgacttaa gttggagcac tgaagaaata tcctcagtgc ttcatttttt gaataaagtg
    13141 gagttagcat atgaaaaaaa agtagatgca aaacaactcc taaatagtta taagacttat
    13201 aaaaccattg tcaaaagtaa agctcaggaa aagcaaatcg accgtgattt tcagaaagtt
    13261 agtggttatt cgacctatca agttgttaaa aaagcgaagg caattgagaa aggattcttt
    13321 tcccttggaa actaaatacg catttgcaag gcaaatcatt aaagaagcag ggctttttat
    13381 caagtcaaaa atgtcagagc agctagatat tcaggtgaaa acacaatttg atgatctggt
    13441 taccaatgtt gatcaagaaa ctcaacagtt actgatggat cgtattcatc agacctatcc
    13501 ttgtgatgcc attttagctg aagaaaatga cgttcgtcac cccattaatc aaggaaatgt
    13561 ttgggtcatc gatcccattg atggaacggt taactttatt gtgcagggat cacagtttgc
    13621 agtgatgatt gcctattatg aacaaggaat tggccaattt gggcttattt atgatgtgat
    13681 ggcagatcaa ttactagctg gtggtggtga ttttgaagtt actttaaacg gtgataagct
    13741 tccagcttac caagaaaaac ctttagagcg tagcttaatt ggctgcaatg caggcatgtt
    13801 tgccagaaat gatcgcaacc ttgctcatct aattgcaaag actttaggtg taagggttta
    13861 tggtggtgca ggtatctgca tggttaaggt catgaagcag gaattactgg cctatttttc
    13921 atttatccaa ccatgggatt acgcagcagc aaaagtacta ggcgataaac tgggttatgt
    13981 tttactaact attgacggat atgagcctga ttttcaaaca cgtcaaaaaa tcatgtttgt
    14041 tcctaaatgc caactcacta ggatagcgtc ttttctaaca aaggactctg ccgtcacact
    14101 tgaagatcaa tagaaatgat gtcattacca aaagaattta ttaacactta tcaagcaata
    14161 ctaggcaaag aattagaaga tttcttggca agttttaacc aagagccggt caatgctttt
    14221 cggattaacc ccttaaagaa tcaactaaaa acctttgaac accccattcc aaatacctta
    14281 tggggatatt atggtaaact atctggcaag tctccagagc atgtgtcggg gttggtttat
    14341 tcccaagaac cagcggctca aatggtggca caagtagcgg ctcctcaaaa ggggagtcgt
    14401 gttttagact tggcagctgc accaggagga aaatcaactc atttattagc ttatttagac
    14461 aatacaggtc ttttagtcag caatgaaatt tctaagaagc gcagcaaggt tttagttgaa
    14521 aatatcgaac gttttggcgc tagaaatgtt gtggtgacta atgaatccgc agatcgttta
    14581 gccaaggtat tttctcatta ttttgatact atcgtctttg atggaccatg ttctggtgaa
    14641 ggaatgtttc gcaaggaccc tgatgctatt caatattggc atcacgggta tcccgcagaa
    14701 tgtgccaagt tgcaaaaatc tattttagaa gacgccttag ccatgttaaa accaggagga
    14761 gaattgatat actccacctg tacttgggct cctgaagaaa atgaagatgt tgtgcagtgg
    14821 ctcttagaga cttatacctt tttagaattg gtcgatgttc caaaactaaa tggaatggtt
    14881 agtggtatcg gacttccaga gactgctaga atgtaccctc atcgttatca aggggaaggg
    14941 caatttgtgg ccaagctaaa agataagcgt caagaaggac aaagcactaa actaaaagca
    15001 cctaaatcca acttgatcaa agaccagtta cgtctttgga aaatgtttga aaaagaccat
    15061 ataaacctta ccctatcagg aacactacaa acctttggtg attacctata cctcttgcca
    15121 gatggtcttc ctgctttaga tggccttaaa attgctcgga acggtttaga attaggcgtc
    15181 ttcaagaaga aacgctttga accctcttac gccttgggat tagctttaaa gcctgatgag
    15241 gtccgatcat ctattgagct tagagaggaa gactttagac cttatgtgtc aggtaacgtc
    15301 attactttgc cccaatctta tccaacaggc tggtaccaat tactcattaa tggcaatggt
    15361 ctaggatttg ccaaggtcgt tgacaagacc atcaaaaata atttccctaa agggttaaga
    15421 ttttagcgta aaaaataaga ttaaaaagtt aaatatttaa agaaaaaatg ctttcaaagc
    15481 ataggtagat atgttactat aaagaatatg tggcacttag tttctacata tatacccttt
    15541 atttttacga ataggaaata aataatgaaa atgaaaaaaa aattcttttt gttaagtctt
    15601 ttggtcctat caactttctt tttatccgca tgttctagct ggattgataa aggtgagtca
    15661 ataaccgctg taggatcaac agcactacaa cccttagtag aagcagtagc tgatgaattt
    15721 ggaagcagta atctaggcaa gactgtcaat gttcaaggtg gtggttcagg tacagggttg
    15781 tctcaagttc aatcaggagc tgtccaaatt ggaaatagtg atgtctttgc ggaagaaaaa
    15841 gatggtattg atgcttctaa attagttgat catcaagtag ctgttgcagg acttgcagtt
    15901 attgccaatc ctaaagtcaa ggtttccaat ctcagtagtc agcagttgca aaagattttt
    15961 tcaggagaat ataccaattg gaaacaagtt ggaggagaag atcttgcgat ttcagtgatc
    16021 aaccgagcag caagttctgg ctcacgagca acctttgaca gtgttatcat gaaaggggtc
    16081 aacgctaaac aaagtcaaga gcaagactcc aatgggatgg ttaaatcgat tgtttcacaa
    16141 acaccaggtg ccatttctta cctttccttt gcctacgttg attcatctgt taaatctttg
    16201 caattaaatg ggtttaaggc aaatgctaag aatgtggcta caaatgattg gccaatctgg
    16261 tcctacgaac acatgtacac caaagataaa ccaacagggt tgaccaagga atttcttgat
    16321 tatatgtttt cagatgaagt acaacagaac attgttacac atatgggata tatttcgata
    16381 aatgatatgg aagtggtcaa atctcatgat ggaaaagtaa caaaaaggta atggaggaat
    16441 tatggaaaat caggaattgg ctaaaaaatt agcctcacca tcaaagaatt caagacttga
    16501 aacctttggc cgcaccatta cgtttttgtg tctggctttg attgttttta tcgttgcgat
    16561 gattctgatc ttcgttgctc aaaaagggtt gtcaaccttc tttattgaca aggttaatct
    16621 ttttgatttc ttgtttggaa aggagtggca accaagtgtg aaaaatgcgg ccggcattcc
    16681 ttatcttggt gctctgccaa tgatcacagg atcctttttg gttaccgttt tatctgctat
    16741 tattgccacc ccatttgcca ttggcgcagc cgtttttatg actgaaatct cacctaaata
    16801 tggcgctaaa ttattacagc ctgcggttga gcttttggtt ggaattcctt cggttgttta
    16861 tgggtttatc ggtttgcaag tgattgttcc ttttatgcgc tctatctttg gtggcacagg
    16921 ttttggaatc ctatctgggg tctgtgtctt gtttgttatg attttaccaa cagtgacttt
    16981 tatgacaaca gacagtctgc gggcggtgcc tcgtcattac cgcgaagcgt ctatggctat
    17041 gggagcaaca cgttggcaaa ccatttggcg tgttgtcctt aatgcagctc gtccaggaat
    17101 ttttaccgct gttatttttg gaatggcgag agcttttgga gaagccttgg ctatccaaat
    17161 ggtagtcggt aactctgctg taatgccaag ttcactaacg acaccagccg caaccttaac
    17221 gtctgtcttg acaatgggta ttggtaacac ggttatggga acggtccaaa ataatgtgct
    17281 ttggtccctt gccctagtct tattattaat gagtctggcc ttcaattccc ttgtcaaatt
    17341 aatcacgaaa gaaagaaaga gaaattatga acgctaaaaa agtcgataaa gtagcaactg
    17401 gtactcttta taccattgct ggaattattg tagctatttt agcttcctta attctatata
    17461 tccttgtccg tggcttgcca cacatcagct ggtccttttt aacaggaaaa tcgtcttcgt
    17521 acgaagctgg tgggggaatt ggtatccagt tgtataattc cttcttccta ttgattgtta
    17581 ccctgattat ttccattcct ttatcaactg gagcggggat ttacttggct gaatatgcca
    17641 aaaaagggcc tgttaccaac tttattagaa cctgtattga gattctgtct tccctaccat
    17701 ctgtggttgt agggctcttt ggttacttga ttttcgttgt gcagtttgaa tatggctttt
    17761 ctattatttc aggggctctt gctttgacgg tctttaatct tcctcaaatg acccgtaatg
    17821 ttgaagatag tttactgcat gttcatcata cccaaagaga agcaggatta gctttaggcc
    17881 tgtcacgctg ggaaacagtt ttttatgtgg ttatcccaga agctctcccg ggaatggtaa
    17941 caggtattgt cttagcttca ggtcgtattt ttggtgaagc ggcagcgctt atctatactg
    18001 ctggtcaatc agcaccagct ctggattggt caaattggaa tccacttagt gttactagtc
    18061 caatctctat tttccgtcaa tctgagaccc ttgctgttca tatttggaaa gtcaatagcg
    18121 aagggacaat tccagatgct actcttgtat ccgcaggaag tgcagcagtg ctattaattt
    18181 ttatccttat tttcaacttt tcagctcgct ttattgggaa gaaacttcat tctaaaatga
    18241 cagcagcgaa ataagatatt ggagaaatca tgacagaata taattggaat gaacgtcata
    18301 tcatcacttt tcctgaagaa acgcttgctc tagctaccaa ggatttacat gtttactatg
    18361 gtgcgaaaga agctatcaaa gggattgata tgcagtttga aaaacataaa ataacagcct
    18421 tgattggtcc atctggttgt ggcaaatcaa cttatcttcg tagtcttaac cgcatgaacg
    18481 ataccattga tattgctcgg gttacaggtg agattcttta tcagggcatt gatgttaatc
    18541 gaaaagacat gaatgtttac gagattcgca agcacttagg aatggttttt caaagaccca
    18601 atcctttcgc taaatccatt tataaaaaca ttacctttgc ccatgaaaga gctggtgtga
    18661 aagacaaaaa agttttagat gaaattgttg agacttcact gaaacaagcc gcgctttggg
    18721 atcaagttaa agatgacctt cacaaatcag ccttcacctt atcagggggt cagcaacaac
    18781 gcttgtgtat tgctagagcc atttctgtca aacctgatat tctattaatg gatgaaccag
    18841 cctctgccct tgacccgatt gcaacgatgc agctggaaga aaccatgttt gaattgaaga
    18901 agaattacac gattattatt gtgacccaca atatgcaaca agcagctcgt gccagtgatt
    18961 acactgcctt cttctattta ggcaacctca ttgaatatga taagacacgt aatattttcc
    19021 aaaatgcgca atgtcagtca acaaacgact acgtttcagg gcactttggt tagaaaggca
    19081 atatgatgac agaacctatt ttacagatca gagacctttc tgtttactac aatcaaaaga
    19141 aaacgttaaa agatgtctct ttggaccttt atccaaatga aataacagct ttaattggtc
    19201 cttctggatc tgggaaatca accctcttgc gttctatcaa ccgtatgaat gatttgaatc
    19261 ctgaagtaac cattacaggc tctatcgtct ataacggaca caatatttat agtccaagga
    19321 cagatacggt tgatctacgc aaagaaattg gtatggtatt ccaacaaccc aacccatttc
    19381 cgatgtctat ttatgagaac gtggtttacg gccttcgctt aaaaggtatc agagataaat
    19441 caatcttaga ccatgctgtt gaaagctctc ttaaaggggc ttccatttgg aatgaagtca
    19501 aagatcgttt acatgattct gcggttggct tatcaggcgg acagcaacag agagtttgca
    19561 tagctagagt tcttgctacc agccccagaa taatcctttt agatgaacct acctcagctc
    19621 ttgatcctat ctcagctggg aaaattgaag aaacattatt gttattaaaa aaagattata
    19681 cactggctat tgtgacccgc tcaatgcagc aagcctcacg tttatcagat cgaacaggtt
    19741 ttttcttgga gggtgactta cttgagtgtg gtcctacaaa agctatgttt atgaatccta
    19801 agcgcaaaga aaccgaagac tatatttctg gtaaatttgg ttgagaaaga cgtatatggt
    19861 tgacccctct gtgtttttat tataatgact agattgtagg aagaaaaaat catgttaaga
    19921 acgaaatttg aagaagaatt agataaattg cataaccagt tttattcaat gggaacggaa
    19981 gtattggcac aaatcaataa aactgttcgt gcctttgtta gtcatgatcg tgaattggcc
    20041 aaagaagtta tcgaagaaga tgacactatt aataattttg agacaaagct tgaaaagaaa
    20101 tcgctggaaa ttattgccct acaacagcca gtttcgaatg atcttagaat ggttattact
    20161 gttttaaagg catcaagtga tattgaacgt atgggtgacc atgctgcttc gattgccaag
    20221 gccactattc gtatgaaagg tgaggagcgt attccagttg ttgaagaaca aatcaacctt
    20281 atgggaaaag ctgtgaaaca gatggtagaa gaagccctta atgcatatat caatgctgac
    20341 gatacaaaag cttatgaaat cgcagcttct gatgagatta tcgatcaata tttccgtaat
    20401 atccaaacct tagctgttga agaaatccgt aagtctccag atgctgtttt tgcaggaaaa
    20461 gaatattttc aagtattaat gtatttggaa cgtattggtg actatgctcg caacatttgt
    20521 gaatggattg tttatcttaa aactggaaaa attattgaat tataagaaat tatgctataa
    20581 tgagactggg aaacagcttg ccagtccctg gttttatacg aaattgtgca agttagaaaa
    20641 tgaactaaca agaaaagttt tctttgctga atctgatttt gttaggttaa caaatatatg
    20701 tagacagaga tgatacttag gtatcatctg ttgatctatt atgatttgtt attagaatta
    20761 aggagttata tgaagacagt agaacatctc atcgaaacat ttgtgcctga aaattataac
    20821 atctttttag atattaatcg tcagactaaa acatttacgg ggaatgttgc gattaatggt
    20881 gaagctttag ataatcatgt ggctttccac caaaaagatt tggacattaa gtctattttg
    20941 ctcgataatg aagctgttat ttatcaagtg gataacgaca atgaagttgt gcgtgttgaa
    21001 ttacctgaaa caggaatgat gacgcttgtc attgaatttt caggtagcat tacagataat
    21061 atgacaggta tttacccttc atattacact aaaaatggtg agaaaaaaga agtcatttca
    21121 actcagtttg aaagccattt tgcacgtgaa gctttcccat gtatcgatga accacaagca
    21181 aaagctactt ttgatttaag cttgaccttt gatcaagaaa ttggtgagat agcgttatcg
    21241 aatatgccag aagtcaatat tgaccgtcgc gaggagactg gtctttggac atttgatacg
    21301 acaccaagaa tgtcatctta cttgctagcg tttgcgctag gagaacttca tggaaagact
    21361 gtagaaagca aaaaaggaac aactgttggt gtgtatgcga caacagcgca tcctcttagc
    21421 tcgcttgatt tttcattgga tattgcagtt cgtgttatca acttttatga agactatttt
    21481 ggagtacatt acccaatccc gcaatctctt aatattgcgc ttccagattt ttcatctggt
    21541 gctatggaaa attggggttt aatcacttat cgtgaaattt atttattagt agatgaaaat
    21601 tcgactgttc aaagccgaca acaagttgca cttgtaatcg cccacgagat agcacaccaa
    21661 tggtttggaa acttggttac aatgaaatgg tgggacgatc tgtggttaaa tgagagtttt
    21721 gccaacatga tggaatatgt ctctatcgag gctattgagc cgtcttggaa aataatagaa
    21781 gatttccaaa caggcggtat tcctcttgct ttaaaacgtg atgctactga tggtgttcaa
    21841 tcagtgcatg ttgaagtcaa tcatccagat gagataaata cattgtttga tcctgctatt
    21901 gtctatgcaa aaggtagtcg tttgatgcat atgttacgcc gttttattgg tgatcgtgat
    21961 tttgccattg gcttacatca ctactttgaa aaatatcaat atcgaaatac tgtcgggcgt
    22021 gatttatgga atattttatc agatacttca ggcaaagacg tagctgcttt tatggatgct
    22081 tggcttgaac aaccaggtta tccagtttta acagctcgcc ttgaaaacga tcaattgatt
    22141 ttgagtcaaa aacaattttt tattggaaaa ggtgaagaaa aaggtcgcct ttggccgatt
    22201 cctttaaaca ctaattggca tggccttcct gaaactttga cagaggcaga aatggtcatt
    22261 ccaaacttta gtcaattggc agcagaaaat gaaggagctc tacgtttcaa tattgataat
    22321 acagctcatt acattacaga ttaccaagga tcattattag atgccttagt cactgaactt
    22381 gcccaacttg ataatacttc tgctttacaa gttattcaag aacgtcgttt attggcagat
    22441 agtggcttga tttcctatgc tgaattggtt gacttaattg ctcaattgga cgattctaag
    22501 tcttatatgg tagcagaagc ggttcagcaa gtggtctctg gtttgaaacg cttcattgat
    22561 gaaggaagct tagcagaaaa atcctttaat cgcttggtaa ccaccatcta tcaagaagac
    22621 tttaatcagc atggttttga gaaaaaagct gacgaatcag atgaagatga gatggtacgt
    22681 caggttgcct tgggacgctt gtggctagca gaaaatcaga cgattattga cggattgaga
    22741 actatttttg aagcatatca aaacaatatt gcaagtattc cagcagctgt tcgtcgcttg
    22801 gttttagcca accaaatgaa atattttgaa acagatagct tggttgatat ttattttgag
    22861 acttatgtag caactactga taataattta cgcagtgatt taacggttgc ttttagtcaa
    22921 acaaaacaat caactactat tagacgtatt cttgttagtt taaaagataa agatattatt
    22981 aaacctcagg atttatctta ttggtacaat gctttgcttg gacaaagctt tactcaagat
    23041 atcatttggg aatgggctag agaaaattgg gattggatta aatctgcact tggtggagat
    23101 atgagctttg ataaatttgt tatttatcca gcaagtaact ttaaaacacc aaaacatcta
    23161 gcagaatata aatctttctt tgaacctaag ctagatgata tggctattag ccgtaatatt
    23221 accatgggaa ttaatgaaat tgaagcacgt gttgctttga tcactaaaga aaaagaagca
    23281 gttattgcag ctctcagtca ttactagacc ataagcaaaa gagttggggg gactttccag
    23341 ctcttttttg tagtgagcta gcttcctttc ttagttccgt ctataactaa atgattatcc
    23401 atagtttaat tcaaaaggag attgcacttt aaagcgaagg ctattagcct cttaaatact
    23461 tttttaccag gtggtgaata agaacaatta taaatgattt aatcattatg ctttaaatgc
    23521 cttaaaggag tattaatatt ttagtaaacc ttaagctttt tgtagtatag tctcgttaga
    23581 aattgttatc agaaatgaga ctaagttaaa tgaagtgata gttactttat ttaagaacaa
    23641 ttgaggtaga gacatgataa aaatattatt agtagaagat gacttgagct tatcaaattc
    23701 catttttgat tttttagatg attttgcaga cgtcatgcaa gtttttgatg gcgatgaagg
    23761 tttatacgaa gcagaaagtg gtatttatga tttgattttg ttagacctta tgttgccgga
    23821 gaaaaatggc tttcaagtct taaaagaatt gcgagaaaaa gatattaaaa ttcctgtgtt
    23881 gatcatgaca gctaaagagg gtttagatga taaaggtcac ggatttgaat taggtgctga
    23941 tgattatctg acaaagccgt tctatttaga agagttaaaa atgcgaattc aagcactgtt
    24001 aaaaagaaca gggaaatttg cagataaaaa tattagtttt ggcaatttag tggtcgactt
    24061 agctcgaaaa gaggtgaagg ttgaagggaa agtagttgaa ttacttggca aagaatttga
    24121 tttgttggtg tatcttttgc aaaatcaaaa cgttatttta ccaaagacac aaatttttga
    24181 tcgtttatgg ggattcgata gtgatactac gatttcggtt gttgaagttt acatttctaa
    24241 aataaggaaa aaattaaaag gtacccgttt tgttaacagg cttcaaactt taagaagcgt
    24301 aggatatatt ctaaaaaaca atgaataaat taaaaaaaga gattttatca gataactata
    24361 accacttttt tcattttttt gcggttttta caggtatttt tgtcattatg actattatta
    24421 tcttacagat tatgcggttt ggcgtttatt cgtcagttga cagtagttta gtttctgtta
    24481 gtaataatgc aagtagctat gctaatcgta cgatggctag aatatcttct ttttactttg
    24541 atactgaaaa taacattatt aaggcgctgc ctgattcaga tagttctaag ttattaggaa
    24601 cgcctgcagc taatacagat atcattttgt ttagtgctaa tggaacaatt ttaaatgctt
    24661 ttgatgcgtt ttctaactat caaaattttc atttagataa acgccggttg gggagtattg
    24721 aaaccaccag tttaatgaat ttttatggac aagaagaaaa ataccatacg ataactgtaa
    24781 gggttcatat caaaaattat cctgcagttg cctatatgat ggcagtagta aatgtggaac
    24841 aattagaccg cgctaatgaa cgttatgagc gcattattat tatagttatg agtgtttttt
    24901 ggctaatttc tattttagca agtatttatt tagccaagtg gagcagaaaa cctattttag
    24961 aaagctatga aaaacaaaaa atgtttgttg aaaatgctag tcatgaacta aggacccctt
    25021 tggcggtctt acagaatcgt ctggaatcgc tttttcgtaa gcccaacgaa acgatattag
    25081 aaaatagtga gcatctcgct tctagtttag acgaggttcg caacatgcgc atcttaacaa
    25141 ctaatttatt aaatttagca agacgagatg atggcattaa tccacagtgg actcatttag
    25201 atacagattt ttttaatgct atttttgaga attatgaact agttgctaaa gaatatggaa
    25261 aaatatttta ttttcagaac caagtcaata gatcgttaag aatggataag gctttactaa
    25321 aacaattaat aacgatttta tttgacaatg ctattaaata tacagataaa aatggtatta
    25381 ttga
//
LOCUS       DAUCXI010000025        25377 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.025, whole genome shotgun sequence.
ACCESSION   DAUCXI010000025 DAUCXI010000000
VERSION     DAUCXI010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25377
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.025"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(537..923)
                     /gene="rplQ"
                     /locus_tag="VGY43_001106"
     CDS             complement(537..923)
                     /gene="rplQ"
                     /locus_tag="VGY43_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEQ4302296.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYIRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(938..1876)
                     /locus_tag="VGY43_001107"
     CDS             complement(938..1876)
                     /locus_tag="VGY43_001107"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEQ4302297.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1922..2305)
                     /gene="rpsK"
                     /locus_tag="VGY43_001108"
     CDS             complement(1922..2305)
                     /gene="rpsK"
                     /locus_tag="VGY43_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEQ4302298.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2323..2688)
                     /gene="rpsM"
                     /locus_tag="VGY43_001109"
     CDS             complement(2323..2688)
                     /gene="rpsM"
                     /locus_tag="VGY43_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEQ4302299.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2706..2822)
                     /gene="rpmJ"
                     /locus_tag="VGY43_001110"
     CDS             complement(2706..2822)
                     /gene="rpmJ"
                     /locus_tag="VGY43_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEQ4302300.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2848..3066)
                     /gene="infA"
                     /locus_tag="VGY43_001111"
     CDS             complement(2848..3066)
                     /gene="infA"
                     /locus_tag="VGY43_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEQ4302301.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3184..3822)
                     /locus_tag="VGY43_001112"
     CDS             complement(3184..3822)
                     /locus_tag="VGY43_001112"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEQ4302302.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3972..5276)
                     /gene="secY"
                     /locus_tag="VGY43_001113"
     CDS             complement(3972..5276)
                     /gene="secY"
                     /locus_tag="VGY43_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEQ4302303.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5293..5733)
                     /gene="rplO"
                     /locus_tag="VGY43_001114"
     CDS             complement(5293..5733)
                     /gene="rplO"
                     /locus_tag="VGY43_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEQ4302304.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5948..6130)
                     /gene="rpmD"
                     /locus_tag="VGY43_001115"
     CDS             complement(5948..6130)
                     /gene="rpmD"
                     /locus_tag="VGY43_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEQ4302305.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            complement(6145..6639)
                     /gene="rpsE"
                     /locus_tag="VGY43_001116"
     CDS             complement(6145..6639)
                     /gene="rpsE"
                     /locus_tag="VGY43_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEQ4302306.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6658..7014)
                     /gene="rplR"
                     /locus_tag="VGY43_001117"
     CDS             complement(6658..7014)
                     /gene="rplR"
                     /locus_tag="VGY43_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEQ4302307.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7119..7655)
                     /gene="rplF"
                     /locus_tag="VGY43_001118"
     CDS             complement(7119..7655)
                     /gene="rplF"
                     /locus_tag="VGY43_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEQ4302308.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7858..8256)
                     /gene="rpsH"
                     /locus_tag="VGY43_001119"
     CDS             complement(7858..8256)
                     /gene="rpsH"
                     /locus_tag="VGY43_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEQ4302309.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8407..8592)
                     /locus_tag="VGY43_001120"
     CDS             complement(8407..8592)
                     /locus_tag="VGY43_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEQ4302310.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8608..9150)
                     /gene="rplE"
                     /locus_tag="VGY43_001121"
     CDS             complement(8608..9150)
                     /gene="rplE"
                     /locus_tag="VGY43_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEQ4302311.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9174..9479)
                     /gene="rplX"
                     /locus_tag="VGY43_001122"
     CDS             complement(9174..9479)
                     /gene="rplX"
                     /locus_tag="VGY43_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEQ4302312.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9558..9926)
                     /gene="rplN"
                     /locus_tag="VGY43_001123"
     CDS             complement(9558..9926)
                     /gene="rplN"
                     /locus_tag="VGY43_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEQ4302313.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9951..10211)
                     /gene="rpsQ"
                     /locus_tag="VGY43_001124"
     CDS             complement(9951..10211)
                     /gene="rpsQ"
                     /locus_tag="VGY43_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEQ4302314.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            complement(10237..10443)
                     /locus_tag="VGY43_001125"
     CDS             complement(10237..10443)
                     /locus_tag="VGY43_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEQ4302315.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10453..10866)
                     /gene="rplP"
                     /locus_tag="VGY43_001126"
     CDS             complement(10453..10866)
                     /gene="rplP"
                     /locus_tag="VGY43_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEQ4302316.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10870..11523)
                     /gene="rpsC"
                     /locus_tag="VGY43_001127"
     CDS             complement(10870..11523)
                     /gene="rpsC"
                     /locus_tag="VGY43_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEQ4302317.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11536..11880)
                     /gene="rplV"
                     /locus_tag="VGY43_001128"
     CDS             complement(11536..11880)
                     /gene="rplV"
                     /locus_tag="VGY43_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEQ4302318.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11896..12174)
                     /gene="rpsS"
                     /locus_tag="VGY43_001129"
     CDS             complement(11896..12174)
                     /gene="rpsS"
                     /locus_tag="VGY43_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEQ4302319.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12313..13146)
                     /gene="rplB"
                     /locus_tag="VGY43_001130"
     CDS             complement(12313..13146)
                     /gene="rplB"
                     /locus_tag="VGY43_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEQ4302320.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13164..13460)
                     /locus_tag="VGY43_001131"
     CDS             complement(13164..13460)
                     /locus_tag="VGY43_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEQ4302321.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13460..14083)
                     /gene="rplD"
                     /locus_tag="VGY43_001132"
     CDS             complement(13460..14083)
                     /gene="rplD"
                     /locus_tag="VGY43_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEQ4302322.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14107..14733)
                     /gene="rplC"
                     /locus_tag="VGY43_001133"
     CDS             complement(14107..14733)
                     /gene="rplC"
                     /locus_tag="VGY43_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEQ4302323.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14981..15289)
                     /gene="rpsJ"
                     /locus_tag="VGY43_001134"
     CDS             complement(14981..15289)
                     /gene="rpsJ"
                     /locus_tag="VGY43_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEQ4302324.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15488..16777)
                     /locus_tag="VGY43_001135"
     CDS             complement(15488..16777)
                     /locus_tag="VGY43_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEQ4302325.1"
                     /translation="MIYNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLVAVSGV
                     SIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLL
                     SVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQV
                     SLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGMFLLCQFIPIKQVVKRLMRPL
                     DKIIFDLSLPAAGERLMMRAGDVLIIGIVVRFGTTALAGNAIGETLTQFNYMPGLAMA
                     TATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDA
                     QRSAMVVLLFSLLGAPATAGTLVYTAVWQGLGKAKFPFYATTIGMWVIRIGLGYVIGV
                     VWQYGLIGVWMATVLDNTSRWFILSKQFKKYQEITSH"
     gene            complement(17165..18181)
                     /gene="adhP"
                     /locus_tag="VGY43_001136"
     CDS             complement(17165..18181)
                     /gene="adhP"
                     /locus_tag="VGY43_001136"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEQ4302326.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPNVGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18433..21075)
                     /gene="adhE"
                     /locus_tag="VGY43_001137"
                     /gene_synonym="adhC"
     CDS             complement(18433..21075)
                     /gene="adhE"
                     /locus_tag="VGY43_001137"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEQ4302327.1"
                     /translation="MTEGHNTVETTSVSVTIDALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKTADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
     gene            complement(21384..23159)
                     /locus_tag="VGY43_001138"
     CDS             complement(21384..23159)
                     /locus_tag="VGY43_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEQ4302328.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLFWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNFSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMVGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGTLALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSKIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPNGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVEHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
     gene            complement(23156..23557)
                     /locus_tag="VGY43_001139"
     CDS             complement(23156..23557)
                     /locus_tag="VGY43_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302329.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRIHYTGYVINHKMNGEGKLVYPNGDIYEGTFKNGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            complement(23580..24017)
                     /locus_tag="VGY43_001140"
     CDS             complement(23580..24017)
                     /locus_tag="VGY43_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEQ4302330.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY"
     gene            complement(24155..25153)
                     /gene="ruvB"
                     /locus_tag="VGY43_001141"
     CDS             complement(24155..25153)
                     /gene="ruvB"
                     /locus_tag="VGY43_001141"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEQ4302331.1"
                     /translation="MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            complement(25184..25282)
                     /locus_tag="VGY43_001142"
                     /pseudo
     CDS             complement(25184..25282)
                     /locus_tag="VGY43_001142"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
BASE COUNT         7514 a         5344 c         4455 g         8064 t
ORIGIN      
        1 gtactttttt acaattttgt tggaaacggc ttaaagtgac agattttaaa agtaaaaaag
       61 atattttcac ctccaaatta aaagaggatt ttaaaatact tattaataaa atattgaata
      121 ggagataaaa ctaacaatat agtttgagca tctgtttgcg atgcaagttt ttttcggaca
      181 tttaaatgag ggggttacac cgtttatttg cccatgagag gtctttaaac acctgcataa
      241 ggttttctta ttctaatgac cttattgtct ctgagaaaac tttataaacg catcagaaga
      301 ggcttctgtg ttattgtttt gctcagctta aaagcggggg ggtcacctca taatacaaca
      361 aaacgcctgc ttataaaaag tttctatagc ttagatacct ttcataaaca agcgttacat
      421 attaacaata tgatgagtgt tcccgctagg aaaaatccta gcggtagacc agagctagac
      481 taagaataat ctctcgatta ctccatcatc ataacactca acaaaattga taaaaattaa
      541 actaattcaa taattgccat tggagcagca tctccacggc gtggttctgt tttaagaata
      601 cgagtgtatc caccgttacg ttctgcataa cgaggtgcaa tttctgagaa aagtttttga
      661 agagctgtcg ttgatgtgta tttatcggta gcttcatcat aattttctga tgcgatttcg
      721 ttacgaatgt atgcagctgc ttggcgacga gcatgaagat caccacgttt accaagagta
      781 atcatttttt caactgtttt acggatttct tttgcacgtg cttctgtcgt tacaattgat
      841 tcgttgatca aaagatctgt cgtcaaatca cgaagcattg ctttacgttg tgagctagtg
      901 cgtcctagtt tacggtaagc cattttgtcc tcctatatta tttatcgttt tttagtccga
      961 gacctaagtc agcaagttta accttaactt cttcaaggct cttacgtcca agattacgga
     1021 ctttcatcat ttcaggctca gatttttctg ttaagtcgaa gacagtgtta atgcctgcac
     1081 gttttaaaca gttatatgag cgtacggata aatcaagctc ctcgatggtg cggtcaagta
     1141 ccttttcatc gttcactttt tcagtttctt tcattacttc ggtagctttt gcaacctctg
     1201 ttaaatcagt aaacaggttt aagtgttcga tcaaaactcg agcagataga cctaaagcat
     1261 cttcaggaat aattgttccg tttgtcatga tttcaatcgt taatttatca aagccatcat
     1321 tgctacctac acgggcaggt tcaacttgat aattaacttt tttaactggc gtatagattg
     1381 aatctactgc caatgtaccc acaggtgcat catctttttt gttgccttct gctggcacat
     1441 aaccacgttt tttagcaaca gtcattgttg cacgtagaga atgtccttca gcgattgtaa
     1501 aaagataatg atccgggtta acaagttcga tatcactgtc agtaagaata tcaccagctg
     1561 ttacctctgc tggtccttct acttcaagtt cgataatctt ttcgtcttcg acgtatgatt
     1621 tcacagcaag tcccttaaca ttaaggataa tttgcatgac atcttcacgt acacctggga
     1681 ttgtatcaaa ttcgtgtagt actccatcaa ttttaattga tgttactgct gcacctggaa
     1741 gtgaagacaa gagtacacga cgaagagaat tacctagagt tgttccgtag ccacgttcaa
     1801 gtggttcgat gacaaatcta ccgtaatctt tattttcatc aatttttgtt attattggtt
     1861 tttcaaactc aatcattttt tcacccctcg aaacgaaact tgtgtactat ttgttatatg
     1921 attatacacg acgacgtttt ggaggacgag caccattatg tggcacaggg gtcacatcac
     1981 gaattgcagt tacttcaaga cctgcagctg ctagagcacg aatagctgat tcacgacctg
     2041 aaccaggacc ttttacagtc acttcaacag tttttagtcc gtgttcttgt gcagattttg
     2101 cagctgcttc tgcagccatt tgagcagcaa atggagtaga tttacgagaa cctttgaaac
     2161 caagagcacc agctgatgac catgcaagag cattaccatg cacatctgta atcataacaa
     2221 tagtgttatt aaatgtagcg tgaatgtgtg caacaccaga ttcgatgttc tttttcacac
     2281 gacgtttacg tgttggttta gccaattgtt ttacctccta ttttattttt tcttacctgc
     2341 aatcgcaaca gctttccctt tacgagtgcg agcattgttt ttagtatttt gtccacggac
     2401 aggaagtcca cgacgatgac ggattccacg gtatgaaccg atttccatca aacgtttaat
     2461 gttcatgttt acttcacgtc gaaggtcacc ttcaactttg attgcatcca cttcacgacg
     2521 gatagcatct tcttgatctg atgttaaatc tttaacacgg atatcttcag aaatacctgc
     2581 agctgctaag atttttttag atgttgcaag accaattccg taaacataag taagtgaaat
     2641 tactacgcgt ttatcatttg gaatatcaac tccagcaata cgagccattt tttctccttt
     2701 ctattttatc cttgacgttg tttgtgtttt ggatttgtcg gacaaattac cataacacga
     2761 ccattacggc gaataacttt acagtattcg caaattggtt taaccgatgg tcttaccttc
     2821 atgttttaat ccctccaatt atttcgatta tttaaagcgg tatgtgatgc gtccacgtgt
     2881 caagtcataa ggactcattt ctactgtaac acggtcacct actaaaatac gaatgtaatt
     2941 tttgcggatt tttcctgata cagttgctag aatttgatgt ccattttcca attcaacagt
     3001 aaacattgca tttggcatcg tttctactac tttgccttca atttcaatca cgtcttcttt
     3061 tgccacgcaa aagtaccccc taaatttcga tttgatgtcc tctgagcaca gaggtaacaa
     3121 ttataagtca gactaaacta gtatatcatt actaatctac ttatgcaagt agattagtat
     3181 aatttatttg agttctagca acgctttttc aacatctgca aaaacgtctg ttatttcttg
     3241 attaccttca atatctgtaa caagaccaag cttacgatag tgttcaagaa taggttctcc
     3301 ttgagccata ttgacgtcca aacgacgttt aacagtttca ggcttatcat cttcacgttg
     3361 atagtaatct tcttctttat aatctactgg tgggttgaac actttatgga acgtttcacc
     3421 agttttacga ttgataatac gaccactcaa acgctctaca agacatgatg gatccacttt
     3481 aatattaata acaccatcta agcggagtcc tagttcttca agtgttgcat ctaaggcgtg
     3541 tgcttgttca atagtacgtg gatacccatc aagcaaaaaa cctttttctg cgatatcatc
     3601 ctcagctaag cgctctttta caatcccgtt tgtgacttca tcaggaacca attcaccttt
     3661 atcaatataa cttttagcta aacgtcccat ttcggtttga ttagccattg cggcgcggaa
     3721 catatccccc gttgagatgt gagcaacacc aaattcttca acaatcttag ctgcttgggt
     3781 ccctttacca gctcccggca aacccatgat taaaagattc atcttttcct cctcttttaa
     3841 aataaataca tagtaggaaa ttattttcct tggtttttgt tttcaaatgg caacaagaaa
     3901 tcgtttgatg ataaccaagt cttattgtca tttaaaaaca aaatagaagg ttgacaatgt
     3961 caacctgtat tctattctgc tgtattcata aatccgacat attttctctt tagaagatat
     4021 ccctcaagct gtttcatacc ttcgatacca gttgaaatca aaatgagcaa actagttcca
     4081 cctaaagcaa tactagaaga aaggttgaga gcttgttgtg ctgctattgg cgctaaagag
     4141 ataaatgcta agaagatagc tcctacggtt gctagttttt ttagcaatgc ggacataaat
     4201 tgttctgtct cacgtccagg gcgaacactt ggtatatatg aggaattctt ctgaagattt
     4261 tctgctgtct tctcaggatt aacttgtaca aaggtataga agaatgagaa caatataatc
     4321 aacaaggcgt aaactatcat tccgactgga gtttgataat taaaaatttc ttgcaaacgg
     4381 tttaaccacg gtaaatctct accattttga acaaaaggaa taatcgtact tgggatagtt
     4441 gtaatcgagc tagcaaagat aacgggaata acgccggctg gatttacttt taatggaaga
     4501 tatgaacttg taggtgcacc ttgcattagc tttgtgtatt ggattggaat tttatattcc
     4561 gcttgttgga catatgttgt aaagaaaaca atagcaagaa cagctatgat taaaatccca
     4621 acaatgagat aagacgagtg taaatcactt gccttaacat ttacaaaata gtcttcacga
     4681 attgttgcaa ttgcacttgg aatagacgaa ataatacccg caaagataat cattgatacg
     4741 ccattaccaa atcctttatc tgtgatttgt tctccaagcc aggtaacaat aacgctacct
     4801 gttgtcagta atgccccgat cagtaaatat gttttgatgt ctggtgtctt aacaagtgca
     4861 acgttcgaca aagtattaaa ccctgcagtg ataccaatgg attgggcaaa agccaaaaca
     4921 agtgaaatat agcgcgtcgc ttgatttaat ttacgacgtc caacctcacc ttgtttgccc
     4981 cactcaacaa acttaggtaa aatatccatc tgcaataact gaacaacgat agaagcagta
     5041 atatatgggc taacccccat tgaaaatact gagaaatttc tcatcgcatt accactaact
     5101 aagtttaaca tatttaagaa agggagttca cttaattgct ctaagctctt ggcatttaca
     5161 ccaggtacgg taatatgtgt cccaattcgg aatacaagaa tgataaatat agtaaagaaa
     5221 attttattcc gtacagtctt tatctttaac gcgtctttta gtatttttaa gaacataatg
     5281 agtatcccct cattagatga cttcgattga accaccttta gcaataatag ctgcttcagc
     5341 agattttgag aacttagctg cttttacagt caatttttta gtcaattcac cgttaccaag
     5401 cactttaacg cctgattttt cagctcggac aataccagca tcttttaaaa tagccggagt
     5461 cacttctgta ccatcatcaa aaacattcag ttgatcaaga ttcacaagtg catattcttt
     5521 agtattaata tttgtaaagc cacgttttgg aatacgacgg aacaatggtg tttgtccacc
     5581 ttcaaaacct aaacgtacac cgccaccgct acgagctttt tgaccttttt gaccgcgacc
     5641 agatgtttta ccattacctg atgatgtccc acgaccaaca cggttacgta ctttacgtga
     5701 gccttcagca gcttttaatt catgaagttt cattttttct cctttttttg taaaatgcta
     5761 gcgcctctat gagggaaaag gactccctat agaaactcgc ctatacatta atgatactta
     5821 agttatccaa aataacttaa tacagatacg cactaaccga ctactgtttg ttgccaaaaa
     5881 agcaaactac aagagtcggt tttgtgctcg tttttaatta tgaaatcaga gatttcacag
     5941 ttataactta tttaacatct tcaacggtaa ccaagtgaga aatagctgtc accataccac
     6001 ggatagcagc attatcttct ttgactactg aagagtttaa tttaccaagt ccaagagcaa
     6061 caacagtttt acgttgttct ggcttacgtc cgataggaga cttagtcaaa gtaattttaa
     6121 tttgagccat gatgatcccc tttcttatgc taagtcagaa actgagatgc cacgaagtgc
     6181 ggcaacttct tctgcacgtt taagttgttt caatccttca acagttgcac gaacaatgtt
     6241 gattggagtg tttgaaccaa gagattttga agtaatatca gcaacacctg ctaattcgat
     6301 gacggcacga actgcaccac cagcagcaac tccagaacct tctacagctg gtttcaataa
     6361 tactttagct ccaccgaagt tagtgtaaac ttcgtgaggg attgttgtac caaccattgg
     6421 tacttcgatc atgtttttct tagcagcttc aactgcttta cggatagctt ctggaacttc
     6481 ttgagcttta ccagtaccaa atccaacacg accatttcca tcaccaacaa ctacaagagc
     6541 tgcaaagcga agacgacgtc cacctttaac aacttttgta acgcggttaa tcgcaacaac
     6601 gcgttcttca agttcaactg cattatcttt aaatgccatt attttgtgtc ctccctatta
     6661 gaatttcaat ccgttttcac gagctgcatc agccaaggct ttaacacgtc cgtgatagag
     6721 atatccaccg cggtcaaaca ccacttcaga aataccttta gccactgcac gttcagcaac
     6781 aagtttgccg actacaacgg cttgttctgt ttttgttcct ttagaaacgt ctttatcaag
     6841 agttgatgca cttgcgagcg ttacacccgc tacgtcatca ataacttgag cgtagatgcc
     6901 tgtattagaa cggaatacgt tcaaacgtgg gcgatcagca gttccagaga gtttaccgcg
     6961 gacgcgacgg tggcgttttt ggcggatttt gtttttatct ggtttcgaaa tcacaatttt
     7021 cacctcttaa ttttaatcaa tttgtctcat tgacaagttg tcgattgaac ttatcgagca
     7081 tgttaaggtg caatacttcc catacccgac taagaacatt atttacctgt tttaccttct
     7141 ttaaggcgta cgtattcacc aacgtaacgg atccctttgc ctttgtaagg ctctggtgaa
     7201 cgcaagctac ggatgtaagc agctgtttga ccaacaactt ctttgttgat tccttcaact
     7261 gagattgaag ttgggttagc aacagtgaaa gtaattcctt ctggagcttc aacttcgtct
     7321 tggtgagatt tacctactga aaggacaagt ttagtacctt gaagttgagc acggtaaccg
     7381 acacccttca tttcaagatc ttttttgaaa ccttcagaaa cacctacaac catgttattc
     7441 aagttagcac gggttgtccc atggattgtt ttcatttctt ttgagtcgtt aggacgtaca
     7501 actgtgattt cagtcccttc aactttgatt tcaatatttt tgttgaactc acgagtgagt
     7561 tcgcctttag ggcctttaac agtaataaca ttgttgttat ttgttaattc aacgcctgca
     7621 ggcatagtaa ttactttatt accaatacgt gacatgttta ttttctcctg ttaaattgtc
     7681 aagccgcata gcgactagtt ttcacggggg tttgatagaa tgatatactt caatttatat
     7741 ttcaaaattg aacacgagct gtggtctgtg tgaaaaagat aaatcttcct tgagtgtaaa
     7801 cacgctacgt cagatttcct attttcactt tgtccacgac gctcttagta tcttaaatta
     7861 ccaaacgtaa gcgatcactt ctccaccaac attcttttgg cgagcttctt tgtcagtcaa
     7921 aagaccttct gatgttgaaa tgattgcaat tccaagtccg ttaagaactt taggcatgtc
     7981 atcacgtttt gcgtaaacgc gaagacctgg ttttgaaata cgttttaagt tagtgataac
     8041 acgctcacca ttttttccgt attttaagaa cacacgaatg atgccttgtt tatcatcttc
     8101 gataacttca acatttttta caaaaccttc acgtttaaga atctcagcaa tccctttttt
     8161 aatgtttgaa gcaggtactt ctaacacttc gtgttttact tgattagcat tacggatacg
     8221 tgttaaaaag tctgcaattg ggtcagtcat aaccattttt tatattctcc tcttactagc
     8281 agtttgatgc tatcacttac tagttaatgt tgtccttaaa ggactttggt atcagcttat
     8341 gctcacaccg ttttaattaa gcacaagact taatctgaag aacaaattaa gttttgtgtc
     8401 atatttttac caagaagctt tgacaacacc tggaatttga cctttgtaag ccaattcacg
     8461 gaagcaaaca cgacaaagtt taaacttgcg gtaaactgaa tgtggacgtc cacatttttc
     8521 acagcgagta taagcttgtg tagagtgttt tgcaggacgt ttgttcttag caatcataga
     8581 ttttttagcc aatttattta ccccctatta ttttgcaaaa ggcattccaa ggcccttaag
     8641 caattcacgt gattcttcgt cagtatttgc agtagtgacg attacaatat caagaccacg
     8701 tactttatca acatcatcaa agctgatttc tgggaagata agttgttctt tcacaccgag
     8761 agtgtagttt ccgcgtccat caaacgattt tgttggaacg ccatggaagt cacgtacacg
     8821 aggaagtgaa acgctaacca atttgtctag gaattcgtac atacgttcgc cacggagggt
     8881 aacttttgca ccgatcgcta caccttcacg aagacggaag ccagcgattg atttcttagc
     8941 tttagtaata agtggttttt gacctgagat aagtgctaat tcagctgcag ctttctctag
     9001 gttttttgcg ttggatacag catcaccaac acccatattg agaacaattt tctcaacttt
     9061 tggcacagcc ataactgatg tgtaattgaa tttctctgtc aacgcaggaa ttacttcgtt
     9121 agtatatttt tcttttaaac gatttgccat tatgcttctc ctttccttcg tgattaatca
     9181 agcacttcgc ctgatttttt gctgtaacgt acttttttac cgtcaacaac tttataacca
     9241 acacgtccag ctacaccatt tttatctaat acttgaacat tagagacatg gataggtgct
     9301 tctttttcga cgatagctcc ttgaggattt tcagtgttag gtttttggtg ttttttaatc
     9361 attccaacac cttcaacaat aactttgtta acttttggaa gtgctttaag aactacagct
     9421 tcagtgcctt tgtccttgcc agcaattacg cgaactttgt cgcctttttt tacaaacatt
     9481 ctggtttctc ctattatttc ttacgccccg atgggcaccc taggaaaacc taggggacta
     9541 cgtttgttaa cctgagatta aagtacttct ggtgcaagtg atacgatctt catgtagcca
     9601 ccctcacgca attcgcgtgc aactgggcca aagatacgag ttccgcgagg agttttatca
     9661 tcacggatga ttacagcagc attgtcgtca aatttgatgt atgaaccgtc tggacggcgt
     9721 gcaccagttt ttgtacgaac gataacagct ttaaccacat cacctttttt aactgctcca
     9781 ccaggagtag cttgttttac agaagcaacg attacgtcac cgatgttagc gaatttacgt
     9841 cctgaaccac caagtacttt gatagtcaag atctcacgag caccgctatt atcagcaact
     9901 ttcaagcgag tttcttgttg aatcatttca attttctcct tttagtttga ttagataata
     9961 acagcttttt ccactacttc cacaagacgg aaacgttttg tagctgaaag tgggcgagtt
    10021 tccatgatac gaacgatatc gccttcttta gcaacgttgt tttcgtcatg tgctttatat
    10081 tttttagaat agttgatacg tttaccatag actgggtggt tacgtttagt ttcaactaca
    10141 actgtgattg ttttgtccat cttgtcagac actacgcgtc cgtaaagagt tttacgttga
    10201 ttacgttcca tttagaattt ctcctttccc aatctattat ttcatttctg attgcacagt
    10261 tttaacacgt gcaatttgtt tcttaacttc gtcaaggcga gcagtctttt caagttgacc
    10321 tgctgcagct tggaaacgaa gatcaaacaa ttcttttttg agttcgtttt ctttcttagc
    10381 aagttcttct tgagacaatc cacgaagctc tttaacaaaa tctttaattt cttgaagttt
    10441 catgtcttct ccttattctg cttcacgttt tacgaatttg cacttaactg gtaatttgtg
    10501 gctagcaaga cgtaatgctt cgcgagcaat ttcttcagaa acaccagcaa tttcaaacat
    10561 cactttacca cgtttaactg gtgctaccca accttcaggt gcccctttac cagaacccat
    10621 acgtacaccg atagcttttg cagtgtatga tttgtgtggg aagattttaa tccaaacttt
    10681 accaccacgt ttcatgtaac gagtcatcgc aatacgggca gcttcgattt gacggtttgt
    10741 aatccagtgg ctagttgtgg cttgaagtcc gtattcaccg aatgaaactt ctttaccacc
    10801 tttagcctca ccgcgcattt ttccacggaa ttcgcgacgg tgtttaacac gtttaggtac
    10861 taacatttgt tatttgcctc ctttagtgtt tttacgagct ggaagaactt ctccacggta
    10921 aatccaaact ttaacgccaa gtttaccata agttgtgtca gcttcttccc aagcatagtc
    10981 gatatcagcg cgaagcgtgt gaagtggaac agttccttct gaataacctt cagcacgagc
    11041 gatatcagca ccgttcaaac gaccagaaac ttgagtttta atccctttag ctcctgcacg
    11101 cattgtacgt tggattgctt gtttttgagc acgacggaaa gcaacacgtt gctcaagttg
    11161 acgagcaata ttttcaccaa caaggtgagc atctaaatca ggttgtttga tttcgatgat
    11221 gttgatgtgt acttgttttc cagttaattt gttaagttga ccacgaagag cgtcaacgtt
    11281 tgcgccacct ttaccgataa ccatacctgg tttagcagtg tgaagtgaaa caataacttt
    11341 gtttactgca cgttcaattt caatagttga aactgatgcg tcagctaatt ctttattaat
    11401 gaatttacgg attgcaagat cttcatgaag gtaatccgcg tattcttttt cagcatacca
    11461 tttcgcatcc cagtcacgga tgattccgac acgcatacca attggatgta ctttttgacc
    11521 cacgatttta cctccttatt tttctgatac aactacagtt acgtgagttg tacgtttgtt
    11581 gattggtgaa gctgaacctt tcgcacgtgg acggaaacgt ttcattgttg gtccttcgtt
    11641 agcgaatgtt tcagatacta ccaagtttgc tttttccaaa ccaaagttgt tttctgcgtt
    11701 agcaattgct gagttaagag ttttctcaat aacacgagct gctttgtttg gagtgaattt
    11761 taagattgcg attgcgtcag caactttctt accacggata agatcaagta ctaaacgtgt
    11821 tttacgaggt gaaacacgca ctgtacgagc cattgcttta gctgaagtaa tttctgccat
    11881 tgtgtcctcc tcctattaac gacgtgtttt cttgtcgtca gctgcgtgac ctttgtaagt
    11941 acgcgttggt gcaaattcac caagtttgtg acctaccatg tcttcttgga tgtaaacagg
    12001 tacatgttta cgtccgtcat aaactgcgat tgtatatccg atgaaacttg ggaaaatcgt
    12061 tgaacgacgt gaccaagttt tgattacttt tttcttttcg tcgtttgctt gagcttcaac
    12121 ttttttcatc aaatgctcat cgacgaaagg tcctttttta agactacgtc ccattttgta
    12181 gttttctcct ttaaataatg taccacagcg gcttgaattc aagagcaaga ctccaaactc
    12241 taccgagttg gcggaataaa tagtaaagct attgtaacgc tatttcagca agttttaagc
    12301 aacttactaa aattattttt cgttacgacg acgaacgata agtttgtctg atttagcttt
    12361 cttgttacga gttttaagac caagcgctgg tttaccccat ggagttgatg gcgctttacg
    12421 tccaactggt gctttacctt caccaccacc gtgtgggtga tcgttagggt tcattacaga
    12481 accacgaact gttgggcgga tacctttcca acgactacgt cctgctttac caatgttaac
    12541 aagtgattgt tgttcgttac caacagtacc gatagttgca cggcatgtac caagaatcat
    12601 acgaacttcg cctgattgaa gacgaacaag aacgtattta ccttcttgac caagtacttg
    12661 agcagaagct ccagctgcac gaacaagttc tccaccttta ccaggtttca actcaatatt
    12721 gtgaacaact gtaccgacag gaatgtttgc taatggaagt gcgttaccaa ctttgatgtc
    12781 ggcatctgga ccagaaacaa tacgttgacc tacttcaaga cctttaggtg caatgatgta
    12841 agctttcaca ccgtcagtgt aatgtacaag tgcgatgttt gcagtacggt ttggatcata
    12901 ttcgattgtt ttaacaactg cttcaacgcc atctttgtta cgtttgaagt cgatcaaacg
    12961 gtaatgacgt ttgtgtccac caccttggtg acgaactgtg atgcgaccat tgttgttacg
    13021 accagctttg ctcttaagag aaacaagcaa ggatttctca ggcgtgcttg ttgtgatttc
    13081 cgcgaaatcc aaagaagtca tgttacgacg gccatttgtc gttggtttat aaactttaat
    13141 acccacgtta tttcctcctt agattattca gcttcagctg cgaacaactc gattgcttta
    13201 gaatcagctg taagagtgat gatagctttt ttagtttttg aagtgaaacc tgtgtaacga
    13261 ccaacgcgtt ttgcttttgg tttaacgtta acagtattta cacttgcaac tttaactccg
    13321 tcaaaagcag cttcaacagc ttgtttgatc aaaagtttgt gtgcacgagt atcaacttcg
    13381 aaagtgtatt tacctgcttc aagagcaatc attgacttct cagtgataac tggttttttg
    13441 attacgtcgt acaaattcat tatgcaagaa cctcctcaat tgtagagatt gcttctttag
    13501 taacaagaag tttgtctgcg ttcacgatat caagaacact tgcagttgct gcagttgcaa
    13561 cagttacgtt tggaaggtta cgtgcagaaa gtgctgcaaa ttcatttcct tcttcaacaa
    13621 gaacaagtac ttttgtatca atgctaagag ctgaaagcac ttttgcaaat tcagcagttt
    13681 ttggtgctgc aaatgaaagg ccttctacag ctacaaattt atcttcagca acttttgctg
    13741 agtaaactga tttcaacgca aggcgacgaa ctttttgtgg aagtttgtat ccgtatgaac
    13801 ggggagttgg tccaaagaca acaccaccac cacgccattg tggtgagcgg atagaacctt
    13861 gacgagcgcg tccagttcct ttttgacgcc atggtttacg tccaccacct gatactgctg
    13921 aacggttttt aaccgcatga gtaccttggc gaaggctagc gcgttggcta attacaacat
    13981 caaaaacaac tgattcgttt ggttcgatac cgaagatagc gtcgtttaat tcaactgagc
    14041 taacttcttt accagtttgg tcaaatagtt ttacgtttgc cattttaact gttttctcct
    14101 ttcttattat ttagcagctt taactgctga cttgatagtg ataagagatt tcttagcacc
    14161 tggtacgtta cctttaataa ggataacgtt cttttctggg ataacttgta caatttcaag
    14221 gttttgaact gttacacggt taccacccat acgtcctgcc aagcgtttgt ttttgaaaac
    14281 gcggttaggc gcaacaggtc ccatagaacc tgggcgacga tggtaacgag aaccgtgagc
    14341 cataggacca cgtgattgac catggcgttt gataacacct tggaaacctt taccttttga
    14401 tgtccctgtg acgtcaacaa catcaccagc ttcaaattgt tctacagata attctgcacc
    14461 aacttctaag ccttcaatgt ttttgaattc acgaatgaag cgcttaggag ctgtgtttgc
    14521 ttttgcaaca tggcctttgg caggtttgtt actcaagact tcacgtttgt catcaaaacc
    14581 aacctgaact gcttcataac cgtctgtttc aacagtttta acttgaagca caacgtttgg
    14641 agttgcttca atgacagtaa cagggatgaa ttcgcctgat tcagtgaaga tttgagtcat
    14701 tcccactttt ttccctaaga ttccttttgt catgagaaaa tatttccttt tcttaataat
    14761 atttcaaaaa gttttttatg agcgtttttt gtgctcaaaa aagtttttta cgagcgtttt
    14821 ttgtgctcat agcaagatac aaagagcgtc aaactcaaaa taaaaataga aaatctaaca
    14881 caaaaacttc tgtttcgagg aagatttatc tttttcatgt agagtttagc tcgtgttcaa
    14941 gttccatcaa acactaactg tacttgcaaa atctcaccga ttaaagtttg atttctacgt
    15001 tgacaccact tggaagatca agtttcatca aagcatcaac agttttctgt gttggattga
    15061 tgatgtctac caaacgtttg tgtgtacgca tttcaaattg ttcgcgagaa tctttgtatt
    15121 tgtgagtcgc acgaataatt gtgtaaagac tgcgttcagt tggaagtgga actggtccag
    15181 caactgtagc acctgtacgt gttgcagttt caacgatttt ttctgccgct gtatcaagtg
    15241 tacggtgttc gtacgctttc aaacggatac ggattttttt gtttgccatc ttttctcctc
    15301 tcgtctattt acgataatag gctagctcct caagaaaacc gacacctgtt gcgtggcaat
    15361 gcaaccgagc gtgtcgcaac ctcttgtatc attgctaaag ctgtattttt acagcaccac
    15421 aatataataa cagaatcatt tagtcattgc aagcttttta ggcatttttt tcaaaaaaac
    15481 taccttccta atgagaggta atttcttggt actttttaaa ttgtttagag agaataaacc
    15541 accgactggt attatctaac actgtcgcca tccagacccc tatgagtcca tattgccaaa
    15601 ccacaccaat cacataacca aggccaatgc gaatcaccca cattcctatg gttgttgcat
    15661 agaaaggaaa ctttgctttt cccaaaccct gccagacggc tgtataaact aaagtgcctg
    15721 ccgttgcggg agctcctagt aaagaaaaaa gtaaaacaac catggcggac ctttgagcat
    15781 cagtattctg tgtaaatagc ggcaagagac taggacctag cagataggtc aaggctccca
    15841 taaccagcat catgagggtg gataaaataa aagcttctct aataatatac cttatctcag
    15901 ttaccttacc gccccccagt tgcctagcca ctagaataat tgttgccgtt gccatggcta
    15961 agccaggcat gtaattaaac tgagtcaagg tttctccaat agcattacct gccaaggccg
    16021 ttgtcccaaa gcgaacaaca atgccaataa ttaggacatc tcctgctctc atcatcaaac
    16081 gttcaccagc agcaggtagt gataaatcaa aaataatttt gtccaaaggt ctcatcaatc
    16141 gtttcacaac ctgtttaata ggaataaact gacaaagtaa aaacataccc actaaacgag
    16201 ataaaaccgt cgcccaagca acaccaagaa gaccaaatcc ccatacatag atagacaagg
    16261 cagaaaaaat ggcattgagt acgtttatta ataagctcac ttgcatagga atcttaggat
    16321 acccttgagc tcgaacaata gctcctaagc tagttaaaag tcctagacta acaatcatac
    16381 cgccgacaat ggatagatat tgccctccaa ccaatgttac agaagcttca gctcctagcc
    16441 attctaacac ctgatgatgt ccaacaactg ataacaaccc taagccgacc gaaaggagga
    16501 gtgttacttg caagacacct gccatatagt ttaattgttt gttctgatta ttttctccaa
    16561 tacttcgagc aatcagacta gatacagcag ctcccagcgc gataaagagg gactgataaa
    16621 tactgataat gttgttagct atggagacac cagagactgc tacaagtcca atttgagcca
    16681 ccaggtaatt atcaaccatt cccattaaca tctgtaaaat attttctatc atagaaggca
    16741 gagctaaaga gaaaattttt cttctattat atatcattta tgtcccctaa taaaaaattc
    16801 ttgatcaaac gattttttca aacacagtca ctggactcat tcagttattt tggtccatta
    16861 atgaattcat aaagtctatc ttaatagcag agtcccaaga tacacgacac ttagtgttac
    16921 agtaacaatt gaccacatgc caattcttaa catttaccta acgtttataa ctaagaagac
    16981 gaagaacaaa aggaccccaa acgaattttt tctattatat aatatattct tcatttagca
    17041 actttcaatg tatcaaaata gcactctcga gtcaaaaatg gtttctgata ctcgagagtg
    17101 ctattttatt tggaaccaag tttaagcaac ttaggcttat ctcatattta atacatttgt
    17161 atgtttagct gatgaaatct aagaccttgc gcccttggat taaaccacgt tccatttcat
    17221 caaagacttc tggagcagtg tcaactggaa ctttttcgac aaccggaaca accagacctt
    17281 ctgcaccaaa ggcaaaggct tcttccaagt ctttacgtgt ccctacaagt gatccgacca
    17341 ctttgatacc atctaaaaca gtttttacga tagacagttc catgtattct gatggaagac
    17401 ctacggctac aactgtccca ccggcacgga cactatcaat tgcttggtta aaagcaactt
    17461 tagaaacagc cgttaccaca acaccatgtg ctccaccggt tttttcttga atatagcctg
    17521 gaacatcttc aatttctttg ccgttaacta aaatatctgc gccaacttct ttagctaact
    17581 caagtttatc attattaatg tccactgcga caacatgtgc attaaagact tttttagcgt
    17641 attgaacagc cagatttcca aggccacctg ccccaaagat aacaatccat tggcctggag
    17701 cagcacctgc ctctttaata gctttataag ttgttacacc agcacaagta atggaagaag
    17761 cttgagccgg gtctaaacct tctggaactt taactgcata atcagctgtt actactgcat
    17821 attcactcat tcctccatca acactgtatc cagcattttt aacactacga caaagtgtct
    17881 cacgtcctgt agtacagtat tcgcaatgac cacatccttc aaagaaccat gcaatagaga
    17941 cacgatcacc aacctttaag gatgttacgc cttctccaat ttcttctact ataccaatac
    18001 cttcgtgccc caaaatacgt cctggtacct gaccaaaatc gccatgtgca acgtgtaaat
    18061 cagtatgaca aacgccacag tattctactt taacaagcgc ttcaccatga ccaacatttg
    18121 gaagatcatg ctcaacaact tcgacacctg tactagcttg attaacaact acggctttca
    18181 tatcagtcct ccatctaata acgacttatt tgtaatcggt tacaaataaa ttgtacatct
    18241 tttcacaatt aaagtcaaca gaaacctgaa aagtttctga aacttaactg gttaatctta
    18301 tagctgtttg cctatctgca aaatacttaa ctacattttc tgacactgga tataaatgat
    18361 atatttagaa aataaaatga tttcttatga ctttaatcat aagaaatcat ttcctggtat
    18421 caacattaaa aatcacttac gtcgtcctgg acgttcagca taaccatagt aagcatcttc
    18481 aataatttct tgcatgtgat caaccattgg aagacgtggg ttagcaggtg aacattggtc
    18541 ttcataagca aggtaagcca attcacgaga atgttctttc cattcatttt cgtcgatacc
    18601 ttgagctttg aagttcattt gaataccaac tcggcaaccc agatcataaa cagctttcgc
    18661 ataagattcc actgcttctt ctggtgtaga agctggaagc cctaacaatt tcgcaatgtc
    18721 ttggtatttt tcatccgcac ggtagtaatt atacttaggc catgtcgccg ttttagctgg
    18781 acgagttcca ttatagcgga taacatacgg caaaagaatt gcatttgtac gtccgtgtac
    18841 ggtatggaat tgtgcgccaa ttttatgtgc cattgagtga gaaataccta agaatgcatt
    18901 ggcgaaagcc atacctgcca tagttgacgc attgtgcatc ttttcacgtg cttcaaaatc
    18961 ggctgtttta actgattttt caagattatc aaaaacaatt ttaatggctt gaagagctaa
    19021 accatccgta aagtcattgg ccatttgtga cacgtaagct tcggttgcgt gtgtcaaaac
    19081 gtccatacca gtatcagcag caataaagcc tggaacagtc aataccaaag ctgggtcaac
    19141 aatggctaca gttggtgtta atgagtaatc agcgattgga tatttacgat tatttgcttt
    19201 gtcagagata acggcaaatg gtgtcacctc tgaacctgtt ccagaagttg ttgggatagc
    19261 aacaaatttt gttttcttac caagttctgg gaatttgaac gcacgtttgc ggatatccat
    19321 gaatttttga acgaggtcat ggaaatcaac ttctggttgc tcgtagaaga gccacataac
    19381 tttggctgca tccataggag atcccccgcc aagggcaata atggtgtctg gtttgaaggt
    19441 acgcattaat tcagtacctt tcataacagt tgtaatgtct ggatctggtt ctacttcagc
    19501 aaagatctga taaacaactt tattgcgacg aagatcaagt tgttcaatga tacgatccaa
    19561 gaaaccaagc tcaaccatag cgtgatctgt aacaatcatg acacgttcaa cgtcacgaca
    19621 tttttgcaaa tattgaattg aatcacgttc gaagtatgtt tttgaaggaa ctttaaacca
    19681 ttgcatatta tttctacgtc ttcctacttt tttgatgttc aagagattta tagcactaac
    19741 gttatcacca actgcgttac gtccatacga accacaacca agagtcaatg atggcaagaa
    19801 agcattgtaa acatccccga taccaccaaa tgtagaaggt gaattccaga tgacgcggat
    19861 agcacggatt ctagttccaa attcttttgc caactctgca tctgctgtat gaatggcagc
    19921 tgagtgaccg agtccattaa attcaaccat ttgacgagct ttttcaacac cgtcttcacg
    19981 tgattcagat ttcaaaacag caatgactgg agataatttt tcacgtgtta aaggctcatt
    20041 ttctgaaact tctttacatt ctgcagcaag aatattggtt ccttctggaa cagtaaatcc
    20101 agcttgttct gcaatccaag tagctggttt tcctacaata tttggattta attttgcacc
    20161 agcacagttt ttgctatttg ctttggcacc aaaacagaat tcttcaagaa gggctttttc
    20221 ttttttattt acaaaataag tatggtaaga tttgaactct gctacaaaat cgtcatagat
    20281 ttctttatcg atgataacag cttgttcaga ggcacagacc ataccattat caaatgattt
    20341 agacatcaca atatcatgag cggcttgacg gatattagct gatttttcaa cataagctgg
    20401 aacgttacca gcacctaccc caagggcagg tttcccacat gagtatgccg ctttaaccat
    20461 cgcatttcca cctgtcgcaa ggatagtggc aatgccgtca tgattcatca aagcatttgt
    20521 tgcttcaagt gatggtgttt caacccactg cacacaattt tcaggagcac cagcggcaat
    20581 agcagcatca cgaacaatac gagcggcatg cgctgatgat tcttgtgctg atgggtgaaa
    20641 ggcaaaaata attggattac gtgtttttaa cgagatcaaa gatttaaaga tagctgttga
    20701 agttgggtta gttgttggtg taatcccaca gataacaccc accggctcag caattaatgt
    20761 caaacctgtc acatcatctt cttcaataat tcctactgtt ttttgatggc gcatgttatt
    20821 aaccacatgc tcacaagcaa atagattttt tgttgcttta tcttcaaaga caccgcgacc
    20881 tgtttcttca taagcatgtt tagcaagttc accgtgagca tccaaagcag caacagaagc
    20941 tttggctacg atataatcaa cttgttcttg gtcaagctta cgcatctctt caagagcagc
    21001 taaacctttt tgaacaagag catcaattgt cacagaaaca gaggttgttt caacagtatt
    21061 atgtccttca gtcatttgag actcctttat cttgttaaaa gtttcacaat tttgtttaca
    21121 aaattattat agcacttttt gaaattttgt aaatcatttc acaataaatt tgtgaagttt
    21181 ttttcaaatt atttctgaaa tcctatggta tcaatattct tcattaactc tttttcagaa
    21241 atatatctaa aaaaagccgt tttatttctg aaatcgcttt cttttaaaaa cctcaaagta
    21301 ctactatttt accatcatca tttgttcaca agaaaaagcc agagcacaat ggatctgact
    21361 tatctcttag acatttctta actttattta gctggttttt tagctgactt ctcaacagca
    21421 gtctggattg tggagacata tagttctgct ccttgactat cttcactata atgaacaccg
    21481 tcactgccat accaaatatc tggatgttca acagcaactt tataccagtc tgcaatagtg
    21541 acatacttgt attttttgga caatttaaga ccatagtctc tagcttctgc aacctgactg
    21601 gcatttttgg cattatatgg agaaaccaaa actaaacgat gaccatttgg caatgcctca
    21661 ataaaagact gaactgcttg agaatagttg tcaagcgagt taacacctac tgctaagaca
    21721 acagtcttag atagactctt agatttaatt tggttattaa ataaatcgaa agcttcttta
    21781 aaattccgac tgaccgctgc atccagttgc gcttgtggca taatttttga gaatgctgca
    21841 ctagagcgta atgctacaga atcaccaata atacctacgt cactcaaagc attagcgtct
    21901 cctgcagcta gtgtatgtgt ccgctccata ttactttgag cctgttgtag ggaactaacc
    21961 aacaattgtt tctcaaactt accaacttta ggcgctatca tacaagttcc taaagttaat
    22021 aatgctaagg cgagagtccc tcctacaatc cacttatagt aaggagaaca gtcaatttct
    22081 aaaccaagca ggtttggttt tctcccttgg accaaaggtt ctacaatata gtaagacaca
    22141 gtggcaaaca agattgaaaa gaaaactgtt agaataactg ccaaaatatg agacattaat
    22201 tggctaaaaa taatgtaaaa tggccaatgg aagaggtaaa tcccatagct aatatcagct
    22261 atataagtga tagctttagg ctcttgtaca tctggtgttt gctcatgaag aacacgcgct
    22321 gcataaatca taattgatgc gaataagcta gccaaagcaa agccaaatag ataggtcgtg
    22381 atatggttaa aatccaatgt gaccgttagc acaagcaaaa gtgtaaatgc tccaaccata
    22441 gcagcaagga catactggcg cggccataaa cgtacatttt tttgaaatcg aacagtagtc
    22501 tcgttaatac ctgttatcgt ggcaaacatc gcccctaaaa agaagggaaa actgtgagaa
    22561 agactcgaaa aataaatcag ggaaaaattt gaggtcataa aagatcttat aaacatgctc
    22621 aagaaactaa tagcaaatat tcccaaagaa atcaaaaaca gtagtcctct cagttgtttc
    22681 tgagtctcct tgcgtctagc taataaccaa acaaatacac cccaaaacaa gtaaaaatga
    22741 acttcaatag ctaagctcca cgtatgaaca aagagatgtg gaataaattg gctttcataa
    22801 ctacttcccg tcaatatttc ataaatatta gtggtaaatc ctaaaacagc tgtaatctga
    22861 cttcctatat tagcaatgaa atccttctta attaaaaacg taaaaggaat ggtcaataaa
    22921 atcattaaca ccaaaggagg aacaattcga taaaagcgtc tttttaaaaa accgataata
    22981 tcgatagact ctttttttgt gtattcatca atcaagaggg ctgtgattag atatcctgaa
    23041 aaggtgaaga aaatgtcaac accaataaaa cctcctggaa atacattttt aaaaaagtgg
    23101 tagagtaaaa ccagtaaaag tcctgttacc ctaacaaacg aaaaccattt tattctcatt
    23161 tttgaaatat cccctgttta aaaatccctt tatagacttt attattcttt gcttttaaca
    23221 cacctttgcc atttgcttgt cctttatgaa attccccgtt atataaccag cccgtcttag
    23281 cagtaaaagt tccttttcct tcaaataggc cattcttaaa agtaccctca tagatatcac
    23341 cgttggggta gacaagcttc ccttctccat tcattttatg gttaatcacg taaccagtat
    23401 agtgtatacg ccctttatca taggtcaaac ttgtcttatt cgaaattctt acgctaaaaa
    23461 cagaaattgc acaaaccaat atgacaatca ccgaaacaat ttccaacttc gcccgtgtaa
    23521 tactccattt ttttactata tcttgcatat ctatcatttc ttttactcaa cttctaatat
    23581 caatactctt tactcattaa acgagaaagc caatcctggc atccttttct aactaattgg
    23641 taggtttctt caaaatcgtt agtgtaccaa ggatcaggaa cacccccttc tctaaacaga
    23701 tagattttag agtcccattg atgttgcgac atctctttga gatttttcac attatcgcta
    23761 tccataccaa taatatagtc aaaggtgtta aaatcagtta tagttatctg cttggagcat
    23821 ttagttatat cataattaat ttggtaagtt tttaatatgg actgtgtacc tgagtgaata
    23881 gggtttccat gctcccaatc agaagtagca cgactttcta tcatcataac atcacttgat
    23941 actattgact tcattacaaa ctcagccatg gggcttcgac aaatattacc cagacagaca
    24001 aaacatactt ttttcattaa atactccttt gaattattat atcaaatttc taactgatat
    24061 cggagaaatc aatctaataa ttttctgtca acttatcaaa aaatccgaac acaaaaagca
    24121 ggttcagatt aattttctta gatttgaaaa atcattaagt gttttgatag ggatagccaa
    24181 gatgacgata agccttttga gtcgctacac gacctgttcg tgttcgcatg agaaagcctt
    24241 tttgaattaa gtagggttca tacatctctt caactgtatt acgctcctcg gcaatattca
    24301 cagataatgt ccccaaacca actggccctc cctgatacat ctcaatcatc gttcgtaaaa
    24361 ttttctgatc aatgtaatcg agaccttcgc ggtcaacatc taacatagtc aaagctctat
    24421 cagttatttg agccgttatg atgccatcac caataatttg agcatagtca cgcactcgtt
    24481 ttagtaatcg attagcaatg cggggcgttc ctctactgcg acaagctaat ttccgtgcag
    24541 cttcatggtc tatttttatt tcaaaaatag tagctgtacg ctccacaatc tctgtcaaat
    24601 ccttttcttg atagtattcc atgtgaccag tgataccaaa acgagctctg aggggattag
    24661 ataacatgcc tgcacgtgta gtagcaccaa tcaatgtaaa tggaggcaga tccaaatgaa
    24721 tactacgact agtatctcca gcgccaatca taatatcaat atagaagtct tccatagcac
    24781 tatatagcac ttcctcgaca gacattggca tgcggtgaat ttcatcaata aacaaaatat
    24841 cccctggttc taattcattt aaaatagcta ccaaatctcc agctttctca acggcaggac
    24901 ccgaagtttg ctttaaatta actcccaatt cattggcaat cacaaatgcc attgttgttt
    24961 ttcccagtcc tggaggtcca aataataaaa catggtctaa agattcgtca cgtcttttag
    25021 ctgcttctat aaaaatagcg aattgttcct taactttatc ttgtccaata tattcgtgta
    25081 gatattgagg gcgaagagtc cgatccgaaa actcctcatt tcccattaca ttattgtcta
    25141 aaattctagc cataggacta ttataacata aagtaaaaga gagttaacca agattccacc
    25201 aatcaaattc atgcattaca cgagcaactt taaatgcaac tactgcggct aatagtaaaa
    25261 atggcttaac tttttttaac atcttctatc tcccaaaaaa tattatttat aagagatagt
    25321 atagctatag taaatataaa taaacatgac atccatgtca taaaatcatt atttaaa
//
LOCUS       DAUCXI010000026        25169 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.026, whole genome shotgun sequence.
ACCESSION   DAUCXI010000026 DAUCXI010000000
VERSION     DAUCXI010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25169
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.026"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            133..294
                     /gene="sagA"
                     /locus_tag="VGY43_001143"
     CDS             133..294
                     /gene="sagA"
                     /locus_tag="VGY43_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HEQ4302332.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            516..1466
                     /gene="sagB"
                     /locus_tag="VGY43_001144"
     CDS             516..1466
                     /gene="sagB"
                     /locus_tag="VGY43_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HEQ4302333.1"
                     /translation="MSFFTKEQQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYMKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            1463..2521
                     /locus_tag="VGY43_001145"
     CDS             1463..2521
                     /locus_tag="VGY43_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEQ4302334.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENTLEPETFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNAPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSEALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQVLPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIVQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            2541..3899
                     /locus_tag="VGY43_001146"
     CDS             2541..3899
                     /locus_tag="VGY43_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEQ4302335.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVKCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            3874..4545
                     /locus_tag="VGY43_001147"
     CDS             3874..4545
                     /locus_tag="VGY43_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ4302336.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPKITLSLESIDSKTFFMGLVFCVFIVLIELVFLHGLRCWQKK
                     EWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKEVT"
     gene            4542..5225
                     /locus_tag="VGY43_001148"
     CDS             4542..5225
                     /locus_tag="VGY43_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEQ4302337.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLMALSYQDFLDV
                     LLSLFQFVVIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAIIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGIVILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGAMILTVT
                     YLMISCKEY"
     gene            5248..6171
                     /locus_tag="VGY43_001149"
     CDS             5248..6171
                     /locus_tag="VGY43_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302338.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            6180..7307
                     /locus_tag="VGY43_001150"
     CDS             6180..7307
                     /locus_tag="VGY43_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302339.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIRLTG
                     VSPSLLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILALIGMRKQVTT"
     gene            7304..8422
                     /locus_tag="VGY43_001151"
     CDS             7304..8422
                     /locus_tag="VGY43_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302340.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSSQLYHRLMLSN
                     LSRFRYMLSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGGTLSQAWPYLLALMGTALALIIFSSLLLKPTRL"
     gene            8994..11725
                     /locus_tag="VGY43_001152"
                     /pseudo
     CDS             8994..11725
                     /locus_tag="VGY43_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
     regulatory      11890..12005
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            12003..12503
                     /locus_tag="VGY43_001153"
     CDS             12003..12503
                     /locus_tag="VGY43_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEQ4302341.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            12697..14655
                     /gene="ligA"
                     /locus_tag="VGY43_001154"
     CDS             12697..14655
                     /gene="ligA"
                     /locus_tag="VGY43_001154"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEQ4302342.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTAVVAKRELATFLYQE
                     ASPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKENFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRKL"
     gene            14669..15691
                     /locus_tag="VGY43_001155"
     CDS             14669..15691
                     /locus_tag="VGY43_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ4302343.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDEALVLDQDELEIEEIVKKFAHEVEDL
                     EQELEE"
     gene            16083..16280
                     /locus_tag="VGY43_001156"
     CDS             16083..16280
                     /locus_tag="VGY43_001156"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEQ4302344.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            16315..17031
                     /gene="atpB"
                     /locus_tag="VGY43_001157"
     CDS             16315..17031
                     /gene="atpB"
                     /locus_tag="VGY43_001157"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEQ4302345.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            17049..17543
                     /gene="atpF"
                     /locus_tag="VGY43_001158"
     CDS             17049..17543
                     /gene="atpF"
                     /locus_tag="VGY43_001158"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEQ4302346.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            17543..18079
                     /locus_tag="VGY43_001159"
     CDS             17543..18079
                     /locus_tag="VGY43_001159"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEQ4302347.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTN
                     LDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            18095..19603
                     /locus_tag="VGY43_001160"
     CDS             18095..19603
                     /locus_tag="VGY43_001160"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEQ4302348.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            19619..20494
                     /locus_tag="VGY43_001161"
     CDS             19619..20494
                     /locus_tag="VGY43_001161"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEQ4302349.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            20656..22062
                     /gene="atpD"
                     /locus_tag="VGY43_001162"
     CDS             20656..22062
                     /gene="atpD"
                     /locus_tag="VGY43_001162"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEQ4302350.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDHLPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            22075..22491
                     /locus_tag="VGY43_001163"
     CDS             22075..22491
                     /locus_tag="VGY43_001163"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEQ4302351.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            22757..23014
                     /locus_tag="VGY43_001164"
     CDS             22757..23014
                     /locus_tag="VGY43_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEQ4302352.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFR"
     gene            23079..24350
                     /gene="murA"
                     /locus_tag="VGY43_001165"
     CDS             23079..24350
                     /gene="murA"
                     /locus_tag="VGY43_001165"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ4302353.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTHLRGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            24354..24542
                     /locus_tag="VGY43_001166"
     CDS             24354..24542
                     /locus_tag="VGY43_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEQ4302354.1"
                     /translation="MTNGLKYVLEQMLLLFIIAALACLFLAIGLMIGYSFMGDGHSPW
                     HILSMDKWAELVNKFTGK"
     gene            24578..25169
                     /locus_tag="VGY43_001167"
                     /pseudo
     CDS             24578..25169
                     /locus_tag="VGY43_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990412.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
BASE COUNT         7801 a         4173 c         5158 g         8037 t
ORIGIN      
        1 atagttgttg tgttacaaca gtacaattga gctagccttg tccttgttgt gttaacttta
       61 tttttaaaat aaggttaaaa ataaacgact cgtgttctta tcagttactt attagataag
      121 gaggtaaacc ttatgttaaa atttacttca aatattttag ctactagtgt agctgaaaca
      181 actcaagttg ctcctggagg ctgctgttgc tgctgtacta cttgttgctt ctcaattgct
      241 actggaagtg gtaattctca aggtggtagc ggaagttata cgccaggtaa ataatctatt
      301 tagcatctct atgtgatagt gatattaagg taatgagttt gctagcaact aagttatctt
      361 tggtaacttc tgattataga tgaatggcat agaggtgtta gaaaacatga gacaaaagta
      421 atcttcttga tgctaacgtc tcaggtaatt agcaggtact agacagtacc tgctaattac
      481 tatatgttta gtaaaatgag ataggaaaga tagttatgtc attttttaca aaggaacaac
      541 aacctaaaga gaattgtccg ccaataactg ttgaaaaagc aaggcaattg tttgaattta
      601 atacaaacca cttgtcctta tcggattacc atcatcaaac ggtgctaaaa acgtcaaagc
      661 agctagttgc tcaacattta atgcctaatg caaccgataa tcttagtcaa cattttttga
      721 tgaactataa agctaataat aattatttag gcttccaagc tagtattgtc gactttttta
      781 cagattctgc cgttgctaat ttttcaagta gttacgttta tgaaagtcag gaaaagataa
      841 ttcgtttacc aaaacctacc aagatatcaa ctgctctgtc gacatgtatt ataaaacgaa
      901 gaagtcatcg tcaattttca gatagacaaa tgcctcttca agatttatca aacattcttt
      961 attatgcatg tggtgttagt tcacaagcat caattagaga tggagcatca gataagatta
     1021 cactcagaaa ctgtgcttca ggtggaggtt tataccctat tcatttagtt ttttatgcta
     1081 gaaacatcag taaattaata gatggtttct atgaatatct accctatcag catgcactaa
     1141 ggtgttatcg gcatagctct gaggaaaacg ttagagattt tgcggaatac ggtgctatta
     1201 atgctgaaaa ttgtaatatt attattattt atgtctacca ttacatgaaa aatacacgta
     1261 aatatgggaa tcaggcgact gcctatgctt ttattgaatc aggagaaata gcccagaata
     1321 ttcaattgac tgcaactgcc ttaacttatg gaagtattga tattggtggt tataataagg
     1381 aatatctcca agaattatta gatttagatg ggctaggaga gcatgtgatt cacatgacac
     1441 tcgtaggaac taaggagtct caatgaaata tcaacttaat agtaatgttc gtgtcgtgac
     1501 atttcaagat acattttgtt ttagaaaagg aatctgggac tttaatgaag ccattctaga
     1561 tttgacacaa gaacctcaaa atttaaagat agtttatcaa gaaatagttt cacagttggt
     1621 taagggagta gccattgata ctgaaactta tgaaaatact ttagaacctg agacgttcgc
     1681 taatttaatg gaagtcattt caggcttgta ttacaatgat atgctgatgc ttgaggatga
     1741 ctacaatctt gaagaaaatg tcatgaaaat tttaatgggt aatttccgtt ttatggcgca
     1801 agcaggtcat atggtaagca atgctcctgt tttgtttatc agtgattcga cttatgttaa
     1861 tgaatctgct gagttgctag ctgaacaact gcatttacaa ttgcaagtgg ctagtgatga
     1921 cttaaaaatg ttaattcagc agacagatgt tagttcgcgt ttagatgctt tggagcatcg
     1981 ccgtaacatg aattgtttat cagaagcctt gtgcgattac caaagtatta ttatttgtca
     2041 agaacgcttg aatattatga tgttgcgaca cttgaatgaa gttagcgtag ctatgaaaaa
     2101 acaattagtg attggttttg tagatggacc attcttgcac acttgtactt tgaatcctcc
     2161 ccatagtgct gactttgata gcttagaaag aagagttttg gcacgtttac aagactcaac
     2221 tctctatcaa cattttgcta atcaggtttt accagccaca caagatgtga gccaggccta
     2281 tttaccattg ttaaatgttt taatgaattt agtcgttagc gaagctttca ttattgttca
     2341 aacaggtagt tctaaatttg agggacgttt attaagcatt tacttaccga cgcttgagat
     2401 tcaggtccaa gatattttga aaatgtctaa ttcacagaca caaggagctt tggcaaaatt
     2461 aaagtatgag gatcagcaga tatcaacacg tgagattgtt aaaaaactcc ttgacgagta
     2521 acctataagg agaatctatt atgttatact attatccttc ttttaatcat atttttgatg
     2581 aattaaaaag tttaagtggc aatcgaacag gtatcttaaa tcaatctcaa gttccagttt
     2641 gcaaccatcc tcacgatgtt tacttaaaaa gtattactgg ccaaatgcca gattatcata
     2701 aacaatttat aggtgagttg agtcaagtta gttatcacat tattggttac ggcagttact
     2761 acgaagaagc acttatcaag tatttaggag aaagtattga acgctatgct actgtaattg
     2821 ccggagactt actatcagat cggattgtct atgcttctta taatgagtta aaactgttac
     2881 ataaagtgat gcctttagaa tacttgcaag tgtttaccca agaacagatc gcattatctt
     2941 gtgacttgca aatgatgatg tgcgataaaa tggtaactga gaacgatgta ttgggctggg
     3001 ttaaatgtcc catgttcttt gaggacgcag agatgtatgt tccagctcaa atgctttgtg
     3061 ttgggtataa aacaaatgag actgtaggag aaagacggat aataccagga ttttctacgg
     3121 gaacagcttc tcacaaaacg ttagaagcgg ctatgtgcaa cagtttgatt gaatacatcc
     3181 agatcgattc aatgatgctt agctggtata ctaagaagcc ttgccccaag attattgttg
     3241 atgatcctga tattgaagtg attttagaag aagctagact gggaaaagac agtctatacg
     3301 acattattcc tatcgatatg actgtaggag aagataatcc tctttatacg tttggaatca
     3361 ttctcaaaaa taaatatgat gaagggcctt acctcttgtt tggagtgcag gctgggttag
     3421 atcctaaaca tgctttgcta agagggatca tggaagcttc agctattagc tatagttact
     3481 actataatct tttatatcaa aaagcttccc ttgcaaatat tgaatgcgaa gaacctttgt
     3541 ttttagattt agatagtaat gtcttctatt atgcacatcc caaggaccaa gaccataaat
     3601 ggaaggcctt tgaacctttg atttcaggag aagttctgtt aagtgatttg gaagatcatt
     3661 ctggtaaaga taaaaaagaa gatttgaaga ctttattagc ttatgctaag aaagtcagtc
     3721 ctaatgctgt ctttttagat attacacctc ctgaagctct agaaaaaggc tggtacgtca
     3781 cgcgagttct gatgccagaa cttcttgaaa tgtgtatacc agcatttcct tttgctaatc
     3841 atccacgaat gagacagttt ggaggtgtaa caaatgcctt tgtccatcca atgccttaat
     3901 ctttgttttt tgttggtaac tttttgtcct tcaattccta tgcaagctat ttttggaaaa
     3961 gaagatagtg gttatgcatt taatttaatt ggttttctaa gagcaactct gatttatgac
     4021 attttggctt tggtaagtat ttatgttttg tcacctaaaa taaccttgtc tcttgaaagt
     4081 attgatagta agacgttctt tatgggactt gtattttgcg tctttatagt actgattgaa
     4141 ctcgttttct tacatggttt acgttgttgg caaaaaaagg aatggcttcc tgcaactttc
     4201 tcgtttgtag gaacgacaaa tgattggtct aagattggct atcctttatt actagcttta
     4261 tttgaagaga cgatttatcg ttttttgtgg tttaatatat tagcttttca atggcattta
     4321 ccaacaatta ttgttttaat tgtaactagt ttttgctatg ctttaaatca cttattgatg
     4381 gggaaatcca ttttttatgc taagttggta acaggcatca tttatggtag tatttacatg
     4441 ctgactagtc aattgtggtt ggttgtgata atgcatgtag gaggtaactt gctagttgag
     4501 tgtcttagcc atcttcaaac aaaaaagaag aaggaggtga catgatgcta ttggttttgc
     4561 tgtcgttttt aggtctaact actctttggt tgaccagtta tcgaagacgt tgtttggcta
     4621 gatggcatct tcaatggtta atggccttat cctatcaaga ttttttagat gtcttactga
     4681 gtctgtttca atttgtcgtt attatacttg ttttgttctt ttactcagct actattaatc
     4741 taggagaggt tctgaccttt ttgacacaaa ctagctggca ttggcagatt ctttgttatt
     4801 tagtgttgta tcttatggcc atcatagaga tgacgctttt agttttaatt cttatctttg
     4861 atgttttgct ccagaaagat agtcgattgc tctttaaaaa aataacttgg ctgcctttta
     4921 gacaagataa accagtctta agtatacttt tgctaggcat agttattcta gtagacagtc
     4981 tcttttattt gggcttgctt atattattag gagaacagtc gctaacaagt ttagcaacgc
     5041 ttattttagg ctatgggata gtcaaggctt gtcgctattc aggttggtta aatgtactat
     5101 tagctttttg tcttttcact atagttggac tatgggcagt tacggcaact ttattatatg
     5161 gttggctagt aggtgcgatg atattaacgg tgacttattt gatgattagt tgcaaagagt
     5221 attagcaata ttaaaaagga gtgatatatg agttttgtac aattaacaaa tgttgtcaag
     5281 tcctacaaaa acggcaagaa agctgtcaat gatgtttcct tgtctattga agcaggtaat
     5341 atttatggtt tgttaggacc aaatggtgct ggtaagtcta ccttgattaa tcttatctta
     5401 ggcttgatcc ctttgagttc cggtaaaatt actgttttag ggcaatccca aaagactatt
     5461 cgaaaaataa gttcgcagat aggttatgtt cctcaagaca ttgctgttta tccagaccta
     5521 actgcttatg aaaatgtaga actatttggg tcactttatg gcttaaaggg agctcagctt
     5581 aaaaaacaag ttctaaaaag tttagaattt gtgggactac actcccaagc taagcagttt
     5641 ccaagtcaat tctcaggagg aatgaagaga cggttaaata tcgcttgtgc gctagttcat
     5701 tcacctaaat taatcatttt tgacgaaccg actgtaggga ttgatcctca atcacgtaat
     5761 catattttag agtcgattcg tttgctaaac aaagaaggtg ccacagttat ttatacgacc
     5821 cattatatgg aagaagtaga ggctctttgt gattatattt ttattatgga tcatggtcaa
     5881 gttattgaag aaggacctaa atttgaactg gaaaaacgtt acgttgcaaa tctagcaaac
     5941 cagattattg taactctaac agattcacgt catttggaac tggcagataa gcctgattgg
     6001 tctttgatag aagatggaga aaaactcatg ttgaagattg ataatagtga tatgacatca
     6061 gttgttcatc agctcacaca ggccaatatt acttttagcg agattagaca taaccatttg
     6121 aatttagaag aaattttctt acacttaaca ggtaagaagt tacgagatta gaggttacta
     6181 tggttttatt tcatttaatc aaaaaagaaa gtttacagat ttttagaaac cgaacagcct
     6241 tattgatgat ggtgattttt ccaattttga tgatcgttat tttaagtttt gcctttaaat
     6301 caagttttaa tactgcgaca acagtcccta aattgaccat tcgttaccaa ttagagggtg
     6361 aaaaaacgga ttaccagaaa aattttcttg cttttttaaa agttttaaac caaaaacttc
     6421 atttagaggc taaacctagt aattctcttg aaaaagatcg acaaagggtc agtgaaggag
     6481 ccttaacggc tgttttagaa gtgaagaaga atcagaccat taaggttatt actaataata
     6541 ttaatcagca aaatgcagat ttaatcaata tgctagtaaa aaattatgta gataatgcta
     6601 aaacttatga ctcgatagca gctctttatc ctcaacaatt aaatcatatc agaaagcgaa
     6661 gtgtggacta tgttaaggtc agttcaatac agacaagtaa aggaatgaca tcagctgatt
     6721 attatgctat ttccatgttt accatgatta ctttttatag tatgatgtct gcgatgaacc
     6781 ttgttttgtc agatcgtcaa caacggatta caaatcgtat tcgcttaaca ggagtttctc
     6841 caagtctttt agtctttggg aaattaatag gtgctatgtt agcaacaact gttcaattga
     6901 gtcttttata catttttaca aggtttgttt tacgagttaa ttggggcact aatgagtgga
     6961 tgcttattgg tataacagcc tccttagtct atctctctgt agctataggt atcgggctag
     7021 gcataagcat taaaaatgag gcttttttaa cggttgcatc caatactatt attcctatat
     7081 tcgccttttt aggaggcagt tacgttccgt tgacaacatt acacagctct attattaatc
     7141 aattgtcgaa tatatctcct attaaatggg ttaatgatag tttgttctat cttatttttg
     7201 gtggtcaata taatccgatt cctgtaactt tgatcgttaa tattagtatc ggaacaattt
     7261 ttataatatt ggcattaata ggtatgagaa agcaggtgac gacatgattt gttttataaa
     7321 aactctattt gttaagataa agcgcaaaaa aacaagttat gtgacattct ttttaatgcc
     7381 tattttaacg acacttttgg ctttatcttt gagtttttca aataataatc aggctaaaat
     7441 tgggatatta gataaagata atagtcagat atctaaacaa tttattgctc aactaaagca
     7501 aaacaaaaag tacgacattt ttaccaaaat caaaaaagag catattgatc actaccttca
     7561 agataaatct ctagaagcgg tattgactat tgataaaggg ttctcagata aagtgttgca
     7621 aggaaaatct caaaaactca atatacgttc gattgctaat agcgaaatta cagagtgggt
     7681 aaaggcacag accaattatc tattggaaaa ctataatatt ataggggatg tggctctagg
     7741 taacgaagat acttttaata gaattctcca aaaaaaccaa cagttaaact atgatgttaa
     7801 gcaagtaact ttgacagacc gatcacgtag caaagcagta tcttccacaa cgacaggatt
     7861 tttgcttatt ctaatgttag gtagtacgag cgtgatttac agtggtattt tggcagataa
     7921 atctagtcag ttataccatc gattaatgtt atcgaactta tctcgttttc gctatatgtt
     7981 gagttacgtc tgtgtaggat ttgttgcttt tacgattcaa attgtcatta tgctgagttt
     8041 gttaaaagta tttaatatta gtttttttgt tccgacatca cttcttttga ttattttttt
     8101 cctttttagt ttattagcga taggctttgg cctgctgatt ggagctatca cacaaaattc
     8161 ccaacaaagt agccagttag ctaatcttat tgtaatgccg acttcaatgt tggctggctg
     8221 tttatggcca ttgtctatta cgccttctta tatgcaagca attggtaagt tattaccaca
     8281 aaattgggtt ttatcagcca tagctatttt tcaaagtgga gggaccttat ctcaggcttg
     8341 gccatacttg ttagctctaa tgggaacagc actagctttg attatttttt caagtttatt
     8401 attaaaacct accagactat aattagtctt ttgttaaaaa atactttcct aattagctaa
     8461 ctaccaggta gcccttttat tggcttatat gcaataaaag ggttgctttt tgcttatatt
     8521 ttctctagtg cacttatctt ttgttaaaag cgattgcgat gttactgttg ttactgtgtt
     8581 ttttagagag catattatca aaagcgacct ctctagaaag ttcgtttttg ttgataaatg
     8641 agttgtcaaa gtattttaaa aaaacgtttt caataaacat aaaaactaat gttattaaaa
     8701 aaaggtgtaa aaacgtattt attttatgaa atgtttttgt tacaataagc atgtatcgaa
     8761 tgctataaag ctgtcttgtt cgctatcagg ggtgcttgtg atgttatgtc agatcaaaca
     8821 agtctttaat tgggtgactt aacagattaa aagaaaagat ctaatcgtgt tacttgatag
     8881 tataattaat gcaaacagaa agtgtatccc aattcatagt ctcaggtgga ggttaatatt
     8941 caaaaataaa atcttgttgt tgtcttaaac taatcacatt aaaaggagat atcatgatta
     9001 acaagaaata tataatacct gtttcattgt tgacactagc tattacgctt actagtgttg
     9061 aagaagttac ttcacgccaa aatttgactt atgccaatga aatcgtaaca caaaggccaa
     9121 agagagaatc tgttattagt gataaatcga attttcccgt catatcacct tacctagcaa
     9181 gtgtggattt tggtgagaga aaaacacctt tgccaacacc tgataaagga gtaaaagtaa
     9241 ctactgaaca gtctattgct caagtaagaa aggggcctga agaaagaacc tatactgtta
     9301 ctggcaagat tacgagtgtg atcaatggct ggggaggcta tggcttttat attcaagata
     9361 gtgaaggtat tggactttat gtttatcctc aaaaagattt aggatacagt aagggagata
     9421 ttgttcaatt aacaggtaca cttactcgct ttaaaggtga tttacaactc caacaggtga
     9481 ctgcacacaa aaagttagag ttatcttttc cgacttctgt taaagaagca gtaatatcag
     9541 aattagaaac aacaacaccc tcaacattag ttaagttatc tcacgtgaca gttggagaat
     9601 tatcaactga tcaatataac aacacatctt tccttgtaag ggatgatagt ggtaaaagta
     9661 tagttgttca tatagatcat cgtacagggg ttaaaggggc tgatgttgtt actaaaataa
     9721 gtcagggtga tttgattaac ctcacagcca tattgtctat tgttgatggt cagttacaat
     9781 taagaccgtt ttctcttgaa caattggaag tggttaaaaa ggtcacaagc tcaaatagtg
     9841 atgcttcatc tcgtaatatt gtgaaaatag gcgagattca aggagctagt catacgtcgc
     9901 cacttctcaa aaaagcggtc accgtagaac aggttgttgt cacttattta gacgattcca
     9961 ctcattttta tgttcaagat cttaatggtg atggtgattt agcgacttca gatggtattc
    10021 gtgtttttgc taaaaacgct aaggttcaag tcggcgatgt tttgaccatt tcaggtgaag
    10081 tggaagaatt ctttggtcgt ggttatgagg aacgtaagca gactgacctt accatcaccc
    10141 aaattgtggc taaagcagtg accaaaacag ggacagctca agttccatca ccgcttgttt
    10201 tagggaaaga ccgtatcgcg ccagccaata ttattgataa tgatggcttg cgtgtgtttg
    10261 atccagaaga agacgctatt gattattggg aatcaatgga aggcatgtta gtggcggttg
    10321 atgatgctaa aatccttggt ccaatgaaaa ataaagaaat ttatgtctta cctggctcta
    10381 gtacaagacc gttaaataat tcaggtggag tattacttcc agctaattct tataacacag
    10441 atgtgattcc tgttcttttc aaaaaaggca aacaaattat taaagcagga gactcttaca
    10501 aaggaagatt agctgggcca gtatcttata gctatggtaa ttacaaggtc tttgttgatg
    10561 acagcaaaaa catgccaagt ttaatggatg gtcatctaaa acctgaaaaa acaaacttgc
    10621 aaaaagatct tagtaagtta agcattgctt cttacaatat tgaaaacttc tcagccaatc
    10681 cttcttcaac taaagatgag aaggtcaaac ggattgccga atcctttatt catgatctga
    10741 atgctccaga catcattgga ttaattgaag tccaagataa taatgggccg actgatgatg
    10801 ggacaacgga tgcgacacaa agcgcgcaac gcctcattga tgctattaaa aaactaggcg
    10861 gcccaactta tcgttatgtt gatattgctc cagaaaataa tgttgacgga ggtcaaccag
    10921 gtggtaatat tcgaacagga ttcctctatc aaccagagcg cgtcagcctt tctgataagc
    10981 caaaaggcgg tgctcgtgat gctctaactt gggttaatgg agaattaaac cttagtgttg
    11041 gtcgaattga tccaactaac gtcgcttgga aagatgttcg taaatcacta gcagcagaat
    11101 ttatcttcca aggtcgtaaa gtcgttgttg ttgcaaatca tttgaactct aagcgtgggg
    11161 ataatgctct ttatggtcgt gtgcaaccag tcacttttaa atctgagcaa agacgtcacg
    11221 tcttggctaa tatgctagca caatttgcga aagaaggggc aaaacaccaa gctaatattg
    11281 tgatgctagg tgactttaat gattttgaat tcacaaagac gattcaatta atcgaagaag
    11341 gtgatatggt taacttggtg agccgacatg atatttcaga tcggtattct tattttcacc
    11401 aaggcaataa tcagaccctt gataatatat tagtttcacg ccatttactt gatcactacg
    11461 aatttgacat ggttcatgtg aattccccat ttatggaagc tcacggacgc gcatcagatc
    11521 atgatccatt gttacttcaa ttatcatttt ctaaagaaaa tgataaggca gagtcttcta
    11581 aacaaagtgt aaaagctaaa aaacttcaaa aggaaaactg ttgccaaaaa caggagatag
    11641 tcttgtttat gtgataacac tactaggaac ggctagttta ttagtgccta ttttattatt
    11701 gactaaaggc aaaaaggaat catagcgatt tgaagaattg gagttcataa agagtcgtta
    11761 aaggcttgat atacttacgt tagaccttaa gctaaaatgg atgactatat aaaaactaag
    11821 attgataaca aaagaagata acaataagac agctttactt gctaaagact tttgtcaagc
    11881 taattgtttt atggtacaat gtaaccgttg ctttgcaacc cttggtgctt agttcccttt
    11941 caccaagcat attagaaacg tagatagctt ttgagagtta tccagacgtt aaaggagaaa
    12001 aaatgacaaa attgactgta cacgactatg ttcacattgg gctagtagct gccttgtatg
    12061 ttgtcttaac tattaccccg cctttaaatg cgatttctta tgggatgtat caatttagaa
    12121 tatctgaaat gatgaatttc ttagcttttt atcatcgcaa gtatattatt gcggtgactc
    12181 ttggatgtat gattgctaac ttttatagtt tcggactgat tgatgtcttt gtaggcggcg
    12241 gttcaactct tatttttgtg accttaggtg tgattttgtt tagtaagtat caaaaagatt
    12301 atctttttaa tggcattttt aataaagctt ttgtttactt ttctttcttt tttgcaactt
    12361 ccatgtttac tgtagcaatc gaactttact tctttggagc tccattttta ttaacatggt
    12421 ttacaactgc gttaggagaa ttagtatctc tgctcatagg atcacttatt attgataagt
    12481 tgtctcaaag aatttccttt tagtaatgca tcatactcaa aagagttggg tcaataccct
    12541 tctctttttt atgttgtttg taatgttaaa atcgttctag atagaaatat ttaacacttt
    12601 agctaatagt accatatgga gtggccaacg attacttttg atgttgttat gatatagaaa
    12661 tagctcattt gttatctttt atgataaaat aaaagtatga aaaaacgcat aaaagaatta
    12721 acagatcttc ttaaccgtta ccgttatgac tattatacta aagatgcccc atcagtttct
    12781 gacagtgact atgataagct ttatcgtgaa ctggtgactt tagagcagtc atatcccgag
    12841 tatgtcttgc aagatagccc aacgcagcag gttggaggga ctattttaaa ggggtttgaa
    12901 aaatatcgac atcagtatcc gctttttagt ttgcaggatg ctttttcacg tgaggagctg
    12961 gatgcttttg ataagcgcgt caaagccgaa tttccaaatg ccacctatct agcagagtta
    13021 aaaattgatg gtttatctat ttccttgagt tatgagaatg gcttcttaca ggttggagca
    13081 acacggggtg atggcaatat cggtgaaaat atcacagaaa atatcaaaaa aataaaggat
    13141 attcctcacc aattgagtga gcctttaacc atcaccgttc gaggagaggc ttacatgtct
    13201 cgtcagtcct ttaaagcgat caatgaagca cgccaagaaa atggggagac tgaatttgct
    13261 aatcctagaa atgctgccgc tgggacacta aggcagctag atacggcagt ggttgctaag
    13321 cgtgaactag ccactttttt gtatcaagaa gctagtccga cagctagaaa tcaacaaaat
    13381 gaggtcttag cagaattagc agatctaggt ttttcagtaa atccgtatta tcaactcaca
    13441 tcttctatgg atgagatttg ggattttatc aaaactattg aggcaaaaag agatcaatta
    13501 gcttatgaca tagatggcgt tgttattaaa gttaatagcc tagccatgca agaagagcta
    13561 gggtttacgg ttaaagctcc acgctgggcc attgcttaca aatttccagc agaagaaaaa
    13621 gaggcagaaa tcctttcggt tgactggaca gtgggacgaa caggcgtggt cacacctaca
    13681 gcgaatctaa ctcctgtgca actagcgggg acaaccgtga gtcgtgcaac cctacataat
    13741 gtggattata ttgccgaaaa agatatccgt attggcgata cagtgattgt atataaggca
    13801 ggggacatta ttcctgctgt cttaaatgtc gttatgagta agcggaacca gcaagaagtc
    13861 atgcttattc ctaaactatg cccatcttgt ggtagtgaat tagttcattt tgaagatgag
    13921 gttgctttgc gttgtattaa tccgttgtgt cctagtttga ttcagcgaag tttggagcat
    13981 tttgcaagtc gtgatgccat gaacattact gggctgggac cagctattgt ggaaaaacta
    14041 tttttagcgg ggtttgttca tgatgttgct gatatttacc agttgaccaa agaaaatttc
    14101 atgcaattag atggcatcaa agaaaagtca gctgataaat tgctcgctgc gattgaggct
    14161 tctaaatcaa attcagctga aaaactgtta tttggtctag gaattcgtca tattggctct
    14221 aaagttagtc gcttaatttt agaggtatac ggagatattt ctgctctttt aaccgctaaa
    14281 gaagaggaga tcgcaaggat agatggcctt ggctcaacga ttgctcaatc acttactcaa
    14341 tactttgaac aaaaaacggc tgcgatttta gtagacgagt taaagacagc aggtgtcaac
    14401 atgcattact caggtcaaaa agttaatagt gacgcagcgc tttttggtct aactgttgtt
    14461 ttaactggca aattaaatca gctgaaccga aatgaggcca aagataaatt agaggcatta
    14521 ggtgccaaag ttactggaag tgtatctaag aaaacagatt tagttattgc aggtagtgac
    14581 gctggttcta agctagaaaa agcaaagagc ttaggaattc ggattgaaga tgaagattgg
    14641 ctacgaaagc tttaagtgag gtaatgttat gaaaaaacaa ttgagagcac gtctcattta
    14701 taatccaacg tcaggacaag aacttatgag aaaaagtgtt cctgaagttt tagacatatt
    14761 agaagggttc gggtatgaaa catctgcctt tcaaacaaca gcacaaaaga actctgctct
    14821 aaatgaagca agaagagcgg caaaggcagg ttttgattta ttgattgctg ctggaggtga
    14881 tggcactatt aacgaagtgg tcaatggaat tgctcccttg aaaaagcgcc ctaaaatggc
    14941 cattattcca acaggtacca ctaatgattt tgctagagcg ttaaaagtac caagaggaaa
    15001 tccgagccag gcagcaaaac ttatcggaaa aaatcagact atccagatgg atattggtag
    15061 agctaagaaa gatacttatt tcatcaatat tgctgcagca ggaagtttga cggaattaac
    15121 ttacagtgta ccaagtcagt taaaaacgat gtttggatac ttggcttatc ttgctaaagg
    15181 agtagaactg ctcccaagag ttagcaatgt gcctgttaaa attacgcatg acaaaggcgt
    15241 ctttgaaggt caagtttcta tgatttttgc agctattacc aattctgttg ggggatttga
    15301 aatgattgct cctgatgcaa aactagatga cggtatgttt acgctcattt taataaagac
    15361 agcaaatctt tttgaaattg tacatctttt gcgtttgatt ttggatggtg gtaagcatat
    15421 tacagatcgc cgtgtcgaat acattaagac cagtaaaata gtcattgaac cccaatgtgg
    15481 taagcgaatg atgattaatt tagatggcga gtacggagga gatgctccaa ttacattaga
    15541 gaacctaaaa aatcatatca ctttttttgc agatactgat ttgatttctg atgaagcttt
    15601 agtcttagat caggacgaat tggaaattga ggaaatcgta aagaaatttg ctcatgaagt
    15661 agaagactta gaacaagaat tagaagaata atacaatagt tattagctac tgacagttta
    15721 gtcaaatgca ctactattag aatctaagat ttttaaatca attgaggtag tgttttttga
    15781 tgcgctcaaa gagtcaattt attcatatga ggggcccatt tgaggtctct cttttttgat
    15841 catatgcaag aaaatgccat gttttagggg tgttattata ccctttttgg aatcttgttg
    15901 cctttttgtt ataataagag tgtaattcta tttttaaaaa gatcttaaca aagacagact
    15961 cgtttatcaa aaaggttagt attagtctaa gaaagcgtac tcagtctaaa gaaatctgtt
    16021 gacattctta attttaagga atagaatagc aaagtaaaaa aaatttaaag gagtattcta
    16081 ctatgaatcc tattttcgca ttggctttgg cctgttttgg tgtttctctt gccgaaggtt
    16141 tcttgatggc aaatcttttt aaagcagcat ctcgccaacc agaaatcatt ggtcaattac
    16201 gttcattaat gatcttgggt gttgccttta tcgaaggtac tttctttgtt acccttgtta
    16261 tggccttcat tcttaaataa cagcctattt gataatagaa aaggagggtg ttagatggaa
    16321 gaagctaaaa tacccatgct aaagcttggt ccaataacct ttaatttgac cctacttgct
    16381 gtttgtattg tcacaattgc tgttatcttt gcctttgttt tttgggcaag tcgccaaatg
    16441 aaattgaaac cagaagggaa gcaaactgct ttagaatatt taatcagttt tgtggatggt
    16501 attggagaag agcacttaga tcataatcta caaaaatctt attcgctgtt actctttacc
    16561 atttttctct ttgtagctgt cgctaataat ttagggttat ttactaagtt agagacagtt
    16621 aatggctata acctatggac ctcgccaaca gccaatctgg cttttgacct tgctctatct
    16681 ctttttatta ccttaatggt acacattgaa ggggttagac gtcgtggctt ggttgcccat
    16741 ttgaaacgtt tggctacacc gtggccaatg actccgatga atttattaga agagttcaca
    16801 aatttcttat cacttgccat taggttattc ggtaatatct ttgccgggga agttgttaca
    16861 ggtttgattg ttcaactggc caattatcga gtttattggt ggccgatcgc tttcctagtc
    16921 aatatggcgt ggacagcctt ttcagtcttt atttcctgca tacaggcttt tgttttcaca
    16981 aaactaacag cgacctatct aggaaagaaa gttaatgaat cagaagaata aggaaggaga
    17041 acaaacgaat gtcaatcaca tttggtgaac tcgttgggaa ttttattcta gtaacaggtt
    17101 ctgtaatcgt cttgttactc ttgatcaaaa aattcgcttg gggtgcaatt gaatcgattt
    17161 tacagacacg ctcacaacaa atctctcgag atattgatca ggctgagcaa tcacgtctaa
    17221 gtgctcaaca gttagaggca aaaagtcaag ctaacctaga tgctagtcgt tcacaagcaa
    17281 gtaaaatcat tagtgatgcc aaagaaattg gtcaattaca aggtgataaa ttggtggcag
    17341 aagctactga tgaagcaaaa cgcttgaaag aaaaagcgtt gacagatatt gaacaaagca
    17401 aatcagacgc tatttcagca gtcaaaacag aaatgtctga tttaacggtt cttttagcgg
    17461 aaaaaattat gggagccaat cttgataaga cggcgcaaag ccagcttatt gacagttatc
    17521 ttgatgactt aggagaagct taatgaccaa aaaagaacag gctcttatcg agcaatatgc
    17581 aaaaagcctt gttgaggtgg caagtgaaca tcattctctt gatgccttac aagctgatgt
    17641 gcttgcgatt ttagagacgt ttgtaacaac taatcttgat caaagtctat caagtctagc
    17701 tgttccgcat gctgaaaaaa taaaattgct aaccttatta aagggaaata attctgttta
    17761 tatgaataat ttcttgaatc tcattttaca aaacgaacgt gaagcttatt tgtatcaaat
    17821 gcttcaggct gttttaaatg aaattgcaat agtttcaaat cagtatgatg tgacagttac
    17881 ctcatcacta cctttgactg aggagcaaaa aagccgtgtt cgagcagttg ttgcaaagaa
    17941 atttgctgta acagcgggtc gtttaattga aaaagtagat ccttcgctta ttggaggatt
    18001 tattatcagc gtcaataata aagtaattga taccagtatt cgtcgtcaat tgcaagcatt
    18061 taaaatgaat ttaaaataga aagtggtgtg acttttggca attaatgcac aagaaattag
    18121 cgctttaatt aaaaagcaaa ttgagaactt ccagccaaat ttcgatgtca cagaaactgg
    18181 gatcgttacc tatattggtg acggtattgc acgtgcccgt ggattagata atgccatgag
    18241 tggtgaactt cttgaatttg aaaatggtgc ctatgggatg gctcaaaacc ttgagtcaaa
    18301 tgatgtgggt attattattc ttggtgattt ttcagcaatc cgtgaaggag atgtggttaa
    18361 gcgcaccggt aaaatcatgg aagtaccagt tggtgaagct ctcattggac gtgtggtaaa
    18421 cccacttgga caaccagttg atggcttggg agatattgaa acaactggct ttagaccagt
    18481 agaaacgcca gctcctggtg ttatgcagcg taaatccgtt tctgaaccct tacaaactgg
    18541 attaaaagca attgatgctt tggttccaat tggtcgtggg caacgtgagt tgattatcgg
    18601 agaccgtcaa acaggaaaaa catccgtagc tattgatgcg attttgaacc aaaaaggtca
    18661 agacatgatt tgtatctatg tggctattgg tcaaaaagaa tcaaccgttc gtacacaagt
    18721 tgaaaccctt cgccgttacg gtgccttgga ttatactatt gttgtgacag cgtcagcctc
    18781 acaaccatca ccattgctct ttatcgctcc ttatgcgggt gttgccatgg ctgaagaatt
    18841 tatgtaccaa ggcaagcatg tcttgattgt ctatgatgac ttatcaaaac aagcggtggc
    18901 ttatcgtgaa ttgtctctct tgcttcgtcg tccaccaggt cgtgaggctt acccagggga
    18961 tgttttctac ttgcatagcc gtcttttgga acgctctgca aaagtttctg atgatttagg
    19021 tggaggttct atcacagctc taccatttat cgaaacacag gccggagata tctctgcata
    19081 tattgcgact aacgttattt cgattacaga cggacaaatc ttcttgcaag agaacctctt
    19141 taattcagga attcgtccag cgattgatgc aggatcatct gtctcacgtg taggtggttc
    19201 agctcaaatt aaagcgatga aaaaggttgc tggtactctt cgtttggatt tggcttccta
    19261 tcgtgaatta gaagccttta cccaatttgg ttcggacctt gatgctgcaa cacaagcaaa
    19321 acttaatcgt ggtcgccgta cggttgaaat cttgaagcaa ccattgcata aaccgttacc
    19381 tgttgaaaag caagtcgtta ttctttatgc ccttactcat ggtttcttag atgatgttcc
    19441 tgtagatgat attttggctt ttgaagaagc tctttacgac tactttgacg ttcattacaa
    19501 tgatttattt gaaactatcc gtaccacaaa agaccttcct gaagaagctg cccttgatgc
    19561 cgctattaaa gcgtttaaag aacactcaaa ctttaagtca tagagggagg atactagtat
    19621 ggcaggctct ctaagtgaaa ttaaagctaa aattatttca actgagaaaa caagtaaaat
    19681 cactagtgcc atgcgtatgg tttcttctgc aaaacttgtt aaatctgagc aagcagctcg
    19741 tgattttcaa atttacgcct caaaaattcg ccagattact acagatttat tgaaatcaga
    19801 attaaccata ggatctgata atccgatgtt ggtgtctcgt cctgtcaaaa aaacaggcta
    19861 tattgtcatc acgtctgata aaggacttgt tggaggttac aattcaaaaa tcttgaaatc
    19921 tgttatggat atgattacag agtaccatgc tgatggtgac tatgaaatca tttctattgg
    19981 tagtgttggt tcagacttct tcaaagcaag agggatgaat gtggcttttg aacttcgtgg
    20041 acttgcggat caaccaagtt ttgaacaagt gagacaaatc atttcacaat ccgttgacat
    20101 gtttgtcaat gagatttttg atgagttata tgtctgttac aatcaccatg tgaatagctt
    20161 aaccagccaa gtccgtgttc aacagatgtt gccaatttct gacttggttg ctgatgaagc
    20221 agcagaagaa ggtgttactg ggtttgaatt ggaacctaat cgtcatgata ttttagatca
    20281 attgttacct caattcacag aaagtttaat ttatggggct atcattgatg ctaaaacggc
    20341 tgaacatgca gcaggtatga ctgctatgca gacagcgaca gataacgcta agaatgtcat
    20401 taacgatttg accatccaat ataaccgagc tcgtcaagca gcaattacac aagaaattac
    20461 tgaaattgtt gcaggagcaa atgcactaga ataaaaaatg acgctgacta gcgattaggt
    20521 tattgtcagc attcaatttt atcaatcgag ataaaatgac ttatgggact tttctattga
    20581 aagactgctc ttttcagtat gaaagaagtt agcaagacta actaagccct gactatcgaa
    20641 tataaggaga aatgaatgag ctcaggcaaa attgctcagg ttgttggtcc agtagtagac
    20701 gttatgtttg ctagtgggga caaacttcca gagattaata atgcattgat tgtttataaa
    20761 gatagtgata aaaagcaaaa aatcgtcctt gaagttgctc tggaacttgg tgacggtatg
    20821 gtgcgaacaa tcgctatgga atcaactgat gggcttacac gtgggttaga agttcttgac
    20881 actggtcgtg cgattagcgt accagtaggt aaagaaactt tgggacgcgt ctttaatgta
    20941 cttggagaaa ccattgactt ggaagaacca tttgcagaag atgttgaccg tcagccgatc
    21001 cataaaaaag caccatcgtt tgatgaatta tcaacatcat cagaaattct tgaaactggt
    21061 atcaaggtaa ttgaccttct tgccccgtac cttaaaggtg gtaaagttgg actttttggt
    21121 ggtgccggag ttggtaagac tgtccttatc caagaattaa tccacaatat cgcccaagaa
    21181 cacggaggta tttcagtatt taccggtgtt ggtgagcgaa cacgtgaagg aaatgacctt
    21241 tactgggaaa tgaaagaatc aggcgttatt gaaaaaaccg ccatggtttt tggtcagatg
    21301 aatgagccgc ctggggcacg tatgcgtgta gcccttactg gtttaaccat tgctgagtat
    21361 ttccgtgatg tagaaggcca agatgttttg ctctttattg ataatatctt ccgtttcact
    21421 caggcaggtt cagaagtatc agccctctta ggccgtatgc cttctgctgt tggttaccaa
    21481 ccaacccttg ctactgaaat ggggcaattg caagaacgga ttacatcaac tcaaaaagga
    21541 tctgttacat ctatccaagc gatttatgta ccagcagatg attatactga ccctgcgcca
    21601 gcaacagcat ttgctcactt ggattcaaca actaaccttg aacgtaaatt gactcaaatg
    21661 ggtatttatc cagccgttga cccattggct tcaagttcac gggccttatc acctgaaatt
    21721 gttggtgaag agcactatgc tgtggcaaca gaagttcaac gtgtgcttca acgctaccgt
    21781 gaattacaag acatcatcgc tattttgggg atggatgaat tgtcagatga agaaaaaaca
    21841 ttggttggac gtgcgcgtcg tatccagttc ttcctctcac aaaattttaa cgttgctgaa
    21901 caatttaccg gtcttcctgg ttcttacgtg ccagttgctg agacagttcg cggctttaaa
    21961 gaaattcttg aaggaaaata cgatcacctt ccagaagatg cctttcgttc agttggtcca
    22021 atcgaggatg tgattaaaaa agccgaaaaa atgggctttt agtgaggtga tgccatgaca
    22081 caaatgactg ttcaagtggt aacgccagat ggaatcaaat atgatcacca tgctaaatgt
    22141 atttctgtaa caacaccaga tggggaaatg gggattttac ctaatcacat caatttaatt
    22201 gcacccttgc aagttcatga aatgaaaatt cgccgaggtg gtgaagatga aaaagtggac
    22261 tggattgcta tcaatggtgg tattattgaa atcaaggata atgtggttac cgttgtcgct
    22321 gattctgcag aacgtgaccg tgatatcgat gtcagccgag cagagcgagc aaaactaaga
    22381 gcagaacgtg aaattgcaca ggctgaaacg acccacaaca ttgatgaagt tcgtcgtgcc
    22441 aaggttgcct tgcgccgcgc tttgaatcgt atcaacgtta gtaaaaaata agtggtgttg
    22501 ataaaagaca aggataagta agaaaggttt ttaacctatt attttgtttg ctgagtcttt
    22561 ttaacatcag tttctgagag tttgaccata ctaccttctc taaacacgtt attattgttg
    22621 agaggagtta tatgggggaa ctcttttttg tatccacgtt gttagtagaa actcagtaat
    22681 gacgcttaat gtattttcag gctatcaact tagtcagaga ggatgtcaat ttaattgata
    22741 agttggacgg atcaagatgg tatgttataa taatcctatg gaattattaa tgaagatcat
    22801 tgccttttcg tgtcatttat tttttattgg ccttagttac caattattga ttagtgtgat
    22861 tgactggaca aaatttagtc attatcatcc agaaaatctt ggccggctac gactttttgt
    22921 ctttttatta gctactgccc tagggtattt ggtgagccat tgtatgctgg aattgcttca
    22981 aattagccag acgctctttt ttgagttccg ctaatactgg aataaaagaa gtatggtata
    23041 attttactac gactaagaga tagttaaggg agaaaattgt ggataaaata atcattgaag
    23101 gtggtcaaac acgcttagaa ggagaagttg ttattgaggg tgctaaaaac gcagttcttc
    23161 ctttactggc agcatctatt ttaccttcaa aaggaaaaac aattcttaga aacgttccta
    23221 ttctatctga tgtttttact atgaataacg tggtacgtgg tttagatatt cgtgttgatt
    23281 ttaatgaagc agctaacgaa atcacagttg atgcctcagg acacatttta gatgaagccc
    23341 cttacgagta cgtgagccaa atgcgtgcct ctattgttgt tttaggaccc attttggcac
    23401 gtaatggcca cgcaaaagta tcaatgcctg gaggctgtac gattggcagt aggcctatta
    23461 atttgcactt aaaaggatta gaggctatgg gggcaacgat tactcaaaaa ggtggagata
    23521 ttactgctca agcagatcga ctgcaaggtg ccatgattta tatggacttc ccatctgtag
    23581 gagctaccca aaacttgatg atggctgcca ctttagctga tggtgtgacc actattgaaa
    23641 atgctgctcg tgagcctgaa attgttgatt tagctcaatt tttgaataaa atgggagcta
    23701 gaattcgtgg tgctggaaca gagacgttaa cgataacagg cgtcacgcat ttacgaggcg
    23761 tagaacatga tgttgttcaa gatcgtatag aagccggtac atttatggtt gcagcggcaa
    23821 tgacttcagg taatgttttg attagagatg ctgtttggga acataatcgt ccattgattt
    23881 caaaattaat ggaaatgggt gtttctgtaa cagaagaaga atacggtatt cgcgttcaag
    23941 caaacacgcc aaagctcaaa cctgtaacgg ttaaaacctt gcctcatcca ggttttccaa
    24001 cagacatgca agctcaattt acagctttaa tggcagtggt caatggagag tctactatgg
    24061 ttgaaactgt ctttgaaaat cgatttcaac atctggaaga aatgcgacgc atgggcttac
    24121 aatctgaaat ccttagggaa actgccatga ttcatggtgg aagacaactg caaggtgctc
    24181 ctgtgatgtc aacagattta cgtgccagtg ctgcccttat cttgacaggg attgttgctc
    24241 aaggagttac aatagttaat aatttggttc atttagatcg tggctactat caatttcatg
    24301 aaaaattagc aaagcttgga gctactatta gtcgtagcag tgaggtctag cttatgacaa
    24361 atggtttaaa atatgtctta gaacaaatgt tattactttt cataattgct gccttggcgt
    24421 gtcttttttt agccattgga cttatgattg gttatagttt tatgggagat ggccatagtc
    24481 catggcatat tttatctatg gataagtggg cagagttagt gaataaattt actggaaagt
    24541 aggccttgcc tactttttat agcatctgag aggaagtatg ttaacaagga aaaaacgaaa
    24601 aagggtgcaa gagcaaaagg ttcctaaaag agccaacgct ttacttgcta agtcaacccg
    24661 gcaatatcaa gaccgttcat aacttaagaa aggttaccgt tcatttaagc cagcaggttg
    24721 gcaccgattg caccacttaa aaggaagtta tgatcacgcg gttgatagag ggcatttgct
    24781 aggttatgct ttagttggtg gactgaaagg ttttgatgct tctactggta atcctgataa
    24841 tattgccact caactaagtt gggctaatca agcaaataaa ccctactcga caggtcagaa
    24901 ttactatgaa ggtttagtac gtcgtgcttt ggataagggg catcgcgtcc gctaccgtgt
    24961 caccctactt tatgatggtg ataatctact agccagcggt agccatttgg aggctaaatc
    25021 ctctgatgac agcttggctt ttaacgtgtt tgttccaaat gtccaagcag gattgaccgt
    25081 tgactatcgg acgggacaaa tagctgtcaa caattgcctt ttgcttatct cttcagttgc
    25141 tgtgatttta tcatacagtg ataaaagat
//
LOCUS       DAUCXI010000027        24252 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.027, whole genome shotgun sequence.
ACCESSION   DAUCXI010000027 DAUCXI010000000
VERSION     DAUCXI010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24252
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.027"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            26..2512
                     /gene="gyrA"
                     /locus_tag="VGY43_001168"
     CDS             26..2512
                     /gene="gyrA"
                     /locus_tag="VGY43_001168"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEQ4302355.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIDEINTDRENSISKNKDN"
     gene            2532..3281
                     /locus_tag="VGY43_001169"
     CDS             2532..3281
                     /locus_tag="VGY43_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEQ4302356.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYNQVST"
     gene            3365..3778
                     /locus_tag="VGY43_001170"
     CDS             3365..3778
                     /locus_tag="VGY43_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ4302357.1"
                     /translation="MKLNAIHHVAIIVSDYNLSKNFYVNKLGFEIIRENYRPDKHDYK
                     LDLSCGRIELEIFGKVTSDPYYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGILVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
     gene            4392..4766
                     /locus_tag="VGY43_001171"
     CDS             4392..4766
                     /locus_tag="VGY43_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302358.1"
                     /translation="MTQKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKDSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEESLGQAKEKVEGIGEATSQ
                     TIQSKMEKLTSDKTDAADDDEK"
     gene            complement(4816..5727)
                     /locus_tag="VGY43_001172"
     CDS             complement(4816..5727)
                     /locus_tag="VGY43_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEQ4302359.1"
                     /translation="MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEVITPKN
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIKQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGDFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAISIIVPTED"
     gene            complement(5844..6494)
                     /locus_tag="VGY43_001173"
     CDS             complement(5844..6494)
                     /locus_tag="VGY43_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEQ4302360.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(6491..6931)
                     /locus_tag="VGY43_001174"
     CDS             complement(6491..6931)
                     /locus_tag="VGY43_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEQ4302361.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLSQEVTQ"
     gene            7150..7998
                     /gene="ylqF"
                     /locus_tag="VGY43_001175"
     CDS             7150..7998
                     /gene="ylqF"
                     /locus_tag="VGY43_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEQ4302362.1"
                     /translation="MAMIQWFPGHMSKARRQVQENVKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIQRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFREYY
                     PNRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GDMDAD"
     gene            7988..8779
                     /locus_tag="VGY43_001176"
     CDS             7988..8779
                     /locus_tag="VGY43_001176"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEQ4302363.1"
                     /translation="MPTSIKAIKESLEAVTSLLDPLFQELATDTRLGVQKALKSRQKA
                     IQAELAEEERLEAMLSYEKALYKKGYQAIAGIDEVGRGPLAGPVVAACVILPKYCKIK
                     GLNDSKKIPKAKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     GQLTQPDYLLIDAMTLDIAISQQSILKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            8844..9680
                     /gene="dprA"
                     /locus_tag="VGY43_001177"
     CDS             8844..9680
                     /gene="dprA"
                     /locus_tag="VGY43_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEQ4302364.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIISGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            9786..11915
                     /gene="topA"
                     /locus_tag="VGY43_001178"
     CDS             9786..11915
                     /gene="topA"
                     /locus_tag="VGY43_001178"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEQ4302365.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGPLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDG
                     LFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEVFLVSKVDKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFISNRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPEAIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVIFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMEEGENVKKVSTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEEWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            complement(11990..12874)
                     /locus_tag="VGY43_001179"
                     /pseudo
     CDS             complement(11990..12874)
                     /locus_tag="VGY43_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354842.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            12887..13453
                     /locus_tag="VGY43_001180"
                     /pseudo
     CDS             12887..13453
                     /locus_tag="VGY43_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631865.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
     gene            13468..14460
                     /locus_tag="VGY43_001181"
     CDS             13468..14460
                     /locus_tag="VGY43_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HEQ4302366.1"
                     /translation="MKLKLYNVRGEEAVLAKKWADDNGIEISLTESSLTPETVKEAEG
                     FDGIANAQIGPLDDAIYPLLKEMGIKQIAQRSAGVDMYNLDLATENDIIITNVPSYSP
                     ESIAEFTVTIALNLIRHVELIRENVKKQNFTWRLPIRGRVLGDMTVAIIGTGRIGLAT
                     AKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDADLVSLHMPPTAENTHLFNA
                     DLFKSFKKGAILMNMARAALIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQE
                     ITDSLFKALINHPKVIYTPHAAYCTDEAVKNLVEGALNATVEIIKTGTTTTRVN"
     gene            14565..15230
                     /locus_tag="VGY43_001182"
     CDS             14565..15230
                     /locus_tag="VGY43_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HEQ4302367.1"
                     /translation="MTYIALIGDIIQSKQLTDRSKVQKTLAAYLDDLNKTFAPYIISK
                     LSLTLGDEFQGLFQVDTPIFHLIDLINHHMDIPIRFGVGVGSILTDINPDISIGADGP
                     AYWHAREAIRYIHQKNDYGNTTLALRTGHHNQDDVLNSLLAAGDAIKANWRASQWEIF
                     DTLLDLGIYEEYFDQQRLGKQLSLSSSALSKRLKSSHVKIYLRTRQSALNCLKQIKEE
                     TDD"
     gene            15223..15939
                     /locus_tag="VGY43_001183"
     CDS             15223..15939
                     /locus_tag="VGY43_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEQ4302368.1"
                     /translation="MINGVSHYLAQTPTLTLFLICHVLSDYQLQSQQVADLKEKHLTY
                     LGYHLIGVSIPLICLTLIIPQAWLMSLLVMISHALIDWLKPKMANSLKWKREWIFLLD
                     QCLHIAISSFAGLRLAGVTLPNWLPISILMTVLFILLITKPTNIVFKLFFSKYQPDQG
                     EKMDTIIGAGATIGILERIVIGVCMIMGQFASIGLVFTAKSIARYNKISESPAFAEYY
                     LIGSLFSILSVFIAAWICFF"
     gene            16090..17436
                     /gene="trmFO"
                     /locus_tag="VGY43_001184"
     CDS             16090..17436
                     /gene="trmFO"
                     /locus_tag="VGY43_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEQ4302369.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAKSVTAELENHPLIEVIRDEITEIPNDAITVIATGPLTSDALAEKIHAVNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPL
                     NAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            17589..18995
                     /locus_tag="VGY43_001185"
     CDS             17589..18995
                     /locus_tag="VGY43_001185"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HEQ4302370.1"
                     /translation="MIQFGGFSMQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTIL
                     DKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTRLQMLLRGQNLLGYRHY
                     ADDIVDKFISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVH
                     TLNYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSG
                     ISQMTYLATVEAGADRIDTALSPFSEGTSQPATESMYLALKEAGYDITLDETLLEQAA
                     NHLRQARQKYLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLA
                     EVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPV
                     NEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFL
                     TTKYQTDDVIKVTAFIKA"
     gene            19038..19352
                     /locus_tag="VGY43_001186"
     CDS             19038..19352
                     /locus_tag="VGY43_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302371.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            19352..19702
                     /locus_tag="VGY43_001187"
     CDS             19352..19702
                     /locus_tag="VGY43_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="HEQ4302372.1"
                     /translation="MKRYEVTVNGQVYEVSLRELADGETVEVSRPAAPATEKEMNANA
                     AGGGIQVKAPMSGTVLSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            19712..20842
                     /locus_tag="VGY43_001188"
     CDS             19712..20842
                     /locus_tag="VGY43_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ4302373.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVENLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKIMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKIGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(21042..21926)
                     /gene="citG"
                     /locus_tag="VGY43_001189"
     CDS             complement(21042..21926)
                     /gene="citG"
                     /locus_tag="VGY43_001189"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEQ4302374.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFM
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGRFSKEDTLAICRLVKPMTAHLIQTDLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(21919..22614)
                     /locus_tag="VGY43_001190"
     CDS             complement(21919..22614)
                     /locus_tag="VGY43_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ4302375.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKKTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(22772..24175)
                     /locus_tag="VGY43_001191"
     CDS             complement(22772..24175)
                     /locus_tag="VGY43_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEQ4302376.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
BASE COUNT         7721 a         4422 c         4927 g         7182 t
ORIGIN      
        1 tgactagaaa aggagcattc cttaaatgca agatcgaaat ttaattgacg tcaatctgac
       61 aagtgaaatg aaaacgagtt tcattgacta tgccatgagt gtcattgtgg caagagcttt
      121 gccagatgtg cgtgatggtc tgaaacctgt gcatcgtcgt attctctatg ggatgaatga
      181 actcggtgtg acacctgata aaccgcataa aaaatctgct cgtattacgg gtgatgtcat
      241 gggtaaatat cacccgcatg gggattcttc tatttatgaa gctatggttc gtatggctca
      301 gtggtggagt tatcgccata tgcttgttga tggccatggc aattttggtt ctatggatgg
      361 tgatggtgct gccgctcaac gttatactga agcgcgcatg agtaaaattg cgcttgaatt
      421 attaagggat atcaataaaa ataccgttaa ttttcaagat aactacgatg gaagcgaaag
      481 agaaccagta gtattaccag ctcgctttcc taatttatta gtcaatggag cgacagggat
      541 tgccgttggg atggcaacta acattccgcc tcataatttg gcagagtcta ttgatgctgt
      601 caagatggta atggaacatc cagactgtac aacaagagag ttgatggaag tgatccctgg
      661 acctgacttt ccgactggtg cccttgttat ggggcgctca ggtattcata gggcttatga
      721 tactggtaaa ggttctatcg ttttacgctc tcgaacagaa attgaaacaa ctcaaacagg
      781 tcgggaacgt attgtggtta ctgaatttcc ctatggcgtc aataaaacga aagtgcatga
      841 acacattgtt cgtttagcac aagaaaaaag actagaaggt attacagcag ttcgtgacga
      901 atctagccgt gaaggagtgc gttttgttat cgagattcgt cgagaggcat ccgcgacagt
      961 tatcttaaat aacctcttta aattaacaag ccttcagacg aatttcagtt ttaatatgtt
     1021 ggctattgaa aatggtgtgc ctaaaatatt gtcactcaga caaatcattg ataattacat
     1081 tagtcatcaa aaagaagtta ttatacgtcg cacccgattt gataaagata aagctgaagc
     1141 cagagctcat attttagaag gcttactgat tgcccttgat catttagacg aagtgattgc
     1201 tattattcgt aacagcgaga cagatgtcat tgctcagaca gaattgatgt cacgtttcga
     1261 cttgtctgaa cgccaaagtc aagctatttt ggatatgcgt ttgcgtcgtt tgactggttt
     1321 ggaacgtgat aagattcaat cagaatatga tgatttgttg gccttgattg ctgacttatc
     1381 tgatatttta gccaaaccag aacgtattat cactatcatc aaagaagaaa tggatgagat
     1441 caagcgtaaa tacgctaacc cacgccgtac agaattaatg gtcggtgaag tcctttctct
     1501 agaagatgaa gacctaattg aagaagaaga tgttttgatt accttgtcaa ataaaggtta
     1561 tatcaagcgt cttgctcaag atgaatttcg tgcccagaag cgtggtggac gtggcgtcca
     1621 aggaactggg gtcaacaatg acgactttgt ccgtgaattg gtatcaacaa gtacccatga
     1681 tactttgctc ttctttacga attttgggcg tgtctatagg ttgaaagctt acgaaattcc
     1741 agaatatggt cgtacagcaa aaggtcttcc aattgttaat ctattgaaat tagaagatgg
     1801 tgaaaccatt caaactatta tcaacgcacg taaggaagaa acagcaggta aatccttctt
     1861 ctttacaacg aaacaaggca ttgtcaaacg tacagaagtt tcagaattta ataatatccg
     1921 tcaaaacggt ctccgtgctc ttaagttgaa agagggagat cagctgatta acgtcctttt
     1981 gacaagcggt caggatgaca ttatcattgg aactcattcc ggatattctg ttcgttttaa
     2041 tgaagcaagc atccgcaaca tgggccgatc agctacgggt gttcgcgggg ttaagcttcg
     2101 tgaagatgat cgcgttgttg gcgcgtcacg tattcaagat aaccaagaag ttcttgtaat
     2161 taccgaaaat ggctttggta agagaacaag tgctacagac tatcctacaa aaggtagggg
     2221 gggaaaagga ataaaaacag ctaatattac ccctaaaaat ggtcaattag ctggattggt
     2281 taccgtagat ggtacagaag atatcatggt gattacaaat aaaggtgtca ttattcgcac
     2341 aaatgttgca aatatttcgc aaacaggtcg tgctactttg ggtgttaaaa ttatgaaact
     2401 agatgctgat gctaagattg taacatttac cttggttcag cctgaagaca gtagtatcga
     2461 tgaaatcaat actgatcgtg aaaatagtat ttcaaaaaat aaagataatt aatcataaca
     2521 aggagtaaaa aatggtaaaa aaacaaaagc gtcgaaaaat aaaatccatg tcttgggcaa
     2581 gaaaactact aatagctgta cttttaattc taggtttagc attgcttttt aacaaaccta
     2641 tccgaaatac attaattgct cgaaactcta ataaatatca agtaacgaaa gtttcgaaaa
     2701 aacaaatcaa aaagaataaa gaggctaagt caacatttga tttccaagcc gtagagccag
     2761 ttagtacaga gagtgtcttg caagcacaaa tggcggctca gcaacttcct gttatagggg
     2821 gcattgccat accagagctt ggcattaatt taccaatttt taaaggttta ggaaatactg
     2881 agcttattta tggcgcagga acgatgaaag aagaacaagt tatgggagga gaaaataatt
     2941 attctcttgc cagtcatcat atttttggaa ttacaggttc atctcaaatg ctcttttcgc
     3001 cgcttgaaag agcacaaaat gggatgtcca tctatttaac agataaagaa aaaatttacg
     3061 aatacatcat aaaagatgtt ttcacggtag ctcctgaacg cgttgatgtt atcgatgata
     3121 cagctggtct caaagaagtg actttagtga cttgtacaga tatcgaagca acagaacgta
     3181 ttattgtcaa aggagaacta aaaacagaat acgattttga taaagcgccc gccgatgtat
     3241 tgaaagcttt taatcattct tataaccaag tatctaccta gatatatctt aaatataata
     3301 tttaaaaagt aggaccatag agaaaattta tctcatccta cttttttttg aaaggagaaa
     3361 tattatgaaa ctaaatgcca ttcaccacgt tgctattatt gtatctgatt ataatctgtc
     3421 aaaaaatttt tatgtgaata aactcggatt tgaaattatc agagaaaatt atcgtcctga
     3481 caagcatgat tacaaattag atttatcttg tggtcgtatt gaattggaga tttttggtaa
     3541 ggtgacaagt gacccctact atcaagctcc tcctaaacgt gtaagtcaac cagaatttaa
     3601 aagtgaggcc tgtggtttga ggcaccttgc ttttcgtgtt accaacattg agagttatgt
     3661 agatgatcta aagagcttag gaattctagt ggagcctatc aggcatgatg attacacagg
     3721 tgagaaaatg actttctttt ttgatccgga tggtttgcct ttagaattac atgaatagac
     3781 ttattaggtt aacgactgga tcgtgctata aaactcgtta aaaatagtta tttgttgtat
     3841 cttcatttgc ttgattaatc tcttttgatc gttaaatgat ttggttaact ttcaaagtga
     3901 agagcaattt ttggagtaat cttgtcgaag ttttttaata gaataactat agaaaaagca
     3961 aaatatttga cgataaactc ttacagtgtt ataatgacaa tataagttaa taactgtgtt
     4021 gtcactttgt tgaaatgttt tcgtattaat gtttttttat ctattacgat agataatttt
     4081 acttcaattt ttgattgaaa atactaaaat aagtgatgtg gtcactttga caaccattta
     4141 ttggtccttt tagataagac aattttgtgg ctcttcagtt gaaaggatgt gttgttgatg
     4201 ttagaggaaa caatcatgtt aaattaactc aggcttaaag accaaaaaag gagtgaagtc
     4261 tattatgaaa aaaagaaatt ttaaacttac agaaatgtta caattggttt tattagtggt
     4321 tcctgctgta aaacttgcta aaaaaatgtt taacgatagt aaaacaccgt ctaaaagaaa
     4381 gtaggtctac aatgactcaa aaaaatcatg gcgttttttg ggggttgttg cttggatcag
     4441 cagcagctag cattgcttac ttaagtttat cgtcttccaa aaaagatcaa ctcttgaaag
     4501 atagtgctaa aaaaatagat gatctcaacg cttacttgca agataaaagt aagcaagttc
     4561 tggatgcagt atcggaaaaa gtacaagaat ccaaagatgc tgttgaagtt tatggtggta
     4621 ttgccgcaga aacagttgaa gaatctttgg gacaggctaa agaaaaggta gaaggaattg
     4681 gcgaagctac tagtcaaact atccaatcta aaatggaaaa actcaccagc gataagacag
     4741 atgctgctga tgatgatgaa aaataggttt taaaatacct ttaagataag acaaaaagtg
     4801 ccattaggca cttttttaat cttctgttgg aacaataatc gaaatggctt ttggaatgat
     4861 atctaattga atgggcagat agtcactttt atccccatca atcctggtac gtggtaatat
     4921 cgcttgtttt ttagcttgtg gtagtaagct aagcgtattg gcttgaaaat gactgatttc
     4981 ctctgctttg gaaaaatcac cctgtttaaa atcattaata tgccataaaa atttaaagaa
     5041 agagactttt ttcatggtat aaacttggaa atagccatcg tcagcttgag caccaggaga
     5101 aaaagaagga aaaccagcaa tggtatttgt catcgtgatt aagagaaact tcgtttttag
     5161 gtgaatacga tggttgtggc taattaaaga gatggcatag ctgcgatttc gtttcagtat
     5221 tcgaatacta tcttttaaaa atgctagagg accaaagcgt cgtttttcct cagccgttac
     5281 gtcggcagca atatcagcta gtaatcctaa ggttaaactg gaaatcatgt attgctggtt
     5341 agctttgcaa atatcaactt gtttgatttg tcccgtcaag atagtatcca acgcctcagt
     5401 aatttgtaaa gggatatgca tagccttggc aaaattattg actgtccctg agggcactaa
     5461 gcctattaaa caatgagctc ctccttcata gatgccaccg atgattttat ttagtgtccc
     5521 atcgccacca agagggataa ccaagtcaat cttgtcctta gcagcttgtt ttgctaattg
     5581 aaaagcctgg tcagcatttt taggggtaat aacttctaca gaatcttcgg aaaaaccatg
     5641 ttggcaaaaa tagtctttga cttgcccagc aagttgatct tctttctttc cagaattagg
     5701 attgtaaaaa atccgaacgg ttttcatcag gtctctcctt tgacagctta ttacttgcta
     5761 tccattatac cacttctaag agttgatgtc ttacatcaac tcatcacatt aagcctctca
     5821 atcagtctga gcatctattt gtcttaaagc ataaagaaag tgatagcgat aaattggagg
     5881 gcagaggcca ataaaataaa gagatgccaa atcatgtgga agtagggtct ttttttggca
     5941 taaaataccg ctccaatggt ataagacaag ccaccaaata acatgagaag accaaaagca
     6001 agactagttt tttgaatgat gactggcaag ataaacacaa cgagccagcc cataacgata
     6061 taaagcatca aactgaattt ttcattgata cgtttggcaa aaattttgta taaaatccca
     6121 aaaagcgtaa tgccccactg caaaacaata atgatatagc ctagccaacc agaaacaagg
     6181 gataaggcaa caggtgtata acttcctgcg atagcaatgt aaatcatact gtgatcaata
     6241 atgcgtagaa tgtatttgtg aaccgaacca taagccatgg agtggtaaat cgtagaggac
     6301 aaaaacatca aaaagagact gatgacaaag atggagatac caatagcggc tttaaggtca
     6361 taagtttgat aagcatagct ggctgaaata ggaagtagaa tgagcatagc aaatgctccg
     6421 atagcgtgtg tcacgctgtt tgctacttcc tcactaaaag ataagggtaa actttgttta
     6481 aaggtttggt tcattgggtc acctcctgtg ataaataaat agttttgtgg taatctttga
     6541 ccgtttgaca ggcaacctgc acaatcggtg gaatgtcctc ctcaatggga gccttctgat
     6601 tccaacaggt tacaaaagta ttgtaaagac tttcagaatc agcctgtgcc tgaagttcct
     6661 ccaatacgcg actaatatct tgaataggaa ataccgtttt aaacaaactg atggcaatta
     6721 agcgcgctag ttgttgcttt tggtattttt tcttgatagg tttagtcaca tacccatgct
     6781 tgacgtaatt attaatcata gatgccgtta gtgatttatt atctgacact tctgaaaaat
     6841 cagtgcactg gttgacataa agtaagactt gatccaaata taagtctaaa tcagggaggt
     6901 ccttccaata aggtaatgat ggaaaaatca tagttttgtc tctctatcta gttttgataa
     6961 ctagattata cgattaatga aaacttattg caagcaaaaa ctgtaaagac ttaaaagagg
     7021 aaagtagaaa tggcgaagtg aagctaatca tgctataatg ttaaagaatt gattgggata
     7081 gatgccttct gtcgcaatca gactatttta tcacgaagaa gatgatgcta cgaaaggaat
     7141 gatacactca tggcaatgat tcaatggttt cctgggcaca tgtccaaagc cagaagacag
     7201 gttcaggaaa atgtaaagca tgttgacttt gtaactattt tagtggatgc acgcttacca
     7261 ctttctagtc aaaatcccat gcttacaaaa attgttggtg ataaacctaa attaatgatt
     7321 ttaaataaag ctgacttggc agatgcaact cgaactaaag agtggaaggc ttattatgaa
     7381 agtcaaggta ttaaaacatt agccatcaat tccaaagaac aatcaacggt taaaaaagta
     7441 acagaagcag ccaaggaact catggctgat aaaattcaac gcttgcgaga gcggggcatt
     7501 caaaaagaaa ccttgcgaac catgattatt ggcattccaa atgctggtaa atctacctta
     7561 atgaatcgct tggctggtaa gaaaattgct gtagttggca ataaacctgg tgtgactaaa
     7621 ggacaacaat ggttgaagtc caataaggaa ttggaaattc tagacactcc tggtatttta
     7681 tggccaaaat ttgaggacga attggtgggc ttaaaattag ctttaacagg tgctatcaag
     7741 gaccaattac taccaatgga tgaagtgact atctttggct tgaattactt tagggaatac
     7801 taccctaatc gtttaaccaa acgttttaag aatattcctc ttgaggaaga agctcctgaa
     7861 atcattatga ccttgacacg ccaacttgga tttaaagacg attatgaccg tttttacact
     7921 ttattcgtta aggaagttcg tgatggtaaa ttaggtcaat acaccttaga tcaggtggga
     7981 gatatggatg ccgactagta ttaaagctat taaagaaagc ttagaggccg ttactagcct
     8041 cttagacccc ctctttcaag aattggcaac cgacactagg ttaggcgtcc aaaaagctct
     8101 aaaaagccga caaaaggcta ttcaggccga gttagcagaa gaagaacgat tagaagccat
     8161 gctttcttat gaaaaagctc tttataaaaa aggttatcaa gccattgcag gtattgatga
     8221 ggtgggacgt ggtcccttag caggtcccgt tgtggcagct tgtgtgattt tacctaagta
     8281 ttgtaaaatt aaaggcctta atgattctaa aaaaatccct aaagctaagc atgagaccat
     8341 ttatcaggca gtgaaagaaa aggctttggc tatcggtatc ggtattattg acaatcagct
     8401 gattgatgag gtcaatattt atgaagcaac caaactagct atgctagaag ccattaaaca
     8461 gttggagggc caactcacac aaccagatta tctcttgatt gatgccatga cattggatat
     8521 tgctatttcg cagcagtcta ttcttaaagg cgatgccaat tccttgtcta ttgcagcagc
     8581 atcaattgta gctaaggtca ccagagatca gatgatggct aactatgatc gcatttttcc
     8641 tggttatggc ttcgctaaaa atgcaggcta tggcaccaaa gaacatttac agggattaaa
     8701 agcttacggc ataacgccta tccatcgtaa aagttttgaa cctgttaaat ccatgtgctg
     8761 cgattcaact aatccttaaa aagttctgtt tttagcagaa tttttttctt ttttacgaat
     8821 aaatgaagta aggaggtaac ttagtgaatc attttgaact ttataagcta aagaaagctg
     8881 gactgactaa taaaaacatt ctcaatattc ttgactacca aaaacaacag gaaaaatcgt
     8941 tgtcacttcg agatatggcc gttgtttctg gctgtaagca tccgtctcac tttatagaag
     9001 cctataagca gttagatatt caaaaattaa aaatggaatt taaacaattt cctagtattt
     9061 ctatcttaga taagcattac ccaatggcat tgaaagaaat atacaatcca cctgtcctct
     9121 tgttttttca gggaaattta gaccttcttg agaaacctaa attagccatt gtcggctcca
     9181 gacgctcaag cgataccgga gtaaagtctg tccgtaaaat tcttaaagaa ctcgggaacc
     9241 gttttgtgat tattagcgga cttgctcgag gtatcgacac tagtgctcat ttagcctgcc
     9301 ttaaaaatgg gggacaaacc atcgctatta ttggaacagg gttggatcgc ttttacccta
     9361 aagaaaatag ggagttgcaa actttcttag ggaaaaatca tcttgtgata acagaatacg
     9421 gtccaggaga agaagcttta tcttatcact ttccagaacg gaatcgtatt atcgcaggcc
     9481 ttagccgagg tattcttgtc gttgaagcaa aaaatcgttc aggttccttg attacttgcc
     9541 aaattgggat agaagaaggc cgagacattt ttgctgtccc aggaaacatt ttggacggga
     9601 aatccgaagg ttgccttcag ttaattaaag agggagcaac atgcgtcacg tcgggcatgg
     9661 atatcctttc agagtactaa aaaagttaaa gtttcttcct atatagcatt ttttattgac
     9721 agtttcttaa aaatgggata ttatgctata agctttaaac aaactgttat aggaagtgtg
     9781 tcgaattggg aacaaaaact acaactaagc caaaaacggg tactaaaaag tccaccacta
     9841 aaaagaaatc aacagcgaaa aaaaatctcg ttattgttga atcacctgcc aaagctaaga
     9901 ctattgaaaa atatcttgga cgcagttata aagttgttgc ttcggtagga catattcgtg
     9961 acttaaaaaa atcgtctatg tctattgatt ttgataataa ttatgagcca caatacatta
    10021 atatccgtgg taagggaccc cttatcaatt ctttaaaaaa agaagccaaa gctgctaaaa
    10081 aagtttattt agctagtgac ccggatcgtg agggagaggc tatttcttgg catttgtcac
    10141 atatcttagg acttgatcct caagataata accgagtggt ttttaatgaa attacgaaag
    10201 atgcagttaa acatgccttt gtggagcctc gtcagattga tatggacttg gtagattctc
    10261 aacaagcacg tcgtgttttg gaccgtattg tgggatattc catttcacca attctttgga
    10321 aaaaggtcaa aaaaggactt tcagcaggac gtgtccagtc ggttgcttta aaactcatca
    10381 ttgaccgtga aaatgacatc aaagcatttg ttccaaagga atactggtct attgatggtc
    10441 tttttaaaaa aggaactaaa aagtttcaag cgacttttta cggtattaat ggcaaaaaaa
    10501 caaagcttga taataacaac gatgtcaaag aggtattagc aaagctaaca aatgaagttt
    10561 ttcttgtcag caaggttgac aagaaagagc gacgtcgtaa tgctccctta ccttacacaa
    10621 catcatctct acaacaagat gctgctaata aaatcaattt cagaacgcgt aaaaccatga
    10681 tggtagccca acaactgtat gaggggattc atttaggaga aaacggaact caaggtttaa
    10741 ttacctatat gcgtactgat tctacacgga ttagtcctgt agcgcaaaat gatgctgccc
    10801 aatttatcag taatcgtttt ggagctaatt attctaaaca tgggaatcgt gtcaaaaata
    10861 ccagtggtgc ccaagatgct cacgaggcta ttcgtccatc tagcgtcaat catacaccag
    10921 aagctattgc caaatacctt aacaaggatc agttaaaact ttatacgctt atttggaatc
    10981 gttttgtggc tagccaaatg acagcagctg tttttgatac cgtaaaggtg aacttggagc
    11041 aaaatggcgt gatttttgtt gccaatggaa gccaaatgaa atttgacggt tatatggctg
    11101 tttataatga ctcagataaa aacaaaatgt tacctgaaat ggaagaagga gaaaacgtta
    11161 aaaaggtatc aacttctcca gaacagcact tcacgcaacc tccggctcgc tactccgaag
    11221 caactctgat taaaacttta gaagaaaatg gggtcggtcg accatcaact tatgccccaa
    11281 ccttagaagt gattcaacgc aggtactatg ttaaattatc tgctaagcgc tttgagccaa
    11341 ctgagcttgg ggaaattgtc aacaagctta ttgtcgaatt tttcccagat attgttgatg
    11401 ttgcctttac tgccgagatg gaaggtaagc tagatcaagt tgaaatcggt gaagaagaat
    11461 ggcaacatgt catcgatcaa ttctatcaac cctttgtcaa ggaattgaat aaggctgagt
    11521 ctgaaattga aaagattcaa atcaaagatg agccagctgg ttttgactgt gatgtttgtg
    11581 gccacccaat ggtcattaag ttaggacgtt ttgggaaatt ttacgcgtgt agcaacttcc
    11641 cagagtgccg taatacaaaa gccatcacta aagaaattgg tgttacttgt ccggtttgtc
    11701 ataaaggaca agttatcgag cgtaaaacca aaaaaaatag gatattttat ggttgtgatc
    11761 agtatccaga ttgtgagttt atctcgtggg atttacctat tggacgtgct tgccctaagt
    11821 caggtgacta tcttattgag aaaaaagttc gtggtggcaa acaagtaatg tgtagcaatg
    11881 agacctgtga ttacaaggaa gaaaaaatta aataaaaaaa gaattggaac tccttgtctt
    11941 gttccaattc tttttttatt tacaaaggta tttttaacta caaaaatcgc tagttcgttt
    12001 ttaaaaggct taaaaattcc tcaataactg gactgaaact cgcatcatct cggtaagcaa
    12061 tcccaatagg gtaaaaatta tttttatctt gcaaaggaat ccaaactaag ttatctacct
    12121 gattaagact ctcaaaatca ctcgggagga tagtcaaggt atttaaatcg tgcaaactat
    12181 gaataagaac ttcccaatca ttgtgtttaa agacaatatc tggttcaaaa ccgagagctc
    12241 ggcattttct aggaagcatt tcgcctaaca tgtagtgatc gtttaaagaa gcaatcttat
    12301 agccttttaa atctttaagt tttaactgag gatgttgcgc caaagggtgc tgtttgagga
    12361 gaacgatact gaccttatag ccttttgtgg acgtttgtaa tagctcaatg gtaatatcct
    12421 tttgaatact tagaaaggag aggagaccaa tatcgatttt tccttgggac aataattctt
    12481 ataatttgcg agaaccatcc tgtataagtg ataattcaac atttgagtga gtagccataa
    12541 agattgaaat ttgtttcatg aattgtatag caaacagtga tgttaattca acacgaatca
    12601 tctctttttt tcttgattta attgctgaat atccgcaaca atttgattaa agtcatccac
    12661 aaggtctttg cctttgtgat aaagaatatc tccagcttcg gttagtagta gctgtcaatc
    12721 actttgtgta aaaagcgtcg tgttcaaact aggactctag ccttttaatt gattgagaaa
    12781 gagtatgttg cgttacaaac aaacttttag cagcgtggga atgatttttt gtttcagcaa
    12841 ctgcaataaa ataggttaat tatctaatat ccatagtaga tccttcatga ttggtcaggg
    12901 aattgcgtct ctacttggtt tacaacctat tttgatgtct ctccttattg ccatgatttt
    12961 ctgcttcctt attgtttctc caattacaac ggtaggaatt gctcttgcga ttaacttatc
    13021 tggtattggt tcaggtgctg caaacttagg tatttgtgcc gcaagctttg gactttgctt
    13081 agcaggttgg gctgttaatt caaaaggaac ttcacttgct cacgtcttgg gatcaccgaa
    13141 aatttcaatg gccaacgttt tatcaaaacc aaaaatcatg ttgccaatgt tatgttctgc
    13201 agctgtactt ggtgttattg gtgctatctt taatattcaa ggaacacctg ctagtgcagg
    13261 ctttgggatt agttgtttga tcggacctat caatgccctt aatttagcta aaggcggatg
    13321 gtctctagta aatatcctac ttatcattat catttttgta agggcaccaa ttgttctcaa
    13381 tatgatcttt aactaccttt ttatcaaggt gcttaaagtg attgatccaa tggattacaa
    13441 acttgatatc taagaaagga acttttgatg aaattaaaat tatataatgt tagaggcgaa
    13501 gaagcagtct tagcaaaaaa atgggctgat gacaatggga ttgagatttc cttgacagag
    13561 tcttccttaa ctcctgaaac ggttaaagaa gctgaaggct ttgacgggat tgccaatgcc
    13621 caaattggtc ctttagatga tgcgatttat cctctcttaa aggaaatggg gattaaacaa
    13681 atcgctcagc gcagtgctgg tgtcgatatg tataaccttg atttggccac cgaaaatgac
    13741 attattatca caaatgttcc tagctattct ccagaatcca ttgcagaatt tacggttact
    13801 attgccctta atttaattcg tcatgtggag ttgattcgtg aaaatgttaa aaaacaaaat
    13861 ttcacttgga gactccctat ccgcggccgt gttttaggtg atatgacagt tgcgattatc
    13921 ggaactggcc gtattggtct agctactgct aaaatcttta aaggttttgg ctgcaaggtc
    13981 gttggatatg atatttacca aagcgatgct gccaaagctg tcttggacta taaggaatct
    14041 gtagaagaag cgattaaaga tgctgatctt gtttccttac acatgccacc aactgcagag
    14101 aacacacacc ttttcaatgc tgatttattt aaatcattca aaaaaggggc tattttgatg
    14161 aatatggcgc gtgctgctct cattgagacg caagatttac tggatgcttt ggatgcaggc
    14221 ttactgagcg gagctggtat tgacacttac gaatttgaag gaccttatat acctaagaat
    14281 tttgaaggtc aagaaattac agattcacta tttaaagctt tgattaacca tcctaaggtt
    14341 atttatacgc ctcatgcagc ttattgtact gatgaagccg ttaaaaacct agttgaaggt
    14401 gcccttaatg ctacagtaga gattatcaaa actgggacaa cgacaactcg tgttaactaa
    14461 caactgattt gacgtccatt ataaaggaat aattttaaaa attcctttat aatggacttt
    14521 tttgcattag tccgttataa tagactgtaa gaaaggggac tcttatgaca tatatagcgc
    14581 ttattggaga tattatccag tccaaacaat tgacggatcg ttccaaagtt caaaaaactt
    14641 tagcagctta tttagacgac ctcaacaaaa cctttgctcc ttatattatt tctaaattat
    14701 ccctaacgtt gggagatgaa tttcaaggac tttttcaggt ggatactcct attttccatc
    14761 tgattgattt gattaatcat cacatggata tccctattcg atttggagta ggagtaggtt
    14821 ctattctaac agacatcaat cctgatatta gtattggggc tgatggacct gcttattggc
    14881 atgctcgtga ggctattcgt tatattcatc aaaaaaatga ttatggtaat actacattag
    14941 ctcttcggac tggtcatcac aaccaggatg atgtattaaa cagtttacta gcagctggag
    15001 atgctattaa agccaactgg cgagctagtc aatgggaaat ttttgacacg cttttagatt
    15061 tgggcattta tgaggaatac tttgatcaac aacgactagg aaagcaatta tctcttagct
    15121 ctagcgcttt gtcaaaacgt ctaaaaagta gtcatgttaa aatttatctg agaacacggc
    15181 agagtgcgct aaactgtctc aaacaaatca aggaggaaac tgatgattaa tggtgtctct
    15241 cactacctag ctcaaacccc tacacttacc ctgtttctca tttgtcatgt gttatcagac
    15301 taccagttac aaagtcagca agtagctgat ttaaaagaaa aacatttgac ttatttaggt
    15361 taccacttga ttggagttag cattccccta atttgtttaa ccctcattat cccacaagca
    15421 tggttgatga gcctattggt tatgataagt cacgcgctta ttgactggct aaagccaaag
    15481 atggctaact ctctaaaatg gaaaagagag tggatttttc tgctggatca atgcttacat
    15541 atcgctatta gttcatttgc tgggctaagg ttagcagggg tgaccttgcc taattggctt
    15601 ccgatatcta ttttgatgac cgttttattt atcctactca ttaccaaacc aactaatatt
    15661 gtctttaaac tctttttcag caaataccag cctgaccaag gagaaaaaat ggacacgatc
    15721 ataggagcgg gggctaccat aggaattcta gagagaattg ttattggggt gtgtatgatc
    15781 atggggcaat ttgcttcaat aggtctggtc tttaccgcta aatctattgc tcgctataat
    15841 aaaatttcgg aaagtccagc ttttgcagaa tactacctaa ttggttcttt atttagtatt
    15901 ctcagtgttt ttatcgcagc atggatttgt ttcttctagt tgaaaagggt tcccgtagaa
    15961 agaggctaac gcttagtctc tttctttttc tttcttctta tttctgttat aataagtcag
    16021 gtaactacat tagaaagatt tgtgggtctg tcatctaaga gatgtcattc ccgaagaggt
    16081 attagtgact tgtctcaatc aactgcaact tatattaatg ttattggagc tggactagct
    16141 ggttctgaag ctgcctatca gattgctaag cgcggtatcc ccgttaaatt gtatgaaatg
    16201 cgtggtgtca aagcaacacc gcaacataaa accactaatt ttgccgaatt ggtctgttcc
    16261 aactcatttc gtggtgatag cttaaccaat gcagtcggtc ttctcaaaga agaaatgcgt
    16321 cgcttggatt ccattattat gcgtaatggt gaagctaatc gtgtacctgc tggaggagca
    16381 atggctgttg accgtgaggg gtatgcaaag agtgtcactg cagagttgga aaatcatcct
    16441 ctcattgagg tcattcgtga tgaaatcaca gaaattccta acgatgccat tacggttatc
    16501 gcgacgggac cgctgacttc ggatgccctg gcagaaaaaa ttcacgcggt aaatggtggc
    16561 gatggattct atttctacga cgcagcagcg cctatcattg ataaatctac tattgatatg
    16621 agcaaggttt acctcaaatc tcgctacgat aaaggcgaag ctgcttacct caactgccct
    16681 atgaccaagg aagaattcat ggctttccat gaagctctga caaccgcaga agaagccccg
    16741 ctgaatgctt ttgaaaaaga aaagtatttt gaaggctgta tgccgatcga agttatggcc
    16801 aaacgaggca tcaaaaccat gctctatggc cccatgaagc cagtcggctt ggaatatcca
    16861 gatgactata caggtcctcg cgatggagaa tttaaaacgc catatgccgt cgtgcaattg
    16921 cgtcaagata atgcagctgg aagcctttat aatatcgttg gtttccaaac ccatctcaaa
    16981 tggggtgagc aaaaacgcgt tttccaaatg attccagggc ttgaaaatgc tgagtttgtc
    17041 cgctacggcg tcatgcatcg caattcctat atggattcac caaatctttt aacggaaacc
    17101 ttccaatctc ggagcaatcc aaaccttttc tttgcaggtc agatgactgg agttgaaggt
    17161 tatgtcgaat cagctgcttc aggtttagta gcaggaatca atgctgctcg tttgttcaaa
    17221 agagaagaag cacttatttt tcctcagaca acagctattg ggagtttgcc tcattatgtg
    17281 actcatgccg acagtaagca tttccaacca atgaacgtca actttggcat catcaaagag
    17341 ttagaaggcc cacgcattcg tgacaaaaaa gaacgttatg aagctattgc tagtcgtgct
    17401 ttggcagatt tagacacctg cttagcgtcg ctttaacact aaaaaagagt tccttttcag
    17461 ttgagttgct gaagaggact tttttacttg ctgatttgag cgctagctat gcaaaagaat
    17521 gcacaaaaaa tacatgaata gactatggtc actagaagca atattatata atgaatagta
    17581 ctcattagtt gattcagttt ggaggtttta gcatgcagca gcaagtcgca ataacagaaa
    17641 cagttttacg ggacggtcat caaagtttga tggcaacgcg tttatctatt gaggatatgc
    17701 ttcctgtcct taccatctta gacaagattg gttactattc cctagagtgt tggggaggag
    17761 caacctttga tgcctgtatt cgttttttga acgaagaccc ttgggaaagg ctgcgcacgt
    17821 taaaaaaagg cttacctaat acccgtttac aaatgttatt aagaggccaa aaccttttag
    17881 gctaccgtca ttatgcagat gacatcgttg acaaattcat tagtttatca gctcaaaatg
    17941 ggattgatgt tttccgcatt tttgatgccc taaatgaccc acgaaatatc cagcaagcct
    18001 taagagctgt gaaaaagacg ggtaaagagg ctcaactgtg tattgcctat acaactagcc
    18061 cagtgcacac gcttaactat tacctttctt tagtgaaaga attggttgag atgggagctg
    18121 attctatctg catcaaagat atggctggta ttctaactcc caaagcggct aaagagttag
    18181 tatctggtat caaagccatg actaacttac ctcttattgt gcatacccat gcaactagtg
    18241 gcatttctca gatgacctat ctagcaacag tagaagctgg tgctgataga attgatactg
    18301 ctttgtcacc ttttagcgaa ggtacttcac aacctgctac agaatccatg tatttagcct
    18361 taaaagaagc aggttatgat atcacattag atgaaacgct actggaacag gctgctaatc
    18421 accttcgaca agcccgtcaa aagtacttag cagatggcat tctggatccc agtcttctct
    18481 ttccagaccc aaggacacta caataccaag ttcctggagg catgttatct aatatgctat
    18541 ctcagctgaa acaagccaat gccgaatcaa aattagaaga agttttagca gaagttcctc
    18601 gggtaagaaa agacttgggt tatcctccct tagtaacacc gcttagccaa atggtcggga
    18661 ctcaagctgc tatgaatgtg attttaggaa aaccttacca gatggtgtct aaggaaatta
    18721 aacaatactt ggcaggcgac tatggcaaaa caccagcacc agtcaacgaa gacttaaaac
    18781 gaagtcaaat tggctcagct cctgtcacca caaatcgtcc tgcagatcaa ctaagtcctg
    18841 aattcgaagt gttaaaagca gaagtagcag atttagccca aacggacgaa gatgtgctga
    18901 cttatgccct cttcccaagc gtagcaaaac cgtttttaac aaccaaatac caaactgatg
    18961 acgtcattaa agtgactgcc tttatcaaag cataataggc tatcttaatc agatagaaac
    19021 aaaaatatgg agatcacatg acctattcct ttattgatat cttacaagtt accttagtat
    19081 ccttgttctt agtgttaacc tgtttaacag ggattatggg attaatgatg ctaagtggta
    19141 aattattgtc acaagaaaaa aaaactctct ctcaacaagc ttccagcatt cctcaagagc
    19201 aagaagctga caagttgagt ggagaagctc tcgaaactct tttagccaaa gacgaattgg
    19261 ctagaattgc tgttatgact agtcttgctt atgctagcca agaagagtca ggaaaacggt
    19321 ttgaagttat tgccgtggaa aggaaatcct aatgaaaaga tatgaagtga ctgtcaatgg
    19381 acaggtttat gaagtgagtt tacgtgaact agctgatgga gaaactgttg aagttagccg
    19441 gccagcagca cctgctactg agaaagaaat gaatgccaac gctgctggcg gtggcattca
    19501 ggtaaaggct ccaatgtctg gaacagtctt gtctatcttt gctacagaag gaaaagctgt
    19561 taaaaaagga gaagctgttc tggtcttaga ggccatgaaa atggagaatg aaattctagc
    19621 acctgcagat ggtctggttt caaaaattca tgttgtggct aaccaaacgg tcgagtctga
    19681 acaagttttg atttcattct aggaggaaac catgctagac gtactcaatc aaatggttca
    19741 atcgtcagga ttggctcatc taactgttaa caatcttatc atgatttgct tggcctgttt
    19801 ctttttatac cttggtatca aaaaggaata tgagccttac cttatggtac caatcgcctt
    19861 tgggatttta ctcgttaatt tgcctatggc gggattgatg gaccaccctg ccaatggtaa
    19921 tcctggtggc cttctttatt acctatataa gggaactagc ctagggattt acccaccttt
    19981 aatttttctt tgtttggggg catcaactga ctttggtccc ttgattgcca atcctaaaac
    20041 cattttacta ggaggcgcag cacaagttgg gattttctta gcctttttcc ttgctattat
    20101 gttaggcatg acacctcaag aagcggcttc tgtcgggatt attggtggtg ccgatggacc
    20161 aacagctatt tatgtgacga caaagttggc gcctgattta ctctctacta tcgccctagc
    20221 agcttattct tacatggctc tggtacctat tattcaacct cccatcatta aactcttgac
    20281 taccaaggcg gaacgccaag tgaaaatgac tcaagcaaga actgtttcac aaaaagaaaa
    20341 aatcattttc ccgattatgg taacaatctt tgtcagcctt ttggttccaa gtgctacaac
    20401 cttggttggc tgtttgatgc tgggaaatct ggtcagagaa attaaaattg ttcctaaaat
    20461 tgtagagaat ctccaacaag tagttatgtt ttgcattacg atcattttag gattaaccgt
    20521 tggtgctaag gccaatggag atctcttttt atcagccaca accttgaaaa ttattgccct
    20581 tgggctaatc gcctttgctg ctgggacagc agggggtgtc ttgatgggga aaatcatgta
    20641 ctatttatct ggtaacaaag tgaaccctat gataggagca gcaggtgttt cagctgttcc
    20701 gatggcagca cgagtggtcc aaaagatcgg acaagaagaa gatccaagta atttcttact
    20761 catgcacgcc atggggccca atgtagctgg cgttattggc tcagccattg cctcaggtgc
    20821 cttgctggcc ttctttggct aattgtgaaa aaggattagt aaattaatct taataaatca
    20881 ttatcaggag ttggaagcaa tctagctcct ttttagtaga aagctcgagt gataaactat
    20941 tccaaaataa ttataaaaaa agactgtcct gattgtacgg actatatcaa ttgactttta
    21001 tagtctagct gaaatagcag tgcaaaacta agacactcgt tttaaagtag tttttctaaa
    21061 aaagcaaaat aaaaggtcag agccaataaa tctgccgcgc ccccagggct taaatgctga
    21121 ttaatgaggc attgattgta ggaggacaaa gccaatctta ggtcagttgt tgataaatct
    21181 tgttgcagga gtagtcgcat atctgcctta acgcctttcc atgcttcaat ccctccacga
    21241 tgaatcagat ttccatcttc aacaatagac atcaaataaa caagaagacg aagctgactg
    21301 gtttcggggt cattttgact tatcatctga cgaaagtagg gcaaggcatg gtctgttaag
    21361 gtcgtgaatc cctcgcttgc ctcaccccga ggtcctttga tgccataagt tacaaagagt
    21421 tgctccccat aagtgaactc ttttttagtg ttcaaatgac caaggtctgt ttgaatcaaa
    21481 tgtgccgtca taggttttac taaacgacag atagctagag tatcttcctt gctaaaacgc
    21541 cctaaatcag tcattaagtg aggtgttctt gctagatagg ccccagttgc accaagaagt
    21601 aaagccatgg aaaaattcaa gcctttatga gtgttaattc cctgagtagc acaaaacatg
    21661 gtttcctcgg ccttttgacc tagttgtcta agacggttaa acagaagaag tggctcttct
    21721 tttgcataag caaaacctgt ttcgatataa gcctgaaaaa aaggagagag tgctatcata
    21781 ctgtcgataa aggtcataaa ggacatgtca tcatgggcac cgttatcaaa tcgatcaact
    21841 aaaccaggtt ttggagatag tgagacttca taaagcaaag cttttaaggc cagttgacta
    21901 atacttgtta gaactgcctt agtcattttg ctcaggcctc atttctttta agataaattc
    21961 aagtgagcta ttcaagtgtt catgtgtaat caacgtaatt tgctcatgat ctttgttctt
    22021 catacctcgg taaatcatcc agtgttcaga tagagctcgt ttacggcgtt caactgaaga
    22081 aatcgaaatt tttctaaagt agaccaaata agcttgcaat tctgtcacaa tttcttttaa
    22141 gcggaccatt tggctatagc tgtaaatcaa attgttaaag gcattaaaat tatccaaaat
    22201 acgattggtg tcatcctctg cgataaaggt ttcacagtct tccaacaagt tatgcatgac
    22261 tttaaaatct tcttctgtca ttaaatgcat cgcttgcacc gttgcgagag tctctagagc
    22321 ttttcgaatt tcaaaaattt cacaggcatc cttgatacta actcctttga caataatgcc
    22381 ttttttagga atgtgctcta caaggtgttc ttcagacaat aatcccaaag cgtagcgaat
    22441 aggtgtcctg ctaatattaa gcgcaatgga aaactctttt tcattaatgc ggcttccaac
    22501 aggaatttgt cgcaaaataa tggtcttttt aagagcgtta taaaaggcta ttttcaaagg
    22561 gatatttctt gataggtcaa gattttgttt aacggcttcg ataataggat tcatgtcatc
    22621 tccttaatgc tagtgtcctc actttattat acttaaattt gtgaaacatt ccaataggac
    22681 tagatgagtt ctgaaaaatt aaagccatgc tcacaaaagg acatgacttt aatcatctca
    22741 taaggaataa ggtagtagtg ttatcgttgg tttattgtgg aatgtaaagt ggcatttgtc
    22801 ccatggcaat aatggttacc acaaagataa caaagatgat aagggcatat ttagcagcct
    22861 ctttttgcca ttcccccatg tcaagacctg tcaagcgaag aagaagataa atgaaggcaa
    22921 ctaatggact aagtaagtgg aaggcttgtc ccatgaggga agcaagtgcc atagccatgt
    22981 tactgaaacc atattcagca ccagcttctg caagaacagg caagatacca tagtaaaaac
    23041 catcattgga gataaagaag gtaccaggtg cagaaactaa ggcaataacg agcccccaga
    23101 aacctgccag ttgttttgga ataatggttg caaaactttg tgcaagagcg ctagccatac
    23161 cagaaccttg gaaaagaccc ataaagatac cagcagcaaa gacgagaata accacttgaa
    23221 ccgcatcacc agcattatca ccaatgcgtt tcgattgatc tttaagcact gggtaattga
    23281 ccatcaaggc gatacaagtt cccaccgcaa aaagaagaag cggtgccata gcaatagatt
    23341 tgttgaaaga gccagcaact aaccaagtga ttaatccaat ggttaagata gcattgaaaa
    23401 caaagttttt aggacgacga ataaaaaggg tatctgggtc agtaatgtct gtgagttgac
    23461 gcatgtcttc ttcagacaag tcaataacac caagtcttgc acgttcttta cgccccatgc
    23521 ttggagcaac ccaacaaatc acataaagaa gagataaaat catacccggt gcaagatagc
    23581 caagaatttc aggaccgaca ccaagaacag acatcgcacg agcagtagga ccaccccatg
    23641 gcagtaagtt cataatagta ttttgaagaa taatcaagac acctaggttc atgattttca
    23701 tgtccaattt tttatagata ggtaagaaag cagagcaaca aattaaagta gtggttgttc
    23761 catcaccatt aagagatact gcggcagcaa cgacagctgt tgcgataagc accttcattg
    23821 gatcaccttt agcaaagcga atcatctttt cagtaatcgg atcaaacaat cctgcatcta
    23881 acatgacaga gaagaacaaa atggcaaata gcaacatgat acctgtttta gcagtattgt
    23941 tgataccata cataaccatt ggtccgatag ctgttaggtc tttagcaatt ccaccgtcac
    24001 caacaaaggc aacaaatttg gcatctgcat tgaagtcagc tgaaccagtc agtataacag
    24061 caattgtcat gattaatgga atcatgacca aagcagtaaa aggggtcatt tttttcttca
    24121 ttaccacgta cataaagaca ataatcatgg cataagccag cattgttaat aacatcattg
    24181 ttatctcctt tttcaagtta tgatttcagt atagatgaaa gcgcttataa aataaatact
    24241 tctttgtgca ga
//
LOCUS       DAUCXI010000028        22874 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.028, whole genome shotgun sequence.
ACCESSION   DAUCXI010000028 DAUCXI010000000
VERSION     DAUCXI010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22874
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.028"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            51..122
                     /locus_tag="VGY43_001192"
     tRNA            51..122
                     /locus_tag="VGY43_001192"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:83..85,aa:Gln,seq:ttg)
     gene            249..1454
                     /gene="rpsA"
                     /locus_tag="VGY43_001193"
     CDS             249..1454
                     /gene="rpsA"
                     /locus_tag="VGY43_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEQ4302377.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
     gene            1567..1638
                     /locus_tag="VGY43_001194"
     tRNA            1567..1638
                     /locus_tag="VGY43_001194"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1600..1602,aa:Arg,seq:ccg)
     gene            complement(2001..2303)
                     /locus_tag="VGY43_001195"
     CDS             complement(2001..2303)
                     /locus_tag="VGY43_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302378.1"
                     /translation="MTYELCLEYGTYPLSRVDAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPKKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            2505..3491
                     /locus_tag="VGY43_001196"
     CDS             2505..3491
                     /locus_tag="VGY43_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEQ4302379.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA"
     gene            3802..4188
                     /locus_tag="VGY43_001197"
     CDS             3802..4188
                     /locus_tag="VGY43_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HEQ4302380.1"
                     /translation="MLFIAKQTLKSQLIPQDNLLAESRFNEIMDFLTGDFPLVFRPMY
                     NPHRYTISQDNQALEKVKQASYKRMDIAMTHLDGLIGDSGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLAAFMAKMLEM"
     gene            4247..5155
                     /locus_tag="VGY43_001198"
     CDS             4247..5155
                     /locus_tag="VGY43_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEQ4302381.1"
                     /translation="MKHLKNPPLVMSGLALGTLSFGNLLATYVSIFSYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFLTWWLF
                     FLGNLVLIAYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     ISSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
     gene            complement(5273..5449)
                     /locus_tag="VGY43_001199"
     CDS             complement(5273..5449)
                     /locus_tag="VGY43_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEQ4302382.1"
                     /translation="MVKKYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            5583..6482
                     /gene="miaA"
                     /locus_tag="VGY43_001200"
     CDS             5583..6482
                     /gene="miaA"
                     /locus_tag="VGY43_001200"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEQ4302383.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLIDIREVTESYSAYDFVQDAQKAISDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVDRMLENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            6555..7793
                     /gene="hflX"
                     /locus_tag="VGY43_001201"
     CDS             6555..7793
                     /gene="hflX"
                     /locus_tag="VGY43_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEQ4302384.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RISARSKDSKILLRRLIIDQIRDQFVPFRIKVHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            7786..8421
                     /locus_tag="VGY43_001202"
     CDS             7786..8421
                     /locus_tag="VGY43_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEQ4302385.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKGQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFAQREFMIYITQ"
     gene            8436..9365
                     /locus_tag="VGY43_001203"
     CDS             8436..9365
                     /locus_tag="VGY43_001203"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEQ4302386.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFEVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            9365..10129
                     /locus_tag="VGY43_001204"
     CDS             9365..10129
                     /locus_tag="VGY43_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEQ4302387.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAKEIADM
                     FQVNTLASIHFACLIGQKMADQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            10126..12336
                     /gene="recJ"
                     /locus_tag="VGY43_001205"
     CDS             10126..12336
                     /gene="recJ"
                     /locus_tag="VGY43_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEQ4302388.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYDRGIRTE
                     EALDEFLTADLSQLHDPYLLHDMTKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DESLSLDDLSLDILKSLDKLAPYGMDHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKTWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            12486..13004
                     /locus_tag="VGY43_001206"
     CDS             12486..13004
                     /locus_tag="VGY43_001206"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEQ4302389.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            13085..13768
                     /locus_tag="VGY43_001207"
     CDS             13085..13768
                     /locus_tag="VGY43_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEQ4302390.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTSQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEERRRVREGEDLSQVTISEDFL
                     SAMNLWSDS"
     gene            13765..14421
                     /gene="nth"
                     /locus_tag="VGY43_001208"
     CDS             13765..14421
                     /gene="nth"
                     /locus_tag="VGY43_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEQ4302391.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQNTYGKSKA
                     "
     gene            14493..15179
                     /locus_tag="VGY43_001209"
     CDS             14493..15179
                     /locus_tag="VGY43_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEQ4302392.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPIFLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIA
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            15169..15957
                     /locus_tag="VGY43_001210"
     CDS             15169..15957
                     /locus_tag="VGY43_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEQ4302393.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            15997..17103
                     /locus_tag="VGY43_001211"
     CDS             15997..17103
                     /locus_tag="VGY43_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEQ4302394.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAIKNRKELGNDFKGLIGFDNCLYASGAARVEGAALCETLL
                     KASGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLRPLGYQVDVRPQKGQ
                     LLDYDVHHIISDTYPVVMPEGEIDLIPFNQGKISVGASHENDKGYDLEPDWQVLEKIE
                     MQALTYLPLLKEATQKSCRVGIRAYTSDYSPFYGQVPGLKNLYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLRSTGKA"
     gene            17161..18030
                     /gene="rfbA"
                     /locus_tag="VGY43_001212"
     CDS             17161..18030
                     /gene="rfbA"
                     /locus_tag="VGY43_001212"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEQ4302395.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHKLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            18030..18623
                     /locus_tag="VGY43_001213"
     CDS             18030..18623
                     /locus_tag="VGY43_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HEQ4302396.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAAEVSEADKNHPLLSDVKPLKPKDL"
     gene            18867..19907
                     /gene="rfbB"
                     /locus_tag="VGY43_001214"
     CDS             18867..19907
                     /gene="rfbB"
                     /locus_tag="VGY43_001214"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEQ4302397.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(19990..21129)
                     /locus_tag="VGY43_001215"
     CDS             complement(19990..21129)
                     /locus_tag="VGY43_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ4302398.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMEKDTPRIRKEAQ
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSVRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMAYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
     gene            complement(21249..22106)
                     /locus_tag="VGY43_001216"
     CDS             complement(21249..22106)
                     /locus_tag="VGY43_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEQ4302399.1"
                     /translation="MKNISPLRYPGGKSQVYDYVRELVIANDAITYIEPYMGGMGIAL
                     KLLLNNNVHKIMVNDYDKAIYAFWYSVLNYTEQLIEKINTTPITIDEWKLQREVQKNK
                     NNCDDLLTLGFSTLFLNRTNRSGIIKAGVIGGLKQDGNYKLDCRFNKEKTIKKIKLIA
                     SYKKQIKLYNMDAEKFIRLNITKTKNSFTFFDPPYYTKGPGLYTNFYNHENHHSLSST
                     IKHYMSNKNWILTYDLSEEIFQMYKEFKYEKYYLNYSVTKPSKGIEYIFYSNGLAVPE
                     NTINIKKAN"
     gene            complement(22145..>22874)
                     /locus_tag="VGY43_001217"
     CDS             complement(22145..>22874)
                     /locus_tag="VGY43_001217"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEQ4302400.1"
                     /translation="VDLLKHLNKYSINALLQNKLVNNVYVKQPIPVLLEDNEAKDFFQ
                     NLLQAYFERYQLSLESFFHIIDAKISSSAIKALAQDRYTNQSSLRIISITDGDEQLGQ
                     QYLTHNLFSLPGNYSPEELIFKYLKEVLLDDYNFWQKQDIIAAGYTKKLVQESFITQL
                     DELEAKLNQPGSHHGVKREENKKIYNCDTNFWNYVMKYWIDDTNNQDEVLKFFDNLKI
                     AFHKTAPFYNINPTSSWPFITGQL"
BASE COUNT         6897 a         3986 c         4872 g         7119 t
ORIGIN      
        1 tttcggaaac taatctaatt agaaaattag ttttctgtaa aaaatatttt tggggtatag
       61 ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc cagctacccc
      121 agtcagaggt atcaggtgct ccctgagacc gtcaaagata agagttgttg tcgttgcggg
      181 ttaccttgag aaaatatatt gttatcaaaa gctagcattg gctagctttt gttggaggat
      241 tttttagaat gaatgaattt gaagatttgc taaacagtgt tagcgaagtg aaccctggtg
      301 atgttgtcac tgcggaagtt ttaactgttg ataacggtca agcaaacgtt gttatcgaag
      361 gaacaggtgt tgaaggtgtc ttgacacttc gtgaattgac taacgaccgc gatgctgata
      421 ttaacgactt tgttaaagct ggcgacacag ttgaagtact tgttcttcgt caagtagtag
      481 gtaaagatac tgatacagtt actttcctag tatctaaaaa acgtttggaa gctcgtaaag
      541 cctgggacaa acttgttggt cgtgaaggcg aagttgttac tgttaaaggt acccgtgctg
      601 ttaaaggtgg tctttcagtt gaatttgaag gacttcgtgg atttatccct gcttcaatga
      661 ttgacactcg ttttgttcgc aacactgaaa aatttgttgg acaagagttt gatgctaaaa
      721 tcaaagaagt tgatgcagca gaaaaccgtt tcatcctatc acgtcgtgaa gttatcgaag
      781 aggccgctaa agaagctcgt gctgaagtgt tctctaagat ttcagaaggt gcagtcgtta
      841 caggtactgt agcgcgttta acaagttttg gtgctttcat tgaccttggt ggtgttgacg
      901 gacttgttca cgtgactgaa ttgtctcacg aacgtaacgt gtcacctaaa tcagttgttt
      961 cagttggtga agaagttgaa gttaaagttc tttcaattga cgaagaagct ggtcgtgtgt
     1021 cactttcact taaagcaaca acacctggac catgggacgg cgttgaacaa aaacttgctc
     1081 aaggtgatgt tgttgaaggt aaagtaaaac gcttgactga cttcggtgct tttgttgaag
     1141 tattaccagg tattgatgga cttgttcata tttcacaaat ttcacacaaa cgtgttgaaa
     1201 atccaaaaga tgtactttct gtaggacaag aagtaacagt taaagttctt gaagtgaatg
     1261 cagctgatga gcgcgtatca ttatcaatca aagctcttga agaacgccca gcgcaagctg
     1321 aaggagacaa caaagaagaa aaacgtcaat cacgcccacg tcgtccaaaa cgtgaatcaa
     1381 gacgtgacta cgaactccca gaaacacaaa ctggattctc aatggctgat cttttcggtg
     1441 atattgaatt gtaataaatc taaaaagttg aggttttcct caacttttta ttgtcttctg
     1501 gttagaaaag ttatttcata ttatttcatt ttatgatata ctataagggt attgacaaag
     1561 ttgtgaccac ctttagtgta atggatatca cgtaagattc cggttcttga gatgggggtt
     1621 cgattccctc aaggtggata gaaatcatat aaaaaagccc tatttgatag gctttttttg
     1681 tttcttttcc aaaatttgtc caaaattatc tagaagagtt gacgaacctt ttcaaaatca
     1741 ttatttttct gaccttgaaa acgatgagta taggtcttaa atgtctctgt aatgccacag
     1801 cctgaatttt atttgactca gattcataag attgtaagta atcaaggtta attattgatg
     1861 agatggtgaa accattttta gcaagtgcta ttaaagcatt tagtgatttt tcgaaacgtt
     1921 ttaaaattta agaagagttt tacctaaaaa actagctgtg tcatctatct aagcacagtt
     1981 agttttttag tattagattt ttaaagaaga aacgtctcaa tcttaattgg ataatcctta
     2041 tatttggatt ttaatatagt agctacttct tgatatagta tccgaatctg cgctcttttt
     2101 ttaggcatgt taaaaccaac ataatggaat tgtgattcaa tagttacaaa taaatcatgg
     2161 aacaggtgat tcatagtttc taatttatgg caaagcagtc gatcttcttg aatgaatgtt
     2221 gggggatttt gatcttctcc ccagtaagca tcaacacgtg acaacggata agtcccatat
     2281 tctaaacaaa gttcataagt cattttggcc tccttgtttt atcttagcat tttctaaata
     2341 aagcttctaa tgatttgctt aaaggagtaa tgggttgcca tctcatctca tcaaaaataa
     2401 attgagatct attttgtgaa aaaaaaagac aaacaaatgg cttgcctaga cttgtttttc
     2461 ctagatataa taggaagtaa ctgaataaca atgaaggaga aaaaatgtca gaaaaaatca
     2521 gagttttact ctattataaa tatgtttcaa ttgaaaatgc gcaagagtac gctgcgaaac
     2581 atctagaatt ttgtaaatct attgggctta aaggtcgtat tttgattgcg gatgagggga
     2641 ttaatggaac tgtttctgga gattatgaaa caactcagaa gtatatggat tgggtccaca
     2701 gcgatgagcg ttttgctgat ctttggttca agattgacga ggaaaatcaa caagctttcc
     2761 gtaaaatgtt tgttcgttat aagaaagaga tcgtgcacct tgggttagaa gacaataact
     2821 ttgatagtga tattaatcct ttggaaacaa caggtgagta tttaaatcct aaacaattta
     2881 aagaagcctt gcttgatgaa gatactgttg ttttagatac gcgtaatgat tatgagtatg
     2941 acttaggtca cttccgtgga gcaattcgtc ctgatattcg caatttccgt gagttaccac
     3001 aatgggtacg tgacaacaaa gataagttta tggaaaaacg tgttgttgtg tactgtacgg
     3061 gtggtgttcg ctgtgagaaa ttctcgggtt ggatggttcg agaaggcttt aaagatgttg
     3121 gacaattaca cggtggtatt gcaacatatg gaaaagatcc ggaagttcaa ggtgaacttt
     3181 gggatggtgc gatgtatgtt tttgatgatc gtatctcggt gccaattaat catgttaatc
     3241 caactgtcat tagtaaagat tattttgatg gaacaccttg tgaacgttat gtcaattgtg
     3301 caaatccgtt ttgtaacaaa caaatttttg cttcagaaga aaacgaaaca aagtatgttc
     3361 gaggatgctc gcctgaatgt cgtgcacatg aacgtaatcg ctatgtgcaa gaaaatggtt
     3421 tatcacgtca agaatgggca gaacgtttag aagctattgg agaatccttg ccagaatttg
     3481 taggtgccta atatctcaaa acaaatcagg aaactggttt gttttttgtg atacagatga
     3541 tgagaccaaa ttgcaaagac tttgcaacaa gatactagtg aacgtggaca ccaagctcat
     3601 tttgtcatgc agagccatca acagcgaaga cgtcaacacc aactctgtct agaacctttt
     3661 caaaagaatt gtgagtttct gtattacgag atagagaagg taaaactgga ttctgaagac
     3721 tgccttacca tcaatccttt gggaatggtt taagctttac agcttgatga tggtcaaatc
     3781 gtcacacagg caggtattat cttgctcttt atagcgaaac aaaccctgaa atctcagctc
     3841 attccccaag ataatctttt ggcagaaagt cgattcaacg aaatcatgga tttcttaaca
     3901 ggtgattttc cccttgtttt taggccaatg tacaaccctc atcgctacac tatttctcaa
     3961 gacaatcaag cgcttgaaaa agtcaaacaa gcttcttaca agcggatgga tattgctatg
     4021 acgcatttag atggtcttat tggggatagt gggcatgttt atcgagatca acaaaccatt
     4081 gcagatgctt atgcttacgc catggcgcta tggtctcaaa aaacaccaaa atcttacgag
     4141 aattatccgc atctggcagc ctttatggca aaaatgctcg aaatgtgata aaataaacaa
     4201 gattatgtca ctaaaaatag ctgttaatag gcagaaaagg acacttatga aacaccttaa
     4261 aaacccacca ttggtcatgt caggattggc attaggaacg ttgtcatttg gtaatttgtt
     4321 ggctacttat gtttcgattt ttagttattt gggaattctg gcagctcttt ttatctatgg
     4381 tatcttgctt gttggcatgg ttaggaacct taacgatacc aaaatgcagt tacgacaacc
     4441 tctaattgcc tctgtttttc caactttttt tatgacaggg atgttgttgt cttcactctt
     4501 tctcaaagtg acaggagggt gttggttagg ctttctcact tggtggctat tctttttggg
     4561 aaatcttgtc ctgattgctt attaccagta tcgttttgtc ttttcttttt catgggataa
     4621 cgtttttcct tcctggtccg tgctttttgt tggaattgca atggcggcat taacagcacc
     4681 tgctagtagg cagtttttat taggacaggt gattttttgg gtttgtcttc tcttaactgc
     4741 tgtgatttta ccttttatgg ccaaaaagac ttatgggatt ggtttaggtc aagcagtaat
     4801 gcccaatatt tcaacgtttt gtgcccctct gtccttactt tcagcgtctt atttagcaac
     4861 ctttcctaga ccacaagtag gaatggttat ctttcttctc atcagctcac aactgttata
     4921 tgcttttgtg gttgtacagc ttcctcgctt actcaatcgt ccctttaacc caggtttttc
     4981 agcttttacc tttccgtttg tgattagtgc cacttcctta aaaatgacct tatctttttt
     5041 aggttggcaa ggtttaggtt ggcaggttct tttgctagga gaggtattgt tggcgacagc
     5101 tttagtcacg tatgtttatg gggcttacct gagatttcta tttcaaaata agtaaagcag
     5161 ctaacatctt ggctcatcaa gagacagtta ctactaacta gttatcgaga ttactaaaaa
     5221 agaggccggc actttaatgt gctagtctct tttaaattga tccattgtca cgttagcgag
     5281 ctacacgacg acgcgcagct tttttgcggt tttcttcaat gaaagcagct ttttcttctt
     5341 cagggtcaat gattgttttt tttacagcaa agacagcacc agcaacagta gcagcagttg
     5401 ctaggacgcc agtagcaaga cctttaacaa attgatattt cttaaccatg attattctcc
     5461 atttctagtg aaggacctca gtggtcctta atcttatgtt ataatatatg gtagcgaaaa
     5521 ataagctaat tttcaagtaa aaggcgtttt tggacacgct tttctaatag aaagacaaga
     5581 aaatgacaaa aataaaaata gttgtgattg ttggtccgac agcggttgga aaaacagcac
     5641 ttgggattag tttagccaag gcttttaatg gagaaattat ttcaggagat agccagcaag
     5701 tttatcgaca gttggatatt ggaacagcca aggccactca agaagagcaa gaagcagcgg
     5761 ttcatcactt aattgatatt cgtgaggtga cggagtctta ttcggcctac gattttgttc
     5821 aagatgctca aaaagctatt tcagacattg ttagtcgtgg gaaattacca attattgtag
     5881 gtggaactgg tctttactta caaagtttac tcgaaggtta tcatctagga ggtcaagttg
     5941 atcaagaggc ggtaaaagcc tatcggaatg agttggagca attggacgat cacgacttat
     6001 atgaacgctt gcaagtcaat aacattacca ttgagcaggt gaatcgcagg cgggcgatcc
     6061 gagcccttga attggctcag tttgctgatg aattagagaa tgccgagacg gcttatgagc
     6121 cgcttattat cggcttgaat gatgaccgcc aagtcatcta tgaccgtatc aatcagcgcg
     6181 tggatcgtat gcttgaaaac ggcttattgg aagaagcaaa atggttatat gagcattacc
     6241 cgactgttca ggctagtcgt ggcataggtt ataaggaatt attcccctat tttgtaggtg
     6301 aaatgacttt ggcagaagct agtgatcagt taaaacaaaa cacgagacgt tttgccaagc
     6361 gacagctaac ttggttccgc aatcgaatgg ctgttagctt cactgccata acggctcctg
     6421 attacccaca ggtagtacat gatagggtca gggattttct tggtcagaaa gagaagtcat
     6481 gacgcaaaat tagcagaatc tgttgaagat atgttataat agaatttacg gaatttggag
     6541 gattggtaaa ggtgatgatt gagacaaagc gtcagcaaga aagagtgatt cttttaggag
     6601 ttgagcttca gacaacagaa cattttgata tgtccatgac agaattagct aatcttgcca
     6661 aaacagctgg cgtcaaagtt atggcaagtt tcagccaaaa acgagaacgt tacgacagca
     6721 aaacctttat cggctcaggg aaactggatg agattaaggc gattgtggaa gctgatgaga
     6781 ttgatgcagt tattgtgaac aatcggttga ctgctaggca aaatgctaat ctagaagctg
     6841 ttttagaggt aaaagtcatt gaccgtatgc agttaatctt agatattttt gccatgcgtg
     6901 ccagaagcca tgagggcaaa ttacaagtac accttgccca attgaaatat atgttacctc
     6961 gtttggttgg acagggcatc atgttaagtc gtcaagcagg tggtattggg agccgtggac
     7021 caggtgaaag ccaactagag ttaaatcgcc gttcgattcg tcatcagatt gctgatattg
     7081 aacgccaatt aactcaggta gagaaaaatc gtcaaacaat tagagatcgt cgtgtgggtt
     7141 cagatacctt taaaattggc ttgattggct acaccaatgc tggcaagtca accattatga
     7201 acttgttgac agatgacagc cactatgaag ccaatgaatt atttgctacc ttagatgcaa
     7261 ctacaaagca actctattta gaaaatcaat ttcaagcaac cttaacagac accgtaggct
     7321 ttattcaaga cttgccaacg gaattagtgg ctgcttttaa atcaacccta gaagaaagca
     7381 aatatgtgga tttgctgtta catgtgattg atgcgagtga tcccaatcat agtgagcaag
     7441 aaaaagtggt tttaaacctt ctaaaagagc tagacatgct taatattcca cgtttagcta
     7501 tttataacaa ggtggatata gcagaacaat tcacagctac tgcttttcca aatatcagga
     7561 tttcagcccg ttcaaaggat agcaaaattc tcttgagacg tttaatcatt gaccaaattc
     7621 gagaccagtt tgttcctttt agaatcaaag tgcatcaaga caaggcgtac aagctgtatg
     7681 atttgaaccg agttgctctt ttagaccact acacgtttga ccaagaaata gaggatattt
     7741 cgggctacat ttccccaaaa cagcaatgga gacttgacga tttttatgaa taattatatt
     7801 gatttagcaa aaacctatgg tggatttact agtctggata ccaactacct aaaccatcta
     7861 ttagccagtt tgacagacca gcaaaaacta gcttttatca caccaccacc aagtgttatt
     7921 aatgcctact ttgctgaaat ctaccaaaaa cagtcaccgc aagctgcgac tgattattat
     7981 tttaatcttt ctaaggcttt ggggcttttt actgaccaac catcttttga ggaagaaaag
     8041 ccctttgtac gcctcaattt gtctggaaaa gcttatggtt ttgcttacca aaatgaccaa
     8101 gaagttgcat tggtattttc tgaaaaagca gagcctaaga aacccgaact cttctttgaa
     8161 ttaacacaaa ttttcccaca atatatggtt tatgaagaca aaggccagct taaaatgcag
     8221 gctaagcagt ttgagcaagg agaatgtgaa gacattacgc ctgatgacac actcttgtcg
     8281 aagatttacc gtctggcaaa cggtatcacc atgcttaagg ggtttaatgt agaggagtta
     8341 tgggctctta gccaaacatt ttctggtcaa aagtattatg attttgccca acgagaattt
     8401 atgatttaca tcacccaata gaaagaatag attgaatgga attacaattt ttaggaactg
     8461 gagctggtca accagccaag cagcgcaatg tgtcaagtct tgccttgaaa ttactagacg
     8521 aaatcaatga agtctggatg tttgattgcg gtgaaggaac gcaaagacaa attttagaaa
     8581 cgacgattaa gccacgaaaa ataagaaaga ttttcattac tcatttgcat ggggaccaca
     8641 tttttggatt accaggattt ttatcaagtc ggtcttttca agctagtgaa gaacagacag
     8701 atcttgatat ttatggacca attggcatta aaacttacgt gttaactagt ctaaaagttt
     8761 ctggtgcgcg tgtaccttat cagattcatt ttcatgaatt tgatgacaaa tcattaggta
     8821 aaataatgga aacagataag tttgaggtct atgcagagcg tctggcgcat accatttttt
     8881 gcatgggtta tcgagtagtt caaaaagact tagaaggaac cctagacgca gaagccttaa
     8941 aagcagcggg tgttcctttt ggaccactct ttggcaaaat taaaaatggt caagacgttg
     9001 agttggaaga cggccgcctg atttgtgcca aagattatat ttctgcccct aaaaaaggca
     9061 aaatcatcac cattatcggc gatacgcgca aaacgtctgc cagtgttaaa ctcgctaaag
     9121 atgcagatgt tttggttcat gaatccacct atggtaaggg tgacgagcgg attgcgagaa
     9181 atcacgggca ttctaccaac atgcaggcag cacaaatcgc tcatgaagca ggcgcaaaac
     9241 gcctcttgct caatcatgta tcagctcgct ttttagggcg tgattgtcgc cagatggaaa
     9301 aagatgccgc cactatattt gaaaatgtta aaatggtaca agatttagag gaagtgatta
     9361 tttaatggca caaagaatca ttgttatcac gggagcttct ggaggactgg ctcaggcaat
     9421 tgttaagcag ttacccaagg aagacagctt gattttatta ggacgtaaca aagaacgcct
     9481 agaacactgt tatcagcata ttgacaacaa agaatgcctt gagttggata ttaccaatcc
     9541 agtagccatt gagaaaatgg tcgcccagat ttaccagcgc tatggccgta ttgatgtctt
     9601 gattaataat gctggctatg gagctttcaa aggctttgaa gagttttctg ccaaagaaat
     9661 agctgatatg tttcaggtta acaccctagc gagcattcac tttgcttgct tgattggtca
     9721 gaaaatggca gatcaggggc aaggccatct cattaatatt gtgtccatgg caggcttgat
     9781 tgcgtcagcc aaatcgagta tttattcagc caccaagttt gcccttatcg gattttccaa
     9841 tgcccttcgc ttagaattag cggataaagg ggtttacgtg accactgtga atccaggtcc
     9901 cattgccacc aagttttttg accaagctga cccgtctgga cattatttgg aaagcgttgg
     9961 taaatttact ctccaaccaa atcaagtggc taagcgtttg gtttctatta tcgggaaaaa
    10021 taaacgagaa ttgaatttgc cctttagttt agcggtgacc catcaatttt acaccctttt
    10081 ccctaaatta tctgattatc ttgcaagaaa ggtatttaat tataaatgat taaatccaaa
    10141 tatagctgga aaataaaaga caagaagcca gatgatggct tctttaagct agcaaagaca
    10201 aaaggtctaa cccagaccgc cgctcagttg atttatgatc gagggataag gactgaagaa
    10261 gccttagatg agtttttaac agcggacttg tctcaactgc atgatcctta cttgctacat
    10321 gacatgacaa aagctgtgcc aagaattcgt caagctattg aagagggcga acgaattctc
    10381 atttacggcg actatgatgc tgatggcatg acgtcggctt ctattgtcaa agaaacccta
    10441 gacatgatgg gagcagagcc tttggtttat cttcccaacc gctttacaga tggctatggc
    10501 cccaaccaga gcgtctataa atattttatt gagcaggaag ctgtgtccct aattatcacg
    10561 gttgataatg gcgtggccgg acatgaagcg attagatatg ctcaagaaca ggaagttgat
    10621 gtcattgtaa ctgaccatca tagcctgcct gaagaattgc cagaagcctt tgccatcatt
    10681 catcctgagc atcctgatgc tgattatccc tttaaacact tagctggctg tggcgttgcc
    10741 tttaaattgg caacagcttt gctagaaagt ttaccaacag actgtctaga cttggtagct
    10801 attggaacca ttgccgatat ggtaagcttg acaggtgaaa accgtgtttt agtcaaaaat
    10861 ggtctggcca tgctcaaaca caccgaaaga gtgggcttgc aggagttgat gtccttgtct
    10921 cctattgatt tggaacattt taatgaagac gccattggct ttcagattgc tccgcaatta
    10981 aatgctttag ggcgcttaga tgaccctaat ccagccattg agctactgac gggctttgat
    11041 gaccaagaag ctcaagcgat tgccttgatg attaagaaaa aaaatgaaga gcgtaaggcc
    11101 ttagtccaag acatttttga tcaagcgatg gctatggttg atcctcaaaa acctgttcaa
    11161 gtcttggcac aagctggctg gcatcctggt gttcttggga ttgtcgctgg tcgtatcatg
    11221 gaaactattg gacaaacggt cgtcgttttg accattgata atggctttgc aaaaggctcg
    11281 gccagaagtt tagaagctat taatattttt gaagccttga atggcaagcg tgagttattt
    11341 acagcctttg ggggacatgc tggtgcagca ggaatgaccc tgcccgttga caacttggaa
    11401 gctctttcag actttctttg tcagtttgtg atagaacgtg gcttagatca gactgccaaa
    11461 aatacgttaa ctattgatga aagcctgtct ttggacgacc ttagccttga tattttaaag
    11521 agtttagata aattagcccc ttatgggatg gatcatcaaa agccggtctt ttatgtcaag
    11581 gacataaggg ttagtcaagc gcgtaccata gggcaagacc agagccatct taaatttaaa
    11641 gtcagtcagg gcaaagcttc ctttgacgta ctggcttttg gtcaaggaag tcaactgcaa
    11701 gagtttcgac aagctactgg tttagaatta gcagttacct tatctgtcaa ccattggaat
    11761 gggaacacga gtctccaatt catgttagta gatgctcgtg ttgacggagt gcaacttctt
    11821 gatttaagga caaaaacagc caaagttcct gaaggtattc cgactattga agaagaccca
    11881 aatgccagag tcattctgat taatgacatc cctgaagatt tcaaaacctg gcgcaaccag
    11941 tttgttcaca aggattttga cgccatctat tttaaaaatc agatgaaaca tccttattat
    12001 ttaacaggat ttggcagcag agagcagttt gccaagctct acaaaaccat ctatcagttt
    12061 cctgaatttg atttacggca taaattgaca gagttgagtc actatttaaa catagaaaaa
    12121 cttttactga ttaagttgat tcaaattttt gaagagttgt cttttgtgac gattgacgat
    12181 gggctgatga cggttaatcc ccaagcgcaa aaacgagaga tttcagagag ccacatttac
    12241 caagacttaa aagaattggt gaaatttcaa gaaatcatgg ctttggctag cccgaaagag
    12301 atgtatgatt atttggtgaa atcaaacgat caataagtaa agcagttgac agtagttatt
    12361 gaggtagtta cgaatgaagt atcagataaa cataatgtca gaagtcttat tttacgaaaa
    12421 atatgtttcg tgatataatg aagagtattt tatatttggc aatttgccac tagaaagaat
    12481 taactatgga tttaacaaat tacattgcat cgatcaaaga ttaccctaaa gctggtatta
    12541 cgtttcgaga tatctcacct ttaatggctg acggtaaagc atatagctat gctattcgtg
    12601 aaatagcaca gtacgcttgt gataaagata ttgatatggt tgttggacct gaagcgcgtg
    12661 gttttatcat tggttgtcct gttgcagttg agttaggaat tggttttgct cccgttcgta
    12721 aaccaggaaa actgccaaga gatgttgtct ctgctgatta cgaaaaagaa tatggtcttg
    12781 ataccttaac tatgcatgca gatgctatta agcctggaca acgtgttttg attgtcgatg
    12841 atttactagc gactggcggt acggtaaaag caactattga aatgattgaa aaacttggtg
    12901 gtattgtagc tggttgtgcc ttccttattg aattagaagg tttaaatggt cgccatgcta
    12961 ttaggaacta tgactataaa gtcttaatgc agtttcctgg ataagcacat taatcagcat
    13021 ctgattaggg gatttaaagt agtaaaggct atagattcga ttttagcctt ttgattgagg
    13081 gattatgagt tttttagaac attataagtc aggtaatttg gttatcccaa gtgccttgct
    13141 ttttcattac aaagatcttt ttaagagctc agatgatttt ttggtctggc agtttttcta
    13201 tcttcaaaat acgacaaagc gagatgactt agcacccagt caaattgctc atgcgcttgg
    13261 aaaatcagtt gctgatatta ataaaatcat ttcatctttg actagtcaag ggcttttaga
    13321 tatgcggaca attgaactta ctggagaaat tgaaattatt tttgatgcga gtcctgtgtt
    13381 agccaagtta gatcaattgt ttgtcagtca aacggcaact gaaattgaca aacaagaaac
    13441 accaaaccat ttcaaacgat tagttgatga atttgaacgt gaattaggac gattcttgag
    13501 tccttttgag ttagaagatc ttgaaaaaac gcttcgtgat gataaaacag atcctgattt
    13561 gatacgagaa gctttaaaag aagctgtctt caacggcaaa acaaattgga aatatatcca
    13621 ggctatctta cgtaattggc gaaaagaagg tattgttaat cttcgacaag tagaagaacg
    13681 tagacgtgtt agagaaggcg aagatctttc tcaagtgacg atatcagagg attttctatc
    13741 tgcgatgaat ttatggagtg attcatgaga attggaaaag caagattagc aaaagtcctg
    13801 accatcattg gtcaaatgtt tcctgaggct aagggagagt tagactggga aacacctttt
    13861 caattgttga ttgcggtgat tttatcagct caaacgacag ataaggccgt caataaggta
    13921 actcctggac tatggcagtc ttatccagaa atagaagact tagcttttgc tgaactttct
    13981 gatgttgaaa atgctctgag aacgattgga ctctataaaa ataaggccaa aaatatcatt
    14041 aaaactgctc aggctattcg tgatgatttt aagggtcaag tgccaaaaac ccacaaagag
    14101 cttgaaagtt taccgggtgt tggccgaaaa acagccaatg tggtattggc agaggtttat
    14161 ggtgttccag ctattgcggt tgatactcat gtggctagag tctcaaagag gctcaatatt
    14221 tcatcaccag atgccgatgt caagcagatt gaagcagatt tgatggctaa aattccaaag
    14281 aaagattgga ttattactca ccatcgattg attttctttg gacgctacca ttgtttagcc
    14341 aaaaaaccaa aatgtgagat ttgtcccgtt cagtcttact gcaagtacta tcaaaatact
    14401 tatggaaaat cgaaagccta gcctttggtt ttcttttttt atggaggtaa ttttgctata
    14461 atagaaccat tacgttttag aaagaaatca agatggatag tcaattatca aaccgtttag
    14521 cccaagttgc ggcctatgtt ccaaaaggtg tcaaattatt agatgttggc agtgatcatg
    14581 cctaccttcc catatttttg gtagaaacta atcagatttc agcagccatt gctggcgaag
    14641 tggttagggg tccctacgaa tctgctctta aaaatgtcac acagtctggc cttgccgagc
    14701 atattcaggt gcgcttagcc aatggccttg cagcctttga agaagctgat gatgtgacag
    14761 ccattaccat ttgtggcatg ggtggccgtt tgattgctga tattttagag gcaggtaagg
    14821 aaaaattgca gggcattgaa cgtctggttt tacaacccaa caatcgtgag gatgatttac
    14881 gggcttggtt atcggttaac gcttttaaaa ttgttgcaga aaccatcatg gctgaaaatg
    14941 acaaatatta tgaaatcatc gttgctgagc atggtgaaaa ggccttatcc gcgacagaat
    15001 tgcgttttgg tccatacctt tctcaggaaa aatcagtcgt ttttaaagag aagtggcaac
    15061 gagaaatgga taagttagct tatgccttgt cctgtatccc agaagaaaaa actcaagagc
    15121 gtcagcttct cttgacaaaa atacaacaaa taaaagaggt gattgttcat gaaagctaaa
    15181 accctaattg atgcctatga agccttttgc ccacttgatt tatctatgga aggagacgtt
    15241 aaaggtcttc aaatgggttc attggataaa gacattcgta aggttatgat tactttagat
    15301 atccgagagt caacagtagc agaagccatc aaaaatgaag ttgatctcat tataactaag
    15361 catgctccca tctttaaacc gcttaaagat ctggtttcat cccctcagcg tgatatcctt
    15421 ctagatttgg tcaagcatga catttctgtc tatgtgagcc ataccaatat tgacattgta
    15481 ccaggtgggc taaatgattg gttttgtgac ctgctagaaa tcaaggaagc aacttacttg
    15541 tctgaaacca aagaaggctt tggcattggt cgtattggaa cagttaaaga acaagcgtta
    15601 gaagagttag caagtaaggt caaaagggtg tttgatttag ataccgtgcg acttatccgt
    15661 tacgataagg aaaacccttt gatttcaaag attgctatct gtggcggaag tggtggtgaa
    15721 ttttatcagg atgctgtgca aaaaggcgca gacgtttata ttacagggga tatctattac
    15781 catacagcac aggagatgct gacagaagga ctatttgcgg ttgacccggg gcatcatatt
    15841 gaggtgcttt ttacggagaa attaaaggag aaactccaag ggtggaaaga agagaacggt
    15901 tgggatgtca gcattatttc aagcaaagcc tcgaccaatc catttagcca tttataggct
    15961 gttaaggtct taaaataaga taaaaggata ccaggaatga aaatagccat tattggggcg
    16021 gggattgtag gatcaaccgc cgcttattat ttacaacaaa gtggtcaaaa agaagttacc
    16081 atttttgacc atggtcaagg acaagccact aaggctgctg ctggtattat tagtccttgg
    16141 ttttcaaagc gtcgcaataa agtttggtac cgcatggctc gtttaggagc ggacttttat
    16201 cagcaattaa tcaatgacct caaagaagat ggttttgcaa cagattttta tcagcaaaat
    16261 ggcatctatg ttttaaaaaa gcaggaagaa aaactaagag atctttatga attagcgtta
    16321 gcaagaaagg tagaatcacc gattattggt gagttagcca ttaaaaatcg taaagaactg
    16381 gggaatgatt ttaaaggatt gattggcttt gataactgtc tgtacgcttc aggagctgct
    16441 agagtggagg gagccgcttt atgtgagacg ttactcaagg ctagtggtta tccagttatt
    16501 cgccaaaaag tcactctgaa acagcaagga agtggttatg agattgctgg tcattatttt
    16561 gatcaggtca ttctggcagc aggagcatgg ctacctgact tattgaggcc tttaggctat
    16621 caggttgatg tgcgaccaca aaagggacaa ctcttggatt atgacgttca tcacatcatc
    16681 agcgacactt atccagttgt tatgccagaa ggtgaaatag atcttattcc ttttaaccaa
    16741 ggtaagattt ctgttggtgc gagccatgaa aatgataaag gttatgattt ggagcctgat
    16801 tggcaggtct tagaaaaaat tgaaatgcaa gctctcactt atttgccgtt attaaaagaa
    16861 gctactcaaa aatcatgtcg tgtagggata agagcttata ccagtgatta ttctcctttt
    16921 tatggtcagg ttccaggatt gaagaacctt tatacagcta gtggtttagg gtcatcggga
    16981 ttaacagttg gacctttgat tggctatgaa ttagctcaat tattgctagg acacgaagga
    17041 cttttgacgc ctagcgacta ttcccctgag ccttaccttt tgcggtctac tggtaaagcg
    17101 tgacactgct ttcaaaaaat gatagaatga tagggtatat agaagaatag gagcactact
    17161 atgaaaggta ttattcttgc aggaggttca gggacacgct tgtatccact gacccgtgcc
    17221 gcatctaaac agttgatgcc catttatgac aaaccaatga tttattaccc attgtcaacc
    17281 ttgatgttgg cagggattaa agatatttta atcatttcaa ctccccaaga tcttcctcgt
    17341 ttcgaagaat tgctaggaga cgggtcagaa tttggcatta gcttatccta taaggaacaa
    17401 ccaagcccag atggtttagc acaagctttc attattggag aggagtttat cggtgatgac
    17461 cgtgttgctc ttattttagg agataatatt taccacggta atggcctcac taaaatgctt
    17521 caaaaggcag ctgccaaaga aaaaggagcc accgtttttg gttatcaagt gaaagaccct
    17581 gagcgctttg gagtggtgga atttgatgag aacatgaatg ctatctctat cgaagaaaaa
    17641 ccagaagtac ctaagtccca ctttgcagtg actggacttt atttctatga caatgacgtg
    17701 gtagagattg ctaaaaacat taaaccaagc gcgcgtggtg agttggaaat tacagacgtc
    17761 aacaaggctt acttggatcg tggtgacctc tccgttgaat tgatggggcg tggttttgca
    17821 tggctagaca ctggaacgca tgaaagtcta cttgaagcgg ctcaatatat tgaaactgtt
    17881 caacgcttgc aaaacgctca agtggcaaat ctggaagaaa ttgcctatcg catgggttat
    17941 atcagtaaag aagatgtcca taaattggcg caatctttaa agaaaaacga atacgggcaa
    18001 tacttgcttc gtttgattgg agaagcttaa tgacagaaac tttttttgac aaaccattgg
    18061 cttgccgaga aatcaaagaa atcccaggct tactagagtt tgatattcct gttcgtgggg
    18121 ataatcgtgg ctggtttaaa gaaaatttcc aaaaagaaaa aatgttgcca attggctttc
    18181 cagaacgttt ttttgaggaa ggaaaactac aaaataacgt ttctttttca cgtcagcatg
    18241 tgctgcgtgg acttcatgct gaaccttggg ataaatacat ctcagttgct gatgatggca
    18301 aggttttagg agcatgggtt gatcttcgtg agggagagac ttttggaaac gtctaccaga
    18361 cagtgattga tgcttcaaaa ggaatgtttg ttcctagagg ggttgctaat ggctttcaag
    18421 ttctttcaga gactgtctct tacagttatc ttgtcaatga ctactgggct cttgacttga
    18481 aacctaagta tgcttttgta aactatgctg acccaagtct tgggattact tgggaaaatc
    18541 tagcagctgc agaagtttct gaagcagata aaaaccatcc tcttcttagt gatgtcaaac
    18601 cactgaaacc aaaagaccta tagggaaaca acatactcag atgattggga ttaatcattt
    18661 gaggtggata tgagaggagt tattcttctc tacttcaggt aacaagtaac aactaaaaat
    18721 gatgaaagga aagttcagtt tctctctttg agctgaacat gggactcaaa tcttagaaag
    18781 caatgttttc ttaggcctaa aacgtctttg ttagagtcat tacttttaat agattttttc
    18841 ggaaacgaaa ggtctcttta tatcttatgt ataaaaatat tatcgtaact ggtggagctg
    18901 gtttcatcgg ttctaacttt gtacactatg tctacaataa ccacccagat gttcatgtaa
    18961 ctgtccttga taaattgaca tatgcaggta accgtgctaa cattgaagct attcttggtg
    19021 atcgtgttga gttagttgtt ggtgatatcg ctgacgctga attggtagat aaattggctg
    19081 ccaaagcgga tgctattgtt cactatgcgg ctgagagcca caacgataac tcattggaag
    19141 atccaagtcc atttatccat acaaacttta tcggaactta cactttgctt gaagcagctc
    19201 gtaaatacga tatccgtttc caccacgtgt caactgatga agtttatgga gatcttccac
    19261 ttcgtgaaga ccttccagga cagggcgaag gaccaggtga aaaattcact gctgaaacaa
    19321 aatacaatcc atcatcacct tactcatcaa ctaaggcagc ttctgacctt atcgttaagg
    19381 catgggtacg ttccttcggt gtgaaagcga ccatttcgaa ctgttcaaat aactatggac
    19441 cataccaaca catcgaaaaa ttcattccac gtcaaattac aaatatcttg gcaggaatca
    19501 aaccaaaact ttatggtgaa ggtaaaaacg tccgtgactg gattcatact aatgatcatt
    19561 ctacaggagt atgggctatt ttgactaagg gtcgtatcgg tgaaacatac cttattggtg
    19621 ccgacggcga gaaaaacaac aaggaagttc ttgaattgat tcttgaaaaa atgggtcaac
    19681 caaaagacgc ttatgatcac gtaactgacc gtgctggtca cgatcttcgt tacgctattg
    19741 attctacaaa attgcgtgaa gaactcggct gggaaccaca atttacaaac ttttcagaag
    19801 gtttggaaga aactattaag tggtacacag aaaatgagac atggtggaaa gcagaaaaag
    19861 atgctgtaga agccaagtat gctaaaactc aagaagtgat taaataaaac attaaagaac
    19921 cttgtcatat caacgtttgt tgaagatgtc aaggtttttt cttgtgtttt ggggcatttt
    19981 tggggcatat tatagccgat ttaagatgtc gacgacttca tttttcatgc ttttcgtgac
    20041 gtgggtatag atttgttgag tagttttcga gtcagcatgt ccaactctat ccatgatagt
    20101 ttttaagggc actttgtttt ctgcaaggcg actcaccagg gtatgacgga agatgtggct
    20161 ggtgagttct ttttgaatcg gtttttctag tctcttattt gccgctctga tagaggtgtt
    20221 gagggcgttg tcttgaatag gaacaccatt tctggaaatg aagatgtagc ccatgtcctt
    20281 gtaattagga ttagtatttt tttcaagagc attaattttc agtatatcct gaataatttc
    20341 tttttcacgt ttggttatca atgtttcacg ccaactggaa tttgttttag gggtggtttt
    20401 gatagcgttt ctatagccat ttgaggtgta gtcaagagtt ccgtggattt caatgatatc
    20461 atttttgata ttgtctggct gtatagctag agcttctcca atgcggcagc catttaagct
    20521 cataaattct gccagataag ccattttaat cgatccttta cgtctataca tttcatctaa
    20581 tagccttttg agttcatctt tttctaaaaa cttctgggca acgtcttcaa agtctttgat
    20641 ggtcttaaca ggttttgcga gttgggtact aataactgga ttgattgaga catactctaa
    20701 agcgatagcg tagtcgaagg tttgtttgag cagctgccgt gctcgtttac gtttgtcata
    20761 actacctggt attttgtcga taatactttg caggtatttc gtggttatct tggcaatcat
    20821 cacttctgga tcaattaagt ttcgcaattc tcttattcta aaatcaagag agcggacaga
    20881 agttgatttg agtgatttct gatgatgttc ccaccattcg ttcatgacat ctagtaggta
    20941 ggcatcggtt gtggtaagac ttgttaagat tttagatatt ttttcgtcaa gatatttttg
    21001 ggcttctttt cgtattcgtg gcgtgtcttt ttccataagg acagaagctc tgcaccactt
    21061 gccagtatac gggtgtttgt accgttctac aaaatttact tttccgcttt tgtgtttttc
    21121 tgaccacatt gttttttacc tcattttctg ttaaaatagg tatagtaaag agacctactg
    21181 cgaagcaggt ttttactatt accaacttga cctacacgtt tgcttgccgg cgctgtgtag
    21241 gtcttttttt aatttgcttt ttttatattt attgtatttt ctgggactgc taatccatta
    21301 gagtagaaaa tatactctat tcctttactt ggttttgtta ctgaatagtt caggtaatat
    21361 ttttcatact taaattcttt atacatttga aaaatttctt cagataaatc ataagtgaga
    21421 atccaatttt tatttgacat ataatgttta attgtactgg acagactatg atgattttca
    21481 tgattgtaaa agtttgtata taatcctggt ccttttgtgt aatatggagg gtcaaaaaaa
    21541 gtgaaagaat tttttgtttt ggtgatattt aaacgaatga acttttcagc atccatatta
    21601 taaagtttaa tttgtttttt ataagaggca attagcttta tttttttaat agttttttct
    21661 ttgttgaaac ggcaatctaa tttatagttc ccatcttgtt ttaacccacc aattacacca
    21721 gcttttatga tacctgagcg atttgttcga ttgaggaata aggttgagaa acctaaggtt
    21781 agcaagtcgt cacaattatt tttatttttt tggacttctc tttgaagttt ccactcatca
    21841 atggtgatag gagtagtatt tattttttcg attagctgtt ccgtataatt taatactgaa
    21901 taccaaaaag catagatagc tttgtcatag tcgttaacca tgattttatg aacattgtta
    21961 tttaagagta actttaaggc tattcccatc cctcccatat agggttcaat ataggtgatt
    22021 gcatcattag ctataacgag ttctcttaca taatcataaa cttgagactt accaccggga
    22081 tatcttaacg gactaatgtt tttcataagc tattcctcct ttccatatag aatacactat
    22141 ttttttaaag ttggccagta ataaatggcc aacttgaagt aggattgata ttataaaacg
    22201 gtgcggtctt atgaaaagct atttttaagt tgtcaaaaaa tttcaatacc tcatcttgat
    22261 tattagtatc atctatccaa tatttcataa cataattcca aaaatttgtg tcacaattat
    22321 agatcttttt attttcttct ctttttacac cgtggtgaga accaggttga tttaattttg
    22381 cttctagttc atcaagttga gtaataaaag attcttgaac aagttttttc gtatatcctg
    22441 ctgcgataat atcttgcttc tgccaaaaat tgtagtcatc taataagact tctttaagat
    22501 acttaaaaat aagttcttct ggagaataat tccctggtag actaaataaa ttgtgtgtta
    22561 aatattgctg acctaattgt tcatcaccgt cagtgattga tatgattctt agtgatgact
    22621 gattggtata tctatcttgg gctagtgcct ttatcgccga agaggatatt ttagcatcta
    22681 ttatgtggaa gaatgattct agtgataatt ggtatctttc aaaatatgct tgaagtaaat
    22741 tttgaaaaaa atctttagct tcgttatctt ctaataaaac aggtataggt tgcttgacat
    22801 atacattgtt cactaattta ttttgtaaca aggcattaat tgagtattta ttgagatgtt
    22861 ttaataaatc aaca
//
LOCUS       DAUCXI010000029        22505 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.029, whole genome shotgun sequence.
ACCESSION   DAUCXI010000029 DAUCXI010000000
VERSION     DAUCXI010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22505
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.029"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            61..336
                     /locus_tag="VGY43_001218"
     CDS             61..336
                     /locus_tag="VGY43_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEQ4302401.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFTSPGTIGAPDRIVVMNTGIFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDMALKEMENWV"
     gene            333..1655
                     /locus_tag="VGY43_001219"
     CDS             333..1655
                     /locus_tag="VGY43_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEQ4302402.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIGKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGARLETSQTRFKDKYFVPDKRNGLIIYSWALRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNNVVSVKLSNMKAYKQLEADLVLEFKNKEISAANSAVLAN
                     KLLQMANGAIYDDDKATVAIHDDKLDALENVVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            1656..1823
                     /locus_tag="VGY43_001220"
     CDS             1656..1823
                     /locus_tag="VGY43_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302403.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLKFWNSCEAT
                     VKEKYTREWKK"
     gene            1820..2086
                     /locus_tag="VGY43_001221"
     CDS             1820..2086
                     /locus_tag="VGY43_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302404.1"
                     /translation="MTEELIKPLLEEIERKDDRLYMQSNVIAVLMTAVLMLLMISIVL
                     QNHYEPQITGLRAQLSRTQKQLKRASEDRARQTKRIVELTGNGG"
     gene            2237..2428
                     /locus_tag="VGY43_001222"
     CDS             2237..2428
                     /locus_tag="VGY43_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302405.1"
                     /translation="MKIEFFLKQGPTKSVSNYGEICIDEVIGAMKNNDVIALNGKNNA
                     VIIPKQNISHVIIHKEVTG"
     gene            2425..2841
                     /locus_tag="VGY43_001223"
     CDS             2425..2841
                     /locus_tag="VGY43_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEQ4302406.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            2931..3383
                     /locus_tag="VGY43_001224"
     CDS             2931..3383
                     /locus_tag="VGY43_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEQ4302407.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            3373..4650
                     /locus_tag="VGY43_001225"
     CDS             3373..4650
                     /locus_tag="VGY43_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEQ4302408.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAD
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLSSFFGLDYGFINDPSAFLHV
                     KIDDANKKLYVIEEYVRKNLTNDKIANAIKDLGYTKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWVVDERCVKTIEELENYTWKKDKKTNEYTNEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            4666..6199
                     /locus_tag="VGY43_001226"
                     /pseudo
     CDS             4666..6199
                     /locus_tag="VGY43_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            6159..7607
                     /locus_tag="VGY43_001227"
     CDS             6159..7607
                     /locus_tag="VGY43_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEQ4302409.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQEDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDVAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            7635..7823
                     /locus_tag="VGY43_001228"
     CDS             7635..7823
                     /locus_tag="VGY43_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302410.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            7828..8094
                     /locus_tag="VGY43_001229"
     CDS             7828..8094
                     /locus_tag="VGY43_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302411.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELAAVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK"
     gene            8262..8831
                     /locus_tag="VGY43_001230"
     CDS             8262..8831
                     /locus_tag="VGY43_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEQ4302412.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEYPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            8844..9731
                     /locus_tag="VGY43_001231"
     CDS             8844..9731
                     /locus_tag="VGY43_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEQ4302413.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            9743..10099
                     /locus_tag="VGY43_001232"
     CDS             9743..10099
                     /locus_tag="VGY43_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEQ4302414.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            10110..10388
                     /locus_tag="VGY43_001233"
     CDS             10110..10388
                     /locus_tag="VGY43_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302415.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            10385..10729
                     /locus_tag="VGY43_001234"
     CDS             10385..10729
                     /locus_tag="VGY43_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEQ4302416.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            10733..11092
                     /locus_tag="VGY43_001235"
     CDS             10733..11092
                     /locus_tag="VGY43_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302417.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            11104..11703
                     /locus_tag="VGY43_001236"
     CDS             11104..11703
                     /locus_tag="VGY43_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEQ4302418.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESTGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            11757..12212
                     /locus_tag="VGY43_001237"
     CDS             11757..12212
                     /locus_tag="VGY43_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302419.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAESVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDMDATQIQIIEDMIGRMSNAVS"
     gene            12287..12520
                     /locus_tag="VGY43_001238"
     CDS             12287..12520
                     /locus_tag="VGY43_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302420.1"
                     /translation="MEGLEYKQLAERESLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            12535..16917
                     /locus_tag="VGY43_001239"
     CDS             12535..16917
                     /locus_tag="VGY43_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEQ4302421.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVTDKIRGNLTGFINQTKMQLQNLVGIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGQQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFSQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSALSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINTVLRDFAHTGELSGQAFDNLKAKITSLAPKVIALWA
                     VMNPASAISTIMPLLSLFGKVALALGSLGTSVGAFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IEQLLNTAVTKGPGIIQGLVKGITSKIPVLIASGTQLIAKFANAITVLLPVIIQAGVQ
                     LITSLVQGIGQNATNLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIDSFGNSLQANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIAQSAVQIIQFLASGLTQALPQIIAAG
                     IQLVAQLAVALIKGLPQIISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATVMAMNVGMQTTAIANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLRGLNDSMSLASGISANMSVANINATTQAREMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFD"
     gene            16929..17771
                     /locus_tag="VGY43_001240"
     CDS             16929..17771
                     /locus_tag="VGY43_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ4302422.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTISNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            17781..19760
                     /locus_tag="VGY43_001241"
     CDS             17781..19760
                     /locus_tag="VGY43_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEQ4302423.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGDPNRVKTYDQDYIEVEANDGGFKRGETYTISFSQTCELLKEVAITLTQINN
                     KGVKLVLTPTKAKMDAQTFEVTKDKQSIEVYPLSYTGVLTGDWYKPKQIDLNASDTQE
                     LALEMDYKDVVDGKDATITGAWSDSPQIILYGGKK"
     gene            19757..20872
                     /locus_tag="VGY43_001242"
     CDS             19757..20872
                     /locus_tag="VGY43_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEQ4302424.1"
                     /translation="MTETIPLRVQFKRMKAAEWASSDVVLLEGEIGFETDTGFAKFGD
                     GQNTFSKLKYLTGPKGPKGDTGLQGKTGGTGPRGPAGKPGTTDYDQLQNKPDLGAFAQ
                     KEETNSKITKLESSKADKNAVYLKAESKIELDKKLNLKGGVMTGQLQFKPNKSGIKPS
                     SSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNQSALFVDYSGKTNAV
                     NIAMRQPTTPNFSSALNITSGNENGSAMQIRGVEKALGTLKITHENPSVEANYDENAA
                     ALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLGDDKFYVKSDGGFYAKKTS
                     QIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            20887..>22505
                     /locus_tag="VGY43_001243"
     CDS             20887..>22505
                     /locus_tag="VGY43_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEQ4302425.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDIENSKLWSKIKVN
                     NRGMLQEYYDGTIKTEIINSAQGVATRISEDTGKKLALINDTINGIRREYQNADKKLS
                     ASYQAGIDGLKTTMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ENKLNGLRAEFTRSNQGMRTELESKISGLRTAQQTTANQISQEIRNREGAVSRVQQDL
                     ASYQRRLQDAEDNYSSLTHTIRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYRGS
                     ALYASIGITSSGDGIDSASSGRFCGVRFFRYA"
BASE COUNT         7509 a         3952 c         5023 g         6021 t
ORIGIN      
        1 aagaattaat aagttgaaaa aaaaacgtaa ccctgacctt tattgaccaa agggggaagg
       61 atgaggactg aaaaagatat tgaaaattat ttgaaaaaga aaacaaaagg gctgtgttta
      121 aaattcacca gtccagggac gataggagcg cctgacagaa ttgttgtcat gaatacggga
      181 atcttttttg tagaggtcaa agcgcctggt aaaaaaccaa gacccagcca agttgccatg
      241 cacaaaaaaa taaaagaggc tgggcagcac gtttgggttg ttgactccta cgaatcagtg
      301 gacatggcct taaaagaaat ggagaactgg gtgtgagact gcacgagtac caagaatacg
      361 ctaagacatg gatagtagag cacccttatt gtggcctttt acttgacatg ggccttggta
      421 aaacgctgac aacactatcg gcgatagatg agattcaaaa tattttttcc gaggatcata
      481 agattttaat cgtagctcct aaaaaagtgg cggaagaaac gtggccaacg gagattggga
      541 aatggcattt tgatttcacc tactctaaag ttttggggag tgagggaaaa cgaattgaag
      601 ccttagaaac agaagccgat atctatttga ttaatcgtga gaatgttact tggcttgttg
      661 aatactacaa gactaaatgg ccgtttacct ttgtggttat tgatgagctg tcaagcttta
      721 agtctagtaa gtcaaaacgg tttagggctt tgcgaaaagt tagaccgaaa gtccaacgtc
      781 ttgtaggact aacaggaacc ccagcgccta acagtttgat tgatttgtgg ccgcagattt
      841 atctgatgga cagaggcgcc agacttgaga cgagccagac tcgatttaaa gacaagtatt
      901 ttgttcctga taagcgtaat ggcctaatca tttacagttg ggcacttagg gatggtgcag
      961 aagcagaaat ctataacaag attgaggaca tctgtgtcag catgaaagct aaagactatc
     1021 tcaagttacc gccgcgaacc aacaacgttg tatcagttaa gttatctaat atgaaagcct
     1081 acaaacagct tgaagctgat ttggtgttgg agtttaaaaa taaagaaata tctgcggcta
     1141 attctgcggt tttggccaat aaattacttc aaatggccaa tggtgctatc tatgatgatg
     1201 ataaagcaac agttgctata cacgacgaca aacttgacgc gcttgagaat gtcgttgaag
     1261 aaagccaagg tcagccaatc ttagtttttt accagtatca acatgatctt gaaagactta
     1321 agaaacgatt tcctcaggct gaagagctga cgtcggttga caagtggaat tccggaaaaa
     1381 taccaattct tctgtgtcac ccacagtcag ccggacatgg gcttaatctt caaaaaggcg
     1441 ggcatattat tgtttggttt gggctaacat ggagtcttga atattatcaa caagctaatg
     1501 ccagattaga tagacaaggg cagacagaac ccgttattgt acaccacatt gttgcagaaa
     1561 atacagttga tgaaaaagta cttaggattt tacaaggcaa agaaaaaaat cagaacgcct
     1621 tactcgaagc agttaaggcg cagttaggag tctagatgaa aaaagaatat gtcgttagaa
     1681 tctacacggg tagagaaaag aattttgagg caaaacctca gtttgaagag aaaaccttta
     1741 cgcgaaaagc ggacatgttg aagttttgga attcttgcga agcaacagtt aaagaaaaat
     1801 atactaggga gtggaaaaaa tgacagaaga actaataaaa ccgctgctag aagagataga
     1861 gcgaaaagat gatagattgt atatgcagtc taatgtaatt gccgtcttaa tgacagcggt
     1921 tcttatgtta ctgatgataa gtatagtctt acaaaaccac tacgaaccac aaataacagg
     1981 actgcgtgct cagctaagta ggacacaaaa gcagcttaaa cgtgctagtg aggatagggc
     2041 cagacagaca aaacggatag tggaattgac gggtaatggg gggtaggtat gaatataatc
     2101 catagaatgg aaaacgggat agatgctgta ggtgatttaa caacttatgc agtaccatgt
     2161 tgtccagagt gtaaaaatga aacatatagt cagaaacact gtcctttttg cggtgaaaat
     2221 cttatggagg tagcaaatga aaattgaatt ttttttaaag caaggtccta ctaagagcgt
     2281 ttctaattat ggtgaaattt gtattgatga agtaattggc gcaatgaaaa ataacgatgt
     2341 cattgctcta aatggaaaaa acaacgcagt tattataccc aaacaaaata tttctcacgt
     2401 aattattcat aaagaggtaa cgggatgagt agattatcta atgcacagct aaaggctttt
     2461 gatgaatggt tgtttgatta tcgttttatt gataacaaga ttgcacttcg aaaacttgag
     2521 ctacaaactg atatgaatac agaagtagat aaaaatatcg gtggaggaag agcaaatttt
     2581 gtttcaaaag ttactgagga tgtggttgca aggtgggatt cagataggga actaaagggt
     2641 ctatccaatt tcaaagaagc agttattgca acgctaaatc ttttggatga agagctaact
     2701 gatattttta atcttaggtg gggtgttggt tcaagtaaca cttgggaaga aattgcctat
     2761 acaagacatc tgtcacgtaa gtctatttac cgcaaaagag agcggattct agaaatattc
     2821 tccaaaaaaa taggaatgtg acacaaaaat gtatggaatt gtcatctttt tgatgataaa
     2881 ttgatagtat gagtttaaag gtaaggcaaa tagtgtcttg cctttttgtt atgcttggag
     2941 gtgatggaaa attgagtaaa ttaaccctaa aacagaagcg ttttgcagat gagtacatca
     3001 tctcagctaa cgcgacagca gctgctatta aagcagggta tagtaaaaag acagcaaggt
     3061 caataggtca agaaaacttg accaaacctg acattaaagc ttatatagac gagcggcttg
     3121 aaaaacttga atctgaaaag attgctacgc aagaagaagt cctacaatat ctcacttcaa
     3181 ttatgcgagg agaccaacaa gaaaagacgc tcattagcgt tggagagttt ggccagaaga
     3241 tagttgacat cgatgttggt gccaaggata gaatcaaggc agctgagcta ctaggcaaac
     3301 ggtacaggtt atttactgac aaggttgaaa tggatgtcag ctcagatgta accattaacg
     3361 taggtgagtg ggatgacgac taaacagcgc cctaaaatta atatcgtaat caagcatcct
     3421 agcaaagttt ttaacaagca tatctacgac aaactttaca actatagcaa cttcacggaa
     3481 gttcattatg gtggggcgtc tagcggaaag tctcacggtg tttttcaaaa gataatttta
     3541 aaagcactta accccaaatt caaacatccc agaaagatat tagttctcag aaaagtcggt
     3601 gcaaccgtta gagactctgt atttgctgat atcatgtcta atttgtcgta tttcggcatc
     3661 ttggataaat gtaagataaa tatgtcggct tttagaataa cgctcccgaa tggctcggaa
     3721 ttcattttta agggtatgga taaccctgag aagattaagt caattaaggg gatatctgat
     3781 gtcgtcatgg aagaagctag tgagtttacg cttgatgatt atacgcagtt gactttgcgt
     3841 ttaagagata agaaacatct agagaagcaa atatacttga tgtttaaccc tgtgtcaaaa
     3901 gtaaactggg tttataaagc cttcttcgtt aagacaccta agaatacagt tgtctatcaa
     3961 acaacttata aagacaaccg cttcttagat gatgtcacga gagaaaatat tgaggaacta
     4021 gccgatagga atgaagctta ctacaaaata tatgctcttg gccagtttgc tacacttgat
     4081 aaactaattt ttcccaaata tgacaagcaa atattaaaca aagacaagtt atcacacttg
     4141 tcttcttttt ttggtttgga ctatgggttt atcaatgacc cttcggcatt tttgcatgtt
     4201 aaaatcgatg acgcaaacaa gaagttatac gtcatagagg aatatgtcag aaagaatttg
     4261 accaatgaca aaatagcaaa tgctataaag gacctcggct ataccaaaga agaaatcaga
     4321 ggagattcgg ctgaaaagaa atctaatcaa gagctgagga atttaggtat tcctagaatg
     4381 attgatgtta ccaaagggcc tggaaccgtt atgcaaggaa tacagtattt gcttcaatat
     4441 gattgggttg ttgatgaaag gtgtgtcaag actattgaag aactcgaaaa ttacacttgg
     4501 aagaaagaca agaagactaa tgagtatacc aacgaaccag ttgacagcta taaccactgc
     4561 attgatgcca taagatatgc cgtacaagac agaatatacc agtcggcgga tagaagtaag
     4621 cgcatgaaaa atgctaaata ttatttttag gaatgaggtg aaactttgga agaaaaacaa
     4681 tttttagcag gaactcgttt taatgagaat gctaataagc aatttattat gctgcaagaa
     4741 gactttgaag caattgacta tgaatcaaaa ctttggatag atcaacttaa gaattacatt
     4801 tcaaggttta aagcagaaca attagagcgt ttgaaagagt taaagcgata ctatcttggg
     4861 gataataaca tcaagtatag acctgctaaa acagataaat acgcagcgga taatcgtatt
     4921 gcaagtgatt ttgctaagta tattacggta tttgagcaag gttatatgct tggcgttccc
     4981 gttgagtaca aaaatgaaaa taaagacctc caggcagcta ttgaccttat gtcggtcaga
     5041 aacaatgagg actaccacaa cgtcaaaata aaaacagatt tatcaattta tggaagagtc
     5101 tacgagctgt taactgttga gaaaatagat gacaaaaaaa accgaagtaa aactctacca
     5161 gctcccggcc gagcaaactt ttgttatcta tgatgataca taccagcgaa attcgttgat
     5221 ggccgttcat ttctacgaca tagattacgg ctcaggtaaa cgtaaacaga ttatcaaagc
     5281 atatacttcc gacacaattt atacctacga agactataac cttgaaacaa aaggtatgcg
     5341 attaaaagat tatgaaggac atttttttaa aggtgtacca gtcaacgaat acgctaataa
     5401 cgaggagcga acgggggctt atgagtctgt acttgataat attgacgcct atgatttatc
     5461 tcaatcagag cttgctaact ttcaacaaga ttcagtcaat gcgttgcttg taatagctgg
     5521 taatgcttac acaggagctg atgagaatga ctacttagat gatggccgat taaatcctaa
     5581 tggtcgttta gcgatctcaa ttgggtttaa aaaagcccaa gtgttaattt tagacgataa
     5641 tcctaatcca aatggcgtta aaccgcaagc gtactttctc aaaaaagagt atgataccgc
     5701 cggtagcgaa gcctacaaaa atagattagt tgcagacatt ttgaggttta cttttacgcc
     5761 agatacacaa gatatgaaat tttcaggagt tcaatctggt gaatcaatga agtataagct
     5821 tatggcttct gacaactatc gcgagaagca agagaggttg tttaaaaaag gattaatgcg
     5881 acgcttacgc ttagcagcta atatctgggc catcaaaggg aatgaagcaa ctacatatag
     5941 ccttgtaaat gatacgagta tagttttcac acctaatctt cctcaaaacg ataatgaaat
     6001 tgttacagct gcacaaaatc tttatggcat tgttagcgat cagactatct ttgaaatctt
     6061 aaatactgtc acaggagtag atgctgaagc agagcttaaa cgcttgaaag aagaagctga
     6121 taaaaagcaa tctttaccgg agcctagatt ggtaggtgat gctagtggtc aagaagaacc
     6181 aacggcagaa aagccttaat tactggcaaa agcgtcaaga agatattcta agttatttag
     6241 acagaactga tttagatgtc ttttcagaac tgcagaagtt atataatgaa caggcttttg
     6301 agttacaaaa ggaattgttt gatttttata ctaagtattc tgaagagaac aaaatgactt
     6361 atcaggatgt cgttaaaaaa ctacgtcatg aagatttatc agattacgta gctaatgcta
     6421 acaagtatcg taaacaagct gagaaagatc ctgagctgct aaaacgactt aatgagcagt
     6481 atgtatcagc aagagctaca aggatggatg cattaaatct tgagcttgtt tatcgtgcgg
     6541 ggatactaaa aggtgtactt gattcagcat ttgaaaatca tttaaaaaaa gttgcctcat
     6601 atgcttataa aaaagcaatg ggtggacggt cagggacaat caatggtcca gttttagaag
     6661 aactggttag aaccccgttt gatggttata actattcaga acagttgtgg ggcaatactg
     6721 acaatcttgt taagaatctt caaaagagat taaaacaagg ttttgttcgt ggcgagcatc
     6781 ctagagcgat ggccagagat ttagctaagc gatttaatgt tgctaatcac agggctgaaa
     6841 cactaatcag aactgatgga actatggtga ttaataatgc taccgctagg cgctacttga
     6901 atgcaggact taagtattat cgtgatttag ttagacttga tgacaggaca actgagatat
     6961 gccgtacaat tgctaaagaa aacaaaagaa agctattatc tgagctaaag cctggaatta
     7021 atgtagcacc ctatcatttc aactgcagaa caactattat tcctgatgaa gatgagctaa
     7081 gtattgaagt agaaccaatt gatgataaaa gcactaagta ttttaaggat gtcacctcag
     7141 attggataga tggaaatgag cataaaccac aactgtcact actaaatgag tacgtaaaaa
     7201 atggcactcc ttacaaagta gatggccata gtgtcgttct tgatcattcg aattatgaat
     7261 atagagttgc taattggtta tccaaaaaga caggattgca agttgacatg gtgccaagag
     7321 ttaattcccc tgaacatatc aagactcctg attatttagt tgatgtagct ccttttgatc
     7381 taaaagaaat cacaggttcg ggtaaaaacg tcattgatgg caatctacga aaagcaaaaa
     7441 agcaggcaac taatatcatt tttgatataa caaaaacccc tttatcattt gaagagataa
     7501 tggggcaatt agaacatatt tatatgatag atcgtagggg tcttgatata tcaattatca
     7561 aaaataaaga tgaggtatta gctgtattag aaaaagaagg aggatgaccc accgcctcca
     7621 cagtaaactg cttcatgggc gttagaccat catccttctt tatctcaatt atacatcacc
     7681 ctattaaaac tatcaaggag gaaaatatgt ttatttggca aatggtatta gtggcactag
     7741 gtgtattggt actcatattg attgttggca ttgcagcaat agcggttaag tcaattattg
     7801 cagaattgaa aaaagaagga taaaacaatg aataagcgca ttaagaaaaa acgtaaattg
     7861 gaaacagcgg ttgtgatgct tgttgcagag aatgccatgc aagcagaagc tattaaaaat
     7921 caaaacaaac aaatcatgga gctaaaatca atcgttcaac gaaacgctct ggcaacaaac
     7981 gaagagttag cggctgttaa agctgctact ttagataacc aatcagttat caaggcaatt
     8041 ggtgacacgg ttgactatat taagaaaaac tacaaacgga agtgggggaa ataaagttta
     8101 accgtgtcga atttgacctc tttacaaatc taaaccaaag tcgtagcaat acggcttttt
     8161 attgtgtcca aactttgttg atgacactaa aagctacact gtttcgtcgc aggacgtaaa
     8221 gctagactat cggttggtgg cgtaaccact aggagaaagt tatggcagaa gaaaatgtaa
     8281 caacagagac aactgagcaa gtcgacactc aaaaagaagc tgttgaatat cctaagcatg
     8341 aatatgagcg aacttttact cgcgcagaca tctcaaaaat gatggctgct gaacgcacta
     8401 aatgggaatc tgaacaatcc gcagctattg aaaaagctcg tacagaaggt gaacgtttgg
     8461 ccaagttgtc aaaagatgag cgcgctaaag aggaggaaca aaaacgtcta gatgctatcg
     8521 cagagcgtga aaaagcagta gcagagcgtg agatgcgcat tgagacgcat tccctgcttg
     8581 tggagaaagg attgccattg gattttattg atattgtttt agccactact gcagaagagg
     8641 ttaaggccaa tattgataat ttacaaacta tttttgataa agctgttgaa aaacgtgtta
     8701 acgatcgttt aactcagaaa ccgccacgaa ctggaaatgg ctcggtcggt atgactaagg
     8761 ctgacatcat ggcgatagag gatgacgacg aacgtatgcg tttaattgct gagaatcgta
     8821 acttatttta agaggggaat attatggctg aaaaaaactt aaacactatg gcggacttag
     8881 gagatattaa atcaattgat tttgttaaca agttttccaa aaatattaat gatttattaa
     8941 aattgctagg ggttactcgt cgtgaaacat taactaacga tctaaaaatt cagacctata
     9001 agtgggaagt gactttagat caaactgatc ctggagaagg ggaaacaatc cctctgtcta
     9061 aggttactcg aactaaagat aaagactata cagtgaagtg gttcaagaaa cgtcgtgcaa
     9121 ctacagctga ggcaattgct cgccatggtg cagctcgtgc tattactgaa gcagataagc
     9181 gcattatgcg tgagcttcag aatggaatta aggatgcatt ctttacattc ctcaaaacaa
     9241 aaccaacaaa agttaaaggc gttggccttc aaaaagcgct gtctgcatca tgggctaagc
     9301 tagctacttt taatgagttt gagggttccc cgcttgtttc ttttgtctct cctttagacg
     9361 tagctaacta tcttggagat actaaagtag gtgcggatgc ctctaatgtt tttggaatga
     9421 cattgcttaa gaactttttg ggtatgcaaa atgtgattgt tatgccatct gtgccagagg
     9481 gtaaaatcta ctcaacggct gtagaaaatc tagtttttgc atctttaaat gttaaagggg
     9541 gagacttggg cggcttgttt gctgatttta ctgatgagac aggtttaatt gctgcagctc
     9601 gtaatcgtca gctttctaat cttacctatg aatctgtttt ctttggggcg aatgtactgt
     9661 ttgctgaaat tcctgaaggg gttgtagagg caacaatcga agctgctgct gtacccggca
     9721 ttggtggtta aaggctattt atatgggtga taaacaactt attgacgata tcaaactctt
     9781 tataggtatt tccaagggtg atggtgcgca agatgagctc atcacccttg ctatatatga
     9841 aagtaaagag cgtgtgctag ctaaacttaa tgaatactca gaaactgaaa tcaccaaaat
     9901 tcctgataga ttgaggttta ttgtccgtga tgttgctatt aaacggttta ataggattaa
     9961 ttcagaagga gccgttgaag atagcgaaga aggaaagact tttaagtggg acagttacct
    10021 taaagagtat gaatcaacac tcagaagcgc tgctattggg aaggtatatt caggcaaagg
    10081 ggtagcaaga tttatttagg agatacacaa tgatctataa agatagagta atcttagtgt
    10141 atgtcgatga acaggacgat tttctagata aaagaactgt tgaaaaacct agcgggaaaa
    10201 tcccctgtat ggaaaatact ttcacaaaat ctgaacagat ggggctattt ggtaaatatg
    10261 atttgaatgc ttttaagttg cacttgcaag gccattacga cggctttagc aagattatct
    10321 acaagggaaa atcgaggttg ataaagggac tagcacacca taaaaatagc acggttattt
    10381 atgtatgagt cttatttatc ggatgagagg cctagatagg tttttacgca gcgttgagcg
    10441 caagcagaag tcagtacgaa tcgctgtaga taaagagctt agtaaatcag ctgctaggat
    10501 tgagagacag gctaaaatac tagccccggt tgacactgga tggctgagag ctcaaatcta
    10561 cagtgagcaa caacgactct tacactatag agtggtttct cctgctttat attctattta
    10621 tcttgaatta ggtactcgta aaatggaagc acaatcgttt ttagaccctg ccctgagaaa
    10681 agaatggcct gtgctaatgg ctaatatcaa aaaaatgttt aagaggtgat gcatggatta
    10741 ctcactggaa acactatatt taaaaaaggt aaaaaataga ttgggagttt tagacatacc
    10801 aatctatttt aaattgccta aatcagacgt tttagagcct tttattgttg taggtacaaa
    10861 tatatcagac ttgtcaaaaa cagctcaaac tggagcagtt attgatgatt ttagcctgaa
    10921 tatcgatgct ttcttacctg gcgatagtcg tttggatgca gaagagataa aatctcgcat
    10981 gcttagactg cttgggcgaa ataaccaaat aaaggctcag attttggtag ataattcaat
    11041 aggacgggaa gtctatagag ttgctatcaa cattacagaa acactatttt aaaggggacc
    11101 taaatggcaa acacaaaaaa aggaacaact attgaaatta caacaggtaa accgattgta
    11161 ggaaaaaaga ttttttactt tatacaatca gttgatgcac caaagaaaag tcaggctctg
    11221 ttgccagcct atcgtaccga tggtactaca accatgggtg gtgaatacat tgatgagcaa
    11281 acccaacaag gtcgcgttat tgagaaggct acagatgaac actctattga tttgacaacg
    11341 tactttgtac cgacagatcc atctgttgct gtcatcgagg aagctaagaa aacaggtaaa
    11401 tctatcaaaa tttgggaagt tattgccgac gaaagtgtca aagaacagat tcaaattcct
    11461 gaatcgactg gacccaagaa agatgtttac cctgctaagt ttgggtacgc caagattgac
    11521 gaaatcgaac gcggtactgg tatttcagac ttagtagaaa tgtcctacac cgctaacatt
    11581 gtaggggcct tacaagatgg taaattccct ctcacgaaag aagaaattga aatgctagaa
    11641 aatgtatacg gctatcaaaa tccgggtgat actactggcg actacgataa tatcactaaa
    11701 tagcacacag gggtggcaac tgatacccca ttttgattta aaaaggagat aaaataatgg
    11761 aatttacagc agcaaaacga aatatcgata ttaaatttga ttttaaaact atgtttaaga
    11821 tcaataataa actaggaaca attaacccag aaacaggaga gcgcaatgca gatggtgttg
    11881 gtgctttgtt tttcaatatc ttagagcgta atgaaagcgc cattgttgac cttgtgcgtt
    11941 tatctgcggg aagcggaaaa aaagcgctaa ctgaagatga aattctagat gcaattgcag
    12001 aatctgttga tgaagaagga acaacagaag ggttgtttgc tgagattgaa aaagaaatgg
    12061 ttgattctgg ttttttcaga gcgaagattt tgaaatatat cgaaaacatg gagaaatcag
    12121 ctcgttatct caaagcgaag gacgatatgg acgcaactca aatccaaatt attgaagaca
    12181 tgattggaag aatgagcaac gcagtatctt agtaaattgc gcacggctag ggctcacaga
    12241 cattgatact atctataaat gtactaagtg ggagctagag gctattatgg aggggcttga
    12301 gtataagcag cttgctgagc gcgagagcct ctctgaattg tctctaaagc ttagatatac
    12361 attaaatgct aaaaaggttg atgtaggtaa gctcaaatac gataagcata ggctaactat
    12421 caaaagatcg tatcaaaaag ctagccgtag ccaagccgat agtgatagca gtattgttga
    12481 gagaatacaa atgcttaata atcattttca aaatagatag ataaggagga gtagatgcca
    12541 ggaacatttg atggttctat tttcgctgat gttggtgcca acacaaagga ctatgagcaa
    12601 gccatggctc gtattgttag tacgactcag aatgctttca gaaaagccca agatacagcg
    12661 gttaacagta gtaataaaat ggttcaaatc attggacaaa tcatggccca actggcgaac
    12721 aacggcgaat cgctcgggaa gagacttggc tctgcctacg ctactggttt aaaactgagc
    12781 atcggtgaaa ttcaacgcat agcagcttcc attggcgaaa aaattcccga acccataaag
    12841 aatggttttc aaaaaatcat tattccagtt gcaagtgtta ctgacaaaat acggggtaac
    12901 ttaaccggtt tcattaatca aacaaaaatg caacttcaga atcttgtggg tattggcaag
    12961 ataagatctg catttgccaa ggctgcgact ggagttgata tcttaactca gagggcaagt
    13021 agtaagctta ataacttatc tgcaatattc gaaacggtcg caggcaagct tccgcgacca
    13081 ttcggaacag cgtttagaaa aattgcctca tccgtttcta ccctgaatag ctctatacag
    13141 tctgttggag ggaagatttc taattcactt ggtcagcaag tcttgaaccc agccttacag
    13201 tcatggaata atttttttag ttctgtatca gctaaggcgt ctgctttcgc aaacaaagtg
    13261 agtactagtt tgtttggtcg gctgacctca agtttagcta atttatcaag taaaataggg
    13321 agcagtctta gcaatggttt tagcagaatg tctagttctg cggctacttc cttgaatgga
    13381 ataagccaga aattcgccaa tacctcttct gctggagaga gactcaaaag tacagtgatg
    13441 agcatcgtgc aggcctttag tttaatggct gttgctcaaa aagctatgca cgctattact
    13501 ggggcaatag acggggcggt tagtcgcgtt gataccatga accgctttcc gaaaacgatg
    13561 gcgctatttg ggtattctgc tgaacaatct aaggcatcaa ttgataagct atcaaaagga
    13621 attgaaggtc tgccaactcc tctagacagt gctgtaaaaa gcgctcaaca gctcgccata
    13681 accacaggaa gtttagataa agggactagt ttagccctcg ccttcaataa cgcaatgatc
    13741 ggttacgggg caacaactga aggggctgag caagcactca ggcagtttag ccagtcgttg
    13801 gggtctggaa aaattcaagc tgaagagttt aactctgtat cagaagctgc gccaggttta
    13861 atgtctaaaa tggcggaagc cttcggtttt ggtaaaaatg gcgtacaaga tttaaaatca
    13921 gccttatctg atggcaaaat cactgcacaa gagttcgcag ataaaatgat tgagcttaac
    13981 gatgcccaag gcggatttgc agagatggcc caatcatcgg ctggtggaat ccgaactgca
    14041 tggaagaacg tacataccgc cgtcgtaaaa ggcgtagcag gtatgatttc agcctttgat
    14101 gaagcggcta aagctaatgg catgaagacc attgctgaaa cacttcttag tctgaagcca
    14161 gcaataacca gtgtttttga tacgattaat tctcttattc caaatgcagt tgcagcattc
    14221 gctaggctaa aacagtctat caatattgac tttagcccat taggcgccag cgttaaagag
    14281 gtgtttgctc ttattaatac tgttcttaga gattttgcac atactggtga attatcaggg
    14341 caggcttttg ataatctaaa agcaaaaatc acttctttag cccctaaagt cattgccctt
    14401 tgggcagtga tgaaccccgc tagcgctata tcaacgataa tgcctttgct ttctctattc
    14461 ggaaaagttg ctctagcttt aggaagctta gggacttctg tcggggcgtt tggcggcata
    14521 atttctagtg ggatagctag tgccagcggc gttgttggtg cctttgcggc aactctaagc
    14581 ggattacctg gcgtttttgc taccgcagca gggcgtgggc tatctgtgct tggaactatg
    14641 acaagcgcaa tgtccagtct tgtgagttta gcactggcgg ccataggacc ggccgctatt
    14701 ctaggtcttg tggtggcagg acttggtttg attaatagtc agtttggcgc acaaatcgag
    14761 cagctactta acaccgcagt tacaaaaggt cctggtatta ttcaaggcct tgtaaaagga
    14821 attacttcta aaataccagt tttgatagct agtggcactc aattgattgc taaatttgca
    14881 aatgctatca cagtgttatt accagttata attcaagctg gcgttcagct aattacgagt
    14941 ctcgtccaag gtattggaca aaatgcaacg aatttaatta gttcagcaat aaaaatcatt
    15001 ggtagttttg ttagttcaat tgcgagtgca ttgccgcagc ttatttctgt tggaatggag
    15061 ctattattaa atgttgtcaa cggcatagtt caaaatatac ctcttattat ccagcaagcc
    15121 cagcaaatta ttgatagttt tgggaatagt ttacaggcta accttcctag tattattagc
    15181 aacggtatag ctattttggt gaatcttgta cagggaatta ctcaaatgtt gccaactgtt
    15241 ctgcagatag ctactcaagt cattacgagt tttgtatctg gaattgtaca gtttttaccg
    15301 cagttacttc aaggtggcat tcaaatcatt attagccttg tgcaggggat tattcaaaat
    15361 ctaccccaga ttgcacaatc tgctgtacag attatacagt ttttagcttc tggactgacg
    15421 caagctctac ctcagattat cgcagcaggc attcagcttg ttgcgcaact agccgtagcc
    15481 ttgataaagg gacttccaca gattatttct gcgggtattc aattaattat ggggctcggt
    15541 aaagccatgt taggggctat cccaaacgct ctttcaggag tttgggaagg tattaagagc
    15601 ggattcagtt cgatgtggga ccaaatcaca ggtaagagtt ccacaagtac agctaaagtc
    15661 tctgcggacg ccacggtcat ggccatgaat gttgggatgc aaacgacagc tatagctaat
    15721 caagctaata cagatacgac atctatgctt aatagcatta gtcaaaatac agagcttgct
    15781 aatataaacg ctacatcaaa tgccacacag atggctaata acgttaatgc tcagacagga
    15841 acgatgagtc ttcgggggtt gaatgattcg atgtctcttg cgagtggcat tagcgctaat
    15901 atgtctgtcg ctaatataaa cgctactact caggctcgag aaatggcttc aggggttaat
    15961 ggtgcgactt cttcaatgaa tctagacgcc attaatcata cgctcagctt agctagtggt
    16021 gttggtgcga acatgggagc tgctagcaca ggtgcaactt ctcaggcgca agctatgagc
    16081 tcaggggtga gtaacagcct ggcatcaatg cagtcaaact caactaaagc agcctctggt
    16141 ctgtctaata gtgtgacaag cgaaatgtct tctgcagcaa cctctgcaac ctcaagcgtt
    16201 aataggttgt cctcggcggt cgagtctggc ttcaataagg cgaagacttc agcaacaacc
    16261 tcaatgaatg ggatagccaa tgcggttaaa acaggattta gtagcattaa cagtactgca
    16321 aagcaatcta tggcaaacct tgtaagttca gtgacttctg ggatgtctcg tgcaaccgcg
    16381 gtgtctaata atgcttgtca gaagatcctc tcaatattca gggctttggc agggcagatg
    16441 tcttctgcag gagcttatgc aggtcaaggt tttgctaatg gtctagctag tagcgcaggc
    16501 acaatctacg caatagctaa cagcattgcc gctaatgtag cagcaacaat tagacgcgct
    16561 ttagatattc actcaccatc tcgtgtcact aaaacactag gtgcatttac tggagagggg
    16621 tttgccctcg gtatggcaga gtggataggt gagatcaata gcctaggtaa agcatacgca
    16681 acagcagtta ctgatcaaaa ctggggggta aatagtactg tttcaacatc tgctaaagtt
    16741 aataatagtg gaatcaatac ctctcttgat aatcttagcg aagaggttag gcagtctcaa
    16801 ttgtcagagc ctatctttga agtgcataat gagattgttg gagataaaat ttacacggct
    16861 gttaaagaaa aagaatcaag agagcaatct aaagattctt attttgtttt tgactagaag
    16921 ggagtatttt ggatttatta atagaaaaag agagtcaggc aactaggttg tctgactttg
    16981 gtatttataa tattgctatt gaagatagcg ctcctttact atctgtatca caccgagcag
    17041 tcaaaggaag gagtggttac atctacgatg gggctacttt tacgactaaa acgcttaagg
    17101 tcaaaggaag agtgacgata agcaacgtag aaagactttt ggacaaacag gacgaactaa
    17161 acgctctgct tgttgttgac gaacctttct acgtgactaa gatgtaccct gaaaactcag
    17221 atctatttaa ctttgagctt ccaggggaaa gcacaggaga cctgcaactt attggctctc
    17281 ctcataaacc ttggaaatat agatttaaag tcatcttaga cgacactatc gcttatgaat
    17341 ttataggaaa aaccagtcaa ggactaaaat ataatctttc cttcgcgcta agaactgctg
    17401 aattaccttt cggtgagaca aagccaaagg acataactct atcagggggc agttttgcct
    17461 atgcaggaac cgctaaagca agtcagctag agtggccttt tattatagag cttactcctt
    17521 ctggaggtca gactaatttt tatattgaaa ttgatggcag gcgctttgag tttaagcaga
    17581 atagccagct acaaaatagt gataaattac ttttgacagg catagctacc acgctaaacg
    17641 gaaattatgt caatgctaaa acgaactatg agtattttat cttcaatcct aatcctaaca
    17701 agagaattac ttacaaaacg gattttcttg gcacgattag gattttaaat tttgtagagt
    17761 tgtataaata gggaggtcta atgattactt ttttggatca tcgtgacatt gagtatgggg
    17821 tcattagtgt cattaggcat actaatgctg ttaatggtga gcgctcagtg agcggggaaa
    17881 tttatacaaa cagtgatgtc ctcaataata tcgatagagg gtggcgactt agatttgaag
    17941 atgagtatta cgttgttatt tacgcaaagc ctgttgatgt tggtcaaaaa acgcaagttt
    18001 cgtttgatgc catacaccaa tttttttggg acttcagcaa gagtagtatc tatgagggtc
    18061 tcggagatgg gtctcatacc attgatacct atctagagac agtatttaaa ggtagtgggt
    18121 accgctataa gctagaagta ggtgtgaacg catttagaaa acaatctttt aattataagt
    18181 ccaggttaga tttattcaat gagattatta aagcgaccgg acttgaattt tcagtcagcg
    18241 ggaaagttgt tcggctacta aaaaacatag gtactgatct gtcaacagtg gtacgaaaaa
    18301 atttcaacat gaatgacctt accattgaaa aaaatattga tagctttatt acctatcaga
    18361 aaggctttgg tgcatggacc gacccagagg accactctaa ggggagactt gaggcggaat
    18421 acgaaagtcc tcttgccaag gagtacggtc gacttgaagg ggcgcctctg acggatgagc
    18481 gcttcacggt ggcagataat ctaaaagaag ctttaaaaag taatgttgaa aattcatata
    18541 agatatcagt aaaaattgat atggaagatt taacgagagc tgggtataga tgtgagaggc
    18601 cggttgctgg tgactacatt atggcgataa atgagacttt aggttttcaa gagcgtatac
    18661 ggatagtttc ttttacaagc tactacgacg caactggagc tttagtaaaa catgaagtca
    18721 cttgtaatga tatcggatct gtgaaaaaac aaagcgtagg aagtctgtct ataaacagta
    18781 gaatcaatca gatagatgca gatattgctt ctgcaattga agtagcaaca caagcactag
    18841 tatctgctga cgggaaaaat actgtttacg gtggcacaga aatgcccaaa gatgaaccaa
    18901 aaggaacctt aaaaaaagga gacatattat tcctaaaagt tggcgatact actagaatgt
    18961 atttctggaa tggtgctgag tgggaagaac ctgaggttgt gaacgaccca gaacgatggc
    19021 gtgaagacct cgaaaaacaa atctctgagg cgatcgaaaa agccaaaaaa gcacaggaag
    19081 aaatcaacca acgcaccgat aaagagcttg aagaatttag agccgccctc aaaaacctag
    19141 cgttaccaga ggaagcgatt aaaaaaatca ccgaggctat aaaagttgat gacatcccgt
    19201 ctattaaaca aagctttgat gacctcaaaa atagagtgag tgagacaagc gaagaatctc
    19261 gtttaactgc cgaaatttta ggaaataacg gtaagacccg ctataacaaa aatttattgg
    19321 ttggcgaccc taaccgtgta aaaacctatg accaagacta tatcgaggta gaagctaatg
    19381 atggcggctt taagcgtggc gagacctaca cgattagctt tagtcaaacg tgtgagctac
    19441 tcaaagaagt agctatcaca ttgacgcaaa ttaacaacaa gggagttaag ttagtactga
    19501 caccaaccaa agcaaaaatg gatgcacaga cgtttgaggt cactaaggat aaacagtcta
    19561 tagaggtata tcctttaagt tatacaggcg ttttaactgg tgactggtat aaacctaagc
    19621 aaatagattt aaacgcctca gacacgcagg aattggctct agagatggat tataaagatg
    19681 ttgttgacgg caaggatgcc acaataacag gggcatggtc agacagtcca caaataattt
    19741 tatacggagg taaaaaatga cagaaactat accattaaga gtccaattta agcggatgaa
    19801 agccgccgag tgggcaagta gtgatgtcgt cttactggag ggtgagattg gctttgagac
    19861 tgacactggt tttgctaagt ttggcgatgg tcaaaacact tttagtaagc ttaagtacct
    19921 tactggtccc aaaggtccta aaggagacac tggtctccaa ggtaaaactg gaggaactgg
    19981 tcctcggggc cctgctggca agcctggaac gacagattat gatcaactcc aaaataaacc
    20041 agatctaggt gcgtttgcac aaaaagaaga aactaatagt aaaatcacca aattagaatc
    20101 aagcaaagca gataaaaacg ctgtttactt aaaagcagag tcaaaaatag agcttgacaa
    20161 gaaattaaat ctcaaaggcg gcgtcatgac aggtcaacta cagtttaaac ctaataaaag
    20221 tggtattaaa ccctcatctt ccgtaggagg agcgattaac attgatatgt ctaaatcgga
    20281 aggtgctggt gttgttgtct attctaacaa tgataccagt gatgggccgt taatgagctt
    20341 gcggacgggt aaagagacct tcaatcaatc agcgcttttt gtcgattaca gcggtaagac
    20401 taatgccgtt aatattgcga tgcgtcagcc aaccaccccc aatttttcct ctgcgcttaa
    20461 tattactagc ggcaatgaaa atggtagtgc gatgcaaatt agaggcgtcg aaaaagcatt
    20521 gggaacgctc aaaatcacac acgaaaaccc aagcgttgag gcaaattacg atgaaaacgc
    20581 tgcagcgtta tctattgata tcgttaaaaa acagaaaggc ggaaaaggta ctgctgctca
    20641 aggaatctac attaactcaa cctcaggaac gacagggaag ttgcttagga ttagaaatct
    20701 tggtgatgat aagttctacg tcaagtctga cggtggtttt tatgccaaga aaacttcgca
    20761 gattgatggc aacctgaaac tcaaggaccc cacagcgaat gatcatgcgg caaccaaagc
    20821 ttatgtagat aaagcaattt ctgagttaaa aaaactcata ctaaaaaaat agattaagga
    20881 ggataaatga gcagagaccc aacacttatt ttagacgagt caaacctcgt tattggtaag
    20941 gatggacgtg tgcattacac atttaccgca gaggacgaca acccaaaagt cagactagct
    21001 agcaagtgtc taggcacagc gcattttaat cagctcatga ttgagcgagg agaccaagct
    21061 actagctatg tagcaccagt agtagttgag ggtacaggta atccgactgg actatttaaa
    21121 gacctcaagg agattagtct agagctgaca gacatcgaaa attccaagtt atggtcaaaa
    21181 atcaaggtaa acaaccgagg tatgttgcag gagtactacg acggcacgat taagactgag
    21241 attatcaact ccgcacaagg tgtggctaca cgcatcagtg aggacactgg caaaaagcta
    21301 gcacttatca atgacactat caacggtata aggcgagagt atcaaaacgc tgataaaaag
    21361 ctatcagcta gctatcaagc tggcatagac ggcttaaaaa ccacaatggc caatgataaa
    21421 atcggtttac aagctgagat taaagcctca gcacaagggc tatcgcaaaa gtatgatgat
    21481 gagttgcgca agttatctgc taagatcaca acaacctcaa gcggcacgac cgaggcctac
    21541 gaaaacaaac tcaatggctt acgtgctgag tttactcgct caaatcaagg tatgcggaca
    21601 gaactcgagt ctaaaatcag cggactaaga acggcgcaac agaccactgc taaccaaatc
    21661 tcacaagaga tacgtaaccg cgaaggtgct gtcagccgtg tgcaacagga cttagctagc
    21721 tatcagcggc gattgcagga cgcagaggat aattacagta gcttaaccca tacaattaga
    21781 ggtttgcaga gtgatgtggg gtccccgact ggtaaaatcc aatcacgcct tactcaacta
    21841 gcaggacaaa ttgagcagcg ggttactaga gatggtgtca tgagtattat tagtggcgct
    21901 ggagacagca ttaaattagc tatccaaaag gctggcggca ttaatgccaa aatgtctggt
    21961 aatgagatta tctcagcaat taacctcaac tcctacggag taacaatcgc aggtaaacat
    22021 atcgctctcg atggcaatac gactgtcaac ggtaccttta ccacaaagat agcagaggct
    22081 atcaagatta gggctgatca gattattgca ggcacgattg acgctgctag gattagagtg
    22141 attaacctta acgcaagtag tatcgttggt ttagacgcta actttatcaa agctaaaatt
    22201 ggctatgcta tcactgattt gctcgagggt aaggtcatta aggctcgtaa tggagcgatg
    22261 cttatcgact taaatacagc taagatggac tttaatagcg atgccacaat taattttaat
    22321 agcaaaaaca atgccttagt acgtaaagat ggcacacata ctgcctttgt acattttagt
    22381 aatgcgacgc caaaaggcta tagaggctca gcgttgtatg cctctatcgg cattacctca
    22441 tcaggagatg gcatcgacag cgcttcgtct ggacgtttct gtggagttag gtttttccgg
    22501 tacgc
//
LOCUS       DAUCXI010000030        22225 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.030, whole genome shotgun sequence.
ACCESSION   DAUCXI010000030 DAUCXI010000000
VERSION     DAUCXI010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22225
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.030"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            47..784
                     /gene="erm(B)"
                     /locus_tag="VGY43_001244"
     CDS             47..784
                     /gene="erm(B)"
                     /locus_tag="VGY43_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEQ4302426.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1139..1693
                     /locus_tag="VGY43_001245"
     CDS             1139..1693
                     /locus_tag="VGY43_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002402802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEQ4302427.1"
                     /translation="MIFGYARVSTDDQNLSLQIDALTHYGIDKLFQEKVTGAKKDRPQ
                     LEEMINLLREGDSVVIYKLDRISRSTKHLIELSELFEELSVNFISIQDNVDTSTSMGR
                     FFFRVMASLAELERDIIIERTNSGLKAARVRGKKGGRPSKGKLSIDLALKMYDSKEYS
                     IRQILDASKLSKTTFYRYLNKRNA"
     gene            1697..4615
                     /locus_tag="VGY43_001246"
     CDS             1697..4615
                     /locus_tag="VGY43_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HEQ4302428.1"
                     /translation="MAMKRILTTSQREQLLSVDHLSEEDFKAYFSFSDYDLEVINQHR
                     GKVNKLGFAIQLCLARYPGCSLSNWPIKSTRLTSYVSRQLHLDAIDLNSYDHRNTRAN
                     HFNEILEVFNYHRFGSANTQKQLIEYLIELALENDDSIYLMKKTIDFLTRKRIIFPSI
                     ATLEDIISRCRDKAENNLFSILLCSLTDIQIEKLESLFQIYEETKITKLAWLKDIPGK
                     ANPESFMSICKKVEVIASMGLGTINVSHINRNRFLQLARLGENYDAYDFSRFELEKRY
                     SLLIAFLVNHHQYLIDQLIEINDRILASIKRKGTRDSQEQLKEKGKLATKKLEHYASL
                     IDALHFAKDNDSNPFDEIERIMPWEDLVQDGEEAKKITGNKNHGYLEMVRNKANYLRR
                     YTPMLLRTLSFKATPAANPVLMALTQLTDLHNSGKRKIPADTSTDFVSKKWKSLVRPE
                     EGKIDRSYYELVAFTELKNNIRSGDISVEGSMIHRNIDDYLVDLSACIDSETIPDTFE
                     DYLKDREIILDLQLQFYSTVDKRISRANLKKLEKVTPSEAEIYRKKLYSIIPKIRLSD
                     LLIEVDSWTNFSQEFSHDSTGKPPSEQERKIIFAALLGLGMNIGLEKMAQSTPGISYS
                     QLANAKQWRFYKEALTRAQSVLVNYQLKLPVADFWGEGKTTASDGMRVPVGVSALKSD
                     VNPHYKSMEKGATMIRSINDRHTTHHIEVASTNTREATHTLDGLLYHETDLDIEEHFT
                     DTNGYSDQVFGMTALLGFDFEPRIRNIKKSQLFSIKSPSYYPNLSEDISGKINVKIIE
                     ENYDEIKRIAYSIQTGKVSSSLLLGKLGSYARKNRVALALRELGRIEKSIFMIDYITD
                     SELRRRITHGLNKTEAINALARELFFGRRGKFMERDIRRQLQSASALNVLINAISIWN
                     AVYLQAAYNYLVKIDPEVTKYMKHVSPINWEHITFLGEYKFDLLSIPKHLRELNIKNK
                     "
     gene            complement(4689..4910)
                     /locus_tag="VGY43_001247"
                     /pseudo
     CDS             complement(4689..4910)
                     /locus_tag="VGY43_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            5415..5837
                     /locus_tag="VGY43_001248"
     CDS             5415..5837
                     /locus_tag="VGY43_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEQ4302429.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            5834..6064
                     /locus_tag="VGY43_001249"
     CDS             5834..6064
                     /locus_tag="VGY43_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ4302430.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            6525..6728
                     /locus_tag="VGY43_001250"
     CDS             6525..6728
                     /locus_tag="VGY43_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEQ4302431.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            6810..8027
                     /locus_tag="VGY43_001251"
     CDS             6810..8027
                     /locus_tag="VGY43_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEQ4302432.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(8432..11245)
                     /locus_tag="VGY43_001252"
     CDS             complement(8432..11245)
                     /locus_tag="VGY43_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ4302433.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKNEIKQKLEEMREASKARVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFKEAKVEAKEERKESRKERKTNQKFLYGQESKAKSNFFFQGKSLEEFKSKKE
                     VKAAKENLKSTKQAYKFKKISRKAKTFLYVLGREGGELASENEDLESYRTLHETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKENPSSFKNR
                     FRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPVTWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKIDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSRDDQEEIKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDGVVSL
                     DGDNVILTNGNGENESRLTLYSIHNGRAIEGTRVLTGDIIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATDSSWDDESWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHTQNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFGNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGRNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPASYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(11257..13614)
                     /locus_tag="VGY43_001253"
     CDS             complement(11257..13614)
                     /locus_tag="VGY43_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ4302434.1"
                     /translation="MKRKSNTLKKQKTSMTNQKEVVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDSYRQELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEERVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGVFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSEENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            complement(13565..13924)
                     /locus_tag="VGY43_001254"
     CDS             complement(13565..13924)
                     /locus_tag="VGY43_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEQ4302435.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGS
                     EHEKKIKYIKETKNFND"
     gene            complement(13978..14832)
                     /locus_tag="VGY43_001255"
     CDS             complement(13978..14832)
                     /locus_tag="VGY43_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HEQ4302436.1"
                     /translation="MNLSLVSPFIYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLIQAILLIIALVGSQR
                     TARSILGM"
     gene            complement(14849..15091)
                     /locus_tag="VGY43_001256"
     CDS             complement(14849..15091)
                     /locus_tag="VGY43_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302437.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            complement(15112..16989)
                     /locus_tag="VGY43_001257"
     CDS             complement(15112..16989)
                     /locus_tag="VGY43_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HEQ4302438.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFIEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQT
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGQEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSIKHPNWKYLANQESDERWWNYQINPLNQRQENHLEGLRIRDLTFESSL
                     K"
     gene            complement(16989..17477)
                     /locus_tag="VGY43_001258"
     CDS             complement(16989..17477)
                     /locus_tag="VGY43_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302439.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALSQDSAYK
                     IGVQKLEELLQSPYSIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     TKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            complement(17467..17766)
                     /locus_tag="VGY43_001259"
     CDS             complement(17467..17766)
                     /locus_tag="VGY43_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302440.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIIDGKAVEVTLREPYSRDLLQVVKSIKQRQKLIAYRYKEGKLLFVKKEASDVL"
     gene            complement(18080..18667)
                     /locus_tag="VGY43_001260"
     CDS             complement(18080..18667)
                     /locus_tag="VGY43_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ4302441.1"
                     /translation="MKRIIPVYIFQQVNILLVSLYLLKFLCSGELTILQILYCGSLIS
                     FLWMYGQRKQAHKIDMKTRMKWLGVGFVSLLIISLCFSLIHAQGSTNQANLIGIQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMELHLVWNLLVYSLLLV"
     gene            complement(18670..18903)
                     /locus_tag="VGY43_001261"
     CDS             complement(18670..18903)
                     /locus_tag="VGY43_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEQ4302442.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKVEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(18916..19296)
                     /locus_tag="VGY43_001262"
     CDS             complement(18916..19296)
                     /locus_tag="VGY43_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302443.1"
                     /translation="MIDLYLSKNSHRNQLLLEFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(19289..19738)
                     /locus_tag="VGY43_001263"
     CDS             complement(19289..19738)
                     /locus_tag="VGY43_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302444.1"
                     /translation="MKALNKESILDCDELETELHDAEMMQLDEQIFLMPNYPCEFEVK
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNLVFILYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSHSLDSLIVSEYQIEANQWEVSHD"
     gene            complement(19722..21080)
                     /gene="dcm"
                     /locus_tag="VGY43_001264"
     CDS             complement(19722..21080)
                     /gene="dcm"
                     /locus_tag="VGY43_001264"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HEQ4302445.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKRGTRLLFPFRREGQATNSETLKILGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLKKRQNGRRFKDNQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGVLIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDES
                     VK"
     gene            complement(21179..21958)
                     /locus_tag="VGY43_001265"
     CDS             complement(21179..21958)
                     /locus_tag="VGY43_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEQ4302446.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSNLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVASSNRPSVKKRLCQDENEAAPVSYSAPSETEVSETKYSE
                     TESLFIEDEEERNSQPILRRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(21955..22128)
                     /locus_tag="VGY43_001266"
     CDS             complement(21955..22128)
                     /locus_tag="VGY43_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302447.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGNLILKELGGAL"
BASE COUNT         7064 a         4342 c         3783 g         7036 t
ORIGIN      
        1 aacttctgta tttatttata gatctaatca cttcaggagt gattacatga acaaaaatat
       61 aaaatattct caaaactttt taacgagtga aaaagtactc aaccaaataa taaaacaatt
      121 gaatttaaaa gaaaccgata ccgtttacga aattggaaca ggtaaagggc atttaacgac
      181 gaaactggct aaaataagta aacaggtaac gtctattgaa ttagacagtc atctattcaa
      241 cttatcgtca gaaaaattaa aactgaacat tcgtgtcact ttaattcacc aagatattct
      301 acagtttcaa ttccctaaca aacagaggta taaaattgtt gggaatattc cttaccattt
      361 aagcacacaa attattaaaa aagtggtttt tgaaagccat gcgtctgaca tctatctgat
      421 tgttgaagaa ggattctaca agcgtacctt ggatattcac cgaacactag ggttgctctt
      481 gcacactcaa gtctcgattc agcaattgct taagctgcca gcggaatgct ttcatcctaa
      541 accaaaagta aacagtgtct taataaaact tacccgccat accacagatg ttccagataa
      601 atattggaag ctatatacgt actttgtttc aaaatgggtc aatcgagaat atcgtcaact
      661 gtttactaaa aatcagtttc atcaagcaat gaaacacgcc aaagtaaaca atttaagtac
      721 cgttacttat gagcaagtat tgtctatttt taatagttat ctattattta acgggaggaa
      781 ataattctat gagtcgcttt tgtaaatttg gaaagttaca cgttactaaa gggaatgtag
      841 ataaattatt aggtatacta ctgacagctt ccaaggagct aaagaggtcc ctagcgccta
      901 cggggaattt gtatcgataa ggaatagatt taaaaatttc gctgttattt tgtacaataa
      961 ggataaattt gaatggtacc ataaacgacc gtttatggta ccttttcatt ttcctgcttt
     1021 ttctaaatgt tttttaagta aatcaagtac caaaatccgt tcctttttca tagttcctat
     1081 atagttatac ttaatgagtt atggtacatt taaattataa aattaaggag gtttttttat
     1141 gatttttggc tatgctcgag tgagtacgga tgatcaaaat cttagtttac aaattgatgc
     1201 acttactcat tatggaattg ataaattatt tcaagaaaaa gtaactggtg cgaaaaaaga
     1261 ccgaccgcaa ttagaagaaa tgatcaacct actacgtgaa ggagattctg ttgtcattta
     1321 caagttagat cgaatttcac gatcaactaa acatttgatt gaactttctg aattatttga
     1381 agaacttagt gtcaatttta tatctattca agataacgta gatacttcaa cgtctatggg
     1441 aagattcttt ttccgagtta tggctagttt agcagaactg gaacgggata ttattattga
     1501 acgaactaac tctggtctta aggcagccag agtccgagga aaaaaagggg gccgtccaag
     1561 taaaggtaag ctatcaattg atttagcttt aaaaatgtat gacagcaaag agtattctat
     1621 tcgtcaaatt cttgatgcct ctaaattaag caaaacaacc ttttaccgtt acctcaataa
     1681 aaggaatgct taagatatgg ctatgaaaag aattttaact acttcacagc gtgaacaact
     1741 tctttctgta gaccacttat cagaagagga ttttaaagcg tattttagtt tttctgatta
     1801 tgatctggag gttattaatc aacaccgtgg aaaggtcaat aaactaggat ttgcgataca
     1861 actttgtttg gcccggtatc ctgggtgttc tttaagtaat tggccgatta aatcaaccag
     1921 actaacttct tatgtgagtc gacagctcca tcttgatgca attgatttaa attcatatga
     1981 tcatagaaat acacgtgcaa atcacttcaa cgagatctta gaagtattca actatcatcg
     2041 attcggtagt gctaatacac aaaaacagtt aatagaatat ttaattgaac tagctttaga
     2101 aaatgatgac tctatctatc taatgaaaaa aacaattgat ttcttaactc gaaaaagaat
     2161 tatttttcca tctatagcta cacttgaaga cattataagc cgctgtcgag ataaagcaga
     2221 aaacaactta ttttcaatat tactctgttc attaacagat atacaaattg aaaaactaga
     2281 gagtttgttt caaatttatg aagagacgaa aataactaaa ctcgcttggc taaaagacat
     2341 tccaggtaag gcaaatccag aaagctttat gagtatttgt aaaaaagtgg aagtgattgc
     2401 ttccatggga ctcgggacaa ttaatgtctc ccatattaat cggaacaggt ttcttcagct
     2461 agctagacta ggggaaaatt atgatgcata tgacttctcc cgttttgagc ttgaaaaaag
     2521 atactcttta cttattgctt ttttagtcaa tcatcatcaa tatctgatcg atcaactgat
     2581 tgagattaat gaccgcattt tagcaagtat taaacgcaaa gggacacgtg attcacaaga
     2641 acagttaaaa gaaaaaggaa aattggctac taaaaaattg gaacattatg cttctttaat
     2701 tgatgctctt cactttgcaa aagataatga tagtaatcct tttgacgaaa ttgaacgaat
     2761 catgccttgg gaagatttag tacaagatgg agaagaagct aaaaaaatta caggtaataa
     2821 aaatcatggc tatttagaaa tggttcgaaa taaagctaat tacctccgaa gatacacgcc
     2881 aatgttattg aggacccttt cgttcaaagc aactccggca gcaaatccag tcctcatggc
     2941 cctaactcaa ctaactgatt tacacaatag tggtaaaaga aaaataccgg cagatacttc
     3001 tactgatttt gtgagtaaaa aatggaaaag ccttgttcgg ccagaagagg ggaaaataga
     3061 tcggtcttac tatgagttag tagctttcac cgagctaaag aacaatattc gatcaggaga
     3121 tatttcagtt gaaggaagta tgatccatcg aaatattgat gattacttag ttgatttatc
     3181 tgcttgtatt gattcagaaa ctattccaga cacgtttgag gactatttaa aggatcggga
     3241 aataatttta gatttacagc ttcaatttta ttcgacagtt gataagagaa tttcaagagc
     3301 aaaccttaaa aagttggaaa aagttacacc tagcgaagca gaaatatata gaaaaaaact
     3361 ttattcaata attcctaaga taaggcttag tgatctttta attgaggtgg acagttggac
     3421 caacttttca caagaattta gtcatgattc tacagggaaa ccgccgagtg aacaagaaag
     3481 aaaaattatt tttgctgctt tgctgggttt agggatgaat attggtcttg aaaaaatggc
     3541 ccaatcaact cctggaattt cttattctca gttagccaat gccaaacaat ggcgctttta
     3601 taaagaagct ctgactcgtg ctcaatctgt tttggttaat tatcagttaa agcttcctgt
     3661 tgcagacttt tggggtgaag gaaaaaccac tgcttcagac ggaatgcgcg tcccagtggg
     3721 cgtctcagct ctaaaatccg atgttaatcc acattacaaa agtatggaaa aaggagctac
     3781 aatgattcga tcaataaatg ataggcatac gactcatcat atcgaggttg cttcaactaa
     3841 tacaagggaa gctactcata cccttgatgg cctactttat catgaaacag atctagatat
     3901 tgaggaacat tttactgata caaatgggta ttctgatcag gtgtttggaa tgaccgcatt
     3961 actaggcttt gattttgaac ctcgcatcag aaatataaaa aaatcacaat tattttctat
     4021 caaatcacct tcctactacc ctaacttatc agaagatata agcggaaaaa tcaatgtaaa
     4081 aattattgaa gaaaactatg atgaaattaa acgaatcgcc tattcgattc aaacaggaaa
     4141 agtatctagt tctttactat taggaaagct aggctcatac gcacgtaaga atagagtagc
     4201 tcttgcactg agagaactag gtcgcattga aaagagcatt tttatgatag attatattac
     4261 agatagtgag ctacggcgaa ggatcactca tggactaaat aagacagaag cgattaatgc
     4321 tttagctaga gaactatttt ttgggcgacg cggaaaattt atggagcgcg atattcgccg
     4381 acaacttcaa agtgctagtg cgcttaatgt gttaataaat gcaataagta tatggaacgc
     4441 cgtctactta caagcagctt ataattatct cgtcaaaata gatcccgaag taactaagta
     4501 tatgaagcat gtatctccta ttaattggga gcatatcact tttcttggag agtataaatt
     4561 tgacttgtta tctattccta aacacttaag agaattgaat ataaaaaata aataggcctt
     4621 gaaacattgg tttagtggga atttgtaccc cttatcgata caaattccca ctaagcgctc
     4681 gggaccccag gtaagaaaaa ttcatcaacg gaaacatgaa gtaacgatac aaggtcataa
     4741 agaacttgta tgctggggtg ttgcccttta ttttcaatat tagttaagta ccgtgggtca
     4801 atttcaatca atgctcccac ttgttcacga gttaaacctc gtttcaatcg agcttcttta
     4861 atggctaaac caaaggctct aaaatcatat ttatcttctt ttttacgcat agtagaccac
     4921 ctctatacat tttattgttc ctactgaatt aaaaacaggt atagaaaaac gtgttatatg
     4981 gtttataggt ttatatttaa taaaaagcac tactaaacgc caataaaaaa aaccgttata
     5041 tggtagtgct atttacgctg ttaaaatatt gtatattact tccaaatggc ggtttgttgg
     5101 aggtcaacgt cgccatgaag tacatcatat acaataaatt tccttacatt gggttcttgt
     5161 caaaaaaagt cgtctatctg caatagataa gtacgtccac caatgtggtt ttataaatca
     5221 tatagataga ataacagaag catgtaaaca gagaaataaa tctgtttata tgcttttttg
     5281 gctattcaga acttttttac aaagtttatt tatcagtaat gcaacaaatc cccctttcac
     5341 attgggacta agagtgaaag gagataaacg agcaaggctc acttcctttc ctagacagaa
     5401 agggggtgag aaacatgaaa ccatcttctt ttcagaccac aatagaaaat cagtttgact
     5461 atatctgtaa acgtgctatg gaagacgagc gaaagaatta tatgctttat ctttcaagga
     5521 ttgcaaagcg tgaggtgtcc ttttcggatg ttggcgatta tcttgttagc cagtttgcga
     5581 caacagataa ctattcaact gactttcaga tttttacact caatgggtta tcagtaggcg
     5641 ttgaaaatga tttgttgagt gaagcattac gtgagttgcc agacaagaaa cgtgaaattc
     5701 tactgctgtt ttactttatg gacatgagcg attcagaaat tgcagacctg ttgaaattga
     5761 accgttctac tgtctatcgg catagaacca gtggactagc cttaattaaa aagtttatgg
     5821 aggaatttga agaatgaaaa cacaatatcc tatgattccc tttcctctca ttgtaaaggc
     5881 aacagatggc gataccgaag cgattaacca gattctacat cattacagag ggtacataac
     5941 gaagcgttcc ctacgactta tgaaagatga atatggcaat caaagtatgg tcgttgatga
     6001 agtcttacgt ggaagaatgg aaaccagact gattacaaag attttgtcat ttgaaattaa
     6061 gtaatatcct ctctcctttc gtggaagcgt gctaaaccat tccacgcttc ccgaacaggg
     6121 aggtttgtta ttccaccaaa gcatattgag ctttcaatgt gttttgatag gctaacgagc
     6181 cattgttctt tgaaaactga ataaaagtaa tcgaatacgt ttcgataaga aaagagccaa
     6241 cggaactaac cgccatgacc tatcttataa agatagcgag cgattcatgt tagtgatccg
     6301 agaagcaatc tttagcagga ttgcctgcaa cgacattctt atcgtgataa tgatactccc
     6361 atacagtcaa tagtccgagc gtgataaaac cgtcgcaggc aatgagtatg gctacatgag
     6421 aaccatgcag gggtggaact cccgtgagct ttgctaaagc tgttcgattg ctggtaaaac
     6481 aacttttatg aaatccaaat aagtgatttg gaaaggagga ttttatgaag cagactgaca
     6541 ttcctatttg ggaacgttat accctaacca ttgaagaagc gtcaaaatat tttcgtattg
     6601 gcgaaaacaa gctacgacgc ttggcagagg aaaataaaaa tgcaaattgg ctgattatga
     6661 atggcaatcg tattcagatt aaacgaaaac aatttgaaaa aattatagat acattggacg
     6721 caatctagcg tcgccaaagg gtcttgtata tgataaaata gtattaagtc gtatcaaggc
     6781 tctttccata aaggaaagga gcaaatgcca tgtcagaaaa aagacgtgac aataaaggtc
     6841 gaatcttaaa gactggagag agccaacgaa aagacggaag atacttatac aaatatatag
     6901 attcatttgg agaaccgcaa tttgtttact cgtggaaact tgtggctaca gaccgagtac
     6961 cagcaggaaa gcgtgattgt atctcactta gagagaaaat cgcagagtta cagaaagaca
     7021 ttcatgatgg tattgatgtt gtaggaaaga aaatgacact ctgccagctt tacgcaaaac
     7081 agaacgctca aagaccaaag gttagaaaaa acactgaaac tggacgcaaa tatcttatgg
     7141 atattttgaa gaaagacaag ttaggtgtaa gaagtattga cagtattaag ccatcagacg
     7201 ctaaagaatg ggctattaga atgagtgaaa atggttatgc ttatcaaacc atcaataact
     7261 acaaacgttc tttaaaggct tcattctata ttgctataca agatgattgt gttcggaaga
     7321 atccatttga ctttcaactg aaagcagttc ttgatgatga tactgtccct aagaccgtac
     7381 taacagaaga acaggaagaa aaactgttag cctttgcaaa agctgataaa acctacagca
     7441 aaaattatga tgaaattctg atactcttaa aaacaggtct tcgtatttca gagtttggtg
     7501 gtttgacact tccagattta gattttgaga atcgtcttgt caatatagac catcagctat
     7561 tgagagatac tgaaattggg tactacattg aaacaccaaa gaccaaaagt ggcgaacgtc
     7621 aagttcctat ggttgaagaa gcctatcaag catttaagcg agtgttagcg aatcgaaaga
     7681 atgataagcg tgttgagatt gatggatata gtgatttcct ctttcttaat agaaagaact
     7741 atccaaaagt ggcaagtgat tacaacggca tgatgaaagg tcttgttaag aaatacaata
     7801 agtataacga ggataaattg ccacacatca ctccacatag tttgcgacat acattctgta
     7861 ccaactatgc aaatgcagga atgaatccaa aggcattaca gtacattatg ggacatgcta
     7921 atatagccat gacgctgaac tattacgcac atgcaacatt cgattctgca atggcagaaa
     7981 tgaaacgctt gaataaagag aagcaacagg agcgtcttgt tgcttagtag tacaaatgaa
     8041 tttactactt atttaccact tctgacagct aagacatgag gaaatatgca aagaaacgtg
     8101 aagtatcttc ctacagtaaa aatactcgaa agcacataga ataaggcttt acgagcattt
     8161 aagaaaatat aaaaagataa ttagaaattt atactttgtt tcaaataaaa aagatgactt
     8221 actgaacctg taagccacct aatcagtcgg tttattctgg tgtctgccac cgcttggccc
     8281 gtacgtccaa gattgctatc ggattttgtt ctggtgtccg ccaccgcttg gcccttatgt
     8341 ccaagattac tatcagattg accatgagcc gaccactcat ttatagacat attgtatctt
     8401 taaatagcta caatttcaag tgtaaactct tctatttggt cgtataagca aaactgatgg
     8461 cactatctgc ttgagagatt tttctaaagg tatagttagg gttgccccca tagttggttt
     8521 cagacacaag gaaagaacca tcatcataga ccttctctac aaaagccaca tgaccatagc
     8581 tggctggtgt accatgtgta cctcctacaa aagaaacaat agcacctgct cttggtgtag
     8641 agcccgtttc cccaccaaga cttgaagctg tcgcaaccca gtcttgacca tttcccatgg
     8701 tattaatgat tgaaatcttt tctccatttc taccttttaa ttttaagcct aactggttca
     8761 tacgagccgc aacaccccat gtacattgtc cataagcata ggccatacca tctccaccac
     8821 caggaacaga atgatcatac aagtccccac gaaccccttc aagggattgt ggatcacttt
     8881 ttgcctgtcc tccatttgtt tgactaaagc ctttttcaat ttggtaatac cattccgttg
     8941 ctctggtttg tctttccagt agtttgtcac cagaatttcc ctcccaatag gtcagaaaga
     9001 gttgggcgag attggctgca ctgcccgtat ttccaaagaa atcctttaac caactttgat
     9061 agtaaggact gtccccgtga agcataaaat caagttggag gtctaaatca taccacttct
     9121 tattttgggt gtgtgcataa ttcaataaag ctgtatgacg tgttgaacca tctgcagtat
     9181 ctgtccattg ccctaaacct aaacctctat gaagaatatt aggataagca ccactataaa
     9241 tggctggacc tccaattgct aaccagcttt catcatccca tgaggaatcg gtagcgccaa
     9301 ctggaggaga taaataatct ccctcagctc gtttaggatt gatagaagac tctaccgacc
     9361 aatttcctaa aatagccgca atggcttgag gacttgcccc ttgagatttc aaaaactcat
     9421 aaatatgttt tgcacgttca aactcatctc caccaaactg accaatggca ggtaagatag
     9481 tggtctgaag ttgaatgacc tttggaaaat agaattgcgg attgacatac accaattttt
     9541 ctttcttgtt cttatacttt tgataggaaa ctttcaaacc tgtatcgtct ggtgtctcac
     9601 caataatatc accagtaaga actcttgtcc cctctatcgc acggccatta tgaatggaat
     9661 acaaggtcaa tcgactttca ttctctccat ttccgttagt gagaataaca ttatcaccat
     9721 ctagagatac aaccccatcc attggtgcga ctattgtttg gtgagcctta gcttctagta
     9781 gaatatactc ctgaagagta ggtttcccgt ctaaatcata gtatccataa cgatacgtca
     9841 tggttagact atcttcgttg cttttcccct caaatggatt gtccaattcc tgcatggaag
     9901 catagacacc ctcttctttt agttccttta tttcctcttg atcgtctctc gatagtttat
     9961 acttaggagt ttcatagagg tcttgcatgg atttcaaatc ttccccatcg tttaaatcat
    10021 gccacaaagt agacagataa tccttgtaag tttctgaact aaataagtga actggtttgt
    10081 gtaactcata gtcatggaat ttaaagttca tatatcccat cacatcatca atttttgtgt
    10141 aataagtaat tcctttgtca tttgtgcgag tatgttctgc atcttcccaa gttaggtggg
    10201 tataagcttt tgttaattca aattcatctt gttgaatcaa actagcagat gaaaatccta
    10261 aaaagaagct catcataagt aaaagaagaa agactattcc tccaactatc caggttacag
    10321 gatttccagc cgcaaatgta aagaaggaaa aggctgcttt tagtttttga tagatgtttc
    10381 ggacacttgt aagaccttgt ttctttaatt ttcgaaaccg atttttaaag gaacttggat
    10441 tctctttcgc tagtttccat ccttttccat ccttaaaatg atggtatcgc tcttttgtgt
    10501 tggtcagtct tttcttggta aaacgacctg ttgcttgtcc tgttttgaca ctagcttttc
    10561 caagattata agaaagccga ctgtagcgtt tcccttttct gatggtctca tgaagtgtgc
    10621 gataactttc taaatcttca ttttctgaag ctaactctcc accttcacgt ccaaggacat
    10681 aaagaaaggt tttggctttc ctactgattt ttttgaactt ataggcttgc ttagtagatt
    10741 ttagattctc ttttgcggct ttgacttctt tcttagattt gaattcttct aaactcttcc
    10801 cttgaaagaa aaaattggat tttgctttcg attcctgacc gtagagaaat ttttgattgg
    10861 tttttctttc tttacgactc tcttttcttt cttcttttgc ttcaacctta gcttccttaa
    10921 attgtttctt ggctattttc aatcgtttcc tagcatgagg caatcgtcta tctcttaatt
    10981 ctttccgatt caaaagtgat ggaggactat tttgaagaat atgattgtag tcttcatttg
    11041 cttgttttac tctagccttt gaagcttctc tcatctcctc tagcttttgc tttatctcat
    11101 ttttccatgc tttttcatcc agtacagcgg aatctttttt ctgttttctc acctccttct
    11161 ttcctttttt caagaatttc ttctcatctt ttagacttct tctaaatgcc tttcgtgcac
    11221 gtatgatttc tcttttatcc ttcatttacc ttccccttaa ttagaagcca ttttatcagg
    11281 atctgtactc ataatatcaa acaattgagt accttgagga atcttatttt taaagggaac
    11341 gacaactgaa ccagctttta ttagtcctgc ccctttttct ggattgacta ggtatttttc
    11401 gagttctttt gacaagccta agagttgaac cagttcttct cggtcatttt ttgcttgctt
    11461 gaggagaatc ataaattcac tattggcaat aatccgtcta ccatttggat ctaacaataa
    11521 ggtttcgaca ttttgggtta tcccagtcgg actggctcca tattttctga cacgactcca
    11581 caatttaaag aagaaatcac tggcatattt atctaataaa agaagctgca tttcatcaaa
    11641 ataaatccaa gtcttcttcc ctaatttttg gttccgaacg acacgattcc atatctgatc
    11701 aaaaacaacc ataagagcga tttgtttcag ctcatctcct aactttttaa cgttatagat
    11761 taagaagtta gatcctgtct gaatattggt cttatgagaa aaaatatcaa gagaaccttc
    11821 aacatacagt tccatatcaa gtgccaaatt ctgcgcttct tcttctggtt gttggctcaa
    11881 gacaaagacc cattcttcca aagaaggctc tttaaatgac tgataggtga gtctggtaac
    11941 tcggtcgata atcgattttt ctctcccatc catttttcta tccaataact taccaataaa
    12001 agataaaaga aattctgatt ttacctttac aggatcctca tccatatttt cctcagacaa
    12061 gtcaagtaca tttagataag tctgggagtc gggcgcaata tcaatcattt ctccaccaaa
    12121 agcccgtcca atgacactgt attctgcttc tggatccacg atgataattt ctgtattttc
    12181 accagattcc ttgattttgg tcgtgataat ttcatgcttg gttgccatcc cttttccagc
    12241 tccagatgtt cctaaaatca gaccagatgg tgtatttaat aggctacgat caatggtaat
    12301 aatattgctt gatatttgat tgataccgta atatttccca ctacggtctt gtaaatcgac
    12361 tgaagtccat ggagagttca ctgctacatt ggacgttaat aaactccgtg atactccctc
    12421 taaaaaatca caaccaaatg gcagcaaact attaaaggct gcttcttgca tatatggaag
    12481 tttatcaatc attaggtcat ttgagccggc cacttgttga atcgtatcta gtgcttgttt
    12541 gagttcttct tcatcctgac caaaaacacc aatcaagaag acagtttgaa atagtttatc
    12601 tcctgtctcg gtcatggttt ttaagagttc ttcagcttca tcgatattgc tttctaatac
    12661 atgacctact ttttccaaat agatacctgt acgagctagt ttttgttgtt ctcctatctt
    12721 ttgggattcc atcaaggtct tctttgttcg tagtttcttc atggcatctg ccttggtcga
    12781 actttgtgca tggaggctca caatcaattc caaatctcct tgcatgaggt ctcgaataaa
    12841 ctgatcccct aattccatac cgtagtctct cacatagaca atctgcaata agcggtcatt
    12901 gatttgtagg taattcttgt ttttaaaatc caagaggtta ggagctataa agtgacgagt
    12961 tgtctgacca gatctcgtta aatcacggta agaaaacgga agatggtgtt ctcctctaag
    13021 catatccgcc aacaagttga cacgctcttc accagccaag gattcaaaac gtgcatcaat
    13081 ttctgagaaa ccactcttga aatattctcc tatttgggac aaggaacgat aagcctgttt
    13141 gggattagaa tcctttctac caaagctaat cagtttcaca gctgaaaagt tattttcccc
    13201 actgtctaaa ttttgattca tcatcctatt caattcttga cgatagctat catacccatc
    13261 ttctttttcc tcatacaaaa cactttgtct aaacttttct aaattcaatc ttttattaaa
    13321 gatagtcaat tggaagttgg tttggtcatc taaggagtta atcaaatcag aatacttctc
    13381 aatgattgcc cccttatctt ctaaaccaac ggtctggtaa ttgacatcac caagtaaata
    13441 gctttgtgag aaataatctt cttttacctg catcagacca ttttgataca gggcttgata
    13501 ggaaagagta ttagccgtag agggtaacac ttcctctttt tttcctttaa ctacttcttt
    13561 ctgattagtc attgaagttt tttgtttctt taatgtattt gattttcttt tcatgttcag
    13621 atcctttctt tcctgtaatt gtgcgtaggg gaaccgttag ttcaaaatga agacggtatt
    13681 tcaaataatg ttcaaaatat aaatcattgg gtttatagac tccaaaaagc attaggggga
    13741 tggtaaaagc aaacacaaaa ccgtaaacaa accaatctcc aaattgccag aaaaagagat
    13801 tcaagcccaa aacaataatt gtgacaataa aggctggtaa aacaaagatg atttgtcttg
    13861 tggtgaaacc taaccaagcc ctgtgttggt attttgagat gtctttaaag acacgtgtat
    13921 tcatgacttt cctttctaaa aaggctaaga agcaatcact tcctagcctt tatctaatta
    13981 catacctaag attgagcgag ccgtacgttg agaaccaacg agggcaataa tcagtaagat
    14041 agcttgtatc aaactaccaa acataatcgc aagtgattgc aggactcctg caccatttga
    14101 aacagctatt ttcccagcag attcaaacaa aggaacaaga gaaacaatca gaaaaataag
    14161 aaccccttgt accgcataga ccataatatt ttttaaatag ccaataccaa tagacttcca
    14221 ctcatcactt aaaaatgttg gaatcgtaag aggggcaaat ggaatcataa ggtaaagttg
    14281 aataaatcga atggatacca aaagattgac catggctgca cttactatcc gaacaagcca
    14341 aattaggagg gcgaaaaagc ccacaatcat ccggccaata aatcctgaac cttttagtcc
    14401 agagattgta tcatactttg ccccaccgtg agccacaatc gaagccactt gttcaatggc
    14461 gtgactcgca atcccgatga tggcttctac aataacggta gtgttggtaa tcacgactgc
    14521 gaccatgata taactaatca acatcggcgc taatgcttca aaggtcatcg ctccaccaga
    14581 gttagcaatt ttctttgcca tctttgaaaa ttctaagatg agaacaactg ataaaatcgc
    14641 aactccaaga ggctgcatga cacttttagt aatactagac atataagtcc aaactgttgg
    14701 attgtagcta gatagagatt taatcagatc taccgtagat tgtaaatcca cattaaatcc
    14761 ttcaaataaa ttttcagccg atattttttc agatgcaagg taaataaagg gtgagactaa
    14821 actaagattc atgtcattgt ttatcctcct aaattgaaat ctgggttaca aaggctccag
    14881 cagccccgac cataacacca ccgacaattt ccagaatggc attccgaaca cctggtccac
    14941 catctttaat gttggttgca aggttaacaa tccccacaac aacgagaaag gcaccaaccg
    15001 caatcaatcc cttctgtaac aaagacatag cttgtgcaaa catagcactt gcgtctactc
    15061 cataaacaaa acctttaaaa tgcgtaatca tctatttcct cttttctatt tttattttaa
    15121 actagattca aaagttaaat cacgaattct aaggccttca agatgatttt cttgtctttg
    15181 attcaaagga ttgatttgat agttccacca ccgttcatcg ctttcttgat tggctaggta
    15241 tttccagttt ggatgcttaa tggaattgta ctttttgctt ttaaagacag gcatattggc
    15301 aattcgaacc aagcattcat gccgtttcat atttccgact tcatcgggtg tcattaaatc
    15361 acgagcaatc ttttgatgag aaagggatcc tgaacctgtc tggccaaagg aacgactagt
    15421 atttcgaaca tcaatggttt gtttaccgag taagccactc ataaatttaa aggtatcttc
    15481 atcattacca cctaagtaga ctaagctatc acagttccca agaatggttt tccaagcttc
    15541 tttttcttta tagagccctt gaagttgggc aatattttga agaatgggaa cgagactcat
    15601 attccgagaa cggactgttg aggtttgttc agcaaaatct gggatttctc cgatatttgc
    15661 gaactcatct aaatagactc tcacatgaag aggtaattga cccttaaaat caatatctgc
    15721 ttgtcttgtt agggtttgaa atacggttga aaaaaagagg gctgaaagaa agcgaaaggt
    15781 actatcgtta tctgggataa ctaagtaaac cattgatttt tcctggcccc atgtcttcat
    15841 atcaagggta tctcttttgg tcaaatccat gacactttga atattgaaga gggcaaattt
    15901 agcagtggtt acagctataa cagaatctag tgtcttgtcc ttataatttt gaaaatctgc
    15961 ccaatttcgc atggtaaaat tttcagtccc atacttttta gcataatttt caaatagaat
    16021 ttctaagaca cttttttcct gattttcacc tttggataag tgtttaatga gttttgaaat
    16081 ttcagcaaaa cttggataac gccctcgttt ttttcgctct tccacttctt ttttttgacg
    16141 tttcaacaag ttttggtatt ctgtttgact caaacgactt tcttctatga gctgttctct
    16201 tgttttaggt ggattataga aatcgaccaa gtaagaggct aaagctcgaa ccaaagtcat
    16261 agaagcttca tcccaaaatg gatcactacg ggagccagag cctttagtgt tattaaaata
    16321 aaccgtcagc atgcgattca aatcgttttc tgtctctata tagcgaaaag gattgaagcc
    16381 atctgagttc ttcatattga ctaaatctaa tacctttact tggtagccat gttctataaa
    16441 gagtttgcct gttttctcag ctaagtgatc tttaggatct actacaatat tagaactatt
    16501 catctgaatc agattgggtt tcacaaagcg aaatgtcttc ccacttcctg aacctccaat
    16561 caccgcaata ttcttatttc tatcatattg tggtggcttt ttatctaaca aagttagacg
    16621 aacatcttga gctaagatcg tatcatgaga aaattcctta ccgtaaaaga gcttcttttc
    16681 ttttagagtt ccaaaacggg cgctcccgta ttctacccct tctcggtatt gttttttacc
    16741 agtctctaga tagagataaa ccagcaacat catcacaaaa cctagtagaa aaaaagcact
    16801 tgattttcca gtaaaggaaa cattccatgg cgactgaaga acttcatctt gaccttccat
    16861 cagaagatga gtccatttat ctaatgtatt tccagtatag gaatcataca aaagcgtcaa
    16921 acgatgaaaa agatagccta gtaagatacc taacagtgag aatagtagga atttctttcc
    16981 actgtacatc atctcaccat ctctttctgt ttgacggccc cttcttgtct aaaggtaatt
    17041 tgagatttag cctcatcaat tgcatcgtct aatgacttat ccatagtaaa atcagctaat
    17101 ttctccggat cattaaccat tttttctaac agatggtcta aatgattgtc tagaatcgaa
    17161 cggtctttcg tgtagaaatg tagagaatcc ccttgccaag cgatggctaa aggaatctct
    17221 tctttttcta aaaaagcttt aaatttctct atatcaattg gtttgtctaa gaaatctttt
    17281 ttcagattaa tcgtatcaat cgaataagga gattgtagca attcttctaa tttctgtact
    17341 cctatcttat aggcagaatc ctgtgataaa gcctgacgtc tagaccattc tagaatcttt
    17401 aaaagacttt tgacagtgaa taaaagacta cgctcagcat attgaactgc cattcgttcc
    17461 tgttgttcag aggacatctg atgcctcctt cttaacaaat agcagctttc cttctttata
    17521 acgataagct atcaatttct gacgttgctt aatcgacttg acaacctgca gtagatctct
    17581 cgaataaggt tctcgaagag taacttctac tgctttccca tcaatgatac caacacgttt
    17641 aaattcaatg tagtcttttt tgagatgtcc taagcccata ccaaagggaa agtgatgaat
    17701 caattggatg gtacaaccac ctttatttcc catttgtttc aaatcataca agtttactac
    17761 cttcatgatt aactccttta tctagtttgt cgcatcgttt aagtctggta acgataaact
    17821 ccgtgtctgt tagaaaattc tcacacacgt cttgtgccag ttgcccttca cagggaaata
    17881 ctctcagtcc ctacttacac aggcacgcta atcaagacgg agtggattca attttcaaag
    17941 aacaggtagc tttattatag ataagagtag ttgaaatttt tatcacattt ctaatttttc
    18001 tgtcgagcta aattcatact aaacaaagat tttgaaataa aagactaaca ttatgaaata
    18061 acgttagctt ttcatttccc taaacaagca gcaaactata aactagtagg ttccacacca
    18121 aatgtagctc catactgccc cataaatcag atttatagcg caccatccct aaaaacatcc
    18181 caagtgaaac atacaaacac caagctagaa tggttccagg atgatgtgct aaggcaaata
    18241 aaacgcttgt caaagcaact cgaatatcta attttctaac caagttccat aaaatttctc
    18301 gatacagaaa ttcttcaacc atactcgcat tgattaagaa caataaaaat gaaaaccaag
    18361 gaacttgatg ttgaatgcca attaagtttg cttgattcgt acttccttga gcatgaatca
    18421 ggctaaaaca tagacttata atcagtaggc taacaaatcc aacaccaagc catttcatcc
    18481 tagttttcat atcgatttta tgcgcttgtt tacgttgacc atacatccat aaaaaagaaa
    18541 tgagcgaccc acaatagaga atctgtagta tagttaactc accgctacaa agaaatttca
    18601 gtaagtatag agataccaat aggatattta cttgttggaa tatataaact ggaattattc
    18661 ttttcatagt tacctccgaa ataaatcttc ataatctaaa tctaatacct gcacaatcct
    18721 ttctacccat ggactttgag gcattcgttg ttccaccttg tagtgccgaa ttttttgata
    18781 caaacgattc aattcacttg gatagtgaaa ctctcccgca aacatttttc tggttaactc
    18841 aatccagctg atatttcttt cagccaaaat aatggacaag ttctcccaaa atcgttcagc
    18901 catattgctt ctcctttagt tagataaata atgtgtttgt gccatgtaaa tcaattgttt
    18961 cgtatctctt ggcaataaag ctctagcctc ttccaaattc agattcggat aaacccgctt
    19021 atttgaaacc gcaagaggaa gtctgatggt tagttcagga ttttttaaaa tcatctcaac
    19081 gaaatccgtt aatcttagat tgtcacggtt cttaaatcgt aataaattgg gagataaaaa
    19141 ctcaaaacaa tctgaagaat agctcatcat ctcaattaat ttgtcctttg tcatttcaga
    19201 aactgaatgg caagatactt cgataccata gttttggaag aattctaaaa gaagttgatt
    19261 tctatggcta tttttactta gatagagatc aatcatggga gacctcccac tgattcgctt
    19321 caatttgata ttctgagacg attaaggaat ctaatgaatg tgagaagtta attgatttct
    19381 tgtcttcatc ataagctttt acagttactt gggttgtaag tattccctct tttccctctg
    19441 ctcgataacc ttgtccatat aaaataaaaa cgagattttg atgatcatct acaaaggcat
    19501 caactccatt ctttatgtct tgactttcaa ggaattccat aacgttttga agataggatt
    19561 cgtaaaatag tgggtagttg tgttttttat ggtaatcatc taaaaatttc acttcaaact
    19621 cacatggata attgggcatc aaaaatattt gttcatccaa ctgcatcatt tctgcatcat
    19681 gtaattctgt ttctaattca tcacaatcta gtattgactc tttatttaac gctttcatct
    19741 ttttcctcta tttcttttaa tttctttgcg attgcagcaa tcacaggaac ggttacacta
    19801 ttaccagctt gtttatagag ctgactatta ctagagactt ttctagcagc ttcaaaagcc
    19861 caatcaggaa agccctgaag tcgaaaacac tctttagggg tgattcttcg tatcctcaaa
    19921 cggtaaaatt gcccatcaat taagacaccg gctacatgat aaacttgttt atcttctcct
    19981 tcatagctag ccactactac tcccatttga ccactagttg ttaacgtatt cgctatacct
    20041 tttccaactc tacctcgacg atactgagaa cttggtcttt ccaaattgat ggaatcccca
    20101 atctctgctt gagcatatcc ttttttcgtt gcttcccgta cttttagaaa ttggattggt
    20161 tctggaatca gtattttggg gattttatct cctccttgca tcgtagtcag tgttggagat
    20221 aagccctcac ttccatagac gcgaccagtt tccttaaagc tagttggtaa atctccaaca
    20281 acgacaatac catggcgatc ctgagtattt aaagtaaaca ttggctcttg attatccttg
    20341 aaacgtctac cattttgtct tttttttaat ctgtctggtg tcatacaagg aatcgcaact
    20401 ttaaatcctt ctccttttcc acgaactaag gttggcgcaa gaccttctga ataatagact
    20461 ttaccgctca ttccactttt tgatggattc aaattcccta atatttttaa agtctcagag
    20521 ttagttgctt gaccttctcg tctgaaagga aataggagtc tggtacctct ctttctagaa
    20581 tgtccgataa taaacaccct ctctctgttt tggggaacgc caaaatcctt actgttaagc
    20641 acctgccact caacatcaaa ccccaattca tcaagcgtgg taaggattgt ggtgaacgtc
    20701 cgtcccttat cgtgattgag taggccttta acattttcaa gaaaaagaaa acgtggttgg
    20761 atttgtttgg ccgcccgagc aatttcaaag aataaagttc ctctagtatc ttcaaatccc
    20821 aatcgtcttc ctgcgattga aaatgcttga caagggaatc ccccacagat gacatcgact
    20881 ttccctctaa gttttttaaa ttcgtcatct gaaacatctc gtatgtcatg aaattcaatt
    20941 tctccttccg tttgaaaaat ggacttataa gattctctag caaatttatc aatctcacaa
    21001 aatccaatac actcatgtcc aacactttcc attccaagtc gaaaaccacc gatacctgaa
    21061 aataaatcaa taaatctcat ttctttatca cccctttctt atcgactacc attgtcaaaa
    21121 ctgtcactcc acttgaaatg acaataagca taactaatat ccactcgatt ggcgacattt
    21181 aaccacctcc ttttctaaca cggttattcc aaacagaata caagccatta aacacaaatt
    21241 cagcaaggac ttcagctcgc ctaacaaagc gaacattgtc aagagcatac tgatagattc
    21301 tctcaaaatc ggtcatagca atttcactag ctgtttcaga aaaaccttct cgtctaaatt
    21361 gatcttgtac caatccccaa atataatctc gatcatattt tgtgaccttt tctacttttc
    21421 ttctcaaaat aggttgagaa ttcctttctt cctcatcctc aataaataaa gattcagtct
    21481 cactatattt agtctcacta acttcagtct cactaggggc tgaataagag acgggggccg
    21541 cttcattttc atcctggcat agtctttttt taacactagg cctgttcgaa ctagctactg
    21601 gggtagaaga caactcccct aaataaatct tattagctag tctccctttc tcacttgaag
    21661 actgttggac ttcatcaatt aagtcatatt ctttaagaat ttttttgatg gacagtaatt
    21721 ttgacttcga acaacctaat agcttcatca ggttagaatt agaaaatact aaataaaccg
    21781 ctccttcttc atctatccaa ccacgactga gagataattc taaacgatcc tttaaaatag
    21841 aataagctac ctttacttct agtttcatat ccatatattt ctcatcctca aaaagaattt
    21901 taggtaattt gtaataccgt tctgaagttt gatattgatt tgcggttatt cgtttcataa
    21961 cgctcctcca agttctttga gtattaaatt tccacttgat tccaatcgaa ccaagccact
    22021 tttttccaat tcagccataa gagagatggc ctcaacaata tctattccca tttcacgtac
    22081 taaaaatgaa atgacaatat agcgtgatga ttgtaattcc tttgtcattt tccctcctga
    22141 aaataaaaaa aggagaacaa tattcaactg ttctccaaaa taattttatt aaaaagaaaa
    22201 accctgccaa attaattttt ggtag
//
LOCUS       DAUCXI010000031        22083 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.031, whole genome shotgun sequence.
ACCESSION   DAUCXI010000031 DAUCXI010000000
VERSION     DAUCXI010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22083
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.031"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            21..3236
                     /gene="rexB"
                     /locus_tag="VGY43_001267"
     CDS             21..3236
                     /gene="rexB"
                     /locus_tag="VGY43_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEQ4302448.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVPTVINETFDDLSPYLKELISFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIP
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIKVIDQE
                     KNFHLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLATYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMAQARRLVTLPAKEKKECFLTLMRKESHL"
     gene            3197..6865
                     /gene="addA"
                     /locus_tag="VGY43_001268"
     CDS             3197..6865
                     /gene="addA"
                     /locus_tag="VGY43_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEQ4302449.1"
                     /translation="MLFNINEKGEPLVISFAPFLSPEAIKHLQENERCSDQSQKRTAQ
                     QIEAIYTSGQNVLVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDY
                     GQLTKAGSRSAKFTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDIAHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFGE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQD
                     ITDPKKLGKLLSLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
                     QIPQLLNADDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKVDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            7005..7817
                     /locus_tag="VGY43_001269"
     CDS             7005..7817
                     /locus_tag="VGY43_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEQ4302450.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHHERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLNGKKVAAQKGSIE
                     EGLVKIQLPKANLISLTAMGEAINELKAGQVYAVTLETPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            7958..8134
                     /locus_tag="VGY43_001270"
     CDS             7958..8134
                     /locus_tag="VGY43_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEQ4302451.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(8262..8624)
                     /gene="mscL"
                     /locus_tag="VGY43_001271"
     CDS             complement(8262..8624)
                     /gene="mscL"
                     /locus_tag="VGY43_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEQ4302452.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            8754..10568
                     /gene="dnaG"
                     /locus_tag="VGY43_001272"
     CDS             8754..10568
                     /gene="dnaG"
                     /locus_tag="VGY43_001272"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ4302453.1"
                     /translation="MGFLWGGDDLAIDKEMISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNIPPSQAVLASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYEEGQLVASGLFNLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADTEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRMPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKIADLLPNFDYFQVEQSVNALRIQDRQK
                     RQGQIAQAVSNLVTLPMPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     ELLYQRLKQQGHITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            10577..11686
                     /gene="rpoD"
                     /locus_tag="VGY43_001273"
     CDS             10577..11686
                     /gene="rpoD"
                     /locus_tag="VGY43_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEQ4302454.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            11923..12261
                     /locus_tag="VGY43_001274"
     CDS             11923..12261
                     /locus_tag="VGY43_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEQ4302455.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            12399..13253
                     /gene="rfbD"
                     /locus_tag="VGY43_001275"
     CDS             12399..13253
                     /gene="rfbD"
                     /locus_tag="VGY43_001275"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEQ4302456.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEYFYIIRTAWVFGNYGKN
                     FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            13372..14526
                     /locus_tag="VGY43_001276"
     CDS             13372..14526
                     /locus_tag="VGY43_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEQ4302457.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSKPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLTTADSKVRAYFQTFDIREKDYYLILGR
                     FVPENNYEAAIKEFMASSTKRDLVIICNHEGNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQSVAKSAALYWSK
                     QKGQLAELINQVDAGFDSDHLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            14516..15448
                     /locus_tag="VGY43_001277"
     CDS             14516..15448
                     /locus_tag="VGY43_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ4302458.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMAAPLLVYTDLKVVTQHLAICHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLTPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            15451..16254
                     /locus_tag="VGY43_001278"
     CDS             15451..16254
                     /locus_tag="VGY43_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302459.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYIVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            16254..17459
                     /locus_tag="VGY43_001279"
     CDS             16254..17459
                     /locus_tag="VGY43_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302460.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            17484..18491
                     /locus_tag="VGY43_001280"
     CDS             17484..18491
                     /locus_tag="VGY43_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ4302461.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTIYRMTTDSDSR
                     PTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKEVSKLLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            18488..20233
                     /locus_tag="VGY43_001281"
     CDS             18488..20233
                     /locus_tag="VGY43_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEQ4302462.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGPIW
                     EMAPYFENFEEKETVDFWGITNNRGTKAFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDAKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSAFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLLVYI
                     AWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            20230..>22083
                     /locus_tag="VGY43_001282"
     CDS             20230..>22083
                     /locus_tag="VGY43_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEQ4302463.1"
                     /translation="MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPV
                     NYYTHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPSLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVTAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLNSNKSSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNITDQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVG"
BASE COUNT         7359 a         3653 c         4205 g         6866 t
ORIGIN      
        1 agtttgtata aaggagtcat atgaaattaa tttacacaga gatgagttac tcgatgacag
       61 agattttggt gaatgaagca cgaaaagctg ctgaccaagg ttatcgagtg ttctatattg
      121 ctccaaattc tctttcattt gaaaaggaaa gagaagtctt aaccttattg cctgaacgag
      181 ggactttttc gataatagtc acccggttcg ttcaaatgtc aaggtatttt acagttgaga
      241 gctctccttc taagcaacat ctagatgaca cgactttggc tatgattttt tatcgggcct
      301 tgatgcaatt aaaaccagaa gatttgccga gttatggtcg tttgcaaaat aattcggttt
      361 ttattgaaca actagttgag ttatataagg aattaaaaaa cgcacaatta agcgtacatg
      421 atttaacagg attagaccat cctcaaaaac aagaagatct tattaaaatt attgagcttg
      481 cagagacgat catgattcag caagattata atcaagatag tcctctacaa tcttttgcaa
      541 gagcaattaa gttaggactt ttaaataacc aactatcaaa aacagttgtt gttattgatg
      601 gtttttcacg tttttcagct gaagaggatt atttattatc acttttaaat aacaactgtc
      661 aagaggtcat cattggcagt tatgtgagtc aaaaagctta tcaaaaatct tttattaagg
      721 gaaatatcta tgaggctagc cttcattttt tgcaagattt ggctcaaaaa taccatatca
      781 agccggtatt tgcgacctct aatcaagtgt ttaaaccagc cttttcacgg ctaacacaat
      841 tatttgaagc aactcatgat ttttcacaag tagactggca actccaaaag aatgatcttg
      901 atcactttag cctttggcaa tgtcatcatc aaaaagagga aattgaacat gtagcaaaat
      961 ccattcggca aaagctatat gaaggttacc gttataagga tatcttagtg ttgctaggag
     1021 atatggatgc ttatcaatta caaattgggc ctatctttga taagtttgaa atcccctact
     1081 atttaggaaa agcagagcct atggctgccc atccattagt ccaatttata gaatcgctcg
     1141 aacgaagtca gcgctataat tggcgtcgtg aagacatttt aaacatgtta aaatcaggac
     1201 tttttggttg ttttgatgat agtgatattg atcgctttga ggaatatact cagtttgcag
     1261 atattaaagg gtttactaaa ttttcaaagc cttttaccat taactcttct aggcagtatc
     1321 ctcttgactt tttaaatgaa atgagacaag acatcgtttt acctttgcaa gaattgttta
     1381 agagtcaaaa acaacttggt gcttcacttg ttgacaaatt aatacttttt ttaaaaaaga
     1441 ttagattagc tgagaatatg caaggtttag cacagtccca attagaggtg gaaaaaaacg
     1501 aagaagtttg gaaaaggttt acagatattt tgacttcttt tcatcatatc tttggccaag
     1561 aaaaattacg gctatcagat tgccttgctt taatcaaaac gggaatgaaa tcagctcagt
     1621 atcgtgttgt tccagcgaca ttagatgttg tcactattaa atcttatgac cttgttcaac
     1681 cacattcaaa acctttcgtt tatgcaattg gtctaactca atcacatttt cctaagcaaa
     1741 ttcaccattc aggactactt tctgatcaag agcgtgctag aattaatgaa ataagaaatt
     1801 atcgtcattt tgatattgct agtgccgaaa atagtaaaaa aaaccatcaa actgcgttat
     1861 ctctgtttaa tgctgctact aaagagttag ttcttagtgt tccaacggta atcaacgaga
     1921 cattcgatga tctatctcct tatcttaaag aattaataag ctttgggcta cctcttttgg
     1981 ataaaggcaa aaactatcta tcttatgata atagcgatat tggtaactat aaagctctct
     2041 tgtcacaaat tattgctatt aaccgacaag atcttataga aatgtcagat caagataaga
     2101 tgttttggac tgttgtctta cgttatctca ggaaacagtt aagaaagcaa cagctagagc
     2161 tacctacttc agattatcgt ttatcaacaa agcctttgtc taaagaagtt atcgaggtat
     2221 gttttccaaa gggaatccct ttaaagctat ctgcaactgc tttaaccgtt ttttataata
     2281 atcagtacaa ctattttttg aaatatgttt tgaatttaaa caaaacagaa tccattcatc
     2341 cagattccag aattcatggt caatacttgc atcgtgtctt tgagcggtta atgaaagatc
     2401 acacgcaaga accgtttgat aataaattaa aacaagcaat ctaccatacc aatcaagaaa
     2461 gtttttttca gcaggtttac caagataatg ccgaggctga gtacagttta gctatactag
     2521 aagatattgt tagatcaaca gcacctatct tgcaacttaa ccaaaacata aaggtcattg
     2581 atcaagaaaa gaactttcat ctggatatgg gaaatgagat attagtccac gggatcattg
     2641 atcgtattga ccagctgagc gacggtagct tgggcattgt tgactataaa tcaagcgcga
     2701 atcaatttga tattgggacc ttttataatg ggttgagtcc acaactagcg acttacctcg
     2761 cagccttaaa acagatcgca ccgcacgata taaaccaatt atttggggct atgtaccttc
     2821 atttgcaaga tcctaaattg gatctagtaa catttaaaca aattgataac acattagtgg
     2881 agagtatcta taaagcgttg acctataaag gtattttttc agaagtcgaa aaagagcatc
     2941 tatctactgg tgcttaccaa accaaaaatg ctctttattc caatgacgaa ttggaaacac
     3001 ttttaaatta taacaagtat ctctatctta aagctgctaa acacattaaa aagggacatt
     3061 ttttgattaa tccttataca agcgatggta agacagttca aggagatcaa ttaaaagcca
     3121 ttacccgttt tgaagcagat cttgacatgg cacaggcaag gcgactagtg actctccctg
     3181 ctaaggagaa aaaagagtgc tttttaacat taatgagaaa ggagagccac ttgtgatttc
     3241 ttttgcccca tttttaagcc ccgaagctat taaacattta caagaaaacg aaaggtgcag
     3301 tgatcagtct caaaaacgca cagctcaaca aattgaagca atttatacta gtggccaaaa
     3361 tgtacttgta tcagcttctg ctggttcagg aaaaaccttt gtaatggtcg aacgcatact
     3421 tgataaaatt ttgagaggtg tttcaattga tcggcttttt atctcaacct ttactgttaa
     3481 agcagctaca gaactgcgtg aacggattga aaacaaatta tactcacaaa ttgctcaaac
     3541 tacagatttt caaatgaaag tttatttaac agaacaattg caatctcttt gtcaagctga
     3601 tattggtact atggatgctt ttgcacagaa agtagtaagt cgctatggtt atagcattgg
     3661 catttcatcc caatttcgta tcatgcagga taaagcagaa caagatgttt taaagcaaga
     3721 ggtgtttagc aaactcttta gtgagtttat gaatcaaaaa gaggcaccgg tgtttagggc
     3781 tcttgtgaaa aatttttctg gtaactgtaa agacacttca gcttttagag agttagttta
     3841 tacttgttat tcttttagcc aatcgacaga aaatccaaaa atatggttgc aagaaaattt
     3901 tctaagcgct gctaaaactt accaaagact tgaagatatc ccggatcatg atattgaact
     3961 cttacttttg gcaatgcaag acactgcaaa tcagctaaga gatgtgactg atatggaaga
     4021 ttatgggcag ctgactaagg caggtagccg atctgctaaa ttcactaaac acttaacgat
     4081 catagaaaag ttgtctgatt gggtgcgtga ttttaaatgt ttgtatggaa aagccggatt
     4141 ggatcggttg atcagagatg tgacaggcct tataccatct gggaatgatg ttacagtctc
     4201 gaaggtaaaa taccctgttt ttaagacctt gcatcaaaaa ttaaaacaat ttaggcattt
     4261 agaaacaatt ttaatgtatc agaaagactg ttttccctta ttggaacagt tacaagattt
     4321 tgtgcttgcg ttttcagaag cttatttagc tgtcaaaata caagaaagtg cttttgaatt
     4381 ttcagatatt gcacactttg caatcaaaat tttagaggaa aatacggata ttcgccaatc
     4441 ctatcagcaa cactatcatg aggtgatggt tgatgaatat caagataaca atcatatgca
     4501 agagcgactc ctgaccttac tatcgaacgg tcataatcgc tttatggtag gagatatcaa
     4561 acaatcgatc tatcgatttc ggcaagccga tcctcagatt tttaatcaaa agtttagaga
     4621 ctatcaaaaa aaacctgagc aggggaaagt gattttactc aaagaaaact ttcgtagcca
     4681 atcagaggtg ttaaatgtca gcaacgctgt ttttagtcac ttaatggacg aatcagtagg
     4741 agacgtctta tatgatgagc aacatcagtt aatagcaggt agtcatgctc aaacagtccc
     4801 ctatctagac cgtcgtgctc agttattgct atataatagc gataaagatg atggcaacgc
     4861 cccttcagat agtgagggta tttcatttgg cgaggttaca attgttgcca aagaaattat
     4921 taagcttcac aatgataagg gtgtcccttt tgaagacatt acgttactcg tttcttcaag
     4981 aacaagaaat gatatcattt ctcatacatt caatcaatat ggtattccta tagtaacaga
     5041 tggtgggcag caaaactatc ttaaatctgt tgaagtgatg gttatgttag atacattacg
     5101 caccattaat aacccaagaa atgattatgc ccttgtggct ttactgcgct caccgatgtt
     5161 tgcctttgat gaagatgatt tagcaagaat agcacttcaa aaagacaatg agctagataa
     5221 agattgccta tatgacaaga tacaaagggc tgtgattgga agaggtgctc atcctgaatt
     5281 gattcacgat accttgcttg gcaagttaaa tgttttttta aagacgttga aaagctggcg
     5341 tcgatacgct aagctagggt cgttgtatga cttgatttgg aaaattttca atgatcgttt
     5401 ttattttgat tttgtagcta gtcaagcaaa agcagaacaa gcacaagcta atctatacgc
     5461 attagctcta cgtgctaatc agtttgaaaa atcgggctat aaaggactat accgttttat
     5521 taaaatgatt gataaggtac ttgagacgca aaatgactta gcagatgtgg aagtggctgc
     5581 tcctaaacaa gctgttaatt taatgaccat tcacaagtct aaaggtttac aatttccgta
     5641 tgtatttatc cttaattgtg acaagcgctt ctcaatgaca gatattcata aatcatttat
     5701 tctgaatcgg cagcacggta tcggtatcaa gtaccttgca gatatcaaag gtttacttgg
     5761 tgaaacaaca ctcaattctg ttaaagtaag catggaaacc ttaccttatc aattgaacaa
     5821 acaagagtta cgcttagcaa ctttatcaga acaaatgcgc ttactgtatg ttgctatgac
     5881 acgagctgaa aaaaaagttt attttattgg taaagctagt aagagcaaaa gtcaagatat
     5941 cacagatcct aaaaagttag gcaaactttt gtcgctggct ttacgagaac agttattgac
     6001 attccaagat tggctattag caatagcaga tatattttca actgaagatc tttattttga
     6061 tgttcgcttt attgaagata gtgatttgac acaagagtca gtcggacgac ttcagatacc
     6121 acagttatta aatgcagatg atcttaaaga taatcgtcaa tcagaaacaa ttgcacgggc
     6181 tttagatatg ttagaagcag tgtctcaatt gaatgccaat tatgaagcag ctattcattt
     6241 gccaacagtt cgaacgccta gccaacttaa ggcaacttac gagcctttat tagaacccat
     6301 tggtgtagat attatagaga aatcttctcg atcgctatct gattttactt tgccacattt
     6361 ttcaaaaaaa gcaaaagttg aagcaagtca tattggatca gctcttcatc agttgatgca
     6421 ggtgctccct ttgtcaaaac cgataaatca acaaacgctt ttagacgctt taagaggaat
     6481 tgatagtaac gaagaggtaa aaacagctct tgatctcaaa aaaatagagt cgttcttttg
     6541 tgatacaagc ctaggccaat tttttcagac ttaccaaaaa cacttgtatc gagaagcgcc
     6601 atttgctatt ttaaaagttg accctattag tcaagaagaa tatgtcctac gtggtattat
     6661 agatgcctac tttttgtttg atgatcatat tgtattagtg gactataaaa ccgataaata
     6721 caagcagccc attgagttaa aaaagcgtta ccaacaacag ttggagttat atgcagaagc
     6781 tctcactcaa acgtataaac ttcctgtgac taagcgctat cttgttttaa tgggaggtgg
     6841 aaagccagaa attgtcgaag tttaaggttg ttgtgacaca aggggatttt gcaaatgata
     6901 atagtagagt tgaggatttt acgaaatact tgaaaagcta ttgacctttg aataataata
     6961 caatataata agttttatta gcgacaaaaa ggaataaata tactatgaat tttaaaaaaa
     7021 taagatttgg ttttttgctt tgcctcctac tttatccttt agcagcctgt aacaagtctg
     7081 aacaacttaa tcaccacgaa agaattaaaa aaacaagaaa attagtcgtt gctgtaagcc
     7141 ctgattatgc tccttttgaa tttaaagctt tagttaatgg aaaagatact attgttggag
     7201 cagatgttca attagctcag gctattgctg atgaattaga cgttgatctt gagctttcac
     7261 caatgagttt tgataatgtt ttgtctagtt tacagactgg taaagctgat cttgctattt
     7321 caggaatctc acatactaaa gaaagagcta aagtatatga tttttcaatt ccttactatc
     7381 aggcagaaaa cgctatagtg atgagagcat ctgatgctaa agtgaccaaa aatattagtg
     7441 acctaaacgg taagaaagta gccgctcaaa aaggtagtat cgaggaaggt ttagttaaaa
     7501 tacaattacc aaaggccaat ctgatttctt tgactgctat gggagaagcc attaatgaac
     7561 taaaagcagg acaagtctat gcagttacct tagaaacacc tgtagctgct ggttttttag
     7621 cccaacataa ggatctggct ttagcaccct ttagcttaaa aaccagtgat ggagatgcca
     7681 aagcagtggc ccttcctaaa aatagtggtg acttaaccaa agccgttaat aaggttattg
     7741 ctaagttaga tgagcaagaa cggtacaagt catttattgc agagacaata gcactaacga
     7801 aaaatactat gaagtaataa ggttaataaa aactttatta gtatccgttg gaaaagtgtt
     7861 tggaataaac aataaaagag gtttgacttt ttttaaaaaa taatgtaata taattgggaa
     7921 cgtgaaaatg ttacaatatc ttgaggaggt gaaacacatg tcaaaaacag tagtacgtaa
     7981 gaatgaatct cttgacgatg ctcttcgtcg cttcaaacgt tctgttacta aagctggtac
     8041 tcttcaagaa tcacgtaaac gtgaattcta cgaaaaacct tctgtaaaac gtaaacgtaa
     8101 atcagaagca gctcgcaaac gtaaaaaatt ctaatggtaa aaaataaaaa cagttctcac
     8161 aattagaact gtttttattt tttatccaga agaagcaagg gagctttttt gatatcaaaa
     8221 aaagcagtta gacatgccta actactttat caaaaatcga tttatttttg agccaacaaa
     8281 tcacggattt ctgtcaataa ttcttcttga gtaggagctg cagcttcttt ttctttttta
     8341 ggcatagctt tttcagcggc ttttacaaca aagaaaagac tggtaccgat gataagaaaa
     8401 ttaataacgg ctcctaaaaa gctaccatat ttaacaccat tccatgacaa ttgagtgatg
     8461 ttttcaacat ttgcagcttt cagagctggg tttaaaataa gcggtgtgat aatatcgttc
     8521 acaaaagaag tgacaatagc accaaaagct cccccgatga taactgctac agcaagttca
     8581 ataatgtttc ctctaaacaa aaatgctttt aattctttaa ccattaaata tccccccttt
     8641 taatatctct aagttaagca tagcataatt agtaaacaaa atccaatgga atcacttcag
     8701 tttttaaatt tacaaaaaag agtttcggtg gtataataaa acgtaaaact aaaatgggat
     8761 ttttatgggg aggtgacgat ttggcaattg acaaagaaat gatttcccaa gtaaaaaata
     8821 gcgttaatat tgtcgatgtc attggagaag tggtcaaact ttcccgatca gggcggcatt
     8881 atctcgggct ttgcccattt cataaggaaa agacaccctc ttttaatgtt gttgaagaca
     8941 gacaattttt tcactgcttt ggctgtggaa aatcagggga tgtttttaaa tttattgagg
     9001 aataccgcca agtccccttc ttagaaagtg ttcagattat tgccgataag actggtatgt
     9061 cgcttaatat accgccaagt caggcagtac ttgctagcca acacaagcac cctaatcacg
     9121 ctttgatgac acttcatgag gatgctgcta aattttacca tgcagttttg atgaccacta
     9181 ccattggtca agaagctagg aagtaccttt accagagagg cttggatgac caattaattg
     9241 agcatttcaa tattggttta gccccagatg agtcagatta tctttatcaa gctctttcta
     9301 aaaaatacga ggaaggtcaa ttggttgctt caggattgtt taacttgtcc gatcaatcta
     9361 ataccattta cgacgccttt cgaaatcgta tcatgtttcc cttatcagat gaccgagggc
     9421 atattattgc cttttcagga cgtatctgga cggcagctga tacagaaaag agacaggcca
     9481 agtataaaaa ttcaagagga acagttcttt ttaacaaatc ttatgaattg tatcatctgg
     9541 acaaggcaag gcctgttatt gccaaaaccc atgaagtatt tctaatggaa gggtttatgg
     9601 acgtgattgc cgcttaccgt tccggctatg aaaatgccgt tgcttcaatg gggacggcat
     9661 tgactcaaga acatgtcaat caccttaagc aagtcactaa aaaagttgtt ttgatttatg
     9721 atggtgacga tgctggacaa catgctattg caaaatcact agaattgctt aaagattttg
     9781 ttgtcgaaat tgtcagaatg cccaataaaa tggatcctga cgaatttgta caacggcatt
     9841 ccccagaagc atttgcagat ttgcttaagc agtcacggat cagtagtgtt gaatttttta
     9901 ttgattacct aaaacctact aatgtagaca atttgcaatc acaaattgtt tatgtggaga
     9961 aaatggcacc attgattgct caatcaccat ccatcacagc tcaacattcg tatattaaca
    10021 agattgctga tttgttgcca aactttgact attttcaagt agaacaatca gtaaatgcat
    10081 taaggattca agataggcaa aagcgtcaag gtcaaatagc tcaagccgtc agcaatcttg
    10141 tgaccttacc aatgccaaaa agtttgacag ctattgctaa gacagaaagt catctcatgc
    10201 atcggctctt acatcatgac tatttattaa atgaatttcg acatcgtgat gatttttatt
    10261 ttgatacctc taccttagaa ttactttatc aacggctgaa gcaacaagga catattacat
    10321 cttatgattt gtcagagatg tcagaggaag ttaatcgtgc ttattacaat gttttagaag
    10381 aaaaccttcc caaagaagta gctcttggtg agattgatga tattttatcc aaacgtgcca
    10441 aacttttagc agagcgcgat cttcacaaac aagggaaaaa agttagagaa tctagtaaca
    10501 aaggcgatca tcaagcggct ctagaagtac tagaacattt tattgcgcag aaacgaaaaa
    10561 tggaatagag gaaattatga caaaacaaaa agaaataaca acttttaacg ttcaagttgc
    10621 ggagtttatt cgccatcaca aaaaagaagg aacagcgatt gatgatgacg tgaccgaaaa
    10681 acttgtcatt ccatttgctt tggatgctga tcagattgat gatttacttg agcggttaac
    10741 agatggtggt atctcgatta cggataaaga aggtaaccca tcatcaaaat acattgttga
    10801 agaaccaaaa ccagaagaat taactgatga agaattaatt ggtagtaatt cagctaaagt
    10861 aaacgaccct gtccgcatgt acctcaaaga aattggtgtg gtaccgcttt taacaagtga
    10921 agaggaaaaa gaattggctg ttgcggttgc caagggagat ttaatggcta aacaacgttt
    10981 agcggaagca aaccttcgtc ttgttgtctc aattgcaaaa cgttatgttg gacgtggaat
    11041 gcaatttctt gatttaattc aagaaggtaa catgggactc atgaaagctg ttgataaatt
    11101 tgattattca aaaggattca aattctcaac ttatgcaaca tggtggattc gtcaagctat
    11161 aacacgcgca attgcagatc aagcacgtac gattcgtatc cctgttcata tggttgaaac
    11221 gattaacaaa ttagtccgtg aacaacgtaa ccttcttcaa gaacttggtc aagatccaac
    11281 gccagaacaa atcgcagaac gtatggaaat gactccagac aaggttcgtg aaattctaaa
    11341 aattgctcaa gaacctgttt ctttagaaac accaattggg gaagaagatg atagtcactt
    11401 aggtgatttt atcgaagatg aagttattga aaatccagta gattatacga cgcgtgttgt
    11461 tcttcgtgag caattggatg aagttttaga tacgcttact gaccgtgaag agaacgttct
    11521 tcgcctacgc tttggccttg acgatggtaa aatgcgtacg ttagaggacg taggtaaagt
    11581 ttttaacgtt actcgtgagc gcattcgaca gattgaagct aaagccctta gaaaacttcg
    11641 ccatcctagt cgtagtaaac aattaagaga ctttatagag gactaaaatc gtccagtgga
    11701 cgattttagg tcgttccttt gaaataagaa aggagcgaaa atcccaagtg gcacttatca
    11761 gcggtacacc tacaaattag aaatcggacc gaatgtggtg ggcattttta aggttggact
    11821 taatatctta aacaagccca gagggcaatt tcctctaaat gggcaaagct ttagtggttt
    11881 ttttacttat ctacgacata ttcaaaaaat gaaaggaaag ccatgtctga tacaccaaaa
    11941 tatacacaag atcaggtgat agctatcaag aatagaattc ttgaagcttt agaaactgtt
    12001 attgatcccg agctaggtat tgatgttgtt aatctaggct tgatttatga aattcggttt
    12061 aatgataacg gttatacaga gattgatatg acactcacaa caatgggttg tcctttggca
    12121 gacttgttga cagattacat ccatgatgcc ctgcaagatg tgccagaggt cactaagact
    12181 gaggtcaaat tagtctggta ccctgcttgg acggttgata aaatgagccg ctatgctagg
    12241 attgcgctgg gtattcgcta atcattgata gtaaagggat gaaatattcc cttttttgat
    12301 gtagaataaa aggaaataca ggtgaaagcc tttggttaat gttagagaac actaagatac
    12361 tgagaaaagt gttctaccta tggcaaaaag gagaactgat gattttaatt acaggaagca
    12421 atggtcaatt agggacagaa cttcgatact tattagatga acgaggtgtt gattatgtag
    12481 ccgttgatgt cgcagaaatg gacatcacaa atgaagacaa agtcgaagct gtttttgcgc
    12541 aggtcaagcc aacattggtc tatcattgtg ctgcttatac ggcagttgat gcagcagaag
    12601 acgaaggaaa agccttgaat gaggctatta atgtaacagg ctcagaaaat attgccaagg
    12661 cttgtggaaa atatggggct acccttgttt acatttcaac agactacgta tttgatggca
    12721 ataaaccagt cggtcaagaa tgggtagaaa cagatcgtcc agaccctaag acagaatatg
    12781 gccgtacaaa acgtttagga gaactagctg ttgaacgata cgcagagtat ttttatatta
    12841 tccgtactgc ttgggtattt ggaaattatg gtaaaaactt tgtctttacc atggagcagt
    12901 tagcggaaaa tcactcccgt ttgactgttg tcaatgacca acacggtcgg ccaacgtgga
    12961 caagaacctt ggcagaattc atgtgttatt tgacagagaa tcaaaaagcc tttggttact
    13021 atcacttgtc aaatgatgct aaggaagaca ccacttggta tgattttgcc aaagaaatct
    13081 taaaagacaa ggctgttgaa gtggtgccag ttgattcatc agctttccca gcaaaagcca
    13141 aacgtccttt aaattcaacc atgaatcttg ataaggcaaa agcaacaggg tttgttattc
    13201 caacatggca agaagccttg aaggcatttt accaacaagg actgaaaaag taagtattct
    13261 aaaaagagtt ggccttctaa ggccaactct ttttcatggg tttaaggtcg cattagcctt
    13321 ctaattgtgg tataatatca ctgattatat tttagaatgg ggtagtatgc aatgcaggat
    13381 gtttttatca ttggtagcag agggttacca gcgaaatacg gtggctttga aacctttgtc
    13441 gaagagttga ttagtcatca atcatctaaa aacattcgtt atcacgttgc ttgtttaagc
    13501 gatacgaagc ataaggttca ttttgattat aagggggcag attgctttta ccttaatccc
    13561 ccaaaacttg gtcctgctag agttattgct tatgatatga tggcaattac ctatgccctg
    13621 tcttatagcg accaacacca gattcagaac cctatttttt atgtgttggg caatactgta
    13681 ggcgctttta ttgcgccatt tgtgaagcag attcacaatc gaggtggacg cttttttatc
    13741 aatccagacg ggttagagtg gaaacggtct aaatggtcaa aaccagtgca ggcctacctg
    13801 aagttttccg aaaagcaaat gactagacag gctgatttgg tcatttcaga taatattggc
    13861 attgaccgct accttaaaca ggtttatcct tggtctaaaa catgttttat tgcttatgga
    13921 acgcagacac aaccttcacg tttgacaaca gcagatagca aggtcagagc ttattttcaa
    13981 acctttgata ttagagaaaa ggattactat ctcattttag gacgctttgt tcctgaaaat
    14041 aattacgaag ctgctattaa agaatttatg gcttcctcaa ctaagcgtga tttagtgatt
    14101 atttgtaatc atgaaggcaa tgcttacttt aagcaattac ttgctgagac agagtgtgat
    14161 aaagacccac gcattaaatt tgttggtacc ctttatgata aagaactatt agcctacatt
    14221 cgagaacagg cttatgccta tatccatggt catgaggtag gagggactaa tccaggcctt
    14281 ctagaagcac tagcccatac caatcttaat ttggttttag gagttgattt taaccagtcg
    14341 gtggctaagt ctgctgcgct gtattggtcc aagcaaaaag ggcaattagc agagctgatt
    14401 aaccaagttg atgcaggttt tgatagtgat catctgggca aagaagccaa agctattatt
    14461 caagaacatt acacttggga aaaaattgta ggggagtacg aggctttatt tttaaatgaa
    14521 cattaatatt ttactatcca cctacaatgg agaacgcttc ttagcagaac aaattcaaag
    14581 tatccaaagg caaacagtta acgactggac cttattgatt agagatgatg gttcaactga
    14641 tggcacccag gatattattc gcacatttgt caaggaagac aaacgaattc agtggatcaa
    14701 tgaggggcag acagaaaatc tgggagttat taagaatttt tacaccctct taaagcacca
    14761 aaaagcagat gtctattttt tcagtgacca agatgatata tggttagaca ataaactgga
    14821 agtgacctta ttggaggctc aaaaacatga aatggcagct cctttattgg tttatacaga
    14881 cctcaaagtg gtaacccaac atttagctat ttgccatgac agtatgatta agacccaatc
    14941 tggtcatgca aacacaagcc tacttcaaga attaaccgaa aataccgtaa caggcggcac
    15001 aatgatgatt actcatgctc tggctgagga atggaccact tgtgacggtt tattgatgca
    15061 tgactggtat ttagctttac tagcttctgc tactgggaaa ttagtttacc ttgatattcc
    15121 aacagaatta taccgtcagc acgatgctaa cgtgttggga gctagaactt ggtctaaacg
    15181 catgaaaaat tggttaaccc cccatcattt agtcaacaaa tattggtggt tgattacttc
    15241 aagccaaaaa caggctcaat tactattaga tttaccatta aaaccaaatg atcatgaatt
    15301 ggtaacggcc tatgtttctt tattggatat gccttttacc aaacgcttag ctaccttgaa
    15361 aaggtacggt tttagaaaaa atcgcatctt tcacaccttt atttttcgta gtttagttgt
    15421 taccttattt ggttacagga gaaagtaaga atgaattttt taacaaagaa aaaccgtatt
    15481 ttactgagag aaatggtaaa aacggatttt aaattacgct atcaagggag cgcaattggc
    15541 tatctatggt ctatcttaaa accgcttatg atgtttacga ttatgtactt ggtatttatt
    15601 cgttttcttc gcctgggtgg aaatgtacct cattttccag tagcgctttt attggcaaat
    15661 gtcatctggt cttttttttc agaagcaact agcatgggaa tggtatctat tgtatctcgg
    15721 ggagacttgt tgcgaaaatt gaacttttct aagcacatca ttgttttttc ggcagtgtta
    15781 ggagctttaa ttaattttct tattaatttg gttgttgttt taatttttgc gttgataaat
    15841 ggtgtgacta tatcagggta tgcttatctc tctctttttc tttttataga attagttgtt
    15901 ttagtgcttg gaattgcatt gttattgtcg aatgtctttg tttattatcg tgacttagct
    15961 caagtctggg aagtactatt acaagcaggt atgtatgcca ctccaatcat ttatccgatc
    16021 acttttgttt tagatagcca ccctttggcg gcaaagttgt tgatgctaaa tccagtagca
    16081 caaatgattc aagattttcg ttatttattg attgacaggg ccaacgtaac gatttggcag
    16141 atgtcaacca attggtttta cattgttatt ccatatttag taccatttgt tatattattt
    16201 attggcatct ttgtctttaa gaaaaatgcc gatagatttg cggagattat ttaatgatta
    16261 atagagaaat tgcagtaaaa gtacagcatg ttagtaaaac atttaaactg cctacagaag
    16321 caactaaaag ttttcgcacg actctggtta atcgcctaag agggattaaa ggatttactg
    16381 aacaacatgt gctaaaagat attaactttg atgtttataa aggcgatttt tttgggattg
    16441 ttgggcgtaa cggctcggga aaatcaacgc tccttaaaat tatttcccag atctatgttc
    16501 cagaaaaagg gcaggttaca gtagatggga agatggtttc ttttatagag cttggagtgg
    16561 gattcaatcc agaattaaca ggacgagaaa acgtctatat gaacggcgcc atgctgggat
    16621 ttaccaaaga cgaagttgat gatatgtaca atgatattgt tgattttgca gagttgcatc
    16681 attttatgaa tcaaaaatta aaaaattatt cttctggcat gcaggtacgt ttagcatttt
    16741 cagtggctat taaagcccaa ggtgacgttc ttattttaga tgaggtgctt gctgtaggag
    16801 atgaagcttt tcagcgaaaa tgtaatgatt attttatgga aagaaaagac agtggtaaga
    16861 cgactatttt agtgacacat gatatgggag ctgttaagaa gtattgtaac cgtgcagttc
    16921 ttattgaaga tggtcttgtt aaagcatatg gagaaccatt tgatgttgct aatcagtata
    16981 gtgtagataa tacagagaca gctgaggatg caatgaatgc tgaaaaaata tctgtatctg
    17041 atattgccaa agatttgaaa gtgtcattaa tctcaaatcc aagaataaca ccaaatgaca
    17101 caatcacatt tgaagtttct tatgaagttt taaaagatga ttttacctac attgcctttt
    17161 ctttaacgga tattgataga aacatttggg tttacaacga caattcttta gattatccaa
    17221 cacaaggtat aggtagaaaa tgcatttcct accaatgtca actatctcaa cttaatgata
    17281 taaaactaaa attagaagta actgtccgag ataagaacgg tcagatgcta ctcttttcaa
    17341 cagcagaaca atcaccccag atagtgattc aaagaaacga tattgatcaa gatgatctgt
    17401 cagctctaga ttcagcaagt ggcttgtatc aacgtaatgg gaagtgggtt tttcattaat
    17461 gagtaatagc tagaagggaa tttatgtata aagtttcaat tatttgcacc aattataaca
    17521 aagctccttg gatatctgat gcacttgaca gttttttaag ccaagtgaca gattttgagg
    17581 ttgaaattat tgttattgat gatgcttcta cagatgactc acgagagatt ttaaagagtt
    17641 atcaaaaaaa gtcttcagga aaaattaaat tactctttaa cgaaactaat attggaataa
    17701 caaagacttg gataaaagca tgcctttatg caaaaggcaa atatattgct agatgtgatg
    17761 gtgatgatta ctggacggat agttttaaac tccaaaaaca agttgatgtc ttagaagctt
    17821 ccaaacggtc acgatggtgt aatactgatt ttgactttgt aaatagtcaa ggcgacttat
    17881 tatatgctaa tgctttttca tctggtcata cacctttgac agatacttac gaaaaagttt
    17941 tagccttaaa agggatgacg atggcatcga catggttagt tgatgctgat ttaatgagac
    18001 aagtaaacca aaaaatcaat gtagatacac cagacgatac ttttgatatt caactagagt
    18061 tatttcaact gactcaactg acctatatta aagactcaac gacgatttat cgcatgacaa
    18121 ccgattctga ttcaagacct actgatacac caaaaatgat tcatcgtatt caaaaactac
    18181 ttgatactca gttaaattac ttaaaaaagt ataatcaggt agatacaaaa gaagtgtcta
    18241 aactattgtt acaacaagat gctaagcaag aaatacgaat tcatgagttg agttgcttta
    18301 ttcaagaatt acaacaaact atcgtagata aaacaaagca gcaagaaaca cgtgaagtgg
    18361 agttgcaaaa tgtcatagaa gaacaaaaaa atcaactatc tgaattaaga caacaatacc
    18421 atgccattat taattcacgt caatggaaat acacgtctaa gctcattgct tttattagga
    18481 gaaaaaaatg aatcgtattt tattatatgt tcacttcaac aaatacaata aaataagtgc
    18541 acatgtttac tatcaattgg aacaaatgag atcactgttt tctaagattg tttttatctc
    18601 aaatagtaaa gtgagtcacg aagatttaaa acgtctcaaa aatcactgtc ttattgatga
    18661 gtttttgcaa cgcaaaaata aaggttttga tttttctgca tggcacgatg gcttgattac
    18721 tatgggattt gacaaattgg aagagtttga ctcattgacg attatgaacg atacttgttt
    18781 tggtcctatt tgggagatgg ctccttattt tgaaaatttt gaagaaaaag agacagttga
    18841 cttttgggga attactaata atagaggtac aaaagctttt aaagaacatg tccaaagtta
    18901 ttttatgacg tttaaaaatc aagtcattca aaacaaagtt tttcaacaat tttggcaatc
    18961 gataatagaa tatgaaaacg ttcaagaagt gattcaacat tatgaaacgc aattaacatc
    19021 cattctctta aatgaaggct ttagttatca gacggtcttt gatactagaa aagctgagtc
    19081 gtcattcatg ccacatccgg atttttcata ttataatcca acagcaattt taaaacacca
    19141 tgtgcctttt ataaaagtaa aagctattga tgctaaccag catatcgctc cttacttact
    19201 gaatctgata cgagaaacaa ccaattatcc tatagatctt attgtttcac atatgtcgca
    19261 aatctctttg ccagatgcta agtacctttt atctcaaaaa tacctaaact gccaacggtt
    19321 agcaaaacaa acttgtcaaa aggtagctgt tcatttacat gttttttacg ttgatttgct
    19381 agatgaattt ttaacagctt tcgaagactg gaacttccat tatgatcttt ttattacaac
    19441 agatagtgat atcaaaagaa aagagatcaa agaaatactt caaagaaaag gtaaaactgc
    19501 tgatatacgc gttacgggaa atagaggaag agatatttat ccaatgttat tactaaaaga
    19561 taaactttct caatatgatt atattggtca tttccatacg aaaaaatcaa aagaagctga
    19621 tttttgggca ggagaatctt ggcgaaaaga attgattgat atgctcgtga aaccagcaga
    19681 tagtattctt agcgcttttg agacagatga tattggtatt ataatcgcag atattccaag
    19741 tttttttaga tttaataaga ttgtcaatgc ttggaatgag catttaatcg ctcaagaaat
    19801 gatgtctttg tggagaaaaa tggatgttaa aaaacaaatt gattttcaag ctatggatac
    19861 atttgttatg agttatggaa catttgtatg gtttaaatac gatgctctaa aatcactttt
    19921 tgatttagaa ttaactcaaa atgatattcc aagtgaacct ttaccacaaa actctatatt
    19981 acatgcgatt gagcggttac ttgtctatat agcgtggggg aattcttatg attttaggat
    20041 tgttaaaaat ccctatgagt taacaccttt tattgacaat aaactgttaa atttacgtga
    20101 agatgaagga gctcatacct acgttaactt taatcaaatg ggcggtatca aaggagcatt
    20161 aaaatatatt attgttggtc ccgctaaagc aatgaagtat atattcttgc gtttaatgga
    20221 gaaacttaaa tgattaaaga cacattttta aaaaccaatt ggttaaatat tagtcaccat
    20281 attatccttc ttgttttcgg tttttatttc agtttttaca gtttggcgaa agaactagta
    20341 agctccacgg cacaaccggt aaactattat actcatttac taaatgtttc ttttgtggga
    20401 tatattatat cactgattgg attatcttat tatttgagtc gccaagttag tcgacagttg
    20461 tttttgaaaa ctagttttat tgtgatatct tatctaattg tcagctattg ggtacaaata
    20521 acacagcacc tgaatgataa acggtttgat atctggtcat taactaaaaa tcaattttat
    20581 caatttcaag ctctaccttc tttactcatt attttagtga tggccacttt aataaaaata
    20641 ttggtagcat attttgcaat agaaaaagat agatttgggc tattaggcta tcaaggtaat
    20701 actttttctg tagctctgat tttagcagtt gtgccaatta atgacataca tctgttaaaa
    20761 ctaataagtt ctcgattttc tgaattagta acagcaggta atagccaaat tgcactgtta
    20821 aaaataagtg gactgttgat agttttactt gtcatatttg caacaatcat atacgtggtt
    20881 ttaaatgctc taaaacacct taactcaaat aaatcttcat tttcagtagc agctactact
    20941 agtttgtttt tagcattagt ttttaactat acgttccagt atggcgtaaa aggtgatgaa
    21001 gcattgctag gatattatgt tttccctgga gctactcttt ttcagatagt agctattaca
    21061 ctagttgctc ttttagcata cgtgataacg aatagatatt ggccaactac cttctttttg
    21121 cttattctgg gaacaattat ttctgttgtt aatgatttaa aagaatcaat gagaagcgag
    21181 ccgttattag taactgattt tgtttggtta caagaattag gtttagtgac aagctttgtt
    21241 aaaaaatcgg tgattgtaga aatggttgta ggacttgcta tttgtattgt ggtggcttgg
    21301 tatctacatg gccgagtttt agcagggaaa ttatttatga gccctgtcaa acgggcaagt
    21361 gctgtattag gtttatttat tgtatcttgt agtatgttaa taccattttc ttatgaaaaa
    21421 gaaggtaaaa tattatctgg tcttccgatt atttcggctt taaataatga taatgatata
    21481 aactggttag gtttttcaac aaatgctagg tacaaatctt tagcatatgt ttggacaaga
    21541 caggtgacca agaaaataat ggaaaaaccg acaaattata gtcaagaaac aatagcgagt
    21601 atcgctcaga agtaccaaaa attagcagaa gatattaata aagacagaaa aaataatatt
    21661 actgaccaaa cggttattta tcttttaagt gaaagcttgt cagatcctga tagagtatca
    21721 aatgttactg ttagccacga tgttttacct aatatcaagg caatcaaaaa tagcacaact
    21781 gcgggactca tgcagtcaga ctcctacggg ggtggaacgg ctaacatgga gtttcaaacg
    21841 ttaacaagct taccttttta taatttttct tcttcagtat ctgttcttta ttcagaagtc
    21901 tttcctaaaa tggccaaacc tcatacgatt agtgagtttt accaaggaaa aaatcgtatt
    21961 gcgatgcatc ctgctagtgc taacaatttt aatagaaaaa cagtttatag taatttaggt
    22021 ttttccaaat tcttagctct atcgggttct aaggataagt ttaagaacat tgaaaatgtc
    22081 ggt
//
LOCUS       DAUCXI010000032        19852 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.032, whole genome shotgun sequence.
ACCESSION   DAUCXI010000032 DAUCXI010000000
VERSION     DAUCXI010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19852
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.032"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            188..1681
                     /gene="malQ"
                     /locus_tag="VGY43_001283"
     CDS             188..1681
                     /gene="malQ"
                     /locus_tag="VGY43_001283"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEQ4302464.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEATDLCDITFGTNPEAVDYA
                     QLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKEYFNNKALQDW
                     DDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSALKTYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNRWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            1716..3980
                     /gene="glgP"
                     /locus_tag="VGY43_001284"
     CDS             1716..3980
                     /gene="glgP"
                     /locus_tag="VGY43_001284"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEQ4302465.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSIASLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(4237..4857)
                     /locus_tag="VGY43_001285"
     CDS             complement(4237..4857)
                     /locus_tag="VGY43_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEQ4302466.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPNQHDPKTAGEVTIDAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(5159..5506)
                     /gene="ssrA"
                     /locus_tag="VGY43_001286"
     tmRNA           complement(5159..5506)
                     /gene="ssrA"
                     /locus_tag="VGY43_001286"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            5598..6212
                     /locus_tag="VGY43_001287"
     CDS             5598..6212
                     /locus_tag="VGY43_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEQ4302467.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH"
     gene            complement(6339..7124)
                     /locus_tag="VGY43_001288"
     CDS             complement(6339..7124)
                     /locus_tag="VGY43_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302468.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNVNELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHNHIFNIN
                     TSADSFPFTEQKTTYLLILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(7134..7832)
                     /locus_tag="VGY43_001289"
     CDS             complement(7134..7832)
                     /locus_tag="VGY43_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302469.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            complement(7832..8203)
                     /locus_tag="VGY43_001290"
     CDS             complement(7832..8203)
                     /locus_tag="VGY43_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ4302470.1"
                     /translation="MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            8388..11498
                     /locus_tag="VGY43_001291"
     CDS             8388..11498
                     /locus_tag="VGY43_001291"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEQ4302471.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELTDCQQLTTFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDTLTNHLPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQIYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDAKDYSATEKYSLEQEI
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            11578..12591
                     /gene="pfkA"
                     /locus_tag="VGY43_001292"
     CDS             11578..12591
                     /gene="pfkA"
                     /locus_tag="VGY43_001292"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEQ4302472.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            12654..14156
                     /gene="pyk"
                     /locus_tag="VGY43_001293"
     CDS             12654..14156
                     /gene="pyk"
                     /locus_tag="VGY43_001293"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEQ4302473.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            14374..14931
                     /gene="lepB"
                     /locus_tag="VGY43_001294"
     CDS             14374..14931
                     /gene="lepB"
                     /locus_tag="VGY43_001294"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEQ4302474.1"
                     /translation="MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKS
                     GDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            15107..16921
                     /gene="glmS"
                     /locus_tag="VGY43_001295"
     CDS             15107..16921
                     /gene="glmS"
                     /locus_tag="VGY43_001295"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEQ4302475.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSRESTYTMLIHAG
                     PEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKD
                     LVAEKVQALLTTTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            17117..17452
                     /locus_tag="VGY43_001296"
     CDS             17117..17452
                     /locus_tag="VGY43_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEQ4302476.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVVKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            17559..18200
                     /locus_tag="VGY43_001297"
     CDS             17559..18200
                     /locus_tag="VGY43_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEQ4302477.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            18210..18839
                     /locus_tag="VGY43_001298"
     CDS             18210..18839
                     /locus_tag="VGY43_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302478.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQKADAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            18855..19691
                     /locus_tag="VGY43_001299"
     CDS             18855..19691
                     /locus_tag="VGY43_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEQ4302479.1"
                     /translation="MIIKKRTVAILAIASSFFLVGCQATKSLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQDKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     SLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANI
                     KS"
BASE COUNT         6301 a         3291 c         4006 g         6254 t
ORIGIN      
        1 gaatcttagt cagactattt ttgttccttt tagtttaaaa caaagagaaa gcgtccgtga
       61 tattagtcat taagaacaaa aaaagtagca tttttaagga atgttacttt ttttaggaaa
      121 ctggttgact tacgcaagcg cttgcgttat aatctcatca tgaatagatt tcacaaggag
      181 aaaaatcatg aacaaacgtg caagcggtat cttaatgcat attagttccc tgcctgggaa
      241 atttgggata ggcacttttg gaaaatcagc ttttgaattt gttgattttc tagcagagac
      301 gaaacaaacc tattggcaaa ttctgccttt aacaacgacg agttttggag attctcctta
      361 tcagtcattt tcagctattg ctgggaacac acatttcatt gattttgaat tgctagtaga
      421 tgatgaactt ttagaagcaa cagatttgtg tgatattaca ttcggcacaa atcctgaagc
      481 agtagactat gctcagcttt ttcaagttag gcgtccactt ttagaaaaag cagtgagagc
      541 ttttgttgct gaacaagaaa atgtgtgtaa attagaagct tttgaaacag cttctagctg
      601 gttaactgat tttgctgaat ttatggcttt aaaagaatat tttaacaata aagccttaca
      661 agattgggac gacgaaactg tcattaaacg ccaagaagac tcacttaata attaccgtga
      721 gttgcttgca aaaaagatta cctatcataa agtctgtcaa tacttctttt accaacaatg
      781 gtcagccttg aaaacttacg ctaaccataa agggatagaa attattggtg atatgcctat
      841 ttatgtttct gcggacagtg tagaagtttg gacgatgcct gagctattta aagtagatag
      901 tgataaaaag ccattgttta ttgcaggtgt accagcagat ggctttagtg aagatggtca
      961 gctgtgggga aatccaacct acaattggtc tgctcatgaa aagtctaatt ttgcatggtg
     1021 gatttatcgt attcaagaaa gtttcaaact atatgatcag ctaagaatcg atcattttaa
     1081 aggcttctca gatttttggg aaattcctgc tggtgataaa actgctagaa atggccattg
     1141 ggcctcagcc ccaggtatag cgttattttc tgcggttcgt gaggccttag gagagcttcc
     1201 tatcatcgca gaaaaccttg gttatattga tgaaaaagca gagcagctat tagcatcaac
     1261 aggctttcct ggcatgaaga tattagaatt tggtttattt gatataacga gtcaaagtat
     1321 agatttacca cattactatg accgtaattg tgtcgcttac acagggactc atgataacga
     1381 ggtggttaac agatggtatg acaatcttag tgaagaacaa gtacactttg taaataacta
     1441 tcttcacaaa catgcagatg aaagtattac aaaagccatg ctaagaacaa tctttgcttc
     1501 tgtttgtgat acagccattc tttgcatcca agatttatta gataaagatg gtaagagtcg
     1561 tatgaatatg ccaaatacaa ttggaggtaa ttggcaatgg cgtatgcttg acggtgaatt
     1621 gaaccaagat cacaaagatt accttattta tttaacagat ctttatggtc gcgcaagata
     1681 atatttaaat gttacattat tgaaaagagg aagacatgac acgctttaca gaatatgttg
     1741 aaactaaact aggaaaatca cttacgcaag ccagcaatga agagatttat ctatcattat
     1801 taaactttgt caaagaagaa gctagccaca aggctaaaaa ttctgctaaa cgcaaagttt
     1861 actatatctc agcagagttt ttgattggta aattactatc aaacaacctg attaacctag
     1921 gaatttacaa agacatcaaa gaagaattgg cagctgctgg caaatctatc gcagaagtcg
     1981 aagatgttga attagaacca tcactaggta atggtggttt agggcgtttg gcatcatgtt
     2041 tcattgattc tattgcatct cttgggatta atggtgaagg ggttggttta aactatcatt
     2101 gtgggttgtt taagcaagtc ttcaaacaca atgagcaaga agctgaacca aactactgga
     2161 ttgaagacca gtcatggttg gttcctacaa acatttcgta tgatgtgcct tttaagaact
     2221 tcaccttgaa atctcgtctt gatcgtattg atgttttggg ttacaaacgc gacactaaaa
     2281 actaccttaa cttgtttgat atcgagggcg ttgattacgg gttaatcaaa gacggtattt
     2341 catttgataa aacgcaaatt gctaaaaact tgaccttgtt cctctaccca gacgattctg
     2401 acaaaaatgg ggaattgctc cgtatttacc aacagtactt tatggtgtca aatgcagcgc
     2461 aattaatcat tgatgaagct atcgaacgtg gttcaaacct tcatgacctt gcagactacg
     2521 cttacgtgca aatcaatgac actcacccgt caatggtcat cccagaatta attcgtctct
     2581 tgactgaaaa acatggcttt gactttgatg aagcggtagc tgttgtgaaa aatatggttg
     2641 gttacactaa ccacactatt cttgcagaag cccttgaaaa atggccaact gcttacttaa
     2701 acgaagtagt gccacacttg gtaaccatca ttgaaaaatt ggatgctctt gttcgttcag
     2761 aagtgtctga tccagctgtt caaattattg acgaatcagg tcgtgtgcac atggcccata
     2821 tggatattca ttttgcaaca agtgtcaatg gggtagcagc actccacaca gaaatcttga
     2881 aaaacagcga attaaaagct ttctatgacc tttacccaga aaaattcaac aacaaaacca
     2941 acgggattac tttccgtcgt tggctagaat ttgctaacca agacttggct gattacatta
     3001 aagaacttat tggcgatgag tacttgactg acgcaacaaa attagaaaaa ttgatggcct
     3061 ttgcagatga caaagctgtt catgctaaat tggctgaaat caaattcaac aacaaattag
     3121 ctcttaaacg ttaccttaaa gacaataaag acattgagct tgatgaacat tctattattg
     3181 atacccaaat caaacgtttc cacgagtaca aacgtcaaca gatgaatgct ctttacgtga
     3241 ttcacaaata tttggaaatt aaaaaaggca accttccaaa acgtaaaatc actgttatct
     3301 ttggaggtaa agcagcgcct gcttacatca ttgctcaaga catcattcac ttgatccttt
     3361 gcttgtctga attgattaac aatgaccctg aagtaagccc ataccttaat gtgcatctag
     3421 ttgaaaatta caacgtgaca gtagcagagc acttgattcc agcaactgat atttctgagc
     3481 aaatttcact agcatccaaa gaagcttctg gaactggtaa tatgaaattc atgcttaacg
     3541 gtgctttaac acttggtaca atggacggtg ctaacgtaga aatcgctgag cttgcaggca
     3601 tggagaatat ctataccttt ggtaaagatt ctgacaccat catcaacctt tatgcgactg
     3661 cttcttatgt agcaaaagat tactatgata accaccctgc tattaaagca gcagtgaact
     3721 ttattatcag tccagaattg ctagcatttg gcaacgaaga acgtcttgat cgtctttata
     3781 aagaattgat ttcaaaagac tggttcatga ctttgattga ccttgaagag tacattgaag
     3841 tgaaagaaaa aatgttagca gactatgaag accaagattt atggatgaca aaagtggtcc
     3901 ataacatcgc aaaagctgga ttcttctcat ctgaccgtac cattgagcag tataacgaag
     3961 atatttggca ttcacgataa aaaataataa ttgcaatgtg gggtagcggt accgtaacat
     4021 gcttaaacta aattataaga cagtagtttc tgctgtctta tgattttact tcagacttag
     4081 gttaattatt acattaagcg taaagcaagt ctgtttagcg atctatggag gtaattataa
     4141 gaaactacac taaagttttt tattaaaatg atataaaaag attgatttcg atgtacaccg
     4201 aaatcaatct ttttagcaaa atatattact cattttttat tcttcaagtc ctacctgaga
     4261 catttctgtt aactgattat tttcaaaaac gagagaaata ttagctccgc ttgtatctgt
     4321 ctttaagcca ctaacccaaa tcgcttgcaa agtttgatga tcactagatg acgcttggct
     4381 ataattatca ggttctgtta agatcttttt aacgtcttca taagacattc ctttttgtaa
     4441 ttgttggtat tctttttgcg ataagcctaa ctctcttgca aaggtaaaat tagagatggt
     4501 tttaacaata ctactatttt gataaagatt aacagtgaga gtaacttgat caaactgcca
     4561 agtataagcg tcgattgtta cttcgcctgc tgtttttgga tcatgttggt taggctctcc
     4621 aaagagtgaa ataagttctt caaggcttgt tcctcctgta aatgaggaat caacagtcgc
     4681 aagtttaatt ttttcaaagt tagcgcgttt atcttgatga gcggcttggt gtagtcgggg
     4741 agtaatgatt tctgaatcag acggttgagg ctctttatct ttcgttgttg aacaagctac
     4801 caaaaagcta gtaaaaaaag agatgagaag aagtgttagt aagtgttttt ttgtcatatg
     4861 ttatttccta aactattttt gctgtattat atcataaatt ataaacaaga tatagctatg
     4921 attccccata acgcatgcgc tatggggaat ttagtactat tttgattctt ttttttagat
     4981 attcatgaaa aaaatggtca aaaagctctg atatgacaag gttttgagtg gtattgatgg
     5041 agtatcggta agcgtgatgg tatggctata gggataacgg aaactcatga acaagacaaa
     5101 aagaaaaaac cttgatgtaa caaggtttta gtaagttatg attacttacg gtaagcattg
     5161 atggagctgg tgggagtcga acccacgtcc aaacacctgc caacatattt gtctacgtcc
     5221 ataggttatg tcttcattta acaaactaaa gacacataac tcaagccatt agtttgcgag
     5281 tctatcaatc tcttgtcacg aaactagaca atttcgtaac cgtagcttgc tattttgaga
     5341 cttctaacag gacacaagca atcttgtaga agtcacgcta gctggttttt aggcagctaa
     5401 agcgtaagag tttgtatttt ttgcagttat atttaactgg caatttacat ctgccgatgg
     5461 gacgcaaaac atgcctcata atgcctgtcg aatccgtaac aaccccaaat agataattaa
     5521 ccaatttctt acactaacta ttctatcaaa acttttttta aatagcaaaa ttttacagct
     5581 tatggtatga ttagtctatg acaaaacgta attcaaaagc ctatatatta tggcaaaaaa
     5641 ttatcaaaat tttaggaatt attgcattaa ttggtacttt tttcctcgct ttttggctgt
     5701 atagactagg tatattaaac gatagtaatg ctcttaaaga cttagtgcag cgctatagat
     5761 tatgggggcc gtttgttttt attgtcgtgc agatcataca gattgttttt cctgtgattc
     5821 ctggaggcct tacgacagtt gcaggttttt taatctttgg ccctgtaaca ggttttattt
     5881 ataattatgt aggcatcatt attggcagta tagtcctctt cttgctcgtt aagacttatg
     5941 gtcgtaaatt tatcttactc tttgtaaatg acaaaacatt ttacaagtat gaaaggcgtt
     6001 tggagacacc aggatatgaa aaattattta ttttttgtat ggcatcgcct gtttctccag
     6061 ctgatattat ggttatgatt acgggattga cggacatgtc tttaaagcgc tttgtaacta
     6121 ttcttttaat aactaaacca atttctatta tcggctacag ttatttattt atatttggaa
     6181 aagatgttat atcttggttc ttacagcatt aaggtttggt gttaatttga taaaccgctt
     6241 ctatttgatg gaagacggtt ttttaattta ctatgaacac tgaaaaaaac tttcttttaa
     6301 actatagtgt gtcatagttt aaaagaaagt cttaacgctt actgtaggtt gagtttattt
     6361 ttgataataa aattagtggc gaggtaaaac attatcattt caataaattg ttccaaaata
     6421 agaagataag ttgttttttg ctcagtaaat gggaaactat cggcacttgt attaatatta
     6481 aagatgtgat tgtgaacata tgttgcagca acgctaatca gaataactaa tataaaatat
     6541 gcaataaagg ccatcaagcc tcgccgatta gaaaaaagtt gacctataga aatggaaaga
     6601 taaattaata agatactcgt aaatgttgat aataggacat aggctagtac agttagcata
     6661 ttgatgaaat aatccatctt aaaactatta aagaatcctt ctaatagttc gttgacgtta
     6721 aacattggta caattacaat agcgatagca aatgcaagga tgatagtatt gaaaacactg
     6781 caaataaaag aagctagtag ttttgataaa ataatttgat gcgaattgac gggtaaagtc
     6841 aacgttaagt atccttcccg tccaaaaaca cttttgctaa aacgtttgat aatgataagt
     6901 aatgttgata agagggagcc agcgatcagg gagccaaaag ttaaacctaa tgtcagaggc
     6961 aacatcttat tggttagtac tccaaatagt ccatcactat tgctttgagc aaacagtttt
     7021 atcgtaaatg acaaaatggc agcgatggca ataacgaaag cattaagcgc aaagtaccat
     7081 tttccaatag atctaaattc gtattttaat aattttccaa acatgatatc ctcctaaacc
     7141 ttataagttt ccctaaagag ggaatcaatg gattgctggt attcttgtct tagatcatca
     7201 gcattgccag ataagaaaag tcttccttgt ttcaagaaaa tgacttcgtc aaggataggt
     7261 tcaatgtccg aaatcaagtg ggttgagata ataacagaag cattttcaca ataactatta
     7321 atgatggttt ttaggatgta gtctcttgcg gcagggtcaa ctccaccaat aggttcatca
     7381 agtacataga gtctggcttt acgactcatc acaagaatta attgtacttt ttctttgttt
     7441 cctttggata gagttttgaa gcggtcttca gggtctagtt ctaaatctct tagaaggctt
     7501 gttgctttgg atttgtcaaa gtcgctgtaa aaatcactaa agaactccaa catgtcctta
     7561 attctcatat tttcattgag ataagtagta tctggtaaat aagaaataat tttttttgtc
     7621 tcaacacagg gacggtagcc atcaatgaca atttctcctt tatttggttg taaaaggcca
     7681 ttaatgagtt taattaaagt tgttttacca cttccatttg gacctaataa tccgataatt
     7741 ttaccgttcg ggatagtaat ggttaagtca tcaatagctt ttttttcacg gtaagatttt
     7801 gaaacatgat gtagttgcaa taggtgtgcc attattgtga atcctccttt aaaaagctcg
     7861 tcaaaacagg gataatctca gtgtgactaa atcccatttt tgtcatattg gtgataaatg
     7921 attctaattc actaattgct aactctcgtc ttttacgagc aattaatttt tgatcgtcag
     7981 tcacaaaacg accagcagta cgttgcgaat aaaccattcc ttcccgttca agttctgtaa
     8041 acgctcgttg catggtgtta ggattgacac ctgcgatttc tgcatattca cgaacagttg
     8101 gaagttgatc accactcttg atttcttggc taataatttg catcatgaca tgttgtgcta
     8161 tctgcgcata aataggagat ttttcatcaa atttccaaga catgtggtct cctttctgag
     8221 taatatagat atttgtacta attaaatggt acagaaaaaa aaagggaatg tcaagtttta
     8281 tgccattttt cactctttga gaagtagacg tagattagag agaaaattga agcaagaaaa
     8341 cctttttcat agtataatag ggaacaagat aaccaaagga ggaacttatg tttgctcaac
     8401 ttgatactaa aactgtatac tcatttatgg atagtttaat tgacttaaat cattattttg
     8461 aacgagcaaa gcaatttggt taccacacca taggaatcat ggataaggat aatctttatg
     8521 gtgcttacca ttttattaaa ggttgtcaaa aaaatggact gcagccagtt ttaggtttgg
     8581 aagtagagat tctctatcaa gagcggcagg tgctccttaa cttaatcgcc cagaatacac
     8641 aaggctatca tcagctttta aaaatttcca cggcaaaaat gtctggcaag cttcatatgg
     8701 attacctctg ccaacatttg gaagggatag cggttattat tcctagtaag ggttggagcg
     8761 atacattagt ggtccctttt gactactata tcggtgttga tcagtatact gatttatctc
     8821 atatggattc taagaggcag cttatacccc taaggacagt tcgttatttt gcgcaagatg
     8881 atatggaaac cctgcacatg ttgcatgcca ttcgagataa cctcagtctg gcagagaccc
     8941 ctgtggtaga aagtgatcaa gagttaacag attgtcaaca actaaccacc ttctatcaaa
     9001 cacactgccc tcaagctcta cagaatttag aagacttagt gtcaggaatc tattatgatt
     9061 tcgatacaaa tttaaaattg cctcatttta atagagataa gtctgccaag caagaattgc
     9121 aagagttgac tgaggctggt ttgaaggaaa aaggattgtg gaaagagcct tatcaatcgc
     9181 gcttactgca tgaattggtc attatttctg acatgggctt tgatgattat tttttgattg
     9241 tgtgggattt acttcgcttt ggacgcagta aaggctatta tatgggtatg ggacgtggct
     9301 cggcggcagg tagtctagtg gcttatgctc tgaacattac agggattgat ccagttcaac
     9361 atgatttgct atttgagcgc tttttaaaca aagaacgtta tagcatgcct gatattgata
     9421 tcgatcttcc agatatttac cgttcagaat ttctacggta tgtccgaaat cgttatggta
     9481 gcgaccattc ggcgcaaatt gtgacctttt caacctttgg acctaaacag gctattcgtg
     9541 atgttttcaa acgattcggg gttccagaat acgaactgac caatctcact aaaaaaattg
     9601 gttttaaaga tagcttggct actgtctatg aaaagtcaat ctcttttagg caggttatta
     9661 atagtagaac tgaatttcaa aaggcttttg ccattgccaa gcgtatcgaa ggaaatccaa
     9721 gacaaacgtc cattcatgca gctggtattg tgatgagtga tgataccttg accaatcatc
     9781 ttcctctaaa atcgggcgat gacatgatga tcacccagta tgatgctcat gcggtcgaag
     9841 ctaatggcct gttaaaaatg gattttttgg ggttaagaaa tttgaccttt gttcaaaaaa
     9901 tgcaagagaa ggttgctaaa gactacgggt gtcagattga tattgcagcc attgatttag
     9961 aagacccgca aacgttggca ctttttgcta aaggggatac caagggaatt ttccaatttg
    10021 aacaaaatgg tgctattaat cttttaaaac ggattaagcc acaacgtttt gaagaaattg
    10081 ttgccactac cagtctaaat agaccagggg caagtgacta taccactaat ttcattaaac
    10141 gaagagaagg acaagaaaaa attgatttga ttgatcctgt gattgctccc attttagagc
    10201 caacttacgg tattatgctt tatcaagaac aagttatgca gattgcacag atttatgctg
    10261 gttttacgtt aggcaaggcc gacttgttaa ggcgtgccat gtctaaaaaa aatctacaag
    10321 aaatgcaaaa aatggaagaa gactttattg cttctgctaa gcacctaggg agagctgaag
    10381 aaacagctag aggacttttt aaacggatgg aaaaatttgc aggttatggt tttaaccgca
    10441 gccatgcctt tgcctattca gctttagctt ttcaattggc ttatttcaaa gcccattatc
    10501 cggctgtttt ttacgatatc atgatgaatt attctagcag tgactatatc acagatgctc
    10561 tagaatcaga ttttcaagta gcgcaagtta ccattaatag tattccttac actgataaaa
    10621 ttgaagctag caagatttac atggggctga aaaatattaa ggggttgcca agggattttg
    10681 cttattggat tatcgagcaa agaccattta atagcgtaga ggattttctc actagaactc
    10741 cagaaaaata tcaaaaaaag gttttccttg agcctctgat aaaaataggt ctgtttgatt
    10801 gctttgagcc taaccgtaaa aaaattctgg acaatttgga tggtttactg gtatttgtta
    10861 atgagcttgg ttctcttttt tcagattctt cctttagttg ggtagatgcg aaagattact
    10921 cagcaactga aaaatattct ttggaacagg agatcgttgg ggttggcatg agcaagcatc
    10981 ctttaattga tattgctgag aaaagtaccc aaacttttac tcccatttca cagttagtca
    11041 aagaaagcga agcagtcgta ctgattcaaa tagatagcat taggatcatt agaaccaaaa
    11101 caagtgggca gcaaatggct tttttaagtg tgaatgacac taagaaaaag ctcgatgtca
    11161 cactttttcc acaagagtat gctatttata aagaccaatt aaaagaagga gaattctatt
    11221 acttaaaagg tagaataaaa gaaagagacc atcgactgca gatggtgtgt cagcaagtgc
    11281 aaatggctat tagtcaaaaa tattggttat tagttgaaaa ccatcagttt gattcccaaa
    11341 tttctgagat tttaggtgcc tttccaggaa cgacaccagt tgttattcac tatcaaaaaa
    11401 ataaggaaac aattgcatta actaagattc aggttcatgt aacagagaat ttaaaggaaa
    11461 aacttcgtcc ttttgttctg aaaacggttt ttcgataaaa atggacaatt agtgaagtat
    11521 tttgcaaatg aatgtgctat aataagaccg ttaaattaat taaaggagta ccagaaaatg
    11581 aaacgtattg ctgttttaac cagtggcggc gacgctcctg gtatgaatgc tgctattcgt
    11641 gcagtcgttc gtaaagcaat ttcagaagga atggaagttt atggtatcaa ccgtggctat
    11701 gcaggtatgg ttgatggcga cattttccca ctgggttcaa aagaagttgg tgataaaatc
    11761 tcacgtggtg gaactttctt atactcagct cgttatccag aatttgctca acttgaaggt
    11821 caattggctg gtattgagca acttaaaaaa catggtattg agggtgttgt tgttattggt
    11881 ggggatggtt cttatcatgg cgctatgcgc ttgacagagc acggcttccc agcggtaggt
    11941 atcccaggaa caatcgataa cgatattgcg ggaactgact acactatcgg atttgataca
    12001 gcagttaaca cagcagttga agctattgat aaacttcgtg acacctcatc aagtcacgga
    12061 cgtacttttg tggttgaagt gatgggtcgc aatgcgggtg atattgctct ttgggcaggt
    12121 attgctagtg gtgctgatca aatcattgtt ccagaagaag agtttgatat tgaaaaagtg
    12181 gcatcaacaa tccaatatga ttttgaacac aaaggtaaaa atcaccacat tatcgtctta
    12241 gctgaaggtg ttatgagcgg tgaagctttt gctcaaaaac tgaaagaagc tggcgataag
    12301 agtgaccttc gtgtgacaaa tcttggtcac attcttcgtg ggggttcacc aactgctcgt
    12361 gaccgtgtca ttgcttcttg gatgggttca catgctgttg agctacttaa agaaggcaaa
    12421 ggtggtttgg ctgttggtat tcacaatgaa gaacttgttg aaagcccaat ccttggtact
    12481 gcagaagaag gtgctttgtt cagcttgact gaagaaggca agattattgt taataatcca
    12541 cacaaagctc gtttagactt tgcagctttg aaccgttcat tgtcacaata agtttagtta
    12601 aaattgttaa atcgtcaatt attgacaaaa aaataaggga gtttcagagt aaaatgaata
    12661 aacgcgtaaa aatcgttgca acacttggtc ctgcggttga aatccgtggt ggtaaaaaat
    12721 acggagaaga tggctactgg gctggtcaac ttgatgttga agaatcagca aaaaaaatcg
    12781 ctgaattaat tgaagctggt gcgaatgttt tccgtttcaa tttctcacat ggtgaccaca
    12841 aagaacaagg tgaccgtatg gcaactgttc gccttgcaga agaaattgct cgtcaaaaag
    12901 ttggtttcct tttggatact aaaggtcctg aaatgcgtac ggaattgttt gcagatgatg
    12961 ctaaagaatt cagctatgtc actggagaaa aaatccgtgt agcgactaca caaggtattc
    13021 aatcaactcg cgatgttatt gctttgaacg ttgctggtag ccttgacatc tacgatgaag
    13081 tagaagtagg tcatactatt cttatcgatg atggtaaact cggtttgaaa gtgatcgaca
    13141 aagatatcgc aacacgtcaa tttatcgttg aagtagaaaa cgatggtatt attgctaaac
    13201 aaaaaggtgt taatatccct aacactaaaa ttcctttccc agcacttgcg gaacgcgaca
    13261 atgctgatat ccgttttggt cttgaacaag gacttaactt tattgcaatc tcatttgttc
    13321 gtacagccaa agacgttgag gaagttcgtg aaatctgtcg cgaaactggt aacgatcatg
    13381 tgcaattatt tgctaagatt gaaaaccaac aaggtatcga taatcttgat gaaatcatcg
    13441 aagctgctga tggtatcatg attgcacgtg gcgacatggg tatcgaagta ccatttgaaa
    13501 tggttccagt tttccaaaaa atgattatca ctaaagtgaa tgcagctggt aaagcagtta
    13561 tcacagcaac aaatatgctt gaaacaatga ctgaaaaacc acgtgcgaca cgttctgaag
    13621 tatctgacgt cttcaatgct gttatcgatg gtactgatgc aacaatgctt tcaggagagt
    13681 cagctaacgg taaatacccg gttgaatctg ttcgtacaat ggcgactatt gatcgtaatg
    13741 cacaaactct tcttaacgaa tatggtcgtt tagattcatc tgccttccca cgtaccaata
    13801 aaacagatgt tattgcttca gctgttaaag atgccactca ttcaatggac atcaaacttg
    13861 ttgtgactat tactgagaca ggtaatacag ctcgtgcgat ttctaaattc cgtccagatg
    13921 cggatatctt agctgtaaca tttgatgaaa aagtacaacg tgctttgatg attaactggg
    13981 gtgttattcc tgttcttgct gaaaaacctg catctactga tgacatgttt gaagtagcag
    14041 agcgtgttgc tgtggaggca ggcttagttc aatctgggga taatattgtt attgttgctg
    14101 gtgttccagt tggtactggt ggaacgaata ctatgcgtgt tcgtacagta aaataaatgt
    14161 gttataacta tttacctaaa ggttagaagg caagcttcta accttttttg atatcaaaaa
    14221 tatcatgtta attcactagt gttaatttac tttaatgagt ctaagtttgt attttataca
    14281 gaatgagtaa cgtttattgg tattgatcaa aaattgttta ctttttttct agcttagaac
    14341 atggtataat aagacaatag actaggagtt aatatggtaa agcgagattt tataagaaat
    14401 atattattgt tattaattgt gattattggg gctattttgt tgagaatctt tgttttttca
    14461 acttttaaag tttctccaga aacagctaat acttatttaa agagtggtga tttagtcaca
    14521 atcaaaaaaa atattcagcc caaatataaa gattttgtgg tttatagagt tggaaaaaaa
    14581 gattatgtca gtcgagtcat tgctgttgaa ggcgatagcg tgacttatat ggatgatatt
    14641 ttttacctca ataatatggt agagtcacag gcttaccttg aaaagatgaa agcacattac
    14701 ttgaatcatg caccgtttgg cacattgtat acagatgatt ttacagttgc taccatcaca
    14761 gctgataagt atcaaaaagt tcctaagggg aagtatcttc ttttgaatga taaccggaaa
    14821 aatacgaatg acagtcgtcg atttgggtta ataaatgcct cgcagattaa aggtttagtg
    14881 acctttagag ttttgcctct cagcgatttt ggatttgtag aagtagagta gttgtcaggc
    14941 tactctactt tttttataat tagactatac caattttatg tttgacaaga cattgtggat
    15001 attatatact gtaaacatac tgtttttatc ggtataatta gactatacca attattgaaa
    15061 ttatgagaga aagtagcaag ttaacgaact tgttaaggta attaagatgt gtggaattgt
    15121 tggagttgtt ggaaatcgca atgcaacgga tattttaatg caaggccttg aaaagcttga
    15181 ataccggggt tatgattcag caggaatttt tgtggctaat gccaatcaaa caaacttgat
    15241 taaatcagtg gggcggattg ctgatttgcg tgccaagatt ggcattgatg ttgctggttc
    15301 aacagggatt ggtcacaccc gttgggcaac gcatggccaa tcaacagagg ataatgccca
    15361 tcctcacacg tcacaaactg gacgttttgt acttgttcat aatggtgtga ttgaaaatta
    15421 ccttcacatt aaaacagagt tcctagctgg acatgatttt aaggggcaga cagatactga
    15481 gattgcagta cacttgattg gaaaatttgt ggaagaagac aagttgtcag tactggaagc
    15541 ttttaaaaaa gctttaagca ttattgaagg ttcctatgcc tttgcgttaa tggatagcca
    15601 agcaactgat actatttatg tggctaaaaa caaatctcca ttgttgattg gacttggtga
    15661 aggttacaac atggtttgtt cagatgccat ggccatgatt cgtgaaacca gtgaatttat
    15721 ggaaattcat gataaggagc tagttatttt aaccaaagat aaggtaactg ttacagacta
    15781 cgatggtaaa gagctgatac gagattccta cactgctgaa ttagacttat ctgatattgg
    15841 caaagggact tatcctttct atatgctgaa agaaattgat gagcaaccaa ccgtaatgcg
    15901 tcaattaatt tcaacttatg cagatgaaac tggtaacgta caggttgatc cagctatcat
    15961 tacctctatc caagaggctg accgtcttta tattttagcg gcagggactt cctaccatgc
    16021 tggttttgca acaaaaaata tgcttgagca attgacagat acaccagttg agttgggagt
    16081 ggcttctgag tggggttacc acatgcctct gcttagcaag aaaccaatgt ttattctact
    16141 aagccaatca ggagaaaccg cagatagtcg tcaagtttta gtaaaggcaa atgctatggg
    16201 cattccgagt ttgacagtaa ctaacgttcc aggatcaacc ttatcacgtg aatcaacata
    16261 caccatgttg attcatgctg gacctgaaat tgctgttgca tctacaaaag cttacactgc
    16321 acaaattgct gcccttgcct ttttggctaa ggcagttggt gaggcaaatg gtaagcaaga
    16381 agctcttgac tttaacttgg tacatgagtt gtcattggtt gcccaatcta ttgaggcgac
    16441 tttgtctgaa aaagatctcg tggcagaaaa ggttcaagct ttgctaacta ctactcgtaa
    16501 tgctttttac atcgggcgtg gcaatgatta ttacgttgcg atggaagctg ctttgaaatt
    16561 aaaagagatt tcttatattc aatgcgaagg ctttgcggct ggtgaattga aacatggaac
    16621 catttcatta attgaggagg acacgccagt aatcgcttta atatcgtcta gtcagttggt
    16681 tgcctctcat acgcgtggta atattcaaga agttgctgcc cgtggggctc atgttttaac
    16741 agttgtggaa gaagggcttg accgtgaggg agatgacatt attgtcaata aggttcatcc
    16801 tttcctagcc ccgattgcta tggtcattcc aactcaactg attgcttact acgcttcatt
    16861 acaacgtgga cttgatgttg ataagccacg taatttggct aaagctgtaa cagtagaata
    16921 aatgattata atggataagg caaccatctg ttaggtggtt gctttttgtt tttaggagaa
    16981 tagcagagct tagaaaatgg ccttgagaaa agctatacaa gaagaatagt catcttctga
    17041 tgagaacgta ttcatcttgt caaatccttg attctaaagt aaaatggtaa cattaagaaa
    17101 tgtttaggag tgtaagatgt cattaccaaa ttgtttgcaa tgccagtctg aatatgttta
    17161 cgaagatggt cttttattaa tctgtccaat gtgtgctttt gaatggacac caggcgaaga
    17221 agcgactgaa gaagaaggac ttgttgtttt agatagcaat ggtgttcgat tatctgatgg
    17281 cgatactatt actgtggtta aagatttgaa agtaaaaggc gctccaaaag acctgaaaca
    17341 agggactcgt gttaaaaata ttcgcctggt ggaaggtgat cataatattg attgtaagat
    17401 tgatgggttt ggcgcgatga aattgaaatc agaatttgtc aagaaaatct aataataata
    17461 cgcaaccagc tgatctggtt gtatttttat aaaaaaacct ctccccaaat acgttcaaat
    17521 ttggtataat agtaaaatat tcagttttag gaggcaacat gacctatatt cagcaagttt
    17581 tacccagctt attagatggt gccttggtga ccttacaagt attctttatt gttatcattc
    17641 tttctatacc cttaggggct attttagctt tcttgatgaa gattcccttt aaaccgctac
    17701 agtggttttt gaccctatac gtgtggatga tgcgagggac accattacta cttcaattga
    17761 tttttttcta ttatgttttg ccaagtgtgg ggattagttt tgatcgaatg ccagctgcta
    17821 ttttggcgtt tactttgaat tatgctgcct actttgctga aatttttaga ggtgggattg
    17881 aggctattcc aaaaggtcaa tatgaagcag ctaaagtatt aaagttaaaa cctcttcaaa
    17941 ccattcggta tattattttg cctcaagtgt ttaaaattgt gttaccaagt gttttcaatg
    18001 aagtcattaa tttggtcaaa gattcttccc ttgtctatgt actcggtgta ggagatcttt
    18061 tattagcaag taagacggca gccaataggg atgcaacctt agcccctatg tttatcgctg
    18121 gtcttatcta tttgctttta attggactgg tcacgattat ttcaaaacaa gttgaaaaac
    18181 ggtttaatta ttatcagtaa ggaggcttca tgttagaact caaaaatatt tccaaacagt
    18241 ttggtcaaaa aaccattttt gatggcttta atctaaccgt tcaagacgga gaagtgctct
    18301 ctttggtagg cccatcaggt ggcggtaaga caacactctt acggatgttg gctggtcttg
    18361 aatctattga ttcaggtcaa gtcttttaca atggcgaaga tgttggtatt gatcatttgg
    18421 aaaatcgtaa cttgcttgga tttgttttcc aagattttca attgtttcct catcttaccg
    18481 ttttagacaa cctaacgctg tctccaacaa ttacaatggg caagcaaaag gctgacgcta
    18541 aagaaaaggc tttggattta ctggcacgtt taggattaaa agaacatgcc caagtttatc
    18601 cctattcgtt atctggaggt caaaaacaac gggttgcttt ggcaagagcc atgatgattg
    18661 accctcaaat tatcggttac gatgaaccga ccagtgctct agatcctgaa ttacgtcaga
    18721 cggtagaagc cttgattgtt caaaaccgtg aaatgggaat aactcaaatt gtagtcactc
    18781 acgatcttgt ttttgccgaa gccatctcag atcgtattat tagggttaat cctaaataga
    18841 agaggaccca aaagatgatt ataaaaaaaa gaaccgtagc aattttagcc atagctagta
    18901 gctttttctt ggtaggttgt caagctacta aaagtcttaa atcaggagat gcttggggag
    18961 tttaccaaaa gcaaaaaagt attacagttg gttttgacaa tacgtttgtt cctatgggct
    19021 ataaggatga aagcggcaaa tgcaaaggtt ttgatattga tttggctaaa gaagtttttc
    19081 accaatatgg actcaaggtt aactttcaag ctattaattg ggacatgaaa gaagcagaac
    19141 taaacaatgg taaaattgat gtaatctgga atggttattc aataactaag gagcgtcagg
    19201 ataaggttgc ctttactgat tcttacatga gaaatgaaca aattattgtt gtcaaaaaaa
    19261 gatctgatat caaaacaata tcagatatga aacataaagt gttaggagca caatcagctt
    19321 catcaggtta tgactccttg ttaagaactc ctaaactgct gaaagatttt attaaaaata
    19381 aagacgctaa tcaatatgaa acctttacac aagcttttat tgatttaaaa tcagatcgta
    19441 tcgatggaat attgattgac aaagtatatg ccaattacta tttagcaaaa gaagggcaat
    19501 tggagaatta tcggatgatc ccaacgacct ttgaaaatga agcattttcg gttggactta
    19561 gaaaagaaga caaaacgttg caagcaaaaa ttaatcgtgc tttcagggtg ctttatcaaa
    19621 atggcaaatt tcaagctatt tctgagaaat ggtttggaga tgatgttgcc actgccaata
    19681 ttaaatctta aaaaggacac ttgtcctttt tttgtttaac aggtgagatc tagcagacaa
    19741 agtcagctag acgatttaat aaaaatctta gtttaaggtt ttttattaaa ctgtattttt
    19801 tctaaaaatt atagtttttt taaaactgat aaatgacaag agaagttatt tt
//
LOCUS       DAUCXI010000033        19383 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.033, whole genome shotgun sequence.
ACCESSION   DAUCXI010000033 DAUCXI010000000
VERSION     DAUCXI010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19383
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.033"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            254..1048
                     /locus_tag="VGY43_001300"
     CDS             254..1048
                     /locus_tag="VGY43_001300"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEQ4302480.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDRGMAAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQSDGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            1073..1714
                     /locus_tag="VGY43_001301"
     CDS             1073..1714
                     /locus_tag="VGY43_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEQ4302481.1"
                     /translation="MKIALINENSQAAKNGIIYDALTSVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPMGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEPSELVTYLKSVLEQ"
     gene            1743..2744
                     /locus_tag="VGY43_001302"
     CDS             1743..2744
                     /locus_tag="VGY43_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEQ4302482.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLD
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMSLTAWQGHRVGLYYLENGFGCRASQV
                     YYDRCGSSFSALDKDSLDLAAIFEGIRHFHFSGISLALGKKTQDLIEVLVREAKKRDI
                     CVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADATMI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQRNLDFAVATASLKCTVAEDQLYHSVQQVEAVLANQRDVQR"
     gene            2749..3384
                     /locus_tag="VGY43_001303"
     CDS             2749..3384
                     /locus_tag="VGY43_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEQ4302483.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHRYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGMSFIRAIKSPLPQVEVMV
                     TGGVSLDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            3681..4331
                     /locus_tag="VGY43_001304"
     CDS             3681..4331
                     /locus_tag="VGY43_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEQ4302484.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITADYDAYKQAHKPPYQKLLITEVNSCLEQLKKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            5028..6152
                     /gene="queG"
                     /locus_tag="VGY43_001305"
     CDS             5028..6152
                     /gene="queG"
                     /locus_tag="VGY43_001305"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEQ4302485.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVIEDRISPERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGFDYH
                     YVVGEKLDRLSKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDKPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNPPATEIDPELAQPELIPFLSLSN
                     GQFKEKFGMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEILAFMSHLTLKDEDSQKELELIRHKWQF"
     gene            6221..7319
                     /gene="prfB"
                     /locus_tag="VGY43_001306"
     CDS             join(6221..6292,6294..7319)
                     /gene="prfB"
                     /locus_tag="VGY43_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEQ4302486.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMNGEINGFIDAYLKWRIED"
     gene            7338..8030
                     /gene="ftsE"
                     /locus_tag="VGY43_001307"
     CDS             7338..8030
                     /gene="ftsE"
                     /locus_tag="VGY43_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEQ4302487.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            8023..8952
                     /locus_tag="VGY43_001308"
     CDS             8023..8952
                     /locus_tag="VGY43_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302488.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(9261..9959)
                     /locus_tag="VGY43_001309"
     CDS             complement(9261..9959)
                     /locus_tag="VGY43_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ4302489.1"
                     /translation="MPFIFRHSFFNKALIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPTPGHSWGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            10127..10891
                     /locus_tag="VGY43_001310"
     CDS             10127..10891
                     /locus_tag="VGY43_001310"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HEQ4302490.1"
                     /translation="MSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQAAVD
                     KLSPEDTVAVVADVSKRDQVFDAFQKVVDTFGDLNVVVNNAGVAPTTPLDTITEEQFE
                     KAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGCEGNPNLTVYGGTKFAVRGI
                     TQTLAKDLASEGITVNAYAPGIVKTPMMFDIAHEVGKNAGKDDEWGMEQFAKDITLKR
                     LSEPEDVANAVGFLAGDDSNYITGQTIVVDGGMVFH"
     gene            10999..13500
                     /locus_tag="VGY43_001311"
     CDS             10999..13500
                     /locus_tag="VGY43_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEQ4302491.1"
                     /translation="MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLGHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGPKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFH
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYNYDFWRVNYEKAKTARLLITNHAYFLHRVQDDKDFAR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRL
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETDCFLI"
     gene            13835..15028
                     /locus_tag="VGY43_001312"
     CDS             13835..15028
                     /locus_tag="VGY43_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEQ4302492.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKAAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            15049..16395
                     /gene="asnS"
                     /locus_tag="VGY43_001313"
     CDS             15049..16395
                     /gene="asnS"
                     /locus_tag="VGY43_001313"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEQ4302493.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITD
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            16810..17700
                     /gene="rapZ"
                     /locus_tag="VGY43_001314"
     CDS             16810..17700
                     /gene="rapZ"
                     /locus_tag="VGY43_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEQ4302494.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     EGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYKVELREKTGLDEDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            17697..18674
                     /locus_tag="VGY43_001315"
     CDS             17697..18674
                     /locus_tag="VGY43_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEQ4302495.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNENDGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYQGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            18671..>19383
                     /gene="whiA"
                     /locus_tag="VGY43_001316"
     CDS             18671..>19383
                     /gene="whiA"
                     /locus_tag="VGY43_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEQ4302496.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSLIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKT"
BASE COUNT         6002 a         3299 c         4149 g         5933 t
ORIGIN      
        1 atttttgaaa aagaaaaagt gagcagttgt gctaaaaaag aatcaaaaat ggtctttttt
       61 gtcactattt aatgtagaaa agtcttaata gctattaagt ataggacaag actaaacaag
      121 aatgacagtt tggataagag cactctttta aatttttgaa ccgttttcat taaaatgatt
      181 gacaaaacta gtttactttg ttatagtctt ggtaaacagg tttacttaat ttaataacaa
      241 aaaggagaat cctatggaaa atatgttttc gttacaaggt aagattgcct tgattaccgg
      301 agcatcctac ggtattggtt ttgaaattgc caaagcctat gctcaagcgg gtgcaactat
      361 tgtgtttaat gacatcaaac aagagttagt tgatagaggg atggctgcct atcgagaatt
      421 agggatagaa gcgcatggct atgtttgtga cgtgactgat gaagctggta tccaacagat
      481 ggttagtcaa attgaagatg aagtaggtgt tattgatatt ttggtcaaca atgcaggtat
      541 tattaggcgt acgccgatgc ttgaaatggc cgcagaagat tttcgtcaag ttattgatat
      601 tgatttaaat gctcctttta ttgtgtcaaa agctgtatta ccatcaatga ttgcaaaggg
      661 acatggtaaa attataaata tctgttctat gatgagcgaa ttggggcgtg aaacagttag
      721 tgcctacgcg gcggctaaag gtggcttgaa aatgttaacc aaaaatatag cctctgagtt
      781 tggagaagcc aacattcaat gtaatgggat tggtcctggc tacattgcaa caccacaaac
      841 agctccgttg agagagcgac aatcagatgg tagtcgtcat ccttttgatc aatttatcat
      901 tgctaaaaca ccagcagcac gttgggggac aacagaagac ttagctggtc cagctgtttt
      961 tctagctagc gatgccagta attttgtcaa cggccatatt ctttatgtcg acggtggcat
     1021 tttagcttat attggaaaac aaccttaatc acacactaga aagagatttt atatgaaaat
     1081 tgcattaatt aatgaaaata gccaagcggc taaaaatggt attatttacg atgcccttac
     1141 ctcagtgaca gataaacacg gctaccaagt ctttaactat ggcatgtatg gcacagaagg
     1201 tgaaagccag ttgacctatg ttcaaaatgg actcttagct tctattttat tgaccactaa
     1261 ggcggctgat tttgtggtga ctggttgtgg gacaggtgtt ggagctatgt tggccttgaa
     1321 cagcttccca ggtgttacct gtggttttgc gagtgagcca acagaagcat atctcttttc
     1381 tcaaatcaat ggtggtaatg ccttgtccat tccttttgcc aaaggttttg gttggggagc
     1441 agagttgaat ttgaccttaa tatttgaacg cctctttgca gaaccaatgg gtggtggtta
     1501 ccctaaagag cgagctattc ctgaacagcg gaatgcacgt attttaagtg atttgaaaaa
     1561 aattacttac agagatttgt tggcaattgt caaagacatc gaccaagatt tcctcaaaga
     1621 aacgatttct ggcgctcatt ttaaagagta cttctttgcc aatgcggagc cgtcagaatt
     1681 agttacttat ttgaaatcag tacttgaaca gtaattccat tttgacgagg aaaggaggtc
     1741 acatgtctaa gttattattg gttggtgaac cgctgattcg cgttagcccc aatcagtttc
     1801 agcctttgac caatgcctgc gacgctcagc tttttttcgg cggttcagaa gttaatattg
     1861 caagaactct agacggtttt ggcttagaag caaggctatt tacggcccta ccagataatc
     1921 ctgttggtca cgcttttcat cagtttttga agcaaagcgg cgtggatatg tccttgacgg
     1981 cttggcaagg tcatcgcgtt gggctatatt accttgaaaa tggctttggc tgtcgggcta
     2041 gtcaggttta ttatgaccgc tgtggctcta gcttttcggc cttagataag gatagtcttg
     2101 atttagctgc catttttgaa ggcattcgtc actttcattt tagtgggatc agtttggcgc
     2161 tgggcaaaaa aactcaggac ctgattgagg tacttgtgag agaagctaag aaaagggata
     2221 tttgtgtttc ttttgatctt aactttagat ctagtatgat tgcggtagct gatgctaaac
     2281 gactcttttc tcactttgct caatacgcgg atattatttt tggcatggaa cctttgctgt
     2341 tagatagtga cgattttgac atgtttgata ggaataaggc agatgctacg atgattagag
     2401 aacgtctggc aggactttat cagcgctatc agttacaagc tatttaccat acggagcgtt
     2461 caaatgatgc ccaaggcagt aatcgtttca aggcttatgc ctatgatggg cagttttacg
     2521 aatcctgtga agtgacgacc ccagtcttgc aacgggttgg aagtggagat gcttttgtgg
     2581 cgggtttact ttatcagttg ttagaaggta acgaaaagca gcgcaacctt gattttgctg
     2641 tggcaacagc tagcctaaaa tgtacagtag ctgaagatca gctctatcac agcgtccaac
     2701 aagtagaagc agtcttagct aatcaacgag atgtccagag gtgatgatat gggaaaaata
     2761 gaaatcttaa ccaaacttaa ggctaatcgg cttgtcctgg ttgtacgagg agagtctagt
     2821 gaggaagctt tagcttgcag cctggccagt attgaaggtg gcattaagac aattgaagtc
     2881 acctatacta acccctttgc tagtgaggtt atcggtcaat tagctgaacg cttcaaagaa
     2941 gatcctgagg tattgatagg tgctgggaca gttttggatg atgtcactgc ccgccaagct
     3001 attttagcag gagcacagtt tattgttggt cctaatttca atcgagcagt ggctttgatt
     3061 tgtcatcgtt atagcatacc ttatttacca ggttgtatga cggttaatga agtggttaca
     3121 gcattagaat caggggttga tatggtcaaa atttttcctg gttctactgt agggatgtcc
     3181 tttattcggg caatcaaatc tcctttgcca caagtagagg ttatggttac aggcggagtt
     3241 tctttagata atctcaaaga ctggctagct gctggagtag atgttttagg cataggaggc
     3301 gagtttaatc agttagcgag ccaaaaacaa tataacctaa tcactaagaa agccgctcat
     3361 tatatcaaaa gtttgcgaca ataatctaaa aaacgttttt accttggctt tagtgctagt
     3421 aaaaacgctt ttttatcatt cattcaatta atatgcttct gcttatgttt ttccagatag
     3481 tatagatata agagcagcta atttaacaag atgagcctgt cgtttgatat ataggatata
     3541 aactttttat gatcaaacaa aagtaatacc ttttgaattc gttagtattg acctgatcta
     3601 aagtgatatc acttagaatg aactagctgt acagctttta cagcaactta tgctaaaata
     3661 gaaaaaaagg agaaatgttg atgattaaag gaattatttt tgatatggac ggtgttttat
     3721 ttgatacaga acctttttat ctgaggcgac gagaagattt ttttaagaca aagggaattc
     3781 ccattgatca tttgaactct aaagatttta ttgggggcaa tctccaagaa ttatggaaag
     3841 agttgttagg taaaaatagg gatgatgcta tcgttaaggc aattacagct gactatgacg
     3901 cttacaaaca agcgcataag cctccttatc aaaaactgtt gattacagaa gtgaactctt
     3961 gtcttgaaca gttgaaaaaa caaggtatta aactggctgt ggcatcaaac tcgaagcgtc
     4021 aggatgtttt gttggcgttg gagacaacgc aaataaaaga ttattttgaa ataatcctag
     4081 cgcgtgaaga tgtttctaga ggcaaacctt atccagatat ctataataaa gcagtacaaa
     4141 aactaggatt acaaaaaaaa caactgcttg tagtagaaga cagccaaaaa ggcattgctg
     4201 ccgccaaagc agccaatctg acagtttttg ccattaccga ctaccgatat ggcattgatc
     4261 agagtcaagc tgatcacaag atagatcatt taggacaact gtgtgtaaaa atcggttgtt
     4321 ttggatcgtg aagtaacgca actaactgat cattgatgat acttcaagac acttaagaat
     4381 acgtctagga ctttctacag accaataaca agaatacgtt tatgtgtttt tactgttttt
     4441 ttagctacct atttacaata tgacactgaa aagagtacta tgtttaagtt attatcaaaa
     4501 aaaccgtcgc ataagatcac ctagaaaagg attatgattt ttgtgatttg gatgcgatcg
     4561 ttagtcgttg accatcttta tgtggcagga gatatgttta accgtggtca ttatttggat
     4621 ttgtttttag attggctagt gagtaaatat agaaggatca taatactgct ttgacaaagg
     4681 cagtatctga gtccatgagt tgcacggata atgtgactcg gttttggtta gctataataa
     4741 tatttggaag tgttatgctg cttgtcttcg taggtccatt gattatagtc agacttactt
     4801 tagagctgag ctgactgtct agacaagacg tgatggagat gtgatttctg accaagtaga
     4861 ggtaaccaga aaagggactt ttacgatgta attgaattta cttgttgcat tcttgtgcat
     4921 gttaagagag aaaacccaga taaatcagga agtaaaatgg ttatgtttga ttagaattgt
     4981 ccttcttttt ccttgaagtc ttaacttatt ttgattatga tagtagtatg actattaagg
     5041 cagaaattaa ggcactcgcc aaagaaattg gtatctctaa aattggtttt acgacggcag
     5101 ataactttga ttatttggaa aagtcattgc gtgcttctgt ggaagagggg cgcaattcag
     5161 gatttgaaca taaagtcata gaggatcgta tctcccctga aaggctttta gaatcggcta
     5221 aaacgattat ttcaattggc gttgcttatc ctcacaaact tcctcagcaa cctcaaaaaa
     5281 caccttataa acgtggcaaa attacaccta gttcgtgggg gtttgattat cattatgtgg
     5341 tcggcgaaaa gttagacaga ctatcaaaag gcattgaaga gctgtgtcga gattttcctt
     5401 tgcaacaaaa agcaatggtc gatactggag ctttagttga tactgcagtt gcccaaagag
     5461 cgggtattgg ttttatagga aaaaatggtc tagttatttc taaagaatat ggctcttata
     5521 tgtttttggg agaattaatt accaatttag agatcgagcc agacaagcct gtcgattatg
     5581 attgtggtga ctgtcgtcgt tgtctagatg cctgtccaac ttcttgttta attggtgatg
     5641 gctcaatgaa tgccaagcgt tgtctatcat ttcaaaccca agataaggga atgatggaca
     5701 tagagtttcg aaaaaagatt aaaacagtta tctatggttg tgatatttgc caaatttgct
     5761 gtccttataa caaaggtata aataatccac cagctacaga gattgatcct gagttggctc
     5821 aaccagaatt aataccattt ttgagtttat caaatggaca atttaaagaa aaatttggta
     5881 tgattgctgg aagttggcga ggtaaaaata ttttacagcg taatgccatt attgcgctag
     5941 caaatgctca tgataaaacc gcagtggtca aattaataga gattattgat aaaaataata
     6001 accctattca tactgcaaca gctatatggg cattgggaga aattgtcaaa aaaccaaacg
     6061 atgagatact ggcgtttatg agtcatttaa ccttaaaaga tgaagatagc caaaaagagt
     6121 tggaattaat ccgtcataaa tggcaatttt aagcctttta tggtattttt aagaacctta
     6181 tgataaaata aaacagatta acaaagattg gagaaatctc atggaagtgg ctgaaattcg
     6241 ccaaaaaata gtagaaaata aagagaagtt gactagcttc aggaggtctc tttgacttag
     6301 atcgtttgga agaggagatt gctcttcttg aaaatcacat gactgagcca gacttttgga
     6361 atgacaatat tgcagcgcaa aagacatctc aagaactaaa tgaattaaaa ggtaagtatg
     6421 atactttcca taatatgcaa gaattatctg acgaaacaga actcttactt gagatgcttg
     6481 acgaagatga ttctttgaaa gaagaattag aagaaaatct aatgcagcta gataagataa
     6541 tgggtgctta tgaaatgacg cttctcttat ctgaacccta tgaccacaat aatgctatct
     6601 tagaaatcca tcctggttca ggaggaactg aagcgcaaga ttggggagat ttactcttac
     6661 gaatgtatac ccgttttggc aatgctaatg gtttcaaagt agaagtattg gattatcaag
     6721 caggggatga agctggtatt aaatcggtta ccctctcttt tgaaggtccc aatgcttatg
     6781 gtttgttgaa atcagaaatg ggagttcatc gcctcgttcg tatatcacct tttgattcgg
     6841 ctaaacgtcg tcatacctca tttgcttcag ttgaagtgat gccagagtta gatgatacga
     6901 ttgaagtaga agtacgtgat gatgacatta aaatggatac tttccgttcc ggaggagctg
     6961 gtggtcagaa tgtcaataaa gtatcaacag gtgttcgttt gacgcatatt ccaactggaa
     7021 ttgtggtatc gtctaccgtt gaccgtactc aatatggaaa ccgcgatcgc gctatgaaga
     7081 tgttgcaggc taagctatat cagttagaac aagaaaagaa agcacaagaa gtagatgctc
     7141 tcaagggtga taaaaaagaa atcacttggg gaagtcagat tcgttcttat gttttcactc
     7201 cttatacgat ggtgaaggat catcgtacta actttgagct tgctcaggta gataaggtta
     7261 tgaatggaga aatcaatggc tttattgatg cctaccttaa gtggcgcatt gaagactaaa
     7321 aataataaag gagaaacatg gcactaatag aaatgtctgg tgttactaaa aaataccgcc
     7381 gctcaacgac cgccctcaga gacgtcaatg tttctgttaa ccaaggtgag tttgtttatc
     7441 tcgtaggccc atcaggtgct ggtaaatcaa cttttatcaa actcctttac cgtgaagaac
     7501 aactgacaac tggtaagcta tatgtgggtg aattcaattt aactaaacta aaagcacgtg
     7561 atgttccgat tcttcgtcgt cacatcggag tagtttttca agattacaaa ctgctaccaa
     7621 gaaaaacagt ctttgaaaat gtagcttacg ccatggaagt tattggtgaa aagcgccgcc
     7681 acattaaaaa acgcgtgcca gaggtactcg atttagttgg cttgaaacat aagatgcgtt
     7741 cttttccaag tcagctatca ggaggggagc agcaacgtgt ggccattgcg cgtgcgattg
     7801 ttaacaaccc taaattattg attgcagatg aaccgacagg gaatttagat cctgagattt
     7861 catgggaaat tatgcagtta cttgaacgta ttaatgttca gggaacaact atcttaatgg
     7921 cgacacacaa cagtcatatt gtgaatacat tccgtcatcg tgttgttgct attgaagatg
     7981 gtcgcatagt acgtgatgaa gaaaaaggag attatggtta cgatgattag atactttttc
     8041 cgtcatattt gggaatccat taaaaatctt aaacgcaact tttggatgac atttgcttca
     8101 gttagtatgg tggctgttac attgacttta gttggtgttt ttgcggcgac attgttgaat
     8161 atacagcgtg ttgcttcggg tgttgaaaat aatgtccata tcaataccta cttacaagtt
     8221 gattcaactg atgctgcaaa agttattcaa aatactgccg gtgaacctgt taataacgat
     8281 aactaccaca gtgtttacga caaaattgct cagataaaag gtgtcaaaaa gattacattt
     8341 tctagcaagg atgaacaatt gaaaaaattg caagaaacct taggtgatgt ttggaatatg
     8401 tatgaccaag acactaatcc gctccaagat atctatctta ttgagaccca gacgcctaaa
     8461 caagttaagg cgatcactaa aaagatcaga acgattgaag gcgtagaagc cgcagattat
     8521 ggagggatta actccgataa actatttaag ttttcaacat taattcaaac ttgggggctg
     8581 atcggaacag caatgctatt atttgtagct gtctttctca tttcaaacac tattcgtatg
     8641 actattatgt ctcgtaaacg cgacattgaa attatgcggt tagttggtgc taaaaattct
     8701 tatattcgag ggcctttctt ttttgaaggg gcttgggttg gcttgttagg agctgtttta
     8761 ccatctcttc tgatttatta tggatatgat cttgtttata agcattttgc acaagaatta
     8821 caacgtaata atctctcgat gtatccgctt gatccttatg tatattacct gattggtgct
     8881 ttgtttgtca taggtattat gattggttcg cttggttcag tgctttctat gagacgttat
     8941 ttaaaattct aaaaaagcgc tgctgacgaa acgtagcgac cctcaaaagt tggacctctt
     9001 atgttattcc aaggacttcg ttttgtattg cacaggactg gtccttttca ttttgttttg
     9061 attcatttgt ttatttgtaa taggcaatat agtttaaaat agcagtttct aaggtttcaa
     9121 gagaagaaaa gcaccccaaa agttagatgt ttgatgtatc taacttttgg ggtgtcattc
     9181 aaaatttagt ggctcttttt tagtaaaata ctatgatttc agttttagga taacctcaaa
     9241 cagtatctaa aatagctatg tcaatgaaaa aaggggttag catttttttc gtgacaaatg
     9301 gtagtagaag gaccatgccc aggataaact cggtaatgat taggtaaggt gaatagttct
     9361 tggcgaatac cagtaatgag gtcctcaaag ttactggtag gtaagtcagt acgaccgata
     9421 gtttcacgaa atagagcatc gccagtaacg actaattcat ctgagtggaa aacaaatgag
     9481 actcctcccc aagaatgacc aggtgttggt aaaactgtga attcaaaacc atttagttga
     9541 tagggttgct ttaatttaaa aaagttctct gccggtcttg ctataacagt aatgatatca
     9601 tcatgacggc ctaagccaga taaattatca tctggggaag atagccaagc ggcttctttt
     9661 tctgaaacat aaacaggtgg atgatcaaaa gcatctctga ccaaatctaa actaaaaata
     9721 tgatcataat gagtatgcgt taagaggata gccactaaag gtttttcaaa ggatttaatt
     9781 ttagcaatga tttcttggcc gttacttcct ggatcaatga ggataacagc ttgatcatta
     9841 acgaggtaat aagtattttc accagcaatg tggtttattg ttttatagat tttcataagg
     9901 atagtgtacc aaaaaatcaa ggctttgtta aaaaaagagt ggcggaaaat aaatggcaat
     9961 tagtttcaga aaatatgaga tctcacagca atttcttgac accgttttca taaaggtgta
    10021 tcataaaagt aatcaataag ccaagcctaa agctgaactt agtttaagaa cactgacttt
    10081 ttgagagcaa cctaatcggt tgactaaaaa atatgaggtg gaagatatgt caaaagttgc
    10141 tattgttact ggtgctggtc aaggaattgg atttgctatt gcgaaacgtc ttcatgcaga
    10201 cggctttaaa ataggcattt tagactataa tgaagagact gctcaggctg cggttgataa
    10261 actatcacct gaggatactg ttgcagttgt agcagatgtt tcaaaacgtg accaagtttt
    10321 tgatgctttc caaaaagttg tagatacttt tggtgatttg aatgttgttg ttaacaatgc
    10381 aggtgttgcc ccaacaaccc ctcttgacac gattactgaa gagcagtttg aaaaggcttt
    10441 tgcaatcaat gtcggaggaa cgatttgggg aagccaagca gctcaaaaac attttagaga
    10501 attaggtcat ggcggaaaaa ttataaatgc aacatcacaa gcaggatgtg aagggaatcc
    10561 taatttgact gtttatggtg gtacaaaatt tgcagttcgt ggtattacac agactttggc
    10621 aaaggatttg gcatcagaag gaatcacagt caatgcttac gcaccaggta ttgttaaaac
    10681 acctatgatg tttgatattg cccatgaagt tggtaaaaat gcaggcaaag atgatgaatg
    10741 gggtatggag caatttgcaa aagatatcac tttgaaacgc ttgtctgaac cagaagatgt
    10801 tgctaatgca gtaggcttct tagcgggaga tgattcaaat tatatcactg gacaaacaat
    10861 agttgtcgat ggtggtatgg tattccatta aaaatgatta atactgacac tgtgagtttc
    10921 actcacagtg ttttttaaga agtataaaaa attatcctat cttggttatt ggagtgatgg
    10981 cacctttgag atatagtcat gttttgtttt atagatatag cgtgctataa tagacttact
    11041 atgacccaga aaaaacttag aaaatatgca gtagtggact tggaagctac tggagcaggt
    11101 cccaatgctt ctattattca ggttgggatt gttattatcc aaggaaataa aattattgat
    11161 agttatgaaa cagatgttaa tcctcatgaa tctttagatg agcatattgt tcatttgaca
    11221 ggtattacgg ataagcagtt ggctaaagct ccggattttg gtcaagtggc gcatcacatt
    11281 tatcaattga ttgaagattg tatttttgtt gcccacaatg taaagttcga tgcaaattta
    11341 ttggcagaag ctcttttttt ggaaggatat gagttaacaa taccacgtgt tgatactgtt
    11401 gaattagccc aactattttt ccctcgcttt gaaaagtata accttggtca cctatctagg
    11461 cagctcaata ttgatttggc agaagctcat actgctattg cagatgcaag agctacagct
    11521 atactgtttt taagactttt acaaaaaatt gagagccttc caattgagtg cttagaaagc
    11581 ttattagtct attcagatag cctgctattt gaaacagcaa tggtcattca agaaggatta
    11641 gccaaagcca aaccttatga tcccaacaaa tacattaaaa tcagacagat tctcttacca
    11701 aagggcccaa aagctctcaa gccttatcaa atatcaaaaa gcttccctat taatatggca
    11761 ctattaggtc tggaagaaag gcctaaacag actcaatttg ctcagttaat tgacgaagat
    11821 taccatcagg gagtagctag ttttattgaa gctcagacag gtattggaaa aacctacggc
    11881 tacctgctac ctcttttggc aaaagaagat caaaaccaaa tcattgtcag tgtgccaacc
    11941 aaacttcttc aagaccaatt aatggctggt gaagtagctg ctattcaaga acaatttcac
    12001 atcgcctgcc atagtttaaa aggacccgcc aattacctaa agctagatag ctttgcagat
    12061 agtttggacc aaaatgacca gaaccgtttg gtgaatcgtt ataaaatgca attattggtt
    12121 tggctcttag aaactaagac aggagacctt gacgaaatca aacaaaagca gcgctttgcc
    12181 gcttattttg agcagcttaa gcacgatgga gacattaagc agtcttctga attttacaat
    12241 tatgattttt ggagagttaa ttatgaaaaa gccaaaacag cccgtctcct gattaccaac
    12301 catgcttatt ttttacaccg tgttcaagat gacaaggact ttgctagaaa caaggtcttg
    12361 gtctttgatg aggcccaaaa gctgatgctc caattagatc aattatcacg tcatcagctt
    12421 aacctgacgg tttttttaca aacaatacag gccaagttaa gcaacccttt acctctttta
    12481 gaaaaacgct tattggaaag cttgtcgttt gaactgggac aagtgtcaag tgattactat
    12541 caaaataaag agcaccagct tgctcatgat tggtctcgta tagctggcta cgccaaagaa
    12601 ttaacaggag cagattatca agagttacaa gccttttttg ctacctcaga tggtgactac
    12661 tggcttagta gcgaaaagca agaggagaag cggttgactt atctaaacag tgctagtaag
    12721 gcatttattc atttccaaca gctcttaccc gaaacggtga aaacttattt tgtttctgcc
    12781 actttaacca tcagctcaga agtaaccttg gcagacctat taggttttga agagtatctc
    12841 tatcatgtca ttgaaaagga taaaaagcaa gaccagttgg tgcttgttga tcaagaggcg
    12901 cctatcgtga cagaagtcag tgaccaaatc tatgtggaag caattgcaaa acgaatcgaa
    12961 agcttgaagc aagagggtta tcctatttta gtgcttttta attctaaaaa acacttgctg
    13021 ttggtttcag actatctaga ccaatggcag gtgcctcact tagcgcagga aaagaatgga
    13081 acagcttata atattaaaaa acggtttgat caaggagagc aaactatttt gcttggttta
    13141 ggttcttttt gggaaggagt tgattttatt caagcggatc gtatgattac ccttatcgca
    13201 cgattgccct ttgataaccc agaggatttc tttgttaaga aaatgagtca ttatctattg
    13261 gaaaaaggta aaaatccttt cagagattac ttcttgccaa tgactatttt gcgattaaaa
    13321 caggctattg gtcgcacgat gcgtcgacaa gatcaaaagt cagtggttat tattttggat
    13381 cgtcgtctcc ttacaaagtc ctatggacaa gttattttgg aaggtctcgg tcaggaattt
    13441 ttgatttctc aacaaaattt tcacgattgt ctagtagaaa cggactgttt tttgatataa
    13501 tagaaaggat ctattatatc agaaaaattt ttaatggcgt taagcacaat caactaacat
    13561 ttaaattagt ttgaactttt attatgctct tttagacaac tgttcacatg ttttcgaatt
    13621 gtttttttga taaggacaat aaatgaacaa atttttggtt ttagtaaacc caattactgt
    13681 tcttttcatt agtgtcagtt gctatcaaaa cagcttgtca tagttcgtgc gatcagtagc
    13741 gagtattggt aaaactgaaa ccgtagatta tgaaaaaatg atctgttgat cattaattaa
    13801 tctgaagata agaagtcgat aaaaaggaga tacgatgccc aaactatcaa agcgagtttt
    13861 agaaatgaaa gagagtgtta ctctggctgc aggtgctaga gctaaggctt tgaaagcgca
    13921 gggccgcgat gtactgaatt taactttagg agaaccagat ttttttacac ctaagcacat
    13981 tcaagacaag gcgattgaat ctattcaaaa tggtacggct agcttttata caaatgcttc
    14041 tgggcttcca gaattaaaag ctgcgattgc cacatacctg aaaaatcagt atgggtatca
    14101 cttgtctcct gatcagattg tggcaggaac aggtgccaag ttcatccttt atgccttttt
    14161 tatggctgtt ttaaatcctg gtgaccaagt tctcattcca acaccatatt gggtatctta
    14221 ttctgaccaa gtaaaaatgg cagaaggtca gccgatcttc gttcaaggac tagaagaaaa
    14281 tcaattcaag gtaactgttg accagctgga aagagcaagg acaagtaaga ctaaagttgt
    14341 ccttatcaat tccccttcca atccaacagg tatgatttat ggtgctgagg aattaagggc
    14401 cattggagaa tgggcggtgc acaacgatat tcttattctg gcagatgata tttacgggtc
    14461 cttagtctat aacggcaatc agtttgttcc tatttcaaca ctctcagagg cgattcgtcg
    14521 tcaaaccatt acggtcaatg gcgtggctaa aagttatgcc atgacaggct ggcgggttgg
    14581 ttttgcagca ggtgaaccag agatcatttc ggcaatgagt aagatcatcg ggcagactac
    14641 ctctaacctg acaaccgttt cacaatatgc tgctatcgag gctttctgtg gtagtcagtc
    14701 atcacttgaa gagatgcgat tagcatttga agaacgcctt aatatcactt atccattgtt
    14761 gtgtcaggtc cctgggtttg aggttgttaa accacaagga gctttttact tctttccaaa
    14821 cgttaagaaa gccatggaaa tgacaggttt ttccgatgtg acaagctttg ctaatgctat
    14881 tttagaggaa gtcggattag ctgttgtgag tggagcaggc tttggcgcac cggaaaatgt
    14941 tcgtctgagt tatgctacag atatcgaaac ccttaaagaa gctgttcgta gactgcacgt
    15001 ctttatggaa agtaatgaaa ttaattaaat aaaaatagag agaaacttat gtcaaaaaaa
    15061 cttatttcaa ttgttgatgt taaagattat gttggtcaag aagttactat tggtgcttgg
    15121 gttgctaaca aatcaggtaa aggtaagatt gcgtttgtac agttacgcga tggttctgct
    15181 tttttccaag gtgtcgcttt taaaccaaac ttcattgaaa aatatggtga agaatcaggt
    15241 cttgaaaaat ttgacgttat taaacgtctc aaccaagaaa catctgttta tgtaacaggg
    15301 attgttaaag aggatgagcg ttctaaattt ggctatgagc ttgatattac tgaccttgaa
    15361 atcattggag agtcacatga atatcctata actcctaaag agcatgggac agacttcttg
    15421 atggacaacc gtcatctttg gttgcgttct cgtaaacaaa tggctgttat gcaaattcgt
    15481 aacgctatta tttatgcaac ttatgaattc tttgaccaaa atggttttat caaatttgat
    15541 agcccaattt tatcagaaaa tgcagcagaa gattcaacag agttattcga aacagactat
    15601 tttgggaaac cagcatttct tagccaatct ggtcaattat accttgaagc tggagcaatg
    15661 gctctaggcc gagttttcga ctttggtcca gtctttcgtg ctgaaaaatc taaaacacgt
    15721 cgccatttaa cagaattttg gatgatggat gctgagtatt ctttcttatc acatgaggaa
    15781 tcacttgacc ttcaagaagc ttatgttaaa gcattgatcc aaggcgttct agatcgtgcg
    15841 cctcaagcac ttgatatttt agaacgtgat gttgaggctc tcaaacgtta tatcacagag
    15901 ccattcaagc gtgtttctta tgatgatgct attacacttc ttcaagagca tgaagcagat
    15961 gaagatacag attatgaaca tttagagcat ggtgatgact ttggttcccc acatgaaact
    16021 tggatttcta attactttgg agtaccgaca tttgtagtga actacccagc aagctttaaa
    16081 gcattttata tgaaaccagt tcctggaaat ccagaacgcg ttctttgtgc tgatctttta
    16141 gctccagaag gttatggaga gatcattggc ggctcaatgc gtgaagacaa ctacgatgct
    16201 cttgtggcta aaatggatga actaggtatg gataaatcag aatatgactt ttaccttgac
    16261 cttcgtaaat atggctctgt tcctcatggc ggttttggta taggtattga acgtatggta
    16321 acttttgttg ctggtaccaa acatattcgc gaagctattc cattcccacg tatgttacat
    16381 cggattagac cctaataata caaaaaagtt catgtcatct atgaactttt tgtattggta
    16441 agaagtgagt gtgttataaa aacatcaata tgtcctaaag gagagataag aaatagtaga
    16501 gtttgaacct acatcctttg tgaagataaa ttttggaagt ttagtagatc agttagcaga
    16561 taagacaata tagccttgct caagggatat tttatagaca agtatttgga ctacgattat
    16621 caaatagaca ctctcatttg atactaaaaa ggtctcgtct attcctataa taggagagct
    16681 acgggagtta ttattaaaat tagctgattt ttacagttca aaatgtgtta ccactttttc
    16741 acttcttagc tttcttatgt atgtggtata atgaaggtgg acggttcgat agagaaaggg
    16801 aaattgtaaa tgtcagacaa acacattaat ttagttattg tgacaggaat gagcggcgct
    16861 ggaaaaacag ttgccattca gtcttttgag gatctaggct actttaccat tgataatatg
    16921 cccccagcct tggttccaaa atttttagaa ttaattgaac aaaccaatga aaatcgtagg
    16981 gtggctttgg ttgtcgatat gagaagtcgt ttgtttttca aggaaattaa ttctacctta
    17041 gatagtattg aaagcaatcc tagcattgat tttcggattc tttttttgga tgcaacggat
    17101 ggagaattgg tgtcacgcta taaagaaacc agacggagcc accctttggc tgcggacggt
    17161 cgtgtgcttg atggtattcg attggaaaga gaactcctat ctcctttgaa aagcatgagc
    17221 caacatgtgg tggatacaac aaaattgacc cctagacaat tgcgtaaaac catttcagac
    17281 cagttttctg aagggtctaa tcaagcctct ttccgtattg aagtgatgag ctttgggttc
    17341 aaatatggtc ttcctttgga tgcggatttg gtttttgatg tgcgttttct acccaatcct
    17401 tattataagg tagagcttcg tgaaaaaaca ggactagatg aggacgtttt taattatgtg
    17461 atgtctcacc cagaatcaga ggtgttttac aagcatttgt taaaccttat tgtccctatc
    17521 ttaccggctt accaaaaaga agggaagtct gtcttgacgg tggctatcgg ctgcacagga
    17581 ggccaacacc gcagcgttgc ctttgcccat tgcttggcag aaagtctggc aacagattgg
    17641 tcggttaatg aaagccatcg tgatcaaaat cgtcgtaagg aaacggtgaa tcgttcatga
    17701 aaaatcctaa aatgactgtt ataggtgggg gtactggcat ctccattatc ctaaaaagcc
    17761 ttcgtaatga agcagttgat attactgctg tggtcactgt tgcagatgat ggtggttcct
    17821 caggagaact tcgtaatgcc atgcaattag ccccgccagg agacttacgg aatgtcttgt
    17881 tagcgatgag tgacatgcca aaattttatg agcgggtttt ccaataccgt tttaacgaga
    17941 atgatggagc cttggctggt caccctctag gcaatctcat tattgctggt atctctgaaa
    18001 tgcaaggctc aacctacaat gccattcaaa ttttaaccaa atttttccat attacaggta
    18061 aaatttaccc ctctagcgag caggccttga cccttcatgc tgtttttaaa gatgggcatg
    18121 aagtagcagg agaaagttct attgccaaat accaaggcat gattgaccat gtctatgtga
    18181 ccaacaccta caacgaccaa aagcctcagg ccagtcgtaa ggtggttgag gctattctag
    18241 aaagtgacat gattgtcttg ggaccaggct cactgtttac ctctatttta cctaatttgg
    18301 tcattccaga aattaaagaa gctttgcgcc agactaaagc agaagtggtg tatatttgta
    18361 atatcatgac ccagtatggt gaaacagaac aattttcaga tgcagaccat gtggctgttt
    18421 taaatcagca cttaggaaga gatttgattg atacggtttt ggtaaatgtg gctaaggtgc
    18481 cgcaggctta catgaattct aacaaatttg atgaatacct cgttcaggtt gatcacgact
    18541 ttgctggcct ttgcagggct gctaagcgtg tgatttcgtc ttatttttta cggttggaga
    18601 atggcggagc ttttcacgat ggtaacttag tggtggaaga attaatgaat ttagtgagga
    18661 tagtcaagca atgagtttta caaccaaggt caaagaggaa ttaattcact tgtccacagg
    18721 tgacaacaat gaattggccg ccattatcaa attatcaggc agcttgggct tagctcacca
    18781 aagccttcat ttatccatta ctactgaaaa tgctaaaatt gcccgctaca tttattctct
    18841 tattgaagac gcctatgtta tcgtgccaga aatcaggtat catcaaaaga cgaacctgcg
    18901 caaaaaccgt gtttacaccg tctatgttga gcaaggtgtg gaaaccattt tagccgattt
    18961 gaaattagcg gactcctttt ttggtctgga aacaggcatc gaacctcagg ttttatcaga
    19021 cgataatgct ggccgttctt atcttaaagg ggcttttcta gcggcaggta gcatcagaga
    19081 tcctgagtca ggcaagtatc agttagaaat ctattcagtt tatcttgatc atgctcaaga
    19141 cttagctcaa ctcatgcaaa aatttatgct agatgccaaa accattgagc ataaaagcgg
    19201 tgcagttact tatttgcaaa aggcagaaga tatcatggac tttttaatta taattggtgc
    19261 catgtcctgc aaagaagact ttgaagccat caaattactt cgagaagctc gaaatgatat
    19321 taaccgtgcc aataatgcag aaacagctaa tattgccaaa actatcagtg ctagcatgaa
    19381 aac
//
LOCUS       DAUCXI010000034        19219 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.034, whole genome shotgun sequence.
ACCESSION   DAUCXI010000034 DAUCXI010000000
VERSION     DAUCXI010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19219
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.034"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            51..488
                     /locus_tag="VGY43_001317"
     CDS             51..488
                     /locus_tag="VGY43_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ4302497.1"
                     /translation="MIAIIVMGHGHFASGIVSSLELIAGPQEKVTAIDFTAEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGATDDELGGI"
     gene            488..1687
                     /locus_tag="VGY43_001318"
     CDS             488..1687
                     /locus_tag="VGY43_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEQ4302498.1"
                     /translation="MTRSLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTPEAREAALKAADKLVQRYQDKGGFIQ
                     AWGELGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPVKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFLNRLPKDQVSYWDLIFGDGSEQSRDSSATAIAVCGIHEMLKTLPDHDPDKKIYE
                     AAMHSMLRALIKDYANKDLKPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            1723..2211
                     /locus_tag="VGY43_001319"
     CDS             1723..2211
                     /locus_tag="VGY43_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ4302499.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQNIFIVVKDLQDAKRLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHQVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            2230..3012
                     /locus_tag="VGY43_001320"
     CDS             2230..3012
                     /locus_tag="VGY43_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ4302500.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGMILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWSFAILGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            2999..3820
                     /locus_tag="VGY43_001321"
     CDS             2999..3820
                     /locus_tag="VGY43_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ4302501.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYSNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFFPFITSLHLVMLENDRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPIFFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAVVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVLLTVLIGIIGSWLGILA"
     gene            3907..5814
                     /locus_tag="VGY43_001322"
     CDS             3907..5814
                     /locus_tag="VGY43_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEQ4302502.1"
                     /translation="MSLAFARFKETVNPDFCRNYLLDYQADSYADRKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQEAVTDDPEWNFMLNRQTYLQTLILVYLVERDERYL
                     LKAKSFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLSDALTKQEERLIL
                     ASLEKQLHFLHANYLDKYSLSNWGILQTTAILLADAYFGSDLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDFTDTRDILTLAATILEEPHLKAAAFPTLDIDSLLLLGEKGVHTFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSLCLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQIDSSWAYLSYPKSNYCHLRQNGHVYF
                     IEGSYQTQFSDRNNYQHDRQILILPPGILLIIDTIQAQGNHCLVSQFILDNHLDVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKFIKRKPFKDKGCTSTLLVPDDTKVTP
                     LTPLQTGKRNPIETALSWHLKGKQFDYSICVLQEDLIKGEKLVLLNGHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            5878..6873
                     /locus_tag="VGY43_001323"
     CDS             5878..6873
                     /locus_tag="VGY43_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEQ4302503.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRIKSTI
                     EATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(6957..9638)
                     /locus_tag="VGY43_001324"
     CDS             complement(6957..9638)
                     /locus_tag="VGY43_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEQ4302504.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQANERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGTLQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVQFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(9868..10254)
                     /locus_tag="VGY43_001325"
     CDS             complement(9868..10254)
                     /locus_tag="VGY43_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEQ4302505.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            10336..11637
                     /locus_tag="VGY43_001326"
     CDS             10336..11637
                     /locus_tag="VGY43_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEQ4302506.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDESLVTMTAALLHDIGHGAYS
                     HTFEALFHTDHEAFTQEIITNPETEINAILVRHALDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPLFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSQGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMIQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            12092..12901
                     /gene="yidA"
                     /locus_tag="VGY43_001327"
     CDS             12092..12901
                     /gene="yidA"
                     /locus_tag="VGY43_001327"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEQ4302507.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFMSRK
                     LGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            12901..14127
                     /locus_tag="VGY43_001328"
     CDS             12901..14127
                     /locus_tag="VGY43_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEQ4302508.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRAL
                     FVKIDPSLVIKQTLEGKESKENDVALSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLGIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLAAGKTRIPLAATLTLIYGESSENLYAGMDDNYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            14114..15349
                     /locus_tag="VGY43_001329"
     CDS             14114..15349
                     /locus_tag="VGY43_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEQ4302509.1"
                     /translation="MALIEISQEQFDHYCHSLVRHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELI
                     LKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTKQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(15448..16206)
                     /locus_tag="VGY43_001330"
     CDS             complement(15448..16206)
                     /locus_tag="VGY43_001330"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEQ4302510.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(16448..17644)
                     /gene="tuf"
                     /locus_tag="VGY43_001331"
     CDS             complement(16448..17644)
                     /gene="tuf"
                     /locus_tag="VGY43_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEQ4302511.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            complement(17998..>19219)
                     /locus_tag="VGY43_001332"
     CDS             complement(17998..>19219)
                     /locus_tag="VGY43_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEQ4302512.1"
                     /translation="ILSVIGLIMVYSTTSVSLIQAHANPFKSVINQGVFWIISLVAIT
                     FIYKLKLNFLTNTRVLTVVMLGEAFLLIIARFFTTAIKGAHGWIVIGPVSFQPAEYLK
                     IIMVWYLALTFAKIQKNISLYDYQALTRRKWWPTQWNDLRDWRVYSLLMVLLVAAQPD
                     LGNASIIVLTAIIMFSISGIGYRWFSAILVMITGLSTVFLGTIAVIGVERVAKIPVFG
                     YVAKRFSAFFNPFHDLTDSGHQLANSYYAMSNGGWFGQGLGNSIEKRGYLPEAQTDFV
                     FSVVIEELGLIGAGFILALVFFLILRIMNVGIKAKNPFNAMMALGVGGMMLMQVFVNI
                     GGISGLIPSTGVTFPFLSQGGNSLLVLSVAVGFVLNIDASEKRDDIFKEAELSYRKDT
                     RKENSKVVNIKQFQ"
BASE COUNT         5924 a         4129 c         3572 g         5594 t
ORIGIN      
        1 agcgctacaa tatttttaag taaaccggta aaccaaaaag gagttttatc atgattgcta
       61 ttattgttat gggacatgga cactttgcaa gtgggattgt ctcatcccta gagttaattg
      121 caggaccaca agagaaggta actgcaattg attttactgc tgagatgacc gccgctgatg
      181 tgcaggacca attatctcgt gctttaatcc cagaagagga aaccttagtt ctttgtgacc
      241 ttctaggagg tacccctttt aaagtcgctg caaccttaat ggaatctctt ccaaacacga
      301 cgtgtaatgt tctttctggc cttaacttag ccatgctgat tgaagctagt tttgcaagac
      361 aaacagcagc ttcttttgac gacttagtat caggacttat aacatgttct aaagaaggca
      421 ttgttgactg gaaaactctt tctcagcaag aagacggtgc gacagacgat gagttaggag
      481 gcatttaatg acacgatctt taaaaaccat tgctcttgaa cctatcaagc agcctgaacg
      541 atttaccaaa gaagactttc taagccaaga agacattact caggcccttg acttagccct
      601 caaacaagtt cggcttaaca tggactactt caaagaagat tttccaacgc cagctaccaa
      661 agataaccaa tacgccatta tggacaacac ggaatggacc aatgcctttt ggacaggttg
      721 cctttggtta gcttacgaat acagtgggga tgatgctatt aaagctctgg ctcaagcaaa
      781 tgacctttct ttcctagatc gagtaacaag agacattgag ctagatcacc atgatttggg
      841 ctttctttac accccttctt gcatggctga gtggaaactt ttaaaaacac ctgaggctag
      901 agaagctgct ttgaaagcag ccgacaaatt agtccaacgc tatcaagaca aaggcggctt
      961 tattcaggcc tggggagaac tggggaaaaa agaagattac cgtttaatca ttgattgtct
     1021 cctaaacatc caattactct tttttgctag ccaagaaact ggagacaacc gttaccgtga
     1081 catggcgatc aaccatttct acgcctcagc caatcatgtc atccgagatg acgcctctgc
     1141 ttaccacacc ttctactttg atccagaaac aggcgatcct gttaaagggg tcacccgaca
     1201 aggttatagc gatgattctg cttgggccag agggcaagct tggggcattt atggtattcc
     1261 tttgacctat cgtttcctaa aagaacctga actcattcaa ctcttcaagg gcatgaccca
     1321 ttatttcttg aaccgtcttc ctaaagacca ggtttcctac tgggatttaa tttttggaga
     1381 tggtagcgag cagtctcgtg atagttcagc aacagccatt gccgtgtgtg gtattcatga
     1441 aatgttaaaa accttaccag atcatgatcc tgataaaaaa atatatgaag ctgccatgca
     1501 cagcatgcta agagccttga ttaaggatta tgctaacaaa gatctcaagc ctggcgctcc
     1561 tctactactt cacggagtct attcttggca ctctggaaaa ggggttgacg agggaaatat
     1621 ctggggagac tattactatc ttgaagctct gcttcgtttc tacaaagact ggaaccctta
     1681 ctggtaacaa acaccgatac ctacatttaa aaaggagatt ttatgacaca accaaacatt
     1741 atcatgacgc gagttgatga gcgtttgatt cacggacagg ggcaattatg ggtcaaattc
     1801 ctcaactgca acaccgttat cgtcgctaac gatgcggttt ctgaagataa gattcaacaa
     1861 tccctcatga aaacagttat tccatccagt attgccattc gttttttctc cattcaaaaa
     1921 gtgattgaca tcattcataa agcaagtcct gctcaaaata tcttcatcgt ggtcaaagat
     1981 ttgcaagatg ccaaacgcct agttgaaggg ggtgttccca tcacagaaat caatatcggt
     2041 aatattcata aaactgatga taaggttgcg attacccagt ttatttcgct gggagaaaca
     2101 gacaagtctg ctattcgttg cttagcccat gaccaccaag tggtttttaa caccaaaaca
     2161 actccagctg gcaatagcgc ctctgacgtt gacatcttag attatattta atgaataaag
     2221 gagattgata tggatatcaa tttgttacag gcacttttaa ttggtctttg gacagccttt
     2281 tgtttcagcg gaatgttact tggcatctac accaaccgtt gtattattct gtcttttggt
     2341 gtagggatga tcttaggtga cttgccaact gcacttagca tgggagctat ctccgaatta
     2401 gcttatatgg gatttggagt gggtgccggt ggtaccgttc cacctaatcc tatcggccct
     2461 ggtatctttg gtaccttgat ggctattacc agtgctggta aagtcacccc agaagcggcc
     2521 ctagccttat caacaccaat cgcagttgcc atccaatttc ttcagacatt cgcctatacc
     2581 gcttttgctg gggctcctga aaccgctaaa aaacaattgc aaaaaggcaa tattagaggc
     2641 ttcaaattcg ctgctaatgg gaccatttgg tcttttgcta tccttggatt aggccttggt
     2701 ttattaggtg ccttgtcaat ggatactctc cttcacttag tggattatat cccacctgtc
     2761 ttgctcaatg gattgactgt cgctggtaaa atgttacctg ctatcggatt tgccatgatc
     2821 ttatctgtta tggccaagaa ggagttgatt ccttttgtac tgattggtta tgtttgtgcg
     2881 gcctacctcc aaattccaac catcggtatc gccattattg gtatcatttt cgccttgaat
     2941 gaattttaca acaaacctaa acaagtcgat gcaacaactg tccaaggagg ccaacaagat
     3001 gactggatct aataaattaa ccaagaaaga ttacctcaaa acagctctga gagctttctt
     3061 cctacaaaat gggtttaatt acagtaatta ccaaggtatc ggatacgcca atgtcatcta
     3121 tcctgccttg aaaaaacatt ttggcagtga taaaaagggc ttgtatcaag ctttagaaga
     3181 taactgtgag ttttacaata ccaaccctca cttctttcct ttcatcacca gtctgcactt
     3241 ggtcatgtta gaaaatgatc gtcctgaaga agaaacccga aacatcaaaa tggcacttat
     3301 ggggccttta gctggtatcg gtgactcctt atcacaattt tgcttagcgc cactcttttc
     3361 aacgatcgca gcttccttag ccagtgatgg tttagtttta ggtccaattt tcttcttcct
     3421 agccatgaat attatcctaa ccgctattaa aatcggttct ggtctctatg gctacaaggt
     3481 cggcacaagc tttattgata aactaagcga acaaatggcg gttgtgtcgc gcatggcaaa
     3541 tattgtcggc gttaccgtta tcgctggact agcggctact tctgttaaaa taactgttcc
     3601 cattactttt gcggctggca aggtggatgc ggccaataca gcacaaaaat ttgtgactat
     3661 tcaaggaatg cttgataaaa ttgctcctgc acttttacca gctctcttta ccttactcat
     3721 gtattacctt attaaaaaca aaaaatggac aacctacaaa ttggttctcc tcactgttct
     3781 tatcggtatt atcggtagct ggttaggtat tttagcttaa tggttcacag agacctgtta
     3841 tgagcatagg gaaatagttc ctaagcacat gatgaggtct cttttctttt ggaaaggaaa
     3901 tgtcctatgt ctcttgcttt cgcacgcttt aaagaaacag tcaatccaga cttttgcagg
     3961 aattacctgc tagactatca ggctgacagc tatgctgatc gaaaaaggat agctgaccta
     4021 ctcttaacca ataccttttt atttgaagat aattgggata tggagccctg ccacatccct
     4081 taccacttag atcccattac ttggcaagag gctgtcacag atgatcctga gtggaatttt
     4141 atgttaaatc gacagaccta tctccaaaca ttaatcctcg tctaccttgt tgaaagagat
     4201 gaacggtatc tcctaaaagc caaaagtttc atcctcaatt ggattgaatc agctattcct
     4261 ttagacccta aggggttagc tactagaacc ttagatactg gcatccgttg ttttgcttgg
     4321 gtcaaatgtt tgatttacct taatctttct gacgccttaa ctaagcaaga ggaaaggctc
     4381 atcctagctt ccctggaaaa acaacttcac tttctccatg ccaactacct tgataaatac
     4441 agtctcagca attggggaat cttgcaaacc actgcgattt tattagctga tgcctacttt
     4501 ggttctgacc ttgatattgc tgcagcaaca gctttcgcta gaaaagaatt gacgcaacaa
     4561 atcgcactcc aaattctcga agacggcagt caatttgaac aatcaaccat gtatcatgtg
     4621 gaagtactca aagcccttct ggaattaact gctctagtcc ctgattatct tccacagctt
     4681 agacctactt tgcttgccat gagtgattat ctcctcaaaa tgactggccc tgaccacaaa
     4741 cagatcccct taggagacag tgactttacc gataccagag atattctaac actagcagcc
     4801 actatccttg aagaaccaca cttaaaagct gctgcttttc ccacacttga tatcgatagt
     4861 cttctccttc taggagaaaa aggtgtccac acttttgaac agttacccgt ccaaacctta
     4921 ccaacttttg cgcatcactt tgaacattcc gggcacatta ccatcaatca agaaaattat
     4981 tatctttttt tcaaaaatgg gcccatcggt agttcccata cccatagcga ccaaaatagt
     5041 ctctgtctct attataaagg acaaccactt ttctgtgatg ctgggcgata cacttacaaa
     5101 gaagaaccat tacgctatgc cctaaaaagc gctagccatc attctaccgc cttcttagaa
     5161 gaacaattac ctgagcagat tgatagctcc tgggcttacc tttcttaccc caaatccaat
     5221 tattgtcacc ttcgacaaaa tggacacgtt tactttattg aaggtagcta ccagacgcaa
     5281 ttctccgata ggaacaacta ccaacatgac cgacaaattc tcatcttacc accaggaatt
     5341 ttgcttatca ttgatacgat acaggctcaa ggtaaccact gtcttgtcag tcaatttatt
     5401 cttgataatc acttagacgt aaagacagat caccttagtg acctcagact aatcagtgac
     5461 tgccctttca ctatcgaaga aacgattttg tcaaaaaaat acaaccaata cctgactagt
     5521 cacaaattca tcaaacgaaa accctttaaa gacaagggtt gcaccagtac cctgttagtc
     5581 cctgacgata ccaaagttac tcccttaaca ccacttcaaa caggcaaacg caacccaatt
     5641 gagaccgccc tttcctggca tttaaaagga aagcagtttg actacagtat ctgcgttctc
     5701 caagaggact taattaaagg agaaaaacta gttctcctaa atggtcataa aatcagagga
     5761 aaggtggttg ttatcaacca tatcacgaat gagattattc gattgaaaca ctaaatcttt
     5821 tacgagtcct tatgttataa tatgactaac cattactatt tttaaggagt gtatgcaatg
     5881 cagcgcaaag taaccatcaa agatattgct gaattagcga aaacttcaaa aacaacagtt
     5941 tctttctact taaatggtag gtttgacaag atgtctgaag aaactaaaaa ccgcattaaa
     6001 agcacgattg aagctaccaa ttataaacca agcattgctg ccagaagtct aaacgccaaa
     6061 tctactaaac tcattggcgt ggttattggt gatattacca atagtttttc caatcaaatt
     6121 gttaagggaa ttgaaagcaa agcccaggaa tttggttacc aaattatcat cggaaacagc
     6181 aactacgacc cttctcgcga agatgaactc attgaaaaga tgctgaacct cggagtggat
     6241 ggctttatca ttcagcctac ctctaatttc aggaagtatt ctcgcattat cgatattaag
     6301 aagaaaaaag tggtcttttt tgatagccaa ctttacgaac atcgcacaaa ctgggtcaaa
     6361 actaataatt atgatgctgt ttatgatacc attcaacaat gtatcgataa aggttatgaa
     6421 cattttatca tgatcacggg taaccccaat ttacttagca ctcgtattga acgcgcttca
     6481 ggcttcattg atgtgttaga agctaatcat cttactcatc aagaaatgat tattgatgaa
     6541 aatcagactt cttcagaggc aattgctcag tttttgcaag gatcactgac taaaaagagt
     6601 ttggtttttg tccccaattg ttgggctctt ccaaaagtat ttacagctat gaagtctctt
     6661 aaatttaata taccagagat tggactagta ggatttgata acattgagtg gacaaaattt
     6721 tcttcaccaa cactaacaac tattatccaa cccgcctatg aagaaggcga acaggctact
     6781 aagattttaa tcgatgatat tgaaggtcac agtcaagaag ccaaacaaca aatttttgac
     6841 tgtcaagtca attggcaaga atcaactttt taatgtcagg cataccaata gtccttatcg
     6901 ttgtaacgat tataaaaaaa ggtttgagac aattgtctca aaccttttag cgtctattaa
     6961 attgcttttt catcttgacc aagtgatcgt tgaacagctt tcaccaattc aacaagaaca
     7021 accatcaaga gacttccgat aataaccact aaccattgtg tgatcgtcaa gtgtgtcaca
     7081 tggaagaatt gattaaatcc aggaacaaca actgttgcca tcaatgctac aaaggccact
     7141 ggaatagaat agttgaacaa tttgtttttg aacaacccaa cagtaaagat ggattggtaa
     7201 acagatttca cgttgtaggc atgtaccaac tgaatcaaac cgagggtcac ataagccatg
     7261 gtcaaggcat ctgcatggac atcatggtag cttgtgtgtt ctgggaacat caaggcaaaa
     7321 ccataaaccc caagcaccaa aatggtttgg aaggcacctt ggtaaagaat ggcttccttc
     7381 accccaccat caaagaagct tgacttacgt ccacgaggtt tgtgtttcat cacaccaggc
     7441 tcagcaggtt caacaccaag agcaatagct ggtagggtat cagttaccaa gttaatccaa
     7501 agcaagtgaa ctggttgaag cacatcccaa ccaaacaagg ttgcaaggaa gatggtaaag
     7561 acttctgcca tgttagcaga aagtaagtat tgaattgttt tttgaatatt tgagaagacc
     7621 ttacgtcctt cttcaaccgc aacgataatg gttgcaaagt tatcatcggc aagaaccatg
     7681 tcagaagctc ccttagaaac ctctgtacct gtaattccca taccaatacc aatatctgcc
     7741 gttttaagag atggtgcatc gttaacccca tcgccagtca tggcaacaac tttgccttca
     7801 ttttgccaag ccttaacgat acgaacttta tgctcaggag atacacgggc atacacagag
     7861 tattgtttaa agactttttg gaactcttca tctgataatt cgttgagttc agcacctgta
     7921 aagacatgat caacgccatc ttcttcgata ataccaagac gtttcgcaat agcttttgct
     7981 gtatcttggt ggtcaccagt aatcatgatt ggacgaatgc cagcttcctt agctacttta
     8041 acagcctgtg ctgcttcagg acgttcaggg tcaatcatcc ctaccaaacc agagaagaca
     8101 agattagcct caacaatttc tgtttccagt gttggaagag catcagaata tttgtaagcc
     8161 atcatcaaga cacgaagagc ttgtttggca agactcttat tggtatcaag aatggttttt
     8221 ttatcagcat ccgtaatagg acgaatttgt ccattttctt caatctgtgt gacacgcttc
     8281 aacaattggt ctggcgcacc tttaacagcg atgaaatatt tgccatcagc ttgtttatga
     8341 atagttgaca tcaacttacg gtcagaatca aatggtaatt ctgccacacg aggttctgcc
     8401 accatagcct cacgtacgtc aaaattgtgg tctaacccaa actgtaccaa agctgtttct
     8461 gttgggtcac caattaactt ccctgaagga tcaactttag tatcattagc aaagttcatt
     8521 acacgaagtg tcgtattgtc aaaagcaata tcagctgatg aactttggag tgtcccgttg
     8581 gtataaactt tttcaacggt catttgattc attgtcaagg tacccgtttt atcagaagca
     8641 atgatttcag ttgatcctag cgtttcaaca gctggtaatt tacggataat ggcgttacgt
     8701 ttagcaagta cttgagttcc aagagaaagc acaacagtaa caatcgcagg aagtccctct
     8761 ggaatagctg caacggcaag cgctactgaa gtcatcaagc cttcaagcgg gtgttgacca
     8821 cgcaagaaga ctccaacagc aaaagtcacc gctgcaatca caaggatcgc ataagtcaaa
     8881 atcttagaaa gattgtcaag gttttgcttc aatggtgtat ctgtctcatc agcattagca
     8941 agcataccag caatatgccc aacctcggtg tacataccag tgttagtgat aaccccaatc
     9001 ccacgaccat atgtcacatt tgagttttga tatcccatat tgacgcgatc accaataccg
     9061 gcatcttctg aaacagccgt tgacaagtct ttttcaaccg gtacagattc tccagtaagc
     9121 gctgcttctt cgatttttaa ggagttagct tccaaaagac gcagatcagc agggacaaca
     9181 tctcccgctt ctagcaagac aatatctcca gggaccaatt ctttagagtc tatctcagtc
     9241 acatgcccat cacggcgaat acgagccagt ggacttgaca ttgatttcaa ggcttcaata
     9301 gcagcttcag cttgtccttc ttggtaaaca ccaaaagcag catttaggat aacaacagcc
     9361 aagataataa tggcgtctgt caaaccttcc atcccctctg taagaactga aagaagggct
     9421 gccacaatca aaataataat catcaaatcc ttaaattgat caaggaattt cataaataaa
     9481 cttcgttttt cgccttcatc aagctcatta cgaccatact ctgctaagcg ctcgtttgcc
     9541 tgggcagacg taagaccttc gcgactggtc tctaattgag ccagtacggt ctcttcactt
     9601 tgcgtgtaaa atgcttcatg tctttgttct ttagacaaat tagtacctcc ttggtctttt
     9661 tattttagtt gttcaaataa aaagacctgt ttattttctt aaacaagtct cgctgtttaa
     9721 gattgtaccg gaaaccgaaa ttccgtattg acgatacaat cacggctagc cgtctgctac
     9781 tcccttgata taataaccat tatagtaaaa acctgactaa aaaacaagaa taatccctaa
     9841 tcagatgatt tactgctatc tttttagtta atcccaactc agctcaagat gatagcttgc
     9901 aaatagcatt tctgtttgag cttgaagcaa atgataatga aggtccaatt tttgacaaga
     9961 acaatctaag tggtaatgac tggtatctgt caaaaattgt tgaaccccca tcggtgtagg
    10021 tagagcaatc aggaccttct tgcccgcaaa aaatttcatg attgactgag ggttggaaaa
    10081 acggctcatg gtcagttctg tctcattgta cttgatgaca accttttcct tgtcagtgtt
    10141 ttgatagatg aggtactgat agcccccttt ttctcgccac tcacaatcat gaatttcttg
    10201 aataatctct gtctcatctc caaagcgaat atggttggtt aactgtaatt tcataactct
    10261 tctttctatt ctaagctcgt ctgtttattc tatcaatttc tccttatttt atcaattttt
    10321 gatataataa aaattatgaa tgaaaaagta tttcgtgacc ctgttcacaa ctatatccac
    10381 attgataatc cattaattta tgaccttatc aataccaaag aattccaacg cttacgacgc
    10441 atcaaacaag tccctacaac agctttcacc ttccacggcg cagaacatag ccgtttttct
    10501 cactgcctag gtgtttacga aattgcccgt cgggtgacag ctatttttga agagaaatac
    10561 gctgatatct ggaataaaga tgaaagtctg gtcactatga cggctgccct cttacatgac
    10621 attggtcatg gagcctattc tcataccttt gaggcccttt tccatacgga tcacgaggcc
    10681 tttactcagg agataattac caatcctgag acagaaatca atgccatttt ggtgcgtcat
    10741 gctcttgatt ttccagacaa agttgccagc gtgattaatc atacctatcc taacaagcaa
    10801 gttgtgcaac tgatttccag ccagattgac tgcgaccgta tggattacct tttaagagat
    10861 tcttattttt ctgctgccaa ttatggtcag tttgatttaa tgcgcattct acgtgtgatt
    10921 cgacctgttg aagatggcat tgtctttgaa catagtggta tgcatgctgt cgaggactat
    10981 attgtcagtc gttttcaaat gtacatgcag gtctattttc atcccgccag ccgtgctgtt
    11041 gagctcatct tacaaaatct cctcaaaaga gcccaacact tatatcctga gcaacaggct
    11101 tatttccaaa aaacagctcc tggactcatc cccctctttg aaaagaaggc taatttagca
    11161 gattatatag ccctagatga cggagtcatg aatacttact tccaagtctg gatggcaagc
    11221 gaagaccata tcttatcaga tttggccagt cgctttatta atcgaaaaat tctgaagtct
    11281 gttacctttg accaagattc ccaaggagag ttagaacgct tgcgccaatt ggtcgaatca
    11341 gttggctttg atccagatta ttacaccggt atccatatca acttcgacct gccttatgat
    11401 atttatcgac cagagctcga aaatccaaga actcagattg aaatgataca aaaagacggg
    11461 agccttgctg aattatctca gttatctcct attgtcaaag cattaacagg gacaacctac
    11521 ggagaccgtc gcttttattt tccaaaggaa atgttagagc tcgatgacct ctttgctcct
    11581 agcaaggaaa cttttatgag ttatatttcc aatgggcatt ttcactttag tcagtaaagc
    11641 cctttaagat tgcagaaaaa gtcttttttg atacttttct taggtgatgc ttatggcagc
    11701 gacttccttt ggaattctat gctttatttt tgagcctggg gtctcaaaaa ttccgcgtaa
    11761 cgtcactgcc agtattgaca ccacttttgc cacagcaaaa agcagctgtt ttggctcacg
    11821 tcacacgcag aaataagaaa tcagttgtca aatcagcaga gcagttcatg ctttttgagc
    11881 atcaaactgg gtttgtctcc attctaagat tgaagaaaga gtactttctt caatcttttt
    11941 agttactaca gaggcgattg agctaaacta aaacgttttc tctcgttttt ccttaagttt
    12001 cctttcccat cccatgacaa aagcaccgat ttttagtaag ataggaggga gaacaatttt
    12061 aagataaacc acaaaaaaca aggaggatgc catgtctatc aaactggttg ctgtcgatat
    12121 tgatggcaca ttactcactg atgaccgtcg aattacagat gatgtttttc aagctgtcca
    12181 agaggctaaa gcccaaggtg ttcatgtggt gattgctact ggccgaccta ttgccggagt
    12241 gatttcatta ctcgaacaat tagaactcaa ccacaaagga aaccacgtta tcacttttaa
    12301 tggtggcttg gtgcaagatg ccgagaccgg cgaagaaatt gttaaagaat tgatgactta
    12361 cgacgattat ctggaaacgg aatttatgag ccgaaaatta ggagttcaca tgcatgccat
    12421 taccaaagaa ggtatttaca ctgccaatcg gaatattgga aaatacacag ttcatgaatc
    12481 gactttggta aacatgccta ttttctatcg cactcccgaa gaaatgacca ataaagaaat
    12541 catcaaaatg atgatgattg atgaacctga ccttttggac gcggccatca agcaaattcc
    12601 tcaacatttc tttgataagt acaccatcgt caagtcaacc cctttttatt tagagttcat
    12661 gccaaaaacc gtcagcaagg gcaatgccat caaacactta gctaaaaaac tcgggctaga
    12721 tatgtcacaa accatggcca tcggggatgc tgaaaatgat cgtgctatgt tagaagtcgt
    12781 tgccaaccct gttgtcatgg aaaatggggt tcctgaattg aaaaaaatag ccaaatacat
    12841 caccaaatcc aacaatgaca gtggtgtggc acatgctatt cgcaagtggg tattaaacta
    12901 atgtatacat ataaaatcgg aatatctcct gaagaacatg atcagtttgt cttagcacag
    12961 ccacaagctg gcttacttca aagttcaaag tggggaaaag tcaaagataa ctggaaacac
    13021 gaacgcatca gcttttatga aaatggggta caagttgctg ctgctgcttg tttaatcaga
    13081 aaacttcctc ttggtttcac tatgatttat atcccacgtg ggccaatcat ggactacgcc
    13141 aattttgaac tccttgattt cgtcattaaa acgctcaaaa ctttcggaaa aagcaaacga
    13201 gcgctttttg tcaaaattga tccaagttta gtcatcaaac aaactttaga aggaaaagag
    13261 agcaaagaaa atgatgtggc cctctctatt attgcttttc taaaaaaact tggtgtcgaa
    13321 tggtctggca gaacaaaaga actcgaagac actattcaac caagaataca agccaacatc
    13381 tacgccaagg attttgactt tgacagcctg cccaaaaaag ccaagcaatc cattcgtacc
    13441 gctaccaata aaggtgttaa tgtcacgatt ggtggcagtg aattgctaga cgacttttca
    13501 gccttgatga aaaaaaccga gaatcgaaaa ggcattatcc ttcgaggcaa atcctactat
    13561 caaaaattac taggtattta tgctggtcag tcctacatta ctatggctag tttagactta
    13621 cctgaacaaa aaaaactctt gatccaacag ttggacaaag ccttagcaga acaagcacga
    13681 ttaacagata agagtaaacc tagcaaagta gcagaaaatc aaaaaaccat tgcacggcta
    13741 caaaaagatt taaccatttt aagcgagcag ctcgctgcag gcaaaacccg catcccacta
    13801 gccgccaccc taaccttgat ttatggcgag tcttctgaaa atctttatgc gggaatggac
    13861 gataattatc gcaattatca agctcctctt ttaacctggt atgaaacggc taaagaagct
    13921 tttaaaagag gctgccgctg gcataattta ggaggcgtgg aaaatcaaca agatggtgga
    13981 ctctatcatt tcaaagctag actcaacccc accatcgaag aatttgcagg tgaattcaac
    14041 attcctgtcg gccttgtttc aagcttagcc atcttgacct ataacttaag aaaaaaatta
    14101 aggagcacaa ctaatggcac taattgaaat ttcacaagaa caatttgacc attactgcca
    14161 cagtctcgtc cgtcattcct ttatccaaac ctcagaaatg gccagcttga tggctaaaag
    14221 aggggcaaaa ccacaatttc ttggacttga aaaagatggt gaactaaagg ttgctgctat
    14281 ggtatttagc caaaaagtgg ctggaggttg gcgtatggaa ctcaatgcag gccctaatac
    14341 caatcatccc gaagaattag aacattttta cactcaactt aaagactatg ccaaacaaaa
    14401 agacgttatc gaactcattt taaaacctta cgacaattat cagtcatttg atactgatgg
    14461 catccctatt tctcatccaa acactgacct tattagcctt ttaacggcgt taggatataa
    14521 acatgacggt ttaaaaacag gctatcctga gggtgaacct gtttggcatt acgttaaaaa
    14581 gttagaagga attgattcct cacgtttaac ccattccttc agcaaaaaag gaaaagcttt
    14641 aataaaaaaa gctaatactt ttggtattaa attacgtcaa ctgaaacgag atgagttaca
    14701 ccatttcaaa gaaatcactg aagcaacctc tgatcgtaga gattaccttg acaaatcatt
    14761 atcttactat caggactttt atgatagttt tggagactct tgtgaattta tggttgcaac
    14821 tcttaatttt gaagattacc ttaataacct taaacaaaga caactacaac tagcaaccag
    14881 catcaacaaa gttaaaggag accttggcaa aaatcctcat tctgaaaaaa agcaaaatag
    14941 attaaaagaa ctatccagcc aattcgaaac ctttcaggta agaatttctg aagctctcca
    15001 ttttcttgaa gagtacggaa ctaaagatgt gttccttgcg ggaagtcttt ttatctatac
    15061 caaacaagag gccgtctacc tcttttcagg atcttacccc aaatttaata aattttatag
    15121 cccagctcta ttacaagagc atgctatgct caaggcaatt cacaagggca tcaaacaata
    15181 taattttctt ggtattactg gaaaatttga tggttcagac ggtgtcttgc gctttaaaca
    15241 gaatttcaat ggctttattt tgcaaaaacc aggaacattt agatgttatc catttccaat
    15301 caaatatcat ttcattagat tggcaaaaaa gctattaaac cgctattagg ctaatgcatt
    15361 tgcctgtaga atcaccttta ttctctcata gtaagagtta agtcatctaa aaaagaaaag
    15421 gatttaacct tttctttttt agatgactta gttaaggaaa tcaagcaaag caaggaagct
    15481 atcagcttca agtgatgcgc cacctacaag ggcaccgtca acatctggac aagccatgta
    15541 atctttaacg ttttcaggtt ttacagaacc accgtattga acgcgaactt tatcagcaac
    15601 ttcttgccca aagtctgctg ctaccacgtc acgaacagct ttacacatgt tttgagcatc
    15661 atcttgagta gctgatttac cagtaccgat agcccagatt ggctcataag ctaaaacaag
    15721 tgaagctact tgctctgctg aaagacctgc aagtgctgct gaaacttgtg cacctacaaa
    15781 ctcaacggct ttaccagctt cataagtttc aagagactca ccacaacaaa caattggagt
    15841 taaaccgtta gcaaagattg ctttggcttt tttattaatg tcttcatctg tttcatggaa
    15901 gtaatcacgg cgttctgagt gaccaatcac aacatagtca gctcccattt cagcaagcac
    15961 ttttggtgat gtttcaccag tgaatgcccc tgtgttttca aagtagcagt tttgtgcagc
    16021 aactttaaga actgaatctt tagcagcttc aatagtggtt accaaatcaa cagctggggc
    16081 tgctacggca acatcaacaa ggtcagttga aggtaatttg cttgctacag cctcaacgaa
    16141 tgcttttgct tcttgagggt ttttgttcat tttccagtta ccagcaataa ttggtttacg
    16201 tgacatatca catacctctt ctttttttta tttatatctt ctattttagc acaaatgacc
    16261 gacgattaaa aggaattgct tatattttag gaatattttc acaaataaaa actctttttc
    16321 tgaaagcttt tcattcttat ttatcagcat tttatggagt ttaagatagc aaaaagcccc
    16381 cgaattgggg gcttcttcaa acttaagttg tctgacttaa attgctattc tgggaactta
    16441 attaaaatta agcttcgatt tctgaaacga tacctgaacc aacagtacgt ccaccttcac
    16501 ggattgagaa agtagtacct tgttctacgg caattgggtg gatcaactca acgttgattg
    16561 tcacgttatc accaggcata accatttctg tacctgctgg aagttcgatt gaacctgtta
    16621 cgtcagttgt acggaagtag aattgtggac ggtagttgtt gaagaatgga gtgtgacgtc
    16681 caccttcgtc tttagaaagg atatatactt cacctttgaa tttagtgtgt gggttgattg
    16741 aacctggttt agcaataact tgaccacgtt cgatttcgtc acgttgaaca ccacgaagaa
    16801 ggatacctac gttgtctcct gcaagacctt cgtcaagttg tttacggaac atttcaacac
    16861 cagtaacaac agctttttta gtttcttctt tgataccaac gatttcgatt tcgtcgttga
    16921 cacgaacagt accacggtcg atacgtcctg aagcaactgt accacgacct gtaattgaga
    16981 atacgtcttc gactggaaga agcaatggtt tgtcagtgtc gcgttctggt tctggaatgt
    17041 atgaatcaac agtatccatc aattccatga tgatgtcttc aaatttagtg tcgccttcaa
    17101 gagctttaag agctgaacct tggataactg gaaggtcatc acctgggaaa tcgtattctg
    17161 aaagaaggtc acgaatttcc atctcaacta attcaagcaa ctcttcgtca tcaacaaggt
    17221 caactttgtt catgaacacg ataaggtgtt taacaccaac ctgacgtgaa agaaggatgt
    17281 gctcacgagt ttgtggcatt ggtccatctg ttgaagcaac tacaaggata gctccgtcca
    17341 tttgagcggc accagtgatc atgtttttaa cgtagtccgc gtgtcctgga gcgtcgatgt
    17401 gcgcatagtg acgagttgca gtttcgtact caacgtgtgc agtgttgata gtgattccgc
    17461 gttcgcgttc ttctggagca gcatcgatag aagcataatc ttttggttgg ttaactgatg
    17521 aaggcaagcg acgtgccaat acagttgtga ttgcagctgt taaagtagtt ttaccatggt
    17581 caacgtgtcc gattgtacca atgttaacgt ggggtttact acgatcgtat ttttcttttg
    17641 ccattttagg aaaagcctcc aataaaatat attttataga tagacggtag gccatacagt
    17701 ctaactttac cttactattg tagcaaatta caatgaaaat gcaagtattt tatgtttttt
    17761 gccatttctt tattttttaa atagaagaaa aagtcttttt cgatactctc cttaggtggt
    17821 gcttatagca gcgacttcct ttggaattcc acgccttatt tttgccacag caaaaagcag
    17881 ctgtttgggc tcatgtcaca cgcaaaaata agaaatcagc agagcagttc aagttttttg
    17941 agcatcaaac tgggattgtc tatattctaa aatctcctta aaggagattt tagaatatta
    18001 ttgaaattgc ttgatattta caactttact attttctttt cgagtgtcct ttcgataaga
    18061 taattcagct tctttaaata tatcatctcg cttttcgcta gcatcaatat ttagtacaaa
    18121 acctactgca acagataaga caagtaagct atttccacct tgagacaaaa aagggaaggt
    18181 aacaccagta gatggaatta agcctgagat accaccaata ttaacaaaga cttgcatgag
    18241 catcataccg cctactccta aagccatcat ggcattaaaa ggattttttg ctttaatacc
    18301 aacattcata atacgtaaaa ttaagaagaa aacaagtgcc aaaataaacc ctgctcctat
    18361 tagacctaac tcttcaatga caactgaaaa gacaaagtct gtctgtgctt cgggcaaata
    18421 gccacgcttt tcaatggaat ttcctaaccc ttggccaaac cacccaccat tactcatagc
    18481 atagtaagaa ttggctaatt ggtgacctga atcggtcaag tcatgaaaag gattaaaaaa
    18541 ggcactaaaa cgtttagcga catagccaaa aacaggaatc ttagcaactc tttctacccc
    18601 aataacggca atagtcccaa gaaagaccgt ggatagaccg gtaatcatga ctaggatagc
    18661 cgaaaaccat cggtaaccaa tgccactgat agaaaacata ataatggctg tcaatacaat
    18721 aatggaagca tttcccaagt caggctgagc agcaaccaaa agtaccatca acaaagaata
    18781 aacacgccag tcccgtaaat cgttccattg tgttggccac cattttcgac gagttagtgc
    18841 ttgataatca taaaggctaa tgtttttttg gatcttagca aaggtcaatg ccaaatacca
    18901 taccataatg atctttaaat actcagcagg ctgaaagctg actggtccga tcacaatcca
    18961 accatgcgct cctttgatag cagttgtaaa gaagcgggca ataattaaaa gaaaggcctc
    19021 tcctaacata accacagtta atacccttgt attcgttaaa aaatttaatt ttaatttata
    19081 gataaatgta atagccacta gacttattat ccaaaaaact ccctggttaa tcaccgattt
    19141 aaatggatta gcatgtgctt gaatcaagct gacacttgtg gttgagtaaa ccattattaa
    19201 gcctatcacc gataaaatt
//
LOCUS       DAUCXI010000035        18196 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.035, whole genome shotgun sequence.
ACCESSION   DAUCXI010000035 DAUCXI010000000
VERSION     DAUCXI010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18196
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.035"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            42..1093
                     /locus_tag="VGY43_001333"
                     /pseudo
     CDS             42..1093
                     /locus_tag="VGY43_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
     gene            complement(1174..2340)
                     /locus_tag="VGY43_001334"
     CDS             complement(1174..2340)
                     /locus_tag="VGY43_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEQ4302513.1"
                     /translation="MKNQLGQLALEQAKTFGGKLEVQPKVDIKTKHDLSIAYTPGVAG
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALAPTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLQKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEAAQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYPDEALEAGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPDDALSTTNIIPDAFKEGVAEIVAKSVRSVVLKS"
     gene            complement(2372..3703)
                     /locus_tag="VGY43_001335"
     CDS             complement(2372..3703)
                     /locus_tag="VGY43_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEQ4302514.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLTVYLVLATLILVTG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHTSYSGQGQLVKIGHSEDMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTGFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKEVVATLSWQYFIVVISVVLTVVSVGFFVSRFLNMNPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            3864..5405
                     /locus_tag="VGY43_001336"
     CDS             3864..5405
                     /locus_tag="VGY43_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ4302515.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTHPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLLLCLLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKAGILQLCNQAGQKLIARKCQLGKPTGNSFNHLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSATKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSKFHQHQTVTELQFSVTTPYVGGQH
                     ERFNH"
     gene            5386..6051
                     /locus_tag="VGY43_001337"
     CDS             5386..6051
                     /locus_tag="VGY43_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEQ4302516.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKWRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQLLEKGLSEST
                     FQWIMENIKAFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(6106..7179)
                     /locus_tag="VGY43_001338"
     CDS             complement(6106..7179)
                     /locus_tag="VGY43_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ4302517.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDGIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(7172..7948)
                     /locus_tag="VGY43_001339"
     CDS             complement(7172..7948)
                     /locus_tag="VGY43_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302518.1"
                     /translation="MKKFANLYLTSVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            complement(7945..8739)
                     /locus_tag="VGY43_001340"
     CDS             complement(7945..8739)
                     /locus_tag="VGY43_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302519.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMIAIMWLTKEKSK"
     gene            complement(8723..9877)
                     /locus_tag="VGY43_001341"
     CDS             complement(8723..9877)
                     /locus_tag="VGY43_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302520.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL"
     gene            complement(9923..10810)
                     /gene="murB"
                     /locus_tag="VGY43_001342"
     CDS             complement(9923..10810)
                     /gene="murB"
                     /locus_tag="VGY43_001342"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEQ4302521.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYANKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTSSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHAGFMINVADGTAKDYEDLIAYVIETV
                     ENHSGVRLEPEVRIIGENL"
     gene            complement(10960..11460)
                     /gene="folK"
                     /locus_tag="VGY43_001343"
     CDS             complement(10960..11460)
                     /gene="folK"
                     /locus_tag="VGY43_001343"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEQ4302522.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            complement(11457..11816)
                     /gene="folB"
                     /locus_tag="VGY43_001344"
     CDS             complement(11457..11816)
                     /gene="folB"
                     /locus_tag="VGY43_001344"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEQ4302523.1"
                     /translation="MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGGKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            complement(11832..12623)
                     /gene="folP"
                     /locus_tag="VGY43_001345"
     CDS             complement(11832..12623)
                     /gene="folP"
                     /locus_tag="VGY43_001345"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEQ4302524.1"
                     /translation="MKIGRFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCRFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWIDPGFGFAKSVQQNMELLKGLDRVCQLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLS"
     gene            complement(12632..13216)
                     /gene="folE"
                     /locus_tag="VGY43_001346"
     CDS             complement(12632..13216)
                     /gene="folE"
                     /locus_tag="VGY43_001346"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEQ4302525.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            complement(13251..14528)
                     /locus_tag="VGY43_001347"
     CDS             complement(13251..14528)
                     /locus_tag="VGY43_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEQ4302526.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYP
                     RLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTGFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRRYWKKHIEKNVLLTH"
     gene            14859..15821
                     /locus_tag="VGY43_001348"
     CDS             14859..15821
                     /locus_tag="VGY43_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ4302527.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSQFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMSPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEMGSAANLTLKQMKEMKQFGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            complement(15938..17173)
                     /locus_tag="VGY43_001349"
     CDS             complement(15938..17173)
                     /locus_tag="VGY43_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEQ4302528.1"
                     /translation="MIKRWVILFFMVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSELHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDNRYPGSALEEENTLSAQDVAVVTMHLLEDFPEILEITKQTEVNFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRVITVILNADGSDKN
                     QNTRFEQANRLLDYVARTYCRRKILKKGSLVSERSLPIQDGQVKELPVSVAEDVTIIL
                     QQGEQVPKPKQFMISETSLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(17331..18196)
                     /locus_tag="VGY43_001350"
                     /pseudo
     CDS             complement(17331..18196)
                     /locus_tag="VGY43_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106750.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
BASE COUNT         5723 a         3901 c         3164 g         5408 t
ORIGIN      
        1 tgaattggtt gattacctct caaccttata aagagttaaa tatgaaagca gcaacttacc
       61 tttcaaccgg aaatctacag ctcatagaca aaccaaaacc agtcattata aagcctacag
      121 atgctatcgt ccagttggta aaaaccactc tatttgtgga actgatttgc atatcttagg
      181 tggggatgtt cccgcatgta aagaaggaac aatccttggt catgaaggaa ttggaattgt
      241 taaggagatc ggtgatgcgg tcactaactt taaaatcgga gataaagtga ttatttcttg
      301 cgtcacatca tgtcatacct gttattattg taaacgaggc ctttcgtcac attgtgaaga
      361 tggcggttgg attcttggcc atttaattaa tggaacacaa gcagaatatg tccatatccc
      421 acatgcagat ggtagtctct atcatgctcc tgatacgatt gatgatgagg cactggtcat
      481 gctttctgat attttaccaa cttcatatga aattggtgtc ttgccatcac atgtcaagcc
      541 tggagataat gtttgtatta ttggtgccgg tccagtagga ctcgcagccc tactaaccgt
      601 tcaacttttc tctccagcca atattattat ggtcgactta tctcaaaatc gccttgaagc
      661 agctaaaacg tttggagcca cacacacgat ttgttcagga agtagtgaag aagtcaaggc
      721 tatcattgac gatataacca atggacgtgg tgtcgatatt tccatggagt gtgttggtta
      781 tcccgcgaca tttgatattt gccaaaaaat tatatcagta ggtgggcata ttgctaacgt
      841 tggggttcat gggaaaccag ttgatttcaa cctggatgaa ttatggatta aaaatatcac
      901 cttaaacact ggacttgtta atgccaatac aactgaaatg ctactaaatg tcttgaaaac
      961 tggaaagatt gacgcaacaa gacttattac acattatttt aaactttcag aagttgaaaa
     1021 agcttatgaa acctttaaac atgctggtgc aaataacgcc ttgaaagtta ttattgataa
     1081 tgatattagc taatcacaaa ataagtagaa gctagaaata cgcttctact tattttgtga
     1141 tttaaagtat aactttctct tttttcatat attctatgat ttaaggacta ccgacctgac
     1201 gcttttagcg acaatctcag cgactccttc tttaaaggca tctggaataa tattagtagt
     1261 gctcaaagcg tcatctggga caagactggc aatacctttt gcggcagcaa tttgcatctc
     1321 aacagtaatg gtttttgccc gtgcatctaa tgctccccta aaaatacctg gaaaggcaag
     1381 gacattatta atctggttag gaaaatcact gcggccagta cctacaatgt aagcccccgc
     1441 ttcaagggct tcatcagggt aaatctctgg aatagggttg gccatggcaa aaattactgg
     1501 gcgcgctgcc attttactaa tccactctgc ttttaagact cctggtgctg atacgccaat
     1561 gaagatatct gctccttcaa gagcatcttc taaggtacct gatttaaact cacgattagt
     1621 gactttcgct atatccaaat gatgtggcgc taattgagcg gcttcttgtt cattgataat
     1681 gccaaattta tccactactg tcactttcgt agcacctgct gctaataatt tacgggtaat
     1741 ggataatccc gcagatccac caccgttcac cacgatggat acctcatcaa gggatttttg
     1801 aagaagtttc aaactattaa agatggctgc taacaccaca atagctgttc catgctgatc
     1861 gtcatggaaa acaggaatat gacattcctt aattaagcgt tgctcaattt caaaacagcg
     1921 gggcgcacta atatcctcta aattaatacc accaaaggtt ggtgcaagcg ccttgacaat
     1981 actaataatt tcttcagtat ctttggtatc taatacaatc ggaatagcat cgacacctgc
     2041 aaatgcttta aaaagggctg cttttccttc cataactggc atggctgctt cagggccaat
     2101 atcccccaga ccaagaaccg cagtaccatc actgataacg gctactgtat ttttcttggt
     2161 ggttaagtca tatgctaatg ttttatcttt tgcgatggca gatgacacac cagctacacc
     2221 tggtgtatag gcaatgctca aatcatgttt agttttaatg tcaacttttg gttgaacttc
     2281 caatttaccg ccgaacgttt tagcttgttc aagggcaagt tgacctaatt gatttttcat
     2341 aggaaatacc tctctttttt attggtttgg attaactaaa aataattctt aaaatagctg
     2401 tcatggtgat aacggtaatg gccccgccta gacgagtagc gacttgggca aacggcatta
     2461 gattcatgcg gtcagccgta ctcaaaatag ccacgtcccc tgttccaccc ataccacttt
     2521 gacaagctga aataatagct gcttccactg ggttcatgtt aaggaaacga gagacaaaaa
     2581 aaccgacact gacaaccgtt aacaccacac taatcaccac aataaaatat tgccagctaa
     2641 gggttgccac aacctctttt aaggggatat aaagcagacc aagccctgcc attaacggaa
     2701 aagtaaagtt gctggaaata aatttataaa gttgtttggc accattttgg gtttcttggg
     2761 gaataacatt caggtatttc aagaaggctg ccagaataat catcaacacc ggtcctggaa
     2821 aacctgttaa atgctgtaac aagccaccag caataaaaag tgaacaagct gttaaaacgc
     2881 ctgcccccat taatttaaca tctagggctc cagaattgtc ttttagggca tcagacatgt
     2941 cttcgctgtg accaatttta accagttgcc cttgaccaga ataacttgtg tgcttctctc
     3001 caaaacgatt gagcaaagcc gtgcacaaga tagcaaagaa attcccaata atggtggctg
     3061 gaatcagttg agccactaat tgctcacttc cgactcctgt aatggcactg taaccaagag
     3121 ataagggtaa aataccttca ccaattcctc cagcaaggac tggcgtcaca acataaaaga
     3181 gggtatgttg ccagtctaat cctaaaatga cgccaaccaa agtccctaca cccattgcac
     3241 aaaccattcc aagtaacatg ggaataatca tccgaaaaag accttgaatc aagatttttc
     3301 gattcatgcc taaaatacta ccgcagacca ggcaggcaat ataaaaataa agaaaattgg
     3361 cttgcttcat caagacattc gtcgcttcta agacattggg gttgaggaga ttaaaaaaaa
     3421 ccaaaatcga agggactaag agtgataaaa tagctgggcc accaaaatgt ttgaggcctg
     3481 gaatggtcgc tccaatggtt cctagtagcc aaccaagggt taaaataaca gcaaagccac
     3541 ccagcatatt aacaggcagc tgttggagcc agcctgtgac taaaattaag gtagctaaaa
     3601 ccaaataaac agtcaaggga acggagccta ttcgcctatt ttgccatgct tttgaatgct
     3661 cagacaagtc tttttgaggc attttcttgc ttattgtttc catgaaacaa cctcctttag
     3721 tgataaggct agtataaaag agaacatgtc aaaagcatag tttatttaag ctgtttaact
     3781 actttaattt tttcaagtta tttaattaat ttaaactagc aggtcatttc ttatcgtgtt
     3841 atactcaata aagaggagac cttatgaaaa aaccactacg tttatgggcc agtttatcgt
     3901 tgattttggt atctatgatt gttgtcacaa cctctctatt ttacgggatt atgctacatg
     3961 atacgcacca atccatcaaa aatcaggaaa cccatttgct aacgtcaact ggaaaaatgt
     4021 tagcaagtca tcaagcaatt aaagaattac tcctaaacaa ccaaccaaat gctaaaacaa
     4081 cagcctatac caactccatt gcctccatct ataaccttga ttatgtggtc gtgatgaaca
     4141 tgaaagggat tcgactcacc catcctaacc cgaaaaatat cggaaaacct tttcaaggag
     4201 gtgatgagga ggctgttcta gcaggaaaaa aggttatctc taccgccaag ggcactttag
     4261 gaaagtcact tcgctatcta gtacctgtgt ttgacggtga caaacagatt ggtgctattg
     4321 cggttggcat taaactaact accctaaatg atgtggcttt aacgtcaaaa cgcaattata
     4381 ccctgtcttt actcctttgt cttcttatta gtttactggt caccagtttt atttcttttc
     4441 gactcaagcg tcaactgcac cagttagaac caagtgaaat ttaccagctc tttgaagagc
     4501 gtaatgccat gttggatcaa atcgaagccg ccgtatttgt ggtagataaa gctggtatct
     4561 tacagctctg caatcaggct ggacaaaaat taattgctcg gaaatgccag ttgggaaaac
     4621 ctactggcaa cagtttcaat cacctctttc ctgattttcc aaaacttagt ttgcaagagg
     4681 ggcatgaaca actctttcgg tatggtgagg aagactactt gttagccatt tcacccatct
     4741 gtgtcaaaaa cgatcaccga ggccacatta ttttcatgcg agaagcagtt aaggctattg
     4801 ataccttgga tcagctagcc tataccaccg cctatgcttc tgctctacaa gcccaaactc
     4861 ataaattcat gaatcaattg catgttattt atggcttagt ggatattgct tattatgacc
     4921 aattgaaaat ttatttagac agtattttgg agcccgaaaa tgaaattctc actagcttat
     4981 ctgtccttgt taaggagcct cttctagcta gttttctcat tggagagcaa gagaaatacc
     5041 aagaattaaa tgtccatctc aagattgatg ttttaagcga gattcctcat tctgccacca
     5101 agaatcaact taataatggt ttgatgattt accgctttat ccatactaat cttctaacca
     5161 cactgagacc caaatcactc gttttgagta ttcaacatga tcagaatcat ttaatcagcc
     5221 attacacctt gacagacaat tggattgatt tggagcgggt acagcctatt tttgacttac
     5281 cttattttca acagctcttg accgatacaa attccaaatt ccatcaacat caaaccgtaa
     5341 ccgagttaca gttctcagtg acaacacctt atgtaggagg gcaacatgaa cgttttaatc
     5401 attgaagatg atcccatggt ggattttatc catcgcaatt acctcgaaaa actaaatctt
     5461 tttgatcgca ttatatccag cgactctatg aaagctgttc aaagcatact tactgattac
     5521 gcaattgacc tcattttact ggatattcat attacagatg gcaatgggat tcaatttttg
     5581 gagaaatggc gtgctcagca tattccttgc gaagtcatta ttatttcagc cgcaaatgat
     5641 gggaatatta tccgagatgg ttttcattta ggaattatcg actacctcat caagcccttt
     5701 acctttgaac gctttcaaga aagcatccaa cagtttgtta cacatcgaga acatttggcc
     5761 aatcagcaac tagagcaggc ccaaattgac caactgaaat gtttgactag caaaaaagac
     5821 actaaaaaca aacaattgtt agaaaaaggc ttatctgaat ccactttcca gtggattatg
     5881 gaaaatatca aagcctttga tcaacctttt actatccaag aattagcttc cgcttgtcac
     5941 ttatcccatg tctctgtccg taaatacatt gcttatttag aagaaaataa gcaactgaac
     6001 agccagcaaa tttttaccaa ggttggccgt ccctatcgcg tgtactggtg acgtcatctg
     6061 tcgatacatt aaaaaggctg gagaaatacc agcctttttg agtgcttatt tgcgatacat
     6121 tttaaattgg aggtataaat cattataaat ccccaaccat cttgacccta aattatcata
     6181 aacttccaat tttttgataa tgccatctgt tggataaaaa gcaggatcat tttttatctc
     6241 atctggaagt aaggccttgg cttttttatt tggtgtcgca taaccaatat atgcagcatt
     6301 ttgcgcagca ttttcaggac gattgataaa gttcaaaaaa gcatacgctt ctttttcatg
     6361 tttcatggtt tttggtagta ccaaattatc aaaccaaagg ttagaccctt ctgaaggcac
     6421 gatgtagtga aggtgttcgt tactatctaa catctcactg gcttcaccag aaaaggtaat
     6481 tccaatagca gcgtcacctt gaatcatgta gcctttcatc tcatctgcta caatggcttt
     6541 aacattcggc gtcaactgct gcagttttct ctcggctgcc tgcaactgct ctagattttt
     6601 agaattcaca ctataaccaa aagttgttaa accaacccct agcatttcac gcgctccatc
     6661 aatcagcata atactatttt tatattctgg acgccacaga tcttcccagt gcataggcgc
     6721 cttatcaact aattgatcat tataaacaat cccaacggtt ccccagaaat aaggcaaaga
     6781 atagtcgttt tgtgggtcaa agcttttccc taaaaattct ttcccgatat tatccatgcc
     6841 aactaatttt gacttatcaa gcttattgag taggttttct ttgatcattt tatcaatggt
     6901 gtaatcacta ggaacagcaa tgtcgtaagt ggttccgcct tgcttgattt tagtgtacat
     6961 ggcttcattg gaatcgaaag tttcatactg cacttcaatg cccgtttctt tggtgaattt
     7021 tttgagcaaa gctggatcaa tgtaatctcc ccagttataa ataactaatt tatccgattg
     7081 actaccagaa cctgattttt tctgcaagat gaaagaaaga cttgttaaaa taacaataac
     7141 acccaaaact cctgctagaa aggaataaag tttacgcatg tttttcctcc ttgtcctgtg
     7201 acatataata ataaccgatc actaagagga tggagaaaaa gaaaacgatg gttgacaaag
     7261 cattgatatc caaggaaatt ccctgacgag cccgcgaata aatctcaaca gataaagtag
     7321 taaaaccatt tccagtcaaa aagaaagtca ctgcaaaatc atctaaggaa taggtaaagg
     7381 ccataaaata acctgcaata atccctggtg ttaagtatgg cagcatgact tctttgagca
     7441 tttggaaata attagctccc aaatcataag cggcgttgac catgtcttga ttcatctctt
     7501 tcaagcgcgg caataccatc aaaaccacaa taggaatcga aaaagcaata tgacttaata
     7561 aaactgaaga catgcccagc tgaaacttca atgatgtaaa aagaattaaa aaggaagccc
     7621 caatcatgac atctggtgat accatcaaga cattattggc tgatagcatg gcattttggt
     7681 acttacctct aacatggtgg ataaagatag ctccaaaggt cccaataatc gttgctagta
     7741 gagcgctact aaaagcaaga acaaaggttt gcagtaagat tgtcatgaga cgactatcct
     7801 caaacatggt ttggtaatgc tcaagggtaa atcctgtaaa accattcata tccccacctt
     7861 tgttgaaaga atagaaaatc aaataaaaaa taggaatgta gagtaaaaca aagacactcg
     7921 ttaaataaag attggcaaat tttttcattt acttttctcc tttgtgagcc acataatagc
     7981 aatcatggtt aaaattaaca ccacacctat ggttgatccc attccccagt tttgggtggt
     8041 caaaaaatgt tgttcaatgg ctgtaccaag tgtaatcacc cggtttccac caatcaaacg
     8101 ggttaacata aagagactca aacttgggat aaagacagac tgaacacctg ccctaacccc
     8161 atttaaagaa aggggaaaaa taacttttga gaaggcctga aattcactag ctcctagatc
     8221 gcgactggca ttgatgacat tatggtcaat atcatccaaa gcattaaaaa tcggtaacat
     8281 cataaaagga agctcaatgt aagaggctac aaaaatgaag gagaaatccg tgaaaaggat
     8341 ttgctgcggg ccaatcccca taaaggttaa aaagctgtta atccctcctt gttgaccaaa
     8401 gattcccata aaggcatagg cttttagcaa taagtttacc caagttggca aaataatgag
     8461 cataagccac aactgcttgt gctttaggcg cgttaaaaag agagccgtag gatatgaaat
     8521 taagagcgtg acgagtgtga taataccagc gtataaaata gaattcacac tcattctcaa
     8581 ataggtccaa gagctaaaaa aggtttcata attggctaag gtcacgcgcc cttctatgtc
     8641 aaaaaaggac ttgtaaaaca agagagtgac tggtgccaca acaaagaaga gaatccataa
     8701 gaagtaagga atcgaaaaaa gactagaggt tttcttcatt acgctcctcc tcaatggcat
     8761 taatcaatcc atcttcaggc tcatccattt ccacatattc ttcaatacgg gcatcaaatt
     8821 cctcttcagt ctcattaaga cgcatgatat gaagatcttc aggggtaaaa tctaatccga
     8881 taacttctcc ttcgatagct ttgcgggtag aatgaatcat ccattcatta cccaattcat
     8941 cataggcaat aatttcgtag tgaaccccgc ggaataattg ggtatcaacc ttaacttgta
     9001 atttcccttc ttctggcaaa gtaatttgaa gatcttcagg acgaataacc acttcaacag
     9061 gctcattagg gcgcattcca ccgtccacag attcaaattc tttcccgtta aaggagacaa
     9121 gatagtcttc aatcatggta ccgttaataa tattagattc tccaataaaa ttagcaacaa
     9181 aatgattaat tggctcatcg taaatatcca ctggtgttcc cgactgaaca atttcacctt
     9241 cattcatgac aaaaatccaa tcactcatgg ccaaggcttc ttcttgatcg tgagtaacaa
     9301 aaacaaaggt aatacctaga cgttgttgca attcacgtaa ttcatattgc atctctgttc
     9361 ttaatttcaa atcaagggct gagagtggtt cgtcaagtaa gaccacacgc ggttgattga
     9421 taatcgcacg cgcaatggca acacgttgac gttgaccacc agataacttc tggatagaac
     9481 gattttcata cccttctaat tgaaccattt tcaaggtttc tttcacgcgc ttagcaatct
     9541 ctttcttgtc cactttcttc agcttcaaag caaaggcaac attctcaaaa acagtcatat
     9601 gagggaagag ggcataattt tggaaaacgg tatgaatgtc acgtttatta atcggcaaat
     9661 cattaatacg ttccccatct aaataaatgt ctccgctgct ggcatctagt aggcccgcca
     9721 taatatttaa aatagttgat tttccagagc cagaagctcc aagcagggtg taaaattttc
     9781 cttcttcaag gtcaaagtta atgttcttta gaacctgtgt tccactgtcc tcaaatgttt
     9841 ttgaaacatt gttaaatgtg ataattggct tagtcaattg tcataaatcc tccacggtac
     9901 tttctttaat tatcaataat ggttacaggt tttccccaat aatccgaact tctggttcaa
     9961 gcctgacacc agaatggttt tcaactgtct caatgacata agcaatcaaa tcttcataat
    10021 ctttagctgt gccatctgcc acattaatca taaaaccagc gtgtttttcg gaaacttcca
    10081 caccaccaat ccgatgccct ttaagatttg cttccatgat taattgacct gcaaagtgtc
    10141 ctggcgggcg cttaaacaca gatccacaag atggaaattc taaaggttgt tttagttggc
    10201 gaaggtgatt taaccgattc atttcttggc tgatcgtatc ataattaccc ggtttaagag
    10261 caaacttagc agaaatgaca atgtcacctg tttcttgaat ggcagagtga cggtaaccaa
    10321 aagccatatc cctagctgaa atggttttga tctctccact tgaggtaagc accttagcgg
    10381 ataagaaaat atgtgatatt tccccaccat aggcacctgc attcataaaa acagcacccc
    10441 caatgcttcc aggaatgcca catgcaaatt caaaccctgt taaactatgg aatttggcaa
    10501 tcttcgttgt ttcaatcaga ttggcaccag cttcggcttc taaggtataa ccatttaagt
    10561 gcactgcatt tagcttatca aacatgatga caaagccacg aataccacca tctcgcacaa
    10621 tgagattgct ggcatttccc aaaacaagcc aaggcatatt ttctttgttg gcataagcaa
    10681 cgatgcgtga tagctcgtag tgatttctag gaaaagccaa gaaatctgct gggccaccta
    10741 ccttagtgta agtgtaatgt tttaggggtt cattctctcg aatatcaatc ccatgaagtt
    10801 cagttatcat agttatcttc tttcttttat cacttcttat acgcgtaaaa aaatcggcat
    10861 aaagccgata ctattatatc aaattttaga aaaaataacg atgaatttgg caaaacttta
    10921 tggattggct tatagcaggc attactccga aaacagagtc tagaactctg tctgttgagc
    10981 tgaaaagagc gtgatatctg attgatctaa agctgcaaga taatccctta aaaacttatg
    11041 attaggaggc aattttaaat ctggctgcaa ttccaataag gggattaaaa caaaagcacg
    11101 ctcagtcata taagggtgtg gcactttcaa ttcctttgtg tcataaacct cttctccaaa
    11161 tagcaagata tcaatgtcaa tagttcttga tccccatttt tcatgcctca cacgaccaag
    11221 agattgctca atagcttgtg tttcttttaa gaaatcagcc gcggttaatt gtgtatctaa
    11281 ttgacaggcc atattgagaa aatcagcctg gcctgtcttg ccccaagcag tcgtttcata
    11341 aatggatgat tgagcaagca accgtgtttg aggtaagtca gctaaagcct caagagcttt
    11401 ttgcaagtaa gctgctcggt cccccatatt ggtgcctaaa cttaaataaa caatggtcat
    11461 ctctgtctct ccaattcaat accaactgcc ttatagtggc ctgcaatcgg tgggttttcc
    11521 tttttaatgg ccactttgat ggcttcaata ggtggaaatt cgttaaaaag ctgttcacaa
    11581 atcgcacctg ctaaacgttc aatcaaaata aactttcccc cttccactaa ctgacggaca
    11641 ctatcaaaca ccatcccgta atggaccgta tctgttaatt ggtctgacaa agaagctgct
    11701 tgcaaatcga ctgacaattc taaatcaacc agaaaaattt gcccaagggt ctgttcttct
    11761 ttaaaggctc catggtagcc ataaaaacgg caaccttcta atacgatttt atccataagt
    11821 cctcacatca actagctcaa aacagccaca atgtcttgat tagccttgac atcgtgtacg
    11881 cgtacaatct gacagccttt tccaagggca taagcagaca aggctgctgt cgctccgtct
    11941 cgctctttag ctttggtgtt gccgcctaac aaggcatcta cgacacgctt tctcgaaata
    12001 ccaaacaaga caggatagcc caactgacag acgcggtcca atccttttaa taactccata
    12061 ttctgttgaa cagatttggc aaatccaaat cctggatcaa tccaaatatt gttttttggc
    12121 acgccagcat caagagctgc ttgtgctcta ttgcctagaa aatcacaaac gtcttgtgtt
    12181 acctcttgat aaacttcttc gtcttggtta tgcatcaaga tgataggcgc atcgtactcg
    12241 gctgctaagg caaacatttg tccgtcgtac aaacctgccc aaacatcatt gagaatatcg
    12301 gcacccgcct ctaaagctgc tctagctgtt tcggttttat aggtatcaat gctgattaga
    12361 atatcatagt tttctttgat ggccttgatc acaggaacca cccggtcaat ttcatcggta
    12421 gcgcttacaa aacggcaacc tggacgtgtt gattctccac caacgtcgat gattttagca
    12481 ccatcagcaa tcatttgctc aacgtgatct aatgcttttt gcacagtagt gtaagacccc
    12541 ccatctgaaa aagaatctgg agtcacattt aaaatcccca tgatagccgc attgccctca
    12601 atcacaaacc ttccaatttt cataagtcct cctaatcttt tgtcattaga gaaataactt
    12661 cttgtctctc agcacgactt tccttgtata agcctctggc agtggtggta atggttttac
    12721 tacctggctt tttgatgcct cgcatggtca tgcacatgtg ctctgcttct accataacta
    12781 aagtcccttt aggattgagg gcttcaacta aagcatccgc tatttgagag gtcaaacgct
    12841 cttggagttg aggtcgttta ctagctactt caactgctcg cgctaattta ctcaaacctg
    12901 ttactcgacc atcacttggt aagtaagcga tatgagcctt gccataaaaa ggaactaagt
    12961 ggtgttcaca tatagaataa aaactaatgt ctttgacaat caccacatcc tcatgttgtt
    13021 ctttaaagac agccgtaaac tcctctttag gatcttttcc cagtcccaaa aacatctccg
    13081 catacatttt agcaacccgt ttaggcgtgt caagaagacc ttcccgattt ggattttcac
    13141 caatagcctc taaaaactga taaatggctg cttctgcttt ttccttatta atagacatta
    13201 gtctttccct tttcattagt tttttccttt tccttttcat tttctctttt ttaatgggtt
    13261 aaaagaacgt ttttttcaat atgttttttc caataccgtc taatttctga aataaaatat
    13321 agtgaccctg taatcacgaa aaagtcatct gctttagcat gcttacgcag ggccaagaaa
    13381 tctttgaaat cagcaaccct accaaaacgt tctgggtatt tttccaatgg ataggcgtta
    13441 gggtaatgaa agccagtaac ctgcaagtca cctatttgct caagagcaac caacatatcc
    13501 gcaataggct tggtgtcgat cgcaccaaac aaaatatgaa gctttttatc attgtagtta
    13561 ttttttaaga cggctaccaa agcagcaacg ctttcattgt tatgagcccc atcaatcatt
    13621 agatttggtg ctaataattc ggtacggcct agccacaaac tatttgccag accttccctt
    13681 atatgatctg aagttagcct aggatagcgg tctttcaagg ttaagcaagt cataatagct
    13741 aaagctgcat tagacacttg gtggtgtcct ggcatagcga tgtgaatatc tgaaataact
    13801 cctaaaggac tagtaaaacg atagccagat gcgttctcag ccatttgaaa ctgctcttgc
    13861 cattcccaga ttgaagcacc aacctgctca gcttttgtta aaaaaacctc tcgagctgac
    13921 gggttttcaa cggcaaaaac aagggtctcg cccccttcta aaacaccagc tttttgggcg
    13981 gcaatatcag cgtaagtctc tcccaaaata gcttggtgat ctaaaccaat tgagggacat
    14041 accacaacca ttgcttgaaa aacattggtc gaatcataaa gaccgccaag gcctgcttca
    14101 ataatagcaa tatctacagg atgcatgtct ccaaaataga ggaacatgat caaagtaatc
    14161 acttcaaatt cagttacctc tccaaaatca gtctcttgaa ctagacgctc tgtcaaagga
    14221 cgaatacgat tagcagcaat aaccaaatct ttttctgaaa tcattcgacc atttatgcta
    14281 atacgttctt tgaaatccat aatataagga gaggtaaagg tccccacttc ataaccagct
    14341 gtcgtaaaaa tgtgttgtaa atgattgacc gtggaacctt ttccgttagt tccaacgata
    14401 tgcactccct tgacattttt ttggggattt cctaactgtc caagaaccca aagcatacgt
    14461 tttaagcctg gcttgatgcc gaaaactaag tgatcatgaa tccattctag agtctcttca
    14521 taagtcattt cacacctcac atctatcttt agtataccat atataaaaaa aagtgacagc
    14581 agataaccta gagtagtacc ctttttttat tatcctcacc aaacactcaa ataagttcta
    14641 aagtacacta cacttttatc ttcattgctt tttttacgtg ataagaatac cagccccaca
    14701 tagtctttgc tacctcctaa agtgttatct gtgacaataa tttttttact ccttaataca
    14761 cgttcttcca aaaaacaaga aaaaaggctg acttcaagcc ttcttttctc taaaaaatgt
    14821 tacaatagag gtacttatat caaaaaaagg agcaagtaat gaacaataga cataaacggc
    14881 gccaaaaaag aaaagccttc actctcatta accttatact attatttgcc tgcattcttg
    14941 gtttgaccct cattttctat ttataccaag ggtctaacaa attcggcttg tcagatgtct
    15001 ctcaatttgt acctaaaata agtctttttc atcacaaaaa gacggcaaaa aaagaaacga
    15061 caaaacttaa gaagactcat ttcgattcct caaaatctca aaaaaaggcc cattctaaat
    15121 taacttggac caagcaagaa acacctgtca agatccccat tttaatgtat catgctattc
    15181 atgtaatgtc ccctgaagag acggccaatg ctaatttgat tgtcaaccca gatctctttg
    15241 atcaacaact tcaaaaaatg aaagacgagg gctactattt tttgagtcct gaagaggtct
    15301 accgcgctct ttcaaataat gaattgcctg ctaaaaaagt tgtatggcta acatttgatg
    15361 acagtatgat tgatttctac aacgttgctt acccaatctt aaaaaaatat gatgctaaag
    15421 ccaccaataa tgttattaca ggactaaccg aaatgggaag cgctgccaat ctgactctta
    15481 agcagatgaa agaaatgaaa caattcggta tgtctttcca agatcataca gtgaatcatc
    15541 ctgatctaga gcaggctagt cctgatgttc aaacaactga aatgaaagat tcaaaggact
    15601 atcttgataa gcaattaaac caaaacacta ttgccattgc ttatccatct ggtagatata
    15661 atgacactac cttacaaatt gcagctagac ttaactataa attaggtgtt accactaacg
    15721 aaggaatagc tagcgcggct aatgggcttc tttctcttaa caggattcgt atcctcccaa
    15781 acatgagtcc ggaaaatctt ttacaaacaa tggaaccata acatcaattt ttttatcatt
    15841 ccaaatcata ctcactgtaa actaaaaaga cagttatgaa aaaattcttt cataactgtc
    15901 tttttttgat tgttttaaaa ttattttatt cttatcttta acgtcttttt tcaagaaaat
    15961 ctcgccacca cagctgtaag tcagaggctt ttttaagaga ttggctagct ttaagaggaa
    16021 tacgcttagg ttcctttaaa tacctcactg actgatctgt tattcttgga gacgtcaaat
    16081 aagcaaccac ttcaccttta gtaatcggtg ctagtaaaga agtctctgat atcataaatt
    16141 gtttaggttt gggaacttgt tcaccctgtt gcaaaatgat ggttacatct tcggcaacag
    16201 ataccggtag ttcttttact tggccatctt gaatagggag cgaccgctcc gagacaagac
    16261 ttcctttttt aagaatctta cgacgacaat aagttctagc cacatagtcc aacaaacgat
    16321 ttgcttgctc aaaccgcgtg ttttggtttt tatcagatcc atcggcattt agaataacgg
    16381 taatcactcg cataccattt tcaatagaag ttaccacaag acaatgacct gccaagtctg
    16441 ttgtcccagt ctttaaacca tccactcctg ctctaccctt agccatacct ggtaagagtt
    16501 gattaaaact tttaatagaa ttgccagcaa aattaacttc tgtttgtttg gtgatctcta
    16561 aaatctcagg aaaatcttct aacaaatgca tcgtcacaac tgcaacatct tgagcactca
    16621 aggtattttc ttcttccaac gcagaaccag gataacgatt atcctttaac acctcatttg
    16681 gcagacctga ggcgttgagg attttaccag aagtaatccc ccaatgagat agctgttctc
    16741 tcatttgatt tacaaaatga agctctgaac ccgccacttt ttcggctaac gcaatagcag
    16801 cgctatttga gcttgctacc aaagtagctg tcaacaggtc ttgaactgaa taagtttttt
    16861 tgtcaaaagg tacattactt aaagacctat cttttgttaa ctcaaaggca taatctgaga
    16921 gattaacttg atctgataat tgcagctggc ctgatttaac cttatctaaa accagataag
    16981 ccgtcaccaa tttggtcaaa gaggcaatag catctggcgt cttagcgtct ttctcataca
    17041 gaactctccc agagtctgcc tctacgacaa tcgcatgttc tgctcccact tgaaaatcag
    17101 ctgcgagaac tgttttacca aaccctgaac aagttaatac cataaaaaaa aggataaccc
    17161 acctttttat cattatatct ttcatagtta ctattataac aaaaattctc agaaatttgg
    17221 aaggaagtat agtggcacac acctttagta gcttaaacaa gctcataaag caagtaccct
    17281 gtgacaataa cacatcctgt tatatgggcg atataataag cttcgttata tcaattagtt
    17341 gtttggcagg aattttggta taaaatggaa tctaatcctg aacttattac attttgggtt
    17401 atttcttcag atactgtttt atctaatgca ttaaaccagt gactatatgt attcaaagtt
    17461 gtagacttat cagcatgtcc catacacttt gcaacgtaca gaatgtcttt tttcaaaaca
    17521 ttaataagat aggaagcatg actatgtcgc aagacttttc ccgttatcac tggtactcct
    17581 acttcttgag ctttgtgctt aataactcga caaatcgttg atttacaaaa tggttcacca
    17641 aaccgtgaaa taatgaaatc tgtgtcagta ttgactactt gatttcttct ccaattttcc
    17701 aatactacta ttgtcacatc atctaactca ataagacgtt ctcctgctgg cgtttttgtt
    17761 tgatctttac gataccaatt tccattttca tccttttcca aggttgtatg aactttcaaa
    17821 aatttttgtt cgaaatcgat atcttcccat cataatgata aaccttcact tacacgaaca
    17881 cctgtcatat aatatagcca aatagttgta aatctttgta gctcttcata atcttgcaaa
    17941 tcaaacgatt ttataaaatt ctgaaactca atataagtcc aaaatggagt atcgggatgt
    18001 ttccctttag gattatccaa agccttacac ggcacttttg aaatatagtc taacctttca
    18061 gcatacccca tgcaagcttt gaatcgcgac cataaattct ttgcataatt ttcaataata
    18121 tgtaaactaa aagattcaca atctcaagct gttattccct ttaaaagttt agaaccaaaa
    18181 tactgaataa ataact
//
LOCUS       DAUCXI010000036        18086 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.036, whole genome shotgun sequence.
ACCESSION   DAUCXI010000036 DAUCXI010000000
VERSION     DAUCXI010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18086
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.036"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            180..1739
                     /locus_tag="VGY43_001351"
     CDS             180..1739
                     /locus_tag="VGY43_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEQ4302529.1"
                     /translation="MIELNDEFIRKETIELANDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSDAFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTGFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPFTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMENVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGVGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKASHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLSTNYKVDKQI
                     TTKSFIVYQKK"
     gene            1836..4034
                     /gene="nrdD"
                     /locus_tag="VGY43_001352"
     CDS             1836..4034
                     /gene="nrdD"
                     /locus_tag="VGY43_001352"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEQ4302530.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            4216..4362
                     /locus_tag="VGY43_001353"
     CDS             4216..4362
                     /locus_tag="VGY43_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302531.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSKKKTDKKSRVQELKARFLEKSK
                     KQDN"
     gene            4391..5326
                     /locus_tag="VGY43_001354"
     CDS             4391..5326
                     /locus_tag="VGY43_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEQ4302532.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKTNLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENQTFLMAGFNRRFTPRVKKLSSLSTKRKVAVEKNDLNRPGDMTFKLFDF
                     FIHPLDTALFLTEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTEKRVLSFASWDTTLHKRGFETMINAFLEAISTGV
                     NPVSPESSLLSHWICQQIADSQLSYGELTVELPKD"
     gene            5335..5844
                     /locus_tag="VGY43_001355"
     CDS             5335..5844
                     /locus_tag="VGY43_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ4302533.1"
                     /translation="MEIRRPTLKDKDAVLSMINEFLEQKSATDGLWHFNVNDFNYETW
                     LEDSLRQEMGLSSQGVPAIQYVAFDERSQAIGFLNLRLRLNERLLEKGGHIGYSVRPS
                     RRGKGYAKEMLKQAVSYAISKNITTILVTCDETNVASRAVIVANGGILEDSRGGTERY
                     WIEEQRGDK"
     gene            5844..6458
                     /gene="nrdG"
                     /locus_tag="VGY43_001356"
     CDS             5844..6458
                     /gene="nrdG"
                     /locus_tag="VGY43_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEQ4302534.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRRELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(6632..7363)
                     /gene="yaaA"
                     /locus_tag="VGY43_001357"
     CDS             complement(6632..7363)
                     /gene="yaaA"
                     /locus_tag="VGY43_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEQ4302535.1"
                     /translation="MLTFLIPTAKEMMIPKESHPHLLPQDSQAILKIMAAMTTEDLAK
                     SYRIKEEAAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHPDLSTDHEFVYIKKEA"
     gene            complement(7405..8262)
                     /locus_tag="VGY43_001358"
     CDS             complement(7405..8262)
                     /locus_tag="VGY43_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEQ4302536.1"
                     /translation="MTSPYNSTISLGTVSLNVTDLAKMTTFYTSIISLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPANKAYGLYHTAFLVPDRHSLGLVLNHFLTRGISLEGSAD
                     HGYSEAIYLSGPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSILEQLTDIPKR
                     FLLAQDTRIGHVHLSVKNALASSLLYQKVFDLGDKMTIPSASWIASGNYHHHLAFNHW
                     SAPYLKKHQEGAPGLAFLTIHIETPLLFSATLKKARLHGLAILQEDSSSFTTEDEEGI
                     CVNVILGQD"
     gene            8449..8786
                     /locus_tag="VGY43_001359"
                     /pseudo
     CDS             8449..8786
                     /locus_tag="VGY43_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018307.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(9065..9778)
                     /gene="treR"
                     /locus_tag="VGY43_001360"
     CDS             complement(9065..9778)
                     /gene="treR"
                     /locus_tag="VGY43_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEQ4302537.1"
                     /translation="MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            9989..12013
                     /gene="treP"
                     /locus_tag="VGY43_001361"
     CDS             9989..12013
                     /gene="treP"
                     /locus_tag="VGY43_001361"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEQ4302538.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSGIEGVSKEAAKSAAKSNQNAL
                     QRVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLETFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANSIG
                     VGGLPGFMAINVKYMIPFFICMAVAIVVPMFLTFFFRKSHIMTKTEDEAKLPETPVSE
                     APAATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDAFTVTVEGSLPRQIKANDKLAVAMKK"
     gene            12081..13709
                     /gene="treC"
                     /locus_tag="VGY43_001362"
     CDS             12081..13709
                     /gene="treC"
                     /locus_tag="VGY43_001362"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEQ4302539.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYTAVNPDFGTMADFEDLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAE
                     EAFAIIKDKSRDNARTPMQWDASEHAGFTTGKPWLEVSKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQSVYAFERHLGDQCLLVLNHFYADEVELELPPR
                     YQHGQVLISNYEKVSICEKVILKPYQTLAILAEN"
     gene            13917..15812
                     /gene="pepO"
                     /locus_tag="VGY43_001363"
     CDS             13917..15812
                     /gene="pepO"
                     /locus_tag="VGY43_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEQ4302540.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGENIPDDAILKNFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTDDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDESLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEAAQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(15979..17019)
                     /locus_tag="VGY43_001364"
     CDS             complement(15979..17019)
                     /locus_tag="VGY43_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEQ4302541.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(17153..17920)
                     /gene="rpsB"
                     /locus_tag="VGY43_001365"
     CDS             complement(17153..17920)
                     /gene="rpsB"
                     /locus_tag="VGY43_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEQ4302542.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEKGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADTQADSIEEIVEVVEGDNA"
BASE COUNT         5270 a         3145 c         3988 g         5683 t
ORIGIN      
        1 taatatcatt tttcaactta ctttgtttat gcactgtcac tttgctatgt gcaatacaaa
       61 gtcatgttat ttatctcata ctaaaaaata atggataata gctatgttag actagtgata
      121 tgaagaaata ttgcttttat tgaatcgtta gagaatatga tatttcaagg agaaaaatag
      181 tgatcgagtt aaacgatgaa ttcatccgaa aagagacgat agaactggcc aacgatggcc
      241 cacgagtaca caccactcaa tatgaaacta aagtacctcg gcttcataaa tgctatctgc
      301 ttttctttag cattattatc agttctttaa caattgcagt acctttttta acagatgcag
      361 ccaatggtct tcagtcccaa aacttatata taggaatgat gttaacgaag gggcaacttc
      421 cctatagtga tgcttttaca acaggagggc tcttttactt tgttatcatt gcattaagtt
      481 attatttggg atcgacactt tggctagtct ttgttcaggt gttttgtttt tacttatctg
      541 gtttatatct ttataaactc attaattata tgacaggctt tcaaaaagtg gctttaactt
      601 tttcaattag ctactatttg ttgtctgtta gtcttggttt tgggggattg tatcctactc
      661 aactggctat gccatttata ttaatatcgg cttggttttt aactaagtat tttgcctgtt
      721 tagtgaaaga tgaggcattt attctttttg gctttgtagg tgctcttgca atgctaattg
      781 acccgagtac ccttatcttt tggtcttttg cttgtgtgac agttttttct tataatataa
      841 gccaaaagca tcttgcaaga ggtttttatc aactgctagc ttcgattttt gggatgattt
      901 tagtttttta cacagcagga tatttcattt tgaacttaca agtgctaaat ccttatttat
      961 cacaaacgat gatttatcct tttacttttt ttaaatcagg aaacttatcg ttgctttttg
     1021 gactggctat tcagttgttc ttcgctttgg ggcttggtct tttgacggga atggagaatg
     1081 tcattaggcg atttaaaaac aattctgata gggtcgtcaa gtggctattt gttatggtca
     1141 ttctagaatc tatacttgtg gctatatttt cacaagacta tcgcccctat catcttttac
     1201 ctcttttacc ttttggatta attttgactg ctattcctgt tggctatcag tatggtatag
     1261 gattaggtca gagtagtcat cgcagacgtc atggtaaaaa tggtgttggt cgagtaatga
     1321 tgatttatct taagagacac ttttatttgc caattttaat tgtagggaca atactaatct
     1381 gttctactta ttgtttcatt agtagtattc ctcttaatca ggagcgtgat catattgcta
     1441 gttatttaga acagaaacta aataaaactc aatctattta tgtttgggat gatacttcta
     1501 aaatttattt ggacagtaaa gctaaatctg tttctcaatt tagttctcct gacatcaata
     1561 cgcaaaaagc gagtcatcga aaaatattag aagatgaact attagaaaat aaggctgctt
     1621 atatcgttgt taatcgctat aaaaacctgc ctaaaatcat tcaaaaagta ttatctacta
     1681 attacaaagt agataaacag ataacgacaa aaagttttat tgtttatcag aaaaagtaat
     1741 ctaatatcaa tatattgtgt tcgagcaaaa aacttgacac aatatattga tttttttagt
     1801 tgtcgtgata taatagttcc gtaaggagat ttgatatggt aagtttagaa gaagacaagg
     1861 tgactgttca acctgatatt aaagtgatta aacgagatgg tcgccttgtt aattttgata
     1921 gtacaaaaat ctatagtgct ttattaaaag caagcatgaa agtaactcgg atgtcgccac
     1981 ttgttgaggc taaattagag gctatttctg atcgcattat agcagaaatt attgagcgtt
     2041 ttccaactaa tatcaaaatt tatgaaatcc aaaatattgt agagcataag cttcttgcag
     2101 ctaatgaata tgctattgca aaagaataca ttaattatcg tactcagcgt gactttgcac
     2161 gttcacaagc aacagatatc aatttttcta ttgataaatt aattaataaa gatcaaacag
     2221 ttgttaatga aaatgctaac aaagatagcg atgtttttaa tactcaacga gatttaactg
     2281 ctggaatcgt agggaaatcg attggtttaa aaatgttacc ttcgcatgtt gctaatgctc
     2341 atcaaaaagg agatatccat taccatgatt tggattacag tccttataca ccgatgacga
     2401 actgctgttt aattgacttt aagggcatgt tagccaatgg ctttaaaatt ggtaatgctg
     2461 aagtggaaag tcccaagtct attcaaactg caacagctca gatttcacag attattgcga
     2521 atgtagcatc aagtcagtac ggcggatgca cagctgatcg cattgacgag tttttagccc
     2581 catatgcgga gcttaacttt aaaaaacata tggctgatgc taagaaatgg atcgttgaga
     2641 ctaagagaga aagctatgct tttgaaaaga ctcaaaaaga tatttatgat gcgatgcagt
     2701 ctttggagta tgaaattaat acgctcttta cgtctaatgg tcaaacacca tttacttctt
     2761 taggatttgg tttggggacg tcttggtttg aacgtgagat tcaaaaagct attttgacca
     2821 ttcggattaa tggtcttggt agtgaacatc gcacggctat tttccctaaa ttaattttca
     2881 cggttaaacg tggcttgaat ttagaaccag attcaccaaa ctatgatatt aagactttgg
     2941 ctttagaatg tgcgactaag cggatgtacc cggatatgtt atcttatgat aaaattattg
     3001 atttgacagg atctttcaaa tctccaatgg gatgccgctc tttccttcaa ggctggaaag
     3061 atgaaaatgg gcaagatgtg acctcaggcc gtatgaatct tggggttgtc accctcaatt
     3121 tacctcgcat tgccatggaa tcaaatggcg atatggataa gttttgggag ctgtttaatg
     3181 agaggatgct aattagtaag gatgctttaa tttatcgtgt cgaacgtgtc acagaagcaa
     3241 aaccagcaaa tgcccctatt ctttatcaat atggtgcttt tggaaagcgt ttggagaaga
     3301 cagggaatgt aaatgatctc tttaagaatc gtcgtgcaac agtctctctt ggctatattg
     3361 gtctttatga agtggcgtct gttttttatg gtggtcaatg ggaaggtaat ccagatgcta
     3421 aagcttttac cttgtcaatt gtcaaggcaa tgaaacaggc ctgtgaggat tggtcagatg
     3481 aatatggtta tcatttctct gtttattcga ctccatcaga aagtttgaca gatcgctttt
     3541 gtcgtttaga tacggaaaaa tttggcattg tgacagatat tacggataaa gaatactata
     3601 caaattcttt tcactatgat gtgcgtaaga gtccgacacc ttttgaaaaa ttagattttg
     3661 aaaaagatta tccagaagca ggtgcttcag gtggttttat ccactactgt gagtatcctg
     3721 ttttgcaaca aaatccaaag gccttggaag cggtttggga ctatgcttat gatcgtgtgg
     3781 ggtatttggg aaccaatacg cctattgata aatgctataa ttgccaattt gaaggtgatt
     3841 ttaccccaac agaacgtggt tttacttgcc caaactgtgg caataatgac cctaaaacag
     3901 ttgatgtggt caaacgtaca tgtggttact tggggaatcc tcaggcccgc ccaatggtta
     3961 acggtcgcca taaggaaatc tctgcgcgtg taaaacatat gaatggttct actataaaat
     4021 acccaggcct gtaaactcaa gctgggggag agcccttttg atggaaatat gatatgctta
     4081 aaaggttgct tcatgcaagc aatcttttat tgtttaatgg tttcttagca attgtgagat
     4141 aagaataact aatccaaaac gactaattag ctgttagcaa tcggactata agaagaaaga
     4201 gataaggaag aaataatggg aaaatatcaa ttagactata aaggaatgca gcaggtagaa
     4261 cgctttcatg agaagcattc taaaaaaaag acggataaaa aatcccgcgt tcaagaactt
     4321 aaggctcggt ttttagagaa gtcaaaaaaa caggataact aaagtatcca ataaagaaag
     4381 aaggttgagt atgcttaata ttggtattgt gggactaggt gccatttcac aaaaagccta
     4441 tttaccatat atgagacagc tgagtgacat tacttggcat ctatcaacgc ggaatgcagc
     4501 agtacgtcag caggtcggtc agttatttgg tcacgctatt ctttacagtg atgtcaagga
     4561 gttgtcaaaa acaaacttag atggggtctt tattcatgcg gccacatcgg cccacgcaga
     4621 gttggctagt ttatttttaa atcaggggat cccagtcttt atggataaac ctatagctga
     4681 caattacctg atgacaaaga acctttatga cttagccaaa gaaaatcaga cttttctgat
     4741 ggcaggattt aacaggcgtt ttacacctcg tgtcaagaag ttgtcaagtt tgtcaactaa
     4801 gcgtaaagtg gctgttgaaa agaatgactt gaaccggcca ggagatatga cttttaagct
     4861 ctttgatttc tttatccatc ctttagatac agccttattc ttgacagaag ggaccttact
     4921 aaaagggcat tttcaatatc atctggaagc aggcttactg agtcaagtta tggtaacctt
     4981 gatgaccgaa agcatgacga ctacagcttc tatgaattta caatcaggga gtcgccgtga
     5041 ggtaatggaa gttcaacggg ctgaagaaac ttatcattta gagaacttag acgagttatc
     5101 tatttataaa ggtactgaaa aaagggtgct tagctttgct tcttgggaca ctaccttgca
     5161 caaaagaggt tttgaaacaa tgatcaatgc ctttttagaa gctattagca caggcgtcaa
     5221 tcctgtcagc cctgagtcta gtcttttaag ccactggatt tgtcaacaga ttgctgactc
     5281 tcagctttct tatggagagt taacggtaga gttgcctaag gattaggaat tgatatggaa
     5341 ataagacgac cgactttaaa agataaagac gctgtattgt caatgattaa cgaattttta
     5401 gagcaaaaaa gtgctacaga tgggttatgg cattttaacg tcaatgactt taactatgaa
     5461 acatggttgg aagattcctt gcgacaggaa atgggtttgt ccagtcaagg agtgcctgct
     5521 attcaatacg tcgcatttga tgagagaagt caggctatcg ggttcttaaa tcttcgttta
     5581 cggttaaatg agagattact tgaaaaaggt gggcatattg gttactctgt ccgtcccagc
     5641 cggcgtggga aaggttatgc caaggagatg cttaaacaag ctgtcagcta tgcgatttcc
     5701 aagaatatca cgacaatttt ggtaacttgt gatgagacta atgttgcaag ccgagcagtt
     5761 attgtggcta acggcggtat cttggaagat agtcgaggtg gaacggaacg ttattggatt
     5821 gaagaacaaa gaggcgataa gtgatggcag aaaagtgttg gaataatcct aagccaaagg
     5881 aatggcaggc agaggagtta agtcaaggcc ggattattga ctataaggct tttaactttg
     5941 ttgatggtga aggggttcgt aattcccttt atgtgtctgg ttgtttattc cattgcaagg
     6001 ggtgttataa tgctgcgact tggtctttta aggcgggaat gccttatacg caagaacttg
     6061 aagagcagat aatgacggat ttggcacagc cttatgttca gggactgaca cttttaggtg
     6121 gagaaccctt tttgaatacg ggtatcttaa ttcctctgat taagcgtatt cggcgtgaat
     6181 tgccagaaaa agatatttgg tcttggacgg gttatacttg ggaagaaatg atgcttgaaa
     6241 caccagacaa actggaaatg ttgtccttaa ttgatattct ggtagatggt cgttttgata
     6301 tcacaaaaaa gaacctcatg ttgcaattta gaggctcttc taaccagcga attatcgatg
     6361 ttcaaaagtc tttggctgct aaagaagtga ttatctggga taagttaaac gatggggacc
     6421 aaacctttga acaaattagt cgggaggatt tgctttaaga agctgactta tccacatgat
     6481 ttttttgaaa aggtcatgtg aaaacaggtc ctttaagggt gaattgggga gaaagtaatt
     6541 gttatttcct ggttttcccc acattatcct catagttatc cacaggttgt gtataagttg
     6601 tagaattgtg aataaagact aaaaaagagg cctaggcctc ttttttgata tagacaaatt
     6661 catgatctgt tgataggtct ggatggtagt aaaaaccagc aaagacaagg cttttaaggc
     6721 tgtcaacagt ttggcaatta ttttccatac aggcagtgag aaatgcacct cgtgcctttt
     6781 ttgaaatggt ggaatgggtt ttgaattggc cctctttttc tgccataaac ttgggactta
     6841 tccacaattg tttacagtct ttggaaaaga catcgtcaaa ttcactggat aaaagggaaa
     6901 tcacttgggg atgctctttg gcaaactgat tataacaggg ccgccagtaa gacttgaggc
     6961 tttgtccttc aatttttatt ctggtgtgaa aatcatggcg gtgctctgcg ataggatgat
     7021 tagcgggaat gataccgtaa aaggatgagg tgatgtaaac ttgctgggtg aggtaagcct
     7081 gttcttgggt agtgagctta tcgcgcttga tatggcggta cataaggcca ttgaacagtt
     7141 ggtaggcagg gtaagccaag ctttgttgag aggccatgtc ttgccagcgt tgctgttctt
     7201 ttttagctgc ctcttctttg atacgatagg atttggccaa gtcctccgtg gtcatagctg
     7261 ccatgatttt taaaatggct tggctgtctt gtggaaggag gtgtgggtga gattccttag
     7321 ggatcatcat ttcttttgcg gttggaatta aaaaggttag catagtgtta ttgtagtaaa
     7381 gttacttgct ttctgtcaag aaaactagtc ttgtccaagg atgacgttca cacagatacc
     7441 ttcctcgtct tctgtcgtga aagaagaaga atcttcttgt aaaatagcta ggccgtgtaa
     7501 tcttgctttt ttcagagtag ctgaaaaaag caggggcgtc tcaatgtgaa tggtcaagaa
     7561 ggctaagcct ggggcacctt cttggtgttt tttgaggtaa ggggctgacc agtgattgaa
     7621 tgcaaggtga tgatggtagt tccctgaagc aatccagcta gcacttggaa tggtcatttt
     7681 atcgcctaaa tcaaaaacct tttgatagag aagtgaagaa gccagagcat ttttgacact
     7741 cagatggaca tggccaatgc gtgtgtcttg agctagtaaa aagcgcttgg ggatatctgt
     7801 caactgctcc aatatgcttt tggtatccgt gggctcagtc acaccaataa tttgaccatt
     7861 gtcgcggata tcccaatgct caacagcttt gtcatgataa atttcaatcc cattgccctc
     7921 aggaccgctg aggtagatag cttcgctata gccgtgatca gctgatcctt ctaaagagat
     7981 acctctggtt aagaaatgat tgagaacaag tcccaagcta tgacgatcag gaactaaaaa
     8041 ggctgtgtga taaagaccat aagccttatt tgctggtaaa ggtgtttgtc gtaactctaa
     8101 gataacggtt ttaccgtctg tagtcaattg acgagatgtc gtgtcttgtg agagaacctg
     8161 taaactgata atacttgtgt aaaaggttgt catctttgct agatcggtaa catttagaga
     8221 aaccgttcct aaagagatgg ttgagttgta aggggatgtc atcctattac ctccaaaaac
     8281 taattaaatc tatcataatc aatcagtttc aaaaagaaaa gtaggcacaa ataagtggta
     8341 taggcactaa aaagtaactc atttgttaac cctatcttgt ttctgttctc tctaatagtc
     8401 tataatgggt tataagttac aaaaagatac taagaggagc tgctgcctat gctgaaaaaa
     8461 agaccggctt gtcccgtaga aacggcctta tcggtaatcg ggaataaata gaaattatta
     8521 atattaagag acttgctaaa gggaccttgc gttttgggca gttgaagtcc tcaataggtt
     8581 tggtcagtca aaaggtactt actgcacaat taagggctat ggaagcagac ggattggttc
     8641 atcgggaagt gtatgcagaa gtgccacctc gggtggagta ttccttaaca gaaactgggt
     8701 tgagcttagc tcctgttatt gaagcgatgt cggattgggg ccaaacttac caagaaaaac
     8761 atgccgattt atttgaagaa ggctagagga aagagttgtc cgagcatact gagacttaga
     8821 gaagctgata gtttttaaaa aatgatatta tcaaattctt tacagtttga taaaattact
     8881 ttttttctat aaaaagactt gcgctcatct cacgaatatg ataatataat atcaagtctg
     8941 tttgagaaaa cagaagctca ggtcaagtaa gtgcacactt acaataacac agttgataat
     9001 ggggaaactc agagtcaaga aaaagaaaag caagccttgc attttgcaag gcttttttct
     9061 gtctttattt tggtctgcgc cgagcaaaat ctaaaaattt aaatttttcc agtttatggc
     9121 gactctcggt gaattggaat tggttattat tggaaaggta gactttggat ttgacggaaa
     9181 caacatgttg gtctgatcca aggtcaagta aaattttatc acgatcggtt atttggtcaa
     9241 tggtaacctc tttgagggca aagtcaatgg cgagatggag ttccttttcc aaatattgat
     9301 aaatagaatg ctctgcgatt tcccttgtca ttattggcac caaagtttta ctaaggtaat
     9361 caatgtctaa gacggaagcc acaccctcaa caacgcgttg gcgtgtaaca cgccagacca
     9421 agctgttttt gctaaaaccg gtcaattttg aaagtgtctc atccacaatc agtttatcaa
     9481 tggcaatgac gttggtctta gaatctagat ttgagtaaga gacgagttcc tgataactag
     9541 ttagttctga gatagggaac atgatctgat gatgtttaat cacttgggtg ccacgtcctt
     9601 gttttttgag gataagacct gcctttgtga gaagtgagag agccttgcgg acggtatctc
     9661 ggctagcttg gtattgttga ctcaattcta tttcagtagg taaaaaatcc ccttctttgt
     9721 aaaagtcttt gtttattttt gtttcgaggt ctttataaat acgttcatac tttgtcatag
     9781 ggtaaattac ctttccattt gtctattttt ttacagacaa caccttttat tttaccaaaa
     9841 taatggcttt tttggcacaa acaacttgca gacaaatttg caatcgatta caataaaggt
     9901 gtcaatcata ttttatctaa gaatttgaat atttcatttt gacgttgctt gttaaaagca
     9961 actagaacaa aggactaggg gatgtcacat gggaaaattt gaacaggatg ctaaaagtct
    10021 tctaactgct attggcggta aagaaaacat caaggctgtt acacactgtg caacgcgtat
    10081 gcgttttgtt ttgaatgata ataataaggc aaatgtcaaa gagattgaaa aaatctctgt
    10141 agttaaaggg acatttacca atgctgggca gtttcaggta atcattggta atgatgttcc
    10201 agttttttat aatgacttta cagctgtttc tggtattgaa ggggtgtcta aagaagctgc
    10261 caaatcagca gctaaaagta atcaaaatgc cttacaacgg gtgatgacca tgttggctga
    10321 gattttcaca cctattattc cggcgattat tgttgggggg cttattttag gtttccgtaa
    10381 tattttggag agtgtgcctt ttgaatttct tgggcagcag gtcgaaaaag ggaaattagt
    10441 ttttgatgca gctggggatc ctgtttggaa tacgattgtg agggtatctc ctttctggtc
    10501 aggggttaac catttcttgt ggttaccagg ggaagctatt tttcacttct taccagttgg
    10561 gattacttgg tctgtgacgc gtaagatggg aaccactcaa attttaggga ttgtccttgg
    10621 tatctgtttg gtgtcaccac aattattgaa tgcttatgcg gtggcaggaa cgcctgctgc
    10681 tgagattgcc aaaaactggg tttgggattt tggtttcttt accattaatc gtattgggta
    10741 tcaggcacag gttattccag cccttttagc tggtctgtcc cttgcttatc ttgaaacttt
    10801 ctggcgtaaa cggattccag aagtggtttc aatgattttt gtgccattcc tttctttgat
    10861 tccagctttg attttagcgc atacggtatt ggggccaatc ggttggacta ttggtaaagg
    10921 gatttccttt gttgtgttag ctggattgac tggtcctgtt aaatggctat tcggtgctat
    10981 ctttggtgcc ttgtatgctc cgctagttat tactggttta catcacatga caaatgccat
    11041 tgatacccaa ttaattgctg atactgcaac tcgtacaact ggtttgtggc caatgattgc
    11101 tctttcaaat atcgctcaag ggtcagccgt ttttgcttac tatttaatga atcgtcatga
    11161 agaacgtgag gctgaaatat cgcttcctgc agcaatttct gcttaccttg gggtaactga
    11221 gcctgcctta tttggggtta atgttaaata tgtttatccc tttgtagccg gaatgattgg
    11281 ctcaggtatt gcgggtctct tatcaacaac ctttaatgtt caggcaaatt ctattggtgt
    11341 tggtggctta ccaggtttca tggctatcaa tgtgaagtat atgattccat tcttcatctg
    11401 tatggcagta gccattgtgg taccgatgtt tttaaccttc tttttccgta aatcacatat
    11461 catgactaag acagaagatg aggctaaact acctgagaca cccgtttcgg aggctcctgc
    11521 agcaactgct ccacataaga ctatgcaagg gacagttatc actttaacaa gccctttaac
    11581 gggtgaagtt aaagcgttgt ctgaagctgt tgatcctgtc tttgcacagg gagttatggg
    11641 tcaaggtgct cttcttcaac cgacagaagg ggtgttagta gcgccttgtg atgctgaagt
    11701 atcggtcttg ttcccaacta aacacgctat ttgtttggtg acgactgaag gtttggaatt
    11761 attgatgcat attggcatgg acacggttaa cttagatggt caaggatttg aagctttggt
    11821 gaagcaaggt gatcaggtta aggctggaca aacattgatt caatttgata tagcagcaat
    11881 ttctgaagct ggatacgcca ctgaaacgcc tcttgtggtg actaatcaag atgcttttac
    11941 ggtaactgtt gaaggtagtt taccgcgtca gattaaggct aatgataagt tagcagtagc
    12001 gatgaaaaag taggtttact agggagaaaa cgttcaggaa ctgagatcag ttcctgaaac
    12061 tattttaggg aggaaaactc atgacaattg ataaaaagaa agtcgtctat caaatttacc
    12121 caaaatccta taaggacacg actggaaatg gtgtgggaga cttgcgaggg atcattgata
    12181 aattgcctta cttacaagaa ctaggaatag atatgatttg gttgaaccct ttctacccta
    12241 gtccacaacg agacaatggc tatgatgttt cagattatac ggcggttaac cctgattttg
    12301 ggactatggc tgattttgaa gatttggtaa aagctgctaa ggagcatcag attgagttaa
    12361 tgttggatat ggttttgaat cactgttcca cagaccacga gtggttccaa aaagctttag
    12421 caggagaccc ttattatcag gatttcttta tcttgagaga tcagccgact gattgggttt
    12481 ccaaatttgg tgggaatgct tgggcgcctt ttggagatac aggcaaatac tacttacact
    12541 tgtttgatgt gacacaggct gacttgaatt ggcggaaccc acatgttcgt gaggaattgg
    12601 ctaaagtggt taatttttgg cgagataaag gagtgaaggg gttccggttt gatgtgatta
    12661 atctgattgg gaaagatgaa gagctggtgg attgtccagt caatgatggt aagccagctt
    12721 atacggatcg tcctattact cacacttatc ttcatgatct caatcaagcc agttttggtc
    12781 aggatgattc gtttatgaca gtaggggaaa tgtctgccac gactattgac aactgtcttt
    12841 tatacacggc tcccgaacgt gaggagctat ccatggcttt taatttccac catctaaaag
    12901 ttgattatga gaacggtcag aaatggacta ttatggcttt tgattttgca gcgctgcgag
    12961 acttattcca tgcttggggt gaaggcatga gtcaaggcaa tgggtggaat gccttgttct
    13021 acaataacca tgatcaacca cgtgccctga atcgttttgt tgatgtaaca catttccgaa
    13081 acgaaggtgc gacgatgtta gcggcttcca tccatttgtc acgaggaacg ccttacattt
    13141 atatgggtga ggagattggc atgcttgatc cagactttga tagtatggat gattatgtgg
    13201 atgtggaaag tctcaatgct tactcaagct tactagtctc aggtaaaagt gcagaagaag
    13261 cctttgccat tatcaaggat aagtcaaggg acaatgccag aacaccaatg caatgggatg
    13321 ctagtgaaca tgctggcttt acgactggta agccttggtt agaggttagc aaatcttatc
    13381 gagacatcaa tgtcgaaaca gaaaaagagg gacgtatttt tcctttctac caacgcttga
    13441 ttgctttgcg gaaggaactc cctattattg ctgaagggga ttatcgggct gcttttaaag
    13501 atagtcagtc tgtctacgcc tttgaacgcc atttaggtga ccagtgtttg cttgttctca
    13561 atcatttcta tgctgatgag gtcgaactgg aattacctcc acgttatcaa catggacagg
    13621 tcttaatcag caactatgag aaagtttcta tttgtgaaaa agtgatactg aaaccttatc
    13681 agacacttgc tatcttagct gaaaactaac taaaagcctg aggttaggcc tcaggctttt
    13741 ggtgattgtc acgaaaaaag aagttttctc atatatttat ttttaaactc ttattttttc
    13801 taaataaaaa caattgagat aagttatttt agctaaattt tggtacaatg gaaaagatta
    13861 taagtagagt ttaagataaa gattctacaa atttaaaatg atataaggag atacgaatga
    13921 caacttatca agatgatttt taccaggctg tgaatggaaa gtgggctgaa acagcagtta
    13981 ttccagacga caagcctcga acaggtggat tttcagactt agcagatgaa attgaggcat
    14041 taatgctaga cactacagat gcttggctag ctggagaaaa tatccctgat gatgctattt
    14101 taaaaaattt tgtgaaattc catcgtttgg tggctgacta cgctaaacgt gatgaagttg
    14161 gagtaagtcc aattctccct ttaattgaag aatatcagtc cttaaaatct ttttcagaat
    14221 ttgttgctaa tatagcgaaa tatgaattgg caggtttacc aaatgaattt ccctttagtg
    14281 tggcaccaga ctttatgaat gctcagctga atgtgctttg ggcagaagca ccaagcattc
    14341 ttttgccaga tacaacatac tacgaagaag gcaacgaaaa agctgaggaa ttgcgtggta
    14401 tttggcgtca gtcgcaagaa aagcttttac ctcaatttgg tttttcaaca gaagaaatca
    14461 aggatctttt ggataaggta attgagctag ataagcaatt ggccaagtat gtcttgtctc
    14521 gtgaggaagg ctcagaatat gccaaattat accatcctta tgtgtgggct gattttaaaa
    14581 aactagctcc agagcttcct ttggatagca tttttgaaaa gattttaggc caagtacctg
    14641 acaaggttat tgttcctgag gaacgttttt ggacagaatt tgcagccact tattactctg
    14701 aagccaattg ggatttactc aaggctaatt tgattgtgga cgcggctaat gcttacaatg
    14761 cttacttgac ggatgatatt cgtgtggaat caggcgctta ttcgcgcgct ctttcaggaa
    14821 cacctcaagc tatggacaaa caaaaagcag ccttttattt ggcgcaagga ccgtttagcc
    14881 aagcgcttgg cttgtggtat gctggtcaaa aattctcccc agaagctaag gctgatgtgg
    14941 aaagtaaggt agcacgcatg attgaggttt ataagtctcg tctagaaacg gctgattggt
    15001 tagcaccagc cacacgtgaa aaagccatta ctaaattaaa tgttatcacg ccacatattg
    15061 gttacccaga aaaattacca gaaacctatg ctaaaaaagt gattgatgag agcttgtcat
    15121 tggttgaaaa tgcacagaac ttggctaaaa tcacgattgc tcacacttgg agtaaatgga
    15181 acaagccagt tgaccgtagt gagtggcata tgccagccca cttagtcaat gcttattatg
    15241 atcctcagca aaatcagatt gtctttcctg cggcaatctt acaagagcca ttttattctt
    15301 tagatcagag ttcttcagcc aattatggag gaattggtgc agtcattgcg catgagattt
    15361 cacatgcctt tgacaccaat ggtgcttcct ttgatgaaca tggtagccta aatgattggt
    15421 ggacacaaga agactatgct gcctttaaag agcgtacaga taagattgtg gcgcagtttg
    15481 acggcttaga gtcacatggt gctaaggtca acggtaaatt aacagtttca gaaaatgtcg
    15541 ctgatctagg tggggtagct tgtgctttag aagcggcaca atcagaagaa gacttctcag
    15601 cacgtgactt ctttattaac tttgcgacga tttggcgtat gaaggcccgt gaggaataca
    15661 tgcaaatgct agctagcatt gatgttcatg ctccgggtga actgcgaaca aatgtcacct
    15721 taaccaactt tgatgctttc catgagacct ttgatattaa agaaggcgat gctatgtgga
    15781 gagctccgaa agaccgtgtg attatttggt aattaggtag ttgataaacc ttcaaatgct
    15841 ttgtgattat aaaaatgact gattctgtga aacacaggat cagttttttg cttccttatt
    15901 ggtgtccgtt ttgacacaac aaaaagacaa ccctcaggaa agaaggttgc cttttttaga
    15961 cttatcagaa ataagtgatt agttgttaag ggcagcagcc atagtagctg caacttctga
    16021 ttcaaagtcg ttagcttttt tctcgatacc ttcaccaact tcaaaacgtg caaaagcaat
    16081 cgctttagcg tttactgagt caaggtaagc ttcaacagtt ttgctgtcgt ccatgatata
    16141 aacttgtgca agaagagtgt aagcttggtc aactttagtg ttgtcaagca tgaaacgatc
    16201 cattttacct gggatgattt tgtcccagat cttttctggt ttgccttcag cagcaagttc
    16261 agctttgatg tctgcttcag cagcagtaat cacgtcgtct gataattgag cttttgaacc
    16321 gtatttcaag aatggaagtg ctggtttgtc aaccattgca cgcgattcgt tgtcaagttc
    16381 gatagcgtgg ttcaattgag caagttcatc tttgatgaat tgtgcatcaa gctcagtgta
    16441 tgaaagaaca gttggtttca ttgcagcgat atgcattgat acttgtttag caagagcatc
    16501 gtcgccgcct tcgacaactg agataacccc gatacggcca ccattatgtt ggtaagcacc
    16561 gaagtgttgc tcatctgttt tttcaatcaa agcaaaacga cggaatgaga ttttttctcc
    16621 gatggtagca gttgcattaa cgtaagcttc agcaagagtt tcacctgaag gcataacaag
    16681 tgcaagtgct tcatcgttgt tagctggttt gccttcagcg ataactttag cagttgcgtt
    16741 taccaattca acgaattgag catttttagc aacaaagtct gtttcagcgt taacttcaac
    16801 aacagcagca acgttaccat gaacgtaaac gcctgttaaa ccttcagcgg caacacggtc
    16861 agctttttta gctgctttag ccattccttt ttcacgaaga agttcaacgg ctttgtccat
    16921 gtcaccatct gtttcaacaa gtgctttttt agcgtccata acgccagcac cagatttttc
    16981 acgtaattct tttacaagct tagctgtaat ttctgccatg tgtagtatcc tccaaatgat
    17041 atttgttttg gtttcaaaaa acgagacaga gcggtttgct ttctgccccg tttggttttc
    17101 gattgttaaa gacaaacaaa gtttgccata agagttagga actctgtgcc aattaagcgt
    17161 tgtcgccttc gacaacttca acgatttctt cgattgaatc tgcttgagtg tcagcttcaa
    17221 aagcaacgtc tgcatcttca ccttgacgac cttcgataat agcgtcagct aatttagcag
    17281 tgattaattt aacggcgcgg atagcgtcat cgttagctgg aatgatgata tcgatatcat
    17341 ctggatcagc gtttgtatca accatcgcta cgactgggat accaagtttt ttagcttctt
    17401 taacagcaat ttgttcttta tgtgggtcaa caacatacat cacgtctggg atacgaggca
    17461 tatcttcgat accgcccaag aatttttcaa gacgagcgcg ttgtttgtta agaagtgcaa
    17521 cttctttctt aggaagaacg tcaaaggttc ctttttcttc catacgtttg atttctttca
    17581 aacgagcgat acgtttttgg atagttcccc agttggtaag cgttccaccc aaccaacggt
    17641 ggttgatgaa gtattggcct gcacgcgttg cttcgtcagc aactgcttca gcagcttgtt
    17701 ttttagtacc aacgaacaag atgacagcat cgtttgctgc agcatcacga acaaattcgt
    17761 aagcttggtc agctaatttt acagtttgtt gaagatcgat aacgtggata ccgttacgct
    17821 ctgtgaagat gtatttagcc atcttagggt tccagcgacg agtttggtga ccaaagtgaa
    17881 caccagcctc aagaagttgt ttcattgaaa ttactgccat gagtagtttc tcctttataa
    17941 aatgtttttt cctcttccag acttcgactt gcaggctaac ctagcggcaa caagcccaca
    18001 attggtctag aatgagtatt tgccgtctac acgaccctac tatattatca aaaaaagagg
    18061 ttaaaagcaa ggagaaatgc tatgaa
//
LOCUS       DAUCXI010000037        17679 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.037, whole genome shotgun sequence.
ACCESSION   DAUCXI010000037 DAUCXI010000000
VERSION     DAUCXI010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17679
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.037"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            130..936
                     /locus_tag="VGY43_001366"
     CDS             130..936
                     /locus_tag="VGY43_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEQ4302543.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKIPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPAPII
                     KAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLK"
     gene            1139..2494
                     /gene="dnaA"
                     /locus_tag="VGY43_001367"
     CDS             1139..2494
                     /gene="dnaA"
                     /locus_tag="VGY43_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEQ4302544.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
     gene            2649..3785
                     /gene="dnaN"
                     /locus_tag="VGY43_001368"
     CDS             2649..3785
                     /gene="dnaN"
                     /locus_tag="VGY43_001368"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEQ4302545.1"
                     /translation="MIQFSINRTLFIHALNATKRAISTKNAIPILSSIKIEVTSTGVT
                     LTGSNGQISIENTIPVSNENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQH
                     QVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRP
                     ILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAME
                     RAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYL
                     IESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRTN"
     gene            3860..4057
                     /locus_tag="VGY43_001369"
     CDS             3860..4057
                     /locus_tag="VGY43_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEQ4302546.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVLQP"
     gene            4387..5502
                     /gene="ychF"
                     /locus_tag="VGY43_001370"
     CDS             4387..5502
                     /gene="ychF"
                     /locus_tag="VGY43_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEQ4302547.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            5572..6141
                     /locus_tag="VGY43_001371"
     CDS             5572..6141
                     /locus_tag="VGY43_001371"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEQ4302548.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            6144..9647
                     /gene="mfd"
                     /locus_tag="VGY43_001372"
     CDS             6144..9647
                     /gene="mfd"
                     /locus_tag="VGY43_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEQ4302549.1"
                     /translation="MDILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLRNPKSQGVLIVSLSGLRTLLPNPDVFTKSQIQLTVGENYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GIFINPASDLIFEASDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFTDNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYERLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEREIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQIGSLSKYVSADGKEPKINKLNDGRFQKIKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERVRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVAELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDILVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYIADERQK
                     IDIYKRIREIRSREDYLNLQDELMDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
     gene            9809..10081
                     /locus_tag="VGY43_001373"
     CDS             9809..10081
                     /locus_tag="VGY43_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEQ4302550.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTNIKLN
                     DHIEISFGNKLLTVRVIEIKDSTKKEDALKMYEIISETRITLNEEA"
     gene            10068..10439
                     /locus_tag="VGY43_001374"
     CDS             10068..10439
                     /locus_tag="VGY43_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEQ4302551.1"
                     /translation="MKKPSIVQLNNHYIKKENLKKKFEEEESQKRNRFMGWILVSMMF
                     LFILPTYNLVKSYVDFEKQNQQVVKLKKEYNELSKRTKKEKQLAERLKDDNFVKKYAR
                     AKYYLSREGEMIYPIPGLLPK"
     gene            10574..11860
                     /locus_tag="VGY43_001375"
     CDS             10574..11860
                     /locus_tag="VGY43_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEQ4302552.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQIPSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFSFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIPDNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            11857..13143
                     /gene="tilS"
                     /locus_tag="VGY43_001376"
     CDS             11857..13143
                     /gene="tilS"
                     /locus_tag="VGY43_001376"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEQ4302553.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLTIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNYSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDLPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQTA
                     KQGYYYLKKDYYIFIDKFSFKITKIVPKTELVKEEKMLEYDSNLCYRDYYFSFMPKSN
                     EDQGQVSIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIIGEQ
                     DEQIIFVLIGNKTYLRKACKHDIMLAKLYIDKLEKG"
     gene            13148..13690
                     /gene="hpt"
                     /locus_tag="VGY43_001377"
     CDS             13148..13690
                     /gene="hpt"
                     /locus_tag="VGY43_001377"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEQ4302554.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            13712..15691
                     /gene="ftsH"
                     /locus_tag="VGY43_001378"
     CDS             13712..15691
                     /gene="ftsH"
                     /locus_tag="VGY43_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEQ4302555.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     AYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
     gene            16017..17408
                     /locus_tag="VGY43_001379"
     CDS             16017..17408
                     /locus_tag="VGY43_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEQ4302556.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLIFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     YLAYGYTHSIENK"
BASE COUNT         6203 a         2671 c         3200 g         5605 t
ORIGIN      
        1 gaggaactac aaagaaaaaa gcagatatca aattaacaaa aactactcaa gatttgacta
       61 aaacgcagta aacaagctac ctaaatacta ttacatttta tcacataaaa cagtccaaag
      121 gactgtttta tgtttcttat tctatccagg aactccctta tgacaaaaga attattgata
      181 gacctaccaa ttgaagatat tgttacaaat ccctatcagc caaggataca atttaatcaa
      241 agagaactcc aagacctagc aacttctatt aaatcaaacg gcctcattca acctattatt
      301 gttcgaaaat ctgacatttt tggctatgag ttagttgctg gagaacgacg acttaaagct
      361 tcaaaaatgg ctggtctaaa aaaaattcca gctatcatca agaagatctc tacactcgag
      421 agcatgcaac aagctatagt tgaaaattta caacgttcta accttaacgc tatcgaagaa
      481 gctaaagcct atcagttatt ggttgaaaaa aaacacatga ctcacgatga gattgctaaa
      541 tatatgggaa aatcaagacc ttatattagc aataccttac gtctgttaca actcccagca
      601 cctatcatta aagcaattga agaaggaaaa attagtgcgg gacacgcgcg tgctctttta
      661 actttgagtg atgataagca acaactgtac ctcactcata aaatacaaaa tgaaggccta
      721 agtgttaggc aaattgagca actggttact tctactccaa gttcgaagct atctaaaaaa
      781 actaaaaata tttttgccac ttctttagag aaacaattgg ctaaatcatt gggactctct
      841 gtcaatatga agctgacagc aaaccatagt gggtaccttc agatatcttt ttccaatgat
      901 gatgaattaa acagaattat caacaagcta aagtagcttg ttgatattct gttttttctt
      961 ttttagtttt ccacataaaa aatagttgaa aacaatagcg gtgtcacctt aaaatggctt
     1021 ttccccaggt tgtggagaac ccaaattaac agtgttaatt tattttccac aggttgtgga
     1081 aaactagaat agtttatggt agaatagttc tagaattatc cacaagaagg aacctagtat
     1141 gactgaaaat gaacaaattt tttggaacag ggtcttggaa ttagctcaga gtcaattaaa
     1201 acaggcaact tatgaatttt ttgttcatga tgcccgtcta ttaaaggtcg ataagcatat
     1261 tgcaactatt tacttagatc aaatgaaaga actcttttgg gaaaaaaatc ttaaagatgt
     1321 tattcttact gctggttttg aagtttataa cgctcaaatt tctgttgact atgttttcga
     1381 agaagaccta atgattgagc aaaatcagac caaaatcaat caaaaaccta agcagcaagc
     1441 cttaaattct ttgcctactg ttacttcaga tttaaactcg aaatatagtt ttgaaaactt
     1501 tattcaagga gatgaaaatc gttgggctgt tgctgcttca atagcagtag ctaatactcc
     1561 tggaactacc tataatcctt tgtttatttg gggtggccct gggcttggaa aaacccattt
     1621 attaaatgct attggtaatt ctgtactatt agaaaatcca aatgctcgaa ttaaatatat
     1681 cacagctgaa aactttatta atgagtttgt tatccatatt cgccttgata ccatggatga
     1741 attgaaagaa aaatttcgta atttagattt actccttatt gatgatatcc aatctttagc
     1801 taaaaaaacg ctctctggaa cacaagaaga gttctttaat acttttaatg cacttcataa
     1861 taataacaaa caaattgtcc taacaagcga ccgtacacca gatcatctca atgatttaga
     1921 agatcgatta gttactcgtt ttaaatgggg attaacagtc aatatcacac ctcctgattt
     1981 tgaaacacga gtggctattt tgacaaataa aattcaagaa tataacttta tttttcctca
     2041 agataccatt gagtatttgg ctggtcaatt tgattctaat gtcagagatt tagaaggtgc
     2101 cttaaaagat attagtctgg ttgctaattt caaacaaatt gacacgatta ccgttgacat
     2161 tgctgccgaa gctattcgcg ccagaaagca agatggacct aaaatgacag ttattcccat
     2221 cgaagaaatt caagcgcaag ttggaaaatt ttacggtgtt accgtcaaag aaattaaagc
     2281 tactaaacga acacaaaata ttgttttagc aagacaagta gctatgtttt tagcacgtga
     2341 aatgacagat aacagtcttc ctaaaattgg aaaagaattt ggtggcagag accattcaac
     2401 agtactccat gcctataata aaatcaaaaa catgatcagc caggacgaaa gccttaggat
     2461 cgaaattgaa accataaaaa acaaaattaa ataacatgtg gaaaagaata tcttttatga
     2521 aatagttatc cacaagttgt gaacaaccat ttagtcttgg attctctcgt ttatttagag
     2581 ttatccacta tatacacaag acctactact actacttatt attatactta ttaaataaag
     2641 gagttctcat gattcaattt tcaattaatc gcacattatt tattcatgct ttaaatgcaa
     2701 ctaaacgtgc tattagcact aaaaatgcca ttcctattct ttcatcaata aaaattgaag
     2761 tcacttctac aggagtaact ttaacagggt ctaacggtca aatatcaatt gaaaacacta
     2821 ttcctgtaag taatgaaaat gctggtttgc taattacctc tccaggagct attttattag
     2881 aagctagttt ttttattaat attatttcaa gtttgccaga tattagtata aatgttaaag
     2941 aaattgaaca acaccaagtt gttttaacca gtggtaaatc agagattacc ttaaaaggaa
     3001 aagatgttga ccagtatcct cgtctacaag aagtatcaac agaaaatcct ttgattttaa
     3061 aaacaaaatt attgaagtct attattgctg aaacagcttt tgcagccagt ttacaagaaa
     3121 gtcgtcctat tttaacagga gttcatattg tattaagcaa tcataaagat tttaaagcag
     3181 tagcgactga ctctcatcgt atgagccaac gtttaatcac tttggacaat acttcagcag
     3241 attttgatgt ggttattcca agtaaatctt tgagagaatt ttcagcagta tttacagatg
     3301 atattgagac cgttgaggta tttttctcac caagccaaat cttgttcaga agtgaacaca
     3361 tttcttttta tacacgcctc ttagaaggaa attatcccga tacagaccgt ttattaatga
     3421 cagaatttga gacggaggtt gttttcaata cccaatccct tcgccacgct atggaacgtg
     3481 ccttcttgat ttctaatgct actcaaaatg gtactgttaa gcttgagatt actcaaaatc
     3541 atatttcagc tcatgttaac tcacctgagg ttggtaaggt aaacgaggat ttagatattg
     3601 ttagtcagtc tggtagtgat ttaactatca gcttcaatcc aacttacctt attgagtctt
     3661 taaaagctat taaaagtgaa acagtaaaaa ttcatttctt atcaccagtt cgaccattca
     3721 ccctaacacc aggcgatgag gaagaaagtt ttatccaatt aattacacca gtacgaacaa
     3781 actaagtaag aaaaagctcc cttttaggag tttttttgtt attataaata ttaacgataa
     3841 tataagtgga gaaaagggaa tgtatcaaat tggatcattt gttgaaatga aaaaacctca
     3901 tgcttgtgta attaaagaaa ctggtaaaaa ggctaatcaa tggaaggtac tgagagtagg
     3961 agctgatatt aaaattcagt gtactaactg tcagcatgtg attatgatga gtcgttatga
     4021 ttttgagcga aaattaaaaa aagtactgca accatgaaag tccttttaaa taaataattc
     4081 tagctatatt tgcaaccaat actttcctaa aaaattgcta gtatgccgtt ggaaaattag
     4141 ctattctaat gttatcgaaa gaagaaagat ggccattgac aatgacgaaa gttgtagcac
     4201 agttacttag tttctcggca aactatatca aaatgagaat aatacaccaa actttgataa
     4261 tttaaatgaa ggtgaaagag tggcataatg ataagcaaat ctgaaatttt cttcttattc
     4321 ataccgcttt ttcttctatt ttttggtata ataatcttga ttgaaatttg aatggagatt
     4381 cgctaaatgg ctttaacagc aggtattgta ggcttaccaa atgttggtaa atcaacctta
     4441 tttaacgcaa ttacaaaagc aggagcagaa gctgctaatt atccttttgc gactattgat
     4501 cccaatgttg gtatggtaga ggttccagat gagcgtctgc aaaaattgac agaattgatt
     4561 acacctaaaa aaacagttcc gacaaccttt gaatttactg atattgcagg tatcgttaaa
     4621 ggtgcttcta gaggggaagg tctaggaaat aaatttttag ctaatattcg tgaagtcgat
     4681 gctattgttc atgtggtacg tgcttttgat gatgaaaatg tcatgcgtga acaaggtcgt
     4741 gaggatgctt tcgttgatcc tatagcagat attgacacta ttaatcttga attaatctta
     4801 gctgatttag agtcaatcaa taaacgttat gcgcgtgttg aaaaaatggc acgaactcaa
     4861 aaagataaag aatcagtagc agagttcaat gttttgcaaa agattaaacc tgttttggaa
     4921 gatgggaaat cagctaggac aattgagttt acagaagatg aagcaaaagt tgttaaaggt
     4981 ctctttttat taacaactaa acctgtttta tatgtagcta atgtcgatga agataaagtt
     5041 gctaatccag atggtattga ttatgtcaaa caaattcgtg actttgcagc tactgaaaat
     5101 gctgaagtag ttgttatctc agcgcgtgca gaagaagaaa tttcagagct tgacgatgag
     5161 gataaagaag aatttttgga agctatcggt cttactgaat caggcgttga taaattaacc
     5221 agagcagctt atcatctctt aggccttgga acctatttta cagcaggtga aaaagaggtt
     5281 cgtgcttgga cgtttaagcg tggtataaaa gctccacaag ctgctggtat tatccattca
     5341 gattttgaaa gaggctttat tcgtgcagta accatgtctt atgatgatct aatgacctac
     5401 ggttcagaaa aagccgtcaa agaagctgga cgcttgcgtg aagaaggaaa agaatatgtt
     5461 gtccaagatg gggacatcat ggaattcaga tttaatgtgt aattatatta aaacaatatc
     5521 agaaggttgg aagaacattc cagccctttt ggcattttag aaagagaaaa tatggtaaaa
     5581 atgattgttg gtctgggaaa tccaggctct aaatatgaaa aaacaaagca caatattggt
     5641 tttatggcta ttgacaatat tgtcaagaac cttgacgtta cctttacaga tgataaaaat
     5701 tttaaagcac agataggaag tacttttatt aatcatgaaa aagtttactt tgtgaaacct
     5761 actactttta tgaataatag cggcatagca gtaaaagcat tactaaccta ctataatatt
     5821 gacataacag atttaattgt tatctatgat gatttagaca tggaagtcag taaattacgt
     5881 ttacgtagta agggttcagc aggaggacat aatggcatta agtcaatcat tgcccacatt
     5941 ggaactcagg aatttaaccg aatcaaagtt ggtattggac gacctttaaa aggtatgact
     6001 gttattaacc atgtgatggg ccaattcaat actgaagata atattgctat ttcgttaact
     6061 cttgacagag ttgtcaatgc tgtcaagttt tatttacaag aaaatgattt tgaaaaaaca
     6121 atgcagaaat ttaatggata atcatggata ttttagaatt atttagtcag aataagaaag
     6181 tccaatcctg gcactctgga ttaaccacct taggaagaca actggtaatg gggttatcgg
     6241 gttcaagtaa agcattggct atagcttccg cttatttaga tgatcaaaaa aaaatagttg
     6301 tggttacatc aactcaaaat gaggttgaaa aattagccag cgatttatct agtttacttg
     6361 atgaagaact tgttttccaa ttttttgcag acgatgtggc tgcagcggaa tttatctttg
     6421 cgtcaatgga taaagctcta tcaagaatag aaaccctgca atttttaagg aatcctaaat
     6481 ctcagggcgt tttaattgtt agtttatcag gcttaagaac tttattgcca aacccagatg
     6541 tttttacaaa gagtcagatt caactaacag ttggagaaaa ttatgatagt gatactctta
     6601 ctaaacaact gatgacaatt ggatatcaga aggtctcaca ggttattagt ccgggagaat
     6661 ttagccgtcg aggggatatt ttagatatct atgagattac acaagaattg ccttatcgat
     6721 tggaattttt tggtgatgat attgatagta ttaggcaatt tcatccagaa actcaaaaat
     6781 cttttgaaca actagaaggt atttttatta atccagcaag tgatcttatt tttgaggcta
     6841 gtgattttca acgtggcatt gagcaattag aaaaggctct acaaacagca caagatgata
     6901 aaaaatctta tttagaagat gtattagctg tttcaaaaaa cggttttaaa cataaggata
     6961 tccgtaaatt tcaatcatta ttttatgaaa aagagtggtc attattagat tatattccta
     7021 agggaacgcc aatctttttt gatgattttc aaaaactagt tgataaaaat gcaagatttg
     7081 atttagagat tgctaatctc ttgacagaag atttacagca aggaaaggct ctttccaatc
     7141 ttaactactt tacagataat tatcgagagc ttaggcacta taagccagcg accttctttt
     7201 caaattttca taagggactt ggaaatatca aatttgatca gatgcatcag ctaactcagt
     7261 atgccatgca ggaatttttt aatcaatttc ctttgttgat tgatgagatt aaacggtatc
     7321 aaaaaaatca aacaacggtt attgtacagg tagagtctca gtatgcttac gaacgacttg
     7381 aaaaatcttt tcaagattac caatttcgcc ttcctttagt gagtgctaat caaattgttt
     7441 cacgtgaatc acaaattgta attggagcta tctccagtgg tttttatttt gctgatgaaa
     7501 agttagcgtt aatcacagag cgtgaaattt atcataaaaa gatcaaacga cgcgctagac
     7561 gatctaatat tagcaatgct gagcgtttga aagattacaa tgagttagca gtaggtgatt
     7621 acgtggttca taatgtccat ggtatcggtc gctttcttgg aattgaaacg attcagattc
     7681 agggaatcca tcgagattat gttactattc aatatcaaaa ttcagaccgt atttctcttc
     7741 caattgacca aattggtagc ttatcaaagt acgtttctgc tgatggaaaa gaacctaaaa
     7801 ttaataaact caatgatggt cgttttcaaa agataaagca aaaggtcgct agacaagtag
     7861 aggatattgc tgatgacctt ctaaaattat atgctgaaag aagtcagcaa aaaggatttt
     7921 cattttcacc agatgatgac ttgcagcgcg cttttgatga tgattttgct tttgtagaaa
     7981 cagaagatca acttaggtct ataaaggaaa ttaaagctga tatggagagc atgcagccta
     8041 tggatcgtct tttagtaggc gatgtaggat ttggtaagac agaagtagct atgagggcag
     8101 cctttaaagc ggtgaatgat cacaaacaag tagctgtctt agttccaacc acagtcttgg
     8161 cccagcagca ttatgaaaac ttcaaagcac gctttgaaaa ttaccctgtt gaggttgacg
     8221 tcttaagtcg tttccgtagt aaaaaagagc aagctgaaac actagaacgt gtacgaaaag
     8281 gtcaaattga cattattatc ggaacccatc gactcctatc aaaagatgtg gtcttttctg
     8341 atttaggatt gattgtgatt gatgaggaac aacggtttgg tgttaagcat aaagaaactt
     8401 taaaggaatt aaaaactaag gttgacgtct taaccttaac agctactccg attcctagaa
     8461 ccttacacat gtctatgtta ggtatccgag atttatcggt tattgagacc ccaccaacca
     8521 atcgttatcc tgttcaaacc tatgttttgg aaaataatcc aggtctcgtt agagaagcta
     8581 tcattcgtga aatggatcgt ggaggacaaa ttttttacgt ttacaataaa gttgacacta
     8641 ttgaaaagaa agttgcagag ctacaagaat tagtcccaga agcttctata ggttttgttc
     8701 atgggcaaat gagtgaaatt caacttgaaa ataccttgat tgactttata aatggtgatt
     8761 atgatatcct tgtggctaca acaatcatcg aaacaggagt tgacatttct aatgtaaaca
     8821 ctttgtttat tgagaatgct gatcatatgg gattgtcaac attgtatcaa ctgagggggc
     8881 gcgtcggaag aagtaatcgt attgcctatg cttacctgat gtatcgtcct gataaggtcc
     8941 taacagaagt ctctgaaaaa cgtttagagg ctattaaagg ctttactgaa ttaggttcag
     9001 gcttcaagat tgctatgcga gatttgtcta tacgaggagc aggtaatatt ttaggagctt
     9061 ctcaaagtgg ctttattgat tcggtcggtt ttgaaatgta ttctcagtta ttggaacagg
     9121 ctattgctag caagcaagga aaaacgactg ttcgccaaaa aggtaatact gaaatcaatc
     9181 ttcagattga tgcctattta ccagatgatt atattgcaga tgagcgccaa aaaattgaca
     9241 tttacaagcg tattcgagaa attcgatcaa gagaagatta tctcaatttg caagatgagc
     9301 ttatggatcg ttttggagag tatcctgatc aagttgccta tttgttagag atagctctgc
     9361 taaaacatta tatggacaat gcctttgcgg aattagttga acgcaaaaat aatcaggtca
     9421 ttgttcgatt tgaagtaact tctttaactt atttcttgac tcaggattat ttcgaagcct
     9481 tatcgaaaac ccatcttaaa gctaaaatta gtgaacatca ggggaaaatc gatatcgtct
     9541 ttgacgttcg ccatcaaaaa gattatagaa ttttagaaga attgatgtta tttggagaaa
     9601 ggcttagtga gataaaaatc agaaaaaaca attcagtttt taaataataa tttgaaacaa
     9661 cttttagact gaatagtatt aatgacaatg gaacgaacta gctctttata cttttgtcaa
     9721 aaatctaaga tctttgctgc gaaattagga tcttttctac catttaaaaa ataaaaatga
     9781 taaaatgaag aggattgtag gagaaattat gagactagat aaatatctaa aggtatcgcg
     9841 ccttattaaa cgtcgttcag tagcaaaaga agttgcggat aagggacgaa ttaaagttaa
     9901 tgggatactt gctaaaagtt caacgaatat aaaactaaat gatcacattg aaattagttt
     9961 tggaaataaa ttactgacag taagagtcat tgaaataaaa gatagtacaa aaaaagaaga
    10021 tgctcttaag atgtatgaga taatcagtga aacaaggata acattaaatg aagaagccta
    10081 gtattgttca attaaataac cattatatta agaaagagaa tctcaaaaaa aaatttgaag
    10141 aagaagaatc tcaaaaaaga aatcgtttta tgggatggat ccttgtaagt atgatgtttt
    10201 tatttatttt gccaacttat aatcttgtca aaagttatgt tgattttgaa aagcaaaatc
    10261 aacaggtggt taaattaaaa aaagagtata atgaattgtc aaagaggaca aaaaaagaaa
    10321 aacaattagc agaacgacta aaagatgata attttgtcaa aaaatatgct agggcaaaat
    10381 actatttatc gcgtgaagga gaaatgattt atcctattcc aggactatta ccaaaatgat
    10441 gatggacaat attgtaaaaa aaatagaagc atttcttgct ttttctgata aaaaattagc
    10501 agagctgcaa caggaaaatc aaaaagttaa agaagaaagt cagtatattc aaaaaaacta
    10561 gaaaggagtc aatatgagaa aattattagc ggctatgtta atgacttttt ttctgactcc
    10621 tttaccagtg attagtacag aaaaaaaact tatattttca aaaaatgctg tttatcaatt
    10681 gaaacaagat gtcgttcaat caacacaatt ctataatcaa ataccctcta atccaaatct
    10741 ttatcaagaa acgtgtgcct ataaagacag tgatttaact ctaccagcag gaagattagg
    10801 tgtaaatcaa ccattactta ttaaatcgct tgtgcttaac aaagaatctt taccggtttt
    10861 tgagttagct gatggtacct atgttgaggc taatcgacaa ttgatttatg acgatattgt
    10921 acttaatcaa gtagatatag atagctattt ttggacacaa aagaaactta ggctttattc
    10981 agccccttat gttttaggta cgcaaacaat tccttcttct ttttcatttg ctcaaaaagt
    11041 tcatgccact caaatggcac aaacaaacca tggaacttat tatcttattg atgataaggg
    11101 ctgggcatca caagaagatc tagttcaatt tgataaccgc atgttaaaag tccaggaaat
    11161 gctcttacaa aaatataata acccaaatta ttcaattttt gtaaagcaac tcaacacaca
    11221 aacaagtgct ggtattaatg ctgataaaaa aatgtatgct gcaagtatct cgaagttagc
    11281 accactttat attgttcaaa aacaattaca aaaaaagaaa ttagcagaga ataaaacttt
    11341 gacttatact aaagatgtta atcattttta tggagactat gatccattag gaagtggtaa
    11401 aattagtaaa atacctgata ataaagatta tcgtgttgaa gacctactga aagctgtagc
    11461 acaacaatcg gataatgtag caactaatat tttaggttat tatctatgtc atcagtatga
    11521 taaagctttc cgctcagaga taaaagcttt atcaggtatc gattgggata tggagcagcg
    11581 cttattaact tctcgttcag ctgcaaatat gatggaagct atttatcatc aaaaaggcca
    11641 aattatttct tacctttcaa ataccgaatt tgatcaacaa cgtatcacaa aaaatattac
    11701 tgttccagtt gcacataaaa ttggtgatgc ttatgattat aaacatgacg ttgctattgt
    11761 ttacggtaat actccattta ttttgtctat ttttacaaat aaatcaacct atgaagatat
    11821 tacggctatt gcagatgacg tttatggtat tttaaaatga tgacctatca agaaattttt
    11881 aatgaaataa aaaataaagc ctactttaaa aatcatagac atgtgttaat agccgtatct
    11941 ggtggagtag attcaatgaa tttattgcac tttttgtacc tgtttcaaga caaattgaca
    12001 attcgtattg gtattgctca tgttaatcac aaacaaagat cagaatcaga ttcagaagaa
    12061 gcttatttaa agtgttgggc taaaaaacat gacataccta tttatgtttc taattttgaa
    12121 ggaatatttt cagaaaaagc agcacgtgat tggcgctatg ctttttttaa gagtattatg
    12181 ttaaaaaata actattcagc tttagtaaca gctcaccatt cagatgatca agcagaaact
    12241 attttgatga ggctaattag aggaagccga ttgaggcact tgtcgggtat aaaaagcgtg
    12301 caaccatttg ccaatggtca acttataaga ccttttttaa ctttctcaaa aaaggacttg
    12361 ccagaaattt ttcattttga agattcttca aatagagaat tatcattttt aagaaataga
    12421 gttagaaata attatttacc actgttaaag caggaaaatc ctaggttcat tcagggatta
    12481 aatcaattag cacttgaaaa tagcttactt tttcaagctt ttaaggagct aacaaatcat
    12541 attactacca ctgatttaac agaatttaat gagcaatcta agtcaattca atactttttg
    12601 ttacaagatt atttagaagg ttttccagat ttagatttaa aaaaatctca atttactcaa
    12661 ttattgcaaa ttatccaaac tgctaaacaa ggctattatt atctcaaaaa agactattat
    12721 atattcattg ataaattctc ttttaaaatt acaaaaatcg ttcctaagac tgagttagtt
    12781 aaagaagaaa aaatgttaga atacgatagt aacttatgct acagagatta ttatttttca
    12841 tttatgccaa aaagtaacga agatcaagga caggtaagta tacctttatt tagtttatcg
    12901 tctattaaat taagaagtcg ccaatctgga gattatattt cttttggtca cttttcaaaa
    12961 aaaataagac gtttatttat agatgaaaaa ttcacaatag ctgaacgtca aaatgctatc
    13021 attggagagc aagatgagca gattatattt gtattgatag gtaataaaac ttatttgaga
    13081 aaagcttgta aacatgatat aatgttggct aaactgtata ttgataaatt agaaaaaggg
    13141 tgacagcatg ctcgagcaag atattcaaaa aattctttac tctgaaaatg atattattcg
    13201 gaaaactaaa aaattaggag aacaattaac aaaagattat caagaaaaaa atccgcttat
    13261 gattggtgta ttaaaaggat cagttccttt tatggcagaa ctaatgaaac acatcgatac
    13321 tcatgttgaa attgatttta tggtagtatc aagttatcat ggcggtacat ctagcagtgg
    13381 tgaagttaaa attttaaaag atgtagatac caatattgaa ggaagagata tcataattgt
    13441 tgaagatatt attgacaccg gtcgcacctt aaaatattta cgagatatgt ttaagtaccg
    13501 taaagctaat actatcaaaa ttgcaacact gtttgataaa cctgaaggtc gtgttgttaa
    13561 aattgaagca gattatgttt gttacaatat tccaaatgaa tttatcgtag gctttggttt
    13621 agattacgca gaaaattatc gcaatcttcc ttacgtaggt gtattaaaag aagaagtcta
    13681 ttcaaaatag aaaaaggtca atgtttactg tatgaaaaat aataaaaata atggttttgt
    13741 taaaaattct tttatatata tattgatgat tattgttgtc atcacaggat ttcaatttta
    13801 tcttaaggga accagcacac aaagccaaca gattagttat tccaaattaa ttaaacatct
    13861 taaggctgga gatataaaat ctttaagtta tcagcctagc ggtagtatta ttgaagttaa
    13921 agggaaatat gagaaacctc aaaaagtgac agttaattca ggactatcat ttttaggtgg
    13981 aagagcttca acacaggtaa cagagttctc atctttagta ttacctagtg ataccatctt
    14041 gaaagaaatg acagcagcag ctgataaaaa tggaacagag cttacagtta agcaggaaag
    14101 ttcaagtggt acttggatta ccttcttaat gagcttttta cctattgtta tttttgctgc
    14161 tttcatgatg atgatgatga atcaaggtgg tggaggagct cgtggtgcta tgagtttcgg
    14221 caaaaataag gcaaaatctc aatcaaaagg tgatgttaaa gtgagattta cagacgttgc
    14281 tggtgccgaa gaagaaaaac aagaattagt agaagttgtt gattttttga aaaatcctaa
    14341 aaaatataaa tcactaggag cacggattcc agcgggagtt cttctagagg ggcctccagg
    14401 tactggtaaa acattactag ctaaagctgt agcaggtgaa gctggagtgc catttttcag
    14461 tatttcaggt tcagattttg tcgaaatgtt tgtcggtgta ggtgctagtc gtgttcgttc
    14521 tttatttgag gatgctaaaa aagctgagcg tgcgatcatc tttatcgatg aaattgacgc
    14581 tgtaggtcgt cgtcgtggtg ctggcatggg aggcggtaac gatgaacgag aacagaccct
    14641 taaccaatta ctcattgaaa tggatggttt tgagggtaat gagaacatta tcgttattgc
    14701 tgcaactaac cgtagtgatg ttttagatcc agctttacta agaccaggtc gttttgatcg
    14761 taaggtttta gttggtcgcc ctgatgttaa aggacgtgaa gccattttac gtgttcatgc
    14821 taaaaataaa ccacttgcaa atgacgttaa tttgaaagta gtagcccaac agactccagg
    14881 ttttgtaggt gctgatcttg aaaatgtttt aaatgaagct gcgttagttg ctgctcgcag
    14941 aaataaaatt aaaattgatg ctagtgatat tgatgaagct gaagatcgtg ttattgctgg
    15001 accatcaaag aaagatcgca ctatttcgca aaaagagcga gaaatggttg cttatcacga
    15061 agctggtcat actattgttg gtttagtttt atctaatgcg cgtgtagttc acaaggtaac
    15121 tattgtacct cgtggacgag caggtggtta tatgatcgct cttccaaaag aagatcaaat
    15181 gcttctttct aaagaagatc tgaaagagca attagcagga ttgatgggtg gtcgtgttgc
    15241 tgaagaaatt gtttttaatg ctcaaacatc aggtgcgtca aatgactttg agcaagctac
    15301 tcagatagca agggccatgg ttacggaata tggtatgagt gaaaagcttg gaccagttca
    15361 atatgaaggt aaccatgcga tgatgccagg acagatctct cctgaaaaag cttactctgc
    15421 ccaaacagct caaatgattg atgatgaggt tcgtgaactc ttaaatcaag ctcgtaatca
    15481 agcagctgat atcatcaatg agaatcgaga tactcataaa ttgattgctg aagctcttct
    15541 caaatatgaa actctagacg ctgcacaaat taaatcaatt tatgaaactg gtaaaatgcc
    15601 agttgattta gaaactgatg ataatgaagc tcatgcgtta tcttatgacg aaattaaaaa
    15661 taaaatgaca gaatctgaat ctgcagaatg agataaaaaa gctgaactta tagattaagt
    15721 tcagcttttt tatcaacaca atatccttgt aaacgttatg aattgtaata ggtgcctaat
    15781 tgctagaaat gagaagatga catacttttt ttctttatta cttaaagtga gaaagacttt
    15841 ggtatttaaa actagaaaat tgttaaagcc atttgaaaaa atctattagt gttttcttag
    15901 aataatagaa gaacagaaga tagcaaaagt ttcagtcaac caataagatg aaatttacaa
    15961 tcattactaa ctatgataca cttagtagaa aatcatttac tatagaaggt gataacatga
    16021 ctatttttcg taaaaaaaag aaatattcca ataaaacaga aatgcaaagg cacttcaaag
    16081 ttattgattt aattttttta ggcctaggtt caatggttgg aacaggtatc tttacagtta
    16141 ctggcatagg cgctgctaag tatgcaggtc ctgctttaac aatatcgatt atcatttccg
    16201 cgattgctat tggaatttta gccttatttt atgcagaatt tgcgtctcgt atgccttcta
    16261 acggtggtgc ttatagttat gtttatgcaa ccttgggaga gtttccagca tggcttgttg
    16321 gctggtatat tattatggaa tttttaacag ctatatctag tgttgctgtt ggctggggaa
    16381 gttatttaaa aggattactt gccaattata atatagtatt accaaacgct ttaaatggca
    16441 cgttcaatct taagaatgga acttacatag atattcttcc tgttttagtg atgtttttcg
    16501 tgacagggat tgtcctaatg aattcgaaat tagccctgag attcaatagt tttttagtta
    16561 ttttaaaatt ttcagcactg gctttattta tctttgtagg catttttttt attgatcaca
    16621 ataattggtc tcattttgct ccatatggtg taggacaaat tactggaggt aaaacaggta
    16681 tatttgctgg tgcttctgtt atgttctttg catttttagg atttgaatct atttcaatgg
    16741 cagttgatga agtgaaagaa ccacaaaaaa caatccctaa aggcatcatt ttatctttga
    16801 ttattgtaac agcactctat atagttgtca ccactatttt aacgggaatt gtacactaca
    16861 ctaaattaaa tgttccagac gcggtggctt ttgctttaag aaatattaga ctttattggg
    16921 cagctgacta tgtgtcgata gttgctattt tgactcttat tacggtatgt atttctatga
    16981 cctatgcatt agctagaaca atttacagta ttagtagaga tggtttatta cctaaatcac
    17041 tttatactct cactaaaaaa aataaagtgc ctcaaaatgc tactcttgtc actggactac
    17101 ttgctatgat ttgtgcggga atatttcctt tatcgagtct agcagagttt gttaatattt
    17161 gtactttagc atatttaatt attctgtcgg gtgcaattat taaactcaga agaatagaag
    17221 gagaaccaaa agcaaatgaa tttaaaactc ctctagtacc attcctacca atgttggcaa
    17281 ttatcatttg tctatcattt atgagccaat ataaagcttt tacttggatt gcttttgcta
    17341 ttgccacaat tattggaaca ttaatctact tagcttatgg ttatactcat tcaatagaaa
    17401 ataaataatg ttttgataat aagatttgac attacattat agactataat gtttagaagt
    17461 aaatgagcag taaaatcaat acctacttac ttatcaaagt tgtaatattt aaaattaccc
    17521 aacccctaga gaattgatta gtctctaggg gttgattggt acaatgacat agactctaaa
    17581 acgattttaa tactagatat atagatataa atttcaaaaa agaaaattag ttcatttttg
    17641 ttatacaata aaatttgtta tttagcagta atataattg
//
LOCUS       DAUCXI010000038        15142 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.038, whole genome shotgun sequence.
ACCESSION   DAUCXI010000038 DAUCXI010000000
VERSION     DAUCXI010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15142
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.038"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            50..538
                     /locus_tag="VGY43_001380"
     CDS             50..538
                     /locus_tag="VGY43_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEQ4302557.1"
                     /translation="MRTLKTGLSVFLVLLVFHLFGWKGLQIGALTAVFSLREDFDKSV
                     HFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLIVPICTMLCIMVNVACNNKTGI
                     IGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVAILVNTDVELIKNKWLNKKHSD
                     VR"
     gene            605..976
                     /locus_tag="VGY43_001381"
     CDS             605..976
                     /locus_tag="VGY43_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEQ4302558.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            1014..2360
                     /gene="glnA"
                     /locus_tag="VGY43_001382"
     CDS             1014..2360
                     /gene="glnA"
                     /locus_tag="VGY43_001382"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEQ4302559.1"
                     /translation="MAITVADIRHEVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDEADKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPVEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFVSQWEIDHYIHNY"
     gene            complement(2588..4270)
                     /locus_tag="VGY43_001383"
     CDS             complement(2588..4270)
                     /locus_tag="VGY43_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEQ4302560.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDILALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFNTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(4272..4502)
                     /locus_tag="VGY43_001384"
     CDS             complement(4272..4502)
                     /locus_tag="VGY43_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEQ4302561.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            4786..5484
                     /gene="tsaB"
                     /locus_tag="VGY43_001385"
     CDS             4786..5484
                     /gene="tsaB"
                     /locus_tag="VGY43_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEQ4302562.1"
                     /translation="MKTLAFDTSNKTLSLAILDDETLLADMTLNIQKNHSVSLMPAID
                     FLMTCTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHASLEVIIEQLVEEGQLIFVGE
                     TAPFAEQIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            5456..5911
                     /gene="rimI"
                     /locus_tag="VGY43_001386"
     CDS             5456..5911
                     /gene="rimI"
                     /locus_tag="VGY43_001386"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEQ4302563.1"
                     /translation="MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIR
                     RDQTDYFLLYDHDKLLGFLAIQDLAGEVEMTQIAILPSHQGLGLASQLMTHLDSIESD
                     IFLEVRESNHRAQGLYQKFGFKLIGKRPDYYRNPIETALLMKREGKHDR"
     gene            5901..6929
                     /gene="tsaD"
                     /locus_tag="VGY43_001387"
     CDS             5901..6929
                     /gene="tsaD"
                     /locus_tag="VGY43_001387"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEQ4302564.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYVPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(7100..7369)
                     /gene="rpsN"
                     /locus_tag="VGY43_001388"
     CDS             complement(7100..7369)
                     /gene="rpsN"
                     /locus_tag="VGY43_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEQ4302565.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(7604..8347)
                     /locus_tag="VGY43_001389"
     CDS             complement(7604..8347)
                     /locus_tag="VGY43_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEQ4302566.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSCIPIEIISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSC"
     gene            8587..9366
                     /gene="udp"
                     /locus_tag="VGY43_001390"
     CDS             8587..9366
                     /gene="udp"
                     /locus_tag="VGY43_001390"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HEQ4302567.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            9387..10589
                     /locus_tag="VGY43_001391"
     CDS             9387..10589
                     /locus_tag="VGY43_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEQ4302568.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRGTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            10619..11290
                     /gene="deoC"
                     /locus_tag="VGY43_001392"
     CDS             10619..11290
                     /gene="deoC"
                     /locus_tag="VGY43_001392"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEQ4302569.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIKNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEAT
                     KPDSY"
     gene            complement(11385..12554)
                     /locus_tag="VGY43_001393"
     CDS             complement(11385..12554)
                     /locus_tag="VGY43_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEQ4302570.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYSYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDVLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGQVLTSTEVVSVKKQDDLFYLKSADQTFTCQKLIV
                     TTGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLTAYLSDQRDKN
                     IKNALKGLLPERVTDFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
     gene            12815..13153
                     /locus_tag="VGY43_001394"
     CDS             12815..13153
                     /locus_tag="VGY43_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302571.1"
                     /translation="MKKRFNSKAITLLAVSSLSLGFTAVTSVVSAATAHPAPSPIIDE
                     WNYGVSDNYGYSNYYVKSPNNIGSKSSITNYWGSIKASDSQKYGWALSSSKKAWNDIR
                     LNAHWNYFNF"
     gene            13221..>15142
                     /locus_tag="VGY43_001395"
     CDS             13221..>15142
                     /locus_tag="VGY43_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302572.1"
                     /translation="MKLKLSVIGLFFCLIAAIGVISISDTQKPVPLPIDGAFSIQGKS
                     SLSSDEVYKKISNLSKTKNVNIYKPIVRNSGQLTYINFKNTNYEQLKSAPITGMYYTL
                     GKIDSSSLKVLTASGLKLVYAAYPWYIGGILQFDGTLRLLLMLSIYLTLLVVLFVVRT
                     RQIKEGVIRHSLGLPIYNLRRDYVISFTFELVMAGLLMIAYSYFWGSGLFTYSSKLFF
                     SLILTNLIIFQIVDIITFILFWLTIRVEKPIEIIKNKAKNSFLFIVWLVIISIIIIVS
                     GIFLQETKASQSRINRQISQLSPWNKVRNWKRLELLGIENGSINNGEINEPESQYIQI
                     ATALKKLDFIYIKPSSVYIPDYMKNTNFAEDFFKKLNNDGITDPEVNKEMIYINKSGA
                     NIQNKVNGTDYQLLDNKVATIYIPDKFKEKKKSIENTVVAEQFTGTKYTKENLAVQII
                     PNEKKIFYFNENGNEHDENKEASPMANVTDSKGNIVVVLDTDKMVASKDFSLASNIVN
                     SSLFSPEAIKKINDLSLHLNFSINPVDVYQLVKLNIQSLKHQIFLSKVLQKIIYGIVF
                     LLIYQYAQLFISSKQNDYVKKIILGLSKTRIAISSLKYFIMTIAIVIICTFMVTEQIE
                     LLYIGIASLVVLILSTV"
BASE COUNT         4742 a         2474 c         3042 g         4884 t
ORIGIN      
        1 aaaattatta tctaattaca agtttgatat taaaaagttt aaattgggaa tgagaacatt
       61 gaaaacaggc ttatcggtct ttttagtttt attggttttt catttatttg gttggaaagg
      121 gctccaaatt ggtgctctaa ctgctgtatt tagtttaaga gaagactttg ataaaagcgt
      181 gcactttggc ttttctagaa ttattggtaa tagtataggt ggcctactct ccttagtatt
      241 ttttgcattc aatgagatat ttcatcaagc tttttgggtt actttattaa ttgttcctat
      301 ttgtaccatg ttatgtatca tggttaatgt tgcatgtaat aataaaacag gtattattgg
      361 ggcagtggct gctcttttga ttattacact gtctattcca acaggacaaa cgtttattta
      421 tgtgacttcg cgggtatttg aaacattttg tggcgtcttt gtagctattt tagttaatac
      481 tgatgttgaa cttattaaaa ataaatggct taacaaaaaa cacagtgatg ttagataata
      541 taacatatat acttgacagg ttattttttt cagcctataa taaggaagat gaaaggagtt
      601 tgtcatgaaa gaaaaagaac ttagacgctc aatggctgtt tttcctattg gaacggtgat
      661 gacattaaca gatctctctg cgagacaaat tcgctattat gaagatcaag gtttaattaa
      721 gcctgaacga acgcaaggga atcggcgtat gttttcctta aatgacatgg accgactttt
      781 ggaaattaaa gattttttgt ctgagggatt aaatattgca gctattaaac gcgaatatgt
      841 cgagcgtcaa ggtaagttaa tgcaaaaaca aaaagctcta acagatgcag atgtcagacg
      901 gatcttacat gatgaaatgc tgacacaaag cggtttttct actccctcac agcatattgg
      961 taattttcgt atttaagata tgaattgtat aaaatttaaa ggagacctat ttaatggcaa
     1021 tcacagtagc tgacattcgt catgaagtca aagaaaaaaa tgtaacgttt cttcgcttga
     1081 tgttcactga tatcatgggc gttatgaaaa atgtggagat tcctgcaacg aaagaacagt
     1141 tagacaaagt attgtctaat aaggttatgt ttgatggttc atctatcgaa ggttttgtac
     1201 ggatcaatga gtcagatatg tacctttacc ccgatttaga cacttggatt gtttttccct
     1261 ggggagatga aaatggagca gttgcaggtt taatttgtga tatttataca gcagaaggaa
     1321 agccttttgc aggagatcct agaggaaatt taaaaagagc cctgaaacac atgaacgaga
     1381 tcggctacaa atcatttaat cttggaccag aaccagaatt tttccttttt aagatggatg
     1441 ataaaggtaa tccgacactt gaagttaacg ataatggtgg ttattttgat ttagcgccaa
     1501 ttgacttagc agacaacacg cgccgtgaaa ttgtgaatat tttaacgaag atgggttttg
     1561 aagtggaagc tagtcatcat gaagtggctg ttggtcaaca tgagattgat tttaaatatg
     1621 cagatgtttt gaaagcttgt gataatattc aaatttttaa gctagttgta aaaacgattg
     1681 cccgtgaaca tggactttat gctactttca tggctaaacc aaaatttgga atagctggat
     1741 cagggatgca ctgtaacatg tctttgtttg ataaccaagg taataatgct ttttatgatg
     1801 aagctgataa gcgaggaatg cagttatcag aagatgctta ttatttcttg ggaggactaa
     1861 tgaagcatgc ttataactac actgctatca ctaaccctac agtgaattct tataaacgat
     1921 tagttccagg ttatgaggca cctgtttatg tcgcttgggc tggaagtaat cgttcaccgc
     1981 ttatccgtgt tccagcatca cgtggtatgg gaacgcgttt ggagttacgt tcggttgatc
     2041 cgacagctaa tccttattta gccttggctg ttctcttgga agctggatta gatggtatca
     2101 ttaacaaaat tgaagctcca gaacccgttg aagctaacat ttataccatg acaatggaag
     2161 aacgaaatga agcaggcatt attgatttgc catcaacgct tcataatgcc ttaaaagctc
     2221 ttcaaaaaga tgatgtggta caaaaggcac taggttacca tatctacact aatttcttag
     2281 aagcaaaacg aattgaatgg tcttcctatg caacttttgt ttctcaatgg gaaattgacc
     2341 attatattca taactattag acttatcagg acctgctcaa gttgagtggg tcttttggat
     2401 gagctattgt atttgagcta gcaagctatt attagctgat cggacaccaa ttgattttcc
     2461 attatagaaa actaaaaacc agtccatgtt ctatgaggac tggtttttag tttgataatt
     2521 atctgaacta gaactgatat attaaagata tagacggata gtattaagaa atgagtctta
     2581 tttgatttta gtgcttatca ggtgttaaga ccatcggaat tataattggt tcacgctcag
     2641 tcttttcata caagaatgga cgaagagcat tgacgatagc accgttaact gattggatgc
     2701 tagcatcctt attttttaaa gcaatacgga tagcgttaaa gagcacacgt tggctttcgc
     2761 ggatcaagtc acctgactca cgcatataaa tgaaaccacg gctcagaata tctggtccag
     2821 ctaaaatcat ttgtgtgtta aaatcaacag ttgcaacagc taagacaaca ccatcttctg
     2881 acaaatcacg gcggtcccgt aaaacggctg ctccaatatc cccgatgcca ttaccatcca
     2941 cgtagatgtc ttgggcatta aagtgaccag caatacgcgc actgtcactg gttaaagcta
     3001 gaatgtctcc attttccata ataaagatat tttcttttgg aataccaata tccatcgcca
     3061 gtcctgcatg aactttttgc atgcgatact caccatgtac tggcatgaaa tattttggtt
     3121 taatcaaact aagcatgagc ttttgttctt gctgtcctcc atgaccagaa gtatgaatat
     3181 tattgacttt tccatgaata acatcaacac cagcttcttg gatggtattg attaatttat
     3241 tgacacttgt ggtattacca gggattggac ttgatgagaa aatcacagta tcaccaggct
     3301 gtaaagttac ttgacgatga gtgccattag cgatacgagc aagtgctgcc atagactcac
     3361 cttgactacc tgtacacata attaaaactt cactagcatg aagattttta agttcgcttg
     3421 gctcaatgaa ggtacctttt ggaactttaa tatagccaag ttcaataccg ttaacaattg
     3481 ccttttccat agaacgacca aaaacggcaa ttttacgtcc cgttttaaca gcagcttctg
     3541 cagcctgttg caaacggtag atgtttgaag cgaaggaagc aaaaataata cgcccatgaa
     3601 taccttcgat aatttttaaa atggattggc caacaacttt ttcagagtta gtaaaggttg
     3661 ggatttcagc attagttgag tctgataata agcaaaggac accttcttca ccaagcgctg
     3721 ccatacgttg taaatctgca ggatctccta ctggcgtaaa gtcaaattta aaatcaccag
     3781 tacagataat cttaccttga ggggtgtgga taacaatacc gaccggttct ggaatggaat
     3841 gagtagtctt gaagaaagtg acgctcatgt ttttaaaagt taactcggtg ttgtgattga
     3901 tttcgtaaac agttgcttca cgccaaagac catgttcttc caatttacca cggataagag
     3961 caagtgctaa aggtcctgcg tagataggga tattagcctg tttgagaaga aatggaatac
     4021 caccaatgtg gtcttcgtga ccatgtgtaa taacaagagc tttgacccgg tctaagttat
     4081 cgacaatgta agaatagtct ggaataacgt aatcaattcc caaaagatca tcttctggga
     4141 atttgatacc ggcatcaacg ataatgatct cgtcttgata ctcaatacca taagtattct
     4201 tcccaatctc tcccagacca ccaatggcaa acaccccaac ttcattaggt tttaaactga
     4261 tatttgtcat cttagaactc cgttaattca aaaacaccgg tctctttttc gtaatcgagg
     4321 tgtttgtcag aaagtagctc gataaattcc acgttataat aggtgttatc ttcaacgaga
     4381 cgacgagcct tgatacggcc atcgagttca tcagtagcat caatattaag atagagtgct
     4441 ttagtacttt cacgacgtgg gctttgatcc tttgtttctt gatagaaaac tttataaatc
     4501 atttgttttt tattcctttc gttatgaatc aattatccaa acaataataa ataggtcaaa
     4561 aggtaggtgt tccattttga cggttttata tgttgtcatt attgtgtagt agattaattc
     4621 ctgattctgt gcaattatta taattatacc ataaacttag cttttagtaa aaaatttagg
     4681 tacatttatg gtatagtcta aatcaaatta agagtcagcc tttttgttta tgattcttaa
     4741 tttgtgttat aattgatact agaacttgca gtagaaaggc ataaaatgaa gacacttgca
     4801 tttgatacct caaataaaac cttgtccctt gctatacttg atgatgagac acttctagca
     4861 gatatgaccc ttaacattca gaaaaatcat agcgttagcc ttatgcctgc tattgatttt
     4921 ttgatgactt gtactgatct taaacctcaa gatttagaaa gaatagtggt tgcaaaaggc
     4981 cctggatctt acacaggttt acgagtggca gttgctactg caaaaacgtt agcgtacagt
     5041 ttaaatattg cattggtcgg gatttcgagt ctatatgctt tggctgcgtc tacttgtaaa
     5101 cagtatccaa atactttggt ggtgccattg attgatgcta gaaggcaaaa tgcgtatgta
     5161 ggttattatc ggcaaggaaa atcagtgatg ccacaagccc atgcttcact agaagttatt
     5221 atagaacaat tagtagaaga aggacagctg atttttgttg gggagactgc tccttttgct
     5281 gagcaaattc aaaagaaact acctcaggcg atactacttc caacccttcc ttctgcttac
     5341 gaatgtggtc ttttggggca aagtttggca ccagaaaatg tagacgcctt tgtccctcaa
     5401 tatctcaaga gagtggaagc tgaagaaaac tggctcaaag ataatgagat aaaagatgat
     5461 agtcactacg ttaagcgaat ctaatatgaa aacagttgaa gaacaagcaa aaaatattta
     5521 tcagcttttg gaaatggttt atggcacgtc tccttggact ttagaacaag tattaatcga
     5581 tatacggcgg gatcaaacag attatttcct actatatgat catgataaat tgctaggttt
     5641 tttagctatt caagatttag ctggtgaagt tgaaatgact caaattgcta tactacctag
     5701 tcatcaagga cttgggctag cgtctcaatt gatgacgcat ttagatagca ttgaaagtga
     5761 catcttttta gaggttagag aatctaatca tagagcacag ggtttatatc agaagtttgg
     5821 ttttaaactt attggcaaaa gaccagacta ctatagaaat cctatagaaa cagctttatt
     5881 gatgaaacgg gaaggaaaac atgacagata ggtatatttt agcagttgag agttcttgtg
     5941 atgagaccag tgtagcgatt ttaaaaaacg aaagtaccct cttaagtaat gtcattgcaa
     6001 gtcaggttga gagccacaaa cgctttggtg gtgtggtgcc agaagtagct agtagacacc
     6061 atgtcgaagt gattacgact tgctttgagg atgctttgca agaagctggc atcagtgctt
     6121 cagatttatc agcagttgcg gtaacttatg gccctggact tgttggagcc ttgttagttg
     6181 gattagcagc tgcgaaggct tttgcttggg caaatcattt acctttgatt ccggttaatc
     6241 atatggcagg ccacttaatg gcagcgcgtg aacaaaagcc tttagtttat cctttaatag
     6301 cactattggt ttcaggagga cacacagaat tggtttatgt cccagagcca ggggattatc
     6361 atattattgg cgagacgcgt gacgacgctg ttggtgaggc ttatgataaa gttgggcgtg
     6421 tgatgggctt aacctatccg gcaggacgtg aaattgacca gttggctcat aaaggtcaag
     6481 atacttatca tttccctcgt gctatgataa cagaagacca cttagaattt tccttttcag
     6541 gactcaagtc cgcttttatc aatcttcatc ataatgctaa gcaaaaaggc gatgaactga
     6601 ttctagaaga tttgtgtgca tcttttcaag cagctgttct agatatttta ttggccaaaa
     6661 caaaaaaagc tctgagcaga taccctgcaa agatgcttgt agtggctggt ggtgtagcgg
     6721 caaatcaagg attacgagat agattagcac aagaaattac acatatagaa gttgtgattc
     6781 ctaaactaag actctgtgga gataacgcgg gtatgattgc tttagcagca gctattgagt
     6841 atgacaaaca gcattttgct aatatgagcc taaacgcgaa gcctagttta gcttttgacc
     6901 agtttccaga cagttttgta ataaactagt cacacttgct agttagtaag atttataatg
     6961 gataagaatc tccctttgaa aaaacaaccc ggtatcttgg cataccgggt tgtcatgatg
     7021 ataagtaatt ggcttctatg gttactaata attcagataa ttacctgcaa aataattgtc
     7081 tgcctaaggt gaagtaagct taccagctag ctttagtgac gccaggaagc tgtcctttgt
     7141 gagctaagtc acggaaattg atacggctaa caccaaactt acgcatgtaa gcatgaggac
     7201 ggccgtcaat tttgtcgcgg ttcttcaagc ggtttggatt tgaatcacga ggcaatttgc
     7261 gcagtgattc ataatcgccc ttcgctttta agtcacgacg aaggtcagcg tactgttcaa
     7321 tcagttggag ctgcttttgg tatttagcaa tttttgactt ttttgccatt gctttctcct
     7381 tcttaatatt taataacctc agagtcgtta tcagcgctct gaatccactt aactggtatt
     7441 taactggtta atcggatata taatcattat acaataaata aaagcaaaag caactaaaaa
     7501 aaattaacta gttatttttt tagccataat atcaaaaaac tccacatcta agtgtgggag
     7561 tcaggtatta ataactgttt aaaggtgttt aatgagtgtc gctttagcaa ctttgagatt
     7621 gaacttttaa gtcaaataaa tcagcaggaa cgtagtgttt ggttgagacc aagatgtctt
     7681 taccattgta gagagtttct tggattaaaa taaaagcact attttctgat agagtatact
     7741 tagttgctgt gtaattgcca gtcttggtat agccgatttg gttgcaggaa tgagaagctt
     7801 taccagattc atagattttc tcttctaaga aagtaagaag gggctcttct tgattgagat
     7861 ttatagcata tttagaaata atctcaatag ggatacaaga taaactataa gcaatagctt
     7921 tattttggct atgataccag cgatcaacaa taatcacaac aggagtttct tgttttaggg
     7981 atgctgtaat ggcaacagtg ggcacttcaa tccgatattc caactcaacc tttgtgatgt
     8041 cagatgatag gcttgcatat atggggtgtt gaagatattc gaaaccttgg tgatatttag
     8101 tttcaggagt cttgagtata aaatttccct ttcctctgat attttttatg agatgatcct
     8161 cttggaggag ggctagggat ttacgtagtg tcatccgact gacattgagc tgtctagcaa
     8221 gttcaggttc tgatggcagt tgcatgccag gactatatgt accatcttga ataagttgaa
     8281 aaatagtatt atatacttgc acatgtttaa gttttttgag ttttttggtt aagtcgttag
     8341 tagacatatc acttacctca ttaataatct ttagtggagt ttaacttgtc taaaaactat
     8401 tttagcacta acagtattcc ttgattagaa ttgtacccat ctatagtgtt agtatctcac
     8461 actcaggtac tttttgtcaa aaaagagatg aaaaacacct taaaaaagcg tttacaaaat
     8521 agagtgtgtg tgatactata caagtgtatc aaaaattaga caagtaaaat acaggaggtt
     8581 tttaacatgc aaaattattc aggtgaagtc ggattgcaat atcacctaca gattcgtcca
     8641 ggtgatgtag gtcgttatgt tatcatgcca ggtgatccaa aacgttgtgc aaaaattgca
     8701 gaacattttg ataatgcagt tcttgtagca gacagccgtg aatatgttac gtatacaggt
     8761 acattaaacg gtgaaaaagt tagtgttact tcaactggta ttggtggtcc atcagcgtct
     8821 attgcgatgg aagaattgaa actttgtggc gctgatacct ttatccgtgt tggaacatgt
     8881 ggtggtattg accttgatgt taaaggcgga gacattgtta ttgcaactgg agctatccgt
     8941 atggaaggta ccagtaaaga atatgctccg attgaatttc ctgctgtagc tgacttggaa
     9001 gtgacaaatg ctctagttaa tgcagctaaa aagcttggtt atacaagtca cgcaggagta
     9061 gttcaatgta aagatgcatt ttacgggcaa catgagccag aacgtatgcc agttagttat
     9121 gaattattaa ataaatggga agcatggaaa cgtctgggaa caaaagcgtc tgaaatggaa
     9181 tctgcagctc tttttgtagc agcaagtcat ctaggagttc gttgtggatc agatttcctt
     9241 gttgttggta atcaagaacg caacgctttg ggtatggata acccaatggc tcatgataca
     9301 gaagcagcta ttcaagttgc tgttgaagca ctccgcacac ttattgaaaa tgataaatca
     9361 caataagcga ggttttggaa gtcatcatgc aatttattta tagtattatt ggtattttat
     9421 tggtattagg aattgtgtat gcaatttctt tcaatcgtaa gagtgtttct ctaagtttaa
     9481 ttggaaaagc tcttatcgtt caattcatta ttgcgctaat cttagtacgt atcccactag
     9541 gccaacaaat tgttagtgtt gtttcaactg gagttactag cgtaatcaac tgtggtcaag
     9601 ctggtttaaa ttttgtgttt gggtcattag cagatagtgg cgcaaaaact ggttttattt
     9661 tcgctattca aacgcttggt aatattgttt tcttatctgc cctagttagt ctactttatt
     9721 atgtaggaat ccttggattt gtagtaaaat ggataggtaa gggcgttggt aaaattatga
     9781 aatcctcaga ggttgagagt tttgttgccg tagctaatat gtttcttggt caaacagaca
     9841 gtccaatttt ggttagcaaa tacctaggtc gtatgactga tagtgagata atggttgtgt
     9901 tggtatcagg tatgggaagt atgtcagttt ctattcttgg tggctatatt gcattaggca
     9961 ttccaatgga atatctcttg attgcttcaa caatggttcc tattggcagt attctcattg
    10021 ctaaaatctt attgcctcaa acagaacctg ttcaaaaaat tgatgacatt aagatggata
    10081 ataaaggtaa taacgccaat gtgattgatg caatcgctga gggtgcaagc acaggtgcac
    10141 aaatggcttt ctcaattggt gctagtttga ttgcctttgt tggtttagtt tctttgatta
    10201 atatgatgtt aagtggattg ggaattcgct tagaacaaat cttctcatat gtttttgctc
    10261 catttggttt tcttatggga tttgaccaca aaaacattct tctagaagga aaccttcttg
    10321 gaagtaagtt gattttaaat gagtttgttt cgttccaaca attgggtcac ctaatcaaat
    10381 ctttagatta tcgtacagca ttggtagcaa ctatttcact ctgtggtttt gctaatttat
    10441 caagtttagg tatttgtgtt tcaggtattg ctgttctttg cccggagaaa cgtggcaccc
    10501 tagctcgact tgttttccgt gcaatgattg gcggtattgc tgtaagtatg cttagcgcct
    10561 ttatcgtcgg tattgtaact ctattctaaa cgttgacaaa agaaagaagg atagtaacgt
    10621 ggaagtaaaa gatattttaa aaacggtaga ccatactttg ctagcaacaa cagcaacgtg
    10681 gccagaaatc caaacaattt tagatgatgc catggcttat gaaacagctt cagcatgtat
    10741 tccagcctct tacgtcaaaa aagcagcaga atacgtttca ggtaaattag ctatttgtac
    10801 tgttattggg ttcccaaatg gctatagtac aactgcagcg aaggtttttg aatgtcaaga
    10861 tgctattaaa aatggtgctg atgaaattga catggtcatt aatttgacag acgttaaaaa
    10921 tggggatttt gatactgttg aagaagaaat tcgtcaaatc aaagccgcat gtcaagacca
    10981 tatcttaaaa gttatcgttg agacatgtca attaactaaa gaagaactta tcgaactttg
    11041 tggagttgtc acacgttcag gtgcagactt tattaaaacc tctactggtt tttcgacagc
    11101 aggtgctaca tttgaagatg ttgaagtgat ggcaaaatat gtcggcgaag gtgttaaaat
    11161 taaggcagca ggtggaatct catcattgga agatgctaaa acatttattg ctttaggagc
    11221 ttcacgcttg ggtactagcc gtatcatcaa gattgttaag aacgaagcta caaaacccga
    11281 tagctattaa cttaatcata ccgatttagc ttgagactaa aacaaaaaac tcatgtaata
    11341 ggagttaaaa agcctactat cttagtgata ataggctttt ttagctatga agacttccct
    11401 gcgatccatc ctgaacaaag agctgaggta atattaaacc ctccggtgtg agcattaata
    11461 tctaagacct ctccagcgaa atacaggcca ggaactttct tgctttccaa ggttttaggg
    11521 ttgatttctt ttaaatctac gcctcctttg gtcacaaacg atttagccaa agacattttt
    11581 cctgtaatgg gtatctggag gtgtttgagt ttatcaagca attccttttc ttgttttgga
    11641 gagagttgtt tgaccttttc ggggtaatct tctgataaaa aatcagttac tcgttcaggc
    11701 agtaggcctt taagagcatt tttgatgttt ttatcacgtt gatcactcag ataagcggtt
    11761 aagtcatctg ttgataagtg tggcaaaaag tccagctctg caatttctcc acctttcaca
    11821 aaagaggaca gacgaagagc tgcaggtcct gaaaggccaa agtgggtgaa gagtaagtcg
    11881 tgtgtgatga cgtgtttgtc ataactaaga gtaacgtcgt ctagggaaat accttgcaag
    11941 actttgtgag gaaaatcagt taacagaggg ctctcagcag cttctaaatc agtcacggtc
    12001 agtttaaaat gccgtgcaat atcatgtcca aaacctgttg aacccgttga agggtaggac
    12061 ttgcctcctg tggtcacaat caatttttgg caggtgaaag tctggtctgc agatttgagg
    12121 tagaagaggt catcttgttt tttaacggaa accacttcag tgctggttag cacctgaccc
    12181 ccaagagcct tgattttttt ctccagagca tcaatgattg tccttgattt atctgttgtg
    12241 gggaacatcc gtccatggtc ttcttctttg agtttgacgc cgttttcctc gaaaaaggca
    12301 atgatgtcat ggttgtcaaa ctgggaaaaa acactatata aaaagcggcc atttccagga
    12361 atgccagcca taaggacatc aaggttacca ctattagtga cattacagcg tccaccaccg
    12421 gttcccgcta attttttacc taagcggcga tttttttcaa ttaagagagt tttatagcta
    12481 tagtagctgc tggagatggc ggccatcata ccagcagggc cacctccaat aataatcgta
    12541 tcgtattgag tcatagcctt attttagcat aaaagcgggg gatttaatag tcaggtaaat
    12601 gaactaacat ggcataccgt tttttacgca tttaaacaat gcctccatga catcaaaaag
    12661 ctcgaaaaat agtccagatg attaaaatta tctttgtatg aaaacggttg cttttttatt
    12721 taattcatgc tattatatta ctaaagaatg aagtaatcat taagttcttt tgtaattttt
    12781 taaaaattaa ataattttat taaaggagaa tagtatgaaa aaaagattta atagcaaagc
    12841 gataactttg cttgctgtaa gctctttaag tttgggattt acggccgtaa ctagtgttgt
    12901 cagtgcggca acagcacatc cagctccatc tccaattatt gatgaatgga attatggagt
    12961 aagtgacaac tatggttatt ctaattatta tgttaaatct ccaaacaata ttggttcaaa
    13021 atcttcgata actaattatt ggggatccat taaggcatct gattctcaaa aatacgggtg
    13081 ggcactgtca agttcaaaaa aagcttggaa tgatattcgg ttgaatgcac attggaatta
    13141 ctttaatttt tagaaatggt atatgcaagc taaaggccca ataattatta tagggtcttt
    13201 tataatatag gaagttgttt atgaaattaa aattatctgt cattggatta ttcttttgct
    13261 taattgctgc gataggtgtt atcagtatta gtgatactca aaaaccggta cctttaccaa
    13321 ttgatggtgc cttttcaatc caaggaaaaa gtagcctttc tagtgacgaa gtttacaaaa
    13381 agattagtaa tctatcaaaa acgaaaaacg ttaatattta caagcctata gttcgtaact
    13441 caggtcagtt gacttatatc aattttaaaa atacaaatta tgaacaatta aaatctgcac
    13501 cgataacagg catgtattat accttaggta aaatagattc aagtagctta aaggtactta
    13561 cagcttcagg tttgaaactt gtttatgcag cgtatccttg gtatataggg gggattttac
    13621 aatttgatgg gactttaagg ttgttattga tgctatcaat ttacttaaca ttattagttg
    13681 ttttatttgt tgttagaacg aggcagatta aagaaggagt gataagacat tctttaggat
    13741 tgcctatata taacttaaga agagattatg tcatttcttt tacttttgaa ttggttatgg
    13801 ctggtttatt aatgattgcc tacagctatt tttggggaag tggcctcttt acttacagtt
    13861 ctaagttatt tttctctcta attttaacta atcttataat attccagatt gttgacatta
    13921 tcacttttat tttattttgg ctaactatta gggttgagaa acctattgaa attataaaaa
    13981 ataaagcaaa aaatagtttt ctttttattg tatggcttgt aattatttct attataataa
    14041 tcgtctcagg aatcttttta caagaaacaa aggctagtca atcaaggata aatagacaga
    14101 taagtcaact atccccatgg aacaaagtaa gaaactggaa aagactagag ttgttgggga
    14161 ttgaaaatgg ctctatcaat aatggggaaa taaatgagcc agaatcacaa tatatacaga
    14221 tagcgacagc cttaaaaaaa ttagatttta tatatatcaa accctcttca gtatatattc
    14281 cagattacat gaaaaatact aactttgcag aagatttttt caaaaaatta aataatgatg
    14341 gtataacgga tccagaagta aataaagaga tgatttatat caataaatcg ggcgctaata
    14401 ttcaaaataa agtcaatgga acagactatc agctgttaga taataaggta gcaacaatct
    14461 atattcctga taaatttaaa gagaaaaaga aatcaattga aaataccgtt gtggcagagc
    14521 aatttactgg aactaagtat acaaaagaaa accttgcagt gcagataatt cctaatgaga
    14581 aaaaaatttt ttattttaat gagaatggaa acgagcatga tgaaaataaa gaagcctcac
    14641 ctatggcaaa tgtaacagat agtaaaggta atatagtcgt tgtgttagat actgataaaa
    14701 tggtagcaag caaagatttt tctttggcta gcaatatagt aaatagctct ctttttagtc
    14761 ctgaagcaat aaaaaaaatt aatgacctga gtctacattt aaatttttca attaatccag
    14821 tagatgttta ccaacttgta aaacttaata ttcaatcctt aaagcaccaa attttccttt
    14881 cgaaagtttt gcagaaaatt atttacggca ttgtatttct actaatttat caatatgctc
    14941 aattatttat ttcttcaaaa cagaatgact atgtgaaaaa aataatttta ggcctctcaa
    15001 aaacacgcat agcaatttcg agtctcaaat attttattat gactattgca atagttataa
    15061 tatgtacatt tatggtgaca gagcagattg agttattata tattggtatt gcttcattag
    15121 tggttttaat tctttcgaca gt
//
LOCUS       DAUCXI010000039        14917 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.039, whole genome shotgun sequence.
ACCESSION   DAUCXI010000039 DAUCXI010000000
VERSION     DAUCXI010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14917
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.039"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            104..841
                     /locus_tag="VGY43_001396"
     CDS             104..841
                     /locus_tag="VGY43_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ4302573.1"
                     /translation="MGKEIKVKYFLRRSAFGLVAVSASVLVGSTVSAVDSPIEQPRII
                     PNGGTLTNLLGNAPEKLALRNEERDIDELKKQAIEDKEATTAIEAASSDALEALADQA
                     DTLQSEEAAAVQSDNAASDALEALADQADALQSEEAAVVKADNAASDALEALADQADA
                     LQSEEAEVVQSDNAASDAWEKAATPIALDVKKTKDTKPVVKKEERQNVNTLPTTGEES
                     NPFFTAAALAIMVSTGVLVVSSKCKEN"
     gene            1079..1621
                     /locus_tag="VGY43_001397"
     CDS             1079..1621
                     /locus_tag="VGY43_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEQ4302574.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            1630..2913
                     /locus_tag="VGY43_001398"
     CDS             1630..2913
                     /locus_tag="VGY43_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEQ4302575.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANNQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCENSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            2929..3789
                     /locus_tag="VGY43_001399"
     CDS             2929..3789
                     /locus_tag="VGY43_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEQ4302576.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            3791..4756
                     /locus_tag="VGY43_001400"
     CDS             3791..4756
                     /locus_tag="VGY43_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEQ4302577.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPASAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            4867..6150
                     /gene="aroA"
                     /locus_tag="VGY43_001401"
     CDS             4867..6150
                     /gene="aroA"
                     /locus_tag="VGY43_001401"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEQ4302578.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            6143..6634
                     /locus_tag="VGY43_001402"
     CDS             6143..6634
                     /locus_tag="VGY43_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEQ4302579.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIESQVLKDLLFTNDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EGY"
     gene            6842..8293
                     /locus_tag="VGY43_001403"
     CDS             6842..8293
                     /locus_tag="VGY43_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEQ4302580.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            8342..9733
                     /gene="rlmD"
                     /locus_tag="VGY43_001404"
     CDS             8342..9733
                     /gene="rlmD"
                     /locus_tag="VGY43_001404"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEQ4302581.1"
                     /translation="MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVD
                     NALPEEVIDMRVLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQ
                     LTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKH
                     SHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGE
                     MMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTI
                     TDSMLGNNYAISAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFA
                     KTVKAVYGVEVIEAAVRDAQHNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVD
                     PPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQT
                     HHVECVSLLEKRS"
     gene            9885..10666
                     /locus_tag="VGY43_001405"
                     /pseudo
     CDS             9885..10666
                     /locus_tag="VGY43_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            10751..11152
                     /locus_tag="VGY43_001406"
     CDS             10751..11152
                     /locus_tag="VGY43_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEQ4302582.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKTSLTMFVTGRRHNG"
     gene            complement(11257..12741)
                     /locus_tag="VGY43_001407"
     CDS             complement(11257..12741)
                     /locus_tag="VGY43_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEQ4302583.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            13115..14335
                     /locus_tag="VGY43_001408"
     CDS             13115..14335
                     /locus_tag="VGY43_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ4302584.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLSL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLCFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     SIGQLKAERYQQLR"
     gene            complement(14455..14820)
                     /locus_tag="VGY43_001409"
     CDS             complement(14455..14820)
                     /locus_tag="VGY43_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEQ4302585.1"
                     /translation="MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
BASE COUNT         4636 a         2581 c         3160 g         4540 t
ORIGIN      
        1 tatgcaatta atctgtataa taaaagatgg aattattaat tataatttcc aaattatcgg
       61 taatttaata tgctaatgca tataaaaata aaaaggagaa acaatgggaa aagaaataaa
      121 agtgaaatac tttttgcgta gatcagcttt tggattagtt gcggtgtcag catcagtatt
      181 agtcggttca acagtatctg ctgttgactc acctatcgaa cagcctcgaa ttattccaaa
      241 tggcggaacc ttaactaatc ttcttggcaa tgctccagaa aaactggcat tacgtaatga
      301 agaaagagac attgatgaat taaaaaaaca agctattgag gataaagaag ctacgacagc
      361 tatagaagca gcaagttcag atgccttaga agcattagcg gatcaagcag acactttaca
      421 atcagaagaa gctgcagcag ttcaatcaga taatgctgct agtgacgcct tagaagcatt
      481 ggcggatcaa gcagacgctt tacaatcaga agaagctgcg gttgttaaag cggataacgc
      541 tgctagtgac gccttagaag cattagcgga tcaagcagac gctttacaat cagaagaagc
      601 tgaagtagtt caatcagata acgctgctag tgacgcctgg gaaaaagcag caactccaat
      661 cgctttagat gttaagaaaa ctaaagatac aaaacctgta gttaaaaaag aagaaagaca
      721 aaacgttaat acccttccta caactggtga agagtctaac ccattcttta cagctgctgc
      781 gcttgcaata atggtaagta caggtgtgtt agttgtaagt tcaaagtgca aagaaaatta
      841 gttgctattt gttctagcaa atgaaacaag ggaatcgaaa gattctcttt ttctgatatt
      901 taaaaatgct acagtttata atagcttgaa agactaaatg ttctcaaact cattagaaca
      961 agctttaata aaactaaccc agttgtatca aaggatagat aaagactaag actgttatag
     1021 aatatttgca aaagatttgt tataatggac ccaatacagg tattgtgaaa ggtataatat
     1081 ggatatttgg acaaagcttg cagtgtttgc tttttttgag actccgaaag taatattacg
     1141 gccttttcgc tatgaagatc attgggattt ttacagcatg gttaacgaca ctaaaaacct
     1201 ttattatgtt tttccagaac aaaaaactaa ggcagcaagt gactatcttt tagtacatag
     1261 ttttataaag tttcctttag gtcagtgggc aatagaagat aaagcaaccc accaagtaat
     1321 aggttctatt agaattgagc attatgatgc taaaacgcgt tgtgctgata ttggctattt
     1381 tttaaactat gccttttggg gacaaggaat tatgacagaa gtcgtaataa aacttgttta
     1441 tttatctttt cacgaatttg gtctcaaaac gttgcgtatt ataactcatt tagaaaataa
     1501 ggccagccag aaagtagcta aaaaagcagg ttttcaacta aaaacctgtt ttaaaggaag
     1561 tgatcgtaat actcataaaa tctgcattta taaaatgtac caactaacta atgataggtg
     1621 ataatcatta tgagcaaaca tcaagatatt ttagattatt tagaaaaact tgctattggt
     1681 aaaaaagtga gtgttagaag catttcaaac cacttaaaag taagcgatgg aacagcctac
     1741 cgtgctatta aagaggcaga aaatcgaggt attgtcgaaa ccaaaccaag aagtggaact
     1801 gttcgtattg aaaaaaaagg acgggttcgt attgaccgtc tgacctattc cgaaattgct
     1861 cggatcagtg attcggaagt gctagcggga catgctggtt taggacatga atttagtagg
     1921 ttttcaattg gtgctatgac tcaacaaaat attcgtcgtt acttggtcaa aggagggtta
     1981 ttaatagttg gggatcgtga aacgattcaa ctcttagctc ttgaaaacca taatgccatt
     2041 ttggtgacgg gcggatttcc agtatccaaa cgtgttattg aaatggcaaa taaccaacga
     2101 atcccagtta tggtaactca ttatgatacc tttactgtgg caacaatgat taatcacgcg
     2161 ctatctaata ttcgtattaa aacagatctc aaaacagttg aacaggtaat gatacctatt
     2221 acagattatg gttacctttg cgaaaacagc tccgttgaag aattcaatac attaataaaa
     2281 aaaacacgac aagtcaggtt tcctgtatta gattataaaa gaaaagtgat tggtgtagtt
     2341 agtatgcgtg atgtggtgga tcagttgcca acaactaagc ttaccaaggt catgtctaaa
     2401 aatccaataa cggctagacc aaatactagt cttgctaata ttagccagaa aatgatcttt
     2461 gaagatttaa acatgttacc tgtcactgac gaagaaaaca atttacttgg tatgattact
     2521 cgtagacaag caatggaaaa tttgccaaat caccaaccaa ataaccccta tacttatagt
     2581 gagcaaatac tttctaacct tgaagaaacg gttgattatt accaagtagt agttgagcca
     2641 acaatgattg atagtgctgg taacatgtca aacggtgtta tttcagagtt cttaaaggaa
     2701 attagtatca gagccctcac gaaaaagcac caaaaaaata tcattatcga acaaatgatg
     2761 gtatactttt tacatgctat tcaaattgag gatgaattaa aaatatatcc taaaatcatt
     2821 actgaaaata gacgaagcag caccattgat attgaaattt ttgtggatga tcaagtgatt
     2881 gctaaagcta ttattacaac gaaaataaat tagaggagta acaaaacaat gataacatta
     2941 aaatcagccc gtgaaataga agcgatggat agagcaggag acttcttagc aggtatccat
     3001 attggcttaa gggatattat taagcctggt gtggatatgt gggaagtgga agcatatgtt
     3061 cgtcgccgtt gtaaagaaga caacgttctt cctttgcaaa taggggttga tggtcacatg
     3121 atggactatc cttatgcgac ctgttgtggt ctaaatgacg aagtagcaca tgcctttccc
     3181 cgtcattaca ttctgaaaga aggggatttg cttaaagttg acatggtact cagtgagcct
     3241 ttggataaat caattgttga tgtagcagct ttagattttg ataacgtgcc tgagatgaag
     3301 aaatggacag gatcttatac cggtggttta gctgactctt gttgggctta tgctgttgga
     3361 acaccgtctg acgaaataaa gcaattaatg gatgtcacca aagaagccat gtaccgtggt
     3421 attgaaaaag cagtaattgg caatcgtatt ggtgatattg gcgcagctgt tcaagaatac
     3481 gctgaaagct tcggttatgg tgtcgtgcgt gatcttgttg gtcacggtgt tggtcctaca
     3541 atgcatgaag agccaatggt accaaactat ggaacagcag gtcgtggact tcgtctaaaa
     3601 gaaggcatgg tcttgactgt tgagccaatg attaatacag gaacttggga aattgatacc
     3661 gacatcaaga caggttgggc tcataaaacc ctagatggtg gtttatcttg ccaatacgaa
     3721 caccaatttg tgattactaa agatggtccc gttattttaa caagtcaagg agaagaaaga
     3781 acttactaaa atggcagaaa aaaaatggtt tgataaggta ctgtccaagt ggcagtatga
     3841 acccattcaa gtctttatga ggcatttaca aagtgcagaa atggatttat ctgccattgc
     3901 ggttgcgtat taccttatct taacggcctt tccattaatt gttattgcag ccaatatttt
     3961 tccttacctc aatattgata ttgctgattt gttacgtcta atgaagcaaa atttgcctaa
     4021 agatattttt agaccggctt ctgcaattgt agaaaatatt ttctctaaac cgtctggaag
     4081 tgttttggga gtagcgactt tgacaggatt atggacaatg tctcgaagtt tgacatcgct
     4141 gcaaaaagct attaataaag cctatggcgc ttctcagcat cgagatttct ttatcggaca
     4201 cttggttggt ttgttgacca gtttaattat tttattttta ttagcctttg ccttaatctt
     4261 ttcaacattt tctaaagctg ctattcaagt gctggataag cattaccatt tgagtgataa
     4321 tatcacaacg attttcttac tcctcattca acccattaca gttttgatta tttttgttgg
     4381 cttgatgcta ctatattttt tattacccaa tgttaagatt aaaaaaattc gctacatttt
     4441 accaggaacc ctatttacat cttttgtgat gacatttttg agtaatctgg ttggcaatta
     4501 cgttgtgtat aatgttgagc ggatggtaga tattaaaatg tttggttcag ttatgatttt
     4561 tatcatcatg ctatggttta ttttcttagc aagaatcctg attttaggag ctatatttaa
     4621 tgcgacctat caagaaatgt ccttggggaa attagaaggt cgtagtggtg atatgatcgc
     4681 tatccttaaa aaaacacttg ggaatgattc agatctatct ccttcacagt ctatcgaaga
     4741 tagtcacact gattgataca aaaaagataa taagtcgtgg agtgagaaac tattttcttg
     4801 cttcattttt tatgaggatg aatagaaaat cattgatctt agcaaataga aaggcagatg
     4861 aaacggatga aattgcgaac aaatgcagga ccgttacagg gaacgattca agttccagga
     4921 gacaagtcca ttagtcaccg ggcagtcata ttaggagccg ttgctaaagg ggaaacacga
     4981 gtaaaaggac tcttaaaagg agaagatgtg ctttccacga ttcaagcctt taggaatttg
     5041 ggggtccgta tcgaagaaaa agatgaccag cttgtgatag aaggtcaagg ttttcaagga
     5101 ttgaccgctc cttgtcagac acttaatatg ggaaattctg gaacctctat gcgcctcatt
     5161 gctggtttat tggcaggtca accttttagt gtcaaaatga ttggcgatga aagcttatcc
     5221 aaacgtccta tggatcggat tgtttatccg ttaaagcaaa tgggggttga gatatctgga
     5281 gaaacagata ggcaatttcc tccactacaa ttgcaaggta atcgtaattt acaaccaatc
     5341 acatatactt tgcctatctc ttctgctcag gttaagtcag ctattttgtt agcagctttg
     5401 caagcaaaag gaacaacaca ggttgttgaa aaagagatta ctcgaaacca tacagaagaa
     5461 atgattcaac aatttggtgg acgattgata gttgatggta aacgcattac tttggtggga
     5521 ccccagcagc tcactgctca agagataact gtccccggag atatttctag tgcagctttt
     5581 tggcttgtcg ccggcttaat tattcctggt tcggagctcc ttttaaagaa tgttggagtc
     5641 aatccgacac gaacagggat tcttgaagtg gttgagaaaa tgggagcaca gattgtctat
     5701 gaagatatga ataagaaaga gcaagtaact agtattcgag tggtatattc tcacttgaaa
     5761 ggaactatca tatcaggagg tcttatccct cggttgattg atgaacttcc catcattgca
     5821 cttcttgcaa cccaagcaca aggaacaacc tgtattaaag atgctcaaga attacgagtc
     5881 aaagaaacag atcgtattca agtagtaact gatattctta acagtatggg agctaatatc
     5941 aaagcgacag cagatggcat gattatcaaa ggccctacgg tactatatgg ggctaacaca
     6001 agtacctatg gagatcatcg tattggtatg atgacagcaa ttgcagcctt gcttgttaaa
     6061 caaggacagg tccatttgga taaagaagaa gccatcatga cgtcttatcc gacgtttttc
     6121 aaagatttag aaaggctgtg tcatgactaa agtgttattg ggatttatgg gagtgggaaa
     6181 aacaacggtt tcgaaacacc taagtatgca ctgtaaagat atggatgcta ttattgaagc
     6241 taaaatcggt atgtctattg cagctttttt tgaacagcat ggagaaatag catttcgaac
     6301 aattgaaagt caagtgttaa aagatctatt gtttacaaat gataatagtg tcatcgtaac
     6361 aggtggcggt gtagtggttt tacaagaaaa tcgacaatta ctgagaaaaa atcaccagca
     6421 taatatttta ttggtagctt cttttgaaac tttgtaccag cgtttaaaac atgataaaaa
     6481 gtctcaaaga cctctatttc ttaagtactc taaggaagca ttttatgaat tttatcaaca
     6541 acgtatggta ttttatgagg gactttcaga tttagtaatc agagttgacc atcgtacgcc
     6601 tgaagaagtt gccaacatca ttgagggtta ttagcaggtc attgtcgtaa tctgatattt
     6661 atggttttaa acaggtatct gtctaaagta cttcttatgg caagttggct ttattaaata
     6721 ttaggaaata atcttgatta ttctataatg attaaaattt tgagaggaca atctggctaa
     6781 tataggttat aatggtagta ttcgttaaaa gtgcaattgt aatactaaga gatgataaga
     6841 tatgacaaaa taccccatgg gtggccttag tcaccatgaa gaattacgtt atttttatct
     6901 cctaaggaat ttgagttacc ttagtgagaa tgaaaaaaaa gagtttgctt ttttaaaatc
     6961 taaattggaa attggtcgag cttatgcgcc ttctaagcag cattatagga agtcaaaacg
     7021 gcaagaacct tactttgaag atgactacta taacgactac tcaccaaatg atttactaga
     7081 agatgatgac gtcaatcatg actcttcttt tgttccatat ggtttaccga tatatcctaa
     7141 agaagacaga tatttaaaca aaaaaacaaa acttacagct cgtagaccta tagatgctcc
     7201 gcagcctatt gatgaagacg atgctttttt aacagaatct gttgctcgtt gtgctcttcc
     7261 tagatctcaa aaaagaaagc ataagaaaaa aggatgtatg aaatggtttt ttaacattct
     7321 tggcttattg ctaatgactg tgcttatggg gttagggttg atgtttgcaa aaggggtttt
     7381 tgatatttct actaataaag ctaattacaa accagctgtt tcccaagctt ttgatggtca
     7441 agaaactcaa gatggtacga acattctggt tttgggttct gaccaacgag ttactcaagg
     7501 ttctacagat gctcgcacag ataccattat ggttgtcaat gtcggcaacc atgctaaaaa
     7561 aataaaaatg gtctctttta tgcgtgacac tttgattaac attccaggat acagttataa
     7621 tgataattcg tatgatctta aattaaatag tgcatttaat cttggagagc aagaagatca
     7681 ccacggagca gagtacgttc gacgggcctt aaaacataat tttgatatcg acattaagta
     7741 ttatgtgatg gtagattttg aaacatttgc agaagctatt gacaccttgt ttccaaatgg
     7801 tgttaagatt gatgccaaat ttgcgacagt aggtggtgta gctgttgact ccgtagaagt
     7861 tccagatgac ctgcgaatga aaaatggggt tgttcccaac caaaccatcg aagttggaga
     7921 acaacgcatg gatggtagaa ccttgctcaa ctatgctcgt ttccgtaaag atgacgaagg
     7981 agatttcgga cgaaccgtcc ggcagcaaca ggttatgtca gctgttatgt cccaaatcaa
     8041 ggacccaact aaactcttta cagggtctgc ggctattggt aaaatctatg cgctgacttc
     8101 gaccaatgtt tcttttccat ttgttgttaa aaatggtgtt tctgttttag gaagtgggaa
     8161 aaatggagtt gagcacgtga ccatcccaga aaatggggat tgggttgacg aatacgatat
     8221 gtatggagga caagctcttt acatagattt tgataagtat cagaaaacgt tagccaaatt
     8281 aggtttgcgc taagatatgg tataatggag agtaactaaa gttgctcttc ttttttgagc
     8341 aatggttagc cctagaaaag gaaaaagaat aagaatgttg aaaaaaaatg atattatcca
     8401 agttgctatt tcagatttaa gccatgaggg agcaggtgtc gctaaacacg atggttttgt
     8461 tttctttgtt gataatgcct tgccagaaga agtgattgac atgcgtgtct taaaggtcaa
     8521 taaaaacagc ggttttggca aagtagaagc ctatcattac ctgtcgccag ctagaaatgc
     8581 agatgtcaat ttaacttatt tgcgaacagg cattgcagac cttggacatc taacttatga
     8641 agaccaactg actttcaaaa agaaacaagt tcaggacagc ctctataaaa ttgctggaat
     8701 cagtgacgta acagtcgaaa gcacgattgg gatgacagaa cctttagctt accgaaataa
     8761 ggctcaagtt cctgttagac gtgttaatgg tcagctagaa acaggctttt tccgcaagca
     8821 ttctcatgac ttgattccta tttcggatta ttatattcag gacaaagaga ttgatcgtct
     8881 cattaatttt acccgtgatt tattacgccg ctttgatatt aaaccgtatg acgaaacaga
     8941 acaaacaggt ctcttgagaa atattgttgt tcgccgaggc cattactctg gagaaatgat
     9001 gctggtctta gtgactacac gcccaaaagt tttccgtgtt gaccaagtca ttgaaaaaat
     9061 cgttgaagct tttccagcag tggtgtctat tattcaaaat attaatgata agaataccaa
     9121 tgcaatcttt ggtaaagatt tcaaaacgct ttacggcaag gataccatta ctgatagcat
     9181 gcttggaaac aactatgcca tttctgccca gtctttctac caagtgaata cggttatggc
     9241 agaaaaactc tatcaaacag ctatagcctt ttcagacctt tctaaagatg acattgtgat
     9301 tgacgcctac tcaggtatcg gaaccattgg cctatcattt gctaaaacag ttaaagctgt
     9361 ttatggtgtt gaagtgattg aagcagctgt tagagatgct caacacaatg ccgctcttaa
     9421 tggcatcacc aatgcctact ttgtcgcaga taccgcagaa catgccatgg caacatgggc
     9481 gaaagatggc attaaaccaa gtgttattct ggtagacccg ccacgaaaag gcttaacaga
     9541 aagtttcatc caagccagcg tggcaatggg accacaaaaa attacctacg tttcctgcaa
     9601 cccagccacc atggcgcgtg acatcaagcg ttatcaagag ttgggttaca aactggccaa
     9661 agtacagccc gtagatttgt ttccccagac gcatcacgtg gagtgtgtaa gtttacttga
     9721 gaaacggagt taaagagtcc gcctcactct gttatttcaa ggtgagacgc tcaaaaggtc
     9781 cactggacct tttgactccc gcagacgcat cacgtcgagt gcgtagtgtt gctaatcaag
     9841 gagtaaggta gctgcctcca catgacaaaa ataaggagaa acgaatgcct attaccaaac
     9901 acgagattcc ccttttagaa tgtgatagta atccatcagc cgtcattata cctacacatg
     9961 aaggtctaca gctaagtgtg tctatgcttt cttagaagac gagattgaag cttttgcttt
    10021 agaccatcaa ggtaaaaaag tagcagaatt catttcagcc acaaaggttt accctgttta
    10081 tcagatacct tataaaggcc aagacatttg cctagctcaa gctcccgttg gctcagctcc
    10141 tgcggcgcaa ttcatggact ggctgattgg ttatggggtt aaagaaatga tcagtacagg
    10201 aacctgtggc gttttggttt ctatcgcaga aaaccgtttt ttagtgccag ttaaggcttt
    10261 gcgagatgaa ggaacaagtt atcattacgt ggcaccatct cgttatattg atattgatcc
    10321 taagatgctt agactgattg agaaaacgct tttagcacag gggttagctt atcaagaggt
    10381 catcacctgg tcaacagatg gtttttaccg agaaaccaaa gaaaaagtgg cttatcgcca
    10441 ggaagaaggg tgttcggttg ttgagatgga atgttctgcc ttagcagcag tagctcaatt
    10501 aagaggcatc ctttgggggc aactcttatt tacagcagat actctagcag atgtagaggt
    10561 ttacgatcaa cgcaactggg gtgctgattc ctttagtttt gcgcttcatt tatgcttgga
    10621 agtgctcaat acgctagaaa aggatggaaa ggctactgat ttttgaaaca tgagctctgc
    10681 cttctgttcc tatttgtagt ataatgaggc ttgtattgct tttagactaa gcttagaaaa
    10741 gagaaaaaca atgtcagatt taacacaaga gatgacctta aatgttatta gtatttttga
    10801 taattaccaa attgaacttg ctgaaaaagg acaccttatt ttaagtactg aagtgactga
    10861 gacggctttg aattattatg ggaatgccca tggtggttat cttttcaccc tatgtgatca
    10921 agtaggtggt ttggttgcta gaactactgg cgtagaatct gtcaccttac aggccaatgc
    10981 taactattta aaagcagggc acaagggaga caagctgatg gttgaaggtc gattggttca
    11041 tggaggtcga accacgcagg tggttgatgt gacgattcat aaccaaacag gagctcttct
    11101 aacaaaaaca agcttgacca tgtttgtgac tggccgacgt cataacgggt gattaatgaa
    11161 tcaataaagg aaaaaagtcc caactctctg agaattggga cttttttcct ttattgagag
    11221 ataccataaa tcacccgtta gacggatggt tacggtttat ttacggtaaa gtttgtgatg
    11281 ttggtaaaca gggtcaaagg taatatttac cccaagtttt cggagtacat ttttatcttc
    11341 ttcggttaag ataacggtag aatgggcttc actacctttc aaattgccga gttctttcat
    11401 ggctagatta gcttcttcac tagtcatagc agtaatggcc aacgcaatca gaatttcatt
    11461 ggaatgaagc cgcggattgt gactgcctaa gtggttcact ttgaggcctt gaataggttt
    11521 cacgtattcg ggttcaatca aatgagtggt tttatcaatc tttgccaagg ttttaatcgc
    11581 attgatgata acagctgcag ttggtccaaa gagttcagat gttttacctg tcacaatctg
    11641 cccatttggt agttggagag caagggcagg ttggcctgtt tgctctgctt tttgatgagc
    11701 agctacagta acgtgacgat cgtcaggggt gacaccgata tcattcatta agagctcaat
    11761 ttttttgaca gcagattctg tgactcgctc tgccttgaaa tccacgaggg tttggtaata
    11821 acgacggatg atttcttgtt tagaagcttc gatagcagct tcttcattga cgatagaaaa
    11881 accaaccatg ttaacaccca tatcggttgg tgaggcataa ggagacttgc tcaaaatacg
    11941 ctcgaaggtc cgatttaaga caggaaagac ctcgatatca cggttgtaat taacggccgt
    12001 tttgccataa gtttccaaat ggaaggggtc aatcatattc acatcatcta ggtctgccgt
    12061 ggctgcctca taagccagat tgacagggtg atgaagagga agattccaaa ctgggaaggt
    12121 ttcaaattta gcatagccag acttaacccc attgatttgg tcgtgataca tttgggacat
    12181 gcaagtggct aattttccag acccagggcc tggtgctgta acaacgataa ggttacgact
    12241 cgttttgatg taatcatttt tccccatccc ctcagatgag ataatatgat taatatctgt
    12301 cgggtagccc ttgataggat aatgcaggta agaagcaatg ccattttttt cgagttgctt
    12361 gcgaaaggca tctgcagcgg gttggttatt gtattgagta ataacgacag aacctacgta
    12421 aatatctaac gtgttaaatt tgtcaattaa gcgaaagact tcttggtcat aagaaatgcc
    12481 taaatcacca cgcgctttag aatgttcaat attattagcg ttaatggcaa ttacaatttc
    12541 gacttgttct ttgagctctt tgagtaattt aatcttattg tcaggttcat agccaggaag
    12601 tacacgggca gcatggtaat cttctaacat tttaccacca aattccatgt aaagtttgcc
    12661 atcaaattgg ctgatacgtt ctaaaatatg atctctttgc aagtttaaat acttgttaga
    12721 atcaaaagca atagttttca ttttttcacc tctgtaaagc attataacaa agaaattcca
    12781 agaaagaaaa ggttttttgc agggatacct cattttgtga ctttttaaaa aaacttaggc
    12841 ttggttctta gaagaaaaat gtatccgcta tgttcaaaag aacttgacaa ttaaaatgag
    12901 ctttactata ctagtaacaa ttaaatacta ctttaaacat gttccgtgaa gcatgaaagt
    12961 cttaacatta aagagagttt ttttgtcatc tcttattatt tagtgaactt tgatggactt
    13021 gcggacttgt ttccaagtct ttttttgacc tttggacaaa gggtattcaa ttaattaagg
    13081 tagtcagtga gctactatta agaaggagac aattatgtca acattatcat tggacaccac
    13141 aaataagcga gctttagtgg cagctattgc agcttcagga acggatgact tgaatgtcat
    13201 gtttcttgcc ttttccatgt cttccattat gacagacttg agtcttagtg gcactcaggg
    13261 tggctggatt gcgaccatta ccaatttagg aatgttggtg ggaggcctct tattcgggtt
    13321 gctggctgat aggcaccaca agtttaaggt ctttaaatgg acgattttac tgttttcagt
    13381 agcaacagga ttaatttatt ttacccagtc tttgccctac ctgtacctga tgcgatttat
    13441 tgctggcata ggagttggag gtgagtacgg tgtagccatt gccataatgg cagggattgt
    13501 accaccagaa aaaatgggtc ggatgtcttc tttaaatggt attgctggcc agcttggctc
    13561 cattagttcg gctcttttag cagggtggct ggctccaagt ctaggctggc gtggcctttt
    13621 tctctttgga ttacttccga ttctcttggt gatttggatg actttagcca tagatgacca
    13681 aaaaatttgg gatcattatg ggcaagagga ggaagaatgc agtcaaccaa ttaaaatcaa
    13741 tgaactattc aaaacaaaat ccttaacagc tcaaaccctt gctttaatgg tcatgacgac
    13801 tgtgcagatt gcgggctatt ttggaatgat gaattggttg ccaaccatta ttcaaacaag
    13861 cttaaacctt tcagtaaaaa gttcgtcctt gtggatggtg gctactattg tcggcatgtg
    13921 tttggggatg ctgtgttttg gtcagctttt agattgcttt ggtccacgtc tgatttattc
    13981 cctcttttta ttagcatcat ctatttgtgt ttaccttttt caatttgcca attccatggc
    14041 gagtatggtt attggaggtg ctattgtcgg tttttttgtc aatgggatgt ttgctggcta
    14101 cggggctatg attaccagac tttatcccca tcacattcga tccacggcta ataatgttat
    14161 tttgaatgtt ggccgtgctc taggaggatt ttcgtccgtt gctattggta gtattttaga
    14221 tgcctcaggt atttcaatgg tcatgatttt cctagcttct ctgtatgtga ttagttttgg
    14281 agctatgtgg tctattggtc agttaaaagc agaacgctac caacaattgc gttagcaaag
    14341 agatgggtgt tagtatttga gttactttca ctcacaaagc tattttattg attgagataa
    14401 ccaaaaaggt aagcacttag ggattgctta cctttttggt tcttttcttt tgttttactc
    14461 cgctactttg gccataaaat gtttactgtt caccctaact ctagtatgac aggcttttcc
    14521 aatgagttgt tctcccacaa aagcttccaa gcggaaatcg tattttcggc cttcttcttt
    14581 aagggctgta atgatgattg taacaggatc tccaatggct gaagctgcca aatgttggat
    14641 agctatctcg ctgccaaccg ttgtaaagtc actgtcgagc tgttcttggg caaataagta
    14701 agaagcattt tccataaaag caacaagagc aggagtagct aggacattca gcgttcctga
    14761 gcccatggct ttagccgaat gattgggacg ggtttcataa gtgtgagaat aaatagtcat
    14821 aagttaatct cctcgtttct ataagcctat tataatatat taagcgctta cagtcatgaa
    14881 actactgttt ttttatgtta tacttaataa tgaattt
//
LOCUS       DAUCXI010000040        13954 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.040, whole genome shotgun sequence.
ACCESSION   DAUCXI010000040 DAUCXI010000000
VERSION     DAUCXI010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13954
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.040"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(116..2131)
                     /gene="recG"
                     /locus_tag="VGY43_001410"
     CDS             complement(116..2131)
                     /gene="recG"
                     /locus_tag="VGY43_001410"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEQ4302586.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENKSETNGLPILYSKHAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     HKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAKNIRKKEVYD"
     gene            complement(2506..3960)
                     /locus_tag="VGY43_001411"
     CDS             complement(2506..3960)
                     /locus_tag="VGY43_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302587.1"
                     /translation="MERLGGADLDYCYHNHHDTSMISAEQLVFTYHDQKNPACQVPTC
                     QIASGQFIVLCGPSGSGKSTFLKLLNGIIPDYYAGKYEGRLDVADCQAGRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQDLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAAGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            complement(3897..4577)
                     /locus_tag="VGY43_001412"
     CDS             complement(3897..4577)
                     /locus_tag="VGY43_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ4302588.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWHFPEVWLLTLAVMCRFIPMIRQECCVIHRSLTIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            complement(4574..5167)
                     /locus_tag="VGY43_001413"
     CDS             complement(4574..5167)
                     /locus_tag="VGY43_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEQ4302589.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPILLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSAFAHYLLKKHFIKSGLLS"
     gene            complement(5164..6834)
                     /locus_tag="VGY43_001414"
     CDS             complement(5164..6834)
                     /locus_tag="VGY43_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302590.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICHDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFDLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLSVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     RTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQDISDESIWNLA
                     EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACADHLFCVKNGFLKEVNKK"
     gene            complement(6827..8590)
                     /locus_tag="VGY43_001415"
     CDS             complement(6827..8590)
                     /locus_tag="VGY43_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEQ4302591.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLPLIPLSIVAMQKRSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQATERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSVPARKDN
                     KSKTAINFNQIDIQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLSQEIINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLPDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLSTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            complement(8587..9423)
                     /locus_tag="VGY43_001416"
     CDS             complement(8587..9423)
                     /locus_tag="VGY43_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302592.1"
                     /translation="MSKNSSHIQVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILKLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNDIRTQRRDRNK
                     NR"
     gene            complement(9420..10442)
                     /locus_tag="VGY43_001417"
     CDS             complement(9420..10442)
                     /locus_tag="VGY43_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEQ4302593.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYGAIVKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            complement(10444..11328)
                     /gene="isdE"
                     /locus_tag="VGY43_001418"
     CDS             complement(10444..11328)
                     /gene="isdE"
                     /locus_tag="VGY43_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEQ4302594.1"
                     /translation="MIKRCKGIGLALMVFFLVACVNQHSKTAKETEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSVNPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHP"
     gene            complement(11312..12187)
                     /locus_tag="VGY43_001419"
     CDS             complement(11312..12187)
                     /locus_tag="VGY43_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEQ4302595.1"
                     /translation="MTKVVIKQLLQVIVVFMISLSTMTGVVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQEVKDSQKPVDTKLGESQDESHTGAMITQNK
                     PKANSSNNKSLSDKKILPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKRKKNDKTM"
     gene            complement(12384..>13954)
                     /gene="shr"
                     /locus_tag="VGY43_001420"
     CDS             complement(12384..>13954)
                     /gene="shr"
                     /locus_tag="VGY43_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEQ4302596.1"
                     /translation="IFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSV
                     SPKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELV
                     SIEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKSSNGQYVTVDEKLLSNDPKDDL
                     TGEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHSHQKDLVENGLRAL
                     NQKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGVSYLEVEFRGIKVGKM
                     LGYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMK
                     LIEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQEN
                     SHLTSTDQLKGPQNRQQEKTPTSPPSAATGIANLTDLLAKKATGQSTQETSKTDDTDK
                     AEKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMI
                     VALGFIIGRKTLFK"
BASE COUNT         4471 a         2902 c         2356 g         4225 t
ORIGIN      
        1 gcagtctcat cgtaaagcat aagtaaaaaa ggtcagaaat agtgacctct ttatacttta
       61 taacagttta tctcaaagct aactaaatat ttgtaaaaca acgacttgtt ttaagttaat
      121 cataaacttc tttttttcta atattttttg ctactaattg ccactgtttt tcatatatcc
      181 agttaggatc agaaacaatc gctgcagaaa ctttgcgtgc ttcttctaaa ataggataat
      241 cctcaacgat atcagctact tgaaattctg gaattccaga ctgacgagta ccaaagattt
      301 caccagaacc acgcattttt aaatccgact cagccaaaac gaaaccatct gtcgtttctg
      361 tcatgattgt cattcgtttt ttccccgaat ccgttttggg attagccact aaaacagcgt
      421 atgattgttt atgtccacga ccaacacgcc cacgaagttg atgtaactga cttagtccaa
      481 aacgatcggc atccataata atcatgatcg ttgcatttgg gacatttacc cctacttcaa
      541 taactgttgt ggatactaaa atatgacttt ttttatcctt gaaatcttgc attatggcat
      601 ctttttcatc atttttcata cgtccatgta caagagcaac cttagcaatt ccttcaaaat
      661 aagtagataa ttcggcatgc aatgctactg cattctttaa atctaaagct tctgattctt
      721 caatcaacgg tgaaatgaca tacacttgag catctttttg caattcacct tttacccatt
      781 ccaacacagt ccctagctgc tcgtgtttca cccagcgtgt cataataggt ttacgaccgg
      841 caggtaattc atcaataaca gaaacatcca tttctccaaa agctgtgatt gctagagttc
      901 ggggaattgg ggtggctgtc atcattaaaa catcaggatt ttctcccttt tcacggaaaa
      961 ttctacgctg tttaacacca aaacgatgtt gctcgtctgt aatgacaagc cccagtttat
     1021 ggtactgtac cgagtcttgg ataagagcat gagttcctac aatcatatcc actgagccat
     1081 ttgcaatagc tgctaaaacc gtacgcttga cagcggcttt catacccgaa gttaatatag
     1141 caattgatag atctggaaat aactcttgca gactaatgta gtgttgttca gctaggattt
     1201 ccgttggaac catcaaagcc gattgaaaac ctgctgtata agctgcatac attgatagac
     1261 cagcaatgac tgtctttcct gatcctacat ctccttgcaa taaacgattc atatgagctc
     1321 ccgatgacat atcagataat atgtcatcta aagagcgctt ttgagcattt gttagaataa
     1381 agggtaaaga ggaaatcttt gtctccatag catgtttact ataaagaata ggcaaaccat
     1441 ttgtttcaga tttattttcg gctttcaaaa cttgaaggtt catttgaaag taaaataatt
     1501 cttcaaattt aatccgacgg agcgcttgct tatactctgt gatatctttt gggaaatgca
     1561 tagctaaaca agcctgacta cgacccatca atcggtattt ttccaataaa gtagctggta
     1621 aattttcctt caattccaaa tgcgcatcga tttcaaaagc tgacttaata gctttaatca
     1681 aagtagactg tgaaattccc tgagctacgc gataaacagg ttgcatgtca tcttcaactt
     1741 gagctaaaac cttcatccca gtaatagccg atttagtggc atcccattta ccaaaaacag
     1801 ctacctcttg accaagttct attttatcag ctaaataggg ttgattaaaa aaactaacat
     1861 ttaagacagc ttccccttga cgcaatttga aacttaaacg gttacgttta aaaccataat
     1921 attgtacatt agctggagta acgactaagc ctgtaatgac tgctttttca ccatccacta
     1981 aatcaaaaac agattttgat ttaaaatctt catagcgaaa cggataataa agcagtaaat
     2041 cttctactgt ataaatatct aatttctgaa atttttctgc tgattttggt ccaaatccct
     2101 ttaagttgga cataggagct gttaatatca ttatcttttt cccttcacaa aaactcttgt
     2161 cagattgaag acaaagtttg tcgtgatact ttccttaggt ggtgcttacg gcagcgacgt
     2221 tctttggaat tccctgcctt tatttttgag cctgaggtct caaaaatccc gagtggcgtc
     2281 aatctcgtat tgacgccact cttttaccac agcaaaaagc atctgttttg gctcacttta
     2341 tatgtaaaaa tcggaaaccg aatgtcaaat cagcagagct atgcatgctt tttgaacata
     2401 aaactggggt tgtctacgtt ctgactcttg tatctattat acaagagttc ctatttattt
     2461 tcagataaaa gccttttagt acttttaaac agttctaggg gatcgttaag gtagcatttg
     2521 ataaatggta tcgcagacac tacttagaag ttcttcatca tgtgaaatga ggatgacaac
     2581 cttatgttgg gtcttcagct gcatgagaag attagctaaa gccttcattt gtaacaaatc
     2641 aagtccgcta cttggctcat caaaaattaa gatatcttta tcagccaaaa gactagcggc
     2701 aatcatcact ctttgttgct cacctcctga caaactagct ggatgacgtt ctaaaagagt
     2761 cgttaaagat aaccgctcta ttacttctgt cgtccgtgga tgtcgttcat ggcccaagtt
     2821 gacttccttt gaaaccgatt ctgcaaatag ttgcaaagaa acttcttgca agacaatact
     2881 agtctttgat aaacgttgct tggcagataa aggtatgcct tgaaacttaa tagttgcttt
     2941 tttatcgtct aagataccag ctatataata aactaattgc gattttccaa gcccgtttga
     3001 tcctgtaatg ccagaaatac ttcctgcagc aaaactaagc tgttcaatac atctaagtat
     3061 tttgcttccc gctctaactg ttagatgctc aatacacagg ctatcatctg ggcgataatg
     3121 ttgactctca atcttaccag ctaacacagg ttttaggtca gacaagtcta agcgacgtag
     3181 tcccatatct tgccgttgtt catctgtcaa ggctagcaaa tcttgtgttg ttaacttatc
     3241 tgttaatcta ccatttttaa agtagaaaaa gttatctgcc aaatccatca agtaatgtaa
     3301 acgatgctcg gctacaataa tggtttttcc tgctgctttt aattgggtaa gataggcttt
     3361 aacagcagct atgcctgcac tatctaagtt agcagttggc tcatcaaaaa gcataatatt
     3421 agtaccttgc ataatggccg ttgcaatagc aactctttgt ttttgccctc ctgacaatcc
     3481 aaacatatcc ttgttaagga gctctgcaaa agcaaaatct tctgctaaag tccaaagacg
     3541 cttcatgata acctttgcat ctagaccttg attttcacag ggaaagacca gttcgtgttg
     3601 gacttcgcga tagaaaaact gactggctgg attttgaaaa acagaggcca cagatctaga
     3661 aaatgtttca acactgtctc tgcctgcttg gcaatcagcc acatctagtc taccttcata
     3721 ttttccagca taataatcag gaattatgcc attaagaagt tttaaaaagg tagatttacc
     3781 tgaaccagaa ggtccacaca aaacaatgaa ttgtccagat gcaatttgac aagtcggtac
     3841 ctgacaagct ggattttttt gatcatgata ggtaaaaaca agttgttctg ctgaaatcat
     3901 tgaagtatcg tgatgattat gataacagta atccaaatct gcacccccca atctttccat
     3961 gttaagtgtg agctaaagca ttcactggtg cctttgttga ctgctagccc tttagttaga
     4021 ctagcgatag ttagttcttg gctacttctt atcaaagata aaagcaatgg aaccattaaa
     4081 tactccaagt attgtttagg tctgatcaaa atagaccatt ttgttaaaat aatccccctg
     4141 attgttaaag agcgatgaat aacacaacat tcttgtctaa tcattggtat gaaacggcac
     4201 ataacggcta aggtcaatag ccagacttct gggaaatgcc atttgcgtaa tccatgaacc
     4261 aattcgtaga tggtagttgt cttaatagta attaaacctg ctagtaaaga agggaaaact
     4321 aaccttcctg ctattgagac aaaactcaat aagtgatcaa gataagaagg gaaaatagat
     4381 agcgggatta cagatagacc gatcattaac agataaacaa ccgccaactt gaacgctagc
     4441 tttttcttat ttaaagcaga caaaagtaat aagagaaaaa taacaattat aaattctaaa
     4501 aagccatcaa cacgaaaaaa gaagcaggca ttggcaagta ccaacaaaag cagtttggtg
     4561 cgaacatcaa gcctcatgat aacaatcctg atttgataaa atgtttcttt agtaaataat
     4621 gtgcaaaagc tgaccctaat aaggctcctg caagaacaat tcctacaaac caaataacat
     4681 gccctaaact aaaatcatac ataatgcgat tgacataggt catactttta ccgcgggcta
     4741 acaaactttc aacataggca tctttcaaca accacatcag caaaataggg ccactattga
     4801 caaaagcaaa aaccatataa gataggtcat taaaaaacct tgacttgtat tttcctaaag
     4861 aagcaataat atccgctatt aaaccgaaaa taatgctggg aaacatcgcg gcaaaaaagt
     4921 gaccactaag gaagaaaaaa cctcccatca tcagtcctaa taatgttatt ggcccaaatg
     4981 tttgcaattt agcaatcaaa agaaaataaa ttgttccccc cagtaaagct gcaaaggcag
     5041 gggcatataa catatttcct gagcgatcaa aaaagatgtt aataaacgtg cctagaccaa
     5101 cacaaataaa gtagagcgcg gcaaatgcgc ctgttatcat aatatctttt attgttaact
     5161 gtttcatttt ttattcacct cttttaggaa accatttttt acgcaaaata gatgatcagc
     5221 acaagctagg gttgatggcc tgtgagaaat taagaagacc aatccttgac aatgtgtttt
     5281 aattaaatca agcaagatag cttcatttag agaatctaaa tttgacgtgg gttcatcaaa
     5341 aatatagcaa ctcgcatctt tcaataaagc tcgcatcaac tctaaacgtt gaccttctcc
     5401 agctgaaaag tcagaaggac tcttgataat cgtatccaaa ccttccttac aagctaacag
     5461 tctgtctttc ataccacaag cctcagctaa attccaaatg gactcatctg aaatatcttg
     5521 acggccaaag gtaagatttt cacggataga ctgttggaaa agctgcgctg tttgtggcac
     5581 ataagcaata gtatcttgta atttagcagc atttagtaag caactattcc tatcattaag
     5641 aaaaatatct cctgtcctcc aattatacca tttcataatt aatttcacca aagttgattt
     5701 accagatcct gattcgcctt taatgccaat aatccccttt tcttgaaagg taactgataa
     5761 atccttaaaa accagctctt ggcgctttgg ataagcaaaa ctgaggtcct caaaagaaac
     5821 actccttaaa cgatctatct gttttgtgcc ttcgtctact atgacatttt cgtctagaag
     5881 gtcaaaaata tttcgagccg cattcatagc acgcttaaag cctaatggca aacgtcctag
     5941 ttctaaaaaa ggagaaaacg aagcagtgaa agcaataaaa gttaataagc ctttatcaaa
     6001 tgataagctg tcatggcata tcccatcaaa aaccatataa gaaaatgcta agatcattaa
     6061 gccaagccag aaaaaagtca atgccatttg caaaaattga gcttgcgcta cgttacgatc
     6121 aagagcattt acatgattac ttttttttat taatcgttca aattgctcgt ctaatacctg
     6181 aaattgcaaa agatctttga ctgatcgtaa actctctaaa aaataagaca ggtaatcttt
     6241 tcgaccttca ttttggcttt ttagtaaaac ctgtaaaata ttagcaaaat aaatgggtat
     6301 aacaatggct aaacaagcat aggttgccaa agctaataag gctaactgcc aactactttg
     6361 acaaaagtac cagaacatta aacctgcaga caatattgct gtacaaatag gcgcgattgt
     6421 gtgggcaaaa aaaacttcta atgcctcaat atcttctcca atcattttaa gcaaataacc
     6481 actgtcttga ctatccaagc aagctggaga aagagctctt agtttcttaa agatcaagtt
     6541 cctaaaagct gctaaactat gaaaagcaac aaaatgacca aaataatgct ctccataacg
     6601 aacaaaacct cttaaaaagg ctagagcaat caaaagatat aaagctaata ttggaatcac
     6661 ttcttgtcta atagctagta gtcctaaata agctattcca gttggaatac ttaccgtgat
     6721 gacaaaaccc ataacagcaa agccaacagc caagataatc caaggtagca gagttttcat
     6781 tagggttaat aaacgccaaa ccaggcttaa ggtagatctg ttaggtttag ccataaatac
     6841 ttgcctccag tcttgcttga gtatcaacta ggtgacgata agttggttgg tcccgataaa
     6901 ggtcgcaagg tttgcctaaa caagcaggct gccctgtgct taaaaagagt acttggttag
     6961 ctcctttcag tcgagacatc ttatgagtaa tcacaataac tattgccgtc ttagctaatc
     7021 tcgttattaa attgtcaata atacgttcat tttctgcatc tagactagat gttgcctcat
     7081 caaagatata aagagacctc ttacttaata gagctcttgc gcaaatcacc tgttgctttt
     7141 ggcctggtga taacaggtta ccattttcac caactattgt gtcaaggcca tctggtagcc
     7201 agttgatgaa gcttaacaaa ccatgttgat ctatccaatc taagatttct tttttagaga
     7261 gatttgcggc taaccttaaa ttatcgtaaa tgctacggtt caataaggta gattggtccg
     7321 atacataaag aacctgctgg ttgataattt cttgcgacaa attgtcactg tctaaaccgt
     7381 caaataaaat atgcccagtc gttgcagact ggcgtttcaa gaggagttga gctagacttg
     7441 tttttccttg tcctgacacc cccgcgatag ctgttagttg gcccttcgtt aatgtcatgg
     7501 taaccccact aagcactgtt tttttctcat aagctaaaga aatattttgg atgtcaatct
     7561 ggttaaagtt tattgctgtt ttactcttgt tatctttcct tgctggaaca ctatccaaga
     7621 aactaaagat acggtcagcc attttggtat tcatcatgac caagtgcatg ccataaccct
     7681 gctcacgaat cggtgtaaaa aattctgtag caatcaagag aaaaaagagg aaattaaaaa
     7741 aagataactg acctgttgcc aaagcttgaa cggctaaaaa acctgacaaa ccaattccca
     7801 gatacataac tgcatccata taaccaactg cttgtaactg aaagccaagc aaagacatgg
     7861 tagcctttcg aaactgttct gccttacccg aaaattcttg ctcgtaacgt tctgttgctt
     7921 gataagaata cagtgtatta agacctttta agtcatccat aaataaatta ccaacatcca
     7981 tataagaaga ccaataatga ctcataattt gcttagaccg cttttgcata gcaacgattg
     8041 aaagtggaat cagaggcaga actcctaaaa agacaaggcc tgccaatgga taaattaaaa
     8101 agactagtat cataatagtt gtgcagttcc acttggttct catagacaaa gacaaatagt
     8161 aaccataata agtatccaaa ctatcaatcc cctgtgaagc caacgttaaa atatcagcat
     8221 cactggcatg agcatcaaat tgcccgtcta aatcaataaa agcctcaaag aaagattgtt
     8281 tgagtgaatc tctagcaaat tgtgaagcga tcccttgcag ttgcttgcct aatatagcaa
     8341 gaacaaagcc taccacattt aaaagtagga gtaaacctgc caagcgtcct aaggcaatag
     8401 catgacccaa aataaaggtc gaaaacgttt tggcaatgag gtaaaaactg atcatcctca
     8461 tcacaaattg taaccaagat aaaaaggctg acacataaag caaatacctt tttggtgcaa
     8521 ttcgttcacg taatcgtttt aacagtcttt tcctttttcc ccttgatatt gtatcttctg
     8581 tttccatcat ctgttcttgt tcctatctct cctttgagtt ctaatatcat tggtttcatt
     8641 gaccaatgaa gtgaggacaa actgttgacc atttctctca acaaagggca attcaacacc
     8701 aaagacatct ctgataaact gttgatcaag gaggtctctt ggttgccctt gggcataaag
     8761 tcgcccatct ttcagtccaa taagatggtc tgaaagagac aaggcctgat tgatgtcatg
     8821 taatactaac acaatcgtta agcctagctc ttggttgatt ttagtaatca gcttgagaat
     8881 gtcaagctgg tacttaatat ccaaataagt cgttggctca tctaaaaaaa taatatctgt
     8941 atcctgggca agggccatag caatccaaac cctctgctgt tcaccaccag aaaggtgttg
     9001 gatgtcacga taaacataat cactcaaagc cgttacttct aaggcccaag caaggcgttc
     9061 ctcatcttct ttggtagtag ttttaaaaaa agaacgacgg gcaagcctag ccatggctac
     9121 caattcaccc actaacaaac cttcgaccac ttgatggtat tggtgtacca ctgccacttt
     9181 tttcgcaaaa gccttgagag aaatcgttgc taattcttcc tgctcaagcc aaacctgccc
     9241 ttgttttaac ggaaggtttt tggttaataa ttgtaataag gttgacttgc cactgccatt
     9301 tgcccccata atagtggtaa ttttcccttt tggaatgcta aaggtcaggt catctaaaac
     9361 aagtttttcc tcataagcaa aggaaaggtt ttgcacctga atatgactgc tgttcttact
     9421 catataatat cagacctcct tagcaggtaa ataaagtaag gcccgcctac aatactcatt
     9481 ataatcgcag ggctaatttc caatgggtaa gcaagacttc ttcctaaagt atcggctagc
     9541 aaaaagacaa aggctccaag caaagctgaa aaaggaatta agatttggtg cttacttcca
     9601 accagcaagc ggctcatatg agggacaatc aagcctagga aagaaaccac tccaacgatc
     9661 gaagtggcta ccgaagccaa taaaacagca accaaggaaa ttcccaaccg taacgctgta
     9721 gcatcgattc ctaaatgacg aatcacctga tcatctaaaa gaagaaggtt acaggttttt
     9781 gacaataaca aagctagtaa caagccaatg aatgtataag ggaataaaac ccctacatca
     9841 gcccatgttt tttgactaat atgacctgct aaaagagcat tgaccatggg actagctgag
     9901 gtgaaaaaac tggttaaagc agttgataac cccataaata aagcattaat agcaatccct
     9961 gttagaataa gccgaatagg attaagccct ttcttccatg ctaaaccata aatcagcagg
    10021 aaagacactc cgcctcctaa aaaggatacg attggaccat acagcagcaa ctgcggtaga
    10081 agtaaactag agactaaaac cataaaacta gcaccactac aaatccctat aatagcaggg
    10141 tctgaaatag gatttttcaa cactgcttga aaaagaactc ccgaaacagc tatccctgct
    10201 cctgctaata aagcaatgac aatccttgga aaacgcaaat cataaatcaa agccacttgg
    10261 gggtcataag ccacaaacag tcccttgaca attgccccat aagaaaccgc caaaccacca
    10321 agggataagg caataaccgc caaaaatagg aggctgagaa ttaaaagaac tagataaaga
    10381 ccacttctga aacgtttttt agccagtagg gattgatccc tttgtaaatc tgatgctgtc
    10441 atgttacgga tgatctccca cgtggtcaaa aagctgtgtt aaggtgtcca aggcttctgg
    10501 gtagttcaat ttagcactca tgccaaacag ggtattgtcc aaatcataga ctttcccttc
    10561 cttgactgcc gtaaaatgtt tccaaatatc attttcagca aattctttgt caaacatcac
    10621 ttttaccttg tctggaatgg cgtgagctgt tcgtaaaatc aagtcaggct ccttagccag
    10681 catgtcttca ggattaactg atagaaattc tttctcatct gactgataaa cattctcacc
    10741 acctgccaaa tccaaaagat tccctacata agattggttc gtcgccacca aataactacc
    10801 tggcaagccc ataagaataa gcactttagg ctttttcttc cccttacgtt tagcttggaa
    10861 agcacgataa tagtcctggt attgctggcg caattctttt gcttcttgtt gacgttggaa
    10921 aaggttccct aaatcatcaa tggactggta catgccctca acacttcgta agttcaaaaa
    10981 accatactca gtatccaatt tttgatactt gggttccaaa tcttcttgta aagaattggg
    11041 actcaaaatc caagttggtt tcaaagaagc aatcaactct atatcaggat tcatgggtaa
    11101 acccacacgc ttaacagcat catagcgttt aggaagggta tataatttac tatcacaaac
    11161 cccaacgagg tctaaattta aacggtcaca gatatcaacc acagcaaccg aagtggctac
    11221 aattctctgc tgttcagtct ctttagccgt tttagagtgc tgattcacac aagctaccaa
    11281 aaagaagacc attaaggcta gaccaattcc tttacatcgt tttatcattt tttttcctct
    11341 ttttccaaac ccatacagca aaccctccta acatcagaaa aaaagttgga aagtagtaaa
    11401 tcatgattga taagtctttt ttagaccgaa acttatcttc tttttttaac tctaaagaag
    11461 tcgttaagcc catcttagaa ggaagaattt ttttatctga tagactctta ttatttgatg
    11521 agttggcttt aggcttattc tgagttatca tagcacctgt gtgagactca tcttgacttt
    11581 ctcctagttt tgtatcaaca ggcttttgac tgtcttttac ttcttgattt tgagaattgt
    11641 ctgtttcagt aacaagctgg gccaacatat tacctgaata cttttgtatt aactctgaag
    11701 ctgacaggta aaagaccact tctctgccca taggttcaac aaacatgctt cctcgaatga
    11761 tactatttac agtaggcaaa ctaatagcaa tatctagtgt tgtcccattg gtatcagtac
    11821 ctttttgggt gatattgtaa tccactgcct gaaagcttcc agttcctcca ggttgtatcc
    11881 agaactgata attgcccgaa taatcagcta agctcatacg aaaagtaaga acgatctttc
    11941 cagcatcaga tacttctagc atggcatcac tatagacagt cccttcaacc ataccttgac
    12001 caatatcaaa ggaatgctcc cctccgctat cttctatctg cccagatatc ggatgacgat
    12061 aatttctctg aataatacat ccataaattt gacctttatc tgcatacaca acacctgtca
    12121 ttgtcgataa acttatcatg aacactacta ttacctgcaa caattgcttt attactacct
    12181 ttgtcatatg ctcctcttgt ctatcttttc ttaaacatct tatttcattt tttaaatgaa
    12241 tcccatttta taacatctcc aaatgtgaaa aacacaccta tcttgcgact acttcaacct
    12301 gtatcaggag tcctgtcgga aataggtatg tttttagctc ttgctgacta gcttttttgt
    12361 tatttcactt ggtactaagt ttcttattta aataatgtct ttcgaccaat aatgaatccc
    12421 agagctacga tcataaagct agatagacct gcaattaagt gataacgaga gctactttct
    12481 tcaccatttg attgttgatt ggaacgatgt ttcttatcag attttttagt cttagtatct
    12541 tttgccgttt taccttcaat tgatgtttga tgatcacgca ctaactgctt caatttctct
    12601 gccttatcag tatcatctgt cttagaagtt tcttgagttg attggccggt tgctttttta
    12661 gccaggagat cagttaagtt agcaatacca gtagctgctg aaggaggact tgtaggtgtt
    12721 ttttcttgtt gacgattttg aggtcctttc aactgatctg ttgaagttag atggctattt
    12781 tcttgtggat tattagtttc tttgacaacc tttgccttct ctgttgtaag gcttgcccag
    12841 tctaaacgca taaaaacggt ttgaaggcca gacccttttg aaatggcatc catgataggc
    12901 acaaagacct gtaatggcac aagtccgtct ttcttcgctt gttcaatcaa tttcatacgc
    12961 agcacttttg gatagttttt tccataacga tctgccaatg gtaggccagt tacatccgtg
    13021 aaataagaca caacctctgc cttttttgtt cgaccaactg gtttaccagc taaatctctt
    13081 tggtaaccat ctacgaaata gctcaattca ccaaggtagc ctaacatttt accaaccttt
    13141 atacctctaa actcaacttc taaataggaa acaccttttt taactaccaa agtcactcga
    13201 tgattaatag ccttgtttga catggactca gatgctaagt cagtttttaa catgctggca
    13261 tttaaatagt aaataccatc acgcaattgt ttttgattta atgctctaag gccgttctca
    13321 actaaatctt tctgatgtga atgtggtcct ttcgccacaa ggatatcatt agatgtcaaa
    13381 tagatatgtt ctttttgagt agcaaatttc tttgttatta aagctttgcg aatccgatat
    13441 gtacctggat cttttaaaga aaactctccc gttaagtcat ctttcggatc atttgagaga
    13501 agcttttcgt caaccgtcac atactgtcca ttggaagatt ttttttgcaa ctgaatcaca
    13561 atactccaat cgacttgcat atcattaagt aaagaaacag tatctgaacc tttttcttgt
    13621 aacaattgtt gatattcttc aatagacact agttctttat caatggcaga atttgttttt
    13681 tgctcccaat aatacaaatc taaaagactg aaagcttgat gatattttat tttttcgcca
    13741 tctaaagaag cttcaagttt tgcaatatgt ttttgtggag tcagtttgtg ttgtccgata
    13801 agagctctta cttttggact cacacttttt atctgattga acttcacatc taaattaagc
    13861 gtttcaacat ctggaaatac tgattcttca acctgagtaa gcaagttatt gaaaaaatca
    13921 agttttgtta attggttatt ctgtttaaat atac
//
LOCUS       DAUCXI010000041        13941 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.041, whole genome shotgun sequence.
ACCESSION   DAUCXI010000041 DAUCXI010000000
VERSION     DAUCXI010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13941
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.041"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            246..560
                     /locus_tag="VGY43_001421"
     CDS             246..560
                     /locus_tag="VGY43_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEQ4302597.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            576..962
                     /locus_tag="VGY43_001422"
     CDS             576..962
                     /locus_tag="VGY43_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEQ4302598.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            991..2376
                     /locus_tag="VGY43_001423"
     CDS             991..2376
                     /locus_tag="VGY43_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEQ4302599.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTMASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2379..2531
                     /locus_tag="VGY43_001424"
     CDS             2379..2531
                     /locus_tag="VGY43_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEQ4302600.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2554..3759
                     /locus_tag="VGY43_001425"
     CDS             2554..3759
                     /locus_tag="VGY43_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEQ4302601.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            3802..4023
                     /locus_tag="VGY43_001426"
     CDS             3802..4023
                     /locus_tag="VGY43_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302602.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4140..4637
                     /locus_tag="VGY43_001427"
     CDS             4140..4637
                     /locus_tag="VGY43_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEQ4302603.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            4612..5118
                     /locus_tag="VGY43_001428"
     CDS             4612..5118
                     /locus_tag="VGY43_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEQ4302604.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5102..7549
                     /locus_tag="VGY43_001429"
     CDS             5102..7549
                     /locus_tag="VGY43_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEQ4302605.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7552..9729
                     /locus_tag="VGY43_001430"
     CDS             7552..9729
                     /locus_tag="VGY43_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEQ4302606.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            9726..10727
                     /locus_tag="VGY43_001431"
     CDS             9726..10727
                     /locus_tag="VGY43_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEQ4302607.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            10724..11604
                     /locus_tag="VGY43_001432"
                     /pseudo
     CDS             10724..11604
                     /locus_tag="VGY43_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            11849..11965
                     /locus_tag="VGY43_001433"
     CDS             11849..11965
                     /locus_tag="VGY43_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEQ4302608.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            11981..13900
                     /gene="tet(M)"
                     /locus_tag="VGY43_001434"
     CDS             11981..13900
                     /gene="tet(M)"
                     /locus_tag="VGY43_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEQ4302609.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT         4457 a         2557 c         2972 g         3955 t
ORIGIN      
        1 tacttatgaa tgagctttga tacgacgatt tatccttgaa aagtgaagat ataaagatac
       61 ttccaataaa atttgaatat ttaataggta gacacttcaa aaaatgaggt gtctattttt
      121 ttacccgatt ttgaaaggaa gtgaacttat gaaaacaaaa aatcaagaat caaaaggtcg
      181 ttccccactc tttaagacca tcaaacattc attcagccaa taaaaaagaa aggataggta
      241 aaaatatgga acttaaattt gtgattccca acatggaaaa aacattcggc aatttagaat
      301 ttgctggcga ggataaagtc gttcagcgaa gaatcaacgg acggctaact gtcttatcaa
      361 gaagctataa tctctattct gatgttcaaa gagcagatga tattgtggtg gtgcttcctg
      421 ctgaagctgg cgaaaaacat ttcggctttg aggaacgtgt gaagttagtc aatccacgta
      481 ttaccgcaga gggctacaaa atcggcactc gtggttttac aaattacctt ttacatgctg
      541 acgacatgat aaaagaataa agaaagagag gaaaaatgat gagattagca aatggcattg
      601 tattagataa agacacgact tttggagaat tgaaattctc tgctctacgt cgtgaagtga
      661 gaatccaaaa tgaagacggg tcggtttcag atgaaatcaa ggaacgtacc tatgacttaa
      721 aatccaaagg acaaggacgc atgattcaag taagtattcc tgccagcgtg cctttgaaag
      781 agtttgatta taacgcacgg gtggaactta tcaatcccat tgcggacacc gttgctactg
      841 ccacctatca aggagcagat gttgactggt atatcaaggc agacgatatt gtgctgacaa
      901 aggattctag ttcattcaaa gctcaaccac aagcaaagaa agaaccgaca caagacaaat
      961 agtcgctagg tagaaaggag actttttcgc atgaaacagc gtggtaaaag gattcgccca
     1021 tctggtaaag atttagtctt tcattttacg atagcgtcac tcctgcctgt tttcctgctg
     1081 gttgtcggac tgtttcatgt gaagacaatc cagcagatca actggcagga ttttaaccta
     1141 tcacaagcag ataagattga cattccctat ttaattatca gtttcagtgt cgcaattctt
     1201 atctgcttgc tggtagcgtt tgtattcaaa cgggttcgct atgatacggt taaacaactt
     1261 taccaccgtc aaaaactggc aaagatgata cttgaaaaca agtggtatga atctgaacag
     1321 gtcaaaacag agggtttctt taaagatagt gctggtcgta caaaggaaaa gataacctac
     1381 ttccctaaaa tgtattatcg acttaaaaat ggcttgatac agatacgggt ggaaatcacg
     1441 ctgggaaaat atcaagacca actcttacac ttggaaaaga aattagagag tggcttgtac
     1501 tgtgagctga cggataaaga gttaaaggat tcctatgtgg aatatacttt gctctatgac
     1561 accatggcca gtcgtatttc tattgatgaa gtagaagcta aagatggtaa acttcgctta
     1621 atgaaaaacg tatggtggga atatgataag ctccctcata tgttgattgc tggtggtaca
     1681 ggtggcggta aaacttactt tatactgaca ctgattgaag ccttgcttca tacagattca
     1741 aaactgtata ttcttgaccc gaaaaatgct gaccttgcgg acttaggttc tgtgatggca
     1801 aatgtctact atagaaaaga agacttgctt tcttgcattg aaacattcta tgaagaaatg
     1861 atgaaacgta gtgaggaaat gaagcagatg aagaactata agactggcaa aaattatgct
     1921 tacttaggtc tcccggcaca cttcttaatc tttgatgaat acgtcgcttt catggaaatg
     1981 ctgggaacaa aagaaaacac cgcagttatg aataagctga aacagattgt catgttaggt
     2041 cgtcaagctg gcttctttct aatactggct tgtcaacgtc cagacgcaaa atatttaggc
     2101 gacggaatcc gtgatcagtt taatttcaga gtggctttag gtcgtatgtc tgaaatgggc
     2161 tatggcatga tgtttggcag tgacgtacaa aaggatttct tcttaaagcg aatcaaaggt
     2221 cgtggctatg ttgatgtagg aacaagtgtc atatcagagt tttatactcc ccttgtacca
     2281 aaaggatatg atttcttgga ggaaattaaa aagttatcca acagcagaca gtccacgcag
     2341 gcgacgtgcg aagcggaagt cgcaggtgtg gactgatctt gctggctggt gtggcaatag
     2401 ccacgccagc acttaacccc ccgtatctaa caggggggta caaatcgaca ggaaacagtc
     2461 aaaaaaacat tagaaaatcc tttggttaca agggatttac aaaatttcag cgtatgtcaa
     2521 atgggcttta aaagttgaca tacgcctttt tgattggagg gatttttact gaatgaacaa
     2581 acttggttac agcatttaaa agaaaaacgc ttggcttatg gactatctca aaaccgttta
     2641 gctgttgcga ctggtattac aaggcagtat ctaagcgata ttgaaacagg aaaagtcaag
     2701 ccatcagagg atttacagca gtccctttgg gaagctctgg aacgcttcaa tcccgacgct
     2761 ccccttgaaa tgctgtttga ttatgtaagg attcgctttc cgacaacaga cgtacagcag
     2821 gtggtcgaaa acatcttaca actgaaactg tcctattttc ttcatgagga ctatggtttc
     2881 tattcttatt cagagcatta tgctttaggc gacatattcg tcctttgctc ccatgaactg
     2941 gacaaaggag ttctggtgga attgaaaggt cgtgggtgca gacaatttga aagctatctt
     3001 ctggcacaac aaagaagctg gtatgagttc tttatggacg ttttggtggc tggcggtgtg
     3061 atgaaacgcc ttgaccttgc cattaacgat aagacaggga ttttgaatat ccctgtactc
     3121 actgaaaagt gccaacagga agaatgtatc tccgtcttcc gcagttttaa aagctatcgc
     3181 agtggcgaac tggtacgcaa agaggaaaag gaatgtatgg gaaacaccct ctatatcggt
     3241 tcattacaaa gtgaagttta tttctgtatc tatgaaaagg actacgagca gtacaagaaa
     3301 aatgatattc ccattgaaga cgcagaagta aaaaaccgtt ttgagattcg attgaaaaat
     3361 gagcgtgcct attatgcagt ccgtgattta ctcgtctatg acaatccaga gcataccgcc
     3421 tttaaaatta tcaatcggta tatccgtttt gtagataaag acgattccaa acctcgttct
     3481 gattggaaac tgaatgaaga atgggcttgg tttattggga acaatcgtga acgattaaaa
     3541 ctaaccacaa aaccagagcc ttactccttc caaaggacgc tgaactggct atctcatcaa
     3601 gttgccccga ccttaaaggt tgcgattaaa cttgatgaaa tcaaccagac gcaggttgta
     3661 aaagacattc tcgaccatgc gaaactgaca gaccgacaca agcagatttt gaagcaacag
     3721 tcagtaaaag aacaggacgt gataacaaca aaaaaataac tcaaatacaa attcattgaa
     3781 tatagagagg agaacatttt tatgaatttt ggacaaaacc tttataactg gtttctatca
     3841 aacgctcaat cactggtgct tttagcaatc gttgtgattg gcttgtatct tggcttcaag
     3901 cgtgagttta gcaaactgat tggcttttta attattgcga ttattgcggt tggcttagtc
     3961 ttcaacgctg ctggagtaaa agacatttta ctagagctat tcaatcgcat tattggtgct
     4021 taaataaaac cgttcttttg tggaatataa gtggttttct tatgttccgc aaaggaatgg
     4081 tacaccaaac gaagtgcggt agggattttt gaatctctac aaagaaagga cgtgaatata
     4141 tggacgatat gcaagtctat attgcgaatt taggcaaata caatgagggc gaattggtcg
     4201 gtgcgtggtt tacctttccc attgactttg aggaagtcaa agagaaaatc ggcttgaatg
     4261 atgaatatga ggaatacgcc attcatgact acgagttacc ctttacggtt gacgaataca
     4321 cttccattgg cgaactcaat cgactatggg aaatggtatc ggaattaccc gaagaattac
     4381 aatcggagct atctgctctg ctcactcatt tttcaagcat tgaagaacta agcgaacatc
     4441 aagaggatat tatcattcat tccgattgtg atgatatgta tgacgtggca cgctactaca
     4501 ttgaagaaac gggtgcttta ggcgaagtac cagctagtct tcaaaactat attgattatc
     4561 aagcctatgg tcgggattta gacctttcag gaacgtttat ctcaaccaat catgggattt
     4621 ttgaaatcgt ctattaaatc tgtcggtaca ttactactgg cagattttct attttacggg
     4681 gtggctcaat cagctacccc tattttttat gaaaggattg attacatgaa gaaaatacga
     4741 agctatacca gtatctggtc tgtggaaaag gtactgtatt ctatcaatga ttttagactt
     4801 ccgtttccca taacctttac gcaaatgaca tggtttgtcg tgtcactctt tgcagtgatg
     4861 atacttggca acttgccccc tctttccatg atagagggag catttctcaa atactttggg
     4921 attcctgtgg ctttcacatg gtttatgtct acaaaaactt ttgatggtaa aaagccttat
     4981 ggatttttga agtctgtcat tgcttatgca ctgcgaccaa agctgaccta tgcaggaaaa
     5041 aaagtaacgc ttggcagaaa ccagccacaa gaagccatta cagcagttag gagtgaattt
     5101 tatggcatat ccaattaaat acattgaaaa caatctcgtc tggaataaag acggggaatg
     5161 ttatgcttac tatgagcttg ttccttacaa ttactcattt ctaagtccag aacagaaaat
     5221 acaagtgcat gattctttca gacagcttat cgcacaaaat cgtgatggca aaattcatgc
     5281 tttacaaatc agtacagaat ccagcatacg ttctgcacaa gagcgttcca aaaatgaagt
     5341 cactggcaag ctcaaagcgg ttgcctatga caaaatcgac caacagacag acgctttaat
     5401 atccatgatt ggcgaaaatc aagtgaacta ccgtttcttt atcggcttta agttgcttct
     5461 caacgatcag gagttttcta tgaaaagtct taccgttgaa gcaaaaaatg ctttgtctga
     5521 ttttgtctat gatgtgaacc ataagctgat gggcgatttt gttagtatga gtaatgatga
     5581 aatcctgcgt tttcagaaga tggaaaagct cttagaaaat aaaatctctc gtcgtttcaa
     5641 aatccgcagg ttagataagg acgacttcgg ctatctgatt gaacaccttt acggacagac
     5701 aggcactgcc tatgaagagt atgagtacca tctatcaaag aaaaagctgg ataatgaaac
     5761 gctgattaaa tactatgact tgattaagcc tactcgctgt ttggtggaag aaaaacagcg
     5821 atatttgaaa atccagcagg aagatgaaac cgtctatgta gcttacttta ccattaacag
     5881 cattgtcgga gaactggact tcccgtcctc tgaaatcttc tactaccagc aacagcaatt
     5941 tacattcccg attgatacgt caatgaatgt ggaaattgta gcgaatcgta aagccctatc
     6001 tactgtccgc aataaaaaga aagaactgaa agacttggat aaccacgctt ggcaaagtga
     6061 taatgaaacc agctccaatg tggcggaagc tctggaaagt gtgaatgagc tggaaaccaa
     6121 tttagaccaa agcaaggaat ctatgtacaa gctgtcttat gtggtaaggg tatcagcaaa
     6181 tgatcttgac gaactcaaac gtcgttgtaa tgaagtgaaa gatttttatg acgatttaag
     6241 cgtaaaactg gtacgaccat ttggggatat gctcggctta catgaagaat ttttacctgc
     6301 cagcaagcgt tatatgaatg attatattca atacgtgacc tctgatttcc tcgctggttt
     6361 aggttttggt gctactcaaa tgctggggga aaatgagggg atttatgttg gctacagctt
     6421 agatactgga cgcaatgtct atctgaaacc tgctcttgcc agtcaagggg ttaagggttc
     6481 agtaaccaat gcgttagcgt cggcttttgt tggttcgctg ggtggtggta aatcctttgc
     6541 gaataacctt atcgtctatt atgcggtgct ttatggggca caagcagtga ttgtagaccc
     6601 aaaagcagaa cgtggcagat ggaaagaaac cttgccagag atttcccatg aaatcaatat
     6661 cgtcactctg acttctgatg agaaaaacaa aggcttactt gacccttatg tgattatgaa
     6721 aaatcccaaa gattctgaat cactggctat tgatattctg acattcctta cggggatttc
     6781 ctctcgtgat ggggaacgct tcccaatcct tagaaaagcc attcgtgcag taaccaatag
     6841 tgaagtacga gggttgatga aagtgattga ggaattacgg gttgagaata cgccactaag
     6901 taccagtata gccgaccata tcgaaagttt tacagactat gactttgcac atttattatt
     6961 cagtaatggt tatgtggagc agtctatcag cttagaaaaa caactgaaca ttatacaggt
     7021 tgcggacttg gtacttcccg acaaggaaac ttcctttgag gaatatacca ctatggagct
     7081 tttatccgtt gctatgctga ttgtcattag tacctttgct ttagacttta tccatacaga
     7141 ccgaagcatt ttcaagattg tagatttaga cgaagcatgg agctttttac aggtagcaca
     7201 aggaaaaaca ctatctatga agctggttcg ggctggtcgt gctatgaacg ctggggtata
     7261 tttcgtgacc caaaatacag acgacctctt agatgaaaaa ctgaaaaata acctcggctt
     7321 aaaatttgca tttcgttcca ctgaccttaa cgagattaaa aagaccttag ccttttttgg
     7381 tgtagaccca gaggacgaaa acaatcagaa gcgattgcgt gatttggaaa acgggcaatg
     7441 ccttatcagt gatttatatg gtcgtgtcgg tgtgatacag ttccaccctg tatttgaaga
     7501 actgctccat gcctttgata ccagaccacc tgtgcgaaaa gaggtgtaaa tgtgaaacca
     7561 tcaatagtaa acagaataaa atcaaactgg acgctgaaac gtctaggtaa agtggcaatg
     7621 acagtggctt tcacacttgt gattgccatt tttcttttag ccatgctggg aacggtggtt
     7681 caagctgcgg gcttggtaga tgatacggtc aatgtggcaa atgaatacag ccgataccca
     7741 cttgaaaact atcaactgga tttttatgtg gataatagct ggggctggct tccgtggaac
     7801 tggtcggacg ggattggaaa acaggtcatg tatggactat atgccattac caattttatt
     7861 tggacaatca gtttgtatgt ttccaatgcg acaggttact tagtacagga agcctattcc
     7921 ttagacttca tttccgctac agcagattcc attggtaaga atatgcagac cttagctggt
     7981 gtgagtgcaa acggattttc aacagagggt ttctatgttg gattcctctt actcttgatt
     8041 ttggttcttg gggtttatgt tgcctatacg ggactgataa agagagaaac cacaaaggca
     8101 attcatgcca ttatgaattt tgtgctggtg tttatcctat cggcttcctt tattgcctac
     8161 gctcccgact acattaaaaa aatcaatgac ttttcatcag acatcagtaa tgccagttta
     8221 tcacttggca cgaagattgt catgccccat tccgatagtc aaggcaagga cagcgtggac
     8281 ttaatcagag atagcctgtt ttccatacag gttcagcaac cgtggctact gcttcaatac
     8341 aacagttcag acattgaaag tatcggtatt gaccgtgtgg aaagcctgct ctccaccagc
     8401 ccagattcca acaatggcga agacagagaa aaaattgttg cggaagaaat tgaagacaga
     8461 agcaatacca atctaaccat tacaaagacc attaaccgtt taggtacagt cttcttccta
     8521 tttgtcttca atattgggat ttccatattt gtattcctat taacaggaat catgattttc
     8581 tcgcaggtac tttttatcat ctatgctatg tttctgcctg tgagctttat tttaagcatg
     8641 attccatcat ttgatggtat gtcaaaacga gccataacaa agctctttaa taccattttg
     8701 acacgagctg gaatcacatt gattattacg acagcattta gtatttcaac catgctctat
     8761 accttatcgg ctggttatcc gttctttttg attgcttttc tacagattgt gacctttgca
     8821 ggaatctact tcaagctggg cgatttaatg agtatgtttt ctctacagag taacgattct
     8881 caaagtgtgg gaagtcgtgt gatgagaaaa cctcgtatgc ttatgcacgc tcacatgcac
     8941 cgtctacagc ggaaacttgg acgttccatg actactctag gggctgggtc tgccattgtt
     9001 acaggtaaaa aaggacagtc gggttcgggg agttctgcaa ggacacaagc agatcactcc
     9061 cgaccagacg gaaaggaaaa atcaacactt ggaaaacgta tcggtcaaac catcggtaca
     9121 gtagctgata ccaaagacag aatggtagac actgctagtg gtttgaaaga acaggttaaa
     9181 gatttgccga ccaatgcaag atatgcagta tatcaaggaa aatccaaagt aaaagagaat
     9241 gtccgtgatt taaccagtag tatttctcaa accaaagcgg acagagccag tggacgcaag
     9301 gaacagcagg aacaaaggcg aaaaaccatt gcgaagcgtc gctctgaaat ggaacaggtc
     9361 aaacagaaaa aacagcctgc ttcttctgtt catgaaagac cgactacaag acaagaacaa
     9421 tatcatgatg aacagacctc aaaacagtct aatattcaga cttcatataa ggaatctcaa
     9481 caagccaaac aagagcgtcc agcagttaag tccgattttt caagtccaaa agtggaacgc
     9541 caaggcaata ccgttcaaga aaaaaccgtt caaaagccag caacttcaac cactacagca
     9601 gatagaactt cacaacgtcc aatcacaaaa gaacgtccgt ctactgttca aagagtacca
     9661 ctacaaaata caagaagtag accaccaatc aaaaccgcca ccattaagaa agtcggtaag
     9721 aaaccatgaa gttgaaaact ttagtgattg gtggttctgg attattcttg atggtcttct
     9781 cactgcttct gtttgttgcc attttatttt cagatgaaca ggacagcgga atttccaata
     9841 ttcattatgg aggtgtgaat gtttccgcag aagtgctggc tcataagcct atggtagaaa
     9901 aatatgccaa agaatatggc gttgaagaat atgtcaacat acttcttgcg attatacagg
     9961 tggaatcggg cggtactgcg gaagatgtta tgcagtcctc ggaatccctc ggtcttccac
    10021 ctaattcatt gagtacagaa gaatccatta agcaaggtgt gaagtatttc agtgaattat
    10081 tagccagtag cgaaaggctc agtgtagatt tagaatcggt tatccagtcc tacaattatg
    10141 gtggtggttt cttagggtat gtggctaatc gtggaaataa atataccttt gaactggctc
    10201 aaagtttctc aaaagagtat tcaggtggcg aaaaagtgtc ttaccccaat cccatagcca
    10261 tacctatcaa tgggggctgg cgatacaact atggcaatat gttttatgtg caactggtaa
    10321 cgcagtatct tgtcacaaca gagtttgatg atgatacggt acaagccatc atggacgaag
    10381 cactgaaata tgagggctgg cgatacgttt acggtggagc ttccccgact acttcttttg
    10441 attgtagcgg actgacacaa tggacgtatg gaaaagctgg aattaactta ccacgaaccg
    10501 cacaacagca atatgatgtg acccagcata tcccactatc ggaagcacaa gctggcgatt
    10561 tggttttctt tcattctacc tataacgctg gctcttatat tactcatgtt gggatatacc
    10621 ttggcaataa ccgtatgttt catgcaggcg acccaatcgg ttatgccgac ttaacaagcc
    10681 cctactggca acagcattta gtgggagcag gacgaatcaa acaatgagaa aggaagattt
    10741 aatgatgaaa tttagaaaaa atcagaataa agaaaaacag ataccaaagg aaaagaaacc
    10801 tcgtgtctat aaggtcaatc ctcataaaaa ggttgtgatt gccttgtggg tacttttagg
    10861 gcttagtttc agctttgcga tattcaagca ctttacagct atagatactc atactattca
    10921 cgaaacaact atcatagaaa aggaatacgt tgatactcat catgtagaaa attttgtaga
    10981 gaactttgcg aaagtctaaa aggctatctg acagatgaac ttcaagctct caatgttgat
    11041 acagtacgca aagatattcc tgtatcgtct tctgtaagag gatttcagat atggacggta
    11101 gagccaactg gcgacaatga gtttaatgta acctacagtg tagaccagct cattacagag
    11161 ggagaaaata caaagaccgt ccactctgct tatatagtga gtgtctatgt agatggttct
    11221 ggaaatatgg tactggttaa gaatccgacc attaccaaca tacctaagaa atcaagttat
    11281 aaaccaaaag ccattgaaag tgaggggacg gttgattcca ttacaaccaa tgaaatcaat
    11341 gagtttttaa cgacgttctt caagctctat cctacagcga cagccagtga actttcctac
    11401 tatgtgaatg acgggatatt aaaaccaatc ggaaaagagt acatctttca agaactggta
    11461 aatcctattc acaatcgtaa ggataatcaa gtcacggtat cgctgacagt ggagtatatc
    11521 gaccagcaga ccaaagcaac gcaggtatct caatttgatt tggtacttga aaagaacggg
    11581 agtaattgga agattataga ataacaaata ttggtacatt attacagcta ttttgtaatc
    11641 acgtactctc tttgataaaa aattggagat tcctttacaa atatgctctt acgtgctata
    11701 atttaagtat ctatttaaaa ggagttaata aatatgcggc aaggtattct taaataaact
    11761 gtcaatttga tagtgggaac aaataattgg atgtcctttt ttaggagggc ttagtttttt
    11821 gtacccagtt taagaatacc tttatcatgt gattctaaag tatccggaga atatctgtat
    11881 gctttgtatg cctatggtta tgcataaaaa tcccagtgat aagagtattt atcactggga
    11941 tttttatgcc cttttgggct tttgaatgga ggaaaatcac atgaaaatta ttaatattgg
    12001 agttttagct catgttgatg cgggaaaaac taccttaaca gaaagcttat tatataacag
    12061 tggagcgatt acagaattag gaagcgtgga caaaggtaca acgaggacgg ataatacgct
    12121 tttagaacgt cagagaggaa ttacaattca gacaggaata acctcttttc agtgggaaaa
    12181 tacgaaggtg aacatcatag acacgccagg acatatggat ttcttagcag aagtatatcg
    12241 ttcattatca gttttagatg gggcaattct actgatttct gcaaaagatg gcgtacaagc
    12301 acaaactcgt atattatttc atgcacttag gaaaatgggg attcccacaa tcttttttat
    12361 caataagatt gaccaaaatg gaattgattt atcaacggtt tatcaggata ttaaagagaa
    12421 actttctgcc gaaattgtaa tcaaacagaa ggtagaactg tatcctaata tgtgtgtgac
    12481 gaactttacc gaatctgaac aatgggatac ggtaatagag ggaaacgatg accttttaga
    12541 gaaatatatg tccggtaaat cattagaagc attggaactc gaacaagagg aaagcataag
    12601 atttcagaat tgttctctgt tccctcttta tcatggaagt gcaaaaagta atatagggat
    12661 tgataacctt atagaagtta ttactaataa attttattca tcaacacatc gaggtcagtc
    12721 tgaactttgc ggaaaagttt tcaaaattga gtattcggaa aaaagacagc gtcttgcata
    12781 tatacgtctt tatagtggcg tactgcattt gcgagattcg gttagaatat cggaaaagga
    12841 aaaaataaaa attacagaaa tgtatacttc aataaatggt gaattatgta aaatcgataa
    12901 ggcttattcc ggggaaattg ttattttgca gaatgagttt ttgaagttaa atagtgttct
    12961 tggagataca aagctattgc cacagagaga gagaattgaa aatcccctcc ctctgctgca
    13021 aacgactgtt gaaccgagca aacctcaaca aagggaaatg ttacttgatg cacttttaga
    13081 aatctccgac agtgacccgc ttctgcgata ttatgtggat tctgcgacac atgaaatcat
    13141 actttctttc ttagggaaag tacaaatgga agtgacttgt gctctgctgc aagaaaagta
    13201 tcatgtggag atagaaataa aagagcctac agtcatttat atggaaagac cgttaaaaaa
    13261 agcagagtat accattcaca tcgaagttcc accgaatcct ttctgggctt ccattggtct
    13321 atctgtagca cagcttccat tagggagcgg agtacagtat gagagctcgg tttctcttgg
    13381 atacttaaat caatcgtttc aaaatgcagt tatggagggg atacgctatg gctgtgaaca
    13441 aggattgtat ggttggaatg tgacggactg taaaatctgt tttaagtatg gcttatacta
    13501 tagccctgtt agtaccccag cagattttcg gatgcttgct cctattgtat tggaacaagt
    13561 cttaaaaaaa gctggaacag aattgttaga gccatatctt agttttaaaa tttatgcgcc
    13621 acaggaatat ctttcacgag catacaacga tgctcctaaa tattgtgcga acatcgtaga
    13681 cactcaattg aaaaataatg aggtcattct tagtggagaa atccctgctc ggtgtattca
    13741 agaatatcgt agtgatttaa ctttctttac aaatggacgt agtgtttgtt taacagagtt
    13801 aaaagggtac catgttacta ccggtgaacc tgtttgccag ccccgtcgtc caaatagtcg
    13861 gatagataaa gtacgatata tgttcaataa aataacttag tgtattttat gttgttatat
    13921 aaatatggtt tcttgttaaa t
//
LOCUS       DAUCXI010000042        12895 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.042, whole genome shotgun sequence.
ACCESSION   DAUCXI010000042 DAUCXI010000000
VERSION     DAUCXI010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12895
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.042"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            577..987
                     /locus_tag="VGY43_001435"
     CDS             577..987
                     /locus_tag="VGY43_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HEQ4302610.1"
                     /translation="MEAIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQNINQTSLTEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENQQD
                     LEDLYTYYMRTDTVSLLSSDLETSPQEVEMEIEL"
     gene            1035..7253
                     /locus_tag="VGY43_001436"
     CDS             1035..7253
                     /locus_tag="VGY43_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEQ4302611.1"
                     /translation="MEVMQLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     AEEGKIEEIPHVYSFHQDIVSFLEASSENNDQDLESYTRNFGQAGLGKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLTPLSELVCHQNQEVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELEKEVLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHYEGNYQQLPLT
                     QKLKIITHFDDVKARSEKSKQVEEAVLPLDNIDQVEENVEVHSLSKVDKIVEEALREY
                     PIGSQVSYKGQVFQLVSIENAQLNDLVRLELFNDSNQLFEENPILYLNSLEEIEQVLS
                     LVELEKEDSEIEIDSSSESQEIDLFSYLEEENEKDKETETLISSIEELDIPVQDFVFP
                     DDLEDFYPKTNREKIETNIAAIDLVKRLEKEGRQANPEEQELLAKYVGWGGLANEFFD
                     ELNPKYEAERLTLKSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFEGGRIL
                     DPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGEIAKQLHPNVHIEVRGFEEVPYQNN
                     SFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTMDKRT
                     DNVLQEIKTNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKNQAKNLNEEELVFSGSI
                     PFEEDKRVWINPYFDGKYNTQVLGEYEVRNFNGGTLNVKGESETLATEIMKAFENVEA
                     PKQIDNSLKAPVFIQEEVDNSIPSRIREDLALYSFGYEGNQIYYRDTHGIRKSSKVDE
                     ISYYVDEKGDFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGLFKKT
                     VFYESPLSDKDISRIKGMVDLRETYQSLIEIQRHPDYSRADFQVLLSKLNHDYDRFVS
                     QFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKSQKVKYKKSLAFEKALVRPERVIA
                     RVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILIDPESYLRGERKY
                     LSKNQFLSGDILNKIEVVQLLVEENNQEYDWSHALDLLESVRPPRIHLADIEFKIGSR
                     WIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNHVDGQVHLRTSFAYRYPSAKDSSL
                     GVSGSRYDTGRKIFENLLNSNQPTITMTITEGEKKKTITDLEKTSVLRAKEQHLQELF
                     QEFVLRYPEVQQVIEESYNRLYNRTVSRVYDGSHLVIDGLAQNISLRPHQENAIQRIV
                     EEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKFFPTK
                     KVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDKLNEL
                     REIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEAHHFK
                     NIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSISELYT
                     MMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLPELMK
                     IYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDMVKCGTVDPSQD
                     NMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMENKATQMIFSDI
                     GTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEVRILL
                     ASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYITKGS
                     FDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKYKMEL
                     ENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEMSKDQAFS
                     MTVGKQAFDQRSEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPINQPLPETF
                     SVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELKDKWTTAKVEI
                     EKNFPKEEDYQTKKSEYDVLAPLIETETDLDIIDQALRQFHEKGNEKQEQLSFELD"
     gene            7332..7616
                     /locus_tag="VGY43_001437"
     CDS             7332..7616
                     /locus_tag="VGY43_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302612.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEISLQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            7630..7926
                     /locus_tag="VGY43_001438"
     CDS             7630..7926
                     /locus_tag="VGY43_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302613.1"
                     /translation="MKDLLLIPVIFLAVGGILILLWRLFLIASGLFLIGFVSFLIFVE
                     AYGIYLFFTEPTLYFDDIRQHGLTSFTTVYLFINLMLVLGFSWRFINSKNKESM"
     gene            complement(7940..8137)
                     /locus_tag="VGY43_001439"
     CDS             complement(7940..8137)
                     /locus_tag="VGY43_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302614.1"
                     /translation="MKNLKEENLRRALFHIERHKQAINTSNNSEDNDFHKLLLQFSYE
                     VYERIKANKKPYPNLDSDKVF"
     gene            8297..8938
                     /locus_tag="VGY43_001440"
     CDS             8297..8938
                     /locus_tag="VGY43_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEQ4302615.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSIPSLPNTTTK"
     gene            8948..10033
                     /locus_tag="VGY43_001441"
     CDS             8948..10033
                     /locus_tag="VGY43_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HEQ4302616.1"
                     /translation="MEIEECKRISILDVANRLGISFKQISSSVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKEALAFLSEEPFQKEAVQEKRERPFYYPLKRT
                     EDSNCSLARYYLTECRGISEEIVQKMIQQGLIAQASWKTNETVEPVIVFKSFDHRHKL
                     QAASLQGIYKNPALSRERLKTILKGSHGHIGISFDIGKPNRLVFCESFIDLMSYYELH
                     QQSLTDVRLVSMEGLKRSVVAYQILRLITEENQKLEFLDTVTPSKLLPLINTIRNTTS
                     YFDNHPDLLTLAVDCDDAGKDFSDKLSQSGLPVLLDLPDNESGKEKVDWNDVLREKKS
                     DLQLMIETAKETLRNQPVRQTSQCLEL"
     gene            10084..10317
                     /locus_tag="VGY43_001442"
     CDS             10084..10317
                     /locus_tag="VGY43_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302617.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            10314..10697
                     /locus_tag="VGY43_001443"
     CDS             10314..10697
                     /locus_tag="VGY43_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEQ4302618.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            10735..11007
                     /locus_tag="VGY43_001444"
     CDS             10735..11007
                     /locus_tag="VGY43_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302619.1"
                     /translation="MFTKLFKKNQDNSDVFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     DQGSEQLKTEATYREETLDDTLKEAKNQLHKEQLEKNLERFRKNSQ"
     gene            11075..11551
                     /locus_tag="VGY43_001445"
     CDS             11075..11551
                     /locus_tag="VGY43_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4302620.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFAQIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            11551..12312
                     /locus_tag="VGY43_001446"
     CDS             11551..12312
                     /locus_tag="VGY43_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEQ4302621.1"
                     /translation="MDIQDYTDSAFKHALERNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKETAQHLKSKGYEVQLAIIATKPELSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEEIAIFERIQIYQRDRSCVYDSKENTA
                     PAADILQELLFGEWSQVEKEMLKVGEKRLNELLEK"
     gene            12340..>12895
                     /locus_tag="VGY43_001447"
     CDS             12340..>12895
                     /locus_tag="VGY43_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecF"
                     /protein_id="HEQ4302622.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAETII
                     KNGIEIVVVTDHNTTKGIKKLQKAVSIIMQTYPNYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISEKDGSY"
BASE COUNT         4540 a         1950 c         2587 g         3818 t
ORIGIN      
        1 tttttatgcg gataactaga tttttatgct atttttttct aaaaaaacag taagaaagcg
       61 taaaaaatca attcctgtac tagcgtgtaa ttgaaatttt ttagttttgg cgttagaact
      121 gtttcctcag tcctagcccc ttctcttttt gataagtatg cttggcagaa agtagtttgt
      181 aaatgattct gagaatctta tgagcataag caatgacggc cttcatcttg cttactcttt
      241 gggaaattcg attataaaaa aaagaaaaag ctggatcctt ggaatgtgct gcaattaatc
      301 ccgacatggt caaagcctgt tttatttagc gatttccttg cgtgatgtgt gaggattttt
      361 taatgccagc actataggct aaacatcttt ttctgtcatg agttagcagg ctctgcctga
      421 ttagagtttt acatgtaatc tattttaata gtaatgtttt atcattttca ggagaacgca
      481 gttttggctc gttctctttt ttgttgtgat acttctttca aggaatattt ggtaggattg
      541 gagtgaaaaa agattaacta ggaaagaagg aagtatatgg aagccattta tcaacgtgat
      601 tcggatcaag atggactaac tgatgctcaa gaattggcgc taggaaccaa tcctcttagc
      661 gcagattctg atggtgatgg acgttcagat ttagtggaag tagaagaagg aacaaatccc
      721 ttagaaaagg atttacaaaa cataaaccaa acaagtttaa ctgaaccatc ctcagtattt
      781 atggaaatga aacaaaagat ttcagatatg atggagagtc actacaagga atttatacag
      841 gctctgatta gtattgaaac agggattgaa aatcaacaag acctagaaga cttatatact
      901 tactacatga gaacagatac cgtttctctt ttgtctagtg atttagaaac cagtcctcaa
      961 gaggttgaaa tggagataga gttgtagggg aatcatgtga ttctcctatt ttcgtataga
     1021 tgaaaggagc gagtatggaa gtaatgcaat tattggctat gtttcgtgga acaattccaa
     1081 aagataggga gaaaatggac ctatttcttc gatatcaagc gcaacatttt gatgagaaat
     1141 ggcaggactt ggtagagagt tttttggctg aagagggtaa gatagaagag atacctcatg
     1201 tctattcgtt tcatcaagat attgtttctt tcctagaggc cagttctgaa aataatgacc
     1261 aagatttaga aagttacaca agaaattttg ggcaagcggg tctaggtaaa ttatctcaat
     1321 taagtaattt tgagaaaaac ttagttctgg aagtcgcaac ctataacctt tccactcgat
     1381 tttacatcca atctgaaaaa gaaaagctaa caccattaag tgagcttgta tgtcatcaga
     1441 atcaggaggt caatttagtc aatgtttatc gggttgcgaa taatctatct gaccgcatta
     1501 gtagagatat agaggaattt cttctaatgg ttgattccaa agaactagaa aaagaggttc
     1561 ttgagattca ttttgaagaa aaagagggag atgttctagc ctatttgggt tcagaattga
     1621 tggctacttt agataccgtt acggatcttg tccattatga aggaaactac caacaactac
     1681 cactgacaca aaagctgaag attattactc attttgatga tgtaaaggct agaagcgaaa
     1741 aatctaagca agtagaggaa gcggtcttac ctttagataa tattgaccag gtagaagaaa
     1801 atgtggaagt tcattcccta tctaaagtag ataaaattgt agaagaagct ttgagggaat
     1861 atccaatcgg ttcacaagta agttataaag gtcaagtatt tcagttggtt tcgattgaaa
     1921 atgcccagtt aaatgactta gttcgcctag agctattcaa tgattccaac cagttatttg
     1981 aagaaaatcc tatcttatac ttgaacagtt tggaagagat tgaacaagta ttgtctcttg
     2041 tagaacttga aaaagaagat tcagagattg agattgattc atcaagtgaa agtcaggaaa
     2101 tagatttgtt ttcctatctg gaagaagaaa atgaaaagga taaggaaaca gaaactctta
     2161 tttcaagtat agaagagttg gatatccctg ttcaagattt cgtttttcca gatgatttag
     2221 aggactttta ccctaagaca aatcgagaaa aaattgaaac gaatatcgct gcaattgacc
     2281 ttgttaaaag attagaaaaa gagggacgac aagcgaatcc agaagaacaa gaactactag
     2341 ctaagtatgt tggatggggt ggtcttgcca atgaattttt cgatgaactc aatccaaagt
     2401 atgaagcaga acgtttaact cttaagagtt tagtaagtaa atcagaatac tcgaccatga
     2461 aacaaagttc tctcacagcc tattatacag acccaatgat tattcgccag atttggcaaa
     2521 aattactgga tgatggtttt gagggaggaa ggatattaga tccttctatg gggactggga
     2581 acttctttgc ggctatgcct agaagtatac gagataaatc agaactctat ggggttgaat
     2641 tagacagtgt gacaggcgaa atcgcaaaac aactccatcc aaatgtccac attgaagtgc
     2701 gaggatttga agaagttccc tatcaaaata atagttttga tttagtctta acgaatgttc
     2761 catttggaaa ttttcgcatt gccgataaaa actatgataa accttatatg attcatgatt
     2821 actttgtcaa acactcactt gatttagtaa gagacggagg acaagtgtcg attatctcat
     2881 ctatcgggac aatggataag cggacagata atgtcttaca agagattaaa accaacactc
     2941 attttttagg gggagttcgt ttgccggata cggcttttaa aaagattgca ggtactcgag
     3001 tgaccacaga tctcctcttc tttcaaaaga atcaagcaaa gaatcttaat gaagaggaac
     3061 ttgtttttag tggttctatt ccctttgagg aggataagcg tgtctggatc aatccttatt
     3121 ttgatgggaa atacaataca caagttttgg gtgaatatga agtacgtaat tttaatggag
     3181 gaaccctcaa tgttaagggg gaatcagaaa cattagctac tgaaataatg aaagcattcg
     3241 agaatgtgga agcacctaaa caaattgaca attctttgaa agcacctgtt tttatccaag
     3301 aagaagtgga taattctatc ccaagtcgta tacgtgagga cttagcgctc tattcttttg
     3361 gatatgaggg aaatcaaatt tattaccgag atacgcatgg cattcggaaa agttcaaaag
     3421 tagacgaaat tagttattat gtagatgaga agggagattt taaagcttgg gacagttctt
     3481 tgtctgaaca taaaatagac cgattcgtgc aacttcattt gacagatgag gaagcactag
     3541 atgtttacaa gtcagaagaa gcgagtaaaa gagggaaata taagggactg ttcaaaaaaa
     3601 ctgtctttta tgaaagtccc ttatcggata aggacattag tcgcattaag ggcatggttg
     3661 atttgagaga gacctatcaa tccttaattg aaattcaacg tcatccagat tatagtcggg
     3721 ctgattttca ggtgttactt agtaaactca atcatgacta tgatcgcttt gtaagtcaat
     3781 ttggatactt gaatgcctca gtcaatcgga acttatttga tagtgacgat aagtattctt
     3841 tactagcaag tttagaagat gaatacattg attctaaaag tcagaaagta aaatataaaa
     3901 aatctttagc ctttgagaaa gcattggtta ggccagagag agtgattgca agagtttcaa
     3961 cggctctaga tgccttaaac tctagtttat cggatggtag aggggttgat ttagactata
     4021 tggtatcaat ttatcctgaa catagccaag ctgctatttt agatgagttg ggtgaccaga
     4081 ttttaataga tccagaaagc tatttaagag gggaaagaaa atatctttct aagaaccagt
     4141 ttttatcagg agacattctc aataagatag aagtagttca actattagtg gaggaaaaca
     4201 accaagaata tgattggagc catgctttag atttattaga atctgttcgc cctccaagga
     4261 ttcatcttgc agatattgag tttaaaatag ggtcacgttg gattcctcaa tccgtttatg
     4321 gtaaatttgc ctttgaatgt tttaccaatc gtgaatttga attgtcttcg ccagatgttg
     4381 aacaagtcat tgaagtgaat catgttgatg ggcaggttca tttaaggaca tcatttgctt
     4441 atcgctatcc aagtgccaaa gatagtagtc ttggagttag tgggtcacgt tatgatacag
     4501 gaagaaagat ttttgagaat ttacttaatt cgaaccaacc gacgattact atgactatta
     4561 cggaaggaga aaagaaaaag accatcacag atttggaaaa aacctctgtt ctaagagcaa
     4621 aagagcagca tttacaagag ctctttcaag aatttgtctt acggtatcca gaagtccaac
     4681 aagtcattga ggaaagctat aatcgtcttt ataatcggac ggttagtcga gtgtatgacg
     4741 gtagccatct agtcattgat ggcttggcac aaaacatcag ccttcgccct caccaagaga
     4801 atgccattca aagaatcgta gaagaaaaaa gagccttgtt agctcatgag gtaggttcag
     4861 gaaagacctt gaccatgctt ggtgctgggt ttaaattaaa ggagttgggg atggttcata
     4921 agcccttgta tgtagtacct tctagtttgt ctgctcaatt tggtcaagaa atcatgaaat
     4981 ttttccctac taaaaaggtc tttgtgacca ctaagaaaga ttttgtgaag gcgagaagaa
     5041 aacaatttgt atcacgtatt attacaggag attacgatgc tattgtcatt ggggattctc
     5101 aatttgaaaa aatccctgtc agtaaggaaa gacagatgaa ctatatcgag gataaactta
     5161 atgaactacg agagattaaa acacattctg aaaataagta tactgttaaa gaagcagagc
     5221 aatcaataag tggtctagag aaacaattgg aagaactgca acgctttaat cgtgatagtt
     5281 ttattgattt tgagaactta ggaattgatt ttctctttgt ggatgaagca catcacttta
     5341 aaaatattcg tccaattact ggacttggga atgtagcagg gattactaat acaacttcta
     5401 agaagaatgt ggatatggaa atgaaggttc gacagattca ggaagaacat gattttaaaa
     5461 atattgtctt tgcgacagga acacctgttt ccaattctat tagtgagtta tatactatga
     5521 tgaactatat tcaacccgat atcttaaaac gctatcaagt tgattatttt gactcttggg
     5581 taggtgcttt tggagaaatt caaaactcta tggaattagc tcctacaggg gataagtatc
     5641 agcctaagaa acgatttaaa aagtttgtca atctacctga gttgatgaaa atctataaag
     5701 aaacagctga cattcaaaca caagatatgt tggatttacc tgttccagaa gcccatatta
     5761 tccctattga gagtgagtta actgaaaacc agaaactcta tttagaagaa ttagttatga
     5821 ggtcagatat ggtcaaatgt ggaacagttg atccgagtca ggataacatg ttaaagataa
     5881 caggtgaggc acggaaacta gctattgata tgcgtttatt ggactctagt tatagtctag
     5941 cagacaatca taaactgctt caggtagtgg ataatgttga aagaatttat cgtgagggaa
     6001 tggaaaataa ggctactcag atgatttttt cagatattgg cacacctaag aaaaaggata
     6061 atggctttga tgtttattct gaaataaagg ctttattagt tgatagagga atccctagta
     6121 aggaaattgc ctttgtacat gatgccaata gtgatgaaaa gaagaatagc ttgtctcgaa
     6181 aggtcaatgc aggagaggtg cggattcttc ttgcctcaac tgaaaaagga ggaacaggtt
     6241 taaatgttca gagcaagatg aaagcagttc atcacctgga tgtaccgtgg agaccaagtg
     6301 acattcagca acgcaatgga cgtattatcc gacagggaaa tgaaaacaag gaagtggata
     6361 tttaccacta cattaccaaa ggttcatttg ataattatct atgggcaact caggagaaca
     6421 aactccgtta tattaagcag attatgactt ctaaggagcc gattcgtgct gcagaagaca
     6481 ttgatgagca gaccatgaca gcttctgatt ttaaggcact agcaacaggt aatccttatc
     6541 tcaaatataa gatggaacta gagaatgatc taactctatt agaaaatcaa agacgcgcct
     6601 ttcaacgtag caaggatcac tatcgtcata caatctctta ctgtgaagaa aatatgccta
     6661 ttcttgagaa acgattaagc aaatatgaag gagacattca acagtctgaa atgtcgaaag
     6721 accaggcatt ttctatgacg gtaggtaagc aagcttttga tcaacgatct gaagcagggg
     6781 aatccctaca ccgtcttatc cgtcataatc aagctgacag caaagaattc cgtaccctag
     6841 caagctatag aggatttgac attaaaatgc ttagtcttcc aataaatcaa cctcttcctg
     6901 aaaccttctc tgttaagatt gtaggagaaa atcagtattc tgtcagttta gatttgtatt
     6961 ctcctttggg gacaattcaa aggcttcagc atacgattga tcacatcaag gaggaccaag
     7021 tgaaaactca gaacttattg gatgaattaa aggataaatg gactactgct aaggtagaaa
     7081 ttgagaaaaa ttttccaaag gaagaagatt atcaaactaa aaagtccgaa tacgatgtac
     7141 tcgcgccatt gattgaaaca gaaacggatt tagatattat tgatcaagcc ttaagacaat
     7201 tccacgaaaa aggaaacgaa aagcaggaac aactttcttt tgaattagat taaaaaaaat
     7261 atataaatag cggacaagaa aagaaaagcg cggtagaata aagatagaaa gaaagaaacg
     7321 aggtaacaat tatgatggaa gatacctatt atcaattaga agaggctttg gtacagggat
     7381 ttcaaacacc tgaagaatac caagcctaca aggaactaaa ggaacattat gaggaagtga
     7441 cgggggatta cagtttttct aaacgagaac tcactagtca attggaaatc tctcttcaga
     7501 atcatcgagg tgtggacttt gaagaacatg aaaaagaaga gtatttggac ttagttcaaa
     7561 aattagaaga gtttgattcc tctcttgcca cccattatcg tcaactgatt gactagaaag
     7621 gagaaagtca tgaaagattt actccttatc ccagtaattt ttttagcagt aggaggaatt
     7681 ctcattcttt tatggagact ctttcttatt gccagtggac ttttccttat tggttttgtc
     7741 agttttctta ttttcgtgga ggcctatgga atttatttgt tctttactga accgacttta
     7801 tactttgatg atatcagaca acatggttta actagtttta cgactgtgta ccttttcatc
     7861 aatctaatgt tggttctagg attcagttgg cgtttcataa actccaaaaa taaggaaagt
     7921 atgtaaactt gttagatagt taaaaaactt tatctgaatc taaattcgga taaggttttt
     7981 tattagcctt gattctttca tacacttcat agctaaattg gagcagtaat ttatgaaaat
     8041 cattatcctc actgttatta cttgtattta tggcttgttt atgtcgttca atatgaaaaa
     8101 gagctcttct caaattttct tcttttaaat ttttcatagt tacattataa gctgaagaca
     8161 gatagttttg atatttttct ctgaactgta cgattttgcg cctgaaatgt aggaattacc
     8221 tttcgttgtg atgtgataaa acttacaagt tctttttgtt attcttgacc tagtttttat
     8281 agaaagaagg tctaagatgt taaataaagt caaaactaaa gccttaatta gtgttggagc
     8341 agtagccgca actagcttta ttctcatgat gggatatact gctggtcaac actcgactgc
     8401 taaacaaagt cgtaaagaga ttgaattggc tgcagctaaa cttgtagagg acaaacaagc
     8461 agaagataaa gcaagtattt tgtcatcgga tactgtaaaa gaatttttga ctcagtacta
     8521 tacgaaagaa aagctcggag aaaataatac acgtattcaa ccttatatga ctgaatcggc
     8581 ttattctcaa gaattgtcaa gtcaaaatga tgccatgaac caagtgtata aggattatat
     8641 tttagattat cattttgaaa aagcagatat ctttgtcaat cagactacga atcaagccat
     8701 tgccatggtc tcttataatg taacctatgt atccgattta aagaatgcca accaatcaaa
     8761 gaccaatcag acagaaacaa gaacagttaa gttatcctat tctaaactac ctggtaagtt
     8821 attggtcaac caagtacagg tttggaaatc tgggttagat gatttagata aggcaactcc
     8881 taaaacttta gaagaatcat catctattcc atcactgcca aatactacga caaaatgatg
     8941 atgttgcatg gaaatagaag aatgtaagcg aatttcaatt cttgatgtag ccaatcgttt
     9001 aggtatctcc tttaaacaaa tttctagcag tgtctatgaa catcctgaac acgattcatt
     9061 tcggattttt tcaactacta atacttttaa atggttttca agagatattc aaggtgatgt
     9121 cattgatttt gttcgacttg ttaagggaat ttcctttaaa gaagctctag cctttctttc
     9181 tgaagaacct tttcaaaaag aagctgttca agaaaaaaga gagagaccat tttattatcc
     9241 tttaaaaaga acagaagatt ctaactgtag tctggccaga tattatttaa cagaatgtag
     9301 aggaatctca gaagaaatcg tacaaaagat gattcaacaa ggtttgatag cacaagccag
     9361 ttggaaaaca aatgaaactg ttgaacctgt tattgttttt aaaagctttg atcatcgtca
     9421 taagctgcag gcagcaagcc tacaagggat ttataagaat cccgctcttt ctagagagag
     9481 gttaaaaacg attctaaaag gaagccatgg acatattgga atatcttttg atattggtaa
     9541 acccaataga ctagtctttt gtgaatcgtt tatcgacttg atgagctatt acgaacttca
     9601 tcaacaaagt ctaactgatg ttcgtttggt atctatggag ggattaaaaa ggtctgttgt
     9661 ggcttatcaa attttacgac tgataactga agaaaatcag aagttggaat ttttagatac
     9721 agtaacacct tcaaagttat tgcctttgat caatacaatt cgtaatacca ccagctattt
     9781 tgataatcat cctgatttat tgacactcgc ggtagattgt gatgatgcag gaaaagattt
     9841 ttccgataag ttatctcaat caggattgcc tgttttactg gatttacctg ataatgaatc
     9901 agggaaagaa aaagtagact ggaatgatgt ccttagagaa aagaagtcag atttacaatt
     9961 gatgatcgag actgcaaaag agacattgag gaatcaacca gtaagacaaa cctctcaatg
    10021 tttagaattg tgataacaaa atcaagatgt tttagctaat attagaatga aggaggatcg
    10081 tatatgacca ttattgaacg cttagaagaa aaggtcacta ggcaagaaag caaggtagca
    10141 agagagacag aaaaactcgc tgcttacaaa gagcaactgg agacagcgat gtttgcgacg
    10201 ttcaaaaggc gtcaaagcat tagtcacatg agttttgaag aagctcttga ccatgccttt
    10261 ggtaaagaaa gacaattcga tgattctgaa tttagaaagg atgaaatgag tgaatgacaa
    10321 aagattggaa ttttaatcaa ccattagaaa gtaaatcaga aaatcaagaa gatccagata
    10381 aaattgcggc cttatttgga aatcatcaag gaggtaatga tgtaaattat gaagcagctt
    10441 ttcaaaagcg caaacaagca cctgtgacgg aatcaaattc tagttctaaa cccaaagtta
    10501 cagaggttag aacaggaaaa gagacagata tcactacaag ttatcagcaa catcttaaaa
    10561 gacttattgc agataacaat agcgatattc aaagtagtca aaagaaaatt gaagagctac
    10621 atacgttgat cgacacaaag aataaagaca ataagaaatt gcagtcaatt tatgatgcga
    10681 tttccgaatt acactaagca gtcctgatag gctgcttttt ttgagaggtt atagatgttt
    10741 acaaaacttt ttaagaaaaa ccaagacaat agtgatgtat ttaagaagct aattcataga
    10801 ctatctgata tgtctgtaca agatcttgaa aaaatagacc gactgttaga tatcattttc
    10861 actccagatc aaggatcaga acaactaaaa acagaagcaa cttacagaga agaaactttg
    10921 gacgacacat taaaggaagc taagaatcaa cttcataagg aacaattgga gaagaattta
    10981 gagagattta ggaaaaatag tcaataacgc accaaaattg gtgcgttctg cttttttatg
    11041 ctataattga attataaaaa taaaggagtt tgccatgatt ggaaagaaca taaaatcctt
    11101 acgtaaaaca cacgacttaa cacaacccga atttgcccaa attataggaa tttctcgaaa
    11161 tagcttgagt cgttatgaaa atggaactag ttcagtctct acggagctaa tagacatcat
    11221 ttgtcaaaag tttaatgtat cttatgtcga tattgtagga gaagacaaaa tgcttaatcc
    11281 tgttgaagat tatgaactga ctttaaaaat tgaaatagtg aaagaaagag gtgctaatct
    11341 attatctcga ctttatcgtt atcaagatag tcagggaatt agcattgatg atgaatctaa
    11401 tccttggatt ttaatgagtg atgatctatc tgacttgatt catacgaata tctatttagt
    11461 tgaaactttt gatgaaatag agagatatag cggctatttg gatggaattg agcgcatgtt
    11521 agagatatct gaaaaacgga tggtagccta atggatatcc aagattatac tgatagtgca
    11581 tttaaacatg ctttagagcg aaaccttcgc tcactgacaa gaggaaaaaa gtccagtaaa
    11641 caacctatag cgattttgct tggagggcaa agtggtgctg gtaagactac aattcatcga
    11701 attaaacaga aagaatttca aggaaatatt gttatcatag atggcgatag ttttcgttct
    11761 cagcacccac actatttaga actgcagcaa gaatatggca aagatagcgt tgaatacacc
    11821 aaagattttg cgggaaaaat ggtagagtct ctagtaaccg aattgagtca tttgggatac
    11881 aatcttttga tagagggaac tttacgaaca attgatgttc caaaggaaac agcacaacac
    11941 ttgaaaagta agggatatga agtacaatta gccataatcg caacaaagcc cgaattgtcc
    12001 tatctgagca cccttatccg atacgaagaa ttgtacgcta tcaatccaaa tcaagcacgc
    12061 gcaactccaa aagaacatca tgatttcatt gtaaatcatc tagttgataa tacacgacaa
    12121 ttggaagaaa tagctatctt tgaaagaatt caaatttatc aacgagatag aagttgtgta
    12181 tatgattcaa aagaaaatac agctccagca gcagatattc ttcaagagtt actgtttggg
    12241 gagtggagtc aggtagagaa agagatgttg aaggtggggg aaaagagact taatgaatta
    12301 cttgaaaaat aaacaattta tatttttagg agagtagaag tgagagggtt taataacaag
    12361 ataaagtctg tttatcaaga actaacaaat tccaaagaga aattcggtag ctttcacaag
    12421 actttaattc atttgcatac acctgtttct tatgattaca agctattttc taattggact
    12481 gcaacgaaat atagaaaaat tactgaagat gaactatatg atatattttt tgaaaataag
    12541 aaaataaaag ttgataagac aatttttttt agtaattttg ataaggttgt tttttctagt
    12601 tcaaaagaat atattagttt tcttatgtta gcagagacaa tcataaaaaa tggaatagaa
    12661 atagttgtag taactgatca taatactacc aaaggtatta aaaagttgca aaaggcagtc
    12721 tcaatcataa tgcaaactta tccgaattat gatatacatc ctcatatttt acatggagta
    12781 gaaattagtg cagcggataa attgcatatt gtatgtatat atgattatga acaagagtca
    12841 tgggttaatc aatggttaag tgaaaatatt ataagtgaga aagatggaag ttatc
//
LOCUS       DAUCXI010000043        12504 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.043, whole genome shotgun sequence.
ACCESSION   DAUCXI010000043 DAUCXI010000000
VERSION     DAUCXI010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12504
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.043"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..1121)
                     /locus_tag="VGY43_001448"
     CDS             complement(<1..1121)
                     /locus_tag="VGY43_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEQ4302623.1"
                     /translation="MPSMKHILKSLSILLVGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVRISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKIVNSISDLQSSLYGH"
     gene            1333..1812
                     /gene="rlmH"
                     /locus_tag="VGY43_001449"
     CDS             1333..1812
                     /gene="rlmH"
                     /locus_tag="VGY43_001449"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEQ4302624.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYST
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK"
     gene            complement(1969..2042)
                     /locus_tag="VGY43_001450"
     tRNA            complement(1969..2042)
                     /locus_tag="VGY43_001450"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2006..2008),aa:Arg,seq:tct)
     gene            2228..3320
                     /locus_tag="VGY43_001451"
                     /pseudo
     CDS             2228..3320
                     /locus_tag="VGY43_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185110.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            3299..3370
                     /locus_tag="VGY43_001452"
     tRNA            3299..3370
                     /locus_tag="VGY43_001452"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3332..3334,aa:Glu,seq:ttc)
     gene            3404..3477
                     /locus_tag="VGY43_001453"
     tRNA            3404..3477
                     /locus_tag="VGY43_001453"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3438..3440,aa:Asn,seq:gtt)
     gene            complement(3974..6550)
                     /locus_tag="VGY43_001454"
     CDS             complement(3974..6550)
                     /locus_tag="VGY43_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEQ4302625.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMGIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLASMP
                     DAIYLFTLIKFGVIGLAACYSFHRLYPKISAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVVLGLNKLITENKTRTYYLSISLLFIQNYYFGYMVALFCILYALVCLLSLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPVKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPSTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFSSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPLNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNINTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYISIPNIIF
                     SNPDAKEVRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLLYKYIDIKSK
                     LL"
     gene            complement(6633..8252)
                     /locus_tag="VGY43_001455"
     CDS             complement(6633..8252)
                     /locus_tag="VGY43_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEQ4302626.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            complement(8331..9203)
                     /locus_tag="VGY43_001456"
     CDS             complement(8331..9203)
                     /locus_tag="VGY43_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEQ4302627.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     misc_binding    9326..9567
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9622..10644
                     /gene="trpS"
                     /locus_tag="VGY43_001457"
     CDS             9622..10644
                     /gene="trpS"
                     /locus_tag="VGY43_001457"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEQ4302628.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
     gene            10952..12433
                     /gene="guaB"
                     /locus_tag="VGY43_001458"
     CDS             10952..12433
                     /gene="guaB"
                     /locus_tag="VGY43_001458"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEQ4302629.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
BASE COUNT         4207 a         2089 c         2314 g         3894 t
ORIGIN      
        1 tcgtgtccgt atagactact ttgtaaatca ctaattgaat taactatttt gccatcaatt
       61 tctgtaatca catcgtactg agcaagtttg ccagatgccg gcattccttc cttaacttct
      121 gctactacaa taccaccagt tacactagtt ggaatattaa tttggctaag agcatttgtg
      181 gataagtcat ttaaattgac catggatatt ccaagagcag gtctgataac ttcaccatta
      241 gtttctagtt gtttaataat tttaataaca tcagtagatg ggatagcaaa accaattcct
      301 tcaacagcac cactattacc gttgctacca gttggggtag aagaaatttt acttgaatta
      361 attccgatta cttgcccctc aatattaatt agtggtccac cagagtttcc agggttaata
      421 gcagcatctg tctgaatagc atttgttgag acagtctcac cattctcgtt ttttaaagtt
      481 acagtacgac ttaaactaga gacgattcct tgagtaacag aattagcgta ttgtgttcct
      541 agtgggctgc cgatagcaat agcaacttct ccaacattta gttttgtaga atctgcaaat
      601 tcagctactg tttttatctt atctgaagag atcctaacaa cagctaaatc cgaataagta
      661 tcagctccaa ctaattcacc aacaacttta gatccgtctg ccataagaat ttcaatccgt
      721 ttagctccgt cgataacatg gttattagta acaacgtaag cggagttgcc atcttttcga
      781 taaatgaccc cagatccttc actaaaaata gataattcag catccttatt ctcttttgaa
      841 cgcccttctc caaagagttt tgtataaggg ttagaaaggg atgaagaagg gttatcttga
      901 taattaataa ctgatacaac tgcattttga acagctttga cagctttagt agtattggtt
      961 gtgttgttaa aaaccatatt actagttgtt gccttacctg aatttatttt tgaaggagaa
     1021 tgtgggtaga gattattaaa tgtaataatt gctattaatc ctcctaaaaa tccaactagt
     1081 aaaatactta aggattttaa gatatgtttc atacttggca tgttttgtcc tccgaattat
     1141 ttgtccatag cttatagaac tttgcttaat tataccttaa aaataaaaaa aagaaaagta
     1201 atccacaggc tgtggattac ttttcttttt actaataaag acctttgtac aaaggttttt
     1261 attagtagtt gaagaaaaat aacttgtgga taaattgtgt aaaaagtaat gttcttgtga
     1321 tacaattaag ctatgaaagt aaaactaatt tgtgttggaa aactaaaaga aagatacctc
     1381 aaagatggta tttcagaata tcaaaaaaga ctttcccgtt tttgtcaatt cgaaatgatt
     1441 gagttaactg atgaaagaac accagataaa gcaagttttg ctgataatca attgattatg
     1501 agtaaagaag ctcagcgaat ccataaaaaa attggggaac gtgattttgt aattgcatta
     1561 gctattgaag gaaaacagtt tccttcagag acatttagtg aattaatatc aggggttact
     1621 gttaagggat attcaactat cacgtttatt attggtggaa gtcttgggtt agattcaatt
     1681 attaaaaaaa gagctaatat gctaatgagt tttggattgt taaccttacc tcatcagtta
     1741 atgcgtctag ttcttactga gcaaatttat cgtgctttta tgattacaca aggcagtcct
     1801 tatcataagt aagagagtgt gaactggaat aactaactct taccacttta ttagataata
     1861 gttcggtata attaaaagca aacattaaaa aaagacagac taaatcctat cttttcaata
     1921 cactaaggta aatacaaaaa aagcactaaa acagtgcttt tttatctttg atcccagcag
     1981 gattcgaacc tgcgaccgtt cgcttagaag gcgaatgctc tatccagctg agctatgaga
     2041 ccttaaccac atcattttaa caaaaattat ctaaaactgt caatatttat tttgaaaaaa
     2101 ctagaaaata acattatatc ccgcgttgaa aaattctaaa atgaacttag ccacttttaa
     2161 ggtatgaaaa aagcacctct aagaggtata cttgtagttc accacaaaca caaggaaact
     2221 caaaaagatg caagattatt atacaccaaa aggcaaacaa ttgacaatcc atgagcgtcg
     2281 gcaaattcaa cgctggaagc tctaatcgtg aaattgctcg cttactaggt aaggcccccc
     2341 agaccattca taatgaaatc aagcgaggat tggttaggca acaggttcgt aaaggaaagt
     2401 ttgaagccgt ttattctgct caacatgctc agttggtcta tcaagaaaat cgcaagcgtt
     2461 ctgttagacc cattagacag cgtaagcaag atagggaggc tattgaacac tacatgcgtc
     2521 agaactattc ccctgagatg atagttaaag ctaagggagt tcaagtccct gtatctacca
     2581 tctattactg gattcatcat gggaaattaa gtcttggtaa ggaggctatg ctttatccga
     2641 gaaaggctaa gcaggctaga aaacatgcca gtccttattt taaacccgca ggaaagagta
     2701 ttgaacaacg cccagatagc attaaccaac gtcttgaagc tgggcattat gagattgata
     2761 cagtcattct gacgagggct aaaaatcaat gcttactcac cctaacggac aggaaaacac
     2821 gtcatcagct gattcgatta ataccggata agtctgctca agctgtcaat aaagctctta
     2881 cggggattct aaaagactac accgtcaact ctatcacggc agacaacggg acagaatttt
     2941 ctcgcttatc agatgtcttt ccagcaagtg acatctacta tgcccatccc tatgcgtcat
     3001 gggagagagg cactaacgaa aaccataatc gcctgattcg cagatgtctc cctaaaggta
     3061 ccaaaacaac gacccctaaa gaagtcgctg ctattgaaca ttggatcaat cattatccta
     3121 aacgactctt caactataag tcgccagtag aaatgttaaa actggctaac ttcaacttga
     3181 aatttggcga caacttgcgg tttaaaaaaa atcaaatttt ttttaaaaaa agtatagaca
     3241 aaaaaaatca atctgctata atagtaagag tgttaaggag atatcctcca aaacttctgg
     3301 tccgttggtc aaggggttaa gacaccgcct tttcacggcg gtaacacggg ttcgaatccc
     3361 gtacggacta tcgcaattgt cattttggca atttttttct ttttccggca tagctcagtt
     3421 ggtagtagcg catgactgtt aatcatgatg tcgtaggttc gagtcctact gccggagtga
     3481 taagatattt cctaagataa tcttaggatt tttttattta gtaaaacaga tactcaggtc
     3541 aaatactcaa tttactaatt attaaaccac taaatacagc attgtgaact aacaggattg
     3601 tattttgcat taaaatagaa gttctgttct ttaattgtat agatgataac attaagttta
     3661 attacaaaca ttaactgaag cttaattttt tacattttga aagcatgtct cccatttaat
     3721 actgatgaat ataagattat tgtaaggagt caaaagattg aaatcgtatc agcgatgatt
     3781 attgtcattt caatctttga aagagagtag tttaacatta accctcacga aaaatctgac
     3841 ctttatatta tttgagttta ttagtaaaat cgataaaagc atctcaagta ttagaatatt
     3901 tgtctagctc ttgagatgct tttagtatat tgactcattt gccaaattga taaaaaaatc
     3961 tgattttttt ggactaaagt aatttagact ttatatctat gtacttatac aaaagcatat
     4021 aagcgataat tcctacgcaa gatagagata accctaattt aaaaccatta ggaataaagg
     4081 taaggataac acgtcccttt cctttaggaa tagtcactga tagaaatcct ccttgtgctt
     4141 ttttgactgg aagatttttc ccatcttttt gtgctgacca acctttatcg taaggaagtg
     4201 taaaaataag agaacctttc gtttttgaat tataatcagt gattaccgta ttacttttag
     4261 cgtaagtatg aacatttttt tgtttaatac tattcattgc ttcaaggtaa gattcaatag
     4321 acaaactata aaaatgaggt tccttaaaac taatttgttt attttttgga aaaacaaacg
     4381 aaaatgtagc aactttggca tcggcgaaat atcctaaatc aaaaaaagag taagcgttat
     4441 ctgtagtata tatgaaatta tgattatctg tctgaatacg cacctcttta gcatcaggat
     4501 ttgaaaatat aatattgggt atgctaatat agagttgact atgtttaggg atgttaattt
     4561 gataattaag ggtaacggag ttttgataat cagaagcttg tgcagatatt tgtccgttaa
     4621 attgattagc accagaaata agttgagctg gctgtaagtt aaaataggtt aaagatttcc
     4681 cacttagttg gttaagtaat ttggtttggt tatcaagggt attgatattt aggttgacat
     4741 ctttgtaaac attacgtgtt aatatagcta aagggctact atagtgattt tgataaagag
     4801 tagtattccc gctagttttt agttttgtaa atccaaattt atttagaggt ccttcgctaa
     4861 gattatattt tataccaagt agactgtcca taataatagt attgttttgg tatctaaggt
     4921 ttaaatttgt gcctttagac tgaaatccca atcgatccaa taaagaacta gatagtctat
     4981 ttcttacaga ggaaaattgt gaaatgccgt aataattaaa tttcatgcta tcgttccctg
     5041 tttggggaag tagtctttcc attctaaaaa aaggttgact attttttgac acagagttga
     5101 caaggttgtt aatatccttt aattgactat tatatatctg tcgtgatgag aatccccact
     5161 ccttattaat tccttgaagc tggtagtagg tgtttaaccc tgattcaaga aggctaaaga
     5221 taagtatgaa agcagaaata aaagtagatg ggatttgaga atttctaaac gaaaatagtg
     5281 aaatagtata acctaataat aaaaaaacac taagtaaaaa aagagttaaa ggtagaaaat
     5341 tatattgttg agaaaagcta taaggaagag atgtcagtat aatgaggaaa ataaaagcaa
     5401 aacctgcttt tatttgagtc acttctttta gtcgagagag agtctcacat gcgagtaata
     5461 ggataactat ggaaaaagac caagcgtagc gatgcaaaaa catatttggt gagtgcatcc
     5521 cctgccaaaa aagatcaagt ggctgtaggt aaaaacttat tataataaaa gttaacaagc
     5581 aggcattggc taattttatt tttaaaggga tactttctaa agtaaaataa ataacactaa
     5641 gcattagggg aaataatcct acgtaaatca taggcagagc attaaacttg gtagtatcgt
     5701 acactcctat tgagagctta gcaggtatat ccaaaaacca agcattgttc gtaactaact
     5761 gttttaccgg ggatagattc tctccataag ttgacaaatc tagataggta ggaagtatta
     5821 ctagagcact tgttaaagca gcacatattg acacagctgt aaacctaaca aaagcgataa
     5881 acattttgtt aaaatcattg agacttaaaa gacaaactaa ggcgtaaaga atacaaaaaa
     5941 gagcaaccat gtagccaaag tagtaatttt gaatgaataa taatgatatc gaaagataat
     6001 aagttctggt tttattttct gtgataagtt tatttaatcc aagtacaaca agtggaagaa
     6061 gaatgaaaac atctaaccaa gaatttagtt ccatttgact tgtcaagaag ctcattaagc
     6121 tataaaaaac tgagatggaa atcatcaaga aagcactgat ttttggatat aatctatgaa
     6181 aagaatagca tgcagctaat cctattaccc caaattttat caaggtaaac aaatagatag
     6241 catctggcat agaggctaaa ttaaaaaaga aaagtaatgg agaaaagaaa ctgccaagat
     6301 aataacacat taaagcataa aaatttatcc ctagtccgct tgtaaaggta taaaaaaaac
     6361 tatcagaacc gtgcatgatg ttacgaaagt tctgcgcaaa aataacatac tgatgaaaag
     6421 catcactagc tagaattgtt ttatcactat tataataaat gcccatcgat agaaggatga
     6481 taaatataat actaagaggg aacaaaaaac tagcaagtcc agcaattatc catttattat
     6541 tatttttcat aaattatatg gtctttcgtt tacaaatttt aaaaaagagg ctaggaagag
     6601 atcttcttag ccacctcatt tatcataagg ttttatttcc aaagttcagc aactcgggct
     6661 tggacttctg gattgtcaag gaattcgtca taagtttcat ctatacggtc gataacacca
     6721 ttttttgaaa taacaacgat gtggttagca atcgtttgaa taaattcatg gtcatgactg
     6781 gcaaagataa cagattcttt gaagtctttg atcccatcat taagacttga aatagattcc
     6841 aaatccaagt gatttgttgg atcatcaaga ataagaacgt ttgatttcaa tagcatcaac
     6901 ttagaaagca tgacacgcac tttttcgcca ccggaaagaa cgttaacaga ttttttaact
     6961 tcgtctccag agaaaagcat ccgtcctagg aaaccacgta aaaaagtatc gtcatcttca
     7021 ccttttgagg caaattgacg taaccattca agaatagatt cttccgtggc aaaatctttt
     7081 gaattgtctt taggcaagta agaacgactt gttgtcactc cccatttaat ggttccttcg
     7141 tagtcaatat catctgctaa agcacgcata agagcggttg tttgaatatc attttgacca
     7201 ataatagcag ctttgtcacc tggacgtaaa atgaaactga tattatcaat gattttctct
     7261 ccatcgatcg ttacagaaag attttcaaca gtgaggaagt cattccccat ttcacgctct
     7321 gctttaaaat taataaatgg gtatttacgg cttgagggaa caatttcttc taattcaatc
     7381 ttatcaagca tttttttacg agaggttgct tgttttgatt tagatgcgtt tgctgagaaa
     7441 cgggcaacga attcttgtaa ttctttgatt ttttcttcgg ctttagcatt gcggtcagct
     7501 tgtaaacgag cggctagctc agaagattgt ttccagaaat cgtagttacc cacaaagagt
     7561 ttgattttac caaagtcaag gtcggccatg tgagtacata ctttattcaa gaagtgacgg
     7621 tcatgggaaa caacgatgac tgtattttca aaatcaatca agaaatcttc caaccatgaa
     7681 atagattgaa tatcaagacc attggttggc tcgtcaagta ataaaacgtc aggcttacca
     7741 aagagcgctt tagcaagaag gactttcact ttatctccat tagccagttc actcatattt
     7801 tggtagtgaa ggtcttctgg aatatttaga ttttggagaa gttgagaagc ttcactttct
     7861 gcctcccagc cacctaattc agcaaagata ccttctagct cagcggcacg aaccccatct
     7921 tcttctgaaa aatctgcttt catatagata gcgtcttttt ctttcatgat attgtaaagt
     7981 tgctcattac ccatgattac aacatcaatc gcacgttctt cttcataatc aaaatgattt
     8041 tggcgaagaa cagataagcg ttcgtcaggt cctaaagaga tatgaccagt acttggttca
     8101 atatctcctg caaggatttt aagaaaagtt gattttccgg caccattcgc accgattaag
     8161 ccgtaagtat tgccggctgt gaatttgata ttaacatcat caaatagttt tcgatcacta
     8221 aagcgtagtg atacatcaga aactgtaagc aatttgtcac ctcatcttat ttatctaagc
     8281 ttcattgtac ctaaaatagt cccctttttc aatcagaaaa gggctaatca ctacataggc
     8341 aataaaacgt ctttgtcttc acgtttgtat tgtttagtca aactaaatcc tcttcccata
     8401 acttgagctg ctggcatgac aacaataaag gctgtgtcgt caatttcgag gattttttct
     8461 tggagagtgg gtaattcgtg acttgataca atagccatta acataatttt atcagaagta
     8521 gtataaccac cgcgaatagg aagtttagtc actccacgat ccataacagt tgtgatatat
     8581 tctcgaatag cttgataatc tttggaaata atcataacat ttttggatga gtcaaagcca
     8641 ttttccataa cgctaatcac ataaccaatt acgaaaagtc caatcgtaga atacatcacg
     8701 tcatctgcag aaagtgcaat aaatcccata aggacactaa taccatctac aattgtcatt
     8761 gcaactccaa gagataaagg agagtattta tgaagtattt gtgttagaat tccagttcct
     8821 cctgtcgaag agtttcccca aaaaaccatt cctaaaccaa tgccacagat aataccacca
     8881 aaaatagctg ctaataactg attgtgtgtc agagtaggta atgaattggt tgaacggatg
     8941 gcaataggat atatccaaga accataaagt gttttaataa aattttgttt tccaagaaag
     9001 aagtaacaca ttaataataa gggaatatta ctagccatta aaaaaagcga cggactaatg
     9061 ccaaatagag cttttataac aactgcaata ccaaccatac cccctgatgc aatatgattg
     9121 tcgacaaaca ttgtattgaa accaatagct gttatgaatg agccaattgt gacaagtagt
     9181 aaatcaatcc ctcgtttttt catgctttta atctccttta taactggtta aaaatagtag
     9241 actcattatc tcttaaatgt actgagaccg tcaagtcata ttttcaaaaa atctggtgaa
     9301 cttgacaaga agtttaaaat ttcatagaat aaatctaaat tagaagagta ttcttttcat
     9361 gtttttagag agttagtggt tggtgcaagc taacaacaga aaaggtgaaa tggactaatg
     9421 attatttgaa aggaaaccat aactttcagg ttggcacccc ttaccgtgca gcttctttca
     9481 ttgagaagat tgagatagta tctcgttttg ataaagcaga tgctaattga ggtggtaccg
     9541 cgtattactt gtaataacgc cctcacgttt taatagcgtg gggacttttt gctatatcaa
     9601 gagatagtta gggagaaaat gatgacaaaa cctattattt taactggaga tagaccaact
     9661 ggaaaattac atttaggtca ttatgtcgga agtcttaaaa atcgtgtctt tttacaaaat
     9721 gaaaacaagt ataagatgtt tgttttcttg gccgatcaac aggcactgac ggatcatgct
     9781 aaagaatccg aattaattca agaatctatt ggaaatgttg ccttggatta cctctctgtc
     9841 ggtttggatc cgaagcaatc aacgattttt attcaaagtc agattccaga gctagctgaa
     9901 ttgagcatgt attatatgaa tctggtatca ttagcacgtt tggaaagaaa tcccactgtt
     9961 aaaaccgaaa ttgctcagaa aggttttggc gaaagtattc catctggttt tttggtttat
    10021 ccagtatcac aggccgctga tattacagca tttaaagcga atttagtacc tgtaggtaac
    10081 gaccagaaac cgatgattga acaaacacgt gaaattgtga gaagttttaa tcatacttac
    10141 catacagact gtttagtaga acctgaaggt atttatccag aaaatgaaaa agctggacgc
    10201 ttacctggtc ttgatggcaa tgccaaaatg tctaaatcat tgggaaatgg aatctatctc
    10261 tcagatgatg cagataccgt tcgcaaaaaa gtgatgagca tgtatactga tccaaatcat
    10321 attaaaatag aagatcctgg tcaaattgaa gggaatatgg tctttcatta tttggatatt
    10381 tttgctagaa aagaagatca agctgatatc gaagcaatga aagagcatta tcaaagaggt
    10441 ggtttaggag atgtgaaaac gaaacgctac cttctagata ttttagaacg tgaattagca
    10501 cctattcgtg aaagacgttt ggagtacgct aaagatatgg gagaggtgtt ccgtatgtta
    10561 caagaaggta gtcaaaaagc aagaactgtg gcagccaaga ctttatcaga agtgaagtca
    10621 gcaatgggta ttaattattt ttaatgtttt agagaaaaag ctaagttagt aatgataaga
    10681 taattactat tatcaaagca gaacctaatt tgtcatttct ttacaggata gtagagatta
    10741 tgttttatat agtcttattt ttgattaaaa ataagaccca aatgaatttt ttgattaata
    10801 aaaaacggat aatactgata tattatgctg atagtgactt cagctgtagg aatattttat
    10861 tgacaaatga ttttagcgtg atatgatagt aacaataaaa aatagaccag ggtaatattc
    10921 cctaaaaata aaagaaaaga ggattatctg gatgtcaaat tgggacacta aatttttgaa
    10981 aaaaggctac acttttgacg atgtcttgct tattccggca gagagtcatg ttcttccaaa
    11041 tgaagttgat ttaaagacaa agctcgcaga caatttgaca ttaaatattc ctattattac
    11101 agcagctatg gatacggtta ctggtagtaa aatggctatt gcaattgcgc gtgcgggtgg
    11161 tttaggtgtt attcataaaa acatgtctat tactgagcaa gcagaagaag ttcgcaaggt
    11221 aaaacgttct gaaaatggtg tcatcattga tccattcttc ttaacacctg aacacaaggt
    11281 ttcagaagct gaagaattaa tgcagcgcta ccgtatcagt ggtgtgccaa ttgttgaaac
    11341 tttagcaaac cgtaagttgg tcggtatcat tactaatcgt gatatgcgtt ttatttctga
    11401 ttacaatgca ccaatctctg aacatatgac tagtgagcac ctcgttacgg ctgctgttgg
    11461 tacagatctt gaaactgcag aacgtattct tcatgaacac cgtattgaaa aacttccttt
    11521 ggttgataat agcggtcgtc tgtctggttt aatcactatc aaagatattg aaaaagtaat
    11581 cgaattccca catgctgcta aagatgaatt tggtcgtctt ctggtcgctg ctgcggtagg
    11641 tgttacctca gatacttttg agcgtgccga ggccttgttt gaagctggtg cagatgcgat
    11701 tgttattgac acagctcatg gtcattcggc tggtgttctt agaaaaattg ctgaaattcg
    11761 tgctcatttt ccaaatcgta ctttgattgc tggaaatatt gccactgctg aaggtgcgcg
    11821 tgctctttat gatgcaggtg ttgatgttgt taaagtgggt attggtcccg gatctatctg
    11881 taccactcgt gtggttgcag gtgtcggtgt tcctcaagtg actgctattt acgatgctgc
    11941 tgctgttgct cgtgaatatg gcaaaacgat tattgctgat ggtggtatca agtattctgg
    12001 cgatattgtt aaggctcttg cagccggtgg taatgctgtt atgcttggat caatgtttgc
    12061 aggtactgat gaagctccag gtgaaactga aatctaccaa ggccgtaagt tcaaaactta
    12121 tcgtggaatg ggttccattg cagctatgaa gaaaggatca agcgatcgtt acttccaagg
    12181 ttccgtcaat gaagctaata agttagttcc agaaggtatt gaaggccgtg ttgcttataa
    12241 aggagctgct tcagatattg tcttccaaat gttaggtggt atccgctcag gtatgggcta
    12301 tgttggcgca ggtgacattc aagaattaca tgaaaatgct caatttgttg aaatgtcagg
    12361 tgcaggcttg attgaaagtc atccacatga tgtccaaatc acaaatgaag caccaaacta
    12421 ttctgtgcac tgataattta atttagtaac tttaagggct gacatattgt gccagctctt
    12481 tttttatatt aaaaaatgat aaaa
//
LOCUS       DAUCXI010000044        11929 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.044, whole genome shotgun sequence.
ACCESSION   DAUCXI010000044 DAUCXI010000000
VERSION     DAUCXI010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11929
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.044"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            306..1907
                     /locus_tag="VGY43_001459"
     CDS             306..1907
                     /locus_tag="VGY43_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ4302630.1"
                     /translation="MHVSKLFTSQQWRELKLISYLTENSNAIGVKDKELSKALNISML
                     TLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFR
                     DFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLK
                     YFSEAYKISEWPFGDILNLKNCERLLSLLIKEVDVKVRFTLFQHLKILSGVNLIRYYK
                     GYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLE
                     IGCAFEIINQDPTSGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDI
                     TANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVSKELINQLTYCFFIT
                     WENSFLKVNQKDEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIE
                     KQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKNLEAPSP
                     SKSHSDKEVQKPEKPDNSVNQATSS"
     gene            2095..3354
                     /locus_tag="VGY43_001460"
     CDS             2095..3354
                     /locus_tag="VGY43_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEQ4302631.1"
                     /translation="MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLATGQTIKADTS
                     EQEHPNITKIKEQLLRNKLVPATQWYQAYTKSEELSRQVEKLQTLVQSKTSNYEKIKS
                     QLQELEQSKKALEDTFYSTLRDHSSLFKEQDKEIKNMRAQLEFKNKQISDLTNENAQL
                     KEAIEGYVQTIQNASREIAAKQQELAAAKSQLEAKNAEIEALKQQDASKTEEIAKLQS
                     EAATLENLLGSAKRELTDLQAKLDTATAEKAKLESQVTTLENLLGSAKRELTDLQAKL
                     DAANAEKEKLQSQAAALEKQLEATKKELADLQAKLAATNQEKEKLEAEAKALKEQLAK
                     QAEELAKLKADKASGAQKPDTKPGNKEVPTRPSQTRTNTNKAPMAQTKRQLPSTGEET
                     TNPFFTAAALTVIASAGILALKRKEES"
     gene            3579..4676
                     /locus_tag="VGY43_001461"
     CDS             3579..4676
                     /locus_tag="VGY43_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561044.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEQ4302632.1"
                     /translation="MARKDTNKQYSLRKLKTGTASVAVAVAVLGAGFTNQTTVKADSS
                     SRDITEAGVSKFWKSKFDAEQNRANELEKKLSGYEKDYKTLEQEYENLEETLQKFGND
                     YERLENKNNEYANQLGKNQEEREKLELEYLRKSDKEYKEHQQYRQEQEERQKNLEELE
                     RQNKREIDKRYQEQLQKQQQLETEKQISEASRKSLSRDLEASRAAKKGLEAEHQKLKE
                     EKQISDASRKSLSRDLEASREAKKKVEADLAEANSKLQALEKLNKELEEGKKLSEKEK
                     AELQARLEAEAKALKEQLAKQAEELAKLKGNQTPNAKVAPQANRSRSAMTQQKRTLPS
                     TGEAANPFFTAAAATVMVSAGMLALKRKEEN"
     gene            4696..5160
                     /locus_tag="VGY43_001462"
     CDS             4696..5160
                     /locus_tag="VGY43_001462"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302633.1"
                     /translation="MINKFQRPSKKYYFLIALASLVLLGTSKTVFGESMTLYTGDYWY
                     EEDGGMLNGNHWGMENWWEPSSLWAPYPNPHYSENDPHQPPYGGSLLGLSSDNERERG
                     PRPTPSPQSPLTPESNPNNSRNQGPVNSPWPQGPLFGGLTSGTTSSWGSVIK"
     gene            5465..6589
                     /gene="enn"
                     /locus_tag="VGY43_001463"
     CDS             5465..6589
                     /gene="enn"
                     /locus_tag="VGY43_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M-related protein Enn"
                     /protein_id="HEQ4302634.1"
                     /translation="MTRQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVRADQA
                     ASEKVEVKESEKETKYKTLALRGENADLRNVNAKYLEKINAEEEKNKKLEATNKELNE
                     NYYKLQDGIDALEKEKEDLKTTLAKTTKENEISEASRKGLSRDLEASRAAKKELEAKH
                     QKLEAENKKLTEANQISEASRKGLSNDLEASRAAKKELEAKHQKLEADHQALEAKHQK
                     LAEEHQVSETSRKGLSRDLEASREANKKVTSELTQAKAQLLALEESKKLSEKEKAELQ
                     AKLDAQGKALKEQLAKQTEELAKLRAEKAAGSKTPATKPANKERSGRAAQTATRPSQN
                     KGMRSQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN"
     gene            6924..10472
                     /gene="scpA/B"
                     /locus_tag="VGY43_001464"
     CDS             6924..10472
                     /gene="scpA/B"
                     /locus_tag="VGY43_001464"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HEQ4302635.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VETPQPTAVSEEAPSSSKETNPPQIPDDAEETVADKANDPAPQAPAKTADTPATSKAT
                     IRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKA
                     KKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEG
                     AMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDET
                     KKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSP
                     DKQLTETATVKTDDHQAKEMPVLSTNRFEPNKAYDYAYANRGTKEDDFKDVKGKIALI
                     ERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDN
                     PQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAK
                     LSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYF
                     SPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELY
                     YQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMK
                     NGYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSD
                     AKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGT
                     FAKQNDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGN
                     VVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPIS
                     SGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDE
                     DLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLE
                     GHSNKPEQDGSDQAPDKKPETKPEQDGSDQAPDKKPETKPEQDGSGQAPDKKPEAKPE
                     QDGSGQTPDKEPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASTRDQLP
                     TTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED"
     gene            10569..11837
                     /gene="fbpA"
                     /locus_tag="VGY43_001465"
     CDS             10569..11837
                     /gene="fbpA"
                     /locus_tag="VGY43_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibronectin-binding protein FbpA"
                     /protein_id="HEQ4302636.1"
                     /translation="MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDSMQQN
                     SSTQRNTANTSKKWYHIDDRGFIPVDISLETAKEDFKKEVKESRLSEEQQKTYNQKIE
                     AAKNKDDLLLTYHREYSEDIKKHPASTEPTTQPVEAPVQETQAPASDSMVTGDSTSVT
                     ADSPKETPSSESPVAPAPSIPEVPEAPASSPESEKSSVAASSEETSSPETPAAPEAPA
                     LSEAPAQPAESEKPSVAAPSEETPSPETPVAPETPEEPAAPAPSPESEEPSVAAPSEE
                     TPSPAAPALSEAPAQPAESEKPSVAASSEETPSPSTPAESETQTPPAVTKDSDKPSSA
                     AEKPAASSLVSEQTVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVRAHESGKYLPSTGE
                     KAQPLFIATMTLMSLFGSLLVTKRQKETKK"
BASE COUNT         4421 a         2377 c         2314 g         2817 t
ORIGIN      
        1 agaaatgaag ttcaaaaaat ataaataaaa taaaacacca gaactgctaa aagcagtgaa
       61 tgacataaat gtcgctaaaa aaatagatag aagagtctaa aatttcagtt ttaggtcacg
      121 ttttatggat agaaatcagg atgatgacct taagttgtga tttgcgcatc attgaccgct
      181 ttactcgttt taatgaaaga atttgaaaga tattttatgg tatacttttc attaatatgg
      241 ttcatacgga cttgataaat ctatttacaa aaataataaa aaattaagat aaggacatga
      301 agttaatgca tgtaagtaaa ttgtttacta gccaacaatg gagagaattg aaactgatct
      361 catatttaac agaaaactcc aatgctatcg gagttaaaga taaggagctt agcaaggctc
      421 tcaatatttc catgttaaca ttacagtcat gcctcactaa tatgcagttt atgaaagaag
      481 taggtggaat tacctacaaa gacggctata ttaacatttg gtatcaccag tgttgtgggc
      541 tacaagaggt ctatcaaaaa gctcttcgag aatcgccttc tttgaaatta ctggagcttt
      601 tgtttttcag agactttagt tccttagaag agttagctga agagctgttt gtcagtttat
      661 ctaccctcaa acgcctcatc aaaaaaacca acacttactt gtctcatacc tttgctatta
      721 gtatcgtgac aagtccagtg caggtatcag gagatgagag gcaaatccgc ctgttttacc
      781 tcaagtattt ttcagaagcc tataaaatct cagaatggcc atttggggac attttaaacc
      841 tgaaaaactg tgaacgccta ttgagcttat tgatcaaaga agtagatgtc aaagttcgtt
      901 ttacactatt tcagcactta aaaatcttaa gtggtgtcaa cttgatccgt tactacaagg
      961 ggtattcttg cagttataac aataaaaaaa ccagtcaccg tttttctcaa cttatccaac
     1021 attcctcaga aatccaggat ctttctcgct tgttctacct caaatttggg ttacatctcg
     1081 acgagtatac catagctgaa atgttttcta accatcttaa cgacaagcta gaaattggct
     1141 gtgcttttga gattatcaat caagacccaa catcaggagg cagacaagta accaactgga
     1201 tccatctatt agatgagatg gaaatcaagc tcaatctcag catcaccaat aaatacgaag
     1261 ttgctgtaac cctccataac gcttcggtgt taaacgaaga agacattaca gccaattatt
     1321 tgctgtttga ttataaaaag agttacctga acttttacca aaaagaacac cctcgtatct
     1381 atgaggcctt tgtgacaagt gtcgagaagc tgatgcaggc agataatgct caagttagca
     1441 aagaattgat caatcagctc acttattgtt tctttattac ctgggaaaat agtttcttaa
     1501 aagtaaatca aaaagatgaa aaagtacgac ttctagtgat agagagaagt tacaatagtg
     1561 tcggtaattt tttgaaaaag tacatcggtg agtttttcag cattactaat tttgatgagt
     1621 tagattgttt gacaattgat ctagtagaga ttgaaaaaca gtacgatgtt atcgtgacag
     1681 atgttatggt gggtaaaagc gaagagttag agattttctt tttctacaag atgatcccag
     1741 aagctattat tgatagatta aacgaatttt tgaacgttag tttcacagat aacaacgtta
     1801 tggtcaaaaa cctcgaagcc ccttcccctt caaaatctca tagtgacaaa gaggtacaaa
     1861 agccagaaaa gccagacaat tcagttaatc aagcaacatc atcataggat ttcagacgtc
     1921 atggtaagaa aaaaaagaat catttacagc ccatagaggt aaggtcaaaa gctgaaagca
     1981 gctcaaaaaa actgaccttt accttttggc tttttttatt tagaataatt ttattggaga
     2041 gatgcttaat aatttaagca caattcttag aaattgagaa ataaggagta aacaatgtct
     2101 aaaagaaatc caaacaaaca ctactcactg agaaagttaa aaacaggtac tgcatcagta
     2161 gcagtagctt tgacagtttt ggggactggg ttagcaactg gacaaacaat aaaagctgat
     2221 accagtgaac aagaacaccc gaacattaca aagatcaaag aacagctttt acgcaataag
     2281 ttggtccctg ctacacaatg gtaccaagcc tatactaaaa gcgaggaact tagtcgtcag
     2341 gtcgaaaaac ttcagacctt ggtccaatca aagacctcaa attatgaaaa gataaagtca
     2401 cagttacaag agttggagca atctaaaaag gctttggagg acacttttta cagtacactt
     2461 agagatcact caagtctttt caaagaacaa gataaagaaa tcaaaaatat gagggcccag
     2521 cttgagttta aaaacaagca aatctcagat ttaaccaacg aaaacgcaca gttaaaagaa
     2581 gccattgaag gttatgtgca aactatccaa aacgctagtc gtgaaatcgc agcaaaacaa
     2641 caagaacttg cagctgcaaa aagccagtta gaggcaaaaa atgctgagat tgaggcattg
     2701 aaacaacaag atgcctctaa gactgaagaa attgctaaat tgcaatcaga agcagcaact
     2761 ttagaaaacc ttctaggttc agccaagcgt gagttgactg acttgcaagc taagctagat
     2821 acagcaactg ctgaaaaagc aaaactagaa tcacaagtaa caaccttaga aaaccttcta
     2881 ggttcagcta agcgtgaatt gactgatctg caagctaagc tagatgcagc taacgctgaa
     2941 aaagaaaagc tccaatcaca agcagcagcc ctagaaaaac aactagaagc aactaaaaaa
     3001 gagttagctg atttacaggc taaattagca gcaaccaacc aagaaaaaga aaagttagaa
     3061 gctgaagcaa aagctcttaa agagcaatta gcaaaacaag ctgaagagct tgctaagcta
     3121 aaagcagata aagcttcagg ggctcaaaaa ccagatacta aacctggcaa taaagaggtt
     3181 ccaacaagac catcacaaac aagaacaaac actaataaag ctcctatggc gcaaacaaag
     3241 agacaattac cgtcaacagg cgaagaaaca accaacccat tcttcactgc agcagcattg
     3301 acagtgatcg catctgcagg catacttgcc ctaaaacgca aagaagaaag ctaagcccaa
     3361 ctcacaatat cttttctagc ccaagaaaaa aacaaaaaaa gaggaagacc attcctcttt
     3421 ttttgaacgg ttgaaaagca aaaaggtcaa aaaggcacta aagtctcaaa aacctggtct
     3481 ttacctttta ccgcttattc tttagaatag aattattaga gagaagtctt agaaaaatga
     3541 ggctaattcc ctaaagatga aaaaataagg agcaaataat ggctagaaaa gatacgaata
     3601 aacagtattc gcttagaaaa ttaaaaacag gtacagcatc agtagcggtc gctgtggctg
     3661 ttttaggagc aggctttaca aaccaaacaa cagttaaggc ggactcttct agtagagata
     3721 tcactgaggc aggtgtatct aagttttgga agagtaagtt tgatgcagag cagaatagag
     3781 caaacgagct tgaaaaaaaa cttagtggat acgaaaaaga ttataaaaca ttagaacaag
     3841 agtatgaaaa tctagaagaa actttacaaa aattcggaaa tgattatgaa agattagaaa
     3901 acaaaaataa tgagtacgca aatcaacttg gtaaaaatca agaagaacgc gaaaaattag
     3961 agcttgaata cctcagaaaa tcagataaag agtataaaga gcatcaacaa tatcgacaag
     4021 aacaagaaga acgtcaaaaa aatctagagg aacttgaacg tcaaaataaa cgagaaatag
     4081 acaaacgcta tcaagaacaa ctccaaaaac aacaacaatt agaaacagaa aagcaaatct
     4141 cagaagctag tcgtaagagc ctaagccgtg acctcgaagc ttctcgtgca gctaaaaaag
     4201 gccttgaagc tgagcaccaa aaactcaaag aggaaaaaca aatctcagac gcaagccgta
     4261 agagcctaag ccgtgacctt gaagcgtctc gcgaagctaa gaaaaaagta gaagcagact
     4321 tagccgaagc aaatagcaaa cttcaagccc ttgaaaaact aaacaaagag cttgaagaag
     4381 gtaagaaatt atcagaaaaa gaaaaagctg agttacaagc aagactagaa gcagaagcaa
     4441 aagctcttaa agagcaattg gctaaacaag ctgaagaact tgccaaacta aaaggcaacc
     4501 aaacaccaaa cgctaaagta gccccacaag ctaaccgttc aagatcagca atgacgcaac
     4561 aaaagagaac gttaccgtca acaggcgaag cagctaaccc attctttaca gcagcagctg
     4621 caacagtgat ggtatctgca ggtatgcttg ccctaaaacg caaagaagaa aactaaaata
     4681 taaaagggat caatgatgat taacaaattt caacgtccgt ctaaaaaata ttattttctt
     4741 atcgctttgg caagtttagt gctgttggga acttctaaga ccgtctttgg agaatcaatg
     4801 acactgtata caggagatta ttggtacgag gaagatggtg gtatgttaaa cggaaaccac
     4861 tggggaatgg aaaattggtg ggagccatca agtttgtggg ctccttatcc aaatcctcac
     4921 tatagtgaaa acgatccaca ccagccacct tatggcggat ccttattggg attatcctca
     4981 gataatgaga gagaacgtgg gcctagacct actccatcgc cacagtctcc tttaactccg
     5041 gagtcaaatc ctaacaactc tagaaatcag ggtcctgtta atagcccatg gcctcaaggt
     5101 ccgctttttg gaggattaac aagtggaact acctccagtt ggggaagtgt tattaaatag
     5161 tttgttataa gttatccata atttctaaat caaacaaccg ccccattctt tacagtagca
     5221 ggtatgcttg ctctaaaacg taaagaagaa aactaagcta ttagactgat gctaaagcta
     5281 agagagaatc aaatgattct ctctttttga gtagctaagt aactaacaat ctcagttaga
     5341 ccaaaaaatg agaatggctc aaaaagctgg cctttactcc ttttgattaa ccatatataa
     5401 taaaaacgtt aggaaaataa tagcactatt aagttgcttt ttcaataaaa tcaaggagta
     5461 gataatgact agacaacaaa ccaagaaaaa ttattcacta cggaaactaa aaaccggtac
     5521 ggcttcagta gccgttgctt tgaccgtttt gggcgcaggt tttgcaaacc aaacggaagt
     5581 aagagctgat caagcagctt ctgaaaaagt ggaagtaaaa gaaagtgaaa aagagaccaa
     5641 gtataagacg ttggccttaa gaggtgaaaa tgctgacctt agaaatgtaa atgcaaaata
     5701 tttagagaaa attaacgcag aagaagaaaa aaataaaaag cttgaagcaa ctaataaaga
     5761 gctaaatgag aattattaca aattacaaga tggcattgat gctttagaaa aagaaaaaga
     5821 agatctcaaa acaactttag ctaagactac taaagaaaat gagatttcag aagctagccg
     5881 taaagggtta agccgagact tagaagcttc tcgtgcagct aaaaaagagc tagaagctaa
     5941 gcatcaaaaa ttagaagcag aaaacaaaaa actaacagaa gccaatcaga tttcagaagc
     6001 tagtcgtaaa ggtctaagta acgacttaga agcttctcgt gcagctaaaa aagaactaga
     6061 agctaagcac caaaaattag aggctgatca ccaagcccta gaagctaagc accaaaaatt
     6121 agcagaagaa catcaagttt cagagactag ccgcaagggt ctaagccgtg accttgaagc
     6181 atcacgtgaa gctaataaga aggttacatc tgagttaaca caagcaaaag ctcaactctt
     6241 agcgcttgaa gaaagtaaga aattatcaga aaaagaaaaa gctgagttac aagcaaaact
     6301 agatgcacaa ggaaaagccc tcaaagaaca attagcaaaa caaactgaag agcttgcaaa
     6361 actaagagct gaaaaagcag caggttcaaa aacacctgct accaaaccag ctaataaaga
     6421 aagatcaggt agagctgctc aaacagctac aagacctagc caaaataaag gaatgagatc
     6481 acaattaccg tcaacaggcg aagcagctaa cccattcttt acagcagcag ctgcaacagt
     6541 gatggtatct gcaggtatgc ttgctctaaa acgcaaagaa gaaaactaag cctttaaaac
     6601 ttggtttttg taacgatgca atagacaaaa gcaagcaagg ccaaaaactg agaaagtcct
     6661 aaaaagctgg cctttacccc tcaaaattaa tgttttataa taaagatgtt agtaatataa
     6721 ttgataaatg agatacattt aatcattatg gcaaaagcaa gaaaaatagc tgtatcatat
     6781 gcaaataacc cctgtttgct ctttaaaaaa gacgttatcc ttatttctcc acgcacagat
     6841 ggacagctag gagagaatcg tttgattctc tcttttctta atggtcataa agacaaagtc
     6901 tctcatcatg aaaggacgac acattgcgta aaaaacaaaa attaccattt gataaacttg
     6961 ccattgcgct catgtctacg agcatcttgc tcaatgcaca atcagacatt aaagcaaata
     7021 ctgtgacaga agacactcct gctaccgaac aagccgtaga aactccacaa ccaacagcgg
     7081 tttctgagga agcaccatca tcatcaaagg aaactaaccc tccacaaatt cctgatgacg
     7141 cagaagaaac agtagcagat aaggctaatg atccagcccc tcaagctcct gctaaaactg
     7201 ctgatacacc agcaacctca aaagcgacta ttagggattt gaacgaccct tctcaggtca
     7261 aaaccctgca ggaaaaagca ggcaagggag ctgggactgt tgttgcagtg attgatgctg
     7321 gttttgataa aaatcatgaa gcgtggcgtt taacagacaa aaccaaagca cgttaccaat
     7381 caaaagaaga tcttgaaaaa gctaaaaaag agcacggtat tacctacggc gagtgggtca
     7441 atgataaggt tgcttattac cacgactata gcaaagatgg taaaaccgct gtcgatcaag
     7501 agcacggcac acacgtgtca gggatcttgt cagggaatgc tccatctgaa acgaaagaac
     7561 cttaccgcct agaaggtgcg atgcctgagg ctcaattgct tttgatgcgt gtcgaaattg
     7621 taaatggact agcagactat gctcgtaact acgctcaagc tatcagagat gctgtcaact
     7681 tgggagctaa ggtgattaat atgagctttg gtaatgctgc actagcttac gccaaccttc
     7741 cagacgaaac caaaaaagcc tttgactatg ccaaatcaaa aggtgttagc attgtgacct
     7801 cagctggtaa tgatagtagc tttgggggca agacccgtct acctctagca gatcatcctg
     7861 attatggggt ggttgggaca cctgcagcgg cagactcaac attgacagtt gcttcttaca
     7921 gcccagataa acagctcact gaaactgcta cggtcaaaac agacgatcat caagctaaag
     7981 aaatgcctgt tctttcaaca aaccgttttg agccaaacaa ggcttacgac tatgcttatg
     8041 ctaatcgtgg gacgaaagag gatgatttta aggatgtcaa aggcaaaatt gcccttattg
     8101 aacgtggcga tattgatttc aaagataaga ttgcaaacgc taaaaaagct ggtgctgtag
     8161 gggtcttgat ctatgacaat caagacaagg gcttcccgat tgaattgcca aatgttgacc
     8221 agatgcctgc ggcctttatc agtcgaaaag atggtctctt attaaaagac aatccccaaa
     8281 aaaccatcac cttcaatgcg acacctaagg tattgccaac agcaagtggc accaaactaa
     8341 gccgcttctc gagctggggt ctgacagctg acggcaatat taagccagat attgcagcac
     8401 ccggccaaga tattttgtca tcagtggcta acaacaagta tgccaaactt tctggaacta
     8461 gtatgtctgc gccattagta gcgggtatca tgggactgtt gcaaaagcaa tatgagacac
     8521 agtatcctga tatgacacca tcagagcgtc ttgatttagc taaaaaagta ttgatgagct
     8581 cagcaactgc cttatatgat gaagatgaaa aagcttattt ttctcctcgc caacaaggag
     8641 caggagcagt cgatgctaaa aaagcttcag cagcaacgat gtatgtgaca gataaggaca
     8701 atacctcaag caaggttcac ctgaacaatg tttctgataa atttgaagta acagtaacag
     8761 ttcacaacaa atctgataaa cctcaagagt tgtattacca agcaactgtt caaacagata
     8821 aagtagatgg aaaacacttt gccttggctc ctaaagcatt gtatgagaca tcatggcaaa
     8881 aaatcacaat tccagccaat agcagcaaac aagtcaccgt tccaatcgat gctagtcgat
     8941 ttagcaagga cttgcttgcc caaatgaaaa atggctattt cttagaaggt tttgttcgtt
     9001 tcaaacaaga tcctaaaaaa gaagagctta tgagcattcc atatattggt ttccgaggtg
     9061 attttggcaa tctgtcagcc ttagaaaaac caatctatga tagcaaagac ggtagcagct
     9121 actatcatga agcaaatagt gatgccaaag accaattaga tggtgatgga ttacagtttt
     9181 acgctctgaa aaacaacttt acagcactta ctacagagtc taacccatgg acgattatta
     9241 aagctgtcaa agaaggagtt gaaaacatag aggatatcga atcttcagag atcacagaaa
     9301 ccatttttgc aggtactttt gcaaaacaaa acgatgatag ccactactat atccaccgtc
     9361 acgctaatgg caaaccatat gctgcgatct ctccaaatgg ggacggtaac agagattatg
     9421 tccaattcca aggtactttc ttgcgtaatg ctaaaaacct tgtggctgaa gtcttggaca
     9481 aagaaggaaa tgttgtttgg acaagtgagg taaccgagca agttgttaaa aactacaaca
     9541 atgacttggc aagcacactt ggttcaaccc gttttgaaaa aacgcgttgg gacggtaaag
     9601 ataaagacgg caaagttgtt gctaacggaa cctacaccta tcgtgttcgc tacactccga
     9661 ttagctcagg tgcaaaagaa caacatactg attttgatgt gattgtagac aatacgacac
     9721 ctgaagtcgc aacatcggca acattctcaa cagaagatcg tcgtttgaca cttgcatcta
     9781 aaccaaaaac cagccaaccg gtttaccgtg agcgtattgc ttacacttat atggatgagg
     9841 atctgccaac aacagagtat atttctccaa atgaagatgg tacctttact cttcctgaag
     9901 aggctgaaac aatggaaggc gctactgttc cattgaaaat gtcagacttt acttatgttg
     9961 ttgaagatat ggctggtaac atcacttata caccagtgac taagctattg gagggccact
    10021 ctaataagcc agaacaagac ggttcagatc aagcaccaga caaaaaacca gaaactaaac
    10081 cagaacaaga cggttcagat caagcaccag acaaaaaacc agaaactaaa ccagaacaag
    10141 acggttcagg tcaagcacca gacaaaaaac cagaagctaa accagaacaa gacggttcag
    10201 gtcaaacacc agataaagaa ccagaaacta aaccagaaaa agatagttca ggtcaaacac
    10261 caggtaaaac tcctcaaaaa ggtcaacctt ctcgtactct agagaaacga tcttctaagc
    10321 gtgctttagc tacaaaagca tcaacaagag atcagttacc aacgactaat gacaaggata
    10381 caaatcgttt acatctcctt aagttagtta tgaccacttt cttcttggga ttagtagctc
    10441 atatctttaa aacaaaacgc actgaagatt agtacaactg atcagatggc tactattgat
    10501 gatgagttag atcagtcttc ttttcaaaag aaggcatagc agtataaaaa tagatatgtg
    10561 aggacaatat gcgtagagca gaaaataaca aacacagccg ctattccatt cgcaaactga
    10621 gcgttggggt aacgagtata gcaattgcga gtctcttttt aggaaaggtt gcctatgccg
    10681 tagatagcat gcagcaaaac tcttcgactc aaagaaacac agccaataca tccaaaaaat
    10741 ggtatcatat tgatgatagg ggctttattc ctgtagatat aagcttagaa actgccaaag
    10801 aggattttaa aaaagaagta aaagaatcac gtttgtctga agaacaacag aaaacgtata
    10861 atcaaaaaat tgaagctgca aaaaacaaag acgacctatt gttaacatat catagagagt
    10921 actctgaaga tattaagaaa cacccagcgt ctactgagcc tactactcag ccagttgagg
    10981 cacccgtgca ggagacacag gccccagctt cagattcgat ggtgacaggt gattcaacat
    11041 cagttacggc tgattctcct aaggaaaccc catcttcgga aagtccagta gccccagctc
    11101 catcaattcc agaggtccca gaagccccag cttcatcacc tgagagtgag aaatcttcag
    11161 tagcagcttc ttctgaggaa acctcatctc cagaaactcc agcggcccca gaagccccag
    11221 ctttatctga ggctccagct caaccagctg agagtgagaa accttcagta gcagctcctt
    11281 ctgaggaaac cccatctcca gaaactccag tggccccaga aactcctgaa gagccagcag
    11341 ctccagctcc atcacctgag agtgaggaac cttcagtagc agctccttct gaggaaaccc
    11401 catctccagc ggccccagct ttatctgagg ctccagctca accagctgag agtgagaaac
    11461 cttcagtagc agcttcttct gaggaaaccc catctccatc aactccagct gaatcagaga
    11521 ctcagacgcc accagctgtt actaaagact ctgataagcc atcttcagca gctgaaaaac
    11581 cagcagcctc ttcacttgtt tcagaacaaa ccgttcaaca accaacttca aagagatctt
    11641 ctgataaaaa agaagagcaa gaacagtctt actctccaaa tcgctcattg tcaagacagg
    11701 ttagggccca tgagtcaggt aagtacttgc cttcaacagg tgaaaaagcg cagccactct
    11761 ttatagctac tatgactttg atgtctctat ttggaagtct tttagtcaca aaacgccaaa
    11821 aagaaactaa aaaatagtat tacttaaact gataagagct tatttaatag agagaaccaa
    11881 tttggttctc tctatttttt tagatgtgct gcctcatcaa aaagaagtt
//
LOCUS       DAUCXI010000045        11883 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.045, whole genome shotgun sequence.
ACCESSION   DAUCXI010000045 DAUCXI010000000
VERSION     DAUCXI010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11883
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.045"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(28..765)
                     /locus_tag="VGY43_001466"
     CDS             complement(28..765)
                     /locus_tag="VGY43_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302637.1"
                     /translation="MNQLLLKNVCKRYPNQPNYALDHINLTVRKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGSIYCADKEISVFSDNEATSFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNIDSSKIDDLINSYAKRFNLYEQLKKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEETMMILSEINKTEKVTILMVTHDVLSASYADRVVLLKDGK
                     LHMEIDKKDCGESFYDVISQALSDRGE"
     gene            complement(762..1295)
                     /locus_tag="VGY43_001467"
     CDS             complement(762..1295)
                     /locus_tag="VGY43_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302638.1"
                     /translation="MDKKDFRDISAFVSQDSPIFDGDVMYNISLGRESVSGEQVIETC
                     KRVSIYDDIISMPMKFHTPLFRDNPSLSGGQKQRISLARELVTTPRILVLDEPTSALD
                     VKTERIIQKNVEALHCTRVLVTHRLNTVEKADKILIMDNGKIIDYGSHHCLYKNNEYY
                     RDLYDSYMNNYQEEGIK"
     gene            complement(1297..2922)
                     /locus_tag="VGY43_001468"
     CDS             complement(1297..2922)
                     /locus_tag="VGY43_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HEQ4302639.1"
                     /translation="MIKRDELKLEYQNHQFYEYVNSIFDYDILDTSIRETSEVLRKKT
                     HKLFYSEFENQLFETIMFLSMKTLVLDINHFSKEIENKSEAYEQYIQQIREENGINHF
                     FDRYPYLLKQINKEVGLIEESYSLLFDRFLEDLSEIRSCFNISEPLSNVAFSLGDSHS
                     KKQTVVKIAFKEKSVYYKPKSYHSHSILLELTSLLKSSNIPSFSLPKSLVKADYCWQL
                     GVAYTSSNKDEVAKIYFKYGVLAAFSEIFSITDLHMENVIVSGGDLYLIDVETFFQRK
                     LNVQNQNFEGITVDTYQRIYETSLSNGLFPVQFEKNSAPNVSGISGKGGKRKKGKYEL
                     INKNRGDMKLVKTDYFQEDGYNIPTLNGKVVEPLDYANEVIADFRECYTFLMSQRAKV
                     KKILEDFPKLKTRAIFRNTSDYGKFLQASTNPKYLFSEKKRENLFSILHESKHIEQFI
                     VVSEIKDLMNGDIPYFSMDTSGNVYNSLGTVIGNLGETTSLFDNIATLNDERMKFTCE
                     LLGIVLKKPIKHWEREKGKSYQFLSISSEHYLL"
     gene            complement(3006..3161)
                     /locus_tag="VGY43_001469"
     CDS             complement(3006..3161)
                     /locus_tag="VGY43_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lantipeptide"
                     /protein_id="HEQ4302640.1"
                     /translation="MSFMENSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
     gene            complement(3666..5072)
                     /gene="lacG"
                     /locus_tag="VGY43_001470"
     CDS             complement(3666..5072)
                     /gene="lacG"
                     /locus_tag="VGY43_001470"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEQ4302641.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHAL
                     PTKYPFDANNLDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFTALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYIDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            complement(5145..6842)
                     /locus_tag="VGY43_001471"
     CDS             complement(5145..6842)
                     /locus_tag="VGY43_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ4302642.1"
                     /translation="MNGLIAQIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIENLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLSSTNQ
                     INFISTMLAAIVGFLLMAANPAKDGGFLTGFMGTKGLLTAFIAAFITVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHSTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFALFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKVYDEQILAEEAAGTNSSDVLKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKEQMEE"
     gene            complement(6842..7159)
                     /locus_tag="VGY43_001472"
     CDS             complement(6842..7159)
                     /locus_tag="VGY43_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEQ4302643.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            complement(7183..8166)
                     /gene="lacD"
                     /locus_tag="VGY43_001473"
     CDS             complement(7183..8166)
                     /gene="lacD"
                     /locus_tag="VGY43_001473"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEQ4302644.1"
                     /translation="MTITLTENKRKSMEKLSIDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEVGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDINEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKISDNASPEFAKVKAHKVNEAMKVFSEERFGVDVLKVEVPVNMKFVES
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            complement(8170..9099)
                     /locus_tag="VGY43_001474"
     CDS             complement(8170..9099)
                     /locus_tag="VGY43_001474"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEQ4302645.1"
                     /translation="MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNDFGETVKATGCVGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEIL
                     EKGPLLSVDEIDGFTHQFKYLLNDVDVVTMSGSLPAGMPDDYYQKLIKIANLNGKKTV
                     LDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFEALKEVLQDELFEGIEWI
                     IVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKA
                     NVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV"
     gene            complement(9145..9660)
                     /gene="lacB"
                     /locus_tag="VGY43_001475"
     CDS             complement(9145..9660)
                     /gene="lacB"
                     /locus_tag="VGY43_001475"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEQ4302646.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPI
                     FGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            complement(9695..10123)
                     /gene="lacA"
                     /locus_tag="VGY43_001476"
     CDS             complement(9695..10123)
                     /gene="lacA"
                     /locus_tag="VGY43_001476"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEQ4302647.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKHEVVDVSENEVRDFVDTT
                     LAVAKEVNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC"
     gene            10569..11342
                     /locus_tag="VGY43_001477"
     CDS             10569..11342
                     /locus_tag="VGY43_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEQ4302648.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLESLTFSKAFVSANAVYNNSIATYSDLEGEVQRVALNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
BASE COUNT         3741 a         2289 c         1818 g         4035 t
ORIGIN      
        1 ttagattttg taattgacca aatcatatca ctctcctcta tcggataaag cttgactaat
       61 tacatcgtaa aacgactctc cacaatcttt tttatcaatc tccatgtgaa gtttaccatc
      121 tttgagaagt acaactctat ccgcataaga agctgataaa acgtcatgag taaccattaa
      181 aatagttacc ttttctgttt tattgatttc actcaaaatc atcattgttt cctcagaaga
      241 tttcaagtca agtgctccag ttggttcgtc agcaaaaata atctctggtt ctttaatgat
      301 tgctctgata atactgaccc tctgtctttg acctccagaa agttgatacg gatatttctt
      361 caactgttca tataaattaa atctttttgc atagctattt atcaaatcat caatctttga
      421 agaatcaata ttttttagag acaaagcaac agaaatattc tccctaatgg ttagactatc
      481 taacagcata taatcttgaa aaacaaaacc aatatcattt ttcctaaaac tagttgcctc
      541 gttatcagaa aatacactaa tttctttgtc tgcacaataa atactcccac tatcaatttt
      601 atcaataatt gaagtaacat ttaaaagtgt tgtttttcca ctaccactac gtcccatgac
      661 agctacaaat tctccttttc taacagtcaa attgatatgg tctaaagcat aattcggttg
      721 gtttggatac cttttgcaaa catttttcaa tagtaattga ttcattttat cccttcctcc
      781 tgatagttgt tcatgtacga atcatataaa tcacgatagt actcattatt tttatataaa
      841 caatgatgac taccatagtc aataattttg ccattatcca ttattaaaat cttatcagct
      901 ttttcaactg tattaagtct atgggtaacc aaaaccctcg tacaatgtaa agcctcaaca
      961 tttttttgga ttattctttc agtttttaca tctaaagctg atgtcggttc gtcaagaact
     1021 aagattctag gggtagttac aagttctctt gctaaagaaa ttcgttgttt ttgcccccca
     1081 gatagtgatg gattatctcg aaaaagtgga gtatgaaact tcattggcat acttatgata
     1141 tcgtcatata ttgataccct tttacaagtt tcaataacct gttctcctga aacagattct
     1201 ctccctagcg aaatattata catcacatcc ccatcgaata tgggagaatc ttgagataca
     1261 aaagccgata tatccctaaa atctttttta tcaattttag agaaggtaat gttctgagga
     1321 gattgataaa aactgataag atttgccctt ttccctctcc caatgcttaa tcggtttttt
     1381 caagactatt ccaagcaatt cgcaagtgaa cttcattctt tcatcattca gggtagctat
     1441 attatcaaat aatgaggttg tctctcctag atttccaatt actgttccta aagaattata
     1501 tacatttcca ctggtatcca ttgaaaagta aggaatatca ccattcatca aatctttaat
     1561 ttcactaaca acaataaatt gttcaatatg ttttgactca tgtagtatcg aaaataaatt
     1621 ctccctcttt ttttctgaga aaagatactt tggattcgta gaggcttgta aaaattttcc
     1681 atagtcggaa gtatttctga atatggctct agttttcaat tttgggaaat cttctaaaat
     1741 ttttttaacc tttgcacgtt gcgacatgag aaatgtatag cattctctaa aatctgcaat
     1801 tacctcatta gcatagtcga gaggttccac cactttccca tttaatgtcg gaatattata
     1861 accatcttcc tgaaaatagt cagttttcac taacttcata tctccacgat ttttatttat
     1921 cagttcatat tttccttttt ttctttttcc accttttcca cttattccag aaacgttagg
     1981 agcgctgttt ttctcaaatt gtacaggaaa taaaccgttt gaaagtgatg tctcataaat
     2041 tctctgatag gtgtctacag taatcccttc aaaattctga ttttgtacat tcaactttct
     2101 ttgaaaaaag gtttcaacgt caattaaata taaatctccg cctgaaacaa tcacattttc
     2161 catatgtaag tccgtaatag aaaatatttc agaaaatgct gctaaaacac catacttaaa
     2221 gtaaattttc gctacttcat ctttattgga acttgtataa gctacaccaa gttgccaaca
     2281 ataatctgct ttaactaagc ttttaggaag actgaatgaa ggtatattac tagatttcaa
     2341 taaactagta agttctaaca agatactgtg tgaatgataa cttttaggct tgtagtaaac
     2401 agatttctct ttaaacgcaa ttttaacaac tgtttgcttt ttagagtgac tgtcaccaag
     2461 tgaaaaggca acattgctta ggggctcact aatgttaaag cacgacctta tctcagataa
     2521 gtcttctaaa aatctatcaa ataataaaga atatgattcc tctatcagtc ctacttcttt
     2581 attaatttgt tttagcaaat acggatacct gtcaaaaaaa tgatttattc cgttttcttc
     2641 tcttatctgc tgtatatact gctcatatgc ctctgactta ttttcaattt ccttggaaaa
     2701 atgatttata tctaaaacta gtgttttcat cgaaaggaac atgatcgttt caaataactg
     2761 attttcaaac tcactataaa ataacttatg tgtctttttc cttaacactt cactggtttc
     2821 tctaatagaa gtatctaata tgtcatagtc aaaaattgag ttaacgtatt cgtaaaactg
     2881 atggttctga tattctaact ttaattcatc tctttttatc atttttttcc taccactact
     2941 taaaaatcct gcctagactg agtctaaaca ggaaattttt agtctgcttg tccagattgt
     3001 tttaattaac aacaaacaaa tactgagttc ggacagtcat cagtaatagt tgcaaaccaa
     3061 ccggaacctt ttttaccacc agctacttcc ataagttctt tttcagaaac ttcttcgata
     3121 gcattagtca aaatatcctt tgaattttcc ataaaactca ttctcctttc catcagtatg
     3181 tagtgactat tttctacact tttattgtaa ataatacgtc ttcattttca atgagtaaaa
     3241 agtgcaaaaa tgactttttc atatttttta gtaagatttt tgagatgtca cataagaggt
     3301 cactttataa caaatagccc tctgatataa aaaaaaacaa aactcgttct ttacagctat
     3361 tttacaatct aatcgcttct cgttataaca tcaatctcta atcagaaaat ggttacttta
     3421 cttatttaat caggtcagga gtttgaatga cagaagtcaa atatctgaaa aaggatgtta
     3481 aataaaactt tcaaaaccca ttttcatcaa ctaaaaacac ttataacccg atcttacaac
     3541 taatggatta ccatcaacag caaataatac tatgcttgaa aaatgtcaac atcatctact
     3601 ttttgtgact ataattcagt aaacgaacat gatgtgtaaa aatgtattaa aaaagtatct
     3661 caaaatcatt caatcacttg agtttctgct acttttttat accagtaggc actcttctta
     3721 ggataacgtt cttgagtctc aaaatcgata tagaagagac cgtaacgttt ttcatagcca
     3781 tttgaccatg aaaagacatc catcagtgac cacataaagt atcctttaac atttgcacca
     3841 tcagaaatag catcagaaat aacttctaag tgttttttca cataatcgat acgtccatca
     3901 tcatagacag tattatctac aaactcatct ttgtaaccaa gaccattttc agtgatataa
     3961 attttcttgt agttaggata atcagcttta acacgcatga tttggtcata tagtccttgt
     4021 gggaagataa tccagtccca gtccgttttt ggaacatcaa cgggtgcttt tcttcgacca
     4081 acacccttga tttggtattt agagctgcct ttttcccctt taccattatg aatgatttca
     4141 gtctcaccat caaaagcttg catccaatca ctcatataat agttaatacc aaggaagtca
     4201 ttcaaatctt ttgcggcgtc tagtgcagta aaatcttctt cacgaagatc aagttcacca
     4261 ccattcacct caaggatatg gttaacacct tccattgttt tatctgaata cttacctaga
     4321 taagttgcat caagaataaa tttattatgg atgatatctt ccagttcagc tgctctaaca
     4381 tcatcaagat tgttagcgtc aaatggatac ttagttggaa gagcatggac aacgccgatt
     4441 tcacctgaat aaccactatc tttaaaaagt ttgactgcac gagcatgaga gaccatcatg
     4501 ttatggtgtg attggaaaac tttagcaaga tcatattgga tacctggagg gaatttacca
     4561 actaagtatt gaccatcgcc aattggtcca atttcgttaa atgttgtcca atagttaact
     4621 tctgagaatt ctttaaaaca aaattctgca taatttacaa aatgttcaat gttctcacga
     4681 ttgaggaaat caccatccga gtggagagct tctggtgtat caaaatggtg aagtgtaaca
     4741 aaaggctcaa catgacgctt atgacactct gcaaaaagat tgtggtagta ttctactcct
     4801 ttagggttaa cttctccttt tcctgttgga aaaatacgag accaggcaat agagatacgg
     4861 atcccattaa caccaaattc ttcactaagt ttcaaatcga cagggtaacg attataaaaa
     4921 tcacttgctg gctcagctgt gtaccaatag ttgtcttcta agtatttatc ccaagctact
     4981 ggtcctttgc catctgtatg ggtagcacct tcagcttgat aagcagctgt agcaccacca
     5041 aaaataaaat ctttaggtaa tgtttttgtc atgatatacc tcttctaaat tttcatttca
     5101 ctataaagga agattgagta cccccaacct tccctagtga aatattattc ttccatctgt
     5161 tctttaacga agtccaatgc accttgacca tcgcgagtca atttgatgta ttgagcccct
     5221 tctgttttag ctaatttaat atcaagttta tcagtttcca ctttcatgtc ttcatagtta
     5281 gaagctactt gaggtgcaag gataacaagt tgatattgtg gtaaaatctc acggtgagca
     5341 ccataacttc ctgctgctgc agtgacaggt gcaccatatt ctttagctgc tttattcaaa
     5401 gcgtttgcaa gcaaaccact tgtaccacca ccggcacaaa gaacgagaac attagtttga
     5461 tcagtgattt ctttggtttc tttagctgct gatttttcaa gaatagcatc agctttttta
     5521 gtatcaaagt ttgctgctac tttttctttg aggacatctg atgaattcgt acctgctgct
     5581 tcttcagcaa gaatttgctc atcatatact ttcaagaatg ggtagtagat gatgacatca
     5641 actacgatta acaaagctgc caaaatgaat gctagcactt ggaagtttgt cccaagaata
     5701 agacctaatg gagctggtgt tgtccaaggt aagtttgcag tgaaactgtt cattccaagt
     5761 gtgtcaataa agaatttgaa aatccataca ttgacaattg gtgctaggat aaatgggata
     5821 aagaaaattg ggttcaaaac aagtggagca ccgaacaaga taggttcgtt aacaccaaag
     5881 aatgttggaa caactgatgc gcgtccaatg gctttgttac gttttgattt tgttaaccac
     5941 atgaacatga atggaacgac aagtgttgca ccagtaccac ccatggtaac gatgaacatt
     6001 tgagtccctg aagtcaagat cttatcagca tgttcaccag cttgaagtaa ttgaaggttg
     6061 gtttcagcat ttgcgtaagt aattgctgca atggctggtt caacaataga tggtccatgg
     6121 ataccaacaa accagaagag agcaaatgca ccgaagataa tagtgattcc aacataacca
     6181 tctgctgctt ggaacaatgg tgcaagaagt ttaccaattg actcggcaac gttaacgcct
     6241 aaagtactat gaacaatcaa ttcaatcaca taaagcagta caactgataa cgtaaatgga
     6301 atcaaatctt taaaaacttg agagatgttt ggtggcacct cttctggcat gcgaatagtg
     6361 acattgtttt ttacacagac tttatagaca tttacggtaa taaaagctgc gatgaaggcc
     6421 gttaacaaac cttttgttcc cataaatcca gttaagaaac caccgtcttt tgctggattt
     6481 gctgccatta gtagaaaacc tacaatagca gcaagcatgg ttgaaataaa gttgatttgg
     6541 ttagtgctag acaatgagcg gttcattgaa tcggttaatg ctttggctgt cgtaccagcc
     6601 acaaacaaac ctaaaatacc cattgagtag ttgtatggcg tcatcaagag attctcaata
     6661 tccttactcc aatggaagcc ccatgcattt ggaacatagg caatcaagat aaagatactt
     6721 gaaaacaaga taacaggcat accagcgata aaaccatcac gaatagcgcg aagatagatg
     6781 tttcgagaaa ttttctcgaa gaaaggtttc cctttctcaa tctgagcaat taatccattc
     6841 attattttgc tcctctctta taaagttcaa tcatgtgttt cattaaatct tgtaataaaa
     6901 tggtcgtcat taaatgatct tgaccatgca ttaaagtgac actataagct aagtcatctc
     6961 cagctgcttc tttttgtagt agacttgtct gagcattgtg agcatcattc aagcagtcac
     7021 tacctgcagc gattaattct tctgctttag cataatcccc ttcttgcgct gctttaagcg
     7081 cttccaaaaa ttttgaacgg gcatcaccag cataggctac gatttcaaaa cctaaaagag
     7141 tagtttcttc tctattcatt gtagtttcct ccgaaaataa tgttacattt tttcagtcca
     7201 aggacttgca gttttatcta gcactttgtt taattcgtca atatttttga aaccttctgt
     7261 acgcaaccat tcacgagctg cttgtggtcc ttcttcgata tagactttta cagatcctgc
     7321 ccaggtagca cgtccacata agacaccgtt gaatttagca cctgattctg ctgcaaacac
     7381 caaagtatct tggaacaatt tggcagaaac acctgcactc aagtaaatat atggtaaatc
     7441 agtagaagct tcttggtcac ggaaagcttg agctgcttct tcttttgtaa agagaacctc
     7501 accatctgca aagctttcta caaatttcat atttactgga acttcgactt tcaagacgtc
     7561 aacaccaaag cgttcttctg agaagacttt cattgcttca ttaactttat gagctttaac
     7621 ttttgcaaac tcagggctag cattgtcaga gattttctca tcataagtta gaatttctaa
     7681 gtagaatgga atatcttctg cacggcattc agaaccaata cgttcaatgt aagctttttt
     7741 ctgctcgttg atatcttgat ctccatcaat atcatagtaa agaaggaatt taactgcttc
     7801 tgctccagct tctttaatac gttttgcaga ccaaacatct aagcaatcag gtaagcgact
     7861 agttgttgtt gcatcgtatc ctgttttctc atatgccaac aacaagccta cttcttctga
     7921 acgaacacga cttgctggca agccatattc aggatcaagt aaaattgatg atgcaaatgg
     7981 tgttagttct tcagaaacta aacttttaag ctcttcaatt tgttctactg ttggctcttt
     8041 tgtttgatgt tgagccatca tacgtttgag agctccacgt tggtcaaaag ctaaagcaga
     8101 aataacacca tctatactta gtttttccat gcttttacgt ttgttttcag ttaaagtaat
     8161 tgtcattttt tatacctctt tgactttaat agattgatat aacttatcgt aatttgccat
     8221 gttaacatgc ccagttgttt tttcttgcgc atttaacatc cctaagacat ttgcttttgt
     8281 taataaagct cgatcatctt catcattcgc taaacctgaa gcaatacctg ccactgtaga
     8341 atcccctgaa cctacagcgc ttacaatttt gattttagga atgtcaacgt tataaaatgt
     8401 atccttgtgc tttgcaaata caccatcagc accaagagaa acgattatcc attcaattcc
     8461 ttcaaatagt tcatcttgta agacttcttt taaggcttca aaatcttttg tcatttcttt
     8521 acctaaaagt tgagaaagtt cttcaagatt aggcttgata actgttggtt tactatcacc
     8581 ttttagtact gcttctagag catttccaga acaatccaga accgttttct taccattaag
     8641 attggcaatc ttgattaact tctgatagta atcatctggc ataccagcag gcaaactgcc
     8701 tgacattgtc actacgtcaa catcattcag taaatactta aattgatgag taaatccatc
     8761 aatttcatct acacttaaca gcggtccttt ttctaaaatc tccgtttgat taccttcgtg
     8821 taaaatggct atacaagttc tagtatcacc tgaaatttta tagaagcgac ttaaaatcga
     8881 atcaggaaga tgattaatga taaaatcacc gctttctcca cctacacaac ctgtagcttt
     8941 gactgtctca ccaaagtcat ttagaactcg ggaaacattc aagcctttac caccgggtgt
     9001 ctttgtaacg tctacaactc gattgacagt atcgcatttt agctcatcca aagggtagga
     9061 gacgtcaata gctggattta aagtaactgt taaaatcaca atagctcctt tttctatata
     9121 tccttatcat aattctttca aatattagtc gtgatattca ccacggtccc atttttctag
     9181 aaattcatca aagaagtgtg ggttgttttg atcttggcta gcatgttgca agctatccat
     9241 tttttcaatc cattttttat tttcttcagt tggtttgtat tccgcggcta agaaagcatc
     9301 gataatatca ttcatcaata aaccaccgat gatttttcca ccaaaaccaa taacgtttgc
     9361 gtttagctct tcttttgagt agatagcaga tgtcatatct ctaacgagtg ctgaacgaat
     9421 tccaggaact ttgtttacgg catttgtaat accaacacca gtaccacaga taacaacacc
     9481 tagttctgct tcaccacttg ctactgcttc accaactttt ttaccaaaaa ttggatagtg
     9541 tgtgcgaaca ttatcatacg taccacaatc aataacttta tgaccttgtg attttaggta
     9601 atccacaaca gcgatttttt cataagtaac aatatggtca caacctacag caattttcat
     9661 ttttgttctc cttgttttaa cctatttcaa tcaattagca cattttatta agcatgtcga
     9721 cacgaacttg atgacgtcca ccatcatatt taccttcgac aaagcctttg ataatgttct
     9781 ttgcaattcc tggagcacta atttcagaac caagcgtgat gattcgagca ttgttgtgtc
     9841 ctcttgtcat gtatgctgaa cgctcatctg atacttcagc tgccaccatt cctttgattt
     9901 tagtagctac catgaaagaa ccaacaccat atgcatcaat gacaatacct aagttatctt
     9961 cggatgcatt aacttctttt gcaacggcta aagttgtatc tacaaagtca cgtacttcgt
    10021 tttcactaac atcaacgact tcgtgtttac cttctttaag gtaatctttg ataacttctt
    10081 taagttcttg acctgctttg tcagcaccga taataattgc cattttattt ctcctatgat
    10141 ttagaataag taaatgtgga aaacctacgt agatagttaa ttaacgattt acaacatctt
    10201 ttgaaataac gctttcatta tttctatgac ctaatcatac acccaccaaa cataaaagtc
    10261 aacatttttt tgtttatttt tataaaaaat aaacaaaata tgtttatttt tttcattttt
    10321 acgttattat cctaatgttt cttgtgtttc tttttcattt cataaatccc tttgacagcc
    10381 actcgtaacc tatcatatat tacgagaccc ttatctctat ttattgtaaa cgttttattt
    10441 aaaacatttt ctattttgtt aatttttgtt ttttccaatg tttatgtttg ttttgtttga
    10501 tttttttatt gatattatgt tatgatacct ttaatagtta taccctaaga cactgatagg
    10561 agataagaat gaaaaagaaa gagcgtcatg aaaaaattct cgatatctta aaagttgacg
    10621 gttttataaa agtaaaagat attatcgatg aaatgaacat ctcagatatg accgctagac
    10681 gagatctcga tacattggca gataaaggat tacttatcag gacccatggt ggtgctcaat
    10741 atttggatta ttcttcagca aaggacgaag gtcacgagaa aacacacact gaaaagaagg
    10801 tcttacagac taccgaaaaa aaacaaattg cacaaagagc taaaaacatt attaaagatg
    10861 gcgaaactgt ctttataggt ccagggacaa cattagagca tctagctgtc gaattgaaaa
    10921 atagaaatat cagggtcatt acaaatagcc ttcctgtttt tttaattttg cacccaagca
    10981 ctactattga tttgatttta attggtggtg aatgtcgtga aattactgga gcttttgttg
    11041 gtgctattgc cattaataat ctagaatcat taactttttc aaaggctttt gttagcgcaa
    11101 atgcagttta caataattct attgcgacgt acagtgatct cgaaggagaa gttcaaaggg
    11161 ttgcattgaa taatgctgtt gagaaaatcc ttctagttga tagtaccaag tttgaaagtt
    11221 atgacttcta taatttctac caactagatc aagtggactt aattgtgact gataaaaatg
    11281 tgacaactga tatcatagaa aagtacaaga aattctcaaa aatcataatc gctgacaagt
    11341 aaaggactta ctcatattaa aaagcacttc agggtttaga tatatcccct gtcaagtaaa
    11401 aagggagcat atctgaaagt agtgtttgta ttataaagaa gtttcttgct aacttatttt
    11461 ctggtttttt tcagacttat cagtcttgta ctgttccttt ttctgatgaa taacgtggaa
    11521 ataggcagac agctatatat ttcacctcta gaatggttgt cattactgtc atcaagacat
    11581 gcttgttctt tatcgtatgg agtgaagctt tcttttagac atcaacatac ctcttaagta
    11641 gattttggtt cgttaccatg tctacttaag aggtgtcttc aaagcgcttt aaaacgttga
    11701 tataacagta tattaacgtt ttgagaattg tgaagcttta cgagcttttt taagacctgg
    11761 tttttggttc actccattat ttaaagtcaa atccctttaa aatcaatgtt tctaaaatga
    11821 aaaatcacta aaaatcttat ttatagacaa atatttaaac ctaaacggta tcaaaaataa
    11881 gtt
//
LOCUS       DAUCXI010000046        11747 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.046, whole genome shotgun sequence.
ACCESSION   DAUCXI010000046 DAUCXI010000000
VERSION     DAUCXI010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11747
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.046"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..1713
                     /locus_tag="VGY43_001478"
     CDS             <1..1713
                     /locus_tag="VGY43_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302649.1"
                     /translation="VVFLIYFNNFFVKKRSQELGVLAILGFSKRELTKLLTLENLVIL
                     VLSYLVSLLLGPTLYFLAVLAITHLLELTLEVQWFITANEIIESLGILVVVFLINVIT
                     NGLIISKQSLIEFVNFSRKAEKKIKIRKVRAITAITAITALLLSYILCLATVFSSTRN
                     MLLSIGMVPVSLLIIVLVVLGTVFTIRYGLAFVVSLLKENKKRLYRPLSNIIYPKFNY
                     RIATKNKLLTVLGGLLTVTVSVAGMMVMLYAYSLNGIERLTPSAIEYNVESENGQVNV
                     TTILENDQVSLVDVDLLRLNTNPEVTITESGQTIPYFDIINYSDYKELMKAQGRINSI
                     EGSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTHNVFSFSTSVTTLVVSDKLY
                     AKLSSCFPEKEMTIRTFNGNSIRSSEAFYNQFSMVPDVISSYSKEYTVKTANIATYIF
                     ITFLSILFIICTGSILYFTSLIEIMENKEEYGYLSKLGYSKKMIHRILRYETGILFLI
                     PVFIGIVNGGMLLIYYKYLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVLTLRSVTS
                     IIKN"
     gene            1753..3315
                     /locus_tag="VGY43_001479"
     CDS             1753..3315
                     /locus_tag="VGY43_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEQ4302650.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILVYNRENLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYTVEITNLILYGHKQFKDKLDKGLLIIIFVSITSLFVNSILFNFLFLMVFTI
                     LHLYPLLVIVLYYRSFRQQISVVRRSLILFSLLLLVILGSELYGEMLDVNQAFNNLGW
                     YLFPLIMSVIYYFKTIHDKLSFVTQRWLGDYKARIELLFLLLILCWIVLMKVLVKDFL
                     LFFIVVDASTLFCLVVISCIFYYLKDSKQNFDYENRRLNYFMKSEENMRVEFSNYLHD
                     DVLQNIIAIKNLLSLENSNITHGFIVNELNDLVSGIRDEMDTYHPIVSANQTMKENIQ
                     SLFDDIVKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIKYGDGKDIRLSL
                     TIQSDIIIIEESNQVVEKVHSINYGRGLKSFQETLAAFDGDLELQMDTKQFTIRILLP
                     IDWKLCYEDFIN"
     gene            3296..3901
                     /locus_tag="VGY43_001480"
     CDS             3296..3901
                     /locus_tag="VGY43_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4302651.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDIILLDINLTNISKENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(4454..6034)
                     /locus_tag="VGY43_001481"
     CDS             complement(4454..6034)
                     /locus_tag="VGY43_001481"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEQ4302652.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLFAVCDNLDQHFNTFTEAQKIFEDAYQDEDLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTIANVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGREDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLEQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDNHIKKILDAYKSRDNSDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(6047..7222)
                     /locus_tag="VGY43_001482"
     CDS             complement(6047..7222)
                     /locus_tag="VGY43_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEQ4302653.1"
                     /translation="MTKSKQPQYRFDGFKGEWEEKELGDIVQITMGQSPSSQNYTTNP
                     SDYILVQGNADIKNGYVFPRVWTTQITKQADKGDIILSVRAPVGDVGKTNYHVIIGRG
                     VAAIKGNEFIFQILKYLKEIGYWKRISTGSTFDSISSSDIKYAKIQIPSLPEQEAIGE
                     LFQTVDQLIQLQDQKLATLKEQKQTFLRKMFPAQGQKVPEIRLQGFDGEWEEKKLGEI
                     SRMFSGGTPNVGIPEYYNGNIPFIRSAEINSDQTELSITDKGLSNSSAKLVEKNTLLY
                     ALYGATSGEVGLSRISGAINQAILAIIPEKKYSSLFIKNWLYKQKSSIIKKYLQGGQG
                     NLSGSIVKELTIHFPSLSEQEAIGDFFQTLDQQMSQTEDKLTELKALKQTLLNRLFV"
     gene            complement(7235..10213)
                     /locus_tag="VGY43_001483"
     CDS             complement(7235..10213)
                     /locus_tag="VGY43_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEQ4302654.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     AIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPLAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRK
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTTSAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLAHLNVV
                     FVVDECHRAVTPERQRHLTNTFRNSCWYGFTGTPIFVENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLNSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLIQKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDKALSLYSNGGENDVLAPSWEEEKARFLEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAYQAFDKLYASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRRDDDEAIPEINIDYELESIQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIVYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGMSTLKESLDYQAYKEKQGDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            10494..11636
                     /locus_tag="VGY43_001484"
                     /pseudo
     CDS             10494..11636
                     /locus_tag="VGY43_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
BASE COUNT         3613 a         1913 c         2180 g         4041 t
ORIGIN      
        1 gtggtattct taatttactt caataatttc tttgtaaaaa aacgtagtca agagcttgga
       61 gtcttagcaa tactaggatt ttcaaaaaga gaattaacaa aattactaac tttagaaaat
      121 cttgttattc tagttctgag ttacttggta agtttattgc tgggaccgac tttatatttt
      181 ttagctgtac tggcaattac tcatctattg gaattaacat tggaagttca gtggtttatt
      241 acagctaatg agattataga gtctttagga atattagttg tagtttttct gattaatgtc
      301 atcacaaatg gacttatcat tagtaaacag tctttgattg aatttgttaa tttctcaaga
      361 aaggctgaga aaaaaattaa gataagaaaa gtcagagcta ttactgctat cactgctatc
      421 actgcattgc tattgtcata tattttatgt ttggcgacag tgttttcatc cacacgaaat
      481 atgctattaa gcatagggat ggtaccggtt tctctattga taattgtctt agttgtttta
      541 ggaacagtgt tcaccatcag atatggattg gcttttgtag tttcgttgtt aaaagaaaat
      601 aaaaaaaggt tataccgtcc tctgtctaat atcatctatc ccaaatttaa ctatcgtatt
      661 gcaacaaaaa ataaattatt aacagtcttg ggaggtcttt taacagtaac cgtttcagtt
      721 gccggaatga tggtaatgct ctatgcttat tctcttaatg ggatagagag gttgactcca
      781 tctgccatag aatataatgt tgaatcagaa aacggtcaag tcaatgttac aactatttta
      841 gagaacgacc aagtgagctt ggttgatgtt gacctattga gattgaacac taacccagaa
      901 gtaactatca cagaatctgg gcaaacaatt ccttattttg atataattaa ttacagtgat
      961 tataaagagt taatgaaagc tcaagggaga ataaattcta ttgaaggtag taagtcactc
     1021 ccattgttaa taaattatta tccaacagaa attagccttg gaaaaacctt taacttagga
     1081 aatgcatatg atgttactgt aaaacaagta tcaacgcata atgtttttag tttttctaca
     1141 agtgtcacga ccttggttgt ttctgataaa ttatatgcta aacttagttc ttgttttcca
     1201 gagaaagaaa tgacaattag gacttttaat ggaaattcga ttaggtcaag tgaagcattt
     1261 tacaatcagt ttagtatggt tcctgatgtt atcagtagtt atagtaagga atacacagta
     1321 aagactgcta atattgcgac ttatatcttt ataactttcc tatccatact ctttattatt
     1381 tgtacaggta gtattctgta ctttacaagc ctcatcgaaa tcatggaaaa taaagaagaa
     1441 tatggctatc taagtaagct aggttatagt aaaaaaatga ttcatcggat tcttcgatat
     1501 gaaacaggta tacttttcct tattcctgta ttcattggga ttgtaaatgg tggtatgttg
     1561 cttatttact ataaatattt attcatggat acattggtag caggcaatat cataatgtta
     1621 tctttattgc tttgtctgct tttcttcttg ataatatatg gcacatttta tgtattgaca
     1681 ttgcggtcag tgacatccat aatcaaaaat taattttaaa aatcttttaa ctttaacgat
     1741 taagtaaata atatgataag aataaaaaac ataacaaaga gtaagttctt tgggactgca
     1801 ataatcttgt tgcaacaatt aatagccttg ttaattttgg tctataatcg agagaacctg
     1861 tctcttcttt tctctgaaaa agtagctctt gtaatgaccc ttattgatac agcttttatt
     1921 tggctggcaa caatattacg ccaaaaacaa ggtgatattt ttaaaaggat tatttctatc
     1981 atctccttaa caatttggca atacttagta tctgtgctga caagaggaac tcctctcttt
     2041 ttaagcagtg gactacagat tatattgctc tattgttata ccgttgagat tactaattta
     2101 atattatatg ggcacaaaca atttaaagat aagttagata agggcttgtt aataattatt
     2161 tttgtttcta taactagcct ttttgttaat agcattttat ttaatttttt attcctgatg
     2221 gtttttacta ttttacacct gtatccgtta ctagttatag tgctatatta taggtccttt
     2281 aggcaacaaa tatcagttgt tagacgttca ttgatactat tttctttact tttgctggta
     2341 atacttggta gtgaacttta tggagaaatg ctagatgtta atcaagcctt taataatttg
     2401 ggatggtatc tgtttcccct tataatgagt gtaatatact attttaagac catacatgat
     2461 aaattgagtt ttgttaccca aagatggtta ggtgattaca aagctcgtat agaactatta
     2521 tttctacttc ttatcctttg ttggattgta ctcatgaagg tattagttaa agattttttg
     2581 ctatttttta tagttgttga cgcaagcaca ttgttttgtc tagtggtaat ttcttgcatc
     2641 ttttattatt taaaagactc caaacaaaat tttgactatg aaaatagaag actgaactat
     2701 tttatgaaat cagaggaaaa catgagagtg gagttctcaa attatttgca tgatgatgtt
     2761 ttacaaaata tcatagcgat aaaaaacttg ctttctctag aaaatagtaa tataacacat
     2821 ggttttattg ttaatgagtt gaatgattta gtttctggta ttagagatga aatggatact
     2881 taccacccaa tagtttccgc taatcaaaca atgaaagaaa acatacagtc tctttttgat
     2941 gatattgtta aaagtagaaa aagtaatacc ctattgtatt ttaactgttc agataatatg
     3001 gtagtgccat ctccatatgg agatattgtt tataggttta taaaagagct aataaacaat
     3061 gctataaaat atggagatgg aaaagacatt cgtttatctt taacgattca atctgatatt
     3121 attatcattg aggagagcaa tcaagtagtg gaaaaagtac actctataaa ttatggtaga
     3181 ggattgaaat catttcaaga aacactagca gcttttgatg gagatctaga actacaaatg
     3241 gatactaaac aatttactat cagaatatta cttcccatag attggaaatt gtgttatgaa
     3301 gattttatta attgatgacc acagactatt tgcaaagagt atccaactgt tgttccaaca
     3361 gtatgatgaa gtagatgtca tagatacgat tacttctcat tttaacgatg taacgattga
     3421 tttgtctaag tacgatatta tattgcttga tattaattta acaaatattt ctaaagaaaa
     3481 tggattggag atagcaaaag aactcataca gtctactcct catttgaaag ttgttatgtt
     3541 gacaggatat gttaaatcaa tctatagaga gagggcaaaa aaagtaggag catacggttt
     3601 tgtagataaa aatatagacc ctaaacaact catttctatc ttaaaaaaag tggattctgg
     3661 aaaaaagtat tttgaacaaa tcgaatctca ggattatgtt gaatctttaa ctgaccagga
     3721 aatagctatc ttaaatttga gtaagaaagg attctctata aaagaaatag aggaaacgtt
     3781 acaaattagt aggagaacag tatttaatca tttgacccac atctactcaa agcttttggt
     3841 aaataataag caagaggcta tctacaaagc cgaacaatta gggtatttta tggatttctg
     3901 agttgcagat aatcaaacga cataagtttt acttgtgtcg ttgctaggga tttcctgtta
     3961 aatacccaga tttaaaatca ttgtttttta agttcttttt gattgaaatt gattgagata
     4021 acgcttttat aaaaagtagg gcaatgcctg atatgaaaag ctttttaaat ttagtcaaac
     4081 aaaagttgtt taaaccaggt ctaaaaaaac tcgtaaagct tcacaactcc cagaacgtta
     4141 atatatgctt atatatcaac gattggaact actttatggt tcgcaccatg gtttttgtgg
     4201 aaggatcaaa agttgtcctg aaaatttctc ttaaccgtgt ttaagctttc taaacgtttg
     4261 agaaatcatt gtaacttcaa ataactattt taaataaaac aaagaaacgg acaaagttag
     4321 atgagatgat tctattttga tttataggtg aagaaggaga atcttgtttg ataagtactc
     4381 aataaaggtt cactactcaa ttttaaataa aacgccacag tagtaatcat ctactgtggt
     4441 gttttttggt cttttagttt ctaaaagtat ccaattcgtc ttgtgcttct ttggttgttc
     4501 cgactagttg tttcatgagt tgatctagtt tggcatttgt tttggcaatt tcttgatcaa
     4561 tgtcactgag ctgtttagct aattctggca gtggtttaac tgggacttcc tcaaaggtat
     4621 caacatagcg tgggatattt aagttatagt cattttcaat gatttcatca aatgaggcta
     4681 aatatgaaaa cttatcagaa ttatcacgac tcttataagc atcaaggatc tttttgatat
     4741 ggttatctgt cattgtgttt tgatttttac ccttatcaaa ctcttttgaa gcatcgataa
     4801 agaagacatc tttgttggtt ctgttcttct ttaatatgat aatagtcgta gggatgcttg
     4861 tattataaaa gatatttgat gggagtccga taatggtatc gatagcccct tgttcgagta
     4921 gtttttggcg aatcttgcct tctgcagctc cacggaaaag gacaccgtgt ggtaagacaa
     4981 tcgccatagt tcctgtattt tttaaatgat agaaaccatg aagtaaaaag gcaaaatcgg
     5041 cttttgattt tggtgctaat acaccataac ttgaaaaccg tggatccgtt aagaaaccag
     5101 cagtcgctga ccatttcaaa gaataaggtg ggttcatcaa caccccatca aagttggttg
     5161 gttcatctgt tggccagtct gcatccaagg tatcagcgtt acttaagtgt tggttctcga
     5221 tggcaacgcc atgaagcatc atgttcatac gagccaagtt ataagtagaa gtattgattt
     5281 cttgaccata gtaagaaacg gtatcggatt ggttactata tttcttagca tttaaaagga
     5341 gtgatccaga tcccatagca gggtcataga gggtcattcc tttttgatct tcacgaccta
     5401 aaaagacaat ctgagtcatt aagtgagaga cagcttgtgg ggtatagaac tcacctgctt
     5461 tttttcctga ttcactggca aattcaccaa tcaagtactc ataagcatcg cctaaagtat
     5521 ccccatctac tgcctcaaag tcaatttcat ttaatgtttt catgacattg gcaatggttt
     5581 gattttgttt ttgaggagta gagcctaatt ttttagagta gaggtcaata tcttcaaata
     5641 agttttcaaa gtcttcacca ctttgttcaa tatcgcgaaa accttgagct aatgattcta
     5701 attggaaagt attgtgataa acatcttgga tgagtttttc aaaggtcagt gtcggttcga
     5761 taaagtaacc taaatcacca gtaacaacag aaatgaggtc atcttttagg tcttcatctt
     5821 gataagcatc ttcaaagatt ttttgggcct ctgtaaaggt attaaagtgt tgatctaaat
     5881 tatcacaaac agcaaagagt aatttatcag ataaatgttt gtaaaaaata agtccaagaa
     5941 gatagttttt atagtcattg gcatccattt ggccacgtaa ttgatcggcc gaatgccata
     6001 gtgcttgccg gagtgaagtt gttttctctg ccatgtgagt cctttcttat acgaataaac
     6061 gattgagtaa tgtttgtttg agtgctttga gttctgttaa tttatcttct gtttgactca
     6121 tttgttggtc taaggtttgg aagaagtcac cgatagcttc ttgttcggag agagaaggga
     6181 aatgaatagt taattcttta acaatagaac cagataaatt tccttggcca ccttgtaaat
     6241 atttcttaat aattgaggat ttttgtttat ataaccaatt ttttataaaa agagaagaat
     6301 attttttctc aggaataatg gctaaaattg cttgattaat agctccactt attcttgaaa
     6361 gtccaacctc tccactagtt gcaccgtaga gagcgtataa taatgtattt ttttccacta
     6421 attttgctga tgaatttgat agacctttgt ctgtgataga taattctgtt tgatcactgt
     6481 tgatctcagc agatctaatg aaaggaatat taccattata gtattcaggg atacctacgt
     6541 taggagtgcc acctgaaaac atccgagata tctcccccaa tttcttctct tcccactcac
     6601 catcaaaacc ttgtaaacgg atttcaggga ctttttgtcc ttgagctggg aacattttcc
     6661 tgaggaaggt ttgcttttgt tctttaaggg ttgctagctt ttgatcctgc aactgaatta
     6721 attgatcaac cgtttggaag agttcgccaa tggcttcttg ttcagggagg gagggaattt
     6781 gaattttagc atatttgata tcactagagc taatgctatc aaaagttgaa cctgtactaa
     6841 ttcttttcca ataaccaatt tctttcaagt attttaatat ttgaaagata aattcattac
     6901 cttttatagc agcaactcca cgcccaataa taacatgata atttgtcttt ccaacatcac
     6961 caactggagc cctaacacta agaataatat cacctttgtc agcttgtttt gtaatttgtg
     7021 ttgtccagac acgcggaaaa acatatccat tttttatatc ggcatttcct tgtactagaa
     7081 tataatcaga agggtttgta gtataatttt gacttgatgg agattggccc attgtaattt
     7141 gaacaatatc ccctagttct ttttcttccc actccccttt aaaaccgtca aagcgatatt
     7201 gaggctgttt agattttgtc atctctttcc tttcctagtg cccttttaag ggttggattt
     7261 gatctctaat gaattgaact aactcccgtt caaattggct cttgtatttg agtttattca
     7321 tggccgagtc accttgtttt tctttatagg cttggtagtc tagggattct tttaaggttg
     7381 acatgcccac ttgtttggta gagttagcac tatgataatt agtcgccaca aaggctaatt
     7441 tgtcaggatc tgccttccat tggtccgcaa agtgtttgat ggccctttgg atcttatcac
     7501 caatgaggtt atctaactca taaacaatgc ttttcccttc ataggctttg ggttcttttt
     7561 ggatatcttg ccataactca gctagtgagt cagccatagc agggtttgat tttgccaaat
     7621 cttggatgta ttgatccatg ggattgtcat tgagcctttc ttgaagagct tcttgttctt
     7681 gatcgacaaa ggcttgaatt aaggtcaaga tatagtgata gttgatatca tccatctgaa
     7741 tactttctag ctcatagtcg atattgatct ctgggatggc ttcgtcatca tctcttcgtt
     7801 ttcgtatttc tgcaatgaca ttttggtaag tgcctttata agtatcaatc acttcatctg
     7861 ataacccaac ttcactcaag agtgtttcat taaagtcact atagacctgt acagatgcat
     7921 agagcttatc aaatgcttga taggctttgg cgtattgttt gagaaaagct gtctgtgcgc
     7981 tctcaatagt tgggaaagcg tctggatcag gaactatatt ttttaatact gttacttttt
     8041 caaggaatct tgctttttct tcttcccaag aaggggccaa aacgtcgttt tcacccccat
     8101 tagagtagag gctaagcgct ttgtcgacag cttctttaaa acgaagtggt gtttggaaag
     8161 tcacaacctg accgtaatgt tttctacttt caaagatacg gttggttcgt gagaaagctt
     8221 gaataatgtg ctgaggtttc ataggctggc gatcaataaa gatcgttgat aaacaaggcg
     8281 catcaaaacc tgttaagaga cggtcaacca caatcacgag gtctaattgt tcatgacggt
     8341 ctttgaattt atctttttta cgggctaagc gatcatttaa atctctgtta tagccttgta
     8401 agttatcgat ggtaaagtta gtgccaaaga ggtgattata gtcttctaga tttttggtca
     8461 ttttatcttg tcggctgata gacgcattgt cattttcagt gatagaataa gtaatagcta
     8521 cctttggaaa gtctggtagt ttttctttga ccttcttaga aatgactaaa tccgtttcac
     8581 cagctttaac tttctgaatc agatcataat aggcttgggc acgagcaata ctcttaacgg
     8641 ttaataagcc ttcgaatgtc tgaccaatcc cattattaaa gccaagcttc ttacgtgatt
     8701 gattaatgat actatttaag acagctaaca tatgttcttc atgatcataa gcttcttcag
     8761 gaatactgtc ttcaggcata tcaggaatgg ttgtcttata ctcaacttgg aagcctagaa
     8821 ccgctttatc gtgaatggct tctttgacag tgtattgatg gagacatttg ccgtattgct
     8881 gttccgttgt ttgggctaaa tcacctaatt gagcacgctt attttccaca aagataggag
     8941 tacctgtaaa gccataccag caactgtttc gaaaagtatt cgtgagatga cgctgccgtt
     9001 ctggcgtgac agcacggtgg cattcgtcta caacaaagac gacatttagg tgtgcaagac
     9061 gctcttttag tttcttgaat tttggagtgt cataactttc catctgactg atcatagcat
     9121 tgagtttttg aatggtggtg accacaacac gacgatcact ggattctaaa tttttgatga
     9181 gttgtctcgt atcttctgtc tcatcgacat caaagatatc attttgcgca taagattgaa
     9241 aagcagaagt ggtctgatta tctaaatcct ttcggtcaat gacaaagatg gatttttcaa
     9301 cggccggtat ttgaaggata ttgcgagcca ctttatagga agttaaggtt tttccagaac
     9361 ctgttgtgtg ccagatatag ccagacttgc ggtgacgact cgcttcagcg acggcttcga
     9421 ttgcatgaat ctgataagga cgaaggagaa ttagtgcttt tttatcatca tcaatgacag
     9481 agtaagtcat gaccatttgg tgagcaagag ggatagatag gacttctttg gcaaaagcaa
     9541 agagatcttt ttgtggtttg ttgttttgat ctacccattg ggtcaagaag ttaggattta
     9601 atttattttc tttagctgca gcgatatacc ttgtatctgt tttatttgag accacaaaca
     9661 tttgtaaggt tgaaaagata cctctaaact ggccttcttt atcatacttt ttgacttggt
     9721 taaaagcttc aatgcattga tgattctgag attttaattc aatttggatc ataggtaagc
     9781 cattgatgag aagtgtcaca tcacctcgtc tatcacgaga accagagaaa gcaacttgat
     9841 tggcaatctc ataaacagaa gttccaccag ccacattgtc tgctttaacg acttctaaac
     9901 gaatcgctcc tagttttgca tcttcgcgtt gcacttgtac tttagcaatg ccgttttcac
     9961 cagctaacca tttagccgct tcatagtaat tgacaaagtt aagttgattc ttaatctgct
    10021 ctttttcact agctgttaaa ggctcctcat tcagatattg cgtgttattt tgcgctaaga
    10081 tcttaaagaa attatcccat aaagcatctt cagtttttaa ttctttacga tatgtccatt
    10141 gactttcacc tgtttctaag agatggatca actctttttc aagttcaagt tccgttttag
    10201 tttgatttcc catttttaat ccccattcga catgatatag tagtattata tcattggcgg
    10261 atccttttta gaatggcaaa gctattgaaa ccttccaaac agtctttttt tgattagttg
    10321 aatgcttaag atcctagcaa ctaaacaaag ctatgactat gtaaatgcaa tcgagaaagt
    10381 tcttgtattt ttgagtttgc ttgacaataa tttaaggtga agaaagtaat aagacaacac
    10441 tagtaaaaag gtcgagttct caaaatagat aaaaaactta agacagatct agcttgacta
    10501 ttaatagggt tttaaaggac gataatctgc tacaatatac agaaaaggaa tttattgaag
    10561 atatgaaaat tttggtagcc atagattctt ttaagggatc ggtaacgtct tcagaactta
    10621 acactagtgt agctcaagcc cttctttctg tcgataagca gttagttatt gaagcaagag
    10681 ctatcgctga tggagaagaa ggaagtttag cagccctctc acaaaccgtg gcggggaggt
    10741 ggcatcaagt aaaaaccgtt gatctattaa gacgcccgat taaagtcgct tattatcgtc
    10801 acgcaaagca agcttttatt gaatctgcga gtattattgg tattgatagg atcaccccca
    10861 gttcagtaac ctatgcacaa gccacttcct acggtttggg tttggcagtt aaagatgcca
    10921 ttcaaaaagg agctactcaa atcgaaatca tgctaggagg aacaggcact tctgatggtg
    10981 gcaaagggtt tttagaaagt ttaaactatg atttcatgac aggaagatct tatcttgata
    11041 ctttagcatc acctgttacg ctattaggtc tgactgatgt aaccaatcca tatcatggcc
    11101 ctcaaggatt tgctgcggtc tttggccctc aaaaaggtgg gagtcttagt caaattgaag
    11161 aaacagatca aattgcaagt aactttgcta aaaaagtttt ttaccaaaca accattgatt
    11221 tacagacaat accaggaagt ggagcagctg gaggattagg aggtgccatt gtcctattag
    11281 gaggcacctt aactagtggt tttagcagga ttgcagagct actaaatctg gataattccc
    11341 ttcagtcttg tgatttagtt attactggag aaggatgcct ggatacacaa tcacaatctg
    11401 gcaaggtacc tgttgcgatt gcaagaatgg ctaaaaaata ttaagttcca acgattgctc
    11461 tatgcggttc tgtaaagatt gagacaggac tagcagcaga agactttttg gctgtttttt
    11521 caatacaaca gcagccaatt tccttagaag cagcgataga taaaataaca acactttcta
    11581 atatcaaaat attagcagct aaccttatgc tattgatagc tcagtttaat aagtaaactc
    11641 atctattttc gattgtgtag cattcatttg gcggttaaaa gtaacctatg aagaaggaga
    11701 cgcacgagct aactcattag catagtatga aaaacagaaa cattttg
//
LOCUS       DAUCXI010000047        11373 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.047, whole genome shotgun sequence.
ACCESSION   DAUCXI010000047 DAUCXI010000000
VERSION     DAUCXI010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11373
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.047"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..321
                     /locus_tag="VGY43_001485"
     CDS             <1..321
                     /locus_tag="VGY43_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ4302655.1"
                     /translation="ILVGGQSDPIDITEDTQPGMSGSNDATVIEEDTKPKRFFHFDNE
                     PQAPEKPKEQPSLSLPQAPVYKAAHHLPASGDKREASFTIVALTIIGAAGLLSKKRRD
                     TEEN"
     gene            501..2432
                     /locus_tag="VGY43_001486"
     CDS             501..2432
                     /locus_tag="VGY43_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ4302656.1"
                     /translation="MTKKFIKSAMILGLASITISMTQPVEAIANRLEYQAQYERVKEE
                     LDALKATSPKLGERSLYFRLVNRFLGWFGVVWDPLAIKETDHLLDLIGQVNYLVSNTE
                     FQAPEYKHAKNKLDLAVAGYELYLAREKERGDTPDYQVTQLTFKQLETIKTKIREALE
                     TFAQEVKTIQQKNPDLFPHAYVLNAKTSAIDGKAQPFLVNGYYDVFYKQFLFTNKNDG
                     YNYNKEADNLTLYQDLIKELLGLKAEIDRLTKDKTDDSRLETLMWESKFTLSDFRRTS
                     RLSAYYTQEDYVKKVVLSEEAPNLRTAKEKVKTLKGILHDYYVDIKEPEKAKQYHVED
                     ETSPSQPEAPAPGQKPAEDEGSSQATEPANPSKEDSSTDASQGSHDSENPATDNPSQP
                     QVPDQGNHQSQVPNDKPQTDKTDTPNVPASPQDTPNAPAPPQDTPKVLEAGGQSGPAG
                     NAEEKAPDSGPKESGQSSSKESPSVGEDTTPNQPDVLVGGQSEPNDITEDTITDAPPT
                     VSGHNASTQPQSVVEDTAPQRPDVLIGGQSEPIDITQDTQPGMSGSNDATVINEDTKP
                     KRVFHFGNKEPQASEKATEQPAVPHDSHTTPQASDDTAAPHLPASGDKPEKVFALAAL
                     TMVAAAGLLSKKRRNTDKN"
     gene            2565..2861
                     /locus_tag="VGY43_001487"
     CDS             2565..2861
                     /locus_tag="VGY43_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HEQ4302657.1"
                     /translation="MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM"
     gene            3008..3292
                     /locus_tag="VGY43_001488"
     CDS             3008..3292
                     /locus_tag="VGY43_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEQ4302658.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            3716..4984
                     /locus_tag="VGY43_001489"
     CDS             3716..4984
                     /locus_tag="VGY43_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEQ4302659.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            4971..5645
                     /locus_tag="VGY43_001490"
     CDS             4971..5645
                     /locus_tag="VGY43_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302660.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            5658..6875
                     /locus_tag="VGY43_001491"
     CDS             5658..6875
                     /locus_tag="VGY43_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302661.1"
                     /translation="MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            6969..7622
                     /locus_tag="VGY43_001492"
     CDS             6969..7622
                     /locus_tag="VGY43_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4302662.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            7619..9007
                     /locus_tag="VGY43_001493"
     CDS             7619..9007
                     /locus_tag="VGY43_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ4302663.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKR
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLI
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            9109..10737
                     /locus_tag="VGY43_001494"
     CDS             9109..10737
                     /locus_tag="VGY43_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ4302664.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNNPSSTDQPTTAD
                     TDTDDESETAKKDKKSKETASQHDTQKDHKPSHNHPTPPSNDTKQTDQASSEATDKPN
                     KDKNDTKQPDSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKT
                     PEKGPEKATEKTPEPNRDAPKPIQPPLAAAAPVFGLWRESDKDLSKLKPSSRSSAAYV
                     RHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVR
                     AIVAIAMAESSLGTQGVAKEKGANMFGYGALDFNPNNAKKYSDEVAIRHMVEDTIIAN
                     KNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTP
                     EIPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVD
                     RYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILIS
                     ESNVMGLGTISYRTFTAEQASLLTYVVGDKLPRP"
     gene            10815..11066
                     /locus_tag="VGY43_001495"
     CDS             10815..11066
                     /locus_tag="VGY43_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302665.1"
                     /translation="MIKKVTTPSQKTKKRVRNGYLLKVGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
BASE COUNT         3973 a         2384 c         2270 g         2746 t
ORIGIN      
        1 atccttgttg gcggtcaaag tgatccaatc gatattaccg aagataccca accaggcatg
       61 tcaggctcaa atgacgctac tgttatcgaa gaagatacga aaccaaaacg cttcttccac
      121 tttgataacg agccacaagc accagaaaaa cctaaagagc aaccatctct cagcttacca
      181 caagctccag tctataaggc agctcatcac ttgcctgcat ctggagacaa acgtgaagca
      241 tcctttacaa ttgttgctct aacaattatt ggagctgcag gtttgctcag caaaaaacgt
      301 cgcgacaccg aagaaaacta accctcgtta gtctagcgac tctaagcctt tggctttaaa
      361 aatttctcat tatccccctc aaacaccggt tcctcactga gatggcgctt taaaaaggcg
      421 ctagtctcaa atcaggtatc ccctacggtt gagggggatt aatgggtatc acaacaagta
      481 aaaaggtata atgatgaaat atgactaaaa aatttattaa atcagcaatg attctaggct
      541 tagcaagcat aaccatcagc atgacgcaac ccgttgaagc cattgcaaat cgcttagaat
      601 atcaagcaca atacgaacgt gtcaaagaag aactagacgc attaaaagca acaagtccaa
      661 aattaggaga acgttccctt tattttagat tggtgaatag atttctaggt tggtttggcg
      721 tagtctggga cccactcgca atcaaagaaa ccgatcacct gttggacctc atcggacaag
      781 tcaattactt ggtgagtaac accgagtttc aagcccctga atacaaacat gctaaaaaca
      841 aactagactt agctgtagca ggctatgagc tctacctagc tagagaaaaa gaacgtggtg
      901 atactcctga ttaccaagtg acccagctaa cgttcaaaca gctcgaaacc attaaaacga
      961 agatacgaga ggccctggaa acatttgcac aagaggtcaa aacaatccaa caaaaaaacc
     1021 cagacctatt tccccatgct tatgttttaa acgctaagac cagtgctatc gatggtaaag
     1081 cgcaaccctt tttagtgaat ggttactacg atgtctttta taagcagttt ttattcacta
     1141 ataaaaatga cgggtataac tataataaag aagcagacaa cctaaccttg tatcaagatc
     1201 tgattaaaga gctattaggc ttaaaagctg agatcgatcg gttaacaaaa gacaagactg
     1261 atgatagccg tttagagacg ttaatgtggg aatcaaagtt caccttatct gactttcgga
     1321 gaacttcacg ccttagcgcc tactatacac aagaagatta tgtcaaaaag gtggtcctat
     1381 ctgaagaagc tcccaacttg agaacagcaa aagaaaaggt caagacctta aaagggatct
     1441 tgcatgatta ctatgttgac attaaagagc cagaaaaagc taaacagtat catgtcgagg
     1501 acgaaacctc accgtctcaa cctgaggccc ctgctcctgg tcaaaaacca gcagaagatg
     1561 agggatcgtc acaagctacg gagccagcta acccgtcaaa agaggattcc tcaacggacg
     1621 catctcaggg atctcacgat agtgaaaacc cagcgacgga taatccttct caacctcagg
     1681 taccagacca aggcaatcac caaagccaag tgcctaacga caagcctcaa acggacaaga
     1741 cggacactcc taacgtccca gcctctccac aggacactcc taacgcccca gcccctccac
     1801 aggacacccc aaaagtgctt gaggctggtg gtcagagtgg ccccgctggg aacgctgagg
     1861 agaaagctcc tgactctgga cctaaagagt ctggtcaaag ctcatctaaa gagtccccat
     1921 ccgttggcga agacacgacc cctaatcagc cagacgtcct tgtaggtggt caaagtgagc
     1981 caaacgacat caccgaagac acaatcactg acgctcctcc gacagtatct gggcacaacg
     2041 catcaacaca gccccaatct gtggtcgaag acacagcacc tcagcgccca gatgtcctta
     2101 taggtggtca aagcgagcca atcgatatca cccaagatac ccaaccgggc atgtcaggct
     2161 ctaatgacgc taccgttatc aatgaagata caaaaccaaa acgcgtcttc cactttggta
     2221 acaaagagcc acaagcatca gaaaaagcga cagaacaacc tgccgttcct catgatagcc
     2281 acacaacccc tcaagcttca gatgatacag cagcccctca cttgcctgca tctggagaca
     2341 agcctgaaaa agtgtttgca cttgctgcct tgacaatggt cgcagctgca gggctactca
     2401 gcaaaaaacg tcgcaacacc gacaaaaact agtcgctgtt aggcacaacg catcactaag
     2461 gccagtgcaa atgcactggc cttagttagg tttttatcaa atttcatgac aattgctagc
     2521 gtttcagtgt aaaataaagg taataaccag caaaggagca acccatgaca aagcaagatc
     2581 agttaatcgt tgaaaaaatg gaacaaacct atgaggcctt tagcccaaag ctagcaaatc
     2641 tcatagaagc cctagatgcc tttaaagagc attatgagga atatgccaca cttagaaatt
     2701 tttacagtag tgacgaatgg tttcggcttg caaaccaacc ttgggatgat atcccgtgcg
     2761 gtgtcctatc tgaagacctc ctctttgata tgatcggtga ccataaccaa ctactagctg
     2821 atatcttaga cttggcccct atcatgtaca agcatatgta accattgtta acgtcacaga
     2881 tactacgatg acaggacaaa aaaagcttga aaatctcaaa aaaacagata aaaaacagat
     2941 aatcgttaga aaaacagtag atgcgtctgt taaactaaag gtatcaaaac aaaaggagca
     3001 tttcatcatg aaattcaaaa aagtattagt cattcctgca ttagcattag cagcaacatg
     3061 ctttttaaca gcttgtggca caaaaaaaga ttctaaaaaa gaagaagtta aagaaatcaa
     3121 aatgtctgac atcaaagacg acgcagttag caaaaaaaca aaagtggttg atggcgaaga
     3181 agttacagaa tacaccacaa aagatggaaa cgtgattcag attcctgcag gaaacgaaga
     3241 aggcatggaa tcaaaagatg ctggtggatc aggcgctcct gctaaaaact aagggttaca
     3301 acaaagagca taaggtgact cgcaaacgtt acgcatgaca tgaggcagtc tgcctaagat
     3361 gataactcac ttatcataat gcctaaatag ccaaacacac taactcgcaa atgtacaaaa
     3421 tcatataccc gtgcttatgt gagcgaacgg ttatatgatt tttgttttcc aaaaacaaga
     3481 aaagaacgct aaaatagcca gtttgtcgtg tttcaagcta ccaaaaagga agtgctaaaa
     3541 tgaaaaaaag gtccattata cctgtcatct tactgttggt catcggatta atcgttggtg
     3601 ttaagcgtca tcatgactag taggtcttgc tagtgaccgt tcaaaaggga taacgtgggt
     3661 atggtataac cataaaaatc gtataaaaag aaaaaatagc tattgaggag aaagtatgtt
     3721 tcagttaaga aaaaaaatga cgcgcaaaca attagccttg ttgagtgctg gagtgttgac
     3781 ctgtgtggtt ggtggtagct acttgataat gaaccatcaa caacaagaaa ttgtctccag
     3841 tgtcaacaaa gtaaaagcct taaccataaa agaagccatg gaacaaggaa aagatatcag
     3901 cttgacctta gctggtgaag taacagctaa caacagcagc aaagtcaaaa tcgactcaag
     3961 taaaggagaa gtcaaagatg tctttgtcaa aaaaggcgat gttgtcaaag taggacaacc
     4021 cttgtttagc tatgaaacgt cacagcggtt aacggctcaa agttcagaat ttgatgttca
     4081 aaccaaagcc aatcaactcc aagttgctaa aaccaatgca gcattgaagt gggaaaccta
     4141 caatcgcaag gtcaatgaaa tcaacaccct aaaatctcgc tacaacactg caccagatga
     4201 gagcttacta gagcaaattc gcagcgcaga agacagtgtc tctcaagcac taagcgatgc
     4261 caaaacagca gatagcgatg tcaaaaccgc tcaaatagaa ctcgataaag ctaatgctac
     4321 tgccacaacg gaaaaaggta aactagagta tgacaccgtt aagtcagaca ccgcaggaac
     4381 cattgttagc ctaaatactg atttgccaaa tcaatcaaaa tccaaaaaag aaaatgaaac
     4441 ttttatggaa attatcgaca aatcaaaaat gttagtcaaa ggtaacatca gtgaatttga
     4501 ccgtgacaag ttaaaaatcg gtcaaaaagt cgaagtgatt gaccgcaaag acaactctaa
     4561 aaaatggact ggaaaagtaa cccaagttgg caacctcaaa gcagaggaaa aaggccaagg
     4621 tcaaggccaa ggtggcaatg accaacaaga caatccaaac caagcaaaat tcccttatgt
     4681 tattgaactt gaccaatcag acaagcagcc actcattggc tcacacactt atgttaatgt
     4741 gctcaacaat gttccagaag ctggcaagat cgtattgaaa gaaaccttta caatggcaga
     4801 aaatggaaaa acctatgtgt ggaaagttga taaaaacaag gtcaaaaaac aagaaatcaa
     4861 gactaagcca ttctcaaaag gttatgttga ggtgacaagt ggcttgacta tgcaagataa
     4921 gattgctcag ccgcttcctg gcatgaaaga cggtatggag gtaggaagta ttgttaaacc
     4981 ttaaagatat tcgaaaaagc tatcatcttg ggactgaaga atttgcgatt ttaaaaggaa
     5041 tcgatttaga agttaacgag ggtgactttt tagccatcat gggaccatca ggttcgggaa
     5101 agtcaacatt gatgaatatc attgggtgtt tagataagcc tggctctggc tcatatgcca
     5161 ttgaaggcag agacgtgtca tccttatctg ataatgaact tgctgatttg cgcaatcaaa
     5221 aaatcggctt tgtttttcaa aactttaacc tgatgcccaa gctaacagct tgtcaaaatg
     5281 tcgaattgcc cttgacttat atgaatgttc ctaaaaaaga gcgtcgcaaa cgagccctag
     5341 agatgttaaa gctagtagga ttagaagaac gtagtgaatt taaaccgatg gagctatctg
     5401 gtgggcaaaa acagcgtgta gcgattgcaa gagctttagt cactaacccg agttttatcc
     5461 ttggtgatga gccaacaggt gcactagaca caaaaaccag cgtccaaatc atggacctat
     5521 ttaaacaatt caatgataac ggcaaaacga ttattatcat cacacacgag cctgaagtag
     5581 ctgccttatg caaaaagacg gtgatcctaa gagatggtaa tatagaacat tccgatatag
     5641 agtaaagggg gaaaataatg gaagatatta ttgcagcttt aagctctata ttatcacaca
     5701 agatgcggtc aattttgaca atgctaggga ttattatcgg tattggtgcc attatcgcaa
     5761 tcttttcaat catcgaaggt aataccgaaa ataccaaaag acagttgatt ggtggcagca
     5821 ataacactat taacattgtg tttaacaaaa aaagcagtat tgaccctaaa tttccagaca
     5881 agtcaaatgc taaaaaacca gactatcttc cttttatggc tgaagaagag cttagcaaaa
     5941 tacagcaagt caaaggtgtc aaaaacgccc tgatctcata tggtattgat gacaaagtct
     6001 accatctagg ccaaaaatca tctgcaaaga tttctgccat cacaaaaaac gtagctgaag
     6061 tgaggcgcat gacatttatt aaaggcagtg acttttcaga caaagacttt attgaccaaa
     6121 aacaggtgat ttaccttgaa aaaagcttgt atgagtcact atttccaaaa gacgatggcc
     6181 ttggaaaatt tgtcgaagtg atgggaaatc ccttcagggt cattggggtg tttgaatcaa
     6241 aagaacaaag tggcctcaca agtgggactg agaaaattgc ttatatcccg ctacatcagt
     6301 ggtataatat taatggtgta gtggatgcga cacctgagat cacgatccag acctatcgcg
     6361 cagatgacct caagcctgta gcaaagcgtg tcagtgatat gcttaatcaa acgatcccta
     6421 aatcagatta tatgtttggt gtcatgaacc ttaaagaatt tgaacgccaa ctagacaacc
     6481 taaacaaatc taattttgtg ttattagctg gtattgctag tatctctctt attgtaggtg
     6541 gtattggtgt gatgaacatt atgctagtat cagttaccga aagaacgaga gaaattggga
     6601 tcaaaaaagc gcttggcgct agacgtaagc ttattttaaa acaattttta attgaagcgg
     6661 tcattctaac cttgctaggt ggtgtgatag gggttatttc agggatggta tcaggattga
     6721 tcatcacaag atcactcgag tatccctata tcctatcctt gttctcagtt gtcttgagtt
     6781 tagcgttttg ttgtattata gggattgtct ttggactatt accagccatt aaagcgtcta
     6841 agctagaccc aattgaagca ttgcgatttg aataatcaac caaacaagca taaaagtcaa
     6901 aaaggatgac cctttgatgt catccttagc tgcttgatac actaaacgcc aatctagaaa
     6961 gggaagttat gtttaaaata ttagtagttg aagatgatga taccatcagt caagtgattt
     7021 gtgagttttt aaaagcgaat aactatgatc cagattgtgt atttgatggc caagctgcct
     7081 tagataagtg gcagacaacg tcttatgatc tgattatttt agacatcatg ctcccttcct
     7141 taagtggctt agaagtgcta aaaacaattc gaaagacatc agatgtccct attattatgc
     7201 taacggcatt agatgacgag tacacacagc ttgtaagctt caaccatttg attagtgatt
     7261 atgtgaccaa accattttca ccactcattt taatcaaacg tatcgaaaat gtattacgcg
     7321 tctctactcc agatgaaaag cgccaaatcg gagacttact tgttgatgag accgaacata
     7381 gcgtctattg gcaaggaaca ttggtcaaac taaccaaaaa agaatatgac attattgatt
     7441 atttagcaaa acgtcaccaa aagattgtca ccagagacca attgatggat gacatatggg
     7501 gctattctga actggacacg cgtgtccttg acaaccacat caagaacctt cgtaaaaaaa
     7561 tgacgggtat tcccctcaag acaattacag gcatgggcta tttattggga gagcgtgagt
     7621 gagactaatc aaaaaaacct ttttggtcat caatggctta attattgtag tggttacctc
     7681 tattttgtta gtgctttatt ttgcaatgcc aatttattac accaaagtca aagacaaaga
     7741 agttaagcgt gaatttgacc aaacaagcaa gcaaatcaaa ggcaaaacgg taaccgagat
     7801 tagagatatc ctaacaaaaa aaatcaacaa agataatatt tggtacagct tagtagacag
     7861 tgataaccaa ctgctctatc cttccttgca gctcctagac ggcgtcagtg aaagcaaaga
     7921 cagtcaaaat gttaatatcg tcaccacctt tgacaactct tattctaatg ttaaggtgat
     7981 gagtcaaaaa gtaaccctac gcgatggaaa aaaaatgaca ttgcttgggc aatcttcact
     8041 tcaacccgta acagatgcta gcaaagttct ccttgacctc tacccgtcac tattgatttt
     8101 ttcagtgacc gtagggagta ttgtcgccta cttatatagt aggacttcta gccggcgtat
     8161 ccttagcatg tcacaaaccg ccaaaaaaat ggtcaaccta gaaccaaact taacgtgtac
     8221 cattcacggc aaagatgaaa tagcaatgtt ggctagtgat attaaccgtt tgtatgcgag
     8281 tctttcaacg agcatcaaat ccttgcaaaa agagtatgaa aaagcttctg attcagaaag
     8341 agagaaatct gagtttttac gcatgacatc gcacgagcta aagacaccaa tcactagtgt
     8401 tatcggaatg attgatggaa tgctctataa tgttggtgac tttgcagatc gtgacaaata
     8461 tttgcgaaaa tgccgagacg tccttgaagg gcaagcccaa ctggttcaat ccattttatc
     8521 tttatctaag attgaaaccc tagcttctca aaatcaagaa ctgttttcac taaaaagcag
     8581 cctagaagaa gaaatggaag tctttctcgt tttatcagaa ctaaaacacc tcaaagtgac
     8641 tatcaatctc gaagaacaat tcgtcaaagc caataaagta tacctactaa aggcgattaa
     8701 aaatattatt gacaatgcct ttcactatac caaatcaggc ggccaagtga tgattcaact
     8761 aaaagacaac caactagtga ttaaaaatga agcagagaca ttattgacac aacagcagat
     8821 gaaacagtta ttccaaccgt tttatcgacc agattatagt cgtaacagga aagacggtgg
     8881 tacaggattg gggctgttta ttacccacca gattcttgat cagcatcatc tggcttatcg
     8941 ctttgttgtt cttgatcaaa gatggatggt atttacgatt gattttccat cccatcatga
     9001 cgattgatcc acactagtag gacgacaaaa gtcatcaatc attaaccaag ccttgacctt
     9061 tacccatcat tgtttaggca agtataaaaa agaggagaga aatcatatat gaagaaaagg
     9121 aaattgttag cagtaacact attaagtacc atactcttaa acagtgcagt gccattagtt
     9181 gttgctgaca cctccttgcg taataaccca tcatccactg atcagcctac tacagcagat
     9241 actgatacgg atgacgagag tgaaacagca aaaaaagaca aaaaaagcaa ggaaacagcg
     9301 tcgcagcacg acacccaaaa agaccataag ccatcacaca atcacccaac ccccccttca
     9361 aatgatacta agcagaccga tcaggcatca tctgaagcta ctgacaaacc aaataaagac
     9421 aaaaacgaca ccaagcaacc agacagcagt gatcaatcca ccccatctcc caaagaccag
     9481 tcgtctcaaa aagagtcaca aaacaaagat ggccgaccta ccccatcacc tgatcagcaa
     9541 aaagatcaga cacctgataa aacaccagaa aaatcagctg ataaaacccc tgaaaaagga
     9601 ccagaaaaag caactgaaaa aactccagag ccaaatcgtg acgctccaaa acccatccaa
     9661 cctcctttag cagcagcagc tcctgtcttt ggactttgga gagaaagtga caaagacctg
     9721 agcaagctaa aaccaagcag ccgctcatca gccgcttacg tgagacactg gacaggtgac
     9781 tctgcctaca ctcacaacct gttgtcacgc cgttatggga ttactgctga acagctagat
     9841 ggttttttga acagtctagg tattcactat gataaagaac gcttaaacgg aaagcgttta
     9901 ttagaatggg aaaaactaac aggactagac gttcgagcta tcgtagctat tgcaatggca
     9961 gaaagctcac taggtactca gggagttgct aaagaaaaag gggccaatat gtttggttat
    10021 ggtgcccttg acttcaaccc aaacaatgcc aaaaaataca gcgatgaggt tgctattcgt
    10081 cacatggtag aagacaccat cattgccaac aaaaaccaaa cctttgaaag acaagacctc
    10141 aaagcaaaaa aatggtcact aggccagttg gataccttga ttgatggtgg ggtttacttt
    10201 acagatacaa gtggcagtgg gcaaagacga gcagatatca tgaccaaact agaccaatgg
    10261 atagatgatc atggaagcac acctgagatt ccagaacatc tcaagataac ttccgggaca
    10321 caatttagcg aagtgcccgt aggttataaa agaagtcagc cacaaaacgt tttgacctac
    10381 aagtcagaga cctacagctt tggccaatgc acttggtacg cctataatcg tgtcaaagag
    10441 ctaggttatc aagtcgacag gtacatgggt aacggtggcg actggcagcg caagccaggc
    10501 tttgtgacca cccataaacc taaagtgggc tatgtcgtct catttgcacc aggccaagca
    10561 ggagcagatg caacctatgg tcacgtcgct gtcgtagagc aaatcaaaga agatggttcc
    10621 atcttgattt cagagtcaaa tgttatggga ttaggcacca tttcctatcg gacgttcaca
    10681 gctgagcagg ctagtttgtt gacctatgtc gtaggggaca aactcccaag accataaccc
    10741 cacaaccaag aagctacctg cctgttgacc aatctcaaaa agagatagcg tcaacttaga
    10801 atgaggttca tcagatgata aagaaagtga ccaccccgag tcaaaaaaca aaaaaacgtg
    10861 ttcgtaatgg atacctccta aaagtaggta cagcctgttt actcttaagt atactcagtt
    10921 atggcattgg tcttttgggc cagcctagca tggaaaatac gtttatggga atagcgagtg
    10981 ttgccatgtt aggaagtgtc tgtttcttta ttatctttgc tctaaaccgt atctttgacg
    11041 cactagagga caatttgcga gattagagta ataggtcaaa taatcttcca ataatttaga
    11101 gcacaagcta agttattgga agtttttttg tcttttgaga gccatgatgc catcaaaaag
    11161 ccaaacactc cttatgatgt gagagtcaca tgactaaaat taaaagcaaa atagacccca
    11221 aagccctgtt ttctcaaaac agtcaacgaa aaaagacaag ttaaccagtt cataaaaaac
    11281 atcgtagaaa cattttcaag agctaatgtt ggtgtaaatt gactgaagta tgatagaatt
    11341 tttaatgaat gtgacaataa tgtcacagat aag
//
LOCUS       DAUCXI010000048        11193 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.048, whole genome shotgun sequence.
ACCESSION   DAUCXI010000048 DAUCXI010000000
VERSION     DAUCXI010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11193
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.048"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            125..1369
                     /locus_tag="VGY43_001496"
     CDS             125..1369
                     /locus_tag="VGY43_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ4302666.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFAHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAI
                     KMGRFSEQLIKKTRSMLLNNALLSEDYNKNIIERIYTSSYIDSSYSIKNWIKGVNEVN
                     KADIIKVANLLKLQTVYFLEGI"
     gene            1371..2660
                     /locus_tag="VGY43_001497"
     CDS             1371..2660
                     /locus_tag="VGY43_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEQ4302667.1"
                     /translation="MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTV
                     GFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQ
                     TSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGI
                     LQNLFPKTSLANDIAGSKASIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLA
                     IQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLT
                     YRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAM
                     SNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKET
                     YFDIPKIIERLTLKDVVTIGKAFFEKADASDFTVFPK"
     gene            2710..3735
                     /locus_tag="VGY43_001498"
     CDS             2710..3735
                     /locus_tag="VGY43_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ4302668.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYRYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGYGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     NVSRMRRNSTDSRSKTSLFPIVILGTIAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTKGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            3749..4291
                     /gene="pgsA"
                     /locus_tag="VGY43_001499"
     CDS             3749..4291
                     /gene="pgsA"
                     /locus_tag="VGY43_001499"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEQ4302669.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVASNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMPGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            4293..5132
                     /locus_tag="VGY43_001500"
     CDS             4293..5132
                     /locus_tag="VGY43_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ4302670.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPVDYGYLTEKELENQLCQLI
                     SKM"
     gene            5108..5950
                     /locus_tag="VGY43_001501"
     CDS             5108..5950
                     /locus_tag="VGY43_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEQ4302671.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELREV
                     LKHG"
     gene            5943..6743
                     /locus_tag="VGY43_001502"
     CDS             5943..6743
                     /locus_tag="VGY43_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEQ4302672.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
     gene            7115..7729
                     /locus_tag="VGY43_001503"
     CDS             7115..7729
                     /locus_tag="VGY43_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HEQ4302673.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKVPKNNHAITKEESKEKAKSIASEPIPTVENSVAPTVTEEAPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     ATNASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
     gene            complement(8143..9015)
                     /gene="sdaAA"
                     /locus_tag="VGY43_001504"
     CDS             complement(8143..9015)
                     /gene="sdaAA"
                     /locus_tag="VGY43_001504"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEQ4302674.1"
                     /translation="MFYTIEELVKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDNYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKKQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIESQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
     gene            complement(9027..9698)
                     /gene="sdaAB"
                     /locus_tag="VGY43_001505"
     CDS             complement(9027..9698)
                     /gene="sdaAB"
                     /locus_tag="VGY43_001505"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEQ4302675.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
     gene            9996..11117
                     /gene="mnmA"
                     /locus_tag="VGY43_001506"
     CDS             9996..11117
                     /gene="mnmA"
                     /locus_tag="VGY43_001506"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEQ4302676.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVTVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
BASE COUNT         3672 a         1840 c         2066 g         3615 t
ORIGIN      
        1 tgtagaaaac tatattttac taacactaga atcccgacaa ttaagtcaaa aaaagttatc
       61 actcacctaa cctgaataaa aatggtataa tcgtaaggat cacactattt attaaggaaa
      121 cattatgaaa attgttcagg gagtacaact tcatctgatt aagaccaaac agtttaaaac
      181 caatcatatt acctttcgtt tttcaggtga tttgaaccaa aaaacagtag caaaaagagt
      241 cttagtggca cagatgttag caacagctaa tgagtgttat ccaactgtta ggcagtttag
      301 agaaaaatta gcacgacttt atggagctag cttgtcaact aacgtgttaa caaaagggtt
      361 agttcatatt gtggatatcg atattacttt tattcaagat agatatgctt gcaatgggga
      421 aaaaatacta gatgaaatga ttcagttttt aaaagatatc ttgttctcac ccctattatc
      481 catcgcccag tatcagccta aagtttttga gactgaaaaa aataatttga ttaactacat
      541 cgagtcagat agagaggatt ctttttacta cagctctctt aaggtaaaag aattgtttta
      601 ttgtaataag aatctacaaa tgtcagaata tggtagccca gaactaattg caaaagagac
      661 tgcctatact agctatcaag aatttcataa aatgctcaat gaagatcaga ttgatatttt
      721 cattttagga gattttgatg attatcgcgt tgttcagcta attcatcaat ttccacttga
      781 taaccgaaat aaaaacctaa atttctttca tttacaaaat tctgtcaata ttattaaaga
      841 atctattgaa aaaagagcag ttcatcaatc tattttacaa ttagcttatc acttcccttc
      901 agtttttgga caacgtgact attatgcttt agttctttta aatgggttgt taggctcttt
      961 tgcacattcc cgtctcttta taaaaattag agaagaagaa ggacttgctt atagtatagg
     1021 gtgtcgtttt gatagttata caggtttatt tgaaatttat actggaattg acagtcaaca
     1081 tcgcactaaa acgttacaac taatcatcca agaattaaat gccattaaaa tgggacgatt
     1141 ctcagaacaa ttgattaaaa agaccagatc gatgttgttg aataacgcct tattatcaga
     1201 agattataat aaaaatataa ttgaaagaat atacacatct tcttacattg attcttctta
     1261 ttctattaaa aattggatta aaggggttaa tgaagttaat aaagcagata tcattaaagt
     1321 agctaatctt ttaaagcttc aaactgtcta ttttttagaa ggaatataaa atgacaaaat
     1381 tagtaaagat aaactatcct aatattgacg aagaccttta ctatgtaaaa ttagaaaatg
     1441 gtttaactgt ttattttata aaaaaaatag ggtttttaga aaaaacagct atgttgacag
     1501 taggtttcgg ttctcttgac aataagttga cagtcgatga cgaatcacga gatgctccag
     1561 caggtattgc acacttttta gaacataaac tctttgaaga tgaatcaggt ggagatattt
     1621 cattaaagtt tacacagcta ggagcagaga caaatgcctt tacaactttc aaccaaacga
     1681 gtttcttctt ttcaacagct agtaaatttc aggaaaattt ggaactcctc caatattttg
     1741 ttctttctgc taatataaca gatgaatctg ttagtagaga aaaaaaaata atcgggcaag
     1801 aaattgatat gtatcaagat gatgctgact accgtgcata tagtggaatc cttcagaact
     1861 tatttccaaa aacaagttta gctaatgata ttgctggctc aaaagcatcc attcaaaaga
     1921 tcacgaaaat attattggaa acgcatcata cttattttta ccaacctact aatatgagtc
     1981 tattcattgt cggtgatatt gatattgacg aaactttttt agctattcaa aggtttcaaa
     2041 ccacattatc ctatccagat agaaaaaggg taactgttga tcctttacac tactatcctg
     2101 taattaaatc atcttctgtt gacatggatg ttactactgc caagctggtt gttggttttc
     2161 gagggtatct gaccttaact cagcattcac tattaacgta tcgtattgcc ttgaagctat
     2221 ttttatcaat gcttataggt tggacttcta aaatctatca tacgctatat gaagatggta
     2281 aaatagacga ttcatttgat gtggatgttg aaattcatca taattttcaa tttgtattaa
     2341 tatcacttga tacaccagag cctatcgcaa tgtctaacta tatccgtcaa aaattagcca
     2401 ctataaagat atcaaaagag tttacaaatg agcacttaaa tctattaaaa aaagaaatgt
     2461 atggtgactt tattcagagt ttagactcta tagaacattt aactcatcag ttcagtctat
     2521 acctgtctga ttctgataaa gaaacatatt ttgatattcc aaaaattata gaaagactca
     2581 ctctaaaaga tgttgttaca attggaaaag cattttttga aaaagctgat gcttcagact
     2641 tcacagtctt cccaaaatag atgaaaatct gttataatag ggttactata ttatttttga
     2701 ggtacctgta tgagtgaaaa aagtcttggt gaagtgttaa gagaatcgcg tgttggaaaa
     2761 aatatcacac tagatgatat agaattgaag acagggattt cttcccatta cttgctggca
     2821 atggaattgg atcagtttaa aattattccg gaagaaaaat ttgatcaatt tttaaaagaa
     2881 tatgctgaca ttgttgagtt agatttcaat actttaaaaa gacgataccg ttatcaagtt
     2941 aattccaaaa aagacagtga tataaaatct gtaactgaga ttgttgaaga gaagttaagt
     3001 aagaaacgat tacaagagaa gttgttatca catcagagca tggggtatgg tcaaccgtta
     3061 gaagtttcta aaaacaaaga aaccttagtt atccctgtaa agactgttgg tttagatagc
     3121 aaatcgccac taaaaacgat atcgcctgtt agccaattta aatcagataa caggttaatt
     3181 cctaaaaaaa atgtgtcacg tatgaggcga aatagcactg acagtcgttc taaaacgtca
     3241 ctatttccca tagttatatt aggaacgatt gcttttgcaa ttatcagtgt tatcatttta
     3301 ggtgtttggc aacaattcga aaagagtcaa agagctaaag aagctgaagt tgctttgctt
     3361 aaagcctctg agcagtctac taacggttta aaaaataatt caaatgatcg caaaactcaa
     3421 gtcacaactg aggggtcggg taattattta atagcgactg ttactaaatc taaagagacc
     3481 gttgatatca gtgtgtcttt aaccgaggca caaagtagtt ggatttctct aacaaattca
     3541 gaaattggtg aaggtggtat aacattgact caagactcgc caacttatac agcgacttta
     3601 cctgcagaaa taacagaatc attgttgaca cttggtgtga caaaaggtgt atctgtaaca
     3661 attgatggac aacctgttga tctatcacct ttaacaagta ctgacttaag ttatatcacg
     3721 tttaagatcc aataattaag gtagactaat gataaaaaaa gaaaatattc ctaatctatt
     3781 aactcttgtt cgaatcgcaa tgattccttt ctttcttttt attacttcct catctaataa
     3841 ggtggggtgg catatttttg cagctgtgat ttttgcaatt gccagtttta ccgattatct
     3901 agatgggtat cttgcgcgta agtggcatgt agccagtaat tttggaaagt ttgccgatcc
     3961 tctagcagat aagatgcttg tcatgagtgc ctttatcatg ttagttggac ttggcttagt
     4021 tcctgcgtgg gtgtcagctg ttattatttg ccgagaattg gcagtaactg gtcttcgatt
     4081 actacttgtt gaaaccggag gaaaggtcct tgcagctgct atgccgggaa aaatcaaaac
     4141 agcgacacaa atgttgtcta ttattttatt actttgccat tggatattcc taggaaacgt
     4201 cttactctat attgctcttt ttttcactat ttattctgga tatgattatt ttaaaggagc
     4261 aagctttctt tttaaggata cgtttaaata acatgtcagc tattattgaa cttaaaaaag
     4321 ttacatttaa ttaccataaa gaccaagaaa aaccaacatt agatggtgta tcgtttcatg
     4381 tgaaacaagg tgagtggctg tctatcattg gccataacgg atctggtaaa tcaacgacta
     4441 ttcggttaat tgatggatta ttggaaccag aatcagggtc tattattgtt gatggagatc
     4501 tactaaccat aactaatgtt tgggaaattc gtcataaaat tggtatggtc tttcaaaacc
     4561 ctgataatca gtttgttgga gcaactgttg aagatgatgt tgcttttggg cttgaaaata
     4621 aaggtattgc acatgaagat ataaaagaga gggttaatca tgctttagag ttagtcggca
     4681 tgcagaactt taaagaaaaa gaaccagccc gtttatctgg tggccaaaaa cagcgcgtag
     4741 ctattgcagg tgcagttgct atgaagccta aaattattat tttagatgaa gctactagta
     4801 tgcttgaccc taaaggacga ttagagttaa tcaaaactat aaaaaacatc cgtgacgact
     4861 accagctgac tgttatttcc attactcatg acttagatga agttgctctt agtgatagag
     4921 ttttagtgat gaaagatggt caagtggaat caacatcaac accagaacaa ttatttgcaa
     4981 gaggggatga actactccaa ttaggtcttg atatcccttt tacaacatct gttgtacaga
     5041 tgcttcaaga agaaggttat cctgttgact atggatatct cacagaaaag gaattagaaa
     5101 atcagttatg tcaattaatc tccaaaatgt aagttatact tatcaagcag ggactccttt
     5161 tgaagggcgt gcccttttta acattaattt agatatttta gatggttctt atacggcttt
     5221 tatcggacat actggatccg ggaaatcgac cattatgcaa ttgctaaatg gtttacacgt
     5281 tccgacaacg ggaattgtca gcgtagataa acaagatata acgaatcact ctaaaaataa
     5341 agagattaaa tctattcgaa aacatgtagg attagttttt caatttccag aaagtcaact
     5401 atttgaagag acagttttga aagatgttgc ttttggccct caaaattttg gggtctctcc
     5461 ggaggaagca gaagctttag cgcgtgaaaa actagctctt gttgggattt cagaaaatct
     5521 ttttgaaaag aatccatttg aactctcagg gggtcaaatg cgtcgtgttg ctattgcggg
     5581 tatccttgct atgcagccaa aggttttagt tttagatgaa ccgactgctg gtcttgatcc
     5641 taaagggcgt aaagaattaa tgactatttt taaaaagtta caccaatctg gcatgactat
     5701 tgttttagta acccatctga tggatgatgt ggccaattac gcagattttg tatatgttct
     5761 tgacaaaggt aaaattattt tatcaggaaa acccaaaaca atttttcaac aagtcagttt
     5821 gcttgagaaa aaacagttag gagttcctaa ggtgactaaa cttgctcaaa ggcttgttga
     5881 tagaggaata cctatctctt ctttgcctat taccttagag gagctaagag aggtactaaa
     5941 acatggataa gctgattctt ggtcgttata ttcccggaga ttctctcatt catcgtcttg
     6001 acccaagaag taaattatta gcgatgatta tttatattgt cattatcttt tgggctaaca
     6061 atgttgtgac aaatttgttg atgttgactt ttactttagc agttgttttt ttgtcaaaaa
     6121 tcaagttgtc tttcttttta aatggggtta aaccaatgat tggtattatc ctcttcacga
     6181 ctttatttca gatgtttttc tcacaaggag gaaaagtaat ttttagttgg tggttcatta
     6241 gcataactga tttaggattg agccaagcta ttttaatttt tatgcgtttc gttctaatta
     6301 ttttcttttc aacgctgtta acgttgacga caacaccttt aagcctatct gatgcagttg
     6361 aatcattatt aaaaccttta acaagattta aagttccagc tcacgagatc ggactaatgc
     6421 tttctttaag tttacgtttt gtgcctactt taatggatga taccacgcgt attatgaatg
     6481 cacaaagggc ccgtggagtt gattttggag agggaaattt aattcaaaaa gttaaatcca
     6541 ttattcctat tttaatccct cttttcgctt caagctttaa aagagccgac gcattagcta
     6601 ttgctatgga agctagaggt tatcagggag gagaagggcg aactaagtat cgtcaattag
     6661 actggcagct aaaagatagt ttagctattg gaatagtttc tttattgggt ttgctacttt
     6721 ttttcttgaa aacctctttg taatattttt tagcacaaaa cttttcttta ttagtaagaa
     6781 gtgaattgta cctcaaaagt tagatacaac atctaatgat tgaggtactt ttcttcattt
     6841 gaggaattga aaaccgctat ctcaactata ttaatcatcc caacaataac aaatcgaacg
     6901 aaatctaaaa ggactgagtc ctgttcaata cagaactaaa ttcttagttt aatgatatta
     6961 tcccgctttt taatgttgct aagaagaaga gttttatgat tttttacaac ttcttataat
     7021 atcaatgtag ttgtaatatt tttaatatat cttcaataac gaggtaataa ttaaaagata
     7081 ttatggataa cggagacaag tgaggtatta ttgaatgttt aagaaagaaa atttaaaaca
     7141 acgttatttt aattttggat tagtagcgtt agctctaaca atattagcca tcatttttgc
     7201 cttctcaagt aaaaatgctg atactaagtc ttatgctaag aagtcagaaa gtaaaatggt
     7261 aacaatcgac aaggttccaa aaaataatca tgctattact aaagaagaaa gcaaagaaaa
     7321 agcaaagagc attgcttcgg agcctattcc cacagtagaa aactctgtag ctccgacagt
     7381 aacagaggaa gcaccggttg ttcagcaaga agtgactcaa actgttcagc aggtatcttc
     7441 agtagcctat aatccaaaca atgtggtact ttccaatgga aatactgctg gtattgtagg
     7501 aagtcaagcg gcggcacaga tggcagcagc aacaggtgtt ccacaatcaa cttgggaaca
     7561 tataattgcg cgtgaatcta atggaaatcc taacgcaact aatgcttctg gggcatcagg
     7621 gttgttccag acaatgccag gttggggttc tacagcaacg gttgaagatc aagtcaatgc
     7681 agccttgaaa gcctatagtg cacaaggttt atcagcttgg ggttactaaa taaacatagc
     7741 tggaagaaat aaaacctatt gttagtattt actaacaata ggtttttggt atttaattgt
     7801 ctttatgatt tgtagtgatg aattagtctc aaaacaaaac attgccttat cagggaatat
     7861 agctcgtatt atttaggaaa actgaccagc acttaagtgc ctctgatatt taaggcagtt
     7921 atactgataa caagcaggaa aaaaactctt aaatgtttat aaggtcatta gcaattttca
     7981 gtattttaca ctactacact tttgagtttc aaccatttac taggagttgt ttctaagggg
     8041 aaacaacata gcttgatagc tatctattag ttattttagt gaatatatag cagaaaaata
     8101 aaacgctttc aaatatttct aagaattttt ctacctatct atttattcgc caaatatttc
     8161 tacgctgtaa cgtcgtccag ttggagtagc ggctaaacca ccttctgctg tttcacggaa
     8221 agcagttggc atggcagagc cgacttgata catagcatca ataacttcgt caacaggaat
     8281 ttgagattca atatcagcta aagccatatc agctgcgaca agggcgaaac ttgctcctag
     8341 ggcattgcgt ttgacacaag gcacttctac taggccggca acaggatcac agacaagtcc
     8401 taataaattt ttgataacaa acgcaatagc ttgactagct tgatgagatg ttccaccagc
     8461 tgctttaaca agagcagctg cactcatagc agctgcagaa ccaacttctg cttggcatcc
     8521 accttctgca ccagaaatag aggcgttatt tccaataaca agaccaaaag ctcctgcagt
     8581 aaataaaaac tctaattgtt ttttttctga taagtcaagt ttttcaatag ctgttgcgag
     8641 cactgctggt aagcatcctg cacttcctgc agtgggtgtt gcacagacaa gtcccatttt
     8701 agcatttaat tcgtttacag ctatagcatt tctaacagca ttaagaatag tagtatcaga
     8761 aaggctgttc ccttttttaa tgtagttatc cattttgacc gcatcgcccc ctgtcaaacc
     8821 actgatagat ttggttgagg ttagtccttc tgttacagct gctttcataa cttgtaaatt
     8881 gcgtgacatg attttgataa tatcttctcg atttcttcca gacatctcca cttccgtggc
     8941 aatcatgagt tcagcaatat ttccattaaa ttgttggtca gcttgtttga caagttcttc
     9001 aatagtataa aacatagctt tcctttctag tcaaagaagt tgacattata aatatgagga
     9061 atttttgcaa tttggttggc tgcttcttgg cactctctag aatcgacttc tataatcata
     9121 gtagcttttt caccagcaga ttcacgtgta acattcattg tggcgatatt aatattattg
     9181 gaagatagga tatcagttac ctttgcgatc attccgggaa tatctttgtg tacagtaact
     9241 atagtaggag tattcatgga taacgagaca gaaaaaccat ttagttctgt tacttgaatg
     9301 tttcctcctc caattgaaac accagtaaca ctaagtgttt tgtcagcttt tttgacactg
     9361 attttaacag tattgggatg gggagcatta ctatctttta agatatccca atagattttt
     9421 atcccttttt gatgagcaat ttctagagaa tttttaatat caggattatc agtatccata
     9481 cccataattc ctgcaacaag agccttatca gtaccatgtc ctctgtaggt tttagcaaat
     9541 gaattataaa ggtgaaacgt cacttcatca ggaatatctc caaagatgga atggactacc
     9601 ttaccaattc tgacggcacc agctgtgtga ctacttgatg gaccaatcat tactggccca
     9661 atgatgtcaa aaactgattg aaatttttgt gtattcatag gcaactccgt tttttatttc
     9721 tatgtttatt ataacaaaaa aatatcaaaa aacagcaata taattataaa aaattatttt
     9781 tataataaaa aattattgag caataaaatg attggcattc cacgcagtaa ttgttataat
     9841 aaggtttacg ctgatggcgc ttcaaaatcg accttcaaat cgacttttga aaacgacgac
     9901 cttcaatcgt acgttaactg ataagaaaaa gaatcataat attcataata tgatgattat
     9961 ctttttctat cttattattg atgggagaat tttttatgac agataactca aagatacgtg
    10021 ttgtcgttgg tatgagtggt ggcgttgatt catctgtaac agctctactt ttaaaggagc
    10081 aaggttatga tgttattggt gtcttcatga aaaactggga cgatacagat gaatttggtg
    10141 tttgcacagc tactgaagat tacaaagatg tagcagccgt tgctgatcaa atcggtattc
    10201 cttactattc agtcaatttt gaaaaagaat attgggacag agtatttgaa tatttcttgg
    10261 ccgaataccg agcaggtcgt actccaaatc ccgatgtcat gtgtaataag gaaataaaat
    10321 ttaaagcttt ccttgactat gccatgactt taggtgcaga ttatgtagca acgggacact
    10381 atgctcaagt caagcgtgat gaaaatggta cggttcacat gttacgtgga gctgataatg
    10441 gcaaagacca aacctacttt ttaagtcaac tatcacagga acaactacaa aagactttat
    10501 tcccccttgg tcatttgcaa aagtcagaag ttagagaaat cgctgagcga gcagggcttg
    10561 caacggctaa aaagaaagat tcaacaggta tttgttttat tggtgaaaag aatttcaaac
    10621 agtttttgag ccagtactta ccggcacaaa aaggtcgcat gatgactatt gatggtcgcg
    10681 atatgggaga acatgccggc cttatgtatt atactattgg tcagcgtggg ggtctgggca
    10741 ttggtggtca gcatggtggg gataatcaac cttggtttgt tgtcggtaaa gatttgtcgc
    10801 aaaatatttt atacgttggt caaggtttct accatgaagc cctaatgtca aatagtcttg
    10861 acgcctcagt catccatttt acacgtgaga tgccagaaga gttcacattt gaatgtactg
    10921 ctaaatttcg ctatcgtcaa cccgattcac acgtgacggt gcatgttcga ggagataagg
    10981 cagaagttgt ttttgcagag ccacagcgcg cgattactcc tggtcaagct gttgttttct
    11041 atgacggaaa agaatgcctt ggtggtggta tgattgacat ggcttataaa aatgggcagc
    11101 cttgtcagta catttaatga atcttttatt aagataaaaa gaaagggaca ttcaacaatt
    11161 cctttgacat catatgatat tatttataaa aac
//
LOCUS       DAUCXI010000049        11149 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.049, whole genome shotgun sequence.
ACCESSION   DAUCXI010000049 DAUCXI010000000
VERSION     DAUCXI010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11149
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.049"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..785)
                     /locus_tag="VGY43_001507"
     CDS             complement(<1..785)
                     /locus_tag="VGY43_001507"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEQ4302677.1"
                     /translation="MEKIEFIQYRKLKNITIDFDKNINIIAGTNGTCKSSILHLISNS
                     HQRVSNSSRNPILSTIQKMNKIFNPKIESLARGDKKYNDPAPGMTGTLYTAFYENYSL
                     DFRRHNSRTVNNTERFAIKPKYKRGTSDRLPEIPIIYLGMFRLFSYGEWEGESKFHNI
                     INKLPKQYLDQLSMLYKKFTGYEIKFDGKLNNLGGIRSKTEFSTNTEGIDSNTISAGE
                     DNLLTILISLVSLKAYYESITPDTEKTVESILLIDELDASLHP"
     gene            complement(787..1170)
                     /locus_tag="VGY43_001508"
     CDS             complement(787..1170)
                     /locus_tag="VGY43_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEQ4302678.1"
                     /translation="MVKINEMLSKYNIKLFEFPDTMWKRSGFYYPDLRIIYVNQNLSQ
                     IEKEKVILHELGHIEHDPKQYQRLLLKYENQADRFMIRELIKNYLSSHNVVDFNWLQF
                     ATTYQISTTWGQQMIQEEFQNIVGV"
     gene            complement(1154..1495)
                     /locus_tag="VGY43_001509"
     CDS             complement(1154..1495)
                     /locus_tag="VGY43_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4302679.1"
                     /translation="MDEKDLKRIIESRYNSVRAFAIENDIPYTTMRSILERGVMNAKA
                     ETIFKICDILGINPESFAEEKTDWQATIDLSNLREKVVMFDGKPLSDKDVEKIEAIIK
                     ISLGVGNGEDK"
     gene            1693..1905
                     /locus_tag="VGY43_001510"
     CDS             1693..1905
                     /locus_tag="VGY43_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEQ4302680.1"
                     /translation="MKNIEHIRKEKGVSLVDIADCLRLKSQTVREKINGDSDFKFGEA
                     LKVQQTFFPEFDIVYLFKERKESSVG"
     gene            1933..2652
                     /locus_tag="VGY43_001511"
     CDS             1933..2652
                     /locus_tag="VGY43_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEQ4302681.1"
                     /translation="MNHLINVTLNENQEPVVSARDLHKELKVKTRFSEWVKQNFKILE
                     EGYDFTSVVGTTVVNNGAVREIQDYVLSLDAAKNLAMVSKTDKGKEVRKYFIQVEKDF
                     NSPEKIMARALLMADKKVHKLEAQIEADRPKVLFADAVEASETSILIGDFAKILRQNG
                     YNIGQNRLFAWLRENGFLIRKNGESYNMPTQRSMDMKLFEVKERTHQEPNGSIRISKT
                     TKMTGKGQQYFINKFLNEKVG"
     gene            2656..2823
                     /locus_tag="VGY43_001512"
                     /pseudo
     CDS             2656..2823
                     /locus_tag="VGY43_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054766.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3069..3380
                     /locus_tag="VGY43_001513"
     CDS             3069..3380
                     /locus_tag="VGY43_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEQ4302682.1"
                     /translation="MPKAELVYRPAKQSEKAEAGDYEHLCQIWEGLTVGTAKVWATEM
                     RDHPDFKQFVLNPTHKIVFIDYEGFRLFVKWKSRNRYKPKKETLVEMLENIKFEKRVG
                     V"
     gene            3382..3552
                     /locus_tag="VGY43_001514"
     CDS             3382..3552
                     /locus_tag="VGY43_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302683.1"
                     /translation="MNKLELFLLVTTVALAIVARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            3545..3748
                     /locus_tag="VGY43_001515"
     CDS             3545..3748
                     /locus_tag="VGY43_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302684.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            3745..4130
                     /locus_tag="VGY43_001516"
                     /pseudo
     CDS             3745..4130
                     /locus_tag="VGY43_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4275..4478
                     /locus_tag="VGY43_001517"
     CDS             4275..4478
                     /locus_tag="VGY43_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302685.1"
                     /translation="MNYLEYALAYLERELEIIDNDVIEVELPNGGWEFVPNPYYEEGL
                     HDSPYYRSQVAKDILDIKGLLGR"
     gene            4567..4866
                     /locus_tag="VGY43_001518"
     CDS             4567..4866
                     /locus_tag="VGY43_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302686.1"
                     /translation="MIEVTFKAESMAGVFDAMREALGMPKTVTKDVVEEEPAPKKKEE
                     SVTLALADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEENQFAEFVEKLEAL"
     gene            4866..6023
                     /locus_tag="VGY43_001519"
     CDS             4866..6023
                     /locus_tag="VGY43_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEQ4302687.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGTLEKLIGKTTFADLLAEVIDKPQGKPVLVKNSDKRPALNSLEQAIKDFE"
     gene            6032..6595
                     /locus_tag="VGY43_001520"
     CDS             6032..6595
                     /locus_tag="VGY43_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEQ4302688.1"
                     /translation="MIMTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            6638..8560
                     /locus_tag="VGY43_001521"
     CDS             6638..8560
                     /locus_tag="VGY43_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEQ4302689.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPCQWQCTMVLA
                     QELGLPSSLEKCALYLKLAQEKDNSGKNLIRYFSLPCKPSKANGGRTRNLPEHAPEKW
                     QMFIDYCIQDVVVEMAIAEKLESVPVHDREWGYYACDQRINDRGVALDKELVASALYC
                     KDVKMKSLSGELKAITGLDNPNSRAQLLPWLKEHGYSVNGLTKADVEQELKTAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDCCTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKL
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIVYEGQGDKAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGYGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAGG
                     LPLNSEGYVTKYYMKD"
     gene            8565..10949
                     /locus_tag="VGY43_001522"
     CDS             8565..10949
                     /locus_tag="VGY43_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEQ4302690.1"
                     /translation="MKQEKLIVKSSPLQELHIATGNSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWRDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTEGS
                     TANGLVIYDEVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDTTPTNKLPSSK
                     AMNAFVSDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPELHARSSHPVVYDPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYAIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLARNSFTQRMNELNFENKNAKMEGKTVRCWIGFRLKGEF"
BASE COUNT         3640 a         1957 c         2476 g         3076 t
ORIGIN      
        1 tcaggatgca aagaggcatc taattcatca atgagtagaa tactttctac tgttttctcg
       61 gtatcgggag taatactttc ataataagct tttagtgata caagtgaaat caatatggtt
      121 aaaaggttgt cttctccagc agatattgta tttgagtcaa taccttcggt gtttgttgaa
      181 aactctgttt tagatctgat gcctcccaaa ttgtttaatt taccatcaaa tttaatttcg
      241 tatccggtga attttttgta aagcatactt agctgatcaa gatactgttt tggtaattta
      301 ttgataatat tgtgaaactt actttcaccc tcccattctc cgtacgagaa tagccggaac
      361 atccctaggt atattattgg aatttccggg agtctatcag aagttcctct tttatatttt
      421 ggtttaatag caaaacgctc agtattatta acagttctac tattgtgtct cctaaaatct
      481 agtgaataat tttcgtaaaa tgctgtgtaa agtgttccag tcataccagg agcaggatca
      541 ttgtattttt tatctcctct ggccaacgat tcgattttag gattaaatat tttgttcatt
      601 ttctgaattg ttgataggat tggatttctt gaagaattcg agactctttg atgggaatta
      661 ctaattaaat gcagaatgga tgatttacaa gttccattag taccggctat tatattaata
      721 ttcttatcaa aatcaatcgt aatgttttta agttttctat actgtataaa ttctattttt
      781 tccatcttac actcccacga tattctgaaa ctcttcctgt atcatttgtt gcccccaggt
      841 agtcgagatt tgatatgtcg tagcaaactg taaccaatta aaatcaacga cattgtggga
      901 tgacaagtaa tttttgatca attccctaat cataaatcta tcggcttgat tttcatattt
      961 tagtagcaat ctttgatatt gcttaggatc gtgttcgata tggcccagct catgtaaaat
     1021 aactttttct ttttctattt gtgatagatt ttgattgaca taaattatcc taaggtcagg
     1081 atagtaaaac cctgaccttt tccacattgt gtcgggaaac tcgaataact ttatgttgta
     1141 cttactaagc atctcattta tcttcaccat tccctactcc taaagatatt ttaataatag
     1201 cttcaatttt ctctacgtct ttgtcagaca aaggtttgcc gtcgaacatc acaacctttt
     1261 cgcgtagatt ggataggtca atagtggcct gccaatcagt tttttcttca gcaaaacttt
     1321 ctgggttaat tccaagaata tcacatattt taaaaatagt ttctgctttt gcattcatca
     1381 caccgcgctc taaaatggag cgcattgttg tgtatgggat atcattttca atagcaaaag
     1441 ccctaacgct attatatcta ctttcgataa tcctctttaa atctttttca tccatttttt
     1501 taatttcctt ttttcttttt ctactatata ataacatacg aaaaatcata tttcaagaca
     1561 aaaaaataac aaaaaattta aaaaaactgt tgactgtata cgaaaaatca tatataatta
     1621 aatcaagctt aaggaaacga cagcttttta aaataaaata atatacgaaa aatcgtattg
     1681 gaaaggaatg atatgaaaaa catcgaacac attcgaaaag aaaaaggtgt ttcattggtt
     1741 gatattgccg actgtttacg gttgaaatct caaacagttc gagaaaaaat taacggtgac
     1801 tctgatttta aatttggtga agcattgaaa gttcaacaaa ctttttttcc agaatttgat
     1861 atcgtctatc tttttaaaga gcgtaaagaa tcatctgtag gatgatatac gaaaattcgt
     1921 agaaaggaaa ttatgaatca tctaattaac gtaacactaa acgaaaatca agaaccagta
     1981 gtaagtgcaa gagacttaca taaagaatta aaagtcaaaa ctcgttttag tgagtgggta
     2041 aaacaaaact ttaaaattct tgaagaagga tatgatttta caagtgtagt tggaactacg
     2101 gttgtaaata atggggctgt cagagaaatc caagactacg ttctctcact tgatgctgcc
     2161 aaaaatttgg caatggtatc caagactgac aaaggcaaag aagtccgtaa atacttcatc
     2221 caggttgaaa aagacttcaa cagtcctgag aaaatcatgg caagggcgtt gctgatggct
     2281 gataagaaag tgcacaagct ggaagcacaa atcgaggcag accgtccaaa ggtgctattt
     2341 gctgatgcgg ttgaggctag tgagacatct atcttgattg gtgattttgc taaaatctta
     2401 cgtcagaatg gttataacat cggtcaaaat cgcttattcg cttggttgcg tgagaatggc
     2461 ttcctgattc gtaaaaatgg cgagagctac aacatgccga cacaacgaag catggacatg
     2521 aagctgttcg aagtcaagga acggacgcac caggagccaa atggcagtat ccgtatcagc
     2581 aaaactacca agatgacagg taaaggccag cagtatttta ttaataaatt tttaaatgag
     2641 aaagtggggt agagcatgag accaaaacga tacccatata gcgggaagaa aaacagaaaa
     2701 gcaaaagaca tcagcttgag actgatgtct aaagaggaat tatctgattt tagtcgtcag
     2761 attgctgaag ccactcgtga taatgtcgaa ccatttcgag agccgcaaag tatgatgagc
     2821 taagtattaa ctttgcaagg tttacagatt ccccttcgct ttctttcgca tatctattgt
     2881 aatggtactc aataacttcc agaatttctt cggttttacc attgcttaga gattgggcga
     2941 aattgttgaa atctttattc atataatcac cttttttcga gatgattata tcaaaaaagt
     3001 ccgacgggaa tcggactcaa aacaaaaaaa tatttactta attataacac aagagagagg
     3061 atattaatat gccaaaagct gaattagttt acagaccagc taagcaatct gaaaaagcag
     3121 aagctggtga ctatgaacac ctttgccaaa tctgggaagg tttgacagtc ggaacggcta
     3181 aggtttgggc gacagaaatg cgtgatcatc cagactttaa acagtttgta ttaaatccaa
     3241 cgcataaaat cgtattcatt gattacgaag gtttccgttt atttgttaaa tggaaaagtc
     3301 gtaaccgcta taaacccaag aaggaaaccc tggtagaaat gcttgaaaat attaaattcg
     3361 aaaaaagagt aggagtataa catgaacaaa ttagaattat ttttattagt aacaactgtt
     3421 gctttagcaa ttgttgccag gatacaatat gaagtcatca aaaaacacaa ctcgccagag
     3481 aataagcgaa aaatttttag ggaagtagct ttagaaaaca gcaagaaatg gagtgcagaa
     3541 cgttatgtct aaatgggaat tacaaaaaca actactggaa aatgcgacag attttgagag
     3601 cacagttgag gctttacttg acttaaacga gtctggcgaa atatctgatc tggaactctt
     3661 actgaactta aaggataaat tcagaagcta ttccaaagaa aaaatacgta tccttaatga
     3721 aattctcaag ctaggaggtg cagaatgatg acaacttttg aaaagattat taagaaaatt
     3781 aatcggattg agggggagtt agttaaacct gaagctgaaa gacgagatag cttactatcc
     3841 tatctgctca gttgggttct attaaacaag atttaaaatt gatgctttgg attgagctac
     3901 cgacgttaaa tgacgtagag agatatgaag ctctttatca aggaaatgat tttaaattca
     3961 gtgaaacttt cttagagcgt caagcgacga gaaaagcctt ttggagacga ttagctaaag
     4021 aaactttcaa agaagaccag gataagagga actttgttaa gttggctgag aaagaattta
     4081 aaggtgcaac tttgtcatgg caagaatttt tgtggggtaa aaagaaatga atatatcact
     4141 aaaatttatt gatgaaaccc tagctggctt aaatgatatt ttacgtcagg ggggggctct
     4201 tgctcccaaa accaagccct ggcggacgca gtttttatac taacagtttt aaaacaggta
     4261 attgaggaga gaaaatgaac tatttagaat atgcactagc ttatcttgaa cgtgagttag
     4321 aaattattga caacgatgtt atcgaagttg agttgcctaa cggaggttgg gagtttgtgc
     4381 ctaatcccta ttacgaggaa ggtttacacg atagcccata ctatcgcagc caggttgcta
     4441 aagacattct tgatattaaa ggacttttgg ggaggtgagg ctattgattg catcaaaaaa
     4501 agacggctta ggaaaccgtc aacaattata cacaattaaa ttataacaca gaaagagaga
     4561 aacacaatga ttgaagtaac ttttaaagca gagagcatgg caggtgtttt cgatgctatg
     4621 cgtgaagctc tgggtatgcc gaagacagta accaaggatg ttgttgaaga agaaccagct
     4681 cctaaaaaga aagaagagtc tgtaactttg gcattagctg atattaagaa aatggctaaa
     4741 gccaaggttg aagaagggaa gtcaaaggac atcaaggaag tcttgaaaga gatgaacgtc
     4801 gcaaaagttg gtgaacttga agaaaaccag tttgctgagt ttgttgagaa gttggaggcc
     4861 ctctaatgcc agtagaaaat cacgcactac tgtctgcttc tagtgctcac agatggcttt
     4921 attgccctat gctgccgaga ttagaagcag actatcctag ccgcgatacc gtatacactc
     4981 aagagggcac aagcgcccat gagctttctg aaatcaaact gatgtacaag tctggtaaaa
     5041 tcaccaagcg taaatttaac acgttaacca aggcttttaa ggaaaactca gacttctaca
     5101 acgaagagat ggaagagatg acggaacttt acacagatat tgttatggag cacctaaatg
     5161 cttatgagaa cgccgaaatt gaacttgaaa aacgggttga ttttagcgac tgggtgcctg
     5221 gcggttttgg gacttcggat gttgtcattt tagcggatgg ggtcattgaa attattgatc
     5281 ttaagtatgg caagggcatg cctgtgtctg ctaaccaaaa cccacagatg gggctgtacg
     5341 ctctaggagc ttatgcttcc tacgatatgg tttatgactt tgaccgtatc aaaatgacca
     5401 ttattcagcc acgtttagat tcggttagtt ctgttgacat ttacgtggag gagttactct
     5461 actgggcgga taatgttgtc ttgcctatgg ccgctcaagc agacgcaggc attggtgact
     5521 ggaacctaag tgaaaaagta ttgcagtggt ctcctgtcgc agctaaattg gtaccaagag
     5581 cgcaagaaaa ttgggaatta attgataaat atgactatca ggagcctgtc tatttatctg
     5641 atgaagccgt cgcagagatt cttgacaaag cctcagctat caagaagtgg gttgagtcag
     5701 ttgaagccta tgccctgaaa gaagcactct cgggaaaaga agttccaggc tataagattg
     5761 ttgaaggtag aagtaatcga gtcatcactg ataaagacaa agcaattgat attttacaag
     5821 ataacggctt tgacgatgag atttttaaac cgaaagagct gttagcaatg ggaactcttg
     5881 aaaagttaat aggtaaaacc acttttgctg atttattagc agaagtaatt gataaaccac
     5941 agggcaaacc tgtccttgtt aaaaatagcg acaagcgacc cgcattaaat agcttagaac
     6001 aagcaattaa agattttgaa taggagaaat tataattatg acaccaaaca caactaaagt
     6061 agtaaccgga aaagtacgcc taagctatgt agctttacta gagcctaaag cctttgaagg
     6121 tcaagaggct aagtattcaa cagttatctt aattccaaaa acagacaaag tcacaatcaa
     6181 gaaaattaaa gacgcgcaga aagctgctta tgaggctgcc aaggacaata aactcaaagg
     6241 ggttaaatgg gagcgcgtta agacaacgct tcgtgacggc gacgaagaaa tggataccga
     6301 agagcaccca gagtacgctg gacacgtgtt catgtcagtg tcaagtaaaa ctaagccaca
     6361 aatcattgac aagtataaaa accccgttga ctcagcggat gaagtttact ctggcgtcta
     6421 tgctcgcgta tcacttaatg cctatgctta caacacagcg ggaaataaag gaatctcttg
     6481 cggattaaac aacgtccaaa ttgttgctaa aggagactac cttggcggcc gttcgtcagc
     6541 tgatgcagat tttgacgagt ggaacgaaga agaggacgaa gacgacattt tatagtagag
     6601 ggcctcttta gaggctcctc atttttaaag gagaggtatg agacatttaa atattgatat
     6661 tgaaacctat agttcgaatg acatcaaaaa tggggtttac aagtacgctg acgcagaaga
     6721 ttttgagatt ttacttttcg cttactctat agatggcgga gaagtagagt gtcttgattt
     6781 gacaaggcag tctctacctg aagacatcaa agatatgtta tttgatgata aagtccgaaa
     6841 gcacgccttt aatgcccaat tcgaaagagt ttgtctcagt cgttacctcg gtctacctta
     6901 ctatctagat ccttgccaat ggcaatgcac tatggtgctg gcccaagagt tgggtctgcc
     6961 ttcaagcttg gaaaagtgtg cgctgtattt aaaattagcg caggaaaaag ataactcggg
     7021 taaaaactta atcagatact tttccctgcc ttgcaaacca agtaaagcta acggtgggag
     7081 aactagaaat ttaccagaac acgcccccga aaagtggcaa atgtttattg actactgcat
     7141 ccaagacgtt gttgttgaga tggcaattgc cgaaaaacta gagtcagttc ctgtgcacga
     7201 ccgtgaatgg ggctactacg catgcgacca gagaatcaac gacagaggtg tggcgcttga
     7261 taaagagtta gttgcttcgg ccttgtattg taaagatgtt aagatgaaaa gtttgtctgg
     7321 tgagctaaag gccataacag ggcttgataa tcctaatagc agggcgcagt tgctaccgtg
     7381 gctaaaagaa catggctatt cggttaatgg tctgactaaa gcggatgttg agcaggagct
     7441 taagacggcc gaaggagaac ttaagagagt tttagaactt aaactacaaa ccgctatgtc
     7501 aagtctaaaa aaatatgaag ctatggaaag agctatgtgc tcagacggac gagttcatgg
     7561 actacttcag ttttacggag ctagcaggac aggaagatgg gcgggcagag ttgtccaagt
     7621 acagaactta gctaggaatt atataaagga cctagatgat gccagagagt acgttaaaaa
     7681 gcgtgatatt gatgctgtgg agattttata cgatagtctt aacgacactt taaagcagct
     7741 cgtacgaacg gcactcgtgg ccaaagactg ctgtaccttc tatgtctctg acttctcagc
     7801 gattgaggct agggtgattg cgtggtttgc tggagagcag tggaggcttg acgtgttttc
     7861 gacgcacgga aaaatctatg aggcatccgc tagccagatg ttcggaattc caattgagga
     7921 gattgataag gaactacgcc aaaaaggcaa aatctcagag ttggcacttg gctatcaagg
     7981 aggtcctgga gcgctcaagc agatgggagc tctaaatatg ggagtcaagg aagaggagct
     8041 ccaagggcta gttgatgact ggcgcagggc caataagaaa atcgtccaat tttggaaaga
     8101 tgtgcagaga gccgccatca aagctatcaa atcgagagca ccaataaaac ttggaaaact
     8161 acgatttaga taccgtaaag gtttcctctt tataacattg cctagcggta ggaacttagc
     8221 ttatgcaaga gccaaggttg agccaggcga ctatggagac aaaatcgtct atgagggcca
     8281 aggagataag gcctacttca cagcgcaaga gacttacggc ggtaagcttg tcgaaaatat
     8341 cgttcaggcg acggccaggg atattctagc tgaagcgctt ctgaggattg aagctgcagg
     8401 ctatggtgtt gttttccacg ttcatgatga ggctattatc gaaggctcag gcctgacaat
     8461 cgaagaagtt aatgatttga tggctcaggc tcctgaatgg gcggggggtc ttcctttaaa
     8521 tagcgaaggc tacgtaacaa agtattatat gaaggattag atagatgaag caagaaaaac
     8581 taatagtaaa gtcttctcct ttgcaagagc ttcatatcgc aacgggtaat tcacgaacag
     8641 ctaagacgtg gaaaaatatt acgctaactt ggcaggagct ggttgagagg ttagagaaac
     8701 ctacagtcac ccaagagacg tttgcggagt accagaagat gtctcgagca gaaaaagggc
     8761 aagcaaaaga cgtaggaggt tttgtcggcg ggtggctaaa gcagggtaaa cggaaaaacg
     8821 aaaatgttca aagtaggtcc ttggttgcgc ttgacgcaga tagcccaagt aaagatttct
     8881 tagataggct agacctgctt gcagactacg catacgtact ctacagtact cacagccact
     8941 caaaaaaagc tgctaagtac cgtcttatta tccctactga ccgtttaatg atgcctgatg
     9001 aatatgagcc agtcgctagg tacttggcta atcaactagg catgtcgaac tttgatgaca
     9061 cgacttatca aagtgtgcgt ttgatgttct ggccgagcca ctcgagagat gctgacttta
     9121 cgtttaaata taacgatgag gcttttctaa gtgttgatga ggtgcttgat acatacccgg
     9181 actggcgtga ctcaagcttc tggccagaaa gcccgacgca cgctgttaaa agacagcgtg
     9241 aagctaaaaa acaaggtgac ccacttagta aaaaagggct tattggagcc ttttgtcgta
     9301 actatgacat tagacaggcc attgcaacgt tcttgcccga ggtttatgaa gaaggaacga
     9361 ctcctgatag gtacacctac actgagggtt caaccgcaaa tggcttagtc atctatgatg
     9421 aagtcttcgc ttatagccat cacgggacag atcccgtggg ggatacgctt gtaaatgcat
     9481 acgaccttgt tcgtatccat aaattcggag agcaagatag cgaggctaaa gatactactc
     9541 ctactaataa gttgccatca agtaaagcga tgaatgcttt tgtctctgac ttacccgaaa
     9601 ttaaagacta tttaatggcg gaggctttag gcgatttcga tgaagagtta ccagtcgaag
     9661 atgacagaag ctggcttgaa attgatgaga ggggcgaacc tgaggtcaat agttatttgc
     9721 tagcaacgca gattattaag gaggttccga tttattggga cggcttagaa tttttacgct
     9781 acgacgctaa aaaaggcatc tggttgccaa acgcagagga gtatttgaag agttatatct
     9841 caactaagaa actcggtaaa attactaaga ttaggcacat tagcgaaacc gtcgtagcga
     9901 ttaaggcaca ggctttctca agcgaagtgt ttactgagag cgatcttaac aagatagtgc
     9961 tagcgaacgg agtctatgac ttgagggata acagttttaa gactaagttt gatccagaat
    10021 tgcatgcaag gtcaagccat cccgttgtct atgaccccga ggcggcctgt gaaacctttg
    10081 agggttttct tagggagacc gtcggagctg aaaatataga tttcatcttt gagtggttcg
    10141 gctataactt ttatcgcgaa tatgctattc aaaaaatgct attcatctac ggcagcggcg
    10201 gtactggtaa atcaacactg attaatattt tacgtgaaat gataggtgct gataattact
    10261 cagccgtgac actgcagtac ctgatgcaag aacgctttgc aaaaatcggc ttatatcgaa
    10321 agactgctaa cttcgatacc gatgctaaac ctcaatactt agcagatggc gcaacactta
    10381 aaatgttgac gggggaggat actattcacg cagaccgtaa aaataaagag ccgattaact
    10441 tttacaatta tgctaagctg tcttttgcca tgaatgagct cccacctatg cgagatttca
    10501 gtgggggact taagcgccgc atgatgatcc tcgagatgga taaggtttta acgcaggaag
    10561 ttaaggcgaa atacccgcta gataagatta tgagcgaggt gccaggtatc tttaataggg
    10621 cgatggaggg gcttagaaag gccttaagta agagagattt cagtattagt gccagcatga
    10681 ggtcaagtgt cgagaaatgg gaaaaaggta acgatgtcgt ggccatgttc cttgaagacg
    10741 agtgtgaact tggtgaagac ttcaaagttc ctgttaggga tgtctaccca gcctacaagt
    10801 tctattgtca ggattcaggc tacaaacctt tggctaggaa ttcgtttacg caaaggatga
    10861 atgaactgaa ttttgaaaat aagaacgcaa aaatggaagg caagaccgta agatgttgga
    10921 ttggttttag gctaaaagga gaattttaaa gggttacgtt tttcaacaaa aaaggtaaac
    10981 aggagatata aggttacgta gttacgcaga attcagactg ataaaaaatt ttataagttg
    11041 aaaaaaaacg taactacata actttcctga aaaacctttc ctgtttaagt caatttacat
    11101 aactaacgca acttttatgc aacctcaaaa aacctttcat agcaatagt
//
LOCUS       DAUCXI010000050        11013 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.050, whole genome shotgun sequence.
ACCESSION   DAUCXI010000050 DAUCXI010000000
VERSION     DAUCXI010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11013
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.050"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            27..731
                     /locus_tag="VGY43_001523"
     CDS             27..731
                     /locus_tag="VGY43_001523"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEQ4302691.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVIAGSFSK
                     RFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            855..4580
                     /locus_tag="VGY43_001524"
     CDS             855..4580
                     /locus_tag="VGY43_001524"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEQ4302692.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIEALPGQFDQRAASSQE
                     ALLLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFETYQADDFATYKAEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDDVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRDGEVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNGEIIVDLERRFLDTNGVRVVVDVKVVDKDLTV
                     PEARTTSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKVLSPEFKAAGENIYYIPGQAISEDIDFDLIKDNFSQFEAIQAQHKIT
                     AASAAKYGGVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGAGLLAAFEGKLEEVYPTEFEQADALEEVPAVVSDAVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGSSVNLVPFVTLNEAAITESVDTMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIENGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK"
     gene            4741..6195
                     /locus_tag="VGY43_001525"
     CDS             4741..6195
                     /locus_tag="VGY43_001525"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEQ4302693.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNPNFIGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDSGIQCNRYTDETQLAICSMEYIYFARPDSTIHGVNVHTARKNMGK
                     HLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHAADEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            6223..7245
                     /locus_tag="VGY43_001526"
     CDS             6223..7245
                     /locus_tag="VGY43_001526"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEQ4302694.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVREPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNNPVKFEEVVSGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQLIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVRAALPLIKEELVNGIGHITGGGFIENVPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     DSVVIK"
     gene            7413..7967
                     /gene="purN"
                     /locus_tag="VGY43_001527"
     CDS             7413..7967
                     /gene="purN"
                     /locus_tag="VGY43_001527"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEQ4302695.1"
                     /translation="MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKAAYEQAIVDLLDKHEIDLVCLTGYMKIVGETLLLAYEGRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            8151..9698
                     /gene="purH"
                     /locus_tag="VGY43_001528"
     CDS             8151..9698
                     /gene="purH"
                     /locus_tag="VGY43_001528"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEQ4302696.1"
                     /translation="MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDDAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YPFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVADPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDVDAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(9757..10881)
                     /locus_tag="VGY43_001529"
     CDS             complement(9757..10881)
                     /locus_tag="VGY43_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEQ4302697.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNENTKPSIKVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFTVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
BASE COUNT         3181 a         2134 c         2535 g         3163 t
ORIGIN      
        1 aaacagaaag aaaggcgaat aatcaagtga ctaaccagct tatttataaa ggaaaagcga
       61 aagatattta tagtacaaaa gatgaaaatg tgattagaac ggtctataaa gaccaagcta
      121 ctatgttgaa tggagctcgt aaggagacta ttgatggcaa gggagcacta aataatcaga
      181 tttcatctct tatttttgag aaattaaata aggctggtgt ggtgacacat tatattgagc
      241 aaatttcaaa aaacgaacaa ttgaataaaa aagttgatat tattccactt gaggtggtgt
      301 tacggaatgt gatagcaggc tcattttcaa aacgttttgg agtggaagaa ggacgtgttc
      361 ttgaaacgcc aattgtggaa ttttactaca aaaatgatga tctgaatgat ccttttatca
      421 atgatgagca tgtgaagttt ttgggtattg ttaatgatga ggagattgct tatctgaaag
      481 gagagactcg ccgtattaat gaactcttga aaggttggtt tgctcagatt gggcttaact
      541 tgattgactt caagttggag ttcggatttg atcaagaagg tacaattatc ttagcagatg
      601 aattttcgcc tgataactgt cgcctatggg ataagaatgg taaccatatg gacaaggatg
      661 tttttagaag agaccttggc aacctgacgg atgtctatca agttgtactt gagaagttga
      721 tagcattgta actagaagag gaaggaattg aatccgttcg ggaaactccg aaaaaaagat
      781 ggaacttact gaaatctcaa tttcagatgt cctcctattt tccagtcgct cccttgtcgg
      841 acttggtatc ttatatgaat aaacgtattt ttgttgagaa aaaggctgac tttggtatta
      901 aatcggctag tcttgtgaaa gagttgacgc ataatctaca actgacctct ttgaaggctt
      961 tgcgtattgt gcaggtctat gatgtcttca atttggctga ggatttgctg gcgcgtgctg
     1021 agaagcatat tttctctgag caggtgacag actgtctttt gacggaaact gaaatcactg
     1081 cggagcttga taaggttgcc ttctttgcca ttgaggcgct tcctggtcaa tttgaccaac
     1141 gtgctgctag ttcgcaagaa gctttgctat tatttggaag tgacagtcag gttaaggtca
     1201 atacagccca gctttacttg gtcaataagg atattacaga agcagagctt gaagccgtta
     1261 agaactatct tttgaaccct gttgattcgc gtttcaagga cattactttg ccgcttgaag
     1321 agcaggcttt ctctgtgtct gataagacga tccctaatct tgatttcttt gaaacttatc
     1381 aagctgacga ttttgcgact tataaggcag agcagggctt ggctatggag gtcgatgacc
     1441 ttctcttcat ccaagattat ttcaaatcaa tcggacgtgt gccaactgag actgagttga
     1501 aagttttgga tacttactgg tcagaccact gccgtcacac aacctttgaa actgaattga
     1561 agaatattga tttttcagct tctaaattcc aaaaacaatt gcagacgact tatgacaaat
     1621 atatcgccat gcgtgatgag cttggccgtt ctgaaaagcc acaaacactt atggatatgg
     1681 cgactatttt tggtcgttat gagcgtgcca acggtcgtct ggacgatatg gaagtctcag
     1741 atgaaatcaa tgcctgctca gttgagattg aagtagatgt tgatgatgtg aaagagcctt
     1801 ggctcctcat gtttaagaac gagactcaca atcacccaac agaaattgag ccattcggtg
     1861 gagcggcgac ttgtatcggt ggtgctattc gtgacccatt gtcaggacgt tcatacgttt
     1921 atcaggctat gcgtatttca ggcgcaggcg atatcacgac tccgattgcg gaaacacgtg
     1981 ctggtaaatt gccacaacaa gttatttcta aaactgcggc gcacggctat tcttcatatg
     2041 gtaaccaaat tggacttgcg acaacttatg tgcgtgagta cttccaccct ggcttcgtag
     2101 ccaaacgcat ggagcttgga gctgtggtcg gagcggcacc taaggaaaat gtggttcgtg
     2161 aaaaaccaga agcaggtgat gtggtaatct tgcttggtgg taaaacaggg cgtgacggtg
     2221 tcggcggtgc gacaggttca tctaaggttc aaacggttga gtctgtggaa acagctggcg
     2281 cagaggtaca aaaagggaat gccatcgaag agcgtaagat tcaacgtctc ttccgtgatg
     2341 gtgaagtgac tcgtctcatc aaaaaatcaa acgactttgg tgctggtggt gtctgtgttg
     2401 ccatcggtga attggctgac ggtcttgaaa ttgatttgga caaggtgcct cttaaatacc
     2461 aaggtcttaa tggtactgaa attgcaatct cagaatctca agagcgtatg tcagtcgttg
     2521 ttcgtccaag tgatgtggat gccttcatcg cagcctgcaa caaggaaaat atcgatgcag
     2581 tcgttgttgc gaccgttact gaaaaaccaa atcttgtcat gacttggaat ggcgaaatca
     2641 tcgttgattt ggaacgccgt ttccttgata ccaatggtgt ccgtgttgtt gttgatgtta
     2701 aagtcgttga caaggacttg acagttccag aagcacgcac aacatcagca gagacacttg
     2761 aagcagatac gcttaaggtc ttgtctgacc tcaaccacgc tagtcaaaaa ggtcttcaaa
     2821 ctatctttga ctcatctgtt ggtcgttcaa ccgttaacca cccaatcggt ggtcgttacc
     2881 aaatcacacc gacagaaagt tctgttcaaa aattgccagt tcaacatggt gtgacaacaa
     2941 ctgcatctgt tatggctcaa ggttacaatc cttatattgc agagtggtca ccttatcacg
     3001 gtgctgccta tgctgtcatt gaagcgacag ctcgcttggt agcaacgggt gctgactggt
     3061 ctcgtgcacg tttctcttac caagagtact ttgagcgtat ggataaacag gcagagcgtt
     3121 ttggtcagcc agtatcagct cttcttggtt ctattgaggc tcagattcaa cttggtttgc
     3181 catcaatcgg cggtaaggac tctatgtctg gtactttcga agacttgaca gtaccaccaa
     3241 ccttggtagc tttcggcgtg acaacagcgg acagccgcaa ggttctctct cctgagttta
     3301 aagcggctgg cgaaaacatt tactatatcc caggtcaagc tatttcagaa gatattgatt
     3361 ttgaccttat caaggataac tttagccagt ttgaagctat tcaagctcaa cataagatta
     3421 cagctgcctc agccgctaaa tacggtggtg tcctagaaag tcttgctctc atgacttttg
     3481 gtaaccgtat cggtgcttct gttgaaattg cagagcttga cagcagcttg acagctcaac
     3541 tcggaggttt tgtctttaca tcagctgagg aaattgctga cgcggtgaaa atcggtcaaa
     3601 ctcaggcaga ctttacagtc actgtcaatg gaaatgacct tgctggcgct ggccttctag
     3661 cagccttcga aggcaaattg gaagaggttt acccaacaga attcgaacag gcagacgctc
     3721 ttgaagaagt tcctgctgtg gtatcagatg ctgttatcaa ggctaaggaa acaattgaaa
     3781 aaccggtggt ttacattcca gtcttccctg gtaccaactc agagtacgat tcagctaagg
     3841 cctttgaaca ggttggatct agcgtcaact tagtaccatt tgtaaccttg aatgaggctg
     3901 ctattactga atcagttgac actatggttg ctaatattgc taaggcaaat atcatcttct
     3961 ttgctggagg tttctcagca gcagatgaac cagatggctc tgctaagttt atcgtcaata
     4021 tcttgcttaa cgagaaggtg cgcgcagcta ttgacagctt catcgaaaat ggaggcctta
     4081 tcatcggtat ctgtaatggt ttccaagccc ttgttaaatc aggtcttctt ccatacggaa
     4141 acttcgaaga agctggtgag acaagtccaa ctctcttcta taacgatgcg aaccaacacg
     4201 ttgccaagat ggttgagact cgtatcgcaa ataccaactc accttggttg gcaggagttg
     4261 aggtcggcga tattcatgcc attccagttt cacatggtga aggtaaattt gttgtcagcg
     4321 cttctgaatt tgcagagcta agagacaatg gtcaaatctg gagccaatat gtggactttg
     4381 acggacaacc atctatggat tctaaataca atccaaacgg ctctgtcaat gccatcgaag
     4441 ggattaccag caagaatggt caaatcatcg gtaagatggg acactcagaa cgctgggaag
     4501 acggactctt ccaaaatatc cctggtaaca aagaccaaac cctctttgca agtgctgtaa
     4561 aatactttac agggaagtaa aaaggttcag tgaacctttt tagccctcgc cttgaattag
     4621 tgaagggcga ggttagaaag aatctcgctt aatttttgag aaatagtaaa cacgggcgat
     4681 aagttgtgcg aaaaactttc tattttcgct ttacttgaca gcctttgtat cgaggtaaaa
     4741 atgacatacg aagtaaaatc tctaaatgaa gaatgtggag tctttggtat ctggggacat
     4801 cctcaggcag ctcaagtcac ttactttggg cttcatagcc ttcaacatcg cggtcaagaa
     4861 ggagctggta ttgtttcaaa tgacaatggg aaactctatg gttatcgaaa tgttgggctc
     4921 ctttctgaag tttttaagaa tcaatctgaa ttagataatt taactgggaa tgcggctatt
     4981 ggacatgttc ggtatgctac tgcaggttct gcagatattc gcaatattca gccttttctt
     5041 tataaatttc atgacgggca atttgcttta tgccataatg gtaatttgac aaatgctatt
     5101 tccttaagga aagaattaga aaagcaaggt gcaattttca atgcctcctc agatactgaa
     5161 attttaatgc atttgattcg tcgaagccat aacccaaatt tcataggaaa ggtaaaagaa
     5221 gctctaaata cagtaaaggg tggctttgcc tatctactga tgacagaaaa taaactcatt
     5281 gctgctcttg accctaatgc ctttcgtcct ttgtcaattg gacaaatgca aaatggtgcc
     5341 tgggttattt ccagtgagac ctgtgctttt gaggtggtag gcgcaaaatg ggttagagat
     5401 gttgaacctg gcgaagttat tcttatagac gatagtggta ttcaatgtaa tcgttatact
     5461 gatgaaacgc aactggcaat ttgttcgatg gaatatatct attttgcaag gccggattca
     5521 actatacatg gtgttaatgt tcatacggct cgaaaaaata tgggaaagca tcttgcacaa
     5581 gaatttaaac aggatgctga tattgtaatt ggtgtcccaa attcgtcctt atcggctgct
     5641 atgggctttg ctgaagaatc cggattacca aatgagatgg gtcttgtaaa aaatcagtat
     5701 acgcagcgaa cctttattca accgacacaa gaattaaggg aacaaggtgt tcgaatgaaa
     5761 ctatcagcgg tatctggtgt tgtcaaagga aagcgcgttg ttatgattga tgactcaatt
     5821 gtaagaggaa cgacttctag aaggattgtc ggattattaa gagaagcagg agctagtgaa
     5881 gtacatgttg ctatagctag tccagaatta aagtatcctt gtttttatgg tattgatatt
     5941 caaacaagac gagaattaat ttcagcaaat cacgctgctg acgaagtgtg tgatattatt
     6001 ggcgcagata gtctgaccta tctctcacta gatgggttga ttgaatcaat tggactcgaa
     6061 acaaaagcac caaatggtgg tttatgcgta gcttactttg atggacatta tccaacaccg
     6121 ctttatgatt atgaagaaga atacctcaga agtttagaag aaaaaacaag tttttatatt
     6181 caaaaagtga aataagctct gctaattata taaggagaaa acatgtctga aaaaaatgct
     6241 tatgcaaaat ctggtgttga tgttgaagct ggttatgaag tggttgaaag aataaaaaaa
     6301 cacgttgctc gtacagaacg tgcgggagtc atgggagctc taggtggctt tggtgggatg
     6361 tttgacttga gtaaaacagg agttagagag cctgttttgg tctcagggac agacggtgtt
     6421 ggcacaaaac tcatgcttgc tatcaagtac gacaagcacg acacaatcgg tcaagactgt
     6481 gttgccatgt gtgtcaatga tattattgca gcaggtgctg agccccttta cttccttgac
     6541 tacgtagcga caggaaaaaa taatccagtc aaatttgaag aagttgtttc tggcgttgca
     6601 gaaggttgtg ttcaagcagg agcagcactc attggaggtg agaccgctga aatgcctggg
     6661 atgtatggcg aagatgatta tgaccttgct ggctttgctg ttggtgtggc tgaaaaatct
     6721 cagctcatcg acggttcaaa agtaaaggaa ggcgatattc ttttgggact tgcttcaagt
     6781 ggtatccatt caaacggtta ttctttggta cgtcgtgtct ttgctgacta tactggtaaa
     6841 gagctgcttc cagaacttga aggaaaacaa cttaaggatg tccttcttga gccaactcgt
     6901 atttatgtta gagcagctct gccattaatc aaggaagaac tagtcaacgg tatcggccac
     6961 atcacaggtg gtggctttat cgagaatgtt cctcgtatgt ttgcagatga tttggctgcg
     7021 gaaatcgatg aggacaaggt gccagtgctt ccgattttca aggcgcttga aaaatatggt
     7081 gacatcaagc acgaagaaat gtttgaaatc ttcaatatgg gtgtcggtct tatgctagct
     7141 gttagtcctg aaaatgttaa ccgcgtcaaa gagctcttgg atgaaccagt ttatgaaatc
     7201 ggtcgtatca tcaagaaagc agacgatagc gtggtgatta aataagtcac taaattttat
     7261 aagaaaggag tgtttagtta gtttgcctaa ctgaacacgg gattaaattt ctaggaaaaa
     7321 agataaaatg acttagacgc aagcgtcgtt gttcgttttc ctatttttct acgaaatttt
     7381 tcggcaagcc gaatcatccc tttgtatcga atatgaaaat cgctgttttt gcttctggta
     7441 atggttccaa ctttcaggtc atagcagagc agtttccagt tagttttgtc ttttcagatc
     7501 atcgtgatgc ctatgtttta gagcgtgctc agaatttagc cattccaagc ttcgcttttg
     7561 aactcaagga gtttgagaat aaggcggctt acgagcaagc catcgttgat ttgttggaca
     7621 aacacgagat tgatttggtc tgtctaacgg gctatatgaa gattgttgga gaaaccttac
     7681 tcttggccta tgaggggcgt attatcaata ttcacccagc ctacctgcct gaatttccag
     7741 gtgcccacgg tatcgaggat gcttgggaag ctggtgttga ccagtctggc gtgaccatcc
     7801 actgggttga ctctggtgtg gataccggtc aggtcatcca acaagtgcgc gtgccacgcc
     7861 tagcagacga tagcctagaa agctttgaaa cccgtatcca tgaaaccgaa tatcaactct
     7921 acccagctgt cttagatagc ttgggagtgg agaggaaagt aatctagcct ttatcttaaa
     7981 attttaggta aagttaggaa agatagtaaa gaagaattaa cgttccaaaa agaaaggaat
     8041 tgaactcgtc tggaaggcac agaaaaaaga taaacatctc ctaggcgcaa gcgtcttcgt
     8101 cgagtttcct atttttcctt ggccttctag tcggacttgg tatcttaaat atgactaaac
     8161 gtgctttaat ctcagtgtct gacaagtcag gaattgttga ctttgcaaaa gaattgaaaa
     8221 acttgggttg ggatattatc tcaactggtg ggactaaggt tgcccttgac gatgctggtg
     8281 ttgagaccat tgccatcgac gatgtgactg gattcccaga gatgatggac ggtcgtgtta
     8341 agaccctcca cccaaacatt cacggtgggc ttttggctcg tcgcgacgct gacagccacc
     8401 ttcaggctgc taaggacaac aatatcgagc tgattgacct cgtggttgtc aacctctatc
     8461 ccttcaagga gactatcctt cgtccagaca taacctatga tttggcggtg gaaaacatcg
     8521 acatcggcgg tccatcaatg cttcgctcag ccgctaaaaa tcacgctagc gtgaccgttg
     8581 tggctgaccc agcggactat gcgactgttt tgggagaatt ggctgacgct ggtcagacga
     8641 catttgaaac gcgtcaacgc ttggcagcta aggtctttcg tcacacagca gcctacgacg
     8701 ctttgattgc tgagtacttc acaactcaag tgggagaggc taagcctgaa aaattaacca
     8761 tcacttacga ccttaaacag gctatgcgtt acggagaaaa tccacaacaa gacgctgatt
     8821 tctatcaaaa agccttgcca acagactact caattgcttc tgctaaacag ctcaacggaa
     8881 aagaattgtc cttcaataat atccgtgatg ttgatgcagc aatccgtatt atccgtgatt
     8941 tcaaagaccg tccgacagtg gttgccctca aacacatgaa cccatgtggt atcggacagg
     9001 ctgatgatat tgagactgct tgggattacg cttatgaagc tgacccagtt tcaatctttg
     9061 gtggaattgt cgtccttaac cgtgaagttg acgcagcgac agccaagaag atgcacccta
     9121 tctttttgga aatcatcatc gcaccatcat actcagaaga agcgctagct attctcacaa
     9181 ataaaaagaa aaacttgcga atccttgagt tgccgtttga tgcccaagct gccagcgaag
     9241 tggaagctga gtacactggc gtagttggtg gacttttggt gcaaaaccaa gacgttgtgg
     9301 ctgaaaatcc atctgactgg caagtggtga cagaccgcca accaacagaa caagaggcga
     9361 ctgcccttga gtttgcctgg aaggctatca agtatgttaa gtctaacggg attattatta
     9421 ctaacgatca catgacgctt ggactcggtg caggtcaaac caaccgtgtc ggctcagtca
     9481 agattgctat cgagcaggct aaagaccacc ttgacggtgc cgttctagca tcagatgcct
     9541 tcttcccatt tgcggacaac attgaagaaa tcgctgccgc agggatcaaa gcaatcatcc
     9601 aaccaggtgg ttcagttcgt gaccaagact ctattgacgc cgcaaacaaa catggcttga
     9661 ccatgatctt cacaggtgtg agacatttta ggcattaata aaaaaatgtg gtctaattaa
     9721 aaccacattt ttttattaaa agaaaatata agttaactat aatttgttag ctttatcagc
     9781 atttacccat gttccacgag atccgatttg aacataaata ccattacttg gttgatcaat
     9841 ttttaatact ttataactac cagtgacggt aaaatattca cccacacgga gaatttgatc
     9901 tcctaaaact tttccttggt tatctgtttc atctaatggt gtgggatcaa tccagtttag
     9961 tggagttggg tctcctccgg ctaattcttt attaacgatc aaattattaa caagctgatc
    10021 tacacgaaaa acgccaggga aggtaacagt atcaccgacc ttaatggaag gttttgtatt
    10081 ttcattttga accacagact gtgcgggctc tttaatggga atatagcgtc ggtttccaga
    10141 aaaactgagg tagctaagcc atgtataacc tccagcagtc acgactttat cgtaataaac
    10201 agattgacct gcttcatagt aagcaagatc agggctatcg atactggttt gtcctttgac
    10261 tggtaatctg gttgtaaagt gataagttcc agaggggtca aatgaagctt gagaaatgtg
    10321 ttttagttgt cttgggtagg aatgacttgt ctgagatgat aagtctttaa aatggatata
    10381 accacttacc tgagattttg gaatttgacg cttatggtat ctttcagggc cttgtccagc
    10441 gttgtaatta tactcttcga tagtgacagt gtctccacgg atatcagcta cccatgctac
    10501 atgaccgtaa gcagcatttg actgataagc gtttttatca aaccaagcga tagcccctat
    10561 gcttggtgtc ttattcacag gataaccctg atttttcgcg atatgtcccc acgtgcaggc
    10621 attaccgtag cctttaggta actgaaaacc attagcagag cttaaacgaa aagctgcaaa
    10681 agaagtgcat tggcggatat acatgttcca cgaatcgatt ccattgcctt ttttccactt
    10741 actcggatag ttatcgccta aaacagctgc atgaacaaga ttttcctgtt gcgaaataag
    10801 tgtagatggc atagtaggta ctagaccatt aaaacctaaa aggattactc ctgagaccaa
    10861 aaaacgatga aattttttca ttaattacct cctgtaactt attattcgaa agcaagaaac
    10921 aaaaaatgtt atttttagat gattattttg aaaattggct ttacttgata ttaaataact
    10981 gtttgattgg ctaatagagt gttccttatt tca
//
LOCUS       DAUCXI010000051        10634 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.051, whole genome shotgun sequence.
ACCESSION   DAUCXI010000051 DAUCXI010000000
VERSION     DAUCXI010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10634
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.051"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..850
                     /locus_tag="VGY43_001530"
     CDS             <1..850
                     /locus_tag="VGY43_001530"
                     /inference="COORDINATES: protein motif:HMM:NF013550.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_164232585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEQ4302698.1"
                     /translation="PVGPRGAQGLRGEAGPEGPQGPAGKDGEDGAKGETGPAGPRGEQ
                     GLRGETGPEGPQGKTGPAGPAGPRGEQGLQGDRGEVGPRGEQGPAGPAGKDGEKGDQG
                     PMGPRGDRGEAGPAGKDGERGPVGPAGKDGQDGKDGLPGKDGQNGKDGLPGKDGKDGQ
                     DGKDGLPGKDGQDGKDGQPGKPAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQN
                     PSNRGLNKPQTQGGNQLAKTPAAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVA
                     KRQENN"
     gene            1020..1475
                     /gene="msrB"
                     /locus_tag="VGY43_001531"
     CDS             1020..1475
                     /gene="msrB"
                     /locus_tag="VGY43_001531"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEQ4302699.1"
                     /translation="MKRSFPWKHPDELKQRIGDLSYEVTQHAATESPFTGEYDNFFEK
                     GIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAG
                     SHLGHVFSDGPKEAGGLRYCINSAALKFIPYEQMEKEGYAQWLTLFDET"
     gene            1605..2624
                     /locus_tag="VGY43_001532"
     CDS             1605..2624
                     /locus_tag="VGY43_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEQ4302700.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWCLGRLFPIIGAPVFAILLGMLL
                     ALFYEHRDKTKEGISFTSKCILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGSQKWLRLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVS
                     ADSFHSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            2831..3256
                     /locus_tag="VGY43_001533"
     CDS             2831..3256
                     /locus_tag="VGY43_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEQ4302701.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            3283..3774
                     /locus_tag="VGY43_001534"
     CDS             3283..3774
                     /locus_tag="VGY43_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEQ4302702.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRAKDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            3791..4600
                     /locus_tag="VGY43_001535"
     CDS             3791..4600
                     /locus_tag="VGY43_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEQ4302703.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            4597..5424
                     /locus_tag="VGY43_001536"
     CDS             4597..5424
                     /locus_tag="VGY43_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEQ4302704.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            5560..7209
                     /locus_tag="VGY43_001537"
     CDS             5560..7209
                     /locus_tag="VGY43_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ4302705.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDELGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPSQGLLFASNPHLGNVFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            7213..8001
                     /locus_tag="VGY43_001538"
     CDS             7213..8001
                     /locus_tag="VGY43_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4302706.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFEATKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHAH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            7995..9041
                     /locus_tag="VGY43_001539"
     CDS             7995..9041
                     /locus_tag="VGY43_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEQ4302707.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNVAMCIFSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDV
                     YESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAK
                     QFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKIL
                     NTYNRLHEALERGK"
     gene            9156..10553
                     /locus_tag="VGY43_001540"
     CDS             9156..10553
                     /locus_tag="VGY43_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HEQ4302708.1"
                     /translation="MTYQTIYPYTNEVLHTFDNMTDQGVADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEF
                     LMSTPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYDQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQVKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNSNTKV"
BASE COUNT         3247 a         1976 c         2235 g         3176 t
ORIGIN      
        1 tccagtaggt ccacgtggtg cacaagggct acgaggcgaa gccggtcctg aaggcccgca
       61 aggtcctgct ggtaaagatg gtgaagatgg agctaaaggc gaaactggtc cagcaggtcc
      121 acgtggtgaa caagggctac gaggcgagac cggtcctgaa ggcccacaag gcaaaaccgg
      181 cccggcaggt ccagcaggtc cacgtggtga gcaaggcctg caaggtgatc gcggtgaagt
      241 tggaccaaga ggtgaacaag gtcctgctgg gccagctgga aaagatggtg aaaaaggaga
      301 ccagggtcca atgggtccac gtggtgaccg cggcgaagcc ggtcccgccg gaaaagatgg
      361 tgaacgtggt ccagtaggtc cagctggcaa ggacggccaa gatggtaaag atggtcttcc
      421 aggcaaggac ggccaaaacg gtaaagatgg tctcccaggt aaagacggca aggacggcca
      481 agatggcaaa gatggtcttc caggcaagga cggccaagat ggcaaggacg gtcaaccagg
      541 taaaccggct cctaaaacac cagaggtccc tcaaaaacca gataccgcac cacatactcc
      601 aaaaacccct cagatccctg gccaatcaaa agacgtgaca cctgctcctc aaaacccttc
      661 taatagaggt ctaaacaaac cacaaacaca aggtggtaat cagctcgcaa aaacaccagc
      721 agctcacgac acacacagac aattgccagc aacaggcgaa acaaccaatc cattctttac
      781 agcagctgct gtagctatca tgacgacagc tggagttgta gctgttgcaa aacgtcaaga
      841 aaacaactaa tcctcttttt gctacctaac tgatggaaag taaaactcag agagaacctc
      901 aaggttctct ctttttttga atcaagatag tagctctagg tataacgtct tgtctggggt
      961 gctgtgaaca aatcagttac tgctcacctc tttttttggt aaaatataag cactaaaaca
     1021 tcaaaaggag ttttccatgg aaacatccag atgaattaaa acaacgcatt ggtgatcttt
     1081 cttacgaggt cacccagcat gcagcaacag aatctccctt tacaggcgaa tatgataatt
     1141 tttttgagaa gggtatctat gtcgatattg ttagtggtga ggtcttgttt tcatcactgg
     1201 ataaatttaa ttctggctgt ggttggcctg ccttttcaaa acccattgaa aatcgtatgg
     1261 tcacaaacca cgatgactct tcttatggga tgagacgagt tgaggttaaa agccgtgaag
     1321 caggatcgca tttggggcat gtctttagtg acggccccaa agaagctgga ggcttgcgtt
     1381 actgtatcaa ttcagcagct cttaaattca ttccttatga gcagatggaa aaagaaggct
     1441 atgcccagtg gctcacattg tttgatgaga cataacaggg tttcaaaatg actgaaaaag
     1501 aagcgtcagt gattcccata agcactggat tggtgaggcg tacgggtcaa ttttacaagc
     1561 ctttgtaaaa ggtctataat aaggaatgaa aaaaggaggt tagtatgtca actcacttaa
     1621 gaaaacttcc aggcctgtta ctttgtctgc ttttagctct tccagcctgg tgtttagggc
     1681 gcttgtttcc tattattgga gctcctgttt ttgctattct tttaggaatg ttgttagcct
     1741 tgttttatga acatcgtgac aagactaaag agggaattag ttttacatcc aagtgtattt
     1801 tgcaaacagc agtggttttg cttggttttg gattaaacct aacccaagtt atggcagtag
     1861 gcatgcagtc tttacccatt atcatttcaa ctattgcgac agctcttttg gtagcttatg
     1921 gctcacagaa atggctgcgc ttagatgtca atacagccac cttggtgggt gtagggtctt
     1981 ccatttgtgg ggggtctgct attgcagcga cggctcctgt cattaaggca aaggatgatg
     2041 aggttgctaa ggcaatttca gtcatttttc tctttaatat gttagcagct ttgctatttc
     2101 caagtttagg acaattactg ggcttatcta atgaaggttt tgctattttt gctgggacag
     2161 ctgttaacga tacctcttca gtaaccgcga cagcaacagc ttgggatgcc attcaccatt
     2221 ccaatacact agatggcgca accattgtta aattgactcg caccttggct attcttccaa
     2281 ttactttagg cttatccctt taccgagcga aaaaagagca cgacatcgtt acagaagaaa
     2341 actttagcct taggaagtca ttccctcgtt tcatcctctt ctttttatta gcttctctca
     2401 ttacaacgct gatgaccagt ttgggagttt ctgccgatag tttccattcc ctaaaaacct
     2461 tatcaaaatt ctttatcgtg atggctatgg cagcgattgg tttaaacaca aacttggtta
     2521 aattaatcaa gacgggcggt caggctatcc ttttaggagc tatttgctgg gtagctatca
     2581 cccttgtcag tttagccatg caattaagtt tgggcatttg gtaatcagac acgagaaatc
     2641 agtttgactg atttcttttt ttgtatctta tttgtgtaga attgtctaca ttttaaagag
     2701 aatagtgcat tttaaaaacg ttttcatttg ataaaataaa cctatcgtta aaccagttca
     2761 gtaaagacaa ctggttgaga taagcaatta ccgtttattc agcggttttt gttaatagag
     2821 gaggatagga atgaaacgaa aatttctcat tgggagtcac ggcagactag ccagtggttt
     2881 gcaaagctct attgacattt tagcaggtat gggacaggca cttgaaacca ttgatgctta
     2941 tgttgatgat agtgactaca ctagccagat tgatgacttt atcgctgggg tagcagcaga
     3001 tgagcagggc cttattttta ctgatttgtt aggcggcagt gtgaatcaga aaatggtaac
     3061 cgctgtaatg aacagtggca aagacaatat ctttttaatc acaaacagta acttagccac
     3121 tttattgtcg ttggtatttt taaaaccagg cgaagcgctt actaaagatg aaattgtaac
     3181 cgttattaat gaatcgcaag ttcagttagt ggatttggtc cctgagacaa attcagaaga
     3241 tgactttttt gattaatatc ttaatatcta ggaggaagac aaatgattac ccaaattcgt
     3301 gttgacgacc gtttgattca cgggcaagtg gcagttgtat ggaccaaaga gttaaatgcg
     3361 ccgcttttag tagtggctaa tgatgaagct gcaaaaaatg aaatcacaca aatgacgctt
     3421 aaaatggctg tgccaaacgg catgaaactg cttattcgtt cagttgaaga ctcgattaag
     3481 ctctttaatg atccacgcgc caaagacaag cgtatctttg tgattgtcaa ttctgttaaa
     3541 gatgcttgtg ccattgctaa agaagttcca gacttagaag ctgttaatgt ggctaatgtg
     3601 gggcgctttg ataagtcaga cccagcaagc aaagtcaaag tgacaccaag tcttttactt
     3661 aacccagaag aaatggcagc cgcaaaggaa ttagtcagtt taccagaact tgatgtcttt
     3721 aaccaagtct taccatcaaa taccaaggtc catttgagcc aattagtcaa ctaaagagag
     3781 gtaaaaaagt atgttagtac cagcaacaat ggcagcttta gctgtattga tttgttttgg
     3841 gggaaattat ttaaccggtc aaagcatgat ggaaagaccc ctagtagttg gactggtcac
     3901 aggtcttctt ttaggagata tgaaggtcgg tatcttaatg ggggcctctc tagaagctct
     3961 tttcctagga aatgtgaata ttgggggtgt tattgcagct gagcctgtaa cagcgactgc
     4021 catggcaaca acctttacca ttatttcaca tattgaccaa aaagcagcca tgaccctagc
     4081 tgttccaatt ggaatgttag cagcctttgt ggttatgttt ttgaaaaacg tcttcatgaa
     4141 tatctttgct ccaatggttg ataaagctgc agcagctaac catcaaggta aactagtgat
     4201 gctccactat ggcacttgga ttatctatta cttaatcatt gcctctattt ctttcattgg
     4261 tattttagta ggtagtggac ctgttaatgc ctttgtggaa cacattcctc aaaatctcat
     4321 gaatggcttg agtgctgcgg gaggcctcct tccagctgtc ggttttgcca tgctgatgaa
     4381 attattgtgg accaacaaat tagctgtttt ttacctattg ggctttgtct taacagctta
     4441 tttgaaatta ccagcggttg cagttgctgc cctaggagca gttatttgcg tcattagttc
     4501 ccaacgtgat ctagaattag acgcaattac tagaggtgca attagtaaac aaacaacctt
     4561 tgactctaaa gaatcagaag aggaggactt cttcgcatga catcacaaga taatttgact
     4621 aaagaagacc gtaaaatgct tcgctcagtc ttttggcgct catggacgat gaatgccagt
     4681 cgtactgggg caacacaata ccacgcagta ggggttattt acactttact accagtcatc
     4741 aatcgttttt ataagactga taaggataaa gcagaggcac tggtccgtca tacaacatgg
     4801 ttcaatgcca ccatgcacat caataacttt atcatgggtc ttgtggcatc gatggaaaag
     4861 aaaaacagtg aagatcctga ttttgatgct agtgctatta cggcggtaaa agcatctcta
     4921 atgggaccta tttccggcgt tggagattcc ttcttctggg gaattttaag ggttattgcg
     4981 gcaggtatcg ggatttcctt ggcaagtgca ggctcagcca tgggagctgt tgtcttctta
     5041 ctcttgtaca atattcctgc ttttattatt cactactata gcctttatgg tggttattct
     5101 gtaggtgcag gatttatcaa aaaactttac gaatctggtg gtataaaaat cgtcactaaa
     5161 acctcaagta tgcttgggtt aatgatggta ggctcaatga cggcttcaaa tgtaaaattt
     5221 aaaacgattc ttacagttgc tgcgaaaggt gccaaagaag cagcttctat tcaagattac
     5281 cttgaccaat tgtttattgg tattgtacca ttaatggtaa cactagcagc tttttggctt
     5341 ctacgaaaga aagtgaatat caactggatt atgtttggta tcatgttcct tggcattatc
     5401 cttggacttt taggtatttg ctaataatct cctagcaata aaggtaagta agacaagttt
     5461 tcttgttttg cttacctttt tccttttaag atgatgagac ttgctttgat gaaaaacgta
     5521 gtagcattaa gaaatttgtt ataatgaaag gagcttaaga tgcgaggtga acaggtggaa
     5581 gaacatttta aaaaacaatt acaagatgat atttctagac atttttcgta ccaatcgtta
     5641 atgttatcat tgttgctaat tggtcttttt attatttttt cattagcgcc acaacaatta
     5701 ggcctctatc gtgatatcaa tgccactgca actcgttatc accgtttgat tagcaaacaa
     5761 gaagccttgc tggatgaatt agggaaaaat agcttactac cttttttaaa taaaaacctc
     5821 agcactgctg atttaagcaa gcactatttt catttgcgcc atagcagcca aacgtcacca
     5881 gaacttttac tattttcacc tagtcaaggc cttttatttg ctagtaaccc acatttagga
     5941 aatgttttta gtaaatctgt ttatattcaa gaagtcttga gagcagctca tcctccaaaa
     6001 accttgttta aagttgctat ggatagtgaa gatggtcact acttgatgat cattaagcca
     6061 atgattgatc aaaaccaact aaagggatat gcttttttag tgatgagtgg caaagatttt
     6121 cttcatccta caaaaacatt gacgtcagag ttggtcattg ctgataagct ggacaacacg
     6181 tttacgtttt ccaatcgtga gtttatagca tctagtctag ataagatcaa tagccagtat
     6241 ttacaccatt attttgtttt tcaagataat cgagccttta tcacaagaaa ggttgcctta
     6301 caaggaggtc tttggcttta catgtatagg cccttgattc caatggtatc ggtgatgtta
     6361 ttttcactta tttcatcagc tgttatcttt gtgatcttgc aacgtaaatc aagtggttta
     6421 gctaaccgaa ttgcagctaa aaattcaaga gcaatcaatc aaatggttag agatatgagt
     6481 gcgatctctc ggcaagaaaa aagacgtatt gaccttgaga gtcaagatga atttcaatat
     6541 ttatctgatc aaatcaatca aatggtagag cgattgcaac agttacatga taaaacgtta
     6601 gatttggaaa ctcaaaaatt attatttgaa aaacggatgt tagaagctca attcaatccg
     6661 catttcctct acaatacgct agaaaccatt ttgattacga gccattatga ttctgcccta
     6721 acagaaaaaa ttgttatcca attgacaaaa ttgttgcggt atagtctcac ggattctagc
     6781 aaacctgtct tgctcaaaga tgatttaagt gtcatcgagt cttatttagt gattaatcag
     6841 gtgcggtttg aagaattgca atatagcatt aacctatccc cagaccttga tagtcttgca
     6901 gtgcctaaat tgttcttgtt acctttgata gaaaatgcca tcaaatatgg cttgaaagaa
     6961 cgacacgatg tcaagattaa cattgcttgt tattatcaag atgaccacat tattttttct
     7021 gtgcgagata atggttcggg aattgatgct catcaccaaa aagtgattcg agagcaattg
     7081 gaagctggag agtcacacca tgggttaatt aactcttatc gtcggcttaa gtatcatttt
     7141 tcagaagtat ccttggtttt tgatcaaggt gataaacagt ttaatgttag ctaccatgtt
     7201 aaggagtagt ctatgtacaa attagtcatt attgaagatg aacatattat taggaaatgg
     7261 ttgcgatacg ctattgatta taaagcttta gatattttgg tcattggcga ggctaaagat
     7321 ggcaaagaag gagctgtttt aatcaaagag agtcaaccag atatcgtttt aaccgatatt
     7381 aacatgccca tcatgacagc ttttgacatg tttgaagcaa caaaagatca aacttacgcc
     7441 aaaattattt tatctggcta tgccgatttt ccaaatgcaa ggtctgccat acactacggt
     7501 gtacttgaat ttttaacaaa accgattgaa aaagcagctc tttgggaatg tcttcaaacc
     7561 attattgcta aaatagaaaa gcaaaagggg tctaatcaaa aaacagatgc ttgcgtctat
     7621 attcccttac cccagatgac tgatcagatt cctgaagtag tcaaagatat tttggagtgg
     7681 gtacatgctc attttcaaga caagatcagc acgagccgcc tagctcatga cttagggtat
     7741 agtgagagtt atatctatca aaatatcaaa aagcatcttc agatgccttt aagtgattac
     7801 attaatcaat atcggattaa tcaggcaatt caattgatgc aacaagaacc agatttaatg
     7861 gtatatgaaa tagcacaagc tgtaggtatt tatgactatc gctattttga tagggttttt
     7921 aaaaagtatc taggacaaac tgtaaaggct tttaaagaag agcattttat gaaagatacc
     7981 gataggagta agccatgtta aaactcaaac gcaaatggct attaagcttt ttgttagtaa
     8041 taattatttt agcaatcgtt aacgttgcaa tgtgtatatt ctcatcgtca aaaaaagata
     8101 gtgctaaaga attagttatc ttgactccta atagccaaac tattttaaca gggactattc
     8161 cagcctttga ggaaaagtat ggggttaaag taagattaat ccaaggtggg acgggccaac
     8221 ttattgatca attaggtcga aaagataagc cattaaacgc tgatattttc tttggtggca
     8281 attacactca atttgaaagc cataaagatt tatttgaatc ctatgtttct ccgcaggttt
     8341 ctactgtcat ttcagattac caattgccta gtcatcgtgc aaccccatat acgatcaatg
     8401 gcagtgtact gattgttaat aacgaattag caagaggact tcatattacc agttatgagg
     8461 atttgctaca accagcttta aaaggcaaaa ttgcttttgc tgacccaaat agctcatcta
     8521 gcgctttttc acaattaaca aacatcttac tggctaaagg aggctatacg agctcagaag
     8581 cttgggagta tgtgaaacgt ttattactgt ctatgaattc tatcagagca acaagttctt
     8641 cagatgttta cgaatctgtt gcagaaggta aaatgattgt tggtttgacc tatgaagatc
     8701 cttgcatcaa tctgcaaaaa agcggtgcaa acgtttcgat tgtttatcct gatgagggga
     8761 cagtatttgt tccgtcatca gtcgctatta tcaaaaaagc aaaggcaatg aaagaagcta
     8821 agcaatttat taattttatt ttatcatcag atgtacaaaa tgcctttggg cagtcaacta
     8881 gtaatagacc tatccgacga gatgctcaaa caagtcatga aatgaaacca ttagatgaaa
     8941 ttattacttt aaaagaagat tacggatatg ttactagaca taagaaaaaa atattgaata
     9001 cctataatcg actacatgaa gcattagaaa gaggaaagta gactctaggc ttgttgttgc
     9061 tatactagta gtgttacaaa atagcgtagt cattttttga aatcgatttc ataatctggt
     9121 agactaaggt tatcacgaaa aggaggctat atgtgatgac ttatcaaact atttaccctt
     9181 atacaaatga agtccttcat acatttgata atatgaccga ccaaggtgtg gcagatgtcc
     9241 ttgaaagagc tcaccttctc tataaaaaat ggcgcaagga agatcattta gaagaacgta
     9301 aagcccagct tcatcaagtg gctaatattc ttcgccgtga ccgcgataaa tatgctgaaa
     9361 tcatgaccaa agacatggga aaactgttca cagaagccca aggtgaagta gacctttgtg
     9421 ccgatattgc tgattactac gctgataagg cagatgaatt tttgatgtct acgccactag
     9481 aaacagattc aggtcaagct tactatttga aacaatcaac tggtgttatc ctagctgttg
     9541 agccttggaa tttcccttac tatcaaatca tgcgggtttt tgcgccaaac tttattgttg
     9601 ggaacccaat ggttttaaaa cacgcgtcca tttgcccacg ctctgcccaa tctttcgaag
     9661 aattagttct tgaagctggt gctgaagcag gtagtattac caatttgttt atttcttatg
     9721 accaagtatc acaagtgatt gctgataaac gtgtggttgg tgtctgcttg acaggttccg
     9781 aacgtggagg agctagcatt gcagaagaag ctggtaaaaa cttgaaaaaa acaacccttg
     9841 aattgggtgg agatgatgcc tttattatcc ttgatgacgc ggattgggat caattagaga
     9901 aggtgcttta cttctctcgt ctctacaatg caggacaagt atgtacctca tcgaaacgtt
     9961 ttatcgtgct tgacaaagac tatgaccgtt tcaaagaatt attaacaaaa gtcttcaaaa
    10021 cagctaaatg gggtgaccca atggatcccg aaacgacgtt ggcaccatta tcatcagctc
    10081 aagttaaagc agatgttctt gaccaaatta agttggcctt ggatcatggt gcggagttgg
    10141 tttatggtgg tgaagcgatt gatcatccag gtcattttgt catgccaacc attattgctg
    10201 gcctcacaaa agacaaccct atttactatc aagaaatctt tggcccagtc ggtgaaatct
    10261 acaaagtgtc ttctgaagaa gaagcgattg aagtggcgaa tgattctaac tatggccttg
    10321 gaggtactat ctttagtagc aatcaagaac atgcgaaagc cgtagctgct aaaattgaaa
    10381 ctggtatgtc ttttatcaac tcaggttgga caagtcttcc agaactccca tttggtggga
    10441 ttaaacattc aggctatggt cgtgaattga gtgagcttgg ctttacatct tttgtgaatg
    10501 aacaccttat ctatattccg aataaaacga ataatagcaa tactaaagtt tgatctagat
    10561 tgttaaagga gatctgctcg ccttaataaa caatcaaggc gttacactct tcttttttaa
    10621 agtcaaaatt ttaa
//
LOCUS       DAUCXI010000052        10450 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.052, whole genome shotgun sequence.
ACCESSION   DAUCXI010000052 DAUCXI010000000
VERSION     DAUCXI010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10450
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.052"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            69..1874
                     /gene="pepF"
                     /locus_tag="VGY43_001541"
     CDS             69..1874
                     /gene="pepF"
                     /locus_tag="VGY43_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEQ4302709.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFA
                     GHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSIRQAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNYFIQYEWA
                     RIPHFYYNYYVYQYATGFVAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
     gene            2249..3445
                     /locus_tag="VGY43_001542"
     CDS             2249..3445
                     /locus_tag="VGY43_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEQ4302710.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILQETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTSAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTSMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            3511..4218
                     /locus_tag="VGY43_001543"
     CDS             3511..4218
                     /locus_tag="VGY43_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEQ4302711.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQTTGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEIFR
                     LLRVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADIVLPD"
     gene            4281..5336
                     /gene="prsA"
                     /locus_tag="VGY43_001544"
     CDS             4281..5336
                     /gene="prsA"
                     /locus_tag="VGY43_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEQ4302712.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKAEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEQTQTSS
                     AAEPTETEAQTQEPAAQ"
     gene            5723..8341
                     /gene="alaS"
                     /locus_tag="VGY43_001545"
     CDS             5723..8341
                     /gene="alaS"
                     /locus_tag="VGY43_001545"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEQ4302713.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRN
                     EAIGWGFELLTSPEWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYNPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLAQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEESRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DTGRIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAEIV"
     gene            8702..8917
                     /locus_tag="VGY43_001546"
     CDS             8702..8917
                     /locus_tag="VGY43_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4302714.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            8914..9675
                     /locus_tag="VGY43_001547"
     CDS             8914..9675
                     /locus_tag="VGY43_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEQ4302715.1"
                     /translation="MKKKKNSFLRLLKMLLLSSLAGGIIGGMVGAFLGYHGERLDQLT
                     FLKDDVINLIILLNRLVVVTGLTLSFVFLTQLKKETAVYNTIEENDYSENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            9694..10389
                     /locus_tag="VGY43_001548"
     CDS             9694..10389
                     /locus_tag="VGY43_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEQ4302716.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIVGTLVNQL
                     WSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
BASE COUNT         3282 a         1776 c         2159 g         3233 t
ORIGIN      
        1 tgcaaacgct tttttcacca aaatattatg ttaaaatgga tagtaataga aaatgagaag
       61 gagatgttat gactgataat cgcagccatt tagaagaaaa atacacttgg gatttgagca
      121 ctatttttgc aacagataag gattgggaag ctgaagtcag tgacttagct actgaagttg
      181 aggcatctaa aggttttgct ggtcatttgc tggattctag tgctaatttg ttaaaggtta
      241 caaaaacata tttagaattg gctcgtcgtg ttgagaaagt ctatgtctat gctcatatga
      301 aaaatgatca agacacgact gttgctaaat atcaagaata tcaggctaag gcttctggct
      361 tgtatgctaa atttagcgaa gtgttttcat tctatgaccc agaagttatg gcattgagtc
      421 aggaagatta ccaagctttt cttgcggaaa cacctgattt aaaaaggtat catcatttct
      481 ttgacaaatt gttccagaca cgtgaccatg tgctcagcca ggctgaagag gaattattag
      541 caggagccca agaaattttc aacggcgctg aagaaacctt tagtattctt gataacgctg
      601 atattgtctt tccagtagtt aaaaatgata agggggaaga tgttgaatta acccatggta
      661 acttcattag cctaatggaa tctaaggacc gtagcattcg ccaagctgct tatgaagcca
      721 tgtatagtac ttatgaacag ttccaacata cttacgctaa aaccttgcaa accaatgtga
      781 aagtgcaaaa ctataaggcg cgtgttcata aatacgattc agcacgtcaa gctgccatgg
      841 ctgctaactt tattccagaa gctgtttacg acactttatt agaaacggtt aacaaacatt
      901 taccactctt acaccgttat ttgaaattgc gtcaagaggt tcttggttta gacgatttga
      961 agatgtatga tgtttacaca ccattatctg aaacagattt agccattggt tatgatgagg
     1021 ctttggaaaa ggctgagaag gttttggctg tttttggtaa agattacgca gatcgtgtgc
     1081 atcgtgcttt taccgaacgt tggattgatg ttcatgtcaa taaagggaag cgttctggag
     1141 cttattcggg tggttcctat gataccaatg cctttatgct attaaactgg caagatacct
     1201 tagacaatct atacacttta gttcatgaaa ctgggcacag tttgcattct actttcactc
     1261 gtgaaacaca gccttatgtg tatggagatt acagtatttt cttggcagaa attgcatcca
     1321 caacgaatga aaatattatg acagaagctc tcttaaatga ggttcaagat gagaaagaac
     1381 gctttgccat tttaaaccat tacctcgatg gtttccgtgg aacagttttc cgtcaaaccc
     1441 aatttgctga gtttgaacat gccattcatc aagctgatca aaaaggagaa gtgttaacaa
     1501 gtgaatacct taaccagcta tacgctgatt taaatgaaaa atattatggt ttaagtaaaa
     1561 aagataatta ttttattcag tatgaatggg cacgtattcc tcatttctat tacaattatt
     1621 atgtttacca atatgcaaca ggttttgtag ctgcaagcta tttagcggat aagattgtgc
     1681 atggcacaca agacgatatc gatcattact tggcctacct caagtcagga aattctgatt
     1741 acccacttga agtgattgct aaagcaggcg ttgatatggc aaaaggtgat tatttggaag
     1801 ccgcctttaa agtctttgac gaacgtctaa cagaacttga agtactcgtg tccaaaggca
     1861 tacacaaaag ctaaaatcac aaaagtcaag gacaaaaaga gtttaggatt gatagaaatg
     1921 gagattcaca gttggtgtga atctccattt ctatcggtca ttttcttttt atattttagt
     1981 ggattatcag tcctgaaaag caggcttcat tgaccttagt ttgacggttt cttttttgtc
     2041 ttttttattg tgtggtcact cacttaaata aaaccaatag ttgagtaagg cgcttcagat
     2101 taacgctatt ctattgtttt agagataatg ttcgcataaa acatattttt attatatttg
     2161 acattttata aaagagataa tagaattaaa atactaacat ttatgttttt ttaaaaataa
     2221 acgttcgtat aataaaaagg agtttttcat ggaaaaaaca aaacgttata tcattgcaac
     2281 agcagggata cttctccact taatgttggg atcgacctat gcttggagtg tttatcgtaa
     2341 tccaatttta caagagaccg gttgggacca agctcctgtc gcttttgcct tttctttagc
     2401 tattttttgt ttaggtttat ctgctgcttt tatgggaaat ttagttgaac aatatggtcc
     2461 tcgtctaacc ggaacggtgt cagctattct ttatgcttct ggaaatatgc tgactggttt
     2521 agcgattgat cgtaaagaaa tttggctttt atatattggt tatggtgtta ttggtggctt
     2581 aggacttgga gcgggatata tcacaccgat atcaactatt ataaaatggt ttccagataa
     2641 aagaggcatg gcaacagggt ttgctattat ggggtttggt tttgcgtctt tattaacaag
     2701 tccgattgcc cagtggctaa ttgaaacaga aggtttggta gcaacatttt accttttagg
     2761 gctgatttat ctaatagtta tgctttttgc ttctcaattg ataataaaac caacttctgc
     2821 tgagatagct atactagata aaaaaagatt acaaaataac agttatttaa tcgaaggaat
     2881 gaccgctaaa gaagcactta aaacaaaatc attttattgt ctttgggtaa ttttatttat
     2941 caatatcaca tgtggcttag gacttatctc agttgttgcg ccaatggcac aagatctaac
     3001 tagtatgagt ccagaaatgt cagcaattgt ggttggtgct atggggattt ttaacggttt
     3061 cggtcgttta gtgtgggcta gtttgtcaga ctatattgga cgccgtgtga cagtaatact
     3121 tttattttta gtaagcataa ttatgactat tagtttaata tttgcacata gttccctaat
     3181 tttcatgata agcattgcca cccttatgac ttgttatggt gcgggttttt ctctcattcc
     3241 gccttattta agtgatcttt ttggggcaaa ggaactggct acattacatg ggtatatatt
     3301 gacagcttgg gcaatagctg cattaactgg acctatgtta ttatctatca ctgttgaatg
     3361 gactcataat tatcttctta ccttatgtgt ttttattgtc ttatacattt taggattaat
     3421 ggtagcatta aggttaaaga aatgatgtcc tataaaaaat ttaaaagtaa accctagcaa
     3481 agcctagggt ttttttatat aattaggttt atggttaaat catacagtaa aacagcaaat
     3541 cataatatgc gtcgtcctgt tgtcaaagaa gagcttgttc attatatgcg aacacggcag
     3601 aagcaaacca caggtttttt agcagagtta gagcaattcg caagacaaga aaacattcct
     3661 attattcagc ctgaggtcgt ggcttatttc aggtttttat tgcaaagctt acagccaaaa
     3721 cacattttgg agattggcac agccattggt ttttctgcgc ttttaatggc tgaaaatgca
     3781 ccagatgcga cgattgtgac tattgatcgt aatcgagaga tgatcgattt tgctaaagca
     3841 aattttgcta agtacgacag tcgccaacag atccgcctgt tagaaggaga tgcagcagat
     3901 atattatcta cacttgaagg aaattttgac tttgtgttta tggattccgc caaatccaaa
     3961 tatattgtct ttctaccaga gattttcaga ctgttaagag tcggtggtgt agtcattttg
     4021 gatgatgtct ttcaaggagg tgacattaca aaaccgatcg aagacattcg acgaggtcag
     4081 cgtactattt atcgtggctt acagtctttg tttgatgcca ccttaactca tccaaaccta
     4141 acaactagcc tggtccctct tagtgatgga ttattaatga ttcgtaaaaa tcaagcagat
     4201 attgtattac cagattaagt aacattgata aatttatgtt ataataaatt agttaaagat
     4261 aaaaaggagc tcagaagtaa atgaaaaact caaataaact cattgctagt gttgtgacat
     4321 tggcctcagt gatggcttta gcagcttgtc aatcaactaa tgacaatact aaggttattt
     4381 cgatgaaagg tgatacaatt agcgttagtg atttttacaa tgaaacaaaa aacacagaag
     4441 tatcgcaaaa agcgatgcta aatctggtaa ttagtcgtgt ttttgaagct caatatggtg
     4501 ataaggtttc aaaaaaagaa gttgaaaagg cgtatcataa aacagctgaa cagtatggcg
     4561 cttcattctc tgctgctttg gcacaatcaa gcttgacacc tgagactttt aagcgtcaga
     4621 tccgctcttc aaaattagta gaatatgcgg ttaaagaagc agctaaaaaa gaattgacaa
     4681 cacaagaata taagaaagca tatgaatctt atactccaac aatggcagtc gaaatgatta
     4741 ctttagataa tgaagagaca gctaaatcag tcttagagga actaaaagcc gaaggcgcag
     4801 actttacagc tattgctaaa gaaaaaacaa caacacctga gaaaaaagtg acctataaat
     4861 ttgattcagg cgcgacaaat gtaccgactg atgtcgtaaa agcggcttca agtttgaatg
     4921 agggtggcat atcagacgtt atctcggttt tagatccaac ttcttatcaa aagaagtttt
     4981 acattgttaa ggtgactaaa aaagcagaaa aaaaatcaga ttggcaagaa tataagaaac
     5041 gtttgaaagc tatcattata gctgaaaaat caaaagatat gaatttccaa aacaaggtta
     5101 ttgcaaatgc attggataaa gctaatgtaa aaattaaaga caaagctttt gctaatattt
     5161 tggcgcaata tgcaaatctt ggtcaaaaaa ctaaagctgc aagtgaaagt tcaacaacca
     5221 gcgaatcatc aaaagctgca gaagagaacc catcagaatc agagcaaaca cagacatcat
     5281 cagctgcaga accaactgag actgaggctc agacgcaaga gccagctgca caataagtag
     5341 gattttattg actaatcagt taaaaaaact tataataatt tagttaagaa ttgtttatca
     5401 aggattagat acagaaaagt gacggttgct gcgagtcatt gataattaga taaacatgct
     5461 acttaacttt acaacaattg atatcgtaaa ttaagaatga caagttcatt gaatagaggt
     5521 ggtaccgcgg ttttcgccct ctgtgagatg gacttgtttt gtattgagga ctatttgaaa
     5581 tcaacgaaag gaatagagta gactaggctg ccaggcttat agctgatctc ctagcaagaa
     5641 agacgagctg tgtcaactgg tgtgattaca ttactagctt cagcataaca ctgtttttct
     5701 tactctttgt atctaaattt ttatgaaaga attatcgtct gcacaaatcc gccaaatgtg
     5761 gttggatttc tggaaatcta aaggacattg cgttgagcct tcagctaact tggttcctgt
     5821 gaatgaccca acgcttcttt ggatcaactc aggtgttgca accttgaaaa aatactttga
     5881 tggttcagtg attccagaaa atccacgtat taccaatgca caaaaatcaa ttcgtactaa
     5941 tgatattgaa aatgttggta aaacagcacg tcaccatact atgtttgaaa tgcttggtaa
     6001 cttctcaatt ggagactatt tccgtaatga agctattggg tggggatttg aactcttgac
     6061 aagtcctgaa tggtttgact ttcctaagga caagctctac atgacttatt acccagatga
     6121 caaggattcg tataaccgtt ggattgcttg tggcgttgaa ccaagtcact tggtgccgat
     6181 cgaggataac ttctgggaaa tcggtgctgg tccttcaggt ccagatacgg agattttctt
     6241 cgatcgtggt gaagatttcg atccagaaaa tatcggactt cgcctcttgg ctgaagatat
     6301 cgaaaacgat cgttacatcg aaatctggaa catcgttctc tcacaattca atgctgaccc
     6361 agccgtacca cgttcagaat acaaagaatt accaaacaaa aacattgata caggtgctgg
     6421 tcttgaacgt cttgcagctg ttatgcaagg ggcaaaaaca aactttgaaa ctgacctttt
     6481 catgccaatc atccgtgaag tagagaagtt gtcaggtaaa acttataatc cagatggcga
     6541 caacatgagt ttcaaggtta tcgctgacca catccgtgcg ctttcatttg ctatcggtga
     6601 tggtgcgctt cctggaaatg aaggtcgtgg ttacgttctt cgtcgtcttc tccgtcgtgc
     6661 ggttatgcat ggccgccgtc ttggcatcaa cgaaactttc ctttacaaat tggttccgac
     6721 tgttggacaa atcatggaaa gctactaccc agaagtgctt gaaaaacgtg attttatcga
     6781 gaaaatcgtt aaacgtgagg aagaaacatt tgctcgtact atcgatgcag gtagcggtca
     6841 cttagattca ttgcttgcgc agcttaaggc tgaaggtaag gatactcttg aaggtaaaga
     6901 tatcttcaaa ctttatgata cttatggatt cccggttgaa ttgacagagg aattggcaga
     6961 agatgcaggc tacaagattg accacgaagg ctttaagtca gccatgaaag aacaacaaga
     7021 ccgtgcgcgt gcagctgttg ttaagggtgg ttcaatgggg atgcaaaatg aaaccctagc
     7081 tggtattgtt gaagaatcac gattcgaata cgacacatat agtcttgaat caagtctttc
     7141 agtcatcatc gctgataatg aacgtaccga agctgtttca gaaggtcaag cccttcttgt
     7201 ctttgctcaa acaccattct atgctgaaat gggtggacag gttgctgaca caggtagaat
     7261 caaaaatgat aagggtgaca cagttgctga ggttgttgat gttcaaaaag caccaaatgg
     7321 tcaacctcta cacactgtaa acgttttagc atcactttca gttggaacaa actacacact
     7381 tgaaatcaac aaagagcgtc gtttggctgt tgagaaaaac cacacagcta ctcacttgct
     7441 ccatgcagct cttcacaatg ttatcggtga acacgcaact caggctggtt cattgaacga
     7501 agaagaattc ttgcgctttg attttactca ctttgaagca gtaagcaatg aggaacttcg
     7561 tcacattgaa caagaagtta atgagcaaat ttggaacgct cttacaatca caacgactga
     7621 aactgacgtt gaaaccgcaa aagagatggg agcaatggcg ctttttggtg agaaatatgg
     7681 taaagtggtt cgtgtggttc aaattggtaa ttattctgtt gaactttgtg gtggaactca
     7741 cttaaataat tcttcagaaa tcggtctctt caagattgtc aaagaagaag gtattggttc
     7801 aggcactcgt cgtattattg cagttactgg tagacaagct tttgaagctt atcgtaacca
     7861 agaggatgcc ctaaaagaga tcgctgctac tgtaaaagct ccgcaattga aagatgcagc
     7921 agctaaagta caagctctta gcgactcgct tcgtgatctt caaaaagaaa atgcagaact
     7981 taaagaaaaa gcagcagctg cagcagctgg tgatgtcttt aaagatgttc aagaagctaa
     8041 gggcgtgcgc ttcattgcta gtcaagttga tgttgcagat gcaggggcac ttcgtacatt
     8101 tgctgataac tggaaacaaa aagactactc tgatgtgctt gttctcgtag cagctattgg
     8161 tgagaaggtt aatgtccttg ttgcaagcaa aaccaaagat gtccacgctg gtaacatgat
     8221 caaagaattg gcaccaattg tagcaggtcg tggtggaggt aaaccagaca tggctatggc
     8281 aggtggtagc gatgcaagta aaattgcaga gctgctagca gcagttgctg aaatagtgta
     8341 aatccataaa aaaccaagtt atttagaact tggtttttta tatttgaaat gactaccatc
     8401 ataacctttt tgactattat cgttgtcaaa aagaaaaaga tatgttacaa ttatagtaac
     8461 aaatagacat gaggaggtgt tagagaaaat gacacatggt atcaaactta agaggcagat
     8521 ttgcttatgg gcaagtatcc tgactctttt cattttaagt tatcatctta tcagggtaat
     8581 ctggtttgga gtacccttga gttatctggt tttgggcttt acaggactag ccttgctgtt
     8641 gaatactttt tcttatttta gaaagtaagt tataagttaa agaagaatga aggagatggc
     8701 aatggaggtt attcttaaaa atcggctcaa agaattacga gccagagatg gaattaatca
     8761 aacggaaatg gctaaactgg caggagtatc gaggcagacc atcagtctca ttgagcgtaa
     8821 cgagtacacc ccatcagtta taattgccat gaaaattgca aaggtatttc aggaaccagt
     8881 tgaagaggtg tttcgtctag tggaggtcga ggaatgaaaa agaagaagaa tagtttttta
     8941 cgcttgttaa aaatgttatt gctatcaagt ttggcgggag ggattatagg tggcatggtt
     9001 ggagcctttt taggttacca tggagagaga ttagatcagc tcacgttcct aaaagatgat
     9061 gtgattaacc tgattatctt attaaatcgt ctagtagttg tcacaggcct cacactttct
     9121 tttgtttttt taacgcaact gaaaaaagag acagctgttt ataacacaat tgaagagaat
     9181 gattattctg aaaatggtta ccgtcagctg aataaaaagc atgcttatac catgttattg
     9241 attgccgtag cttctatttt atccatgtgc aatgtgctac ttggtctgac cttaactaat
     9301 gattcacagc atgctatgct ggccattccg cttctggata tccttttatt attaatggtc
     9361 attccttttc aagctttagc catgaaacgt tacaatgcca ttcggggaac tgatgttcct
     9421 tattttccaa atttgaaaga attaaaacat aatatcatgg ctctagatga ggcagagtta
     9481 caagcctatc ataagacatc gtttgaaagt gtgttgtcat taaatggagt catcatccct
     9541 tccttgtatg tgattttatt ttttgtctat ctattcactg gtcaagtgga gttaacagcc
     9601 atcttagttt tggtgttaat tcagctctat ttactcgtta agagtgcaac aatgaccaga
     9661 caattttacc gttagcctaa aaggagactg tttatgaaag gattcattaa ttatttaaaa
     9721 atagcagtgc tcattattct ggctatggtt ttcaatgtcc ttccgatgat tttattgcaa
     9781 aagcaacacg atattcctat ggtgcttaat tggggaattg gtattttcta cttggttatt
     9841 gttggaagtg tccttattgt attatggcgt ctttatcaag ctaagcaaga cacccctatt
     9901 aaacagcaaa aaatgagatt ggttgactgg ggttatttag cattattttg gttaatcatc
     9961 cgtgtgatag ctattgtagg tacccttgtt aaccagctat ggtctggtca acaagtgagt
    10021 gctaatgatg ctgcaataca taccttagct agacttatca aaggtggttt cccgctttat
    10081 actgccctat ttgtacttgt gatagctttt atcgctccta ttatggaaga actagtcttt
    10141 agaggatttc ctatgattga tctcttcaaa ggaaaatcac ttaaggtggc aggtttagtg
    10201 acctctcttg tttttgcttt accacatgcc accaatagtg ttgaatttat catgtacagc
    10261 tgtatgggca tttttctctt tgttgcctat caaagacgag gaaacttaaa agacgctatc
    10321 ttgttacata tttttaataa cttgattgaa gtcattttgt taatgtcaat aggcttggga
    10381 gtcatataat aaaaagcttc gaatgactga actgcacccc aaaagttgga caaaaaaatc
    10441 taacatttgg
//
LOCUS       DAUCXI010000053        10208 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.053, whole genome shotgun sequence.
ACCESSION   DAUCXI010000053 DAUCXI010000000
VERSION     DAUCXI010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10208
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.053"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            101..1021
                     /gene="lmb"
                     /locus_tag="VGY43_001549"
     CDS             101..1021
                     /gene="lmb"
                     /locus_tag="VGY43_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HEQ4302717.1"
                     /translation="MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            1034..3505
                     /locus_tag="VGY43_001550"
     CDS             1034..3505
                     /locus_tag="VGY43_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEQ4302718.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGLATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYHFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARSSDYRPTPAPGRRKAPIPDVTPNP
                     GQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGL
                     IFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSEHSK
                     PSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHY
                     IGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVG
                     YMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLP
                     MHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHE
                     ESGSVIPNVTPFDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETF
                     VWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQAD
                     KSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQP
                     EGVQFYNKNGELVTYDIKTLQQINP"
     gene            3674..3874
                     /locus_tag="VGY43_001551"
     CDS             3674..3874
                     /locus_tag="VGY43_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEQ4302719.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(3954..4580)
                     /locus_tag="VGY43_001552"
     CDS             complement(3954..4580)
                     /locus_tag="VGY43_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302720.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIIISHDFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(4564..5367)
                     /locus_tag="VGY43_001553"
     CDS             complement(4564..5367)
                     /locus_tag="VGY43_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302721.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIRQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSRGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG"
     gene            complement(5379..6200)
                     /locus_tag="VGY43_001554"
     CDS             complement(5379..6200)
                     /locus_tag="VGY43_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302722.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(6197..7174)
                     /locus_tag="VGY43_001555"
     CDS             complement(6197..7174)
                     /locus_tag="VGY43_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302723.1"
                     /translation="MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIKSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV"
     gene            complement(7287..8915)
                     /locus_tag="VGY43_001556"
     CDS             complement(7287..8915)
                     /locus_tag="VGY43_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEQ4302724.1"
                     /translation="MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDEIV
                     VSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSF
                     DLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQVNIHLTEAHS
                     TFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFK
                     KWTWVLLDENTALAALESGDVDMIYATPELASKKVKGTRLLDIPSNDVRGLSLPYVKK
                     GVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWN
                     PKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVA
                     EQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNIT
                     FYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIG
                     DKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK"
     gene            9094..9318
                     /locus_tag="VGY43_001557"
     CDS             9094..9318
                     /locus_tag="VGY43_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302725.1"
                     /translation="MTYFRLKKELNWLLRSKGIVVYEGNQKLQIAINTGKNNSEKVFF
                     DTFFEVVRAAATFSTAKNICFGLGLLRSQK"
     gene            complement(9644..10208)
                     /locus_tag="VGY43_001558"
                     /pseudo
     CDS             complement(9644..10208)
                     /locus_tag="VGY43_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="exotoxin"
BASE COUNT         3374 a         1918 c         1978 g         2938 t
ORIGIN      
        1 aaaagatggt agttgccatt gacaaagcat tgataaagga gtaaaattaa ctggttaata
       61 actggttaat aactggttaa attataattg aggaggtact atgaaaaaag gtttttttct
      121 catggctatg gtcgtgagtt tagtaatgat agcagggtgt gataagtcag caaaccccaa
      181 acagcctacg caaggcatgt cagttgtaac cagcttttac ccaatgtatg cgatgacaaa
      241 agaagtatct ggagacctaa atgatgtgag gatgatccaa tcaggtgcag gcattcattc
      301 ctttgaaccg tctgtaaatg atgtggcagc tatttatgac gcggatttgt ttgtttacca
      361 ttcacatact ttagaagctt gggcaaggga tctagaccct aatttaaaaa aatcaaaggt
      421 tgatgtgttt gaagcgtcaa aacctctgac actagataga gtcaaagggc tagaagatat
      481 ggaagtcaca caaggcattg accctgcgac actttatgac ccacatacct ggacagatcc
      541 cgttttagct ggtgaggaag ctgttaatat cgctaaagag ctaggacgtt tggatcctaa
      601 acacaaagac agttacacta aaaaggctaa ggctttcaaa aaagaagcag agcaactaac
      661 tgaagaatac actcaaaaat ttaaaaaggt gcgctcaaaa acattcgtga cgcagcacac
      721 ggcattttct tatctggcta aacgattcgg cttgaaacaa cttggtatct cgggtatttc
      781 tccagagcaa gagccctctc ctcgccaatt gaaagaaatt caagactttg tcaaagaata
      841 caacgtcaag actatttttg cagaagacaa tgtcaatccc aaaattgctc atgctattgc
      901 gaaatcaaca ggagctaaag taaagacatt aagtccactt gaagctgctc caagcggaaa
      961 caagacatat ctagaaaatc ttagagcaaa tttggaagtg ctctatcaac agttgaagta
     1021 aaggagatta ttagtgaaga aaacatatgg ttatatcggc tcagttgctg ctattttact
     1081 agctactcat attggaagtt accagcttgg taagcatcat atgggtctag caacaaagga
     1141 caatcagatt gcctatattg atgatagcaa aggtaaggca aaagccccta aaacaaacaa
     1201 aacgatggat caaatcagtg ctgaagaagg catctctgct gaacagatcg tagtcaaaat
     1261 tactgaccaa ggttatgtga cctcacacgg tgaccattat catttttaca atgggaaagt
     1321 tccttatgat gcgattatta gtgaagagtt gttgatgacg gatcctaatt accattttaa
     1381 acaatcagac gttatcaatg aaatcttaga cggttacgtt attaaagtca atggcaacta
     1441 ttatgtttac ctcaagccag gtagtaagcg caaaaacatt cgaaccaaac aacaaattgc
     1501 tgagcaagta gccaaaggaa ctaaagaagc taaagaaaaa ggtttagctc aagtggccca
     1561 tctcagtaaa gaagaagttg cggcagtcaa tgaagcaaaa agacaaggac gctatactac
     1621 agacgatggc tatattttta gtccgacaga tatcattgat gatttaggag atgcttattt
     1681 agtacctcat ggtaatcact atcattatat tcctaaaaaa gatttgtctc caagtgagct
     1741 agctgctgca caagcctact ggagtcaaaa acaaggtcga ggtgctagat cgtctgatta
     1801 ccgcccgaca ccagccccag gtcgtaggaa agccccaatt cctgatgtga cgcctaaccc
     1861 tggacaaggc catcagccag ataacggtgg ctatcatcca gcgcctccta ggccaaatga
     1921 tgcgtcacaa aacaaacacc aaagagatga gtttaaagga aaaaccttta aggaactttt
     1981 agatcaacta caccgtcttg atttgaaata ccgtcatgtg gaagaagatg ggttgatttt
     2041 tgaaccgact caagtgatca aatcaaacgc ttttgggtat gtggtgcctc atggagatca
     2101 ttatcatatt atcccaagaa gtcagttatc acctcttgaa atggaattag cagatcggta
     2161 cttagccggc caaactgagg acaatgactc aggttcagag cactcaaaac catcagataa
     2221 agaagtgaca catacctttc ttggtcatcg catcaaagct tacggaaaag gcttagatgg
     2281 taaaccatat gatacgagtg atgcttatgt ttttagtaaa gaatccattc attcagtgga
     2341 taaatcagga gttacagcta aacacggaga tcatttccac tatataggat ttggagaact
     2401 tgaacaatat gagttggatg aggtcgctaa ctgggtgaaa gcaaaaggtc aagctgatga
     2461 gcttgctgct gctttggatc aggaacaagg caaagaaaaa ccactctttg acactaaaaa
     2521 agtgagtcgc aaagtaacaa aagatggtaa agtgggctat atgatgccaa aagatggcaa
     2581 ggactatttc tatgctcgtg atcaacttga tttgactcag attgcctttg ccgaacaaga
     2641 actaatgctt aaagataaga agcattaccg ttatgacatt gttgacacag gtattgagcc
     2701 acgacttgct gtagatgtgt caagtctgcc gatgcatgct ggtaatgcta cttacgatac
     2761 tggaagttcg tttgttatcc ctcatattga tcatatccat gtcgttccgt attcatggtt
     2821 gacgcgcgat cagattgcaa caatcaagta tgtgatgcaa caccccgaag ttcgtccgga
     2881 tgtatggtct aagccagggc atgaagagtc aggttcggtc attccaaatg ttacgccttt
     2941 tgataaacgt gctggtatgc caaactggca aattatccat tctgctgaag aagttcaaaa
     3001 agccctagca gaaggtcgtt ttgcaacacc agacggctat attttcgatc cacgagatgt
     3061 tttggccaaa gaaacttttg tatggaaaga tggctccttt agcatcccaa gagcagatgg
     3121 cagttcattg agaaccatta ataaatctga tctatcccaa gctgagtggc aacaagctca
     3181 agagttattg gcaaagaaaa acgctggtga tgctactgat acggataaac ccaaagaaaa
     3241 gcaacaggca gataagagca atgaaaacca acagccaagt gaagccagta aagaagaaga
     3301 aaaagaatca gatgacttta tagacagttt accagactat ggtctagata gagcaaccct
     3361 agaagatcat atcaatcaat tagcacaaaa agctaatatc gatcctaagt atctcatttt
     3421 ccaaccagaa ggtgtccaat tttataataa aaatggtgaa ttggtaactt atgatatcaa
     3481 gacacttcaa caaataaacc cttaaccaaa agaagatctc attattaaag cactgcttta
     3541 tcaaagcaag ttacggtgat tttgaagtca ttttatgtaa cgagtagtga taaaagttgg
     3601 ataatagcgg ttttcttttg caaagaaatg gtatccatgt tagaataata aaaaaaagag
     3661 gaggattcta atcatgtcag aagaaaaatt aaaatcaaaa attgagcaag catctggtgg
     3721 cctaaaagaa ggtgctggta agttgacagg tgataaagag ctagaagcaa aaggatttgt
     3781 tgaaaaaaca attgctaaag gcaaagaact tgcagacgat gcaaaagaag cggttgaagg
     3841 tgctgtagat gccgttaagg aaaaattaaa ataattaaaa aaccagctgt aagctggttt
     3901 tttaatggtg tgattttgtt agaaaaagac tcaataggta ataaccatag atgttaggta
     3961 tgcttgaaca gttgagtacg attctcttca atcatatagc acgcgtcaca aagtttttct
     4021 aacatatcaa aatcatgact aataatgatg agacctaaat ttctatcctt tacaatctcc
     4081 aacaggcttt tccatacact agcttgtgta atgctatcca acatagtagt catttcatct
     4141 gcaataaggt atttcgtctc tggatgtaat gaacgcacaa tcgaaaagcg ttgcaattcc
     4201 cctcccgaga gttcactagg gcgacgcttt agccattttt cttgaatgcc aaaagcatct
     4261 cgcaaatctt gacttggata gtaggcttct tccaaacttt ttttcatagg ccataaagga
     4321 ttcatggttt gttcaggatg ttgttggata agttgcacag gtctaaatgc tttgttaggc
     4381 aaatgactgc catcaactaa tacttcacca gatttaggct gcaaaaaacc ggcaagcact
     4441 ctggataaac tcgtttttcc acacccactt tgtccaaata tccctaagat ttgaccaggt
     4501 gctacctcta aatcaatctc cttaaaaagc cattgatctt ttttatgata aaagccaagc
     4561 tttttagcct ctaaggtcat gagtaactcc tttcaaaaag tcttgctgag ggagtgtgcg
     4621 ccataaacgt ctcgcaaatt ctgtttgtaa ttgctctcca cctctgctaa aaaagctagc
     4681 tggggctgtt tcaatagctt ttccctcttt aaaaatagtt atacgatccg caatttgact
     4741 agctgctaca atatcatgag tgataaagat gacgcttatt cctttatctg caaaagagcg
     4801 tagttgatct aaaaccattt gcagagcatc tggatgtaat ccaggggtgg gctcatccgc
     4861 aataatcaaa gaaaccgtat cactaataca cgttgtaaac aaaacacgtc ggagcattcc
     4921 gccagaaagt tggaaaggat acaagtcacc atcactttct tttaatccaa actgttgaaa
     4981 caatccttct tgagtagcct tagcattttc tgagataccc aagcgcacct gatgtttgac
     5041 tttcatagat ggatctaaat aattaacgga ttgtggaatc aacgtcattt cttttcctcg
     5101 caactgtctg atgcgtttag aagttagtga ttgaccacga taaatcatat ctcctgttac
     5161 agctgcattt ttaggaagaa tatccataat agcatgtgct aataaactct tgcctgaacc
     5221 actagcacct ataatagcta ataactcacc ttttttaact tctaaattca gcgcttgtat
     5281 cggtgtggat tgaaatggtt ttaaaaatct tccgtattga gtgaaggtga tggagaggtc
     5341 tttaatgctt aataatgttt ctgtcatatc tctacctcct aaaaatgatc cgtttgaggg
     5401 taaaagagtt tctttaaaga ttctccgata gtatcaaagg cattgacaac caaaataaga
     5461 taaaggcctg gaaaaatcac caaccaccaa ttgccaagag agatatgctt agctgcctct
     5521 gacagaatga taccaaccga aggttgttcg gcagaaaggc caaatcctaa gaaagtcatg
     5581 gatgcttcat gcaagatgac gtgcggaaat aagaggataa acccaatgaa aatttgagaa
     5641 gcaatcaaag gcaggatatg atgcctcaca atataataag gcgtttttcc catgctttta
     5701 gagagctgga caaaggcttt attctttaga tcatagactt cattgcggat aagccttgct
     5761 agagagggcc aatgggtaac agccgttgca atgataaccc cttgagcccc tttcccaaca
     5821 acaaaagaaa tgagaatcat aaaaatcaaa tgaggcatac caataaacaa atcaaccaac
     5881 caggctatta ttttatcaat aaggctattt cctagacctg caagcactcc aaaaacggtc
     5941 gcaagaaaga ctcccataag ggcacctaat aagccgactt gtaaagagaa ataaagccct
     6001 ttaatcgttc tgacaaacat atccctacct aaaccatctg ttccaaaaag atggtttaag
     6061 gaaggagcga ggttgcgtaa agctgcattg gtttccaaag gcgtcctata gaaataaagg
     6121 tttaaggcta gaatactaag aatgagagaa atggcgatac ctagttgcca taaaaccatc
     6181 gttcgacgtt tcaatatcat acttttctcc ttaactgtgg attgatgatg ctatttaaaa
     6241 tgtccgcaat aagattgccc gcaaaaacaa ataatgtccc tatcatcaca atagctagaa
     6301 ggagcggtgt atcactttta aggcctgctt cagtgagggt agaccctaag ccaggatatg
     6361 agaaaacttg ctcagcaaga acagatcctc caaacaattc tccaaaatag gaaaaatgca
     6421 gtgtaatagc tggtacgata gcatttctaa gacaatgatg tttaaaaatt tgccactgtg
     6481 tttccccacg cgctctggca aataagacat attcactgga aagcaccgac atcattttag
     6541 ttctcgtatg aagagtgaca ttggcaatgc ctagaatact tagcgtgaaa acaggtaaca
     6601 taaggtgctt aatccgatca gctaacgtaa tatcttgact taaagtgcct atcggagaag
     6661 aaataccaat cgggaaccac cccagctgga cagaaaagat taataaaaaa atgagtccaa
     6721 tccaaaacgt tggtactgat atctgaaggt aagaaaacca cctgacaact cgatcaagta
     6781 atttcccttg atggaaagcg gataacgttc ctaagataaa tccaataaga cccgataaga
     6841 tccaagagag tcccataagt atgaaagaag cacctgcccg tgatttaata atatcactaa
     6901 caggttgccg ataaacgagc gaggtcccta aatgtccctg tatcacattt tttaaccaaa
     6961 taaaatattg gactagagct ggcttatcca agccatagtg gtgagcaatc gctttgtact
     7021 gagcaggggt tagtgatgtg tcataattga cacttgccat gactggatct actggagatt
     7081 gttttaacaa aacgaaggtc aaaacagata ccccaaaaat aagcgtgaca catctgatga
     7141 ttttccagat gataataatg gtagtacgtt tcacaatgaa atctccttaa tcgataagaa
     7201 aaggagccga ggaaacgatc agcacagttt tgtgtatctt gttttctcag actccaaact
     7261 taaagtcgct gtattaacta aacgcgttac ttagttgatt catcccaagt ccactcggca
     7321 atgttagtca ataatgacca atcatgacca tgactgtgga cgccttgttt acctacattg
     7381 atacgtttat caccaatata agtatggtta aggctcacca accatacatt tggcaaatct
     7441 ccaagagtag aagcacctgt tttgccatcc cactgcgcta acttccaata ttcgttagct
     7501 ttgtcaaggt cagaagatgt cattgctttg tcaaggtact tagtcacggt aggattgtta
     7561 taaaacgtaa tattggtcca acctttacct gctaggcttg gatgatgtga ttcataaaat
     7621 tgctgcgcgt gatgacgtcc tccggcataa agtaaggctg agtcatgtga cttcgttgcc
     7681 atttcatccc agttactagc tttgagttta atagtaatcc ctagggcttt ggcttgctct
     7741 gctacttcaa cggctaagtt cgctcgcaat tgatcattag tagggtagta cagatcaaac
     7801 gctgcatcaa ggtcaccttt tttacggcta ccgtctgctt gttctttcca tcccgctttt
     7861 gtcaacaatt gcttagcttt agctacttta ttatctttaa tggctgtttt tggattccaa
     7921 aatggtgttt tatcaataat tgaataagct ggtttaccat aaccatttaa aaccgtatcg
     7981 agaacttttt gtctatttaa accaatagtc aaggctttgc ggattgctgg atcactagtg
     8041 acatcatttc ctacaggata accatcagga gaatcagtga tgacgccttt tttcacataa
     8101 ggtaatgata agccgcgcac atcatttgat ggaatgtcaa ggaggcgagt gcctttgact
     8161 ttcttactag caagttctgg tgtcgcgtag atcatatcaa catcaccaga ttctaaagca
     8221 gctagtgctg tgttttcatc aagtaagacc caagtccact ttttaaagta tggttttttc
     8281 ccatgccaat aagggttacg aacaaaaata gcttgttctc cagccttata ttcttttacc
     8341 atgtaaggtc ctgaaccgat aggattgctc ttatacttat cattgtaatg ttttttaggg
     8401 acgattggga tttcagtcaa ctgtgctgta aatgtcgaat gcgcctcagt caaatggata
     8461 ttgacctgat ttttcccaac tacttcaacg ttcttgatga aggttagatc ccaagccttt
     8521 ccatctgctt tcaacatatc ataagtaaac ttaacatcat cagcagtaac aggctcacca
     8581 tttgagaatt taaaatcatc atgcaagtca aacgaccaag tcagcccatc ttcagagaga
     8641 tggtatgttt tagcaagctc tccttttata tctagttcag gagaacgttt caatagagtg
     8701 ctatgagtga tattcccttc attgtggact ccataacggt cctttggatc gaattcatga
     8761 gggagctttg cccccataga aacgacaatt tcgtcttttg gacgttgttt gcgctgacgt
     8821 tcttttgttt gaggcttttg ttgttgacat gcaactaaaa taagcccagt caaaaataac
     8881 gtgataatag agaagtattt taggtatttt gacacaatca aatctcctta tttctaatta
     8941 ataaataata atagtaacga ctccatctca ttatagcaat aaacaaatag gagggcaatt
     9001 gtttaactgg ttaattagaa tttttgttat tttcaggaag atactcaggg cttttttata
     9061 agttgatgta ttaacaaaag ataaagaggt ttcatgactt attttagatt aaaaaaagaa
     9121 ttaaactggt tactaagaag taaaggaatt gtagtttacg aagggaatca aaaacttcag
     9181 atagctatta atacaggtaa aaataacagt gaaaaagtct tttttgatac tttttttgag
     9241 gtggttcggg cggcagcgac tttctccaca gcaaaaaaca tctgttttgg tcttggctta
     9301 cttcgttcgc agaaatagga aatcgggtat cacattagca gagtagttca tgctttttga
     9361 gcatcacact gggtctgtct acgttctaaa agcttttgtc atttttgtat cataccccct
     9421 acaagtagaa acagcataat aaagaaaatt tataaacaaa aatggctagt attatcaagg
     9481 aatttatcaa tttttgtttt ttaaaattaa tatagaaagt atagcattct agaacaaatt
     9541 tagaacaaaa cctaagtgat ataaaaaaag acatacttac tttttagagg attcaatcta
     9601 tttggaatag cttagtgtat aaaagttata ttgaaaaatt gaattaggag tcaatttcta
     9661 tatctaaatg cccaatttta tctatattga aagatttatt gtctttttat actttaaaaa
     9721 tactttcttt atctctatat cctgtataga aaagatcgaa agaatattta tctgaattat
     9781 catttgtatg aaaaactaat ttaccacttt tgtagctaga accagaagaa tataattgat
     9841 gttgtgctat taaaaatttt ctaaccttta gatcaatttc ttgagctgta actgttgttt
     9901 tgttagttga tatttcgttg taaggaacag agatctgctt tccattaatc cataaattaa
     9961 cagggatatt tttaggtatt gaagtttttt ggtagggtgt tactccgccg tacgtatatg
    10021 ctgtgacttt tccttctgac aagtagttcc aatcaaatgg gacggagaac acagctattt
    10081 tatctccatc tttaaaatca ttggctgcat attcgtccat ttcggagtta ataaaaaaat
    10141 ctctagcatc tctaacatca agtttcttag tcactaagtt atgactggtt ttaaaatcaa
    10201 ttactgta
//
LOCUS       DAUCXI010000054         9301 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.054, whole genome shotgun sequence.
ACCESSION   DAUCXI010000054 DAUCXI010000000
VERSION     DAUCXI010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9301
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.054"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            237..2237
                     /gene="metG"
                     /locus_tag="VGY43_001559"
     CDS             237..2237
                     /gene="metG"
                     /locus_tag="VGY43_001559"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEQ4302726.1"
                     /translation="MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQVIGGIAPSGH
                     EVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRT
                     TFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQANHANFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGAVPAYVDNGT
                     AFDADLSQLIDAQLADYHKHMEAVDYPRALEAVWTIIARTNKYIDETTPWVLAKEDGD
                     KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLEPVSDLSVLALADFPANTK
                     VVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWVPEEVALKSEKDVITFETFDA
                     VEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKSYPNEQELVGKKLQIVA
                     NLKPRKMMKKYISQGMILSAEHGDQLMVLTVDSSVPNGSIIG"
     gene            2732..3745
                     /gene="nrdF"
                     /locus_tag="VGY43_001560"
     CDS             2732..3745
                     /gene="nrdF"
                     /locus_tag="VGY43_001560"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ4302727.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYESPFTDEETRVSPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            3749..4237
                     /gene="nrdI"
                     /locus_tag="VGY43_001561"
     CDS             3749..4237
                     /gene="nrdI"
                     /locus_tag="VGY43_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ4302728.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQINNLITERTHPCHKPMRHT
                     SH"
     gene            4204..6384
                     /gene="nrdE"
                     /locus_tag="VGY43_001562"
     CDS             4204..6384
                     /gene="nrdE"
                     /locus_tag="VGY43_001562"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ4302729.1"
                     /translation="MSQTNASYLSLNALTRFKKPDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKQYLETFEDRAVMNALFLADGDQAFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRAYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVETGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYAFKASCQLA
                     KEKGAFAGFSLSTYADGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQALVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQMTTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECQSCMI"
     gene            complement(6545..7297)
                     /locus_tag="VGY43_001563"
     CDS             complement(6545..7297)
                     /locus_tag="VGY43_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEQ4302730.1"
                     /translation="MLKKRYQLAIVLLLSCFSLIWQTGGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKGAATLIKKRWGKGLVYPRAEQEAMAAYTCQQAGPINTSLDKAKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDQKKLHIEAYFKGSL"
     gene            7756..8208
                     /locus_tag="VGY43_001564"
     CDS             7756..8208
                     /locus_tag="VGY43_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302731.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMARPVKAEVSRSEGAERTEQ
                     QNLFRGPQEDFEEGNDEAGSYTYTWEKDRDFGKQQGLEAGKNGYGPNISRDDISVPVG
                     MQNPDEYKDGYQEGYSEGWHQEHPLLGVVFDVFVSIWGVVSGLFSEAN"
     gene            8741..9139
                     /locus_tag="VGY43_001565"
     CDS             8741..9139
                     /locus_tag="VGY43_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302732.1"
                     /translation="MKTKSKRFLNLATLCLALLGTTLLMTQPVKAEIVKSPEAEQTVM
                     QKNGVTETDNSYQKEWDRGYDEGYKKGNERNSPKKPEHSPVADGSGYSDGYSTGYGAG
                     WYDGHLVEAIIDGLISWFNYIFFGSGGSSE"
BASE COUNT         2755 a         1993 c         2008 g         2545 t
ORIGIN      
        1 gggcacaaaa ggatgaagag aaagttttca tgcgtacggc gtgccctcct ttgattgact
       61 ggttttgctg ccccttaaaa tatgatataa tagactattg atagctgtta cttaacagaa
      121 ggctgataaa aaaggttcca ttagccttga gggttgaatt taaacaggaa aaaacgaaat
      181 cctacactat gcatctcaat catactttca tttgagtatg gttctgaaag gaaactatga
      241 tgaaaaaacc attttacatt acgacaccca tttattaccc atctgggaaa ttacacattg
      301 gttctgccta tacaactatt gcttgtgatg tcttggcacg ctacaagcgc ttgatgggcc
      361 atgaggtctt ttacctcaca ggacttgatg agcacggaca aaagattcaa accaaggcaa
      421 aagaagctgg tattacacct caaacctatg ttgataacat ggcaaaggat gtcaaagccc
      481 tttggcaatt gctagatatt tcctatgaca catttatccg gacaacggac gattaccacg
      541 aagaggtcgt tgctgctgtc tttgaaaaat tgctggcgca agacgacatt taccttggcg
      601 aatactctgg ttggtattct gtctctgatg aggaattttt cactgaaagc caattaaaag
      661 aagtctttag agatgaagac ggtcaggtta ttggaggaat tgccccatca ggtcatgagg
      721 tcgagtgggt ctctgaagaa tcctatttcc tacgccttag caaatacgct gatcgtcttg
      781 tggccttctt taaagagcga cctgacttta tccaaccaga cggtcgtatg aatgaaatgg
      841 tgaaaaactt tatcgagcca ggtctagaag atttggctgt tagccgtact acctttacat
      901 ggggtgtacc tgttccatca gacccaaaac acgtggttta tgtctggatt gatgccctcc
      961 taaactatgc gacagctctt ggttatggtc aagctaatca cgctaacttt gataaattct
     1021 ggaatggaac ggtttttcac atggttggaa aagatatctt gcgtttccac agtatctact
     1081 ggccaatctt actcatgatg cttgatttac caatgccaga ccgcttaatt gctcatggtt
     1141 ggtttgtcat gaaagacggt aaaatgtcta aatcaaaagg caatgtggtc tatccagaaa
     1201 tgttagtaga gcgctttgga ctagatcctc ttcgttatta cctcatgcgt tctttgccag
     1261 tgggttcaga cgggaccttt acccctgaag attatgtggg tcgtatcaac tatgagttag
     1321 ccaacgacct tggcaattta ttgaaccgta ccgttgcgat gatcaacaag tattttgacg
     1381 gcgcggtgcc agcttatgtt gacaatggaa ctgcctttga tgctgactta agtcaactga
     1441 ttgatgctca gctagcagac taccataagc acatggaagc tgtagactac ccacgcgcct
     1501 tggaggctgt ttggactatc attgctcgta ccaacaaata catcgatgaa accactcctt
     1561 gggtgctcgc taaagaagat ggtgacaaag ctcaactagc cagtgtcatg gcacacttag
     1621 cagctagctt gcgcgtggtc gctcatgtga tccaaccctt tatgatggaa acatcagctg
     1681 ctatcatggc ccagcttggt ttggaacctg tttctgattt gtcagttctt gctttagcag
     1741 attttcctgc caatacaaag gtcgttgcca aaggcacacc gattttccca cgtcttgata
     1801 tggaagctga gattgactac atcaaagccc aaatgggtga cagctcagct atttcccaag
     1861 aaaaagaatg ggtccctgaa gaggttgcgc tcaaatctga aaaagacgtc atcacatttg
     1921 aaacctttga tgctgtggaa atccgtgtgg cagaagtcaa ggaagtgtca aaagtggaag
     1981 gttcagaaaa attgctgcgc tttagagtag atgcaggaga cgggcaagac cgtcaaatct
     2041 tgtcaggtat tgccaaatcc taccccaacg aacaagaatt agtgggtaaa aaactacaaa
     2101 ttgttgctaa cctgaaaccg cgtaaaatga tgaaaaaata catcagccaa ggcatgattt
     2161 tatcagcaga gcatggagat cagctaatgg tcttaaccgt tgattcctct gttccaaatg
     2221 gaagtatcat tggctgatgc tgacttatta ttcaaaaaac ctaagcaaga acatgtgctt
     2281 aggttttttt gattgccttc aagaaagacg aataacgaga tgggtgatat ggcagcaaaa
     2341 gcataactat cctaggacct gtcctagtaa gattgctgtg cttttgacaa gtgaacagag
     2401 aggtcttaaa actatatctt gtcataaaaa agattgcaaa acactatatc ttgtgttatt
     2461 atggttttta taaaagttaa gcacgcttaa ctttagccaa acaaaagagg acactagagc
     2521 gtgtcccaca agacagttga gcccttcgct tttttagtag agtaggagtg ctcaagtcaa
     2581 aaagagacat cccatcaaac cattgctgtt tagcaggtct ttttgtgttg ctcaaaaaaa
     2641 caattcctgt ctgtttggcg tctagtgatg acttaggctt agcgctacta gacttttgtt
     2701 tgaaaaatac ctcaagcctt gaaggagaca aatgacccaa cattattatg aacgttcgca
     2761 atccccaatt gaatacgccc tatctgaaac acaaaaacag ttgcgctcca tcaattggaa
     2821 ttaccttaat gatgacaaag atttggaagt gtggaaccgt gtcactcaaa atttttggtt
     2881 gcctgaaaag gttcctgttt ctaatgattt aaattcttgg cgctccttgg gtgaggattg
     2941 gcaacagctc atcacaagga cctacactgg gttgacctta ctagataccg tacaagcaac
     3001 ggttggtgat gtggcacaaa ttcagcattc acaaaccgac cacgaacaag tcatctatac
     3061 gaactttgcc tttatggtgg ggattcatgc ccgctcttac gggacgattt tttcgaccct
     3121 ttgcagcagc gagcaaattg aagaagcaca tgaatgggtg gtctcaacac agagcttgca
     3181 agaccgtgcc cgtgtcttga ttccttacta tacgggtgat gaccctttga aatcaaaagt
     3241 agcagcagct atgatgccag gatttttgct gtatggcggc ttttaccttc ctttttacct
     3301 atcagcacgt ggtaaaatgc caaacacatc tgatatcatc cgcctgattt tacgcgacaa
     3361 agttattcac aactattaca gcggttacaa ataccaacaa aaagtagcac gtcttagccc
     3421 agaaaaacag gctgaaatga aggcctttgt ctttgacttg ctctatgaac tcatcgacct
     3481 tgaaaaagct tacttgagag aactgtatgc aggctttgat ttggcagaag atgctatccg
     3541 ctttagcctt tataacgctg gaaaattcct tcaaaatttg ggatatgagt cgcctttcac
     3601 agatgaagaa acgcgcgttt caccagaagt ttttgctcag ctatcagcgc gtgcagacga
     3661 aaaccatgac tttttctcag gcaatggctc atcttatgtg atggggatca ccgaagaaac
     3721 cacagatgac gattgggagt tttaagaaat ggcagagctg attattgtgt atttttcatc
     3781 taagtccaat aacacccatc gcttcgtcca aaaattaggc ctgcctgctc agcgcatacc
     3841 agtagataat aggccacttg aagtttcaac ccattacctt ttgattgtgc ctacctatgc
     3901 agctggtggc tcagatgcca aaggagccgt ccctaaacaa gtgattcgtt ttttgaataa
     3961 tcctaacaat cgtaaacatt gtaagggagt gatctcttca ggaaatacca attttggcga
     4021 tacctttgcc ttagcaggcc ctatcatttc tcaaaaattg caggtcccct tattacacca
     4081 atttgaacta ttaggcactg ctacagatgt caaaaaggta caggcgattt ttgcccgctt
     4141 aaagcatcac acacacgaca agcaaaaaca aatcaacaac ctgattacag aaaggacaca
     4201 cccatgtcac aaaccaatgc gtcatacctc tcattaaatg cactgacccg ttttaaaaaa
     4261 ccagacggca gctaccattt tgatagcgat aaagaagctg ttaggcgcta cctggaagaa
     4321 catgtctctc ccaatcaaat ggcttttaac tcactagaag ataagctagc ttacctcatc
     4381 aatgaagggt attatgagca ggccattttt gatgcctacc ctaacgacct tatcaaggag
     4441 gcctttcatt atgcctatca acaaggctat cgctttttaa atctcatggg cgctatgaaa
     4501 ttttaccagt cctatgcctt aaaaaccttg gacggtaagc agtatctaga aacatttgaa
     4561 gaccgtgctg tgatgaatgc actcttttta gctgatggag atcaagcttt tgtctttgac
     4621 gtgattgatg ccatcttgca ccgacgcttt caaccagcta ccccaacgtt tttaaatgcc
     4681 ggaaaaaaac gccgtggcga atacatttcg tgctatcttc ttcgtgtcga agacaatatg
     4741 gaatctatct ctcgcgccat cagcaccagc ttgcaactct caaaaagagg aggcggagtc
     4801 gccttgtgtc tcaccaacct cagagaaatc ggagcaccga taaaagggat tgaaaatcag
     4861 gcaacaggca tcgttcctgt catgaaacta ctagaggact ctttttccta tgccaatcaa
     4921 ctaggtcagc gccaaggagc aggtgcggtt taccttcatg cccatcatcc tgaggtcttg
     4981 acctttttag acaccaaacg tgaaaatgcc gatgagaaaa ttcgcattaa gtccctagca
     5041 ttgggacttg tgatcccaga tattaccttc cagttagcca aagaaaacaa agacatggct
     5101 ctcttttcac cctatgatat caagcgtgcc tatggcaagg acatgtcaga catctccatc
     5161 acagaggaat acgataaact gctagccaat ccagccatca aaaagaccta catcagtgct
     5221 agaaagctct ttcagttaat tgcagagcta cattttgagt caggctaccc ttacctcttg
     5281 tttgatgaca cggtcaataa gcgcaaccct catgccaaaa aaggcagaat cgtcatgtct
     5341 aacctgtgtt ctgaaatcgc tcaagtcagc accccaagca ctttcaaaga agatttgagt
     5401 tttgaaacca ttggagagga tatctgctgt aatttagggt ctatcaatat tgcccaggct
     5461 atggcagatg cgccacactt tgaacagctc atcacaacga gcatcagagc acttgatcgt
     5521 gtctctagag tgtctgacct gaattgtgcg ccttctgttg agacaggcaa tgcagccaac
     5581 catgcagtag gattaggcgc catgaaccta catgggtttt tggcaaccaa ccacatctac
     5641 tatgatacaa aagaagccgt tgactttaca gatctgtttt tccatgccat ggcctattat
     5701 gcttttaaag cctcttgcca attagccaaa gaaaaaggcg cttttgcagg attttcgtta
     5761 tcaacctatg cagatggcac ttattttgcc aagtatttgc aagaagatgc caagccacaa
     5821 acagccaagg ttgccacatt gttgcaagat tacggcttca cattgccaac ggtggcggac
     5881 tggcaagccc tagtagcaga tatcaagcag tttggtctag ccaatgcgca cttgctagcg
     5941 gttgctccga caggctccat cagctactta tcatcctgca ctccgagtct acaaccagtc
     6001 gttgctcctg ttgaggtccg aaaagaaggt agcctgggca ggatttacgt ccctgcctat
     6061 cagattgacc aggctaacta tgcttactat gaacgtggtg cctatgaggt cggcccaaaa
     6121 gccatcatcg acgttgtcgc tgctgcccaa aagcacgttg accaagccat ctcattgacc
     6181 ctgtttatga ctgatcaaat gaccacacgt gaccttaacc gctcctatat ccaagctttt
     6241 aagcaaaact gtgcatcgat ctattatgtg cgagtgagac aagacgtcct agcaggcagc
     6301 gaacagtatg acgaggatag tcttgtgaca gctcctggag ctagtgatga gaccaccaca
     6361 gagtgccaaa gctgtatgat ctaacagcta ctagaaagct ctcgtgtccc ctatcacatg
     6421 cataggatca gtgcgctcga ccattcaaga caagcaagca tcagctcttg cttgtctttt
     6481 tttgagcatc agaacgtcaa aaaaaggaca tggagtcctt ttttggtgat cggtgttgag
     6541 gccgtcacaa actgcccttg aaatacgctt ctatgtggag ctttttttgg tcctgtgaca
     6601 cgtaagctcc aacgacctcc agctgacagc ctcttggaaa caagagctca acctctgaag
     6661 gcacagccga ataaggctcg acaaaggctg ccttggcccc ttttttgaca cagatgcgca
     6721 cctccaccgg tcgatgggtc atggcgccat ttttcaaggc tgtcgtgctc ataaaactgt
     6781 gcttggtgta gcgtgtgcca agcttgatct tacaaaggat atgagggtca aactgatggt
     6841 tacggtagta agacgtgaga tcagcgtgtg aaacaccgat atcacgcaaa aacgtctcgt
     6901 atacatagcg gtatactaca atgttccacg ggatgactag ccggtgagtc gcagcatcga
     6961 gctgggccac ctgatccctt agctcaggcg tgagttggct gagctcacct ttggccttgt
     7021 ctaggctggt gttgataggg cctgcctgct ggcaggtata agcagccatc gcctcttgct
     7081 cagcccttgg gtagacgaga cccttgcccc atcgcttttt aatcagtgtc gcagctccct
     7141 tttgatccga aaaggtaaaa taagcaggcg tcccctcaca aaccgcccgc tcatagtgct
     7201 cacagacaaa aagctcgacc aagcccccag tttgccagat cagactaaaa cagctaagaa
     7261 gaaggacaat agcgagttga tagcgctttt ttagcatagt tccccctgac accagcccaa
     7321 aaggctgacc cttcccctag accttttggc tagctcttga caccaccagt ttctcagaca
     7381 ggctaatctt tttgtcatct ctttctccct aaacagactc tcttatcatg atattatgct
     7441 attatgagcg atttgtcaat ccatagtaac cgttttttag ttagataagt aagcttttga
     7501 cctagaggca gacaagagtg gcagtacctg ccgtttgctg tggtggctaa taaggactaa
     7561 cataaaatct caaacgcttt caaaaatagc tcctgagctt aaaaaaggcg aattaccaga
     7621 tttgttgagc ttaagggaga ttgccatgat tttctaatca tttgatggtt aaaatgataa
     7681 aaacatgaac ttgaagtgaa agaatgcgag tagtaaacta gaaccgtatc aaaaataatg
     7741 aaatggagtg attttatgaa aacaaaatca aaacgctttt taaacctagc aaccctttgc
     7801 ttggccctac taggaacaac tttgttaatg gcacgtcccg taaaggcgga ggtgtcaaga
     7861 agcgaaggcg ctgagcgtac agagcagcaa aatcttttta gaggtcctca agaagatttt
     7921 gaagaaggta acgatgaagc cggaagttat acttatacat gggagaaaga tagagatttt
     7981 ggaaaacaac aaggacttga ggctggtaaa aatggttatg gaccgaatat aagtcgggat
     8041 gacatatcag ttcctgtagg tatgcaaaat ccagatgaat acaaagatgg gtatcaagaa
     8101 ggttatagtg aggggtggca tcaggagcat ccacttctag gagttgtatt cgacgttttt
     8161 gtttcgatct ggggcgtagt gagtggtctt ttcagtgaag caaattagtt atagttacgc
     8221 tgttagagag tagtattatc tgttgaaagt actgtaatgt ttaggctaca gcgatatttt
     8281 tggtacatat agctaaaagt actacagtta attttttatc acaagcattt cccacactaa
     8341 tctgctataa ttgggatagt ctctttagta gtcaggccac ctctgatagg ggtggctttt
     8401 ttgggtttta gtgacccgtg tgttgagaaa ggagcatgta cgtcagaaaa gaaagtgttg
     8461 cccgttctaa tatgaaccga cagttattcc ttattaaata gacgcaaata tccacgcttt
     8521 cactgtggtg gttgataaga actaacacaa aatctcaaac gctttcaaaa acaactccta
     8581 agcttaaaaa aagctgatga acagattttt tgaacttaag agagattgcc atgattttct
     8641 aatcatttga tgtttaaaat gataaaaata tgaacttgaa atgaaagaat gtgagtagta
     8701 aactagaacc gtatcaaaaa taatgaaatg gagtgatttt atgaaaacaa aatcaaaacg
     8761 ctttttaaac ctagcaaccc tttgcttggc cctactagga acaactttgt taatgacaca
     8821 gccggtaaag gcggagatag taaaaagccc agaagcggaa cagactgtaa tgcagaaaaa
     8881 tggagtcact gagaccgata atagctatca gaaagaatgg gataggggtt acgatgaagg
     8941 atataaaaag gggaatgagc gtaattctcc aaaaaaacca gaacattcac ctgttgctga
     9001 tggtagtggt tatagtgatg gttatagtac aggttatgga gctggatggt acgatggtca
     9061 tttagtggaa gctattatag acggtttaat atcgtggttt aattatattt tctttggatc
     9121 aggcggttca tccgagtagt catgtctatc tagctatgct tttcggtaag taactagaaa
     9181 ataagaacgc taaagacgaa tctgaagttt tatcgtaatt ctataggtgt gactaccgta
     9241 actatacaat actgtatgag gagctatttc agaatatttt ttgatctata ttgagtgtaa
     9301 t
//
LOCUS       DAUCXI010000055         9206 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.055, whole genome shotgun sequence.
ACCESSION   DAUCXI010000055 DAUCXI010000000
VERSION     DAUCXI010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9206
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.055"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            409..891
                     /locus_tag="VGY43_001566"
     CDS             409..891
                     /locus_tag="VGY43_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEQ4302733.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTIDDVINLTVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
     gene            980..2032
                     /gene="citC"
                     /locus_tag="VGY43_001567"
     CDS             980..2032
                     /gene="citC"
                     /locus_tag="VGY43_001567"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEQ4302734.1"
                     /translation="MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDTHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQ
                     ATFPAYFQKEDNDVIKSQALLDTAIFLKIAQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWELLAKLLPKTSLDYFCSLEA
                     QPIIKKIQATSSVKHY"
     gene            complement(2142..3536)
                     /locus_tag="VGY43_001568"
     CDS             complement(2142..3536)
                     /locus_tag="VGY43_001568"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEQ4302735.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIRKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFV
                     QKSIENGIDIVRIFDALNDPRNLQTAVSATKKFGGHAQVAISYTTSPVYTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YRETGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLADKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEGIKEKII
                     GDEVVITCRPADLIEPQMIYLRDEIAPYARSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(3551..4129)
                     /gene="citX"
                     /locus_tag="VGY43_001569"
     CDS             complement(3551..4129)
                     /gene="citX"
                     /locus_tag="VGY43_001569"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEQ4302736.1"
                     /translation="MCKDTYFSGEAIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEAFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRDL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLHSFFNKDNQSSSSDKTG"
     gene            complement(4122..5654)
                     /gene="citF"
                     /locus_tag="VGY43_001570"
     CDS             complement(4122..5654)
                     /gene="citF"
                     /locus_tag="VGY43_001570"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEQ4302737.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELANIKQYDESSRRIKPVKPG
                     DSKLLGSVREAIEKTGLTDGMTISFHHHFREGDFIMNIVLEEIAKMGIKNLSIAPSSI
                     ANVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLMENPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDAYGNVNGTKGKATCGSLGYAMIDAKYAEQVVILTDNLVPYPNTPT
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITNSPYFKEGFSF
                     QTGTGGASLAVTRFMREAMIKENIKASFALGGITNAMVELLEEGLVEKILDVQDFDHP
                     SAVSLGKHAEHYEIDANMYASPLSKGAVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEVGIAINP
                     NRQDLVDHFKSLNVPQFSIEELKEKAYAIVGTPERIQYGDKVVALIEYRDGSLMDVVY
                     NV"
     gene            complement(5657..6544)
                     /gene="citE"
                     /locus_tag="VGY43_001571"
     CDS             complement(5657..6544)
                     /gene="citE"
                     /locus_tag="VGY43_001571"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEQ4302738.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGVLDIEAVVLAGVNVIRLPKTETAQDIV
                     DVEAVIERVERENGIEVGRTRMMAAIESAEGVLNAREIAKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEIDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AERVIALATAAGVLSEEDI"
     gene            complement(6532..6840)
                     /gene="citD"
                     /locus_tag="VGY43_001572"
     CDS             complement(6532..6840)
                     /gene="citD"
                     /locus_tag="VGY43_001572"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEQ4302739.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEQTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGVDQYDWKEIDSWNV
                     "
     gene            complement(7028..8149)
                     /locus_tag="VGY43_001573"
     CDS             complement(7028..8149)
                     /locus_tag="VGY43_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEQ4302740.1"
                     /translation="MDTLIAGITSITIPQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFEALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQMTKILFPIIITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            complement(8194..8589)
                     /locus_tag="VGY43_001574"
     CDS             complement(8194..8589)
                     /locus_tag="VGY43_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEQ4302741.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVSVPTEA
                     SPQVEEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VALSAGTITAIHVGPGQVVNPGDGLITIG"
     gene            complement(8646..8969)
                     /locus_tag="VGY43_001575"
     CDS             complement(8646..8969)
                     /locus_tag="VGY43_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302742.1"
                     /translation="MQFLQKWFKHSKKEKLKESSPLSTEIEPSENWEKIPAYIPADKS
                     DYKKVTLITSVIAAGDRPNSQFKVKRILKRNPEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
BASE COUNT         2733 a         1870 c         1834 g         2769 t
ORIGIN      
        1 ttttaggatt attcttgtta aaatacttaa tgttattact gataacttag agtaatataa
       61 agctaaaatt gaaggaatat tagagaatca tgaagacagc ttctttaaca tcaattggtt
      121 gaatacaagg atcagataac attatcgcta gatagtctga agaatcaaaa acaaagtttg
      181 ttacataaat aaattcttgt caaaacttgt attttctatt tgaactgata cgattgacaa
      241 aggctaaact aaaatagctt gactttttta gaatctttgt attttttgtc ggatcccctc
      301 ctattttttc cttgaattga tctatttaat cttttagaac aaggtttatc gcatactatt
      361 tttagacaat ttgttataat aaaaagaaac gacttgagga gataaaagat gccaaagaga
      421 ataagaaaag ctctaggagt agttgggaaa ctgatgtcaa ttgttcctga cactactgaa
      481 attattggaa aaacgattga taacagtcga ccaattatcg aaaaacgtat ggaacaaaaa
      541 catgaaaaag agatgcaact acgcacgata gatgatgtga ttaatcttac tgttgatcag
      601 gcacaagctc atttggaaca acttggcttt gtagtagcca ctatacctgc taagcctcat
      661 aaaaaatggc ttcatagtaa tctcaatgaa gtggttgcta tgtctccaaa atctggtaaa
      721 tataagatag gaagcctgat caaactctac tacattactg ttgatgtttt ggaaaaaagt
      781 caagacttat tagaccaaga aaacttgcgg actgtggaac gcaatcaaaa aatcgctgat
      841 acttttgagt ctgtcaaaca cattcgattt ccttttaaaa aatggcgttg ataaaaaaca
      901 gagttgcctt tagatagatc agcctgtttt ggtactaagt tatgttatga ttcaataaaa
      961 ttaaagataa ggagaagaaa tgccttacta cactatttca aaagtctttc cttcagataa
     1021 aacgacaatg gctagtgtaa agaacctgct tcatcaagaa ggtattcgtt tggatactca
     1081 tttagattat acttgtgcca tcatgaatgc gcaaaatgat gtgattgcta ccggttctta
     1141 ctttggaaat agcttgcgct gtctttgcgt atccagtgcc tatcaaggtg aaggacttct
     1201 taataggatt gtgagtcatc tcattgatga agaatatgcc cttggcaact atcatctttt
     1261 tgtttatacg aagacctctt ctgctgcttt tttcaaagat cttggtttta ctgaaattgt
     1321 ccatatcgac aatcacatca gtttcttgga aaataaaaaa actggttttc aagattatct
     1381 gatgacactt aataagcctg agcaaacacc tggtaaagtc gctgctattg ttatcaacgc
     1441 taaccccttt accttagggc atcaattttt agtagagaaa gctgcaagag aaaatgattg
     1501 ggttcatctg tttatggtca gtgaagaccg cagtctaatt cctttttcgg tgagaaagag
     1561 gttgattcaa gaaggtctag ctcatcttga taatgtcata tatcatgaaa caggtcctta
     1621 tttgattagc caagcgactt tcccagccta tttccaaaaa gaagacaatg acgtgattaa
     1681 gagccaagct ttgctggata ccgctatttt tctaaagatt gctcaaacct tacagattac
     1741 aaaaagatac gttggagaag agccaaccag ccgagtaact gctatttaca atgaaattat
     1801 ggcagagcag ttgcagcaag ctggtatcct cctagatatt ttgccaagga aagctatcaa
     1861 tcagcagcaa gatcctatca gtgcctcaac ggctaggcag gcattgaaag ataatgattg
     1921 ggaacttctg gcaaaactcc ttcccaaaac gtctttagat tatttttgtt cgctagaagc
     1981 ccaacccatt attaaaaaga tacaagccac ttcatctgtc aaacattact aagataaaaa
     2041 acctatctga ttatcaaaat caggtaggtt tttggtattg ttcttacagc aaatgcgttt
     2101 caccaaggag attaatggtt aagaggatta gtcattccct gttagtcttg aatgtccagt
     2161 tgtacagtaa cttcttgaac cggaacatca tagaaaggat cttcacggcg tcccaagaaa
     2221 tctctggctt gctgtgggaa actcgcatag cttaacacgt cttcttctga acgagcgtat
     2281 ggagcaatct cgtcacgtag ataaatcatt tgaggctcga ttaggtcggc tggtctgcaa
     2341 gtaataacta cttcgtcacc aatgattttc tctttgatac cttctgctaa tggcgctggt
     2401 gattgaccgt atagccctcg aacatagtct ttgatttcat ttggaactac cttgtagcgt
     2461 tcccctgaga tgatattcat caaggcctgt gtgccaacca tttgtgataa tggcgttaca
     2521 agtggtggat atccaagatc ggcccttact ttaggtactt ctgctaagac ttcttcgtat
     2581 ttatcagcta ggccttgctc ggttaattgg ctcaataggt ttgatagcat gccacctgga
     2641 acttggtaaa tcaatgtttt tggctcagta tctttgactt taggatttaa aatccctgtc
     2701 tctcgatagt ggtcacgaat agtgttgaaa tattctgcaa ctttggccac ctcttgcata
     2761 tccaagccag tgtcaaagcc taaatccgtc aaggcaatcg ccattgactc tgtggcaggc
     2821 tgactggttc cccctgaaaa agaggaaatc gccgtatcaa taatatcagc tcctgcttct
     2881 gctactttta agtaagtcat ttctgaaata ccactggtag catgggtatg aacctcaaga
     2941 gggatagttg tattctcctt gatacatttg accaattggt aacctatttc aggagttaag
     3001 acaccagcca tgtctttgat acaaatggag tccgctccga tagcttggta agctttcgcc
     3061 aattcaacaa agtaatcaat ggtatatacc ggacttgtcg tgtaagaaat ggcaacttga
     3121 gcatgccctc caaatttttt agtcgctgaa acagctgttt gcaagttgcg agggtcattt
     3181 aaagcatcga agatacggac aatatcaatc ccgttttcaa tggatttttg aacgaaggat
     3241 ctgaccacat cgtcagcata attgcgatat ccaagaaggt tttgtccgcg taagagcatc
     3301 tgaagtttag tctttttcac tgctttacgg atggctctta gccgttccca agggtcttca
     3361 tttaaaaagc gtaggcagga atcaaaggtt gctcctcccc acatttcaag ggcatgataa
     3421 ccagcattgt ctagcgtttc gagaatagga atcatttcct tggttgtcat acgtgtggca
     3481 atctgacttt gttgaccatc acgtaaaact gtttccgtta tacggatttt cgtcataatt
     3541 gttctcctca tcaacctgtc ttatctgatg acgatgattg gttgtcttta ttgaaaaatg
     3601 aatggagtaa ttttgaaata gcagtctgca tctcctcgac actgtgctta cgtaggcgac
     3661 cgcagacttt ggcctcttta gaacagataa aacattgcct aggggagcct cctaatacgg
     3721 ttctgctaat tgaatgaggc agatcatttt gcaagaccaa gacatctaag tccatgagac
     3781 gacctattgg caactctgtc tctaaggcta tcatttttaa cttcaggtcg cggctaggta
     3841 gacttgtgat gaggtaatac tcataacccg ttgtaggcag taatcgcaac tggtaacaaa
     3901 ttttatcgtc agctaaggca gtttgaatgg ccttaatcac tatatcaaaa gcttcaagaa
     3961 gtttaggaga ggttttaatt ggtccaggga tattcatggt gaccgataat aagctacctt
     4021 ctgggtattc ctttaataaa tgcagttgac gcagagctct ttcttcgcgg gctcttaaca
     4081 tatcactaag ttggatagct tcgcctgaaa aataagtgtc tttacacatt gtaaaccaca
     4141 tccatgaggc taccatcacg gtattcaata agagcaacaa ccttatcacc atattgaata
     4201 cgctcaggtg tgccaacgat ggcgtaagcc ttctctttta gctcctcaat actaaattgt
     4261 ggcacattga gggatttgaa atggtctact aagtcttgac gatttgggtt aatggcaatt
     4321 cccacttctg tgacgaccac atcgacactt gttcctggtg taatgaccgt attaacctca
     4381 tctacaaaag ttgggatgcg tccgcggata agtggtgaaa taaccaaact catcttagcc
     4441 gcaaaggcag tgtcgcagtg tcctccagaa gcgccacgaa tcacgccgtc agatcctgtc
     4501 atcacattaa cattgaagtt agtatcaact tcaagggctg ataaaataca agtgtctaat
     4561 tgattgataa cagcaccctt gctcaaaggt gaggcataca tgttggcatc aatttcataa
     4621 tgttcagcat gcttaccaag agaaacagct gatgggtgat caaagtcttg gacatcaaga
     4681 attttttcaa ccagtccttc ttcgagcaac tccaccatag cattggtaat accaccaaga
     4741 gcaaagctag ctttgatatt ttctttaatc atagcttcac gcatgaaacg ggttactgcc
     4801 aaagaagcgc cacctgttcc agtttggaaa gagaatcctt ctttaaaata aggagagttg
     4861 gtgattactt tagcggcgta ttctgcaatt aagagttctt taggattttt cgtaaaacga
     4921 gttgcccctt tggcgattcc ttgaggatct ccgatagcat ccactgttac cacatagtca
     4981 acatctgttt gaggaatgct ggttggggta ttaggataag gaaccaaatt atctgtcaag
     5041 ataaccacct gttccgcata tttggcatca atcatggcat agcccaaaga accacaggtt
     5101 gctttccctt ttgtcccatt aacatttccg taagcatctg aacttggggc gcccagaaag
     5161 gcaacatcaa tatggatatc cccactagca atggcacgag cgcgaccacc atgggagcga
     5221 ataaccacag gattttccat tagtccttct gaaatggctg cccctacttt gtcacgaaga
     5281 ccagatgaag tgatgttagt gaccacacca tttttgatgt gatcaatcaa aggctcatgt
     5341 acattagcga tggaacttgg ggcaatagac aggtttttaa tgcccatttt ggcaatttcc
     5401 tccaagacta tattcataat gaaatcccct tcacggaaat ggtggtggaa agaaatggtc
     5461 atgccatctg ttaaacctgt tttttcaatc gcttcacgaa cagatcctag taatttagaa
     5521 tctccaggct taactggttt aatacggcga cttgattcgt catactgttt gatatttgcg
     5581 agttctcctt caaagacacc gtattggtcg gcgtatggtt gaggaatatc tctaccgagt
     5641 ttatttgtta ccatctttaa atgtcctcct cagataaaac acctgctgct gttgctaggg
     5701 caatgacacg ttctgcacgt tcaacgattg gtttatcaac catttttcca tttaaggaaa
     5761 taacgccaga gcctttgctt tcagcttcac gaattgccca gatgacttgt ttggcatggt
     5821 caatttcttt ttcggttggg gtataaatct cattgaccag aggaatttga cgagggttga
     5881 tgaccgattt accgtcaaat cctaactgtt tgatcatacg aacttcgttt tggaatcctt
     5941 ctgtattatt gacatcagaa taaacagtat caatggcagc aattccagca gcacgagcag
     6001 catgtaaaat catgctacga gcaaagaata attcttgacc atctgggtaa cgacgcgttt
     6061 tcatattcgt gacatagtct tctgccccaa gagcaatacc aatcaagcgc ttagaagctt
     6121 tggcaatctc acgagcattt aggacacctt cggctgattc aatggctgcc atcatgcgtg
     6181 tgcgaccaac ttcaatgccg ttttcgcgtt cgacacgttc aataacagcc tccacatcaa
     6241 caatatcttg ggcagtctct gtttttggaa gacgaatcac gttgacacct gccaaaacaa
     6301 cagcttcgat gtctaaaacc ccacaagaat caagaccatt cacacgaaca accgtttcaa
     6361 cgcttgaata atcaaaagtt ttaagcgcaa aatgaacgag agctctagag gtgtcttttt
     6421 ctttgagtga aacagaatct tccaagtcaa acatgattga atcagcgcca aataaaggag
     6481 catctcgaag catggctgca ttggcacctg gcacaaacat cattgttctt cttaaacgtt
     6541 ccatgagtca atctccttcc aatcgtattg gtcaacacca gctgcgcgat gaacagctgc
     6601 gatggttctc gcttgaatgg tgcaatctaa agcgccttta tcaacagcct ctactttagc
     6661 agccgtcacc ttcaaattca ctagggtttg atgaatgagt tgacgaatgt gattgccaaa
     6721 ttgtttttca acactactgt ctagggttat tgtaatggtt tgctcgtcat taggggatac
     6781 tgtaatcatt aggtcacttg attcaagtga accagcaacg gcagtttgtt taatatccat
     6841 tgcgtttacc tccttgattt tcttaaatga tattgttatt tactaactgg gaaaagtttg
     6901 atcaggatct ctgcgacaag atagagaatg cctaacacga taaagacacc tgccatacca
     6961 agcgccatta gctcaaagga actaatcaaa tggtccatat taattgtcat aaggtttcct
     7021 tcctttctta gctaaagtaa gctagcaaca aaccacctgc gataacagag gcgatttggc
     7081 cagagacatt ggcacctaca gcgtacatga ggataaagtt ttgcgggtct tcatctgttg
     7141 ccattttttg aatgacacga cttgacattg gaaaagctga aatacccgca gcgccaatca
     7201 ttggattaat cttctctttt cggaagagat tgagaaattt ggcaaacatg accccaccga
     7261 tagaatccat gataaaagca agtaaaccaa agacgatgat taagagtgtc tgtacattta
     7321 agaacaggtc tgcctgcatt ttaatagaga tggtcaatcc aagcaagata ctaataatgt
     7381 ttaccaattc attttgagca gtttgtgaca ggcgatcgag cacaccacac tcacgtaata
     7441 agttaccgaa catcaaaaag ccaactaaag gtagagaaat tggggcgatg aaccctgcta
     7501 ctaaggtaat gatgattggg aataagattt tagtcatttg agatacattc tcagctttgt
     7561 aagtcatacg gatacggcgc tcttttttcg ttgtcactaa tttaatggca aatggttgga
     7621 taataggaac cagagccatg taagaatagg ctgcaaccgt aattggaccc agtaaatcct
     7681 tggccagttg gttggcaaca aagatagaag tcggtccgtc tgctgctccg ataatgccga
     7741 ttgaagctgc ttctttaatg tcaaagccag ccagtacggc aacaacgaca acaaagaaaa
     7801 ttccgaattg agctgcagca ccaaacaaga gcatgaatgg gttttgaagc aagggaccaa
     7861 agtcaatcat ggctcctata ccaatgaaaa tcaacagtgg gaaaagttct gttccaatcc
     7921 caaaattgaa gagagcctca aaaacccctt cttgctcgac tccgttaacc acttgggtta
     7981 aaactcctga accagggaag ttaacgagaa tggttccaag tcccatgggg acaagtaagg
     8041 ttggttcgta ttctttttta attcctagat acattaagag ggcaccgatg accatcataa
     8101 caatttgagg aatggtgatg gaggttattc ctgcgattaa agtgtccaca aattcacttc
     8161 cttttctgtc tatttattct agttatagta ctattaacca attgtaatga gaccatcacc
     8221 aggattgacc acttgacctg gaccgacgtg gatagctgta atggttcctg ctgataaggc
     8281 cacaatctca ttttccatct tcatggcttc taaaatcaat agtggctgat tttcagttac
     8341 ttggtctccc actgctacta agacttttaa gatggttcca ggcattggtg atggaatggc
     8401 atccgctccc gctgcagcta ctggctgtgg tgcttgcgct tcctccactt gtgggcttgc
     8461 ttcagtaggg acagatactg gagtggatat tggttgagcg ggggcagctg cttgggcagg
     8521 agcaccgatt tcttccattt ctacaagata ttctttaccg tcaatggtaa ttttaaattt
     8581 tcgtaacatc atttttctcc tatatgttat tgtgtcatga gttcgtctaa agtatcgttc
     8641 accgactacc ttttgcaata gatggatgtc acccgaaact gactttctgg gtaaacacct
     8701 gcagcgatac ttgaagcaat taaagaaaca gtgattgcct caggattgcg cttgagaatg
     8761 cgtttaacct tgaattgact attaggtcta tcgccagcag caataacact ggtaattaaa
     8821 gtaacctttt tgtaatcact tttgtctgca ggaatataag cgggaatctt ttcccagttt
     8881 tcagaaggtt ctatttctgt actaaggggc gaggattctt tcaacttctc ttttttagag
     8941 tgtttaaacc atttttgtaa aaactgcatg agctacctct ttttcacatt tacctattta
     9001 gggaactagt aagtttatta tatactacca atcttttttg agatggcttt tttgtgttct
     9061 ttctaagagc gctttcaatg tttcataaag cttttcaaca gttacctaaa aacaaaataa
     9121 aaggtaactg ttgaaaagct gagatcaaga tactgatagc aagaaaagct tgatctaact
     9181 aggttcatca ttattataga aaattt
//
LOCUS       DAUCXI010000056         8981 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.056, whole genome shotgun sequence.
ACCESSION   DAUCXI010000056 DAUCXI010000000
VERSION     DAUCXI010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8981
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.056"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(88..1401)
                     /locus_tag="VGY43_001576"
     CDS             complement(88..1401)
                     /locus_tag="VGY43_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEQ4302743.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVALT
                     SLWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIWSVLAGLILSLFAHAYKHLLEHLPK
                     ADARSQWFIPKVLIAFSLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVTKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
     gene            complement(1376..2335)
                     /gene="nrdF"
                     /locus_tag="VGY43_001577"
     CDS             complement(1376..2335)
                     /gene="nrdF"
                     /locus_tag="VGY43_001577"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEQ4302744.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            complement(2539..4698)
                     /gene="nrdE"
                     /locus_tag="VGY43_001578"
     CDS             complement(2539..4698)
                     /gene="nrdE"
                     /locus_tag="VGY43_001578"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEQ4302745.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYHPEFITELASIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSNIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYADGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQASDWEALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(4718..4936)
                     /locus_tag="VGY43_001579"
     CDS             complement(4718..4936)
                     /locus_tag="VGY43_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HEQ4302746.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            5329..5592
                     /locus_tag="VGY43_001580"
     CDS             5329..5592
                     /locus_tag="VGY43_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEQ4302747.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            5597..7330
                     /gene="ptsP"
                     /locus_tag="VGY43_001581"
     CDS             5597..7330
                     /gene="ptsP"
                     /locus_tag="VGY43_001581"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEQ4302748.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWVGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            7515..8942
                     /locus_tag="VGY43_001582"
     CDS             7515..8942
                     /locus_tag="VGY43_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEQ4302749.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRALSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALISGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLVLAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEADADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
BASE COUNT         2858 a         1623 c         1876 g         2624 t
ORIGIN      
        1 ttcctcgttt ccacttaatt ttgtgtctac tttagtatac caagtccaat tcatccgaag
       61 ctttttatta aaaaagtaat taactaatca tttaaggatg aaacgataaa actgatagct
      121 aaaataaaaa atgaggttag ctaatgctaa agggataatc attagtaacg attggcctgt
      181 aatttcaacc agaaaaactg gtgccgccaa gggtatctta ttgatcacac ctaaaaagat
      241 tgttgcacca accataatgg ctaacgtatt tgatagagac aagggaataa ggtactgact
      301 aaggatagct agtagtaagc cactagcacc tccaagcatc atagaaggag caattttacc
      361 cccttttgct ccagaagcaa aaactaaaga gatagcgaca gctttggtaa caagtagcca
      421 gctaatatag ctcagatgtg gttcttcatg gagaaaaaag agtaatccag ctttgccatt
      481 tcctaaaatc tctgggaaga aaatgctgag tcctgcgata aggctaaaag cgatgagaac
      541 tttcggaata aaccactgac ttctggcatc agccttagga aggtgttcca aaagatgttt
      601 gtaagcgtga gcaaagaggg aaaggataag accagccagg acggaccaaa taagggttcc
      661 tagcgtccaa tgttgctgag gcattaggta ttgaatctca tgtcgtcctt gtaataaagc
      721 aactgtttcc acagccacat agctcgttag gcaggcagcg tatatatttt taagggacca
      781 acggttaaga atagcttcca agataaataa aatagtggct aagggagcat tgtagacagc
      841 accaagggca gcgccagaag cgcaagctaa taaaagtttt tgatcggctt ttgacaagtt
      901 acatctttgg ctccaaagag acgtcaaggc aacagcgact tcccgtgaag ctccttctcg
      961 gccgacagga gctcccatag atacggtcgt taattggagc caaccatgcc aaaactgtgt
     1021 ccagggacta aatgagatgt catcttgaat gatttgctga atagattgaa tgtcctttcc
     1081 ttttttagcc aataggtgcc acccaagacc tgcaagaagt ccagcaaaga ggagtgaaag
     1141 agctcgtctt tgtggtggaa cactagcaat catagtgcta aaagaacctt gactgaatcc
     1201 aaaactgagg gactgaatca ggtgaatggc ttttgttaag ataaaagcaa caaggccagc
     1261 tgttaaacct gttaaaaaga ggtaaaaggt caagagtaaa aagtgtcgtt tcataagact
     1321 attataacaa aagttaagaa aagagactga taaattatca gtctcgtgag cactattaga
     1381 gtccataatt ataatcgtca tcagacatag cttctacaga accaagaaga tagccattcc
     1441 ctacctgtga gaaaaagtca tggtttgatg ttcctgttga aataccattc ataacaattg
     1501 ggttaacatc gtttgctgta tctgggaata aaggatcctg tcctaaattc ataagagctt
     1561 tgttagcatt gtagcgtaaa aaggtcataa cttcttcagt ccaccctacg ccatcataaa
     1621 gcgttttggt gtatttttct tcattttcat acagctgata aaggaggtca tacatccaat
     1681 cacgaaaatt ctcttgctca tcttctggta gttcgttaaa accaagctgg aatttgtaac
     1741 cgatataagt accatgtaca gattcatcac gaataattag tttaatgatt tcagcaacat
     1801 ttgctagctt attatttccc aaatagtaaa gaggggtgaa aaagccagaa taaaaaagga
     1861 aagtttcgag atatgttgaa gcaactttct tttgtaaggc atctccatta gcgtaaatgt
     1921 cattgataat acgtgctttt tcttgaagaa actcattatt attagtccac tcaaagatct
     1981 cttcaatttc tttttttgtg tttaaggttg aaaagataga cgaataagat ttagcgtgaa
     2041 ctgattccat gaattgaata ttgtttaaga cagcttcttc gtgaggagtg cgaacatcag
     2101 cacgaatagc ttcgacacca gtttctgatt gcatggtatc aagtagggtt aatcctccaa
     2161 aaaccttgcc aacaagatct ttttcttgaa gagaaagttt gcgccaatcg tctaagtcat
     2221 ttgataaagg gatacgggta tcaagccaaa attgttcggt caacttttcc caagttgact
     2281 tgtcaatgac gtcttcgatt tcattccagt taattgcttc ataatatgta gtcatagaaa
     2341 aatgatctcc taaagagtag taaagtgcgt taaggatatc gagataaacc agtagaaccg
     2401 accaaagttc taccggtaat aataagttta aatagattca aaagggtaac gaatgagtta
     2461 gtgagtggtt taggcagatc gcctaaagcg actgccgtag aagtaataga tgctttagca
     2521 tcattacttc ttaaccaatt aaatgacaca agattcacat tggtttgcgc ccacttcttc
     2581 cccatcatcc gtaaaggtac ggatatagta gatagattta atgcctttat tgaaagcgta
     2641 gtttcgtaag atggataaat cacgagtggt ttgtttgctt tgtgttttcc actcataaag
     2701 ctccataggc aactcactac gaaggaatag agttaatgac aagccttggt ccacatgttc
     2761 ggtcgcagcg gcatagacat caataacttt gcgcatgtcc atatcgtaag cagatgtata
     2821 gtaaggaatg gtatccgtag acaaaccatt tgcaggatag tagattttac caattttctt
     2881 ttcttgacgc tcttcgatgc gttgtgtgat tgggtgaata gaagcagagc agtcattgat
     2941 ataagaaata gagccatttg gagcaactgc tagtcggttt tgatgataaa gaccatcttt
     3001 ttgaacggcg tcgcgaagag cctcccaatc tgaagcttgc ggaataaaat ggtctttaaa
     3061 gagacttttg accaaatcag attttggaac aaagtgtcct gtaacgtatt tatcaaagta
     3121 actaccatca gcgtacttag agttctcaaa gccaacaaag gtagtttggc gctcacgagc
     3181 gatgttattg gattcgacca aggtccaata attcaggagc ataaagtaaa tatcagtaaa
     3241 ctcgatggat tctggactgc catattcaat atgatgttga gcaaggtaag aatgtagtcc
     3301 catagctcca agaccaaaag tatgtgcttg actgttacca tgtttaatgg ttgggacagc
     3361 ttcgatgttt gatgagtcgg tcacgaaggt taaggcacgt gtcatggtct taatagaacg
     3421 gccaaagtct ggtgaggtca tcatgttcag gatattagtg gaacctaagt tacatgaaat
     3481 atcagttccc atttctacaa actcttgcgc atcattgata aggctaggtg tttgaacttg
     3541 taaaatttca gaacacaagt tgctcatgat gatttttcca tcgataggat tagctttatt
     3601 agctgtatca atattgatga tataagggta accagattct tgttgtaatt ttgaaatctc
     3661 tgtttcaaga tcacgagctt taattttagt cttagtaatt ttagggttcg ccactaactc
     3721 atcgtacata ttggtaatgt cgagatagtt aaagggaatg ccatattctt tttcaacatt
     3781 gtaaggacta aagagataca tgtcctcgtt tttacgagct aattcgtaga atttatcagg
     3841 aacggtaatc cctagtgaca aggttttaac acgcaccttt tcatcggcat tttctttttt
     3901 agtagataag aaagcaatga tatcaggatg aaaaacattt aggtaaacaa caccagctcc
     3961 ttgacgttgc ccaagttgat ttgaataaga aaaactatct tcaaataatt tcataacagg
     4021 aacaactcct gaggctgcac cagcatagcc tttgattggt gcgccagctt cacggaggtt
     4081 agacaaggta atcccaacac ctccaccaat acgggataat tgcaaagcag agttgataga
     4141 acgtccgata gagttcatgt catcagttac ttgaatcaag aaacaagaga ccaattcacc
     4201 acgacggctt cgaccagcat ttaaaaagga aggagtagcc ggttggtaac gttggttaat
     4261 catttcaacg gctaaatctt ttgctaagtc ttcttgacca tctgcaaaat acaaagcatt
     4321 aaacaagaca cggtcttcaa ggttttctaa ataatgctct ccatcatttg tttttaaggc
     4381 gtattgctgg tagaacttgt aggctgccat aaatgattta aagcgaaaat tttctgattt
     4441 gattatgcta gctaattcag taataaattc agggtggtat ttctgaataa aagctgattc
     4501 aatgtaatca tttgagatta aatactcaat tttttccgta atggaagtaa aagacatggt
     4561 gtttggcagc acattttcag cgaaaaaagc ttttaaagct tctttgtctt tatgaagtgg
     4621 aattttacca ttaacaggac gattaatttc attatttagg cgaaaatatg aaatatcgcc
     4681 aagatctttg agactcatat tatttttcct tgtcttatta aatcaattct tttaactttg
     4741 caggttggaa gccagaaaat acgaggttat ctgcttcgat aacaggagca gatgtgaagc
     4801 caagactttt cacataatcc actttttcag gatgttcatc gatattaatt tcctggaagt
     4861 tggctccgtg ttgttctaaa aatttcttag tcattttgca ctgcatgcaa ttatttttgg
     4921 aatatactgt aatcatgtct tgtccttcta aaattagtaa tggttccatc ttaaatggaa
     4981 ttactataat agcatataaa aaataaagct aaaaagcaag ctataaactt atctgaaaca
     5041 caacatattg tgttgaaata aaaaacagaa acctaaatat tgtgtcaatc tggattctta
     5101 tggttagagc tctagcgttt tggtgataga agctaagcag ttttaataaa gcattaaagt
     5161 ctgaaaaata aattgtgaaa aacgtgaaaa taaaagaaaa taatttcaca ttttttgtcg
     5221 tttaaatatt taatcttgaa aataaaaaag cattgtgcta taatcggttg ttgtaagggt
     5281 tatcatgtga tggctcaaaa atacacaact taaaaggaga accatactat ggcttcaaaa
     5341 gactttcaca ttgttgcaga aacaggtatt catgcgcgtc cagcgacttt gcttgttcaa
     5401 acagctagca aatttgcttc agacatcact cttgactaca aaggtaaagc agtaaatcta
     5461 aaatcaatca tgggtgttat gagtcttggt gttggtcaag gtgcagatgt tactatctca
     5521 gctgaaggtg cagatgctga agatgccatt gcagcaattg aagaaacaat gactaaagag
     5581 ggattggcat aagactatga cagaaatgct taaaggaatt gcagcctcag acggcgttgc
     5641 tgttgctaaa gcatatctac tagttcagcc ggatttgtca tttgagactg ttacagtcgc
     5701 agatacaaat gcagaagaag ctcgccttga tgttgcactc caagctgcac aagacgagct
     5761 ttctgttatc cgtgaaaatg cagtagaaag cttaggtgaa gaagcagcag ccgtttttga
     5821 tgcccattta atggttcttg ctgatccaga aatgatcagc caggttaaag aaacgattcg
     5881 cgcaaaacaa acgaatgcag aaacaggtct taaagaagtg actgacatgt tcatcaccat
     5941 ctttgaaggc atggaagata acccatacat gcaagaacgt gcagcggaca tccgcgacgt
     6001 tgcaaagcgt gtgttggctc accttttagg tgtaaaactt ccaaatccag ctacaatcaa
     6061 tgaagaatca atcgttatcg cacacgattt gacaccttca gatactgctc aacttaacaa
     6121 acaatttgta aaagcatttg ttacaaatat cggtggtcgt acaagtcact cagctatcat
     6181 ggcacgtaca cttgagatcg ctgcggtact tggaacaaat gatattacaa aacgtgttaa
     6241 agatggtgat gtgattgccg ttaatggtat cactggtgaa gtgattatcg atccaagcga
     6301 agatcaagta cttgctttta aagaagctgg tgcggcttat gccaaacaaa aagcagagtg
     6361 gtctctcctt aaagatgcgc atactgagac agctgatggc aaacactttg aattggctgc
     6421 taatatcggt acgcctaaag acgttgaagg tgttaatgac aatggcgctg aagctgttgg
     6481 cctttaccgt actgagttct tgtacatgga ttctcaagac ttcccaactg aagacgaaca
     6541 atacgaagct tacaaggcag tgcttgaagg catgaatggc aaacctgttg tggttcgtac
     6601 gatggatatt ggtggcgaca aggaacttcc ttactttgac cttccaaaag aaatgaaccc
     6661 attcctcggt ttccgtgctc ttcgtatctc aatctctgaa actggggatg ccatgttccg
     6721 cacacaaatg cgtgcgcttc ttcgcgcctc tgttcacgga caacttcgta tcatgttccc
     6781 aatggtagca cttcttaaag aattccgtgc tgcaaaagca gtctttgacg aagaaaaagc
     6841 aaacttgctt gcagaaggcg ttgcggttgc tgatgacatc caagttggta tcatgattga
     6901 gattcctgca gctgctatgc ttgcagacca atttgctaag gaagttgatt tcttctcaat
     6961 tggaacaaac gaccttatcc aatacactat ggcagcagac cgtatgaacg aacaagtatc
     7021 atacctttac caaccataca acccatcaat attacgtttg atcaacaatg tgatcaaagc
     7081 agcgcacgct gaaggtaaat gggtaggtat gtgtggtgag atggcaggtg accaacaagc
     7141 tgttccactt cttgttggaa tgggcttgga tgagttttct atgtcagcaa cttcagtact
     7201 tcgtacgcgt agtttaatga agaaacttga ctctgctaag atggaagaat atgcaaatcg
     7261 tgcgcttaca gaatgttcaa cagcagaaga agttcttgaa ctttctaaag aatacgtttc
     7321 tgaagattaa cgggttaaag agttggttta aaccagctct tttttgctag ctaaaaatac
     7381 aattactttt tggtgtgaaa tcatttgagt tatcaaataa ttatcagaat tttcagatat
     7441 ttagtgtagc caaatcttga attatatcgg aaaagtgata gaataaaatt actatcataa
     7501 aaggagataa aacgttggca aaacaatata aaaatttagt gaacggtgaa tggaaactat
     7561 cagaaaacga gattaccatt tacgcaccag caacaggtga agagttagga tcagttccag
     7621 cgatgacgca ggcagaggta gatgctgttt acgcttcagc taaaaaggct ctatcagatt
     7681 ggcgcgcctt gtcttatgtg gaacgtgcag cttaccttca taaagcggct gatattttag
     7741 tacgtgatgc tgaaaagatc ggcgcgattc tttcaaaaga agtagccaaa ggtcacaagg
     7801 cagctgtcag tgaagttatt cgtaccgctg aaatcattaa ttatgcagca gaagaagggc
     7861 ttcgtatgga aggtgaagtt cttgaaggtg gtagcttcga agccgcaagt aagaagaaga
     7921 ttgctattgt tcgtcgtgaa ccagttggtt tagttcttgc catctcacct tttaattatc
     7981 ccgttaactt ggcaggttct aaaattgctc cagcccttat ttcaggaaat gttgttgctc
     8041 ttaaaccacc aacacaaggc tctatttctg gtttgttact agcagaagct tttgcagaag
     8101 ctggtattcc agcaggtgtc tttaatacca ttacagggcg aggttctgtt attggggatt
     8161 acatcgttga gcatgaagcg gttaacttta tcaactttac aggttctact ccaattgggg
     8221 aaggaatcgg taaattagcg ggtatgcgac caattatgct tgagcttggc ggtaaggatt
     8281 ctgctatcgt tttggaagat gcagatcttg ttttagcagc gaaaaatatt gtagccggtg
     8341 cttttggtta ctcaggacaa cgttgtacag cggttaaacg cgttcttgtg atggacaagg
     8401 tggcggatca attggcggct gagattaaaa cacttgttga aaaactaagt gtcggaatgc
     8461 ctgaagccga tgctgatatt acaccattaa ttgatacatc agctgctgat tttgttgaag
     8521 ggttgattaa agatgcaact gataagggag ctactgcttt gacagccttt aatcgtgaag
     8581 gcaatcttat ttcacccgtt ctctttgatc atgtgacaac tgacatgcgt ttggcatggg
     8641 aagagccgtt cggcccagta ttaccaatta ttcgtgtaac cactgtagaa gaagccatca
     8701 agatttctaa tgagtctgaa tatggtttgc aagcttctat ttttacaact aatttcccaa
     8761 aagcttttgg cattgctgag caattagaag ttggaactgt tcaccttaac aataaaacac
     8821 aacgtggaac agataatttc ccattcttag gcgctaaaaa atcaggtgca ggggtacaag
     8881 gagttaaata ttctatcgaa gctatgacaa ctgttaaatc tgttgtattt gatatccagt
     8941 aataaaaaaa ataaacaaaa agttaggtta acttaacttt t
//
LOCUS       DAUCXI010000057         8813 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.057, whole genome shotgun sequence.
ACCESSION   DAUCXI010000057 DAUCXI010000000
VERSION     DAUCXI010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8813
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.057"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            83..1009
                     /locus_tag="VGY43_001583"
     CDS             83..1009
                     /locus_tag="VGY43_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEQ4302750.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLIKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKIAAFLKKVEK"
     gene            1063..1148
                     /locus_tag="VGY43_001584"
     tRNA            1063..1148
                     /locus_tag="VGY43_001584"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1097..1099,aa:Leu,seq:aag)
     gene            1354..2235
                     /locus_tag="VGY43_001585"
     CDS             1354..2235
                     /locus_tag="VGY43_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEQ4302751.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            2617..2805
                     /locus_tag="VGY43_001586"
     CDS             2617..2805
                     /locus_tag="VGY43_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEQ4302752.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            2957..3322
                     /locus_tag="VGY43_001587"
     CDS             2957..3322
                     /locus_tag="VGY43_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEQ4302753.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            3322..4986
                     /locus_tag="VGY43_001588"
     CDS             3322..4986
                     /locus_tag="VGY43_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEQ4302754.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKA
                     EVKDFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            5223..6113
                     /locus_tag="VGY43_001589"
     CDS             5223..6113
                     /locus_tag="VGY43_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEQ4302755.1"
                     /translation="MLGPFIFIAFGVIVILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHVRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNIATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            6343..7197
                     /locus_tag="VGY43_001590"
     CDS             6343..7197
                     /locus_tag="VGY43_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEQ4302756.1"
                     /translation="MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNRKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQKEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            7390..8586
                     /locus_tag="VGY43_001591"
     CDS             7390..8586
                     /locus_tag="VGY43_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEQ4302757.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALAGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
BASE COUNT         2875 a         1492 c         1876 g         2570 t
ORIGIN      
        1 aaaatagcat tagaaaaaga aaaacgtgat atttttaggt tagcactttc tttttcagtc
       61 atttttttgt aaaatacttg gtatgaaaac tattcgaata gcaaagtatt taggaattct
      121 attccttttg ataactctta ttagcgtagg tgctagtttt tatttctttc atgttgcaca
      181 aataagagaa gagaaatcgt ttattaataa taagaaacgg agtacgaata atccattata
      241 cccagctgaa cagtcttttg acgctttacc ttacgaaaaa cgtcaactaa caaatcgtgg
      301 gttaaaacaa gtggggtggt acttaccagc tgctcaaaaa acaaaaaaga cagctattgt
      361 tgttcatggt tttacgaatg acaaagaaga tatgaagcca tatgccatgc tttttcatga
      421 tttgggctat aatgtcttaa tgccagacaa tgaggcccat ggggaaagtg aagggaactt
      481 gattggttat ggctggaatg accgccttaa tgtcatggct tggacagacc aactgattaa
      541 ggaaaaccct gaaagccaaa tcacactctt tggcttatct atgggtgctg caacagtaat
      601 gatggcaagt ggtgagcgat tgcctgcgca agtcacctcc ctcatcgaag attgcggtta
      661 taccagtgtt tgggacgaat tgaagtttca ggccaaggct atgtacaact tgcctgcctt
      721 tcctttactc tatgaagtct ctgccttatc taagattcga gcaggtttta gttacggaga
      781 agcgagctca gtgaaacagc tggctaaaaa taaacgtcca actttattta tccacggtga
      841 taaggatgat tttgttccta caaaaatggt ttatgacaat tataaggcca cgaaaggtcc
      901 taaggaaatc ttgattgtta aaggggcaaa acacgccaaa tcctttgaaa caaacccaga
      961 acaataccag aaaaaaattg ccgctttttt gaaaaaagtt gagaaataag tattgacagt
     1021 taaactcaca gttgctataa taatttatgt tactgatgag tagcggggat ggcggaattg
     1081 gcagacgcgc aggactaagg atcctgtgac cgctttaggt cgtgtgggtt caagtcccac
     1141 tctccgcata atgtaagagg tgaatcattg attcgtctct ttttttggtt aaatgaagga
     1201 taagaaggca tagatttact ggagaaaact tttgataatc tgcttttgga aaacgcttta
     1261 agcttgtgaa agactagaaa tttatggaaa attgtgctag aatgaacaat gtaaacgggg
     1321 agttatcccg aaaaataaga ggaggcctta caaatggcaa tcgtttcagc agaaaaattt
     1381 gtccaagcag ctcgtgaaaa cggatatgct gttggtggat ttaacacaaa caacttagag
     1441 tggactcaag caatcttgcg tgcagcagaa gctaaacaag ctccagttct tatccaaaca
     1501 tcaatgggtg cagcaaaata catgggtggt tataaagtat gtcaatctct tattactaac
     1561 cttgttgagt caatgggtat cactgttcct gttgctatcc accttgatca tggtcactac
     1621 gaagatgctc ttgagtgtat cgaagtaggt tacacttcaa tcatgtttga cggttcacac
     1681 cttccagttg aagaaaacct tgctaaaact gcagaagttg ttaaaattgc acatgctaaa
     1741 ggcgtttcag ttgaagctga agttggtaca atcggtggtg aagaagacgg tatcatcggt
     1801 aaaggtgagc tcgctccaat cgaagatgct aaagcaatgg ttgaaactgg aattgacttc
     1861 ttggcagctg gtatcggtaa catccacggt ccatacccag aaaactggga aggtcttgct
     1921 cttgaccact tagaaaaatt aacagcagct gtaccaggtt tcccaatcgt attgcacggt
     1981 ggttctggta ttcctgacga tcaaatcaaa gaagcaatcc gtcttggtgt tgctaaagtt
     2041 aacgttaaca ctgaaagtca aatcgctttc tctaacgcaa ctcgtgaatt tgctcgtaac
     2101 tacgaagcta acgaagcaga atatgatggt aaaaaattat ttgacccacg taaattcttg
     2161 gctccaggta tgaaagctgt tcaaggtgct gttgaagaac gtatcgatgt tttcggatca
     2221 gctaacaaag cataatttag agtattaaat accctaaagc cctcttgagg gcttttttag
     2281 atacaattga caccctaaaa tggataccag tttctgtgaa acaatctttg attgtgaaca
     2341 aacaaagcat aatttagagt attaaaatct ggaccctgct atctatggta agtctttttg
     2401 ttattgttaa agaggttaag cggaatgtta atatgtttta gctaaaaaat gtagtgaaaa
     2461 atgagtacgt agactattgt aatagtaatt ccgtaaaatt gttgaaaaag aaaatgggaa
     2521 ataccttgtc aaattaagca ccctatgata gaatagatag gtatgtggtg ctagcacatc
     2581 cgtaaacata ttctacgtag gaggaaacag atcaaaatgg ctaaagtatg ttattttaca
     2641 ggacgtaaaa ccgtttctgg aaacaaccgt tcacacgcga tgaaccaaac gaaacgtaca
     2701 gttaaaccaa accttcaaaa agttactatc cttgttgatg gtaaacctaa aaaagtttgg
     2761 gcttctgctc gtgcgcttaa atctggtaaa gtagaacgca tctaatagaa ataagcctta
     2821 gggctttttt tattagctta tttctatcca taagctagtc agggtaataa acgctattgt
     2881 taactattct atctctttta cattacttct aaaatatgat aaaataggat gataaaaact
     2941 ttttgaggta gtaactatga ctgtaaaaat taatacaaaa gatggtctaa tcgagctatc
     3001 cgacgatgtg attgcaactg tcgtgggagg atcagcaacg gaaatttttg gtgttgttgg
     3061 aatggccagc aaaagtgcaa taaaagacaa ttttcaatca ctacttcgca aagaaaacta
     3121 cgctaagggt gttgtagtaa aatcaacaga tctgggtatt tctgttgatg tctacactgt
     3181 gatgagttat ggtgtgaaaa tcagtgaagt ctctaaaaat atccaagaac gcgtgaaatt
     3241 taaccttgaa agtcagcttg gtctcactgc tgatatggtc aatgtttacg tacaaaatat
     3301 taaggttgta ggagaaaatt agtgtcaaat attacaacaa gcttattcca agaaatggtc
     3361 caagcggcag cgactcgcct tggcaaacaa gcagaatatg ttaattcctt aaatgttttt
     3421 cctgttccag atggtgatac aggaacaaac atgagcatga ctatggacaa tggtgccaag
     3481 gaagttgctg ataaacctgc gtcaactgtg ggagaagttg gacaaatgtt atcaaaaggt
     3541 cttttgatgg gagcgcgtgg aaattctgga gttattactt cacaactttt tcgtggtttt
     3601 ggtcaaagca ttaaaggaaa agatgagctg acaggtaaag atttggcaca agcctttcaa
     3661 gtgggtgtag aagttgccta caaagcagtg atgaaacctg ttgaaggaac aattttaact
     3721 gtttctcggg gtgcagcgac tgctgcctta aaaaaagcag atcttacaga cgacgccgtg
     3781 gaagtcatgc aagctgcttt agacggtgcc aaaggtgccc ttgctaagac acctgattta
     3841 ttaccagtcc ttaaagaagt tggtgtggtt gattcaggcg gtcaaggtct tgtctttatc
     3901 tatgaaggtt tcctatctgc tttgaatggc gactatgtga cttcagcaga ctttaaagcg
     3961 actcctgcta acatgtctga aatgattaat gctgagcatc acaaatccgt tgttggtcat
     4021 gtggctactg aagacattac ctacggttat tgtactgaaa tcatggttgc ccttaaacaa
     4081 ggcccaacct atgtgaaaga attcaactat gatgagtttc aaggctacct tagtggcctt
     4141 ggtgactcgc tgttagtggt caatgatgat gagattgtta aagttcacgt ccatactgaa
     4201 gaccccggac ttgtgatgca agaaggtctt aaatatggtt cgctcatcaa gattaaagtg
     4261 gacaatatgc gtaaccagca tgaagcacag gttcaaaaga ctgatgtcga aaaaaacaag
     4321 gctgaagtaa aagactttgg cttgattgca gtagtagctg gagaaggttt atctgaaatt
     4381 ttcaaggcgc aaggtgttga ttacgtgatt tctggtggtc aaaccatgaa tccatctaca
     4441 gaagatattg ttaaagctat tgaagcagtt aatgccaaac aagtcattat cttgccaaac
     4501 aataaaaata tctttatggc tgcccaatct gctgcagaag tggtggatat tccggctgct
     4561 gttgttgcaa cacgtactgt tccgcaagga tttaccagct tgttggcctt tgatccttca
     4621 aaatctttag aggacaatgt agcagatatg tcaactagtc tttctgacgt ggtcagtgga
     4681 agtgttactt tggcagtccg tgacaccacc attgatggtt tagaaatcca tgaaaatgat
     4741 ttcttgggaa tggttgatgg taaaatcatc gtttcaaacc cagacatgga agcaactcta
     4801 aaagctgcct ttgaaaagat gattgacgaa gatagcgaga ttgtgactat ctttgttggt
     4861 gaagaaggtg accaagactt agcagaagaa cttgctgggt atttaggaga gacttacgaa
     4921 gatgtggaag ttgagatcca tcaaggagat cagcctgttt acccatatct catgagtgta
     4981 gaataataga atacaataaa aaaagaggag ttaggcaaag gtctgactct ttttgtctat
     5041 attgatgtcg taatgagtgg ttttagtgat ggtaagcccc taaaaaatga gggtaatcca
     5101 tcacaaagct aatggttacg atttaatttg acaaaaccta gaaaaacatt ataattgtat
     5161 tataacaata agtcaaggac tgaaaacggt tcagttctaa gacattacaa ggaggagatt
     5221 ttatgttagg accatttatc tttattgctt ttggggttat tgtaatccta gctattgttg
     5281 ccagtaccct ttatgttgtt cgtcaacaat ctgttgccat cgtggaacgt tttggtaggt
     5341 accaaaaaac agccactagt ggtattcatg tccgccttcc gtttgggatt gacaaaattg
     5401 ctgcgcgtgt gcagctgcgt cttttacagt cagaaatcat cgttgaaacc aaaaccaagg
     5461 acaatgtgtt tgtaactttg aatattgcca ctcagtatcg tgttaacgaa caaaatgtaa
     5521 cagatgctta ctacaaatta atgaaacctg aatctcaaat caagtcttat attgaagatg
     5581 ccttgcggtc atccgtgccg aagttgacct tagacgaatt gtttgagaaa aaagatgaaa
     5641 ttgccttgga agtacaacat caagtggcag aagaaatgtc aacctatgga tatattattg
     5701 tcaaaacctt gattaccaag gtggagcctg atgctgaagt caaacagtca atgaatgaaa
     5761 tcaatgcggc tcaacgcaaa cgtgtagctg ctcaagagtt ggcaaacgca gataaaatta
     5821 aaattgtgac agcagcagaa gcagaggctg aaaaagatcg attgcacggg gtagggattg
     5881 cccaacagcg taaggccatt gtggatggtt tggcggagtc tattcaagag cttaaagaag
     5941 cgaatatttc cttaaacgaa gaacaaatca tgtccatttt gttgaccaac caatacctgg
     6001 ataccctcaa tacctttgcg gcaaaaggaa accaaaccct ttttctacca aatacaccaa
     6061 gtggggtaga ggatatccgt acacaagttt tatctgccct taaaacaaaa taacgtgtaa
     6121 aagcttggct aaaaagttgc tcaatactgg atttagcaga aggctatcat accttgtgaa
     6181 gtggcaaacg acgaaatgaa tacattactt ttattggaga aatgaaagta aaaaaagcct
     6241 ttttcatgat taacaatata gtattgatta aatgttaagt tgtattgact tttaaattaa
     6301 ataagtttaa aatcaactta ataagcaaaa aggagatttt caatgaaatc caaaaaagtt
     6361 gttagtgtta tatcacttac cttatccctt tttttggtga caggttgtgc taaagttgat
     6421 aacaacaaat cagttaatcg taagcctgct actaaacaaa cctataatag ctatagtgat
     6481 gaccaattaa gatcgcgtga aaataccatg tctgttttat ggtaccagcg agctgcggaa
     6541 actcaagcgc tttatttaca ggggtatcag ttagcaacgg atcgcttaaa agaacaactc
     6601 aataaaccaa cggataaacc ttattcaatt gtattagata ttgacgaaac agttcttgat
     6661 aatagccctt atcaagctaa aaatgttttg gaaggaacag gatttacacc tgaaagctgg
     6721 gattattggg tacaaaagaa agaagcaaaa ccggttgctg gtgctaaaga ctttttgcaa
     6781 tttgcagacc aaaatggtgt tcaaatttac tacatttcag acagatcaac tactcaagta
     6841 gatgctacaa tggaaaatct ccaaaaagaa ggtattccag tacaaggtcg tgatcatctt
     6901 ctattcttag aaaaaggagt aaaatcaaag gagagtcgtc gtcaaaaggt caaagaaaca
     6961 actaatgtaa cgatgctatt tggtgataat cttctagatt ttgctgattt ttcaaaaaaa
     7021 tctcaagaag atagaacagc tttattatca gatttgcaag aagagtttgg aagacgcttt
     7081 atcattttcc ctaatcctat gtatggttca tgggaaggtg ccatttataa aggtgaaaag
     7141 ctggatgtgc ttaagcaact agaggaacgc cgtaaaagtt taaaaagctt taaataaagt
     7201 aattgaaaaa gaggtgcaaa agaaaatgta acctcttttt aagtactatt attttctgaa
     7261 aatagggtta atgactgaaa aaaatgttga ttttgtgaaa tgattatttt attattttca
     7321 tattttatct ttatgctagg aattgtggta taatggagga gtataaaaaa tattaaggag
     7381 tctattcaca tggctaaatt gactgttaaa gacgttgatt tgaaaggtaa aaaagtcctc
     7441 gttcgtgttg actttaatgt gcctttgaaa gacggcgtta tcactaacga caaccgtatc
     7501 actgcggctc ttccaacaat caagtatatc atcgaacaag gtggtcgtgc tatcctcttc
     7561 tctcaccttg gacgtgttaa agaagaagct gacaaagaag gaaaatcact tgcaccggta
     7621 gctgctgatt tagctgctaa acttggtcaa gatgttgtat tcccaggtgt tactcgtggt
     7681 tcaaaattag aagaagcaat caatgctttg gaagatggac aagttctttt ggttgaaaac
     7741 actcgttttg aagatgttga cggtaagaaa gaatctaaga atgacgaaga acttggtaaa
     7801 tactgggctt cacttggaga tggaatcttc gttaacgatg catttggtac agcacaccgt
     7861 gctcacgcat caaacgtagg tatttcagca aacgttgaaa aagctgtagc tggtttcctt
     7921 cttgaaaacg aaattgctta catccaagaa gcagttgaaa ctccagaacg tccattcgta
     7981 gctattcttg gtggctcaaa agtttctgat aagattggtg ttatcgaaaa tcttcttgaa
     8041 aaagctgata aagttcttat cggtggtggt atgacttaca cattctacaa agctcaaggt
     8101 atcgaaatcg gtaactcact tgtagaagaa gacaaattgg atgttgctaa agacctcctt
     8161 gaaaaatcaa atggtaaatt gatcttgcca gttgactcga aagaagcaaa cgcatttgct
     8221 ggttacactg aagttcgcga cactgaaggt gaagcagttt cagaaggctt ccttggtctt
     8281 gacatcggtc ctaaatcaat cgctaaattt gatgaagcac ttgctggtgc taaaacagtt
     8341 gtttggaatg gtccaatggg tgtctttgaa aaccctgact tccaagctgg tacaatcggt
     8401 gtcatggacg ctatcgttaa acaaccagga gttaaatcaa tcatcggtgg tggtgattca
     8461 gcagctgctg ctatcaacct tggccgtgct gacaaattct catggatcag taccggcgga
     8521 ggcgctagca tggaacttct cgagggtaaa gtattaccag gtttggcagc attgactgaa
     8581 aaataatagt cattataata tatagtaaag ggcatgctga tgcatgtctt tttttagttg
     8641 atcatgtaga gttattgaac tttccctaac ttcacttatc atttactagt ttttagatat
     8701 agtggtattt ggctgacact tcaattttca aaagtttatg acgatttcat atcaattggt
     8761 ttataaaaga tatcctaatc ataaataaaa cgtttaccaa aagggtttta tgg
//
LOCUS       DAUCXI010000058         8501 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.058, whole genome shotgun sequence.
ACCESSION   DAUCXI010000058 DAUCXI010000000
VERSION     DAUCXI010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8501
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.058"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            78..2597
                     /gene="secA"
                     /locus_tag="VGY43_001592"
     CDS             78..2597
                     /gene="secA"
                     /locus_tag="VGY43_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEQ4302758.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
     gene            2713..3069
                     /locus_tag="VGY43_001593"
     CDS             2713..3069
                     /locus_tag="VGY43_001593"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEQ4302759.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLSYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            3066..4166
                     /locus_tag="VGY43_001594"
     CDS             3066..4166
                     /locus_tag="VGY43_001594"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEQ4302760.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANAIT
                     VTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLIDSLKELGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            4253..5782
                     /locus_tag="VGY43_001595"
     CDS             4253..5782
                     /locus_tag="VGY43_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ4302761.1"
                     /translation="MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSDNKA
                     EAENQVDDKSTDHSKPTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEVRTPI
                     QSLSPYVSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKS
                     TGIAYDSTRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAF
                     DLDPTQASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFT
                     DTTGSGKRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLG
                     YQASSYSWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAP
                     GQAGADGTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSK
                     N"
     gene            6272..>8501
                     /gene="shr"
                     /locus_tag="VGY43_001596"
     CDS             6272..>8501
                     /gene="shr"
                     /locus_tag="VGY43_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEQ4302762.1"
                     /translation="MKKISKCAFVAISTLVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKINANLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKPVPQN
                     QGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSKGFEDVIITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKH
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKSNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEELSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLS"
BASE COUNT         2794 a         1477 c         1772 g         2458 t
ORIGIN      
        1 taactttacc aacctttctt gaactgcctg catatttatg ttaaaatgaa atgattagat
       61 gatcgaaagg aaagagaatg gccaatattc tacgcaaagt tatcgaaaat gacaaaggcg
      121 aactaagaaa attagaaaaa attgcaaaaa aagtagaatc ctacgcagac caaatggcgt
      181 cattgtcgga tagagatcta caaggaaaaa cacttgaatt taaagaacgc tatcaaaaag
      241 gtgagaccct cgaacaacta ttacctgaag ctttcgcagt tgttcgtgaa gcagcaaaac
      301 gtgtgttggg cttgttccct tatcgtgttc aaattatggg aggaattgtt cttcataacg
      361 gggatgtccc tgaaatgcgt actggtgaag gaaaaactct tacagccacc atgccagttt
      421 atctcaatgc tattgctggt gagggtgttc acgttattac tgttaatgag tatctttcaa
      481 cgcgtgacgc taccgaaatg ggtgaagtgt atagctggtt aggtctttca gttgggatca
      541 acctagctgc taagtctcct gctgaaaaac gtgaagctta taattgtgat attacttatt
      601 caaccaactc tgaagtcggt tttgattacc ttcgtgacaa catggttgtt cgccaggaag
      661 acatggtaca acgcccactc aattttgcct tggttgatga agtggactca gtcttaattg
      721 acgaggcaag gacaccttta attgtttctg gtgctgttag ctctgaaacc aatcaattgt
      781 atattcgtgc tgacatgttt gtaaaaactc tgacgtcagt ggattatgtt attgatgtgc
      841 ccactaaaac gattggatta agcgattcag gtattgataa agctgagagt tattttaact
      901 tgagcaatct ttacgatatt gaaaatgtag ccttgactca ctttatagac aacgcccttc
      961 gtgcaaacta tattatgttg ttagatatcg attatgtggt cagcgaagat ggtgagattc
     1021 ttattgttga ccaatttaca ggtcgtacga tggaagggcg tcgcttctca gacggcttgc
     1081 accaagctat tgaggcaaaa gaaggcgttc gtattcagga agaatcaaaa accagcgcct
     1141 caatcactta ccaaaatatg tttcgtatgt acaaaaaatt ggcaggtatg actggtactg
     1201 cgaagaccga ggaagaagaa tttcgcgaag tttataatat gcgtattatt ccaattccaa
     1261 ccaatcgtcc aattgcccgt attgatcaca ctgatttgct ttacccgacc ttagaatcga
     1321 agtttagagc agttgtggaa gacgttaaaa cgcgtcatgc aaaaggacaa cctatccttg
     1381 taggtacggt tgctgttgaa actagtgatt tgatttcacg caagctggtt gaagcaggga
     1441 ttcctcatga ggttttgaat gctaaaaatc actttaaaga agctcaaatc attatgaatg
     1501 ctgggcaacg tggtgctgtt acaatcgcaa ctaacatggc tggtcgtggt actgatatca
     1561 agcttggtga aggtgttcgt gaacttggtg ggttatgtgt cattggtaca gagcgtcatg
     1621 aaagtcgtcg tatcgataac cagcttcgtg ggcgttcagg tcgtcaagga gatccaggtg
     1681 aatcccaatt ctatctttca ttagaagatg atttgatgag acgtttcggc tctgatcgta
     1741 taaaagcctt tttggatcgg atgaaattag atgaagaaga cactgttatt aaatcaggta
     1801 tgttagggcg tcaagtggaa tctgctcaaa aacgggttga aggaaataac tacgataccc
     1861 gtaaacaggt cttacaatac gatgatgtga tgcgtgaaca gcgtgaaatt atctatgcta
     1921 accgtcgtga tgtcataact gctaatcgag atcttggccc agaaattaaa gctatgatca
     1981 agcgtactat cgaccgtgct gtagatgctc atgcacgtag caatcgtaaa gatgctatag
     2041 atgctattgt aacttttgct aggacctcgc tggtaccaga agagtctatt agtgctaaag
     2101 agttacgtgg tttaaaagat gatcaaatca aagagaagct ttatcaaaga gcgcttgcta
     2161 tctatgacca gcaactatca aaacttcgtg atcaagaagc tattattgaa ttccaaaaag
     2221 tactcatttt gatgattgtg gataacaaat ggactgaaca cattgatgcc ttagatcaac
     2281 ttcgtaatgc tgttgggctt cgggggtatg ctcaaaataa ccctgtggtg gaataccaag
     2341 cagaaggttt caagatgttc caagatatga ttggtgccat cgagtttgat gtaacacgta
     2401 ccatgatgaa agcacaaatt cacgaacaag aacgtgaacg tgcaagtcaa cgtgccacaa
     2461 cagcagcacc tcaaaacatc caatcgcagc agtcagctaa caccgatgat ttacctaaag
     2521 tggagcgtaa cgaagcttgt ccatgtggtt caggcaaaaa attcaaaaat tgtcacggtc
     2581 gtaaatcctt ctcataagaa cgagacacaa caggacaaag ttaggtatat agaaagaagc
     2641 tgagaataat tctcagcttc tcactgttta aatcttctaa cattaagatg aaataaggtt
     2701 tggtggaaag taatgattgt tggacatgga atagacttac aagagatttc agctattgaa
     2761 aaagtttatc aaagaaatcc tcgctttgct caaaaaattt taactgagca ggaattggct
     2821 atttttgaga gttttcctta caaacgtcga ctcagctatt tggcaggacg ctggtcaggt
     2881 aaggaagctt ttgctaaggc tatagggaca ggtattgggc ggttaacctt tcaagatatt
     2941 gagattttaa atgatgttag aggatgtccc attctgacaa aatctccgtt taaaggaaat
     3001 agttttatta gcatctcaca tagtggcaat tatgtacagg ctagtgttat tttggaggat
     3061 aaaaaatgat ttcaagtttc catcgcccaa cagttgcaag ggtcaattta caagctatta
     3121 aggagaatgt tgccagtgtt caaaagcata ttccactagg ggtaaaaacg tatgcagttg
     3181 tcaaggctga tgcttatggt catggtgctg tccaggtgtc aaaagcactc ctacctcaag
     3241 tggatgggta ctgtgtgtca aatcttgatg aggctttgca attacgtcaa gcaggtattg
     3301 ataaagagat tttaattctt ggggtcctcc tgccaaatga attagagtta gcagttgcta
     3361 atgctattac tgttacaatc gctagtttag actggatagc tttagctaga ctggagaaaa
     3421 aagaatgtca aggcttaaaa gttcatgtaa aagttgattc tggtatgggg cggatcgggc
     3481 ttcgttcttc aaaagaagtc aatttattga ttgatagtct aaaagagttg ggtgctgatg
     3541 tagaaggtat ttttactcat tttgccacag ctgatgaggc agatgatact aaatttaacc
     3601 agcagttaca gttttttaaa aagctgatag ctggacttga ggataagcct cgtttagtac
     3661 atgctagtaa ttcagccaca agtatctggc atagtgatac catttttaat gctgttcgtt
     3721 taggaattgt cagttatggt ttgaatccaa gtggttctga tctaagctta ccatttccac
     3781 tgcaagaggc tttatctcta gaatctagct tagtgcatgt caagatgatt tcagctggtg
     3841 atacagtcgg ttatggagct acttatactg ccaaaaagtc tgaatatgta gggaccgtcc
     3901 caatcggtta tgcagatggc tggaccagga acatgcaagg cttttcggtg ttagttgatg
     3961 gacaattctg tgaaattata gggcgtgtat cgatggatca actgaccata cgacttccca
     4021 aagcatatcc tttaggaaca aaagtcactt tgattggcag caatcagcaa aaaaatattt
     4081 ctacaacaga tatcgcaaat taccgtaata caatcaatta tgaagttcta tgccttttaa
     4141 gtgaccgtat tcctcggata tattaagaaa atcacgtaaa aataattgca ttgtgcttat
     4201 ctttaatgtt ataataaagt gaggacatta gaaagaagtg actaattaat atatgaataa
     4261 aaacaaacta ttaagagttg ccatgctact aagtctctta gccccgacag cagaaagcat
     4321 gacagtgttg gctcaagatg taatgcttga gacgcataaa gcaactacaa atgaaaccag
     4381 tgattcttct tcaaaagagg aaaataataa aaatgcagca cctacaacat cagataaaac
     4441 tgaccaaggt ccccttgatg cttctgcaga aacaaactct aatagtcttg ttaacgcgga
     4501 tgataaaaaa agaagcgatt ctagtcagtc tgctgtaggt tcttcggaca acaaggcaga
     4561 agcagaaaac caggtagatg ataaatcaac tgaccattcg aaaccaactg atcattcgaa
     4621 accaactgac cagccaaaac cgactgatca gcccaaacca tcaccatcta aagttgatac
     4681 ggcacctgct tcttcattgt cgagacagtt gccagaggta agaactccta ttcagtcgtt
     4741 gtcaccttac gtatcagatt tagatttgag tgagatagat atcccttctg tcaacacata
     4801 cgcggcatat gtagagcatt ggagtggtaa aaatgcctat acccaccatc ttttatctcg
     4861 ccgttatggt attaaagctg accagattga tagttactta aaatcaacag gcattgccta
     4921 tgacagcaca cgtattaatg gtgaaaagct attgcaatgg gaaaagaaaa gtgggctgga
     4981 tgttcgagct atcgtagcta ttgcgatgtc tgagagttct ttaggaactc aagggattgc
     5041 gactttgctt ggagctaata tgtttggcta tgcagctttt gatctagatc cgactcaagc
     5101 aagtaagttt aatgatgata gtgctattgt caaaatgaca caagatacca ttattaaaaa
     5161 caaaaatagc aattttgcac ttcaagattt aaaagcggct aagttttcac gaggtcaatt
     5221 aaactttgca agtgacgggg gtgtttattt tactgatact actggtagtg gtaaacgtcg
     5281 cgcacaaatt atggaagacc tggataagtg gattgatgac catggtggca caccagccat
     5341 tccagccgaa ttgaaagtgc agtcatcagc tagttttgca tctgtgccag caggttataa
     5401 gctctctaag agttatgatg tcttgggtta tcaagcttcg agttattctt ggggacaatg
     5461 cacttggtat gtgtataatc gcgccaaaga attgggttac caatttgatc cttttatggg
     5521 aaatggtgga gattggaagt ataaagcagg gtatgccctg tcaaagactc caaaagtagg
     5581 ttatgctatt tcatttgcac ccgggcaagc aggcgctgat ggcacttatg gccacgtatc
     5641 aattgtagaa gatgttagaa aagatgggtc tattcttatt tcagagtcta actgtatcgg
     5701 cttaggtaag atttcttatc gtacctttac agctcagcag gctgaacagc taacatatgt
     5761 tattggcaag agtaaaaact aataactaat gacttttctt acggcttaat tttcttagcg
     5821 ggagttaggc cttttaaact gttggtgtaa cacgacaaag tttcaagtaa ataaatgatt
     5881 ttgagacaat agcacgatta aggctattgt ctttttttat tgtgatgaat atgcagtagt
     5941 gacatctcat gttgtctcct aacacaatta tggagcttat aacgtgttac atgttttgtg
     6001 aatgaagtaa tgattgaatc agccctagta ataactatcc taaggctagc tttatctcag
     6061 taatattgtt gtagaggaat tcttttatca gagatatcct cattatcaat tcaggcttat
     6121 tgctagtgtc ttggctcaca tagtggagct ttttaacaga caattggacc attggaaaca
     6181 atcttgacaa aataatcaca aagtgataga ttaagttcag ttaataaaaa agttagctta
     6241 ttcataaaaa tttttagaaa gttgattgaa aatgaaaaaa atcagcaaat gtgcgtttgt
     6301 ggcaatatct acccttgttc tcattcaggc tactcaaact gtaaaatcac aagagccttt
     6361 agttcagtca caactcgtga caacagtagc tttaactcag gataatcgac ttttagttga
     6421 agagataggc ccttacgcta gtcaatcagc tggaaaagag tattataaac atattgaaaa
     6481 ggttattgtt gataatgatg tctatgaaaa aagcctggaa ggcgagcgaa cctttgatat
     6541 taactaccaa gggattaaga tcaatgctaa ccttattaaa gacggtaagc atgaattgac
     6601 tattgttaat aaaaaagatg gtgatatcct aattaccttt attaaaaagg gcgataaagt
     6661 gacctttatt tcagctcaaa aattaggaac aacagatcat caggattcat taaaaaaaga
     6721 tgtgctcagt gataaaccag tgccacaaaa ccaaggcaca caaaaagttg ttaaatctgg
     6781 gaaaaatact gctaacttgt cattaataac aaaattgagt caagaagatg gtgcaatttt
     6841 atttccagaa attgatcgtt attctgataa caaacagata aaagcattga ctcagcaaat
     6901 cacaaaggtt acagtcaatg gtacagttta taaagatctt atttcagatt ctgtaaaaga
     6961 tactaatggc tgggtctcga atatgacagg gcttcatctt ggaacaaaag ctttcaaaga
     7021 tggagaaaat acaatcgtga tatcctcaaa aggatttgaa gacgttatca ttaccgttac
     7081 caagaaagat ggtcaaatcc attttgtatc tgccaaacaa aaacaacatg tgactgctga
     7141 agacagacaa tcaacaaagt tggatgtcac cactttggaa aaagctatca aagaagcgga
     7201 tgcgattatt gctaaagaaa gcaacaaaga cgcggtcaaa gatctggctg agaaacttca
     7261 agtcatcaag gattcttaca aagaaatcaa agatagtaag ctactcgccg atactcatcg
     7321 actgttaaaa gataccatcg agtcttatca agcaggtgag gtttctatta acaatctcac
     7381 agaaggaacc tatacgctaa actttaaagc taataaagaa aactcagaag agtcctccat
     7441 gcttcaaggt gcttttgata aaagagccaa attagtggtt aaagcagatg gtacaatgga
     7501 aatttccatg cttaatactg ctttgggaca atttttgatt gacttttcta ttgaaagcaa
     7561 agggacctac ccagcagcag tgcgtaaaca agttggccaa aaagatatca atggtagcta
     7621 tattcgaagc gaatttacca tgcctattga tgatttggat aaattacaca aaggtgctgt
     7681 tttggtatca gccatgggag gtcaagaaag tgatttaaac cactatgaca aatacaccaa
     7741 acttgacatg acctttagta agaccgttac caaaggttgg agtggttatc aggtagaaac
     7801 tgatgataaa gaaaaagggg ttgggactga acgtcttgaa aaagttttag ttaaacttgg
     7861 caaagattta gacggcgatg gtaaattatc aaaaacggaa ttagaacaga ttcgaggtga
     7921 gttgcgtcta gaccattacg agttaacaga tatttcttta ttgaaacatg ctaaaaatat
     7981 tacagaacta catctggatg gaaaccaaat tacggaaatt ccaaaagagt tatttagtca
     8041 aatgaagcaa cttcgatttc ttaacttaag aagtaatcat ttaacttatc tagacaaaga
     8101 tacatttaaa agcaatgctc aattaagaga actctactta tcaagtaact ttattcactc
     8161 tcttgaagga ggactattcc agtcgcttca tcacctggag caacttgatc tttccaagaa
     8221 tcgtattggc cgactttgtg ataacccatt tgaagaattg tctcgtctga cttcattagg
     8281 tttcgcagaa aatagtcttg aggagatacc tgaaaaagcg ctagagcctc taacatcact
     8341 taattttatc gacttatctc aaaataattt agcactactg ccaaaaacaa tagaaaaatt
     8401 gcgcgcctta agcactattg tggcaagtag aaatcatatt actcgtattg ataatatttc
     8461 atttaaaaat cttcctaaat tatctgtact cgatttatca a
//
LOCUS       DAUCXI010000059         8343 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.059, whole genome shotgun sequence.
ACCESSION   DAUCXI010000059 DAUCXI010000000
VERSION     DAUCXI010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8343
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.059"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..918)
                     /locus_tag="VGY43_001597"
     CDS             complement(<1..918)
                     /locus_tag="VGY43_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302763.1"
                     /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAEISTATM
                     TQQERAEKIKKIKDYITKYPKTTEERFWNRTWIRDYFKDEDYLKAVQSFTEQALENIL
                     ELIEKGATKGEKGDAGPAGPRGERGPQGKAGEKGETGPRGERGEQGIQGEQGKAGEKG
                     EKGDKGDTGERGEKGETGATGAQGPQGEAGKDGAPGEKGEKGDRGETGAQGPVGPQGE
                     KGETGAQGPQGEAGQPGAQGPAGPQGEAGKPGEQGPAGPQGEAGQPGEKAPEKIPEGE
                     AGQPGEKAPEKSPEVTPTPETPEQPGEKAP"
     gene            1300..1782
                     /gene="nrdI"
                     /locus_tag="VGY43_001598"
     CDS             1300..1782
                     /gene="nrdI"
                     /locus_tag="VGY43_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEQ4302764.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFSLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
                     "
     gene            complement(2176..2994)
                     /locus_tag="VGY43_001599"
     CDS             complement(2176..2994)
                     /locus_tag="VGY43_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEQ4302765.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIICLQEINQL
                     IESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIHVSDILVSAMDDETDYHTRRSLIAKTTLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLDLQDSHKVAAHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKITFEGGDAPVVSDHYGLEVTLDWR"
     gene            complement(3077..5263)
                     /locus_tag="VGY43_001600"
     CDS             complement(3077..5263)
                     /locus_tag="VGY43_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEQ4302766.1"
                     /translation="MKTSFKQLFRFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHDSAFLASLGNIIAQIGWAVIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAFYGVSSAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSIFVALILVVVWPVIQSGINSFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSVLFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDRNTQARPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDP
                     AKVGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGAVIPEVNMSQLT
                     SKPTPAKDFKHVTEDVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTNGNIYAPVA
                     GLVTSVFPTKHAFGLLTDNGLEVLMHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIKSAERETTIVVAFTNTAEIQDVTLTSLGNQPAKTKVATVEL"
     gene            complement(5620..6369)
                     /locus_tag="VGY43_001601"
     CDS             complement(5620..6369)
                     /locus_tag="VGY43_001601"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEQ4302767.1"
                     /translation="MQQYFIKGKAEKKVTITDKDTIKHMFQVMRLTDEAEVVLVFDDG
                     VKYLAKVTSSMAHELEIIEALPDQVELPVEVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYSADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEHKEEFLKNLPS
                     FDHIFVAYEETAKAGQLATLAREVKEVKPGAKILFIFGPEGGISPTEITQFEAAGAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            complement(6369..7322)
                     /locus_tag="VGY43_001602"
     CDS             complement(6369..7322)
                     /locus_tag="VGY43_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEQ4302768.1"
                     /translation="METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYTGQKD
                     RFGELYPDVEQSDMIAITAYYPSSTNLADVIATINEQLAELVSFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASAGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQDNIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMIQGEWNALVFKKTDDISGVIGG"
     gene            complement(7339..>8343)
                     /locus_tag="VGY43_001603"
     CDS             complement(7339..>8343)
                     /locus_tag="VGY43_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302769.1"
                     /translation="GIFKSVLDILISIWIVLKLPISQWVSVANIFYIVLIYYVTKNDI
                     ELSYWYIKDYVIIFLFTIFPAILLLKESSVVEIIRNQWRELLMFNTALLFISNTYTFS
                     LPIELLLVFLLIILSIFSAVIDTKKELQQPGRLFSFLLSIVGLIMLLGALKQFLDNLS
                     DIKSFDFWLSYAFELLVILINLPVLYIAQKMIIIEKIIVHSEYPNTIVSFMRYYYKWY
                     CRKIKFKKLIVKDYNLDIAVQKYIFGYPKISVYVKEGNLSKEKVLNLIALIIVKGDKK
                     EKLSRRIDRFPVYIEVVDKENQTVALWTEEFLSKQNYFYDPFMTKNTKEIYPSILMLQ
                     "
BASE COUNT         2274 a         1934 c         1585 g         2550 t
ORIGIN      
        1 tggagctttt tcacctggtt gctctggcgt ttctggcgtt ggtgtcactt ctgggctctt
       61 ttctggagct ttttcgcctg gttggcctgc ttcgccttct gggatctttt ctggagcttt
      121 ttcgcctggt tggcctgctt caccttgtgg gcctgctggg ccttgctcac ctggtttgcc
      181 tgcctcacct tgtgggcctg ctgggccttg tgcgcctggt tggcctgctt cgccttgtgg
      241 gccttgtgcg cccgtttcac ctttttcacc ttgtgggcct actggacctt gagctccggt
      301 ttcaccgcgg tcaccttttt cacccttttc gcctggagct ccatctttac cagcttcacc
      361 ttgtgggcct tgtgcgccag ttgctccggt ttcacctttt tcaccgcgct caccggtatc
      421 acctttgtcg cctttttcac ccttctcgcc agctttacct tgctcgcctt ggattccttg
      481 ttcaccgcgc tcacctctcg gaccggtttc acctttttca ccagctttac cttgtgggcc
      541 gcgttcgcct cgaggtcctg ctgggccagc atcccctttt tcaccttttg ttgcaccttt
      601 ttcaatcagt tctaaaatat tttcaagtgc ttgttcagta aaactttgta ctgcttttaa
      661 ataatcttca tccttaaaat agtcacggat ccaggtccga ttccaaaatc tttcttcagt
      721 ggtttttgga tatttggtaa tatagtcttt aattttttta attttttcag ctctctcctg
      781 ctgtgtcata gtcgcagtag aaatctcagc cttaacgctg cttgccccgc ctccaaaggc
      841 tagaaggacg gcagcggctg aggttagccc gtagcgccag accagtttgt tgagattatg
      901 gtgctttgat gtcaacatat gttgttctct ctttctttat tagatggtgt gttttagata
      961 aaaataacat ggtagctaga cctgattatt tataatagta ttataataga gtgtgaaaac
     1021 gattgtaaag ttctcttttg ttgttcatct tttagatttt gactgatcgc tcttttgtgg
     1081 agatcagagg gccactttag cacttgcctg cctcgttttt aagttgtggg catccggatc
     1141 ctttctttaa ggtcactctt ttttgaaatg ttactttttt tgactgcttg taccttcttg
     1201 tctggttgga taccgctagg tttcttcttt acttgtttgt tggtcttgat tgtggtaagc
     1261 ttatgaagaa accttgtagg ataaaaaaag gagacactta tgcctcagat tacccttgtt
     1321 tttattagcc tcagtggcaa cacccttagc tttgtcaagc ggctatccct ttatctagca
     1381 gacaattacg attaccatgt caaacagatt aacattaaag atttgaagca cgagactttt
     1441 cccgtcaaag aagagtttgt ggcgattcta cccacttatc tagaaggcgg aaatggcgtt
     1501 gactctggtg aggtggagat cctcaccact cctttgggag agtttattgc tgcccatggc
     1561 aacgcccagc gttgtcttgg gattattggt tcaggcaaca aaaactttaa ccatcagtat
     1621 tgcctgacag ccaaacaata tgccaaacgc tttggctttt cactgctagg tgattttgag
     1681 ctgcgaggga ctcctgatga catttcccgg ttagcccagg tcatcatgga ggctagctcc
     1741 agacactcat ctaacgacac acagacactg cccaacagct agacagtcta tagatgatca
     1801 tagctgtttt aaaaaagagc gcttttagga caataactac agaggtctct taccccacgc
     1861 cttgtgattt ctcagccttt gaaaagagcg atcacagtgc ttcttggtgc ttgggatcac
     1921 accaagcact cctagaaata cccccatgca gactttagca aggcaactga acgcttggcg
     1981 gtactttctg tgaagctcag atggtgggtg acaaaaaagc cctggttttt tagggttact
     2041 gacatgacta aagaggtcta accagctcta ccttgagcta gttagacctc tttgtgttct
     2101 cctaatcccc ctagatgatc gcagtttctt atgtgtcttg gcttctccta tgtggtgtgc
     2161 ctgttagcac atgctctaac gccagtctaa tgtcacttct agaccgtagt ggtcactgac
     2221 gactggcgca tctccgcctt caaaggtaat cttagaagat cggatgatga agtccttact
     2281 ggtaaagaca tgatctacct tgagggcttc tttgttacct tgccagccat caatatcagc
     2341 cacgatgcta tgatcaccaa acacgtgtgc agctactttg tgactatctt gtaggtctag
     2401 ggggctaccc atcatcactt gataaccgtc ttgatccgtt ggattgttaa aatctcccat
     2461 aagtagcaag ggacagttta gtgtgagcag ctctttttct aatttctccc actcccctaa
     2521 aaaccctttg tcaaaccaag ataggtgcac attgacaaca gcgacttctt tgccatctaa
     2581 cgtggttttg gctatgagtg agcgtctggt gtggtagtct gtttcatcat ccatcgctga
     2641 cacgagaata tctgaaacat gaataggttg ttttgataag attgccacgc cttcctggta
     2701 aatgtcataa ccaatatggt tataagccca agaccaataa tagtgctgcc ctcgtttttg
     2761 taaataatgg atcaagagca gagcaaaatg gtctttatga atgcttggtg tccctgaaag
     2821 agcttgatat cttggtaaat ctgtggccag ctcgctctcg attaactgat tgatttcttg
     2881 caagcaaatg atatcgtatt tttcagctaa aatatgctca gccaaagcaa ctagtttttt
     2941 aagagtgttg gcttgcatcc acgaatgggt attcagtgtt aataccttgg tcattaatcc
     3001 tcctttataa gacaagaaga gccatagggc ctaaaccagc tatggctatt acctatcact
     3061 atctcgtgat gttttgttaa agttctacgg tggctacttt agtcttagca ggttgattgc
     3121 ctaaagaagt caaggtcaca tcttggatct ctgctgtgtt ggtaaaagca acaacaatgg
     3181 ttgtttcacg ctctgctgat ttaatagcag caagatctgc tacgactaat aggtcacctg
     3241 catgaacccg ttgcccttct gagactttga ctgaaaaagg cacaccattt aaggcgacgg
     3301 tatcaagtcc cacgtgcatc agcacttcaa gaccattatc tgtcagtaaa ccaaaggcat
     3361 gcttggtcgg aaagacactg gtcacaaggc cagctacggg tgcatagata ttaccatttg
     3421 ttggttcaac cgcaaaccca tctcccatca tcttagccgc aaacacctgg tctttcacac
     3481 ctgtgattgg gagaaccatc ccgtctgcca ctgatagcac atcttctgtc acgtgtttaa
     3541 aatcttttgc gggagtgggt ttgctagtga gctgtgacat attgacttct ggaataacag
     3601 cccctgagtc cagcaaatct tgaatatctg atttcaaaat atctgcttta gggccataga
     3661 ccgcttgaac gccgttgcct ttttggatca agcccatagc gccagctttt ttccaatcgt
     3721 cctcagcgcc aactttagcg gggtctttga ccgtcactcg taagcgcgtc atacaagcat
     3781 caacatcatc aatattgcct gccccaccaa ggagattaat gatttgtacg acttgagagt
     3841 tgctatctgc tacttgggta ggtcttgctt gagtgttacg gtcacccagt atatcggcat
     3901 cgtagttgcc taaacggcca gctgttgcga gatgcatttt cttgatcatc atatctgcaa
     3961 taaagtacat gataactgca aagaggacag aaacccaaac aaagttaatc acatccatgc
     4021 ctaggcctgc tttaagagcc ataggggtac gggttagtag ctcaatgttc ccaaatgagt
     4081 gaacacgaag gttcacaagg tcagccatag caaatgaagc tccttgaaca agagcataga
     4141 cgatgtaaag tggcattgct gcaaacataa ataggtactc aagtggctca gttacccctg
     4201 tcaaaaagac cgctgccgct gctgagatga acatcatttt gtatgtgtgt tttttatcgg
     4261 catctacatt gcggtacatg gctaaggcaa cccccatcaa tgttccggta gctccaatca
     4321 tttgtcctac cttaaagcga gctggagtca cactatccat taagtgacta taggctgaag
     4381 cgtctgatcc tttaaggtga acaaggtcag ttacccaagc aagccacaaa gggtcttgac
     4441 caaatacttt tgtccccgct gctgcacctg tcatgacctc ataagttcca ccaagagctg
     4501 tatagttcat tgggatcgtc aacatgtggt gaagaccaaa tggcaacaag agacgttcca
     4561 aggtaccata taggaatggg gctaggattg gagctgaatc ttgtgaagag gcaatccaca
     4621 tcccaaaact gttaatccca gactggatca ccggccaaac aacaaccaaa ataagggcta
     4681 caaaaataga acgtaaaata acgacaaacg gtacaaaacg cttcccatta aagaaggtca
     4741 aaacttcagg aagtttacgg taattatagt atttgttata ggccgttgct cctacgaacc
     4801 ctgcaataat cccaacaaaa acccctgtgt ttaaagctgg agattccaag acactggtga
     4861 aataatcttt aacgatcatt tgagtgccaa ggaggcttgt gatttttgct tctggatcag
     4921 ctagcatagc actagacacg ccataaaaag cacctgttat ccgattgatc aagacaaaag
     4981 caagacctga ggcaaaggcc cctccagctc tttctttagc ccaactacca ccaatggcca
     5041 aggcaaatag caaatgaagg tttacaataa cagcccagcc aatctgagcg ataatgttgc
     5101 ctagagatgc caaaaatgct gagtcgtggt taatcattgg aatagagttt ccgatactga
     5161 tcattaaacc agccgctggc atgacagcaa taacgaccat aagacatttc ccaaattttt
     5221 gccaaaattc gaaacgaaac agttgtttga atgatgtttt cattctatct ctcctttatt
     5281 atcccctttt agccatagct gcccttaagg cacttttgtg acacaatgat atagactaca
     5341 actcagtaat gcaatcgttt gcattgatct gataccttta ttatactagc ctcgcaacaa
     5401 tttgtaaagc gttttcttag acagatgtta gtcgtttttc ttcattaaat ggtagtgtaa
     5461 ctcaccaaaa atatgacaag agcccatttc cttttttggt gatgagccca tcaacgctct
     5521 tcaaaaaaac aagaagcaat aaaaaaaggc cgttgacaca atcgtgaact gcctgttcgt
     5581 ttctttagcc tcttctttct aaagtaagca gcagcttact tattttgatg cctgcaattc
     5641 caaagcataa ctaagagcac ttaaggcata tagcggcgct gtctctgctc gcataatgcg
     5701 agggcctaag cccaccttta tggcacctgc tgcctcaaac tgagtgattt cagttgggga
     5761 aattccccct tctggcccaa agataaagag gatttttgcc cctggcttaa cttcttttac
     5821 ttcacgcgcc aaggtcgcta actgacctgc cttggctgtt tcttcgtatg caacgaaaat
     5881 atgatcaaag ctaggaaggt tttttagaaa ctcttctttg tgttcaaaga ggtgaacttc
     5941 aggcacccta tttcgtttgc tctgctcagc cgctcctaat acaatcttag ccaatttgtc
     6001 ttctttttta gctaattttt tgccatccca tttgaccact gaccagtctg cggagtagcc
     6061 ccatagcgca ctggctccca attcagtcac tttctgggca atcgtgtcta acttatcgcc
     6121 tttaggaaat ccagaagcaa tggtcacctc aacaggcaat tccacctgat ctggcaaagc
     6181 ctctataatc tctaactcat gagccatact actggtcact ttggctaaat acttcacccc
     6241 atcatcaaat accaagacaa cttctgcctc gtcagtcaag cgcatcactt gaaacatgtg
     6301 cttgatggta tctttatcgg taatcgttac ctttttttct gctttgcctt taataaaata
     6361 ctgttgcatt agccgccaat cactcctgag atatcatctg tttttttaaa gacaagggcg
     6421 ttccactcgc cttgaatcat gtgtgtctca aggaagaagc ctgcgctaaa ggcagcttcc
     6481 agaaccatat ccaatttctc agaaatgatg cctgataaga taaggtaacc ttcctttttg
     6541 accaaacggt aagcatcatc agtcaataag actaagatat ctgccaaaat attagccaca
     6601 atcacatccg cttcttggct aacccctttt aaaaggtcac cagcagccac atgaatgttg
     6661 tctgttcctt ggtttaaatc aatgttgtct tgagccactc gaacagccac gtcatctaag
     6721 tcataagcgt agatggtttt agcacctagt aaggaactgg caatcgagag gacacctgat
     6781 ccggtcccta catcgataac tgtctcacca ccacgaagga cttgttccaa ggcaaaaagg
     6841 ctcatcttag ttgtgggatg tgtccctgtc ccaaatgcca ttccaggatc taacttaata
     6901 accttttccc cagcagaagc gtcataatct gtccaactag ggacaatggt taaatcatgc
     6961 gtgatacgag ctggttcata gtattttttc caattgtctg cccagtcttc ctcagccaat
     7021 tcctgactgt ccacagtaac ctgaccaacc tgtaacccaa aactaactaa ctccgctaac
     7081 tgttcattaa tggtcgcaat aacatccgcc aaattagtgc tacttgggta ataggctgtg
     7141 atagctatca tatcagactg ctccacatct gggtataact ccccaaagcg gtccttttgc
     7201 ccagtatagt ctgcgctatc cgcgatagcg accccttgac tgcctgtctc aatcaacaca
     7261 tgtgaaacag cctcttgcgc atcacgatgc acatgaaccg tcacttcttg ccacgtttcc
     7321 ataagtatgt cctttctcct actgcaacat taaaatcgat ggataaattt cctttgtatt
     7381 tttagtcata aatggatcat aaaaataatt ttgtttagat aagaactcct cagtccataa
     7441 tgctactgtt tgattctctt tatcaaccac ttcaatataa acaggaaatc tatctatcct
     7501 tcgagataat ttttccttct tatctccttt tacaattatt aacgctatta aattcagaac
     7561 cttctcttta gagaggttac cctctttaac gtatacagaa attttagggt atccaaaaat
     7621 atatttttgt actgcaatat ctaaattata atcttttact attaattttt taaattttat
     7681 ttttctacaa taccatttat aatagtatct cataaaacta acaatagtat ttggatactc
     7741 actatgaaca attatttttt caataattat cattttctgt gctatataca atactggaag
     7801 attaatcagt atgacaagta attcaaaagc atatgataac caaaaatcaa atgatttaat
     7861 atcggaaaga ttgtccaaaa attgttttaa cgcaccaagt agcattatca gtcctactat
     7921 tgataataaa aaagaaaata atcgaccagg ttgttggagt tctttttttg tatcaataac
     7981 agctgaaaat attgacaaaa ttatcaataa aaatactaac aataactcaa taggtagaga
     8041 aaatgtatag gtattactaa taaacaataa cgccgtattg aacattaata attctctcca
     8101 ctgatttctt attatttcta caacagagga ttcttttaat aataagatag ctggaaaaat
     8161 cgtaaataaa aaaataataa cataatcttt tatataccaa taagataact caatatcatt
     8221 ctttgtcacg taatatatta aaacaatata gaaaatatta gctacactta cccactgaga
     8281 tataggaagc tttaacacta tccagatact aatcaatatg tctaaaacac ttttaaaaat
     8341 tcc
//
LOCUS       DAUCXI010000060         8084 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.060, whole genome shotgun sequence.
ACCESSION   DAUCXI010000060 DAUCXI010000000
VERSION     DAUCXI010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8084
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.060"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(150..590)
                     /locus_tag="VGY43_001604"
     CDS             complement(150..590)
                     /locus_tag="VGY43_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEQ4302770.1"
                     /translation="MTSSTQACVFSGVKIALMQDQHLVTILRDNKSTIPFPDTWDLPG
                     GGREGLETPFECVQREVMEELGIAISQDMVVWEKAYQGVMNPETYSIFMVAMISKDLV
                     KAIHFGEEGQAYKFVPVKDFLADKKAVPQLQERLAAYLAEKSDQ"
     gene            complement(618..935)
                     /locus_tag="VGY43_001605"
     CDS             complement(618..935)
                     /locus_tag="VGY43_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEQ4302771.1"
                     /translation="MVLSPKPFEMIASGTKTIELRLNDEKRQKVQVDDAIVFVRTDDS
                     SQMLWTKVVELHYFDDFVQLYQSLPLDNCGYRKEELEMARPEDMERYYSQEQQAQYGG
                     SRH"
     gene            complement(949..1419)
                     /locus_tag="VGY43_001606"
     CDS             complement(949..1419)
                     /locus_tag="VGY43_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEQ4302772.1"
                     /translation="MAKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEMTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKADFFLEWNAQAFEEGQQGLEEGESYPYPRY"
     gene            1592..3565
                     /locus_tag="VGY43_001607"
                     /pseudo
     CDS             1592..3565
                     /locus_tag="VGY43_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
     gene            3750..5507
                     /gene="pabB"
                     /locus_tag="VGY43_001608"
     CDS             3750..5507
                     /gene="pabB"
                     /locus_tag="VGY43_001608"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEQ4302773.1"
                     /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKTLDQVGPVIEKVQHYQ
                     QLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIP
                     NQWVSATQKEAYQKAIETIHHEMRQGNTYQVNYTIQLTQELNAADSFAIYNKLVVEQA
                     AGYNAYIAHDEFAVISASPELFFKQEGNQLTTRPMKGTTKRGVNTWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQTGSVCVDRLCEVEQYSTVWQMTSTIVGDLKADCDL
                     IDILTALFPCGSITGAPKVSTMAIITSLEPNPRGIYCGTVGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHQKIAFL
                     EQHLNRLKEAATYFAYPYDEKALQKQLSTYLENKNNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN
                     LFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLELTHLDALLAKSQA"
     gene            5540..6106
                     /locus_tag="VGY43_001609"
     CDS             5540..6106
                     /locus_tag="VGY43_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEQ4302774.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKADA
                     LVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ
                     STIETQDPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            6139..7407
                     /locus_tag="VGY43_001610"
     CDS             6139..7407
                     /locus_tag="VGY43_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEQ4302775.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENGTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDSSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLLD"
     gene            7496..7692
                     /gene="ssrS"
                     /locus_tag="VGY43_001611"
     ncRNA           7496..7692
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VGY43_001611"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            7693..7765
                     /locus_tag="VGY43_001612"
     tRNA            7693..7765
                     /locus_tag="VGY43_001612"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7726..7728,aa:Lys,seq:ctt)
     gene            7980..>8084
                     /locus_tag="VGY43_001613"
     CDS             7980..>8084
                     /locus_tag="VGY43_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEQ4302776.1"
                     /translation="MKKTKLIFSLTSIFIAIISRPVFGLEVDNNSLLRN"
BASE COUNT         2395 a         1959 c         1536 g         2194 t
ORIGIN      
        1 accagaatca ataaaactat tatccatatt gtaactgcaa tttctctagt agtcatatac
       61 ctccatctaa tctctcaatc gtccttccaa actcccatag acttggccat ttctcacaat
      121 ccttaaacac tgaaatacca acactcatct cactggtcac ttttctcagc tagataagct
      181 gccaatcgtt cttgtaattg aggcacagcc ttcttatccg ctaaaaaatc cttcaccggt
      241 acaaacttgt aagcctgacc ttcttctcca aaatgaatgg ctttaacaag atccttacta
      301 atcatggcca ccatgaaaat agagtaagtc tccggattca taaccccttg ataagctttt
      361 tcccagacga ccatatcttg cgaaatcgca attcctagtt cttccatcac ttcacgttgc
      421 acacattcaa agggtgtttc taaaccttct cggcctccac caggcaaatc ccaggtgtca
      481 ggaaaaggaa tggtagactt attatctctt aaaatggtca caaggtgttg gtcttgcatt
      541 aaagcaattt tcaccccaga aaaaacgcat gcctgtgtcg atgatgtcat aatcgtctcc
      601 tctacagcac tgataactca atgccgacta cccccatact gggcttgctg ttcctgacta
      661 taatagcgtt ccatgtcttc tggacgagcc atctccagtt cttctttccg atagccacag
      721 ttatctaagg gtaacgactg gtaaagctga acaaagtcgt caaaataatg aagctcaacc
      781 acctttgtcc acaacatctg actactatca tctgttctaa caaatacgat ggcatcatca
      841 acttggacct tttgccgctt ctcgtcattc agacgcaatt caatcgtctt tgtacctgag
      901 gcaatcatct caaaaggttt aggacttagc accatctcgt gtgtcacctt agtaccttgg
      961 gtaagggtaa ctttctccct cttctaatcc ttgttgacct tcttcaaaag cttgcgcgtt
     1021 ccactccaag aagaaatcag ccttgctgtc atccgctaag aaatccatta aatcgctgtg
     1081 cccttcaata gcaacatcgt tgagaaattg cgcaaagtaa gctaagaatt cacgagaaaa
     1141 gcccttttta gcgtcaaaag gaatagtaac caaataatct gctgcatcaa attgagactt
     1201 ggcagggttg taaaagagca catagtcctc aaagacaata tcatcttggg tcatttcgcc
     1261 actatcatca atggttttta tggcctcttt attttgagct tctaaaacaa aagtcacttc
     1321 aaccgcatga tttttcttgt cccaatccat agcataatca tactgaaaat gcttatccat
     1381 ttcttcttct aatactgata aaaagccata ttttgccatc taattgtcct ttttcctaac
     1441 gattatttgc ttccattgta gcataatttg aactaacttt cactggcaaa tgctgactga
     1501 tgggccttct gtattttagt aagcgtttta ccccttactt tcctcccatt atgttaaact
     1561 aataagcgat tatgatgtta ggagaaaaag aatgagatat tctagacgct acccttctca
     1621 gacaagacag atgcttcttg ccttgttatt aatgactgcc agcctacaag ctggagctat
     1681 gactacttat gcggatgagg ttaataccaa ccatcaacca ctaacggccc aagtggaagc
     1741 tagtaagccg acagccatgg aatctgtcac ttcacctgca gaccagaccc atccaatctc
     1801 aacgcaagag gcttcgtctc ctttacaccc tttaacaaca gaggccactc ctgccgccca
     1861 agaatctccg attaccttag aagactataa ggtagccagt gcgagccaat tagctgagtg
     1921 ggctcgccag caacgggtca caggccaaca gctgctagat tttgccttgg aaaccatcaa
     1981 agaaactaac cctgagctca ataatgtcat ttctctgcgt gaaccattgg ctcgacaaga
     2041 gagcgagcaa atgacagatg aggggcaacc cttttacaag gttcctattc tggttaaagg
     2101 gttaggacac accgttgctg gaagtagcaa caccaacggg cttgcctttt tgaaagacaa
     2161 aaccagctca tctaccagcg cctttgtcaa acaactccaa aaggctggtt ttatcgtggt
     2221 agggcagtcc tctttccctg aaatgggatg gattaatgtg acgaattcca atctttacgg
     2281 aaatacacat aacccatggc agcttgacca aaatcctggc gggtcctctg gtggctctgc
     2341 agctgctgtg gcttcaggac aagtcagtct agccagtgct tctgatggtg ggggctcaac
     2401 ccgcattcca gcttcttgga gtggcttgat tggcctacac ccaacacgtg gcattttaga
     2461 gggaaatccg acttctgaac gtagtaatgt tagtcatttt gctctaacta agagcatgga
     2521 agacactgaa aagctcttcc aattcctctt aaaagacaag gctaaagcgc aacaaaaccc
     2581 acagcgttta gacacaagta tccccattgc ttacagcacc cagacaccag cttgaacacc
     2641 aattagtgag gaagctattg ctgcgatcaa agaagctgta gcctttttac agaagcaagg
     2701 ttatcaaacc gtagaagtgc cttaccccgt tgatggtaag ctcatgatgc aatactatta
     2761 cactattgct gcttctgcag cgccatctat caattttatg gcacaacaaa ccttgaaacg
     2821 cccccttcaa aaagaggatg tcgaactcct atcatgggcg ctctaccaaa ctgggaaaga
     2881 cttgaccaaa gaggatgtca acaaagcctg ggagggtatc gcagccatga ccgagcaatt
     2941 aaaccagttc taccaaaaat accccatctt cttaacaccg acaacagcct atcccgcccc
     3001 tgctgctgat tatcaccaca ttcctaaaga tctagtagca cagctcagtg acatgtcagg
     3061 cttgagcaaa gaagaaaaat tggaccttat ttaccggcaa tggttacctg catggacgct
     3121 aacaccattt acccagcttg ctaacctgac gggaacacca tccttgtctt taccaaccca
     3181 tctgacgaaa agcggtctac ctcttggcat tttggtgaat agcggagctc ataacgatag
     3241 tctcctgtta caactgggac agctctttga aaaagcaaat cgtttccata tcctgacggc
     3301 tggcaaaaaa ggattgccag aaactcctgc gcatgagcat aacctctcaa ctcaatctga
     3361 aaacaaacaa ggcgttgcca ttccagtgac ttatcaaacc aagggattta ctactggacc
     3421 aaccaagggc cagaacggct tagtaaccct ccctcaaact ggtgatggtc agtcaaaagg
     3481 tgtgttgtta actagctaca tcagcctttt ccttggaacc ctcttcttag caggaagcct
     3541 ctggagcaat aaggtaaaag actaggctat tgtcgtcgga gatttaacct acctaaacat
     3601 tcactgctgc ttgccttacg ataagagtat attgtagtca atcaagactg aactttctta
     3661 gtgaaagttc agtcttttta cgtggccaaa agacagttgt tgcctgttct cattaggctt
     3721 agcaaccgct tttatgatat aatttgggta tgcatagaaa aacgattatt gatttcaaag
     3781 agctcgggca acgctatctt tttgatgagc cattagtaga attggtagcc aaaaccttag
     3841 atcaggtcgg cccagtcatt gaaaaagtac aacactacca acagctgggc tattacgtgg
     3901 tgggctatct cagttatgaa gcagctgctt tttttgacaa tgccttacaa acccataatg
     3961 acagactagg caacgagtac cttgcctatt ttacagtgca caaaacctgt caaaaaaaag
     4021 acctacctct tgattatgac agcattacta tccctaacca atgggtcagc gccactcaaa
     4081 aagaagccta tcaaaaagcc attgaaacca ttcaccatga gatgcgacag ggcaatactt
     4141 atcaggttaa ctataccatt caattaactc aggaactcaa tgcagctgac agcttcgcca
     4201 tttacaataa actcgtcgtt gaacaggctg ctggctacaa tgcctatatc gcccatgatg
     4261 agtttgccgt tatttcagct agtcctgagt tgttctttaa acaggaaggg aatcaactca
     4321 ccaccagacc tatgaagggc accaccaagc gcggggttaa cacctggctg gatcaacaag
     4381 aacatgattg gctccaagct gacgggaaaa atcgctctga aaacatgatg attgttgact
     4441 tgctccgcaa tgacatggga aaaatttgcc aaacaggcag tgtttgtgtc gataggctct
     4501 gtgaggtgga acaatactct accgtctggc aaatgacctc aaccattgtt ggtgacctca
     4561 aagcggactg tgacctgata gacattctca cagctctctt tccttgtggc tctatcacag
     4621 gggctcctaa agtctccacc atggcgatta tcacatctct ggagccaaac ccaaggggga
     4681 tttattgtgg aactgttggc atttgtctac ctgacggtcg ccgtttcttc aatgttccca
     4741 ttagaaccat ccagctcagt cataatcaag ctacttatgg tgtcggaggc ggtatcactt
     4801 ggcaaagcaa gtgggaagac gaatacgaag aagtccatca aaaaacagct tttctctatc
     4861 ggcacaaaca aatctttgac ctcaaaacaa ccgccaaggt ggaacaccaa aaaatagcct
     4921 tccttgagca acacctcaat cgccttaaag aagcagccac ttattttgct tacccttacg
     4981 atgagaaagc tttgcagaaa caactgtcaa cctatttgga aaataagaat aatgctgcct
     5041 accgtttgat gattcgttta tccaaagatg gaaagattag cctctctgat caacccttgg
     5101 aacctttgtc agccgatttt ctgacagctc aactctcttt acagaaaaag gacgtgacag
     5161 cttcgccttt tacctacttt aagaccagct accggcctca tattgagcaa aaatcttatg
     5221 aacagctatt ctataaccaa gcggggcaat tattagaaac gtccattggc aatctctttg
     5281 ttcagctggg tcagaccctc tacacaccac cagtggctgt ggggatttta ccaggacttt
     5341 ttcgccaaga gctgctagct actggtcaag ctcaggaaaa agaggtgaca ctagctgatt
     5401 taaaagaggc tagcgctatt tttggaggaa atgctgtccg tggcctctat cctctcaacc
     5461 ttgagcttac tcaccttgat gccctcttag ctaagagtca agcctaaact gccactcatc
     5521 ttttgttatt aaggaaccta tgatactctt aattgataat tacgattcat ttacctacaa
     5581 cctcgcccaa tatttaagtg aatttgacga gacgattgtc ttgtataacc aagacccaaa
     5641 cttatatgac atggccaaaa aggccgacgc gctagtcctc tcacctggtc ctggttggcc
     5701 caaggaagcc aaccaaatgc caaaactcat tcaagacttt taccaaacaa aacctatctt
     5761 aggagtgtgt ctgggacacc aagcgatcgc tgaaacatta gggggaacct tacgcttggc
     5821 caaacgcgtc atgcacggga gacaaagcac cattgaaacg caagaccctg ctagtctttt
     5881 tcgctccctg ccacaagaga tcaccgtcat gcgctaccat tccatcgttg tggatcagtt
     5941 accaaaaggt tttagcgtaa ctgctagaga ctgtgacgat caagaaatca tggcatttga
     6001 acaccacacc ctgccacttt ttgggctaca atttcaccca gaaagcatcg gaactcctga
     6061 tggcatgacc atgattgcta acttcatcgc agctattccc cgttaatccc atcccccaaa
     6121 agaaaggagg acagttacat gcctgatcat ttagcgctca gaatgcgccc caaaaccatt
     6181 tcagaggtca tcggacaaaa acaccttgtt ggcgaaggca aaatcatccg tcgcatggtg
     6241 gaagcaaata gactatcgtc catgatcctc tatggccctc caggaatcgg taaaacttcc
     6301 attgcttctg ctattgcagg tactaccaag tacgcctttc ggacctttaa tgccaccgtt
     6361 gatagcaaaa aacgtctcca agaaattgcg gaagaagcta aattttctgg tggcttggta
     6421 ttattactag acgagattca tcgccttgac aagacaaaac aagattttct tttaccttta
     6481 cttgagaatg gcaccattat catgattggc gcaaccactg agaacccctt cttttcagtg
     6541 acacccgcta tcagaagcag ggtccagatt tttgaattgg aaccactttc taacgaggat
     6601 attaaaacag ccattcagct agcaatttcc gacaaagaac ggggatttcc ttttttagtg
     6661 acaattgatg atgaggcgct agatttcatt gttaccgcca caaatggaga cctacgatct
     6721 gcttataatt ccttggatct agcagtcatg tctacttctc ctaatgaaga tagtagccgt
     6781 catattagtc tagagacaat ggaaaatagt ctgcagcgta gttatattac catggataaa
     6841 aacggggacg ggcattatga tgttttatct gccttacaaa aatccattag aggttctgat
     6901 gtcaatgcca gcctgcacta cgccgctcgt ttagtagaag ctggagactt gcctagttta
     6961 gcaagacgat tgaccattat tgcttacgaa gatattggct tagccaaccc tgacgcccaa
     7021 gttcataccg tcaccgcact agatgccgct caacgcattg gttttccaga agctcgtatt
     7081 cttatcgcta acgtggtcat tgatttggct ctatcaccta aatccaattc agcttattta
     7141 gctatggatg cagctttagc tgatttgaga acatcaggta acctccccat tccaaggcat
     7201 cttagagacg ggcattacgc tggcagcaag gacctaggca atgccaaaga ttacctctac
     7261 ccacacgcct accctgaaaa atgggtcaaa caacaatacc taccagataa attagtagga
     7321 catcattatt ttgaagccaa tgaaaccggt aaatacgaac gcgcacttgg ttcaaataaa
     7381 gagcgtattg ataagctctt agactgactg ctagttttaa aaatcgcaac cgatttcaaa
     7441 aatcgataat tttgcttgaa aaaattttaa aaagtggtat tataaaagta cagaaacatt
     7501 gctgtggcat acgaatccac atctaagtgt tgaccgacta tttctttgta ttttcgggaa
     7561 acaaagactc tttctagtct gcaagccgtt tcacgcggac gcaacttcca agaaagagcg
     7621 cgttacccac ctgcttatac tgcgcgggct caatacaaaa acgtggatca ccggtgccaa
     7681 tacagcattc ttgcctcctt agctcagttg gtagagcagt agactcttaa tctatgggtc
     7741 acaggttcga gccctgtagg gggtatacaa ctatacataa aaaagccttt gtttaaaggc
     7801 ttttttgatt gtttcataac taatcggctt aattaaaagc gtcaatccac ttttagtatc
     7861 atgtctcaat tttcatttga tagtcagcaa gtatatctac aaaattgtta atgattattt
     7921 cttttgaaag tgttatatta aaacataata aaataataac tcctgaaaag aggctattta
     7981 tgaaaaaaac aaaacttatt ttttctttga cttcaatatt cattgcaata atttctcgtc
     8041 ctgtgtttgg attagaagta gataataatt cccttctaag gaat
//
LOCUS       DAUCXI010000061         7894 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.061, whole genome shotgun sequence.
ACCESSION   DAUCXI010000061 DAUCXI010000000
VERSION     DAUCXI010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7894
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.061"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            145..894
                     /gene="truA"
                     /locus_tag="VGY43_001614"
     CDS             145..894
                     /gene="truA"
                     /locus_tag="VGY43_001614"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEQ4302777.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            884..1648
                     /locus_tag="VGY43_001615"
     CDS             884..1648
                     /locus_tag="VGY43_001615"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEQ4302778.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHVGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            1638..2108
                     /locus_tag="VGY43_001616"
     CDS             1638..2108
                     /locus_tag="VGY43_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEQ4302779.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWFGVVI
                     GSFIMIFWYFLGSLMLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRKKKR"
     gene            2122..2682
                     /locus_tag="VGY43_001617"
     CDS             2122..2682
                     /locus_tag="VGY43_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEQ4302780.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGVHLAVQGCEHVNRALVVERHVAESKQLEIVNVVPNL
                     HAGGSAQMAAFQLMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(2747..3592)
                     /locus_tag="VGY43_001618"
     CDS             complement(2747..3592)
                     /locus_tag="VGY43_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEQ4302781.1"
                     /translation="MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYL
                     FEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
                     GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIV
                     GKPNILGPQNNSNGQFTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYS
                     ITSKS"
     gene            3913..5196
                     /locus_tag="VGY43_001619"
     CDS             3913..5196
                     /locus_tag="VGY43_001619"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEQ4302782.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            5408..5983
                     /locus_tag="VGY43_001620"
     CDS             5408..5983
                     /locus_tag="VGY43_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEQ4302783.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            6240..7844
                     /locus_tag="VGY43_001621"
     CDS             6240..7844
                     /locus_tag="VGY43_001621"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEQ4302784.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
BASE COUNT         2582 a         1181 c         1712 g         2419 t
ORIGIN      
        1 agagagagtt tggaggaaat agctttctta tagcttttaa atcgttagta gcttagagta
       61 agcttcaata cgtctttcat ttgtttgggt acagtttgat taaaaatagt ttctcttacg
      121 tttaagaaat gttaaaatag taacatggta agatacaaag caacgatttc ctatgatggg
      181 actctttttt cgggttttca aagacaaaga catttacgta cagttcaaga agagattgaa
      241 aaaacacttt ataaattaaa taacggtaca aaaattataa ttcatggtgc aggacgtacg
      301 gatgcaggag tacatgctta tggacaggtg atccattttg atttgcctca agaacaagaa
      361 gttgaaaaat tacgatttgc tcttgataca cagactcctg aagatattga tgttgttaat
      421 atagaaaaag tggctgatga ttttcactgt cgttatcaga agcatttaaa aacttatgaa
      481 tttttagttg ataatggtcg acctaaaaat ccgatgatgc gacactatac cactcattac
      541 ccttatactc ttaatattaa acttatgcaa gaagctatta acggtctggt aggtacacac
      601 gattttactg gttttacagc agcaggaact tcggtacaaa ataaggtgcg aacgattacc
      661 aaagcaacgg tatctcggga tgaaaaaact gattttttgg tgtttacttt ttcaggaaat
      721 ggttttctct ataagcaggt gaggaatatg gtgggaactt tgctgaaaat tggtaatggt
      781 caaatgccag ttgaacaagt taaagtgatt ttgagctcca aaaatcgtca gctagctgga
      841 ccaacgatat ctggaaatgg gctttacttg aaggagattt gttatgaaaa ctgattatat
      901 cgtgactata tctgggaacg atattttaag tggaggtggc ctctatgctg atttagcgac
      961 ttacataagg tatgacctac aggcctttgt agcggtaact tgtttaacta ctagatctga
     1021 agagggcttt agtctatttc cggtagctaa agaaattttc cgtgatcagt tgaacagttt
     1081 tacgaacgct ccaatttctg ctattaaaat tggtttgtta cctaatgcgg aaatgtgtga
     1141 aatagttttg gattttataa aggggcatgt gggaatccca gtggttttag atcctgttct
     1201 agcatgtaaa gaaatagatg atgttaaaat agttcctcta agacaggaga ttttacaatt
     1261 attgccttat gtaactgttg ttactccaaa tttggtagag gctcagctat tatctcaaaa
     1321 agagattgtt tctttaaaag atatgcaaga agctgctaaa tatttttatc aacttggggc
     1381 aaaacaggtg gttatcaagg gtggtaatcg atttagtcag aaaaaggcta ttgatctttt
     1441 ttatgacggt aaagagattg ttaccttgga atgtcctgta cttgagaaaa ataatattgg
     1501 cgcaggctgt acttttgcat ctagtatcgc tagtcagtta gtaaagaaaa aaacgccact
     1561 agaagctgtg aaaaactcaa aagagttagt ctaccaagct attttacaat ctgatagata
     1621 cggagtaaaa caaagttatg caaaatagta agatacgaca aatgagttta acagggatat
     1681 tgacagcatt ggttgttgtt ttaggaagat ttgtcatgct acctactcca acaggttttt
     1741 taacgctgtt ggatgcagga atttatgctg tcagcttttc ctttggatca gctcaaggag
     1801 ctattgtggg agggttatca ggttttttaa tcgatttagt ggcaggatac cctcagtgga
     1861 tgtttcatag tttgattgct cacagtgtcc aagggtattt tgcgggatgg agaggacgca
     1921 agcgttggtt tggtgttgtg ataggttctt ttatcatgat tttttggtat tttttaggct
     1981 ctcttatgct tggttatggc ctttcgggat ctttagccgg tatttgggga aacgtcatgc
     2041 aaaatacatt aggacttttt gttggtttta ttatctttaa ggccatatta aggaaaaaaa
     2101 agagataagg agagtgagaa gttgttgaat aatttagaga aacaaacaag ggaaatcgtt
     2161 attgatgttg tagaacgctc tgctattcaa ccaggtaatc tttttgttct aggtctttca
     2221 tctagcgaaa ttttgggtag tagaattgga aaacaatcta gtctagaagt aggtcaaata
     2281 gttgttgaag ttgtgttaga tgagttaaat aagcgtggtg ttcatttggc tgtacaaggt
     2341 tgtgaacacg taaatcgtgc cttggtagta gagaggcatg tggcagaatc taagcagtta
     2401 gagattgtca atgtggttcc gaatcttcat gctggtggca gtgctcagat ggctgctttt
     2461 caacttatgt cagaccctgt cgaagtagaa gaagttattg cacacgctgg acttgatata
     2521 ggtgatactg ctataggaat gcatattaag cgtgttcaga tccctctgat tccttgtcaa
     2581 cgagagctag gaggtgctca tgtgacagct ttggctagtc gaccaaaatt aattggtgga
     2641 gctagggctg attacaatat ggatattatc cgtaaatcct aaaccctttt ttctggaata
     2701 aaacaattgg tgttttttct agaaaaaagg attttttaag attatattaa gattttgagg
     2761 tgatagaata gctgattgca gtcggtaatt gaatgccttc tttgagtaaa gcttcttgat
     2821 aaagtctata aaaagtatgg taaatcttaa attgttctcc attttctgtg aaaatagcaa
     2881 ttctaaaagt gaactgtcca ttagagttat tttgaggccc taaaatattt ggtttgccaa
     2941 cgatttgagg atggtttggc aattcctttt gattcacttc atcaatgatt cgagtgactt
     3001 ggctcaaatt aacagtggaa taaagaggaa tttcaattaa ggcacgcata ttaccacgag
     3061 atttgttgct gacaacggtg atgctacggt ttgggatgaa atgtagtgtt ccatcgaatc
     3121 cacgaatttg agtagttcta attccaacac caaagacact gccttctatg tcagagatag
     3181 taacgttatc tcctacttca aattgattct caaataagat aaaaaagcca ttgacaacgt
     3241 cagataaaaa tccttgtgca cctaacccga ttgctactcc agcaattcca gctcctgcta
     3301 gaagactaga gacaggtatg ccaaataagc taagtatcca ataaatgaga agaaaatata
     3361 ataagtagtt taaaatgttg tgagtgagct tagagagtgt ttttttgcga gcttcacttt
     3421 gtcttgaata agcaaacgat ttgttaatgg ttttttcaaa aagatagtta gtaacacgtt
     3481 ttaaaatagc aaaaaagagt aatagaataa tgagagacac tagcttttta aaaatcgtta
     3541 agccaatatt ttcgatatga gactgctcta ggtaatgtaa tataaatgtc atgagaaatc
     3601 ctttctttga tagtttatca aaaaaaaacc aatcttgaaa agagataaat taatatttta
     3661 accaaagtta tgataattgt tttatcataa agaatgccat agtcatccgt tgtgataatg
     3721 cttgaaaata gtcagttagt aagcgaaaaa gtctaacatt aacctttata aattgaaaat
     3781 aactgttagt agactaatga caggtagata ctcttaatag cgcgtttgat ttcacgcata
     3841 aaaagcttta aaaacgcttt aaattatgat aaaatgaact gtatcgaaat tattttaagg
     3901 agaaatgact taatgtctac atcatttgaa aacaaagcta caaatcgtgg cgtgattaca
     3961 tttacaatca gtcaagataa aataaaacca gctcttgata aagcttttaa taaaatcaaa
     4021 aaagacttaa atgcaccagg tttccgtaaa ggacacatgc ctcgtccagt cttcaaccaa
     4081 aaatttggtg aagaagttct ttatgaagat gctttgaata ttgtattgcc agaagcttat
     4141 gaagcagctg tgacggaact tggtcttgat gtggttgcac aaccaaaaat cgacgttgtg
     4201 tcaatggaaa aagggaaaga gtggacactt tctgctgaag ttgtgacaaa acctgaagtg
     4261 aaacttggtg attacaaaaa ccttgttgta gaagttgatg cttcaaaaga agtttcagat
     4321 gaagacgtgg atgctaaaat tgagcgcgaa cgtcaaaacc ttgcggaact cattattaaa
     4381 gacggtgaag cagctcaagg tgacactgtt gtgattgact ttgttggttc agttgatggt
     4441 gttgagtttg atggcggtaa aggagataac ttctctcttg aacttggttc aggacaattt
     4501 atcccaggtt ttgaagatca actagttggt gctaaagctg gcgatgaagt agaagttaat
     4561 gtcacattcc cagaatctta ccaagcagaa gatcttgcag gtaaagccgc taaatttatg
     4621 acaactattc acgaagtcaa aacaaaagaa gtacccgagc ttgatgatga gcttgcaaaa
     4681 gatattgatg aagatgttga cacacttgaa gacttaaaag taaaatatcg taaagaactt
     4741 gaagcagctc aagaaactgc ttatgatgat gctgttgaag gagctgcgat tgaattagca
     4801 gttgcaaatg ctgaaattgt tgatttaccc gaagaaatga ttcatgaaga agtcaaccgt
     4861 tcagtgaatg aatttatggg caacatgcaa cgtcaaggaa tctcacctga aatgtacttc
     4921 caattgactg gtacaactca agaagattta cataaccaat attcagctga agctgacaaa
     4981 cgtgttaaaa caaaccttgt tattgaagca attgctaaag cagaaggttt tgaagcaaca
     5041 gatagtgaaa ttgaacaaga aattaatgac cttgcaacag aatataacat gccagctgac
     5101 caagttcgtt ctcttctttc agcagatatg ttgaaacatg atattgcaat gaaaaaagca
     5161 gttgaagtga ttacaagcac agcaagcgtt aagtaatctt attaaggaac aaaacgtaca
     5221 agccggatta gaacgtcttt ctagtctggt ttttcttttt ctaaagataa ggaattagtt
     5281 aaacgttatt ttaatgaatt agctttaaag atttgtcaag aagaagtgat atgagttgat
     5341 aaaagttttg acgaattact ttttttagcg taaaatggta gagaatgata aaataaggag
     5401 aactgccttg aaattagacg tatttgcagg acaagaaaaa agcgagcttt ccatgattga
     5461 agtggcgcgt gccattttgg aagaacgcgg tcgcgacaat gagatgtact ttagcgattt
     5521 agtcaatgag attcaaaatt acttaggaaa atctgatgca ggtattcgtc atgcattacc
     5581 atttttctat actgacttaa atacggatgg ctcatttatt cctctaggtg aaaacaaatg
     5641 gggacttcgt tcgtggtatg ctatcgatga aattgatgaa gaaattatta ctctagaaga
     5701 agatgaagat ggcgcacaaa aacgtaagaa aaaacgcgtt aatgctttca tggatggaga
     5761 tgaagacgct attgattata gagatgatga tccagaagat gaagatttca cagaagaatc
     5821 agctgaggtt gaatatgatg aagaagatcc agatgatgaa aaatcagaag tggagtcata
     5881 tgattcagaa ttgaatgaaa ttatccctga agatgatttt gaagaagttg atatcaatga
     5941 agaagacgaa gaagatgaag aagatgaaga accagttctc taatgtcttt agttcagaaa
     6001 taaaaatgta attatcattt gacaaattgt ctattatagt ttatattatt attcgggcac
     6061 ctctttaaga ggtcaggcaa aagctctcta gttaataggg ggctattttt gttttctaga
     6121 ataatgccag tttgcctcta tatttagaaa actaaggtga tacctaacca atgtggaacc
     6181 aactaatagg gaattaacaa gaaagcaatg cttttattca gcttatataa aggagtacta
     6241 tgacgaaata catttttgta actggtggtg ttgtatcatc aattggcaaa ggaattgttg
     6301 cggcaagtct tggccgattg ttaaaaaatc gtggacttaa ggtgacgatt caaaaatttg
     6361 atccttatat taatattgat ccagggacga tgagccccta tcagcatgga gaagtatatg
     6421 tgacagatga cggtgctgaa accgacttgg atttgggtca ctatgaacgt tttattgata
     6481 tcaatcttaa taaatattcc aatgttacaa caggtaaaat ttatagtgaa gtccttcgta
     6541 aagaacgtaa aggtgagtac cttggagcga ctgttcaggt gattcctcat atcacagatg
     6601 cccttaaaga aaaaatcaaa cgcgcagctt caacaacgga ctctgatgta attattactg
     6661 aggtcggggg gactgttggc gatattgaaa gtttaccgtt cttagaagct cttcgtcaga
     6721 tgaaagctga tgttggttct gaaaatgtga tgtatattca caccaccttg ttgccatatt
     6781 taaaggcagc gggtgaaatg aaaactaagc caacgcaaca ttccgttaaa gaattgcgtg
     6841 gtttagggat tcaaccgaat atgttggtta ttcgtacgga agagccagtt gagcagggga
     6901 ttaaaaataa attggctcag ttctgtgatg tgaattcaga agctgttatc gagtcacgtg
     6961 atgtagaaca cttgtatcaa attccattga acttgcaagc tcaatcaatg gatcagattg
     7021 tttgtgatca tttgaaattg aatgcgccac aagctgatat gaccgagtgg tcagctatgg
     7081 ttgacaaggt gatgaattta agaaaaacaa caaaaattgc cttggttggt aaatatgtgg
     7141 aattgccaga tgcctactta tctgttgtgg aagccttgaa acattctggt tatgccaatg
     7201 ataccgcaat tgacctaaaa tgggtcaatg ctaacgatgt gacggtggat aatgcagctg
     7261 acttgttggg agatgcggat gggattattg taccaggtgg ttttggtcaa cgtggtacag
     7321 aaggcaagat ccaagcgatt cgctatgccc gcgaaaatga tgtgccaatg cttggtatct
     7381 gtcttggcat gcagttgact tgtgttgaat ttgcccgcca tgtcctcaat atggaaggtg
     7441 caaactcttt tgaattagag ccaagtacta aataccccat cattgatatc atgcgtgatc
     7501 aaattgatat tgaagatatg ggaggtacgc ttcgtctggg attgtaccca tgtaaattga
     7561 aaccaggttc aaaagcagca atggcttaca ataatcaaga ggtggtgcaa cgtcgtcatc
     7621 gtcaccgtta tgagttcaac aacaaattcc gtccagaatt tgaagcagct ggttttgttt
     7681 tctcaggggt atcacctgac aatcgcttag ttgaaattgt agaattgaaa gagaaaaaat
     7741 tctttgtagc agctcaatac cacccagaat tgcaaagccg tccaaatcgt cctgaggagc
     7801 tatacaccgc ttttgttaca gctgctatta aaaatagcaa ttagtggttt taagggtaag
     7861 tttgtggcat tctacttggc tggcagatac tgat
//
LOCUS       DAUCXI010000062         7870 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.062, whole genome shotgun sequence.
ACCESSION   DAUCXI010000062 DAUCXI010000000
VERSION     DAUCXI010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7870
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.062"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(97..1293)
                     /locus_tag="VGY43_001622"
     CDS             complement(97..1293)
                     /locus_tag="VGY43_001622"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEQ4302785.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            complement(1830..4208)
                     /locus_tag="VGY43_001623"
     CDS             complement(1830..4208)
                     /locus_tag="VGY43_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEQ4302786.1"
                     /translation="MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSCKGMTS
                     NKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQRAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSRLVSTATANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKDSILVDHDGHLHPISFADLRQGGWAHVADQYDPAKKAEKPAETHHTP
                     ELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIG
                     KDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNKM
                     KDWLATVIKLDLGSRKDPLQRKGLSLLPNLETLGLGFTPIKDISPVLQFKKLKQLLMT
                     KTGVTDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLP
                     NLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVD
                     LATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEA
                     EGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPN
                     KTVTNIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAK
                     ESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            4412..5353
                     /gene="birA"
                     /locus_tag="VGY43_001624"
     CDS             4412..5353
                     /gene="birA"
                     /locus_tag="VGY43_001624"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HEQ4302787.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEK
                     RAIAIDLTDQGYLIVQFENGDLQTLRSGEISLSSWEN"
     gene            complement(5328..5531)
                     /locus_tag="VGY43_001625"
     CDS             complement(5328..5531)
                     /locus_tag="VGY43_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEQ4302788.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVHTINQLTKTILKTANSPKKKD"
     gene            complement(5626..7296)
                     /gene="dnaX"
                     /locus_tag="VGY43_001626"
     CDS             complement(5626..7296)
                     /gene="dnaX"
                     /locus_tag="VGY43_001626"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEQ4302789.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVTIAIAEEITGSISILALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAQKEQILSQANLSGELISEIETLKNELAQLKQQLSQLQSRPD
                     SLARSDKTKPKTTSYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQD
                     RALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVP
                     RTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD"
     gene            complement(7296..7793)
                     /locus_tag="VGY43_001627"
     CDS             complement(7296..7793)
                     /locus_tag="VGY43_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEQ4302790.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPN
                     SVFAGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNM
                     FGVKN"
BASE COUNT         2302 a         1657 c         1441 g         2470 t
ORIGIN      
        1 cttaattttt aatcatccct tttaaaggct tatttaataa caaaaaagca gagtaagatt
       61 ttttcactca ctctactttt ttaataaagt tgtcgtttat aatactgttt ttacagcttc
      121 tactaaagca tcaaccttat ttaaacgctc ccatggcaaa tcaatatctg ttctccccat
      181 gtgaccatag gcagctgttt gtttgtaaat cgggcgtttt aaatcaagca tttgaataat
      241 gcctgctggc cgtaaatcaa agacttgacg aacagcagct tctaaaacag cttcaggaac
      301 cgttgaggtt ccaaatgtat ccacgcgaac agacacaggc tgagccaccc caatcgcata
      361 agctagttgg acttcagctt tcgtcgcaag acctgctgcc acaaggtttt tagcaatata
      421 acgagcagcg taagaagccg aacggtccac ttttgtcgca tcttttcctg aaaaagcacc
      481 gccaccatga cgtgaatagc ctccataggt atccacaata atcttacgtc cggtcaatcc
      541 agagtctcct tgcggacctc caataacaaa acgtcctgtt ggattaatga agaactttgt
      601 gtcatcatct aaataatctg ctggaattac agccttgatc actttttcaa tcacatcctg
      661 acgaatttgg tcattagtag cttctggatc atgctgagta gaaataacga ctgtatccac
      721 acgaacaggt ttatcgtgtt catcgtactc aactgtcact tgagatttag catctggacg
      781 tagataacta atctcacctg acttacgtaa ttccgccaag cgacgcacta attggtgaga
      841 taaggaaatt ggtaaaggca tcaattctgg tgtttcattg atggcaaaac caaacatgag
      901 cccttggtca cccgctccaa tatggctaag gtcatcagta tcaccttctc tgctttcgag
      961 agcttcatta accccctgag cgatatctcc agattgttct acaagtgatg gatgtactcc
     1021 cactgattct gctgaaaagc catattctgc ttctgtataa ccaatttctg caatggtgtc
     1081 gcggaccaca cggttaatat caatgtatgc tgttgttgag atttctccaa aaacatgaac
     1141 agaacctgtg taaacacaag tttctgcagc cacatgggct tctggatctt ctgctaaaat
     1201 ggcatctaaa atagcatctg aaatttggtc tgcaatctta tctggatgcc cttcagatac
     1261 ggactcagac gtgaaaagtt tacgttctga cataaaaatg tcccccctaa tatgttgatt
     1321 cttccttttt cagtcacatt gaccacaaag caagaagttg cctacccctt tcttcctagc
     1381 tgattgagca agtcaagtgg ccaaaaccaa cttagctaat cagttacggt tttactagta
     1441 aggcaactag ctagtccacc tagtggctag cgtccattaa ccagacaaag aatgtctgac
     1501 aatagcgttg agttacaaag aatccggtct ccttgttgag aggatgtcac cacaaaataa
     1561 gccttagacg aagtaattta gctaaaggga gaacgactgt tccccaaatg aagtcaacaa
     1621 cgtctcaaaa acatttcgtt caacagaccg tcttatcggg actcaataac aatctattat
     1681 aacatgtttt agccatttag gtgccattct tttcactcat tatcctattt atttcaaaaa
     1741 aacctcaagg ttattcttga ggttctcttg atagtcaaca atggtgtcat taggacgatt
     1801 cagttggatc gggttattct tagattagtt tagtcagcat ggttttgctc atctttagct
     1861 tcattttcat cctcatgttc atggtcgtga tcatctttgt ctctgtgctc gtgagcatga
     1921 ccttcttcat cttcataggt atgattatgg ttgtagtcat gtgattccga tgcttcttga
     1981 gcactttctt tcgccttagt agccatagct gctttttctt cagctgttcc attacctacc
     2041 atagaacctt cgtaaaccgc tgggaagttt ttcgcaatgg cttctggaat atgttgctcg
     2101 ttcaatttaa ggtctgccaa tgggatattg ttatgactaa tatcaatgtt agtaactgtc
     2161 ttattgggtt tagataagtt gacatttgtt aattggtttt tagacacgct taaaatgtca
     2221 agtgctgtaa aattattaac accttctaga gaagtcaact ggttgcctgt cacatccaag
     2281 aaagtaagtg acccttgctt gtctttaagc acaagcgatt taatttggtt accttctgct
     2341 tctactctga caatgacgct acttgcttca ataccttcaa gagattgcaa ttgcgcacgg
     2401 ttaatagata ggctagatag attaggatta tttttcaaga aatccaaatg agaaaccttg
     2461 gtatcattga ccattaacgt ttctaatttg ggtgcttgaa gtgttgctaa gtcaacatca
     2521 gcatttcttg ataaatcaac aaccgtcaat gattctttat gagaaacagg gcttaaatct
     2581 gtaatctgat tattatcaat gtgcaattct tgcaattgat gtaacgatgc cagtgggctt
     2641 aaatcagaaa tcttattatt actcaatacg aggaatttga gatttggtaa ttgaccaagc
     2701 ggcctaatat cttcaatacc attatcagca gccgctacta gagttaagtt tttatatttg
     2761 ctcaagaaac taatatcttt gagattgttt tgtgaaatat caatgccttc taactgtggc
     2821 atattatcca aaaatctata atcagtcacc cctgtttttg tcattaacaa ctgtttcaat
     2881 tttttaaatt gcaaaacagg tgagatatct ttgattggtg taaagccaag tcctaaagtt
     2941 tctaagttgg gtaacagtga aagtccttta cgttgcaaag gatctttacg gctgcccaag
     3001 tcaagtttga taaccgttgc taaccagtct ttcatcttat tcggatcttt ttcatttgat
     3061 gggaatgggg ttggagcatc gtgagtgcga acgatatcca aaatcacttc ttcatcaaac
     3121 cctaaggcac gcaaggtatc cattccaacc ttatgttttt ccaattcacg ggcatgctca
     3181 atagcatgtg gatctggaat gtcttttccg atttcaatat cagataacat caatacgtgt
     3241 gcgtggtcat ggtgagggta ttccaaacca agtttaccgt cttgtgtttc cacacgttta
     3301 atagttgatg gatcaatccc caatttttct gccaaataag ctaatttttc ttggtattcc
     3361 ttttcacgtt cagatagctc tggtgtgtga tgggtttctg ctggcttttc tgctttttta
     3421 gcgggatcgt attgatctgc cacatgtgcc cagccaccct gacgaaggtc cgcaaaagaa
     3481 ataggatgta agtgaccatc gtggtccact aaaatactgt cttttgttac cccaacaata
     3541 ccttgaccgt taaattgaaa accatctgag gttgggaaat gcaagcctgg aataccatta
     3601 gctgtagctg ttgaaacaag tctactggtt tgtggcaagc gagtagcaac ctgtttagct
     3661 tgtgcctgtg tctgacctga taagcttgac ttcaaaatat aatggaagtg atcatcgtgg
     3721 cgaaccgtgt agcctaaagc atcttcagcc acaatatccg ctgggttaaa ttcataatgg
     3781 tgatgaggat ctgctacttt agaagtccct tgactagctg ctcgctgagc aacagctggc
     3841 ttagctaaac ttgctccttt tggaataagg tattcaaatg gacttccctt taaatcggca
     3901 taaaaaataa aatgcgaatg accatcatgg tcaacaacga ttccctgatc tgtttttgat
     3961 aagatttttg agtctttggt taaaataaac ccatcatctg taggaaaatc gacacccgcc
     4021 acacctttgt gagtcttgtt tgtctttttg ctttttttaa tcggtttaat tttgtttgac
     4081 gtcattccct tacatgattg tttcgtttta atgggatatg taccattacc tcgtgattga
     4141 caagctatca aagtcaactg agatgataac aatagaccaa ctaaaataat aacttttttc
     4201 gttttcattc aaccctcctt tttatttaac tggttaagta tatcacatca cttgtttttc
     4261 ctcaagctct ttttaggata actattagtt gttgacgagt tggagctctg aagcttcaac
     4321 aaacaatagt ttctgttgtt agtagcatta cacaaaaaaa ctaacttttc ttttcctttg
     4381 aaaataagat cttttataat atactataca tatgaaaaca tcagaaaaaa tttatcaatt
     4441 actgtcacaa accgatgact tcgtcagtgg ggaatatcta gcagatcaac tcagtatctc
     4501 tcgtacatcc gtttggaaat ccatcaaaag tctcgaaaat caggggattc aaattgattc
     4561 tttaaaacac aagggctacc gcatggtaca aggtgatatt ttattaccca aaaccattag
     4621 ccaagggctt gggatgccag tcacctatac ccctcatagc caatctaccc aattagatgc
     4681 caaacaagga atcgaagctc ataacagcgc tccaaggctt tacctagctc ctagccaaga
     4741 agctgccaaa ggacgcctcg atcggcaatt tttttcagct agcaccggtg gtatttacat
     4801 gtccatgtac ctaaaaccca atgtccctta tgctgatatg cctccttata cgatgatggt
     4861 tgcttccagt attgtcaaag ctatctcgcg attaacaggc attgatacag aaatcaaatg
     4921 ggtaaacgac atctatctag gtaaccataa agttgcaggg attctgacag aagccattac
     4981 ttctgttgaa actggtttaa tcaccgatgt cattattggg gttggtctca acttttttgt
     5041 caccgacttc ccagaagcga ttgctcaaaa ggcaggttct ctctttaccg aaaaaccgac
     5101 tatcacgcgt aatgacctta tcattgacat ctggaaatta ttcttatcta ttcctgtcaa
     5161 ggaccatgtc aaagtttaca aagaaaaatc acttgttctt aataaacaag tgacctttat
     5221 agaaaatagt caagaaaaac gtgctatcgc gattgatctc acagatcaag gatacctcat
     5281 tgtacagttt gaaaatggtg accttcaaac cttgcgaagc ggtgaaatca gtctttcttc
     5341 ttgggagaat tagccgtttt taaaatggtt ttagtcaatt ggttaatggt atgcactctt
     5401 cttaaatctc taaagagcaa caagccccaa aataaggcga agagataatt tccagagagc
     5461 aacaggtcat taaaaaaata ggtttcaaag gcacatacaa aggccataaa aagaaattgt
     5521 cgaatagtca tagctttatt ataacaaaaa aatactgtac tatgaagaaa agtaacgaga
     5581 taaaacgtgg gtaagggcaa aaccttaccc ttatgtattt cagttttagt cgtcaatagt
     5641 atttatttta tcgagcaaaa aatcaaaccc ttctggaata tcaagcgcta cttcttgttc
     5701 ttcttgaaca ctgtcttttt gcgatttcat ttgctgagca aattccttac gaatatgctg
     5761 aaaatctgtc cttggtactg ccagaatatt gggagaaaaa ccagcagctt tactcataat
     5821 gttaccaaac atatcattaa gattatttcg gctcatgact tgttctgcat taaaggcagc
     5881 ctcgaaagcc aaaatcgcat tctcactatt tgctaagaca ggctcagagc ccatcaataa
     5941 ggctctgtct tgggcagaaa tgttatctag aatttcattc caagcatttt ttagagcatc
     6001 tagatattgt cgagattgtt ggctatttcg aaccgtttct tccatgattt tcaaaatggt
     6061 aacccgatca accctgtagc ttgtggtttt aggtttcgtt ttatcagatc ttgccagtga
     6121 atcaggacgc gattggagct gcgacaattg ttgtttaagt tgtgccaact catttttgag
     6181 cgtttcaatc tctgagatta actctcctga caagtttgct tgggacaaaa tctgctcttt
     6241 ctgagctaat tggatggtca tcatttcggc ataaatccga ggatgggttc cctttttgat
     6301 ttcagggaga tgactagtaa caactgttat catttggaat atacgatcta tcgagagaga
     6361 caaattggta tcaaaaacag ctgactgacg ttgattgtcg ccgccagctt taaccaccaa
     6421 taaatcacgc agataggtca ataaatctgt cgcaaagcgg ctcatgctct tcccactatc
     6481 ataaatggtc tctaaggctg ccagagcttg cgtagcctgt tcttgggaga catatcgaac
     6541 atagtcaccc agagcaagta tggaaataga acctgtaatt tcttcggcaa ttgcaatggt
     6601 gacctgatta tctggtgaca agctcaaagc ctgatctaaa atagataaag catcacgcat
     6661 gcctccttct gctcgccttg caatgagatt taaagcatcc acctcatagg caataccttc
     6721 tttgtccaaa acccaggcta aatgctctcg aatagctttt tgcttaatag ctttgaattc
     6781 aaagcgttgc acacgagata aaatagtggc tggaatttta tgcaattccg ttgttgccaa
     6841 gataaagaca acattttctg tcggttcttc caaagttttc aaaagcgcat taaaagcccc
     6901 tgttgataac atgtgaacct catcaataat ataaaccttg taagtcgcac gacttggcgc
     6961 ataggttgat ttgtctcgaa tgtcacgaat ttcatcaaca ccattattcg aggcagcatc
     7021 aatttcaatc acatcttcta agcttccatt cgtgatatct cggcaaatat cgcattgatt
     7081 acagggttca ccatcgactt ggttaggaca attcatggcc tttgcaaaaa tctttgccgc
     7141 acttgttttc ccagtccctc taggacctga aaaaagataa gcatggctaa tcttgccaga
     7201 ttcaactgcc tgctttaaag ttgtggaaat aaccgattgt cccaccattt cgtcaaacgt
     7261 ttggctccgg tatttccgat aaagagcttg atacatcagt ttttaactcc aaacatgtta
     7321 aaggtaaacg tggtcttttc aagaaatagg tccacaaagg cctctaagta ttcttgatca
     7381 acctcatcat aatcagctac aaggctagaa tccaagtcca gcaccccaat caaatggcct
     7441 tctttcacca taggcacaac aatttcactc atggctgccg catcacagga aatatagttg
     7501 gcatgctgct tcacatcatt tataataatg gttcgacgag actgagctga ttcgccacaa
     7561 acacctttac caagcttgat atggacgcaa gaaaccctac cttgaaaagg gccaagaatt
     7621 aattcctgcc catcaaaaag gtaaaatccc gcaaaaacag aattgggtag tgtcatgttt
     7681 aacagggcgc tggcatttga caaattagcc aaagcatttg attcattcgc aaacagctct
     7741 tttgcctgtg ctatcattag ttggtattgc tcaatttttt tagacttatt catacctttt
     7801 attatagcat atctgggtct attcgagtat tttttacgac tatctttcgc ttcagtcagt
     7861 ttttaaaatg
//
LOCUS       DAUCXI010000063         7751 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.063, whole genome shotgun sequence.
ACCESSION   DAUCXI010000063 DAUCXI010000000
VERSION     DAUCXI010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7751
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.063"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            554..943
                     /locus_tag="VGY43_001628"
     CDS             554..943
                     /locus_tag="VGY43_001628"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEQ4302791.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFAPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            1037..2089
                     /locus_tag="VGY43_001629"
     CDS             1037..2089
                     /locus_tag="VGY43_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEQ4302792.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGAAGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIAAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            2228..3760
                     /locus_tag="VGY43_001630"
     CDS             2228..3760
                     /locus_tag="VGY43_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302793.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVLPENTNKQELGILMAGGSIYKEEG
                     HV"
     gene            3753..4817
                     /locus_tag="VGY43_001631"
     CDS             3753..4817
                     /locus_tag="VGY43_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302794.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            4819..5775
                     /locus_tag="VGY43_001632"
     CDS             4819..5775
                     /locus_tag="VGY43_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302795.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(5988..7706)
                     /locus_tag="VGY43_001633"
     CDS             complement(5988..7706)
                     /locus_tag="VGY43_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEQ4302796.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKGEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDESKSAGLIQVIGEDVDMEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVDADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMNKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
BASE COUNT         2312 a         1293 c         1600 g         2546 t
ORIGIN      
        1 tctactcgag taaccttttt taatgtattt taactgaaaa aggctttcat aattttaaaa
       61 aaatgttaaa ataggtgtat aacaactgat taccaagaga ttattatcat tatcttctaa
      121 ggtgtcattg ttatggtgac aatcaaccat acgctactaa agataggtag cgttcgatca
      181 caggttgatc aagtgattga aaaatcaata tttataattt tacaaatatc tgtatcaatc
      241 catgttgaat agtctatgct tctaaggtgt cgacgttaat gtactgacgg gaccgttata
      301 gtctttcttt ttggagaaac gtcggatgcc agtgaactag ttgaagttaa agatgttaat
      361 tcaaacagtg ctgaagagat tgatatcgtt ttgaacggtc gtttacttca aagcaaagaa
      421 attaccagtc tatcggagat gatataagtg ttaaagttag atcacgttaa ttatctatca
      481 agtcgggtgc atatttcgtt aaagtatcca caggggtttc aatagatgta gctattatga
      541 aaggtgatgt tcaatgggga ctactgattt agttagttgt gctgtacaag ctagtgagta
      601 tgcttatgtc ccttactctc attttccagt aggagcagct ttaaaaacaa aagatggaac
      661 gatctatact ggctgtaata ttgaaaatgt tagttttggt ctgacaaatt gtggagagcg
      721 aacagctata tttaaagcca tatctgatgg tcataaagaa ttggttgaaa ttgctattta
      781 tggagaaact atgcaacctg tatctccttg tggggcttgt cgtcaggtaa tggcagaatt
      841 ttttgctcct tcttctttag tcactttaat tgctaaaaat ggtcaaactg ttgaaatgac
      901 tgttggagat ttactcccct attcttttac agatttaata taatctgctt taatttctgt
      961 tatctagccg tcttggcttt atatttactt tcagcaactt atttgctaga aatctttttt
     1021 aggagggttc atattcatga acaagaaatt tattggtctt ggtttagcgt cagtggctgt
     1081 gctgagttta gctgcttgtg gtaatcgtgg tgcttctaaa ggtggggcag caggaaaaac
     1141 tgatttaaaa gtcgcaatgg ttaccgatac tggtggtgta gatgacaaat cattcaacca
     1201 atcagcatgg gaaggcctgc aatcttgggg taaagaaatg ggccttcaaa aaggaacagg
     1261 tttcgattat tttcaatcta caagtgaatc tgagtatgca actaatcttg atacagcagt
     1321 ttcaggaggg tatcaactga tttatggtat cggctttgca ttgaaagatg ctattgctaa
     1381 agcagctgga gataatgaag gagttaagtt tgttattatc gatgatatta tcgaaggaaa
     1441 agataatgta gccagtgtta cctttgctga ccatgaagct gcttatcttg caggaattgc
     1501 agctgcaaaa acaacaaaaa caaaaacagt tggtttcgtg ggcggtatgg aaggaactgt
     1561 cataactcga tttgaaaaag gttttgaagc aggagttaag tctgttgacg atacaatcca
     1621 agttaaagtt gattatgctg gatcatttgg tgacgctgca aaaggaaaaa caatcgcagc
     1681 agctcagtat gcagcaggtg ctgatgttat ttaccaggca gcaggaggca ctggagcagg
     1741 tgtatttaat gaagcaaaag ctattaatga aaaacgtagt gaagctgata aagtttgggt
     1801 tattggtgtt gaccgtgatc aaaaagacga aggaaaatac acttctaaag atggcaaaga
     1861 agcaaacttt gtacttgcat catcaatcaa agaagttggt aaagctgttc agttaatcaa
     1921 caagcaagta gcagataaaa aattccctgg aggaaaaaca actgtctatg gtctaaaaga
     1981 tggcggtgtt gaaatcgcaa ctacaaatgt ttcaaaagaa gctgttaaag ctattaaaga
     2041 agcgaaagca aaaattaaat ctggtgacat taaagttcct gaaaaatagt gtttaagaac
     2101 aagaagcgcg acctttgtcg gtcgctcttt ttaaactgag ataattttta tctcagtaaa
     2161 gtttgtgata ggtgatagat cataggcttt actgaaataa aagattgcat tgaaaggaaa
     2221 tgatcctatg acacagcatg tcattgaaat gagagaaatc acgaaaaaat ttggtgattt
     2281 tgttgcaaat gaccacatta acttaaatgt cagaaaaggt gagattcatg ccttattggg
     2341 tgaaaatggg gcaggtaaat caactttgat gaatatgcta gctggtctct tagagcctac
     2401 tagtggagaa attgtcatta atgacaagcc agttcaaatt gattcgccat ctaaatcagc
     2461 taagcttggt atcggaatgg tacatcaaca tttcatgtta gtagaagcct tcacggttgc
     2521 tgagaatatt attttaggaa atgaagtagt aaaaaatggg tgcttagatc ttaaccaagc
     2581 atcgaaagat attaaggtac tatccgaaaa atatggcctt gcaatcaatc catcagctaa
     2641 agtttctgat atttcagtag gagcacaaca acgtgttgag attttgaaaa ccttgtatcg
     2701 tggtgcagat attcttatct ttgatgagcc aactgccgtt ttaacacctg cagaaattaa
     2761 agaattgatg actatcatga agaatctcgt gaaagaagga aaatcaatta ttttaattac
     2821 ccataaactg gacgagattc gtgctgtcgc cgaccgtgtc acagttattc gtcgtggtaa
     2881 gagtatcgaa acagttgatg tggcaggagc aacttcacaa gatttagctg agatgatggt
     2941 gggacgctcg gtttccttta caactagcaa aaaagctgct gaaccaaaag atgtggtctt
     3001 atccatcaaa aatcttgaag tagatgaaaa tagagggatt ccagcagtta aggggctatc
     3061 tctagatgtc cgagctggtg aaattgtagg gattgctgga attgacggaa atggtcaatc
     3121 tgagttaatt caagctatta caggtttacg taaagtcaaa tctggaagta tcatgattaa
     3181 aaacaatgaa gtcactcatt tgtcttcacg caaaattact gagttatcag tgggtcacgt
     3241 gccagaagat cgtcatcgag atggtttgat actagatctt tctttagctg aaaatacagc
     3301 cttacaaacc tattacaaac aacctctaag tcaaaatgga atcttaaatt atactaaaat
     3361 taatgactat gctcgtcaat taatgaaaga atttgatgtt cgcggagcca atgagctagt
     3421 accagctaga ggattttctg gtggtaacca acaaaaggcc attattgctc gtgaagtgga
     3481 ccgtgatcca gatttactta ttgttagcca accaacacgt ggtcttgacg taggagctat
     3541 tgaatatatc cataagcgtt tgattaaaga acgtgataaa ggtaaagctg tcctcgttgt
     3601 tagttttgaa cttgatgaaa tattgaattt atctgatcga attgctgtta ttcatgatgg
     3661 taaaattcaa ggtatcgtat tgccagaaaa taccaataaa caagaattgg gtattttaat
     3721 ggcaggtggt tcaatttata aggaggaagg tcatgtctaa aaatgcgcaa aaaattgctg
     3781 taccattgat ttctgtcttg ctaggatttt tacttggcgc tattattatg gttatctttg
     3841 gttatgatcc tatctggggg tatgaaggtt tattccaaat tgcctttggt agtgttaaaa
     3901 atattggaga aatattccgt tcaatggggc cattgatttt aatagcgctt ggctttactg
     3961 ttgctagccg tgcaggcttc tttaacgttg gtttgtctgg acaggcttta gctggatgga
     4021 tttcagcagg ttggtttgca ctcttaaatc cagatatgcc tcgtccatta ttgattctta
     4081 tgacagctct tatcggaatg gttgctggtg gtattgctgg agctattcca gggatacttc
     4141 gtgcttatct tggtacaagt gaagttatcg ttacgattat gatgaactac atcattttat
     4201 atgtcggaaa tgctattgtt caacgtggtt atcctgagag tgtcaaacaa agtattgatt
     4261 caactattca agttagtgat aatgctagtt atcaaacgca ttggttatca gccctaacta
     4321 ataactctcg tattaatatt ggtattttct ttgccattat tgccattgcc ctaatctggt
     4381 tcttgcttaa caaaactact ttaggttttg agattcgttc agttggtctc aacccacatg
     4441 cttcagaata cgcagggatg tcatcaaaac gtactatcat tttatcaatg attatctctg
     4501 gagctcttgc aggtcttgga ggagtagttg aaggtctagg aacctttgaa aatgtttttg
     4561 tacaaggatc ttctttagca gttggttttg acggtatggc agttagctta ttagcagcaa
     4621 attcaccgct tggaatattt ttctcatcat tcctatttgg tgtcttaaat attggtgctc
     4681 caggaatgaa tattgcaggc attccaccag aacttgttaa agtagtaact gcatcaatca
     4741 ttttctttgt tggttcacat tacctcattg aacgttacat tattcgccct aaaaaattag
     4801 tgaaaggtgg taaataagat gagtttagta acaatttttg ccttattggt gtcatctatg
     4861 cttatttatg caacaccact cattttcaca agtattggag gaactttctc agagcgctca
     4921 ggcgttgtta atgttggttt agaaggtatc atggtcatgg gagcgttctc tgggattgtt
     4981 ttcaacttag agtttgctga aacatttgga aaagcaacgc cttggatagc cgttttagtc
     5041 ggtggtattg ttggtttgat tttttctttg attcacgctg tagcaaccat caactttcga
     5101 gctgaccaca ttgtcagtgg tacagtgttg aacttgttag caccttcttt tgctgtcttc
     5161 ttggttaaag ctatgtacgg taagggacaa acagacaaca ttcaacaatc ttttgggaag
     5221 tttgatttcc caggtttatc acaaattcct gtgattggtg atattttctt taaaaatact
     5281 agccttattg gttacttcgc cattgctttt tcgttctttg cttggttttt gctttataaa
     5341 accaggtttg gtctgcgttt acgatcagtt ggggaacacc ctcaggcagc tgacacactt
     5401 ggtattaacg tctatttgat gaaatactat ggtgtgatga tctcaggttt tcttggtgga
     5461 ataggtggag ctgtttatgc tcagtcaatc tccgttaact ttgctgtaac aactatctta
     5521 ggtcctggat ttattgcttt ggcagctatg atctttggta aatggaatcc agttggcgcc
     5581 atgctatcta gtcttttctt tggcttatcg caaagtttag ccgttattgg tgctcaatta
     5641 ccattactag aaaagattcc aacggtttac ttacagattg caccttatat ggtaacgatt
     5701 attattttag ctgctttctt tggtcaagca gttgcaccaa aagctgatgg aatcaactat
     5761 attaaatcta aataacgtta tattagtaag cctcttagtg aggtttaaca gcactcctaa
     5821 agcaagatag ttaggtctag ctttaagggt gcttttttgg gacttaccgc aagtttggat
     5881 tgccagtcac catcacaata gaagcaagaa tagactaaaa agaactaagt cagcggctta
     5941 gttctttttg cttgtctttc gtttttactg atagctctta agttgtttta gccaacaaag
     6001 gtattgattt ctgtttcaat gttagcaatt ttttcttgag cgatgtcaag agtatcacct
     6061 attgtggcaa tatagaactt gatttttggt tcagttcctg aagggcgaac tgcaatccat
     6121 gaatcatcag ctaacgtgta cttcaaaaca ttacttggag gagttgttaa gttagatatt
     6181 gttccatcat ttttagtagc ggtttgtttt tggaaatctt ctaataatac aatatcagta
     6241 ttgttaaatt gttttggacc attttcacgg aatttgttca taatcttctt aatttcagca
     6301 gctccatcca cacctgaaag tgttactgaa atcgtttttt cagcaaaata gccatattct
     6361 ttgtaaattt catcaatacc atctgcaagt gttaaaccac gcgaacggta ataagctgcg
     6421 atctcagcaa ccaaaagaac tgcttgaata gcgtctttat cacggacaaa tggtttaata
     6481 agatatccga agctttcttc aaaaccaaac atataggtgt ggttatgttt ttcttcaaac
     6541 tcttgaattt tctcagcgat gaatttgaat ccagttaaaa cgttaaacat tgtagcgcca
     6601 taactttcgg caatttttgt tactaattct gttgatacga ttgatttagc gagagcagca
     6661 ttttctggaa gtgttcctgc tgttttatga gcttccagga tgtatttcgc aataatcgct
     6721 ccaatttgat ttccagaaag atttttataa gaaccatctg gttggcgaat ttcaacgcct
     6781 aggcggtctg catcaggatc ggtagctact aagacatctg catcaacttc tcgtccgagt
     6841 tcttcagcaa gagcaaaggc agcttggctt tcagggttag gcgatttaac agtagaaaag
     6901 tctggatctg ccttagcttg tgattctact acaacaacag attcaaaacc ggcttgagca
     6961 agggcacggc gtgtcaacat ctcaccagtt ccgtggagag gagtatagac aattttcatg
     7021 tcttttccaa agttattgat taaatcttga ttgatattaa catctttaac ctctctaaga
     7081 tattccatat caacatcttc accgataact tgaataagac ctgctgattt gctttcatct
     7141 aaatcagcaa gttcaactgc aaatggattt tcaatagcac ggataaagtc tgttagtgca
     7201 tcagcatcag ctggtggtag ttgacctccg tcttgtccat agactttata accattgaaa
     7261 ggtgctggat tgtggcttgc agtaaccata ataccagcat aggcatttaa atggcgaaca
     7321 gcaaaggaga gttctggtgt tggacgaaga gcttcaaata cgtaagattt aattccatgc
     7381 tgtgccaaga cctgtgcaga ctcaaaagca aattctggag agaagtggcg cgaatcataa
     7441 gcgatggcta caccacgttt tttagcttcc tctcccttag tttctattaa ttttgctaat
     7501 ccttcggttg cttgacggac aacataaata ttaatacgat ttgtaccagc accaatataa
     7561 ccacgcatac cagcagtacc aaattctaag tttgtgtaaa aagcatcttc ttttgttttt
     7621 tcatccattg atagtaattc ttgacgaaga tagtcaggaa gctgctcaaa atctaaccat
     7681 ttttgaaaat tttctgtgta agtcattgaa atactccttc aatatttata aacgctttca
     7741 ttatatcatt t
//
LOCUS       DAUCXI010000064         7747 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.064, whole genome shotgun sequence.
ACCESSION   DAUCXI010000064 DAUCXI010000000
VERSION     DAUCXI010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7747
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.064"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            287..1330
                     /gene="pheS"
                     /locus_tag="VGY43_001634"
     CDS             287..1330
                     /gene="pheS"
                     /locus_tag="VGY43_001634"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEQ4302797.1"
                     /translation="MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGEERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            1540..3945
                     /locus_tag="VGY43_001635"
     CDS             1540..3945
                     /locus_tag="VGY43_001635"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEQ4302798.1"
                     /translation="MLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPADGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIEVAIASDK
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDK
                     FEDHKIVARAARQGESLVTLDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDGNS
                     QTVVLEAAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLPTEPVEVSTSLDYVNVRLGTELTFADIRRIFDQLGFGLTGDETSFT
                     VAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKEDLPNEVNHFAFAICGLVAQKDFQTQAQVVDFYHA
                     KGILDTLFANLNLKVQYVPTKDLASMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALSSDQTFVEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTKIKLFDVYEGVTIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQVGA
                     EVR"
     gene            4056..4433
                     /locus_tag="VGY43_001636"
     CDS             4056..4433
                     /locus_tag="VGY43_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HEQ4302799.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTLAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVTVTITLEGLSHV"
     gene            4426..4812
                     /locus_tag="VGY43_001637"
     CDS             4426..4812
                     /locus_tag="VGY43_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HEQ4302800.1"
                     /translation="MSDASLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFYCLIEEAQAIPPTVKSLRTAYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            4885..5961
                     /locus_tag="VGY43_001638"
     CDS             4885..5961
                     /locus_tag="VGY43_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEQ4302801.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAIDLWKADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNIVAWSVKNPKDA
                     DKVKVSLFGIDSNSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNARFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GISNKTITTAVLMQTFFLSFLGSGLGLLGTWLTSLLLPTVVPFQSNWFLYLAIFVSMI
                     CFALLGTLFSVFNIIRIDPLKAIG"
     gene            5971..6639
                     /locus_tag="VGY43_001639"
     CDS             5971..6639
                     /locus_tag="VGY43_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302802.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSHLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGIARLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLEYCDKVYRMQDGEL
                     RQER"
     gene            complement(6743..7660)
                     /locus_tag="VGY43_001640"
     CDS             complement(6743..7660)
                     /locus_tag="VGY43_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HEQ4302803.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSGVLGGKPSSTNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKTFREKGLTYHKPTLVLYTGATQTACGRGQASSGPFYCPGDQKVYLDISF
                     YNELSTKYGAKGDFAMAYVIAHEVGHHIQNELGIMDNYASARQGKSKAKANQLNVKLE
                     LQADYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEETYGRAVPDSFTHGTS
                     KQRQRWFDRGYQYGDFEHGDTFSIPYSKL"
BASE COUNT         2324 a         1412 c         1712 g         2299 t
ORIGIN      
        1 ggcgtggaaa agtcactgat ttaagattgt cactaagcac tttttttgat agaatagaac
       61 taattgaata agtgtctatg agactagtac taatagagaa attaacaggg agtgagggcc
      121 gtgactggaa gccttcttaa gggaactatt aggaattcac tcagctaaag acaattaatt
      181 aaggtctgat aacatcagat aaaaacggat ggtaccgcgt gtcaacgctc cgcttatgaa
      241 gtggagtagt ggcacgcttt tttcatcgct aaaagaaggg aaaactatgg atttacaagc
      301 acaattagag gaattaaaaa caaaaacatt ggagactctc caatctttga cggggaatca
      361 taccaaagaa ctgcaagatt tgcgcgtggc tgttcttggg aaaaagggat ctttgacaga
      421 attactaaag gggctaaaag acttgtctaa tgacttgcgt cctgtggttg gtaaacaggt
      481 gaacgaagtt cgtgacttat tgacaaaagc ctttgaagaa caggctaaaa ttgtagaagc
      541 tgctaaaatt caagcccagc ttgatgctga aagcattgat gtgactttac cgggtcgtca
      601 aatgactctg ggccaccgtc atgtgttaac acaaaccagt gaagaaatcg aagatatttt
      661 cttaggaatg ggttttcaga ttgttgatgg ctttgaggta gaaaaagatt attacaactt
      721 tgagcgcatg aatttgccaa aggatcaccc tgcccgtgac atgcaagata cgttttatat
      781 cacagaagaa atcttgttac gaactcacac cagtcctgtg caggcccgta ctcttgatca
      841 acatgatttt tcaaaagggc ctttaaaaat ggtttctcca ggtcgtgttt tccgtcgaga
      901 caccgatgat gctacccact cacatcaatt ccatcaaatt gaaggtttgg tcgtgggcaa
      961 aaatatttcc atgggagacc tcaaagggac tcttgaaatg atcatcaaga agatgttcgg
     1021 tgaagaacgt agcattcgtt tgcgcccgtc atatttcccg ttcacagaac catctgttga
     1081 agtggatgtt tcttgcttta aatgtggtgg gaaaggctgt aatgtctgca agaaaacagg
     1141 atggattgaa attcttggtg ctggtatggt tcacccaagt gtcttggaaa tgtcaggtgt
     1201 tgatgcaaaa gagtattcag gctttgcctt tggtttaggt caagagcgga ttgccatgtt
     1261 gcgttatggc attaatgaca ttcgtggttt ctatcaaggc gaccaacgtt tctctgaaca
     1321 atttaactaa aatgagtcgt ttgaagactt ctgtcagcta ttttatctaa gattgagtga
     1381 aagttgatag gtaatgataa taggttaatt gtctaagggg aaagtccctc tcgcttcaac
     1441 gtcataaggg ttttgacttg gaacttaaaa tacgaaagga aatgactcaa atcacggctt
     1501 gagagctttc tctagccgag tgatttgggc actaaaatta tgttagtatc ttataaatgg
     1561 ttaaaagaat tagtagatat cgatgtgaca ccggcagcac ttgctgagaa aatgtcgaca
     1621 acgggtatcg aggtagaagg aattgaagtc cctgcagatg gtttatcaaa actggttgtg
     1681 gggcatgtgc tttcttgcga agatgtgcca gagacacatt tgcatttgtg tcaggtagat
     1741 acaggtgatg aaacgccacg tcaaattgtg tgtggcgcac caaatgtgaa agcagggatt
     1801 aaggttatcg tggctgtgcc aggtgctcgt attgcggata actataaaat caaaaaaggc
     1861 aaaatccgcg gcatggaatc tcttggcatg atttgttcct tgcaagaact tggtttgtca
     1921 gatagtatta ttccaaaaga attttcagat ggtattcaaa tcttgccaga ggaggctgtg
     1981 ccaggtgatg ctatttttaa atacctggac ttggacgatc atatcattga attgtccatt
     2041 acacctaacc gtgctgatgc gctttctatg cgaggtgtgg cacatgaagt cgcagctatt
     2101 tatggcaagt cagtatcatt cccccaaaaa aatctacaag aatctgataa ggcaacttca
     2161 gaagccattg aagtggccat tgcctctgat aaagttctaa cttacgctag ccgtgtcgtt
     2221 gaaaatgtca aagttaagcc aagtccacaa tggttgcaaa accttttaat gaatgctggt
     2281 attcgtccta ttaataatgt ggttgatgtg accaactatg tgctcttgta ttttggtcaa
     2341 cctatgcatg cttttgatta tgataaattt gaagaccata agattgtggc gcgtgcggct
     2401 cgtcaagggg aaagtttagt cacacttgat ggtgaaaaac gggatttgac cactgaggat
     2461 cttgttatta ccgtggctga caaaccagtt gctttagcag gtgttatggg tggtcaagcc
     2521 actgaaattg atggcaactc tcagacggtt gttcttgaag ctgctgtttt tgatggcaaa
     2581 tcgattcgta aaaccagtgg tcgtttaaac cttcgttcgg aatcctcttc acgttttgaa
     2641 aaaggggtta actatgcaac tgttttagaa gcgcttgact ttgcagcggc tatgttacaa
     2701 gaattagcag aaggtcaagt cttatcaggt catgttcaag ctggacaatt gccaacagaa
     2761 cctgttgaag tctcaactag ccttgactat gtgaatgttc gtttaggaac agaattaact
     2821 tttgctgata ttcgaaggat ttttgaccaa cttggatttg gtctaacagg agatgaaaca
     2881 agcttcacgg tagctgttcc tcggcgtcgt tgggatgtta gcatcccagc tgacttggtg
     2941 gaagaaattg cgcgtatcta tggttatgat aagttgccga caaccttacc agaggcaggg
     3001 ggaacggctg cagaattaac gccaacacag gctcttcgtc gtaaagtccg tggcttagcg
     3061 gaaggactgg gcttgactga aatcatttcg tatgccttga caacaccaga gaaagctgtt
     3121 gagtttgcag tggcaccaag tcacctaaca gaactcatgt ggccaatgtc tgtggaacgt
     3181 tcagcgcttc gtcaaaatat ggtttcaggg atgttagata cggtagctta taatgtggct
     3241 cgtaaacaaa gtaacttggc tctttatgaa attggaaaaa tctttgaaca agaagctaat
     3301 ccaaaagaag accttcctaa tgaagtgaac cattttgctt ttgctatttg tggcttagtg
     3361 gcacaaaaag atttccaaac ccaagcacag gtagtggatt tttaccatgc taaaggtatc
     3421 ttggatactt tatttgcaaa ccttaacctc aaggttcaat atgtgccaac caaagaccta
     3481 gcaagcatgc acccaggacg gacagcgctt atcctattag atgagcaagt gattggattt
     3541 gttggtcaag ttcatccagg aacagcaaag gcttatagta ttccagaaac ctatgtggca
     3601 gaattggata tggcggcttt agaagcagcg ttgtcaagtg atcaaacttt tgtggagatt
     3661 accaaattcc ctgctatgac acgtgatgtt gccttgttac ttgaccgtga agtgagtcat
     3721 caggccattg taacagctat tgaatcagca ggtgtaaaac gcttgactaa gattaagctc
     3781 tttgacgtgt atgaaggagt aactattcag gctggcaaaa aatcaatggc ttatagcctt
     3841 actttccaaa atccaaatga caatttaacg gatgaagaag ttgctaaata catggagaaa
     3901 atcaccaaag cattgacaga acaagtcggt gctgaagtac gctaagaaaa aaaactgggc
     3961 ctctaaggct ccgttttttt ctgttataat agaggaaaaa agaactccag ttcaaatgat
     4021 tggagaaaaa catcagaagg tggaggaaaa tcagaatgta tcaaacaaaa ataacaggca
     4081 accgccttta ccacacggtt tcgaaaggct acggagatag tgtaacctta tttggaaaaa
     4141 ctgatcaagg ggaaacccct atgagtttac tggttattgc cttgtcttct tgtgtgacta
     4201 tgtgtgtgca gggtttttac catcgtcaat ttcagcaaga cacacttgct gtttctgttg
     4261 aggctagtta tgaggaagaa gtttttgaac tacttgttag gattgatgat gttttagatg
     4321 acaaaaagaa agctgattta ttggcttaca ttggaactta ttgtcgtgtg aaacaactcc
     4381 tcaaacctga agttacggtg accattacgt tggaaggact gtctcatgtc tgatgctagt
     4441 ttgaaaactt accaaaaaca atgggcttat caaaagtatt gggtcatggc acactcacag
     4501 cagcattaca atgctttaag agaattgttt aaaggaaatc agtggtcaga agaaaaggtg
     4561 ttgacttttt attgtttgat tgaagaagcg caagccattc ctcccacagt aaaaagctta
     4621 cgaacggcat atcagcatgt ttgggggtat tttaaaaagg tagcgagtca ggaagaaaaa
     4681 gaccatttca aagatttgga tgctcagttg gaaactaaat ctgaggagat gctatgcttt
     4741 ttacaagaga tgactgctca ttatcagccc tcttatctgc tatcttgccg tttgattacc
     4801 aaaggtcctt aaatgctaaa cagaaaagta gggatttctg ggaagttatg ctaagctagt
     4861 gatataaata agggggaatg agagatgttt ttagcgctta atgaaatgaa acaatccaaa
     4921 ttgcggtatg gtttgattgc tggtttgcta tgtttggttg cctatttgat gttctttttg
     4981 tcaggattgg cctttggttt gatgcaggag aaccgctcgg cgattgatct ttggaaagct
     5041 gacagtgttt tactagccaa ggatgctgac gctaccttga ccttatcaca ggtgtccaga
     5101 gctcaagaaa atcaaataac agcagacaag gtagctcctc ttgctcaact caatatcgtg
     5161 gcgtggtcag ttaaaaatcc taaggatgcc gacaaagtta aggttagcct tttcgggatt
     5221 gattctaata gctttattcg tcctaacatt gtaaaaggtc gattatttaa gactaacaaa
     5281 gaggttgttt tggatcaaag ccttgcaaaa gaggaagctt ttgcgattgg caaggacttt
     5341 tacacatcga gttctagtca agcattaact atcgttggtt atactcaaaa tgctagattt
     5401 agtgttgcac cagtggttta tatgaatttg gaagcttttg aaacattaaa atatggagaa
     5461 ccactaccaa aagataagca agttgttaat gcttttatca ctaaaggaag tttaacagat
     5521 tatcctaaaa aagacttcca aaaattagat attaaaacct ttattactaa attacctggt
     5581 tatagcgctc aacttttaac ttttggcttt atgattagtt ttcttgtcat tatttcagct
     5641 attattattg gtatttttat gtatattttg actattcaaa aggcacctat ttttgggatt
     5701 atgaaagcgc aaggaatttc taacaaaacg attacgaccg ctgtgcttat gcagacattc
     5761 tttttgagtt ttttaggtag tggtttaggg ttgctaggta cttggctgac atcattatta
     5821 ttaccaacag tagtaccttt tcaaagcaat tggtttttgt atttggctat attcgttagt
     5881 atgatctgtt ttgctctatt aggcacctta ttttctgttt ttaacattat acgaattgat
     5941 cctttgaaag caattggata ggagatagtg atgtcggttt taacatttaa acaagtgacc
     6001 aaaacatttc aagatggtca tcacgaaatc aacgcattaa aggcaactga cttttccatt
     6061 gaagctggag aatttgtggc tattattgga ccatcaggtt ctggaaaatc aacctttttg
     6121 accattgctg gtggcttaca gaccccaagc tctggtcagt taatcattga tggcactgat
     6181 tatacgcatt tatcagaaaa agagcgctca cacttgcgct tcaaatccgt tggttttatc
     6241 ttacaagctt ccaatctgat acctttttta acggtccagc agcagttgga attggtcgat
     6301 catttgacag gaagcaaaga aaaagccaaa gccaatcagt tatttgatga tttaggcatt
     6361 gcaaggctaa aacatcagtt acctcaagaa ttatccggcg gagaaaggca aagagcggct
     6421 attgcccgtg ctctttacca tgatccagca ctaatattgg cagatgaacc tactgcaagt
     6481 ttggatactg aaaaagccta tgaagtggtc aaactgttgg ctaaggaaag taaagaaaaa
     6541 aacaaggcca ttattatggt cactcatgat gatcggatgc tagaatattg tgacaaagtc
     6601 tatcggatgc aagatggaga gttacgtcaa gagagatagt agactggtaa gagtttatga
     6661 tattagaaga aaaaaccaaa caagcacagc acttgtctgg tttttttcta agtgtgacta
     6721 ttatcaatac gtcaccattt ccctaaagct tactatacgg gatgctaaag gtatcaccat
     6781 gctcaaagtc gccatattgg taacctcggt caaaccaacg ttggcgttgc ttagaagttc
     6841 cgtgggtaaa actatcagga acggctctgc cataggtttc ttcttgcaga gtatcatccc
     6901 caactgcgtg agctgctgcc attgcctcct caatgtctcc tttttccaaa aggccttgcc
     6961 cttgaacata attagcccag gcaccagcat agtaatcagc ttgtaattcc aacttgacgt
     7021 tgagctgatt ggctttagcc tttgattttc cttgtctagc gctagcgtaa ttatccataa
     7081 ttcccaattc attttggatg tggtggccaa cttcatgagc aatcacatag gccatagcaa
     7141 aatcaccttt tgcgccgtac ttggttgata gttcattata aaaagaaata tctaaataca
     7201 ctttttgatc gcctgggcaa tagaaaggac cagaagaggc ttgccccctg ccacaagcgg
     7261 tttgagttgc tccagtatat agaactaatg ttggtttatg ataagttaac cctttctcac
     7321 gaaatgtctt agtccaatag tcctcggtag aggcgaagac cttactgaca aaagaaacct
     7381 gttcttgact agccttgtca ccatttgtac gcgttacttg gcttgattga taggcattgt
     7441 tgttggtaga agaaggcttg cctcctaaaa caccagatag gccacctcct cccataacta
     7501 ggagaaggag aagaataacc agcttggttt tccaacctcc tcgtgaaaag agtaattgaa
     7561 gcaggagacc gccccctagg ccgccgcccc caaaagaacc agacgattga ccacgtctat
     7621 cttcaacctg ttgactttct ctcaaatcat ctgttttcat aagtttctcc catctatttc
     7681 ttgattttat tataaaataa ttctattaga attgctattt ttatgatgag attataacta
     7741 aaaatag
//
LOCUS       DAUCXI010000065         7527 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.065, whole genome shotgun sequence.
ACCESSION   DAUCXI010000065 DAUCXI010000000
VERSION     DAUCXI010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7527
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.065"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..183)
                     /gene="speG"
                     /locus_tag="VGY43_001641"
     CDS             complement(<1..183)
                     /gene="speG"
                     /locus_tag="VGY43_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeG"
                     /protein_id="HEQ4302804.1"
                     /translation="MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPC
                     DYENVEIAFVTTNSIHI"
     gene            complement(285..382)
                     /gene="ffs"
                     /locus_tag="VGY43_001642"
     ncRNA           complement(285..382)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VGY43_001642"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            582..1814
                     /locus_tag="VGY43_001643"
     CDS             582..1814
                     /locus_tag="VGY43_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEQ4302805.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNVYQDLQAIGNDIVANTPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQSQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDYLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILASLENQLLNRQEQLSLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            complement(2428..2943)
                     /locus_tag="VGY43_001644"
     CDS             complement(2428..2943)
                     /locus_tag="VGY43_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEQ4302806.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(2943..3722)
                     /locus_tag="VGY43_001645"
     CDS             complement(2943..3722)
                     /locus_tag="VGY43_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEQ4302807.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGHDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFA
                     KLSIPDVSEGRAYDVTGVEQIGPFDITFLKTVHPVVCYAFRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQARVKKLVLTHMPPVP
                     PEGINSKNHLEVLRQETQAYAGNIPVDLALPHKSWNLGSLS"
     gene            complement(3862..4401)
                     /locus_tag="VGY43_001646"
     CDS             complement(3862..4401)
                     /locus_tag="VGY43_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEQ4302808.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLAAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTKQ"
     gene            complement(4405..4716)
                     /locus_tag="VGY43_001647"
     CDS             complement(4405..4716)
                     /locus_tag="VGY43_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302809.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCAFCQTYYACYHCHDQ
                     LTDHAFVPTGHQEISPVICGHCRKLLSLAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            complement(4933..6075)
                     /gene="tgt"
                     /locus_tag="VGY43_001648"
     CDS             complement(4933..6075)
                     /gene="tgt"
                     /locus_tag="VGY43_001648"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEQ4302810.1"
                     /translation="MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            6294..7157
                     /locus_tag="VGY43_001649"
     CDS             6294..7157
                     /locus_tag="VGY43_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEQ4302811.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGVILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     ANLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGSSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDKVKEGTYLGAIAVIKTSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKK
                     PTPMMYDDQKD"
     gene            7354..>7527
                     /locus_tag="VGY43_001650"
     CDS             7354..>7527
                     /locus_tag="VGY43_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ4302812.1"
                     /translation="MIRLIDRYGVTIVQKCKNNYYSPELKQEIINKVLIDGQSQKQTS
                     LDYALPTSSMLSRW"
BASE COUNT         2354 a         1551 c         1349 g         2273 t
ORIGIN      
        1 aatatgtatg ctatttgtag taacaaatgc aatttctaca ttttcataat cgcatggggt
       61 aatattatag gcaaacctta aacttctttt taaatctttt aaattttcat ctgcataagc
      121 taattgactt ccatagctaa aaacacatga taatatgata attgtcaaaa tgtttgtttt
      181 catttaaaac tttttatgtc ctgttttata cctcttaacc taaataaaaa tatcaatcgg
      241 tttcaacaac tgatgacact atagaaggag gagattactt tagtaaagtc aacaaaaaag
      301 agcacacacc cgaaaatcgc ttagggctgc tggattcctc ccctgaccca cttcacgcac
      361 aagtgttgct ccgcctatta ttatatcata ttacggacag tttgcaagtt ttccaactaa
      421 gtaaaatcac tttcaagtga gaatagcttc attttgggac aagatggact gaatacctag
      481 aaaaatcatg accctttcca aacacgattt tgctttttga aaatctttcc ctctccccat
      541 tccagctatt ctctatgtta taataagatt attagattag aatgggagtt atgatgaaac
      601 aaaagattaa aatcttaaca gtaattggcc ttatgacagt tggtatgtct gcgtgtcaca
      661 acactagcaa accttctaat accgattctg ttttttcttt aaccggaaaa aagcgccaac
      721 aaatcgtcaa acaagtaaga caacggtatt atttccaaca attatccaaa accgaacaag
      781 aaaattacct cactttatac gatagtctag cacaatttcg tgaaatcatc agtttgacgc
      841 cggcttctaa aaaaagctta attaaaacga ttgacgcctt tgtgatggat aatcccgaat
      901 tttactggat tacatctgcc gattatcgat ttgagttttc tgatcaaacg gtctttgtca
      961 cctttcctat cccagaagat gccaagaacg tttatcaaga cttgcaagca atcggtaatg
     1021 atatcgtcgc aaacacgcca tcaaaggatc gctatgagca ggtcaaatat ttttatgagg
     1081 tcatcattcg agacacagac tacaataaaa aagcctttga agcctatcaa tcaggcagtc
     1141 aatcccaggt cgcttctaat caagacatta aaagtgtttt tattgatcat ttatctgttt
     1201 gtaatggcta tgcccaagcc tttcagtttc tttgtcaaaa agctggcatt ccagtcgcct
     1261 atatccgtgg aactggtaca tctcagcaac ctcagcaatc ttttgcacat gcatggaatg
     1321 ctgttcaaat taataacact tattatggcg ttgatgtcac ttggggtgac cctgtttttg
     1381 ataaccatct ctcacatcaa aagcaaggaa ctatcaatta cagttttcta tgcctaccag
     1441 attatctaat ggccttatca catcagccaa gcaaagacat tgcttttaat actaaagaac
     1501 gttttgaaaa tgtttggact ataccttctt gtacagatga ttctttgctt tattctaaac
     1561 gtcatcaaag ctatatctca acgtttgaca gtgacgccat ccttgcaagc cttgaaaatc
     1621 agttgttaaa tagacaagag caactgtctc tacaatttgc tcatcaagat gattatcaac
     1681 aaatggtaac tgatttaacg acgaatcaaa caggttatca taaccttttc aatcagtatt
     1741 ggaataatta tacgggcttt acctatggac tcttaccaga gactcttagt atttcatttg
     1801 ctagtaggaa ctaggtttag acacatgaaa cacaaagtta agatgattat ctttgtcaaa
     1861 cattacaaga aattgatata ctaacacaat tgaaggcgat tattattcta accgtcttca
     1921 atagatataa ccttttcaga ttgagcacat ctaatgcttg taacattagc aacagtgatg
     1981 agctcttttt taatgcttta gcaaaatata tcagctaaga caaaagatta aataactcaa
     2041 gtcatgccta taagtcactt gtttttaatc cctgtgtcag tgtcaatcta cgccacagat
     2101 aactgacagc tctgagccct agaagtctga acttgataag tttactaaaa acaaaaataa
     2161 ggtgagccat tactatctgt ttttagatag taaatctttt taagaatgac taactcatct
     2221 agtcatcacg tgttttattt ttcgattgtt ttcatctcga ttgggtctga aaaagagcgc
     2281 ttctagtact tggaaacgcc cttttgtata ttctatcttc gtatgttgaa tctaacaacc
     2341 attggaaaaa tggtctgacg tttcactcag tattttgaca ggctaccctt caccaaaaat
     2401 gcatgtgata acaaactcct taaaactcta gtcaaaggga tctgactgtt ccttgatcaa
     2461 atgcttagct atttttttgc gctctcgccc ttggcggaaa aaggtttgca tgatgttagc
     2521 acagtctgct gctagcaggc ctcgttcaac ttgcacgcgg tggtttaagc gctcatctgt
     2581 caaaatctgg taaaggctgt ctgctccacc aaatttttga ttgctggctc cataaataac
     2641 atgcggaatc cttgctagcc caatggcacc actacacatc acacaaggct cgatggtcac
     2701 aaagagtgtg gtgtctaata aacgccagtt gccttcatga gcgttagcct cgttaatagc
     2761 catcatttca gcgtgcataa tggcttggtt actctcttca cgcgcattgt gcccacgacc
     2821 aataatctca ccatccttga caatgacaca gccaatgggg atttcagctt tctgtaagga
     2881 tttttcggct tcttttaaag cctcttgcat gaaataagtt tgctcttcta aactatatgg
     2941 catcaagaaa gactccccaa gttccaagat ttgtgtggta aggcaaggtc aacaggaata
     3001 ttacctgcat aggcctgtgt ttcttgcctc aacacttcta aatggttttt ggaattaata
     3061 ccttctggag gaaccggtgg catgtgggtc aagacaagct tcttaacacg tgcctggcta
     3121 gccattagtc ctgcttcctt actggtcaaa tgggccatat gattttcatt gccttcgtat
     3181 aagtaaacat ccgctaagaa aaggtctgct tcttttgcga agtctgccaa tccttcaaaa
     3241 taaccactgt ctccagtaaa gacaagtacc tgaccagtcg ctctttctac aattcgaaag
     3301 gcataacaca caactggatg aactgtttta agaaaggtaa tgtcaaaagg accaatctgt
     3361 tcaactccag taacatcata ggctctacct tctgaaacat caggaatgct taacttagca
     3421 aattcgtgtc ggtcctcatc atgcccataa atgggcaata ctttaggctg ccacaggtgt
     3481 ttaggataaa gttgaaaata atggcgcaac acgcctaaat cggccacgtg gtctggatgg
     3541 taatggctaa taatcactgc atccaaatcg agaggactga tttctttttc cagctcattg
     3601 agcgctcgac taccagcatc catcaataac tgaaagccgt catgtcctgt gaccaaataa
     3661 gaggttgtgc ctgcatcttg atagggatag gctccccaag accctaaggt ggttaatttc
     3721 atctcaaacc cttctttctt gctttaactc ttattataac aaaaattagt gtcaaagagg
     3781 attgagaccc accaaaaaca ggtcctagca gataaatctg ccaagacctg ttcaacacaa
     3841 cttaactatt tgatgattag attactgttt tgtattcaaa aaactatctt tgtatttaac
     3901 agcgataatg gtcgcaatga ttgctttgat ggtatctcct ggaataaaga ccaagtttga
     3961 caaaagcgat gtcacaagag acatgccagt gtaggctgcc aaccagatag cacccagaac
     4021 atcaaccagt acaactcctg agattaaaag agctaggaat gctaatggcg tgctttttga
     4081 gaaccagttg cggtaaagta atgaaaagac aataggcaca agaaggtagg caataacata
     4141 gccagcagat ggccccatca atactggaat ggttgttctt gagcctgaga aaacaggtaa
     4201 gaaaaggcca atcactaaaa ataagaaaac agataaggtt ccctttttac cacccagcat
     4261 caatccagcc aacatgacac ctaagttttg taaaacaata gggactggga taaagcctag
     4321 cgggatagca ggaataaagc ctaaaataat aatcaaagtg gtcatcatag ccaccttaac
     4381 aagttctttg gttgtaaaca tcagttacga ctcctttaaa aaatagatat ccttgtgcct
     4441 atgacaggct ggattaaagg gactttgaca ataaggacag catccacaac catactcagc
     4501 taggctcaag agctttcgac aatgcccaca aataacagga gatatttctt gatgtcctgt
     4561 tggcacaaag gcatgatctg ttaactggtc atggcaatgg taacaagcat aataagtctg
     4621 acaaaaagca catttgagcc caacaatatc aagcggggta tgataatgta ggcaccgata
     4681 ctcttggtca aggtcaattc caaaacagtc cgtcatatct catcctcttg taatagttta
     4741 atcaaaagct tatagtttgt caactctatt tttacaaaag ggtaactgct ttctgaaaaa
     4801 gaacacgtaa aacaagaact tccctttaaa gagtgaccta tcagttgaaa gcaataggac
     4861 atccgtctat acaaaaaaac tgaaaccaaa gacgatagat cgccctcagt tccaggatca
     4921 tagcattttt aattagaaat tacggtttga tttattataa ccataccgtt caagaaaatc
     4981 ttggcggaat tcaagtaagt tatcgtccat aatagcctga cgtacttttt tcatcaagtt
     5041 aaccaagaaa taaaggttgt ggtagcttgt caaacgaata ccaaaagttt catccgcttt
     5101 tagcaagtga cgaatgtagg cacggctata gttttgacaa gtgtagcagt cacagtcatg
     5161 atcaagtggg gtaaaatctt cagcgaattt ggcattttta accacaagac gcccctcact
     5221 agtcatgcag gtcccattac gagcgatacg cgttggcaag acacaatcaa acatatcgac
     5281 accacgaatc acaccatcaa tcaagctatc tggtgctccc actcccatca ggtaacgagg
     5341 tttattttct ggtaagaggg gagtcgtaaa gtcaaggacg gcattcattt cttcatggct
     5401 ctccccaaca gctaaaccac caatagaata acctgggaaa tccatagcca ccaaatctgc
     5461 cgcagactga cgacgaaggt cctcaaatcc agctccttgc acaattccaa ataatccttg
     5521 gtcatgagga cgacgatggg cttttaggcc acgttctgcc caacggctag tacgttcaat
     5581 ggattttttc acgtaatcat aaggttggta aaattgcggg cactcgtcaa aactcatcat
     5641 gatgtctgag ccaaggttat tctgaatgga aatggctttt tcgggtgata gaaacatttt
     5701 tgagccattc aagtgatttt tgaaagtcac tccttcttca gtgatgtttc gtgaatcggc
     5761 taaagagtaa acttgaaaac cacccgaatc ggttaagatt ggctgatccc agttcataaa
     5821 cttgtgcaga ccaccagagc gagcaatcaa ctcatctcct ggacgcaacc agaggtgata
     5881 agtgtttgat aaaataatcc ctgacccaat agcttttaac tcttctggag actgtgtttt
     5941 aacagtagcc tgagttccca ctggcataaa cattggtgtc ggaaaggtcc cgtgaggtgt
     6001 gataatttcg cccaagcgtg caccggtgtg cttttctgtt ttgataaggc gatacttaat
     6061 cggataatct gtcatgtgct ttcttccttg ctatcaagat aaacagtctt gagctttttt
     6121 gatctgcctg agtttccatc ataatgaagg gcttcaagat gacatgttgt tctagcgcct
     6181 atcattttat caaaaaatcc ataatttgtc atgctttccc aaaaaagtat agtcaaaata
     6241 atggttagct gtctcatttt gttttatggt ataatgaaat aaaggagtct gttatgtcaa
     6301 ttaaagcaat caaaggccag gctagagaca cgttaaaaaa tctctctggc aagtatttac
     6361 tatttttaat tccaaccctt ctctttatgt ttcatttcgg tattgagatt catcaaggtt
     6421 acgtcctatc tagtggtatt gaagtctcgc tagcggctag ttatttccca ttactactag
     6481 gagttatcct tagccttttc attttatcag catcctttac aatgattgat gttgttaggc
     6541 attttcgtca gaaagtttct tttgccgaat caacaacagc cttctcaaaa gaattctttg
     6601 cgaacctgct ggttttagcg atcactaagt ggctattctt tctcatctgg tcactaattt
     6661 ggttttttgg cctctttatt ttcctttccg gactttcagc gtttttggtc aatgctaaat
     6721 caggtagctc aacagtcatt tcactgatct ttttactatt tggagcagtt ttgtccttaa
     6781 ttggttttgg tatttatatc aaccgttatt acgcttatag tctatcagaa taccttctct
     6841 acgataaggt taaagagggg acttatctag gagctatagc cgtcattaaa acaagtgtag
     6901 ctatgatgaa aggttataaa tggaagcttt ttttcctaca acttagcttc accggttggt
     6961 ttctactgaa tattgttact tttgggttac ttaatatcta tcttttacca tattttacaa
     7021 cagccaatgt cattttttat gatcaactca agaaacgttt caaagacaaa gatgacccaa
     7081 ttgaaggaga acatttaagc cttcatcagc ttaataaaaa gcctactcct atgatgtatg
     7141 acgatcaaaa agactaaata aatcctccgt ccataaaaat agcccttgaa ctgcacccca
     7201 aaagttagac acaaagtcta acgattgggg tgctattttt ttatgaaatt taatcaagaa
     7261 acgaaagtta agatttatga gttacggcaa atgggagagt ccattaaatc catatcaaaa
     7321 aagtttgata tggcagaatc cgatctcaaa tatatgattc gcttgattga taggtatggg
     7381 gtaaccattg ttcaaaaatg taagaataat tattattctc cagaactgaa gcaagagata
     7441 ataaataaag tcctgattga cggccaatct cagaaacaaa catccttaga ttatgcttta
     7501 ccaacttcta gtatgctctc aaggtgg
//
LOCUS       DAUCXI010000066         7166 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.066, whole genome shotgun sequence.
ACCESSION   DAUCXI010000066 DAUCXI010000000
VERSION     DAUCXI010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7166
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.066"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            53..1318
                     /gene="purD"
                     /locus_tag="VGY43_001651"
     CDS             53..1318
                     /gene="purD"
                     /locus_tag="VGY43_001651"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEQ4302813.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTGAYGTFSDFEKAKAYIEEQGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFVNGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVRPVLEGMIAEGRPYLGVLYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQNDGVTLGVVVA
                     SEGYPLDYEKGVPLPEKTDGDIITYYAGAKFAENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDTTGLFYRNDIGSKAIRE"
     gene            1596..2087
                     /gene="purE"
                     /locus_tag="VGY43_001652"
     CDS             1596..2087
                     /gene="purE"
                     /locus_tag="VGY43_001652"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEQ4302814.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            2074..3147
                     /gene="purK"
                     /locus_tag="VGY43_001653"
     CDS             2074..3147
                     /gene="purK"
                     /locus_tag="VGY43_001653"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEQ4302815.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPTNDCPASRV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQLPQGTDLLRISQNR
                     IVEKDFLANKAGVTVAPYKVMTSSLDLGGLDLTKTYVLKTATGGYDGHGQKIIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGEDVTVFPVQENIHCNNILSKTIVPA
                     RISDQLADKAKKMAVQIAKKLQLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPTIHLHAPAVMLNVLGQHVQQAIDYVTENPSAHLHMYGKLE
                     AKHNRKMGHVTLFAEDADEVEEF"
     gene            3168..4497
                     /locus_tag="VGY43_001654"
                     /pseudo
     CDS             3168..4497
                     /locus_tag="VGY43_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184068.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4866..6158
                     /gene="purB"
                     /locus_tag="VGY43_001655"
     CDS             4866..6158
                     /gene="purB"
                     /locus_tag="VGY43_001655"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEQ4302816.1"
                     /translation="MISRYSRPEMAAIWTEENKYRAWLEVEILADEAWAELGEIPKED
                     VVKIREKADFDIDRILEIEQDTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEQYVCYKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDIKVTSCLTQEEIDELFNPIYYTKRVDDIFKRLGI"
     gene            6292..>7166
                     /locus_tag="VGY43_001656"
     CDS             6292..>7166
                     /locus_tag="VGY43_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ4302817.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKVAVDIIQAKFEVYQTGDINFGYSILKEFLPQLKRKSIYNLNE
                     LLLIDLYLIILVVSHFSDDIFDVQFYEEITESMLKQHNNLPLEDLFLLNNILLSCADT
                     YIRLKMFGRLKETLQLSHFIMSTIQDFQKMPMYCMYEWKLSIFYLKDINRARNYFEQS
                     ILFTQMTGDTYLVQK"
BASE COUNT         2176 a         1303 c         1631 g         2056 t
ORIGIN      
        1 ggcgaacgtt tatgatataa tatctaatta taatacgaaa gaggtggatg ttttgaaatt
       61 acttgttgtt ggttcaggtg gtcgtgaaca tgcgattgct aagaagttgt tagcgtctaa
      121 gggtgtggat caggtttttg tggcacctgg taatgatggt atgaccttgg atggtctgga
      181 cttggtgaat atagtagttt ccgaacattc caggttgatt gcctttgcta aggagaatga
      241 gatttcttgg gcctttattg gtcctgatga tgcgctagca gctggtatcg ttgatgattt
      301 caacagtgct ggactcagag cttttggtcc aaccaaggca gcagcggagc tagagtggtc
      361 aaaagacttt gccaaggaaa tcatggtcaa atacaatgtc ccaacaggag cctatggcac
      421 attttcagac tttgaaaaag ccaaagccta catcgaagag cagggcgcac ctatcgtggt
      481 caaggctgat ggcttggcgc taggtaaggg tgtggtcgtg gctgaaaccg ttgagcaggc
      541 ggtagaggcg gcgcaagaga tgcttctgga caataagttt ggcgattcag gagcgcgtgt
      601 ggttatcgag gaattcttgg atggcgagga gttttccctc tttgcctttg ttaatggtga
      661 taagttctac atcatgccga cagctcagga tcacaagcgt gcctttgacg gagacaaggg
      721 gccaaacact ggtggtatgg gtgcctatgc gccagttcct catctacctc agagcgtggt
      781 ggatacagcg gttgagacga tcgttaggcc tgtccttgag ggtatgattg ccgaagggcg
      841 tccttatcta ggcgtcctct atgcggggct tatcctgacg gctgatggtc ctaaggttat
      901 cgagttcaac tcacgtttcg gtgaccctga aactcagatt atcctccctc gcctgacttc
      961 cgatttcgct cagaatattg acgatatcat gatgggcatt gagccttaca tcacttggca
     1021 gaatgacggt gtgactttgg gtgttgtcgt tgcctcagaa ggctatccgc tcgattacga
     1081 gaaaggtgtg ccactgcctg aaaagaccga cggcgatatc atcacctact atgccggagc
     1141 taagtttgcg gaaaatagcg agctacttct ctcaaacgga ggacgtgtct atatgctcgt
     1201 caccacagaa gacagcgtca aagcagggca ggacaaaatc tatacccaac tggcccaaca
     1261 agacacaaca ggtctcttct accgaaatga catcggaagc aaagctataa gagaataaga
     1321 ctaatcattc aaatattagc gtcagcaatc agcgaccgaa ggtcgctcca aaaagaaaga
     1381 agaaaggaac tgaacacggg actaatttcc taggaaaaaa ataaaactac ctggacgcaa
     1441 gcgtcatcgt tagttttctg cgtcgtaggc gtctgatgct aaagcaccta gtcgccctga
     1501 cgtgggttcg tcttcgaaat caaagatttc ggacttaccg catatttttc tacggaaagt
     1561 ttcgacaagt cgaaacgccc ctttatatct taattatgaa aactccaatt atttctatta
     1621 tcatgggctc caaatctgac tgggcaacca tgcaaaaaac ggctgaagtt ctagacaact
     1681 ttggcattgc ttacgagaag aaagtcgtct ctgctcaccg cacgcccgac ctcatgttca
     1741 agcatgctga ggaagcacgt ggtcgtggca tcaaaatcat catcgcagga gcaggtgggg
     1801 cagctcactt gcctggtatg gtggcagcta aaacaacgct gcctgttatc ggtgtgcctg
     1861 tcaaatcacg tgccctttca ggtttggatt cactctattc cattgtgcag atgcctggcg
     1921 gtgtgcctgt ggcaaccatg gctatcggag aagcgggagc gactaacgct gccctgacag
     1981 ccctccgtat cctttctatc gaggaccaaa atctggctga tgcgctagct catttccatg
     2041 aggaacaagg aaaaatcgca gaggagtcaa gtggtgaact catttaagac cattgggatt
     2101 attggtggtg gtcagctagg gcagatgatg gccattgcgg ccatctatat gggccacaag
     2161 gtcatcacgc tggatcctac taacgactgc cctgcctccc gcgttagcga ggtaattgtg
     2221 gcgccttacg atgatgttga ggctttggga caattggctg cgcgttgcga tgtgttgact
     2281 tatgagtttg agaatgttga tgcggacggt ttggatgccg ttgtgtcagc ttgtcagcta
     2341 ccgcagggga ccgatctgct ccgcatttcc caaaaccgta tcgttgaaaa agactttctg
     2401 gcaaataagg ctggtgtgac agtcgctccc tataaggtga tgacgtctag ccttgaccta
     2461 ggggggcttg atttgaccaa gacctatgtc ctcaagacag cgacaggtgg ttatgacggt
     2521 catgggcaaa agattatccg ctcagcagaa gatttgccag aggcgcagca attagctaac
     2581 tcagctcagt gtgtcttgga agagtttgtc aatttcgacc ttgaaatctc agttatcgtg
     2641 tctggaaacg gagaggatgt gacggtcttt cccgttcagg aaaatatcca ctgcaataat
     2701 atcctgtcaa aaactatcgt gccagctcgc atctcagatc aactggctga taaggctaag
     2761 aaaatggcgg tgcagattgc caagaaactc cagctgtcag gaactctctg tgtggaaatg
     2821 tttgcgaccg cagatgatat cattgtcaat gaaattgccc cacgtcccca caactcaggg
     2881 cactactcaa tcgaggcttg cgacttttca cagtttgaca cccacatttt gggcgtgcta
     2941 ggagcgccgc tcccaaccat ccacctccat gctccagccg tcatgcttaa tgtcctcgga
     3001 caacacgtcc agcaggcaat tgactatgtg actgaaaacc ctagcgccca cctccacatg
     3061 tatggtaaac tagaagcgaa acataaccgc aaaatgggac atgtgacact atttgcagaa
     3121 gatgcggatg aggtggagga gttttagaac aggagtagat tggtaagatg gagttaaggg
     3181 aatttaaagc gtggttatta aaaaaccatt ttgaagaaga tgagttatac aaggaatcta
     3241 taaagtgtta tcaagtggaa gcatataagg ctgcctatat tttttcgtat ttagcaaatc
     3301 ataagttcat tgctaaatta gctattgact acagtggtgt cccatcaaat tttatgtcta
     3361 aatttcccga tgatgaagtt agaaagtcga gttggcaaaa acgtgtgaat tccttaaaaa
     3421 atgaagatga gtgggagcag acggttaacg aaaaattaat tcaagcatgg gaagatgata
     3481 atgtattcaa attacctttc aaaattaaag aaaaatattc tcatatgagg gtattgcgta
     3541 ataatgcagc ccatgcgaaa gaccgtcgaa tttctgaatc aacagtttta gaattatgga
     3601 atgaaattga gtatatatat ccttactttg taatcaacgg aacgattgat gcatggatgg
     3661 aagatttaga aaaactagtt agatattcaa atagtagcat agaatctcaa aaccaattac
     3721 agaataaatt tggagatttt tctactgaaa ataagacctt aattgttaaa aagattatac
     3781 aaaaatattt ggtagattct gaatgggatg aaacgtaccc agatatagtg atgaattttt
     3841 tattatatat ttaattatat taatcaaatt ggtaaagact taacggaaaa agaggaattg
     3901 tatctgtcta ttggaacagg tatttatcat ttccaagctg aagctattga tattttttct
     3961 caatttgaag agtctctgag tgattataca tttagatatt tttgtgaaga attttcggat
     4021 aatttttgga agtttattga ttctatggat tccgaagtta ataaagagaa cttgacagct
     4081 actagtttag aaattttgaa gaaaaattct gctattttag taaatgcaga atttaatgag
     4141 agccgatttt tatctgataa tagtcttttt ttcaaatctg tgttagataa aattaagcat
     4201 ttatattact atactatgca tcatacgggt caacgtcatc ataatacaaa tacttttgac
     4261 tattcaaaat ttaattcata tattccttat attaactata tattttatag gatatcgtca
     4321 aatcctggat taaaagaaga tgaaaaagta atagattttg ttaagaggtg taataattta
     4381 atttcaagtg actatagtgc agaatcttgg tatagtgagc gtcaaatgca ggatgtaatt
     4441 aaaaaaatta atgaaaaata cactatattg gaagatagtg gaagggagtc ggattaatca
     4501 aattaaattt ggtagagagt ttaggaaatc taacttactc attctaaatg ctaaggaaat
     4561 taagttaaaa aatagaaagg aacaagggta gtcgtattcg ctaaactgaa tacaggctac
     4621 ggacttcctt aactcacaga attttaagca atacaagaaa ggagtgaggg tgtttccgag
     4681 tatttgaact cgggctaact tatctcctca atacaaatca aataatagaa aggaaatggg
     4741 cactagtttc actaaactga acccgagcgg aaagctcgga atttagataa accgcctagg
     4801 acgcaagcgt ccattgttgg tttcctaaaa ttcagtcgct ttctggtcgc ccttggtatc
     4861 ttaaaatgat ttcacgttat tcacgccctg agatggcggc aatttggaca gaggaaaata
     4921 aataccgtgc ttggttggag gttgagattt tggctgacga ggcatgggct gagttgggtg
     4981 agattcctaa ggaggatgtg gttaagattc gtgagaaggc ggatttcgac attgaccgca
     5041 ttcttgagat tgagcaggac acacgtcacg atgtggtggc tttcactcgt gcggtttctg
     5101 aaacgcttgg tgaggagcgc aagtgggtgc actacggttt gacgtcaact gacgtggtgg
     5161 acactgccta cggttacctc tacaagcaag ctaacgacat tatccgtcgc gatcttgaga
     5221 atttcaccaa tatcgtggca gacaaggcgc gtgagcacaa aatgaccatc atgatgggtc
     5281 gtacccacgg tgttcacgcc gagccaacga ctttcggtct taagttggcg acttggtaca
     5341 gcgagatgaa acgtaatatt gagcgttttg aacatgctgc cgcaggtgtg gaagctggta
     5401 agatttcagg tgccgttggt aactttgcta atatccctcc atttgtggaa caatatgtct
     5461 gttacaaatt aggcattcgt ccacaagaga tttcaacaca agttcttcca cgtgacctcc
     5521 acgcagaata ttttgcagtg cttgcaagta ttgcaacttc tatcgaacgt atggcgacag
     5581 agattcgagg tctgcaaaag tcagaacaac gtgaagttga agaattcttt gccaaaggtc
     5641 agaaaggtag ctctgctatg cctcacaaac gcaacccaat cggttcagag aacatgacag
     5701 ggctagcgcg cgtgattcgt ggtcacatgg tgacagctta tgagaacgtg tcactttggc
     5761 atgagcgtga tatttcacac tcatcagctg agcgtatcat cacacctgac acaactatct
     5821 tgattgacta catgctcaac cgctttggca atatcgttaa gaacttgact gtcttcccgg
     5881 aaaatatgat gcgcaatatg gaatcaactt ttggtttgat ttatagtcaa cgtgttatgc
     5941 tcaaattgat tgaaaaagga atgacacgag aagaagctta tgacttagtt caacctaaga
     6001 cagcttattc ctgggacaat caagtggatt tcaaaccact tttagaagaa gacatcaaag
     6061 ttacctcttg tcttacacaa gaagaaattg atgaactatt taatccgatt tattacacaa
     6121 aacgtgttga tgatattttt aagcgtttag ggatttaata taaaaaaaag aaggtgattc
     6181 ccttcttttt ttgtttaaaa aaacgaatat tttctttaaa aatattaaaa aggttagttt
     6241 tttgattaga cgctgtgata taataaagaa aacagttgtt ggagagaaac catgttagaa
     6301 cattttggtg gaaaagtaaa agtgttaaga cttgaaaaga ggattagtcg cgaggacttg
     6361 tgtggggatg agtctgaact ttctgttcgt caattagcac ggatagaact aggtcaatcc
     6421 ataccaagtt taagtaaggt tatttttatt gcaaaagcct taaacgttag tgtcggttac
     6481 ttaactgatg gtgctgattt agaactacct aagcgttaca aagaattaaa ataccttatc
     6541 ttaaggacac caacttacat ggatgatgga aaattacaag tacgagaaga gcagtttgat
     6601 gaaatttttg aggattatta tgataaatta ccagaggaag agaaagttgc tgttgatatt
     6661 atccaagcaa aatttgaagt ttatcaaacc ggagatatta atttcggata tagtatttta
     6721 aaagaatttc taccacagct aaaaagaaaa tctatctata atttaaatga attattactt
     6781 atagatttgt atttgattat tctggtagtt tctcattttt cagatgatat atttgatgta
     6841 cagttttatg aagaaataac agagagcatg ttaaaacaac acaataattt accattggaa
     6901 gatttatttt tactgaataa tatcttatta tcttgtgcgg acacttatat tcgtttgaag
     6961 atgttcggtc gtctaaaaga aacattacaa cttagccact ttataatgtc aactattcaa
     7021 gattttcaaa aaatgcctat gtattgtatg tatgaatgga agctatctat tttttatttg
     7081 aaagatatta accgagcacg gaattacttt gaacagtcta ttttatttac tcaaatgaca
     7141 ggagatacat atttagttca aaaatt
//
LOCUS       DAUCXI010000067         6910 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.067, whole genome shotgun sequence.
ACCESSION   DAUCXI010000067 DAUCXI010000000
VERSION     DAUCXI010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6910
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.067"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            142..915
                     /gene="cfa"
                     /locus_tag="VGY43_001657"
     CDS             142..915
                     /gene="cfa"
                     /locus_tag="VGY43_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HEQ4302818.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTYSVLADDASNPDTILMNNNQA
                     NLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKA
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS"
     gene            complement(1285..2520)
                     /locus_tag="VGY43_001658"
     CDS             complement(1285..2520)
                     /locus_tag="VGY43_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEQ4302819.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLSLSVAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLI
                     HTIKSIFSGQQVDIDPLGAVVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMIPEEELFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLIDANGQ
                     TFNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRRHESWSLLFHQ
                     ITPIAKRQLHHTHYRIVKM"
     gene            complement(2640..3962)
                     /locus_tag="VGY43_001659"
     CDS             complement(2640..3962)
                     /locus_tag="VGY43_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEQ4302820.1"
                     /translation="MIAFVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     regulatory      complement(4090..4176)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            4491..6809
                     /gene="pcrA"
                     /locus_tag="VGY43_001660"
     CDS             4491..6809
                     /gene="pcrA"
                     /locus_tag="VGY43_001660"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEQ4302821.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALSLNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
BASE COUNT         2320 a         1287 c         1355 g         1948 t
ORIGIN      
        1 tgaaatcctc ttattttctg gaaattaaag aaatattgac cttagtaaaa acaagtagta
       61 tgataacgtt ataagcgctt ataaattaat ttaacttcac ttaactattt aaataggttt
      121 attatattca ggaggaataa tatgaaaccc aaacaccttc tctgtctttc aacagttgtt
      181 gctggattag ctttattttc aactatgacg tactcagttt tagctgatga tgcttcaaat
      241 cccgatacta ttttaatgaa taacaaccaa gcgaatcttc aaagagatgc tctagtgcaa
      301 aagcttgatg agggacatca acaattagaa gctattaaac atgaagctaa aggtactgat
      361 attgaggcta ctgttaacaa agctatcgat gctgttgatc acatgaagag ttctatacgc
      421 ttcaatactg aaacgatcta tgattttagt tcaattgggg caagagtaga agcattatca
      481 gatgctatca aagcaatcgt attttccaca acccaattaa ctcataaagt agaaaaagcg
      541 catactgata tggggtttgc tattactaaa ttagtcattc gtattataga tccatttgca
      601 tctgttgacg ctatcaaagc tcaagtacaa gaaattaaag cacttgagga aaaagttatc
      661 aattatcctg atttacagcc aacagaccgt gctactatct atactaaagc taaactaaat
      721 aaagctattt ggaacactcg tttagaaaga gataaaaagg ttttggggat caaaccattt
      781 gacgtttaca atagacttaa caaagctatc acacatgcgg ttggtgtcca actaaatccg
      841 acaaccactg ttcaacaagt tgacgatgaa gttattgctg tgcaaaatgc tttggaaaca
      901 gctcttaagt catagagtgt ataagtaatg tgttgtatag gtagatgatt acattaggat
      961 atagaatagg taaagatttt aaatatctta ccattgtaga gtttgaggtg atgctctcat
     1021 aaacaatgag tcacctgtag ccctttttgc ctttaacatg atgtaccaat ttaaggtatt
     1081 gttcaaccgt cactattgaa tcttgtttaa cctcctaaac taataagatt caatatgaaa
     1141 acgtgtattc ttaaaaaaat ccctatgatc tgtttaaaaa caaattgtag ggattttttt
     1201 aactatttaa cttatcattt tgggactagg aatcgcttta ggaatatcat gaagtatagt
     1261 tatgttataa gagaattaat gtttttacat ttttacaata cgatagtgtg tgtgatgtaa
     1321 ttgtctctta gcgatagggg taatttggtg gaagagtaag gaccaagatt catgacgcct
     1381 ccaaatactg gtacgttgat tgccatttaa ttggtaagtt accaacatcg ttttttgact
     1441 aatggattca atctgaaaat ggttgaagtt acttggataa taaatttctt gattcaaaaa
     1501 ttgttcatag ttaaatgttt ggccattcgc atcaatcagt tggaaagact tagcaatgta
     1561 gtggtcatag tcaggaacct tactcaaaat taatttttcg tagcggtaga gctttttggc
     1621 gacattatca aaaagctctt cttcgggaat catggcaggc tcaacgtgaa tgtcaatgtc
     1681 ataaatagaa aattggtcac tcaataactg ctccactttc tctgtaatag agtgactttc
     1741 atagactgaa agatcaggat tcatttcaag tacaatatca agatagacat tgctaccata
     1801 ggtcctagct cgttgagact taacggcgac aattttaggg atttctaaaa tggctttttc
     1861 gtattttttc aaatgacggc tatcaaatcc atcagataaa ctaaacgaac tttccataaa
     1921 gatatcaaaa gctgttttaa gaataaagaa cgtaatgatc atagcagcta tatgatcgat
     1981 aactggtaaa tgcaaagaag ctgctataat agcaattgat gttccgatag aagtaacagc
     2041 atcagctaga ttatccttag aagcagcgac taaggcactg gattttacac gtttggaaag
     2101 acgtttgtta aagacataga cccctaacat aacaaaagct gaaacgatac cgacaacagc
     2161 cccaagaggg tcaatatcaa cttgctgacc actaaagata cttttaattg tgtgaatcag
     2221 tacttggaaa cctacaagaa acataataaa agaagtgaca aggctggata agtcttcaat
     2281 tttccaatga ccaaatttat gattggcatc ggctggttgg ctagctaagt gaagaccaat
     2341 aagcagggct acatttccca caatatccga taaattgtta aatccatcag caataaggga
     2401 acttgcattt aacaaataac cagctaataa tttggcaaca ctaagcgaca agtagacaat
     2461 aatactaacg attgggcctt ttctggctag ttttaaattt gcaatcggat cctgtgtcat
     2521 aataactcct ttgatttcaa ctttatatta taccataaaa aggggcttaa gaaaaaagcc
     2581 tagcgtcttg aacttggcag aagaagacta ggtataactg ggtagtacta acgtcatgtt
     2641 tacttaataa agtaatgctt ggtttctaaa ataacaactg gcgagagagc taggagggca
     2701 atcaggttag gaagtgccat taaaccattg acaatatcag ccaaaaccca aattagttct
     2761 aacttaagga agcctcctag gcctaccatt aagataaaga caatacggaa gtaggtgaga
     2821 tgtgtaatgc caaagaggaa ttcaaagcag cgttctccat aataactcca tcctaaaatc
     2881 gttgtaaagg cgaagagaac tagggaaaag gttaggccaa aagtccctaa atttccaaac
     2941 acagtggcaa aggcagattg ggtcagagga gccccttcga gctgcccagt ccattggcct
     3001 gttactaaaa tagataggcc ggttagggta cagataataa tcgtatcaat aaaagttcct
     3061 gtcatggaga tcagtccctg ctccacgggt tcattggttt tagctgctgc tgcagcaata
     3121 ggtgcagatc ctagtccaga ctcattggag aagacaccgc gtgcaattcc tttttgaatg
     3181 gcatccttca tgagacttcc agcaaagcct ccaatagcag ctgtcggagt gaaggctgat
     3241 tgaaagacta aacgaataac aggaagtagc tgctggtagt gactaaaaat aactgctaaa
     3301 ctagatagaa tataaaaaat agccataaaa ggaacgactt tttcagccac tttggaaatg
     3361 gaatgaatgc caccaaaaat aatggcagcc acaaagatag ctaaaacaat actgaccatt
     3421 tgtggggata agccaaagct atgacctaaa gacgaggtga tcgagttcac ttgagcaaag
     3481 gttcctattc caaatagggc aactaggatc cctgaacccg caaaaagaat ggctaagggt
     3541 ttccattttg tccccatgcc attaacaata tagtacatag gaccaccaga aatatgaccg
     3601 ttggcatcct ttgtacggta tttaatcgct agtacccctt cagcgtactt agtggccatt
     3661 ccaaaaaaag cggcaaccca catccaaaag agcgctccag gaccaccaga cttgatagca
     3721 gtggcaaccc caacaatgtt accagttccg acagtagcgg caagggcagt tgcaagagca
     3781 gcaaaggatg aaatatctcc atgtccttcg tcatctgaaa aaatgagttt aaaggctctt
     3841 ggtagtttta agatttgaat taatcctaaa cgactggtaa ggtaaatccc cgtcccaacc
     3901 aataaaatta agaggggcgg tccccaaaca aggttatcaa ttaatttaac gaatgctatc
     3961 atctttctct cctaaaagtc atcgaagacg ccaaaagaaa aaagctatct ctttctttga
     4021 gacaacttct gaagcaatga taaaacagca aacacaaaaa agactaagac tgttcttaat
     4081 ggtgtttgta ttttaccttc tgtccttttg cctgagagat tgagcagtat gccttgcccc
     4141 ttcggcgcct aataaggtct ctccagaagt ccgtccatca aacagtcccg ttcaaaaact
     4201 gaacacctga gagtataact ccttcggcga aaaaaattct tctcctgcat gacatcattc
     4261 ggtttattaa attaggacta tcatacctca aaaaacgaat gaagtcaacc aaaatagcaa
     4321 aaaaataagg aatgctttaa gaaatcgcta ttatttttaa atatctgatc ctaaactaga
     4381 aaaaaggaat ctctttactt ttggggtctt ctttgctatt tttcttggaa acatgatata
     4441 attttaaggt tgataaaaga gatgtcactg aacgagatta aggagaaagc atgaatcctt
     4501 tattaaatgg aatgaatgat cggcaggcac aagctgttca aacaactgaa ggccccttat
     4561 tgattatggc gggggctggt tctggtaaaa caagggtact gacccatcgt attgcctatt
     4621 taattgatga aaaatttgtc aatccttgga atattttagc tattaccttt actaataagg
     4681 ctgcgcgtga aatgaaagaa agagccttgt ccttaaatcc agctactaaa gataccttaa
     4741 ttgctacctt tcactccatg tgtgtacgga ttctgcgtcg tgaggctgat cacattggtt
     4801 acaaccgaaa cttcacaatc gtggatccag gtgagcaacg aacgttgatg aagcgcattt
     4861 taaaacaatt aaatatagac cctaaaaagt ggaatgaacg ttctatttta ggaactattt
     4921 caaacgctaa aaatgatttg cttgatgaaa agggatacga ggcacaggct gctgatatgt
     4981 atagtcaaat cgtagcgagg tgttacaaag cttatcagga agaattacga cgtagcgaag
     5041 cacttgactt tgatgattta atcatgatga cgctacgcct gtttgacgct aatcctgacg
     5101 tgttagctta ttaccagcag cgttaccaat acattcatgt ggatgagtac caagatacca
     5161 accatgctca atatcagcta attaaattgc tagcttctcg ctttaaaaat atttgcgttg
     5221 ttggagacgc tgatcagtct atctatggtt ggcggggagc tgacatgcaa aatattcttg
     5281 attttgaaaa agattaccca gatgctaagg tagtgctttt agaagaaaac tatcgctcta
     5341 ccaagaaaat tctgcaagca gctaacgacg tgattaacaa taaccgtaat cgccgtccta
     5401 agaaactttg gacacaaaat gcggatgggg aacaactggt ttattacagg gcaaatgatg
     5461 agcgagatga ggcagtattt gtggcctcaa ccattagcaa tatgagtcaa gagcttggaa
     5521 aaaacttcaa agatttcgct gttttatacc gtaccaatgc ccaatctcgg accattgaag
     5581 aagcactctt aaaatccaat attccttaca ccatggttgg aggcaccaag ttttacagcc
     5641 gtaaagaaat tcgggatttg attgcctatt taaccattgt tgctaaccct gctgataata
     5701 tttcttttga gcggattgtg aatgagccta aacgaggtgt tggtccagga acgcttgata
     5761 aactgcgtca gtttgcctat gagagtgacc agtctttatt agaagcagct tcaaatctat
     5821 tgatgtcccc cttgaaaggt aaagcagcac aagctatcat ggacttggcc aatattctcg
     5881 gtcagctacg tcaagaccta gatcagatga gtatcaccga cttagcagaa gctttgttag
     5941 aaaaaacagg ctatttagat agcttacgcc tgcaaaatac attggaaagc caagcccgta
     6001 tcgaaaatat cgaagaattc ttatctgtta ccaaaaattt tgacgagtca agtgcctctc
     6061 aagaagaaga cgaaaccggt gttgatcgct tgggacgttt tttaaacgat ttagcactga
     6121 ttgctgatac agatgattcc caagcagaag ctgctgaagt aaccttaatg accctacatg
     6181 ctgccaaagg cttggagttc cctgttgttt tcttaattgg tatggaagaa ggtgtcttcc
     6241 ccttatcacg tgcctctgaa gatccagatg aattggaaga agaaagacgt ttagcttatg
     6301 tcggaatcac aagagctgaa gaagttctct ttatgaccaa tgccaacacc agaaccctct
     6361 ttggtaaaag tagttataac cgtccaacac gcttcttgaa agaaatttca gaggaactac
     6421 tctcttataa aggattggca agaccagcac aatcttcatt tggtgtgcgt ttttctactg
     6481 aaacacacac acagtttgga caagggatga gcctatcaga agccttacaa gctcgaaagg
     6541 cccaggctca agtaagacaa tcagcacagc caatgcaggc acatacgata ccatcagctt
     6601 caactagctc agttttaccg tttggttcta atagctctgt agaagaggtc acttggcaga
     6661 ttggcgatat cgctcaccat aaaaaatggg gagacgggac tgtgcttgag gtttcaggct
     6721 ccggaaaaac gatggaattg aaaatcaaat ttccagaagt tggtttaaag aaattactag
     6781 caagtgttgc tcctattgag aaaaaataag aaaaaaatga gcttcctact atataagtga
     6841 gtaggaagct cattttttag atttctgtat catataaaag ttaaaaaatt ttaagtttta
     6901 ggagcatatc
//
LOCUS       DAUCXI010000068         6885 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.068, whole genome shotgun sequence.
ACCESSION   DAUCXI010000068 DAUCXI010000000
VERSION     DAUCXI010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.068"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            1..1785
                     /gene="uvrC"
                     /locus_tag="VGY43_001661"
     CDS             1..1785
                     /gene="uvrC"
                     /locus_tag="VGY43_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEQ4302822.1"
                     /translation="MKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGS
                     HDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFLKITN
                     ESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCFYYHL
                     GQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYR
                     DLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYY
                     NDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKKQLVA
                     LATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGTSPVA
                     AMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDG
                     GVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLH
                     RIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASATSEE
                     IQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            1970..2572
                     /locus_tag="VGY43_001662"
     CDS             1970..2572
                     /locus_tag="VGY43_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEQ4302823.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSTT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            2697..4106
                     /gene="pepV"
                     /locus_tag="VGY43_001663"
     CDS             2697..4106
                     /gene="pepV"
                     /locus_tag="VGY43_001663"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEQ4302824.1"
                     /translation="MTTIDFKAEVDKRKEAMLADLVDLLRINSERDDQLADDKHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNKGAFVLHRFQGGLREN
                     MVPESATAVITAPHDLDVLEAALEQFLSEHGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFIFEGAAKDYLHVAGEVLHEDFAAEKLGLAYTDDRMGALSMNA
                     GVFTFDSQSADNTIALNFRYPKGTDAATLKAGLEKLPGLTKVSLSEHEHTPHYVPMDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(4174..5550)
                     /gene="mnmE"
                     /locus_tag="VGY43_001664"
     CDS             complement(4174..5550)
                     /gene="mnmE"
                     /locus_tag="VGY43_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEQ4302825.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGSIAVTNEIL
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRI
                     ILLNKTDLEQKIELEQLPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     misc_feature    5719..5854
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            5883..6383
                     /locus_tag="VGY43_001665"
     CDS             5883..6383
                     /locus_tag="VGY43_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEQ4302826.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            6448..6813
                     /gene="rplL"
                     /locus_tag="VGY43_001666"
     CDS             6448..6813
                     /gene="rplL"
                     /locus_tag="VGY43_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEQ4302827.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
BASE COUNT         2141 a         1249 c         1465 g         2030 t
ORIGIN      
        1 attaaacata aactagaact cttaccagac agccctggct gttacttaca taaagataaa
       61 gaaggaacta ttatctatgt cggtaaggca aagaatttga aaaaacgcgt ccggtcctat
      121 tttcgtggga gccatgatac caaaacagag ttactagtat ctgagattgt agatttcgaa
      181 tatattgtaa cagagtcaga taccgaagcg cttttgttgg aaattaactt gattcaaaaa
      241 aatatgccta agtacaacat caagttaaaa gatgataaat cttatccctt tctcaaaatc
      301 acaaatgagt cttttcctcg gttagtgatt acaagatata ttaagaaaaa tgatggattg
      361 tactttgggc cctacccaga ttcttacact gctaatgaag ttaaaaagtt attagatagg
      421 atttttccat ttaaaaagtg taaaaatcct atcaataagg tctgttttta ttaccattta
      481 ggccagtgct gtgctcatac catttgtcat acagacaagg cctattggga tcgtttaatt
      541 gatgatgtta agcacttttt aaatggtaaa gatgacaaaa ttattgaaga tcttcgttct
      601 aagatgttag cagcttctga agaaatggca tttgaacgtg ccgctgaata tcgagatttg
      661 atttcaggta ttgccaccat gcgcaccaag cagcgggtga tgagcaagga tttgcaagat
      721 agagatatct ttggctatta tgttgataag ggatggatgt gtgtccaagt tttctttgtg
      781 cgtcaaggga aattaattca gcgtgatgtt aacctttttc cctattataa cgatgcagaa
      841 gaagatttct taacttatat ggggcaattt taccaagata aacagcattt catccctaaa
      901 gaagtcttta ttccagaagc tattgatgaa gaactggtag ccgctattgt gccaaccaaa
      961 atcatcaaac ccaaacgcgg tgaaaaaaaa caactggtag ctttggctac taagaatgct
     1021 cgtgttagtc tgcaacaaaa atttgattta ttagaaaaag atatcaaaaa aacgagtggt
     1081 gctatcgaaa atttaggtca gttacttagg attgacaagc ctgtgcgcat tgaagccttt
     1141 gataattcta acattcaagg gacaagtcca gttgcggcta tggttgtttt tgttgatggc
     1201 aaacctagta agaaagatta tcgtaaattt aagattaaaa cagtggtggg accagatgat
     1261 tatgccagta tgagagaagt gctttttcga aggtacagtc gggtgaaaaa ggagggactg
     1321 caagctccta acttgattat tgttgatgga ggcgttggac aagtcaatgt ggccaaagat
     1381 gtgatagaaa aacaacttgg actcactatt cctgttgcgg gacttcaaaa aaacgataag
     1441 caccagaccc atgatttgct ttttggaaac ccgcttgaag ttgtaccgtt gccgcgccgt
     1501 tctgaagagt ttttcttact gcatcggatt caagacgaag tgcatcgctt tgcagttaca
     1561 tttcatagac aagtgcgacg taaaaattct ttttcatcaa cattagatca tatttcaggg
     1621 cttggcccaa agcgaaaaca gttattacta agacacttta aaaccataac agcgattgca
     1681 tcagctacct ctgaggagat tcaagcttta ggtataccta aaacagtagt tgaagcaata
     1741 cagcaacaga taacagacaa taaaaatgat agatcgtctc cttaaataag tgttatgttt
     1801 tcagtactga tgaggtaaaa aggcgctact tgttacgcac gacatttcag ttcgttattt
     1861 tgaaactttc agaaagttgc gaagtgtagt gagtttatga ttttaaaaac tattttatgg
     1921 taaaataaaa tggtattaaa aaaaacagat ttagatagga agttttgaaa tgaaatttct
     1981 agagttaaac aaaaaacgcc atgccattaa gacctttaat gaccagccag ttgactacga
     2041 ggatttgcga acagccattg agattgcaac cttagcacct agtgccaata acattcaacc
     2101 ttggaaattt gtagtcgttc aagagaaaaa agctgagcta gcaaaagggt tacctctagc
     2161 aaataaagtg caggttgaac aggctcaata tgtagtggcg ctattttcag acactgattt
     2221 agctttacgt tctcgtaaaa ttgcccgtat cggtgtcaaa tcattaccag acgacttaat
     2281 tggttactat atggagactt tgccaccacg ttttgctgct tttaatgagg ttcaaaccgg
     2341 tgagtactta gctattaatg caggcattgt ggctatgaac ttggtgttat ccttgacgga
     2401 tcaaaagatt gcttccaata ttatccttgg ttttgataag tcaacgacca atgagatttt
     2461 agacatcgat ccgcgttttc gtccagaatt attgattact gttggctata gtgacgagaa
     2521 accagaacca agttatcgtt tgcctgttga tgaagtcatc gaaagaagat agagtcagga
     2581 caattagtta aatgtaatgt ccagatgcgc tactgagcga ccactattgt tagactgata
     2641 ctattttggc ttattttaag ttaaacatta tccctaaaac gaataaggag agtataatga
     2701 caaccattga ttttaaagca gaagttgaca aacgtaaaga agctatgcta gcagatttag
     2761 ttgacctatt acgcattaat tcagaacgcg atgaccaatt agctgatgat aaacacccat
     2821 ttggcccagg tccagttaag gctttggagc acttcctcgc aatggctgag cgtgatggct
     2881 acaaaacgcg taatattgat aactatgcag gtgactttga atttggtcaa ggtgatgaag
     2941 tactaggaat ctttggtcac cttgatgttg tgccagctgg tagcggttgg gatacagacc
     3001 cttatgagcc agtgattaaa gacgatcgca tctatgcgcg tgggtcttcg gatgataagg
     3061 gaccaaccat ggcgtgctac tacgctctga aaatcattaa agaattgggt cttcctgtgt
     3121 ctaaaaaagt tcgtttcatt gttggtaccg atgaagaatc tggctggggg gatatggatt
     3181 attactttgc tcataatggc ttgaaaaatc cagattttgg tttctcacca gatgctgaat
     3241 ttccaattat caatggtgag aaaggaaata tcaccgaata cctccatttc gctggtgaca
     3301 acaagggcgc ttttgtgctt catcgcttcc aaggtgggtt gcgtgaaaac atggtaccag
     3361 aatctgcaac agctgtcatt acggcaccgc atgaccttga tgtgctagaa gcagctttgg
     3421 agcaattttt atcagaacat ggtgttaaag gttctatgaa ggctactgat ggtaaaattg
     3481 aagtaactat tattggtaag tctgctcacg ggtcgactcc agaagcgggt gttaatggtg
     3541 ctaccttgtt ggctaaattc ctgaatcaat ttatctttga aggggctgct aaggattatt
     3601 tacatgtggc aggtgaggtg cttcatgaag actttgcggc agaaaaacta ggccttgctt
     3661 atactgatga ccgtatggga gccctgagca tgaacgcagg tgtcttcacc tttgatagtc
     3721 aatcagctga caataccatc gccttgaatt tccgctatcc caaaggaact gatgcggcaa
     3781 ccttaaaagc aggattggaa aaattaccag gattaactaa ggtaagcctt tctgagcatg
     3841 aacatacacc tcattatgtg ccaatggatg atgaattagt agctacctta cttgctgttt
     3901 acgaaaaaca aacaggtctt aaaggctacg aacaagttat cggcggagga acctttggtc
     3961 gtttgctaga acgtggtgtg gcctttggag cgatgttccc aggcgatgaa aacactatgc
     4021 accaagctaa tgaatatatg cctttagaaa atatttatcg ctcagcagct atttatgctg
     4081 aagcaatcta cgaattaatt aaataagatg cttatgacag caaaaagagc tggaacactg
     4141 ttccagctct tttgtgatga ttagagactg ttcttattta ccaagacaaa attggctaaa
     4201 gagttgggta atgagttcat caggagcagc atctcctgtg atttctccga gaatttccca
     4261 agttctggtt aaatcaacct gtagtaaatc aactggcatg ccaagcgcca agccgtcatt
     4321 gacagcttct aaactctgga ctgccttttc aatcaaagaa atgtggcggg catttgacag
     4381 gtaagtggca tcttgctcta ctagtccagc attatcaaag aagagctggt tgatacgatc
     4441 ttcgatcaga ttaatgtttt ggttggttaa aacggaaatg ggaatatagt catctggtaa
     4501 ttgctctaat tcaatctttt gttccaaatc cgttttattc aacaatataa tacggttact
     4561 gtcctgactg agatttaaca aagcccggtc ttggtcggtc agtttttcag aagcattcag
     4621 cacaagaaga acaaggtcag cttcttgaag agctttttta gaccgttcaa ctccgatttg
     4681 ttcaaccaga tcatctgtct cacgaatacc ggccgtatcg acaagtttta gaggaactcc
     4741 cttgatatta acgtattctt caatgacatc tcgggtggtt cctgcaatat cagtcacaat
     4801 agccttgtct tctcgcaaca aattattaag taagcttgac ttaccgacgt ttggacgacc
     4861 aataatagct gttgataagc cctcacgcag aattttaccg cgtttagctg ttcgaaggag
     4921 attttccaaa aggctttgga attcttgtgt tttctcacgt agcagagcag tggtcatttc
     4981 ttccacatcg tcgtattcag ggtagtcaat attaacttcg acttgagcta aggtgttgag
     5041 aatttcttgt cgggtgtcgt tgataagctg ggaaagggag ccatccagtt gcttgactgc
     5101 aatcgtcata gccttgtctg ttttggcacg aataatgtcc atgacagcct cagcttgagt
     5161 caaatcaact cgcccattta agaaggcacg tttggtgaat tcgccaggct ctgccattct
     5221 agcgccttgg cgaatcaata gttgcaagat ttcatttgtc acagcaatac taccgtgcgt
     5281 attgatttca accacatttt cacgggtaaa ggttttgggg gctagcatga ctgacaccat
     5341 aacttcatcg ataatagttc ctgtcttagg atcaatgata tggccatagt taatggtgtg
     5401 tgaggcgact tgctctaagt tctttccctt aaaaacagat tgtgcaatgg caagcgcatc
     5461 tgtccctgat aaacgaacaa tgccaatagc tccttcacca agaggggttg aaatggcggt
     5521 aattgtatca aattctttag ttatactcat gccctctatt ttaaatcaag tcctagtaga
     5581 aagcaaggta ttattttgta tagaaaatag gactagcacc attttgagtt tagctaatac
     5641 taaaaaaata aatgtaaaaa aatcattttt taataatttt tattgacaat agtattataa
     5701 aagaatataa tgatataggt tttgataaaa aactgaccta agacagcagg ggagcatgct
     5761 cataatattc ctgccgaggc acaaaacgtg attaaagaaa ataacgtatt tgtactttcg
     5821 tgtctaggtt taggtgcgat ttttttgtac ctagcccaaa aataaaaacg gaggtaaaac
     5881 taatgagtga agcaattatt gctaaaaaag ctgaacaagt cgaacttatt gctgagaaaa
     5941 tgaaagcagc agcaagtatc gttgttgttg attcacgtgg tcttacagtt gatcaagata
     6001 ctgttcttcg tcgttcactt cgtgaaagtg gcgttgagtt caaagttatc aaaaactcaa
     6061 ttttgactcg tgcagctgaa aaagcaggtc ttgatgagtt gaaagatgta ttcgtaggac
     6121 catctgcagt agcattttct aacgaagatg ttatcgcacc agctaaagtt atcaacgact
     6181 ttactaaaac tgctgacgca cttgaaatca aaggtggtgc aatcgaaggc gctgtttctt
     6241 caaaagaaga aatccaagca cttgcaacat tgccaaaccg cgaaggaatg ctttctatgc
     6301 ttctttctgt acttcaagct ccagtccgca acgttgcata cgctgtcaaa gctgttgcag
     6361 aaaacaaaga aggcgctgct taagacgtct cagagtagct taaggctacg cttaacattt
     6421 taaattaatt atttggagga aatcacaatg gcattgaaca ttgaaaacat tattgctgaa
     6481 attaaagaag cttcaatcct tgagcttaac gatcttgtaa aagctatcga agaagaattt
     6541 ggtgtaactg cagctgctcc tgtagctgct gcagctgctg gtggtgctga agaagctgct
     6601 aaagattcat tcgacgttga attgacatct gctggcgaca aaaaagttgg cgttatcaaa
     6661 gctgttcgtg aaatcacagg tcttggtctt aaagaagcta aaggtcttgt tgatggagca
     6721 cctgctaacg ttaaagaagg cgttgctgct gcagaagctg aagaaatcaa agctaaactt
     6781 gaagaagctg gagcaacaat cactcttaaa taagaggcat ataccaatta gaattcggaa
     6841 tactatagta tcagcctttt agaatcgtga acacatttta gaaac
//
LOCUS       DAUCXI010000069         6691 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.069, whole genome shotgun sequence.
ACCESSION   DAUCXI010000069 DAUCXI010000000
VERSION     DAUCXI010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6691
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.069"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..522
                     /locus_tag="VGY43_001667"
     CDS             <1..522
                     /locus_tag="VGY43_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEQ4302828.1"
                     /translation="ILFMPAFVMNLLILFFRPHITQMAIALIRGQIKEFNKIQVQLFA
                     YLGVFSLIALVGSGLFGIPFLSILYGTNLTDYWVDFMLIMLGGSIGSFATVIDNILTA
                     MRKQQLLLIPYTGGFLISLLITNLFVMKYHILGAALSFLITMLVWLGLSIMIYLFIMN
                     RFKKGRVNATIYD"
     gene            503..1999
                     /locus_tag="VGY43_001668"
     CDS             503..1999
                     /locus_tag="VGY43_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEQ4302829.1"
                     /translation="MQQSMTKVKYLWKENNNYIYSTFLTLLLTVILYANSLNLPLKFI
                     SLLFVVSTLLIVFLPKKLEVATIIFILVFGTISAIISPINDIPDEYVHYSRTVYISEG
                     DINLTNNNKKLRISKDVDKLIKQSGKTFITSNLKATKHSTREYSYPYIKGTNAYYSFS
                     YIPQALGILVGNALDLPILLTYYFGRLCNLISYAMLAFIAIKLSGSFKQVIAVVTLLP
                     MNIYLAASFNQDGFAIGLVLVTIGLFINLLSSKDKSNYNTKFFLYLVLCGLLVLSKFT
                     YFLLVCLPLFIPNEKFGKNTKLVILKKLGGLLLIFLFAAMWFRLYGQVKTPYVADFLK
                     EVNVSQQVKNMLESPIVYSSIIIRHMVINLINMNNIFQFGALSYGITNLFPLYVCFFF
                     FVYISNASKITINIVEKMGIIFVISAIIGATVLAMYLTWTPVGSSTVLGVQSRYLIGI
                     IPLVLLLFSSQQQKFKQIEDILSDKLAIHVSLLFILAMLMSTIFRYYH"
     gene            2093..3316
                     /gene="pepT"
                     /locus_tag="VGY43_001669"
     CDS             2093..3316
                     /gene="pepT"
                     /locus_tag="VGY43_001669"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEQ4302830.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPE
                     MEAIGLQNVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GRDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAHLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            3357..3845
                     /locus_tag="VGY43_001670"
     CDS             3357..3845
                     /locus_tag="VGY43_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEQ4302831.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHVEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(3832..4029)
                     /locus_tag="VGY43_001671"
     CDS             complement(3832..4029)
                     /locus_tag="VGY43_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEQ4302832.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            4078..4554
                     /locus_tag="VGY43_001672"
     CDS             4078..4554
                     /locus_tag="VGY43_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEQ4302833.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTKKASNAKKTSSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            4569..5249
                     /locus_tag="VGY43_001673"
     CDS             4569..5249
                     /locus_tag="VGY43_001673"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEQ4302834.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPIFFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWI
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    5273..5396
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            5411..5941
                     /gene="infC"
                     /locus_tag="VGY43_001674"
     CDS             5411..5941
                     /gene="infC"
                     /locus_tag="VGY43_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEQ4302835.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            5983..6180
                     /gene="rpmI"
                     /locus_tag="VGY43_001675"
     CDS             5983..6180
                     /gene="rpmI"
                     /locus_tag="VGY43_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEQ4302836.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            6239..6598
                     /gene="rplT"
                     /locus_tag="VGY43_001676"
     CDS             6239..6598
                     /gene="rplT"
                     /locus_tag="VGY43_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEQ4302837.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
BASE COUNT         2159 a         1066 c         1289 g         2177 t
ORIGIN      
        1 attttattta tgccagcctt tgttatgaat ttgctaattt tattttttag acctcatatt
       61 acacagatgg ctattgcttt aatcagaggt caaataaaag agtttaataa gatacaagtt
      121 caattgtttg cttatttagg agttttttca ctgatagcgt tagttggaag tggtttgttt
      181 ggtattccct ttttatcaat actatatggt actaacctta cggattattg ggtagatttt
      241 atgttgatta tgctaggagg ctcgattggt agttttgcga cagttatcga taatatctta
      301 accgctatga gaaaacagca acttcttctt attccatata caggaggatt tttgatttcg
      361 ttattaatta ccaatctttt tgttatgaaa tatcatattt taggagctgc tttgagcttt
      421 ttaataacaa tgttggtttg gttgggatta tccattatga tttatctatt tattatgaat
      481 agatttaaga agggaagagt taatgcaaca atctatgact aaagttaaat atctttggaa
      541 agaaaataat aactatattt attcgacttt tttgacatta cttctgacag ttattttata
      601 tgccaatagt ttaaatctac ctttaaaatt tattagtctt ctttttgtgg tgagcacttt
      661 actgatagtg tttttaccaa aaaagttaga ggttgctacg atcattttta ttttagtatt
      721 tggaacgata tctgctatca tatcacctat aaatgatatt cctgatgaat atgttcatta
      781 ttcaaggaca gtttatatct cagaaggtga tattaatctt accaacaata acaaaaagtt
      841 aagaatatcc aaagatgttg ataagcttat taaacagtca ggaaaaacat ttataacatc
      901 aaacttgaaa gcaactaaac acagcacaag agagtatagc tatccttaca tcaaaggaac
      961 taatgcatat tatagttttt cttatatacc acaagctttg ggtattttag taggaaatgc
     1021 gctggattta cctatacttt taacatatta tttcggaaga ttgtgcaacc ttattagcta
     1081 cgctatgctt gcttttatag ctatcaagtt gtctggttct tttaaacaag tgatagctgt
     1141 tgttacttta ctacctatga acatttattt agcagcatct tttaatcaag acggctttgc
     1201 tatcggttta gttttagtaa caattggatt gtttattaac ttgctctcat caaaagataa
     1261 atctaactat aataccaaat tcttccttta tttagttcta tgtgggttac tagttctttc
     1321 aaaattcaca tactttttat tagtatgcct tccattattt attcctaatg aaaaattcgg
     1381 aaaaaatacc aagttagtca tcttgaaaaa attgggagga ctattactca tttttctttt
     1441 tgctgcaatg tggtttagac tttatggaca ggttaaaacc ccatatgtcg cggattttct
     1501 aaaagaagta aacgttagcc agcaagttaa aaatatgcta gaatccccta tagtctatag
     1561 cagtattatt attagacata tggtaattaa tctgattaat atgaataata tttttcagtt
     1621 tggcgcatta agctatggta taacgaacct tttcccgctt tatgtgtgtt tcttcttttt
     1681 tgtttatatt agtaatgcta gtaaaataac tattaatatt gtagaaaaaa tgggtataat
     1741 ctttgttatt tcagcgatta taggtgcaac tgtattagct atgtacctga cttggacacc
     1801 agtagggtcc tcaactgtct taggtgttca aagtcgttat ctgataggaa ttatcccatt
     1861 agtgttgctt ctttttagta gtcaacagca aaagttcaaa caaatagagg atatcctttc
     1921 tgacaaactg gctattcatg tttcgctttt gtttattctc gcaatgttaa tgagtactat
     1981 ttttagatat tatcattaaa ctcttaatta gaggctttaa aaaacttagc ttgaataagt
     2041 attttaaagc cttttatgct ataattaaat tgagaaatta ttgaggtggc ctatgaagta
     2101 cgataacttg ttagatcgat ttataaaata tgtcaaagtg aatacaagaa gcgatccaga
     2161 cagtgagact actcctagta cggagagtca agaagcattt gccttaacga ttttaaagcc
     2221 tgaaatggag gcaattggtt tgcaaaatgt tcattataat ccagttaatg gctatcttat
     2281 tggaactctg cctgccaata atccaacctt gacgcgtaaa attggtttta tagcccatat
     2341 ggatacggct gatttcaatg ctgaaaatgt taatccgcag attattgaca attatcaagg
     2401 aagggacatt acacttggca gttctaatta taagttggat ccaaaagcat ttccaaatct
     2461 taataattat attggtcaaa cattgattac cactgatggg actacacttt taggggcaga
     2521 tgataaatct ggtattgctg aaatcatgac agcaatagaa ttcttgacat cacaaccaca
     2581 aatagagcac tgtgacatta aagtggcttt tggccctgat gaagagattg gggtcggagc
     2641 tgataagttt gaagtggctg attttgaggt ggattttgct tatactatgg atggcggtcc
     2701 tttaggcgaa ttgcaatatg aaactttcag cgctgcagct ctagaagtga cttttttagg
     2761 cagaaatgtt catcctggta cggctaagga tcaaatgatt aatgcccttc agttagcaat
     2821 agattttcat gagaagctac ctgctaaaga gcggcctgaa tacacagatg gttatcaagg
     2881 cttctatcac ttaaccggac taactggaac agttgaagag gcacgcgcat cttacattat
     2941 tcgtgatttt gaagaagcat catttgaagc tagaaaagtg aaagttgaaa atatagctca
     3001 atcgatgaat gctcatctag gaacaaaacg tgtcttggta gagcttaatg accaatacta
     3061 caatatgaaa aaagttatcg aaaaagatat gaccgctatt gagttagcta aagaagtaat
     3121 ggaagagctt gctatcaagc ctgtaatcga acccatacgt ggaggaacag atggctctaa
     3181 aatttcattt atgggtattc ccactcctaa tatttttgca gggggtgaga atatgcacgg
     3241 gcgttttgag tttgttagct tacaaacgat ggagagagct gtcgatgtca ttattggact
     3301 tgtttgcaaa gcctaattat catgtaattg atatttagtg gaaggggctt ataaaaatga
     3361 ttaaactatt tggtaaaata aggtatcact ggcagccaga gttgtcttgg tctattattt
     3421 attggtctat tgcgtttgca cctatttttg taggtttatc tttgttgtat gagcgcactg
     3481 aaatacctag tcgggttttt attctatttg ctatttttgc tgtcctagtt ggcattggat
     3541 tacatcgtta tttcattatt gaaaataatg gtattttaag aatcgtatct tttaaattgt
     3601 ttggtccacg taagctactt atttctacta ttactaagat tgaggtgacc aaatcaacac
     3661 tttgtctgca cgttgaagat aaaagttatc tcttttatat gcgcaaatgg cctaaaaaat
     3721 attttcttga tgccttagcg gttaatccat acttccaagg agaagttata ttaagtgata
     3781 actttattaa attagactat tttgaagttt atcagcatga taaaaaagcc cttactcgag
     3841 ggtaagagct ttagttgggc aagatttgac agctaaaata gcgtccttat ctgaaggaca
     3901 aattgactga cttgtttcag atgagcttga aaatgtgacg ataccattgt catgataatc
     3961 aaaaagtgat gaataggttt ggcatagacc acaagcgatg catttttctg gaatgataga
     4021 tactttcata actattattc taatatgatt ttgttaaatt aacaaggggg gacgatcatg
     4081 gctaaagaac catgggaaga aaaaattgtt gatgatacta tagggacacg aacacgtaaa
     4141 tcaagaaatg ctttcattag cacgccttgg ttgactgctt tattaagtgt attctttgtc
     4201 atcattgttg ctatactttt tattttcttc tatacatcaa atagcggtag taatagacaa
     4261 gctgaaacaa atggttttta tggagcatcc actcataaaa aaacaaagaa agcttctaac
     4321 gctaaaaaaa catcaagtag ttcaacaact acagacacaa caccttctag cgaagaaaca
     4381 cttgcttcta gtgaaggaac tggcgaaacc cttactgtat tggcaggtga gggggcagct
     4441 tctattgcag cccgtgcagg tatttctgtg gagcagctac aagcacttaa tccagagcac
     4501 atgactcaag gatattggta tgccaatcca ggagatcaag tcactattaa ataattgaag
     4561 aggaaaaaat gaaagcaatt aaaattgcga ttgatgggcc agcttcaagt ggaaaaagta
     4621 cagtagccaa gattattgca aaaaatcttg gctatactta tctagatact ggtgctatgt
     4681 atcgctcagc aacttatatc gcactgacac atggctatac gggtaaagaa gtagccctta
     4741 ttttagagga acttgagaaa aatcctattt tctttaaaaa agcaaaagat ggctcccaat
     4801 tagtttttct tggagatgag gacgtgacct tagccattag gcaaaatgat gtgactaaca
     4861 atgtttcttg gatctcagct ttgccagaaa ttagagaaga gctggttcat caacaaagac
     4921 gcattgcaca agctggtggc attatcatgg atggtcgtga cattggaacg gttgttctcc
     4981 cagatgcgga actaaaaatc tttttagtgg cttctgtcga agagcgggca gagcgccgct
     5041 ataaagaaaa cctagaaaaa ggaattgaat cagattttga gacgctaaaa gaagagattg
     5101 cagctcgtga ttacaaggat agtcatcgta aggtttcacc tctaaaagca gctgaagatg
     5161 cccttatttt tgataccaca ggtgtttcta ttgatggtgt ggtgcaattt atccaagaaa
     5221 aagcagaaaa aatagttgac atgtcctaga gcctatgtta gaatattaac aatgagaaaa
     5281 gtagaagtga gagcttctcg ccttgcgact taggttgtct ggccctaaca tgtcgaattc
     5341 ctatggaata ttatgtgtgc gggcttgatt tatcaagtcc gctttcgttt ttctctaaaa
     5401 aaataaagag gtgaagatca tagctaaaaa ggatctattc attaatgatg aaattcgcgt
     5461 tcgcgaagtt cgtctcgttg gtcttgaagg tgaacaatta ggtattaaac cattgtctga
     5521 agcgcaatca ttggctgatg cttcaaatgt tgatttggtt ttaatccagc cacaagctgt
     5581 tcctcctgtt gccaaactta tggactatgg aaagttcaaa tttgagtatc aaaagaaaca
     5641 gaaagaacaa cgtaaaaaac aaagcgttgt gactgtgaaa gaagttcgtc tcagtccagt
     5701 tatcgataaa ggtgactttg aaacaaaact tcgtaacggt cgtaaattcc ttgaaaaagg
     5761 aaataaagtt aaggtttcta ttcgtttcaa aggacgtatg attactcata aagagattgg
     5821 tgccaaggta ctagctgact ttgctgaagc gactcaagat attgctatca ttgagcaacg
     5881 agcaaaaatg gatggacgcc aaatgtttat gcaacttgca ccaatttcag acaagaagta
     5941 attgtcacag tttcattata tctttaagag gagaatacta aaatgccaaa acaaaaaaca
     6001 caccgcgcat cagctaaacg ttttaaacgt acaggttcag gcggtttgaa acgcttccgc
     6061 gcctttacat cacaccgttt ccacggaaaa actaaaaaac aacgtcgtca tcttcgtaaa
     6121 gctggtttgg ttagctcagg agatttcaaa cgtatcaaag caatggttac tggtctttaa
     6181 ttttaaaggc agtagacatt tacgagtatt ataagaatta tttgaaggag aactattaat
     6241 ggcacgtgtt aaaggtggcg ttgtttcacg caaacgtcgt aaacgtattt taaaattagc
     6301 taaaggttac tatggagcaa aacacatctt gttccgtact gcaaaagagc aagtgatgaa
     6361 ctcttactac tatgcatacc gtgaccgccg tcagaaaaaa cgtgatttcc gtaaattatg
     6421 gatcactcgt atcaatgcgg ctgctcgtat gaacggtttg tcatactcac aattgatgca
     6481 cggtttgaaa cttgctgaaa tcgaagtaaa ccgtaaaatg cttgctgatt tagcagtagc
     6541 tgatgcagca gctttcacag ctcttgcaga tgcagccaaa gcaaaacttg gcaaataaga
     6601 aacgctatac ctagaaaata actttttatt acctatagaa agttataaag aaacaaaaat
     6661 gaaggagacg atggacgtct tctttttatt a
//
LOCUS       DAUCXI010000070         6665 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.070, whole genome shotgun sequence.
ACCESSION   DAUCXI010000070 DAUCXI010000000
VERSION     DAUCXI010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6665
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.070"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(280..588)
                     /locus_tag="VGY43_001677"
     CDS             complement(280..588)
                     /locus_tag="VGY43_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302838.1"
                     /translation="MTRLISQQILSEYVKSLEVEADKVVIPGQNTPVFSWDRDGNLSI
                     DTPLLKVRGESLATQADLTTISLTPGPKGELWQTSVERLDIKVDKHISLTFKNGVRID
                     "
     gene            complement(654..1105)
                     /locus_tag="VGY43_001678"
                     /pseudo
     CDS             complement(654..1105)
                     /locus_tag="VGY43_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407405.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            complement(1210..1430)
                     /locus_tag="VGY43_001679"
                     /pseudo
     CDS             complement(1210..1430)
                     /locus_tag="VGY43_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1449..1754)
                     /locus_tag="VGY43_001680"
     CDS             complement(1449..1754)
                     /locus_tag="VGY43_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEQ4302839.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADNLLERLSQGM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            complement(1754..2056)
                     /locus_tag="VGY43_001681"
     CDS             complement(1754..2056)
                     /locus_tag="VGY43_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEQ4302840.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLITSFEDAKTGNRQDVREFLFQLKENA"
     gene            complement(2111..2287)
                     /locus_tag="VGY43_001682"
     CDS             complement(2111..2287)
                     /locus_tag="VGY43_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEQ4302841.1"
                     /translation="MGQNVVMRQAPAGNIKPDKEKSVEKIDGIVSLILGLDRCIRRQG
                     DEASVYDERGILSF"
     gene            2303..3196
                     /locus_tag="VGY43_001683"
     CDS             2303..3196
                     /locus_tag="VGY43_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302842.1"
                     /translation="MTTMLDFPFHHEFIESLGRWTHILITLPKRHHGQVDTAIPRYLL
                     VTIREKTGIVKLTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPGCDRPLILTSGN
                     LAAENYEVSAIEKDKDAEPLNLIALCPDCFLTYQADSRKKIVTALKNVKKILVSAHNS
                     QQAISDMKLDSGIVSVLTSLNKLKCDEYDISYDSKQLTDKISPENNRTLYQLVKNPVI
                     DNYLTIQKIIVNLDKQGKIDYEEIQYQTRSMYKKLKAAKHNNLAIFNTISEKLHKATL
                     QDIYFCQMIVSYFIQKCEVLE"
     gene            3196..3420
                     /locus_tag="VGY43_001684"
     CDS             3196..3420
                     /locus_tag="VGY43_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302843.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSGNSNVKDIFHAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            3411..5068
                     /locus_tag="VGY43_001685"
                     /pseudo
     CDS             3411..5068
                     /locus_tag="VGY43_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904398.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
     gene            5058..5267
                     /locus_tag="VGY43_001686"
     CDS             5058..5267
                     /locus_tag="VGY43_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ4302844.1"
                     /translation="MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLEICIALDCKIEDIVEIVDNNI"
     gene            complement(5369..6544)
                     /locus_tag="VGY43_001687"
     CDS             complement(5369..6544)
                     /locus_tag="VGY43_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ4302845.1"
                     /translation="MYSKVIYRIGDVMFDFANNTFLAGLNPASLSLVAVYQFLESVIG
                     VLFNLFGGVIADSFKRKKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNVILAFMS
                     AFSSPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKLLGIHGVLLLD
                     GLSFLIAALLISFILPVNDEVVIKEKVTIREIFNDLKIGFKYVYSHKSIFIITVLSAL
                     VNFFLAAYNLLLPYSNQMFGEISAGLYGTFLTAEAIGGFIGAILSGFVNKELSSMRLI
                     LFLSLSGLMLMLAPPFYIMFHNAIILALSPALFSLFLSIFNIQFFSLVQKDVDNDFLG
                     RVFGIIFTITILFMPIGTGFFSVALNPNNSFNLFIIGSCITILSLVFRILFKKYNIR"
BASE COUNT         2268 a         1329 c         1078 g         1990 t
ORIGIN      
        1 tttttaacgt tattattttc aaatactcta cataaaatta ccctagagta ttaaaactcc
       61 tagtcccttt gtttcaagct atttagaact tttattgtat tatccacttt attcctattt
      121 ctgttgctat tagtttaacc atgaaatcta acctttaccc tttttaggga gtgcaaaatc
      181 caaatgaatc gtgcatctca actcccaata taacttcttt cattatacca cagataaact
      241 aaaaaaggac gtgccgaatt gatacgccct tgccttttat caatcaatcc gtacgccatt
      301 tttgaaggtt aggctgatgt gcttgtctac ttttatatcc aacctttcaa cacttgtctg
      361 ccagagttct ccctttggac caggagttaa agagatggtt gtaaggtcag cttgtgtcgc
      421 tagactttcc cctctcacct ttaggagcgg tgtgtcaatg gaaagattcc catccctatc
      481 ccaactaaag actggagtat tctgtcctgg aataacgacc ttatcagctt caacttctag
      541 gctcttcaca tactctgata gaatctgttg ggagataagc cttgtcatcc atgctgaact
      601 agagacggtc aactcatcaa tcttagcttt ttgaagtgct gcaactcgtg cttctaaggc
      661 atccgttgcc agataatcaa gagcagcttt cttatcagaa cgctcgcctt ctgctttagc
      721 agtagcgata ccataccact tttatctcgt ataatctgca cataggcatt tccccatatc
      781 aaaagatggc tcatgattgc ctctcgaaag ataaaggagg acatctctgg attgggttca
      841 tcatgaagaa gaaagtacag tgggtggtcc agctttttct ccttcccatt ttctgtccgt
      901 tcatagatgt gaataggaaa tgacgccacc gcttcagcaa gaatacgcac acaggcatag
      961 actgccgtcg tgtgcatagt cttaaactca tccacattct cgccactagt cgtgcgacca
     1021 aagaggtagg aaaagtcctg accttcataa ctgttttgag gcttatctct agcccttttt
     1081 ttctaattaa atcaagtagt cccataagcc ctccttattt tggggtacaa aaaaagcacc
     1141 tcctttgaag tgctttcggt atatttcttt caaagtaatc aacagtcttt cttacaaaac
     1201 ctagtattct cattctgtca attccttaaa tgcgtcaaga tgtcgtgata atactgaagt
     1261 cgcaatctca tctaaccttg cttgttcaac aactgttgtc atctgctcat caccaaagtt
     1321 ccatcagttg atttataaag gttaaactcc tgattctctt gaatgccaaa taggtcaggt
     1381 atcggaggat agatgtcatc accaatttgt atcgtcttta cgagttccat acatcactct
     1441 cccttacttt accaattatt catatgacgt gatccataga cgaccgcaac aattataact
     1501 tcatcttcca gaacatgata tacaatgcga tattttttga caatcagttg tctgaaggta
     1561 tagccttttc caatcagatc ctcaatgatg gcacaacgtt caggaaaaat ggatagtgat
     1621 aacattcctt gggataacct ctcaagaaga ttatccgctg cctgtggtgc acagagttca
     1681 tcacgaacat agtgatagat gctcagcaaa tctgctttag catcatccga catggtgacc
     1741 tgatattctt tcattaagca ttttccttca attgaaatag aaattctctg acatcctgac
     1801 ggttgccagt tttcgcatct tcaaagctgg tgataagctt atcataaaac ttctcctgac
     1861 tcatgtaatc aacattaact cgttgaggcg cttcaggtag agaaacatca aatgggatgc
     1921 ccccagtcaa aataatctga ttcaaaaaca tatcaatcgc agttgacata ggaataccta
     1981 agcgtttcaa aatatcatct gccgcacttt ttactgaatc atcaactcgt aaattcaaag
     2041 ttcccgtttt agccatggtt atcctccttt tttgtaacga cattgtatca catttttgga
     2101 gttgactcaa ctaaaaactc aatatccctc gctcatcata gacgctagct tcatcacctt
     2161 ggcggcgaat gcaacggtca agccccagga taagacttac aataccgtca atcttctcaa
     2221 cagatttttc cttatctggc ttgatgttgc ctgcaggagc ttgtcgcatc accacgtttt
     2281 gtcccatcca tttaacgact ggatgaccac catgttagat tttcccttcc atcatgagtt
     2341 tatagagtcc cttggacggt ggactcatat ccttataacc ctgcccaaaa ggcaccatgg
     2401 tcaagtcgac accgcaattc caaggtatct tctggtaacc atcagagaga agacagggat
     2461 tgtaaagtta accactgtgc aaaatacagc gttcactacc cagtcgaatc aactcaaaaa
     2521 acaatacggg cagttcttgt taacagaatc taataactgt tgtgcatgcc caggctgtga
     2581 tagaccactc attctaacca gtggcaactt agcagcagaa aattacgagg tttcagccat
     2641 tgaaaaagat aaggacgctg aaccactgaa tctgatagcc ctctgcccag attgtttttt
     2701 aacctatcaa gcagatagtc gcaaaaaaat tgtaacagct ctaaaaaatg ttaaaaagat
     2761 tctagtctct gcacataaca gccaacaagc gatttctgat atgaagttag acagtggaat
     2821 tgtttcagtt ttgactagtc tcaataaact aaaatgtgat gaatatgata tctcctatga
     2881 ctcgaagcaa ttgactgata agatatcacc tgagaacaat cgtacgcttt atcaattggt
     2941 taaaaaccca gttattgata actacttaac cattcaaaaa atcatcgtaa atttggacaa
     3001 acaaggaaaa attgattacg aggaaatcca atatcaaacg cgatcgatgt ataaaaagtt
     3061 aaaagcagcc aagcataata atctggctat tttcaatact atttcggaaa aactccataa
     3121 agctacacta caggacatct acttctgtca gatgattgtc tcttacttta tccaaaaatg
     3181 cgaggtactt gaataatgca attaccaaat aaactttact cctatcaaaa aagcaccctg
     3241 gcctatttac ctagagtgct aaatgaaatc aaaagtggaa actcaaacgt caaagatatc
     3301 tttcacgcta tctcagaaga gttggatgat cctacagatt ttctatccat aatggattgc
     3361 ttgtatgcat tgaacgctat tgaaatgtct aatgaaggag aagtaaaatt atgcttatag
     3421 aaatgtggtc tccagtattt aagaaacacg gagaaattcg ggaaccaatc tgcttccacc
     3481 atgggttaaa cgtgattatg gggatggatt tagctgataa ctctatcggc aaatcctcct
     3541 cactattagc cattgatttc atctttggag gtaatagcta tctaaaatca attgcggtta
     3601 aaaaattagg tgatcatcct atctacttct gctttcaatt tgagaaaaag ttttattttt
     3661 caagagatgc ggccaaccca gatatcattc tagtgtgtga caagagctac tctccaaccg
     3721 gtgaaacaat ggacctagga atttttctta acaaacttaa gaaacgatat catttagatt
     3781 ctccagagct atcattccga ttagctatga gtggcttctt taggattgca ggaaaaagta
     3841 atcaaaatac cgatttcccc ttacaagttt attcgagcca aaaatcttct gaatctatta
     3901 ctactctcat ccaactgttt aatttgtatg ataacattgc acgatacaaa gaacgtctga
     3961 aagataagag cgaccagtta acaacttttc gtaatgctcg aaagtatgcc ttcatctcca
     4021 acctggttgg cggtaaaaag caatttgaag cgaatgtctc agaaataaaa agattggaat
     4081 atgatatagc acatctccaa gatactcatc aagataaaat tgactctgat gatattgaga
     4141 aaaatcaaca aaaactccaa cttagaaata ctaagctgga gttagaaagc agtcttcggg
     4201 acaagcaaag acgtcttaag ctattggaca tcagtatcga atttggctta tatcctactg
     4261 aatctgactt aacagagctt caaaaatact tcccagatac taatctcaaa aaattatatg
     4321 aagttgaagc ttaccacaaa aaattggcaa ctattttaga ttccgaattc tcaactgaac
     4381 gtgaatccct aatagctgag atcgatgaat tagagagtca attaacaatt ctaaaccaag
     4441 aacttcaaga actaggaaac atcccaaatc tttcaagtga gtacttagaa aactactcta
     4501 aactaacagc tacaatcaat gcactaaaag aacaaaacga ggcctactta aaggagtctg
     4561 gtctatccaa agaaaaatca gaagcagacg ctgacttgaa acgcagtaca gaagatatcc
     4621 ttctagatct agaagtaaaa atcaacagta agatgcgtga attcaataac attctatatc
     4681 cagatattcg caaagctcct caattaacct caatgctcac aatagctact ccttctatac
     4741 accagatgat gatggtacag gaactaagtt caaagggatg attgtattcg acttagtaat
     4801 gctctacctt actaatctgc cagcactcgc acacgattca ttactcttga gtaatgttag
     4861 ctaccaagcg actgaagcac ttttgaagct gtatgaccag tcaaagtcat tgaacaaaca
     4921 agtcttttta gccttcgata aagccagctc ttattctcca gatgctaatc aactcttgtc
     4981 agaaaatacg gtattgagac tctctagtaa cggaaatgaa ctctacggta tttcatggaa
     5041 caaaggagaa aactcagatg agatttagtt acaataaatt atggaaactt cttattgata
     5101 aaggttggac caaaacaaag ctcaggcaag aagctgggat tagttcttcc acgatcgcaa
     5161 aattgggaaa aggagaaaat atcactactg atattttatt ggaaatttgt attgcacttg
     5221 attgtaagat tgaagatata gtagaaattg tagataataa tatctagaaa taaaaaaagc
     5281 actgagttga taagatgtgt aagtcagatc aacttagtgc ctttactttg aaaaaaataa
     5341 ttttctcaat aatacttagt actaactgtt aacgaatatt atacttttta aataatattc
     5401 taaatactaa tgacaatata gtaatgcacg aaccaataat aaaaagatta aagctattgt
     5461 taggatttaa tgccaccgag aaaaagccag tcccaatagg cataaaaaga atagttattg
     5521 taaagataat accaaacact ctccctaaaa aatcgttatc aacatctttc tggacaagag
     5581 aaaaaaattg aatattaaag atggaaagaa ataaactgaa taaagctggt gacaaagcta
     5641 aaataattgc attatgaaac ataatataaa atgggggagc taacattaac atcagtcctg
     5701 ataaagatag aaacaatatc aatctcatac ttgataattc tttattcaca aaaccactta
     5761 atattgcccc aataaatcca ccaattgctt ctgctgttaa aaaagtgcca taaagtccag
     5821 ctgaaatttc tccaaacatt tgattactat agggcaacaa taaattataa gcggctagaa
     5881 aaaaattaac aagtgcagaa agaacggtaa taataaagat ggacttatgg ctgtaaacat
     5941 atttaaatcc tatttttaaa tcgttaaata tttctctgat tgtcaccttc tcctttatca
     6001 ccacttcgtc attaacaggt aaaataaagg aaattagtaa agcagctatt agaaatgata
     6061 gtccatccaa tagtaataca ccgtgtatac caagtagctt atataagaaa attgctacca
     6121 taggaactgt tactttgatt acagtacttg ttgtctctag caatgaatta agttgtgata
     6181 tactatcttt tttaacaatt tcttttgtaa atgctttata ggatggacta gaaaaagcac
     6241 tcataaatgc caagataaca ttagttagta caatggcata aaccaaccat tgctcttttg
     6301 ttaggaacga gagtactaag caagctgtgc cacataagat atttgtagta ataataattt
     6361 ttttccgctt gaaactgtct gcaatgactc caccaaataa attaaataga acacctatga
     6421 cactttctag aaactgatat actgcaacta atgatagaga cgctggatta agcccagcaa
     6481 gaaaagtatt gttagcaaaa tcaaacataa catcgccaat tcgatatata actttactat
     6541 acactaaata ttgaatattt ttttcctatt gttcatttta aagaccttta aaattttcag
     6601 atataataac ttttaactga atttattact taaaaatatt ttttcgcaaa aatgtttttg
     6661 ttaat
//
LOCUS       DAUCXI010000071         6017 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.071, whole genome shotgun sequence.
ACCESSION   DAUCXI010000071 DAUCXI010000000
VERSION     DAUCXI010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6017
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.071"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            66..686
                     /locus_tag="VGY43_001688"
                     /pseudo
     CDS             66..686
                     /locus_tag="VGY43_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein"
     gene            866..1176
                     /locus_tag="VGY43_001689"
                     /pseudo
     CDS             866..1176
                     /locus_tag="VGY43_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670034.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            1174..1458
                     /locus_tag="VGY43_001690"
                     /pseudo
     CDS             1174..1458
                     /locus_tag="VGY43_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            1507..1716
                     /locus_tag="VGY43_001691"
     CDS             1507..1716
                     /locus_tag="VGY43_001691"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302846.1"
                     /translation="MTDRVMKKPIRGRQLSKRDLYDEEFFRTHFAKIEIESRLKFLFN
                     RANSLEELLLKAKEVNLTIDLKQKM"
     gene            1981..2678
                     /locus_tag="VGY43_001692"
                     /pseudo
     CDS             1981..2678
                     /locus_tag="VGY43_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
     gene            2829..3515
                     /locus_tag="VGY43_001693"
     CDS             2829..3515
                     /locus_tag="VGY43_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEQ4302847.1"
                     /translation="MYKILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFK
                     GYDLILLDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKP
                     FSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYR
                     EYEILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEYIYQIRMKFSSFGINPIKT
                     IRGIGYKWDV"
     gene            3508..4854
                     /locus_tag="VGY43_001694"
     CDS             3508..4854
                     /locus_tag="VGY43_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEQ4302848.1"
                     /translation="MFKKYSIKNRVWRAVVEIVFGVCITVLMIAIISLSFSKLNIVTS
                     HNVGEEFYIKDKQSIKQLNNYMKTLGLDYVVFDRKTDKAMEGKYLSKEFSLFNEVAEE
                     KNNLTFNSVHYDLYTNINYNIVIRYNEIPEFSNHYLRNVSYNMLTFYILGIGTSISIV
                     VALTRFVKEISLNFKEIKKLANKMGIEVLSENENYSKIIEFDDILRTLHIKGDNLKSL
                     IEREILEKQDLSFQIAALSHDIKTPLTVLKGNLELLELTTLNKNQEGYIVSMNNSISV
                     FEGYFNSLISYTRMLSEDRSVKLILVEELLSELHFEVDDLLNINNIEFSICNRLIITS
                     FYGDEENLIRALSNLLVNAIRFMPVLDKKIEVILSESGEQIHFEIWNNGERFSDSTLK
                     KGDKLFYTEDYSRGNKHYGIGLAFVKGVAIKHGGNLQLNNPARGGASAIISIKKKI"
     gene            5011..5151
                     /locus_tag="VGY43_001695"
     CDS             5011..5151
                     /locus_tag="VGY43_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HEQ4302849.1"
                     /translation="MTNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTT
                     VK"
     gene            5266..>6017
                     /locus_tag="VGY43_001696"
     CDS             5266..>6017
                     /locus_tag="VGY43_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302850.1"
                     /translation="MIKAQLKNLIKTIHLVKEAGFSLLVFSIAISLFQGILPIFSMLL
                     VQKMLNIITTDIKNFHTLMIAFISYIALTLLTIIIGEVDSYIDTKLQILLHYKMNHLV
                     MQKTVKLTLAEFETPEIYDDITRIQNQISYKPFQIYKSIISVLSSLVSLISSFVILLN
                     WKISIFPLLLILPIVSIYIYLKIGKNEFEILYKRSSDERANWYISHLLTHDFAVKELR
                     LGTLESYFLKKYDKNNQLFINQENSINRSKMK"
BASE COUNT         2151 a          797 c         1147 g         1922 t
ORIGIN      
        1 atttttttat gttcaggagg aaaatcatgc aaatgaatga acagtcatca cgacaaatgg
       61 tgattgccat ctatctcatt tattccaact caaaatgata gtactccttg gctgttccaa
      121 gtcgaaattg ttagtgatta agaaaaccta cgagactatg gtttgatcga tgaaggccag
      181 cagtctccca gtgaaaaagg gcgtttggct aataagattt atttaggaaa gttggaacat
      241 gattccaccc cagtcttaag ttcagacggg ggtagtctaa aaaaacacgg gaccagtctc
      301 aaaaacagac aagccccgtg ttaaattcag cccctagtga gactgaaaag agtgaaactg
      361 aaggtagtga aactaaagag agtaatttag tcattgagga cgaggaggaa agaaaggagt
      421 gcactagtgt gaaaaagact gagggtcact ttacccgtca agttgatcag gtcaccaaat
      481 atgacaaaga ttatatttgg agtttggttc attcccaatt acgtgaaggt ggtttatcac
      541 aagctgctag tgacttagtc atgagctatt ttgaagaacg ctatgcttat gcgctggaac
      601 acatacggtt cgcaagaaca gctgaagcta ttgcggaata tgtctttaat ggtgtcttat
      661 ccgaatggac caagcaacta aggtgacaag aagcgaagtg aggtgagtaa gatgttttgg
      721 tggctattat taggtgtttg gggtctaagg acaatttggt tgattattga agttatcact
      781 gcaccagaaa tggaagatta tagttgagta aggacgttac ataagcagta aggtcctttt
      841 attttgtcag aaaggaatga gagatatgaa gtttttagat ttgtttgcag gaattggagg
      901 ctttcgattg ggtttaatta atcagtgcca tgagtgtatt ggcttttgtg agattgataa
      961 gtttgcgagg caatcttaca aagccatcta tgagaccgaa ggagaaatag aatttcatga
     1021 cattagacaa gtcacagacc aagactttag acaacttaga gggcaagtgg atatcatctg
     1081 cggtggtttt tcccttgtca agcattttca ctcgcaggca gacgactggg atttgagggc
     1141 actaggagaa ctctcttctt tgagattact cgagcgactc atacagacaa agatcatatt
     1201 cataatcaca tcttaatcaa cgccattgac tgtaattcag ataaaaagtt gatatggaat
     1261 tatgccttgg aacgaaacct tcgtatgatt tcagaccgca tttctaaaat ggctggggcg
     1321 aaaattattg aaaagcattt ctcttaccgt gactatcaaa aatatagagc gactagccat
     1381 aagtttgaac taaagcaacg tctttatttt ttgatgcagc agtcaaagtt ctttgatgat
     1441 tttttagaaa aagcagagta attacatgtt catattgatt ttagtcagaa gcatagcaga
     1501 ttcatgatga cggatcgagt aatgaaaaaa ccaattcgag gtcgtcaact cagtaaacga
     1561 gatttatatg atgaagaatt ttttcgtaca cattttgcca agatagaaat tgaaagtcga
     1621 ttaaaatttt tgtttaaccg tgccaattca ttagaggagc tactattaaa agcaaaagaa
     1681 gtgaatctaa ccattgactt aaaacaaaaa atgtaacttt tatcctagaa gaagatactc
     1741 aaaagataag tttaggtcat aaaaaaataa gcgataagaa attatatgat gtcaattttt
     1801 tcaagattac tttaaaaata aggaagtcgg tgtttcagat cgattagaaa gtctacagaa
     1861 acagtacatg cttttcaaga agaatgagat aaagaggagg tatccactga agagagtaag
     1921 gaagtcttca agaaatacaa ggggcaacga gatgccatcc atgagtttga agttgaactt
     1981 gtggaacatc aaattgagag gttaattgct gaggacattt atatcaaggt gtcttttggt
     2041 gtaaagcaga gtggtcttat tttcattcct aactatcaat tggatattag gaaagaagaa
     2101 aatcataaaa aatataaagt ctatattcgt gagaccgcac aattcttcat ttacaacaag
     2161 gaggcgtcta aacttaatcg ctatgtgcga gggcgtgagc tcatttacca gttaaccaat
     2221 gatagcaaga gtattccaaa aagaagacga ccaaaaccat tgatacactt aagaaaaaga
     2281 ttgaagaaat aagtctcctc attgagttag atacggagaa taagccttat caagatatta
     2341 aagatgacat tgttaaagat atggctcaat tagatttgac cattacagag ttgcaggacc
     2401 atattgctca tctcaataag gttgcggagg tcttgcttaa tctgaacaac aacgatatag
     2461 agaaccgccg tttggccaga tatgactatg ccaagatgaa cttgactgca gctataaaaa
     2521 tagaagaagt tgagaaagag attgaaactt ctcaaaatga acttaatata tccatagatg
     2581 agtatgaata tctagtaaga aggttggaaa agtttggaga gatcttgagt gatagcaaaa
     2641 ttatcgatac ttctcgaaat gaaatacaat gggagtaatt atgatataat ttgggtggta
     2701 gcaattttta tatcagatat taaaatctag ttgatgtttc gtaaataact atattaaaga
     2761 aatgattcct gccgcttaca ttaagaatag tttatttgta agtatttcat tatttaaaag
     2821 gggtaataat gtataagatt ttagccatag atgatgataa agaaattctg aagcttatga
     2881 agactgcttt ggagattgaa aattatcatg ttataacctg tcaagagata gaattaccaa
     2941 tagtttttga tgattttaaa ggatatgatt tgatcttatt ggatatcatg atgcctaata
     3001 taagtggaac tgagttttgt tataaaattc gggaagaagt tcattctcca attatttttg
     3061 ttagcgcttt agatggcgat aatgaaattg tccaagcttt aaatataggg ggagacgatt
     3121 ttattgtgaa accatttagc ttaaaacaat tcgtagctaa agttaactct catttgaaga
     3181 gagaagagag agcaaagata aagaatgagg ctgaggagag agtgaagcgc agttttccac
     3241 ctatagaaat ctatctagag gaacgtatgt tatatattga taaacagccg ttattcctga
     3301 cttatagaga gtacgaaatt ttagaattac tgtcacgtca tccgtataaa gttttcacaa
     3361 aagaagagat atatgaacaa gtatatagcg atgaagcttc agcattgttt cattctattt
     3421 cagaatatat ctatcagatt agaatgaaat tttcaagttt tggaattaat ccaataaaaa
     3481 ctattcgcgg gattggttat aaatgggatg tttaaaaaat attcaataaa aaatcgtgtt
     3541 tggcgcgccg tcgttgaaat tgtctttgga gtttgtatca ctgttttaat gattgcgata
     3601 atatcgcttt ctttttcaaa gttaaatata gtgacatctc ataatgtggg agaagaattt
     3661 tatattaaag ataaacagtc aatcaaacag ttgaacaatt atatgaagac attgggatta
     3721 gattatgttg tttttgatag aaaaacagat aaagctatgg aaggaaaata tttatctaaa
     3781 gaattttctt tatttaacga agttgcagaa gaaaaaaata atctgacttt taattctgta
     3841 cattatgatt tatatactaa tatcaattat aatattgtca taagatataa tgagataccg
     3901 gagttttcta accattacct tagaaatgtt tcatataaca tgttgacatt ttatattctg
     3961 ggaataggaa cgagtatcag cattgtagtt gctttaacac ggtttgtaaa agaaatttct
     4021 ttgaatttca aggaaatcaa gaagttagca aataaaatgg ggatagaagt cctttctgaa
     4081 aatgaaaatt attctaaaat aatcgagttt gatgatatac ttagaacttt acatattaaa
     4141 ggtgataatt tgaaaagttt gattgagcga gaaatattgg aaaagcaaga tctatccttt
     4201 caaattgcag cactttcgca tgatataaaa acacctttaa cggttttgaa aggaaatctt
     4261 gagttattag aattgactac tttaaataaa aatcaggaag gttatattgt atctatgaac
     4321 aatagtattt ctgtttttga aggctatttc aattctttaa tatcttatac acgcatgctt
     4381 tcagaggata gatcagtgaa actaatttta gttgaggagc tattaagtga gttacatttt
     4441 gaagtcgatg acttattgaa tatcaataat attgaatttt ctatttgtaa tagacttatt
     4501 atcacttctt tttatggaga tgaggaaaat ctgataagag ctctttctaa ccttttagtt
     4561 aatgcaataa gatttatgcc cgtattagat aaaaaaatcg aagttatact gtctgagtca
     4621 ggagagcaaa ttcattttga aatatggaat aatggtgagc gtttcagtga tagtacactg
     4681 aaaaagggag ataaattatt ttacacggaa gattatagca gaggtaacaa acattatgga
     4741 atcggtttgg catttgttaa aggcgttgct atcaaacacg gtgggaatct tcaattgaat
     4801 aatccagcta gaggaggtgc tagcgccata atctcgataa aaaagaaaat ttaatagatt
     4861 tgattgaaac tggagtattt caggcaaaaa atcgtaaatt ttggtgattt ttggctaaaa
     4921 tacttttttt ctgaacaaat tctgaacttg gggtgtcata ataatcatgt aaatatatcg
     4981 gatgcaaaaa cgtaagagag gaactagaaa atgactaaca caattaaaga ctttgatctc
     5041 gatttgaaaa caaataaaaa agacactgct acaccttatg ttggtagccg ttacctatgt
     5101 acccctggtt cttgttggaa attagtttgc tttacaacaa ctgttaaata ataaagttat
     5161 cattatcatc aacattataa tttcaaataa tttgatatat ttataaattt aggggagtag
     5221 actgatttta gtttgctcct ttattagtag ataaggaagt tatacatgat taaagctcag
     5281 ctaaagaatc taataaaaac aattcatctc gtaaaagagg ctggtttctc cctactggtg
     5341 ttctcaattg ctattagctt atttcaaggg attttaccca tttttagtat gctactagtt
     5401 caaaaaatgt taaacattat aacgactgat ataaaaaatt ttcacacatt gatgattgct
     5461 tttatctcat atattgcttt aacattattg acaattataa taggagaagt tgatagttat
     5521 attgatacta aattacagat acttcttcac tataagatga accatttagt tatgcagaaa
     5581 actgtaaagt taacattggc tgaatttgag acaccagaaa tctatgatga tatcactcgc
     5641 atacaaaatc aaatatctta taaacctttt caaatatata agtcaattat ttctgtatta
     5701 tcttcgttag tatcattaat ttcctcattt gttattttat taaattggaa gatatcaatt
     5761 tttccacttt tacttatcct tcctatcgtt tctatatata tctacttgaa aattggtaaa
     5821 aatgaatttg agatactata taaaaggagt agcgatgaga gagcaaattg gtatattagt
     5881 catcttttaa cacatgattt tgctgtcaag gagttgaggt taggtacgtt agaaagttat
     5941 tttctaaaaa aatatgataa aaataatcaa ttatttatta atcaggaaaa tagtataaat
     6001 agatctaaaa tgaaata
//
LOCUS       DAUCXI010000072         5945 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.072, whole genome shotgun sequence.
ACCESSION   DAUCXI010000072 DAUCXI010000000
VERSION     DAUCXI010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5945
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.072"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..1134)
                     /locus_tag="VGY43_001697"
     CDS             complement(<1..1134)
                     /locus_tag="VGY43_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEQ4302851.1"
                     /translation="MVIFDLKHVQTLHSLSQLSISVMSQDKALIQVYGNDDYLLCYYQ
                     FLKHLAIPQAAQDVIFYEGLFEESFMIFPLCHYIIAIGPFYPYSLNKDYQEQLANNFL
                     KHSSHRSKEELLSYMALVPHFPINNVRNLLIAIDAFFDTQFETTCQQTIHQLLQHSKQ
                     MTADPDIIHRLKHISKASSQLPPVLEHLNHIMDLVKLGNPQLLKQEINRIPLSSITSS
                     SISALRAEKNLTVIYLTRLLEFSFVENTDVAKHYSLVKYYMALNEEASDLLKVLRIRC
                     AAIIHFSESLTNKSISDKRQMYNSVLHYVDSHLYSKLKVSDIAKRLYVSESHLRSVFK
                     KYSNVSLQHYILSTKIKEAQLLLKRGIPVGEVAKSLYFYDTTHF"
     gene            1499..4999
                     /locus_tag="VGY43_001698"
     CDS             1499..4999
                     /locus_tag="VGY43_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEQ4302852.1"
                     /translation="MWREKINDTKKSYKLSFLLSLTGFILGLLLVFIGLSRVSVGHAE
                     TRNGANKQGAFEIKKVDQNNKPLSGATFSLTPKDGKGASVQTFESGSDGKIDAKDIKP
                     GTYTLKEDKAPDGYDKTSRTWTVTVYENGYTKLVENPYNGEIISRAGSKDVSQSLQLE
                     KSTMSVVSKYGEQEKTSNSADFYRNHAAYFKMSFELKQKDKSETINPGDTFVLQLDQR
                     LNPKGISQDIPKIIYDSANSPLAIGKYHAENHQLIYTFTDYIAGLDKVQLSAELSLFL
                     ENKKVLENTNISNFKSTIGGQEIKYGGTVNVIYGNEKNQKDNYVANGLSNVGGSIESY
                     NTQTGDFTWYVYVNPNRTNIPYATMNLWGFGRLTDKQAFSTDSNSSSAQLLNAEIYEV
                     PSDYHLPSSYGVDVTKLTLRTDITAGLGNGFQMTKRQRIDFKDNLKDGKRFVVKVTGK
                     TDQSGKPLVVQSNLASFNDQFAVKSSNPTNNVYFQNEIALSPSKGSGSGTSEFTKPSI
                     TVANLKRVAQLRFKKMSTDNVPLPEAAFELRSSTSDSQKVEAKSNEQGEVHFKDLTSG
                     TYDLYEKQAPKGYQQVTEKLATVTVDTTKPAEEIVKWKKTHPFVKVEVNKEVTIVNHK
                     ETLTFSGKKIWENDRPDQRPVKIQVQLLQNGQKMSDKVQEVTKDNDWSYHFKDLPKYD
                     DKNQEYKYSVEEVKVPDGYKVSYLGNDIFNTRETEFVFEQNNFNLEFGNAEIKGQSGS
                     KIIDEDTLTSFKGKKIWKNDTAENRPQAIQVQLYADGVAVEGQTKFISGSGNEWSFEF
                     KNLKKYNGTGNDIIYSVKEVTVPTGYDVTYSANDIINTKREVITQQGPNLEIEETLPL
                     ESGASGGTTTVEDSRPVDTLSGLSSEQGQSGDMTIEEDSATHIKFSKRDIDGKELAGA
                     TMELRDSSGKTISTWISDGQVKDFYLMPGKYTFVETAAPDGYEIATAITFTVNEQGQV
                     TVNGKATKGDAHIVMVDAYKPTKGSGQVIDIEEKLPDEQGHSGSTTEIEDSKSSDLII
                     GGQGEVVDTTEDTQRGMTGHSGSTTEIEDSKSSDVIIGGQGQVVETTEDTQTGMHGDS
                     GCKTEVEDTKLVQSFHFDNKEPESNSEIPKKDKPKSNTSLPATGEKQHNKFFWMVTSC
                     SLISSVFVISLKSKKRLSSC"
     gene            complement(5265..5930)
                     /locus_tag="VGY43_001699"
     CDS             complement(5265..5930)
                     /locus_tag="VGY43_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302853.1"
                     /translation="MKRCNKYLFTSLLAASMLFSSYKSVHAHDNIDEKGKVHLYWQGN
                     YYVDNYVDYTKTLVDNDKNIEWTVTFNSAKEQWVYPDFSVFLPKGVKAPTEITYEHHY
                     WDGTVHSEKRRNTQWHYNWEKQKTNFNQEFDKFPGYTGWSPSLDKFYKLKNDGKFSHV
                     LVDTYGRQSHTYFSHKMVWKFKTELEEDYKNKWNKLPFIAGIKQNNPLAASFPSYKGE
                     FGE"
BASE COUNT         2028 a         1005 c         1192 g         1720 t
ORIGIN      
        1 aaaatgagta gtgtcataaa aatataagct tttagccact tctccaacag gaattcctcg
       61 ttttaagagt agttgagctt ctttgatttt tgtacttaga atataatgtt gtaaggaaac
      121 atttgagtat tttttaaaga ctgaacgtaa gtgagattcg gaaacatata ggcgcttagc
      181 gatatcagat acctttaatt tggaatacag gtgactatcg acataatgaa gcacactatt
      241 gtacatttga cgtttatcag aaatactttt attggttaat gattcggaaa aatggatgat
      301 agctgcacag cgaattctca aaactttgag caagtcactc gcttcttcat ttaaggccat
      361 gtagtatttg acaaggctat aatgctttgc tacgtcagta ttttctacaa aactgaattc
      421 cagtaaccta gttaaataga taacagtgag gttcttttcc gcccttagag cagaaataga
      481 agatgaggtg atacttgata aggggatgcg attgatttct tgcttgagca attgtggatt
      541 gcctagcttt accagatcca taatatgatt taggtgctct aaaacaggcg gtagttggct
      601 agatgctttg ctaatatgct taaggcgatg aatgatatca ggatcagcag tcatctgttt
      661 tgaatgctgc aacaattgat gaattgtttg ttggcaagtc gtctcaaatt gtgtgtcaaa
      721 aaaagcgtca atagctatca aaaggttccg cacattatta attggaaaat gtgggacaag
      781 tgccatatag gacaagagct cttctttgct acgatgagaa gaatgtttta aaaaattatt
      841 agctaattgt tcctgatagt ctttattaag tgaataaggg tagaaaggtc caatggcaat
      901 aatgtagtga caaagaggaa aaatcataaa ggactcttca aataaaccct cataaaaaat
      961 aacatcttgt gcagcttgag gaatagctag atgctttaaa aattgatagt aacataataa
     1021 atagtcgtca ttaccatata cttgaataag tgccttatct tgtgacatca ctgaaataga
     1081 taattgagac aagctgtgta atgtttgcac atgttttaaa tcgaatataa ccatttgata
     1141 gattgccccc atccttagtt gtatcatttt ccttagactt gtaaaagctt tagtaaatgt
     1201 taatgatgaa aattcctatt tggtaggcac actaaaaggt cttcctaata gtaatctctc
     1261 tctccatcat ctcctgcctt aattatacta tgaatagcta agcagataaa gataaaggac
     1321 ttgtacgtta agcgcttgaa aaagaaagag ttacagataa tgacataaaa aacgctaaaa
     1381 aaccatcaaa ataaatattc taaccataag atgtagactt gacaactgaa aatggtaaaa
     1441 taactatttg acagttgtcc tgtagtcttt agttttggac ataggctgtc gcttatgaat
     1501 gtggagagag aaaataaatg acacaaaaaa aagctataag ttaagcttcc tgttatcctt
     1561 aacaggattt attttaggtt tattattggt ttttatagga ttgtccagag tatcagtagg
     1621 acatgcggaa acaagaaatg gagcaaacaa acaaggagct tttgaaatca agaaagtcga
     1681 ccaaaacaat aagcccttat cgggagcaac tttttcactg acaccaaagg atgggaaggg
     1741 agcatctgtt cagacctttg aatcaggttc agatggcaag attgatgcta aggatattaa
     1801 accagggact tataccttaa aagaagataa agcaccagat ggttatgata aaaccagtcg
     1861 gacttggaca gtgactgttt atgagaacgg ctataccaag ttggttgaaa atccctataa
     1921 tggggaaatc atcagtagag cagggtcaaa agatgttagc cagtctttac agttagaaaa
     1981 atcaacaatg tctgttgtat ccaagtacgg tgaacaagaa aaaacgtcaa actcagcgga
     2041 tttctaccgc aaccatgccg cctattttaa aatgtctttt gagttgaaac aaaaggataa
     2101 atctgaaaca atcaacccag gcgatacctt tgtgttacag ctggaccaac gtctcaatcc
     2161 taaaggtatc agtcaagata tccctaaaat catttacgac agtgcaaata gtccgcttgc
     2221 gattggaaaa taccatgccg agaaccatca acttatctat actttcacag attatattgc
     2281 aggtttagat aaagtccagt tgtctgcaga attgagctta ttcctagaga ataagaaagt
     2341 gttggaaaac accaacattt caaattttaa gagtactatt ggtggtcagg agatcaaata
     2401 cggtgggaca gttaatgtta tttacggaaa tgaaaaaaat caaaaagaca actatgttgc
     2461 taacggattg agcaatgtgg gtggaagtat tgaaagctac aatacacaaa caggcgactt
     2521 tacttggtat gtttatgtca acccaaatcg taccaatatt ccttatgcga ccatgaattt
     2581 atggggattt ggaaggttaa cagataaaca agctttctca actgattcta atagcagtag
     2641 tgctcagtta ttaaatgcgg aaatttatga agtgccttct gattaccatt taccatcaag
     2701 ttatggggtt gatgttacaa aacttacttt aagaacggat atcacagcag gcctaggaaa
     2761 tggttttcaa atgaccaaac gtcagcggat tgattttaaa gataacctta aagatggaaa
     2821 aaggtttgtt gttaaagtaa cagggaaaac agaccaatct ggtaagccac tagtcgttca
     2881 atccaatttg gcaagtttta atgaccaatt tgctgtaaaa tctagcaatc caactaataa
     2941 tgtctatttc caaaacgaaa ttgccttgtc tccttctaag ggtagtggtt ctgggacaag
     3001 tgaatttact aagccctcta ttacagtagc aaatctaaaa cgagtggctc agcttcgctt
     3061 taagaaaatg tcaactgaca atgtgccatt gccagaagcg gcctttgagc tgcgctcatc
     3121 aactagtgac agtcaaaaag tagaagcaaa atcaaatgaa caaggagagg ttcactttaa
     3181 ggacctgacc tcgggcacct acgacttgta tgaaaaacaa gcacctaaag gctatcagca
     3241 ggtgacagag aaattggcga ctgttactgt tgatactacc aaacctgctg aggaaatagt
     3301 caagtggaaa aagacacatc cgtttgtaaa agtagaagtt aacaaagaag tcacgattgt
     3361 caaccataaa gaaaccctta cgttttcagg gaagaaaatt tgggagaatg acagaccaga
     3421 tcaacgccca gtaaagattc aagtgcaact gttgcaaaat ggtcaaaaaa tgtccgataa
     3481 agttcaagaa gtaacgaagg ataacgattg gtcttatcac ttcaaagact tgcctaagta
     3541 cgatgacaag aatcaggagt ataagtactc agttgaagaa gtaaaagttc cagacggcta
     3601 caaggtgtcg tatttaggaa atgatatatt taacaccaga gaaacagaat ttgtgtttga
     3661 acagaataac tttaaccttg aatttggaaa tgctgaaata aaaggtcaat ctgggtcaaa
     3721 aatcattgat gaagacacgc taacgtcttt caaaggtaag aaaatttgga aaaatgatac
     3781 ggcagaaaat cgtccccaag ccattcaagt gcagctttat gctgatggag tggctgtgga
     3841 aggtcaaacc aaatttattt ctggctcagg taatgagtgg tcgtttgagt ttaaaaactt
     3901 gaagaagtat aatggaacag gtaatgacat catttactct gttaaagaag taactgttcc
     3961 aacaggttat gatgtgactt actcagctaa tgatattatt aataccaaac gtgaggttat
     4021 tacacaacaa ggaccgaacc tagagattga agaaacactt ccgctagaat caggtgcttc
     4081 aggtggtacc actactgtcg aagactcacg cccagttgat accttgtcag gtttatcaag
     4141 tgagcaaggt cagtccggtg atatgacaat tgaagaagat agtgctaccc atattaaatt
     4201 ctcaaaacgt gatattgacg gcaaagagtt agctggtgca actatggagt tgcgtgattc
     4261 atctggtaaa actattagta catggatttc agatggacaa gtgaaagatt tctacctgat
     4321 gccaggaaaa tatacatttg tcgaaaccgc agcaccagac ggttatgaga tagcaactgc
     4381 tattaccttt acagttaatg agcaaggtca ggttactgta aatggcaaag caactaaagg
     4441 tgacgctcat attgtcatgg ttgatgctta caagccaact aagggttcag gtcaggttat
     4501 tgatattgaa gaaaagcttc cagacgagca aggtcattct ggttcaacta ctgaaataga
     4561 agacagtaaa tcttcagacc ttatcattgg cggtcaaggt gaagttgttg acacaacaga
     4621 agacacacaa cgtggtatga caggccattc tggctcaact actgaaatag aagatagcaa
     4681 gtcttcagac gttatcattg gtggtcaggg gcaggttgtc gagacaacag aggataccca
     4741 aactggcatg cacggggatt ctggttgtaa aacggaagtc gaagatacta aactagtaca
     4801 atccttccac tttgataaca aggaaccaga aagtaactct gagattccta aaaaagataa
     4861 gccaaagagt aatactagtt taccagcaac tggtgagaag caacataaca agttcttttg
     4921 gatggttact tcttgctcac ttattagtag tgtttttgta atatcactaa aatccaaaaa
     4981 acgcctatca tcatgttaag ataagctgtt ggtgacaata gcgaaaaagg gtccacttat
     5041 tagtgggcct ctttttctgg aatcgatcgt ctcggttcac tagataagtc attttaagta
     5101 gttcaaaaag gcagagcctt aaaaggtttt ctgccttttt aatcttgttg ggcacttacg
     5161 aaagtatttc ggccacttca agcataataa aaagagtctg agcaatcatg ttgtctcaga
     5221 ctctgactgt aattatgcaa aagatgatgg actggcagct tcatttactc accgaactcc
     5281 cctttataac ttgggaatga tgctgctaat gggttgtttt gtttaatacc tgctataaac
     5341 ggtaatttat tccatttatt tttataatct tcttcaagct cagttttaaa cttccaaacc
     5401 attttatgag aaaaataagt gtgtgattga cggccatagg tgtctactaa aacgtgagaa
     5461 aattttccgt cgttttttag tttgtaaaat ttatctagag aaggactcca accagtataa
     5521 ccagggaatt tatcaaattc ttgattaaaa tttgtttttt gtttttccca attataatgc
     5581 cattgtgtat tcctgcgttt ttcagaatga actgtaccgt cccaataatg atgctcataa
     5641 gttatctccg taggagcttt tacaccctta ggaagaaaaa ctgagaaatc agggtaaacc
     5701 cattgttctt tagctgaatt aaaggttaca gtccattcga tatttttatc gttatcgacc
     5761 aatgttttag tatagtcgac atagttatca acatagtaat ttccctgcca gtaaaggtgc
     5821 actttacctt tctcatcaat gttatcatgg gcatgtactg atttatacga actaaacagc
     5881 atcgaagctg ctagtagtga agtgaagaga tatttattac atcgtttcat atcatgaaaa
     5941 acctt
//
LOCUS       DAUCXI010000073         5313 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.073, whole genome shotgun sequence.
ACCESSION   DAUCXI010000073 DAUCXI010000000
VERSION     DAUCXI010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5313
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.073"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..1911
                     /locus_tag="VGY43_001700"
     CDS             <1..1911
                     /locus_tag="VGY43_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEQ4302854.1"
                     /translation="NQKIVNYIAHFNSYNILKKGSHLSGAYKRKIFSKENTRFIGVKN
                     INSVEGSRKKLLTDFNCEPNFLLDNDSHEIDSLGKNNLWLKGGKISFNMFQEALFDYN
                     VSVSLCEPSFKQKSYIKGLYIENRGENRSFLAGDKLKKDKDFFLTFSPSMNCLIGGRG
                     TGKSTLIDMLQFVLSQDCDKQSKLEFLCNHANAFVLYVLEETEYIIEVSLPDVKQENK
                     DNILQYYGQNRENRFGYSYIFNSDSIKEWTRSLYTKVYKVEGNHFKLVDKTRILEKMF
                     DRRYSVNELVKTADGEKITEFISNLMIKNKKLPRPDYGLRTQTLESFEVKLKELDEYL
                     KQRKQLILEIIEDFNKTQIGKLRICYEQIDRWEEPHLESYLFKNNRSSFENYRISMQD
                     VADVLYLIYRELGMKEFVKVIVRQNIPNKYFMLLKSISEDNFAKQENNWRDKSEINEY
                     NITHLKTSIYSLIENSSLLNEFKRVLKAHVANERLFLEFNINSKETSHQLDILYKEVG
                     VLSLGQKVVAMLDFLLAYSDYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQ
                     IILATHNATIVTNSMTDQVVIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFK
                     HKMSIYETALSE"
     gene            2831..3187
                     /locus_tag="VGY43_001701"
     CDS             2831..3187
                     /locus_tag="VGY43_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302855.1"
                     /translation="MPEQYRDIRKEVNLTANELEMIDIMMKNKGFEHFSSFARNKLLE
                     NELEMTAEKWFTFWHSQKLEQISRDVYEILILSRAEHQVTQEHVSILLTCVQELIQEI
                     GNSIPLSQDFRKKYMR"
     gene            3192..3557
                     /locus_tag="VGY43_001702"
     CDS             3192..3557
                     /locus_tag="VGY43_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEQ4302856.1"
                     /translation="MENRYRTKLKKVFLSDSELSQLKHCIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTTGYQDLIFELKRIGNNINQIARSVNQSQLISSEELQDLKKGIADLISE
                     VEKEFSVQAKKLREFYGHH"
     gene            3544..>5313
                     /locus_tag="VGY43_001703"
     CDS             3544..>5313
                     /locus_tag="VGY43_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEQ4302857.1"
                     /translation="MVITKHFAIHGKSYRRKIIKYILNPDKTKNLALVSDYGMRNFLD
                     FPSYDEMVQMYHENFISNDTLYNFRHARLEEKQRKIHAHHIIQSFSPEDHLTPEQINQ
                     IGYETMKELTGGKFRFIVATHADKNHLHNHIIINSVDSNSDKKLKWDYNVERNLRMIS
                     DRFSKIAGAKIIENRYSHQQFEVYRKTNYKYELKQRLYFLIENSTDFEDLKKNAPLLH
                     MEMDFSHKHTTFFMTDSTMRQVVRGNKLNRKQPYTEEFFKNYFAKRKIEELMEFLLPN
                     VDNLETLIKKAKLFGLNISPKQKHVSFQFSGVEVKETEINKKNLYDVEFFKDYFEKRK
                     KLKAPELKDLVQVYQEEKISKEKELPSEEKFWESYQGFRKNRDAVHEFEVELSFNQIE
                     KVVDDGIYIKIKFGIRQEGLVFVPNMELDMEEDKVKVFIRETSAYYVYHKDDAEKNRY
                     MKGRTLIRQFSSENQTIPFHRKTTVEMIEEKIEEVDALIKLNVENQSYITIKDELVRE
                     LAASELRINALQERVITLNQVAEYLLSSVKNKQEMKLNLSKLNITEAISINVVEENLK
                     ELGNQLALEKDRYENIVFKMNKFI"
BASE COUNT         1931 a          748 c         1052 g         1582 t
ORIGIN      
        1 aatcaaaaaa tagttaatta tattgctcat ttcaatagtt ataacatttt gaaaaaaggt
       61 tctcacttat caggtgcata taaacgaaag attttttcta aagaaaacac acgatttatt
      121 ggtgttaaaa atataaattc tgttgaaggt tctagaaaaa aactattaac agattttaat
      181 tgtgagccca attttttatt agataatgat tctcacgaaa ttgattcact cgggaagaac
      241 aatctgtggt tgaaaggtgg aaaaatttct ttcaatatgt ttcaagaagc attgtttgat
      301 tataatgtat cagttagttt atgtgagcca agctttaaac aaaagtctta tataaaagga
      361 ttatatatag aaaatcgtgg ggaaaataga agttttcttg caggtgataa attaaaaaaa
      421 gataaagact tctttttaac attttcacca tctatgaatt gtttaattgg agggagaggt
      481 acagggaaaa gcacattaat tgatatgtta caatttgtac tttctcaaga ttgtgataag
      541 caaagcaaat tggaatttct atgtaaccat gcaaatgctt ttgtactcta tgttttagaa
      601 gaaactgaat atattattga agttagtttg ccagatgtca aacaagaaaa taaggataat
      661 attttacaat attatgggca aaatcgagag aataggtttg gctattctta catatttaat
      721 tctgactcta ttaaagaatg gacacggtct ctgtacacaa aagtttataa agttgaaggt
      781 aaccatttta aattagttga taaaactaga attttagaga aaatgtttga taggagatat
      841 tctgttaatg agttagttaa aacagctgac ggtgaaaaaa ttacagaatt tatttctaat
      901 ttaatgatta aaaataaaaa attaccgaga ccagactatg ggctaagaac tcagacactc
      961 gaatcgtttg aagtaaaatt aaaggaactt gatgaatatt taaaacagcg gaagcaatta
     1021 atactcgaaa ttattgagga ttttaataaa actcagattg gtaagttaag aatttgttat
     1081 gaacaaattg atagatggga agaaccgcat ttggaaagtt atcttttcaa gaataaccgt
     1141 tcttcgtttg aaaattatag aatcagtatg caagatgtag cagacgtttt atatcttatc
     1201 tatcgggaat taggaatgaa agaatttgtt aaagtcattg taagacaaaa tattcctaat
     1261 aagtatttta tgcttttaaa aagtatctct gaagataatt ttgcaaaaca agaaaataat
     1321 tggagagata aatctgaaat taatgaatac aacattacgc atttaaaaac gagtatctac
     1381 tctttaattg aaaatagtag tttattaaat gagtttaaaa gagttttaaa agcgcatgta
     1441 gcaaatgaaa ggttattttt ggagtttaat attaactcca aagaaacctc acaccaactt
     1501 gatatcctct ataaagaagt tggtgtatta agtttgggac aaaaagttgt agccatgctt
     1561 gattttttat tagcgtatag tgattattct aaagacttca gaccattgat tattgatcag
     1621 cctgaagata atctagataa tcgttatatt tacaggcatt tagttcagca gtttagagat
     1681 gtgaaagctc aacgacaaat tattttagca acacataatg ctacaattgt aacaaattct
     1741 atgacagatc aagttgttat tatggagtca gatggagtta acggatggat tgaatcacag
     1801 ggatatgtta gtgaaaaata tataaaaaat catatcatca atcaattaga gggagggaaa
     1861 gattccttca agcataaaat gtctatatat gagacggctt tatcagagta gagccagaaa
     1921 aagtaggtta gaaatttagc ctactttttc tttgttcgac aggcatagtg tacatctgag
     1981 gtccaagtct tcttttgata tctgctgcag atgaaaccaa tagcgactcc taagcctgaa
     2041 tatcttgagg taggggggag aggaaggaat tagcgaaatc aaggctctac aaacagaatc
     2101 gtgacttgaa gccatatagc ggatgaggaa ttctaaaatc caaataggtg tcgtaaccta
     2161 tatacgtaaa ttacgagagt aaactaggaa agatgtacgg cttattccgt gagcgtttag
     2221 gacgtagtac aacgaatcat gggagtcagc tgaacccata gtattgaaga aatttctgta
     2281 atggaaatgg agcgaagggt gaacaactaa atggatatct ctctaattaa atttgtcaat
     2341 cctaattcct ggcctgaaaa gacagtgaac tgaaaacgta aatgatggaa gctgatcaca
     2401 aatataggac ggcactgata gaacgaattg taaaatgaaa agatgagtga gtataatgct
     2461 ctcgttaaaa cttagttggc ccgctgtgtg ccgaacggta cgcacagtgg tgttagatgg
     2521 gctagagatt agtccctaat cgatctgtga taacttcttc aaataatcct tgttatccta
     2581 atatcatcct aagaaaatcg atactcaaat ttaaactggg ggtttggggg cgaagccacc
     2641 aagttatctt atcgttggct atcaaaacta gaaggttttg gtcggctggc gatatgattt
     2701 ttgggatatt gtggacacaa tatctgagct cgcaaagcct tacaagatgc tatattttgt
     2761 ttttataagt ttcccgtggt tgacacgggg tcgggaatta tccgacaata gatgaaagtg
     2821 aggaagtagt gtgccagaac aatacagaga cattcgcaaa gaggttaatt tgactgcaaa
     2881 tgaattagaa atgattgaca taatgatgaa aaataaagga tttgaacact tttcttcatt
     2941 tgccagaaac aagttactgg agaacgagtt agaaatgact gctgaaaagt ggttcacctt
     3001 ctggcattct caaaagctgg aacaaatcag tcgtgatgtt tatgagattt taatcttatc
     3061 aagggcagaa catcaagtca cccaagaaca tgtatccatt ctcttaacct gtgttcagga
     3121 attgattcaa gaaataggga actccattcc tcttagtcaa gacttccgta aaaaatacat
     3181 gaggtaggca catggaaaat cgttaccgaa ctaagctaaa gaaagttttc ctatctgata
     3241 gcgaattgag tcagttgaaa cattgcatcg atcaaagcgg ttgtaaatct ttttcagaat
     3301 atgctcgacg aaccctactt gaccctggta tgaatttcat caccattgat acaactggtt
     3361 atcaagattt gatatttgag ttgaagagga ttggtaataa catcaaccag attgcccgaa
     3421 gtgttaatca atctcagttg atttcaagtg aagaattgca agacttgaaa aagggaatcg
     3481 ctgacttgat aagtgaggta gagaaagagt ttagtgttca agcaaaaaag ttgagggagt
     3541 tttatggtca tcactaagca ttttgccatt cacggaaaga gttatcgcag aaaaattatc
     3601 aagtatattc ttaatcctga taagactaag aatcttgcat tggtatcgga ctatggcatg
     3661 agaaattttc tggattttcc tagctatgat gagatggtgc agatgtatca tgaaaatttt
     3721 atcagcaatg atacgcttta taattttcgg catgctaggt tagaggaaaa gcaacgaaaa
     3781 attcatgccc atcatatcat tcagtctttt tctccagagg atcatctcac tcctgaacaa
     3841 atcaatcaga ttggctatga gacaatgaag gagttaaccg gtggaaaatt tcgttttatc
     3901 gttgcgactc acgctgataa aaatcacctc cataatcaca tcattatcaa ctcggttgat
     3961 agtaattcgg acaaaaaact caagtgggat tataatgtgg aacgaaatct tcgaatgatt
     4021 tcagatagat tttctaaaat tgcaggggcg aaaattatag agaatcgcta ttcccaccag
     4081 cagtttgaag tttatcgtaa gaccaattac aagtacgaac tcaagcagcg actctatttt
     4141 ttgattgaaa attctaccga ttttgaggat ttaaaaaaga acgctccatt actacatatg
     4201 gagatggatt tcagtcacaa gcataccacc ttttttatga cggactcaac tatgagacaa
     4261 gtggtgcgtg gtaataaact caatcgcaag caaccttaca cagaagagtt tttcaagaat
     4321 tactttgcca aaagaaaaat agaagagctt atggaatttc ttctacccaa tgttgataac
     4381 ttagaaactc tgataaaaaa agcaaaacta tttggattaa atatcagtcc taagcaaaag
     4441 catgtttctt ttcaattttc aggagtagag gtgaaagaga ccgaaataaa taagaaaaat
     4501 ctttacgatg tagaattttt caaagattat tttgaaaaga gaaaaaaatt gaaagctcca
     4561 gaacttaagg atttagttca agtttatcaa gaagagaaaa tctccaaaga aaaagaactc
     4621 ccaagcgagg agaaattttg ggagtcctat caagggttca ggaaaaacag ggacgctgtt
     4681 catgaatttg aggtagagtt gtcatttaat caaatcgaaa aagtagtgga tgatggaatt
     4741 tacatcaaga tcaagtttgg tattcgtcag gaggggcttg tctttgtacc taacatggag
     4801 ctagatatgg aagaggataa ggtaaaggtt tttattagag aaactagcgc ctactatgtc
     4861 tatcacaaag atgacgccga gaaaaaccgc tatatgaaag gtagaacgtt gattcgccaa
     4921 ttcagctctg aaaatcaaac aattccattc cacagaaaaa cgactgtgga gatgattgaa
     4981 gaaaagattg aagaagtgga tgctttgatt aagttgaatg tggaaaatca atcttatatc
     5041 acgattaaag acgagctagt gcgtgaacta gcagcgtctg agttgagaat caatgctttg
     5101 caagaacgag tgataacctt aaatcaagta gcagaatatt tactgtcttc agttaaaaac
     5161 aagcaagaaa tgaagttgaa tctttcaaaa ttgaatataa ctgaggcaat tagtattaat
     5221 gttgtggaag agaatctgaa ggagttggga aatcaattgg cattagaaaa agatagatat
     5281 gagaacatcg tatttaaaat gaataagttt atc
//
LOCUS       DAUCXI010000074         5079 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.074, whole genome shotgun sequence.
ACCESSION   DAUCXI010000074 DAUCXI010000000
VERSION     DAUCXI010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5079
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.074"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(48..290)
                     /locus_tag="VGY43_001704"
     CDS             complement(48..290)
                     /locus_tag="VGY43_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017228.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEQ4302858.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHIAIPDEDVEDMVFMGDVLDYLVQRLT"
     gene            complement(283..1290)
                     /gene="plsX"
                     /locus_tag="VGY43_001705"
     CDS             complement(283..1290)
                     /gene="plsX"
                     /locus_tag="VGY43_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEQ4302859.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDSLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            complement(1393..2148)
                     /gene="recO"
                     /locus_tag="VGY43_001706"
     CDS             complement(1393..2148)
                     /gene="recO"
                     /locus_tag="VGY43_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEQ4302860.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAVI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            complement(2334..3296)
                     /locus_tag="VGY43_001707"
     CDS             complement(2334..3296)
                     /locus_tag="VGY43_001707"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEQ4302861.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMGLQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEMGN"
     gene            complement(3549..4745)
                     /locus_tag="VGY43_001708"
     CDS             complement(3549..4745)
                     /locus_tag="VGY43_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEQ4302862.1"
                     /translation="MKKRILSAVLVSGVTLGAATVVSADNFDAKISDANSRISALTAE
                     QQSAQNQVNALQAQVSSLQAEQDKLTAKNSELEELSKGFEQEIQSLTNQIIARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVITRLVAINKAVSANAKMLEQQKADKASLEE
                     KQAANQEAINTIAANMSAIKENQNALRTQQADLEVAKVNLAIQLASAEDEKASLLNQQ
                     AAAQQAAAEALAAQQAAQAKAREEAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPASPSARPQVSYSSVNNYPVGQCTWGAKSLAPWAGNNWGNGGQWAASAQAAGYS
                     VGSTPMVGAIAVWNDGGYGHVAVVVEVQSSSNIRVMESNYSGKQYIADHRGWFNPTGV
                     TFIYPH"
BASE COUNT         1626 a         1018 c          765 g         1670 t
ORIGIN      
        1 tttttaaaga ataataaaaa gagcttacgc tctttttatt attctaacta agtcaaacgc
       61 tgaactaaat aatctaaaac gtctcccata aataccatat cctcaacatc ttcatcagga
      121 atagcaatat gaaattcatc ttcaacatta ataataaatt caactagttc aatagagtca
      181 accgctaaat cattttttaa atgtgtttgt tctgtaatag ctacactcaa atagcttctt
      241 tgcttctgaa ttaagttaat cagcctttca aaaatctcct gtctagtcat ttacttgagt
      301 ctccttagca aattcttcta ctaattgtcc gaccacgtta gtgtctagca tcgtacgtac
      361 ttgttttatc gttgaaaaaa tagcttttac atcactagaa ccatgagact ttacaacagg
      421 tgcctttaaa ccaaataaaa ctgcacctcc agcactagag tagtcaagag tcttcttcat
      481 ctcgtaaaga ctacttttaa gtagactagc tccaatttta gtcttaatac cgccgctatt
      541 aattatctgt ttcagttgcc ccataatgct aatagctgtt ccttctattg atttcaacac
      601 tgcgtttccc gtgaaaccat ctgatacaat aacatctgca acacctgaca taagttctcg
      661 cgcctcgaca ttaccaacaa aagatattgt attatctgct gttaaaagtt cataagtagc
      721 cttacgaagg gaatctcctt ttgtttcttc tgtaccattg tttaatagac caacacgtgg
      781 attagcaatc ccacgtacat tcttagcata gaaagagcct aaaatagcat attgatgtaa
      841 atgttttgcc gtattttcag cattagctcc aagatccaac atatcaaatc ctaatccggt
      901 tactgtggga atagttgata ataatcctgg acgatcaact cccttgatac gccccacaac
      961 aaacaaacct acagctaaaa gagcacctgt attccctgct gaaataatgg catctgcttt
     1021 tccttctttc actgccttag ctgctaaaac cattgaagcc ttctttttac ggcgaacagc
     1081 ttttgcaggt tcatcatctg acataatttt ttcatctgta tgaataatag caacacgatc
     1141 tgattgaata agataggagt taatctttgt ctgatcaccg taaagttgaa tttcgatatc
     1201 tgaaaatgct tctattgctt gattaacacc ctcaacaata gctttaggag cgttatctcc
     1261 acccatagca tctattgcaa ttctcttcat ttccactcct ttaattatat cttgtgttct
     1321 tacacaatct attaatagta tttttattat agcatattct gaaaccaatt cccataaacg
     1381 aaagaggccc tatcatttca taatatctcc ccacttaact aaattatcaa tgaatgtttt
     1441 actttttaat ttgattccta catagtcgtg atacaactca tcaatgaact gacgaagctt
     1501 ctttttgatg tctttattca atgaaatagt tctcaaatca tcaaatgtga ttttttgaaa
     1561 tcgactcaac aagtagataa catttggatc taaatgatta cgtcggttgt ctttgtaata
     1621 atgttcagaa caaagtacag ctgaaaaacg atgggaaaaa tcaagcggta aatcagtgcg
     1681 atgacaaatg gcacactcat gaaagtttag actaatacca aaacgatcta atatctgaat
     1741 ttcaaaaata tttgtcaaaa tttcataatc taggccctct tccatcaaat caagtgtttt
     1801 tttcaaaaac gtaaacaaat gcgaatctga ttcattatct gcaatcacag catcagctaa
     1861 tgctaagaca taactagcat aggctaatcg aaaaatatca ttattaatat accgataagt
     1921 gttaacgtta ctatagtcaa caacataaga caagcctgta tcatttaact tgaaaataaa
     1981 atcagcaatc gttagtggtt gaatgattga ggacattttg gaacgactaa tatgtttcac
     2041 gaaaaacatc tgcttacctg ctacttcagt aaatattttg actaatttat catcttctcg
     2101 ataattccta ttaaaaagaa caatgcctag tgattctgtt agttgcatat tacctcgtcg
     2161 tatttttctc ttacctttta tcttagttta caataaactg ttgttatctt tcttattata
     2221 cccaaaatcc tttagaattg catagttcat cccacaataa ttaataccac attaccctta
     2281 cattttattc aagtcaaaaa gcccgagatc tattatctca ggcttcgtta agcttaattg
     2341 cccatctcaa ataaaggtga caacggacgt ttttcatgaa tacgaataat cgcttctgca
     2401 accaaatcag caattgaaat ttgttcaatt ttatcaataa gacgttcttt tggcagataa
     2461 atagtatcaa gaacaattag tttttcgata gccgaacgtt gaatattatc aagtgctggt
     2521 ccagaaagaa cgggatgcgt gcatgacgca tacacagctg ttgcccccgc ttcagcaagc
     2581 gcatctgctg catggcaaat agtccctgcg gtatcaatca tatcgtcaat caagatacat
     2641 ttcttgcccg aaacatttcc gataatattc atcacttcac tggtgttcat cttatccaca
     2701 ctacgacgct tatcgataat tgcaattggt gtttggagga attgtgctaa tttacgcgca
     2761 cgagtcacac caccatggtc aggactaaca acgacaacat cttcacccac taaaccatga
     2821 cgatcaaaat agtctgcaat taaaggtgca cccatcaagt gatcaactgg aatatcaaag
     2881 aacccttgaa tttgagcagc atgtaaatca accgttaata agcgatctac accagcaact
     2941 tctaacatat tagcaactaa ttttgaagta ataggttcac gagaacgcgc tttacggtct
     3001 tggcgtgcat agccgtagta aggcatcaca actgaaattt tttcagcact agcacgcttt
     3061 aaagcatcga ccataatcaa aatttccatt aaattgtcat tgacaggtga gctagttgat
     3121 tgcaaaataa agacatgatg accacgaatt gattcttcaa tatttacttg gatttcacca
     3181 tctgaaaact ggcgaaccgt agactttcca agttgaagac ccattgcaga cgcaactttt
     3241 tctgctaatt ccttgtttga cgataaagca aacaatttta aatcagaata agacattttt
     3301 tcctccaaag ttttaatcct ataccatttt aacgcttttc aagtgaatta tcaaatgaaa
     3361 ttgaaaaacc gttaaagaat gtattaaata taccttttat cgactttata tacttctctt
     3421 atattataca taagcgattg gccaaacaac tctcttataa attaaccata tcgtcaatac
     3481 tctcagaact attccacaat aggagtaatc aaaaaggtta gaacaactgt tctaacctaa
     3541 ataatatgtt agtgtggata aataaatgta acacctgttg gattaaacca accacggtgg
     3601 tcagcaatat actgtttacc actgtagttt gattccatca ctcgaatatt tgatgaactt
     3661 tgaacttcaa caactactgc gacgtgacca taaccgccat cattccaaac cgcaatagct
     3721 cctaccatag gtgtagatcc tacagagtag cccgctgctt gagcgcttgc agcccattgt
     3781 ccaccgttac cccaattgtt tcctgcccat ggagctaatg atttcgcacc ccatgtacat
     3841 tgtcctactg ggtaattatt aacagaacta tatgaaactt gtggtcttgc agaaggagat
     3901 gccggagccg tgagtgcagc tggttcaata gcattactac tttgcgctgc cggagtagct
     3961 tgtggtgctg gagtaatagc agattttgct gcttcaacag atgctgcttg ttgtgcagct
     4021 tcctctcgag ctttagcttg tgctgcttgt tgtgctgcta aagcttctgc tgctgcttgt
     4081 tgcgctgccg cctgttgatt aagtaaactt gctttttcat cttcagcaga agccaattga
     4141 atagctaaat tgactttagc aacttccaaa tctgcttgtt gtgtacgcaa agcattttga
     4201 ttttctttaa tggctgacat atttgcagca attgtattaa tagcttcttg gttagccgct
     4261 tgtttttctt caagtgaagc tttatcagct ttttgttgct ctagcatctt agcattagca
     4321 gagactgctt tgttaatagc aactaaacga gtaatcacgt cagaaattga tttagaattc
     4381 aaaagtgcat taatgtaacc agaagtttca ttgtttttat aagcactacg agcttgattt
     4441 tttaattttt cattacgagc aataatttgg tttgtaagag attgaatttc ttgttcgaat
     4501 ccttttgaaa gttcttcaag ttctgaattt tttgctgtta atttatcttg ttcagcttgt
     4561 aatgaactaa cttgtgcctg taatgcatta acttgattct gagcagattg ctgttctgca
     4621 gttaaggctg agattcttga gttagcatca gagattttgg catcaaaatt atccgcgcta
     4681 actacagtag ctgctccaag ggttacacca cttacaagaa cggctgatag aattcttttt
     4741 ttcataataa aaaaactact ccttttcgat aagacatctt atattttacc aaaaaaaaaa
     4801 gtatttaata ttacgcaatt gttacagtta tatgtaataa acaataaaaa tattttaggg
     4861 attatcttat aaaagtaaag cagccaaaaa gatatatctt tcatttaaaa tagaatacag
     4921 taaaatcaat ttaaatacat aaaattgtat aaaattacac aaaaagtttg aaaattatat
     4981 cttaataatg ctataagtaa tacaaaattg tttatcttca ctcagacacc ttctccttct
     5041 tagaatgaat ttttagttac ttatccacag gttaataac
//
LOCUS       DAUCXI010000075         4946 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.075, whole genome shotgun sequence.
ACCESSION   DAUCXI010000075 DAUCXI010000000
VERSION     DAUCXI010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4946
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.075"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..1441
                     /locus_tag="VGY43_001709"
     rRNA            <1..1441
                     /locus_tag="VGY43_001709"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1493..1565
                     /locus_tag="VGY43_001710"
     tRNA            1493..1565
                     /locus_tag="VGY43_001710"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1526..1528,aa:Ala,seq:tgc)
     gene            1864..4766
                     /locus_tag="VGY43_001711"
     rRNA            1864..4766
                     /locus_tag="VGY43_001711"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4852..>4946
                     /gene="rrf"
                     /locus_tag="VGY43_001712"
     rRNA            4852..>4946
                     /gene="rrf"
                     /locus_tag="VGY43_001712"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1393 a         1019 c         1420 g         1114 t
ORIGIN      
        1 gggtgagtaa cgcgtaggta acctacctca tagcggggga taactattgg aaacgatagc
       61 taataccgca taagagagac taacgcatgt tagtaattta aaaggggcaa ttgctccact
      121 atgagatgga cctgcgttgt attagctagt tggtgaggta aaggctcacc aaggcgacga
      181 tacatagccg acctgagagg gtgatcggcc acactgggac tgagacacgg cccagactcc
      241 tacgggaggc agcagtaggg aatcttcggc aatgggggca accctgaccg agcaacgccg
      301 cgtgagtgaa gaaggttttc ggatcgtaaa gctctgttgt tagagaagaa tgatggtggg
      361 agtggaaaat ccaccaagtg acggtaacta accagaaagg gacggctaac tacgtgccag
      421 cagccgcggt aatacgtagg tcccgagcgt tgtccggatt tattgggcgt aaagcgagcg
      481 caggcggttt tttaagtctg aagttaaagg cattggctca accaatgtac gctttggaaa
      541 ctggagaact tgagtgcaga aggggagagt ggaattccat gtgtagcggt gaaatgcgta
      601 gatatatgga ggaacaccgg tggcgaaagc ggctctctgg tctgtaactg acgctgaggc
      661 tcgaaagcgt ggggagcaaa caggattaga taccctggta gtccacgccg taaacgatga
      721 gtgctaggtg ttaggccctt tccggggctt agtgccggag ctaacgcatt aagcactccg
      781 cctggggagt acgaccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagcg
      841 gtggagcatg tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatcccg
      901 atgcccgctc tagagataga gttttacttc ggtacatcgg tgacaggtgg tgcatggttg
      961 tcgtcagctc gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa cccctattgt
     1021 tagttgccat cattaagttg ggcactctag cgagactgcc ggtaataaac cggaggaagg
     1081 tggggatgac gtcaaatcat catgcccctt atgacctggg ctacacacgt gctacaatgg
     1141 ttggtacaac gagtcgcaag ccggtgacgg caagctaatc tcttaaagcc aatctcagtt
     1201 cggattgtag gctgcaactc gcctacatga agtcggaatc gctagtaatc gcggatcagc
     1261 acgccgcggt gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgagagttt
     1321 gtaacacccg aagtcggtga ggtaacctat taggagccag ccgcctaagg tgggatagat
     1381 gattggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga tcacctcctt
     1441 tctaaggaaa tggaacacgt ttatcgtctt atttagtttt gagaggtctt gtggggcctt
     1501 agctcagctg ggagagcgcc tgctttgcac gcaggaggtc agcggttcga tcccgctagg
     1561 ctccatcagg atacaatcct actaaactta atacaagtga agttgaacac gcaactcact
     1621 tcctaggaaa atagacaatc ttcccttgtg tgcaaggccc acatggtcag attcctaatt
     1681 ttctacagaa gtttcgctaa agcgagcgtt gcttagtatc ctatataata gtccattgaa
     1741 aattgaatat ctatatcaaa ttccacgatc tagaaataga ttgtagaaaa gtaacaagaa
     1801 aataaaccga aaacgctgtg actatttaat aagttttcta gtttaaaaaa actaggttaa
     1861 taaggttaag ttaataaggg cgcacggtgg atgccttggc actagaagcc gaagaaggac
     1921 gtgacaaacg acgaaatgct ttggggagct gtaagtaagc gctgatccag agatgtccga
     1981 atgggggaac ccactaacta atggttagta tccataactg ttaaggttat gagaaggaag
     2041 acgcagtgaa ctgaaacatc taagtagctg caggaagaga aagcaaacgc gattgcctta
     2101 gtagcggcga gcgaaacggc aagagggcaa accgaagtgt ttacacttcg gggttgtagg
     2161 actgcgacgt gggactttaa aaggatagaa gaattacctg ggaaggtaag ccaaagagag
     2221 taaaagcctc gtatttaaaa ttcttttgag ccctagcagt atcctgagta cggcgagaca
     2281 cgtgaaatct cgttggaatc tgggaggacc atctcccaac cctaaatact ctctagtgac
     2341 cgatagtgaa ccagtaccgt gagggaaagg tgaaaagcac cccgggaggg gagtgaaata
     2401 gaacctgaaa ccgtgtgcct acaacaagtt cgagcccgtt aatgggtgag agcgtgcctt
     2461 ttgtagaatg aaccggcgag ttacgatatg atgcgaggtt aagttgaaga gacggagccg
     2521 tagggaaacc gagtcttaat agggcgattt agtatcatgt tgtagacccg aaaccatgtg
     2581 acctacccat gagcaggttg aaggtgaggt aaaactcact ggaggaccga accagggcac
     2641 gttgaaaagt gcttggatga cttgtgggta gcggagaaat tccaaacgaa cttggagata
     2701 gctggttctc tccgaaatag ctttagggct agcgtcgatg ttaagtctct tggaggtaga
     2761 gcactgtttg ggtgaggggt ccatctcgga ttaccaatct cagataaact ccgaatgcca
     2821 acgagatatc atcggcagtc agactgcgag tgctaagatc cgtagtcgaa agggaaacag
     2881 cccagaccac cagctaaggt cccaaaataa ctgttaagtg gaaaaggatg tggggttgca
     2941 cagacaacta ggatgttagc ttagaagcag ctattcattc aaagagtgcg taatagctca
     3001 ctagtcgagt gaccctgcgc cgaaaatgta ccggggctaa aacagtttac cgaagctgtg
     3061 gatgacacaa aagtgtcatg gtaggagagc gttctatgtg tgaagaaggt gtaccgtgag
     3121 gagcgctgga acgcatagaa gtgagaatgc cggtatgagt agcgaaagac aggtgagaat
     3181 cctgtccacc gtaagactaa ggtttccagg ggaaggctcg tccgccctgg gttagtcggg
     3241 acctaaggag agaccgaaag gtgtatccga tggccaacag gttgatattc ctgtactaga
     3301 gtatatagtg atggagggac gcagtaggct aactaaaccg gacgattgga agagtccggc
     3361 taagcagtga ggtgtaagat gagtcaaatg cttatcttta taacattgag ctgtgatggg
     3421 gagcgaattt tagtagcgaa gttagtgatg tcacactgcc aagaaaagct tctagcgttt
     3481 aatgatactc tacccgtacc gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg
     3541 atcgagagaa ctctcgttaa ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg
     3601 tgctgactta ggtcagccgc agtgaatagg cccaagcaac tgtttatcaa aaacacagct
     3661 ctctgctaaa tcgtaagatg atgtataggg ggtgacgcct gcccggtgct ggaaggttaa
     3721 gaggagggtt tagcgcaagc gaagatctga attgaagccc cagtaaacgg cggccgtaac
     3781 tataacggtc ctaaggtagc gaaattcctt gtcgggtaag ttccgacccg cacgaaaggc
     3841 gtaatgattt gggcactgtc tcaacgagag actcggtgaa attttagtac ctgtgaagat
     3901 gcaggttacc cgcgacagga cggaaagacc ccatggagct ttactgcagt ttgatattga
     3961 gtatctgtac cacatgtaca ggataggtag gagccattga ctttgggacg ccagtttcga
     4021 atgaggcgtt gttgggatac tacccttgtg ttatggctac tctaacccag ataggttatc
     4081 cctatcggag acagtgtctg acgggcagtt tgactggggc ggtcgcctcc taaagagtaa
     4141 cggaggcgcc caaaggttcc ctcagattgg ttggaaatca atcgcagagt gtaaaggtat
     4201 aagggagctt gactgcgaga gctacaactc gagcagggac gaaagtcggg cttagtgatc
     4261 cggtggtacc gaatggaagg gccatcgctc aacggataaa agctaccctg gggataacag
     4321 gcttatctcc cccaagagtt cacatcgacg gggaggtttg gcacctcgat gtcggctcgt
     4381 cgcatcctgg ggctgtagtc ggtcccaagg gttgggctgt tcgcccatta aagcggcacg
     4441 cgagctgggt tcagaacgtc gtgagacagt tcggtcccta tccgtcgcgg gcgtaggaaa
     4501 tttgagagga tctgctccta gtacgagagg accagagtgg acttaccgct ggtgtaccag
     4561 ttgttttgcc aaaggcatcg ctgggtagct atgtagggaa gggataagcg ctgaaagcat
     4621 ctaagtgcga agcccccctc aagatgagat ttcccatgat tttatatcag taagagccct
     4681 gagagatgat caggtagata ggttaggagt gtaagtgtag cgatacatgt agcggactaa
     4741 tactaatagc tcgaggactt atccaaaaag aaatattgac aacgttacgg attcttgtta
     4801 gactatagat attcaatttt gagtgggtta tgaaaatagc acatttacaa gttaagtgac
     4861 gatagcctag gagatacacc tgtacccatg ccgaacacag cagttaagcc ctagaacgcc
     4921 tgatgtagtt gggggttgcc ccctgt
//
LOCUS       DAUCXI010000076         4518 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.076, whole genome shotgun sequence.
ACCESSION   DAUCXI010000076 DAUCXI010000000
VERSION     DAUCXI010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4518
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.076"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            150..881
                     /gene="aphA"
                     /locus_tag="VGY43_001713"
     CDS             150..881
                     /gene="aphA"
                     /locus_tag="VGY43_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HEQ4302863.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            1059..2591
                     /locus_tag="VGY43_001714"
     CDS             1059..2591
                     /locus_tag="VGY43_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEQ4302864.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVMVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPILA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGSWLHLPAYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            2754..3368
                     /locus_tag="VGY43_001715"
     CDS             2754..3368
                     /locus_tag="VGY43_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEQ4302865.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     IEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIQSYI"
     gene            3527..>4518
                     /locus_tag="VGY43_001716"
     CDS             3527..>4518
                     /locus_tag="VGY43_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEQ4302866.1"
                     /translation="MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYK
                     TSLPFFYGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITW
                     IISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYS
                     QQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTG
                     KYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGVLVAFTA
                     LIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIG"
BASE COUNT         1381 a          671 c          869 g         1597 t
ORIGIN      
        1 tttttaaatc gattatgata attttttaga tcatctttgt tgaataactt catccttatt
       61 cagaacttaa agggcactat tataagaatt tgaaaccgct ttacttaaat cgtgtatttt
      121 tgtacaataa tgattaagga ggtttttaga tgaaaaaaga atttaccagt atcctgttta
      181 cagttagttt ttgtggaatc atagcattgc ctgtcgaagc tagtggccct aaagttcctt
      241 atacacaaga aggtataacg gccatttcaa atcaggcaac agtaaaattg atttctattg
      301 ctgatatcgc gagcagttta gaaggacaaa aacctataac ggttagtttt gatatcgatg
      361 atactttgtt atttactagc caatattttc aatacggcaa agaatatata actccaggct
      421 catttgattt tttgcataag caaaaatttt gggacttggt cgctaaacgg ggagatcagg
      481 attctattcc aaaagagtat gcaaagcaac taatcgcaat gcatcaaaaa cgaggagata
      541 aaattgtctt tattactggc cgaactcgag gatcgatgta taaaaaaggt gagattgata
      601 aaacagctaa gtcactggct aaagatttta agttagacaa gccaatagct atcaattata
      661 caggagataa agctgtgaag ccgtatcagt atgataaaac atattatata aagaaaaacg
      721 gctcacaaat tcattacgga gatagtgatg aagatataaa tgctgccaaa gaggcaggtg
      781 caagacctat tcgcatttta agagctccta attcaactaa tcttcctttg ccaaaagctg
      841 gaggatacgg agaagaggtt ttagaaaatt cggcttatta gtcaaatatt tgtgtaagaa
      901 aggaagtaac agtaatttct ttcatcaccc cactgagtaa ccaatagccc agtgggtttt
      961 ttgggttaca gaaatcagtt ctaaaaaaga atcactggta acttaaggtt gtctttgata
     1021 caatggtaac agtgtattta aaagaaagag aggataacat ggaaaaccat aaaaatgaat
     1081 tcaccttttc caacaaatca attattgcct atgtttggcg tggtgttatg gttggtatta
     1141 ttgctggtgt tattgttagt ttattccggt tgttaattga agtgacagct gactgggtga
     1201 ttgaatggta ccgatacgct catatcaatt cgctgttgct acttcctata ctaagtgtca
     1261 gtttattagc tgttcttttt gtaggttttt tagtaaagtc tgattctgat ataaaaggat
     1321 cagggatccc ccatgtcgaa ggagaactaa agggactaat gtccccagat tggtggagtg
     1381 tcctttggaa aaaattttta ggaggaatca tggctatttc tatgggattt atgctcggtc
     1441 gtgagggtcc ttcgattcag ttaggtgcta tgtcagccaa aggattagct aagtttttaa
     1501 aatcgagtcg tttggaaaag cgagtgctaa ttgccagcgg agcagcagca gggctatcag
     1561 cagcttttaa tgctccaata gcaggcctct tgtttgttgt tgaagaaatt taccatcatt
     1621 tttcgcgttt aatttggatt acagcgctag tggctagttt agtggctaat tttatttctc
     1681 tgaatatttt tggattgaaa ccaatcttag caatgtcaga ggcgatgcct tttttaggac
     1741 tcaatcaata ttggttgttg cttttacttg gattatttct aggctgctta ggctatttat
     1801 atgagatagt tatccttaat tttaataaac tttatgttat tttagggagt tggttacatc
     1861 tgccagctta tttttacggt attattatgg tttttctaat tttaccgatt ggctattatt
     1921 taccacagtt acttggagga gggcatggtt taatactttc tttatccaat caacaattgc
     1981 ctttgatgac tatcttcttt tattttatta ttcgatttat tgttagtatg tttagttatg
     2041 gaagtggctt acctggaggt atttttttac ctattttaac tttaggtgct ttggcaggcc
     2101 tattatttgg gcaaatagct tctcaattag gtttattgaa ccaatctttt ctttctcttt
     2161 ttttgatatt agggatggca gggtattttg cggcaatttc aaaagcacca ctgacaggca
     2221 tgattttggt aactgaaatg gtaggtgatt tgaaaccctt aatggccata gctgtagtta
     2281 cttttgtctc ctatttagtg atggatttgt taaatggaca gccaatttac gaagctatgc
     2341 tagataagat ggcaatgaag catccaacta atcttgttga accaacatta attgaattga
     2401 ctgttggtga taagattgca gggaaatatg ttaaagagtt aaagcttcca gaaaatgtct
     2461 taattacaac ccaaattcac catcaaaaat ctcaagttgt gtcaggtaac acgcgccttt
     2521 tgtcaggagc aactatcttt ttggtcgtta atgaagctga tacaggtttt gtccgtgagg
     2581 tattgatgta ggtattaatt tatcacaatt cggaaagttc gagcttgtct tttagactaa
     2641 gtcttcgaac gttttactgc tagagtttca tctgaaccaa agtgaaacgc ttttgatgaa
     2701 gtcaagtagg ctttttgtta tactaacaat aaagataagc taaggaggct gagatgttag
     2761 aaattgtttc agaagagcta cgtcactatc aagaacaaaa attgattgag taccgtaaca
     2821 aaaatcagtt agccccaaaa ggaggcattg tatttgcagg tgattctctc attgaatttt
     2881 ttcctttaaa aaaagctttt ggttcatgtt tgcctattat taatcgaggt attgctggga
     2941 tagatagtca gtggttattg cgccattttt ctgtccaaat tactgattta gagcctaaac
     3001 atattttttt attaattggt tgtaatgata tcgggcttgg atatgataaa tgtcatattg
     3061 tcaagactat tgtagagctt attagccaga ttcgtagtca ttgtgtctac agtcagattt
     3121 atctcttatc tttattacca gtttccaaca atccccgata tcagaaaact gtcaaaataa
     3181 gaacaaatgc tatgattgat gctattaata aagatttagc aatgattcca actatagaat
     3241 ttattaatct taatacttgt cttaaagacg aaaaaggtgg tttatcagat gagaatactc
     3301 tagatggttt acatcttaat tttccagctt atgctaaact agctgaaatt attcaatctt
     3361 atatctagcc aataaatgta ctaatagcga tgaggcaaga agtcagatag cagatggttc
     3421 atcaatcaat taagaaaaaa gttatcaaga taccattaaa aatagttgct caaagttctt
     3481 tcaaatcaaa agattatgat atcgctatgt tgagttttag tgtataatga taattaaagg
     3541 agttaccatg aaatttgaaa aaaaacaagt cttctattta gtccttacgt ttatcttatg
     3601 ctatgggatc ctagcaaact ggcgaaatgg aacggctatc gtcacgacta tttacaaaac
     3661 aagccttcct tttttttatg gagcagcagg tgcctatatt gttaatattg taatgagcgc
     3721 ttacgaaaag gtatatgttt atatctttaa agactggtca catgtcttaa aagtaaaacg
     3781 gggtatttgt ttactgttag cgtatttgac attttttatt ttaattactt ggattatttc
     3841 cattgtcatt ccagacttaa ttacaagtat tagtactcta acaaaatttg atactataac
     3901 gatacaagaa gttgttaaca atcttgagca caataaactg ttagcacgta ctattcagta
     3961 tattggtggc gatggcaaac ttacagagac gattgctaac tatagtcaac agttattaaa
     4021 gcaatttctt actgttttga caaatatttt aacatctgtc acggttattg cttctgcaat
     4081 tattaatctt tttattagtt ttgttttttc gttatacgtt ttagcaagta aagaagatct
     4141 ttgtcgtcag ggaaatactt tagtagatac ttatactggt aagtacgcta aacgcattca
     4201 ttacttgtta gagttgttgc atcagcgttt tcacggattt tttgttagtc agaccttaga
     4261 agctatgatt ttaggttcgc tgactgctag tggcatgttt atattaagat taccatttgc
     4321 agggactatt ggcgttttag tagcttttac agcattgatt ccagttatag gtgcttcaat
     4381 tggagcagct attggattta ttttaattat gactcagtcc atgtcacagg ctattatttt
     4441 tatcattttt ttaattattt tgcagcagat tgaaggtaat tttatttatc cgaaagtagt
     4501 tggtggatcg attggatt
//
LOCUS       DAUCXI010000077         4437 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.077, whole genome shotgun sequence.
ACCESSION   DAUCXI010000077 DAUCXI010000000
VERSION     DAUCXI010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4437
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.077"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            4..1278
                     /locus_tag="VGY43_001717"
     CDS             4..1278
                     /locus_tag="VGY43_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEQ4302867.1"
                     /translation="MKKLNVILVGLLSILMLSLAIVFINRWKLNEDSQRIVLAEKKKN
                     TSDLVIKAVKHIKKDQKDYYYFSPIKQADDFFVDNLPVSLYKKKNSDKELILVKPKLQ
                     SSHLRSVNTLTISKIVYQKKFFHLAKKSEKVISTYHVTDDLKPFQVKDLVSGHLERIQ
                     EEVEKKYPNAGFNSDKYNGLKESNSLLSDGFEVKSGNLIFDKKLTIPLTTLFDVINPD
                     FLANSDRAAYDNYRTYKEQHPKKLVALTFDDGPDPTTTPQVLDILAKYQAKGTFFMIG
                     SKVVNNENLTKRVSDAGHEIANHTWDHPNLTNLSVSEIQHQVNMTNQAIEKACGKKPR
                     YLRPPYGATNATVQQSSGLTQMLWTVDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDI
                     HQTTINALPTVMEYLKAEGYECVTVSELYAHQ"
     gene            complement(1388..2473)
                     /locus_tag="VGY43_001718"
     CDS             complement(1388..2473)
                     /locus_tag="VGY43_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEQ4302868.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVNQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFANIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDINNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            2571..3197
                     /gene="udk"
                     /locus_tag="VGY43_001719"
     CDS             2571..3197
                     /gene="udk"
                     /locus_tag="VGY43_001719"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEQ4302869.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            3277..3540
                     /locus_tag="VGY43_001720"
     CDS             3277..3540
                     /locus_tag="VGY43_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEQ4302870.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERNLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK"
     gene            complement(3593..4402)
                     /locus_tag="VGY43_001721"
     CDS             complement(3593..4402)
                     /locus_tag="VGY43_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEQ4302871.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     TEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
BASE COUNT         1493 a          686 c          860 g         1398 t
ORIGIN      
        1 ctattgaaaa aattaaatgt tattcttgtt ggtttattaa gcattctgat gttgagttta
       61 gctattgtgt ttattaatcg ttggaaacta aacgaagata gtcagcgtat agttttggct
      121 gaaaagaaaa aaaacacgtc agatttagtg atcaaagctg taaaacatat taaaaaagat
      181 caaaaagact attattattt ttccccgata aaacaagcag atgatttttt tgtagataat
      241 ttacctgttt cattatacaa aaaaaagaat tcagataaag aattgatttt ggtaaagcct
      301 aaactgcaat cttctcacct aagatcagtt aacactttga ctatttctaa aatagtttat
      361 cagaaaaaat tttttcattt ggctaaaaaa tcagaaaaag ttataagtac atatcacgtt
      421 acagacgact tgaaaccgtt tcaggtaaag gatctagtat caggacattt agaaagaata
      481 caagaagaag ttgaaaaaaa atatccaaat gctggtttta atagcgataa gtacaatggc
      541 ttaaaagaat ctaattcttt attaagcgat ggctttgagg taaaatcggg aaaccttatt
      601 tttgataaaa agctaacgat acctttgacg acattatttg atgttattaa tccagatttt
      661 ttagcaaata gcgatagagc tgcgtatgat aattatagga cctacaaaga acagcatccc
      721 aaaaaactag ttgcattaac gtttgatgat ggtccagatc cgacgacgac tcctcaagtt
      781 ttagatattt tggcaaaata ccaggctaag ggaactttct ttatgatagg ttcaaaagtt
      841 gtgaataatg aaaaccttac taaacgtgtt agcgacgctg gccatgaaat tgctaatcat
      901 acttgggatc atcccaatct gactaatctt tcagtcagcg agattcaaca tcaagttaat
      961 atgacgaacc aggctattga aaaagcttgt ggcaagaaac ctcgctattt acgccctcca
     1021 tacggagcta caaatgcaac tgttcagcaa tcctcaggat taacacaaat gctttggacg
     1081 gttgatacaa gagattggga aaatcatagc actgatggca ttatgactaa tgtcaaaaac
     1141 caattgcaac cgggaggagt tgttttaatg catgatattc atcaaacaac tatcaatgct
     1201 ttgccgacag ttatggaata tctaaaagca gaaggatacg aatgtgtgac tgtatcagaa
     1261 ctctatgcgc atcagtaagt aatatcgtta tgtttcttta gaattgatat actaaacaat
     1321 ccaattactt tgaagtaatt ggattgttgt ttttagtagc ccttgattaa gttttgtttt
     1381 ttaacaacta gttgatgaaa tgaagttgtt gatttttgag ggagatttca gagactttag
     1441 caaatttttt caattttttg aggtcttcag ggtggctaac aaaggtaata acgataccag
     1501 attttcccat acggccggtt cgtccagctc tgtgagtata attttcctta tcacgagcaa
     1561 catcaaaatg aatgacatag tcaagattat taatatcaat gccccgagca acaagatccg
     1621 tagctaacaa taaggagagt tggtgggatt tgaatttttc gagaatggtt ttacggaatt
     1681 tgacattgat gtcactcgct aaggaaaccg cagcagctcc attatactgg agacgttctt
     1741 ccgtagcacc caaatcagat aaactgttga aaaagaccaa agctctaaaa tgaggaatat
     1801 tagcaaattt tcgtaataaa tctgtacgtt cgcgcttgtc aaccatgagg taaaaatgct
     1861 gaatagcatc gttggtttgc tctgaaagat cgatgcagaa tgtatttgga gctaaggaag
     1921 tttgattcac cttattagta gcactcatgt ataccatttg atgatctcga ggaacatagt
     1981 ggctaatttt ttgaacaaaa tcatattggg aatcacctaa tagttcgtca tattcatcta
     2041 aaacaatggt gttgacagac atcatcttga tttttttcaa tttaatcagt tcaaaaatgc
     2101 gtccaggggt cccaatcagg atttcaggac cttttttgag gcgttcgatt tgacgttttt
     2161 gactggttcc agaaataaag agttgtgccg ttaagcctag tggctgtgcc caatcctttg
     2221 tgacttcaaa aatttggcca gctaattcgg tattaggggc taaaatgagt agttgttggg
     2281 actttttagg cgtcagtgcc aatagactag gaaagacata agctaaggtc ttgcccgtcc
     2341 cagtagggct aataccaagg aaatttttac catcaacaat aggttgaaag gcctgttctt
     2401 ggattggcgt taaatgggta aatgcaactt ggtcaagttt ttcttgccat tgagggggaa
     2461 atttagtgat catgcgtctt ccttttacta ttgtttctat attcattata gcattatagt
     2521 ctcaattttg gtaaaataat gagaaagact ttttagattt ggagtttaaa atgcttaaaa
     2581 aaccgattat tattggtgta actggtggtt caggtggcgg taaaacaagt gtgtcacgcg
     2641 ctattttgga cagttttcca aatgctcgta ttgcaatgat tcaacacgat tcttactata
     2701 aagatcagtc tcacatgagt tttgaagaaa gggtcaagac caattatgac catcctctag
     2761 cttttgatac agattttatg attcagcaac taaaagaatt attagctggt agacctgtag
     2821 atattcctat ctatgattac aaaaagcata cccgcagtaa tacgaccttt cgtcaggatc
     2881 ctcaggatgt tattattgtt gaaggtattc ttgtcctaga agatgagcgt ttgcgagatt
     2941 tgatggatat caagcttttt gtagacacag atgacgatat tcgtattatt cgtcgtatta
     3001 agcgtgacat gatggaacgt ggcagaagct tagaaagtat tattgatcag tacacaagcg
     3061 tggtaaagcc tatgtatcat cagtttattg agccaagtaa acgctatgct gatattgtta
     3121 ttccagaggg agttagtaat gtcgttgcta ttgatgttat taatagtaaa attgcgagta
     3181 ttcttggaga agtatagtgg aagtggctga gtagattatt taaatctgct cttttattgt
     3241 tgtgctcttc atagagaaag ggatcataaa atagaaatgt tattaatttg gcttggatta
     3301 ctatttgttt ggaatgaact cgtgtttgtc atatatgcct ttgataaaag aaaagccata
     3361 aaaaagaaac ggcgtattag tgaaagaaac ttattagtga taacagtttt gtttggaggt
     3421 tttggagcat tacttgcagc taaaaagtac caccataaaa ccagaaagtg gtactttgtc
     3481 atcacttggt atactagtat tttgttgaca ttactagtaa cttatatctt tatgaagtga
     3541 gtcacttaaa agacccttaa tcagtattat ttagtcaagg ctcttttata gtttaaaaaa
     3601 gcacatcatc gtcaagggtg ttgatttttt gaaaaagatc accaaagatt aaaaggatta
     3661 atgttcctag taaaactgtc atgccaggaa tgcttgttag aggagagttc cagatgaaat
     3721 gtagcaccag aggacttaat aaccagaaaa tttgttgctg ttttgaaaaa aggttagaac
     3781 cctttaataa taagtatgct ccaatggtaa aaatagctgt atgtacccaa tgtgaagtca
     3841 cagcagtgct aatacgttca atagcagtcg gtacgagact atctatagat tttgcttgaa
     3901 tcaaataacg gatatcttct gttagttgaa agcccatgcc agaaagtaaa gcaacaacta
     3961 atttttcttt aagagtaagt ctaggaaata aagtaattac taaaatagcc gaagaagcct
     4021 taatgggctc ttcgacaata ggggcagtta aagcatctcc ccaaagcttt aaagcgtctt
     4081 tagaagggat gatgtatgac caaaattgtc ctacgagatg gttcccacaa gaagctaaaa
     4141 aacctgaaat ataaagtccg ctaagacagc taacaataat aacattcagg ttcatatgaa
     4201 attttttact taaataaaaa atagctgctg caaatggaat taagtaaatg cctaatagac
     4261 taatggttag tattagagca aaagcttctt taaaggaaag gttgttagct gtcagtccta
     4321 acaattcaag ttcaatacca tttaaaacta aagcaataaa aagaccgtat cgtaaccatt
     4381 tctgttgagt gatttgtttc acgaaaacct cctaatatta agatgatatt aataata
//
LOCUS       DAUCXI010000078         4395 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.078, whole genome shotgun sequence.
ACCESSION   DAUCXI010000078 DAUCXI010000000
VERSION     DAUCXI010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4395
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.078"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            81..332
                     /locus_tag="VGY43_001722"
     CDS             81..332
                     /locus_tag="VGY43_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEQ4302872.1"
                     /translation="MFYLIMAVLIISYYLYMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
     gene            688..2046
                     /locus_tag="VGY43_001723"
     CDS             688..2046
                     /locus_tag="VGY43_001723"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEQ4302873.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPG
                     RHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
                     DA"
     gene            2046..3128
                     /locus_tag="VGY43_001724"
     CDS             2046..3128
                     /locus_tag="VGY43_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEQ4302874.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLMAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ATKEIQSPDFFYDLLRADISFAIKEK"
     gene            3129..4277
                     /locus_tag="VGY43_001725"
     CDS             3129..4277
                     /locus_tag="VGY43_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEQ4302875.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTTKPKKPKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLT
                     SPGQYERPILRTIPWVKSVHLSYQFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMHDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQTPPSPETVLEQAHG"
BASE COUNT         1428 a          776 c          898 g         1293 t
ORIGIN      
        1 tttaagaaaa gtcatttttt aaaggtcttt ttgcgtttac aagttcctat ggaatataaa
       61 ccaaaataaa ggaggacgga atgttttacc ttattatggc tgtcttgatt atatcttatt
      121 atctatacat ggctcctaaa agtgtccgta acacccttgg gatgattggt ttagttggct
      181 tggttgctct gcttattgtt ttagcgggct tgagttttat caaaatcatg caaacccctc
      241 ctgaattttt tattgggatg ggaatggtgg cattgggcta ttttgcttta aaagatgtgc
      301 gtaaaatgac caaaaaaccg agagttaaat aaaagtactt aaagattgat gattttggtt
      361 tttatacgat aaaaggactg atttgtttta gacaatatca gtcctttttt aatagttcat
      421 tttttctgaa agaaagcttt tagccgattt tcattgagtg tgcaactaaa aagagatgtt
      481 tggtaataat agttaagacc tctgactagt attttatctt attttactta aaaaaacgta
      541 ccaataatct cacaaatatg ggcatgatgt ttgtatattg gaaacggatt ctaattctca
      601 actcaagaac ggtattttta aaatgttgaa aaagcatcta aataaaggta aaatagaaat
      661 caaatagaat ggatagtgtg agcttagatg aaagtgataa gtaattttca aaacaaaaaa
      721 atattaatat tggggttagc caaatcaggc gaagcagcag caaaattatt gactaaactt
      781 ggtgctttag tgactgttaa tgatagtaaa ccatttgacc aaaatccagc ggcacaagcc
      841 ttgttggaag aggggattaa ggtcatttgt ggtagccacc cagtagaatt attagatgag
      901 gactttgagt acatggttaa aaaccctggg attccttatg ataatcctat ggttaaacgc
      961 gcccttgcaa aggaaattcc catcttgact gaagtagaat tggcttattt cgtatctgaa
     1021 gcccctatta tcgggattac aggatcaaac gggaagacaa ccacaacgac aatgattgcc
     1081 gatgttttga atgctggcgg gcaatctgca ctcttatctg gaaacattgg ttatcctgct
     1141 tcaaaagttg ttcaaaaagc aattgctggt gatactttgg tgatggaatt gtcctctttt
     1201 caattagtgg gagtgaatgc ttttcgccct catattgctg tcatcactaa tttaatgccg
     1261 actcacctgg actatcatgg cagttttgag gattatgttg ctgctaaatg gatgattcaa
     1321 gctcagatga cagaatcaga ctaccttatt ttaaatgcta atcaagagat ttcagcaact
     1381 ctagctaaga ccaccaaagc aacagtgatt cctttttcaa ctcaaaaagt ggttgatgga
     1441 gcttatctga aggatggtat actctatttt aaagaacagg cgattatagc tgcaactgac
     1501 ttaggtgtcc caggtaggca caacattgaa aatgccctag caactattgc agttgccaag
     1561 ttatctggta ttgctgatga tattattgcc cagtgccttt cacattttgg aggcgttaaa
     1621 catcgtttgc aacgggttgg tcaaatcaaa gatattacct tctacaatga cagtaagtca
     1681 accaatattt tagccactca aaaagcttta tcaggttttg ataacagtcg cttgattttg
     1741 attgctggcg gtctagatcg tggcaatgaa tttgacgatt tggtgccaga ccttttagga
     1801 cttaagcaga tgattatttt gggagaatcc gcagagcgta tgaagcgagc tgctaacaaa
     1861 gcagaggtct cttatcttga agctagaaat gtggcagaag caacagagct tgcttttaag
     1921 ctggcccaaa caggcgatac tatcttgctt agcccagcca atgctagctg ggatatgtat
     1981 cctaattttg aggttcgtgg ggatgaattt ttggcaacct ttgattgttt aagaggagat
     2041 gcctaatgcc taagaagatt ttatttacag gtggtggaac tgtaggtcat gtcaccttga
     2101 acctcattct cataccaaaa tttatcaagg acggttggga agtacattat attggtgata
     2161 aaaatggcat tgaacataca gaaattgaaa agtcaggcct tgacgtgacc tttcatgcta
     2221 tcgcgacagg caagcttaga cgctattttt catggcaaaa tctagctgat gtttttaagg
     2281 ttgcacttgg cctcctacag tctctcttta ttgttgccaa gcttcgccct caagcccttt
     2341 tttccaaagg tggttttgtc tcagtaccgc cagttgtggc tgctaaattg cttggtaaac
     2401 cagtctttat tcatgaatca gatcggtcaa tgggactagc aaacaagatt gcctacaaat
     2461 ttgcaactac catgtatacc acttttgagc aggaagacca gttgtctaaa gttaaacacc
     2521 ttggagcggt gacaaaggtt ttcaaagatg ccaaccaaat gcctgaatca actcagttag
     2581 aggcggtgaa agagtatttt agtagagacc taaaaaccct cttgtttatt ggtggttcgg
     2641 caggggcgca tgtgtttaat cagtttatta gtgatcatcc agaattgaag caacgttata
     2701 atatcatcaa tattacagga gaccctcacc ttaatgaatt gagttctcat ctgtatcgag
     2761 tagattatgt taccgatctc taccaacctt tgatggcgat ggctgacctt gtagtgacaa
     2821 gagggggctc taatacactt tttgagctac tggcaatggc taagctacac ctcatcgttc
     2881 ctcttggtaa agaagctagc cgtggcgatc agttagaaaa tgccacttat tttgagaaga
     2941 ggggctacgc taaacaatta caggaacctg atttaacttt gcataatttt gatcaggcaa
     3001 tggctgattt gtttgaacat caggctgatt atgaggctac tatgttggca actaaggaga
     3061 ttcagtcacc ggacttcttt tatgaccttt tgagagctga tattagtttc gcgattaagg
     3121 agaagtaaat ggcaaaagat aaagagaaac aaagtgatga caagctcgtt ttgacagagt
     3181 ggcaaaagcg taacattgaa tttttaaaga aaaagaagca gcaagctgag gaagaaaaaa
     3241 aactcaaaga gaaattattg agtgataaaa aagcgcagca gcaagctcaa aatgcttctg
     3301 aagcagttga gcttaaaact gatgagaaaa ctgatagtca ggaaattgag tcagaaacga
     3361 cgacaaaacc taaaaaaccc aaaaaagtta gacaacccaa ggaaaaaagc gcgacacaaa
     3421 tcgcttttca aaaatccttg cctgttcttt tgggggcgct cttactcatg gcggtgtcta
     3481 tttttatgat cactccttat agcaaaaaga aagagttttc tgtaagagga aaccatcaaa
     3541 cgaaccttga cgaattaatc aaagctagca aagtcaaagc atctgactat tggttaacgt
     3601 tgttaacttc gcctggtcag tatgaacgac cgattcttcg tactattcca tgggtgaaat
     3661 ctgtacatct ctcttaccaa tttcctaatc actttctatt taacgttatt gaatttgaaa
     3721 tcatcgctta tgcacaagtc gaaaacggtt ttcagcctat tttggagaat ggaaaacgtg
     3781 ttgacaaggt cagggcatca gaactaccga aatctttctt gattcttaat ttaaaagatg
     3841 agaaagcgat ccaacagtta gttaagcaat taacgacatt acctaaaaaa ttagtcaaga
     3901 atatcaagtc agtgtctctt gcaaattcca aaacgacagc ggatttacta cttattgaaa
     3961 tgcatgacgg taatgtagtt agagtaccgc agtcacaact cacattgaaa cttccctatt
     4021 atcaaaaatt gaaaaaaaac cttgaaaatg atagtatagt ggatatggaa gttggaattt
     4081 atactacaac acaggagatt gaaaatcaac ctgaagttcc tcttacgcca gaacaaaacg
     4141 cagctgataa agaaggagat aagcctggtg aacatcagga acagacagac aatgattcag
     4201 agacgccagc aaatcagagt agtcctcagc aaacaccacc atccccagaa acggtcctcg
     4261 aacaggctca tggctagcta atatctaagt tgaaaaagca atgaaaacgt tagaaattca
     4321 acgattctaa cccataatga attgcctaaa aaaaattaag tttatataac aaaaaacgta
     4381 aaatgataac atttt
//
LOCUS       DAUCXI010000079         4386 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.079, whole genome shotgun sequence.
ACCESSION   DAUCXI010000079 DAUCXI010000000
VERSION     DAUCXI010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4386
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.079"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(167..298)
                     /locus_tag="VGY43_001726"
     CDS             complement(167..298)
                     /locus_tag="VGY43_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEQ4302876.1"
                     /translation="MTIKNQKKYKGVYCDKNGKIFYQADLGVDPVTGKRVQKKARKN"
     gene            complement(301..522)
                     /locus_tag="VGY43_001727"
     CDS             complement(301..522)
                     /locus_tag="VGY43_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEQ4302877.1"
                     /translation="MNIGFLEHTARDIIREAKRIAIKKFEEAREIDQNAVQLSKSPFD
                     NRRLGIAPKDIVEELIGILLSEESLESEN"
     gene            609..752
                     /locus_tag="VGY43_001728"
     CDS             609..752
                     /locus_tag="VGY43_001728"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302878.1"
                     /translation="MGISPTGLLRWQPERSEVSLSLFVVMADREPLYFIANNYRSYHG
                     VSH"
     gene            complement(823..1041)
                     /locus_tag="VGY43_001729"
     CDS             complement(823..1041)
                     /locus_tag="VGY43_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4302879.1"
                     /translation="MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADV
                     LVQFSKLYNVSIDYLLGQTDYPYRFHNK"
     gene            complement(1233..1955)
                     /locus_tag="VGY43_001730"
     CDS             complement(1233..1955)
                     /locus_tag="VGY43_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HEQ4302880.1"
                     /translation="MKSYLCSNFLKIKNTSYLLIHILAALLFPLLLFFYWSQRGGLQS
                     RTVLFSYFQIVGVLLPFVASIVCIQLKNLEESSGKYKYLLGYSQSNYKPFIVELVFLW
                     LCYCIVLIISITIFILLLKTIGINVSLRLLILNSLIYIIFAYVTYLINHIISYIFSTG
                     VALGISMVGVIAAAFCETSLGDKVWFLIPWAWLLRISDTLYNQQKMAIVPLIVIFFVS
                     CTVALLHIRIFKSWNQDCLTSS"
     gene            complement(1958..2707)
                     /locus_tag="VGY43_001731"
     CDS             complement(1958..2707)
                     /locus_tag="VGY43_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HEQ4302881.1"
                     /translation="MVQIFLSNLLKIKNTSISKLILIFPIICVMLSLLFSALGGENIL
                     RLTAETTVNQWGVIWINVIIAVNSGLLNKLELDSNKYSVFLSRDVDLKKVEYARVLLI
                     ALINLIISMILSLMLIVISFVLPTPSLISIGRILLTILLIWLTTLWQIPFILWLSRKI
                     NVYFAMIINIISPLIIGTSFSLLNKWYLFPYDWSLKLLEPMTRMRINSIPFGAEFVPD
                     YSQIFISLFLGIAFFILLTNLFAISFKKQVK"
     gene            complement(2713..3402)
                     /locus_tag="VGY43_001732"
     CDS             complement(2713..3402)
                     /locus_tag="VGY43_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HEQ4302882.1"
                     /translation="MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIM
                     KILTGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVS
                     ESTILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIG
                     IQELREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYEGKIILEKEYDGSENLEEL
                     FNNQILFEKRR"
     gene            complement(3408..>4386)
                     /locus_tag="VGY43_001733"
     CDS             complement(3408..>4386)
                     /locus_tag="VGY43_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HEQ4302883.1"
                     /translation="YRFVSLRGIEQGESIFKDNLGNYNTEIVVPILKESNGINNTNDN
                     VQFKNEVKKIYLPFCDWLFFKFYGPKERQEELLNNWKKFWLNLPSELFSQSNMFYMRY
                     NDTNDHIRIRINCDSIENNFSLYLSVVQDLLPQLIESCIISDIEVSSYKPEVNRYGGP
                     HLISYAEEIFCKESILFLNNTIEFSDDERLVCATYLVLYYLNHFFKDKETRRSFLFEN
                     YTGKYKKDFKNLPIDLPIEYMKILNGVTSALDRYDFFQEMDRYLMSYMKEYNRFGGTN
                     DIYNTKFNLVGSFLHLSMNRLNGIDREFEEKVYCFAYYTLNAQQYIEWE"
BASE COUNT         1538 a          775 c          556 g         1517 t
ORIGIN      
        1 aagttacagc ctgaaccttt tgcttatatg ctcttaggta aatagtattc atatagtttt
       61 caaacgatat attgtcattt tcaatactaa gattattact aaacccatac ctaatccgaa
      121 ccagttcatc atacgcttct ttcattgtgc caaatggctc tccatactaa ttctttctgg
      181 ctttcttttg aactcgttta cctgttactg gatctacacc aagatcagct tgataaaata
      241 tcttaccatt cttatcgcaa taaacacctt tgtacttttt ttgatttttt atagtcatct
      301 ttaattctca ctttctaaac tttcttcaga gagtagaata cctattaact cttctacaat
      361 atctttagga gcaataccaa gtcttctatt gtcaaagggc gatttactta attgtaccgc
      421 attttggtca atttcgcgag cttcttcaaa cttttttata gctattcttt ttgcttctct
      481 aataatatct cttgcagtat gttcgagaaa accaatattc atcaagcttt ttatatgtta
      541 ctattttcac acctccactc ctttcaaaaa aattgcaacc tccgtgggta tgactggtta
      601 aatcactcat gggaatctca cccactggcc ttttacgctg gcagcctgaa cgttcagaag
      661 tatcattgtc cctatttgtg gtcatggcag atagagaacc actctatttt atagctaata
      721 attatcgctc ctatcacggc gtatctcact aaattgctcg acaaacaaga aagtcccacc
      781 tcggtttatt cagttgtcaa tgaacaaatc aaggcgagac ttttatttat tatgaaaacg
      841 atacggataa tctgtttgcc ctaataaata atcaatactg acgttataga gtttagaaaa
      901 ctgcacaaga acatctgcca ttaaggcaac ctctcctctc tcaatttttg cataatttgc
      961 atgagagaag gaaagtaaat ttgcaacaaa cttttgagtg aaatcgttat cttctctcaa
     1021 attcctaata cgcggataca tctaacattc tcctaatatc agtataaagg agatttgatt
     1081 aaaaaatgtt taattgtcct atttggacaa gactattaaa tataagctag taatccattg
     1141 aaattttata gtcatttttt agttaaacaa gttagatagt atttataact taaaaaatca
     1201 tatttattgc taggtaaaca aaatagatgt atttaactac ttgtcaaaca gtcttgattc
     1261 caacttttaa atattcgtat atgaagtaaa gctactgtgc atgaaacaaa aaatataaca
     1321 ataagtggaa caattgccat tttctgttgg ttatatagag tatctgatat tcttaaaagc
     1381 catgcccatg gaataagaaa ccatacctta tcaccaaggc tcgtttcaca aaatgctgca
     1441 gcaataacac ctaccattga aatacctaat gccacacctg tactaaatat atagctaata
     1501 atatgattga tcagataggt tacataggca aaaatgatat aaattaaact attcaaaata
     1561 agtagtctga gagatacatt tataccaata gttttcaata aaagaataaa tatagtaatt
     1621 gaaataatta atactataca atagcataac catagaaata ctaattctac aataaatggc
     1681 ttataattcg actgtgagta acccaataaa tatttatatt ttccagatga ttcttctaaa
     1741 ttttttagtt gaatgcacac aatacttgca acaaaaggaa gaagtacacc tactatttga
     1801 aagtaggaga ataatacagt cctgctttgt aaacctccac gttgactcca atagaaaaat
     1861 agaagtaagg gaaataatag tgcagctaaa atatgtatta gtaaatatga agtatttttg
     1921 atttttaaaa aattagaaca taaatatgat ttcatgacta tttcacctgt tttttgaaag
     1981 agatagcaaa tagattggtc agtaagatga aaaaagcaat tcctaggaac aatgatataa
     2041 aaatctgtga gtagtctgga acaaactccg ctccaaaagg tatactattt attctcattc
     2101 ttgtcattgg ctcaagcaac ttcaacgacc aatcataagg gaacaaatac catttattta
     2161 agagagaaaa acttgtacca ataattagtg gagatataat attaataatc atagcaaaat
     2221 acacattaat ttttcttgat agccataaaa taaacgggat ttgccatagt gtagtcaacc
     2281 aaattaacaa gatagttaat agtatcctac ctatactaat aagacttgga gtaggtagga
     2341 caaaactaat tacaataagc attaagctta aaatcatact aattattaga tttataagag
     2401 ctatcaatag aactctggca tattctacct tttttaaatc aacatccctt gataaaaaaa
     2461 cagaatactt attagaatct aattctaatt tatttaacaa accagaattt acagcaataa
     2521 taacattaat ccaaataact ccccactgat ttactgttgt ttccgcagtt aaacgtagga
     2581 tattttcacc acctaatgct gaaaacaata aagataacat cacacaaata atagggaaaa
     2641 taagaatcaa cttgctaata ctcgtatttt ttatttttaa taaatttgat aaaaaaattt
     2701 gtaccatagc ccctacctcc tcttttcaaa taaaatttga ttattgaata actcttcaag
     2761 attctcagag ccgtcatatt ctttttccag aataatcttt ccttcataga taaatccaat
     2821 aaaatcagct agatgttcaa cttctgacag tatatggctt gaaatcataa ttgtcattcc
     2881 ttctgattta aatgactcta taatttccct taattcttga attccaattg ggtccaagcc
     2941 attagtaggt tcgtctaata taagtagttt aggtgaattt attaaagaga tagctatacc
     3001 taaccgttgc ttcattccaa gagaaaattg ttttactggt ctcttgtcaa tatttcctag
     3061 accaacttta tttaataatg gaagtatagt gctttctgaa acaccaagca ttgttgtaac
     3121 taccttcata ttatcgtaag cactcaaatt tttataaagt ggtggttctt caataatact
     3181 cccgattttt cgcagatccc gacgtgacca ttctctacct tcaaaaataa tagaaccact
     3241 tgtcttacta actaagcctg tcaaaatttt cataatagtt gattttccag caccatttgg
     3301 accgattaaa gcatacactt ttcccttagg aatattcata ttgacattat tcaatatggt
     3361 tctcttacca taagattttt ttagattttg tattttcaac atattagtta ctcccattct
     3421 atatattgct gagcgtttag tgtatagtaa gcaaaacaat acactttctc ttcaaactct
     3481 ctatcaatcc cgtttaatcg attcattgat agatgtaaaa aacttcctac taaattgaat
     3541 ttagtattat agatatcatt tgtaccacca aatcgattat actctttcat ataagacatg
     3601 agatatctat ccatttcttg gaaaaaatca tatctatcaa gagctgaggt gactccattc
     3661 aaaatcttca tatactcaat aggtaaatca attggcaaat ttttgaaatc tttcttatac
     3721 tttccggtat aattctcaaa taagaaagag cgccttgttt ctttatcttt gaaaaagtga
     3781 tttagataat atagaaccaa gtaagtagca caaactaatc tttcatcatc tgaaaattct
     3841 attgtattat taagaaataa gatagattct ttacaaaaaa tttcctctgc ataacttatt
     3901 aaatgaggtc ctccatatct atttacttct ggtttatagc tactcacttc tatgtcagag
     3961 ataatacaac tctcaatcag ttgaggtaat agatcttgaa ctactgacaa atacaaagaa
     4021 aagttatttt caatcgaatc acaatttatc cgaattctta tatgatcatt ggtatcatta
     4081 tatctcatat aaaacatgtt actttggcta aacagttctg atggcaggtt tagccaaaat
     4141 tttttccagt tatttagtaa ttcttcttgt cgctcttttg gaccataaaa tttgaaaaat
     4201 agccagtcac aaaatggtaa atatattttc ttaacttcat ttttaaattg aacattatcg
     4261 tttgtattgt ttattccatt agattcctta agaattggaa ctactatctc tgtattgtag
     4321 ttccctaaat tatccttaaa aatagactct ccctgctcaa ttcctctcaa agaaacaaac
     4381 ctatat
//
LOCUS       DAUCXI010000080         4169 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.080, whole genome shotgun sequence.
ACCESSION   DAUCXI010000080 DAUCXI010000000
VERSION     DAUCXI010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4169
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.080"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            458..1966
                     /locus_tag="VGY43_001734"
     CDS             458..1966
                     /locus_tag="VGY43_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEQ4302884.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKMLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRPFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIANFITSTIPSYKVELSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLFGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            complement(2315..3664)
                     /locus_tag="VGY43_001735"
     CDS             complement(2315..3664)
                     /locus_tag="VGY43_001735"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEQ4302885.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKEEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
BASE COUNT         1255 a          819 c          724 g         1371 t
ORIGIN      
        1 aactagctct ctcaaaaaag attaaaaata aaggcattct aaagaatcat ttaagaaaac
       61 tttaaggtta ctatcgtaga atgaaaacat cctaaaaagc ggtttaccta aaccgttggg
      121 agaataggtt ttccccttgt tttccctttt cataaatctc ctgggcacct atcttcttag
      181 gtgccctccc ttgtttaaac ctgaccagtt aaccggctgg ttaggttttt aaatttaaaa
      241 agtcaacagc aaaaatatga tatcacccgc gtgttcttag ctctctcaat tatgggctaa
      301 aaacacgcat caatcaatct attgatgaag tttgctgctt tttgatgatc tttattgtga
      361 ctatactggt aatcctattg attttagttg acttttacgg tagattcgct acaatatata
      421 ggattataca atttaattta aggagagaaa aattacattg ttagattatt atttggaatc
      481 cgatattatt gaccagaaaa tcctactggc tattttgttg acagaaaaag aactgacgat
      541 ggcagcagct tgttctcaaa caactttgac tgctttaaaa ataaagcagt atcttcgaca
      601 atttaacgcc ttatttaaag ggtacttacg tattgagctt attaaatctc gtatttattg
      661 tgaggtatta aatgataagc gagaagcatt tttttatgat atttttgcct tatcagatac
      721 tctaaaaatg ttgacattct tattactaga taatcccaaa cacaaatcaa tcgctgttta
      781 tacacgaaaa caagggatat cccagtcaaa agcttatcgt cttattcata aattaaaaca
      841 ttatttacaa gacattggtt taaatattgt agacaatact gttatcggag atgaacttaa
      901 aatacggtat ttgattgctc ttttacataa agagtacggc attatattat atgatataca
      961 acctgcagac attgaaacga ttcatgcttt tatctttgca gcacaaaaaa acttacaacc
     1021 ttctgccttt ttagatagac ccttcttgtt ttttgatgtg ctgttgatgt tgacttggaa
     1081 gcgccatcgc tatcctgttc atttgcctca tttagctctt tttgaacatc tcaaatcctt
     1141 gcctattttt gacaatatca aaaccattgc cgtggatgag ctagcacctc gaactcgtgt
     1201 cacattttcg tctgatgatt ttgactatct ctttttaatt tatttaacga ctgataactc
     1261 cttcttgagt gggtactgga caagtcatca gcgacaacaa ctttaccatt taatcaccaa
     1321 agatcccgat tatcatttac taatccatcg tcttcaggca ctagttggaa aatattccga
     1381 tattcatgag catatcccta acttaattcc ttttttcaaa agaactctct acaatttaca
     1441 aactttaatt acctttgatg gttattattt tgatcaatat caaggtaaca tgctactact
     1501 agataagctt gaaaccgtta tcaaagactg gctttatgac acaggccgtc aaggcagtat
     1561 tagttctggt cacttacact tgatgtgttt ataccttgag cagatcttgg aaagctctat
     1621 tgctccaatc aatattactg ttattgagag ccaagaaact gttggtaacg ttatagctaa
     1681 tttcatcacc tcaactatcc cttcttacaa agttgaactg tcacgggtca atatcttatc
     1741 tgataatatt tatccctatg ataaacctgt agatctggtt gtaaccagtc agaagctctt
     1801 gcctttctta aaagaactcg gtgtttttcc caaagagacc cgcttgtttg gtttgagttt
     1861 ggactgtatc caacagcagc gcgaagattt aatcaaaacc atcttagcct tgcaccagaa
     1921 ccactaccaa aaacgtttag aagaactttg gagagttcct tcttaatttt ttgacagtcc
     1981 ctcctagata ctttcacagt ctaggggggt ttttaaggtt gtcacttgca accttgataa
     2041 gctctctttt taaccattgc tattcgccta gaaacagcac tggaactgtt ttagcggttc
     2101 aactcctctt gtaggatctt cttccctttt ttgaaggtct tatctgaaat ttggcataat
     2161 aaagtgcgct cccatgttct ggaagcgcac tttattatcg cttttactta accttgtatc
     2221 cactcgatga tggaagtgcc gccccaattc ttagattgct tggctaactt ttaagctctt
     2281 gtacaaggaa gaagtctttt tgactatctg ttgattagag gcgagcatta agctctgctg
     2341 ataatgcttc aaaacctggt tttccaagaa gcgcaaacat gttacgtttg taagcttcaa
     2401 cacctggttg atcaaatggg ttgacagcat tcatgtagcc tgaaacagcg atggcaagct
     2461 caaagaagta aatagtgtaa ccaagggtaa actcgtcttg agctggaaga gtgacaaaca
     2521 tgtttggcac gccgccatct gtgtgggcaa gaagcacacc atctgtagct ttcttgttaa
     2581 caaaatcaac gtctttacct tgaaggtaac caagaccatc taggtcttct gctaattcag
     2641 gaatgataac atttttacga ggattatcaa cacgaataac tgtttcaaag agattacggt
     2701 aaccttcttg gataaattga ccaagtgagt gaaggtctgt tgagaagtta gctgaagttg
     2761 ggtaaatccc tttttggtct tttccttctg attcaccagc taattgtttc caccattcgc
     2821 caaagtactg aagagatggc tcgtagttag ccaagatttc agtgatgtag cctttacggt
     2881 aaagcacatt acgaacagca gcgtattggt aagcaatgtt ttcagagatt ttgtctgaag
     2941 aaaggtcttt acgagcagca tttgcccctt ccataagagc agtaatatct gcacctgatg
     3001 cagcaattgg aagcaaacca acagcagtca agactgagaa acgaccacca acattatctg
     3061 gcaccacaaa tgtttcccag ttgttagcgt cagcttctac cttaacagca cccttaactt
     3121 tgtctgtggt agcgtagata cgtttgttag cttcttcttg gccatatttt ttaaccaaaa
     3181 gttctttgaa cacgcgaaag gcaatagctg gttcagtggt tgtacctgat ttagagatca
     3241 cgttgactga gaactctttg tcttgaacgt actcaactaa atcggcaagg taagtagatg
     3301 aaatagagtt tccagcgtaa agaatttgtg gggctttgcg ctctttggca gtttgcaagt
     3361 tagcaaaatg atgatttaaa aaatcaatcg ctgctttggc accaaggtat gacccaccga
     3421 taccgatcac cacaagaact tcgctgtctg ccttaatctt ttcagcagca gtcaagatac
     3481 gtgcaaattc ctctttgtca tagttttctg gaagatcaag ccagcccaag aaatctgaac
     3541 ctggtccagt tccttcacgc aataacttgt cagcttctgt tacttgacct tgtaaaaaat
     3601 caatttcatg ttgtcccgca aatgactcga ggacttttga ataatcaaat gtaatatgtg
     3661 acatgagttt cgctccctta aaattttaag tttcattagt atgataacct tttctatcta
     3721 atatttcaat ggtttttagt ggttttcacc tgtgaaaaag ctaggttttt tgaaaaggtt
     3781 ttcgtttttt cagacataaa aaatgtgtca atgcaagcat attctcatca tagtggtttt
     3841 ttaagagaaa ataggatttc atatttccta aaaatatcat gaaaaaaggc tctgaggccg
     3901 ctttacctta ataacttatt ttaaggattt tatcatttca atacgggtaa taaccccatc
     3961 atgcatatga tcaatgcata aggccacacc cgcaaaggca attgaagccc caatcacctg
     4021 taaatacttt ctcatgctat cttcttaaca ttacttactc tcattatcta aaaatggcaa
     4081 ttctttgaat acttaaaaag caaagggggg agaatagcac tagtacgttt ttaagtagat
     4141 atcaaaatga ctaatttctt cactattaa
//
LOCUS       DAUCXI010000081         4092 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.081, whole genome shotgun sequence.
ACCESSION   DAUCXI010000081 DAUCXI010000000
VERSION     DAUCXI010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4092
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.081"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            84..422
                     /locus_tag="VGY43_001736"
     CDS             84..422
                     /locus_tag="VGY43_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEQ4302886.1"
                     /translation="MKSPFTVTNTMLNKVVEISKIIGNLELQVQKDLKLRKENRIQSI
                     HSSLAIEQNSLTVEQITAIIDGKRVLGNPREIREVKNAYEAYEEILTLTPYDESHFLK
                     MKEFQQYIYR"
     gene            446..1270
                     /locus_tag="VGY43_001737"
     CDS             446..1270
                     /locus_tag="VGY43_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine ligase"
                     /protein_id="HEQ4302887.1"
                     /translation="MGLGSDSLPVKISLFDVDTYLADSMQFHLEYILRLFPKSGVHYL
                     MPTFRGEAVDHRHLSQFYHSECEIEGDLHDVMNLVDRYIKFLVSEILRECRDSIFAIT
                     KDVSHLESFIDRKIPIITFEEACTILENEIDSLEYNDEHHFYVLTDVGEKKLMEHFEG
                     VVWVKNYPCKSVPFYQRFSTDHLFAYNADLLLGIGETVGCGERCETYEEVVENMNYLQ
                     VDASEYSWYLEMKKTRPMKSSGFGLGVERLIAWILKCDDVRKVQLISRENGIDYLP"
     gene            1284..2528
                     /locus_tag="VGY43_001738"
                     /pseudo
     CDS             1284..2528
                     /locus_tag="VGY43_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285438.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit family protein"
     gene            2453..3472
                     /locus_tag="VGY43_001739"
     CDS             2453..3472
                     /locus_tag="VGY43_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEQ4302888.1"
                     /translation="MFGKQGIRCARKGDERNIKIIVNRVNSERNIKSIGICSPSYPGT
                     FHYQKRYKRGVEFLQNKGFTIVEGNLTGKEGYRGEISGGVQDRAEELNQLIPRVDVIM
                     TSIGGYNSNSILKYIDYDLFKQKSPIFIGYSDTTALALALYNKTGCITYLSQSVISNF
                     GEFEPFNELNYFYFDFMLQSKCETLMVQIPDVWTDEWINWETYERTKKTNKNEWIIFN
                     KGEFNGTLIGGNLDTIVGIIGTEYMPKITEDTILLLEDVYTDLGRLYRNFTTLALHGI
                     FDKIGGLIISKFETIGENSDVINDIINEFVGHRKIPILLNFDCGHTHPSCLMPIGGKI
                     TLSLS"
     gene            3485..3685
                     /locus_tag="VGY43_001740"
     CDS             3485..3685
                     /locus_tag="VGY43_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302889.1"
                     /translation="MNNRESKLTGFYDVFEEEVEKINHIHNVFVEESEKFGFQQMKIA
                     MVEHRKKYLDATDVHYTKYKNI"
     gene            3805..>4092
                     /locus_tag="VGY43_001741"
     CDS             3805..>4092
                     /locus_tag="VGY43_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302890.1"
                     /translation="MLFRDRIPTYKGYRRQFNQILLGAWGIESAYVDAEIIVATWRGL
                     QRFKGIKVEFIQLSNKNIFDVLEKDLSKKLRFEDISIEAILGKYLCNNDIEI"
BASE COUNT         1532 a          478 c          804 g         1278 t
ORIGIN      
        1 atcgcttgtt ttatcgcttg aagaacgagc gataaattta tttttatggt ataaataaga
       61 aaaaagattg taaggagaaa atgatgaaat caccttttac agttacgaat accatgttaa
      121 ataaggtagt agagatttct aaaattattg gtaatttaga attacaagta cagaaagatt
      181 taaaattaag aaaagaaaat cgtattcagt ctattcactc atcactcgct attgaacaaa
      241 attctttaac agtagaacaa ataacagcca ttattgatgg gaaaagagtg ttaggaaacc
      301 cccgtgagat aagagaagta aaaaacgctt atgaagctta tgaagaaatt ttaacgctaa
      361 ctccctatga tgaatcacat tttttaaaaa tgaaggaatt tcaacagtac atttaccggt
      421 aacaacatcg tcaatcacaa gtcctatggg gttggggagt gattcgctac ctgtaaaaat
      481 ttccttattt gatgttgata cctatcttgc agattcgatg cagtttcact tagagtatat
      541 acttagactt tttccaaagt caggagttca ttacttaatg cctactttta gaggagaagc
      601 agtagatcat cgacatttat cgcaatttta tcatagtgag tgtgagatag agggagattt
      661 acacgatgtg atgaatttag tggatagata tattaagttt ctggttagtg aaattcttag
      721 agagtgtcga gatagtattt ttgctataac aaaagatgta agtcatttgg aaagttttat
      781 tgatcgaaag ataccaatta ttacgtttga agaggcttgt actatattgg aaaatgaaat
      841 agattcattg gaatataatg atgaacatca tttttatgtg ttaacagatg ttggggaaaa
      901 gaaattaatg gaacattttg agggagtagt ttgggtaaaa aattatccct gtaaaagtgt
      961 ccctttttat caaaggttct caacagatca tctatttgcc tataatgcag atttgttgtt
     1021 aggaataggc gaaactgtag gttgtggaga aagatgcgaa acatatgaag aagttgtaga
     1081 aaatatgaat tatttacaag tagatgcttc tgaatatagt tggtatttag aaatgaaaaa
     1141 aacaagacct atgaaatctt caggatttgg tttaggagta gagcgtttaa tagcgtggat
     1201 attgaagtgc gatgatgttc gaaaagttca attaatcagt agagaaaatg ggattgatta
     1261 tttaccataa aggaggaaga aaaatgaaaa agaatatttt aattgtaggt ggaggtccag
     1321 agataactat atgttatgat ttaattaaca atagtacgga gtataatttc ttttcagtat
     1381 cagaaattcc tccgatgtat ccagagttgt ttgtagaaac aattgaaacc agctttagaa
     1441 attttggaaa gacgattgaa caaattaaag agctcaaata ttctattgat gctgttgctt
     1501 gttgggatga agctttaacg catatagctg atgatatttc aaaagaatta ggattgaacc
     1561 ctatttcatc gctagattct caatcattca ggtttaaaga tcgaatgaga atggtatgtg
     1621 aagctggtgg actaaaaatg cccaaatata aaattatcaa tcaattttca gatacaaata
     1681 aaataatcaa ttggaaatat ccattaatag tgaaaccaac ctctttttta gcaagtatag
     1741 gagtgaaaaa agtttataat ttttcagaat tacaacaagc agtttctcaa atgcttaatg
     1801 taaaatttcc ggtttacata gcttcagggg tatatgaatt ggggaattat ataatttaga
     1861 acctagagtt ttggtggaag agtttattga tggagaagaa tatagcttag agagcgtggt
     1921 aagaaatgga atctatacac ctctagggat aactaaaaaa tagtggatga aaaattattt
     1981 atggatgaaa taggccatat tttcccttcc aatttaaaca aagaagaaaa aagtagagta
     2041 tattcttggg cagaaaaatt acatcaaatt ttgcaattaa atcatattac gactcataca
     2101 gaatttagaa ttggaagaaa tggagatatt attttaatag aaattggagc aagaatcggt
     2161 ggagattgta tccaaactta atgaaaaaca gctttatagt caagggattt gatttttata
     2221 atacttattt aaaagctaga ctaggtttac aagaagagtt aaatacagac actaataagt
     2281 tttcaggaat tgtatttttc agactcaatc cagagaatta cggaaaaata tttaatggag
     2341 tgagttacga tgcacctaaa acttcactaa tatttgaaga aaagatgtat aaagaggaag
     2401 gaactgtatt gccaaatccg attaattgga gtaatgagag agtaggatat gtttgtttgg
     2461 aaaacaagga atacgctgtg ctagaaaagg agatgaaaga aatattaaaa tcattgtcaa
     2521 tagagtaaat agtgaaagaa acatcaaatc tataggtatt tgttcaccct cctatccggg
     2581 gacatttcat tatcagaaac gatataagag aggagtagaa tttttacaaa ataaaggatt
     2641 tactatagta gaggggaatt taacaggaaa agaaggttat agaggggaaa tttcaggagg
     2701 tgttcaagac agagctgaag aattaaatca acttattccg cgtgtggatg tcatcatgac
     2761 ttccataggt ggctacaatt ctaattctat attaaagtat atagactacg atctatttaa
     2821 acagaaatct cctatcttta ttggatattc tgacacaaca gctcttgctt tagccttata
     2881 taataagact ggatgtataa cttacctgtc tcagagcgtt atctctaatt ttggagagtt
     2941 tgaaccgttt aatgaattaa attatttcta ttttgacttc atgcttcaga gtaagtgcga
     3001 aaccttaatg gtacaaatac cagatgtttg gacggatgag tggataaatt gggaaaccta
     3061 tgaaagaacc aaaaaaacaa ataaaaatga gtggattatt tttaacaaag gtgaatttaa
     3121 cggtactttg atcggaggaa atctcgatac cattgtagga ataataggaa ctgagtatat
     3181 gccaaaaata acagaggata ccatactctt gttagaagat gtatatacgg atctaggaag
     3241 attatatagg aatttcacaa cgcttgcctt acatggtatt tttgataaaa taggaggact
     3301 tattatttca aaatttgaaa caatagggga aaatagcgat gttattaatg atatcattaa
     3361 cgaatttgta gggcatagaa agattcctat tttattgaat tttgattgtg gtcataccca
     3421 tcctagctgt ttaatgccta ttggtggtaa aattacgttg agtttaagct aaaagaggtg
     3481 gtatatgaac aatagagaaa gtaaattaac gggtttctat gatgtttttg aggaagaagt
     3541 agaaaaaata aatcatattc ataatgtttt tgtagaggag tcagaaaaat ttggctttca
     3601 acagatgaag attgctatgg tagagcatag aaaaaaatac ttagatgcaa ccgatgttca
     3661 ttatacaaaa tacaaaaata tttgaagttc atagagtaaa agaagagtca gtatacgccc
     3721 tccaatcaga tttggcactt agtatgtcgc cgttgtatag ctaacttacc acaacaaata
     3781 cctgtaaagt ggattcaaga cagagtgtta tttagagata gaattcctac atataaaggt
     3841 tatagaagac aatttaatca aatattatta ggtgcatggg gaatagaatc agcttatgtg
     3901 gatgcagaaa taatagttgc aacttggcga ggcttgcaac gatttaaagg aattaaagta
     3961 gaatttattc aactgtctaa caaaaatata tttgatgttt tggagaaaga tttatctaaa
     4021 aagttaagat ttgaagatat ttcaattgaa gcaatattgg gtaaatattt gtgtaataat
     4081 gacatagaaa tc
//
LOCUS       DAUCXI010000082         3929 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.082, whole genome shotgun sequence.
ACCESSION   DAUCXI010000082 DAUCXI010000000
VERSION     DAUCXI010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3929
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.082"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            4..972
                     /locus_tag="VGY43_001742"
     CDS             4..972
                     /locus_tag="VGY43_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3644 domain-containing protein"
                     /protein_id="HEQ4302891.1"
                     /translation="MENLSERLVLKSVEAFIMGLEIYNKPTIKYRIEGFSFFICNAWE
                     LMLKAEMLNRGFSIYYSDNPERTLSLEYVLKKIYSDENTRIRLNLEKIIELRNISTHF
                     ITEDYEIKYAPLFQACVLNLASEMKRFHNKDITESIAHNFLTISESYEPLSNEEIKLK
                     YPSEIAEKFIKQANEVDVLSKEYNSEKFSIDIRQNLYITKKKDEADFVVSISKDAETP
                     VSLVKELKDPSDTHKYSYSNVITAVQERLKKSAIKLGYEKGFNTYVLNLVIDFYNIKS
                     ETKFSYCHLIGSTQTYTYSQQFVEFIVNEIKKDPQNFVESLKKSNK"
     gene            1486..2118
                     /locus_tag="VGY43_001743"
     CDS             1486..2118
                     /locus_tag="VGY43_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302892.1"
                     /translation="MKNTLTLLLVLFAIGVTSSVRADTYGNQRIWGFRTDWEKGRDFG
                     ARPIKKGDSDIKIKTAPEAVLTVKKWENNKWTTIPQKKNTTLSSTEAQKTFSVADGAG
                     LAVFYLGNEHIANIGDKYKVTLTIDGFYLASEEWTVGESLPKDEEERDEAEIQKFIEE
                     LEQRQRESEDQKYAEELFKLSIKEEDHKTWHQRLSESIQDQWWNFKGLFQ"
     gene            complement(2212..2391)
                     /locus_tag="VGY43_001744"
                     /pseudo
     CDS             complement(2212..2391)
                     /locus_tag="VGY43_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2515..3770
                     /locus_tag="VGY43_001745"
                     /pseudo
     CDS             2515..3770
                     /locus_tag="VGY43_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         1411 a          735 c          698 g         1085 t
ORIGIN      
        1 taaatggaaa atttaagtga aagattagtt ttaaaaagtg tcgaagcttt tattatgggg
       61 ctcgaaatat ataataaacc gacaataaaa tatcgaattg aaggctttag tttttttata
      121 tgtaatgctt gggaactaat gctaaaagct gagatgctta accgagggtt tagtatttat
      181 tacagtgata atccagaaag aacattgagc ctagaatatg ttttaaaaaa gatatattct
      241 gatgaaaata ccagaattcg gttaaatctt gaaaaaataa ttgaattaag aaatattagc
      301 acccacttta ttactgaaga ctatgaaatt aaatatgctc cattatttca agcatgcgtt
      361 ttaaatttag cgtcagaaat gaaaagattc cataataaag atattaccga atcaatagca
      421 cataattttt taacaatatc agaaagttac gaacctttat ccaatgagga aataaagcta
      481 aaatatcctt cagaaattgc agaaaaattc atcaaacaag ctaatgaagt tgatgtactg
      541 agtaaagagt ataattctga aaaattttca attgatatta gacaaaatct ttatattact
      601 aagaaaaaag atgaggctga cttcgttgtt agtatttcaa aagatgctga aacccctgtt
      661 tcactagtta aagaattaaa agatccgtca gatactcata aatattccta tagcaatgta
      721 ataacagcag ttcaggaaag gctaaaaaag tctgcgataa aacttggcta tgaaaaaggg
      781 ttcaatactt atgtattaaa tttagtgatt gatttctata atattaagag tgaaacaaaa
      841 ttttcatatt gtcatcttat aggatcaaca cagacttata catattcaca acagtttgtt
      901 gaatttatag taaatgaaat aaaaaaagac cctcaaaact ttgttgagag ccttaaaaaa
      961 tcgaacaaat aaaaaaaccc caggcacata ggaatgctca gtactaagta cctaccccat
     1021 tttgggaccc agcgtttatc cttcacgagt ttttttatta actatattat accacttaca
     1081 aaataaacgt caattattat tgacaaatta attaaaagac accccgtaag gtgccttttt
     1141 tcttgcctgt ggacgccttt ttttatcccc tttttagtgg gacttgtgat ggcctttaaa
     1201 acaggtctat gaaacgattt gtgtgataaa atcctcaatg ctactagata agaaacccta
     1261 tgaaatgcag taactatcta ggatcgagaa tctcttcaaa tgtcatattg ttcttcttta
     1321 tggacgatat ccgttgcgct aataggaact ttagtcagtc tgtctgcccc taccaagaat
     1381 agtcgcgcca tttcccaacc acaagacata aactccctat ctttttagcg caagaattgg
     1441 tataataagc cttgtcttaa aaaatgagca aaaggggata aaaaaatgaa aaatacatta
     1501 accttgctac tggtactctt tgccatcggg gtaactagta gcgtcagagc ggatacgtat
     1561 ggcaatcaaa gaatatgggg atttagaaca gattgggaaa aaggacgaga ttttggtgct
     1621 cgccctatta aaaaagggga tagtgatatt aaaattaaaa cagcaccaga agcagtctta
     1681 actgtaaaaa agtgggaaaa taataaatgg acaactattc cacaaaaaaa gaacaccact
     1741 ttaagtagta ctgaagcaca gaaaactttt tctgttgctg acggtgcagg tttagcagtg
     1801 ttttatctag ggaatgagca tatagcaaat ataggcgaca aatacaaagt aacactcact
     1861 attgatggtt tttacttagc tagtgaagag tggaccgtag gggaatcgct cccaaaagat
     1921 gaagaagaaa gggacgaagc tgaaattcaa aaatttattg aagagttaga gcaaagacaa
     1981 cgagaatcag aagaccaaaa atacgctgag gaactattca aactttctat aaaagaagaa
     2041 gaccataaaa cttggcatca gcggttaagt gagagcatcc aagatcagtg gtggaacttt
     2101 aagggactgt ttcagtgagg gtttgctagg ctatgaggtt agctaaagta caaaaagcac
     2161 ctgtcagggg tgctttttgt gatgttgatt gcgtgcaaag aggggggaag gttagtaggg
     2221 gatgacggtt gggtcatagt aggcataggc cactactgcc atagctagag cagctaagat
     2281 aagcccagct agcgaccaaa ccttttgcct gcctttgttt tgcaccagac cgataagagc
     2341 tagactactt gctacaagcg gcaagtagag ataactataa gtagcaaaaa agggctctat
     2401 aatatctgta gtgggtaact cccctacaga tattataaga ctttttggat gtacacaaaa
     2461 aatcccatat gacttataat gcaaagcgac caaaccatca ttagaaagaa ttatatgaga
     2521 caactctatc atactacaga attgattgga attaaagata aacacatcac cttgaacaag
     2581 gtttttcaac gcgagacacc tatcgaagtc ttcgccacac ttgactatcc cccacctaag
     2641 tgtaaacact gtaaaggagt tcagattaaa tacgactccc agaaacattc taaaatcccc
     2701 tttatcgaaa ttggtggttt ccctagtctc attcgtttaa aaaggagaag atctcaatgc
     2761 aagtcctgtc gaaaagtggc tgtagcggaa acaagtctgg ttcaaaaaaa actgtcagat
     2821 ctctgagcac ctcagacaaa aagtagcaca aaccttggtt aatcgaggcg ctctcactaa
     2881 catcgctcaa cagtcggcta gatcatcctc taccgtctac cgaaaactca accagtttgt
     2941 aatcaaggaa gacttctcta aactactcga ggtgttgtct tgggatggat ttttctatca
     3001 aaagggcgaa ctcgccttta tcgctcaaga ttttgagtcc aaaaaaatca tctccatact
     3061 ggacagccgg cgacaaacaa ccattcgaaa tcacttcttt agatactcta aagaggctag
     3121 aaacagtgtc aaaatcgtta ccgttgatat gtcaggaagc tatatttcgc tcattaaaaa
     3181 gctatttcct caagctaaca tcgtcctaga tcgtttccat attgttcagc acatgaacag
     3241 agcgctcagt caaacccgga ttcacatcat gaagcaatat gacaaaaagt ctctggaata
     3301 cagagttctt aaatactact gtcaactcat tcaaaaggta gccgaaaact ctcgctcaac
     3361 gccttctact ctagaacttt tagggaaaca ctaactccta aacaatgtct caataaacta
     3421 tttaatctcg ttcctgaatt aaaagattac tatgaccttt atcagttact cctttttcac
     3481 ttacaagaga agaatactga gcattttttg acttaattaa aaaggtgtta cttctgctca
     3541 atcacacctt taaaacggct ttgaacaccc tgatgcgata caaaaactat gtcattaatg
     3601 ccattgagct tccttgttca aacgccaaac tagaagcaac caataaactc atcaaacaca
     3661 tcaaacgcaa tgcttttggc tttcggaact ttgataactt taaaaaacgc atttacttcg
     3721 ctttgaacat aacaaaagag aagacgagtc tcgtctcctc acgtgtttag ctataagtca
     3781 cccactacag ttgacaaaga gcccaaaaaa gaagatatga tcaagcaggc agacaaaact
     3841 caccgccatg cttaggacgg gcaacacttt cttttctggc ataaatgctc ctttctcaac
     3901 acacgggtca ctaaaaccca aaaaagcca
//
LOCUS       DAUCXI010000083         3882 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.083, whole genome shotgun sequence.
ACCESSION   DAUCXI010000083 DAUCXI010000000
VERSION     DAUCXI010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3882
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.083"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            196..1455
                     /gene="hasA"
                     /locus_tag="VGY43_001746"
     CDS             196..1455
                     /gene="hasA"
                     /locus_tag="VGY43_001746"
                     /EC_number="2.4.1.212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
                     /protein_id="HEQ4302893.1"
                     /translation="MPIFKKTLIVLSFIFLISILIYLNMYLFGASTVGIYGVILITYL
                     VIKLGLSFLYEPFKGKPHDYKVAAVIPSYNEDAESLLETLKSVLAQTYPLSEIYIVDD
                     GSPNTDAIQLIEEYVNREVDICRNVIVHRSLVNKGKRHAQAWAFERSDADVFLTVDSD
                     TYIYPNALEELLKSFNDKTVYAATGHLNARNRQTNLLTRLTDIRYDNAFGVERAAQSL
                     TGNILVCSGPLSIYRREVIIPNLERYKNQTFLGLPVSIGDDRCLTNYAIDLGRTVYQS
                     TARCDTDVPFQLKSYLKQQNRWNKSFFRESIISVKKILSNPIVALWTIFEVVMFMMLI
                     VAIGNLLFNQAIQLDLIKLFAFLSIIFIVALCRNVHYMVKHPASFLLSPLYGILHLFV
                     LQPLKLYSLCTIKNTEWGTRKKVTIFK"
     gene            1491..2699
                     /gene="hasB"
                     /locus_tag="VGY43_001747"
     CDS             1491..2699
                     /gene="hasB"
                     /locus_tag="VGY43_001747"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="HEQ4302894.1"
                     /translation="MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSP
                     IQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIK
                     EVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYF
                     NELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIP
                     QTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNSDNFRESAIKDV
                     IDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNK
                     VYSRDIFNRD"
     gene            2881..3795
                     /gene="hasC"
                     /locus_tag="VGY43_001748"
     CDS             2881..3795
                     /gene="hasC"
                     /locus_tag="VGY43_001748"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HEQ4302895.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     DILERQTPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PQVKEDLKNYIIKLGKALEKSKVPTHSK"
BASE COUNT         1322 a          646 c          668 g         1246 t
ORIGIN      
        1 ctatttgaaa agtttgctaa aatattttat aacaattcaa ttatcctgat ttttcctttt
       61 tttgggggaa attttttaat ggaaatacat ttttattaaa aatatctcta tgcctagttg
      121 acattatccc ttatttatat tagaatatcg aggtccctgt ctttcaagga aattaaaaaa
      181 gaaagaggtg taattgtgcc tatttttaaa aaaactttaa ttgttttatc ctttattttt
      241 ttgatatcta tcttgattta tctaaatatg tatctatttg gagcatcaac tgtaggaatt
      301 tatggagtaa tattaataac ctatctagtt attaaacttg gattatcttt cctttatgag
      361 ccatttaaag gaaagccaca tgactataaa gttgctgctg taattccttc ttataatgaa
      421 gatgccgagt cattattaga aactcttaaa agtgtgttag cacagaccta tccgttatca
      481 gaaatttata ttgttgatga tgggagtcca aacacagatg caatacaatt aattgaagag
      541 tatgtaaata gagaagtgga tatttgtcga aacgttattg ttcaccgttc ccttgtcaat
      601 aaaggaaaac gccatgctca agcgtgggca tttgaaagat ctgacgctga cgttttttta
      661 accgtagatt cagatactta tatctatcca aatgccttag aagaactcct aaaaagcttc
      721 aatgataaga cagtttatgc tgcaacagga catttgaatg ctagaaacag acaaactaat
      781 ctattaacgc gacttacaga tatccgttac gataatgcct ttggggtgga gcgtgctgct
      841 caatcattaa caggtaatat tttagtttgc tcaggaccat tgagtattta tcgacgtgaa
      901 gtgattattc ccaacttaga gcgctataaa aatcaaacat tcctaggttt acctgttagc
      961 attggggatg atcgatgttt aacaaattat gctattgatt taggacgcac tgtctaccaa
     1021 tcaacagcta gatgtgatac tgatgtacct ttccaattaa aaagttattt aaagcaacaa
     1081 aatcgatgga ataaatcttt ttttagagaa tctattattt ctgttaaaaa aattctttct
     1141 aatcccatcg ttgccttatg gactattttc gaagtcgtta tgtttatgat gttgattgtc
     1201 gcaattggga atcttttgtt taatcaagct attcaattag accttattaa actttttgcc
     1261 tttttatcca tcatctttat cgttgcttta tgtcgtaatg ttcattatat ggtcaaacat
     1321 cctgctagtt ttttgttatc tcctctgtat ggaatattac acttgtttgt cttacagcct
     1381 ctaaaacttt attctttatg caccattaaa aatacggaat ggggaacacg taaaaaggtc
     1441 actattttta aataatatat gcatcgagta gttagagaag gagtaatttt atgaaaatag
     1501 cagttgctgg atcaggatat gttggattat cactaggagt tcttttatca cttcaaaacg
     1561 aagtcactat tgttgatatt cttccctcta aagttgataa gattaataat ggcttatcac
     1621 caattcaaga tgaatatatt gaatattact taaaaagtaa gcaattatct attaaagcaa
     1681 ctttagatag caaagcagct tataaagaag cggaactggt cattattgcc acacctacaa
     1741 attacaacag tagaattaat tattttgata cacagcatgt tgaaacagtt atcaaagagg
     1801 tactaagcgt taatagccat gcaactctta tcatcaaatc aacaattcca ataggtttca
     1861 ttactgaaat gagacagaaa ttccaaactg atcgtattat cttcagccct gaatttttaa
     1921 gagaatctaa agctttatat gacaacttat atccaagccg aattattgtt tcttgtgaag
     1981 aaaacgattc tccaaaagta aaggcagacg cagaaaaatt tgcactttta ttaaagtctg
     2041 cagctaaaaa aaataatgta ccagtactta ttatgggagc ttcagaagct gaagcagtaa
     2101 aactatttgc caatacttat ttagcgttaa gggtagctta ttttaatgag ttagacactt
     2161 acgcagaatc gagaaaatta aatagtcaca tgattattca aggaatttct tatgatgatc
     2221 gaataggaat gcattataat aacccatcat ttggttatgg aggttattgt ctacctaaag
     2281 atacgaagca attattggca aattacaata atattcccca aacgctaatt gaagctatcg
     2341 tttcatcaaa taatgtgcgc aagtcctata ttgctaagca aattatcaac gtcttagaag
     2401 agcgggagtc cccagtaaaa gtagtcgggg tttaccgttt aattatgaaa agtaactcag
     2461 ataattttag agaaagtgct atcaaagatg ttattgacat tcttaaaagt aaagacatta
     2521 agataattat ttatgagcca atgttaaaca aacttgaatc tgaagatcaa tctgtacttg
     2581 taaatgattt agagaatttc aagaaacaag caaatattat cgtaactaat cgctatgata
     2641 atgaattaca agatgttaaa aataaagttt acagtagaga tatttttaat agagactagc
     2701 catgtcttca tctataacaa taatattcat ttttacttta aaagaactgc agttggtggt
     2761 atgattgagc actatgaaat agtcgaaaaa tcatatgaaa acgtaacatg atgtcaaatg
     2821 aattccgttc tgaaaacgaa tgtcactaag ccatagatta taaaaagtga ggagttactg
     2881 atgaccaaag tcagaaaagc cattattcct gctgcaggtc taggaacacg ttttttacct
     2941 gctaccaaag ctcttgccaa agagatgttg cccatcgttg ataaaccaac catccagttt
     3001 atcgtcgaag aagcgctaaa atctggcatc gaggaaatcc ttgtggtgac cggaaaagct
     3061 aaacgctcta tcgaggacca ttttgattca aactttgaat tagaatacaa cctccaagct
     3121 aaggggaaaa atgaactgtt gaaattagtg gatgaaacca ctgccattaa ccttcatttt
     3181 atccgtcaaa gccacccaag aggactggga gatgctgtct tacaagccaa agcctttgtg
     3241 ggcaatgaac cctttgtggt catgcttgga gatgacttaa tggacattac aaatgcatcc
     3301 gctaaacctc tcaccaaaca actcatggag gactatgaca agacgcatgc atccactatc
     3361 gctgtgatga aagttcctca tgaagatgtg tctagctatg gggttatcgc tcctcaaggc
     3421 aaggctgtca agggccttta cagtgtagac acctttgttg aaaaaccaca accagaagat
     3481 gcgcctagtg atttggctat tattggtcgt tacctcctaa cccctgaaat ttttgatatt
     3541 ttggaaagac agacccctgg agcaggtaac gaagtgcaac tcacagatgc tatcgatacc
     3601 ctcaataaaa ctcagcgtgt ctttgcacga gaatttaaag gcaatcgtta cgatgttggg
     3661 gataaatttg gattcatgaa aacatctatc gactatgcct tagaacaccc acaggtcaaa
     3721 gaggacttga aaaattacat tatcaaacta ggaaaagctt tggaaaaaag taaagtacca
     3781 acacattcaa agtaatgtgt tggtacttta cttttttcct tgtttatagc aacttaagtt
     3841 tatatcttga aaattgtcaa cgttccaaaa tataaaagtt tt
//
LOCUS       DAUCXI010000084         3017 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.085, whole genome shotgun sequence.
ACCESSION   DAUCXI010000084 DAUCXI010000000
VERSION     DAUCXI010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3017
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.085"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(270..1142)
                     /locus_tag="VGY43_001749"
     CDS             complement(270..1142)
                     /locus_tag="VGY43_001749"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEQ4302896.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            1366..2676
                     /locus_tag="VGY43_001750"
     CDS             1366..2676
                     /locus_tag="VGY43_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEQ4302897.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLIAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPVLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISAQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            2754..>3017
                     /locus_tag="VGY43_001751"
     CDS             2754..>3017
                     /locus_tag="VGY43_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ4302898.1"
                     /translation="MPRKTFDKAFKLSAVKLILEEEQPVKMVSSTLKIHPNSLYRWIQ
                     EYEKYGESAFPGHGSALRHAQFEIKKLEKEHKLLQEELALLKKF"
BASE COUNT          883 a          691 c          532 g          911 t
ORIGIN      
        1 ctcctagtta acgactttga ttgattttat tatgatgaat cgtgatttct gaaaacaaaa
       61 ttttcttcat ggatttggcg tggaactttt acaataaaaa cactaacctc tccctatcgt
      121 tttttcaggt gaatgcttgg aattggtata ataagcgcac acgaatcagg tgaaaacagg
      181 gaaagtattt gaagaggcgt ttaaactatc tgacataaaa ctcattctag aggaaagaca
      241 tcctttaaaa agttagttta ttttgcaact tagacatcaa ggtaggttaa acccttcatg
      301 gaaaaatcga gactcttagc actatgggtt aaactaccac tggagacgta atcaatcgct
      361 aaaccacgaa aacggctaat agtggtcata tcaatatttc cagaacattc aatccgagaa
      421 cgtcctgcaa ttagagtaat ggcctgttca atctgttcca atgacatatt atccaacatg
      481 ataatatcaa cacccgccgc cgcagcttct tcggcagcag caaggctttc cacttccacc
      541 tcgaccattt tcacaaaagg ggcataggca cgcgcttgag caatcgcctt ttgaacacta
      601 cctactgccg caatgtgatt gtcttttagc atgatagcat ctgataaatt aaagcgatga
      661 ttatagccac cgccaactct cacggcatat ttctcaaaaa gacgtaaatt aggagtggtt
      721 tttcgagtat caaatacctt aatgcgatca tcgcctaagg cttctacata agcagctgtc
      781 atcgaagcaa tccctgataa atgttgtaaa aaattcaagg caacgcgttc acatgttaag
      841 aggcttctca ccgagcctat gatttctaaa accaaatcgc cactagtcaa acgatcccca
      901 tccttaaatt gatgaggatt ctggaaggtc acctcggcat caaatagggt aaaaaccctt
      961 tgaaaaacgg ttagccccgc taaaacacca gcttccttgg caaaaagcga caccttggct
     1021 tggccatgat gatcaaaaat ggcattggta ctgtaatctt cggaatgaac atcttctcgc
     1081 aaggctgctt tcaatgtatc atctatttga aaaggggtta aatcagttga aatgattgac
     1141 atcactaagt cctctatttt taatatcact tgtaagcact agaggcaatt gctattaact
     1201 tccgtaggaa atcacaaacc tgaatacctc attttaaatt ccaacaagtg tcaagtcaat
     1261 tgtaattttt ttgtgtataa tagtcaagta ccaataggaa acaggtggtc ttttgagcgc
     1321 caaaattgcc aacctatttt tatattctaa ctaaaggaca attcaatgat tcatttaata
     1381 ataattagcg ccattgctct agccattgga attggttacc gcaccaaaat caatattggc
     1441 ctgctggcta ttgctttttc ttacctcatc gcaaccactc tcatgggatt aagccccaaa
     1501 gaacttcttc atttttggcc aacctcactc ttttttacca tttttagtgt ctctctcttt
     1561 tataacgttg caacaactaa cggcactctt gatgttttgg ctcaacacat tctctaccgc
     1621 acacgcaccc accctaacgc cctctacatg attttatacc tgatagcaac ccttttgtct
     1681 gctttaggtg ctggattttt cactactatg gctgtttgct gtcctctagc gattaccctc
     1741 tgtcaaaaag cggacaagca ccctttgatt ggagctcaag ccgtcaattg gggagcttca
     1801 ggaggggcta atttgataac cagtggctca ggcattgtct ttcaaggcct gtttaagcaa
     1861 atgggatggg aagagcaagc tttttcactt ggcaatcata tctttatcgt tagcattatc
     1921 tacccactca tcgtcttgct tttattatct tgttacatcc gctacagtaa gggaagaaca
     1981 aactcatcct tgactattga ccaaccacca gtcctcagca aggtccaaag acaaaccacc
     2041 ttgctcatga tcagcagcat ggttttggtt tggctttttc ccttgttgca tctcattttc
     2101 ccaaacatcg catggatagc tacttatcga caaacatttg atattggctt tgtctcaata
     2161 ctcatggtct gcctcgcctt aaggctcaaa ttagggaagc aagaagccat tttggctaag
     2221 gttccctggg ctataattat tatgctctgc ggcatgagct tactaatgtc tctagcggtc
     2281 aagtcaggtt tagtcacact gatagggcac ctcataacaa caaccattcc tcatttctgg
     2341 ttacctctgt tcttttgtgt gatagccgga gtgatgtcac tctttagttc caccctatcc
     2401 gttgtagccc caactctctt tcccatcatt gctaccatca gtgctcaaag tcctcacatt
     2461 gatattcgct tactcacaac agccactatt attggcgctc tatctactaa tatctctcct
     2521 ttttcatcag ctggttccct cattcaactc tcccttcccc atatagagga acgcagtctt
     2581 gctttcaaaa aacaaattct tctgggtgtg cccatcagct taagtttggc actcttgacc
     2641 atctggattc tcatgctgct agcttcctta agttagattt attgtctaac ttaagtttgg
     2701 acttggtata ctaaagtaga cacaaaatta agtggaaacg aggaaaagtc attatgccaa
     2761 gaaaaacctt tgataaagcc ttcaaactct ctgctgtaaa actcatcctt gaggaagagc
     2821 agcctgtaaa aatggttagt tcaactttaa aaattcatcc caatagtctt tatcgatgga
     2881 ttcaagaata tgaaaaatat ggagaaagtg cgttcccagg acatgggagc gcacttcgtc
     2941 atgctcaatt tgagataaaa aaacttgaaa aagagcacaa actgctacag gaggaattag
     3001 ctcttctaaa aaagttc
//
LOCUS       DAUCXI010000085         2657 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.086, whole genome shotgun sequence.
ACCESSION   DAUCXI010000085 DAUCXI010000000
VERSION     DAUCXI010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2657
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.086"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(10..654)
                     /locus_tag="VGY43_001752"
                     /pseudo
     CDS             complement(10..654)
                     /locus_tag="VGY43_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014572037.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            939..1166
                     /locus_tag="VGY43_001753"
     CDS             939..1166
                     /locus_tag="VGY43_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEQ4302899.1"
                     /translation="MEIKKLETFHQMTIEKLAKVEGGKNNWQANVSGVIAAGSAGSPI
                     GFPVCGVACGYIGAKTAITLWAGVTGATGGF"
     gene            1179..1379
                     /locus_tag="VGY43_001754"
     CDS             1179..1379
                     /locus_tag="VGY43_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEQ4302900.1"
                     /translation="MTTMKELTINDMASISGGNTPGDAVIGGLGGLASGLKFCKLPHP
                     VLTGGCVVGFTVGGAYLGYTAN"
     gene            1918..2199
                     /locus_tag="VGY43_001755"
     CDS             1918..2199
                     /locus_tag="VGY43_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEQ4302901.1"
                     /translation="MKILDIIFNLSDRKMIFLENVEKLGGYIVPFTLIILSVAYNFRH
                     PYPIWAAVLGGISLIVIFIYFILIVYLYLRYRYLVWKKIPEIKINSTEL"
     gene            2393..2657
                     /locus_tag="VGY43_001756"
                     /pseudo
     CDS             2393..2657
                     /locus_tag="VGY43_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771275.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          854 a          376 c          522 g          905 t
ORIGIN      
        1 gtaagtattt tagtcttcga aaatacttac aagacatcgt tctaaggctt cttcatttgg
       61 aaaaaccacc ctccttcttg ctttgtcgct tgatttcttt attgagtgat tcaatcaagt
      121 ttgtagagta aatactagac caaatgtaat gtggaaattg atagaaagtt aggagatttt
      181 ccgttgtttc aagtgatgtc ataacctttt tgtaacgagg cttccactca gaaacaagtg
      241 gtgaccatac atgcgctcaa taatgtcact gatttcgcgt gtcgtaacgc cagtctgata
      301 gagtttgatc accatctctt ccaagtggtc atctcgtcta gcataagatg gtaataaaac
      361 tggtgaaaac tcgccgtttc gatctcttgg gatgattaaa ttgactaagc catactttgt
      421 ttcaaactga cgagaataag tcccattacg gctattacct gtgttgtaac cttctttttc
      481 ataaggttca taaccaagaa aagctgatag ttcaacttgc aagaggtcat tcatagctat
      541 ttctaaagag gagcgaaaga attcatcaat atcttgtttt tgtgctagga agttaagtaa
      601 ttctgtggta aactgagtca tgggaataaa tctctttcta gtgaagtgtc gcaactctac
      661 tatacaggat ttattccttt ttgtgtgttt acacaagata ttttacacta ccatcaaaaa
      721 tcttaaaagg tatttataaa agcatgaatg gtatcattta aacttcttaa ttaattaact
      781 attgtcacag cgtaagtgta gagaggataa aaagacattt catgatgaaa aacagccttt
      841 taagattttg aaaccatgat actgttcttt atgatattct gtactagtcg aggttgcaac
      901 gagacaaatt taagaattat gaaaagaagt tattcgatat ggagataaag aaactggaaa
      961 catttcacca aatgactata gaaaagcttg ccaaggttga gggtggtaag aataattggc
     1021 aggcaaatgt cagtggggtt atcgctgcag gtagtgctgg atctcctata ggttttccag
     1081 tttgtggtgt agcctgtggt tatattggag ctaaaacagc tattactctt tgggctggtg
     1141 taacaggagc tacaggcgga ttctagagga aagaaaggat gacaacaatg aaggaattaa
     1201 caattaatga catggctagt ataagtggag gaaacactcc aggagatgct gtaattggtg
     1261 gtcttggagg cttagcttct ggattgaaat tttgtaaact gccacatcca gtattgacag
     1321 gtggatgtgt tgtaggattt acagttggtg gagcatattt gggatataca gcaaattaaa
     1381 tgatctatac gatttttatt attatgaatg cgtctataat gtttttaatc attgttgatg
     1441 ccattcataa aaaaatgttg ataaatctat accatattta gtgtttttaa ttttcaatca
     1501 attatccctt tcagaaaaat cggtaaacat gttatctatc gtagctttgg tagcgtcatt
     1561 atttgttttt atcgataaaa gaaaatagtg attatgccaa taaatttaga tatcactctt
     1621 agctttttaa aatacaaaag agtgaaatta aaatgaaaaa gacttcaaaa atatggaagt
     1681 gctaaaaaaa tggtctggct atcataaatg gaggcggaaa agacggagca aatatctttt
     1741 tgacagggat ggcaggtgct gcgcagggag tgacagtttg tgctcagaca ggcgtattta
     1801 tcccttggca aggttatatt ttgtgtggag cagctggtgc tgctacaaat attatctggc
     1861 ctcactaaat atataaatga ctatctatca ctgatgtata agtagtagag gagtggtatg
     1921 aaaattttag atattatttt taacctatct gatagaaaga tgatatttct agaaaatgtt
     1981 gaaaagctgg gaggttacat tgtccctttt acccttatca tcttgagtgt agcctacaac
     2041 tttaggcacc cttatcctat ttgggctgct gtactaggag gtatatccct tattgtgatc
     2101 tttatttatt ttatacttat tgtttatcta tatttgcgtt atagatactt ggtgtggaaa
     2161 aaaataccag aaattaagat taattctact gagctataat gcaatcacat ttaaggggaa
     2221 aatggatgac ttatacaata tcagtactta tgatatttaa ctttagagac taaagagtta
     2281 aaagcaaaat gcgtattaaa aattggttaa aaaagttata actgtctctg ataacaggaa
     2341 taacaatttg ttcggttata tttgctaccg atagagtaga ggaggtgaag atatgcgtaa
     2401 tatattaaga tttttaggta ttgttattat ttctgtgcag tgattctatt tagtataggt
     2461 agtttctacg atttaccatt aatgaaaaat atacaactta tctgttggag ttttatcctt
     2521 gatttattcg tttttgtcta caaacaaaga caaacgacag aagtgctcac atggtatcaa
     2581 gttgttaagc aattttggtt atttattaag tgtactattc ttattcctac cttaattgct
     2641 tttattataa taatagg
//
LOCUS       DAUCXI010000086         2622 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.087, whole genome shotgun sequence.
ACCESSION   DAUCXI010000086 DAUCXI010000000
VERSION     DAUCXI010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2622
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.087"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            13..923
                     /locus_tag="VGY43_001757"
                     /pseudo
     CDS             13..923
                     /locus_tag="VGY43_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(993..2399)
                     /locus_tag="VGY43_001758"
     CDS             complement(993..2399)
                     /locus_tag="VGY43_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
                     /protein_id="HEQ4302902.1"
                     /translation="MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSLAKLP
                     QTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKRIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LVPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFSVVGLSGLDLNSFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
BASE COUNT          913 a          550 c          439 g          720 t
ORIGIN      
        1 aaagaggaaa atatgaatat ttcaagcttg gcttatttta ttgagattgt taattgtgac
       61 tttaacttaa ccaaagcagc ccaaaaaagt catatttcgc aacccgccct tagtagttat
      121 atcaagacta tcgaaaaaga agaaggagtc gttttattcc agcgtcaaaa agggcgtcta
      181 gttggactaa cctcagtcgg cgaacgcttt tttgaaaatg ctaaggtggt tatcgcatca
      241 catgagcaat taatggctga tttgcggagt gaatccaaaa aatacaaagg agaaatttca
      301 atcggtattc ctcaactcat ctctggcatt gttttttctg agctcattcc aaaactcatc
      361 gaagaaaatc ccgaagttaa atttcatatt gtagaaacgg gtgcttatga actgcaaaaa
      421 aactgtttct aaaagaagtc gattttgcga ttttattaac acccactaca ctagatgcta
      481 ctattgctga tatcgacatt ctcctaagag atcaactctg cctttatatg agtcacaaaa
      541 cctttcaaga gacgtttgat agtaatccta acatctctat caaagcatta catcgtcaaa
      601 acttagtaac ttttgataaa acctttatga ttaatcacca gcttaccacc ttatttgaag
      661 aagcaaatag tcttcctgta gtcaaatgtt attctgcctc gtgggatttt ttattaaatt
      721 gcacgcgcta ttcctcttac ctaacaatcc taccaaggcc tattactcat tttgctcata
      781 tggacggttt agtggaggtc caactgaccg aacatccaaa atgggaagtt gttctagcct
      841 ctctcaagca caataaaaca agccatttaa aacattatat caagcacacc atcttagatt
      901 atttcatgaa ccagcgcttc taattgcttg actcagacct taaaaaaaaa cgcctgaagg
      961 aaacaatccc aagcgtttca tatagttatt tcctaaaata caaataggta aatgatggca
     1021 atacctgtga ccaccaagac acaaggaata gtataagcca caatttgatt gaattttagt
     1081 ttgaagtttg agaggtaaga taaggcccaa aaaggaacta tcaagtttgt tgtggcatct
     1141 cctaattgat acgcctgcaa aatcttacct aggtcattac caacttcgat ggttgcaggg
     1201 acgatatagg gagcttcaat cacaaatttt gagcctcctg atggtaccgc aatattcagc
     1261 aaagccgagt aaagataagc aaagaccggc catgttgtcc catttgaaat agcgacaaag
     1321 aaatgggaaa tctctagtcc tagacctgta ctttgaatga ttccaaaaat accagcgtaa
     1381 aatggaaact gaagcaccaa gccccaagat gacatgaccc cgtctttgaa taaggaacca
     1441 taatattctg gtccttgttg accacaaaga agcaacccta agcctaaaaa taaaaagtta
     1501 aaactattga gatctagacc agacaagccc accaccgaaa aatgataaag gctatagcta
     1561 acaatggccc caccaacaag atacatcact aagcgagatg cgttcatctt ctcagcaggt
     1621 gtgtttcttg caataacaac atgtgaagcg gtatcaagac tatggtgata gatctcatca
     1681 tcaagttcca tgattttagt ttcatctttt gggtgcgcca ataaagcaaa gcaaagcggt
     1741 accagcatac acaccactaa aagactgata aatggaagat tcaaaactga ttctgtcaga
     1801 ggaacacttt caggaacaac ctgtttataa gcatctgcga cactatttcg caaataatct
     1861 ggagtagccg aataaagcac cgcagcacca gataaaccag aagtagctgg taaaaaggta
     1921 aaaaataaag tagcaacaaa caaaggtgta tgcaccttaa tccttttttg cctagcctga
     1981 acaagcaact ctttcccaaa cacaatggca accatcatac caagacccca gtgtaaaaag
     2041 ccaaagatag aacctactac aatagaaaaa ataaaaatct gagtcctggt ttgaggcagt
     2101 ttggcaaggg acttaaacat tttatgagca ggtggagaac tcgctacagc attccctgtc
     2161 gcaagtaaaa tagtcatctg catggcaaag gacaacagcc cccaaaaacc atttacccag
     2221 ccatagataa tcccgcccgt cttttccgta ccaataaagg gactatccgt catcaacaca
     2281 gacatagtaa cgactaaaaa ggttaaaata aaacagataa aaagcgattc tggcatccat
     2341 ttcataaagc catcaatata gcgatccata aacctttttt tggttttgat gttattcatg
     2401 ttgtcaattc ctttcacatt gtccacaagc acttttgttc ttttgatcag taacctatcg
     2461 ataatattaa taagcgtttc tttagttcat ttagttatca ataagtttaa acccacaaaa
     2521 aacacttttg ttcccttttt attatgacaa cgttttcata aacaaacaac tatgattttt
     2581 ttattgcttc cataaccctt atttatagca aaaagaatgg cg
//
LOCUS       DAUCXI010000087         2622 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.088, whole genome shotgun sequence.
ACCESSION   DAUCXI010000087 DAUCXI010000000
VERSION     DAUCXI010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2622
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.088"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            171..584
                     /gene="yaaA"
                     /locus_tag="VGY43_001759"
     CDS             171..584
                     /gene="yaaA"
                     /locus_tag="VGY43_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEQ4302903.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKRFLAETTVLFNGEDE
                     KRRGKKIRVGDKISLPDQDLIITIVEPSQEEKEQFAEEIAEKTRVAALVKQMNQANKK
                     TSSKHKNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            586..1692
                     /gene="recF"
                     /locus_tag="VGY43_001760"
     CDS             586..1692
                     /gene="recF"
                     /locus_tag="VGY43_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEQ4302904.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLASYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFA
                     SQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH"
     gene            complement(1748..2611)
                     /locus_tag="VGY43_001761"
     CDS             complement(1748..2611)
                     /locus_tag="VGY43_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEQ4302905.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWIFGILGGFIWSIGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPMQFVVGSLALLLLIVGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFDVLSVILPMAFGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAILLGVVKS"
BASE COUNT          932 a          503 c          435 g          752 t
ORIGIN      
        1 agaaaaatga taaacataag tacagctttt gttaaaacta attaacaaga acttcaaaac
       61 taaatagtta tttggacgag tatgatactt tataaatagc tcttattcag ctattattat
      121 ttatttctgt tttatgctat aatgacttga atgacaaaat ggagatgaca atgatataca
      181 aattatttac agaatttatc accctacaag cccttcttaa agaattagga attatccaaa
      241 gtggtggcgc tatcaagaga tttctcgctg aaacaaccgt tctatttaat ggtgaagatg
      301 agaaacgtcg aggcaaaaaa atcagagtag gggataagat ttctctacct gaccaagact
      361 taattatcac tattgttgag cctagtcaag aagaaaaaga acaatttgcc gaagaaatag
      421 ctgaaaagac acgtgtagcg gctctagtga aacaaatgaa ccaagctaac aaaaagactt
      481 cttctaaaca taaaaatcgt caatctacta ccaaaaaatc actaagagca actaagaaaa
      541 ctaaaggtaa accaactgca cctgtccgct tcccaggtat ctagtatgtg gattaaagag
      601 ttagagttaa aacattatcg caattatgac cacctgcttg cctcattttc gtcgggttta
      661 aatgtcttta tcggtaataa tgctcaagga aaaaccaatt ttctcgaggc aatctatttt
      721 ctatcactta ctagaagtca tcgcacgagg gctgataaag aattgattca ttttgatcac
      781 tcaactgttt ctcttactgg taagattcag cgtattagtg gtactgttga tttagaaatc
      841 aatctatcag ataaaggacg tgtaacaaag attaatgcgc taaagcaagc aaaattatct
      901 gattatattg gaacgatgat ggttgtgctt tttgcaccag aagatttgca actagttaag
      961 ggagcaccta gccttcgtcg caaatttatc gacattgacc ttggtcaaat taagcctgtt
     1021 tacttatctg agttatccca ttataaccac gtgcttaaac agcgtaatag ctatttaaaa
     1081 agtgcccaac aaattgatgc cgcttttcta gctgttctag atgagcaatt agctagctat
     1141 ggagcccgtg tcatggaaca tcgtattgat tttatcaatg cgttagagaa agaagcaaat
     1201 actcatcacc aagccatctc aaatggttta gaaagtctct ctctctccta tcagtcgtca
     1261 gttgtctttg acaaaaaaac taatatttac caacaatttt tacaccaact tgaaaaaaat
     1321 catcagaaag atttcttccg taaaaacact agcgttggcc cacatcgcga tgacttagcc
     1381 ttttacatta acgggatgaa tgctaacttt gctagtcaag gtcagcaccg cagccttatt
     1441 ctttccttaa aaatggctga agttagttta atgaaggcct tgactggaga taatcccatt
     1501 cttttactag acgatgtcat gagcgagcta gacaatacac gacaaacaaa gttacttgaa
     1561 acagtaatta aagaaaatgt tcaaaccttt atcacaacaa caagtttgga tcacctgtca
     1621 cagttgccag aaggtatccg tatttttcac gtgacaaaag gaaccgttca aattgattct
     1681 gatattcact aataacatca aaaaagggtt cagttaaact gagccttttt ttgatattat
     1741 gtggcgatta agatttgacc acacctaata aaatagcacc tacgataaaa caaataattc
     1801 ctgtgacaac ccaacgcatt tcttttttgg ttttggtttc gcctaggaat aaaatgcctc
     1861 cgacaatcga aatgatagca cctaattgtg agaaactaaa ggcaatagca agtcctgctt
     1921 ttgatgcagc taaaagcata aaaatattcc caatgcccca aagtaatcca acaacgctat
     1981 ttttaatcac atactggtca atggaaattt taaatgacat gaaagttata gctcctagga
     2041 ccataccaaa tgccattggt aaaataacag ataaaacatc aaatttcatg atgttattaa
     2101 ataagactgc atacatcacg taaccaattg ttgaataagt gagcgcccta aatccttttg
     2161 aaaaattatg aaggtgattg acttgtgcat tagcatcatc ttgtttacta gaaaagtaga
     2221 aaccaacaat cagaagtaat agtgctagac ttcctactac aaattgcatc ggttttgtcc
     2281 attcatgaaa aacgaggaca ccaatcaaac ttcccagaac aagttgagag ccacttgaca
     2341 aaggattggc aacggagact cccatgtatt gcatggcatg aaattgacca gtttgaccaa
     2401 ttgaccagat aaaaccgcct aaaatcccaa aaatccaaag ttgcagtgtc atctcaggtc
     2461 taacaattaa ccaaacagct aatgaaaata ataaagcccc aaaagtcatt cctagagttt
     2521 gttgcgaagg ttttcctcca attttgttac taacaaatcc aatgcttccc catgtaaaca
     2581 tgggaataag tgcataaaaa ataccttcca aaatgttatc tc
//
LOCUS       DAUCXI010000088         2522 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.089, whole genome shotgun sequence.
ACCESSION   DAUCXI010000088 DAUCXI010000000
VERSION     DAUCXI010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2522
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.089"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..591
                     /locus_tag="VGY43_001762"
     CDS             <1..591
                     /locus_tag="VGY43_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEQ4302906.1"
                     /translation="NILSLINPSESQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEE
                     NHNLTSYARLLSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKY
                     LTDYFIWSNGTNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPD
                     SPEVKAIQNDLKNIQYDVTIGKGYLLKHKTFFKISR"
     gene            770..1465
                     /locus_tag="VGY43_001763"
     CDS             770..1465
                     /locus_tag="VGY43_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEQ4302907.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            1467..1808
                     /locus_tag="VGY43_001764"
     CDS             1467..1808
                     /locus_tag="VGY43_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEQ4302908.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            1801..>2522
                     /locus_tag="VGY43_001765"
     CDS             1801..>2522
                     /locus_tag="VGY43_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEQ4302909.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVAVCIVSLVFIMYYDIGHSKKFQKLMFSELLSNISFQNSLKLLKESFP
                     LFLNGFLIIYIYTQPKYAIELMT"
BASE COUNT          843 a          366 c          425 g          888 t
ORIGIN      
        1 aatattttat ctttaattaa tcctagtgaa agccaatttt tttcagttat tacaatgcaa
       61 aatcatattc cttggtcatc cgattatcct gaagaaattg ttgctgaagg aaaaaatttc
      121 acggaagaag aaaatcacaa cctaacaagt tatgctcggt tattatcgtt tactgataag
      181 gaaacaagag catttttaga aaaattaaca caaattaaca agcctatcac agtggtgttt
      241 tacggagatc atttacccgg tttatatcct gatagtgctt ttaacaagca tattgaaaat
      301 aaatacctta ctgattattt tatttggagt aatggtacta acgagaaaaa aaatcatccg
      361 cttatcaact caagtgattt tactgcagct ttatttgagc atactgattc aaaagtatca
      421 ccttactatg ctttgttaac agaggtactg aataaagcta gtgtcgataa atcaccagat
      481 agtcctgaag ttaaagctat tcagaatgat ttaaaaaata tccaatacga tgtgactata
      541 ggaaaaggtt accttttgaa acacaaaact ttttttaaga tatcacgtta agaaaaatgc
      601 taggctgtcc gagtataggc aagcatcaag gtttggtaat ttgctcaaat gattgtcaac
      661 agagtgtcta ggaccaggtt taaaagatta taattcttaa ggtcttattc gtttataaaa
      721 aatgaatact cttttaaaat cttaattgaa atgaatagga gaagttttcg tgaaaaagtt
      781 aatcattatt cctgcttaca atgaaagcag taatattgtc aatactatac gtactattga
      841 atcagatgcc ccggattttg actatatcat tattgatgat tgctcaacgg ataatacgtt
      901 agcaatatgt caaaaacagg ggttcaatgt tatttctttg cccattaacc tgggaattgg
      961 cggtgcggtg caaactggct atcgttatgc acaaagatgt ggatatgacg ttgcagttca
     1021 agtagatgga gatggtcagc acaatccatg ctatttggaa aaaatggttg aggtattagt
     1081 tcaatcttca gtaaatatgg taattggatc acgatttatc acaaaagaag ggtttcagtc
     1141 atcatttgct cgacgtatcg gcataaagta ttttacttgg cttattgcgc tactaacagg
     1201 aaaaaaaata acagatgcaa cgtcaggtct aaggttaatt gaccgttcat tgattgaacg
     1261 ttttgctaat cattatccag atgattatcc tgaacctgaa acagttgttg atgtattggt
     1321 tagtcatttt aaagtgaaag aaattcctgt tgtaatgaat gagcgacaag gcggtgtgtc
     1381 atctatctcg ttgacgaaat cggtctatta tatgattaaa gtgactttag ctattttagt
     1441 tgttagattg aaaggaaatc gttaaaatga cggtaacagc cagtttattt ataagtttta
     1501 ttgtattaac ctttgttttc tttttgatta acttaatcaa aaaagataaa ctagcgatta
     1561 agtactcttt attgtggttt attttagctt tattaatttt actatttacg tggttaccta
     1621 acatattaaa taaaatgtct cacttcctgg gtattcattc accaaccaat atgttattct
     1681 ttttaggttt ttgtttgagt ttagctatta ttttttcact gactaataat atttcacttc
     1741 aaaatgataa agtaaaacgt ctgacccaag aagtggccct tatgaaaaaa gagaaaacca
     1801 atgattaatc cttcaaaaca aaaccaaacg atttttttat ggaatatgtt aggaagttta
     1861 tcaacagctg taatatcagt tatattactt atggtggtta ctaggttact aacttcggct
     1921 gattcagata tttacgcctt tgcctattct tttgctaata tgatggtagt tgttggactt
     1981 tttcaggttc gtaattatca agcaacagat attaatgaaa aatattcctt tagtcagtac
     2041 ttagtggcaa gactgatgac ttgtttatta atgttagcca taacagtaat ttatttaacg
     2101 ttaactaaga cagatagcta caagagtaca attgtctttc tagtctgttt ctatagatcg
     2161 acagatgctt tttcggattt atatcaggga atgttccaac aacatgaacg gctggatatt
     2221 gcaggtaaat cgctagccta cagaaatact cttattttta tggtgtacac agcaataata
     2281 ttatattcca aaaatcttac tttagcatta gtagctgtct gtatagtttc attagttttt
     2341 ataatgtatt atgacattgg tcattcgaaa aaatttcaaa agttgatgtt tagtgaatta
     2401 ttaagtaata tttcatttca aaacagttta aagttattaa aagaaagttt tccacttttt
     2461 ctaaacggtt ttttgattat ctatatttat actcaaccaa aatacgctat tgaactaatg
     2521 ac
//
LOCUS       DAUCXI010000089         2476 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.090, whole genome shotgun sequence.
ACCESSION   DAUCXI010000089 DAUCXI010000000
VERSION     DAUCXI010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2476
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.090"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..512
                     /locus_tag="VGY43_001766"
     CDS             <1..512
                     /locus_tag="VGY43_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEQ4302910.1"
                     /translation="LFRRDDKLWPGKIYTSNILDLDLNYLPTRMAWCYGMPGTAVALF
                     KMCQLIDLNFIDDINESLIAQMRSSDKNVYSLTMCHGLAGVTFIYDLIGKNYSSERLT
                     RFAEELRQQIITSFSTTKVFGYTDREKFGEIEVELESIGILQGVSGIVLFLLNPYSDE
                     ELLWQRIFI"
     gene            531..>2476
                     /locus_tag="VGY43_001767"
     CDS             531..>2476
                     /locus_tag="VGY43_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic dehydratase family protein"
                     /protein_id="HEQ4302911.1"
                     /translation="MYKVFPTGMIRIPLQKQEFYNKDYEDLINDKVFMEQLLVASPSL
                     YDSVIDFDKCNEKKKQNVKVSLNSYSKRAAFRTTPFGIFTAINTVDLTKGTTSNVQKV
                     SFIKKAVPDYSWIYSLVKSYEISNLEKLSLKINTAAFTQGDRYVLPFTVNESEEDRNI
                     SFSKPIKLLVEKCKTRYIKYEELIDVFKNNYPDIVSYMLESYIHDLVTNDFLISDLRP
                     PICNINSLDYLLSKLEEGTLCTDLTTLKKMIEDYNDLNIGEGRDLLLQIFDKMESIYK
                     YDNGGNYLKVDSLAEYEGDFNILSETARESIERLAEMFVKLNTNVKRRGGRKNSLEEY
                     QLKFIGKYGENCSIPFVEVINKDAGIGFPEYYKGGEGEAIELSDPIMQMFEKKYEEAL
                     LNGGHIEFYSKDLDDFQTDQSNSLDSFELNFNIKIINNDVKLYLGANIGSGQAGRSFG
                     RFYGLSETVRETIKNLNHQNNTNVELSFVPKQIRLANVIQNYSDESYNTSVFTTSWDS
                     ENELRLEDIYIRYSDGKFHFTTIDGENELKFTMNNMLNSDSQSRVLRLLVDLSEFEYG
                     LSHWSLFPWDILAQERVYIPEILFEDIPIATAQWNLSVIREEIIHQKIFTGKKDIFNK
                     FRKTYKIPKDIILKYADNELRLDLS"
BASE COUNT          931 a          280 c          465 g          800 t
ORIGIN      
        1 ttttatttag aagggatgac aaactatggc ctggaaaaat ttatactagt aatattttgg
       61 atcttgattt aaattatctt cctactagaa tggcatggtg ttacggtatg cctggaactg
      121 cagttgccct ttttaaaatg tgtcaattga tagatttaaa ttttattgac gatattaatg
      181 aaagtttaat tgctcagatg agaagttcag acaaaaatgt ctattctctt acaatgtgcc
      241 atggtttggc aggagtaact tttatatatg acttgattgg taaaaattat tcaagtgaga
      301 ggctaactcg ctttgcagaa gagcttcgcc aacaaataat tacatcgttt tcaactacaa
      361 aagtatttgg gtatactgac agagaaaaat ttggagaaat agaagttgaa ctggagtcaa
      421 tagggatatt gcaaggggta tcagggatag tgttattctt attaaatcct tacagtgacg
      481 aggagctatt gtggcaaaga atatttattt aatttgaaaa ggagaacaaa atgtataagg
      541 tatttccaac tggtatgatt cgtattccat tgcaaaaaca agaattttat aataaagact
      601 atgaagattt aataaatgat aaagttttta tggaacaact tttagttgct agtcccagtc
      661 tttatgatag tgtaatagat tttgataaat gtaatgaaaa gaaaaagcaa aatgtaaaag
      721 tctcattaaa tagttattct aaaagagcag cgtttagaac tactccattt ggtatcttta
      781 ctgctattaa tacagttgat ttgacaaagg gaaccacttc taatgtacaa aaggttagtt
      841 ttattaaaaa agcagtccca gattattcat ggatatattc tctagtaaaa tcgtatgaaa
      901 taagtaacct tgaaaaactt tcattaaaaa taaatacagc ggcgtttact caaggtgaca
      961 gatatgtact accatttaca gtgaatgaat cagaggaaga tagaaacata agtttttcaa
     1021 aaccaattaa gttacttgta gaaaaatgta aaactcgata tataaaatat gaagagttaa
     1081 tagatgtatt taaaaataat tatccagata tagtgtcata catgctagag tcatatatac
     1141 acgacttagt tacaaatgat tttttaattt cagatttaag accaccaatt tgtaatatca
     1201 attccttaga ttatctacta tctaaattag aagaaggaac actatgtact gacttaacta
     1261 ctttaaagaa gatgattgaa gattacaacg atttaaatat tggggaaggt agagacttac
     1321 ttttgcagat ttttgataaa atggaaagta tttataaata tgataacggt ggaaattact
     1381 taaaagttga ttcattagca gagtatgaag gcgattttaa tattctatct gaaacggctc
     1441 gggaaagtat agaacgactc gcagagatgt ttgtaaaatt aaatacaaat gtaaagagaa
     1501 gaggggggag gaaaaattca cttgaagagt atcagttgaa atttattggc aaatatggag
     1561 aaaactgctc aattcccttt gttgaagtaa taaataaaga tgcaggcata ggttttcctg
     1621 aatattacaa aggaggagaa ggtgaagcaa tagagttaag cgatccaata atgcaaatgt
     1681 ttgaaaagaa atatgaggaa gctctattaa atggagggca tatcgaattt tattcaaaag
     1741 atttagatga ttttcaaaca gatcaaagca atagtttaga ttcgtttgaa ttaaatttta
     1801 atataaaaat aataaataat gatgtgaagt tatatttagg agctaatatc ggttctggac
     1861 aagcaggtag aagctttgga agattctatg gattaagcga aacagtaaga gaaacaatta
     1921 agaatttaaa ccatcaaaat aatacgaatg tagagttgtc atttgttcct aaacagataa
     1981 gacttgcgaa tgtaattcaa aattatagtg atgagtctta taatacttca gtttttacca
     2041 catcatggga ttcagagaac gaactgcgat tggaggatat ttatataaga tatagtgatg
     2101 gtaagtttca ttttacaact atcgatgggg aaaatgagtt gaaatttacc atgaataata
     2161 tgctaaattc cgatagccaa agcagggttt tgagattgtt ggttgattta tctgagtttg
     2221 agtacggttt atcgcattgg tcattatttc cttgggatat tttggctcag gaaagagtat
     2281 atattcctga aattttattt gaagacattc cgattgccac tgctcagtgg aatttatcag
     2341 taattagaga agagattata catcaaaaaa tatttactgg taaaaaagat atattcaata
     2401 agtttagaaa gacttataag atacctaaag atattatttt gaaatatgca gataatgaat
     2461 tgaggttaga tttatc
//
LOCUS       DAUCXI010000090         2442 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.091, whole genome shotgun sequence.
ACCESSION   DAUCXI010000090 DAUCXI010000000
VERSION     DAUCXI010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2442
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.091"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..474
                     /locus_tag="VGY43_001768"
     CDS             <1..474
                     /locus_tag="VGY43_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA helicase"
                     /protein_id="HEQ4302912.1"
                     /translation="KLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAE
                     QIACVSSQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQS
                     LVQIAGRVGRSIDRPDGTLYFFHEGISKAMLLAKKEIKEMNYKGYSHDLSTMSTN"
     gene            446..1111
                     /locus_tag="VGY43_001769"
     CDS             446..1111
                     /locus_tag="VGY43_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEQ4302913.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVIYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            1191..1739
                     /gene="raiA"
                     /locus_tag="VGY43_001770"
     CDS             1191..1739
                     /gene="raiA"
                     /locus_tag="VGY43_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEQ4302914.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
BASE COUNT          924 a          373 c          417 g          728 t
ORIGIN      
        1 aaacttcctc ctaaaatttt aaaatactta aaaaaacaaa gaaaaacagg ctatcccctt
       61 ttaatttttc tacccactat tataatggca gaatctgtta cagcaatctt aaaagagtta
      121 ttgcccgccg aacaaatagc ttgtgtttct agtcaatcac aaaacaggaa agaagatatc
      181 acagcttttc gtcaagggaa aaaaacgatt ttaattacaa caacaatttt agaaaggggt
      241 gtgacatttc cccaaattga tgtttttgtt cttgggtctc atcatcgtgt ctatagttcc
      301 caaagtcttg ttcaaattgc tggacgagtt ggaagatcta tagacagacc agacggaacg
      361 ttatatttct ttcatgaagg tatcagtaaa gcaatgctac tagcaaaaaa agagattaaa
      421 gaaatgaatt ataaagggta ttcgcatgat ctgtctacta tgtcaacaaa ttagtcaaac
      481 accaataagt attacagaaa tcatcttttt aaggcgtatc tcttcaccga tttgtcaaca
      541 atgtcaaaaa agctttcaaa agataggaaa aagtgtttgt gcgacatgtt gtgcaaactc
      601 agatataata gcttgtcgag attgtctaaa atgggaaaac aaaggataca atgtaaatca
      661 tagaagctta tattgttata atgctgctat gaaagcatac ttcagtcaat ataagtttca
      721 aggagactat ttattaagaa aagtttttgc agtagaactt gccgatgtta tcaccaagta
      781 ctataaaggc tatatcccag tcccggttcc tgtaagtccc ggttgttttc gagaaagaca
      841 atttaatcaa gtgagcgcta ttcttgaggc agctaatgtt atctaccttt ctctttttga
      901 aaagctagat aatactcacc aatcttccag aacaaaaaaa gagagattat tagtagaaaa
      961 atcttatcga ctactaaaag tatcaaacat tcctgataaa atccttatag tagatgatat
     1021 ttatactact ggtagtacaa ttatcgctct tagaaaacaa ttggctaaag tagcaaatag
     1081 tgacattaaa agtttgtcaa ttgcacgtta aaacttgcaa attttcatga aagcagtata
     1141 atagtattaa agataaagta agcgcttcaa gcgcgagaaa gaggtatcct atgattaagt
     1201 tcagtattcg tggagaaaat atcgaagtga cagaagctat tcgcgattat gtagaatcaa
     1261 agcttactaa aatcgaaaaa tattttgcta aagaccaaga aatagatgca cgtgttaatt
     1321 taaaagttta tcgggagaga tcttcaaaag ttgaggtaac gatcccatta gattcagtaa
     1381 cccttcgtgc tgaagatgtt tcacaggata tgtacggctc tattgattta gttgttgata
     1441 agatcgaacg ccaaattaga aaaaataaaa ccaaaattgc taaaaaacat cgcgaaaagg
     1501 ttccaactgg tcaagtcttt acaactgagt ttgaagctga agaagtcgat gagataccag
     1561 aagtacaagt tgtacgtact aaaaatgtga cattaaaacc aatggatgtt gaagaagcgc
     1621 gtttacagat ggaactattg ggacatgatt tctttatcta cactgattct gaagatggtg
     1681 cgacaaacat tttataccgt cgcgaagatg gaaacctagg attaatagaa gctaaatagt
     1741 tcacaactaa aacctacagg gatgattata cgtattttaa aagtgggaaa aagctattca
     1801 tgtttagagg tgacatgatg aaaatgagat taagtgatag atacgacagt cattatacta
     1861 acaaaagtat ctattacagt tcctctttaa gtaaatctta cgtaaaattc gtttgaaaaa
     1921 aagattagtc ccaattctgg gctagaaatt ctcaaaaaat atgaaaaagc gcgttttcag
     1981 aatataaagc gcgttttttt ctttttccat ttaacaataa aaaaattcat gacgaacatg
     2041 gtatcataag agaattttta ctttttaaaa aaaggtcaaa gactttctga caccaaataa
     2101 aaatagaatt ttttctaact aaaaataata gcacaatctt tggcagcaat ctgaattgtt
     2161 tttccataaa agatttaagc acttacgttt gcttaaaata taggttatgt gacgtgcgtg
     2221 caagatcaga ttataacaaa atagttccaa ataagcctat cactgagaaa gcatcacaga
     2281 agggttaaac tttttttgta ttagcgtttt atcagtacaa cctaacactt atttttataa
     2341 aaaaataaaa aagctattga caatcttata caagataacg tatactaata aagctgttgt
     2401 aaatatggta aagcaataga tgctatcagg aaaaaatgtg aa
//
LOCUS       DAUCXI010000091         2105 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.092, whole genome shotgun sequence.
ACCESSION   DAUCXI010000091 DAUCXI010000000
VERSION     DAUCXI010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2105
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.092"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            79..1911
                     /gene="lepA"
                     /locus_tag="VGY43_001771"
     CDS             79..1911
                     /gene="lepA"
                     /locus_tag="VGY43_001771"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEQ4302915.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDTKK"
BASE COUNT          615 a          387 c          494 g          609 t
ORIGIN      
        1 aatccgtaag aaaagatagg caaatgccta ccttttttgt tataatagaa ggaaagacta
       61 aatgtatagg aaaatagaat gaacagtcaa gatttaaaaa aacgtcagga gaagattcgt
      121 aatttctcca ttatcgcaca tattgaccat ggcaaatcta ctctcgctga ccgcattttg
      181 gaaaagacag agacggtttc gtctcgtgaa atgcaggctc agttattgga ctccatggat
      241 ttggagcgtg agcgtgggat taccatcaag ttaaacgcca ttgagcttaa ttacacggct
      301 aaagatgggg aaacctacat tttccacctt attgataccc cagggcatgt ggactttact
      361 tatgaagtat cgcgttcgtt ggcagcttgt gagggagcga ttctagttgt ggatgcagcg
      421 cagggtattg aagcacagac ccttgccaat gtttacctag cccttgataa tgatttggaa
      481 attttaccgg ttatcaataa aattgatttg cctgctgctg accctgagag agtccgccat
      541 gaagtagaag atgtcattgg acttgatgct tctgaggctg ttctggcatc agccaaggct
      601 ggtattggga tcgaagagat tcttgagcaa attgttgaga aggttcctgc tcctacgggt
      661 gatgtggatg cgcctttaca ggccttgatt tttgactctg tgtatgatgc ttaccgaggc
      721 gttatcctgc aagttcggat tgtgaacggt attgtcaagc ctggcgataa aatccagatg
      781 atgtcgaatg gaaaaacttt tgatgttaca gaagttggca ttttcactcc taaggcagtt
      841 ggacgagatt tccttgcaac gggagatgtt ggttatgttg cggcttctat caaaacggta
      901 gcagataccc gtgtggggga tacggtgact ttagctaata accctgctaa ggaagccttg
      961 catggctaca agcagatgaa cccgatggtc tttgcaggga tttatccgat tgaatctaat
     1021 aaatacaatg acttgcgtga agcgcttgaa aaattacaac tgaacgatgc cagtttacag
     1081 tttgaacccg aaacgtcaca agcgcttggc tttggttttc gatgcggctt tttaggcttg
     1141 cttcacatgg atgtgattca agaacgtttg gaacgtgaat ttaacattga tttgatcatg
     1201 acagcaccgt ccgtggtgta tcacgttcac acaacagatg aggacatgat tgaagtgtct
     1261 aacccttcag aatttccaga cccaacccgg gtggctttta ttgaagagcc ttatgttaaa
     1321 gcgcaaatca tggtgccaca agagttcgta ggggctgtta tggaattatc gcagcgcaag
     1381 cgtggtgatt ttgtgaccat ggattacatt gatgataacc gtgtcaatgt gatttaccaa
     1441 atcccgctgg ctgaaattgt ctttgatttc tttgataaat tgaaatcctc aacgcgaggc
     1501 tatgcgagtt ttgattatga catgtcagaa taccgcaggt cacaattggt gaaaatggac
     1561 attcttttga acggtgataa ggtcgatgcg ctcagcttta ttgttcataa agaatttgct
     1621 tatgaacgcg ggaaaattat tgttgataaa ttgaaaaaaa tcattccacg tcaacagttt
     1681 gaagtgccga tccaagccgc tattggtcaa aaaattgttg cgcgttcaga catcaaggcc
     1741 cttcgtaaaa acgttttagc gaagtgttat ggcggtgacg tgtctcgtaa acgtaaattg
     1801 ctcgaaaaac aaaaggctgg taaaaaacgg atgaaggcta ttggttctgt cgaagtccct
     1861 caagaagcct tcttgagtgt tctttcaatg gatgacgata ccaagaaata accaagctta
     1921 accgcttagt cttcagagga gaactcttgt gggtctacat gaccaaaaaa ttgattatct
     1981 cataaaaaaa gaactttaca atctctttca gataacacta taatggtatt atagtgttat
     2041 ctcattatta ggtgagcctg catttaatct tattaaagag aaagaggaaa caaaaactgt
     2101 gaaca
//
LOCUS       DAUCXI010000092         1912 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.093, whole genome shotgun sequence.
ACCESSION   DAUCXI010000092 DAUCXI010000000
VERSION     DAUCXI010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.093"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..807
                     /locus_tag="VGY43_001772"
     CDS             <1..807
                     /locus_tag="VGY43_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEQ4302916.1"
                     /translation="QQLIEYDGNGNILVYGRLKYFKEGISLYYIGEYLAECLLIEHSD
                     TLLIHAAAVYNPLSGHSILLLGDKGAGKTTVAIRLCIEHGYHLIGNDQVIFGSNSGIL
                     LTYAGTSFFKIRRTAVLSDNLLFKLFSKFFNRSLQFNKASWDDKISIFPKELGIRTCN
                     FSTEISKIYYIKTDKKEKQIYHSIWSDSLASLYLNELLGRHISGQVACFQSDNGKYFS
                     TMPLINYEKNNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            862..1851
                     /locus_tag="VGY43_001773"
     CDS             862..1851
                     /locus_tag="VGY43_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEQ4302917.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGIDIFLTLTAILKSYKIKEIDLQSKIHKKSFEKIEKI
                     FLEVSQSFFETINDNSLNQDKLRLNINFESHSRQFIKSSDILSSNDIENLKLRALFLL
                     QEEKQYPHGLSEVEWDGILSNTINNIYRYSSEEHSLYLLPLYLLRVYNYLKYN"
BASE COUNT          707 a          222 c          342 g          641 t
ORIGIN      
        1 cagcaactta tagaatatga tggcaatgga aatattttag tttatggaag attaaagtat
       61 tttaaagaag gaatttcatt atactacatt ggagaatact tagctgaatg tctcttgatt
      121 gaacatagtg acaccttatt aattcacgca gcagcagttt ataatccttt atctggccat
      181 tcaattttac tattaggaga taaaggtgct ggaaaaacta cggttgcaat aaggctttgt
      241 atagaacatg ggtatcacct tattggtaat gaccaagtaa tatttggttc gaactctgga
      301 atactactaa cttatgcagg gacatctttc tttaaaataa gaaggacagc tgttttgtcg
      361 gacaatttac tgtttaaatt atttagcaaa ttttttaacc gttcattaca atttaataag
      421 gcaagttggg atgataaaat ttcaattttc ccaaaggagt tgggaatacg aacttgtaat
      481 ttttctactg aaatctcaaa aatttattat ataaagacag acaagaaaga aaagcaaatt
      541 tatcattcaa tttggagtga tagtttagca agtctatatc taaatgagct attgggaagg
      601 catatttctg gacaggttgc atgttttcaa tcagataatg gaaaatattt ttctacaatg
      661 cctttgataa attatgaaaa aaataatcgg gtacgagaac agatagtgaa gggtattttc
      721 gctaaacaaa aattatttaa aattacagca gctacgccag ctaagattgc agaagcgatt
      781 atagaaaatg ttaagaaaaa ctcatagtgt gtgtgaattt ggggattaat atgaagtatt
      841 gaaaaaggag taagagtaat tatgtttgtg ataggcattc caactttaaa tgaggcagat
      901 aatatcagta gattagttaa acaaattgat gagtatgctg taaatttagg gaaagaaatt
      961 attattatta attcggatag taaaagtaca gatggaactc cgcagatttt tttagaaacc
     1021 aaaacttata acaccaaagt ttcgatagta tcagaagcta aaggaaaagg ttataatgtg
     1081 agaaatattt tcgaatatgc aataaatcat gtgccgaatt tctccggttt aattttgatt
     1141 gatggagacg ttgtctcaat gaaaaaaatg tggttagaaa agatgtttat agcaattgaa
     1201 tctggaaatg atcttataat cccaaattat gctagaaaat cttttgaagg aaatgcgaca
     1261 aaccatttta tttatcccat gttagtgaaa tttttcaaac gtgatatgcc ttatcaatgc
     1321 atctctggtg attttggatt ttcaagagga ttgataaaag atttaacttt gaagtgtaat
     1381 tggcacaaat atacattagg ttacgggata gatatttttt taaccttaac agctatatta
     1441 aagtcataca aaattaagga aatcgattta caatcaaaga ttcataaaaa aagctttgag
     1501 aagattgaaa aaattttttt agaagtttca caaagtttct tcgaaactat taatgataat
     1561 tctttgaatc aagataagtt acgtttaaat ataaattttg aaagtcattc aagacagttt
     1621 attaagtcca gtgatatcct atccagcaat gatatcgaga atttaaagtt aagagcgttg
     1681 tttttattac aggaagaaaa acagtatcca catgggctgt cagaggtaga atgggacgga
     1741 attttgtcta atacaattaa caatatttat agatatagta gtgaggaaca ttcgttatat
     1801 ttattaccac tttatttatt gagagtatac aattatctaa agtacaacta agttttcaat
     1861 ttttattaat cttgagaaga agtgtgattg gtggaatata tttcaatatg tt
//
LOCUS       DAUCXI010000093         1830 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.094, whole genome shotgun sequence.
ACCESSION   DAUCXI010000093 DAUCXI010000000
VERSION     DAUCXI010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1830
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.094"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..512
                     /locus_tag="VGY43_001774"
     CDS             <1..512
                     /locus_tag="VGY43_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEQ4302918.1"
                     /translation="KFLNIKYVRIFGGIGCSVDDFLNNELFLNLLKETEIIFLIENEL
                     GTSVSTADDLLKIGHFIDEKSIKNLKIWFDIANYYIVEPQVDKVIPKLKKYIYYIHCK
                     NYVNNDLGIHYVELGKGIIDYKTIIHEIHEHFIDLIFSLEVHEKEIDKKAEVVRKSYL
                     TLNEYINGG"
     gene            514..1248
                     /locus_tag="VGY43_001775"
     CDS             514..1248
                     /locus_tag="VGY43_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEQ4302919.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSGFFIEDNDVLCIA
                     SKVVSVAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIRGLDYKWSENTSIKEALNE"
     gene            1241..>1830
                     /locus_tag="VGY43_001776"
     CDS             1241..>1830
                     /locus_tag="VGY43_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEQ4302920.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYTYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKMFASEQYFFSKILEKLLQVDCFSLDKIKEITVNFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKG"
BASE COUNT          690 a          213 c          359 g          568 t
ORIGIN      
        1 caaaattttt aaatatcaaa tatgtaagaa tatttggtgg gattgggtgc tcagtagatg
       61 acttcttgaa taatgaacta tttttgaatt tgttaaaaga gactgaaatt atctttttaa
      121 ttgagaacga gttaggaact tcagtgagca ctgcagacga tttgttaaaa ataggacatt
      181 ttatagatga aaaatctata aaaaatctaa aaatctggtt tgatattgca aattattaca
      241 tagttgaacc tcaggtagac aaggttattc caaaattgaa aaaatatatt tactatattc
      301 actgtaagaa ctatgttaac aatgatttag gaatacatta tgtagaacta ggtaaaggaa
      361 ttatcgatta taaaacaatc attcatgaaa tccatgaaca ttttatagac ttaattttta
      421 gtttagaagt acatgaaaaa gaaatagaca aaaaggcaga agtagtgagg aagtcttatc
      481 tgacactaaa tgagtatatt aatggaggct aaaatgaatt tgagtatatt tggtttaaag
      541 aatattcctt atttgaaaga aggggatagt atagaaaagc ttattgaaga aagcattaaa
      601 acttcaggat tttttatcga agataatgat gtgctttgca tagcttctaa agttgtatct
      661 gtcgcagaag gccaggtgat gtctttaaac gagatacaag tgagtgatgt agcaaaagaa
      721 atccacagga atattcctcg taaagatcct agaataattg aaattatgct aaatttagtc
      781 aatagagatc tgtcacgttt agatatcaaa aaaaattaca ttggttgtcg cttggaaaat
      841 ggtttaaagt tgacaagtgg tggaatcgat agaaaatcag tagatgaagt atttctttta
      901 cctaataatc cggatgcttc tgcaaaaaga atttcggaat atcttaaaaa atcacttgga
      961 aaaaatgttg cagttgttat aacagatagt gatggtagag aggataaaag aggtgctact
     1021 caagtagcaa ttggtattta tggtattcat cctttgagaa aaacagaagt aatagattca
     1081 caaggagaga caataaaatt ccaagaagag actttgtgtg atatgattgc agcttgtgct
     1141 ggcttagtaa tggggcaacg tggaactgga attccagctg tcctcattag gggcttggat
     1201 tataaatggt ctgaaaatac tagtattaag gaagcgttaa atgagtagaa atcaggactg
     1261 taagaatatt ctaatcattg gttttggaaa aattgggaaa attaaagcgt acaagtggct
     1321 atcacgcgga tatgaggtat atgtcaaaga tttgaaattc tccagcatga aataccttaa
     1381 tacaaatagt gatgtgttgg atgatttatc acgacaatat tttactattg agatttgtac
     1441 tccgacaaat caccacctta cgctattgaa aaccgttata acaaggtatg tctatactta
     1501 tattagcatt gaaaaaccac tgtgtaacag gttagaagat ttagaagaaa tgaagtcgct
     1561 agtagaaagt cacccacatc tagcaaaaaa aatgtttgcc agtgaacaat acttcttttc
     1621 gaaaattttg gaaaaactgt tacaagtaga ttgtttctct ctagataaaa tcaaggaaat
     1681 aacagttaat ttttctaaag ataggattga ggataacgag aatgggagat ttttagataa
     1741 agagatattg ggctatggaa tagagattcc tcatatcatt gctgtcattt cttatttagg
     1801 aatttcatta gaagaattca aaaaaggaat
//
LOCUS       DAUCXI010000094         1661 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.095, whole genome shotgun sequence.
ACCESSION   DAUCXI010000094 DAUCXI010000000
VERSION     DAUCXI010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1661
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.095"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..671)
                     /locus_tag="VGY43_001777"
     CDS             complement(<1..671)
                     /locus_tag="VGY43_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEQ4302921.1"
                     /translation="MTPQIKQIVDYIADSFINYEQIVAESENKVLINIESKYRNTFFD
                     KSLSHGVPSLILMYSSLYKVTKDERYLTFSNIYVEKLVDIISRDGIESPSLYAGTAGI
                     ALAIKEASISGKYYPKLLSSLNCLLKEQIKDKLVVSFSNIEKGIIEPYDYDMVNGFSG
                     ITNYLLLEQEFFSVELNQIGNYLLKYIETILNKVTNCSEDREAEFDLGIAHGITGPML
                     ILAKL"
     gene            complement(655..>1661)
                     /locus_tag="VGY43_001778"
     CDS             complement(655..>1661)
                     /locus_tag="VGY43_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEQ4302922.1"
                     /translation="QSIIMFLAVREAFLGILLVGNVTTFIRSLSTMQTSTQNIVNNIY
                     SFYNGSLYMELLYDFTHDELVHNPIIESTVDTIQSVEFERVSFSYNGKDNVINDISFS
                     IKAGERLAIVGENGSRKSTIFKLACGLYDNYEGNIYINGINLRSIQKKSYYKRISALF
                     QDFLKYELTLRENVGLGELSKLYSDEDLISALKYTGVDSIFYFNQEKLNQIDLEQQLG
                     NWFEDGRQLSGGQWQKIALSRVYLKEADCYLLDEPSSALDPESETKIFKTFFELSQNK
                     IGIFITHKPSITQSVNKILYLDNGCISETGSFADLNIKGMKFKNLLDKEIGATYDTSN
                     "
BASE COUNT          557 a          297 c          195 g          612 t
ORIGIN      
        1 tttaattttg ctaggattag cataggacca gtaattccat gtgcaattcc tagatcaaat
       61 tcagcttctc tatcttcaga acaattagtt accttattta aaattgtctc aatatatttc
      121 aaaagataat ttccaatttg atttaactct acagaaaaaa attcttgttc aaggagtaag
      181 taattagtta ttccactaaa tccgttaacc atatcataat catatggctc aataattcct
      241 ttctcaatat tagaaaaact tactaccaat ttgtctttaa tttgttcttt tagaagacaa
      301 tttaaggatg ataataattt cggataatac tttccagata tactcgcttc tttaatagct
      361 aatgcaatac ctgcagtgcc agcatagaga gacggagatt ctataccatc tctagagatt
      421 atgtctacta atttctcaac gtatatgttg gagaatgtta gatatctctc atcttttgtc
      481 actttatata gtgaactata cattaagatt aatgatggca caccatgact cagagattta
      541 tcaaaaaagg tatttctata tttagattca atattaatta gtactttatt ctcactttca
      601 gctactatct gttcataatt tataaaacta tctgcaatgt aatctactat ctgtttaatt
      661 tgaggtgtca tatgtggctc caatttcttt atctaataag tttttaaact tcattccttt
      721 aatatttaaa tcagcgaaac ttcctgtttc agatatacat ccattatcta gatacaaaat
      781 tttattcaca gattgagtaa tgcttggctt atgcgtaata aaaataccaa ttttattttg
      841 cgataattca aaaaatgttt taaaaatttt tgtttcagac tcaggatcta acgcagaact
      901 aggctcatct agcaaatagc aatccgcttc tttgagatat actcttgata atgcaatttt
      961 ttgccactgt ccaccagata actgtctccc atcctcaaac caattcccta attgctgttc
     1021 cagatctatc tgatttaatt tttcctgatt aaagtaaaat atcgaatcaa ctcctgtata
     1081 cttcagtgca cttattaaat cctcatcact atataacttt gataattcac ccaatccaac
     1141 attttcacgc agtgtcaatt catactttaa aaaatcttgg aacaatgcgg atattctctt
     1201 gtagtatgac tttttctgta ttgaacgaag attaatacca tttatatata tattgccttc
     1261 ataattatcg taaagaccgc aggctaattt gaaaatcgta ctttttctag aaccattttc
     1321 accaacaatt gctaacctct ctcctgcttt aattgaaaaa cttatatcgt ttattacatt
     1381 atccttacca ttatatgaaa aagaaactct ttcaaattca actgactgaa ttgtatcaac
     1441 cgtactttcg attatagggt tatgtactaa ctcatcatgc gtaaaatcat acaataactc
     1501 catgtacaat gaaccattat agaaagaata gatattattt actatatttt gtgtacttgt
     1561 ttgcattgta gataaagacc ttataaaagt agttacattt ccaactaata atattcctag
     1621 aaatgcttct ctaactgcaa ggaacataat aatagattgt a
//
LOCUS       DAUCXI010000095         1628 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.096, whole genome shotgun sequence.
ACCESSION   DAUCXI010000095 DAUCXI010000000
VERSION     DAUCXI010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1628
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.096"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..473
                     /locus_tag="VGY43_001779"
     CDS             <1..473
                     /locus_tag="VGY43_001779"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEQ4302923.1"
                     /translation="GIELPHILAILRYLGISSDEFVNGVFVNNLYIKDLRNHDYSIEI
                     LSRIRNISIEINSNLGSFSIKDGKQMNRKNGTVRTARIDDSILIFDPHPKIERYRSEL
                     INGDNKIQISDDMIDKQLTLLEENRIPRGCDIISAIEITKVLLKLYLECNKIYV"
     gene            485..>1628
                     /locus_tag="VGY43_001780"
     CDS             485..>1628
                     /locus_tag="VGY43_001780"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEQ4302924.1"
                     /translation="MELKITNDFYSPSQLAYEVVERKGLGHPDTLADGIAEQIEIDYS
                     QYCLNRFGIIPHHNFDKIIIRGGHSIQNFGGSDFIEPIKIIFLGRASKKCFDIPIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKSNWFSPTTIEDLPEYKDVPKAN
                     DTATMISYWPLTISEELALMIEGYFYKLDINKLPTPRFIQMGGDIKVMVVRNDLHYSI
                     RINFPLISKFFNNEIESRLYVDKHVEKIKEYVEQKYKRLNYSIDYNYYLTSTGSCIDF
                     GEEGAVGRGNKTHGIISSFRPNTMEAPAGKNCTYFVGKVWGFLSDIIAKDIYETFKTP
                     CQVIMQSNIGSELYKPTHLYIQTEESIDQTRVLEIINRHLCKGSKNT"
BASE COUNT          623 a          186 c          283 g          536 t
ORIGIN      
        1 acggaatcga acttccgcat atattagcga ttttaagata tttaggaata tcatcagatg
       61 aatttgttaa tggtgttttt gtaaataatc tttatataaa agatttaaga aaccatgatt
      121 attcgataga aattttatct agaattagaa atatatcgat agaaattaac agtaatttag
      181 ggagtttttc gataaaagat ggaaagcaga tgaatcggaa aaatggaaca gtaagaactg
      241 ctagaattga tgactcaatt ctgatttttg atccacatcc taagattgaa agatatagaa
      301 gtgagttaat taatggtgat aataaaattc aaatttctga tgatatgata gataaacaat
      361 taacattatt agaagagaat aggataccaa gagggtgtga tattattagt gctattgaaa
      421 taacaaaagt gttacttaaa ttatatttag aatgcaataa aatttatgta tagaggtata
      481 aattatggaa ttaaaaatta ctaatgattt ttatagtcca agtcaattag catatgaggt
      541 tgtagaacgt aaaggattag gtcatcctga taccttagct gatgggatag cagagcaaat
      601 tgaaattgat tattctcagt actgtttgaa tagatttggc attattccac atcataattt
      661 tgataaaatc attataagag gtggacattc cattcagaat tttggtggta gtgactttat
      721 tgaaccaatt aaaattattt ttttaggtag ggcgagcaaa aaatgttttg atattccaat
      781 tccacttttt aaaattcaaa aaaaagctgc aactaaatat ttaaatagaa ttctccccaa
      841 cttagatgtt gaaaattacg tagaattcga aacattgact tcagatttta ctacaaaatc
      901 taattggttc tcccctacta caatagaaga cttaccagag tataaagatg taccaaaggc
      961 aaatgataca gctacaatga taagttattg gcccttaaca atttcggaag aattagcctt
     1021 aatgattgaa gggtattttt ataaactaga tatcaataaa ttgccaacgc cacgatttat
     1081 tcaaatgggt ggagatatta aagtgatggt tgtaaggaac gatttacatt attctattag
     1141 aataaatttt cccttaataa gtaaattttt taacaacgag attgaaagta ggctatatgt
     1201 tgataaacat gtagaaaaaa ttaaggagta tgttgaacaa aagtataaaa ggctaaacta
     1261 ttctattgat tataattact atttaacttc tacaggttct tgtattgatt ttggagaaga
     1321 aggtgccgtt ggtcgaggga ataaaactca tggtatcata tcaagcttta gaccaaatac
     1381 tatggaagca ccagcaggta aaaattgtac ttattttgta gggaaagttt ggggattttt
     1441 atctgatatt attgctaaag atatttatga aacgtttaag actccatgcc aagtaattat
     1501 gcagtcaaat attggttcag aactgtataa accaacccat ttatatattc aaacagaaga
     1561 aagtattgat caaacaaggg tattggaaat tattaatagg catttatgta aaggttcaaa
     1621 aaatacga
//
LOCUS       DAUCXI010000096         1548 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.097, whole genome shotgun sequence.
ACCESSION   DAUCXI010000096 DAUCXI010000000
VERSION     DAUCXI010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1548
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.097"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            20..940
                     /locus_tag="VGY43_001781"
     CDS             20..940
                     /locus_tag="VGY43_001781"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEQ4302925.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNKKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            994..1242
                     /locus_tag="VGY43_001782"
     CDS             994..1242
                     /locus_tag="VGY43_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEQ4302926.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(1367..>1548)
                     /locus_tag="VGY43_001783"
     CDS             complement(1367..>1548)
                     /locus_tag="VGY43_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEQ4302927.1"
                     /translation="DEEKKKIFDRFYRVDKARTRQTGGFGLGLALAQQIVMSLKGNIT
                     VKDNDPKGSIFEVKL"
BASE COUNT          544 a          291 c          223 g          490 t
ORIGIN      
        1 caaatgatta ggagctacca tgtcaaatga atttatcaac tttgaaaaaa tttctagaga
       61 gtcttggaaa acattacatc aaaaagcaaa agctcttctc acacaagagg aacttaaaag
      121 tattactagc ttaaatgata acatcagtat taacgatgtc attgatatct accttccatt
      181 aattaatctg atccaggttt acaaaattgc gcaagaaaat ctttcttttt ctaaaagcct
      241 ttttctaaaa aaagacattc aattaaggcc ttttattatt ggaatttctg gttcagtagc
      301 tgttggtaaa tcaacaacta gtcgtctttt acaactttta ttatcgcgaa cgcaccccaa
      361 tagtcaagtc gaactggtaa cgactgatgg ttttttatat cctaatcagt ttcttattga
      421 acaaggactg ttaaatcgta aaggatttcc agaatcttat aacatggaac ttctcttaga
      481 ttttctagat tccatcaaaa atggtcaaac tgcttttgca cccgtctatt ctcatgatat
      541 ttacgatatt atcccaaata aaaaacaatc atttaataac cctgacttcc ttatcgtcga
      601 aggtattaat gtttttcaaa atcaacaaaa caatcgttta tatatgagtg attactttga
      661 tttttctatt tatattgatg cagacagcag tcacatcgaa acctggtaca ttgaacggtt
      721 tctaagcatt ttaaaattag caaaacgtga ccctcataat tattatgccc aatatgcaca
      781 attacctcga tctgaggcta tagcatttgc gcgcaacgtt tggaaaaccg ttaatttaga
      841 aaatcttgaa aaattcattg aacctacacg taaccgtgct gaattaattt tacataaaag
      901 tgctgatcat aaaattgatg aaatttacct caaaaagtga taaagggttg ccaaacgcat
      961 atattttcta tataataatg tagttagatt aatttggagg tgaaaacatt ggcaaatatt
     1021 aaatcagcta ttaaacgcgc tgaacttaac gttaaagcaa acgaaaaaaa ctcagcacaa
     1081 aaatcagcta tgcgtactgc tatcaaagca tttgaagcta acccatctga agagcttttc
     1141 cgcgctgctt cttcaagcat cgataaagct gaatcaaaag gtttgattca caaaaacaaa
     1201 gcaagccgcg ataaagcacg ccttgctgca aaacttggct aataaatatc caatgaaaac
     1261 tccaactgga gtttttttat acggtaaaaa ctcaaaaaat acaataaagc gttgacagtt
     1321 aaaaataact ttaaaagggc tgaccttatt ggtcgccctt tttagcttat agtttgactt
     1381 caaaaatact acctttagga tcattatcct ttactgtaat atttcctttt aaagacatca
     1441 cgatttgctg agctaaagcc aaccccaagc caaatccacc tgtttgccgt gttctagctt
     1501 tgtcaactcg ataaaaacga tcaaaaatct ttttcttttc ttcatctg
//
LOCUS       DAUCXI010000097         1547 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.098, whole genome shotgun sequence.
ACCESSION   DAUCXI010000097 DAUCXI010000000
VERSION     DAUCXI010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1547
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.098"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..355
                     /locus_tag="VGY43_001784"
     CDS             <1..355
                     /locus_tag="VGY43_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEQ4302928.1"
                     /translation="YSIEILSCINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTID
                     DKTILFDPHPKLERYKSELVTGTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEIT
                     KLLINLYSECEKIYL"
     gene            365..>1547
                     /locus_tag="VGY43_001785"
     CDS             365..>1547
                     /locus_tag="VGY43_001785"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEQ4302929.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKAN
                     DTATMISYWPLTISEELALMIEGYFYKLDKNELPTPRFTKMGGDIKVMVVRNDLEYSI
                     RINFPLISKFFNNDIESQLYVDKHVEKIKKYIEQKYKNISFSIDYHYYLTTTGSCIDF
                     GEEGAVGRGNKTHGIISSFRPNTMEAPAGKNCTYFVGKVWGFLSDTIAKEIYEAFNTP
                     CQIIMQLNIGSKLYRPTHLFIQTEESVDQERVLEIVNRHLNNGKQNTNLILSTQHFIP
                     KT"
BASE COUNT          581 a          190 c          272 g          504 t
ORIGIN      
        1 ttattcaata gaaatattat cttgtattaa tcaaacagtg attaaaatta ttagtaattt
       61 gggaagtttt gcaataagag agggcaagat tgaaggaggt gatgctaaaa cagtaagaag
      121 agttaccatt gatgacaaaa caatactatt tgatccacat cctaaactcg agaggtataa
      181 gagtgaattg gtgactggga caaatacgtt tcaaatacac gatgatatga tggacacgta
      241 tatcagtttg ttagaaggaa atgctattcc tgaagattgc tatatcaata atgcaattga
      301 gataacaaaa ttattaatta acttatattc agaatgtgaa aaaatttatt tatgaggtgt
      361 aactatggat ttaaaaatta caaacggctt ttatgaccca agtcatttat catacgaagt
      421 agtagaacgc aaaggcttag gtcaccctga taccttagca gatggaattg ctgagcaaat
      481 tgaaattgat tactcacttt attgtttgga caagtttggt gttattccac atcataattt
      541 tgataagatt attatccgag ggggacattc agttcaggat tttggtggaa gtgactttat
      601 tgaaccaatt aaaattattt ttctaggtag ggcgagcaaa aaatgtttta atagttcaat
      661 tccacttttt aaaattcaga aaaaggctgc aactaaatat ttaaatagaa ttttacctaa
      721 tttagatgtt gaaaattatg tagaatttga gacattgacc tcagatttta ctacaaaaac
      781 taattggttc tcgcctgaag caatagaaga tttaccggag tatctagatg taccaaaggc
      841 aaatgataca gctacaatga taagttattg gccattaaca atttctgaag aattagcatt
      901 aatgattgaa gggtattttt ataaattaga taagaatgaa ttaccaacgc caagatttac
      961 taaaatgggt ggtgatatta aagtaatggt cgtaaggaac gatttagaat attctattag
     1021 aataaatttt cctttaataa gtaaattttt taacaatgat attgaaagtc agttgtatgt
     1081 tgataaacac gtagaaaaaa ttaagaaata tattgaacaa aagtataaaa acataagctt
     1141 ttctattgat taccattatt atttaactac tacaggttct tgtattgatt tcggagaaga
     1201 aggtgcagtt ggtcgaggta ataaaactca tggtatcata tcaagtttta ggccaaatac
     1261 tatggaagca ccagctggaa aaaattgtac ttattttgta ggaaaggttt ggggattttt
     1321 gtctgatact attgccaaag aaatttatga agcattcaat actccctgtc aaatcattat
     1381 gcaattaaat attggatcaa aattgtatag accaacccat ttatttattc agacagaaga
     1441 aagtgttgat caagaaagag tattagaaat tgttaacagg catttaaata atggtaaaca
     1501 aaatactaat ttaatcttgt caactcaaca ttttattcct aagacca
//
LOCUS       DAUCXI010000098         1537 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.099, whole genome shotgun sequence.
ACCESSION   DAUCXI010000098 DAUCXI010000000
VERSION     DAUCXI010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1537
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.099"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            119..1327
                     /locus_tag="VGY43_001786"
     CDS             119..1327
                     /locus_tag="VGY43_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEQ4302930.1"
                     /translation="MNNMKKNILYLVYSKGISRIGDVMFDYANNRFLAGINPTSLSLV
                     AIYQSLESVIGVLFNLFGGVIADSFNRKKIIIATNILCGLSCITLSFISQEQWLVYAI
                     VITNVILAFMSAFSGPSYKAFTKEIVKKDSISQLNSLLETTSTVIKVTIPMIAIFLYK
                     LLGIHGVLLLDGLSFLIATSLIFFITPVNEEVETKENMTIRGIFDDLKIGFTYVYSHK
                     QILIIIALSALVNFFLAAYNLLLPYSNQMFGSISSGLYGTFLTAEAIGGFIGAILSGF
                     INKSLSSKRLMLFLAYSGLMLMLVAPLYYMFRNVIILAFSPALFSLFLSIFNIQFFSI
                     VQRDVDNEFLGRVFGIIFTVAILFMPLGTVFFSVVLNPNNTFNLFIIGVSITILSLIF
                     STLLKRYDRN"
BASE COUNT          493 a          210 c          250 g          584 t
ORIGIN      
        1 tttacacgag atatttttca atatgattaa caaaaagatt gatatttgaa caaagtattt
       61 tttatttaat aatttcagtt aatagttgtc gtacccgaga attttaaagg tctataaaat
      121 gaataatatg aaaaaaaata ttctatactt ggtgtatagt aaaggtatat ctcgaatagg
      181 agatgttatg tttgactacg ctaataacag atttcttgca gggatcaatc caacgtcact
      241 atcgttggtt gctatctatc aatcattaga aagtgtgata ggagttctat ttaatttatt
      301 cggtggagtc attgcagata gcttcaatcg gaaaaaaatt attattgcta caaacatctt
      361 atgtggtctt tcttgcataa ctctttcatt tatatcccaa gaacaatggt tggtttatgc
      421 gatagtcata acaaatgtca ttttggcttt tatgagtgct ttttcagggc catcatacaa
      481 agcttttacg aaagaaattg taaaaaagga cagtatatca caacttaatt cattgttaga
      541 aacaacaagt actgtgatta aagtaacaat tcctatgatt gcaattttct tatataagtt
      601 acttggaata catggtgtgt tattattaga tggattatcg tttttaattg ctacctcact
      661 aattttcttc attactcctg taaatgagga ggtggagaca aaagagaata tgacgataag
      721 aggaatcttt gatgatttaa aaataggatt tacgtatgta tatagtcata aacaaattct
      781 tattataatt gccctttcag cacttgttaa cttttttcta gcagcctata atttgttgct
      841 gccatacagt aatcaaatgt ttggaagtat ttcaagtggg ctatatggaa cctttttaac
      901 agccgaagcg attggtggct ttattggtgc gatattaagt ggatttatca ataaatcctt
      961 gtcaagcaaa cgtttaatgc tctttttagc atattcaggt ttgatgttaa tgctagtagc
     1021 gccgctctat tatatgttcc gcaacgtcat tattttagcc ttttctccag cattatttag
     1081 tctatttctt tccattttta atatccaatt tttctctatt gttcaaagag acgtagataa
     1141 tgagtttctt ggcagagtat ttggaatcat ctttacggta gctattcttt ttatgccact
     1201 aggtactgtt tttttctcag tagttttaaa tcctaacaat acttttaatc tttttattat
     1261 tggtgtatct attacgatat tatcgctaat attcagcacg ctattgaaga ggtatgatag
     1321 aaattgatag atgataaaaa tatctgatat agagaattta gagcgccttt ggaatttaat
     1381 caatcacagt tgaatgtgaa gggcaatctg ttttataaga atacaatcaa gatatcatta
     1441 tgctattttt ttagttcagt taaaatattg agaagtatta cttttattta aaaagcatca
     1501 taaaggactc caattaatta ctaatgattt ttctaat
//
LOCUS       DAUCXI010000099         1477 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.100, whole genome shotgun sequence.
ACCESSION   DAUCXI010000099 DAUCXI010000000
VERSION     DAUCXI010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1477
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.100"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            52..1311
                     /locus_tag="VGY43_001787"
     CDS             52..1311
                     /locus_tag="VGY43_001787"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEQ4302931.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLIAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
BASE COUNT          445 a          236 c          340 g          456 t
ORIGIN      
        1 tttatgataa aatgaaaagg ttgaattcta gtataagaaa gttttgaatg tatgcgtaaa
       61 attattatta atggcggaaa agccttatct ggagaagtgg cagtttcagg ggcaaaaaac
      121 agtgttgttg cgcttattcc agcaatcatc ttagccgatg atattgtgat tcttgatggt
      181 gtacctgcta ttagtgatgt agatagtctg attgaaatca tggagcttat gggagcaaca
      241 gtaaactatc atggtgatac tttagaaatt gaccctagag gggtgcaaga catcccgatg
      301 ccttacggaa agattaatag tcttcgagct tcctattatt tctacggtag tcttttaggt
      361 cgttttggac aagcagttgt tggcttacct ggtggttgcg atttaggacc aagaccaatt
      421 gacttgcatt tgaaggcctt cgaggctatg ggagttgaag tgtcttatga gggtgaaaat
      481 atgaatttat cgacaaatgg tcaaaaaatt catggcgctc atatctatat ggacaccgtt
      541 agtgtcggtg ctacaattaa tactatggtt gcggcaacaa aagctcaagg taaaacggtt
      601 attgaaaacg ctgcacgtga gccagagatt attgatgtgg ctactctttt gaataacatg
      661 ggtgcgcata ttcgtggagc aggtacagat attattacga tacaaggtgt tcagaaattg
      721 catggtacta gacaccaagt tattcctgat cgtattgaag cagggactta tatcgctttg
      781 gcggcagcta ttggaaaagg tgttaagatc actaatgttc tttatgagca tttagagagt
      841 ttcattgcta agttagaaga aatgggtgtc cgtatgacgg tagaagagga tgctatcttt
      901 gttgaaaagc aagaatccct caaggctatt acaattaaaa cctctcctta ccctggtttt
      961 gccactgatt tgcaacagcc attaacgccc ttgttgttaa aagcagatgg tcgtggaacg
     1021 attattgaca ctatatatga aaagcgcatt aaccatgtgc cagagttgat gcgcatggga
     1081 gcagatatct cagttattgg tggtcagatt gtttatcaag ggccgtctcg cctgacagga
     1141 gctcaggtca aagccactga tttacgtgcc ggagcggctc tagtgactgc tggtctaata
     1201 gctgaaggca agacagaaat tactaatatt gaatttatct tacgtggcta tgctagtatc
     1261 attgcaaaat taacagcact aggggcagat attcaattaa tcgaagacta aagagaagct
     1321 aacgcttctc ttttttatat tacatgtgct taggctaatg atacttaggt gcatactttg
     1381 ttgcatttta tggcttttta actgtcataa aaaagataaa aatgatatca ctaactaata
     1441 ttattaattt taatgctaaa ataatgagtt gacggta
//
LOCUS       DAUCXI010000100         1441 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.101, whole genome shotgun sequence.
ACCESSION   DAUCXI010000100 DAUCXI010000000
VERSION     DAUCXI010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1441
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.101"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..511
                     /locus_tag="VGY43_001788"
     CDS             <1..511
                     /locus_tag="VGY43_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HEQ4302932.1"
                     /translation="RFLNIKYIRIFGGIGCSVDDFLCNELFLSMLNETDIIFLIENEL
                     GTAVSTADDLIKIGHFIDEKSIKNLKIWFDIANYYRIDPKVGQLIQKLKNYIYYIHCK
                     NYIINDSGIYYVELGKGIINFKTLIHEIREHFINLIFSLEVHEKELDKKAEVVRKSYL
                     TLSEYIDGD"
     gene            513..1256
                     /locus_tag="VGY43_001789"
     CDS             513..1256
                     /locus_tag="VGY43_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEQ4302933.1"
                     /translation="MNLSIVGLKNIPYLKEGENLEKFIAESIKDSDFSIEDNNVLCIA
                     SKIVSISENQVLSLKQVQVSDEAKEIQKSIPRKDPRIIEIMLNLVDRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDKKSVDEVFLLPKNPDASAKRISEYLKLSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIPPLRKTAVIDSNGETIKFQEETLCDMIAASAGLVMGQRGT
                     GIPAVIIKGIEYEWSETTNIKDAINESSN"
     gene            1240..>1441
                     /locus_tag="VGY43_001790"
     CDS             1240..>1441
                     /locus_tag="VGY43_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEQ4302934.1"
                     /translation="MRVPIESKNILMVGFGKIGKIKAYKWMGRGYNVYVKDIKFCNLI
                     LLNKGISVDDDLSRQYFTIEICT"
BASE COUNT          546 a          147 c          283 g          465 t
ORIGIN      
        1 tagattccta aatattaaat atataagaat atttggtgga attgggtgtt cagtagatga
       61 tttcttgtgc aatgaactat ttttgagtat gttaaatgag actgatatta tttttttaat
      121 tgagaatgag ttagggactg ctgtgagcac tgcagacgac ttgataaaaa tagggcattt
      181 tatagatgaa aaatcgataa aaaatttaaa aatttggttt gatatagcta attattatag
      241 aattgatccc aaagtaggcc agcttattca aaaattgaaa aattatatct attatattca
      301 ttgtaagaat tatattatta atgattcagg aatatattat gtagaattag gaaaaggaat
      361 tatcaacttc aaaactctca ttcatgaaat ccgtgaacat tttataaatt taatttttag
      421 tttagaagta catgaaaaag aactggataa aaaggcagaa gtagtgagaa aatcctattt
      481 aaccctaagt gagtatattg atggagatta aaatgaattt aagtatagtt ggtttaaaga
      541 atattcctta tttgaaagaa ggtgaaaatt tagaaaagtt tattgcagag agtattaaag
      601 attcagattt ttctattgag gacaataacg tactttgcat agcttctaaa attgtgtcta
      661 tttcagaaaa tcaagttttg tctttgaaac aggttcaagt gagtgatgaa gctaaagaaa
      721 ttcagaagag catccctcgt aaagatccta gaataattga aattatgctc aacttagttg
      781 atagagacct gtcacgttta gatataaaaa aaaattacat tggatgtaga ttggaaaatg
      841 gtttaaagtt gacaagtggt ggaatcgata aaaaatcagt tgatgaagta tttctcttgc
      901 ctaaaaatcc agatgcttct gcaaaaagaa tctcagaata tcttaaactg tcacttggta
      961 agaacgtggc agttgttata actgatagtg atggtaggga ggataaaaga ggagctactc
     1021 aagtagcaat tggcatttat ggtattcctc cattgaggaa aacagcagta atagattcta
     1081 atggagagac aataaaattc caagaagaaa ctttatgtga catgattgca gctagtgctg
     1141 gtttagtaat ggggcaacgt ggaacaggaa ttcctgctgt tattatcaaa ggcatagaat
     1201 atgagtggtc tgaaacgaca aatattaagg atgcaattaa tgagagttcc aattgagagt
     1261 aaaaatattt taatggttgg atttggtaaa attgggaaaa taaaagctta taaatggatg
     1321 ggcagaggct acaatgtata tgtaaaagat ataaaatttt gtaatttaat attacttaac
     1381 aaaggaatca gtgtagatga tgatttatcg agacaatatt ttaccattga aatttgtact
     1441 c
//
LOCUS       DAUCXI010000101         1414 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.102, whole genome shotgun sequence.
ACCESSION   DAUCXI010000101 DAUCXI010000000
VERSION     DAUCXI010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1414
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.102"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(278..>1414)
                     /locus_tag="VGY43_001791"
     CDS             complement(278..>1414)
                     /locus_tag="VGY43_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEQ4302935.1"
                     /translation="GKIYFQIELGVDPITGKRIQKKGRKNQQGLPFNSFKEAYEEILR
                     LKHEFVNSTINNSFLTFREFMEEIYLKYYQQKVQFVTYQTALPHHQLFIKQFGSKKLS
                     DISTIDCERFRLAIIDKYSSNYAKNMWSRFKACLGYAERLGYIDRVPFKGLDNPRGKH
                     PDTKFWTFDEFKKVINSFDISEYEGLHNYMTIWLYFMTGLRVSEGIALKWEDIDFERK
                     WIHVHSTIEKDKNGVWYAKQQTKTVAGNRKIDLDDFTITILKKWREVQIKNDDKDYVI
                     SRFGAPLCKSTISRIIKRHAKITGVPEITGKGLRHSHASYLINVLHKDTLYVSYRLGH
                     ADKSTTLNTYSHWYYSGDSTISEEITSSLDNLGLSIYLPNSCQS"
BASE COUNT          464 a          262 c          177 g          511 t
ORIGIN      
        1 ctcctgaaca taaaaaaatt attactagac acatataaat ggaatagcca ctctactcag
       61 cttaattttt atagaaaata aaaatcctgc caaaaaattt ttggcaggat ttttggcaag
      121 aaaccaaatc attttatcag tttcttcaaa tcgctataag ctctaaaaaa ctgataaatc
      181 gggatttcgc tctcaaattg ctatctgctt cttatttaag agtaacaatt tgcaaatcct
      241 attttctccc agtattagtg ggttaattcc tcaattttca actctggcag gaatttggta
      301 ggtaaattga taatccaaga ttatctaaac tgcttgtaat ctcttctgaa attgttgaat
      361 cacctgaata ataccaatga ctatatgtat tcaacgtggt tgacttatca gcatgtccta
      421 atcgatatga aacgtataaa gtatccttat gtaacacatt tataagataa gaggcatggc
      481 tatgtcttaa acctttacct gtaatttctg gtacaccagt aatcttagca tgccttttta
      541 ttatcctaga aattgtagac ttacacaagg gggcaccaaa acgtgatatt acataatctt
      601 tatcatcatt cttgatttga acttctcgcc attttttaag tattgtaatc gtaaaatcat
      661 ctaaatcaat tttacgattc cctgctactg tctttgtttg ttgtttagca taccatacac
      721 cgtttttgtc tttctcaatt gtcgaatgaa catgaatcca tttacgttca aaatcaatat
      781 cttcccattt aagagcaata ccctcactaa ctcttaagcc agtcataaaa tatagccaga
      841 tcgtcatgta attatggagt ccctcatact cactaatatc aaaagagttt attaccttct
      901 taaattcatc aaatgtccaa aattttgtat cagggtgctt tcctctagga ttatctaatc
      961 ctttaaaagg aactctatca atataaccca atctttctgc atagcccaga catgctttaa
     1021 atctagacca catattttta gcatagttac tagaatactt gtctataata gctaagcgaa
     1081 atctttcaca gtcaatagta ctaatatctg ataatttttt actaccaaat tgcttaataa
     1141 ataactgatg atgtggtaaa gcggtctgat aagttacaaa ttgaactttt tgttgataat
     1201 attttaaata aatctcttcc ataaactctc taaaagttag aaaactatta ttaatagtag
     1261 agttcacaaa ttcatgtttt aaacgaagta tctcttcata tgcttcctta aaagaattaa
     1321 acggtagtcc ctgttgattt ttccttcctt tcttttgaat tcttttccca gttattggat
     1381 caactcctaa ttcaatttga aaatatattt ttcc
//
LOCUS       DAUCXI010000102         1411 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.103, whole genome shotgun sequence.
ACCESSION   DAUCXI010000102 DAUCXI010000000
VERSION     DAUCXI010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1411
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.103"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..743)
                     /locus_tag="VGY43_001792"
     CDS             complement(<1..743)
                     /locus_tag="VGY43_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEQ4302936.1"
                     /translation="MIEMLMDMLGTIRETDPSRTAIKDNTRVLSYCEVDTITNIVANQ
                     IVRKIGVNQRVAVILPHGINQILAMIAILKSNNCYVPIDYSLNGDKIKKIYSSTQAVM
                     YISDKNIPYVSKTNFLDVSEFITKKSDEKLPIENPFIYLREREAYILHTSGSTGEPKG
                     VIVSIANLDYIIRNLNTITPAVEESRYLFSTPYSFDVSITEMLGWIVSGSSVYCLDLS
                     VPSNYKCLAEIIFKNKITHLAFSPAAFLA"
BASE COUNT          490 a          241 c          165 g          515 t
ORIGIN      
        1 aatgctaaaa atgctgcagg agaaaaggct agatgcgtta ttttattttt aaaaataatt
       61 tctgctaaac atttataatt cgagggaaca ctcaaatcta gacagtatac gctactgccg
      121 ctcactatcc aacctaacat ttctgtgatc gatacatcaa aactatatgg tgttgaaaat
      181 aaatatctag attcttcgac ggcaggtgtt atagtattca agttccttat gatataatct
      241 aaattggcta tcgacactat tacacctttt ggttcacccg ttgatccaga tgtgtgcaaa
      301 atataagctt ctcgttctct aaggtatata aaaggatttt ctatcggcaa tttctcatct
      361 gatttctttg taataaattc tgaaacatcc aaaaaattcg tttttgaaac atacggaata
      421 tttttatcag atatgtacat cacagcttgg gtggatgaat aaattttttt aattttatct
      481 ccatttaaag agtaatctat cggaacataa cagttattcg attttaatat tgcaatcata
      541 gctaatattt gattaatccc atgtggtaag ataacagcaa cacgttggtt cacccctatt
      601 ttgcgaacta tttgattagc tactatatta gttattgtat ccacttcaca atatgaaagt
      661 actcttgtat tatcttttat agcagttcta ctcggatctg tttctctaat tgtccccaac
      721 atatccatta acatctcaat catactattc tcctttctaa aaaaatagat tcatattttc
      781 tattcctacc ttttaatatc aatatcaaaa ttcatactga cgttaacctt actgagtatt
      841 attaaaagaa ttgttcaaaa attgaatatt tttgtacctc agtaagaaaa ctgactcaga
      901 taatgattca caatctataa tagatgtatc gttatagttc aaagtaacaa caataaacta
      961 ttaatgcaaa caagcaaacc aacctattga atccactatt tatattaact aaatatgtta
     1021 aaatattcaa taaatcatcc tctctctata tttaattaga gtctttaagt ttactatact
     1081 ttagataatt gtatatcctc aacaaataaa atggtaataa atgtactgaa tgttcttcac
     1141 tactataatt gtaaatattt ttaaccgcat tagacaatat tctgtcccac tctacatcta
     1201 acagtccata tgaatacttg ttctcttctt gtaataaaaa taacgccttt ttctttaagt
     1261 tctcaatatc atcgttggaa gggatatcat ttgaatgaat aaaccgtctt aaatgattct
     1321 caaaatctat atttaaaatc catctgtctt tatttgaaaa atcatctttg atagtctcga
     1381 aaaaactttg agaaacttct aaaaaaattt t
//
LOCUS       DAUCXI010000103         1396 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.104, whole genome shotgun sequence.
ACCESSION   DAUCXI010000103 DAUCXI010000000
VERSION     DAUCXI010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1396
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.104"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            355..636
                     /locus_tag="VGY43_001793"
     CDS             355..636
                     /locus_tag="VGY43_001793"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ4302937.1"
                     /translation="MTVLNYVNTGDAKSIHNHLFHYTRQVRREVKVITIGILSAHYYE
                     ITMLFLQAKIILNCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
     gene            complement(1111..1198)
                     /locus_tag="VGY43_001794"
     tRNA            complement(1111..1198)
                     /locus_tag="VGY43_001794"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1162..1164),aa:Ser,seq:gct)
     gene            complement(1208..1281)
                     /locus_tag="VGY43_001795"
     tRNA            complement(1208..1281)
                     /locus_tag="VGY43_001795"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1245..1247),aa:Ile,seq:gat)
     gene            complement(1316..1386)
                     /locus_tag="VGY43_001796"
     tRNA            complement(1316..1386)
                     /locus_tag="VGY43_001796"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1352..1354),aa:Gly,seq:tcc)
BASE COUNT          482 a          296 c          181 g          437 t
ORIGIN      
        1 tttccatttt ccaattagaa tattagacat cttttttgac cttatcatta ttaatataag
       61 tatagtcaga ccttgttttt ttataagcta actatcgaaa actggtcatc tataaatctt
      121 agtattccat cactcaatca caattcataa agactcgcaa actttcacaa cttttaattc
      181 tatactttct gtagtaggta aatccacctc aaagattata gagtcttttt aaacatatgt
      241 aaaaagttcc atatgacgat ctataatgaa aagcgaccaa actatcattt cagaaagact
      301 catatagaat aatccgatta tagtataatt tcattaggaa tctaaaacct tagcatcacg
      361 gttttaaatt atgtaaatac tggggacgca aaaagcattc ataatcatct ctttcattat
      421 accagacagg ttagaaggga ggtcaaagtt attaccatag gcatactcag tgcccactac
      481 tatgagatta ctatgctttt tctacaggct aaaattatcc tcaattgttt tcatatcccc
      541 caacgtctta gacaagctat aactcgcttt cgtatccgaa tcataaatac ttctgctata
      601 aaacctatcg cgtatagaac tctcaaactt tactgaaaac tcatacagca tgattcacgg
      661 aagctcatca ataatagctt tattgcccaa tttttcgtac gcccataact aacatctaga
      721 aaagaaaagc tcttactcac aagatctctg aatttcaata attattccta actctatcaa
      781 ctcttgctct tcccattttt cagacaattt ttaaaatttt tctaaaagaa aagaacaaga
      841 ttagcaatat acttaaactc aactactcta aggccaaatt agaaacagtc aacaacctta
      901 tcaaagccat caagttaaac gttttacttc tctacagtag tcaaagagcc tatcatttta
      961 gttatcgaaa taatgaacga tttaaatatt ctatttagtt ggttttgaag attacaaaaa
     1021 aaagacgata accgtcttct ttccccttta tttataaatc atccattaat atgtttcatt
     1081 taacatatta accaaaatat ctttacaaaa cggagaataa gggattcgaa cccttgcgcc
     1141 agttacccga cctaacgatt tagcaaaccg tcctcttcag cctcttgagt aattctccaa
     1201 atatatatgg gcacgagtgg actcgaacca ccgacctcac gcttatcagg cgtgcgctct
     1261 aaccacctga gctacgcgcc caagctttta ttgatatagc ttgggaaaac tataaagcgg
     1321 gtgacgagaa tcgaactcgc gacaacagct tggaaggctg tagttttacc actaaactac
     1381 acccgcaata tgataa
//
LOCUS       DAUCXI010000104         1334 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.105, whole genome shotgun sequence.
ACCESSION   DAUCXI010000104 DAUCXI010000000
VERSION     DAUCXI010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.105"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            434..>1334
                     /locus_tag="VGY43_001797"
     CDS             434..>1334
                     /locus_tag="VGY43_001797"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEQ4302938.1"
                     /translation="MYSALLGNPVEHSISDELFEYLNNIIGGLDDYKHKKILVNSVCL
                     EEKIKNLINDPQCIGLNITLPYKRETMKYIDTLDKVAEVTGSVNNIYKTGDIIIGTNT
                     DWKGIYDTLDFFNVNHLKKCCIWGTGGTSRAAIFALRKLQISPVIVYREPISENTWSL
                     MESFSDLKFITYQELVNQQLLNDIEIIINTTPVGMVNYEDDLPINLKQLDSINYEDKY
                     FMDVVFNPLHTKLHKYFSSKGVKIIDGLWVLLFQGIEAFSLWCDKINDSKYFLLKDDI
                     VRIHKFLERKIQETDGFSYNSKSR"
BASE COUNT          503 a          137 c          236 g          458 t
ORIGIN      
        1 aaatggattc gcagagtgtt cgtggtttat tttattgaac tattttggtt ttcaatatga
       61 tgaaatagtt agaataatca ataaaaaatc agaaaaaaga acagtagatg ctcctaggta
      121 tagtttgatt ggctctagcg agaatgcgtt aacgttttct ccatattgtg agtatagatt
      181 tgaagataat catatattgt gtcatacaga aaatgaaaat caattttact ttggtaaatg
      241 taaactgcct ttaaataaaa acggaaagga agtctaagaa tgaagaaatt tagaaacttt
      301 tcacgatttt gattttgttg atggatatta tcattattgt tggtggctaa gatacttagg
      361 aataatatat aacagtgtgt aacaaatatt tttaattagt agtatcttat ttaaaaaagt
      421 ggggaggaat attatgtatt ctgcattact tggtaatcca gtggaacatt ctatatcgga
      481 tgaattattt gaatatctaa ataatattat aggaggttta gacgactata aacataagaa
      541 aattttagtg aactcagtgt gtttagaaga aaaaattaaa aatctaataa atgatccaca
      601 atgcattgga ttaaacataa ctttacccta taaaagagaa acaatgaaat atattgatac
      661 tttagataaa gtagctgagg taaccggttc tgttaacaat atttacaaaa ctggagatat
      721 tattatagga actaatactg attggaaagg tatttatgat acattagatt ttttcaatgt
      781 taaccattta aaaaaatgtt gtatttgggg tactggaggt acttcaaggg cggctatttt
      841 tgctttacga aaactacaaa tctcaccagt cattgtatat agagagccaa ttagtgaaaa
      901 tacatggagt ttaatggaaa gtttttctga tctaaagttt attacatatc aggaattggt
      961 caatcaacaa cttttaaatg atatagagat cataataaat actacaccag ttggaatggt
     1021 aaattatgaa gatgatttac ctataaatct taagcagtta gatagtatta attatgaaga
     1081 taaatacttt atggatgtag ttttcaatcc tttacacact aagcttcata aatattttag
     1141 tagtaaagga gtaaaaataa tagacggttt atgggtttta ctttttcaag ggatcgaggc
     1201 attttcattg tggtgcgata aaatcaatga tagtaagtat tttttactaa aagatgatat
     1261 agtacggata cataaatttt tggaaaggaa gatacaagaa acagatggtt tttcatataa
     1321 cagtaaatct cgat
//
LOCUS       DAUCXI010000105         1320 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.106, whole genome shotgun sequence.
ACCESSION   DAUCXI010000105 DAUCXI010000000
VERSION     DAUCXI010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.106"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(429..1295)
                     /locus_tag="VGY43_001798"
     CDS             complement(429..1295)
                     /locus_tag="VGY43_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4302939.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLENGEFTPG
                     ADFLYALSKKLKVSIDYFFNEQIVEEIDELSEFKKLAQTFITNRNYESLKYIYELESV
                     KVHRLSLVNKFYMEWIKSLIDFYFYGQKEEAVARLEKVLSQLNVTDLFYLQVSNTLFN
                     FYYDIEDLESFNEIREKLECQVNQLKLNTIEELNLSIKFNYNVCRYLWLQNNTEEAIT
                     KITDTIKQCKTYRTTYLLADLYVLMGNVSKNFSSKVAVKEYFETAYFLYKLEGNMSMA
                     LKIEHYIADITE"
BASE COUNT          419 a          242 c          146 g          513 t
ORIGIN      
        1 ctccttacaa atataatgat gatttaaaca actttttaaa ctatatttta ctcccttcaa
       61 tacatctgcc aggatataga attcaaacat caacaatttt aatcctcttt tttaatatat
      121 taattttttt ctaatatcta aatttttatc tagaaacacc gtttgcagga ccaggatcaa
      181 tttctgttgc ctttatatga gattggggtt tcgatacaat ccctaacaga attaaaacta
      241 taactactaa agtaacaatt tttttaaaca aatttttcat atttctctcc tcttttttgc
      301 ctttagttta tcacttcgat gttattatgt caacaatttt ataaggtttt tttatttttt
      361 tttattaaat acatatttgt attattttgg attaaaaaaa aacgatgctt aattgaacat
      421 cgtctttgct attctgttat atctgcaata taatgctcga ttttaagagc cattgacata
      481 ttgccctcaa gcttatatag gaaataagcc gtttcaaagt actcttttac tgcaacttta
      541 gaagaaaaat tcttactgac atttcccatc aatacataca aatcagccaa aagatatgtt
      601 gttctatacg tcttacattg ctttatcgta tctgtgattt tagtaatagc ctcttcagta
      661 ttattctgca accatagata gcgacaaaca ttataattaa atttaataga aaggtttaat
      721 tcttcgattg tgtttaactt gagttgattt acttgacact ccaacttttc tcgaatttca
      781 ttaaagctct ctaaatcttc aatatcataa taaaaattaa atagagtatt tgaaacttga
      841 aggtagaaca ggtcagttac atttaactga gacagtacct tctccaatct tgccacagct
      901 tcctcttttt gcccatagaa ataaaaatct ataagagatt ttatccactc catataaaat
      961 ttatttacta gagacaagcg atgtaccttt acactctcta attcatatat atacttcaaa
     1021 gactcataat ttcgatttgt gataaatgtc tgggctaact tcttaaactc tgatagctca
     1081 tcaatctctt ctacaatttg ctcattaaaa aaataatcta tactaacttt taacttctta
     1141 gacagagcat ataaaaagtc tgctcctgga gtaaattctc cattctctaa tcgactaatc
     1201 tgtccctgtt tacatatccc ctcggccaat tctcgctgag acatttttaa ttcttttcgt
     1261 ctatttttta atctggttgc taatagtgtg cccacgtttg cattttcctt ttctattcga
//
LOCUS       DAUCXI010000106         1063 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.107, whole genome shotgun sequence.
ACCESSION   DAUCXI010000106 DAUCXI010000000
VERSION     DAUCXI010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.107"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..111)
                     /locus_tag="VGY43_001799"
     CDS             complement(<1..111)
                     /locus_tag="VGY43_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEQ4302940.1"
                     /translation="METVNYKDLVAIGFPEHTSRNIIRQAKKIAVKKFEEA"
     gene            complement(419..640)
                     /locus_tag="VGY43_001800"
     CDS             complement(419..640)
                     /locus_tag="VGY43_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEQ4302941.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
BASE COUNT          359 a          194 c          151 g          359 t
ORIGIN      
        1 agcttcttca aactttttta cagcaatctt ttttgcttgt ctaataatat tcctcgatgt
       61 gtgctctgga aaaccaatcg caactaaatc tttatagttt actgtttcca tgattttact
      121 acttcctttc ttagattttt tcacctccat ggcatgactg atgaagtcat cataagaatt
      181 tcacttgctg ctcttttacg gtggcagcct gaacggtcag aagtatcatt gtatatcatt
      241 tgtatcatgg catataaagt atcgctctat tttattgatg gtttttatat cgctcttatc
      301 atggcgagcc attcaaaact gctccacaaa tgaggaaagt accattttgg actatttaat
      361 tgtcaaagaa ccaaataaaa taatctcctc attttcacac tctatgaaat tgaggagatt
      421 attttctaaa gcgaatttta tcaggaaaat ctgtcaatcc caataggtag tctgtactga
      481 catcgtaaaa gtttgagaga gttaccaata catctgctgt taacgtatgc tcaccccgtt
      541 caattttagc ataagctgag tttgtaaacg aaagtatttt agctatttgt ttttgggtca
      601 aatcgtgatc ttccctcaaa tctctcaaac gtctgtacat ctagctttct cctgagaaaa
      661 gtataatata taaaactaag aaatcattca aagtgtccta actggacatt ttgaactaaa
      721 attaatctat taaacatatc tcataagcat atctattata ggtaagacaa tattaagaaa
      781 gacggtcaaa atctattaac cgtctaaaaa tgttataagc tattaaaaaa tcagcagtaa
      841 tccggtaaca aaagtcacat aattttgtta aggaagggat taatgatgtc cagattacta
      901 ctaaccagca aattgaaaaa tgctcaacat gatatttcta agatgaatct cttactttca
      961 gaacctaaaa gttgaataat agccactccc tacttatcaa taaaattatc cgttgcatta
     1021 acagatgtat ataaaccaat ccatggattt caaagcaatt aac
//
LOCUS       DAUCXI010000107         1012 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.108, whole genome shotgun sequence.
ACCESSION   DAUCXI010000107 DAUCXI010000000
VERSION     DAUCXI010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1012
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.108"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(<1..>1012)
                     /locus_tag="VGY43_001801"
     CDS             complement(<1..>1012)
                     /locus_tag="VGY43_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEQ4302942.1"
                     /translation="RGGPSKMGRKRKKNLEEMTEVERLQKELEYPRAENAVLKKLREY
                     RLRRRSKTQRATEIIQALRNQFPLEMLLEILDLSRSTYYYQVKRLAQGDKDIELKHVI
                     REIYDEHKGNYGYRRIHMELRNRGFVVNHKKVQRLMKVMGLAIRIRRKRKYSSYKGEV
                     GKKADNLIKRHFEGSKPYEKCYTDVTEFALPEGKLYLSPVLDGYNSEIIDFTLSRSPN
                     LKQVQTMLEKTFPADSYSGTILHSDQGWQYQHQSYHDFLESKGILPSTSRKGNSPDNG
                     MMESFFGILKSEMFYGLETTYQSLDKLEEAITDYIFYYNNKRIKAKLKGLSPVQYRTK
                     SF"
BASE COUNT          264 a          214 c          195 g          339 t
ORIGIN      
        1 tgaaaggatt tagttctgta ttggacagga ctaagtcctt ttagttttgc tttaattcgt
       61 ttgttgttgt agtaaaaaat gtaatctgta atagcttctt caagcttgtc aagtgattga
      121 taagttgtct cgagtccata aaacatttca gatttgagaa tgccaaagaa ggattccatc
      181 atgccgttat ccgggctatt ccctttgcgg gacgtggatg gcaaaatacc tttagactct
      241 aaaaaatcat ggtaggactg gtgttggtat tgccacccct ggtcactatg aagaatagtt
      301 ccgctgtatg aatccgctgg aaaagtcttc tcaagcatgg tttgaacctg tttcaagtta
      361 ggagaccgag acagagtgaa atcaataatc tcactgttat agccgtcaag aacaggtgat
      421 aagtagagtt ttccttcagg taaggcaaac tccgtcacat cagtgtaaca tttttcgtaa
      481 ggtttagagc cttcgaagtg acgtttaatc agattatcag ccttcttacc aacctctcct
      541 ttgtaagaag aatacttgcg cttccgacga atgcggattg ctaggcccat gactttcatg
      601 agacgttgaa ctttcttatg attgaccaca aatcctcggt tacgcaactc catatgaata
      661 cgacgataac cgtaattacc tttatgctca tcataaatct ctcgaatcac atgctttagt
      721 tctatatcct tatctccttg agctagtcgc ttcacttgat agtaataggt ggagcgtgat
      781 aaatcaagga tttcaagtag catctctaag ggaaattgat tccttaatgc ttgaatgatt
      841 tctgttgctc tttgagtttt gcttcgtctt ctcaagcggt attctctcag cttttttagc
      901 acagcattct ccgctctagg gtattctaat tccttctgaa gacgttcaac ctctgtcatc
      961 tcttccaaat ttttcttacg tttacgcccc atcttactcg gtccccctct tg
//
LOCUS       DAUCXI010000108          930 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.110, whole genome shotgun sequence.
ACCESSION   DAUCXI010000108 DAUCXI010000000
VERSION     DAUCXI010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.110"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            21..188
                     /locus_tag="VGY43_001802"
     CDS             21..188
                     /locus_tag="VGY43_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEQ4302943.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(248..385)
                     /locus_tag="VGY43_001803"
                     /pseudo
     CDS             complement(248..385)
                     /locus_tag="VGY43_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            669..752
                     /locus_tag="VGY43_001804"
                     /pseudo
     CDS             669..752
                     /locus_tag="VGY43_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            801..884
                     /locus_tag="VGY43_001805"
     CDS             801..884
                     /locus_tag="VGY43_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEQ4302944.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT          304 a          129 c          179 g          318 t
ORIGIN      
        1 ttataaacta caagtggata ttgtgtcctg tatgtggaaa taaaacacga ttaaagataa
       61 gggaagatac tgaattaaaa aaattccccc tctattgtcc gaaatgcaga caagaaaatt
      121 taattgaaat aaagcagttc aaagtaactg tgattacaga gccagacgca aagacgcaga
      181 gccgataaaa tgagattaat acaatctcat tttatcggct ctttccgtta tgtatggatt
      241 cttttaatta gtcttcgatg tttcttgctt cgttgatacc gctggctaaa gattccatta
      301 aggatagttc tttgtctgta aagctatcca tgtatttctc tatctgtaat cgtcgggtgc
      361 tttttaccaa gttattagca ggtaggggtc ccgagcgcct acgaggaatt tgtatcgata
      421 agaaatagat ttaaaaattt cgctgttatt ttgtacattt aacttgacgg tgacatctct
      481 ctattgtgag ttattagtgg tacagttttc aaccgtttta attataaaaa agtggtgcat
      541 ttttaaattg gcacaaacag gtaacggtta ttgcaggtgt atttcttatc tatgggttta
      601 acatggattt tatcattaaa atcatgagta ttgtccgaga gtgattggtc ttgcgtatgg
      661 ttaaccctaa agttatggaa ataagactta gaagcaaact taagagtgtg ttgattgtgc
      721 attatcttaa aattttgtat aataggaatt gaagttaaat tagatgctaa aaatttgtaa
      781 ttaagaagga gggattcgtc atgttggtat tccaaatgcg taatgtagat aaaacatcta
      841 ctgttttgaa acagactaaa aacagtgatt acgcagataa ataaatacgt tagattaatt
      901 cctaccagtg actaatctta tgacttttta
//
LOCUS       DAUCXI010000109          828 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.111, whole genome shotgun sequence.
ACCESSION   DAUCXI010000109 DAUCXI010000000
VERSION     DAUCXI010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.111"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            5..78
                     /locus_tag="VGY43_001806"
     tRNA            5..78
                     /locus_tag="VGY43_001806"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Asn,seq:gtt)
     gene            158..231
                     /locus_tag="VGY43_001807"
     tRNA            158..231
                     /locus_tag="VGY43_001807"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:192..194,aa:Arg,seq:acg)
     gene            257..808
                     /locus_tag="VGY43_001808"
     CDS             257..808
                     /locus_tag="VGY43_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEQ4302945.1"
                     /translation="MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRH
                     YYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYLKDLLRRQESQ
                     KRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSPERMQFQALIRGE
                     RFKGRRALLRKISPYFKEFAQQL"
BASE COUNT          265 a          130 c          199 g          234 t
ORIGIN      
        1 tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat gtcgtaggtt
       61 cgagtcctac tggcggagta gagagaggta ggaagcgtcc tatctttttt tgcattttag
      121 agaagagtgt ggtaagatag aggcaagata tgcgttggca cccttagctc aactggatag
      181 agtacctgac tacgaatcag gcggttagag gttcgactcc tctagggtgc ataatgaaaa
      241 aaacaacagg acactaatgt cctgttgttt ttttgtggtt ctctttatac tagggatagt
      301 taaaaagaaa aggagactca aaatgtcgat agagacaaga gcagcgtttg aaaaagttaa
      361 gcccattatt ttgaaattaa agcgacacta ttatattcaa ttgtgggata gagatgactg
      421 gttacaagaa ggacatatta ttttattaca gttactagaa aggtacccag agttaattga
      481 ggaagaagag cgtttatatc gctattttaa aacaaaattt tcatcttatt tgaaagattt
      541 attacgccgt caagaaagtc aaaagcgtca gttccataag ttagcatatg aagagatagg
      601 ggaggttgca catgccattc catcgagagg gttatggcta gacgactatg tggcttatca
      661 agaggtaata gctagcttag agaaccaatt aaattcgcca gagcgtatgc agtttcaagc
      721 acttatcagg ggcgaacgtt tcaagggaag acgtgctcta cttaggaaga tcagtcccta
      781 ttttaaggaa tttgcacagc agttgtaagc aagacctata aggaattg
//
LOCUS       DAUCXI010000110          800 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.113, whole genome shotgun sequence.
ACCESSION   DAUCXI010000110 DAUCXI010000000
VERSION     DAUCXI010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.113"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..>800
                     /locus_tag="VGY43_001809"
     CDS             <1..>800
                     /locus_tag="VGY43_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HEQ4302946.1"
                     /translation="YVGLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSSLKEAAINKL
                     LCKTKNINATSSEELAYKDATFIILSLPTNLKVNKLDTSIIEISVSNILKINKKATIV
                     IKSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNESRNSQLFLD
                     ILTDISVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNELDTFAEMQNLDSKKIIE
                     AIGYDQRIGNSHNNPSFGFGGYCLPKDIKQLEYHFKEIPAPIITSISES"
BASE COUNT          288 a          124 c          128 g          260 t
ORIGIN      
        1 tacgttggat tatcgatagg actcctactt gcaaaggaac acgacgttac cttttttgat
       61 attgataata aaaaaattga tttaataaat aaaaggcaat cctctcttaa agaagcagct
      121 ataaacaaac ttttatgtaa gacaaaaaat attaatgcaa cttcttctga agaattagca
      181 tataaggatg cgactttcat aatcttgtct ttgccaacca acctaaaagt taataagctt
      241 gatacttcca ttatcgaaat ttctgtaagt aatattttaa agataaacaa aaaggctaca
      301 attgtaataa agtcgacagt tccaattggt tttacagaat atttaaggaa tcgatttcac
      361 tacaacgata tcattttttc acctgagttc cttagggaag gatcaactat tcatgatcaa
      421 ttgtatcctt cgagaactat agttggaaat gaatctagaa attctcaatt attcttagac
      481 atactaacag atatatcggt tgaaaaagac tcgccatctt tattagttgg ctcttctgaa
      541 gcagaagcga taaagttatt ttcgaatgca tacttggcac aaaaaattgc tttttttaat
      601 gagttggata cgtttgctga aatgcaaaat ttggactcaa aaaaaattat tgaggctata
      661 ggatatgacc agagaatagg aaattcgcac aataatcctt ctttcggttt tggtgggtac
      721 tgtcttccta aggatattaa gcaattagag tatcatttta aagaaattcc agcaccaatt
      781 attaccagta taagtgagtc
//
LOCUS       DAUCXI010000111          778 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.114, whole genome shotgun sequence.
ACCESSION   DAUCXI010000111 DAUCXI010000000
VERSION     DAUCXI010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..778
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.114"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            95..721
                     /locus_tag="VGY43_001810"
     CDS             95..721
                     /locus_tag="VGY43_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEQ4302947.1"
                     /translation="MEKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLETLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEILRKDKGYYVLRSIKQA"
BASE COUNT          288 a           97 c          150 g          243 t
ORIGIN      
        1 ttctaacaaa tagttaaagt tcggttttta tttgtaatat agagaaaatt gttaagaaac
       61 aagcgtcttg taaaccattt caaagtatga tagaatggaa aagtacctta aaaagatagg
      121 aaaaatgatg acaaagatgt attatgatga aaatccagat agcctacacg atattcatga
      181 agtaaaagta gagctgctta atcatccctt tacttttttg acggattcag gtgtcttttc
      241 aaagaaaatg gttgatttcg gtagccaagt attattagag acactaaatt tcaaggagaa
      301 cgaacgtgta ctggacttag gttgcggcta tggtcctctt gggattagtc tagccaaggt
      361 tcaaagggta gacgcaacct tagtggacat caataatcgt gctcttgatt tagctagaaa
      421 aaatgcaact aataaccaag tggcagtaac tatttttcaa tcaaatattt atgaaaatat
      481 tagtggccat tttgagcata ttattagtaa tcctcctatt agagcaggaa agagagtagt
      541 tcatagtatt attgaaaaaa gcatagattt tttagtggtt aatggtgact taacgattgt
      601 gattcaaaaa aaacaaggag ctcctagcgc taaagcaaaa atggcaacta tttttggtaa
      661 tgttgagata ttaaggaaag ataaaggtta ttatgtatta agaagtataa agcaagccta
      721 atttaaataa tcaacaattg ctcattttaa ttaggtttgc ttaaatagta aagagtta
//
LOCUS       DAUCXI010000112          756 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.115, whole genome shotgun sequence.
ACCESSION   DAUCXI010000112 DAUCXI010000000
VERSION     DAUCXI010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..756
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.115"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..>756
                     /locus_tag="VGY43_001811"
     CDS             <1..>756
                     /locus_tag="VGY43_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEQ4302948.1"
                     /translation="DVPHFIFQNIKEQDNKIRCSSETIKILGSVKFIESNQQYIKYNG
                     NGSILVYGRLDYFKEGISLYYIGEYLAECLLIEQDNTLLIHAASVYNPITDHSILLLG
                     DKGAGKTTVALRLCIEHGYHLIGNDQVIFGLDSGILVTCAGTSFFKIRRTAVLSDKLL
                     FRLFSKYFNHPSHFNQASWDDKISIDPGELGIRTCNFSVEISEIYYIKADKQEKQICQ
                     SIWNDSLASLFLNEILGRHISGQVACFQSDKGK"
BASE COUNT          278 a           92 c          133 g          253 t
ORIGIN      
        1 ttgatgtacc tcactttata tttcaaaata taaaagagca ggataataaa ataagatgtt
       61 ctagcgaaac aataaagatt ttaggtagtg taaaatttat tgagagtaat caacaatata
      121 taaaatataa tggcaatgga agtattttag tttatggtag attagattat tttaaagaag
      181 gtatttcact atattacatt ggagagtatt tagctgagtg tcttttgatt gagcaggata
      241 atacattatt aattcatgca gcgtcagttt ataatcctat aacggatcat tcaattttac
      301 tcttagggga taaaggtgct ggaaaaacta ctgtcgcact cagactttgt atagaacatg
      361 gataccacct tataggtaat gatcaagtaa tatttggctt agattctgga atattagtaa
      421 cttgtgcagg aacctcattc tttaaaatta gaagaacagc tgttttgtca gataaattac
      481 tatttagact gtttagtaaa tattttaatc atccatcaca cttcaatcag gcaagctggg
      541 atgataaaat ttcaattgac ccaggagagt tagggatacg tacttgtaat ttttctgttg
      601 aaatttcaga aatttattac ataaaagcag acaaacaaga aaaacaaata tgtcaatcaa
      661 tttggaatga tagtttagcc agcttatttc taaatgaaat attgggaaga catatatctg
      721 gacaagttgc atgttttcaa tcagataaag gaaagt
//
LOCUS       DAUCXI010000113          735 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.116, whole genome shotgun sequence.
ACCESSION   DAUCXI010000113 DAUCXI010000000
VERSION     DAUCXI010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.116"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            7..717
                     /locus_tag="VGY43_001812"
     CDS             7..717
                     /locus_tag="VGY43_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEQ4302949.1"
                     /translation="MATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEYKDLVTYQ
                     GTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRLDKDTRGL
                     LLLTNNGQLAHDLLSPKKHVTKEYLAKVVGIMTEADKDYFARGISLKDHQCLPAHLEV
                     LASDLQQQTSLVKITIQEGKFHQVKRMVAACGKGVLDLQRLSMGPLKLDPSLAEGEFR
                     RLTPEELQSLAPYCQSSL"
BASE COUNT          222 a          150 c          170 g          193 t
ORIGIN      
        1 tttttagtgg caactggtgt tggaactagg agccaagtca aacttctctt aaaaaagaag
       61 gctattttcg tcaatcaaaa ggttgaaacc tctgccaaag cacacattga tgaatacaag
      121 gatttggtga cgtatcaagg cacgcccttg gtctatgaat cctttgttta ttacctgtta
      181 aacaagccgt cagggtatgt gtcagcaacc caggacagac agcaggctac tgttatggag
      241 ttgttagatg acacggctag gcaaaaagca gtttttcctg tgggtaggtt agataaggat
      301 acccgtggac ttttgctctt gaccaataat ggacaactag cccatgacct tttatcccct
      361 aaaaaacatg ttacgaaaga gtacttggct aaagtagtag gcatcatgac tgaagctgat
      421 aaagattatt ttgctagagg tatttcctta aaggatcacc agtgcctacc tgctcattta
      481 gaagtgcttg ctagtgattt acagcagcaa acaagtttgg ttaaaattac catacaagaa
      541 ggaaaattcc atcaggtgaa acgcatggta gcagcctgtg gaaagggagt gcttgacttg
      601 cagcgtctca gcatgggacc attaaaacta gaccctagcc ttgcagaagg ggagtttagg
      661 cgcctgacgc ctgaggaatt gcaaagcctg gcaccttatt gtcagagctc actataaaaa
      721 gaaacctccc ctgtc
//
LOCUS       DAUCXI010000114          488 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.120, whole genome shotgun sequence.
ACCESSION   DAUCXI010000114 DAUCXI010000000
VERSION     DAUCXI010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.120"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
BASE COUNT          164 a           54 c           94 g          176 t
ORIGIN      
        1 ttgatacttt gagtagtaac gataatattt aattttttga tggattactt taattgactt
       61 tagtgtgtta gatgccagtt tggatttttg atatttgtgt tgagtttaaa agataaaaac
      121 acttaatgaa aatctgtttt ttcttagaaa ggggaccagt atgattgaga cgctaatgag
      181 tacgttggaa atggttagaa aaaaatccta gtaggactgc aatcgaagat gactttgagg
      241 aatataaaaa gagaaatcta ccaatctttg tcagtgaaga tgatagtgtg atctattata
      301 gaccagggtt catttttaat gaattctatc ccaatatttc aggttggaga caagaactaa
      361 agactaagct tactagtatt tctttaattt ctttacattt tattggtgtt gttgacgaac
      421 aaaaaaaggg ggaatatcta ggttcttttt ctgatacatc tgaattctta agtagacatc
      481 caaaaatt
//
LOCUS       DAUCXI010000115          425 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.121, whole genome shotgun sequence.
ACCESSION   DAUCXI010000115 DAUCXI010000000
VERSION     DAUCXI010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.121"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(62..135)
                     /locus_tag="VGY43_001813"
     tRNA            complement(62..135)
                     /locus_tag="VGY43_001813"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(99..101),aa:Met,seq:cat)
     gene            complement(145..234)
                     /locus_tag="VGY43_001814"
     tRNA            complement(145..234)
                     /locus_tag="VGY43_001814"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(196..198),aa:Ser,seq:tga)
     gene            complement(257..330)
                     /locus_tag="VGY43_001815"
     tRNA            complement(257..330)
                     /locus_tag="VGY43_001815"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(294..296),aa:Ile,seq:cat)
     gene            complement(351..424)
                     /locus_tag="VGY43_001816"
     tRNA            complement(351..424)
                     /locus_tag="VGY43_001816"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(388..390),aa:Met,seq:cat)
BASE COUNT          113 a          120 c           98 g           94 t
ORIGIN      
        1 ggagcttcaa tccattgctc taccaactga gctaccgagc caacaactac atacttatgt
       61 attgcgggag caggatttga acctacgacc ttcgggttat gagcccgacg agctacctaa
      121 ctgctccatc ccgcgatagt taaaaggagg atgtgggatt cgaacccacg cacgctttta
      181 cacgcctgac ggttttcaag accgttccct tcagccggac ttgggtaatc ctccaaaata
      241 atgattatct atgatatgga ccttgtagga ctcgaaccta cgaccgctcg gttatgagcc
      301 gagtgctcta accagttgag ctaaaggtcc caagtcatcc ataaaaataa tagcggcgaa
      361 ggggatcgaa cccccgacct cccgggtatg aaccggacgc tctagccagc tgagctacac
      421 cgcca
//
LOCUS       DAUCXI010000116          371 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.122, whole genome shotgun sequence.
ACCESSION   DAUCXI010000116 DAUCXI010000000
VERSION     DAUCXI010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.122"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..>371
                     /locus_tag="VGY43_001817"
     CDS             <1..>371
                     /locus_tag="VGY43_001817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEQ4302950.1"
                     /translation="SLLCRYGLTSAAALLLTFGGVSAVKADEQSNIEALQSQLQALRE
                     NLPKVGDNIPKHDVFRQHVFYKHLEEFEARLDFYLKTLDGSLSQLQGPRGEKGDQGPR
                     GEQGLRGEIGPEGPQGKTGPAG"
BASE COUNT          104 a           76 c          100 g           91 t
ORIGIN      
        1 agccttcttt gtcgctatgg cttaacctca gcggctgctc ttttgctgac ctttggaggt
       61 gtaagcgcgg ttaaggcgga tgagcaaagt aatattgaag cactacagag tcaattacag
      121 gctttacgcg aaaatttgcc taaggtcgga gataatattc ctaagcatga tgttttcagg
      181 caacatgtgt tttataaaca tttggaagag tttgaagctc gactggattt ttacttaaaa
      241 acgttggatg ggagtctatc ccaactgcaa ggtccacgtg gtgaaaaagg agaccagggc
      301 ccacgtggtg aacaagggct acgaggcgaa atcggtcctg aaggcccaca aggcaaaacc
      361 ggcccagcag g
//
LOCUS       DAUCXI010000117          355 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.125, whole genome shotgun sequence.
ACCESSION   DAUCXI010000117 DAUCXI010000000
VERSION     DAUCXI010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.125"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..274
                     /locus_tag="VGY43_001818"
     CDS             <1..274
                     /locus_tag="VGY43_001818"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HEQ4302951.1"
                     /translation="TRPNLVNQCFQATGKNKLWLGDLTYIPTQEGILYVSVLIDVYSR
                     KIVGWAMGRRMQDKLVTEAFNQAYNREKPKEGVIVHTDQGSQYTGA"
BASE COUNT          123 a           61 c           78 g           93 t
ORIGIN      
        1 aactcgtccc aatcttgtta atcaatgttt ccaagcgact ggtaagaata aattatggct
       61 aggagactta acctacattc ctacacaaga aggaatactt tatgtgtctg tcttgataga
      121 cgtttatagt agaaagattg ttggttgggc aatgggccga cgtatgcaag acaagttggt
      181 aacagaggct ttcaatcaag cttataatag agaaaagcct aaagaagggg taatcgtcca
      241 tacagatcag ggttctcaat ataccggagc atgatttcag gacctactta gacagaaaaa
      301 atgtaagtcc agtatgagtc gaaaaggtaa tccatacgat aatgcactca tggaa
//
LOCUS       DAUCXI010000118          355 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.126, whole genome shotgun sequence.
ACCESSION   DAUCXI010000118 DAUCXI010000000
VERSION     DAUCXI010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.126"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..274
                     /locus_tag="VGY43_001819"
     CDS             <1..274
                     /locus_tag="VGY43_001819"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HEQ4302952.1"
                     /translation="TRPNLVNQCFQATGKNKLWLGDLTYIPTQEGILYVSVFIDVYSR
                     KVVGWAMGRRMQDKLVTEAFNQAYNREKPKEGGIVHTDQGSQYTGA"
BASE COUNT          121 a           60 c           81 g           93 t
ORIGIN      
        1 aactcgtccc aatcttgtta atcaatgttt ccaagcgact ggtaagaata aattatggct
       61 aggagactta acctacattc ctacacaaga aggaatactt tatgtgtctg tctttataga
      121 cgtttatagt agaaaggttg ttggttgggc aatgggccga cgtatgcaag acaagttggt
      181 aacagaagct ttcaatcaag cttataatag agaaaagcct aaagaagggg gaatcgtcca
      241 tacagatcag ggttctcaat ataccggagc atgatttcag gacctgctta gatggaaaaa
      301 atgtaagtcc aggatgagtc gaaaaggtaa tccatacgat aatgcactca tggaa
//
LOCUS       DAUCXI010000119          330 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.128, whole genome shotgun sequence.
ACCESSION   DAUCXI010000119 DAUCXI010000000
VERSION     DAUCXI010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.128"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(52..133)
                     /locus_tag="VGY43_001820"
     tRNA            complement(52..133)
                     /locus_tag="VGY43_001820"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(97..99),aa:Leu,seq:tag)
     gene            complement(139..211)
                     /locus_tag="VGY43_001821"
     tRNA            complement(139..211)
                     /locus_tag="VGY43_001821"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(176..178),aa:Lys,seq:ttt)
     gene            complement(243..315)
                     /locus_tag="VGY43_001822"
     tRNA            complement(243..315)
                     /locus_tag="VGY43_001822"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(280..282),aa:Asp,seq:gtc)
BASE COUNT           87 a           93 c           68 g           82 t
ORIGIN      
        1 tgattacaaa tcagatgctc taccaactga gctaagccgg ctaatctttt atgcgggtta
       61 agggacttga acccccacgc cgttaagcgc cagatcctaa atctggtgcg tctgccaatt
      121 ccgccaaacc cgcttttatg acccgtactg ggctcgaacc agtgacccat tgattaaaag
      181 tcaattgctc taccaactga gctaacgagt cttttcttca aaaaatatga ctactctttg
      241 aacggtcccg acgggaatcg aacccgcgat cttcgccgtg acagggcgac gtgataaccg
      301 ctacactacg ggacctgtat tttccaatac
//
LOCUS       DAUCXI010000120          293 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.129, whole genome shotgun sequence.
ACCESSION   DAUCXI010000120 DAUCXI010000000
VERSION     DAUCXI010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.129"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            20..>293
                     /locus_tag="VGY43_001823"
     CDS             20..>293
                     /locus_tag="VGY43_001823"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEQ4302953.1"
                     /translation="MNSHHACQTLQVSRSGFYAYLKRRPSSRHVENEALKEMIKAIFY
                     EHKERYGSVRITQELCRRGIHVNHKRVGRLLHQLGLYAKGSRYQYKY"
BASE COUNT           92 a           56 c           58 g           87 t
ORIGIN      
        1 gaaggaaaat agtgttagct tgaatagtca tcacgcctgt caaactcttc aagtctcccg
       61 ttcaggtttc tatgcttatt taaaacgtcg tccctcttca aggcatgttg agaatgaagc
      121 tttgaaggaa atgattaaag ccattttcta tgaacataaa gagcgttacg gaagtgtacg
      181 aattacccaa gaactttgta gacgtggcat ccatgtcaat cataaacgtg ttggtagact
      241 ccttcatcag ctaggtctct atgctaaagg aagtcgatat caatataaat act
//
LOCUS       DAUCXI010000121          288 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.130, whole genome shotgun sequence.
ACCESSION   DAUCXI010000121 DAUCXI010000000
VERSION     DAUCXI010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.130"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            <1..>288
                     /locus_tag="VGY43_001824"
     CDS             <1..>288
                     /locus_tag="VGY43_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HEQ4302954.1"
                     /translation="EMNEPLFATYVDLSEGCPSHDTLERVISLVNSDRLKELKVQFEQ
                     SLTSLDAVHQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVEE"
BASE COUNT           83 a           45 c           73 g           87 t
ORIGIN      
        1 tgaaatgaat gaaccattgt ttgcgaccta cgttgatttg agtgaaggtt gtccgtctca
       61 tgatacctta gagcgtgtga ttagtcttgt taattcagac cgtttaaaag agcttaaagt
      121 tcaatttgag caatcattga caagcttaga tgccgttcat caactgattt cagtggacgg
      181 taaaacgatt cgaggcaatc gaggtaaaaa tcagaagcct gttcatattg taacggctta
      241 tgatgggggt catcatctta gtttgggaca ggtagcggtt gaggagaa
//
LOCUS       DAUCXI010000122          261 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.denovo.131, whole genome shotgun sequence.
ACCESSION   DAUCXI010000122 DAUCXI010000000
VERSION     DAUCXI010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..261
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.denovo.131"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            complement(87..171)
                     /locus_tag="VGY43_001825"
     tRNA            complement(87..171)
                     /locus_tag="VGY43_001825"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(135..137),aa:Leu,seq:taa)
     gene            complement(180..251)
                     /locus_tag="VGY43_001826"
     tRNA            complement(180..251)
                     /locus_tag="VGY43_001826"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(217..219),aa:Gly,seq:gcc)
BASE COUNT           67 a           77 c           59 g           58 t
ORIGIN      
        1 ccctagagga gtcgaacctc taaccgcctg attcgtagtc aggtactcta tccagttgag
       61 ctaagggtgc tatttcaaaa aattaatgcc gaggaccgga atcgaaccgg tacgatgtaa
      121 accatcgcag gattttaagt cctgtgcgtc tgccagttcc gccaccccgg ctcctcaaaa
      181 gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtgatgtt ctaccactga
      241 actacgttcg caactaatct c
//
LOCUS       DAUCXI010000123         3124 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.guided.084, whole genome shotgun sequence.
ACCESSION   DAUCXI010000123 DAUCXI010000000
VERSION     DAUCXI010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3124
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.guided.084"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            1..756
                     /locus_tag="VGY43_001827"
                     /pseudo
     CDS             1..756
                     /locus_tag="VGY43_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            1001..1117
                     /locus_tag="VGY43_001828"
     CDS             1001..1117
                     /locus_tag="VGY43_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEQ4302955.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            1133..3052
                     /gene="tet(M)"
                     /locus_tag="VGY43_001829"
     CDS             1133..3052
                     /gene="tet(M)"
                     /locus_tag="VGY43_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEQ4302956.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT         1053 a          499 c          633 g          939 t
ORIGIN      
        1 ggtactttta gggcttagtt tcagctttgc gatattcaag cactttacag ctatagatac
       61 tcatactatt cacgaaacaa ctatcataga aaaggaatac gttgatactc atcatgtaga
      121 aaattttgta gagaactttg cgaaagtcta aaaggctatc tgacagatga acttcaagct
      181 ctcaatgttg atacagtacg caaagatatt cctgtatcgt cttctgtaag aggatttcag
      241 atatggacgg tagagccaac tggcgacaat gagtttaatg taacctacag tgtagaccag
      301 ctcattacag agggagaaaa tacaaagacc gtccactctg cttatatagt gagtgtctat
      361 gtagatggtt ctggaaatat ggtactggtt aagaatccga ccattaccaa catacctaag
      421 aaatcaagtt ataaaccaaa agccattgaa agtgagggga cggttgattc cattacaacc
      481 aatgaaatca atgagttttt aacgacgttc ttcaagctct atcctacagc gacagccagt
      541 gaactttcct actatgtgaa tgacgggata ttaaaaccaa tcggaaaaga gtacatcttt
      601 caagaactgg taaatcctat tcacaatcgt aaggataatc aagtcacggt atcgctgaca
      661 gtggagtata tcgaccagca gaccaaagca acgcaggtat ctcaatttga tttggtactt
      721 gaaaagaacg ggagtaattg gaagattata gaataacaaa tattggtaca ttattacagc
      781 tattttgtaa tcacgtactc tctttgataa aaaattggag attcctttac aaatatgctc
      841 ttacgtgcta taatttaagt atctatttaa aaggagttaa taaatatgcg gcaaggtatt
      901 cttaaataaa ctgtcaattt gatagtggga acaaataatt ggatgtcctt ttttaggagg
      961 gcttagtttt ttgtacccag tttaagaata cctttatcat gtgattctaa agtatccgga
     1021 gaatatctgt atgctttgta tgcctatggt tatgcataaa aatcccagtg ataagagtat
     1081 ttatcactgg gatttttatg cccttttggg cttttgaatg gaggaaaatc acatgaaaat
     1141 tattaatatt ggagttttag ctcatgttga tgcgggaaaa actaccttaa cagaaagctt
     1201 attatataac agtggagcga ttacagaatt aggaagcgtg gacaaaggta caacgaggac
     1261 ggataatacg cttttagaac gtcagagagg aattacaatt cagacaggaa taacctcttt
     1321 tcagtgggaa aatacgaagg tgaacatcat agacacgcca ggacatatgg atttcttagc
     1381 agaagtatat cgttcattat cagttttaga tggggcaatt ctactgattt ctgcaaaaga
     1441 tggcgtacaa gcacaaactc gtatattatt tcatgcactt aggaaaatgg ggattcccac
     1501 aatctttttt atcaataaga ttgaccaaaa tggaattgat ttatcaacgg tttatcagga
     1561 tattaaagag aaactttctg ccgaaattgt aatcaaacag aaggtagaac tgtatcctaa
     1621 tatgtgtgtg acgaacttta ccgaatctga acaatgggat acggtaatag agggaaacga
     1681 tgacctttta gagaaatata tgtccggtaa atcattagaa gcattggaac tcgaacaaga
     1741 ggaaagcata agatttcaga attgttctct gttccctctt tatcatggaa gtgcaaaaag
     1801 taatataggg attgataacc ttatagaagt tattactaat aaattttatt catcaacaca
     1861 tcgaggtcag tctgaacttt gcggaaaagt tttcaaaatt gagtattcgg aaaaaagaca
     1921 gcgtcttgca tatatacgtc tttatagtgg cgtactgcat ttgcgagatt cggttagaat
     1981 atcggaaaag gaaaaaataa aaattacaga aatgtatact tcaataaatg gtgaattatg
     2041 taaaatcgat aaggcttatt ccggggaaat tgttattttg cagaatgagt ttttgaagtt
     2101 aaatagtgtt cttggagata caaagctatt gccacagaga gagagaattg aaaatcccct
     2161 ccctctgctg caaacgactg ttgaaccgag caaacctcaa caaagggaaa tgttacttga
     2221 tgcactttta gaaatctccg acagtgaccc gcttctgcga tattatgtgg attctgcgac
     2281 acatgaaatc atactttctt tcttagggaa agtacaaatg gaagtgactt gtgctctgct
     2341 gcaagaaaag tatcatgtgg agatagaaat aaaagagcct acagtcattt atatggaaag
     2401 accgttaaaa aaagcagagt ataccattca catcgaagtt ccaccgaatc ctttctgggc
     2461 ttccattggt ctatctgtag cacagcttcc attagggagc ggagtacagt atgagagctc
     2521 ggtttctctt ggatacttaa atcaatcgtt tcaaaatgca gttatggagg ggatacgcta
     2581 tggctgtgaa caaggattgt atggttggaa tgtgacggac tgtaaaatct gttttaagta
     2641 tggcttatac tatagccctg ttagtacccc agcagatttt cggatgcttg ctcctattgt
     2701 attggaacaa gtcttaaaaa aagctggaac agaattgtta gagccatatc ttagttttaa
     2761 aatttatgcg ccacaggaat atctttcacg agcatacaac gatgctccta aatattgtgc
     2821 gaacatcgta gacactcaat tgaaaaataa tgaggtcatt cttagtggag aaatccctgc
     2881 tcggtgtatt caagaatatc gtagtgattt aactttcttt acaaatggac gtagtgtttg
     2941 tttaacagag ttaaaagggt accatgttac taccggtgaa cctgtttgcc agccccgtcg
     3001 tccaaatagt cggatagata aagtacgata tatgttcaat aaaataactt agtgtatttt
     3061 atgttgttat ataaatatgg tttcttgtta aataagatga aatatttttt aataaagatt
     3121 tgaa
//
LOCUS       DAUCXI010000124         1007 bp    DNA     linear   BCT 01-JAN-2024
DEFINITION  TPA_asm: Streptococcus pyogenes strain TG134348
            SAMN37094623-rid19215423.guided.109, whole genome shotgun sequence.
ACCESSION   DAUCXI010000124 DAUCXI010000000
VERSION     DAUCXI010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37094623
            Sequence Read Archive: SRR25711354
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001859328.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001859328.1
            Genome Coverage       :: 128x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/23/2023 18:27:46
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,830
            CDSs (total)                      :: 1,792
            Genes (coding)                    :: 1,728
            CDSs (with protein)               :: 1,728
            Genes (RNA)                       :: 38
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 64
            CDSs (without protein)            :: 64
            Pseudo Genes (ambiguous residues) :: 0 of 64
            Pseudo Genes (frameshifted)       :: 41 of 64
            Pseudo Genes (incomplete)         :: 22 of 64
            Pseudo Genes (internal stop)      :: 14 of 64
            Pseudo Genes (multiple problems)  :: 11 of 64
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1007
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37094623-rid19215423.guided.109"
                     /strain="TG134348"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="USA: ARIZONA"
                     /collection_date="2019-08-12"
                     /collected_by="Arizona State Public Health Laboratory"
     gene            21..758
                     /gene="erm(B)"
                     /locus_tag="VGY43_001830"
     CDS             21..758
                     /gene="erm(B)"
                     /locus_tag="VGY43_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEQ4302957.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          362 a          171 c          165 g          309 t
ORIGIN      
        1 atcacttcag gagtgattac atgaacaaaa atataaaata ttctcaaaac tttttaacga
       61 gtgaaaaagt actcaaccaa ataataaaac aattgaattt aaaagaaacc gataccgttt
      121 acgaaattgg aacaggtaaa gggcatttaa cgacgaaact ggctaaaata agtaaacagg
      181 taacgtctat tgaattagac agtcatctat tcaacttatc gtcagaaaaa ttaaaactga
      241 acattcgtgt cactttaatt caccaagata ttctacagtt tcaattccct aacaaacaga
      301 ggtataaaat tgttgggaat attccttacc atttaagcac acaaattatt aaaaaagtgg
      361 tttttgaaag ccatgcgtct gacatctatc tgattgttga agaaggattc tacaagcgta
      421 ccttggatat tcaccgaaca ctagggttgc tcttgcacac tcaagtctcg attcagcaat
      481 tgcttaagct gccagcggaa tgctttcatc ctaaaccaaa agtaaacagt gtcttaataa
      541 aacttacccg ccataccaca gatgttccag ataaatattg gaagctatat acgtactttg
      601 tttcaaaatg ggtcaatcga gaatatcgtc aactgtttac taaaaatcag tttcatcaag
      661 caatgaaaca cgccaaagta aacaatttaa gtaccgttac ttatgagcaa gtattgtcta
      721 tttttaatag ttatctatta tttaacggga ggaaataatt ctatgagtcg cttttgtaaa
      781 tttggaaagt tacacgttac taaagggaat gtagataaat tattaggtat actactgaca
      841 gcttccaagg agctaaagag gtccctagcg cctacgggga atttgtatcg ataaggaata
      901 gatttaaaaa tttcgctgtt attttgtaca ataaggataa atttgaatgg taccataaac
      961 gaccgtttat ggtacctttt cattttcctg ctttttctaa atgtttt
//
